diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c469599d02d41475983c62d693fa902017d1afeb --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:05984ef2f09bd6901e6b08c0432d33fbc72cea4a01811ee3d8dd40ca8abec5dc +size 75310 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..dbebc79aa787612ca00de13292d2fa0084712d09 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 55, + "title": "Average number of proteins per term", + "value": 2.6 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b3a49a1d6f7816d9642f44ce043261d6dabc6fe2 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..986faa9b076b4be0fee7e25a82c710520494b1ce --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Histidine acid phosphatase active site [IPR033379] 0.9048716260697712 1.5689387715455432 0.1166622065728513 0.9989111334363204 0.2212559090174766 2 Q9NPH0 1 +Serine carboxypeptidase, serine active site [IPR018202] 0.8337174843595558 1.1959529674396876 0.2317149134628087 0.9999994944871892 0.3861915224380145 3 Q9HB40,P10619 2 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..99820eb166935736febd6ddc61f076488bd3496f --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MDH1", "MDH2", "MTMR2", "NEK9", "NME1", "NME2", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE2T", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["ACP6", "CTSA", "SCPEP1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ab243a088656304ea430bb11e6a795d0b5ab736a --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:db5b4107151f307522146d599b58cbf92fb54be09d6cda4cc454ef971446fb15 +size 140038 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0cd6ab13c5493d67f2708c92ef54caf8e5974f20 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ccde957cacfb8108894bd3b6f8741570625c19aed66b4982d24dea4bdfc6a195 +size 69787 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a6f66c675d97dc5a054ab3bd950930dbc5eaa0b0 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 31, + "title": "Average number of proteins per term", + "value": 4.548387096774194 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b8489a0b54773568900f68c3d75054967f47e16f --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dee4a0ff24116d3a588d80cc4ccfa6243e91e61d --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EF-Hand 1, calcium-binding site [IPR018247] 0.392248662986251 1.5426689738837285 0.1229111134420357 0.9828465352911512 0.2772725117467243 40 P80303,Q14257,P0DP25,Q9Y680,Q6NUK1,O95302,Q02818,Q9NWM8,P41208 9 +Peptidase M16, zinc-binding site [IPR001431] 0.4885120053524056 0.6016144977973463 0.5474307761748078 0.9999999999788048 0.6087463876737773 5 Q10713 1 +Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.6675444371296919 0.5980067233751343 0.5498354469311537 0.9999999999820316 0.6087463876737773 2 O15270 1 +Beta tubulin, autoregulation binding site [IPR013838] 0.4629324546952163 0.492266605027309 0.6225308847600735 0.9999999999999236 0.6553809025492945 5 P07437,P04350,P68371,Q9BUF5 4 +Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798] 0.5757077024358063 0.3023579050934096 0.7623792407149717 1.0 0.7623792407149717 2 P34896 1 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d4149a433594b3a92728a3501e9114cf2780b330 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "ITSN2", "LETM1", "LPCAT2", "MACF1", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TKT", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CALM3", "CETN2", "FKBP14", "FKBP7", "FKBP9", "NUCB1", "NUCB2", "PMPCA", "RCN2", "SHMT1", "SLC25A24", "SPTLC2", "TUBB", "TUBB4A", "TUBB4B", "TUBB6"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..145d3e094c2aef400b7d961308f40852f8d581eb --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Syntaxin/epimorphin, conserved site [IPR006012]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..6624db71d279ab39e7602ea6dfdc54eaea33c051 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4c7fa180bd221ab4f0b317adafa5f83e5df1262258ea390f921911dc5f0f9953 +size 186635 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..698b9ef516b384091ab9e6b7bef9b82a4d029e5c --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Syntaxin/epimorphin, conserved site [IPR006012]", "1": "14-3-3 protein, conserved site [IPR023409]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a91deaaa3b02895c5c34f7e9d7e3c5e440071cbb --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4c48f47e3d341586879b72d220172f5783e68d9ba86f2703521301ab6888298d +size 144974 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..455100e1342a5ee7d7d242d7ca85249a332b5b38 --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6daae14d7a9ea6783b21a1b93002b9bafc6bea56b7859fef50d7671ca870edf2 +size 141165 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..8de09a2b2816b0b40a255f2cdd93693a5af66563 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4e3b6333fceebab9d8eb3854a2e78a12970c90a44e69d7b169d80c6a2fc3c125 +size 97795 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5dfb5233042e78aa28be24223ebaa453121a20df --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Syntaxin/epimorphin, conserved site [IPR006012] 6 8 2.4084260946829263 0.0160214697670266 2.592233009708738 5.847087378640777 0.9961908981999794 0.2839139128702306 1.4759357288864456 1.4239341993278547 1.138258151200134 0.2914162845337057 0.0011015965796577 0.0607401038440192 0.1180585699575878 0.0382400085743442 1.6468344784532795e-05 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bea80b1580ba344d4443fa5af7fc3ba8cb4381b0 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 271, + "title": "Average number of proteins per term", + "value": 2.5830258302583027 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5cb53ecea7fe569b663ebad3118f8f10dd97ee19 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fc9b11a6edaee1788630549b603cbd082720a4a0 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,22 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Syntaxin/epimorphin, conserved site [IPR006012] 0.8046786731159765 2.4084260946829263 0.0160214697670266 0.9874367008466088 0.1027728186312747 8 P56962,O15400,O43752,Q9P2W9,Q13277,Q13190 6 +Haem oxygenase conserved site [IPR018207] 0.9888084265964436 1.9236635497818748 0.0543967697252369 0.9999997387088664 0.1842690574442403 2 P09601 1 +Thioredoxin, conserved site [IPR017937] 0.5394092088648637 1.5667348560571512 0.1171766798579851 0.999999999999998 0.3342618972790945 12 P07237,Q96JJ7,Q9H1E5 3 +Tetraspanin, conserved site [IPR018503] 0.8749177090190711 1.4415949256462506 0.1494166807858103 1.0 0.3864806070561967 2 O43657 1 +Polyprenyl synthetase, conserved site [IPR033749] 0.8676761026991445 1.410811594357241 0.1583001748458961 1.0 0.3864806070561967 2 Q5T2R2 1 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.8077682685977624 1.1572843432935744 0.2471562080862368 1.0 0.5014740542008198 2 Q9BTY2 1 +Intermediate filament protein, conserved site [IPR018039] 0.5447771795255602 1.106847540018514 0.2683598502282822 1.0 0.5232051756249243 8 Q16352,P07196,P08670 3 +3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.7722185648452711 1.0090634346706262 0.3129442127738726 1.0 0.5790380659536397 2 Q16836 1 +Proteasome beta-type subunit, conserved site [IPR016050] 0.5134475574253535 0.9418221015027792 0.3462837276836008 1.0 0.6015569884759989 8 P28070,P49721 2 +Sugar transporter, conserved site [IPR005829] 0.7093482554311825 0.7558509768751153 0.4497385490312877 1.0 0.6457806590376296 2 Q7L0J3 1 +C-type lectin, conserved site [IPR018378] 0.708689927583938 0.7532865433381917 0.4512777433862711 1.0 0.6457806590376296 2 Q9UBG0 1 +Guanylate kinase, conserved site [IPR020590] 0.5202635914332723 0.742924723155322 0.4575272565875456 1.0 0.6457806590376296 5 Q00013,Q5T2T1,Q14168,O14936 4 +EGF-like, conserved site [IPR013032] 0.6445029624753141 0.5162199165978113 0.605700821436691 1.0 0.7495201945632112 2 O94813 1 +EGF-like calcium-binding, conserved site [IPR018097] 0.6445029624753141 0.5162199165978113 0.605700821436691 1.0 0.7495201945632112 2 O94813 1 +Tubulin, conserved site [IPR017975] 0.4629324546952166 0.4922666050273103 0.6225308847600726 1.0 0.7537863163071451 5 P07437,P04350,P68371,Q9BUF5 4 +Actin, conserved site [IPR004001] 0.5868992758393696 0.3335422483937915 0.7387250037752482 1.0 0.8341436500962177 2 P61163 1 +14-3-3 protein, conserved site [IPR023409] 0.3991430454845158 0.3245130311572731 0.7455496581804859 1.0 0.8383566695722476 6 P27348,P31946,P62258,P63104,Q04917 5 +S100/Calbindin-D9k, conserved site [IPR001751] 0.5543120473996068 0.2471960724604582 0.8047564847288204 1.0 0.8846082139390784 2 P31949 1 +RNA polymerase, beta subunit, conserved site [IPR007121] 0.4878209348255453 0.1161215152916007 0.9075562374250016 1.0 0.9569950986076866 2 P30876 1 +Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.4282422646477968 0.0497229101535463 0.9603431993759924 1.0 0.9820868189845054 2 P82675 1 +D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752] 0.2748518762343674 0.00969018452204 0.9922684723767126 1.0 1.0 2 O43175 1 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bf6956d762cb692b2679559a124576f6dba5efff --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycerate/sugar phosphate transporter, conserved site [IPR021159]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "PTR2 family proton/oligopeptide symporter, conserved site [IPR018456]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase, RluC/RluD, conserved site [IPR006224]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APP", "ATAD1", "ATAD2", "ATG16L1", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BRD2", "BRPF1", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CHD5", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC2", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD2", "NSF", "NTHL1", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIK3C3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR2F", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRP8", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC15A4", "SLC1A5", "SLC27A4", "SLC2A1", "SLC37A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN6", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ACTR1A", "CASK", "FUCA2", "HADH", "HMOX1", "INA", "MPP1", "MPP2", "MPP7", "MRC2", "MRPS5", "NEFL", "P4HB", "PDSS1", "PHGDH", "POLR2B", "PSMB2", "PSMB4", "S100A11", "SLIT2", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "SV2A", "TMX3", "TMX4", "TSPAN6", "TUBB", "TUBB4A", "TUBB4B", "TUBB6", "VIM", "YWHAB", "YWHAE", "YWHAH", "YWHAQ", "YWHAZ"]} \ No newline at end of file diff --git a/interpro_domain/advanced/idx2term.json b/interpro_domain/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..3345ddee539052b0f99e603f787a70a11e32e97f --- /dev/null +++ b/interpro_domain/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Target SNARE coiled-coil homology domain [IPR000727]", "1": "Importin-beta, N-terminal domain [IPR001494]"} \ No newline at end of file diff --git a/interpro_domain/advanced/plot_0.png b/interpro_domain/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ddeb27af4dc26b49ea1d0a87174d8865fb048f70 --- /dev/null +++ b/interpro_domain/advanced/plot_0.png @@ -0,0 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domain [IPR002048]", "4": "Major facilitator superfamily domain [IPR020846]", "5": "Band 7 domain [IPR001107]", "6": "14-3-3 domain [IPR023410]", "7": "Small GTP-binding protein domain [IPR005225]"} \ No newline at end of file diff --git a/interpro_domain/basic/plot_0.png b/interpro_domain/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..0aaadb0adea45a5d7d4f30c56e238a4768292ea5 --- /dev/null +++ b/interpro_domain/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:017739acbf160bc1905e3dab3a89947a2d163858866c874e2a8ec4dc83719ad4 +size 143699 diff --git a/interpro_domain/basic/plot_1.png b/interpro_domain/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..dd040ca080079ff75e45a48194b20d593f6c84a0 --- /dev/null +++ b/interpro_domain/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2ec8b21ca5cb366b57925e833e9bc984944e4baf2b772ce2a4420253efe00208 +size 138181 diff --git a/interpro_domain/basic/plot_2.png b/interpro_domain/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..a0857e6d2b8ce3749c51b3d60b747be98373c770 --- /dev/null +++ b/interpro_domain/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7ff3fd196bb9a0e0cc79e02cacdd6d5e72ddb9aa5d07db32ec49ed87152ccec7 +size 143721 diff --git a/interpro_domain/basic/plot_3.png b/interpro_domain/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..5eeffa0008ffb6f179ad75208a8df18f54d31be5 --- /dev/null +++ b/interpro_domain/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ac03d88b8d9980faceb206616b3f0c17995fa658205cf093cfd2ffe63e0cae7d +size 131873 diff --git a/interpro_domain/basic/plot_4.png b/interpro_domain/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..8ffbbd4a9e2190e9d3a8810beee49c4e4255ce7c --- /dev/null +++ b/interpro_domain/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ef925d7dc876b3f388eeb7264ba25b57760d26e6d4e02c3143757434f3f910d4 +size 139815 diff --git a/interpro_domain/basic/plot_5.png b/interpro_domain/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..4efb2245baf6a7bedd9bc046a6394b7b68a3783e --- /dev/null +++ b/interpro_domain/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5ea31200ebc1bb5452e5fa11e0408e9f4457176c8fd85487ea1b0bf31d00b66d +size 130765 diff --git a/interpro_domain/basic/plot_6.png b/interpro_domain/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..26bb7d4f38d2277a212004df5060296b206aece8 --- /dev/null +++ b/interpro_domain/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:41c07482e9edeeff36d74cdd1a442acf2a152084bc0bad192104c536e372f6c8 +size 133799 diff --git a/interpro_domain/basic/plot_7.png b/interpro_domain/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..c93e470425c2b62b3ce60d023e73e7fb4e6d96b9 --- /dev/null +++ b/interpro_domain/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c6951c773712fd6bb2e480084ad1e3a92ecca33dce69c599fcd31099db92e990 +size 156391 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..b0f1e8f4c9583fb9cdea170acb5a2941d362ab29 --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a0bb4f6410019bcf9d3cbf464b831647c3ae47730c7b07acdd033d179ffe4656 +size 304179 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0cd71698d1b242aab48e78fada03b69bbab7929a --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Target SNARE coiled-coil homology domain [IPR000727] 8 12 2.5048035358053213 0.0122519427380496 3.5024271844660193 8.266990291262136 0.5942034778060385 0.4012381903331891 1.9023475359698396 2.183694577914796 1.0582363712887182 0.3038263160802639 0.0136183078461816 1.0 1.0 0.4587195489148998 0.0001380877092489 +Importin-beta, N-terminal domain [IPR001494] 8 13 2.422400514640592 0.0154183468266064 6.385922330097087 13.28883495145631 0.1695856896111973 0.5104356360219653 3.297409379395681 0.8134617396566306 1.1027535719761996 0.3475482514742156 0.4813935862458969 1.0 1.0 0.3411306657380243 0.0468003866103798 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 3 5 2.138097496124056 0.0325088311202219 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0001254368379847 1.0 0.0743799864466655 0.0148625463558957 0.0003311660608568 +Aminopeptidase N-like , N-terminal domain [IPR045357] 3 5 2.138097496124056 0.0325088311202219 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0001254368379847 1.0 0.0743799864466655 0.0148625463558957 0.0003311660608568 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 2 6 1.9622407626612277 0.049734460230614 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0091783194539023 0.0561990347849709 0.1094892401774078 0.0328731354880699 0.0181181417645757 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..abe8c5d79926ad6f3d287f5c0764ddaa34b1afa0 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 2522, + "title": "Average number of proteins per term", + "value": 2.120539254559873 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..fb256d55b77d9aeb068fce22aa25afcb6b2bcd82 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..49d5f3f2b8560a76197a2fa722936eb2ebc8d5f9 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,190 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Target SNARE coiled-coil homology domain [IPR000727] 0.6972206788968138 2.5048035358053213 0.0122519427380496 0.9999999999999686 0.1276745511673693 12 Q86Y82,P56962,O15400,O43752,Q13277,Q9UEU0,O15155,Q13190 8 +Importin-beta, N-terminal domain [IPR001494] 0.6557478622551338 2.422400514640592 0.0154183468266064 1.0 0.1309527677047245 13 Q8TEX9,Q92973,O43592,O15397,O95373,P55060,Q96P70,Q9HAV4 8 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.8246657077284575 2.138097496124056 0.0325088311202219 1.0 0.1646392377153801 5 Q9NZ08,P09960,Q9UIQ6 3 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.8246657077284575 2.138097496124056 0.0325088311202219 1.0 0.1646392377153801 5 Q9NZ08,P09960,Q9UIQ6 3 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.7376110304708573 1.9622407626612273 0.049734460230614 1.0 0.2076660740092856 6 O43169,O15173 2 +Immunoglobulin-like domain [IPR007110] 0.6747728879662407 1.931689330184856 0.0533978625090136 1.0 0.2157788971293487 9 P10321,P35613,P04439,Q08722 4 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.7288478249605723 1.9206876619717992 0.0547710959997362 1.0 0.2170187342356873 6 P16615,Q9HD20,P98194,P05023 4 +GOLD domain [IPR009038] 0.7251177669453573 1.9029459238513449 0.0570476017304217 1.0 0.2230605450606569 6 P49755,Q9Y3B3,Q15363 3 +START domain [IPR002913] 0.9631336405529912 1.815697091820387 0.0694168504246062 1.0 0.2493864626365482 2 Q14849 1 +Phospholipid/glycerol acyltransferase [IPR002123] 0.683161403384659 1.7899617008752982 0.0734600685841435 1.0 0.2548367166013893 7 Q86UL3,Q9NUQ2,Q7L5N7,Q8NF37,Q92604 5 +EF-hand domain [IPR002048] 0.4094164475637834 1.7872886283173344 0.0738908510197691 1.0 0.2555406215427682 46 O43852,P80303,Q14257,Q8IYU8,O75071,P0DP25,Q9BRK5,Q9Y680,Q6NUK1,O95302,Q02818,Q9NWM8,Q8NF37,P41208 14 +Major facilitator superfamily domain [IPR020846] 0.6719419716452145 1.734188919214408 0.0828845683948655 1.0 0.2772345908379987 7 Q14728,Q7L0J3,P11166,O43826,Q9H2V7,Q6NT16 6 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.6054404648148898 1.722004529733052 0.0850686979392743 1.0 0.2815528296625325 10 Q9Y680,Q9NWM8,P62942,O95302 4 +Band 7 domain [IPR001107] 0.6634007185640727 1.72110799654933 0.0852312284978153 1.0 0.2817210462273793 8 Q99623,O75477,Q9UJZ1,P27105,O94905 5 +MENTAL domain [IPR019498] 0.9371296905859032 1.7058049179211745 0.0880444071795318 1.0 0.2865135418151992 2 Q14849 1 +GMP phosphodiesterase, delta subunit [IPR008015] 0.9364713627386372 1.703016916117195 0.0885649027595625 1.0 0.2868167825391938 2 A6NIH7 1 +Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709] 0.9321922317314024 1.684888705552279 0.0920100460675372 1.0 0.2926221137229873 2 P16435 1 +Oxidoreductase FAD/NAD(P)-binding [IPR001433] 0.9321922317314024 1.684888705552279 0.0920100460675372 1.0 0.2926221137229873 2 P16435 1 +FAD-binding domain, ferredoxin reductase-type [IPR017927] 0.9321922317314024 1.684888705552279 0.0920100460675372 1.0 0.2926221137229873 2 P16435 1 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.8476909646031103 1.680980400442545 0.0927667216024585 1.0 0.2939166732178399 4 Q15629,Q96G23 2 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.6527247571825523 1.6379643213623651 0.1014291367379773 1.0 0.2984880780083768 7 O60313,Q8IWA4,O00429 3 +Dynamin, N-terminal [IPR045063] 0.6527247571825523 1.6379643213623651 0.1014291367379773 1.0 0.2984880780083768 7 O60313,Q8IWA4,O00429 3 +Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.91310072416062 1.6038950996736852 0.10873717716534 1.0 0.3042237523049474 2 Q9Y282 1 +Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.91310072416062 1.6038950996736852 0.10873717716534 1.0 0.3042237523049474 2 Q9Y282 1 +Peptidase M48 [IPR001915] 0.9101382488479148 1.5913133444710004 0.1115390751125691 1.0 0.307441509274537 2 O75844 1 +Peptidase M16, C-terminal [IPR007863] 0.635929756946517 1.5531858631748496 0.1203787376673555 1.0 0.3216050597426595 7 Q5JRX3 1 +Peptidase M16, N-terminal [IPR011765] 0.635929756946517 1.5531858631748496 0.1203787376673555 1.0 0.3216050597426595 7 Q5JRX3 1 +Reticulon [IPR003388] 0.9213039183404628 1.5392566968634347 0.1237416410570291 1.0 0.3271241286643893 3 Q9NQC3,O95197 2 +Immunoglobulin subtype 2 [IPR003598] 0.6727798944604971 1.45170454519973 0.1465837749722411 1.0 0.358916777165041 5 P35613 1 +Immunoglobulin subtype [IPR003599] 0.6727798944604971 1.45170454519973 0.1465837749722411 1.0 0.358916777165041 5 P35613 1 +Protein kinase, C-terminal [IPR017892] 0.6692802322549389 1.4354493907020287 0.1511590801758928 1.0 0.3665607694265402 5 P51812,Q05655,Q15418 3 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.7875494071146304 1.431061098876443 0.1524127050330188 1.0 0.3673695581195915 4 P05023,P16615,P98194 3 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.7875494071146304 1.431061098876443 0.1524127050330188 1.0 0.3673695581195915 4 P05023,P16615,P98194 3 +Tim10-like [IPR004217] 0.7823465317840146 1.409312144671934 0.158742889280623 1.0 0.3750265340499959 4 P62072,Q9Y5J9 2 +MD-2-related lipid-recognition domain [IPR003172] 0.8647136273864255 1.3982217544957078 0.1620464859685202 1.0 0.3773603302055476 2 P17900 1 +YTH domain [IPR007275] 0.6568446639172189 1.377582162685787 0.1683323312711389 1.0 0.384890425626303 5 Q7Z739,Q9Y5A9 2 +ERAP1-like C-terminal domain [IPR024571] 0.8765228844254134 1.3636927728617638 0.1726642796053845 1.0 0.3902287982901509 3 Q9NZ08,Q9UIQ6 2 +Acyl-CoA oxidase, C-terminal [IPR002655] 0.8475971033574727 1.3255444619543282 0.1849906327747317 1.0 0.4049881734877373 2 O15254 1 +FAD dependent oxidoreductase [IPR006076] 0.7602108036890642 1.3166504216056103 0.1879558292858831 1.0 0.4081785714290186 4 Q8NCN5,Q96CU9,P43304 3 +Zinc finger, CHHC-type [IPR012996] 0.8594007243990773 1.2965282922203316 0.1947935392680762 1.0 0.4121386795587988 3 P55795,P52597 2 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.8393680052666231 1.2906598807443812 0.1968216420444946 1.0 0.4157321450889576 2 Q14011 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.8373930217248196 1.2822947748660996 0.1997392602235645 1.0 0.4183907095380647 2 O60506 1 +Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906] 0.8357472021066377 1.275326216878231 0.2021938020269671 1.0 0.4221297754238502 2 P51812 1 +LEM domain [IPR003887] 0.5916100941755201 1.2491996850246008 0.2115920471821648 1.0 0.4345563053692343 6 Q86XL3,P42167 2 +CARG-binding factor, N-terminal [IPR012956] 0.8206056616194872 1.211333138357468 0.2257677531463162 1.0 0.4504638239201025 2 Q99729 1 +Syntaxin, N-terminal domain [IPR006011] 0.8320711228185693 1.1895180192225572 0.234235884581734 1.0 0.4568777269258572 3 Q13277,O15400 2 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8120473996050039 1.1752761628146475 0.2398842479519007 1.0 0.4621757626697431 2 Q5T9A4 1 +Dynamin, GTPase domain [IPR001401] 0.8267694017136431 1.168809173180804 0.2424805236913727 1.0 0.4636359975357407 3 O60313 1 +Intermediate filament head, DNA-binding domain [IPR006821] 0.7246376811594191 1.1676142170505406 0.2429624128563206 1.0 0.4642054585027579 4 Q16352,P07196,P08670 3 +Choline/carnitine acyltransferase domain [IPR039551] 0.8097432521395419 1.1655850178297382 0.2437822681858401 1.0 0.4650884297092342 2 P23786 1 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.8077682685977624 1.1572843432935744 0.2471562080862368 1.0 0.4679065220169759 2 Q9BTY2 1 +N-acetylgalactosaminyltransferase [IPR045885] 0.8028308097432348 1.1365583189788224 0.2557229727866255 1.0 0.4752640658569414 2 Q10472 1 +TGS [IPR004095] 0.5659462380894109 1.1206781020253926 0.2624249065706978 1.0 0.4827393248514223 6 Q9NTK5 1 +Intermediate filament, rod domain [IPR039008] 0.5447771795255602 1.106847540018514 0.2683598502282822 1.0 0.4890399374154204 8 Q16352,P07196,P08670 3 +Far upstream element-binding protein, C-terminal [IPR015096] 0.7863726135615546 1.067773275032234 0.2856227960149549 1.0 0.5008892273532343 2 Q92945 1 +Glycosyltransferase 2-like [IPR001173] 0.7958511689166861 1.048583732668242 0.2943697460616148 1.0 0.5088831660328128 3 Q10472,Q10471 2 +3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.7722185648452711 1.0090634346706262 0.3129442127738726 1.0 0.5251133097908894 2 Q16836 1 +3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.7722185648452711 1.0090634346706262 0.3129442127738726 1.0 0.5251133097908894 2 Q16836 1 +Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.5262956557902334 0.988882808141752 0.3227204828175041 1.0 0.5337056115840954 7 Q8NEB9,Q9BTU6 2 +Sam68, tyrosine-rich domain [IPR032335] 0.7639894667544336 0.9751562967795592 0.3294827368120838 1.0 0.5390666935806543 2 O75525 1 +KHDRBS, Qua1 domain [IPR032571] 0.7639894667544336 0.9751562967795592 0.3294827368120838 1.0 0.5390666935806543 2 O75525 1 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.7613561553653727 0.9643451808247772 0.3348728962745131 1.0 0.5434681109422922 2 P13674 1 +Post-SET domain [IPR003616] 0.7570770243581314 0.946820248068699 0.34373038220682 1.0 0.5521657448089982 2 O96028 1 +FAD-binding domain, PCMH-type [IPR016166] 0.7551020408162946 0.9387504906198344 0.3478588636305602 1.0 0.5531592866538241 2 Q15392 1 +FAD linked oxidase, N-terminal [IPR006094] 0.7551020408162946 0.9387504906198344 0.3478588636305602 1.0 0.5531592866538241 2 Q15392 1 +Glycoside hydrolase family 2, catalytic domain [IPR006103] 0.7534562211981355 0.932034990706798 0.3513184426021958 1.0 0.5551146485434272 2 P08236 1 +Rhodanese-like domain [IPR001763] 0.7643785273162309 0.9276389234799426 0.3535949000509419 1.0 0.5565842655270653 3 Q8NCN5 1 +Acyltransferase, C-terminal domain [IPR032098] 0.747860434496349 0.909267860819746 0.3632087510947897 1.0 0.5638258130107159 2 Q9NUQ2 1 +Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252] 0.7566677642410211 0.8983167188599119 0.369016721720242 1.0 0.5674757147429575 3 Q8NF37,Q7L5N7 2 +Fzo/mitofusin HR2 domain [IPR006884] 0.7369980250164592 0.8653830946730866 0.3868285565971101 1.0 0.5866395789163631 2 Q8IWA4 1 +Acyl transferase [IPR014043] 0.7314022383146664 0.8429492735141532 0.3992568144029624 1.0 0.5965199561162745 2 Q8IVS2 1 +Exportin-2, central domain [IPR013713] 0.7411919657556681 0.8399272057211852 0.400949202619806 1.0 0.5966835312734471 3 O95373,O15397 2 +Peptidase M14, carboxypeptidase A [IPR000834] 0.7300855826201459 0.8376889984927226 0.4022053938004997 1.0 0.5966835312734471 2 P16870 1 +AGC-kinase, C-terminal [IPR000961] 0.4937360578534181 0.820825277880337 0.4117457979751333 1.0 0.6013125789757813 7 P51812,Q05655 2 +CBS domain [IPR000644] 0.5316424429430557 0.7946545499202847 0.4268144773667397 1.0 0.6119534462301977 5 Q8NE01,P51790,P51798 3 +C-type lectin-like [IPR001304] 0.708689927583938 0.7532865433381917 0.4512777433862711 1.0 0.6329935866630566 2 Q9UBG0 1 +CD209-like, C-type lectin-like domain [IPR033989] 0.708689927583938 0.7532865433381917 0.4512777433862711 1.0 0.6329935866630566 2 Q9UBG0 1 +ALIX V-shaped domain [IPR025304] 0.7057274522712322 0.741774251739728 0.4582241234001183 1.0 0.6381232684787953 2 Q8WUM4 1 +NOPS [IPR012975] 0.714208977060188 0.7399081629192553 0.4593557209953567 1.0 0.6386411953419457 3 P23246 1 +Survival motor neuron [IPR010304] 0.7050691244239644 0.7392221947665739 0.4597720856764904 1.0 0.638867878829812 2 Q16637 1 +Peptidase M28 [IPR007484] 0.7138623641751605 0.7386405164874003 0.4601253146075899 1.0 0.6390066318504084 3 Q7Z2K6,Q969V3 2 +Glutathione S-transferase, N-terminal [IPR004045] 0.4767592010945922 0.734075728715576 0.4629025851613702 1.0 0.6403951287860535 7 P78417 1 +Fibronectin type II domain [IPR000562] 0.7051483936889498 0.706932457790595 0.4796084522219637 1.0 0.6552397164159223 3 Q9UBV2 1 +Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955] 0.6942067149440434 0.697455452084912 0.4855178089905698 1.0 0.6597391779494703 2 Q15118 1 +Histidine kinase domain [IPR005467] 0.6942067149440434 0.697455452084912 0.4855178089905698 1.0 0.6597391779494703 2 Q15118 1 +OCRE domain [IPR041591] 0.7011976335553154 0.692662970617506 0.4885210823930692 1.0 0.6623925644060863 3 P78332 1 +Fatty acid desaturase domain [IPR005804] 0.6909150757077022 0.684932140160956 0.4933867434774266 1.0 0.6679127037305796 2 O95864 1 +Armadillo repeat-containing domain [IPR006911] 0.6988216919193596 0.6841149639884729 0.4939025733933828 1.0 0.6682523015547808 3 Q9UH62 1 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.6875085274454442 0.6437775093683131 0.5197197199698267 1.0 0.6858434719602124 3 P61289 1 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.6875085274454442 0.6437775093683131 0.5197197199698267 1.0 0.6858434719602124 3 P61289 1 +Tim44-like domain [IPR007379] 0.672481895984186 0.6160624403263176 0.537853310132802 1.0 0.6981297211296585 2 O43615 1 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.5794574542304747 0.5791633086659539 0.5624789857327446 1.0 0.7118225754294308 4 P13674 1 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.6657886071781378 0.5682086876921895 0.5698932730295472 1.0 0.7142651031691902 3 O43823,Q5BKZ1 2 +Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346] 0.6533903884134313 0.5472601291703351 0.5842000316068898 1.0 0.7232952772275779 2 P51784 1 +DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.5654042866671739 0.5265678888751387 0.5984936959831857 1.0 0.7348593482325192 4 P51530 1 +EGF-like calcium-binding domain [IPR001881] 0.6445029624753141 0.5162199165978113 0.605700821436691 1.0 0.7397469596432614 2 O94813 1 +EXPERA domain [IPR033118] 0.6431863067807669 0.511678680442838 0.6088759093784206 1.0 0.7425459591162364 2 Q15125 1 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.648007902535388 0.5084563364862499 0.6111333527631373 1.0 0.7432909045811918 3 P52888,Q99797 2 +CTP synthase, N-terminal [IPR017456] 0.6421988150098763 0.5082827157566613 0.6112550896516225 1.0 0.7432909045811918 2 P17812 1 +CTP synthase GATase domain [IPR033828] 0.6421988150098763 0.5082827157566613 0.6112550896516225 1.0 0.7432909045811918 2 P17812 1 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.4629324546952166 0.4922666050273103 0.6225308847600726 1.0 0.7488644097634792 5 P07437,P04350,P68371,Q9BUF5 4 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.4629324546952166 0.4922666050273103 0.6225308847600726 1.0 0.7488644097634792 5 P07437,P04350,P68371,Q9BUF5 4 +Ricin B, lectin domain [IPR000772] 0.555596468216081 0.4906553050339914 0.6236702632535678 1.0 0.7495586756818574 4 Q10471,Q10472 2 +L27 domain [IPR004172] 0.5509296594697239 0.4738168749135019 0.6356304999480664 1.0 0.7550919080871519 4 Q14168,O14936 2 +L27 domain, C-terminal [IPR014775] 0.5509296594697239 0.4738168749135019 0.6356304999480664 1.0 0.7550919080871519 4 Q14168,O14936 2 +Extended PHD (ePHD) domain [IPR034732] 0.6351401169919408 0.4665677542799357 0.6408091618618088 1.0 0.7573199185639559 3 P55201 1 +Glutathione S-transferase, C-terminal [IPR004046] 0.4039860071847124 0.4571447977375019 0.6475669728843134 1.0 0.7613817741791321 9 P78417 1 +v-SNARE, coiled-coil homology domain [IPR042855] 0.6289101086598504 0.4467327158788886 0.6550680571731262 1.0 0.7655252892381933 3 O75396,O15498 2 +Longin domain [IPR010908] 0.6289101086598504 0.4467327158788886 0.6550680571731262 1.0 0.7655252892381933 3 O75396,O15498 2 +EF hand associated, type-1 [IPR013566] 0.614219881500989 0.4158606263320394 0.6775119925476261 1.0 0.7773818222043279 2 Q8IXI1 1 +EF hand associated, type-2 [IPR013567] 0.614219881500989 0.4158606263320394 0.6775119925476261 1.0 0.7773818222043279 2 Q8IXI1 1 +MIRO domain [IPR020860] 0.614219881500989 0.4158606263320394 0.6775119925476261 1.0 0.7773818222043279 2 Q8IXI1 1 +GYF domain [IPR003169] 0.6129032258064532 0.4117038664623369 0.6805564906789405 1.0 0.7794566164815113 2 O95400 1 +EGF-like domain [IPR000742] 0.5329380764163305 0.410554012186051 0.6813995906969224 1.0 0.7796341608809252 4 Q04721,P07942,O94813 3 +14-3-3 domain [IPR023410] 0.3991430454845158 0.3245130311572731 0.7455496581804859 1.0 0.8180597237704639 6 P27348,P31946,P62258,P63104,Q04917 5 +NIPSNAP [IPR012577] 0.5789993416721473 0.3113686114036472 0.7555204131816688 1.0 0.8255729991525862 2 Q9BPW8 1 +Serine hydroxymethyltransferase-like domain [IPR039429] 0.5757077024358063 0.3023579050934096 0.7623792407149717 1.0 0.8323465130230123 2 P34896 1 +Glutathione S-transferase, C-terminal-like [IPR010987] 0.3449805974761165 0.2796843050140347 0.7797197207555466 1.0 0.8463457242898809 11 P78417 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.5707740646313952 0.278137745258272 0.7809066218963334 1.0 0.8463457242898809 3 P04439 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.5707740646313952 0.278137745258272 0.7809066218963334 1.0 0.8463457242898809 3 P04439 1 +MHC class I-like antigen recognition-like [IPR011161] 0.5707740646313952 0.278137745258272 0.7809066218963334 1.0 0.8463457242898809 3 P04439 1 +Immunoglobulin C1-set [IPR003597] 0.5707740646313952 0.278137745258272 0.7809066218963334 1.0 0.8463457242898809 3 P04439 1 +Immunoglobulin I-set [IPR013098] 0.5552995391705089 0.2496086079939673 0.802890041054916 1.0 0.8660772812405895 2 Q8WX93 1 +S100/CaBP-9k-type, calcium binding, subdomain [IPR013787] 0.5543120473996068 0.2471960724604582 0.8047564847288204 1.0 0.8666990673503208 2 P31949 1 +Small GTP-binding protein domain [IPR005225] 0.2650125923949026 0.239416103095175 0.8107829445803789 1.0 0.8727249621134082 43 Q15907,Q969Q5,P61225,P61026,Q9NR31 5 +Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481] 0.5490454246214632 0.2345527546447525 0.8145558828874022 1.0 0.8752918349561263 2 Q96KP1 1 +Exosome complex component, N-terminal domain [IPR025721] 0.542462146148784 0.2192833533088098 0.8264293284867223 1.0 0.8850338711012797 2 Q13868 1 +Laminin-type EGF domain [IPR002049] 0.5325872284397648 0.1975094055812257 0.8434289218223627 1.0 0.8994197635670185 2 P07942 1 +Laminin, N-terminal [IPR008211] 0.5325872284397648 0.1975094055812257 0.8434289218223627 1.0 0.8994197635670185 2 P07942 1 +Domain of unknown function DUF5600 [IPR040990] 0.5240289664252817 0.1797494517762456 0.8573492687633022 1.0 0.9096486562141556 2 Q9H223 1 +EH domain-containing protein, N-terminal [IPR031692] 0.5240289664252817 0.1797494517762456 0.8573492687633022 1.0 0.9096486562141556 2 Q9H223 1 +CS domain [IPR007052] 0.3420650019157856 0.1594592259959996 0.8733070801678102 1.0 0.9246349522179754 9 Q9P035 1 +eRF1 domain 1/Pelota-like [IPR005140] 0.5046082949308776 0.1433108810697478 0.8860446626858707 1.0 0.9343682794666934 2 Q9BRX2 1 +eRF1 domain 2 [IPR005141] 0.5046082949308776 0.1433108810697478 0.8860446626858707 1.0 0.9343682794666934 2 Q9BRX2 1 +eRF1 domain 3 [IPR005142] 0.5046082949308776 0.1433108810697478 0.8860446626858707 1.0 0.9343682794666934 2 Q9BRX2 1 +Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468] 0.5039499670836096 0.1421697308947871 0.886945940144038 1.0 0.9343682794666934 2 Q9BSJ8 1 +Extended synaptotagmin, C-terminal C2 domain [IPR037752] 0.5039499670836096 0.1421697308947871 0.886945940144038 1.0 0.9343682794666934 2 Q9BSJ8 1 +Extended synaptotagmin, C2B domain [IPR037749] 0.5039499670836096 0.1421697308947871 0.886945940144038 1.0 0.9343682794666934 2 Q9BSJ8 1 +Extended synaptotagmin, C2A domain [IPR037733] 0.5039499670836096 0.1421697308947871 0.886945940144038 1.0 0.9343682794666934 2 Q9BSJ8 1 +Synaptotagmin, SMP domain [IPR039010] 0.5039499670836096 0.1421697308947871 0.886945940144038 1.0 0.9343682794666934 2 Q9BSJ8 1 +Clp ATPase, C-terminal [IPR019489] 0.5019749835418057 0.1387831620577591 0.8896214999434715 1.0 0.936528180144986 2 Q9H078 1 +AP complex, mu/sigma subunit [IPR022775] 0.3473983714647487 0.1295778678010423 0.8969004145321788 1.0 0.942492852270898 6 Q9Y2T2 1 +Domain of unknown function DUF4217 [IPR025313] 0.4957208689927604 0.1284229453454184 0.8978142737427082 1.0 0.9430602242311996 2 Q9NVP1 1 +COMM domain [IPR017920] 0.4944042132982245 0.1263120696399414 0.899484902590991 1.0 0.9440286826194256 2 Q9H0A8 1 +GRAM domain [IPR004182] 0.4972011853802952 0.1176499674887013 0.9063450115088632 1.0 0.9483448800762374 3 Q66K14,Q969T9 2 +Thioredoxin domain [IPR013766] 0.2683689470496647 0.1175619059808458 0.906414790193964 1.0 0.9483448800762374 25 P07237,Q96JJ7,Q9H1E5 3 +RNA polymerase Rpb2, domain 7 [IPR007641] 0.4878209348255453 0.1161215152916007 0.9075562374250016 1.0 0.9483448800762374 2 P30876 1 +RNA polymerase, beta subunit, protrusion [IPR007644] 0.4878209348255453 0.1161215152916007 0.9075562374250016 1.0 0.9483448800762374 2 P30876 1 +RNA polymerase Rpb2, domain 3 [IPR007645] 0.4878209348255453 0.1161215152916007 0.9075562374250016 1.0 0.9483448800762374 2 P30876 1 +RNA polymerase Rpb2, domain 2 [IPR007642] 0.4878209348255453 0.1161215152916007 0.9075562374250016 1.0 0.9483448800762374 2 P30876 1 +DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120] 0.4878209348255453 0.1161215152916007 0.9075562374250016 1.0 0.9483448800762374 2 P30876 1 +Peptidase M41 [IPR000642] 0.4871626069782773 0.1151356422504906 0.9083376093149738 1.0 0.9485827953177488 2 Q96TA2 1 +Heat shock chaperonin-binding [IPR006636] 0.4265480895915682 0.1092616965960962 0.9129949263461564 1.0 0.951869865334852 4 Q9NRR5,P31948,Q9UHD9 3 +Potassium channel tetramerisation-type BTB domain [IPR003131] 0.479262672811062 0.1037707969247223 0.91735124200006 1.0 0.9554702038527207 2 Q96CX2 1 +BRO1 domain [IPR004328] 0.4796624161576428 0.0893022655256237 0.9288416936364196 1.0 0.9648017921544688 3 Q8WUM4 1 +STAT transcription factor, DNA-binding [IPR013801] 0.466754443712971 0.0875020936722851 0.9302724213066218 1.0 0.9650954531202386 2 P42224 1 +STAT transcription factor, all-alpha domain [IPR013800] 0.466754443712971 0.0875020936722851 0.9302724213066218 1.0 0.9650954531202386 2 P42224 1 +STAT transcription factor, protein interaction [IPR013799] 0.466754443712971 0.0875020936722851 0.9302724213066218 1.0 0.9650954531202386 2 P42224 1 +Ribosomal protein S4/S9, N-terminal [IPR001912] 0.4598420013166578 0.0793926070693063 0.9367203487854984 1.0 0.9709859102494974 2 Q9NV31 1 +FAD/NAD(P)-binding domain [IPR023753] 0.3397034596375631 0.0736231312005906 0.9413102650486578 1.0 0.9729444624806208 5 P00390,O95831,P22570,P09622 4 +RuvB-like, AAA-lid domain [IPR041048] 0.4509545753785409 0.0698534742445866 0.9443102847941728 1.0 0.9748467205284094 2 Q9Y230 1 +TIP49, P-loop domain [IPR010339] 0.4509545753785409 0.0698534742445866 0.9443102847941728 1.0 0.9748467205284094 2 Q9Y230 1 +Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.4473337722185671 0.0662447338251204 0.9471829825249392 1.0 0.9774122266480756 2 O15027 1 +Rpn11/EIF3F, C-terminal [IPR024969] 0.4021739130434794 0.0622109983245828 0.9503948040601248 1.0 0.9803254379712208 4 P51665,O00487,Q7L5N1 3 +Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.4560051519719069 0.0571413243604649 0.9544326181020616 1.0 0.9815224862891874 3 Q9BUJ2 1 +Rab-GTPase-TBC domain [IPR000195] 0.3324546952224106 0.0569160432274301 0.954612074381966 1.0 0.9815224862891874 5 Q66K14,Q9BXI6,Q8TC07,Q9Y3P9 4 +Ribosomal protein S5, N-terminal [IPR013810] 0.4282422646477968 0.0497229101535463 0.9603431993759924 1.0 0.9843571822730952 2 P82675 1 +Ribosomal protein S5, C-terminal [IPR005324] 0.4282422646477968 0.0497229101535463 0.9603431993759924 1.0 0.9843571822730952 2 P82675 1 +4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.4495959513029675 0.0495939377783053 0.9604459776412424 1.0 0.9843571822730952 3 P21912 1 +SCP2 sterol-binding domain [IPR003033] 0.4487981560750693 0.0486882486247173 0.9611677410087412 1.0 0.9843571822730952 3 Q6YN16,P51659 2 +Kinesin-associated [IPR032405] 0.426596445029627 0.0484859007866961 0.9613290007686888 1.0 0.9843571822730952 2 Q9NQT8 1 +Kinesin-like KIF1-type [IPR022140] 0.426596445029627 0.0484859007866961 0.9613290007686888 1.0 0.9843571822730952 2 Q9NQT8 1 +SET domain [IPR001214] 0.4471727536003965 0.046865935335276 0.9626200779115296 1.0 0.9848794468530944 3 O96028 1 +PIN domain [IPR002716] 0.3880842659644528 0.026814253373805 0.9786078847576924 1.0 0.9933364513663788 2 Q9Y2L1 1 +Kinesin-like [IPR022164] 0.4267369114257516 0.026497872716296 0.9788602303311456 1.0 0.9933364513663788 3 Q9NQT8,Q9Y3P9 2 +Agenet-like domain [IPR008395] 0.4263152376094926 0.0261255676062418 0.9791571840193568 1.0 0.9933364513663788 3 Q06787 1 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.4263152376094926 0.0261255676062418 0.9791571840193568 1.0 0.9933364513663788 3 Q06787 1 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.4263152376094926 0.0261255676062418 0.9791571840193568 1.0 0.9933364513663788 3 Q06787 1 +Fxr1, tudor domain [IPR041560] 0.4263152376094926 0.0261255676062418 0.9791571840193568 1.0 0.9933364513663788 3 Q06787 1 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.3489137590520104 0.0157328055906912 0.9874475551558533 1.0 1.0 2 P51114 1 +ELMO domain [IPR006816] 0.3466096115865726 0.015322646368728 0.9877747754137742 1.0 1.0 2 Q8IZ81 1 +RNA-binding S4 domain [IPR002942] 0.4089562067830116 0.0123713027484272 0.9901293803222826 1.0 1.0 3 P46781,Q9NV31 2 +PIK-related kinase [IPR014009] 0.3179723502304176 0.0117466039883336 0.9906277815703476 1.0 1.0 2 P42345 1 +FATC domain [IPR003152] 0.3179723502304176 0.0117466039883336 0.9906277815703476 1.0 1.0 2 P42345 1 +PIK-related kinase, FAT [IPR003151] 0.3179723502304176 0.0117466039883336 0.9906277815703476 1.0 1.0 2 P42345 1 +Transcription factor IIS, N-terminal [IPR017923] 0.3166556945358817 0.0116374331846169 0.9907148813154658 1.0 1.0 2 Q96ST2 1 +Lsm14-like, N-terminal [IPR025609] 0.2939433838051376 0.0102802079431563 0.9917977252736232 1.0 1.0 2 Q9BX40 1 +DFDF domain [IPR025762] 0.2939433838051376 0.0102802079431563 0.9917977252736232 1.0 1.0 2 Q9BX40 1 +FDF domain [IPR019050] 0.2939433838051376 0.0102802079431563 0.9917977252736232 1.0 1.0 2 Q9BX40 1 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ef72d8222fc6e553a377bbe75d1f3cf618505114 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "APPL1, BAR domain [IPR037929]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-amylase/branching enzyme, C-terminal all beta [IPR006048]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Armadillo-like helical domain-containing protein 3, C-terminal [IPR013636]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related protein 13, N-terminal [IPR018731]", "Autophagy-related protein 16 domain [IPR013923]", "Autophagy-related, C-terminal [IPR015412]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BET1, SNARE domain [IPR039899]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRCT domain [IPR001357]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF1, PHD domain [IPR042008]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-mannosidase, Ig-fold domain [IPR041625]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCDC93, coiled-coil domain [IPR019159]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not N-terminal domain [IPR007207]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "CNOT4, RNA recognition motif [IPR034261]", "COMM domain [IPR017920]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPL domain [IPR012959]", "CPPED1, metallophosphatase domain [IPR041867]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carboxypeptidase E, carboxypeptidase domain [IPR034232]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centrosomal CEP44 domain [IPR029157]", "Chaperone DnaJ, C-terminal [IPR002939]", "Checkpoint kinase 1, catalytic domain [IPR034670]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Conserved oligomeric Golgi complex, subunit 4 [IPR013167]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cupin-like domain 8 [IPR041667]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "Cytosolic fatty-acid binding [IPR000463]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEP domain [IPR000591]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIX domain [IPR001158]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dehydrogenase, E1 component [IPR001017]", "Deoxycytidylate deaminase domain [IPR035105]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dienelactone hydrolase [IPR002925]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dis3-like cold-shock domain 2 [IPR041505]", "Dishevelled C-terminal [IPR024580]", "Dishevelled protein domain [IPR003351]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4592 [IPR028030]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5595 [IPR040967]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Domain of unknown function DUF775 [IPR008493]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase MIB1/2, zinc finger, ZZ-type [IPR042056]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELK domain [IPR005539]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "EngB-type guanine nucleotide-binding (G) domain [IPR030393]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM3C (ILEI) domain [IPR039475]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FCP1-like phosphatase, C-terminal [IPR015388]", "FCP1-like phosphatase, phosphatase domain [IPR011947]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galactosyltransferase, C-terminal [IPR027791]", "Galactosyltransferase, N-terminal [IPR027995]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-butyrobetaine hydroxylase-like, N-terminal [IPR010376]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 13, N-terminal [IPR004193]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Helical and beta-bridge domain [IPR010643]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "Hypoxia induced protein, domain [IPR007667]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intersectin-2, fifth SH3 domain [IPR035741]", "Intersectin-2, first SH3 domain [IPR035737]", "Intersectin-2, fourth SH3 domain [IPR035740]", "Intersectin-2, second SH3 domain [IPR035738]", "Intersectin-2, third SH3 domain [IPR035739]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KOW [IPR005824]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L1 transposable element, RRM domain [IPR043636]", "L1 transposable element, dsRBD-like domain [IPR035300]", "L1 transposable element, trimerization domain [IPR035301]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipocalin/cytosolic fatty-acid binding domain [IPR000566]", "Liprin-alpha, SAM domain repeat 1 [IPR037620]", "Liprin-alpha, SAM domain repeat 2 [IPR037621]", "Liprin-alpha, SAM domain repeat 3 [IPR037622]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "LysM domain [IPR018392]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MYND-like zinc finger [IPR031615]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "Mannosidase Ig/CBM-like domain [IPR041447]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Mind bomb, SH3 repeat domain [IPR040847]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Morc, S5 domain 2-like [IPR041006]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Myb domain [IPR017930]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase intermediate-associated protein 30 [IPR013857]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NCBP2, RNA recognition motif [IPR034148]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NOT4, modified RING finger, HC subclass (C4C4-type) [IPR039515]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Nck2, SH2 domain [IPR035883]", "Nck2, SH3 domain 1 [IPR035559]", "Nck2, SH3 domain 2 [IPR035560]", "Nck2, SH3 domain 3 [IPR035561]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Notch domain [IPR000800]", "Notch, C-terminal [IPR024600]", "Notch, NOD domain [IPR010660]", "Notch, NODP domain [IPR011656]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear speckle splicing regulatory protein 1, N-terminal [IPR018612]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain [IPR019601]", "P-type ATPase, C-terminal [IPR032630]", "P-type ATPase, N-terminal [IPR032631]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PCNA-associated factor, histone-like domain [IPR031444]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Par3/HAL, N-terminal [IPR021922]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain containing protein 8-like [IPR045217]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Peregrin, ePHD domain [IPR042061]", "Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 3,4-dihydroxylase TPA1/OFD1, N-terminal domain [IPR039558]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein disulfide-isomerase A5, N-terminal TRX-like b domain [IPR041865]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine 5'-phosphate oxidase, putative [IPR011576]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal [IPR019576]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RII binding domain [IPR018459]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab-GTPase-TBC domain [IPR000195]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rabaptin coiled-coil domain [IPR018514]", "Rabaptin, GTPase-Rab5 binding domain [IPR015390]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Radical SAM [IPR007197]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal RNA-processing protein 7, C-terminal domain [IPR024326]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpn11/EIF3F, C-terminal [IPR024969]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rrp7, RRM-like N-terminal domain [IPR040447]", "Rrp7A, RNA recognition motif [IPR034890]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SAS-6 coiled-coil domain [IPR041513]", "SCAN domain [IPR003309]", "SCP2 sterol-binding domain [IPR003033]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm4 [IPR034101]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Sphingolipid delta4-desaturase, N-terminal [IPR013866]", "Spindle assembly abnormal protein 6, N-terminal [IPR032396]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromal interaction molecule 2, SAM domain [IPR037610]", "Stromal interaction molecule, Orai1-activating region [IPR032393]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulfotransferase domain [IPR000863]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Sushi/SCR/CCP domain [IPR000436]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TGS [IPR004095]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TauD/TfdA-like domain [IPR003819]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll-interacting protein, C2 domain [IPR037301]", "Toll-interacting protein, CUE domain [IPR041799]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin epsilon and delta complex protein 1 domain [IPR027996]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glucuronate decarboxylase N-terminal [IPR021761]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Uracil-DNA glycosylase-like [IPR005122]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein 14, C-terminal Fig4-binding domain [IPR021841]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vesicle transport v-SNARE, N-terminal [IPR007705]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZCRB1, RNA recognition motif [IPR034219]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger CCCH domain [IPR041686]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC5", "ANKFY1", "ANKHD1", "ANKLE2", "ANLN", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "APMAP", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL8A", "ARMC10", "ARMCX3", "ARMT1", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATG13", "ATG16L1", "ATG7", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B4GALT1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS3", "BCS1L", "BET1", "BIRC6", "BLM", "BLVRA", "BMS1", "BOP1", "BRD2", "BRIX1", "BROX", "BRPF1", "BSDC1", "BSG", "BTF3", "BUB1", "BUB1B", "BUD23", "BZW1", "BZW2", "C10orf76", "C11orf58", "C1orf35", "C2CD2", "CACYBP", "CAD", "CALM3", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CARM1", "CARS", "CASK", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC88A", "CCDC93", "CCNB1", "CCNB2", "CD2BP2", "CD47", "CDC23", "CDC34", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLTC", "CLUH", "CMBL", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT3", "CNOT4", "CNPY2", "COA3", "COASY", "COG4", "COIL", "COLEC12", "COMMD2", "COMMD4", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX2", "CPD", "CPE", "CPNE1", "CPNE3", "CPNE8", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRKL", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP2", "CTDP1", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CWF19L1", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCTD", "DCTN1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DFFA", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERCC2", "ERCC6L", "ERGIC2", "ERGIC3", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGB1", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPKOW", "GPR89B", "GPRASP2", "GPS1", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2F2", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD2A", "HIKESHI", "HINT3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTRA2", "HUWE1", "IAH1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITSN2", "IVD", "IWS1", "JMJD6", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIAA1211", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L2HGDH", "LAMB1", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8C", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM7", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAGED2", "MAK16", "MAN2B1", "MANBA", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED25", "MEPCE", "METAP1", "METAP2", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MGME1", "MIA2", "MIA3", "MIB1", "MICU1", "MICU2", "MID1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPHOSPH8", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL16", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS10", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA40", "NAA50", "NACC1", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCBP2", "NCK2", "NCKIPSD", "NCL", "NCLN", "NCSTN", "NDC80", "NDUFA10", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F2", "NRBP1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NTHL1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H3", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDXK", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN4", "PINX1", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PUF60", "PUM1", "PUM3", "PWP2", "PXN", "PYCR1", "PYCR2", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCL1", "RCN1", "RCN2", "RDX", "RECQL", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RMND1", "RNASEH2A", "RNF14", "RNF20", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPUSD2", "RRBP1", "RRM1", "RRP12", "RRP7A", "RSF1", "RTCA", "RTF1", "RTN1", "RTN3", "RTN4", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGTA", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A4", "SLC2A1", "SLC37A4", "SLC3A2", "SLC4A1AP", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPEN", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM2", "STIP1", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STRN", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6L", "TAGLN2", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D10A", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDRKH", "TECR", "TEDC1", "TELO2", "TES", "TEX10", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOP1", "THYN1", "TIA1", "TIAL1", "TIMELESS", "TIMM10", "TIMM13", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TKT", "TLCD1", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMLHE", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSR1", "TSTA3", "TTC4", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3C", "UBE4A", "UBE4B", "UBLCP1", "UBQLN2", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UGDH", "UGGT1", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCRC1", "UQCRC2", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VCP", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS16", "VPS18", "VPS29", "VPS37B", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YES1", "YKT6", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF207", "ZNF24", "ZNF281", "ZNF326", "ZNF593", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZYX"], "leading_proteins": ["ACOX3", "AGPAT5", "AIFM1", "AKAP8", "ANKLE2", "AP3M1", "ARMCX3", "ATAD3B", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2C1", "BET1", "BRPF1", "BSG", "CALM3", "CALU", "CASK", "CD2BP2", "CD47", "CERS2", "CETN2", "CIRBP", "CLCN3", "CLCN7", "CLPB", "CNNM3", "COMMD4", "COPS6", "CPE", "CPT2", "CSE1L", "CTPS1", "CYB5B", "DDX18", "DHCR24", "DIS3", "DLD", "DNA2", "DNM1L", "EBP", "EFCAB14", "EHD4", "ELMOD2", "ERAP1", "ERGIC3", "ERLIN1", "ERLIN2", "ERMP1", "ESYT1", "EXOC2", "EXOSC2", "FADS2", "FDXR", "FKBP14", "FKBP1A", "FKBP7", "FKBP9", "FMR1", "FOXRED1", "FUCA2", "FXR1", "GALNT1", "GALNT2", "GM2A", "GPAT4", "GPD2", "GSR", "GSTO1", "GUSB", "HACD3", "HADH", "HLA-A", "HLA-C", "HNRNPAB", "HNRNPF", "HNRNPH2", "HNRNPUL1", "HSD17B4", "HSDL2", "IMP3", "INA", "IPO4", "IPO7", "IPO8", "IPO9", "IWS1", "KCTD12", "KHDRBS3", "KHSRP", "KIF13B", "LAMB1", "LNPEP", "LPCAT1", "LPCAT2", "LPGAT1", "LSM14B", "LTA4H", "MCAT", "MFN1", "MFSD10", "MICU2", "MIPEP", "MPP2", "MRC2", "MRPS5", "MTOR", "NCLN", "NEFL", "NIPSNAP1", "NOTCH2", "NSD2", "NUCB1", "NUCB2", "OLA1", "OPA1", "P4HA1", "P4HB", "PALLD", "PDCD6IP", "PDK1", "PDPR", "PELO", "PGRMC2", "PHB2", "PI4K2A", "PIK3C3", "PITRM1", "POLR2B", "POR", "PRKCD", "PSMD14", "PSMD7", "PSME3", "RAB10", "RAB11B", "RAB24", "RABGAP1", "RAP2B", "RBM6", "RCN2", "RHOT2", "RPS6KA1", "RPS6KA3", "RPS9", "RTN3", "RTN4", "RUVBL2", "S100A11", "SAR1A", "SDF4", "SDHB", "SEC16A", "SEC22B", "SEL1L", "SFPQ", "SHMT1", "SLC18B1", "SLC25A24", "SLC2A1", "SLC37A4", "SLIT2", "SMN1*", "SPNS1", "STARD3", "STAT1", "STIP1", "STOM", "STOML2", "STX12", "STX17", "STX3", "STX5", "STX6", "STX7", "SV2A", "SYNCRIP", "TBC1D10A", "TBC1D15", "TBC1D9B", "THOP1", "TIMM10", "TIMM44", "TIMM8B", "TMED10", "TMED2", "TMED7", "TMPO", "TMX3", "TMX4", "TNPO1", "TRAM1", "TUBB", "TUBB4A", "TUBB4B", "TUBB6", "UBQLN2", "UBQLN4", "UNC119B", "USP11", "VIM", "VTI1B", "WBP2", "XPO5", "XPOT", "YKT6", "YME1L1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAH", "YWHAQ", "YWHAZ", "ZMPSTE24", "ZNF326"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ebb8ddfe226dabe2c5f86ff9cb9b93374451f493 --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Syntaxin [IPR045242]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..c9947555f08ef8097b31e1dc3a4dcad776ef6ebe --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f64919371298e850b2c042a1c1e5af0899f626930390b37825d7a8099e2b0444 +size 183177 diff --git a/interpro_family/advanced/plot_1.png b/interpro_family/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..6885706f5041cfc28c6dc5578a35380242dba511 --- /dev/null +++ b/interpro_family/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b964b6f8ac0c1c9d3e3494c051014ba17a22f24d3c0a364726a5bb0840fd402a +size 178836 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..be0591724ed8b57a3fbe002880304f9928959dbf --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Syntaxin [IPR045242]", "2": "Small GTPase [IPR001806]", "3": "Short-chain dehydrogenase/reductase SDR [IPR002347]", "4": "14-3-3 protein [IPR000308]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..50a36e4cbd73539c2d9e9726f69672e8662539e9 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2f259be728436ba493a2462d0504054095f3cbd7ba56ca23a087a3790fa19f22 +size 137464 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..d2d4aa318ea74097a11165fb8cee8785534e9739 --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c407850962385d0e4c348d644c18bb297cde8afcf1c1af4821d77b7d785dc719 +size 133646 diff --git a/interpro_family/basic/plot_2.png b/interpro_family/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..cef66d15fb5dddf1e866d965adcda6727dc55cee --- /dev/null +++ b/interpro_family/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4956fc4f9b2dc3ab7ac8825d82ab62cd6f7542043581f34b6b02529e6456ac2e +size 140124 diff --git a/interpro_family/basic/plot_3.png b/interpro_family/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..06e9303d73a92202cbf4c63ca9445e8fbd965725 --- /dev/null +++ b/interpro_family/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:88d7a3aeb20b4475f0139ee88cf57d5235e79ca5035216d390cc82e49fe5b08d +size 153022 diff --git a/interpro_family/basic/plot_4.png b/interpro_family/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..426534dd4cc0bed2e2a77ba85faeb55f8c3dc700 --- /dev/null +++ b/interpro_family/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:987f357fc09556628a087644e6647385c78c77f4b851d9c3c99edcb9ba158b8f +size 133420 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..2735454803ee2fd3b0f4a9df603eb24e30f32209 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4444b7515f2b349b7dbcdada5743b4d48699852856f7869aa019da8cc4fe0e98 +size 389906 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..72a5ffc73a718dc20073dd0e8bc866c06e7f674c --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier protein [IPR002067] 7 10 2.309675726394073 0.0209061136524317 5.686893203883495 11.07766990291262 0.8032246115450145 0.31892620527414 3.2338505495684404 1.5403272908315857 1.3918146051602212 0.3274613788058813 0.0060517411544212 1.0 1.0 0.0834574734746242 0.000277756887713 +Syntaxin [IPR045242] 5 8 2.2259115125163853 0.0260201090820995 2.674757281553398 5.815533980582524 0.7134969984167514 0.3462495636510407 1.4434464182805606 1.4295601388514203 1.142372356309129 0.3001529293380739 0.0143571981203825 1.0 1.0 0.290751966651369 0.0003706302782608 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 3 5 2.138097496124056 0.0325088311202219 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0001254368379847 1.0 0.0743799864466655 0.0148625463558957 0.0003311660608568 +Major facilitator superfamily [IPR011701] 4 7 1.9920068453047848 0.0463703068224519 1.900485436893204 4.145631067961165 1.0239318262629833 0.2378354197978781 1.3191273068698348 1.552684909115802 1.329586452483978 0.2573287434106264 0.0605122668557856 1.0 1.0 0.4452488918515388 0.0271057364081029 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..26ada59d18f832d90418f417521e13af68845c99 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 2373, + "title": "Average number of proteins per term", + "value": 1.2777075431942688 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8f429219be38e35a0b270a82d813bb695eceb251 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e1deccfa33a578c99ce3ca2242275d7f5a431553 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,123 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial carrier protein [IPR002067] 0.7127858185929072 2.309675726394073 0.0209061136524317 1.0 0.0992204153944412 10 Q9HC21,Q9UJS0,P05141,P12235,P12236,Q6NUK1,O43808 7 +Syntaxin [IPR045242] 0.7660578515974625 2.2259115125163853 0.0260201090820995 1.0 0.1112535474807605 8 P56962,Q13190,O43752,Q13277,O15400 5 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.8246657077284575 2.138097496124056 0.0325088311202219 1.0 0.1244249294327205 5 Q9NZ08,P09960,Q9UIQ6 3 +Major facilitator superfamily [IPR011701] 0.7243470451214924 1.9920068453047848 0.0463703068224519 1.0 0.1481621785381559 7 Q14728,Q7L0J3,O43826,Q96ES6 4 +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.9960500329163922 1.9540042061308656 0.0507007197634745 1.0 0.1552423329015808 2 Q99595 1 +Haem oxygenase-like [IPR016053] 0.9888084265964436 1.9236635497818748 0.0543967697252369 1.0 0.1609520381022286 2 P09601 1 +Haem oxygenase [IPR002051] 0.9888084265964436 1.9236635497818748 0.0543967697252369 1.0 0.1609520381022286 2 P09601 1 +P-type ATPase [IPR001757] 0.7288478249605723 1.9206876619717992 0.0547710959997362 1.0 0.1614037575705062 6 P16615,Q9HD20,P98194,P05023 4 +Mitochondrial carrier UCP-like [IPR002030] 0.9805793285055936 1.8891238330008375 0.0588752376278596 1.0 0.1679218015515755 2 Q9H2D1 1 +Palmitoyl protein thioesterase [IPR002472] 0.9700460829493052 1.844822199695664 0.0650634069875555 1.0 0.1780801208552125 2 P50897 1 +Transmembrane emp24 domain-containing protein [IPR015720] 0.7540583165544175 1.8242233868434208 0.068118307335379 1.0 0.1824432768700389 5 P49755,Q9Y3B3,Q15363 3 +Cleft lip and palate transmembrane 1 [IPR008429] 0.9605003291639236 1.8045915042330587 0.0711386285052786 1.0 0.1859162615011301 2 Q96KA5 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.9605003291639236 1.8045915042330587 0.0711386285052786 1.0 0.1859162615011301 2 Q96KA5 1 +Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708] 0.9516129032258018 1.767070412534665 0.077216436868762 1.0 0.1958315856878711 2 Q15070 1 +AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752] 0.9423963133640486 1.7280993038359809 0.0839704223021902 1.0 0.2052129887982465 2 O00400 1 +Eukaryotic porin/Tom40 [IPR027246] 0.855480120657689 1.7130918097875782 0.0866956505604754 1.0 0.2088942960030891 4 P45880,P21796 2 +Porin, eukaryotic type [IPR001925] 0.9637800460981216 1.7050038914052876 0.0881936986625246 1.0 0.2111843056772665 3 P45880,P21796 2 +ER lumen protein retaining receptor [IPR000133] 0.9354838709677332 1.6988344285033028 0.0893503846694105 1.0 0.2126037928289353 2 P24390 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.931204739960494 1.6807037934264977 0.0928204634165796 1.0 0.2170920695639799 2 Q9Y487 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.931204739960494 1.6807037934264977 0.0928204634165796 1.0 0.2170920695639799 2 Q9Y487 1 +Peptidase A22B, signal peptide peptidase [IPR007369] 0.9279131007241564 1.666750268377771 0.0955640727863409 1.0 0.2203824535685005 2 Q8TCT9 1 +Presenilin/signal peptide peptidase [IPR006639] 0.9279131007241564 1.666750268377771 0.0955640727863409 1.0 0.2203824535685005 2 Q8TCT9 1 +Small GTPase [IPR001806] 0.439690745651221 1.6308186712167516 0.1029285865092695 1.0 0.2306475520236891 28 Q15907,Q969Q5,P61225,Q96P47,P61026,Q15382,Q9H0U4 7 +Cytochrome P450 [IPR001128] 0.9157340355496928 1.6150762005978998 0.1062941941533663 1.0 0.2348735309472232 2 Q6UW02 1 +Endoplasmic reticulum vesicle transporter [IPR045888] 0.91310072416062 1.6038950996736852 0.10873717716534 1.0 0.2390998866279734 2 Q9Y282 1 +CD36 family [IPR002159] 0.9107965766951946 1.5941095523066142 0.110911499788056 1.0 0.2425741834074258 2 Q8WTV0 1 +Nucleobindin [IPR040250] 0.9075049374588412 1.5801271056052184 0.114077760994391 1.0 0.2475762818175649 2 P80303 1 +Tetraspanin/Peripherin [IPR018499] 0.8749177090190711 1.4415949256462506 0.1494166807858103 1.0 0.2944861197578735 2 O43657 1 +TB2/DP1/HVA22-related protein [IPR004345] 0.8919986829107626 1.4244100715464374 0.1543278004340538 1.0 0.3006731284318634 3 Q6NUK4,Q9H6H4 2 +Polyprenyl synthetase [IPR000092] 0.8676761026991445 1.410811594357241 0.1583001748458961 1.0 0.305443804110441 2 Q5T2R2 1 +Aminopeptidase N-type [IPR034016] 0.8765228844254134 1.3636927728617638 0.1726642796053845 1.0 0.3211068460059385 3 Q9NZ08,Q9UIQ6 2 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.8715837998024313 1.344314478393149 0.1788467156415498 1.0 0.3281573059777858 3 P12236,P12235 2 +Proteasome B-type subunit [IPR023333] 0.5940656521678473 1.339430403216407 0.180430597280949 1.0 0.3298627175251865 7 P28070,P49721 2 +Bcl2-like [IPR002475] 0.8502304147465445 1.3367165433644888 0.1813151797790004 1.0 0.3309699397042832 2 Q9BXK5 1 +Bcl-2 family [IPR026298] 0.8502304147465445 1.3367165433644888 0.1813151797790004 1.0 0.3309699397042832 2 Q9BXK5 1 +Peroxisomal acyl-coenzyme A oxidase [IPR034171] 0.8475971033574727 1.3255444619543282 0.1849906327747317 1.0 0.3352153804085327 2 O15254 1 +Acyl-CoA oxidase [IPR012258] 0.8475971033574727 1.3255444619543282 0.1849906327747317 1.0 0.3352153804085327 2 O15254 1 +Carbohydrate sulfotransferase 8-10 [IPR018011] 0.8443054641211098 1.3115851980136015 0.1896601300143032 1.0 0.3409571882757133 2 Q8NCH0 1 +Small GTPase, Ras-type [IPR020849] 0.8578136926177022 1.290305769359861 0.1969445145404096 1.0 0.3498123750032874 3 P61225 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.8561080013170903 1.2836188120841332 0.1992753641842237 1.0 0.352107549671752 3 Q99733,Q01105 2 +HnRNP R/Q splicing factor [IPR006535] 0.8373930217248196 1.2822947748660996 0.1997392602235645 1.0 0.352402427145367 2 O60506 1 +Ribosomal protein S6 kinase II [IPR016239] 0.8357472021066377 1.275326216878231 0.2021938020269671 1.0 0.3557468670606375 2 P51812 1 +Sulfotransferase [IPR005331] 0.8445834705301194 1.2384659881855449 0.215543325855803 1.0 0.3718815190356768 3 Q8NCH0,Q7LGA3 2 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.8337174843595558 1.1959529674396876 0.2317149134628087 1.0 0.3874978785392847 3 Q9HB40,P10619 2 +Histidine phosphatase superfamily, clade-2 [IPR000560] 0.8303598104136105 1.1828312324028014 0.2368760398968998 1.0 0.392258787631084 3 Q9NPH0 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.8120473996050039 1.1752761628146475 0.2398842479519007 1.0 0.3944874015175749 2 Q5T9A4 1 +Dynamin [IPR022812] 0.8267694017136431 1.168809173180804 0.2424805236913727 1.0 0.3973800295025051 3 O60313 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.8260904708209931 1.166158797888061 0.2435502475886419 1.0 0.3984309163033123 3 Q8NBN3 1 +Acyltransferase ChoActase/COT/CPT [IPR000542] 0.8097432521395419 1.1655850178297382 0.2437822681858401 1.0 0.3984309163033123 2 P23786 1 +YTH domain containing protein [IPR045168] 0.7237332109567032 1.1638283671746936 0.2444935737409221 1.0 0.3988671819972001 4 Q7Z739,Q9Y5A9 2 +Importin beta family [IPR040122] 0.7223437277112824 1.1580131219020475 0.2468586815689817 1.0 0.4009014135324666 4 Q8TEX9,Q92973 2 +Glycoside hydrolase, family 29 [IPR000933] 0.8077682685977624 1.1572843432935744 0.2471562080862368 1.0 0.4009014135324666 2 Q9BTY2 1 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.8077682685977624 1.1572843432935744 0.2471562080862368 1.0 0.4009014135324666 2 Q9BTY2 1 +Peptidase C13, legumain [IPR001096] 0.7998683344305472 1.1241413126344293 0.2609530816372691 1.0 0.4164368949060119 2 Q99538 1 +Basigin-like [IPR043204] 0.7932850559578678 1.0966020382832689 0.2728153960890429 1.0 0.4270388752765823 2 P35613 1 +TAF15/EWS/TLS family [IPR034870] 0.8057293381626542 1.0868757050664826 0.2770917445990357 1.0 0.432306844137746 3 Q92804,P35637 2 +Small GTPase superfamily, SAR1-type [IPR006687] 0.7860434496379042 1.0664028713073912 0.2862415642878089 1.0 0.4388805155300639 2 Q9NR31 1 +Stomatin/HflK/HflC family [IPR001972] 0.7837393021724562 1.0568164287449613 0.290595374952276 1.0 0.4446053028766931 2 P27105 1 +Short-chain dehydrogenase/reductase SDR [IPR002347] 0.4064485425805995 1.0409830422704462 0.2978834185707621 1.0 0.4495990282900385 19 Q53GQ0,Q9Y394,Q9HBH5,Q8NBN7,Q06136,Q3SXM5 6 +Calcium uptake protein 1/2/3 [IPR039800] 0.779131007241599 1.037678234749586 0.299419881274261 1.0 0.4502683005474153 2 Q8IYU8 1 +Prolyl 4-hydroxylase [IPR045054] 0.7613561553653727 0.9643451808247772 0.3348728962745131 1.0 0.4836600017403649 2 P13674 1 +Nonaspanin (TM9SF) [IPR004240] 0.7698386565689708 0.9484846427592418 0.342882787277458 1.0 0.491341095537082 3 Q9HD45,Q99805 2 +Prenylated rab acceptor PRA1 [IPR004895] 0.7541145490453942 0.9347201643851762 0.3499325323187978 1.0 0.4966446765505426 2 O60831 1 +Dephospho-CoA kinase [IPR001977] 0.7468729427254461 0.9052609924789564 0.3653271363638162 1.0 0.5101801553850339 2 Q8WVC6 1 +Mitofusin family [IPR027094] 0.7369980250164592 0.8653830946730866 0.3868285565971101 1.0 0.5277894528075238 2 Q8IWA4 1 +Copper chaperone SCO1/SenC [IPR003782] 0.7366688610928157 0.8640600587543333 0.3875548987868855 1.0 0.5277894528075238 2 O75880 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.7366688610928157 0.8640600587543333 0.3875548987868855 1.0 0.5277894528075238 2 O75880 1 +SCAMP [IPR007273] 0.7339479749752886 0.8128340343710474 0.4163132193686563 1.0 0.5503683952990648 3 O15126,O15127 2 +Chloride channel, voltage gated [IPR001807] 0.7215273206056627 0.8036763394708082 0.4215839221606341 1.0 0.5547177836198425 2 P51790 1 +Erlin1/2 [IPR033294] 0.7100065832784739 0.7584176153194366 0.4482010156936677 1.0 0.576849905268107 2 O94905 1 +Major facilitator, sugar transporter-like [IPR005828] 0.7093482554311825 0.7558509768751153 0.4497385490312877 1.0 0.5783861698863793 2 Q7L0J3 1 +Vacuolar protein-sorting protein Bro1-like [IPR045251] 0.7057274522712322 0.741774251739728 0.4582241234001183 1.0 0.5851154110343124 2 Q8WUM4 1 +Tumour protein D52 [IPR007327] 0.7024358130348926 0.7290370693514409 0.4659789874332349 1.0 0.5897430064955022 2 P55327 1 +E3 ubiquitin-protein ligase, SMURF1 type [IPR024928] 0.6951942067149401 0.7012248933076426 0.4831626769831747 1.0 0.6016074668022992 2 Q96PU5 1 +PDK/BCKDK protein kinase [IPR039028] 0.6942067149440434 0.697455452084912 0.4855178089905698 1.0 0.6041603359908874 2 Q15118 1 +Membrane bound O-acyl transferase, MBOAT [IPR004299] 0.6950938426078226 0.6707554522781675 0.5023763306979943 1.0 0.6160925233831217 3 P35610,Q96N66 2 +Proteasome activator PA28 [IPR009077] 0.6875085274454442 0.6437775093683131 0.5197197199698267 1.0 0.6288782143709362 3 P61289 1 +Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238] 0.6861286584374054 0.6389006375482924 0.5228875732323646 1.0 0.630676330658052 3 Q9Y5J9 1 +Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129] 0.6747860434496203 0.624547568090438 0.532268041061509 1.0 0.6372587022583927 2 Q99735 1 +Transport protein particle (TRAPP) component [IPR007194] 0.6718235681369336 0.6136449498442582 0.5394499733685627 1.0 0.6429506714232041 2 O43617 1 +Protein arginine N-methyltransferase [IPR025799] 0.4827018121910962 0.5763670620783646 0.564367102927088 1.0 0.65907634608562 5 Q6P2P2,O60678,Q99873,Q86X55 4 +Translin family [IPR002848] 0.6606319947333787 0.573030067356967 0.5666243359440433 1.0 0.6597642537758659 2 Q15631 1 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.6657886071781378 0.5682086876921895 0.5698932730295472 1.0 0.6618219158324476 3 O43823,Q5BKZ1 2 +Glutathione Transferase family [IPR040079] 0.417523997178537 0.5282385117200787 0.5973338026885466 1.0 0.6788664338026442 9 Q13505 1 +DNA2/NAM7-like helicase [IPR045055] 0.5654042866671739 0.5265678888751387 0.5984936959831857 1.0 0.6792915991469628 4 P51530 1 +Peptidase M3A/M3B [IPR045090] 0.648007902535388 0.5084563364862499 0.6111333527631373 1.0 0.6864686832670611 3 P52888,Q99797 2 +CTP synthase [IPR004468] 0.6421988150098763 0.5082827157566613 0.6112550896516225 1.0 0.6864686832670611 2 P17812 1 +Tubulin [IPR000217] 0.4629324546952166 0.4922666050273103 0.6225308847600726 1.0 0.6932833869372864 5 P07437,P04350,P68371,Q9BUF5 4 +Beta tubulin [IPR002453] 0.4629324546952163 0.492266605027309 0.6225308847600735 1.0 0.6932833869372864 5 P07437,P04350,P68371,Q9BUF5 4 +Prefoldin beta-like [IPR002777] 0.6227781435154723 0.4433179028995357 0.6575358082032947 1.0 0.7180545204171277 2 O15212 1 +KH domain-containing BBP-like [IPR045071] 0.5359448717418133 0.4209339692116437 0.6738032994169758 1.0 0.727027588874061 4 Q96PU8,O75525 2 +Mitochondrial Rho GTPase [IPR021181] 0.614219881500989 0.4158606263320394 0.6775119925476261 1.0 0.7294627760052254 2 Q8IXI1 1 +Snf7 family [IPR005024] 0.4418451400329508 0.4062432989879647 0.6845638425202292 1.0 0.7317432424777044 5 Q8WUX9,O43633,Q9NZZ3,Q9H444 4 +14-3-3 protein [IPR000308] 0.3991430454845158 0.3245130311572731 0.7455496581804859 1.0 0.7729092786641735 6 P27348,P31946,P62258,P63104,Q04917 5 +Serine hydroxymethyltransferase [IPR001085] 0.5757077024358063 0.3023579050934096 0.7623792407149717 1.0 0.7869186334130612 2 P34896 1 +Prefoldin alpha-like [IPR004127] 0.573403554970377 0.2961317470380574 0.7671294700686104 1.0 0.790446475237869 2 P61758 1 +Cation efflux protein [IPR002524] 0.5503620803159992 0.2376781459614154 0.8121307350005764 1.0 0.8339187512576235 2 Q8NEW0 1 +Kinesin light chain [IPR002151] 0.540157998683346 0.2140808298746996 0.8304840247957836 1.0 0.8509233984630374 2 Q9H0B6 1 +Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237] 0.5375246872942746 0.2082257366831954 0.8350527140184574 1.0 0.8541293492956031 2 Q9UBW8 1 +Flotillin family [IPR027705] 0.5253456221198174 0.1824141890675771 0.8552576913516006 1.0 0.8732902330367246 2 O75955 1 +Calponin/LIMCH1 [IPR001997] 0.5233706385780139 0.1784263187919732 0.8583881815186016 1.0 0.8761097439757599 2 Q15417 1 +Ribosomal protein L37/S30 [IPR010793] 0.4927583936800546 0.1237076768273774 0.9015467331263064 1.0 0.9181847200466632 2 Q9BZE1 1 +DNA-directed RNA polymerase, subunit 2 [IPR015712] 0.4878209348255453 0.1161215152916007 0.9075562374250016 1.0 0.923512414841136 2 P30876 1 +Peptidase, FtsH [IPR005936] 0.4871626069782773 0.1151356422504906 0.9083376093149738 1.0 0.9239113360070436 2 Q96TA2 1 +ADP-ribosylation factor 1-5 [IPR045872] 0.4845292955892054 0.1112520869779234 0.9114164485153172 1.0 0.925852411098822 2 P18085 1 +Prolyl 3-hydroxylase [IPR039575] 0.4812376563528658 0.1065318351879608 0.9151603982909952 1.0 0.929257862706261 2 Q32P28 1 +Ribosomal protein S15 [IPR000589] 0.4739960500329183 0.0966663177595854 0.9229913890579092 1.0 0.9368086254210516 2 P82914 1 +Heterogeneous nuclear ribonucleoprotein C [IPR017347] 0.470375246872945 0.0919975735874823 0.9266999674143748 1.0 0.9401705954144128 2 P07910 1 +Transcription factor STAT [IPR001217] 0.466754443712971 0.0875020936722851 0.9302724213066218 1.0 0.943391647760946 2 P42224 1 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 0.4751399407309701 0.0826203621132352 0.9341534100033808 1.0 0.9453074805705854 3 P04899,P63096 2 +G-protein alpha subunit, group I [IPR001408] 0.4751399407309701 0.0826203621132352 0.9341534100033808 1.0 0.9453074805705854 3 P04899,P63096 2 +Ribosomal protein S4/S9 [IPR022801] 0.4598420013166578 0.0793926070693063 0.9367203487854984 1.0 0.9473706633014258 2 Q9NV31 1 +Small GTPase superfamily, ARF/SAR type [IPR006689] 0.322470207648997 0.0790526987940022 0.9369907066028008 1.0 0.9473706633014258 9 Q9Y6B6,Q9NR31 2 +RuvB-like [IPR027238] 0.4509545753785409 0.0698534742445866 0.9443102847941728 1.0 0.9535524705602436 2 Q9Y230 1 +CPSF6/7 family [IPR034772] 0.437788018433182 0.0574712227999546 0.9541698290869508 1.0 0.9618712848017564 2 Q8N684 1 +Ribosomal protein S5 [IPR000851] 0.4282422646477968 0.0497229101535463 0.9603431993759924 1.0 0.9672726706787904 2 P82675 1 +Exportin-1/5 [IPR045065] 0.4124423963133664 0.0389743737235195 0.9689108198916864 1.0 0.9750743747256028 2 Q9HAV4 1 +Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100] 0.4104674127715626 0.0378000237250285 0.9698471254573104 1.0 0.975496986634112 2 P09622 1 +Clathrin light chain [IPR000996] 0.4098090849242946 0.0374164910544295 0.9701529239176164 1.0 0.975496986634112 2 P09496 1 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.4263152376094926 0.0261255676062418 0.9791571840193568 1.0 0.9833008877181268 3 Q06787 1 +Ribosomal protein L14P [IPR000218] 0.3706385780118523 0.0208043781202553 0.9834017052609794 1.0 0.9871456203825314 2 Q6P1L8 1 +Desmosomal cadherin [IPR009122] 0.3578011849901277 0.0175288092499569 0.9860147499165524 1.0 0.9889319533186725 2 Q14126 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bb5cee44ada19c971864f2ac93f898bc53520b13 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1,4-alpha-glucan-branching enzyme [IPR037439]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S10, mitochondrial [IPR040055]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchor protein 9/Pericentrin [IPR028745]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP12, ATP synthase F1-assembly protein [IPR011419]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 2/3 complex subunit 5 [IPR006789]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Alpha/gamma-adaptin-binding protein p34 [IPR019341]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit [IPR006111]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat-containing protein 6 [IPR040104]", "Armadillo-like helical domain-containing protein 3-like [IPR039868]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arv1 protein [IPR007290]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Ataxin2 [IPR033093]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 13 [IPR040182]", "Autophagy-related protein 16 [IPR045160]", "Autophagy-related protein 9 [IPR007241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BET1-like protein [IPR039897]", "BRCA1-A complex subunit BRE [IPR010358]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Bet3 family [IPR016721]", "Beta tubulin [IPR002453]", "Beta-1,4-galactosyltransferase [IPR003859]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicaudal-D protein [IPR018477]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "Brain acid soluble protein 1 [IPR008408]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT complex, subunit 3/ 5 [IPR012270]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 10 [IPR039740]", "CCR4-NOT transcription complex subunit 4 [IPR039780]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMM domain-containing protein 2 [IPR037354]", "COMM domain-containing protein 4 [IPR037356]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CTD phosphatase Fcp1 [IPR039189]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Carboxymethylenebutenolidase homolog [IPR042946]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein Cenp-K [IPR020993]", "Centromere protein U [IPR025214]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 44kDa [IPR033603]", "Centrosomal protein of 55kDa [IPR038926]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 5 [IPR028727]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 93 [IPR039116]", "Coilin [IPR024822]", "Complex I intermediate-associated protein 30, mitochondrial [IPR039131]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme [IPR000277]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase assembly protein COX14 [IPR029208]", "Cytochrome c oxidase assembly protein CtaG/Cox11 [IPR007533]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic protein NCK [IPR017304]", "Cytoplasmic protein NCK2 [IPR028524]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit RPB6 [IPR028363]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Decaprenyl diphosphate synthase-like [IPR001441]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Deoxycytidylate deaminase [IPR016473]", "Deoxycytidylate deaminase-related [IPR015517]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Dishevelled family [IPR008339]", "Dishevelled-2 [IPR008341]", "Dishevelled-related protein [IPR015506]", "Divalent ion tolerance protein, CutA [IPR004323]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [IPR039485]", "Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase [IPR039487]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELMO domain-containing protein 2 [IPR030724]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 6-like [IPR029008]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongin B [IPR039049]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosulphine [IPR006760]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Essential MCU regulator, mitochondrial [IPR018782]", "Esterase-like [IPR000801]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FUN14 [IPR007014]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Forkhead box protein C1 [IPR033067]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GOSR2/Membrin/Bos1 [IPR027027]", "GPCR-associated sorting protein [IPR043374]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI mannosyltransferase [IPR005599]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GRIP1-associated protein 1 [IPR026204]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "GTP-binding protein, ribosome biogenesis, YsxC [IPR019987]", "Galactokinase [IPR000705]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-glutamyltranspeptidase [IPR000101]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit beta [IPR026873]", "Girdin [IPR027717]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine 6-phosphate N-acetyltransferase [IPR039143]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, ALG6/ALG8 [IPR004856]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HS1-associating protein X-1 [IPR017248]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "Hypoxia-inducible factor 1-alpha inhibitor [IPR027445]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Immunity-related GTPase family Q protein [IPR040070]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 7 [IPR033060]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intersectin-2 [IPR027029]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intracellular lipid binding protein [IPR031259]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Isoamyl acetate-hydrolyzing esterase Iah1-like [IPR045136]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-associated protein 3 [IPR008658]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Ndc80 [IPR005550]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Liprin-alpha-1 [IPR030438]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lupus La protein [IPR002344]", "LysM and putative peptidoglycan-binding domain-containing protein 1-4 [IPR045030]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase phosphoprotein 6 [IPR019324]", "MAP3K12-binding inhibitory protein 1 [IPR026062]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "MT-A70-like [IPR007757]", "Macrophage migration inhibitory factor [IPR001398]", "Magnesium transporter protein 1 [IPR006844]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med24, [IPR021429]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthiotransferase [IPR005839]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microtubule associated protein 1 [IPR026074]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim10 [IPR027100]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit TOM6 homologue [IPR029182]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Multidrug resistance protein 1 [IPR030258]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase Ard1-like [IPR045047]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "N6-adenosine-methyltransferase non-catalytic subunit METTL14-like [IPR045123]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neurogenic locus Notch 2 [IPR022336]", "Neuroplastin [IPR027112]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Not2/Not3/Not5 [IPR040168]", "Notch [IPR008297]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 2 [IPR027157]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear speckle splicing regulatory protein 1 [IPR042816]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "NudC domain-containing protein 1 [IPR037895]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "OPI10 family [IPR031318]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 3 [IPR020795]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Osteopetrosis-associated transmembrane protein 1 precursor [IPR019172]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "P-type ATPase, subfamily IV [IPR006539]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pat1-like [IPR039900]", "Paxillin [IPR001904]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal biogenesis factor 11 [IPR008733]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxisome membrane protein, Pex16 [IPR013919]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol 3-kinase, Vps34 type [IPR008290]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phospholipid-transporting ATPase IG [IPR030363]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphoserine phosphatase [IPR004469]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polycomb protein EED [IPR037352]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Pre-rRNA-processing protein TSR2 [IPR019398]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline racemase family [IPR008794]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase 3 [IPR039839]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LCHN/Anr2 [IPR018626]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein Njmu-R1 [IPR028280]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein SMG8 [IPR028802]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein TFG [IPR033512]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF719 [IPR007998]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein virilizer [IPR026736]", "Protein wntless [IPR009551]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Proton-dependent oligopeptide transporter family [IPR000109]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase, RluC/RluD [IPR006225]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA methyltransferase [IPR003750]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxamine 5'-phosphate oxidase [IPR000659]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAD3/XPD family [IPR001945]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase, Rpb8 [IPR005570]", "RNA polymerase, subunit omega/Rpo6/RPB6 [IPR006110]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding protein Nova-2 [IPR033087]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab-like protein 6 [IPR040385]", "Rab24 [IPR041828]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab9 [IPR041824]", "Rabaptin [IPR003914]", "Rabaptin-5 [IPR029880]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Ran-interacting Mog1 protein [IPR007681]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab-23 [IPR034114]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Respirasome Complex Assembly Factor 1 [IPR010742]", "Reticulon-4-interacting protein 1 [IPR037397]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retinol-binding protein 1 [IPR031264]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease P protein subunit Rpp29/RNP1 [IPR002730]", "Ribonuclease P/MRP subunit Rpp29 [IPR016848]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein 7 [IPR040446]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L16 [IPR000114]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L55, mitochondrial [IPR018615]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S27/S33, mitochondrial [IPR013219]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SERRATE/Ars2 [IPR039727]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SSNA1 family [IPR033362]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saf4/Yju2 protein [IPR007590]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 12 [IPR034477]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase Atg1-like [IPR045269]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small acidic protein [IPR026714]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Sperm-associated antigen 5 [IPR028728]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Sphingolipid delta(4)-desaturase DES1 [IPR031196]", "Sphingolipid delta4-desaturase [IPR011388]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle assembly checkpoint component Mad1 [IPR008672]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor Yju2 [IPR043701]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Stromal interaction molecule [IPR037608]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar phosphate transporter [IPR000849]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntaxin-17 [IPR028676]", "Syntaxin-3 [IPR031186]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex 11 [IPR008862]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TB2/DP1/HVA22-related protein [IPR004345]", "TCF25/Rqc1 [IPR006994]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TRAPP III complex, Trs85 [IPR024420]", "TREX component Tex1/THOC3 [IPR040132]", "Tankyrase 1-binding protein-like [IPR040006]", "Target of Myb protein 1 [IPR014645]", "Taxilin family [IPR026183]", "Telomere-associated protein Rif1 [IPR028566]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcriptional regulator TACO1-like [IPR002876]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 11 [IPR026120]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Transport protein particle (TRAPP) component [IPR007194]", "Transposase, L1 [IPR004244]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Trimethyllysine dioxygenase [IPR012776]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Tropomodulin [IPR004934]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin epsilon and delta complex protein 1 [IPR043535]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronic acid decarboxylase [IPR044516]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "UbiE/COQ5 methyltransferase [IPR004033]", "Ubiquilin-1/2 [IPR028430]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0390 [IPR019034]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Vacuole morphology and inheritance protein 14 [IPR026825]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vasodilator-stimulated phosphoprotein [IPR034367]", "Vasodilator-stimulated phosphoprotein/ENA/VASP-like [IPR017354]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WASH complex subunit 3 [IPR019309]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "Yos1-like [IPR013880]", "ZPR1 family [IPR040141]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC-type and RNA-binding motif-containing protein 1 [IPR044598]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter 9 [IPR040177]", "Zinc transporter Msc2-like [IPR045316]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA export factor Gle2/RAE1 [IPR037631]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein RRP36 [IPR009292]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-specific 2-thiouridylase [IPR004506]"], "available_proteins": ["AAAS", "AAGAB", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABHD12", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1S1", "ALDH18A1", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG8", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANKLE2", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "API5", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFIP1", "ARFIP2", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC1", "ARMC6", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG13", "ATG16L1", "ATG7", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATXN2", "ATXN2L", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BANF1", "BASP1", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL2L13", "BCLAF1", "BDH2", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BUB1", "BUB1B", "BUD23", "BUD31", "BYSL", "C10orf76", "C11orf58", "C12orf43", "C12orf73", "C14orf2", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C20orf24", "C2CD2", "C2orf49", "C5orf15", "C5orf24", "C8orf33", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CAST", "CBR1", "CBX3", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCDC88A", "CCDC93", "CCDC94", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC37", "CDC40", "CDC42", "CDC45", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CDV3", "CEBPZ", "CELF2", "CENPK", "CENPU", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD5", "CHD8", "CHERP", "CHMP1A", "CHMP2A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST12", "CHST14", "CIAPIN1", "CIP2A", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COIL", "COLGALT1", "COMMD2", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP2", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTD", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEGS1", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2B1", "EIF2B2", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP2", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERCC2", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM162A", "FAM177A1", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTB", "FOXC1", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCAT", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMFB", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNL1", "GNL2", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPX8", "GRIPAP1", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HTT", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IGBP1", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS7", "IPO4", "IPO5", "IRGQ", "IRS4", "ISCU", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFAP3", "KIFBP", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L3HYPDH", "LAMP1", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMF2", "LNPEP", "LONP1", "LPCAT3", "LRPAP1", "LRPPRC", "LRRC47", "LSM12", "LSM2", "LSM3", "LSM4", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD1L1", "MAGED2", "MAGT1", "MAK16", "MAN1A2", "MAP1B", "MAP1S", "MAP4", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAVS", "MBD3", "MBIP", "MBOAT7", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MED24", "MED25", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL14", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORF4L1", "MORF4L2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL55", "MRPL9", "MRPS10", "MRPS11", "MRPS14", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTR", "MTX1", "MTX2", "MXRA7", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCK2", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA13", "NDUFA4", "NDUFAF1", "NDUFAF3", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NF1", "NFS1", "NHP2", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F2", "NRM", "NSA2", "NSF", "NSMCE2", "NSRP1", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OSTM1", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PAWR", "PBDC1", "PBRM1", "PC", "PCBD1", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDSS1", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PES1", "PEX11A", "PEX14", "PEX16", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPO", "PNPT1", "POFUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PSPH", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM3", "PURA", "PWP2", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTB", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM5", "RBM6", "RBM8A", "RBP1", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF40", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SCRN3", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN4", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC15A4", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMDT1", "SMG8", "SMIM12", "SMPD4", "SMU1", "SNAPIN", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF12", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG2", "STARD3", "STAT1", "STAT3", "STIM2", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARS", "TARS2", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TCP11L1", "TECR", "TEDC1", "TEFM", "TES", "TEX10", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TK1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM33", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMLHE", "TMOD3", "TMX2", "TNKS1BP1", "TNPO1", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM6", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP2", "TPT1", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSFM", "TSN", "TSNAX", "TSPAN10", "TSPAN6", "TSR1", "TSR2", "TSTA3", "TTC19", "TTC26", "TTC37", "TTC38", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE3C", "UBE4A", "UBE4B", "UBQLN2", "UBR4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNG", "UPF1", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRQ", "UROD", "USMG5", "USP10", "USP14", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4B", "VPS51", "VPS53", "VTA1", "WAPL", "WARS", "WASHC3", "WBP11", "WBP2", "WDR12", "WDR18", "WDR41", "WDR46", "WDR74", "WDR82", "WDR91", "WFS1", "WIPI2", "WLS", "WTAP", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YEATS4", "YIF1A", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", 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+size 137067 diff --git a/interpro_homologous_superfamily/basic/plot_8.png b/interpro_homologous_superfamily/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..05df0b3e49a1515630c58f280df97f0c4e8e0016 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a1e2c76bdceceaf981d6bb78b413e07bd1cfa589dadb247a8a4b070bd716334d +size 146416 diff --git a/interpro_homologous_superfamily/basic/plot_9.png b/interpro_homologous_superfamily/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..c62541de8cecdd3b969714587a71eadb6870ea4f --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:27dcb138f65f51cc1a3b8614f024aa98b4be4ff25440f8ab0b978fcd5be8c0ce +size 145027 diff --git a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0340c91cd5cf68eec0fcd558440cc3454ba868b7 --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:301537e33f7f255d72bf5c696a79216702472c4dc67015039b5ed6caa3fb9449 +size 144738 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..14840990f1d71db1cb233c7901cca3acb57e0973 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,8 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier domain superfamily [IPR023395] 12 20 3.470728348998588 0.0005190488078605 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 9.51244309544461e-08 0.0142466262053111 2.8899483668534896e-05 2.19272845709178e-07 1.2929972163241432e-08 +SNARE [IPR010989] 7 9 2.573487078306513 0.0100679406308936 2.4854368932038833 5.364077669902913 0.7966086592831925 0.3585374753437345 1.5079985943563208 1.7302199405020957 1.098385457365192 0.3157194502762394 0.0208873878301334 1.0 1.0 0.3247468214281712 4.818994730788961e-06 +Alpha/Beta hydrolase fold [IPR029058] 11 22 2.53856732376996 0.011130738491885 7.793689320388349 25.487864077669904 0.3803730368869525 0.1931612116461074 2.8504230618688027 2.5849355029363217 1.9090082785106757 0.2379814650369476 0.0036285024863201 0.0410390344011431 0.0004462949229121 0.0011340341959979 0.0013809720441502 +Glycoside hydrolase superfamily [IPR017853] 8 17 2.2908298431387237 0.021973256890283 7.094660194174757 15.565533980582524 0.5992585613623983 0.1928722204186086 2.565315823223627 1.245604487832095 1.9386029676344616 0.2695693578719223 0.0003422426455392 1.0 1.0 0.1300982938321277 0.000181120869522 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 3 5 2.138097496124056 0.0325088311202219 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 0.0002190493099042 1.0 0.0832836732680532 0.0188064524051028 0.0005732271800539 +Peptidase M4/M1, CTD superfamily [IPR027268] 3 5 2.138097496124056 0.0325088311202219 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 0.0002190493099042 1.0 0.0832836732680532 0.0188064524051028 0.0005732271800539 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 2 6 1.9622407626612277 0.049734460230614 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0091783194539023 0.0561990347849709 0.1094892401774078 0.0328731354880699 0.0181181417645757 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..838e1eb603ded310120462521ffac773f0d64183 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 956, + "title": "Average number of proteins per term", + "value": 4.645397489539749 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..82108f4ec26fc8d020cec786511bc74750274c4c --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d3d7e4a08bff152bb85b1b9dd43aa4081874db40 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,108 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial carrier domain superfamily [IPR023395] 0.7498883504613915 3.4707283489985876 0.0005190488078605 0.3912450563724451 0.1302731185101849 20 Q9BSK2,Q9HC21,P05141,Q9NZJ7,P12235,P12236,Q6NUK1,Q9Y619,Q9H2D1,Q9Y6C9,Q9UBX3,Q70HW3 12 +SNARE [IPR010989] 0.8024838385241142 2.573487078306513 0.0100679406308936 0.9999370852953626 0.1302731185101849 9 P56962,O15400,O14653,O43752,Q13277,Q9UEU0,Q13190 7 +Alpha/Beta hydrolase fold [IPR029058] 0.5903498642913225 2.53856732376996 0.011130738491885 0.999977469715254 0.1302731185101849 22 Q4J6C6,Q9HB40,Q8NCC3,Q8NCG7,P07099,Q9NUJ1,Q9H6V9,P10619,Q9H3G5,P50897,Q9UMR5 11 +Glycoside hydrolase superfamily [IPR017853] 0.5936552243571204 2.2908298431387233 0.021973256890283 0.9999999994039288 0.1615879506700816 17 P06280,P16278,P10253,P04062,P06865,Q9BTY2,P08236,P54802 8 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.8246657077284575 2.138097496124056 0.0325088311202219 0.999999999999981 0.1964057327673537 5 Q9NZ08,P09960,Q9UIQ6 3 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.8246657077284575 2.138097496124056 0.0325088311202219 0.999999999999981 0.1964057327673537 5 Q9NZ08,P09960,Q9UIQ6 3 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.7376110304708573 1.9622407626612273 0.049734460230614 1.0 0.2459608810323282 6 O43169,O15173 2 +Immunoglobulin-like domain superfamily [IPR036179] 0.6747728879662407 1.931689330184856 0.0533978625090136 1.0 0.247956235027669 9 P10321,P35613,P04439,Q08722 4 +Haem oxygenase-like, multi-helical [IPR016084] 0.9888084265964436 1.9236635497818748 0.0543967697252369 1.0 0.247956235027669 2 P09601 1 +P-type ATPase, A domain superfamily [IPR008250] 0.7288478249605723 1.9206876619717992 0.0547710959997362 1.0 0.247956235027669 6 P16615,Q9HD20,P98194,P05023 4 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.7288478249605723 1.9206876619717992 0.0547710959997362 1.0 0.247956235027669 6 P16615,Q9HD20,P98194,P05023 4 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.7288478249605723 1.9206876619717992 0.0547710959997362 1.0 0.247956235027669 6 P16615,Q9HD20,P98194,P05023 4 +MFS transporter superfamily [IPR036259] 0.5663631970395998 1.872236148497734 0.0611739400705091 1.0 0.2646257317077228 13 Q14728,Q96ES6,Q7L0J3,O00400,Q99808 5 +Band 7/SPFH domain superfamily [IPR036013] 0.6634007185640727 1.72110799654933 0.0852312284978153 1.0 0.3207915529287855 8 Q99623,O75477,Q9UJZ1,P27105,O94905 5 +Porin domain superfamily [IPR023614] 0.855480120657689 1.7130918097875782 0.0866956505604754 1.0 0.3237540700617756 4 P45880,P21796 2 +Alkaline-phosphatase-like, core domain superfamily [IPR017850] 0.93778801843318 1.7085926581304471 0.087526429577414 1.0 0.3253425766080666 2 Q5H8A4 1 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.9364713627386372 1.703016916117195 0.0885649027595625 1.0 0.3253425766080666 2 A6NIH7 1 +Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261] 0.9321922317314024 1.684888705552279 0.0920100460675372 1.0 0.3280127164091852 2 P16435 1 +Riboflavin synthase-like beta-barrel [IPR017938] 0.9321922317314024 1.684888705552279 0.0920100460675372 1.0 0.3280127164091852 2 P16435 1 +Cytochrome P450 superfamily [IPR036396] 0.9157340355496928 1.6150762005978998 0.1062941941533663 1.0 0.3468165515720759 2 Q6UW02 1 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.635929756946517 1.5531858631748496 0.1203787376673555 1.0 0.3773563499552426 7 Q5JRX3 1 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.4584247487007197 1.472909581956068 0.1407754180088911 1.0 0.4140963065123075 20 Q14534,Q8NCN5,Q96CU9,Q6NUM9,Q16134,Q9UHG3,Q8NB78,Q9H9P8,P43304 9 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.8749177090190711 1.4415949256462506 0.1494166807858103 1.0 0.4328555964582871 2 O43657 1 +Tim10-like domain superfamily [IPR035427] 0.7823465317840146 1.409312144671934 0.158742889280623 1.0 0.448416463073084 4 P62072,Q9Y5J9 2 +EF-hand domain pair [IPR011992] 0.3674986939304515 1.376187980908215 0.1687634422084931 1.0 0.4583461669071575 51 Q9H8M7,O95302,Q02818,Q8NF37,P41208,Q9BPX6,P80303,Q14257,Q9Y680,Q6NUK1,Q9NWM8,O75071,P0DP25,O43852,Q8IYU8,Q9UJS0,Q9BRK5,O95202,P43304 19 +START-like domain superfamily [IPR023393] 0.773104539979047 1.3706464182554363 0.1704852054525081 1.0 0.459109454683374 4 Q14849 1 +Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407] 0.8495720868992765 1.333923155358873 0.1822290420107239 1.0 0.4759862408804702 2 Q9UEU0 1 +GOLD domain superfamily [IPR036598] 0.7584748500220124 1.3093774005073644 0.1904065428672139 1.0 0.4824283639570191 4 Q9Y3B3,Q15363 2 +Regulatory factor, effector binding domain superfamily [IPR011256] 0.8423304805793034 1.303213015327417 0.1925020478890076 1.0 0.4824283639570191 2 Q9Y6I9 1 +NAP-like superfamily [IPR037231] 0.8561080013170903 1.2836188120841332 0.1992753641842237 1.0 0.4884801234874818 3 Q99733,Q01105 2 +Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035] 0.7498785141491233 1.273355699780489 0.202891849827612 1.0 0.4948076745795843 4 Q9NP80 1 +LEM/LEM-like domain superfamily [IPR011015] 0.5916100941755201 1.2491996850246008 0.2115920471821648 1.0 0.5076344549107951 6 Q86XL3,P42167 2 +Bcl-2-like superfamily [IPR036834] 0.846021476909893 1.2440969858579565 0.2134638702536446 1.0 0.5076344549107951 3 Q9BXK5 1 +Isoprenoid synthase domain superfamily [IPR008949] 0.843595653605529 1.2345984459898582 0.2169799876570557 1.0 0.5076344549107951 3 P14324,Q5T2R2 2 +Glycosyl hydrolase, all-beta [IPR013780] 0.566808371214003 1.2226645575159345 0.2214564188094874 1.0 0.5119607280096704 8 P04066,Q9BTY2,P06280,P10253 4 +Choline/Carnitine o-acyltransferase, domain 2 [IPR042231] 0.8097432521395419 1.1655850178297382 0.2437822681858401 1.0 0.538797995415266 2 P23786 1 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.5747811957815294 1.164955101720308 0.2440371673795085 1.0 0.538797995415266 6 Q8IXJ6,Q13423,A1L0T0 3 +TGS-like [IPR012676] 0.5659462380894109 1.1206781020253926 0.2624249065706978 1.0 0.5612487934711121 6 Q9NTK5 1 +Beta-hexosaminidase-like, domain 2 [IPR029018] 0.806454437653243 1.0896914614228026 0.2758490786348684 1.0 0.5682128021052876 3 P06865 1 +Peptidase S1, PA clan [IPR009003] 0.7896642527978786 1.081489497484929 0.2794794299817829 1.0 0.5714331616972005 2 Q7KZN9 1 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.6925246366687309 1.0335393979664125 0.3013515430708513 1.0 0.5876705524860898 4 P42892 1 +Beta-grasp domain superfamily [IPR012675] 0.534833017700332 1.03312632597415 0.3015447848485733 1.0 0.5876705524860898 7 Q9BW92,Q9NTK5 2 +HAD-like superfamily [IPR036412] 0.399183085563659 0.9850615532096524 0.3245938369422918 1.0 0.6105913047719985 19 P98194,Q9H857,Q3ZCQ8,P20020,P16615,Q9HD20,P05023,Q969T7 8 +HAD superfamily [IPR023214] 0.399183085563659 0.9850615532096524 0.3245938369422918 1.0 0.6105913047719985 19 P98194,Q9H857,Q3ZCQ8,P20020,P16615,Q9HD20,P05023,Q969T7 8 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.4089857837663845 0.9843473859634128 0.3249447380270132 1.0 0.6105913047719985 17 Q9NR50,Q10472,P46976,O43909,Q10471,P15291 6 +Ricin B-like lectins [IPR035992] 0.7744484688837573 0.96613312713845 0.3339775699542768 1.0 0.6127815683220978 3 Q10471,Q10472 2 +Histidine phosphatase superfamily [IPR029033] 0.5325159762496049 0.9532831971685768 0.3404466026246187 1.0 0.6161864744932994 6 Q9NPH0 1 +FAD-binding, type PCMH, subdomain 2 [IPR016169] 0.7551020408162946 0.9387504906198344 0.3478588636305602 1.0 0.6161864744932994 2 Q15392 1 +FAD-binding, type PCMH-like superfamily [IPR036318] 0.7551020408162946 0.9387504906198344 0.3478588636305602 1.0 0.6161864744932994 2 Q15392 1 +Beta-Galactosidase/glucuronidase domain superfamily [IPR036156] 0.7534562211981355 0.932034990706798 0.3513184426021958 1.0 0.6161864744932994 2 P08236 1 +Acyl transferase domain superfamily [IPR001227] 0.7314022383146664 0.8429492735141532 0.3992568144029624 1.0 0.6393459205514775 2 Q8IVS2 1 +Malonyl-CoA ACP transacylase, ACP-binding [IPR016036] 0.7314022383146664 0.8429492735141532 0.3992568144029624 1.0 0.6393459205514775 2 Q8IVS2 1 +Carboxypeptidase-like, regulatory domain superfamily [IPR008969] 0.7300855826201459 0.8376889984927226 0.4022053938004997 1.0 0.639780959190146 2 P16870 1 +Chloride channel, core [IPR014743] 0.7215273206056627 0.8036763394708082 0.4215839221606341 1.0 0.6467657993643201 2 P51790 1 +C-type lectin fold [IPR016187] 0.708689927583938 0.7532865433381917 0.4512777433862711 1.0 0.6629070240678391 2 Q9UBG0 1 +C-type lectin-like/link domain superfamily [IPR016186] 0.708689927583938 0.7532865433381917 0.4512777433862711 1.0 0.6629070240678391 2 Q9UBG0 1 +Kringle-like fold [IPR013806] 0.7051483936889498 0.706932457790595 0.4796084522219637 1.0 0.6741352619552314 3 Q9UBV2 1 +Fibronectin type II domain superfamily [IPR036943] 0.7051483936889498 0.706932457790595 0.4796084522219637 1.0 0.6741352619552314 3 Q9UBV2 1 +Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784] 0.6942067149440434 0.697455452084912 0.4855178089905698 1.0 0.6775985772189559 2 Q15118 1 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.3734838625585177 0.6849623424752356 0.4933676842600021 1.0 0.684556612703283 16 Q13505,P78417 2 +Proteasome activator superfamily [IPR036252] 0.6875085274454442 0.6437775093683131 0.5197197199698267 1.0 0.6991270511643013 3 P61289 1 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.6875085274454442 0.6437775093683131 0.5197197199698267 1.0 0.6991270511643013 3 P61289 1 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.6875085274454442 0.6437775093683131 0.5197197199698267 1.0 0.6991270511643013 3 P61289 1 +Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352] 0.6747860434496203 0.624547568090438 0.532268041061509 1.0 0.7080594977507996 2 Q99735 1 +NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096] 0.6718235681369336 0.6136449498442582 0.5394499733685627 1.0 0.7123123957739584 2 O43617 1 +Translin, N-terminal [IPR016068] 0.6606319947333787 0.573030067356967 0.5666243359440433 1.0 0.7237995027825382 2 Q15631 1 +Translin superfamily [IPR036081] 0.6606319947333787 0.573030067356967 0.5666243359440433 1.0 0.7237995027825382 2 Q15631 1 +Translin, C-terminal [IPR016069] 0.6606319947333787 0.573030067356967 0.5666243359440433 1.0 0.7237995027825382 2 Q15631 1 +Prefoldin [IPR009053] 0.5737812911725955 0.557767292759017 0.5770032996919809 1.0 0.7279860768732473 4 Q9UHV9,P61758,O15212 3 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.6477946017116538 0.527638568141818 0.5977502186633676 1.0 0.7433621045875513 2 P52888 1 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.648007902535388 0.5084563364862499 0.6111333527631373 1.0 0.7548365442397406 3 P52888,Q99797 2 +p53-like tetramerisation domain superfamily [IPR036674] 0.6375905200790007 0.4925495883195018 0.622330875506028 1.0 0.7621662473860291 2 P04637 1 +Tubulin, C-terminal [IPR023123] 0.4629324546952166 0.4922666050273103 0.6225308847600726 1.0 0.7621662473860291 5 P07437,P04350,P68371,Q9BUF5 4 +Tubulin/FtsZ, C-terminal [IPR008280] 0.4629324546952166 0.4922666050273103 0.6225308847600726 1.0 0.7621662473860291 5 P07437,P04350,P68371,Q9BUF5 4 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.4629324546952166 0.4922666050273103 0.6225308847600726 1.0 0.7621662473860291 5 P07437,P04350,P68371,Q9BUF5 4 +L27 domain superfamily [IPR036892] 0.5509296594697239 0.4738168749135019 0.6356304999480664 1.0 0.7691933644941159 4 Q14168,O14936 2 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.2605248188794065 0.4415187075325781 0.6588375212263395 1.0 0.7870350970246681 82 Q6DKK2,O75718,Q96BR5,Q9UJX2,Q9UBV2,O75153,O00231,Q9Y262,Q15006,Q13217,Q96DB5,Q92791,O14579,P13674,Q5R3I4,Q6ZXV5,O76024,P42345,O15460,O15091,Q9UJX3,Q96TC7,Q9Y5A7,P49321,P50542 25 +14-3-3 domain superfamily [IPR036815] 0.3991430454845158 0.3245130311572731 0.7455496581804859 1.0 0.8474975900363193 6 P27348,P31946,P62258,P63104,Q04917 5 +Dimeric alpha-beta barrel [IPR011008] 0.5789993416721473 0.3113686114036472 0.7555204131816688 1.0 0.8567942052214418 2 Q9BPW8 1 +Galactose mutarotase-like domain superfamily [IPR011013] 0.5815647101479429 0.306946510870999 0.7588840861708761 1.0 0.8595890833878643 3 P10253 1 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.5707740646313952 0.278137745258272 0.7809066218963334 1.0 0.8741973354329642 3 P04439 1 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.5707740646313952 0.278137745258272 0.7809066218963334 1.0 0.8741973354329642 3 P04439 1 +Cation efflux transmembrane domain superfamily [IPR027469] 0.5503620803159992 0.2376781459614154 0.8121307350005764 1.0 0.8975687660815619 2 Q8NEW0 1 +Cyclic phosphodiesterase [IPR009097] 0.5371955233706405 0.207500668344211 0.8356188707677061 1.0 0.91716606251886 2 P09543 1 +Death-like domain superfamily [IPR011029] 0.5299539170506932 0.1919343998986297 0.8477935911384771 1.0 0.9252176633885664 2 Q7Z434 1 +ESCRT assembly domain [IPR037202] 0.5062541145490473 0.1461906794105598 0.8837708632650394 1.0 0.9568345926176416 2 Q9H9H4 1 +eRF1, domain 2 superfamily [IPR042226] 0.5046082949308776 0.1433108810697478 0.8860446626858707 1.0 0.9580958311082688 2 Q9BRX2 1 +RNA polymerase Rpb2, domain 2 superfamily [IPR037034] 0.4878209348255453 0.1161215152916007 0.9075562374250016 1.0 0.971431070669955 2 P30876 1 +DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033] 0.4878209348255453 0.1161215152916007 0.9075562374250016 1.0 0.971431070669955 2 P30876 1 +RNA polymerase Rpb2, OB-fold [IPR014724] 0.4878209348255453 0.1161215152916007 0.9075562374250016 1.0 0.971431070669955 2 P30876 1 +Peptidase M41-like [IPR037219] 0.4871626069782773 0.1151356422504906 0.9083376093149738 1.0 0.971431070669955 2 Q96TA2 1 +BRO1 domain superfamily [IPR038499] 0.4796624161576428 0.0893022655256237 0.9288416936364196 1.0 0.9848547341450424 3 Q8WUM4 1 +Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039] 0.4674127715602391 0.0883066662723257 0.9296329407379428 1.0 0.9848547341450424 2 P35269 1 +STAT transcription factor, N-terminal domain superfamily [IPR036535] 0.466754443712971 0.0875020936722851 0.9302724213066218 1.0 0.9848547341450424 2 P42224 1 +STAT transcription factor, DNA-binding, N-terminal [IPR012345] 0.466754443712971 0.0875020936722851 0.9302724213066218 1.0 0.9848547341450424 2 P42224 1 +STAT transcription factor, coiled coil [IPR015988] 0.466754443712971 0.0875020936722851 0.9302724213066218 1.0 0.9848547341450424 2 P42224 1 +G protein alpha subunit, helical insertion [IPR011025] 0.4751399407309701 0.0826203621132352 0.9341534100033808 1.0 0.9853917356610996 3 P04899,P63096 2 +RNA-binding S4 domain superfamily [IPR036986] 0.4090909090909141 0.0746465858918525 0.9404959073106698 1.0 0.9882290876101212 4 P46781,Q9Y2Z4,Q9NV31 3 +p53-like transcription factor, DNA-binding [IPR008967] 0.4669081330260134 0.0711102772291376 0.9433099888332426 1.0 0.988784920332124 3 P42224,P04637 2 +RuvBL1/2, DNA/RNA binding domain [IPR042487] 0.4509545753785409 0.0698534742445866 0.9443102847941728 1.0 0.988784920332124 2 Q9Y230 1 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.2697874460787712 0.0584949117390414 0.9533544154008065 1.0 0.992060434197042 19 Q9UJ14,P28070,P49721 3 +Rab-GTPase-TBC domain superfamily [IPR035969] 0.3324546952224106 0.0569160432274301 0.954612074381966 1.0 0.992060434197042 5 Q66K14,Q9BXI6,Q8TC07,Q9Y3P9 4 +SCP2 sterol-binding domain superfamily [IPR036527] 0.4487981560750693 0.0486882486247173 0.9611677410087412 1.0 0.995532351467342 3 Q6YN16,P51659 2 +HotDog domain superfamily [IPR029069] 0.3149917627677148 0.0209492655434518 0.9832861270127116 1.0 1.0 5 Q9Y305,O14734,O00154,P51659 4 +Ribosomal protein L14 superfamily [IPR036853] 0.3706385780118523 0.0208043781202553 0.9834017052609794 1.0 1.0 2 Q6P1L8 1 +ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034] 0.3406846609611612 0.0143632616569022 0.988540169315994 1.0 1.0 2 P06576 1 +Signal recognition particle, SRP9/SRP14 subunit [IPR009018] 0.2695852534562241 0.0095850586079279 0.9923523468251072 1.0 1.0 2 P49458 1 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..259dfaa19f662fcc06dc485c91d72eba846701d6 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP12 orthogonal Bundle domain superfamily [IPR023335]", "ATP12, ATP synthase F1-assembly protein, N-terminal [IPR042272]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Actin-related protein 2/3 complex subunit 5 superfamily [IPR036743]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Calycin [IPR012674]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily [IPR023471]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DIX domain superfamily [IPR038207]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Decaprenyl diphosphate synthase-like superfamily [IPR036424]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GBBH-like, N-terminal domain superfamily [IPR038492]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-glutamyltranspeptidase, large subunit, C-terminal domain [IPR043138]", "Gamma-glutamyltranspeptidase, small subunit [IPR043137]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hypoxia-inducible factor 1-alpha inhibitor, domain II [IPR027452]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrase-like, N-terminal [IPR017856]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L1 transposable element, C-terminal domain [IPR042566]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lamin tail domain superfamily [IPR036415]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "LysM domain superfamily [IPR036779]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MAP kinase activated protein kinase, C-terminal [IPR027442]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "Mitochondrial ribosomal protein L55 superfamily [IPR044884]", "MoaB/Mog-like domain superfamily [IPR036425]", "Moesin tail domain superfamily [IPR008954]", "Mog1/PsbP, alpha/beta/alpha sandwich [IPR016123]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Ndc80 domain superfamily [IPR038273]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Notch-like domain superfamily [IPR035993]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPB6/omega subunit-like superfamily [IPR036161]", "RUN domain superfamily [IPR037213]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease P/MRP subunit Rpp29 superfamily [IPR036980]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rof/RNase P-like [IPR023534]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAS-6, N-terminal domain superfamily [IPR038558]", "SCAN domain superfamily [IPR038269]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "Sushi/SCR/CCP superfamily [IPR035976]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Taurine dioxygenase TauD-like superfamily [IPR042098]", "Tautomerase/MIF superfamily [IPR014347]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transcriptional regulator TACO1-like, domain 3 [IPR026564]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPA domain superfamily [IPR037129]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YebC-like [IPR029072]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC5", "ANAPC7", "ANKFY1", "ANKHD1", "ANKLE2", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL8A", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATG13", "ATG16L1", "ATG7", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATPAF2", "ATXN10", "ATXN2", "AURKA", "B4GALT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAS3", "BCL2L12", "BCL2L13", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOP1", "BRD2", "BROX", "BRPF1", "BSDC1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C10orf76", "C1QBP", "C2CD2", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC88A", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD47", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP170", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHRAC1", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPE", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF2", "CSTF3", "CTBP2", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUTA", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCPS", "DCTD", "DCTN1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DENR", "DERL1", "DFFA", "DHCR24", "DHDDS", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELOB", "ELP1", "ELP2", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERCC2", "ERCC6L", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FOXRED2", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLPH3", "GORASP2", "GOSR2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPI", "GPKOW", "GPRASP2", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH2", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFAP3", "KIFBP", "KIFC1", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L1RE1", "L2HGDH", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM7", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MAN2B1", "MANBA", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MED25", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL14", "METTL7B", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MIB1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL3", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL55", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NACC1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCK2", "NCKIPSD", "NCL", "NCOA5", "NDC80", "NDUFA10", "NDUFA9", "NDUFAF1", "NDUFAF3", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEK9", "NELFE", "NENF", "NF1", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F2", "NRBP1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXCT1", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIK3C2A", "PIK3C3", "PIK3R4", "PIP4K2C", "PIR", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA2", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PUM3", "PWP2", "PYCR1", "PYCR2", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEPK", "RABGAP1", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRM1", "RRM2", "RRP12", "RRP7A", "RRP8", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIN3B", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC15A4", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC37A4", "SLC3A2", "SLC4A1AP", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMU1", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPEN", "SPNS1", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX10", "STX12", "STX17", "STX3", "STX5", "STX6", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D10A", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TEX10", "TEX264", "TFAM", "TFCP2", "TFRC", "THOC1", "THOC3", "THOC6", "THOP1", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM13", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM14C", "TMLHE", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN6", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3C", "UBE4A", "UBE4B", "UBLCP1", "UBQLN2", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP53", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H13", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZCCHC3", "ZCRB1", "ZFR", "ZNF24", "ZNF281", "ZNF593", "ZNF622", "ZNF638", "ZPR1", "ZRANB2"], "leading_proteins": ["ABHD10", "ACOT7", "ACOT8", "ACOT9", "ACP6", "ANAPC7", "ANKLE2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "B4GALT1", "BCL2L13", "BSG", "CALM3", "CALU", "CASK", "CD47", "CDC23", "CETN2", "CLCN3", "CLUH", "CNP", "COA7", "COPE", "COX15", "CPE", "CPT2", "CPVL", "CRTAP", "CTSA", "CYB5B", "CYP20A1", "DAGLB", "DHCR24", "DNAJC3", "ECE1", "EFCAB14", "EIF2B3", "EIF3L", "EMC2", "EPHX1", "ERAP1", "ERLIN1", "ERLIN2", "ETFDH", "EXTL3", "FDPS", "FKBP14", "FKBP7", "FKBP9", "FOXRED1", "FUCA1", "FUCA2", "GAA", "GALNT1", "GALNT2", "GBA", "GGT7", "GLA", "GLB1", "GNAI1", "GNAI2", "GOSR2", "GPD2", "GSTO1", "GTF2F1", "GUSB", "GYG1", "HEXA", "HLA-A", "HLA-C", "HMOX1", "HSD17B4", "HSDL2", "ILVBL", "IMP3", "KDM1B", "KIAA0391", "L2HGDH", "LDAH", "LETM1", "LNPEP", "LPCAT1", "LTA4H", "MAVS", "MCAT", "MFSD10", "MFSD3", "MGST2", "MICU1", "MICU2", "MINDY3", "MIPEP", "MPP2", "MRC2", "MRPL14", "MTCH1", "MTCH2", "MTOR", "MTX1", "NAGLU", "NAP1L4", "NASP", "NIPSNAP1", "NNT", "NT5C3B", "NT5DC2", "NUB1", "NUCB1", "NUCB2", "OLA1", "P3H4", "P4HA1", "P4HA2", "PCYOX1", "PDCD6IP", "PDK1", "PDPR", "PDSS1", "PELO", "PEX5", "PFDN2", "PFDN6", "PGRMC2", "PHB2", "PIGG", "PITRM1", "PLA2G15", "PNPLA8", "POLR2B", "POR", "PPT1", "PPT2", "PREPL", "PSMB2", "PSMB4", "PSMD11", "PSME3", "RABGAP1", "RCN2", "RETSAT", "RMDN1", "RMDN3", "RPS9", "RUVBL2", "SCPEP1", "SDF4", "SEL1L", "SET", "SIRT2", "SLC25A10", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC29A1", "SLC30A7", "SLC33A1", "SQLE", "SRP9", "STARD3", "STAT1", "STOM", "STOML2", "STX17", "STX3", "STX5", "STX6", "STX7", "SV2A", "TARS2", "TBC1D10A", "TBC1D15", "TBC1D9B", "TEX264", "THOP1", "TIMM10", "TIMM50", "TIMM8B", "TMED2", "TMED7", "TMPO", "TMTC3", "TP53", "TRAPPC3", "TSN", "TSPAN6", "TTC19", "TTC38", "TUBB", "TUBB4A", "TUBB4B", "TUBB6", "UNC119B", "VBP1", "VDAC1", "VDAC2", "VPS37B", "VTI1B", "WFS1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAH", "YWHAQ", "YWHAZ"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0ae28dd681476805eab07c96f06e1f5d4bc0c1df --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:89aced87793f7662f0f038cf1a18d0dcf32b0d970a09fd5c4c1f5026807f6bfd +size 66960 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d52df6e997c35f7793876c41c4305cd00449755d --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.5 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9b1b95701697cba4af70332b283f0ba120e9eae2 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e985425731699435e58405c8b3dfcc361f51fce2 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.7288478249605723 1.9206876619717992 0.0547710959997362 0.2017333723379751 0.2190843839989451 6 P16615,Q9HD20,P98194,P05023 4 +EGF-type aspartate/asparagine hydroxylation site [IPR000152] 0.6445029624753141 0.5162199165978113 0.605700821436691 0.9758285062780564 0.605700821436691 2 O94813 1 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..475beff162458c5b1c54d908a6257d690c947c5b --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "EIF5A", "FASN", "NOTCH2", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP1A1", "ATP2A2", "ATP2C1", "SLIT2"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b03acd1e3c03e1517d4ea3475393649f47d8d9fb --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dd821d1cd6e7ccdfb0d35694ea80d53327e46241d316132851eedfdd34cef244 +size 186282 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1d7912e8e15d0f5dc2b422885c03e0f03612a957 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d5b3b8f2e0eb5f18f2b992740c97fac52e68a2fe886c32975df32167a626eeb9 +size 147557 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..db5e620f299633f16d79d453e4d447ed209466b3 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:91ee332d600c37a28e1f168ff0560ddfac21a2e4cd0180f694b8b75c26167bd6 +size 73261 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..767fc29485001951c2df591e43036c9a24adc6d7 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 12 20 3.470728348998588 0.0005190488078605 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 9.51244309544461e-08 0.0142466262053111 2.8899483668534896e-05 2.19272845709178e-07 1.2929972163241432e-08 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..39d0b9dafcda1f921d3ca117288b3bf1b87bde7a --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 72, + "title": "Average number of proteins per term", + "value": 5.486111111111111 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..daf65841b74570cb163262f834a59c086aae0462 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..69f340ed17968e5a3769964be7787d318d66b35e --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.7498883504613915 3.4707283489985876 0.0005190488078605 0.0366911637287493 0.0373715141659617 20 Q9BSK2,Q9HC21,P05141,Q9NZJ7,P12235,P12236,Q6NUK1,Q9Y619,Q9H2D1,Q9Y6C9,Q9UBX3,Q70HW3 12 +Sel1-like repeat [IPR006597] 0.8650427913100729 1.3996205069092431 0.1616269897357733 0.9999969275503042 0.3511805852805872 2 Q96BR5 1 +HEAT repeat [IPR000357] 0.4371474451997856 0.3876866519531056 0.6982479349297375 1.0 0.8667905399127775 5 Q8TEX9,O00410,P30154 3 +Hexapeptide repeat [IPR001451] 0.5582620144832144 0.2569250048975955 0.7972366672367193 1.0 0.941000656410554 2 Q9Y5P6 1 +Kinesin light chain repeat [IPR015792] 0.540157998683346 0.2140808298746996 0.8304840247957836 1.0 0.964433061053168 2 Q9H0B6 1 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c75a8efd35c4373b9d645a00541d8694744eede5 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kelch repeat type 2 [IPR011498]", "Kinesin light chain repeat [IPR015792]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "Paired amphipathic helix [IPR003822]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN4", "AGAP3", "ANAPC5", "ANAPC7", "ANKFY1", "ANKHD1", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC1", "ARMC6", "ARMCX3", "ARPC1A", "ARPC1B", "ASPH", "ATG16L1", "BIRC6", "BOP1", "BUB3", "CAST", "CDC23", "CDC27", "CDC40", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "CNOT10", "COA7", "COLEC12", "COPA", "COPB2", "CORO1B", "CORO1C", "CRNKL1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EED", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTB", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPB", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HTT", "HUWE1", "IFIT5", "IGF2R", "ILK", "IPO4", "IPO5", "JUP", "KAT7", "KDELC2", "KDM2A", "KIFAP3", "KLC1", "KLC2", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "LARP1", "LASP1", "LLGL1", "LRBA", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "MACF1", "MAP1B", "MAP4", "MED16", "MIB1", "MKI67", "MPHOSPH8", "MRPS27", "MTCH1", "MTCH2", "MTPN", "NAA15", "NASP", "NEK9", "NFKBIE", "NHLRC2", "NIPBL", "NLE1", "NOL10", "NOP2", "NOP9", "NOTCH2", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "P4HA2", "PAFAH1B1", "PAK1IP1", "PDCD11", "PEX5", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "POLR2A", "PPID", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRMT9", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP2", "RABEPK", "RABGGTB", "RACK1", "RAE1", "RAI14", "RANBP2", "RANGAP1", "RAP1GDS1", "RBBP5", "RCC1", "RCC2", "RNH1", "RPAP3", "RSU1", "SART3", "SCML2", "SCRIB", "SEC31A", "SEH1L", "SEL1L", "SGTA", "SHOC2", "SIN3A", "SIN3B", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL2", "TBL3", "TEX10", "TGFBRAP1", "THOC3", "THOC6", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS18", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WRAP53", "XAB2", "XPO1", "YTHDC2"], "leading_proteins": ["COA7", "GMPPB", "IPO4", "IPO5", "KLC2", "MTCH1", "MTCH2", "PPP2R1B", "SLC25A10", "SLC25A15", "SLC25A19", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6"]} \ No newline at end of file diff --git a/msigdb_gobp/advanced/idx2term.json b/msigdb_gobp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..7fa64f74aa901d8a5ad6403031879edcbe84cecd --- /dev/null +++ b/msigdb_gobp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial transport", "1": "Membrane lipid metabolic process", "2": "Anion transport", "3": "Nitrogen compound transport", "4": "Mitochondrial transmembrane transport", "5": "Mitochondrial respiratory chain complex assembly", "6": "Organic anion transport", "7": "Carbohydrate derivative transport", "8": "Sphingolipid metabolic process", "9": "Protein localization to mitochondrion"} \ No newline at end of file diff --git a/msigdb_gobp/advanced/plot_0.png b/msigdb_gobp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2bfa48fe2b821015deefe5f2a451630d16efb868 --- /dev/null +++ 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0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 1.8577044086968412e-08 0.0001599153115612 8.613529201399657e-07 3.056123406945332e-07 2.5192497572234827e-10 +Mitochondrial membrane organization 25 50 3.955709797202021 7.630774769529225e-05 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 2.4018729575750233e-09 0.0108990791164893 3.611186852814194e-06 6.778342498858873e-08 2.4692422526057762e-12 +Anion transmembrane transport 29 38 3.955232767832701 7.646017161611063e-05 18.02912621359223 42.29854368932039 1.9137296804814252 0.1915609440243116 8.771596162415214 5.032004157423188 1.8922368499585025 0.2935375719655638 8.037652816896147e-05 0.1008495778431075 0.0044166793623189 0.0003763683257436 2.6715701254780905e-05 +Cellular ion homeostasis 39 82 3.899535740179232 9.63773106252841e-05 24.48543689320388 87.34708737864078 0.921352068115914 0.4223079442129951 9.212290310790763 8.933596252465952 1.5207794649628892 0.4002972861975121 0.0077670858608514 0.1430583240174933 0.0475550848087982 0.0066354547880982 0.0036184134871659 +Establishment of protein localization to membrane 45 88 3.8838796045643935 0.0001028028268725 23.133495145631063 87.3616504854369 1.231448880072231 0.4195243824117992 8.397245527204214 9.510228790351464 1.3947369206386535 0.4065372973031916 7.472084204900986e-07 0.0163421355973242 0.0007546425024565 2.163056328212412e-06 1.7486441465496464e-07 +Protein targeting 56 107 3.7507382687309234 0.0001763146697215 30.48543689320388 111.54126213592232 1.595466660966077 0.3336055854889273 10.683999539888966 11.70327920021055 1.673091584234216 0.3988264387816677 2.97258662271458e-06 2.271471423927721e-05 2.7331631311118823e-05 2.862796607378169e-06 1.5456298087909778e-06 +Endoplasmic reticulum organization 25 45 3.73877866502438 0.0001849164411671 14.91747572815534 43.67718446601942 1.1418424810127707 0.3725584991544436 6.208589840117394 4.768440325801463 1.6823827875834556 0.3705219831566139 1.2342237313308365e-07 0.0514861271532366 0.0365585180593606 1.3599520011241973e-05 9.660090844099769e-08 +Nucleotide transport 12 14 3.6504982628667983 0.0002617320796669 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 9.208341590817223e-10 0.0068317681715133 0.0019068669696529 2.914413274201657e-05 4.257020115260835e-11 +Protein targeting to mitochondrion 27 46 3.637270987970055 0.0002755419948587 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 4.912341455062464e-06 6.039351288585226e-05 2.053210813748613e-05 4.9861626098174725e-05 1.7391498666161893e-07 +Organophosphate ester transport 18 28 3.6237088769263313 0.000290408469435 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 2.1115111793726198e-07 0.0551599902794207 0.0069551143734033 0.0001165831500094 4.681173696329203e-09 +Metal ion homeostasis 36 74 3.5696129401421297 0.0003575090630738 22.37864077669903 79.5 0.7762327689006491 0.4501210966631583 8.485414676383348 8.298876985671072 1.3957415688189287 0.3857448193070677 0.011091620508909 0.1320457949075564 0.0408976472683376 0.0116878222785546 0.0022286511437342 +Inner mitochondrial membrane organization 16 24 3.533736070500465 0.0004097300046206 9.985436893203884 20.800970873786408 1.138268089020681 0.2873707765098114 4.6289277788641146 2.4012939531921327 1.609232985153232 0.3229583948801056 6.993845449875131e-08 0.1635258499471353 0.0004155585626268 2.4880325513906888e-05 3.871321030693187e-12 +Transmembrane transport 106 202 3.4868938526892324 0.0004886652671014 67.45631067961165 211.1359223300971 1.8122664376950308 0.3598356673827246 27.267027885156203 22.354947126810902 2.251277763144546 0.4188333713481413 1.6725670868282176e-10 0.0001955030142979 6.304885449921873e-09 3.312394699038313e-09 1.220826327818679e-10 +Ion transmembrane transport 67 147 3.404963934914252 0.0006617279242462 47.09466019417476 154.11893203883494 1.555073205784263 0.3634279635891347 19.61122797656 15.97124025754773 1.9676287128633565 0.411597796705808 5.748284322349421e-07 0.0058298565574542 2.831994307632962e-07 5.921452100752553e-07 1.2712339399075553e-07 +Cytochrome complex assembly 9 14 3.3957303597833017 0.0006844575096716 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 2.9979119853227453e-05 0.0115082778780227 0.0041517217414646 0.000144725329193 3.0899315726376227e-06 +Protein insertion into membrane 14 29 3.392336336416013 0.0006929931795829 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 3.046268053955238e-07 0.0248381956323572 0.0014189260290535 3.108801921887044e-06 1.0327694231659982e-08 +Glycoprotein biosynthetic process 25 53 3.3869691193138407 0.0007066934182409 16.72087378640777 51.87378640776699 1.042113998842759 0.381483262234126 6.756316800759528 8.908847583990125 1.5232206853916193 0.3819786061588057 0.0056809019794517 0.603038217660401 0.1101988716805679 0.0415784925143275 0.0022497685932203 +Ion homeostasis 43 97 3.385919720984996 0.0007094013319275 28.021844660194176 105.69174757281552 0.8349951537384392 0.4299135801564597 10.40966729997928 11.411952082971936 1.4722934854811005 0.3963893325418664 0.0076602957173345 0.0745157705462292 0.0144227917277509 0.0029403615639838 0.0031752105289278 +Protein transmembrane transport 19 25 3.363899632693984 0.0007684948537427 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 0.0036196916365728 0.0020640692536444 0.0001474440444245 0.0016834035897202 0.0009271037060534 +Establishment of protein localization to mitochondrial membrane 11 19 3.34169132591725 0.0008326960605575 5.572815533980583 16.524271844660195 1.1986544459127668 0.291784793504827 2.8501471321161915 2.5441524813639957 1.2232399066733852 0.3232066755573589 2.552755667758062e-08 0.0073558029266518 5.053603155069604e-06 1.5789403182994546e-07 1.372436955725948e-09 +Membrane lipid biosynthetic process 15 24 3.332950506457572 0.000859302271821 8.866504854368932 23.050970873786408 1.3229385051208649 0.2431293012321725 4.229937732502716 3.4850337476777224 1.635527795490498 0.2996124846932806 0.0121657674851947 1.0 0.5484830827387088 0.0036501932708164 0.0019737688005078 +Inorganic ion transmembrane transport 53 106 3.2991661895239464 0.0009697248321911 32.300970873786405 111.99514563106796 0.9881513097876132 0.4268253140664947 13.185263141323642 11.586314982845243 1.7161030277526947 0.4113555760685328 0.0005582573719658 0.0811245339020894 0.0001014908476459 0.0002402854264167 0.0001279342236155 +Endoplasmic reticulum to golgi vesicle mediated transport 29 70 3.286748476412095 0.0010135131515924 17.32766990291262 65.39077669902913 0.808881464821498 0.4942452999677598 7.539018980743236 6.620812461410292 1.284359804176963 0.3933269611423161 2.706157919257709e-05 0.0176779282664691 0.0246695053344801 0.0018745467202956 3.788616181424059e-05 +Lytic vacuole organization 10 21 3.2489880583544486 0.0011581634007906 8.677184466019417 23.79368932038835 1.067589638534915 0.1668002350701783 2.8744208086829883 3.077266940940983 2.0111064761459874 0.2496786569477077 0.000388344925329 0.2516504230112798 0.1132051672598368 0.0148252690690975 0.0001266725713312 +Glycoprotein metabolic process 28 62 3.246937171791453 0.0011665413838028 18.59223300970874 59.577669902912625 0.8707431654759812 0.409720724299967 7.543964208858723 9.989377193127202 1.488085349392555 0.3835029669336279 0.024814346380707 0.6674460421157596 0.1725838712124082 0.0985392647013521 0.0070276924613435 +Cation transmembrane transport 49 112 3.23592500756585 0.001212492342296 33.43446601941748 118.4004854368932 1.1701058025505957 0.4085228823574113 14.425169362008605 12.553856783980793 1.6663185381795875 0.4066910074955585 0.0004410210657731 0.104162521549783 5.619832515892605e-05 0.0002924230666717 0.0003156403882925 +Divalent inorganic cation homeostasis 24 49 3.229674762456852 0.0012393111237367 15.361650485436892 54.019417475728154 0.5485088157809707 0.5170537035394376 6.04857242197355 6.215359275440269 1.1779017300469032 0.3778837346959196 0.0096648472252076 0.5891657340012217 0.2574752425413383 0.0339633893520725 0.0078250151240571 +Organic acid transmembrane transport 20 28 3.2273520887404405 0.0012494161763851 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 0.0821087972914418 0.3208381238265493 0.0415809882988902 0.0444212272681039 0.193206221510934 +Purine nucleotide transport 9 11 3.209637385656824 0.0013290251707789 4.970873786407767 10.817961165048544 0.961055494000064 0.2880106547862709 2.8308505383502496 1.988649275322177 1.3314072021441097 0.3042395363852717 3.315699882295524e-07 1.0 0.1758008751515455 0.0011993766429203 8.073414733415837e-09 +Ceramide metabolic process 12 19 3.198882368861841 0.0013796144779918 8.191747572815533 19.060679611650485 1.0632949889077032 0.1865092544415649 3.2982239784478966 2.5917545738626013 1.8901201919357584 0.2494992632187684 0.0012759235178136 1.0 0.4242240140575919 0.000423196822916 1.4660781943737655e-05 +Liposaccharide metabolic process 12 17 3.192392800417306 0.0014109930844665 7.393203883495145 16.839805825242717 0.7162233803449398 0.1804705798886219 2.8837934205508033 2.921890590438037 1.8930166841377585 0.2403675114219934 0.0060097949977065 1.0 1.0 0.0129296559640097 0.0066608970268297 +Golgi organization 26 60 3.174666441036281 0.0015000883200566 16.643203883495147 56.43689320388349 0.631232933893225 0.5683910993217528 6.594450257690171 8.413373430660274 1.0599635722797485 0.3790700076783576 0.019103201960697 0.119407916442016 0.006774840164175 0.0309649911309741 0.0071973864359223 +Glycosylation 20 45 3.165186115480062 0.0015498378076186 13.33495145631068 45.42718446601942 0.831363055351092 0.4028474919440285 5.5712021107485015 7.578523489860055 1.3433056638769032 0.3649215649501745 0.003341631367421 0.5446368300228982 0.4634232241325184 0.0169952178401221 0.0054702332042432 +Carboxylic acid transport 20 31 3.1391247834681963 0.0016945327221196 12.351941747572816 33.69417475728155 1.517249458545343 0.2522623764771551 6.23371050940395 4.11174791553619 1.419876490432768 0.3135855212793009 0.0063296620160599 0.3985608327989486 0.0801526286479979 0.0420396019683425 0.031406882696227 +Membrane lipid catabolic process 10 12 3.061180541288435 0.0022046611404793 5.854368932038835 11.361650485436892 0.500872843713425 0.1363587272813367 1.9603237645724247 0.9867004907377388 2.113024793917032 0.2289617793743788 3.315699882295524e-07 0.0919337377678228 0.0155240337321844 2.663955417651745e-07 2.2237850571674797e-06 +Sphingolipid biosynthetic process 10 16 3.031530332567517 0.0024331747220485 6.543689320388349 16.33252427184466 1.3108583596388097 0.2293036031089034 3.2058099533310203 2.4273143169149307 1.5209865792019848 0.2861850290041513 0.0066029696808292 1.0 0.4353012614103685 0.0029289523616429 0.0004954067345962 +Ion transport 87 197 3.000985364028129 0.0026910749931599 59.95631067961165 203.33495145631068 1.28794420214731 0.4483240343684334 22.7179419701651 20.293344878478432 1.852388371824549 0.4292871393353351 3.1096443815262794e-08 0.0304426514069823 7.495308044196196e-06 4.69452385779399e-07 5.220367996347568e-09 +Mitochondrion organization 85 188 2.9955340643971136 0.0027396469918707 56.45873786407767 188.26941747572815 1.5905300936136977 0.4100157441778524 20.15716756472138 18.40319032732565 2.034523716094369 0.4327537677377048 4.4015868773208966e-12 0.0001934883081307 2.4266310584962333e-08 7.414058143150954e-11 6.76408845623614e-16 +Lipoprotein metabolic process 10 22 2.9650021155146216 0.0030268084811782 5.504854368932039 19.114077669902912 1.0723975558987071 0.2794846862458811 2.648039342123219 3.7213756556771336 1.2556798055308762 0.2951644225033464 0.0417308550900142 0.0627750690965546 0.0483217377147592 0.0169357854376417 0.1191020144375228 +Intracellular protein transmembrane transport 15 21 2.9401621883438103 0.0032804048673795 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 0.0267348588950776 0.0196403757049561 0.0091243340822671 0.0230341265569123 0.0209086601360684 +Nadh dehydrogenase complex assembly 10 26 2.9385103103719787 0.0032979368853398 9.266990291262136 26.96359223300971 1.1245271541492263 0.3013677937017552 4.122702675359976 4.029157649894909 1.4460543016521823 0.3224564676521605 0.0002612010376317 1.0 0.0173242512102645 0.0024554723849656 7.783061920382117e-05 +Oxidative phosphorylation 14 60 2.929023725676604 0.0034002846688614 18.140776699029125 60.61893203883495 0.8137621380364766 0.3661293054253088 7.750013302753429 5.582386553809936 1.7413544544034578 0.3762713520958283 4.071475780236153e-05 2.0675682037151048e-05 1.7822031869587478e-05 0.0001417519274813 5.912529240148753e-05 +Cellular monovalent inorganic cation homeostasis 13 24 2.889796776665526 0.0038549094477708 8.191747572815533 25.12378640776699 1.1978511848260835 0.2636491484517694 3.558748260132903 2.9783551257949803 1.4212259473978417 0.3021468238591936 0.027277006892699 0.2552681350600493 0.0207328276809773 0.0034676048515423 0.0750518175373725 +Endoplasmic reticulum tubular network organization 6 12 2.885161707719634 0.0039121265807713 4.150485436893204 10.555825242718448 0.8961707031484618 0.3171343629503343 2.1669796342432037 1.8339543060404635 1.2935176897309475 0.3199619326088047 1.4781136073551245e-06 0.0786913117950012 0.0113213926532688 3.906142953800441e-05 7.850220860580527e-06 +Aminoglycan metabolic process 11 17 2.875659344071102 0.0040318458468331 6.650485436893204 15.218446601941748 0.5538240398360251 0.1973407167351751 2.4739761552565955 2.4752855115427597 1.8355272359461776 0.2521795038965069 0.0022155464387141 1.0 0.1194965359594502 0.0629955787418294 0.0001720503108284 +Nucleotide transmembrane transport 7 9 2.846325653783061 0.0044226940151306 4.029126213592233 9.24271844660194 1.3657020532080593 0.1972377481261837 2.230443861436908 1.484326001257553 1.1744026177454787 0.2553979780962895 1.6423347005604462e-05 0.0026008925831016 0.0100519320580488 0.0004862334359502 2.701670996055716e-07 +Ph reduction 4 12 2.830647609838979 0.0046453870458629 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 0.0036252861513815 0.1263420182810564 0.0293903981750984 0.0004989114687539 0.0103633783340074 +Organic acid transport 28 44 2.797775165385204 0.0051455917068707 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.0756428431991632 0.4854356723902606 0.1449031461986719 0.1154859850799389 0.0700430668652725 +Sterol metabolic process 15 39 2.7921542594079285 0.0052358388443238 11.932038834951456 38.44660194174757 1.1656335789111734 0.2523239777622673 4.346099994655023 4.0619669904912925 1.6676089351046874 0.3062687621764124 1.6649426361863718e-05 0.0627750690965546 0.1967082241040804 5.918077284044873e-06 5.37153859631512e-07 +Regulated exocytosis 14 33 2.7893503013338243 0.005281390593391 9.385922330097088 34.342233009708735 0.5889869251407832 0.528096964379338 3.868480531815476 4.573760415025692 0.9122431884356956 0.3457208176316948 0.0417412279249663 0.4463627535095094 0.1126980972536071 0.3425620879071548 0.0154834756587895 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 15 26 2.774529494105064 0.0055281621148619 7.771844660194175 26.825242718446603 1.1714448828781496 0.3436005361805324 3.811248488859092 3.450558374586287 1.1733172803389544 0.345676809182098 0.0003375664037662 0.0014578554854327 0.0102837000876808 0.0008884443610078 0.0017420499960669 +Ceramide catabolic process 5 7 2.7501090975303035 0.0059575425973057 3.8592233009708736 6.531553398058253 0.1286784152295923 0.1423502941444668 1.429436503356119 0.7012295128365029 2.0219843992394857 0.2259194528389771 2.156641983966758e-06 1.0 0.1094892401774078 5.522373670119844e-06 9.246798264487089e-06 +Regulation of cellular ph 5 20 2.741487423810184 0.0061161702055765 6.885922330097087 20.844660194174757 1.215766922704761 0.2375185297794358 2.9319293283093293 2.765976649626597 1.4143296516981956 0.2875299337708636 0.0100052333540776 0.2107016729382093 0.0115248505447769 0.0011113418092766 0.0305407497227627 +Regulation of ph 5 20 2.741487423810184 0.0061161702055765 6.890776699029126 20.859223300970875 1.2151699598837196 0.2373503364294603 2.930458126920059 2.7746402510870145 1.4154672965603718 0.2873526492076106 0.0132544128541003 0.2220822570468345 0.0135419734012732 0.0015231541907095 0.039409055534926 +Phospholipid metabolic process 34 79 2.7292209203950555 0.0063484158421298 18.805825242718445 74.80339805825243 -0.0109191555178773 0.4658808189502442 8.677118948764809 11.032066592781655 1.2956045948013235 0.3559409313369701 0.1022146361816489 0.7103531543783221 0.7057774177200682 0.0208004730726723 0.0062083021076098 +Vitamin transmembrane transport 4 6 2.7283272718657945 0.006365641799263 2.9344660194174756 6.094660194174757 1.6910321805591797 0.1136175735100163 1.344920850275403 0.8913122381585616 1.0580472895861666 0.1862049292817703 0.0001661698784952 0.0697581245313758 0.1349531130589082 0.000371706641515 0.0005338561483377 +Vacuolar acidification 4 9 2.7185845762490684 0.006556189213603 3.4757281553398056 8.922330097087379 1.27407749822917 0.1611429668415415 1.4148632661931722 1.303016071016461 1.4195929612668792 0.2212670077717619 0.0004315578367149 0.083126337411673 0.0126574737404708 5.302129833761715e-05 0.0013491401517078 +Intracellular transport 170 537 2.710807676723447 0.0067119544826115 120.90291262135922 544.3956310679612 0.5500812282996078 0.6924011803517542 31.43517433849213 53.582766758854405 1.193070641867047 0.396756529943003 1.6933443891626288e-07 0.0001617730155477 3.529148016820546e-05 3.2853488190859216e-06 2.2273495369268459e-10 +Protein transmembrane import into intracellular organelle 11 14 2.706932558128794 0.0067908051283478 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.0254551432022514 0.0090330503435184 0.0028960612595367 0.0352396407582777 0.0138780941766985 +Proton transmembrane transport 20 44 2.702768515484236 0.0068764617616443 14.28640776699029 43.01699029126213 0.7821394801431882 0.3918912894345224 6.076814900000799 3.1076483585332 1.5710697941383835 0.3739424994204808 0.0008147110823925 0.0102936075696032 0.0020689855180955 0.0019595403906339 0.0019322197171993 +Vitamin transport 4 7 2.676004834488852 0.0074505570394989 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 0.0017752561093411 0.1093006244161378 0.2070995190727305 0.0024379570615939 0.0052582215982291 +Protein localization to endoplasmic reticulum 17 36 2.66492145554823 0.0077006306202573 9.50242718446602 34.50485436893204 0.9935384348474128 0.428255638055916 4.399083524593319 2.6617527855555916 1.1934894982037212 0.3717243536861919 0.0002612010376317 0.2406936845278361 0.0173242512102645 0.0024554723849656 0.001584251501391 +Inorganic anion transport 15 23 2.662621187071985 0.0077534644811023 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 0.0043572934514569 0.0432831882721129 0.0005115527825537 0.0013505003452077 0.0017361489715071 +Purine containing compound transmembrane transport 6 8 2.648180542634452 0.0080926293700782 3.6432038834951457 8.228155339805825 0.8480777288434221 0.3004167480224937 2.0847056152178514 1.431742605530374 1.2278207398320582 0.2967021731271802 0.0001143137751925 1.0 1.0 0.0439142352380576 1.5745699404944486e-06 +Cation transport 56 144 2.644562290245101 0.00817966499425 40.9247572815534 152.4733009708738 1.0106305648473772 0.4693050539746304 15.98502541638414 15.374508146736815 1.5607432077940149 0.4143686874753333 0.0011645298551121 0.2152607060183915 0.0002671554170624 0.0009747253272736 0.0006036485947358 +Steroid metabolic process 29 65 2.638108061697375 0.0083370010576553 17.82766990291262 66.9247572815534 0.9974586731388552 0.3270410156332073 6.090491666967852 5.93996409793671 1.7133199907504504 0.3720334828404655 2.400318088130685e-05 0.1723298875515411 0.1893952239009581 5.454908265891026e-06 6.19717500459631e-06 +Glycerolipid biosynthetic process 27 49 2.6330694924917166 0.0084617032295362 13.466019417475728 44.71844660194175 0.9430872689732808 0.3767257192898063 6.88753698417372 8.249645447783736 1.3199493331746477 0.3584243730449019 0.2476219675817929 1.0 0.8286090733920952 0.1502057024283079 0.0579961117020803 +Negative regulation of calcium ion transmembrane transport 3 7 2.6287065401034657 0.008571028954361 2.1067961165048543 7.601941747572815 0.9433101814663925 0.3101119054926485 1.594362771690279 1.170758660555987 1.028728108691548 0.2750664841729511 0.0049881070407295 1.0 0.014058804472369 0.0009779431698101 0.0119688845689888 +Secondary alcohol metabolic process 15 43 2.626628806913937 0.0086235347614098 12.097087378640778 42.24514563106796 1.5200936296432006 0.2566232504859334 4.463475425703621 3.883072640851752 1.3223501002339118 0.3210874999447533 2.1531580979321056e-05 0.0653891722063119 0.2037147080402499 7.443708891646707e-06 7.601481383823173e-07 +Establishment of protein localization 160 505 2.621532660388522 0.0087535374482108 118.26941747572816 516.7257281553398 0.6520395559374618 0.679532677582667 31.472560658738065 53.21298128179791 1.2523101724416292 0.4083128036600569 2.539701805686817e-07 0.0016791240650154 8.679429431334448e-05 2.5444798395795388e-05 1.2086154070758008e-08 +Vacuole organization 21 55 2.6160001672590045 0.0088966514006698 14.220873786407768 51.74514563106796 0.8524122478550634 0.3147425083910056 5.370022076358251 7.439112114793103 1.7567175511320523 0.3563110134355993 0.0059247754248939 0.5287686777468734 0.0620226994518361 0.0347525410648739 0.0035526402796452 +Regulation of oxidoreductase activity 6 15 2.608463600501946 0.0090949683971084 4.745145631067961 16.524271844660195 0.8435277245089666 0.3527293456818395 2.542951562396442 1.641953963820047 1.0033906386071183 0.2899852749738094 0.0040267290554102 1.0 0.0949012099695084 0.0018561414510811 0.0150905845261323 +Regulation of lysosomal lumen ph 3 6 2.608386314704928 0.0090970223752495 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 0.0019802696370409 0.0697581245313758 0.0088504827764808 0.000371706641515 0.0049176108076387 +Oligosaccharide lipid intermediate biosynthetic process 3 6 2.602890656201211 0.0092441431241847 2.2742718446601944 5.390776699029126 0.4920123476052065 0.3335995467983793 1.5024311055989734 1.8021595402153228 1.3008390374829126 0.2934249582958821 0.0040574836292075 0.083126337411673 0.1596960736798767 0.0007869115437374 0.0098193480789534 +Monovalent inorganic cation homeostasis 13 26 2.594908318834731 0.0094616153623645 9.014563106796116 27.87378640776699 1.1567920478867002 0.2845186374336156 4.051822262152646 3.607380814764068 1.4117439861533438 0.3149022278800241 0.0576595663430084 0.297366720714231 0.033011066423499 0.0083652800039346 0.143549387276975 +Glycosphingolipid metabolic process 6 8 2.592205166136297 0.0095362881800489 4.764563106796117 9.184466019417476 0.4485135251287195 0.1553285492394019 1.7516723087054535 1.7320372023153958 1.93068386398988 0.2217231968869004 0.0013161135129504 1.0 1.0 0.007920049564759 0.0008750939624126 +Peptide catabolic process 6 10 2.576623502413297 0.0099770556562917 3.871359223300971 10.351941747572816 1.5413280472635258 0.1625248535751528 1.454973091229298 0.9501768442987896 1.1353491763523988 0.2229381591694359 3.585597436456029e-06 1.0 0.1677870330809631 0.0102137155300364 1.8677763344678236e-05 +Atp transport 5 6 2.546247064015347 0.010888809101609 3.4805825242718447 6.233009708737864 0.5838786306840471 0.3211615036091749 1.83337760624298 0.8807971179633459 1.3636108978108328 0.3170401972517012 0.0002190493099042 1.0 1.0 0.0010588751859522 9.533521740063692e-07 +Glycerolipid metabolic process 36 67 2.540437365038076 0.011071392229643 16.934466019417474 64.79854368932038 -0.000323163470851 0.4552448147740581 9.046432352430308 10.372466251166422 1.3758971299503038 0.353332456533291 0.3289519896699771 1.0 0.9097388217924408 0.1434581333664698 0.0547783034551529 +Respiratory chain complex iv assembly 5 9 2.534154321463812 0.0112719078762031 2.7475728155339807 6.451456310679611 1.036831430168084 0.2562354664331627 1.605321530277248 1.669274831081891 1.262804896468415 0.2848709091577191 0.0021511085021245 0.1135912525516411 0.0237627189197599 0.0028478177309091 0.0010313331646429 +Organelle fusion 21 46 2.528019436003142 0.0114708001656143 14.74514563106796 45.383495145631066 0.6448767361523368 0.5292766623385164 6.293825046556003 6.576179389035289 1.1045479661060835 0.3741954647136961 0.0316896562650978 1.0 1.0 0.5364007352225043 0.0001480238274956 +Sulfur compound transport 5 8 2.518038872716992 0.011801029600341 3.504854368932039 9.429611650485436 1.339223354728307 0.2167503093092372 2.046184165461596 2.1092484385198076 1.0728301411615704 0.2604171804663498 0.0013161135129504 1.0 0.0038117145357013 0.0449350347407693 0.0046379242911556 +Lipid localization 30 73 2.5097135034417835 0.012082914811905 20.1504854368932 74.27912621359224 1.3966421040883936 0.3001252105784707 7.306180038477171 9.39465098860316 1.572418240819249 0.3627304234720817 0.0007209209076885 0.0895964033786971 0.0615495803785245 0.0003082164034328 0.0004649226172579 +Metal ion transport 24 91 2.509259167907645 0.0120984682831593 24.868932038834952 99.21116504854368 0.6600358663497399 0.5322554902435589 9.162889792248723 11.473971032908404 1.1670714049066973 0.3920241658733104 0.169454010753478 0.8183578517998993 0.0499768395118841 0.080590415234033 0.0832233948088459 +Dicarboxylic acid transport 10 16 2.501958010284152 0.0123508572363875 5.718446601941747 16.097087378640776 1.1205667041867788 0.2998586575349944 3.584398436287638 2.226340822602054 1.0973546365412417 0.2986830136605488 0.0732969355710917 0.1835089509173778 0.0614247268920475 0.0808776862517318 0.1458719137718038 +Amino acid transport 13 18 2.486443048114914 0.0129027219931709 7.771844660194175 19.75 0.8410032854505353 0.3449280742441291 4.117377746800764 3.003739578643708 1.287399790463736 0.3206698223659758 0.264656144827126 1.0 0.4876012483283494 0.5011508815608771 0.2443072639610269 +Negative regulation of calcium ion transport 3 8 2.4760972324722115 0.0132827398798365 2.378640776699029 8.815533980582524 0.865801675063994 0.3348216966365627 1.767376998119782 1.5264501163101216 0.996781239251156 0.2731835761958332 0.0254551432022514 1.0 0.0334071197556988 0.0056128198685199 0.0557230881301947 +Transition metal ion transport 6 16 2.461523909219764 0.0138348176244507 4.70873786407767 14.08980582524272 0.8861898222657586 0.2678437025860737 2.4756329698054333 2.718007722894407 1.3738160036140448 0.271065502827487 0.0718080677393813 1.0 0.4353012614103685 0.0543044475705096 0.0659378334998033 +Amino acid transmembrane transport 9 13 2.456923218120916 0.0140132633758252 6.213592233009709 14.228155339805824 0.7890307267204019 0.3318923540291705 3.493823914060917 1.9561661273054285 1.3497309258640615 0.3227865040448734 0.2625002132306564 1.0 0.3655284832956332 0.3157753203157507 0.4023686447738411 +Vesicle docking 9 18 2.4520098768741985 0.0142060762534348 5.046116504854369 16.300970873786408 0.2955335573812314 0.5566344803804099 2.726231700974349 2.3037957343391864 0.8857805503827542 0.3078464388536641 0.0894994943186356 1.0 1.0 0.6691111110298131 0.0013003096338674 +Positive regulation of peptidase activity 16 36 2.451115411026653 0.0142414282841791 10.402912621359222 41.05582524271845 0.5528457293594794 0.5353148532065843 3.6877903061155113 4.060739093918417 0.9383664509883394 0.3555881721715914 0.0399332747199633 1.0 0.6913649792128338 0.3370386727072499 0.0700988077400227 +Glycerophospholipid biosynthetic process 29 45 2.444966191366489 0.0144865721142724 12.407766990291265 39.55339805825243 0.6228968293784067 0.4586227574071144 6.110530292090928 7.803693618041913 1.233194093755117 0.3515784330467275 0.2602741282901563 1.0 0.7893446820396504 0.1923169229713429 0.0899301375969372 +Cristae formation 6 10 2.4430835499695336 0.0145623655482345 4.740291262135922 8.861650485436893 0.8982766043222677 0.3392698633906088 2.216011442046921 0.6593503673812457 1.2485531022675598 0.3418736408093433 0.0014965097014554 1.0 0.1265462710440741 0.0439142352380576 2.763867591720716e-05 +Protein targeting to membrane 17 33 2.4179564386621077 0.0156079451908719 9.03640776699029 34.86407766990291 0.8678999397376299 0.4369909067843477 3.776027437978551 4.807050937156168 0.9685770296783628 0.3476738150633759 0.0566604597178804 0.0707254675278004 0.0570724957906687 0.0064725887331866 0.0747071460891875 +Membrane organization 76 223 2.4099091396666994 0.015956493800328 62.02427184466019 223.60922330097088 0.9560408776070136 0.5603311757674675 21.467957454898308 21.375973545731355 1.611091026762519 0.4273954777865132 4.913528354212468e-10 0.0399875865627003 0.0001468472635592 4.20511674884996e-06 7.547735171968882e-14 +Calcium ion transmembrane transport 16 36 2.405809277861255 0.0161366866328207 10.5 40.51456310679612 0.3400819096715784 0.5565528717247777 4.784430655681941 4.7513188310580725 0.9547513033794968 0.3464854172738558 0.0628954912805248 0.4727213828993198 0.0087667818001301 0.0413241482542941 0.0270139497455811 +Steroid biosynthetic process 18 42 2.4035370620969307 0.0162373210070043 11.728155339805824 44.80825242718446 0.9874364787035632 0.3935759881445143 5.016369659264937 4.35272817633461 1.2862817592315925 0.3680333006848349 0.0010608580615418 0.3746890061856052 0.2391023108138102 0.0005549428323582 0.0002345207007022 +Phospholipid biosynthetic process 30 60 2.390703505716348 0.0168161267989839 15.191747572815531 54.88834951456311 0.3601791313916425 0.5325104042072244 6.85810624136386 9.315774292776531 1.1122724170508866 0.3517335331311575 0.2006746561919681 0.6107582205032194 0.5597140736485569 0.0993259474695593 0.0271178347995757 +Lipoprotein biosynthetic process 7 17 2.386016273789324 0.0170319973553549 3.837378640776699 12.817961165048544 0.5159177916871569 0.4870101230655305 2.4216380804227313 3.0215034704254133 0.9442820469649724 0.3192432047465013 0.239630929796809 1.0 0.4724360815693985 0.0756483536674149 0.4011143926978829 +Reactive nitrogen species metabolic process 4 13 2.378097775788269 0.0174022108474685 3.9805825242718447 16.550970873786408 0.5187061899010498 0.4616229774504417 2.0608725766457097 1.6501909360329357 0.9419567550357958 0.306935586730602 0.0244989445999675 0.1913705796369965 0.3467918934582977 0.0213813720021448 0.0610180463767549 +Protein import into mitochondrial matrix 7 9 2.3658270659525966 0.0179898453703961 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0174514302411212 0.0022827689145391 0.0003602808960722 0.0051503840765812 0.0049176108076387 +Respiratory chain complex iii assembly 2 5 2.365769524185282 0.017992641451787 1.8470873786407769 5.160194174757281 1.360931378136811 0.1995688008303064 1.0650749835200868 1.2360161344522411 1.0120439004969468 0.2366879233397748 0.0026155774748029 0.0378187125466048 0.0743799864466655 0.0148625463558957 0.0053334351931861 +Hormone metabolic process 14 29 2.365620256534789 0.0179998964707566 8.95631067961165 28.65776699029126 1.130508313948193 0.2963365150575847 3.9674689274001818 2.5345884681715156 1.346801337886388 0.3240077568826507 0.0110426597948338 0.3746890061856052 0.0665208936004256 0.0090970875375293 0.0025288077053784 +Glycolipid catabolic process 4 7 2.3608008034913923 0.0182355227068047 3.6310679611650487 6.451456310679611 0.1059933679561382 0.1697430158083476 1.434595381284437 0.7664524352299261 1.9023109688101565 0.2365791262889882 4.815836726362641e-05 1.0 1.0 0.000142755965642 0.0001590313802548 +Endomembrane system organization 66 173 2.3606006795400183 0.0182453650281364 47.08980582524272 169.73058252427185 0.8987911429216844 0.5600148744834964 15.914797198368843 20.49740065572335 1.4161383035869868 0.4170367608227654 2.60284160555448e-05 0.2845607441622844 0.0119532953426225 0.0027262027870232 7.673506029124629e-07 +Protein n linked glycosylation 7 20 2.3586914365977827 0.0183394978382465 6.177184466019417 18.78640776699029 0.2004880128160887 0.4683260162783809 3.1676710128395498 3.0254598797887766 1.208633498192774 0.333447209788965 0.0054573297990931 0.2406936845278361 0.1039407380726692 0.0024554723849656 0.0059899182032361 +Membrane docking 13 32 2.340083572806292 0.0192794251853061 7.973300970873787 28.83252427184466 0.3013065671948621 0.638505559524285 3.967313754164099 3.197937811998676 0.8147042438070861 0.3288047187933706 0.0432624889010775 1.0 0.4825947600252522 0.4934040207883591 0.0015503267588381 +Negative regulation of cation channel activity 2 5 2.3373283636664035 0.0194221168183659 2.133495145631068 6.012135922330097 0.3843341472061108 0.4773896383730598 1.4478455428656238 1.1179681209181225 0.991066221927023 0.3079680390661607 0.0287882540820239 1.0 0.1596960736798767 0.0087554356838108 0.0541965943180989 +Ceramide biosynthetic process 6 10 2.329411589017956 0.0198372717133559 4.033980582524272 10.24757281553398 1.048715387316577 0.2344614502118888 2.237979905601341 2.0281678881596505 1.4071730245015133 0.2685344998940062 0.0420089305779128 1.0 0.2872333566147377 0.0097601039903573 0.0062617463102783 +Endoplasmic reticulum membrane organization 6 9 2.3271370091733816 0.0199579743080684 3.5679611650485437 8.12621359223301 0.656874598832497 0.271683145803182 1.813579499342004 1.2879547393790816 1.532817064292788 0.2945772195616556 7.583382097353882e-05 0.0607401038440192 0.0066572828402184 0.0002022933287296 0.0002481332774246 +Amyloid fibril formation 1 7 2.325910226521521 0.0200233403667302 2.7233009708737863 8.089805825242719 0.5011823985301114 0.4066260207600095 1.722535041056919 1.3984016400026793 1.0784339491013113 0.3045914344390437 0.1878361950417842 1.0 1.0 0.090818300458346 0.2722934148112151 +Calcium ion import 4 12 2.324545734944495 0.0200962633291945 4.516990291262136 12.686893203883496 1.0417029373125424 0.2391249176108038 2.3196506830054986 1.9148178088324157 1.3383409214307818 0.27915846054651 0.0121807700050573 0.1635258499471353 0.0052800410185589 0.0596874537258691 0.0321953433845534 +Mitochondrial cytochrome c oxidase assembly 4 8 2.3167852581381507 0.020515432477675 2.344660194174758 5.764563106796117 0.9954600272926416 0.2681565835601643 1.449018962088891 1.4364892997002987 1.2150903662861117 0.2820677765861404 0.0086084367183884 0.1006582454154426 0.018640880521655 0.0017432511761074 0.0035298468720628 +Alcohol metabolic process 27 83 2.308479432713334 0.0209724854830166 19.300970873786408 81.99029126213593 1.0392616248309592 0.3936245775900834 6.9548962308345 7.403089286448431 1.208378917036781 0.3759976884392474 0.0001270667460862 0.2658534516448619 0.1417075877652198 4.7186904172996896e-05 9.814753258299877e-07 +Calcium ion transport 15 51 2.2953963370663835 0.0217104210852661 14.359223300970871 56.12135922330097 0.5117941214501432 0.5203785154770082 6.100858397237751 6.232924643281249 1.067298802513521 0.3756526252141436 0.0706924024755187 0.5748186848116099 0.0069028868703925 0.064317373781281 0.024553037478424 +Glycerophospholipid metabolic process 32 61 2.293703031022611 0.0218075625355373 14.597087378640778 57.060679611650485 -0.0519222534779674 0.4286122989812534 8.002292830543196 9.368077769293231 1.3877870839733877 0.3500560744701435 0.2543462020814974 1.0 0.8660036256713154 0.1276325422049128 0.0772729541655137 +Glycoside catabolic process 5 6 2.2931217969309525 0.0218409938173995 2.995145631067961 5.604368932038835 0.914408298188202 0.1915126053981477 1.4021397407455505 0.554137429771367 1.5051386650706404 0.245673751384095 0.0001254368379847 1.0 1.0 0.1781979724676324 0.0003311660608568 +Midbrain development 3 21 2.2894048840107497 0.0220558386349449 4.706310679611651 19.65776699029126 0.3119231503214399 0.579247250306076 2.8040641414388903 1.6166196495581584 0.8520585015288774 0.3176882217380689 0.1613833363765222 0.0295498589150116 0.002010543955723 0.0463117823544705 0.1352992013633588 +Aerobic respiration 16 85 2.282189282706476 0.0224781675660721 23.075242718446603 86.43446601941747 0.4685851027775424 0.4381258038241513 10.546552774557412 6.275478278783705 1.570513830163352 0.3792860784147517 0.0001058308528592 0.000105129297768 2.092466740997334e-05 0.0004779420673472 0.0002545584408594 +Regulation of regulated secretory pathway 5 18 2.279602704483937 0.0226312624190911 5.135922330097087 19.024271844660195 0.5532028818011353 0.482650154445206 2.517120190261048 2.8085156919839167 0.8466655843360735 0.3050640843792452 0.2731060960277088 0.2870659866655126 0.1454623761357323 0.5088214927290686 0.1243087546226736 +Protein exit from endoplasmic reticulum 12 22 2.276494149055221 0.0228164503999079 7.002427184466019 21.233009708737864 0.6943602976218084 0.4745028866201709 3.210645812910548 2.182026685495945 1.0430444956616387 0.3507892727806736 0.0785184637044285 1.0 0.3404254693467198 0.0854582473740603 0.0169717228577044 +Exocytosis 23 73 2.27501227030916 0.022905193766131 16.961165048543688 72.39563106796116 0.1685031958770574 0.7402195774784479 6.361172161168185 8.909538923258275 0.6212716645622243 0.2932215182854906 0.1073201859176334 0.6437166934391536 0.3336345205529002 0.4083303421168068 0.0152140749116865 +Amyloid precursor protein catabolic process 5 14 2.273909867162028 0.022971406317132 4.62621359223301 16.47087378640777 1.203006467000838 0.2754962460876 2.1329801006381106 2.1803683249886516 0.947433834000198 0.2709877848980267 0.0059141512909675 0.1913705796369965 0.0666692325567911 0.0040251974639471 0.018870184963526 +Atp synthesis coupled electron transport 8 35 2.265490874676721 0.0234825733769101 11.567961165048544 37.61407766990291 0.6403585631460136 0.4181082416574377 5.189865284224125 3.9859091462453993 1.417482213086961 0.3703097362636519 0.0026349128290207 0.0539251864958397 0.0390282143216565 0.0114270679899089 0.0013056967129913 +Proteoglycan metabolic process 6 9 2.2621651792760864 0.0236871997927181 3.0558252427184467 7.347087378640777 0.90943742591388 0.2775323863615319 1.813993622553226 2.3052106999156825 1.19959130355936 0.2714444012698452 0.488311524012292 1.0 0.0640285846884502 0.2797556636969028 0.0169717228577044 +Cytosolic calcium ion transport 8 21 2.261554344654616 0.0237249514801114 6.567961165048544 23.944174757281555 0.4634706877593821 0.4616211122842976 3.323605294530572 2.8902732844456565 1.0331628024603872 0.3216839736311487 0.0417308550900142 0.3371313972628795 0.0483217377147592 0.0551022953292233 0.0219681008445407 +Protein insertion into mitochondrial inner membrane 5 8 2.249268702340021 0.0244954057851909 2.45873786407767 5.665048543689321 0.6692509200083531 0.3406754428009103 1.501050234026552 1.645659707056692 1.2686438529444872 0.3125184360343283 4.815836726362641e-05 0.0561990347849709 0.0056684159955205 0.00262770885776 9.246798264487089e-06 +Neutral lipid metabolic process 8 13 2.2356377813228465 0.0253755076528925 3.7645631067961167 14.638349514563108 -0.2959545341177167 0.2756576316525815 2.469308018590983 2.835760748630011 1.4124950075268554 0.2284226385878861 0.2479132214230708 1.0 1.0 0.2210522410556178 0.1064321965715116 +Cellular homeostasis 49 131 2.210017543412903 0.027103944770642 35.03155339805825 140.69660194174756 0.4666088113804902 0.5685618966047314 11.62423291193178 14.777892439656425 1.1736922314243927 0.3887657095146841 0.0181209284720946 0.3323602521916406 0.1121711352136911 0.0145022138643312 0.0048607833128012 +L alpha amino acid transmembrane transport 8 11 2.2024143095241517 0.0276360560041841 4.480582524271845 10.533980582524272 0.7590361902351016 0.3223730555033793 2.606398335255894 1.1951807271273862 1.273814103695318 0.3116596719827348 0.3569461856507646 1.0 0.2732850813359189 0.1899587232036964 0.4819543230991074 +Protein insertion into er membrane 8 12 2.196402467740191 0.0280631491929141 4.451456310679611 12.691747572815531 0.9645901040516046 0.3077872373135509 2.16101217194965 1.431147904526304 1.1733171268605926 0.305304417896891 0.0486421772938398 1.0 1.0 0.0983610682747182 0.0201372619620155 +Neuron recognition 3 6 2.1936649398881545 0.0282595060901151 1.9368932038834952 6.189320388349515 0.7447638338644241 0.3705616592284931 1.1064234596616862 1.175429078554095 1.011644937344681 0.2892876339238009 0.2867073462023629 1.0 0.2372212797486779 0.1467432355955838 0.1533018949933901 +Peroxisome organization 9 12 2.1933652020956584 0.0282810773646238 4.286407766990291 11.196601941747574 0.606295801393023 0.4614466229190617 2.3307796330420754 2.613015983661412 0.9820420209440194 0.3193147518558685 0.1110967103239431 1.0 1.0 0.5329697587184232 0.0159032502878613 +Amyloid precursor protein metabolic process 8 17 2.190926394968984 0.0284571193122937 5.91747572815534 20.04368932038835 1.2306110398413417 0.2828388345239639 2.574706211328507 3.0661056512526157 1.0127867956133585 0.2841981221806073 0.017178201561234 0.2333020504203794 0.0978881295505725 0.0104048104957299 0.0497612217246468 +Regulation of amyloid fibril formation 0 5 2.174219298342844 0.0296886697323059 2.2888349514563107 5.662621359223301 0.5261836595996398 0.3490055624244857 1.4817896559260575 1.2503440001723864 1.197683561482515 0.297347360341851 0.3460587364794138 1.0 1.0 0.2365379696877526 0.4223814846322101 +Regulation of tor signaling 4 13 2.1479490109657977 0.0317178062919647 3.7257281553398056 15.856796116504857 0.5324264676599477 0.5062118127575728 2.457407704295241 3.8245981357757177 0.8332772576410542 0.3031574374448638 0.6053371835865897 1.0 0.5484830827387088 0.5946863363415549 0.7687270582276297 +Lipid biosynthetic process 59 143 2.1405809045925595 0.0323078500476312 38.012135922330096 141.7257281553398 0.5620793375816577 0.4367444072022249 15.729119254593195 17.314902336322657 1.553306672697969 0.3832082090559359 1.1749213439442068e-05 0.611897199111217 0.588351162326052 3.5907161093534725e-05 2.4039114387805057e-07 +Sarcoplasmic reticulum calcium ion transport 3 6 2.138990556907188 0.0324364331593525 1.9563106796116505 7.322815533980583 0.6468881172758483 0.4186906915304785 1.3230715882937036 1.363591714565082 0.9330202288701288 0.2915813242092217 0.0040574836292075 1.0 0.0126574737404708 0.0087554356838108 0.0098193480789534 +Positive regulation of mitochondrial translation 2 7 2.137128286851416 0.0325875588078887 1.8155339805825244 7.439320388349515 1.1233950947475233 0.2654033071264799 1.4295601388514203 1.5544197944414198 1.0052042080836443 0.2741718924063684 0.1085490453835639 0.0697581245313758 0.1349531130589082 0.0498779046475234 0.0336357980244025 +Regulation of anion transport 6 11 2.132722755693815 0.0329474760585086 3.657766990291262 11.50242718446602 0.7713855446015195 0.3761489496061844 2.0089273726107977 1.6987985280405251 0.9512307489218268 0.2850669663772418 0.3569461856507646 1.0 1.0 0.5553918894123164 0.4819543230991074 +Organelle membrane fusion 13 31 2.1218731835840257 0.0338483889145209 9.026699029126211 29.49271844660194 0.2503440438263548 0.5991935201964022 4.297974887399588 5.110663265938685 0.9179616425810708 0.3357137012753883 0.0417308550900142 1.0 1.0 0.6143274539738884 0.0026386753824796 +Organic cation transport 3 5 2.116429418777383 0.0343083022173362 2.191747572815534 5.524271844660194 1.626219676916526 0.1372808582950073 1.481153399412497 1.209546654977186 0.871004228766265 0.1892257790071234 0.0431830308522053 1.0 0.1837383274168749 0.4028006685093745 0.0171177319456962 +Isoprenoid metabolic process 12 25 2.1155313029848686 0.0343846898895956 6.351941747572815 23.436893203883496 0.371913197601784 0.4325927382253215 2.8701546111232905 3.133501725907374 1.111400072689174 0.3110459828013394 0.017178201561234 1.0 0.0978881295505725 0.0438041643494559 5.512316207184221e-05 +Macromolecule depalmitoylation 2 5 2.1128105558982924 0.034616985825328 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0091783194539023 0.0561990347849709 0.0056684159955205 0.0328731354880699 0.0181181417645757 +Endoplasmic reticulum unfolded protein response 8 20 2.112702484340191 0.0346262405312929 5.922330097087379 20.817961165048544 0.3028076268112233 0.5117002472852509 2.747246884507101 1.9665572199818449 1.041467084382159 0.3322997623752832 0.0527025609711632 1.0 1.0 0.3776649172031714 0.0461426336925489 +Protein processing 19 46 2.110293169514613 0.0348331115763904 12.08252427184466 45.980582524271846 0.9011703887478908 0.3916089016010577 4.43430858840224 4.931040148104543 1.176660792763282 0.3507158233798557 0.0023234747180014 1.0 0.7411972663513849 0.0066315031942502 0.0076511867354225 +L amino acid transport 7 11 2.101550356880236 0.0355926824085377 5.114077669902913 11.91504854368932 0.7755289387861473 0.3283794523692901 2.998235059113201 1.3256494094845783 1.3058948249973923 0.3189923022900864 0.37072767415641 1.0 0.2802926639431586 0.1988041978590851 0.4978168612908779 +Phosphatidylethanolamine metabolic process 3 5 2.0951732523062616 0.0361555940802149 1.4174757281553398 3.54126213592233 1.2136417130163286 0.2301275972070245 1.0265813928797825 1.052388111444633 1.16214154732605 0.2536389297154525 0.084681911188206 1.0 1.0 0.0382400085743442 0.0227185425065092 +Antigen processing and presentation 10 20 2.0947986741998457 0.036188893031952 6.201456310679611 22.17718446601942 0.8231471183465873 0.4220086818460768 2.970845032857872 3.056135613532617 0.9682333159777928 0.3245513416930483 0.063763674097226 1.0 0.4242240140575919 0.4035011436345253 0.1427791401704325 +Chemokine production 1 7 2.0856534383112018 0.0370100269889708 1.8810679611650485 8.337378640776699 0.9152793985046536 0.327029475914965 1.2820382835273771 1.4780796128991345 0.9350060766690576 0.2657366976150246 0.3430575480785555 0.1430638950507344 0.266209970857853 0.181169408752189 0.465786591734874 +Positive regulation of chemokine production 1 7 2.0856534383112018 0.0370100269889708 1.703883495145631 7.002427184466019 1.1308330497685224 0.261365768238967 1.2206493839204828 0.948936007151574 0.9251734036107908 0.2478284645013121 0.2157874462253757 0.1049896535105009 0.1993869387044997 0.1060727287920157 0.3089323218960526 +Carbohydrate derivative catabolic process 14 36 2.0774197963100143 0.0377628306414514 9.92233009708738 34.20388349514563 -0.0123085756499559 0.2707665028006943 3.843893961107642 3.291233496452993 1.7787241070250257 0.2878972939517332 0.001237105224407 1.0 1.0 0.020682535454445 0.009325311019984 +Cellular hormone metabolic process 9 18 2.0734481480609075 0.0381305919826102 5.441747572815534 17.32766990291262 0.9908884218524354 0.2940959275691314 2.8170777488519256 1.7185203072340225 1.2515909253444888 0.3031653223897966 0.0029001458316625 0.2183067054048652 0.08610744549237 0.0075944976014186 0.000693808475419 +Glycosaminoglycan catabolic process 4 5 2.0674132058311 0.0386952349424425 2.6432038834951457 4.665048543689321 0.5167433573606753 0.1777854895826483 1.1305026922003756 0.6751064263980151 1.6910244329591049 0.2288538535307848 0.0005400376352805 1.0 1.0 0.2365379696877526 0.00138858926748 +Aminoglycan catabolic process 4 5 2.0674132058311 0.0386952349424425 2.6893203883495147 4.728155339805825 0.5164809724591738 0.1764823388548578 1.1619294817897845 0.7656988020633148 1.69808407883546 0.2279588459746903 0.0007859772692858 1.0 1.0 0.2550529546148332 0.0020033682110678 +Antigen processing and presentation of exogenous peptide antigen 3 6 2.066634956788362 0.0387685642993986 1.6067961165048543 4.686893203883495 0.987028524507588 0.2895214995402835 1.1019631322504793 1.05964046762731 1.0509935492639806 0.2645206747413269 0.1740597032129271 1.0 1.0 1.0 0.2539261987860491 +Mitochondrial calcium ion transmembrane transport 6 9 2.064258427278575 0.0389932204267955 3.4684466019417477 9.04126213592233 0.7792467211325117 0.2463779000555085 2.196969341156949 1.2010296388602075 1.3738174116662032 0.263849842646199 0.0208873878301334 0.0742352733278267 0.0100519320580488 0.0561137872346343 0.00630824692371 +Regulation of mitochondrial gene expression 2 11 2.063399627366835 0.0390746753341995 2.594660194174758 11.4247572815534 0.8803116051858394 0.3443222138925089 2.2226265034531534 1.9350293365530056 0.991093358800792 0.2980671372776958 0.2725008929400679 0.1221118561195742 0.2297987482657219 0.1383652025719425 0.14168603717257 +Proteoglycan biosynthetic process 5 8 2.054616553484396 0.0399160555248785 2.6432038834951457 6.677184466019417 0.8965384350791714 0.2873226841395866 1.6239641738792057 1.992745053805788 1.1569297556833695 0.2755887487741971 0.3843902298869345 1.0 0.0443091130960601 0.2076979954646016 0.0259406914165302 +Mucopolysaccharide metabolic process 6 10 2.051476598779741 0.0402205562595121 3.400485436893204 8.912621359223301 0.5894446998893683 0.2689339883290864 1.6227448151896249 1.7256308603927724 1.433353391777711 0.275728271795533 0.0894994943186356 1.0 0.3530974878629287 0.2978006616879862 0.0056200963406339 +Regulation of ryanodine sensitive calcium release channel activity 2 5 2.0512593709612807 0.0402416948437298 1.8810679611650485 5.526699029126213 0.1285747015933797 0.5026980454113974 1.3663539553511053 1.0435961800842488 1.0131494032924555 0.3179171202162478 0.0174514302411212 1.0 0.1349531130589082 0.0051503840765812 0.0336357980244025 +Sterol biosynthetic process 9 24 2.0429186996057345 0.0410604868792634 7.281553398058253 24.52912621359223 1.190088798384403 0.3136799329736269 3.292879861326439 2.61838648411319 1.1232845583768152 0.3105481837594456 0.001793152047592 1.0 1.0 0.0008884443610078 6.895819454254321e-05 +Alcohol biosynthetic process 13 36 2.0365073007293795 0.04169944074769 9.344660194174756 36.09466019417476 1.0726679306851277 0.3539682718575088 3.792896481514287 3.1078151772256564 1.1587776417647702 0.3419459456532639 0.0017445884165693 1.0 0.5741114914523541 0.0002679145729267 8.056907748559596e-05 +Regulation of exocytosis 14 37 2.034326435586695 0.0419186935227233 8.864077669902912 39.16019417475728 0.1036096249992311 0.7254597910393834 4.068702576271896 4.34423711125452 0.6304811118238788 0.2835648818538584 0.1598213753310193 0.4354616437047781 0.3139585525038253 0.5480114911468156 0.1205470075659955 +Cellular transition metal ion homeostasis 5 20 2.0312144644642216 0.0422332437176835 5.893203883495145 20.42233009708738 0.9608801516152976 0.3243056832171095 2.800529150274697 2.6932649561537056 1.130076157725316 0.3011842711337114 0.2314152963044024 0.2695684389372801 0.1290920553826253 0.0723728978816966 0.0953101243725822 +Transition metal ion homeostasis 4 24 2.0280280619573774 0.0425573840510054 6.640776699029126 24.57281553398058 0.9239194315613378 0.3015424973151205 2.934079531592402 2.8081087224394015 1.2471169312381896 0.2974369333820005 0.1856593962790382 0.0564048148733258 0.0415809882988902 0.0444212272681039 0.0936686726213597 +Signal peptide processing 2 5 2.0180801551006406 0.043582914099749 2.0898058252427183 5.155339805825243 0.788498872885968 0.2357910477072221 1.2938213743418876 0.7208043181852656 1.3841109341751536 0.2490116896927748 0.0070802339077876 1.0 1.0 0.0020064706347618 0.0140894483762481 +Inorganic anion transmembrane transport 7 8 2.017419267968467 0.0436517781879695 3.4101941747572817 8.983009708737864 1.1245392058053427 0.2357455210082705 2.3748669786284156 1.7214248641786654 1.1968417731555627 0.2697184972505711 0.3008835791389011 1.0 0.2445730022705269 0.1552222190730896 0.1652047572335966 +Mitochondrial calcium ion homeostasis 6 10 2.007493297150779 0.0446971636291131 4.62621359223301 10.509708737864075 0.2790428491871666 0.3774917598770124 2.1634860921400008 1.7383182679254283 1.294226020505384 0.3175561312397286 0.0431830308522053 0.0963063052639835 0.1837383274168749 0.4028006685093745 0.0171177319456962 +Regulation of er to golgi vesicle mediated transport 5 6 2.001283867052339 0.0453618073242634 2.1966019417475726 5.915048543689321 0.8267152021532312 0.3699978591289015 1.4151359695885812 0.8244249231762646 0.9890575089615372 0.3183740962504898 0.084681911188206 0.0607401038440192 0.1180585699575878 0.2731207001200411 0.129364196063302 +Protein maturation 26 68 2.00035637749666 0.0454617952771752 16.635922330097088 69.29611650485437 0.7279397561088901 0.5092233260742579 5.6828366082703345 6.923625268615643 1.0037762420957868 0.3621314209884535 0.0016180004892059 0.6239158458722325 0.5790998686136157 0.0035721060761345 0.0091177603064653 +Sensory perception of light stimulus 8 14 1.981873527422984 0.0474933974825977 5.009708737864078 15.96359223300971 0.918103407248628 0.3572194322029593 2.4583724414330383 3.147064390877318 0.9947617981182544 0.3055434177582076 0.239630929796809 0.2731012734555347 0.4724360815693985 0.2146915796551673 0.2171967394237606 +Peroxisome fission 4 5 1.979891597322284 0.0477157107963641 1.6019417475728157 3.9805825242718447 0.8016205424992385 0.3969435702023293 1.0505643959342583 1.2086306343048052 0.9137030061633076 0.3025779217908124 0.0344070214130163 1.0 1.0 0.1781979724676324 0.0003311660608568 +Cellular respiration 17 100 1.972109331836162 0.0485971269040392 27.975728155339805 102.1019417475728 0.3887198796668061 0.4496840882999475 12.70690482749566 7.191843824002275 1.6294784865611704 0.3894421445164553 9.726785696673968e-05 2.9922625081161225e-05 1.2864604404953175e-05 0.00019906057211 0.0003386551397025 +Lipoprotein localization 4 5 1.971096211569356 0.0487128719909932 1.7451456310679612 4.762135922330097 1.33870340128666 0.2150435313503844 1.1193794779630346 1.3835803073772095 0.999398972942542 0.2555578059866495 0.0734387458229045 1.0 0.0056684159955205 0.0328731354880699 0.0181181417645757 +Chloride transport 8 11 1.964456079748532 0.0494772248492942 4.33252427184466 12.12621359223301 1.0302584084066435 0.2341882174183942 2.3624510960969567 2.26059366569241 1.2797232968088257 0.2563105728143979 0.1277836657156577 0.1471951297158956 0.0398064357050217 0.0449350347407693 0.0743636419116672 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ed9b3287542732c14218ef3008387eabbc5f8d6a --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 6356, + "title": "Average number of proteins per term", + "value": 18.536028949024544 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6f982a33fd3b4209c00cd91e3b25fd482f0b0a3f --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bd9c1716ded663997ebcfa0f506ed6ab6affd853 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1615 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial transport 0.5758975358300011 4.423175211105992 9.726080139493831e-06 0.0599472290606745 0.0303030909474051 83 O43464,Q9NS69,Q8N4H5,O60220,Q99595,P05141,P23786,O60830,Q9UJZ1,Q8N8Q8,Q10713,P00846,O00165,Q14849,Q9P0J0,Q9HAV7,Q9GZY8,P52789,P24539,P62072,P51572,P45880,P12235,Q53H12,O43615,Q6NUK1,O14737,Q15388,O14925,Q9Y512,O95429,Q9UBX3,Q99797,Q15070,P50416,Q9Y584,Q3ZCQ8,P06576,O75964,P56385,Q5JRX3,P56134,Q9UJS0,O96008,Q9Y5J9,Q9Y371,P55786 47 +Membrane lipid metabolic process 0.7231869412697285 4.352294839361279 1.3471991984426168e-05 0.0820648722961413 0.0303030909474051 39 Q5H8A4,Q96G23,Q99735,P07602,Q9NZJ7,Q9H2C2,Q8NBX0,Q06136,P50897,Q9NZ01,Q9NXE4,P06280,P16278,Q99805,O95470,Q8NCC3,Q53H12,P17900,O15269,P04062,Q13510,P04066,Q9P035,Q92643,O60762,Q96S52,Q05655,P06865 28 +Anion transport 0.6335882191335381 4.33915892502044 1.4302906362839709e-05 0.0869000434836295 0.0303030909474051 65 Q14728,Q15907,Q9HC21,P05141,P07602,Q9NZJ7,Q9UHG3,P12236,O43826,Q9H2D1,Q00325,P28288,O43808,Q9C0H2,P12235,P45880,Q6NUK1,O00400,Q08722,O60831,Q99808,Q9UBX3,P54105,O43681,Q9H936,Q9Y619,Q86WC4,P51790,P21796,Q15041,Q9UJS0,Q02978,Q9NP80,Q9Y277,Q7L0J3,Q96S66,Q15042,P04083,Q8TDW0,Q8TB61,P55011 41 +Nitrogen compound transport 0.3872483531141122 4.217419042048877 2.4711449658099127e-05 0.1453539862004771 0.039266493506721 553 Q86Y82,P98194,P43307,Q9NS69,Q8N4H5,Q9UGP8,Q99595,P49755,O60830,O60725,O75396,P18031,Q9H2D1,P50402,P57105,Q5JRA6,P50897,Q9HCU5,P41208,Q53FT3,Q9BSK2,P24390,Q9Y282,P62072,P51572,Q9P2W9,O43615,O00400,Q9Y3B3,Q9BW27,O14925,Q15070,Q99797,Q15005,Q5T9L3,Q676U5,A6NIH7,P61019,Q9Y584,P50416,Q9HD47,Q3ZCQ8,O43592,O15127,Q8NFH5,Q96GC9,Q15363,Q9Y619,P10619,O95721,Q15041,Q9UHB9,Q9H4A6,Q9Y3A6,Q9H9E3,P67809,Q96PC5,Q12907,Q9UJS0,Q8NEB9,Q92945,Q12769,O43752,Q9Y277,O15173,O95070,Q9Y371,Q96P70,Q15042,Q8TCT9,Q15629,P55011,Q9BUN8,Q15907,O43464,Q99623,Q15904,Q9NZJ7,Q9Y6B6,Q6NUQ1,Q15154,P12236,Q8N8Q8,P40616,O00165,Q14168,Q9HAV7,Q8WUM4,Q8TEX9,P12235,P46379,Q9HD20,Q08722,O14737,Q96RL7,P27105,P40939,Q15388,O60831,O00560,P53680,O14579,O95429,Q92544,O43681,Q9H936,O43731,Q8N5M9,Q07666,P49458,Q99523,Q9HAV4,Q5JRX3,Q9Y2T2,Q9Y5M8,P40855,Q969Q5,O75915,Q9Y5J9,Q9BTX1,O95373,Q05655,Q9H9H4,Q96D46,P50542,Q06787,P60604,O95831,O15126,Q8TB61,Q16836,Q16850,Q9HC21,O60220,P07602,Q96ST2,L0R6Q1,Q8WVM8,P31751,O60784,Q14108,Q8N183,Q9C0E2,P57740,Q10713,P55060,P51991,O14617,Q9NRG9,Q8NE86,Q9NR31,Q9P0J0,O95140,O43633,P16870,O14828,Q6NUK1,P61026,Q03518,Q99808,O75381,Q13190,Q9Y5U9,Q96PU8,Q8NFH4,O15155,O95249,Q96L92,Q96KC8,Q13277,Q7L0J3,P04083,P55786,Q8TDW0,Q7Z4Q2,P05141,Q6P4A7,P27824,O15397,Q9UBV2,O43808,Q9GZY8,Q92973,Q53H12,Q8TBQ9,Q9UEU0,Q9Y512,Q8N1F7,P52292,O15400,O15260,P56962,Q4J6C6,Q07820,O14653,Q7Z3B4,O00429,Q9P253,P22626,Q08211,O96008,O75027,P49321,Q99442,Q9Y5Y5,Q9H0U4 206 +Mitochondrial transmembrane transport 0.6619536894254595 4.154611323239539 3.258409484052649e-05 0.1870680546837483 0.0404984042326671 49 Q9H4I9,P05141,Q99595,Q6P4A7,P23786,O60830,P12236,Q9UJZ1,Q9H2D1,P00846,Q00325,Q9BPX6,Q9BSK2,Q9HAV7,P24539,P12235,O43615,Q15388,O14925,P50416,Q9H936,Q3ZCQ8,O75964,Q9Y619,P21796,P56385,P56134,Q8IYU8,Q9UJS0,O96008,O95202,O75027 32 +Mitochondrial respiratory chain complex assembly 0.6815823113019267 4.101724540586866 4.100822913266633e-05 0.2294522465162101 0.0404984042326671 40 Q6DKK2,Q86Y39,Q9Y2R0,O96000,Q96E52,Q8N8Q8,O75880,Q9P0J0,Q9BSK2,O75438,Q96I36,Q9Y512,Q15070,Q9H061,P03886,O43676,O75306,Q96CU9,Q69YU5 19 +Organic anion transport 0.6650470144757953 4.068182583419147 4.7381249062894426e-05 0.2600423719567774 0.0404984042326671 43 Q14728,Q9HC21,P07602,P05141,Q9NZJ7,P12236,Q9H2D1,P12235,Q6NUK1,O00400,Q08722,O60831,Q9UBX3,Q99808,Q9Y619,Q9NP80,Q7L0J3,P04083,Q8TDW0,Q8TB61 20 +Carbohydrate derivative transport 0.849099304649778 3.990872043037206 6.583079243482892e-05 0.3419236294968477 0.0404984042326671 19 Q9HC21,P05141,P07602,L0R6Q1,Q9NZJ7,P12235,P12236,Q6NUK1,O00400,Q08722,O43826,Q99808,Q8TDW0,Q8TB61,P61916,Q8WTV0 16 +Sphingolipid metabolic process 0.7425276787914784 3.968926597528865 7.219711506856186e-05 0.3680224636738874 0.0404984042326671 29 Q96G23,P07602,Q9NZJ7,Q9H2C2,Q06136,P50897,Q9NZ01,P06280,P16278,Q99805,O95470,Q8NCC3,P17900,Q53H12,O15269,P04062,Q13510,Q9P035,Q05655,P06865 20 +Protein localization to mitochondrion 0.6118489846011886 3.96206677430272 7.430375133221645e-05 0.3764287151379857 0.0404984042326671 59 O43464,Q9NS69,Q8N4H5,O60220,Q99595,O60830,Q8N8Q8,Q10713,Q9Y6C9,O00165,Q9P0J0,Q9HAV7,Q9GZY8,P52789,Q53H12,P62072,P51572,O43615,O14737,Q15388,O14925,Q9Y512,Q15070,Q99797,Q9Y584,Q3ZCQ8,P0DP25,O00429,Q5JRX3,O96008,Q9Y5J9,Q9Y371,P55786 33 +Mitochondrial membrane organization 0.6355088327851977 3.955709797202021 7.630774769529225e-05 0.3843216127323859 0.0404984042326671 50 Q9NS69,O60220,P05141,Q96E52,Q8N8Q8,Q9P0J0,Q9H3K2,P52789,Q53H12,P62072,P12235,P45880,P17152,Q9BUR5,O14737,Q9Y512,Q15070,Q9Y584,O60313,P0DP25,Q13505,Q16891,O95202,Q9Y5J9,Q5XKP0 25 +Anion transmembrane transport 0.6781392505577519 3.955232767832701 7.646017161611063e-05 0.3849178425994763 0.0404984042326671 38 Q14728,Q9HC21,P05141,Q9UHG3,P12236,O43826,Q9H2D1,Q00325,O43808,P12235,P45880,P08183,O60831,Q9UBX3,Q8N697,Q9H936,P51798,Q9Y619,P08195,P51790,P21796,Q15041,Q9UJS0,Q02978,O75915,Q9Y277,Q8TDW0,Q8TB61,P55011 29 +Cellular ion homeostasis 0.5265110301392958 3.899535740179232 9.63773106252841e-05 0.458062017411302 0.0466724834001532 82 P98194,Q9H4I9,Q15904,P09601,P20020,Q9UJZ1,O75880,P50897,P62942,Q9BPX6,Q96A33,P51572,Q9HD20,Q96PU5,Q96HE7,Q9P246,Q9UM00,Q92544,O75503,O76024,P0DP25,P54709,P06576,P16615,Q93050,Q8N511,Q9Y487,Q96TC7,Q9HC07,Q8IYU8,P78417,Q16891,O95202,O75027,P05023,Q7L0J3,Q9Y639,P05067,P55011 39 +Establishment of protein localization to membrane 0.5294230882581575 3.8838796045643944 0.0001028028268725 0.4797513228059455 0.0466724834001532 88 Q15907,P98194,P43307,Q9NS69,Q9UGP8,Q15904,O60220,P31751,O60725,Q8N8Q8,Q9NPA0,Q9P0J0,Q96A33,Q9H8Y8,Q9GZY8,Q53H12,P62072,P46379,Q9HD20,O14737,P61026,P27105,Q15006,Q9Y512,O00560,Q15070,O43681,Q4J6C6,Q9Y584,P0DP25,P49458,Q15041,Q9H4A6,Q9UHB9,P40855,Q9Y5J9,Q13277,Q9H9H4,Q99442,P50542,Q8N4V1,Q9Y5Y5,Q15042,Q15629,O15118 45 +Protein targeting 0.5300448199896775 3.7507382687309234 0.0001763146697215 0.6739664035773625 0.0734580562536458 107 O43464,P43307,Q9NS69,Q9UGP8,Q8N4H5,Q99595,O60220,P31751,O60830,O60725,Q14108,Q10713,P57105,O14617,O00165,Q9P0J0,Q9HAV7,Q9GZY8,Q53H12,P62072,P51572,P46379,O43615,Q96RL7,O14737,P27105,Q15388,O14925,O00560,O95429,Q9Y512,Q99797,Q15005,O75381,O43681,Q9Y584,Q3ZCQ8,Q7Z3B4,P49458,Q99523,Q15041,Q9UHB9,Q5JRX3,Q9Y2T2,Q9Y5M8,P40855,P55786,O96008,Q9Y5J9,Q9H9H4,Q99442,Q9Y371,P50542,Q9Y5Y5,O95831,Q15629 56 +Endoplasmic reticulum organization 0.6205416047609277 3.738778665024379 0.0001849164411671 0.6913161244620295 0.0734580562536458 45 Q6NUK4,Q5JRA6,Q9NPA0,O95197,Q9NXE4,Q96A33,P57088,P46379,Q9P2W9,P61026,Q15006,Q9NQC3,Q8N5M9,O14657,Q00765,Q15363,Q12981,O00429,Q15041,Q8N4V1,Q12907,Q8NHH9,Q9H6H4,Q15042,Q15629 25 +Nucleotide transport 0.8634743932465696 3.6504982628667983 0.0002617320796669 0.8105796844019997 0.0971492753541729 14 Q9BSK2,Q9HC21,P05141,P12235,P12236,Q6NUK1,O00400,Q08722,Q9H2D1,Q8TDW0,Q8TB61,Q99808 12 +Protein targeting to mitochondrion 0.6065356133629951 3.637270987970054 0.0002755419948587 0.8265014866449529 0.0971492753541729 46 O43464,Q9NS69,Q8N4H5,O60220,Q99595,O60830,Q10713,O00165,Q9P0J0,Q9HAV7,Q9GZY8,Q53H12,P62072,P51572,O43615,O14737,Q15388,Q9Y512,O14925,Q99797,Q9Y584,Q3ZCQ8,Q5JRX3,O96008,Q9Y5J9,Q9Y371,P55786 27 +Organophosphate ester transport 0.6976961867916351 3.6237088769263313 0.000290408469435 0.8421490912376826 0.0971492753541729 28 Q9BSK2,Q9HC21,P05141,P12235,Q96GC9,Q14108,P12236,Q6NUK1,O00400,Q08722,O43826,Q9H2D1,Q99808,Q05655,Q8TDW0,Q8TB61,P61916,Q8WTV0 18 +Metal ion homeostasis 0.5225562948931372 3.5696129401421297 0.0003575090630738 0.8969698783797678 0.1100722170952301 74 P98194,Q9Y6N1,P20020,P09601,Q9H4I9,Q15904,Q9UJZ1,O75880,P62942,Q9BPX6,Q96A33,P30519,P51572,Q9HD20,Q96PU5,Q96HE7,Q9P246,Q9UM00,O76024,P0DP25,P16615,Q8N511,Q9Y487,Q96TC7,Q8NE01,Q9HC07,Q8IYU8,P78417,Q16891,O95202,O75027,P05023,Q7L0J3,Q9Y639,P05067,P55011 36 +Inner mitochondrial membrane organization 0.7179103040975597 3.533736070500465 0.0004097300046206 0.926080422963981 0.1183747231531253 24 Q9P0J0,Q13505,Q9H3K2,Q9Y584,O60220,O60313,Q53H12,P62072,P17152,Q16891,O95202,Q9Y5J9,Q96E52,Q9BUR5,Q9Y512,Q5XKP0 16 +Transmembrane transport 0.5450775040470917 3.4868938526892324 0.0004886652671014 0.9552523151829402 0.1350415842476882 202 P98194,Q9NS69,Q9UGP8,Q9H4I9,P49755,Q99595,O60830,Q9UDW1,Q9H2D1,P00846,Q00325,Q9BSK2,Q9C0H2,P24539,P45880,O43615,O00400,Q96PU5,O14925,O75844,Q9UBX3,Q70HW3,Q99797,P50416,Q9Y584,Q9HD47,Q3ZCQ8,P0DP25,O75964,Q96GC9,Q9Y619,O14548,P21796,Q15041,Q9HC07,P56134,Q9UJS0,P78417,Q9Y277,Q9H2V7,Q15629,P55011,P05067,Q99623,Q9BVC6,P20020,P23786,Q9UHG3,P12236,Q9UJZ1,P62942,P28288,Q9BPX6,Q9HAV7,P12235,Q96ES6,Q9HD20,P04062,P27105,Q15388,O60831,P13073,Q9UM00,Q9H936,P54709,P06576,P51790,Q99523,Q8WTV0,Q8NE01,P38435,Q02978,O75915,P50542,Q06787,Q8N4V1,Q8TB61,Q13423,Q14728,Q9HC21,L0R6Q1,Q7KZN9,P52789,Q6NUK1,Q03518,Q99808,O75381,P16615,P56385,Q8IYU8,Q7L0J3,Q8TDW0,P05141,Q6P4A7,O43826,O43808,Q9H0U3,Q96HE7,Q9P246,Q07820,O96008,O95202,O75027,P05023,Q99442,Q9Y5Y5 106 +Ion transmembrane transport 0.5211240623045825 3.404963934914252 0.0006617279242462 0.9851140117679144 0.1610341023475516 147 Q14728,Q99623,P98194,Q9BVC6,Q9HC21,Q9H4I9,P20020,P05141,P55011,Q6P4A7,Q9UHG3,P12236,Q9UJZ1,Q9UDW1,Q9H2D1,P00846,Q7KZN9,Q00325,O43826,P62942,O43808,Q9BPX6,Q9H0U3,Q9C0H2,P24539,P12235,P45880,Q96ES6,Q9HD20,O00400,Q96PU5,P27105,O60831,Q96HE7,P13073,O75844,Q9UBX3,Q70HW3,Q9UM00,Q9P246,Q9H936,Q9HD47,P0DP25,P54709,P06576,O75964,Q96GC9,P16615,Q9Y619,O14548,P21796,P56385,Q15041,Q9HC07,P56134,Q8IYU8,Q9UJS0,P78417,O95202,O75027,Q9Y277,P05023,Q8N4V1,Q8TDW0,Q8TB61,Q13423,P05067 67 +Cytochrome complex assembly 0.8155605734799867 3.3957303597833017 0.0006844575096716 0.9871177057252024 0.1610341023475516 14 Q9BSK2,Q6DKK2,Q9Y2R0,Q69YU5,Q8N8Q8,Q7KZN9,O75880,Q96I36,Q15070 9 +Protein insertion into membrane 0.6593897898724781 3.3923363364160135 0.0006929931795829 0.9877984410933704 0.1610341023475516 29 Q9P0J0,Q96A33,Q9NS69,Q9Y584,O60220,Q53H12,P62072,Q9Y5J9,O14737,Q8N8Q8,Q15006,Q8N4V1,Q15629,Q15070 14 +Glycoprotein biosynthetic process 0.5637685020564335 3.3869691193138407 0.0007066934182409 0.988816672850924 0.1610341023475516 53 Q86YN1,O43505,Q96L58,Q86SQ9,O43909,Q9BV10,Q9BT22,Q9H0U3,Q99805,Q8NCH0,P15291,Q6ZXV5,P35610,Q10471,Q9NRB3,Q9H4A6,Q92542,P46977,Q7LGA3,Q9HC07,P04844,Q9BXS4,O60762,Q10472,O15118 25 +Ion homeostasis 0.4918300704920101 3.385919720984996 0.0007094013319275 0.9890076417462308 0.1610341023475516 97 P98194,Q9H4I9,Q15904,P09601,P20020,Q9Y6N1,Q9UJZ1,O75880,P50897,P62942,Q9BPX6,Q96A33,P30519,P51572,Q9HD20,Q96PU5,Q96HE7,Q9P246,Q9UM00,Q92544,O75503,O76024,Q9HD47,P0DP25,P54709,P06576,P16615,Q93050,Q8N511,Q9Y487,Q96TC7,Q8NE01,Q9HC07,Q8IYU8,P78417,Q16891,O95202,O75027,P05023,Q7L0J3,Q9Y639,P05067,P55011 43 +Protein transmembrane transport 0.6814705695293043 3.363899632693984 0.0007684948537427 0.9924516865860498 0.1628184430129645 25 Q9NS69,Q9UGP8,P49755,Q99595,O60830,Q9HAV7,O43615,Q15388,O14925,O75381,Q9Y584,Q3ZCQ8,Q07820,O96008,Q99442,Q9Y5Y5,P50542,O95831,Q15629 19 +Establishment of protein localization to mitochondrial membrane 0.7382974022997153 3.34169132591725 0.0008326960605575 0.9949824873456374 0.1706789137404606 19 Q9P0J0,Q9NS69,Q9Y584,O60220,P0DP25,Q53H12,P62072,Q9Y5J9,O14737,Q8N8Q8,Q15070 11 +Membrane lipid biosynthetic process 0.6875504099754606 3.332950506457572 0.000859302271821 0.9957637346913736 0.1706789137404606 24 Q9P035,Q9NXE4,Q5H8A4,Q92643,Q96G23,Q99805,O95470,Q53H12,O60762,Q8NBX0,O15269,P04062,Q05655,Q13510,Q06136 15 +Inorganic ion transmembrane transport 0.490299923082801 3.2991661895239464 0.0009697248321911 0.9979015608043534 0.1867748798002116 106 Q99623,P98194,Q9H4I9,P20020,P05141,P36543,Q9UHG3,Q9UJZ1,Q9UDW1,O43826,P00846,Q7KZN9,Q00325,Q8NE86,P62942,Q9BPX6,Q9H0U3,P24539,P12235,Q96ES6,Q9HD20,O00400,Q96PU5,P27105,Q96HE7,P13073,Q9P246,Q9UBX3,Q9UM00,Q9H936,Q9HD47,P0DP25,P54709,P06576,O75964,Q96GC9,P16615,O14548,P51790,P21796,P56385,Q8N4V1,Q9HC07,P56134,Q8IYU8,P78417,Q02978,O95202,O75027,P05023,Q06787,Q13423,P55011 53 +Endoplasmic reticulum to golgi vesicle mediated transport 0.5090759061848272 3.286748476412095 0.0010135131515924 0.9984118036359096 0.1894673409271124 70 P49755,Q96RQ1,Q9Y6B6,O75396,Q5JRA6,Q9HCU5,Q9NR31,P24390,Q9Y282,P51572,Q9P2W9,Q9Y3B3,O14579,Q13190,Q9Y5U9,P61019,P56962,O43731,Q9HD47,O14653,Q15363,O15155,O95249,Q9Y3A6,Q96PC5,Q12907,Q8NHH9,O95070,Q9H0U4 29 +Lytic vacuole organization 0.7046816327256858 3.2489880583544486 0.0011581634007906 0.9993673243421316 0.1936899809049819 21 Q9HC07,P11117,P54802,Q14108,O14773,P10253,P04062,Q8N511,P50897,O75503 10 +Glycoprotein metabolic process 0.5277317310929456 3.246937171791453 0.0011665413838028 0.99940017048442 0.1936899809049819 62 Q86YN1,O43505,Q96L58,Q86SQ9,O43909,Q9BV10,Q9BT22,Q9H0U3,Q99805,Q8NCH0,P15291,Q6ZXV5,P35610,O00754,Q9NX62,Q10471,Q9NRB3,Q9H4A6,Q92542,P46977,Q7LGA3,Q9HC07,P04844,Q9BXS4,O60762,Q10472,Q9H0U4,O15118 28 +Cation transmembrane transport 0.4886681518291821 3.23592500756585 0.001212492342296 0.9995522507558836 0.1936899809049819 112 Q99623,P98194,Q9HC21,Q9H4I9,P20020,P05141,Q9UJZ1,Q9UDW1,P00846,Q7KZN9,Q00325,P62942,Q9BPX6,Q9H0U3,P24539,P12235,Q96ES6,Q9HD20,O00400,Q96PU5,P27105,Q96HE7,P13073,Q9P246,Q9UM00,Q70HW3,Q9H936,Q9HD47,P0DP25,P54709,P06576,O75964,Q96GC9,P16615,Q9Y619,O14548,P21796,P56385,Q9HC07,P56134,Q8IYU8,P78417,O95202,O75027,P05023,Q8N4V1,P05067,Q13423,P55011 49 +Divalent inorganic cation homeostasis 0.5544118174857164 3.2296747624568516 0.0012393111237367 0.9996225024970375 0.1936899809049819 49 P98194,Q9H4I9,P20020,Q9UJZ1,P62942,Q9BPX6,Q96A33,P51572,Q9HD20,Q96HE7,Q9P246,O76024,P0DP25,P16615,Q96TC7,Q8NE01,Q9HC07,Q8IYU8,P78417,Q16891,O95202,Q7L0J3,Q9Y639,P05067 24 +Organic acid transmembrane transport 0.6415439614890018 3.2273520887404405 0.0012494161763851 0.9996460144060836 0.1936899809049819 28 P31751,P23786,Q9H2D1,P53007,P28288,P08183,O60831,Q9UBX3,Q8N697,P50416,Q9H936,Q9Y619,P08195,Q15041,Q9UJS0,Q02978,O75915,Q15758,P11166,Q8TDW0 20 +Purine nucleotide transport 0.8608167958414201 3.209637385656824 0.0013290251707789 0.9997867194857648 0.1964484647783927 11 P05141,P12235,P12236,Q6NUK1,O00400,Q08722,Q8TDW0,Q8TB61,Q99808 9 +Ceramide metabolic process 0.7150601774211731 3.198882368861841 0.0013796144779918 0.9998454331692048 0.1992915823208216 19 P06280,Q96G23,Q99805,O95470,Q8NCC3,P17900,Q53H12,O15269,P04062,Q05655,Q13510,P06865 12 +Liposaccharide metabolic process 0.737238657300763 3.192392800417306 0.0014109930844665 0.9998734160821776 0.1992949343304341 17 Q92643,Q5H8A4,P06280,P16278,Q99805,P04066,P17900,O60762,Q8NBX0,Q05655,P04062,P06865 12 +Golgi organization 0.5253973795669356 3.174666441036281 0.0015000883200566 0.9999282067332504 0.2072730730930462 60 O75122,P49755,O75396,P40616,Q53FT3,Q9BTU6,Q9P2W9,Q9UEU0,Q9Y3B3,Q5T2E6,P48729,O15260,P61019,P56962,Q13190,Q96GC9,Q15363,O15155,Q9H4A6,Q9Y3A6,Q7Z3D4,Q9H9E3,Q12907,Q8NHH9,Q8TBA6,O43752 26 +Glycosylation 0.5538961497853664 3.165186115480062 0.0015498378076186 0.9999476945794454 0.2095908320260439 45 Q86YN1,O43505,Q96L58,Q86SQ9,O43909,Q9BV10,Q9BT22,Q9H0U3,P04062,P15291,O75503,Q6ZXV5,Q10471,Q9H9E3,P46977,Q9HC07,P04844,Q9BXS4,Q10472,O15118 20 +Carboxylic acid transport 0.6146046408331305 3.1391247834681963 0.0016945327221196 0.999979179776163 0.2243843746206721 31 P07602,Q9NZJ7,Q9H2D1,P28288,O60831,Q9UBX3,Q8N697,Q9H936,Q9Y619,P08195,Q15041,Q9UJS0,Q02978,O75915,Q8TDW0,Q9NP80,Q7L0J3,P04083,Q15042,P55011 20 +Membrane lipid catabolic process 0.7995296621246597 3.061180541288435 0.0022046611404793 0.9999991916702188 0.2374193705072396 12 Q9NXE4,P06280,Q99735,O95470,P17900,Q05655,P04062,P06865,Q13510,P50897 10 +Sphingolipid biosynthetic process 0.723906221993464 3.031530332567517 0.0024331747220485 0.9999998114879576 0.2374193705072396 16 Q9P035,Q96G23,Q99805,O95470,Q53H12,Q05655,P04062,O15269,Q13510,Q06136 10 +Ion transport 0.5050850764835377 3.0009853640281294 0.0026910749931599 0.999999963557448 0.2374193705072396 197 P98194,Q9H4I9,Q9UDW1,Q9H2D1,P00846,Q00325,Q9C0H2,P24539,P45880,O00400,Q96PU5,O75844,Q9UBX3,Q70HW3,Q9HD47,P0DP25,O75964,Q96GC9,Q9Y619,Q86WC4,O14548,P21796,Q15041,Q9HC07,P56134,Q9UJS0,P78417,Q9NP80,Q9Y277,Q96S66,O15173,Q15042,P55011,P05067,Q15907,Q99623,Q9BVC6,P20020,Q9NZJ7,Q9UHG3,P12236,Q9UJZ1,P62942,P28288,Q9BPX6,P12235,Q96ES6,Q9HD20,Q08722,P27105,O60831,P13073,Q9UM00,O43681,Q9H936,P54709,P06576,Q8NE01,Q8N4V1,Q8TB61,Q13423,Q14728,Q9HC21,P07602,Q7KZN9,Q6NUK1,Q99808,O76024,P16615,P56385,Q8IYU8,Q7L0J3,P04083,Q8TDW0,P05141,Q6P4A7,O43826,O43808,Q9H0U3,Q96HE7,Q9P246,P54105,O00429,O96008,O95202,O75027,P05023 87 +Mitochondrion organization 0.5023219591671365 2.9955340643971136 0.0027396469918707 0.9999999732596704 0.2374193705072396 188 Q9NS69,Q8N4H5,Q99595,Q9Y2R0,O60830,P14406,Q9BSK2,P62072,P51572,P45880,Q5T9A4,O43615,Q9BUR5,O14925,Q9NVT9,Q9NVI7,Q99797,Q15070,Q9H061,Q9Y584,Q3ZCQ8,P0DP25,Q96A26,O43676,O14548,P21796,Q9H4A6,Q13505,O14965,Q96CU9,Q69YU5,Q9Y371,Q9NUQ9,Q5XKP0,O43464,Q99623,Q86Y39,Q9UG56,Q9UJZ1,Q8N8Q8,Q9Y6C9,O00165,Q9HAV7,Q9H3K2,P12235,Q96RL7,O14737,P04062,Q8IWA4,Q15388,Q96I36,O95429,P03886,Q9BWH2,Q5JRX3,Q9Y5J9,Q6DKK2,O60220,O96000,Q96E52,Q10713,Q9P0J0,O75153,P52789,O75438,Q9UDX5,Q16891,P55786,Q9BW72,P05141,Q9BUB7,O75880,P51530,Q9GZY8,Q53H12,P17152,Q9Y512,Q9UH62,O60313,O00429,O75306,O96008,O95202,O95168,Q9NX63 85 +Lipoprotein metabolic process 0.6521321340357387 2.9650021155146216 0.0030268084811782 0.9999999957125302 0.2374193705072396 22 Q92643,Q5H8A4,Q676U5,Q8NEB9,Q9BQE5,O60762,Q9NUJ1,Q96S52,P04062,P50897 10 +Intracellular protein transmembrane transport 0.6571993372123242 2.9401621883438103 0.0032804048673795 0.9999999991489302 0.2374193705072396 21 Q9HAV7,Q9UGP8,Q3ZCQ8,Q99595,O96008,O60830,O43615,Q99442,Q15388,Q9Y5Y5,O14925,P50542,O95831,Q15629,O75381 15 +Nadh dehydrogenase complex assembly 0.6107810901536125 2.9385103103719787 0.0032979368853398 0.9999999992389548 0.2374193705072396 26 Q9P0J0,Q9H061,O75306,P03886,Q96CU9,Q86Y39,O96000,O75438,O43676,Q15070 10 +Oxidative phosphorylation 0.5007811732358989 2.9290237256766036 0.0034002846688614 0.9999999996037742 0.2374193705072396 60 Q9BSK2,Q9H3K2,P03886,O14949,P24539,O96000,O75438,O75964,O43676,P14406,Q9UDW1,Q7KZN9,P00846,P13073 14 +Cellular monovalent inorganic cation homeostasis 0.6230505217214204 2.889796776665526 0.0038549094477708 0.9999999999782008 0.2374193705072396 24 Q9HC07,Q15904,P54709,P06576,Q9Y487,P05023,Q93050,Q96PU5,Q8N511,P50897,Q92544,P55011,O75503 13 +Endoplasmic reticulum tubular network organization 0.7663911508251094 2.885161707719634 0.0039121265807713 0.9999999999848684 0.2374193705072396 12 Q6NUK4,Q9NQC3,P57088,Q8NHH9,Q9H6H4,O95197 6 +Aminoglycan metabolic process 0.6849925985622969 2.875659344071102 0.0040318458468331 0.9999999999929516 0.2374193705072396 17 O43505,Q96L58,P16278,P54802,Q9NX62,P06865,Q8NCH0,Q9NRB3,P15586,P08236,Q7LGA3 11 +Nucleotide transmembrane transport 0.859902135883132 2.8463256537830612 0.0044226940151306 0.9999999999994184 0.2374193705072396 9 Q9BSK2,P05141,P12235,P12236,Q9H2D1,Q8TDW0,Q8TB61 7 +Ph reduction 0.756275110992167 2.830647609838979 0.0046453870458629 0.9999999999998596 0.2374193705072396 12 Q9Y487,Q93050,P50897,O75503 4 +Organic acid transport 0.5146496946217543 2.797775165385204 0.0051455917068707 0.9999999999999942 0.2374193705072396 44 P31751,P23786,Q6P4A7,Q9H2D1,P53007,P28288,O43808,O43772,P08183,O60831,Q9UBX3,Q8N697,P50416,Q9H936,Q9Y619,P08195,Q15041,Q9UJS0,Q02978,O75915,Q15758,Q9NP80,Q7L0J3,P11166,Q15042,P04083,Q8TDW0,P55011 28 +Sterol metabolic process 0.5289292088274605 2.7921542594079285 0.0052358388443238 0.9999999999999968 0.2374193705072396 39 Q14849,Q16850,Q14534,Q9BQE5,Q15800,Q9H2C2,P16435,P00387,P14324,P04062,Q14739,Q15392,Q8WTV0,P05067,O15118 15 +Regulated exocytosis 0.5599321941398567 2.7893503013338243 0.005281390593391 0.9999999999999976 0.2374193705072396 33 Q15907,Q4J6C6,P11279,P49755,P09601,P0DP25,Q9BRK5,P16615,Q13277,Q7L0J3,P61026,O95721,O43760,Q9P253 14 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.5885477074944405 2.774529494105064 0.0055281621148619 0.9999999999999996 0.2374193705072396 26 O15258,P24390,O43731,Q9Y282,P49755,Q96RQ1,Q12907,Q9P2W9,Q6NUQ1,P48739,O75396,Q12981,Q9H4A6,O14579,Q9H9E3 15 +Ceramide catabolic process 0.8877163404312256 2.7501090975303035 0.0059575425973057 1.0 0.2374193705072396 7 P17900,Q05655,P04062,Q13510,P06865 5 +Regulation of cellular ph 0.6355484016718218 2.7414874238101836 0.0061161702055765 1.0 0.2374193705072396 20 Q9HC07,P50897,Q93050,Q9Y487,O75503 5 +Regulation of ph 0.6355484016718218 2.7414874238101836 0.0061161702055765 1.0 0.2374193705072396 20 Q9HC07,P50897,Q93050,Q9Y487,O75503 5 +Phospholipid metabolic process 0.4321913183996139 2.7292209203950555 0.0063484158421298 1.0 0.2374193705072396 79 Q86YN1,Q99623,Q5H8A4,Q86SQ9,Q96N66,Q8WUK0,Q9UG56,Q9UJZ1,P14324,Q10713,Q8NF37,Q9NXE4,Q08AM6,Q9BTU6,Q8NCC3,O95674,Q7L5N7,O15269,P40939,Q9NX62,Q9NUQ2,Q9NPH0,O15270,Q9NTJ5,Q8WTV0,P37268,Q92643,Q8NEB9,Q8NHP8,O60762,Q9NP80,Q96S52,Q05655,Q9HBU6 34 +Vitamin transmembrane transport 0.9068190255329288 2.7283272718657945 0.006365641799263 1.0 0.2374193705072396 6 Q8WTV0,P38435,P04062,Q9H2D1 4 +Vacuolar acidification 0.832773774197824 2.7185845762490684 0.006556189213603 1.0 0.2381207922380615 9 Q9Y487,Q93050,P50897,O75503 4 +Intracellular transport 0.3447286190204584 2.710807676723447 0.0067119544826115 1.0 0.239838218517098 537 Q86Y82,P43307,Q9NS69,Q8N4H5,Q9UGP8,Q99595,P49755,O60830,O60725,O75396,P18031,P00846,P50402,P57105,Q5JRA6,Q9HCU5,Q14849,Q53FT3,P24390,Q9Y282,P24539,P62072,P51572,P45880,Q9P2W9,O43615,Q9Y3B3,Q9BW27,O14925,O75844,Q9UBX3,Q15070,Q99797,Q15005,Q5T9L3,P61019,P50416,Q9Y584,Q8NBN3,Q9HD47,Q3ZCQ8,O43592,O75964,Q8NFH5,Q15363,P10619,Q15041,Q9UHB9,Q9Y3A6,Q96PC5,O43805,P56134,Q12907,Q9UJS0,Q8NEB9,Q12769,O43752,O95070,Q9Y371,Q96P70,Q8TCT9,Q15629,P05067,Q9BUN8,Q15907,O43464,Q99623,Q92845,Q15904,Q9NZJ7,Q9Y6B6,P23786,Q6NUQ1,Q15154,Q9UJZ1,Q8N8Q8,P40616,P28288,O00165,Q14168,Q9HAV7,Q8TEX9,P12235,P46379,Q96RL7,O14737,P27105,Q15388,P53680,O00560,O95429,O14579,Q92544,O75503,O43681,O43731,Q9BWF3,P06576,O75431,Q07666,P49458,Q99523,Q5JRX3,Q9Y2T2,Q9Y5M8,P40855,Q969Q5,Q8NHH9,Q9Y5J9,O95373,Q05655,O15118,P11279,O60220,P07602,Q96RQ1,O60784,Q14108,Q9C0E2,Q10713,Q9NR31,Q9P0J0,P52789,Q6NUK1,P61026,Q03518,O75381,Q13190,Q9Y5U9,Q00765,P16615,O15155,O95249,P56385,Q96L92,Q13277,P55786,Q7Z4Q2,Q13409,P05141,Q9H2C2,O15397,Q9UBV2,P61916,Q9GZY8,Q92973,Q53H12,Q8TBQ9,Q9UEU0,O94901,Q9Y512,Q8N1F7,P52292,O15400,O15260,P56962,Q4J6C6,Q9UH62,O60313,O14653,Q7Z3B4,Q9P253,P22626,Q08211,O96008,Q5SNT2,Q99442,Q9Y5Y5,Q9H0U4,Q86U38 170 +Protein transmembrane import into intracellular organelle 0.6933199154151269 2.706932558128794 0.0067908051283478 1.0 0.239838218517098 14 Q9HAV7,Q3ZCQ8,Q99595,O96008,O60830,O43615,P50542,Q15388,Q9Y5Y5,O14925,O75381 11 +Proton transmembrane transport 0.5043841700238247 2.702768515484236 0.0068764617616443 1.0 0.239838218517098 44 Q99623,P05141,Q9UJZ1,Q9UDW1,Q7KZN9,P00846,Q00325,P24539,P12235,Q96ES6,O00400,P13073,Q9H936,P06576,O75964,O14548,P56385,P56134,P05023,Q13423 20 +Vitamin transport 0.8710732039719682 2.6760048344888516 0.0074505570394989 1.0 0.2410507081146841 7 Q8WTV0,P38435,P04062,Q9H2D1 4 +Protein localization to endoplasmic reticulum 0.5301782009994078 2.66492145554823 0.0077006306202573 1.0 0.2410507081146841 36 O15258,Q9Y5M8,O43681,Q9NQC3,P24390,Q9UGP8,O43731,Q9UHB9,Q96HY6,P46379,P51572,P61026,Q99442,Q15042,Q5JRA6,Q15629,Q15005 17 +Inorganic anion transport 0.5997581870167024 2.662621187071985 0.0077534644811023 1.0 0.2410507081146841 23 O43681,Q9C0H2,P45880,Q9UHG3,Q8TDW0,Q9Y277,Q96S66,Q86WC4,P51790,O43826,P21796,Q00325,P54105,Q9UBX3,P55011 15 +Purine containing compound transmembrane transport 0.8567481867275002 2.6481805426344516 0.0080926293700782 1.0 0.2410507081146841 8 P05141,P12235,P12236,Q8TDW0,Q8TB61,Q99808 6 +Cation transport 0.457934226472138 2.644562290245101 0.00817966499425 1.0 0.2410507081146841 144 Q15907,Q99623,P98194,Q9HC21,Q9H4I9,P20020,P05141,P55011,Q9UJZ1,Q9UDW1,P00846,Q7KZN9,Q00325,P62942,O43808,Q9BPX6,Q9H0U3,P24539,P12235,Q96ES6,Q9HD20,O00400,Q96PU5,P27105,Q96HE7,P13073,O75844,Q9UM00,Q70HW3,Q99808,Q9P246,Q9H936,O76024,Q9HD47,P0DP25,P54709,P06576,O75964,Q96GC9,P16615,Q9Y619,O14548,O00429,P21796,P56385,Q9HC07,P56134,Q8IYU8,P78417,O95202,O75027,P05023,O15173,Q8N4V1,Q13423,P05067 56 +Steroid metabolic process 0.4617856751681375 2.638108061697375 0.0083370010576553 1.0 0.2410507081146841 65 Q16850,O14734,Q9BQE5,Q9H2C2,Q99538,P14324,Q15392,P61916,Q14849,O95470,P16435,P04062,Q13510,Q8NBQ5,Q14534,Q53GQ0,P35610,P00387,O94905,Q8WTV0,P37268,P38435,Q15800,Q06520,P05023,Q14739,Q96SU4,P05067,O15118 29 +Glycerolipid biosynthetic process 0.4906379091952714 2.6330694924917166 0.0084617032295362 1.0 0.2410507081146841 49 Q5H8A4,Q8WUK0,Q96N66,Q9UG56,Q10713,Q8NF37,Q08AM6,Q9BTU6,Q8NCC3,O14735,Q7L5N7,O95674,Q96PE3,Q9NX62,Q9NUQ2,Q9NPH0,Q99943,Q9NTJ5,O43292,Q8WTV0,Q92643,Q86UL3,Q8NEB9,O60762,Q96S52,Q9HBU6,Q92604 27 +Negative regulation of calcium ion transmembrane transport 0.8605305633631241 2.6287065401034657 0.008571028954361 1.0 0.2410507081146841 7 P0DP25,P78417,P21796 3 +Secondary alcohol metabolic process 0.4973221161024475 2.626628806913937 0.0086235347614098 1.0 0.2414589733194763 43 Q14849,Q16850,Q14534,Q9BQE5,Q15800,Q9H2C2,P16435,P00387,P14324,P04062,Q14739,Q15392,Q8WTV0,P05067,O15118 15 +Establishment of protein localization 0.3723256471669383 2.621532660388522 0.0087535374482108 1.0 0.24323469234537 505 Q86Y82,P98194,P43307,Q9NS69,Q8N4H5,Q9UGP8,Q99595,P49755,O60830,O60725,O75396,P18031,P50402,P57105,Q5JRA6,P50897,Q9HCU5,Q9NPA0,P41208,Q53FT3,P24390,Q9Y282,P62072,P51572,Q9P2W9,O43615,Q9Y3B3,Q9BW27,O14925,Q15070,Q99797,Q15005,Q5T9L3,Q676U5,A6NIH7,P61019,Q9Y584,P50416,Q9HD47,Q3ZCQ8,P0DP25,O43592,O15127,Q8NFH5,Q96GC9,Q15363,P10619,O95721,Q15041,Q9UHB9,Q9H4A6,Q9Y3A6,Q9H9E3,Q96PC5,Q12907,Q8NEB9,Q12769,O43752,O95070,Q9Y371,Q96P70,Q15042,Q8TCT9,Q15629,P55011,Q9BUN8,Q15907,O43464,Q99623,Q15904,Q9Y6B6,Q6NUQ1,Q15154,Q8N8Q8,P40616,O00165,Q14168,Q96A33,Q9HAV7,Q9H8Y8,Q8WUM4,Q8TEX9,P46379,Q9HD20,Q96RL7,O14737,P27105,P40939,Q15388,O60831,O00560,P53680,O14579,O95429,O43731,Q8N5M9,Q5JRX3,Q9Y2T2,Q9Y5M8,P40855,Q969Q5,Q9Y5J9,Q9BTX1,O95373,Q05655,Q8N4V1,Q16836,O15118,Q16850,P11279,O60220,Q99832,O60784,Q14108,Q9C0E2,Q10713,Q9NR31,Q9P0J0,P52789,P61026,Q03518,O75381,Q13190,Q9Y5U9,Q8NFH4,O15155,O95249,Q96L92,Q96KC8,Q13277,P04083,P55786,Q9H1Z9,Q7Z4Q2,P27824,O15397,Q9UBV2,Q9GZY8,Q92973,Q53H12,Q8TBQ9,Q9UEU0,Q15006,Q9Y512,Q8N1F7,P52292,O15400,O15260,P56962,Q4J6C6,Q07820,O14653,Q7Z3B4,O00429,Q9P253,O96008,P49321,Q99442,Q9Y5Y5,Q9H0U4 160 +Vacuole organization 0.4795851036504872 2.6160001672590045 0.0088966514006698 1.0 0.2458570274028594 55 Q86Y82,Q14108,O75396,P10253,P50897,O14773,P11117,Q9UHD9,P04062,O75503,Q676U5,P56962,Q96GC9,P16615,Q8N511,Q9P253,Q9HC07,Q8NEB9,Q9Y371,Q9H0U4,P54802 21 +Regulation of oxidoreductase activity 0.6656533075867274 2.608463600501946 0.0090949683971084 1.0 0.2487052256921638 15 P0DP25,P16435,P00374,Q8TCT9,Q8WTV0,Q15070 6 +Regulation of lysosomal lumen ph 0.8792955558797708 2.6083863147049273 0.0090970223752495 1.0 0.2487052256921638 6 Q9HC07,P50897,O75503 3 +Oligosaccharide lipid intermediate biosynthetic process 0.8780441233053589 2.602890656201211 0.0092441431241847 1.0 0.2487052256921638 6 Q86YN1,Q9BV10,Q86SQ9 3 +Monovalent inorganic cation homeostasis 0.5646812269891544 2.594908318834731 0.0094616153623645 1.0 0.2487052256921638 26 Q9HC07,Q15904,P54709,P06576,Q9Y487,P05023,Q93050,Q96PU5,Q8N511,P50897,Q92544,P55011,O75503 13 +Glycosphingolipid metabolic process 0.8444518843834882 2.592205166136297 0.0095362881800489 1.0 0.2487052256921638 8 P06280,P16278,P17900,Q05655,P04062,P06865 6 +Peptide catabolic process 0.7640720794353179 2.576623502413297 0.0099770556562917 1.0 0.2487052256921638 10 P09960,P42892,Q9UIQ6,Q9UJ14,Q9NZ08,O14773 6 +Atp transport 0.8651944627554342 2.546247064015347 0.010888809101609 1.0 0.250225354604809 6 P05141,P12235,P12236,Q6NUK1,Q08722 5 +Glycerolipid metabolic process 0.4483306207597047 2.5404373650380756 0.011071392229643 1.0 0.250225354604809 67 Q99623,Q5H8A4,Q96N66,Q8WUK0,Q9UG56,Q9UJZ1,Q10713,Q9UBV2,Q8NF37,Q08AM6,Q9NXE4,Q9BTU6,Q8NCC3,Q53H12,O14735,Q7L5N7,O95674,P40939,P50416,Q96PE3,Q9NX62,Q9NUQ2,Q9NPH0,Q99943,Q9NTJ5,O43292,Q8WTV0,Q92643,Q86UL3,Q8NEB9,Q8NCG7,O60762,Q9NP80,Q96S52,Q9HBU6,Q92604 36 +Respiratory chain complex iv assembly 0.7943672194536686 2.5341543214638116 0.0112719078762031 1.0 0.250225354604809 9 Q9Y2R0,Q8N8Q8,Q7KZN9,Q96I36,Q15070 5 +Organelle fusion 0.4835702157436989 2.528019436003142 0.0114708001656143 1.0 0.250225354604809 46 Q86Y82,O75396,Q9UJZ1,Q96E52,Q9Y6C9,Q9GZY8,Q9UEU0,O15400,Q13190,P56962,O60313,O14653,Q12981,O15155,O95721,O95249,Q9P253,Q9NX63,O43752,Q13277,P04083 21 +Sulfur compound transport 0.8282915593680183 2.518038872716992 0.011801029600341 1.0 0.2514993133650199 8 Q9HC21,O00400,Q8TB61,Q9UBX3,Q70HW3 5 +Lipid localization 0.4309408132648018 2.5097135034417835 0.012082914811905 1.0 0.2529535013413175 73 Q86Y82,P07602,Q99720,Q9NZJ7,Q9BQE5,P23786,Q9Y6B6,Q9H2C2,Q14108,Q9H6V9,Q9UJZ1,P61916,O43808,Q14849,P17900,O95674,Q9BUR5,P04062,O15260,Q14534,P50416,P35610,Q96GC9,Q8WTV0,Q9NP80,Q05655,Q96SU4,P04083,Q9H2V7,O15118 30 +Metal ion transport 0.4157649713723597 2.5092591679076452 0.0120984682831593 1.0 0.2529535013413175 91 Q15907,Q9H4I9,P62942,Q9H0U3,Q9HD20,P27105,Q96HE7,O75844,Q9P246,O76024,Q9HD47,P0DP25,Q96GC9,P16615,O00429,P21796,Q9HC07,Q8IYU8,P78417,O95202,O75027,P05023,O15173,Q8N4V1 24 +Dicarboxylic acid transport 0.6372698699550202 2.501958010284152 0.0123508572363875 1.0 0.2573837658835378 16 Q9H936,Q9UJS0,Q02978,Q9H2D1,Q15042,O60831,Q15041,Q8TDW0,Q9UBX3,P55011 10 +Amino acid transport 0.6117994017668807 2.486443048114914 0.0129027219931709 1.0 0.2595644127701511 18 Q8N697,Q9H936,Q9UJS0,Q6P4A7,O75915,Q9Y619,P08195,Q7L0J3,Q15042,O60831,Q15041,Q8TDW0,P55011 13 +Negative regulation of calcium ion transport 0.8192185984125123 2.4760972324722115 0.0132827398798365 1.0 0.263828420863253 8 P0DP25,P78417,P21796 3 +Transition metal ion transport 0.6308816030391244 2.461523909219764 0.0138348176244507 1.0 0.2661651560522556 16 Q15907,Q9HC07,O75027,Q9HD20,O15173,Q8N4V1 6 +Amino acid transmembrane transport 0.6615529486158309 2.456923218120916 0.0140132633758252 1.0 0.2682780181227259 13 Q8N697,Q9H936,Q9UJS0,O75915,Q9Y619,P08195,O60831,Q15041,Q8TDW0 9 +Vesicle docking 0.6066272796863894 2.4520098768741985 0.0142060762534348 1.0 0.2702045318634116 18 Q86Y82,P56962,O15400,O43752,Q13277,Q9UEU0,P61026,Q9P253,Q13190 9 +Positive regulation of peptidase activity 0.5054408509227988 2.451115411026653 0.0142414282841791 1.0 0.2702045318634116 36 O43464,Q9P0J0,Q96HY6,Q9BXK5,Q9NZJ7,P51572,O75915,Q99538,Q96A26,P49327,O14737,P61289,Q9NR28,O95831,Q92542,P05067 16 +Glycerophospholipid biosynthetic process 0.4760425568820122 2.444966191366489 0.0144865721142724 1.0 0.2716125438298389 45 Q5H8A4,Q8WUK0,Q96N66,Q9UG56,Q10713,Q8NF37,Q6P1A2,Q08AM6,Q9BTU6,O14735,Q7L5N7,O95674,O95573,P48651,Q9H490,Q96PE3,Q9NX62,Q9NUQ2,Q9NPH0,Q99943,Q9NTJ5,O43292,Q92643,Q6IAN0,Q86UL3,Q8NEB9,O60762,Q96S52,Q9HBU6 29 +Cristae formation 0.7382051364466494 2.4430835499695336 0.0145623655482345 1.0 0.2722305747781727 10 Q16891,O95202,Q96E52,Q9BUR5,Q9Y512,Q5XKP0 6 +Protein targeting to membrane 0.5149775547756051 2.4179564386621073 0.0156079451908719 1.0 0.2850549066889005 33 O43681,P43307,Q9UGP8,Q9GZY8,P40855,P46379,O60725,Q15041,Q9H9H4,P49458,P27105,Q99442,Q9Y5Y5,P50542,O00560,Q9UHB9,Q15629 17 +Membrane organization 0.4656325712813212 2.4099091396666994 0.015956493800328 1.0 0.2873072934699293 223 Q86Y82,O15258,P98194,Q6NUK4,Q9NS69,Q96CP7,O60220,P49755,P05141,Q9NZJ7,Q9H2C2,O75396,Q96E52,Q8N8Q8,P50402,Q15392,Q5JRA6,P50897,Q9HCU5,Q9NR31,P61916,Q14849,Q9P0J0,Q96A33,Q9H3K2,P52789,Q53H12,P62072,P12235,P45880,Q9P2W9,P57088,P17152,Q9UEU0,Q9BUR5,O14737,Q15006,O94901,Q9Y512,Q8N1F7,O75844,Q15070,Q13190,O15400,P56962,Q9NQC3,Q9Y584,Q8IXJ6,O14657,P0DP25,Q00765,O60313,O14653,Q96GC9,P16615,Q12981,O15155,O00429,O95249,O43760,Q86XL3,Q8N4V1,P04083,Q13505,Q9NX63,Q8NHH9,Q16891,O43752,Q9Y5J9,O95202,Q13277,Q05655,Q9H6H4,Q5XKP0,Q15629,O15118 76 +Calcium ion transmembrane transport 0.5002752094709296 2.405809277861255 0.0161366866328207 1.0 0.2886821720010903 36 Q9BPX6,Q9HC07,P98194,Q8IYU8,Q9H4I9,P20020,P0DP25,P78417,O95202,Q96GC9,P16615,Q9UJZ1,P21796,Q96HE7,Q9P246,P62942 16 +Steroid biosynthetic process 0.4745964487064703 2.4035370620969307 0.0162373210070043 1.0 0.2890879896933326 42 Q14849,Q16850,Q14534,O14734,Q53GQ0,Q15800,Q9H2C2,P16435,P00387,P05023,P14324,Q14739,O94905,Q15392,Q13510,Q96SU4,Q8NBQ5,P37268 18 +Phospholipid biosynthetic process 0.4490620911319836 2.3907035057163477 0.0168161267989839 1.0 0.2906892810442313 60 Q86YN1,Q5H8A4,Q86SQ9,Q8WUK0,Q96N66,Q9UG56,P14324,Q10713,Q8NF37,Q08AM6,Q9BTU6,O14735,Q7L5N7,O95674,O15269,Q96PE3,Q9NX62,Q9NUQ2,Q9NPH0,Q99943,O15270,Q9NTJ5,O43292,Q92643,Q86UL3,Q8NEB9,O60762,Q96S52,Q9HBU6,Q92604 30 +Lipoprotein biosynthetic process 0.6080881432841205 2.386016273789324 0.0170319973553549 1.0 0.2910090730931083 17 Q92643,Q5H8A4,Q676U5,Q8NEB9,O60762,Q96S52,P04062 7 +Reactive nitrogen species metabolic process 0.6483337740540476 2.3780977757882695 0.0174022108474685 1.0 0.2918428816530603 13 O43169,Q08722,P00387,P16435 4 +Protein import into mitochondrial matrix 0.7600753067947239 2.3658270659525966 0.0179898453703961 1.0 0.2973526669713725 9 Q9HAV7,Q3ZCQ8,Q99595,O96008,O60830,O43615,O14925 7 +Respiratory chain complex iii assembly 0.877376131659571 2.365769524185282 0.017992641451787 1.0 0.2973526669713725 5 Q9BSK2,Q69YU5 2 +Hormone metabolic process 0.52448431745553 2.3656202565347892 0.0179998964707566 1.0 0.2973526669713725 29 Q14849,Q53GQ0,Q9Y394,Q6NUM9,O95470,Q9HB40,P16435,Q8NBQ5,P42892,P05023,Q9HBH5,Q8NBN7,Q96HE7,O75844 14 +Glycolipid catabolic process 0.8019626754777665 2.3608008034913923 0.0182355227068047 1.0 0.2973526669713725 7 P17900,Q05655,P04062,P06865 4 +Endomembrane system organization 0.4484230812678285 2.3606006795400183 0.0182453650281364 1.0 0.2973526669713725 173 O75122,Q6NUK4,Q96CP7,P49755,Q9BTV4,Q9H2C2,Q14108,O75396,P50402,Q5JRA6,P40616,Q9NPA0,O95197,Q9NXE4,Q53FT3,Q9BTU6,Q9H8Y8,Q96A33,Q8WUM4,P57088,Q9P2W9,Q9UEU0,P61026,Q9Y3B3,Q15006,O94901,Q8N1F7,O75844,Q5T2E6,P48729,Q13190,P61019,O15260,Q9NQC3,P56962,Q8N5M9,Q8IXJ6,O14657,Q00765,Q15363,Q96GC9,Q12981,P16615,O15155,O95721,O00429,O43760,Q15041,Q9H4A6,Q9Y3A6,Q8N4V1,Q7Z3D4,Q9H9E3,Q86XL3,Q9P253,Q12907,Q8NEB9,Q8NHH9,Q8TBA6,O43752,Q13277,Q05655,Q9Y371,Q9H6H4,Q15042,Q15629 66 +Protein n linked glycosylation 0.5794228400967034 2.3586914365977827 0.0183394978382465 1.0 0.2974764982930408 20 Q86YN1,Q9HC07,P04844,Q86SQ9,Q9BV10,Q9BT22,P46977 7 +Membrane docking 0.5098622347824493 2.3400835728062916 0.0192794251853061 1.0 0.307124756938363 32 Q86Y82,P56962,Q13190,O43752,Q96GC9,P16615,Q9UEU0,Q13277,P61026,O95721,Q9Y5Y5,Q9P253,O15400 13 +Negative regulation of cation channel activity 0.8707174749338362 2.3373283636664035 0.0194221168183659 1.0 0.3078478167020793 5 P0DP25,P78417 2 +Ceramide biosynthetic process 0.7165201795961261 2.3294115890179556 0.0198372717133559 1.0 0.3105623192469612 10 Q96G23,Q53H12,O15269,Q05655,P04062,Q13510 6 +Endoplasmic reticulum membrane organization 0.7522930853503538 2.3271370091733816 0.0199579743080684 1.0 0.3105623192469612 9 Q9NQC3,Q00765,Q8NHH9,Q9P2W9,Q15363,Q12981 6 +Amyloid fibril formation 0.7944748293755912 2.325910226521521 0.0200233403667302 1.0 0.3105623192469612 7 P05067 1 +Calcium ion import 0.6655562269963158 2.324545734944495 0.0200962633291945 1.0 0.3105623192469612 12 P16615,O75844,P21796,Q9H4I9 4 +Mitochondrial cytochrome c oxidase assembly 0.7851801857886691 2.3167852581381507 0.020515432477675 1.0 0.3105623192469612 8 Q9Y2R0,Q8N8Q8,Q15070,Q96I36 4 +Alcohol metabolic process 0.3943403016944389 2.308479432713334 0.0209724854830166 1.0 0.3105623192469612 83 Q16850,Q86SQ9,Q9Y394,Q9BQE5,Q9H2C2,P14324,Q10713,Q15392,Q8NBN7,P61916,Q14849,P16435,O15269,P04062,Q13510,P51648,Q14534,Q9NX62,P00387,P00374,Q8WTV0,P37268,Q15800,Q14739,Q9HBH5,P05067,O15118 27 +Calcium ion transport 0.4538985721086477 2.2953963370663835 0.0217104210852661 1.0 0.3105623192469612 51 Q9HC07,Q8IYU8,O76024,Q9H4I9,O75844,P0DP25,P78417,O95202,Q96GC9,P16615,O00429,P21796,Q96HE7,Q9P246,P62942 15 +Glycerophospholipid metabolic process 0.4382720730988871 2.293703031022611 0.0218075625355373 1.0 0.3105623192469612 61 Q99623,Q5H8A4,Q96N66,Q8WUK0,Q9UG56,Q9UJZ1,Q10713,Q8NF37,Q9NXE4,Q08AM6,Q9BTU6,Q8NCC3,O14735,Q7L5N7,O95674,P40939,Q96PE3,Q9NX62,Q9NUQ2,Q9NPH0,Q99943,Q9NTJ5,O43292,Q8WTV0,Q92643,Q86UL3,Q8NEB9,O60762,Q9NP80,Q96S52,Q9HBU6,Q92604 32 +Glycoside catabolic process 0.8088332234673654 2.2931217969309525 0.0218409938173995 1.0 0.3105623192469612 6 P06280,Q9NUJ1,P04062,Q9BTY2,P08236 5 +Midbrain development 0.562713457660736 2.2894048840107497 0.0220558386349449 1.0 0.3124727235791146 21 Q5T9L3,P24539,O14949 3 +Aerobic respiration 0.3938038259743296 2.2821892827064754 0.0224781675660721 1.0 0.313371289010928 85 Q9BSK2,Q9H3K2,P03886,O14949,P24539,O96000,O75964,O75438,O43676,P14406,Q9UDW1,P00846,Q7KZN9,P13073,Q13423,Q15070 16 +Regulation of regulated secretory pathway 0.5810449423840555 2.279602704483937 0.0226312624190911 1.0 0.3133862830844087 18 Q4J6C6,P11279,P0DP25,P09601,P16615 5 +Protein exit from endoplasmic reticulum 0.5538972856598144 2.2764941490552215 0.0228164503999079 1.0 0.3137616628826061 22 Q9BUN8,O15260,Q92544,Q9HD47,O15027,Q9Y6B6,P51572,Q8TCT9,P60604,Q9UBV2,Q9HCU5,Q9NR31 12 +Exocytosis 0.4112655274192532 2.2750122703091593 0.022905193766131 1.0 0.3137616628826061 73 Q15907,O75122,P11279,P49755,P09601,Q5JRA6,Q8TBQ9,Q9UEU0,P61026,O00560,P56962,Q4J6C6,Q8N5M9,P0DP25,P16615,O95721,O43760,Q9P253,Q9BRK5,Q13277,Q7L0J3,P04083,Q15042 23 +Amyloid precursor protein catabolic process 0.6216146935043395 2.2739098671620277 0.022971406317132 1.0 0.3139919538746045 14 Q9NQC3,Q16799,P62942,Q15392,O95197 5 +Atp synthesis coupled electron transport 0.4887723545437681 2.2654908746767215 0.0234825733769101 1.0 0.3189214452641903 35 Q9H3K2,P03886,O14949,O96000,O43676,Q9UDW1,Q7KZN9,P13073 8 +Proteoglycan metabolic process 0.7393064857417092 2.2621651792760864 0.0236871997927181 1.0 0.3208421098033794 9 Q96L58,Q99805,Q9NX62,Q8NCH0,Q9NRB3,Q7LGA3 6 +Cytosolic calcium ion transport 0.5588290349965653 2.261554344654616 0.0237249514801114 1.0 0.3208421098033794 21 Q8IYU8,Q9H4I9,P0DP25,P78417,P16615,P21796,Q96HE7,P62942 8 +Protein insertion into mitochondrial inner membrane 0.7709529036972901 2.249268702340021 0.0244954057851909 1.0 0.3219419603426431 8 Q9P0J0,Q9Y584,O60220,P62072,Q9Y5J9 5 +Neutral lipid metabolic process 0.6247589818759094 2.2356377813228465 0.0253755076528925 1.0 0.3274102521153002 13 P50416,Q86UL3,Q8NCC3,Q8NCG7,Q96N66,Q9NUQ2,Q9UBV2,Q8WTV0 8 +Mitochondrial electron transport ubiquinol to cytochrome c 0.9811753723607132 2.2201980271613797 0.0264053281829641 1.0 0.3349945427762876 4 Q9UDW1 1 +Cellular homeostasis 0.4177645265259533 2.210017543412903 0.027103944770642 1.0 0.3371046234563163 131 Q15907,P98194,Q9H4I9,Q15904,P09601,P20020,Q9UJZ1,P10253,O75880,P50897,P62942,Q9BPX6,Q96A33,P52789,Q96RR1,P51572,Q9HD20,Q96PU5,Q96HE7,Q9P246,Q9UM00,Q92544,Q99808,O75503,P54105,Q9NQC3,Q8N5M9,O76024,Q07820,P0DP25,P54709,P06576,P16615,Q93050,Q9BWH2,Q8N511,Q9Y487,Q96TC7,Q9HC07,Q8IYU8,P78417,Q16891,O95202,O75027,P05023,Q7L0J3,Q9Y639,P05067,P55011 49 +L alpha amino acid transmembrane transport 0.6689336046442694 2.2024143095241513 0.0276360560041841 1.0 0.3410772271118342 11 Q8N697,Q9H936,Q9UJS0,O75915,Q9Y619,P08195,O60831,Q15041 8 +Protein insertion into er membrane 0.643461694516458 2.196402467740191 0.0280631491929141 1.0 0.3430180312887742 12 Q96A33,O43681,P46379,Q5J8M3,Q15006,Q15629,Q8N4V1,Q9NPA0 8 +Neuron recognition 0.7871448232035144 2.1936649398881545 0.0282595060901151 1.0 0.3443573328152279 6 P35613,Q9NQC3,P05067 3 +Peroxisome organization 0.6429420808014406 2.1933652020956584 0.0282810773646238 1.0 0.3443573328152279 12 P40855,Q9GZY8,O14734,O75192,O00429,P50542,Q9Y5Y5,P28288,O75381 9 +Amyloid precursor protein metabolic process 0.5786790648253048 2.190926394968984 0.0284571193122937 1.0 0.3451783403605711 17 Q9NQC3,P49755,P35610,Q16799,O95197,Q15392,P62942,Q92542 8 +Regulation of tor signaling 0.6104447944342423 2.1479490109657977 0.0317178062919647 1.0 0.3599971014137998 13 O75844,P04062,Q15382,Q9P2J5 4 +Lipid biosynthetic process 0.4188076437695042 2.1405809045925595 0.0323078500476312 1.0 0.3645990116539667 143 Q86YN1,Q5H8A4,Q16850,Q96G23,Q86SQ9,Q96N66,Q8WUK0,Q9H2C2,Q8NBX0,Q9UG56,P14324,Q10713,Q15392,Q06136,Q8NF37,Q9NZ01,Q14849,Q9NXE4,Q9BTU6,Q08AM6,Q99805,O95470,Q8NCC3,Q53H12,O95674,P16435,O15269,P04062,Q13510,Q8NBQ5,Q14534,Q96PU8,Q5T2R2,Q53GQ0,P35610,Q9NX62,Q9NUQ2,Q9UKU0,P00387,Q9NPH0,O94905,O95864,Q9NTJ5,Q8WTV0,P37268,Q9P035,Q92643,Q8NEB9,Q8NCG7,Q15800,O60762,Q9NP80,P05023,Q05655,Q14739,Q96SU4,P04083,Q9HBU6,Q8IVS2 59 +Sarcoplasmic reticulum calcium ion transport 0.7753271141629996 2.1389905569071876 0.0324364331593525 1.0 0.364895520638663 6 P0DP25,P78417,O75844 3 +Positive regulation of mitochondrial translation 0.7544941209215432 2.1371282868514156 0.0325875588078887 1.0 0.3654398745348608 7 Q9Y2R0,Q567V2 2 +Regulation of anion transport 0.6565142087932596 2.132722755693815 0.0329474760585086 1.0 0.3656909959888312 11 Q15907,O75915,Q7L0J3,Q15041,Q15042,P55011 6 +Organelle membrane fusion 0.487844407965429 2.1218731835840257 0.0338483889145209 1.0 0.3728602425315336 31 Q86Y82,P56962,Q13190,O14653,O43752,Q13277,O75396,Q9UEU0,Q12981,O15155,O95249,P04083,O15400 13 +Organic cation transport 0.8197176978490952 2.116429418777383 0.0343083022173362 1.0 0.3772726105421961 5 Q9HC21,Q70HW3,Q99808 3 +Isoprenoid metabolic process 0.5108654717175063 2.1155313029848686 0.0343846898895956 1.0 0.3774595663873401 25 Q5T2R2,Q86SQ9,Q9Y394,Q9HB40,Q6NUM9,O60762,P14324,Q9HBH5,Q8NBN7,P51648,P61916,P37268 12 +Macromolecule depalmitoylation 0.8188924333931208 2.1128105558982924 0.034616985825328 1.0 0.3781518639465599 5 P50897,Q9UMR5 2 +Endoplasmic reticulum unfolded protein response 0.5446620050069343 2.112702484340191 0.0346262405312929 1.0 0.3781518639465599 20 Q9BUN8,Q96HY6,O76024,Q7Z2K6,P57088,Q9Y4P3,P18031,Q96HE7 8 +Protein processing 0.4410417768166667 2.110293169514613 0.0348331115763904 1.0 0.3797585886441471 46 O43464,Q99538,Q9UG56,Q96E52,Q10713,Q15392,P67812,Q96HE7,O75844,Q99797,Q15005,O75503,P42892,Q5JRX3,Q92896,Q92542,Q8NEB9,Q9BXS4,Q8TCT9 19 +L amino acid transport 0.6509919244336317 2.101550356880236 0.0355926824085377 1.0 0.3859508890453444 11 Q9H936,Q9UJS0,O75915,P08195,Q9Y619,O60831,Q15041 7 +Phosphatidylethanolamine metabolic process 0.8148748891397828 2.0951732523062616 0.0361555940802149 1.0 0.3905205502734927 5 Q9UG56,Q8NCC3,Q9NP80 3 +Antigen processing and presentation 0.5421697573586841 2.0947986741998457 0.036188893031952 1.0 0.3905205502734927 20 P10321,Q9Y6B6,Q99538,P04439,Q9UIQ6,P61026,P04062,Q9NZ08,Q03518,Q9BYJ9 10 +Chemokine production 0.7437442659560696 2.0856534383112018 0.0370100269889708 1.0 0.3966875742696434 7 P09601 1 +Positive regulation of chemokine production 0.7437442659560696 2.0856534383112018 0.0370100269889708 1.0 0.3966875742696434 7 P09601 1 +Carbohydrate derivative catabolic process 0.4635983607253443 2.0774197963100143 0.0377628306414514 1.0 0.3987052351446272 36 P06280,P16278,P35610,Q9H773,P17900,Q9NUJ1,Q13126,Q05655,P04062,P06865,Q9BTY2,P15586,P08236,P54802 14 +Cellular hormone metabolic process 0.5511196432905424 2.0734481480609075 0.0381305919826102 1.0 0.4012550374858789 18 Q14849,Q53GQ0,Q9Y394,Q6NUM9,O95470,Q9HB40,P42892,Q9HBH5,Q8NBN7 9 +Positive regulation of sequestering of calcium ion 0.9432982335056734 2.069764935389529 0.0384743625002543 1.0 0.4019787841549396 4 P0DP25,P78417 2 +Negative regulation of ryanodine sensitive calcium release channel activity 0.9432982335056734 2.069764935389529 0.0384743625002543 1.0 0.4019787841549396 4 P0DP25,P78417 2 +Negative regulation of calcium ion transport into cytosol 0.9432982335056734 2.069764935389529 0.0384743625002543 1.0 0.4019787841549396 4 P0DP25,P78417 2 +Glycosaminoglycan catabolic process 0.8085667215815444 2.0674132058311 0.0386952349424425 1.0 0.4019787841549396 5 P15586,P54802,P16278,P08236 4 +Aminoglycan catabolic process 0.8085667215815444 2.0674132058311 0.0386952349424425 1.0 0.4019787841549396 5 P15586,P54802,P16278,P08236 4 +Antigen processing and presentation of exogenous peptide antigen 0.7597989573587142 2.066634956788362 0.0387685642993986 1.0 0.4019787841549396 6 Q03518,Q9UIQ6,Q99538 3 +Mitochondrial calcium ion transmembrane transport 0.7003638652980728 2.064258427278575 0.0389932204267955 1.0 0.4020704420223898 9 Q9BPX6,Q8IYU8,Q9H4I9,O95202,Q9UJZ1,P21796 6 +Regulation of mitochondrial gene expression 0.6442605626148596 2.063399627366835 0.0390746753341995 1.0 0.4020704420223898 11 Q9Y2R0,Q567V2 2 +Proteoglycan biosynthetic process 0.7305689339575545 2.054616553484396 0.0399160555248785 1.0 0.4020704420223898 8 Q96L58,Q99805,Q8NCH0,Q9NRB3,Q7LGA3 5 +Mucopolysaccharide metabolic process 0.6647349954276685 2.0514765987797414 0.0402205562595121 1.0 0.4034894195362284 10 O43505,Q96L58,P16278,Q9NX62,Q8NCH0,P15586 6 +Regulation of ryanodine sensitive calcium release channel activity 0.8049044094363651 2.0512593709612807 0.0402416948437298 1.0 0.4034894195362284 5 P0DP25,P78417 2 +Sterol biosynthetic process 0.508778336858197 2.0429186996057345 0.0410604868792634 1.0 0.4034894195362284 24 Q16850,Q14534,Q15800,Q9H2C2,P16435,P00387,P14324,Q14739,Q15392 9 +Alcohol biosynthetic process 0.4591198543711988 2.0365073007293795 0.04169944074769 1.0 0.4061284502991991 36 Q16850,Q86SQ9,Q15800,Q9H2C2,P16435,P00387,P14324,O15269,P04062,Q15392,Q13510,P00374,Q14739 13 +Regulation of exocytosis 0.4547771659941789 2.034326435586695 0.0419186935227233 1.0 0.4061512439488258 37 O75122,O43633,Q4J6C6,P11279,Q8WUM4,P09601,P0DP25,P16615,P61026,Q06787,O00560,Q15042,Q9P253,P04083 14 +Cellular transition metal ion homeostasis 0.5333586726632966 2.0312144644642216 0.0422332437176835 1.0 0.4077378133328862 20 P09601,Q8N511,O75880,Q9Y487,P05067 5 +Transition metal ion homeostasis 0.506866058253079 2.0280280619573774 0.0425573840510054 1.0 0.4092204735676101 24 P09601,Q9Y487,P30519,P05067 4 +Signal peptide processing 0.797401477330893 2.0180801551006406 0.043582914099749 1.0 0.4146901227814442 5 Q8TCT9,P67812 2 +Inorganic anion transmembrane transport 0.7229551451187202 2.017419267968467 0.0436517781879695 1.0 0.4147245174330854 8 Q02978,Q9UHG3,P51790,O43826,Q00325,Q9UBX3,P55011 7 +Mitochondrial calcium ion homeostasis 0.6566937360388111 2.007493297150779 0.0446971636291131 1.0 0.4184023152086054 10 Q9BPX6,Q8IYU8,Q9H4I9,Q16891,O95202,P51572 6 +Regulation of er to golgi vesicle mediated transport 0.745880026367818 2.001283867052339 0.0453618073242634 1.0 0.4218323661047088 6 Q9Y6B6,Q9P2W9,Q6NUQ1,Q9HCU5,Q9NR31 5 +Protein maturation 0.3992755855434634 2.0003563774966597 0.0454617952771752 1.0 0.4218323661047088 68 O43464,Q9NRN7,Q99538,Q9UG56,Q9UJZ1,Q96E52,Q10713,Q15392,P62942,Q9BU89,P67812,Q96HE7,O75844,Q99797,Q15005,O75503,O76024,P42892,Q10471,Q5JRX3,Q92896,Q92542,Q8NEB9,Q9BXS4,Q8TCT9,Q9BU23 26 +Sensory perception of light stimulus 0.5752985678783676 1.981873527422984 0.0474933974825977 1.0 0.4361992094857713 14 O43924,O76024,Q9H6K4,O60313,P53611,Q15555,P50897,Q99797 8 +Peroxisome fission 0.788797364085663 1.9798915973222837 0.0477157107963641 1.0 0.4361992094857713 5 O75192,O00429,P40855,Q9GZY8 4 +Cellular respiration 0.3809614405844299 1.972109331836162 0.0485971269040392 1.0 0.4361992094857713 100 Q9BSK2,Q9H3K2,P03886,O14949,P24539,O96000,O75964,Q9NZ45,O43676,P14406,Q9UDW1,P04062,P00846,Q7KZN9,P13073,Q13423,Q15070 17 +Lipoprotein localization 0.7868204283360696 1.971096211569356 0.0487128719909932 1.0 0.4361992094857713 5 O15260,Q5JRA6,A6NIH7,Q96GC9 4 +Chloride transport 0.626939230147561 1.964456079748532 0.0494772248492942 1.0 0.4361992094857713 11 Q9C0H2,Q9UHG3,Q96S66,Q86WC4,P08183,P51790,P54105,P55011 8 +Protein import 0.368575354079156 1.957740092896892 0.0502605181440902 1.0 0.4388129853349419 84 Q99623,Q9NS69,Q99595,O60830,O15397,Q53FT3,Q9HAV7,Q8TEX9,Q92973,O43615,O14737,Q9BW27,O14925,Q9Y512,Q8N1F7,P52292,O75381,Q9HD47,Q3ZCQ8,Q7Z3B4,Q8NFH5,P40855,O96008,O95373,Q05655,Q9Y5Y5,Q96P70,Q7Z4Q2 28 +Prostate gland development 0.7835117986588231 1.956358721835443 0.0504229111709342 1.0 0.4393757606766336 5 P07602,Q9NZJ7 2 +Selective autophagy 0.4772838456910315 1.950256518809788 0.0511455523630142 1.0 0.4398828321219025 28 O43464,Q99623,O95140,Q676U5,Q9NQ88,Q96HY6,P05141,P12235,Q9Y6I9,P27544,O94874,O15269,P21796,O15270,O75143 15 +Mitochondrial fusion 0.5785084896639897 1.9490509699831309 0.0512893380858523 1.0 0.4398828321219025 13 O95140,Q8TB36,Q9GZY8,O60313,Q9UJZ1,Q96E52,Q8IWA4,Q9NX63,Q9Y6C9 9 +Sphingoid metabolic process 0.7817491129593648 1.9484984017448563 0.0513553558743742 1.0 0.4398828321219025 5 Q06136,P04062,Q13510 3 +Vesicle fusion with golgi apparatus 0.7816257690378932 1.9479481458258496 0.0514211680721481 1.0 0.4398828321219025 5 Q9UEU0,O15155,Q13190 3 +Regulation of calcium ion transmembrane transport 0.5331422844141408 1.947266635825819 0.0515027764846953 1.0 0.439988773302048 18 P0DP25,P78417,P21796,Q96GC9 4 +Regulation of mitochondrion organization 0.4276855491756013 1.9463585726589496 0.0516116822563823 1.0 0.440327318686666 42 O43464,Q9H3K2,O14965,Q9GZY8,P05141,O60313,P12235,Q96A26,Q9UG56,Q96E52,O14737,O00429,P21796,Q9NUQ9,Q9H4A6,Q9Y6C9 16 +Regulation of neurotransmitter levels 0.4663269261563245 1.937029192845148 0.0527417749585852 1.0 0.4440942538182209 31 Q4J6C6,Q9P253,P0DP25,Q8NCG7,P16615,Q13277,Q7L0J3,O95721,P21964,P50897,Q99808 11 +Phosphatidylinositol biosynthetic process 0.4884082079727589 1.9370269070219053 0.0527420543605094 1.0 0.4440942538182209 25 Q08AM6,Q5H8A4,Q9BTU6,Q92643,Q8NEB9,Q96N66,Q9NX62,O60762,Q10713,Q9NTJ5 10 +Amine transport 0.7321827273980935 1.9365222996010285 0.0528037640824909 1.0 0.4440942538182209 6 Q15041,Q7L0J3,Q15042,P55011 4 +Regulation of amino acid transport 0.7321827273980935 1.9365222996010285 0.0528037640824909 1.0 0.4440942538182209 6 Q15041,Q7L0J3,Q15042,P55011 4 +Regulation of release of cytochrome c from mitochondria 0.6436247988609427 1.9355381068959272 0.0529242971338819 1.0 0.4440942538182209 10 Q9H3K2,Q9GZY8,O60313,Q96A26,O14737 5 +Positive regulation of oxidoreductase activity 0.7058169176798876 1.9331150673547433 0.0532220243499581 1.0 0.4448970047720096 8 P00374,P0DP25,P16435 3 +C terminal protein amino acid modification 0.9088804082861366 1.9312295016641423 0.0534546771793333 1.0 0.4458765461310275 4 O60725 1 +Calcium import into the mitochondrion 0.73042058405083 1.92815861878026 0.0538353995859892 1.0 0.4478767012677327 6 P21796,Q9H4I9 2 +Glycerolipid catabolic process 0.7038664076634934 1.9234701607060951 0.0544210304317243 1.0 0.4480033285220813 8 Q8NCC3,Q8NCG7,Q8WTV0,Q9NP80 4 +Regulation of cellular respiration 0.5294139121231126 1.9208790176553605 0.0547469615988329 1.0 0.4480033285220813 18 Q9NZ45,P14406 2 +Regulation of monooxygenase activity 0.7031241396366426 1.919797102930565 0.0548835329625694 1.0 0.4480033285220813 8 P0DP25,P16435,P00374,Q8TCT9,Q8WTV0 5 +Membrane biogenesis 0.4862366749583009 1.9195844478315711 0.0549104100435591 1.0 0.4480033285220813 25 Q96CP7,Q6NUK4,Q8IXJ6,O75192,Q9H6H4,Q86XL3 6 +Glycolipid biosynthetic process 0.6717053896411045 1.915665782682934 0.0554076504729723 1.0 0.4495658349925628 9 Q92643,Q5H8A4,Q99805,O60762,Q8NBX0 5 +Positive regulation of calcium ion transmembrane transport 0.6182783614179758 1.9145673937024523 0.0555476967376971 1.0 0.4495658349925628 11 P0DP25,Q96GC9 2 +Antigen processing and presentation of exogenous antigen 0.6703166885158535 1.9084023935150964 0.0563392277392786 1.0 0.4522944800397678 9 P04439,Q9UIQ6,Q03518,Q99538 4 +Post translational protein modification 0.5719742290544201 1.9078037788579791 0.0564165821867832 1.0 0.4522944800397678 13 P46977,Q676U5,Q9HA64,O60725 4 +Regulation of amyloid precursor protein catabolic process 0.5942664482769636 1.9040149263191857 0.0569082402511926 1.0 0.4547721467453419 12 O95197,Q9NQC3,P62942 3 +Leukocyte degranulation 0.704785199268455 1.8965786336258856 0.0578835727598434 1.0 0.4587897893730285 7 P09601 1 +Nuclear envelope organization 0.4601575196651957 1.883362410628506 0.0596512708184913 1.0 0.4698184353436564 31 Q6NUK4,Q8IXJ6,O14657,O94901,Q9H6H4,Q86XL3,Q8N1F7,O75844 8 +Iron ion homeostasis 0.5423706000129928 1.8806595138839668 0.0600182503724933 1.0 0.4717455409675193 16 P09601,Q9Y487,P30519 3 +Phosphatidylglycerol metabolic process 0.6122677663910145 1.8797831183011204 0.0601376421337458 1.0 0.4717455409675193 11 Q99623,Q8NCC3,Q8WUK0,O95674,Q9NP80,Q9UJZ1,P40939,Q8NF37 8 +Positive regulation of cysteine type endopeptidase activity 0.481095565603044 1.8781625997241496 0.0603589247979998 1.0 0.4718835498352856 25 O43464,Q9P0J0,Q9BXK5,Q9NZJ7,P51572,O75915,Q99538,Q96A26,O14737,Q9NR28,O95831 11 +Terpenoid metabolic process 0.5170578513687751 1.8712823158673109 0.0613059603636751 1.0 0.4751959561847799 19 Q9Y394,Q9HB40,P14324,Q9HBH5,Q8NBN7,P51648,P37268 7 +Regulation of nitric oxide synthase activity 0.7628599136010109 1.863884257775522 0.0623379598816404 1.0 0.4800033528804425 5 P00374,P0DP25,Q8WTV0 3 +Aminoglycan biosynthetic process 0.6615363484966195 1.8623445962286416 0.0625545331915209 1.0 0.4800033528804425 9 O43505,Q96L58,P06865,Q8NCH0,Q7LGA3 5 +Mannosylation 0.6910295407450852 1.8597405996514025 0.0629222349815963 1.0 0.4808394660111991 8 Q6ZXV5,O43505,Q9BT22,Q9BV10 4 +Neurotransmitter secretion 0.4971856882020046 1.8526502155765656 0.0639325099954337 1.0 0.4826354445842845 22 Q4J6C6,P0DP25,P16615,Q13277,Q7L0J3,O95721,P50897,Q9P253 8 +Regulation of cytokinesis 0.5031000147928446 1.8521284715597184 0.0640073769510589 1.0 0.4826354445842845 21 P0DP25,P41208 2 +Regulation of cation channel activity 0.5290515070536951 1.8515660960744125 0.0640881553223939 1.0 0.4826354445842845 17 P0DP25,P78417,P62942,P05067 4 +Oligodendrocyte development 0.7134302297981495 1.8471460866795764 0.064725970621513 1.0 0.4829947966470067 6 Q92542,Q9NR50 2 +Negative regulation of ion transmembrane transport 0.5538607358889387 1.8433873211174203 0.0652724799261927 1.0 0.4829947966470067 14 P0DP25,P78417,P21796 3 +Metal ion export 0.7115731743244587 1.838251048687905 0.0660254206647932 1.0 0.4829947966470067 6 P20020,P0DP25,O95202,P05023 4 +Mitochondrial protein processing 0.6914064394445937 1.8307519934205465 0.0671375687117408 1.0 0.4829947966470067 7 Q96E52,Q10713,Q99797 3 +Positive regulation of ryanodine sensitive calcium release channel activity 0.9654377880184332 1.8254098762016164 0.0679392000436436 1.0 0.484104882822196 2 P0DP25 1 +Lysosomal lumen acidification 0.882557638710585 1.8241608540292793 0.0681277577786447 1.0 0.4843624479206556 4 P50897,O75503 2 +Protein catabolic process in the vacuole 0.7517624975445282 1.813854255958556 0.0697001668806083 1.0 0.4904409435210713 5 P04062,Q8N511 2 +Lysosomal protein catabolic process 0.7517624975445282 1.813854255958556 0.0697001668806083 1.0 0.4904409435210713 5 P04062,Q8N511 2 +Positive regulation of monooxygenase activity 0.7509673527486738 1.8102606754272763 0.0702553722573684 1.0 0.4912465853331505 5 P00374,P0DP25,P16435 3 +Positive regulation of calcium ion transmembrane transporter activity 0.6807767054499453 1.8085262921275111 0.07052462856035 1.0 0.4920466949830787 8 P0DP25,Q96GC9 2 +Regulation of defense response to virus 0.5395200642963216 1.803205923154686 0.0713558806040739 1.0 0.4951287959819803 15 Q07021,O75844,O43657 3 +Phospholipid catabolic process 0.5976766953682489 1.794796165463787 0.0726861819872675 1.0 0.4989129294935985 11 Q8NCC3,Q8NHP8,Q9NP80,Q05655,Q8WTV0 5 +Respiratory electron transport chain 0.4079280535309979 1.7877804956285754 0.07381142883361 1.0 0.500524038734097 48 O75306,Q9H3K2,P03886,O14949,Q9UJS0,O96000,Q16134,O75438,O95168,O43676,O14548,Q9UDW1,P04062,Q7KZN9,P21912,P13073,P43304 17 +Dolichyl diphosphate biosynthetic process 0.9562211981566752 1.7865332777332177 0.0740129540640834 1.0 0.500524038734097 2 Q86YN1 1 +Neuromuscular process controlling balance 0.5749345288177996 1.786468834983489 0.0740233789191395 1.0 0.500524038734097 12 P17900,O14773,P10253,P05067 4 +Regulation of glycoprotein metabolic process 0.5741035626791023 1.7813834227817862 0.0748498344815533 1.0 0.5045021717547753 12 Q99805,P35610,Q9BXS4,Q9H0U4,Q92542 5 +Export across plasma membrane 0.6994067237969522 1.779782629585977 0.0751115414548431 1.0 0.5045675500313113 6 P20020,P0DP25,P54709,P05023,P08183 5 +Negative regulation of exocytosis 0.6810840464024542 1.7796580633418844 0.0751319375618249 1.0 0.5045675500313113 7 P09601 1 +Regulation of oxidative phosphorylation 0.6144940448382403 1.7730708521907146 0.0762169671597925 1.0 0.5045675500313113 10 P14406 1 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.5724617324172306 1.7713277663427751 0.0765062127209064 1.0 0.5045675500313113 12 Q9BXK5,Q9NZJ7,Q96A26 3 +Membrane fusion 0.4096441488444341 1.7699611431148707 0.0767336139758678 1.0 0.5045675500313113 43 Q86Y82,P56962,Q13190,O14653,O43752,Q9P2W9,Q13277,Q9UEU0,Q12981,O15155,O00429,O95249,P04083,O15400 14 +Proton transporting two sector atpase complex assembly 0.697045184552314 1.7683954496986218 0.0769948167518104 1.0 0.5053630410941257 6 Q15070,Q8N511 2 +Acidic amino acid transport 0.5927041179444337 1.7656582450770753 0.0774532019330418 1.0 0.5053630410941257 11 Q9H936,Q9UJS0,Q15042,O60831,Q15041,Q8TDW0,P55011 7 +Neural retina development 0.6962853821015256 1.7647291183331455 0.0776093023527921 1.0 0.5053630410941257 6 Q15555,P54802,Q8NBN7 3 +Golgi vesicle transport 0.3863235638211378 1.7639221549869482 0.0777450862289768 1.0 0.5053630410941257 134 O15258,P98194,P11279,P49755,Q96RQ1,Q9Y6B6,Q6NUQ1,O75396,Q5JRA6,Q9HCU5,Q9NR31,P24390,Q9Y282,P51572,Q9P2W9,Q9UEU0,P61026,Q9Y3B3,O14579,Q13190,O15260,Q9Y5U9,P61019,P56962,Q4J6C6,O43731,Q9HD47,O14653,O15127,Q15363,Q12981,O15155,O95249,Q9H4A6,Q9Y3A6,Q9H9E3,Q96PC5,Q12907,Q8NHH9,Q8TBA6,O43752,O95070,Q9H0U4 43 +C4 dicarboxylate transport 0.6718836745965261 1.7638823767307652 0.0777517845270934 1.0 0.5053630410941257 8 Q9H936,Q9UJS0,Q02978,Q8TDW0,Q9UBX3,P55011 6 +Regulation of mitophagy 0.6944627554383498 1.7559290919790675 0.0791005168047236 1.0 0.5088693166101451 6 Q9NQ88,P05141,P12235,P27544,P21796 5 +L glutamate transmembrane transport 0.6762040863771929 1.7554121811550354 0.0791888299838765 1.0 0.5089223492189275 7 O60831,Q15041,Q9H936,Q9UJS0 4 +Triglyceride metabolic process 0.6110834181176277 1.7538647036286177 0.0794536928762845 1.0 0.5098749730038472 10 P50416,Q86UL3,Q8NCG7,Q96N66,Q9UBV2,Q8WTV0 6 +Glycerophospholipid catabolic process 0.6755889152558199 1.7523516289879884 0.0797133634410931 1.0 0.5102297462553756 7 Q8NCC3,Q8WTV0,Q9NP80 3 +Adp transport 0.8646245059288626 1.7507009444687562 0.0799974366709623 1.0 0.5110188014880772 4 P05141,P12236,P12235 3 +Intracellular lipid transport 0.6093209476360403 1.7439248762617463 0.0811721902376196 1.0 0.5169643698900909 10 P50416,P23786,Q9H2C2,P61916,O15118 5 +Phosphatidylinositol metabolic process 0.4552516594201679 1.7418774596197897 0.0815298888852253 1.0 0.5173390493925769 27 Q08AM6,Q5H8A4,Q9BTU6,Q92643,Q8NEB9,Q96PE3,Q96N66,O14735,Q9NX62,O60762,Q96S52,Q10713,Q9NTJ5,Q92604 14 +Maternal process involved in female pregnancy 0.6384789700659453 1.740312483070524 0.0818041633012118 1.0 0.5183567970720757 9 Q8IZL8,P35613,Q9BQE5,Q15363 4 +Phosphatidic acid metabolic process 0.6906821580970441 1.7376524334256545 0.0822720748660978 1.0 0.5190855587364887 6 Q9NUQ2,Q9NPH0,Q86UL3,Q8NF37 4 +Oocyte maturation 0.7329054945784061 1.7283212425244792 0.0839306466710021 1.0 0.5197742100134704 5 Q15645,Q8IXJ6,Q9Y5A9 3 +Regulation of calcium ion transmembrane transporter activity 0.5359779785560148 1.726296183645278 0.0842941416000069 1.0 0.5197965338296242 14 P0DP25,P78417,Q96GC9 3 +Regulation of golgi organization 0.6642895308556724 1.7255982967653667 0.0844197060002109 1.0 0.5197965338296242 8 Q9P2W9,Q5T2E6 2 +Microglia differentiation 0.9410796576695196 1.722527347038571 0.084974033277456 1.0 0.5204423544967551 2 P05067 1 +Import across plasma membrane 0.5183591213518066 1.7164389227378145 0.0860817377780907 1.0 0.52600433362925 16 Q8N697,P54709,P31751,O75915,Q15758,P05023,P08195,Q15041,Q8TDW0,P55011 10 +Mitotic nuclear membrane organization 0.6853916177882948 1.712024334418769 0.0868921840476704 1.0 0.5262095053469891 6 Q86XL3,Q6NUK4,Q9H6H4 3 +Mitochondrial atp synthesis coupled proton transport 0.5829286364555812 1.7081220775556665 0.0876136931767113 1.0 0.528486815612661 11 P56134,P24539,P06576,O75964,Q9UJZ1,P00846,P56385 7 +Membrane protein proteolysis 0.5613728560361633 1.7031415320816483 0.0885415852176152 1.0 0.5304150006061851 12 Q8TCT9,Q9NZ08,Q8TCT8,Q92542 4 +Establishment of protein localization to organelle 0.4027464496367497 1.7001133745872818 0.0891096020214452 1.0 0.5311695563234113 180 O43464,Q99623,Q9NS69,Q9UGP8,Q8N4H5,Q99595,P11279,O60220,O60830,Q99832,Q14108,O15397,P57740,Q8N8Q8,P55060,Q10713,O14617,O00165,Q9P0J0,Q53FT3,Q9HAV7,Q9GZY8,Q8TEX9,P52789,Q92973,P62072,P51572,P46379,Q53H12,O43615,Q96RL7,O14737,P61026,Q9BW27,Q15388,O14925,Q9Y512,O95429,Q8N1F7,P52292,Q99797,Q15070,Q15005,O75381,O43681,Q9Y584,Q9HD47,Q3ZCQ8,P0DP25,Q7Z3B4,Q8NFH5,P49458,Q99523,Q9UHB9,Q5JRX3,Q9Y2T2,Q9Y5M8,P40855,P55786,O96008,Q9Y5J9,Q9H9H4,Q05655,O95373,O95831,Q9Y371,P50542,Q9H1Z9,Q96P70,Q15042,Q99442,Q9Y5Y5,Q15629,Q7Z4Q2 74 +Fatty acid transmembrane transport 0.6640290141773839 1.6946713696237516 0.0901377798002174 1.0 0.5314096560379482 7 P50416,P31751,P23786,O43772,P11166,P28288 6 +Cellular iron ion homeostasis 0.5599305227736734 1.6942382484489236 0.0902200194588136 1.0 0.5314096560379482 12 P09601,Q9Y487 2 +Neuromuscular process 0.458228977333363 1.691800060971672 0.0906841019808293 1.0 0.5314096560379482 25 P17900,P78417,O14773,P04062,P10253,O75844,P05067 7 +Response to increased oxygen levels 0.599955079805048 1.690935590256115 0.0908491049674808 1.0 0.5314096560379482 10 Q9Y487,P00846 2 +Amyloid beta formation 0.628381928968996 1.6863907039428463 0.0917205707674577 1.0 0.5331211004816393 9 Q16799,Q92542,Q9NQC3,O95197 4 +Peptidyl proline hydroxylation to 4 hydroxy l proline 0.722899505766057 1.6826798806816683 0.0924370785868105 1.0 0.5331211004816393 5 Q96HE7,P07237,P13674,O15460 4 +Regulation of hormone metabolic process 0.7228059999082667 1.6822525568257918 0.0925198766395181 1.0 0.5331211004816393 5 O75844,P16435 2 +Membrane protein ectodomain proteolysis 0.5981977849934318 1.6809620511437426 0.0927702859031593 1.0 0.5331211004816393 10 Q8TCT9,Q9NZ08,Q8TCT8 3 +Amide transport 0.4095514711928384 1.6778040346278982 0.0933853614656272 1.0 0.5331211004816393 39 Q15907,Q8N5M9,P07602,Q9NZJ7,O00400,Q9H2D1,Q03518,Q16836 8 +Positive regulation of calcium ion transport 0.5208611661455487 1.6777428634902725 0.0933973077732526 1.0 0.5331211004816393 15 P0DP25,P78417,O76024,Q96GC9 4 +Establishment of protein localization to endoplasmic reticulum 0.474380869543115 1.676727346552424 0.0935958105297578 1.0 0.5331211004816393 22 Q9Y5M8,O43681,Q9UGP8,P46379,P61026,Q99442,Q15042,Q9UHB9,Q15629,Q15005 10 +Atp synthesis coupled proton transport 0.556962306440681 1.6758914324596648 0.0937594601963016 1.0 0.5331211004816393 12 P56134,P24539,P06576,O75964,Q9UJZ1,P00846,P56385 7 +Negative regulation of macroautophagy 0.5772656640108891 1.6746390635557262 0.0940050699968007 1.0 0.5331211004816393 11 Q9NQ88,P09601,O75396,P42345,O15118 5 +Tail anchored membrane protein insertion into er membrane 0.6261620952925508 1.6744975537552118 0.0940328547691931 1.0 0.5331211004816393 9 O43681,P46379,Q5J8M3,Q15006,Q8N4V1,Q9NPA0 6 +Gpi anchor metabolic process 0.6594131223211259 1.6715515794646547 0.0946127796433007 1.0 0.5331211004816393 7 Q92643,Q5H8A4,Q9H490,O60762,Q96S52,O43292 6 +Synaptic vesicle exocytosis 0.4896029934306873 1.670389180621376 0.0948423888723628 1.0 0.5331211004816393 19 Q4J6C6,P0DP25,P16615,Q13277,Q7L0J3,O95721,Q06787,Q15042,Q9P253 9 +Neuron maturation 0.720104172717527 1.6698988174550191 0.0949393843590997 1.0 0.5331211004816393 5 Q9NZJ7,P05067 2 +Determination of adult lifespan 0.6766822158484161 1.6697054175929928 0.0949776613503075 1.0 0.5331211004816393 6 O75844 1 +Positive regulation of mitochondrial calcium ion concentration 0.7199091742574254 1.669006742126902 0.0951160436543858 1.0 0.5331211004816393 5 Q9BPX6,Q8IYU8,P51572 3 +Positive regulation of lipid metabolic process 0.5113328114296004 1.6678692518775222 0.0953416847461565 1.0 0.5331211004816393 16 P50416,Q8NCG7,P16435,Q9UJZ1,Q05655,P42345,P04083,Q8WTV0,Q92604 9 +Negative regulation of protein polymerization 0.4487042865517575 1.665989338399812 0.095715537982439 1.0 0.5337027841586182 26 Q9NUQ9,Q6ZU35,P45880 3 +Chemical homeostasis 0.3959688222547764 1.6654904209880084 0.0958149531374565 1.0 0.5337027841586182 169 Q15907,P98194,Q96CP7,Q9H4I9,Q15904,P09601,P55011,P20020,Q9Y6B6,Q9Y6N1,Q9UJZ1,O75880,P49366,P50897,Q9Y6C9,P62942,P61916,Q8NF37,Q9BPX6,Q96A33,P30519,O15254,P52789,Q96RR1,P51572,Q9HD20,Q96PU5,P04062,Q96HE7,Q9P246,Q9UM00,Q92544,Q99808,O75503,O15260,Q9NQC3,Q8N5M9,Q9HD47,P35610,P0DP25,P54709,P06576,O76024,P16615,Q15067,Q93050,Q9BWH2,Q8N511,Q9Y487,Q8WTV0,Q96TC7,Q8NE01,Q9P035,Q9HC07,Q8IYU8,P78417,Q16891,O95202,O75027,Q9NP80,P05023,Q7L0J3,Q9Y639,P05067,O15118 65 +Heparan sulfate proteoglycan biosynthetic process 0.6755646044506609 1.6642634973611232 0.0960597836811609 1.0 0.5337027841586182 6 Q96L58,Q7LGA3,Q99805 3 +Heparan sulfate proteoglycan metabolic process 0.6755646044506609 1.6642634973611232 0.0960597836811609 1.0 0.5337027841586182 6 Q96L58,Q7LGA3,Q99805 3 +Vesicle tethering 0.8432350860017899 1.662580413269029 0.0963964545200193 1.0 0.5343516373433266 4 Q14849 1 +Regulation of lipid metabolic process 0.3960608016103404 1.6623730578309568 0.0964379975025666 1.0 0.5343516373433266 48 Q99623,Q96G23,P07602,Q9NZJ7,Q96N66,Q9H2C2,Q9UJZ1,P61916,Q8NF37,Q9H6K4,P16435,Q13510,O75844,P50416,O94905,P42345,Q8WTV0,Q15118,Q8NCG7,P05023,Q05655,P04083,Q92604 23 +Response to ph 0.7179209359662656 1.6599073922009973 0.0969330841298696 1.0 0.5362112121231085 5 Q15907,P04062 2 +Regulation of leukocyte mediated cytotoxicity 0.6738097510910271 1.6557135090096726 0.0977798502619409 1.0 0.5394867432855004 6 Q9NUQ9,P11279,O15400 3 +Positive regulation of cell killing 0.6738097510910271 1.6557135090096726 0.0977798502619409 1.0 0.5394867432855004 6 Q9NUQ9,P11279,O15400 3 +Regulation of hormone levels 0.3815049281051919 1.6543773802600137 0.0980508594660429 1.0 0.5400821408542742 61 Q14849,Q15907,Q53GQ0,Q9Y394,Q8N5M9,O95470,Q9HB40,Q6NUM9,P16435,Q8NBQ5,P42892,P05023,Q9HBH5,Q8NBN7,Q96HE7,O75844,Q16836,P04083 18 +Negative regulation of ion transmembrane transporter activity 0.5934503664676671 1.6539692698182522 0.0981337567080882 1.0 0.5400821408542742 10 P0DP25,P78417 2 +Neurotransmitter transport 0.4446709917915482 1.6521514618044948 0.0985036783725556 1.0 0.5406644039170673 27 Q4J6C6,Q9P253,P0DP25,P16615,Q13277,Q7L0J3,O95721,P50897,Q99808 9 +Amyloid beta metabolic process 0.5733258131205053 1.6512794680555034 0.0986815227651161 1.0 0.5409687719483924 11 Q16799,Q92542,Q9NQC3,O95197 4 +Nuclear membrane reassembly 0.5524190870708492 1.6477460302267983 0.0994047980858914 1.0 0.5411221735033896 12 Q86XL3,Q6NUK4,Q9H6H4 3 +Positive regulation of triglyceride metabolic process 0.9233048057932852 1.647205983213237 0.0995157144310265 1.0 0.5411221735033896 2 Q8WTV0 1 +Regulation of synaptic vesicle exocytosis 0.5522524893671552 1.6467125063380004 0.0996171523815689 1.0 0.5411680517412415 12 Q4J6C6,P0DP25,P16615,Q06787,Q15042,Q9P253 6 +Cerebral cortex radially oriented cell migration 0.6484846685121393 1.645458371205919 0.0998753206562459 1.0 0.5416446570743166 8 Q9NQC3,Q96N66 2 +Telencephalon glial cell migration 0.6484846685121393 1.645458371205919 0.0998753206562459 1.0 0.5416446570743166 8 Q9NQC3,Q96N66 2 +Tetrapyrrole catabolic process 0.9479598275876996 1.6434021774605625 0.1002997499126365 1.0 0.5420962673849643 3 P09601 1 +Regulation of superoxide metabolic process 0.7136176253294785 1.64019071790696 0.1009655186643012 1.0 0.5443060531215427 5 P00374 1 +Antigen processing and presentation of peptide antigen 0.5299213338458599 1.6379783543871975 0.1014262092431081 1.0 0.5460016904814923 13 P10321,Q99538,P04439,Q9UIQ6,Q9NZ08,Q03518 6 +Glucosylceramide metabolic process 0.9203423304805796 1.6346364397675612 0.1021252839688213 1.0 0.546417999928463 2 P04062 1 +Positive regulation of i kappab kinase nf kappab signaling 0.4346630640409538 1.6332478475171317 0.102416880487266 1.0 0.546417999928463 30 Q5T9L3,O43657,P09601,Q86UE4,P62942 5 +Negative regulation of ion transport 0.5061915827098747 1.6321871797442988 0.1026400606720925 1.0 0.5468400885430177 16 P0DP25,P78417,P21796 3 +Intermembrane lipid transfer 0.7111104590558521 1.628689728291076 0.1033787183146812 1.0 0.5474633820431053 5 Q14849,P61916 2 +Regulation of ire1 mediated unfolded protein response 0.7110378912685252 1.6283566925416844 0.1034492748685873 1.0 0.5474633820431053 5 P18031,P57088,Q96HY6,Q92905 4 +Positive regulation of peptidyl threonine phosphorylation 0.6504823917992474 1.626681052596859 0.1038048549286037 1.0 0.5476913330072939 7 P0DP25 1 +Endoplasmic reticulum calcium ion homeostasis 0.6447620164290976 1.6264934284134973 0.1038447302077543 1.0 0.5476913330072939 8 Q96A33,O76024,P51572,P16615,P05067 5 +Regulation of nik nf kappab signaling 0.5208413304454947 1.62610677998577 0.1039269419768196 1.0 0.5476913330072939 14 O43657 1 +Regulation of transporter activity 0.3956338001288275 1.625814298641048 0.1039891656609719 1.0 0.5476913330072939 43 Q9HD47,P0DP25,P78417,Q96GC9,P27105,P62942,P05067 7 +Cell migration involved in sprouting angiogenesis 0.6497977237530322 1.6232336557367717 0.1045394658131084 1.0 0.548681126926604 7 P09601,P04083 2 +Antigen processing and presentation of endogenous peptide antigen 0.666050331874721 1.6178332752080802 0.1056985331784914 1.0 0.5516236439052356 6 Q9NZ08,P04439,Q03518 3 +Antigen processing and presentation of endogenous antigen 0.666050331874721 1.6178332752080802 0.1056985331784914 1.0 0.5516236439052356 6 Q9NZ08,P04439,Q03518 3 +Endochondral bone morphogenesis 0.665722140436147 1.6162284445701656 0.1060449310140121 1.0 0.5529299274200665 6 O75844,P16435 2 +Anterior posterior axis specification 0.6414609632667275 1.609648620067323 0.1074745875854759 1.0 0.5563723969960094 8 Q5T9L3,Q15363 2 +Glial cell migration 0.5462108942552193 1.609163922711928 0.1075805028175103 1.0 0.5563723969960094 12 Q96N66,Q9NQC3,Q96G23 3 +Regulation of cation transmembrane transport 0.3932647508893336 1.6063542435654552 0.10819609832676 1.0 0.5567633131839833 44 Q9HD47,P0DP25,P78417,Q96GC9,P21796,P62942,P05067 7 +Prostate gland growth 0.9134298880842616 1.6052928798803412 0.1084293653736905 1.0 0.5567633131839833 2 Q9NZJ7 1 +Negative regulation of transmembrane transport 0.4938070859781444 1.6029871634668176 0.1089374881514591 1.0 0.5567633131839833 17 P0DP25,P78417,P21796 3 +Transepithelial transport 0.7055108787104343 1.6029672018717864 0.1089418954014158 1.0 0.5567633131839833 5 P08183,Q86WC4,P55011 3 +Folic acid metabolic process 0.6456095516074508 1.6021230103343478 0.1091284105934351 1.0 0.5567633131839833 7 Q9H2D1 1 +Autophagosome maturation 0.4694550072623096 1.5961964777421207 0.1104449337666175 1.0 0.5611414860276749 21 P56962,Q8NEB9,Q96GC9,P16615,Q9UEU0 5 +Localization within membrane 0.3955884110262205 1.5935336948897345 0.1110405156134908 1.0 0.5632669730561434 181 O15258,O75122,Q15907,P98194,P43307,Q9NS69,O60220,P07602,Q9NZJ7,O60725,P35613,Q8N8Q8,P57105,Q9P0J0,Q96A33,Q9GZY8,Q99805,Q9HD45,Q53H12,P62072,O00264,Q9HD20,Q9UEU0,O14737,P61026,P27105,Q15006,Q9Y512,O00560,Q15070,O15400,Q4J6C6,Q9Y584,Q9HD47,P0DP25,Q7Z3B4,Q9UHB9,O43805,P40855,Q96L92,Q9BXS4,O43752,Q9Y5J9,Q9BTX1,Q13277,Q99442,Q9Y5Y5,Q8N4V1,Q15629,O15118 50 +Neutral lipid biosynthetic process 0.6605141727092797 1.5907336489443638 0.1116695308244872 1.0 0.5643783888552418 6 P33121,Q86UL3,Q8NCC3,Q8WTV0,Q92604 5 +Peptidyl proline hydroxylation 0.6102943533911735 1.5890902184465685 0.1120400258224629 1.0 0.5647314862232947 9 O75718,P07237,O15460,Q96HE7,P13674 5 +Regulation of autophagy 0.3478668577239202 1.5854211482371263 0.1128706793366569 1.0 0.5663178728378472 93 P07602,P09601,Q9NZJ7,P05141,Q86UE4,Q9NZ45,P12235,O15269,P04062,Q15382,O75844,Q676U5,Q8IXJ6,Q07820,Q93050,P10619,P21796,Q9Y487,Q8NEB9,Q9BXS4,O15118 21 +Leukotriene metabolic process 0.659287282477426 1.584719951545989 0.1130299767196241 1.0 0.5663178728378472 6 Q9UJ14,P09960 2 +Adult locomotory behavior 0.5068459715822496 1.582493635177162 0.1135369241785217 1.0 0.5663976410740588 15 P50897,O75844,P05067 3 +Sterol transport 0.4673267314371385 1.5797980264322142 0.1141531277422822 1.0 0.5663976410740588 21 Q86Y82,Q14849,Q9H2C2,Q96SU4,P61916,Q8WTV0,O15118 7 +Regulation of blood pressure 0.5059966914014152 1.576694976822569 0.1148657267691097 1.0 0.5663976410740588 15 Q9HB40,P09601,Q9NZ08,P42892 4 +Positive regulation of organic acid transport 0.6571372515320599 1.5741744782450908 0.1154471179146314 1.0 0.5675033886043293 6 Q15041,Q15042 2 +Regulation of macroautophagy 0.3823774668579269 1.570118670051328 0.1163875058481505 1.0 0.5694834389305963 54 P05141,P09601,Q8WVM8,O75396,Q9UHD9,P12235,O15269,P04062,Q15382,Q93050,P42345,P21796,O15270,Q9Y487,Q9NQ88,Q8NEB9,Q9Y371,Q15042,O15118 19 +Iron ion transport 0.5780898925333892 1.5661557997642617 0.117312147510119 1.0 0.5714688035764016 10 Q15907,O15173,Q8N4V1 3 +Acylglycerol homeostasis 0.9278893645044428 1.5650213357341365 0.1175779066851485 1.0 0.5714688035764016 3 Q9BWH2,Q9NP80 2 +Positive regulation of nitric oxide synthase activity 0.927889364504442 1.5650213357341345 0.117577906685149 1.0 0.5714688035764016 3 P00374,P0DP25 2 +Golgi vesicle budding 0.6972466843891121 1.5649166522372149 0.1176024535994231 1.0 0.5714688035764016 5 P49755,Q15363 2 +Er nucleus signaling pathway 0.503910229371649 1.562436460546332 0.1181852034153916 1.0 0.5734237808459764 15 Q6P1A2,Q96A33,O76024,P57088,Q15363,P16615,O75477,P18031,O94905,Q9UM00 10 +Sterol homeostasis 0.5764259752364597 1.5566007680956366 0.1195653013391182 1.0 0.5789914674562372 10 P61916,Q8WTV0,O15118 3 +Response to interleukin 12 0.899275839368003 1.545157583580152 0.122308151321167 1.0 0.5844868072951649 2 Q08722 1 +Regulation of leukocyte degranulation 0.8137522270820701 1.5403283183026455 0.1234803444012759 1.0 0.5874558899809208 4 P09601 1 +Outer mitochondrial membrane organization 0.6906556590430429 1.534498101803016 0.1249071598822477 1.0 0.589913127154717 5 O14737,Q9NS69 2 +Vesicle cargo loading 0.5536517220140995 1.533860174734405 0.1250640553574282 1.0 0.589913127154717 11 P49755,Q5JRA6,Q96PC5,Q9NR31 4 +Peroxisomal transport 0.6489312286693956 1.5338461707098507 0.1250675013108662 1.0 0.589913127154717 6 O75381,P40855,Q9Y5Y5,P28288 4 +Regulation of steroid metabolic process 0.5138443441349434 1.5329173852885696 0.1252962117147369 1.0 0.589913127154717 13 P05023,Q13510,Q9H2C2,P16435 4 +Positive regulation of tor signaling 0.6260547337308986 1.5306982015339488 0.1258439984789494 1.0 0.5907418421951275 8 Q15382,Q9Y4R8,Q9H4A6,Q9Y2Q5,Q9P2J5 5 +Negative regulation of amyloid precursor protein catabolic process 0.625753767062045 1.5291505320873533 0.1262271306380686 1.0 0.5917158529230707 8 Q9NQC3,O95197 2 +Positive regulation of release of sequestered calcium ion into cytosol 0.6473654843920784 1.5261373946921324 0.1269756508833772 1.0 0.5918249086498082 6 P0DP25 1 +Positive regulation of calcium ion transport into cytosol 0.6473654843920784 1.5261373946921324 0.1269756508833772 1.0 0.5918249086498082 6 P0DP25 1 +Ceramide transport 0.6886935967164305 1.5254310931330617 0.1271516083289463 1.0 0.5918249086498082 5 Q9NZJ7 1 +Mitophagy 0.5057411357290151 1.5252200875554844 0.1272042119068639 1.0 0.5918249086498082 14 O95140,Q99623,O43464,Q9NQ88,P05141,P12235,P27544,P21796,O75143 9 +Protein retention in er lumen 0.8100439096612495 1.5248954087036266 0.127285187244224 1.0 0.5918249086498082 4 P24390,O43731 2 +Maintenance of protein localization in endoplasmic reticulum 0.8100439096612495 1.5248954087036266 0.127285187244224 1.0 0.5918249086498082 4 P24390,O43731 2 +Atp metabolic process 0.3500480689584833 1.5205922328062305 0.1283621971803659 1.0 0.5949021362156137 103 Q9BSK2,Q9H3K2,P03886,O14949,Q9BRR6,P52789,P24539,O96000,Q9NTK5,O75964,O43676,P14406,Q9UDW1,P00846,Q7KZN9,P13073,P05067 17 +Protein lipid complex subunit organization 0.687572184949206 1.5202464965012734 0.1284490354563279 1.0 0.5949021362156137 5 Q6P1A2,P35610,Q8WTV0 3 +Leukocyte mediated cytotoxicity 0.5311775468141228 1.515170269506874 0.1297292900339155 1.0 0.5970741256014244 12 Q9NUQ9,P04439,P11279,O15400 4 +Cellular response to oxygen levels 0.4067278554100605 1.513785328336578 0.1300802949363533 1.0 0.5977340078747514 35 Q99623,O75306,Q8IXJ6,Q9NQ88,Q15904,Q15118,P09601,P55786,Q9Y4P3,Q96A26,P07237,P42345,Q8N511,Q96HE7,Q9Y487,Q99808 16 +Regulation of lipase activity 0.5687287069519252 1.512294342769797 0.1304589995922618 1.0 0.5979509631829362 10 Q99623,P16435,P04083,P50897,P40616 5 +Calcium ion import into sarcoplasmic reticulum 0.8897300855826054 1.5045761609411323 0.1324330790262287 1.0 0.5993454126134471 2 O75844 1 +Regulation of triglyceride metabolic process 0.9124135660190968 1.5044446815226689 0.1324669068336914 1.0 0.5993454126134471 3 Q8NCG7,Q8WTV0 2 +Cell maturation 0.4624625466903578 1.5037456104551734 0.1326468803982008 1.0 0.5993454126134471 20 Q8IXJ6,Q9NZJ7,Q9Y5A9,P04062,Q15645,P05067,O75503 7 +Ire1 mediated unfolded protein response 0.642690704809194 1.503095804626763 0.1328143405377888 1.0 0.5993454126134471 6 P18031,P57088,Q96HY6,Q92905 4 +Autophagosome membrane docking 0.8046772068511256 1.502541308038989 0.1329573681222404 1.0 0.5993454126134471 4 P16615,P56962,Q96GC9 3 +Regulation of generation of precursor metabolites and energy 0.3954983081379395 1.502105040565269 0.1330699833252444 1.0 0.5993886480008795 38 Q9NZ45,Q9BSK2,P14406,P05067 4 +Hormone biosynthetic process 0.6197665002686173 1.4983209546222862 0.1340498823364622 1.0 0.6016210898368782 8 Q14849,P05023,Q53GQ0,P16435 4 +Diol biosynthetic process 0.6188049055668006 1.493362322944019 0.1353423698186826 1.0 0.6023618588199846 8 P00374,P04062,Q13510 3 +Diol metabolic process 0.6188049055668006 1.493362322944019 0.1353423698186826 1.0 0.6023618588199846 8 P00374,P04062,Q13510 3 +Positive regulation of release of cytochrome c from mitochondria 0.6401335609375396 1.4904758332995005 0.136099166166586 1.0 0.6023618588199846 6 Q96A26,O14737,Q9GZY8 3 +Lipid homeostasis 0.4279941082076576 1.490411909675609 0.1361159629293389 1.0 0.6023618588199846 26 O15260,Q96CP7,O15254,Q9NQC3,Q9NP80,Q9BWH2,Q9Y6C9,P61916,Q8WTV0,O15118 10 +Regulation of ion transmembrane transport 0.3740220014927997 1.4874887949533615 0.1368857604478217 1.0 0.6023618588199846 55 Q9HD47,P0DP25,P78417,Q96GC9,P21796,O75844,P62942,P05067 8 +Olefinic compound metabolic process 0.4650187614560728 1.4872107821064986 0.1369591492436737 1.0 0.6023618588199846 19 Q14849,Q9Y394,Q6NUM9,Q8NCG7,P07099,Q9NP80,O95864,Q8NBN7,Q9HBH5 9 +Positive regulation of mitophagy 0.8003302783340795 1.4844189322579244 0.1376978152224357 1.0 0.6023618588199846 4 P12235,P21796 2 +Glycoside metabolic process 0.5906431257069027 1.4824051382152448 0.1382325276171081 1.0 0.6023618588199846 9 P06280,Q9NUJ1,P04062,Q9BTY2,P08236 5 +Ether biosynthetic process 0.6780889621087304 1.4763364362427054 0.1398535973289674 1.0 0.6023618588199846 5 O00116,Q6IAN0,Q7L5N7,P49327 4 +Glycosylceramide metabolic process 0.904511030622322 1.473476677956309 0.1406225479509626 1.0 0.6026459698160672 3 Q05655,P04062 2 +Glycosylceramide catabolic process 0.904511030622322 1.473476677956309 0.1406225479509626 1.0 0.6026459698160672 3 Q05655,P04062 2 +Cotranslational protein targeting to membrane 0.4973298918839693 1.4686392582352883 0.1419306607310497 1.0 0.6066652855457648 14 P43307,Q9UGP8,Q99442,Q9UHB9,Q15629 5 +Regulation of secretion 0.3365641541754262 1.46702787763947 0.1423684718946753 1.0 0.6077192796256258 89 O75122,Q16850,P11279,P49755,P09601,Q8N183,Q8NE86,O43633,Q8WUM4,P61026,P40939,P00367,O00560,Q5T9L3,Q9Y5U9,P50416,Q4J6C6,Q8N5M9,P0DP25,P16615,O00429,Q9H4A6,Q9P253,P04083,Q96KC8,Q8NEB9,Q7L0J3,Q06787,Q15042,Q16836,P55011 31 +Gliogenesis 0.3739516087186694 1.4658107231432076 0.1426998589254153 1.0 0.6083167695036487 53 O75306,P08670,Q9NQC3,Q96G23,Q8IXJ6,Q9NR50,Q96N66,P04062,Q15382,O94901,P04083,Q92542,P05067 13 +Sphingomyelin metabolic process 0.6350194846512796 1.4652039725951689 0.142865276084386 1.0 0.6085137447704988 6 Q9NXE4,Q05655,O15269 3 +Exocytic process 0.4664747998481409 1.4645882814104376 0.1430332811024426 1.0 0.6085137447704988 18 Q13277,Q9UEU0,Q7L0J3,P61026,O95721,Q9P253 6 +Cellular response to exogenous dsrna 0.6184235412080445 1.4641912985729637 0.1431416870523087 1.0 0.6085676006049997 7 Q9NUD5,Q08211,Q7Z434,Q5KU26 4 +Regulation of cell killing 0.6177670972127156 1.4608425862749437 0.1440586457571551 1.0 0.6104245016216518 7 Q9NUQ9,P11279,O15400 3 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.6323692755447016 1.45209081603339 0.1464763552303376 1.0 0.6119130951647017 6 Q5J8M3,Q15006,Q9NPA0,Q8N4V1 4 +Homologous chromosome segregation 0.5573191765001353 1.4463130579687091 0.1480894148813922 1.0 0.6143970763617032 10 Q9BXW9,Q15645,Q9BTX1,O94901,Q92791 5 +Amino acid import across plasma membrane 0.6709885737088852 1.443386011162207 0.1489117625208442 1.0 0.6165810673465264 5 Q15041,P08195,O75915 3 +Pyrimidine containing compound transmembrane transport 0.8966084952255455 1.4424910913090294 0.1491638829878316 1.0 0.6168416657583983 3 Q9BSK2,Q9HC21 2 +Vesicle targeting 0.4392586944575596 1.4417779913210231 0.1493650135577657 1.0 0.617264278759434 23 Q14849,O75122,O95772,P49755,Q15363,O95721,Q9HCU5,Q9NR31 8 +Smad protein signal transduction 0.6083510223023573 1.4393308313343471 0.1500568114513694 1.0 0.6185221099772399 8 P08670,O00400,Q9UIQ6 3 +Response to endoplasmic reticulum stress 0.3292732917361965 1.4362884892577523 0.1509202680783989 1.0 0.6208732840817501 82 Q9BUN8,Q7Z2K6,Q92575,O75955,P27824,P18031,Q9UBV2,Q6P1A2,Q96A33,Q9H8Y8,Q9UHD9,O95881,P57088,P51572,P46379,P07237,Q13217,Q96HE7,Q9UM00,Q92905,Q6ZXV5,O76024,O60313,Q9Y4P3,Q15363,P16615,Q9UBU6,O94905,Q9H3N1,Q96HY6,O15027,Q96CS3,O94874,O75477,P60604,O95831,Q8TCT9 37 +Glutamate receptor signaling pathway 0.7885990411529296 1.4354469497798066 0.1511597752956404 1.0 0.6214563594948838 4 Q8NCG7,P05067 2 +Regulation of programmed necrotic cell death 0.6279190337744656 1.4300462498511917 0.152703745384215 1.0 0.6230260286551302 6 Q13510 1 +Endoplasmic reticulum to cytosol transport 0.5166653525183087 1.423717758328667 0.1545281909677438 1.0 0.6255931094210062 12 Q9BUN8,Q9UBV2,Q8TCT9 3 +Reticulophagy 0.6664857661541465 1.4224598237033963 0.1548928068164712 1.0 0.6262714250162157 5 Q9Y6I9 1 +Maintenance of location 0.3577264584362697 1.4212935247995526 0.1552314451755951 1.0 0.6272416182683299 64 O15258,Q9H6V9,P10253,P62942,P24390,P52789,P17900,O95674,P04062,O94901,Q96HE7,Q14534,P50416,O43731,P35610,P0DP25,Q8WTV0,P78417,O95202 19 +Intracellular sterol transport 0.6259512795513985 1.420289180996179 0.1555235095771463 1.0 0.6276237630935505 6 Q9H2C2,O15118 2 +Negative regulation of defense response to virus 0.6255347901827573 1.4182232841317215 0.1561255860261376 1.0 0.6288556557554696 6 O43657 1 +External encapsulating structure organization 0.4173628320084757 1.4172216798998851 0.1564181251448677 1.0 0.6289952698513055 27 O75122,Q9Y5U9,O75718,Q53GQ0,Q92791,Q96HE7,P05067,P13674 8 +Cellular response to arsenic containing substance 0.6039649655136979 1.4165958239573249 0.1566011301822363 1.0 0.629012470293452 8 P09601 1 +Cellular response to increased oxygen levels 0.6088709126600611 1.415383015028577 0.1569562268542188 1.0 0.629012470293452 7 P49327,Q9Y487,Q8N511,Q15904 4 +Positive regulation of cation channel activity 0.6079898750190166 1.4108732721324455 0.1582819844433851 1.0 0.632729744101985 7 P0DP25,P78417 2 +Negative regulation of secretion 0.4547503298463285 1.40986085480138 0.1585807733153246 1.0 0.6335257040805803 19 Q16850,Q16836,Q8N5M9,P09601 4 +Glycosyl compound catabolic process 0.5501612623822875 1.4047413478018604 0.1600982056735949 1.0 0.6370853691491697 10 P06280,Q9NUJ1,Q13126,P04062,Q9BTY2,P08236 6 +Cellular macromolecule localization 0.3024530214902152 1.4037243549107423 0.1604009471247711 1.0 0.6370853691491697 528 Q86Y82,O75122,P98194,P43307,Q9NS69,Q8N4H5,Q9UGP8,Q99595,P49755,O60830,O60725,P18031,P50402,P57105,Q5JRA6,Q9HCU5,Q9NPA0,Q53FT3,P24390,Q9Y282,P62072,P51572,Q9P2W9,O43615,Q96PU5,Q9Y3B3,Q9BW27,O14925,Q15070,Q15005,Q99797,Q5T9L3,Q676U5,Q9NQC3,Q9Y584,Q9HD47,Q3ZCQ8,P0DP25,O43592,Q8NFH5,Q15363,Q15555,P10619,Q15041,Q9UHB9,Q9H4A6,Q9Y3A6,Q92643,P67809,O43805,O14965,Q8NEB9,O43752,Q9Y371,Q96P70,Q15042,Q8TCT9,Q15629,Q9BUN8,Q15907,O43464,Q99623,Q15904,Q9Y6B6,Q15154,Q8N8Q8,Q9Y6C9,P40616,O00165,Q14168,P50748,Q96A33,Q9HAV7,Q9H8Y8,Q8TEX9,Q9HD45,P46379,Q9HD20,Q96RL7,O14737,P27105,Q15388,P53680,O00560,O95429,Q92544,Q8NEY8,O43731,Q5JRX3,Q9Y2T2,Q9Y5M8,P40855,Q969Q5,Q9Y5J9,O95373,Q05655,Q8N4V1,O15118,P11279,O60220,Q99832,Q14108,Q9C0E2,Q10713,O14773,Q9NR31,Q9P0J0,P52789,O00264,P61026,O75381,Q13190,O14657,Q96HY6,Q96L92,Q9BXS4,Q13277,P55786,Q9H1Z9,Q7Z4Q2,O15258,P35613,O15397,Q9UBV2,Q99729,Q9GZY8,Q99805,Q92973,Q53H12,Q9UEU0,Q15006,O94901,Q9Y512,Q8N1F7,P52292,O15400,O15260,P56962,Q4J6C6,Q9UH62,Q7Z3B4,O00429,Q9P253,Q08211,O96008,Q99442,Q9Y5Y5,Q9H0U4 148 +Positive regulation of macroautophagy 0.4538850101063404 1.403321766449671 0.1605209103230509 1.0 0.6370853691491697 19 P05141,P09601,P12235,O15269,P21796,Q9Y371,Q15042 7 +Cellular lipid metabolic process 0.389982928477651 1.4020750522772183 0.1608928359859773 1.0 0.6370853691491697 204 Q86YN1,Q99735,Q8NBX0,P50897,Q9NZ01,Q9NXE4,Q9BTU6,O95674,Q13510,P51648,O75844,P50416,Q9HB40,P04066,P35610,Q9NPH0,O94905,O95864,Q92643,Q8NEB9,Q15800,O60762,Q9NP80,Q96S52,O43464,Q99623,Q5H8A4,Q96G23,Q86SQ9,Q9NZJ7,P23786,Q9UG56,Q9BV10,Q8NBN7,Q9BT22,A1L0T0,Q08AM6,O95470,P17900,P16435,P04062,P07099,Q9NUQ2,Q8WTV0,Q9P035,Q9BWD1,Q8NCG7,Q8NHP8,Q05655,P06865,Q16836,P07602,Q96N66,Q10713,Q06136,O15254,P06280,P16278,Q96PU8,Q5T2R2,Q53GQ0,Q9UKU0,Q8N4Q0,Q9HBH5,P04083,Q8IVS2,Q9Y394,Q8WUK0,Q9H2C2,P14324,Q9UBV2,P61916,Q8NF37,O43808,Q99805,Q8NCC3,Q53H12,O15269,Q8IXJ6,Q9NX62,Q15067,Q9NTJ5,P37268,Q6NUM9,Q9HBU6 85 +Protein depalmitoylation 0.780609704896668 1.402048769310042 0.1609006838464237 1.0 0.6370853691491697 4 P50897 1 +Lipoprotein catabolic process 0.780609704896668 1.402048769310042 0.1609006838464237 1.0 0.6370853691491697 4 P50897 1 +Maintenance of location in cell 0.3783929795207523 1.4009963821849694 0.1612151549658833 1.0 0.6376375388694179 40 O15258,P24390,O43731,P52789,P0DP25,P78417,P10253,O94901,Q96HE7,P62942 10 +Membrane protein intracellular domain proteolysis 0.8857425090549835 1.3998666801661512 0.1615532454751336 1.0 0.6377797560266522 3 Q8TCT9,Q8TCT8 2 +Pyramidal neuron differentiation 0.8854854477807864 1.398858126825958 0.1618555314078218 1.0 0.6377797560266522 3 O14949 1 +Regulation of cysteine type endopeptidase activity 0.3730723229754891 1.3983033014185031 0.1620220069052094 1.0 0.6377797560266522 45 Q9P0J0,P51812,Q96K76,Q9BXK5,Q9NZJ7,P51572,Q99538,P16435,Q96A26,O14737,Q15418,Q15392,Q9NR28,Q15041 14 +Electron transport chain 0.3498237418740539 1.3959986842801295 0.1627148913581937 1.0 0.6377797560266522 68 Q9Y6N1,O96000,Q9UDW1,Q7KZN9,Q9P0J0,Q9H3K2,O14949,Q16134,O75438,P16435,P04062,P21912,P13073,P03886,Q9H936,O43676,O14548,O15460,O75306,Q9UJS0,O95168,P43304 22 +Granulocyte differentiation 0.6050622807477348 1.3958783681318117 0.162751125771503 1.0 0.6377797560266522 7 P49327,O00165,Q14739,Q8N5M9 4 +Nik nf kappab signaling 0.4649445895352037 1.3951539080804682 0.1629694328400142 1.0 0.6377797560266522 17 O43657 1 +Mitochondrial ribosome assembly 0.7786203840618777 1.3937276828189658 0.1633998533742167 1.0 0.6380208845680782 4 Q9NUL7 1 +Triglyceride biosynthetic process 0.6602965403624245 1.393660745140041 0.1634200755312824 1.0 0.6380208845680782 5 Q8WTV0,P33121,Q86UL3,Q92604 4 +Positive regulation of lipid biosynthetic process 0.5736721612502376 1.3895247062795242 0.1646732534883352 1.0 0.6392712413432114 9 Q05655,Q8WTV0,P16435 3 +Attachment of gpi anchor to protein 0.6589785831960411 1.3875231520002274 0.1652822964127946 1.0 0.6409605100669451 5 Q9H490,Q92643,O43292,Q96S52 4 +Amino acid import 0.6189848384970268 1.385700750528748 0.16583829893105 1.0 0.6412729792288188 6 O75915,Q15758,P08195,Q9H9B4,Q15041 5 +Magnesium ion transport 0.86175115207373 1.385634476576325 0.165858545153398 1.0 0.6412729792288188 2 Q8N4V1 1 +Positive regulation of protein dephosphorylation 0.4912453630268271 1.3836355882525833 0.1664700654710127 1.0 0.6428212248686251 13 P0DP25,Q05655,P04062 3 +Long chain fatty acyl coa biosynthetic process 0.6017714407874211 1.3790059011645075 0.1678929344494419 1.0 0.645960951186836 7 Q9UKU0,Q53GQ0 2 +Release of sequestered calcium ion into cytosol by endoplasmic reticulum 0.7746714516125108 1.3772045106316178 0.1684490276758481 1.0 0.6473602571815866 4 P0DP25 1 +Leukotriene biosynthetic process 0.774662713346439 1.3771679405440929 0.1684603312426595 1.0 0.6473602571815866 4 Q9UJ14,P09960 2 +Icosanoid biosynthetic process 0.5088690897190745 1.3743186418039213 0.1693427814232453 1.0 0.6487495348400496 12 Q8NCG7,P09960,Q9NP80,P04083,Q9UJ14 5 +Response to oxidative stress 0.3320948443085322 1.373915150644524 0.1694680255202072 1.0 0.6487495348400496 92 O43169,Q99720,P09601,Q15392,P30519,Q96P47,Q6NUK1,P07237,P04062,Q9NR28,Q96HE7,Q8IXJ6,Q07820,Q15165,P16615,P00374,O75306,O95168,Q9NP80,Q05655,P04083,Q9UJ14,Q8N0U8,P05067 24 +Homologous chromosome pairing at meiosis 0.570792081888675 1.3736994285894066 0.1695350143718248 1.0 0.6487495348400496 9 Q9BXW9,Q15645,Q9BTX1,O94901,Q92791 5 +Phosphatidylserine metabolic process 0.6553352533983362 1.3705479126691946 0.1705159297445186 1.0 0.6510212209084499 5 Q6P1A2,Q8NCC3,P48651 3 +Regulation of mitochondrial membrane permeability 0.4892276027197886 1.3702237448651209 0.1706170682872265 1.0 0.6510212209084499 13 P52789,P12235,P45880 3 +Epithelial cell differentiation involved in prostate gland development 0.8781262479345686 1.3699837571307028 0.1706919720645388 1.0 0.6510212209084499 3 Q9NZJ7 1 +Protein mannosylation 0.7727029125052072 1.3689653074675157 0.171010119608479 1.0 0.6510212209084499 4 Q6ZXV5,O43505 2 +Protein o linked mannosylation 0.7727029125052071 1.3689653074675128 0.1710101196084799 1.0 0.6510212209084499 4 Q6ZXV5,O43505 2 +Endothelial cell proliferation 0.460869887042023 1.3655394119933362 0.1720835746474129 1.0 0.6529929554978847 17 P57105,P09601 2 +Negative regulation of peptidyl tyrosine phosphorylation 0.5988366935444046 1.3639444174128856 0.1725850598543257 1.0 0.6541148720537234 7 O95684,Q05655,P63244 3 +Adaptive thermogenesis 0.423823113770292 1.3591825135746212 0.1740887609603953 1.0 0.6566814033615864 24 P12235,P23786,Q96E52,Q9UIQ6,Q15382,Q16836 6 +Positive regulation of protein exit from endoplasmic reticulum 0.7700922266139629 1.358036183301046 0.1744522030843358 1.0 0.6573205139955131 4 Q9Y6B6,P51572,Q9NR31 3 +Interferon gamma production 0.5975279285654768 1.3572233185556362 0.1747102636043633 1.0 0.6576843315204682 7 Q07021,Q08722,Q9NUQ9 3 +Regulation of platelet activation 0.8739542048194526 1.3536144631747342 0.1758594101927808 1.0 0.6599408128815365 3 Q9BWH2 1 +Positive regulation of autophagy 0.4056914807277755 1.3534727607798789 0.1759046463877809 1.0 0.6599408128815365 29 Q676U5,P05141,P09601,Q9BXS4,P12235,Q86UE4,P21796 7 +Keratan sulfate metabolic process 0.8738887059598242 1.3533574808227582 0.1759414540480479 1.0 0.6599408128815365 3 P16278,P15586 2 +Notch signaling pathway 0.4468560563152082 1.3500916504760654 0.1769865862768682 1.0 0.660604439321246 19 Q96T37,P57105,Q9UBV2,Q92542,P05067 5 +Ribonucleoside metabolic process 0.5910527264688934 1.349456626390381 0.1771903429447037 1.0 0.660604439321246 8 O60725 1 +Purine ribonucleoside metabolic process 0.5910527264688934 1.349456626390381 0.1771903429447037 1.0 0.660604439321246 8 O60725 1 +Mitochondrion endoplasmic reticulum membrane tethering 0.8722799900894933 1.3470458438813129 0.1779654683388862 1.0 0.660604439321246 3 Q96GC9 1 +Maintenance of protein localization in organelle 0.4793213962843236 1.346653542033187 0.1780918413790437 1.0 0.660604439321246 14 O15258,P52789,P24390,O43731 4 +Nad biosynthesis via nicotinamide riboside salvage pathway 0.8525345622119822 1.346495227295408 0.1781428585583095 1.0 0.660604439321246 2 Q9BQG2 1 +Pyridine nucleotide biosynthetic process 0.8525345622119822 1.346495227295408 0.1781428585583095 1.0 0.660604439321246 2 Q9BQG2 1 +Mitochondrial adp transmembrane transport 0.8715837998024313 1.344314478393149 0.1788467156415498 1.0 0.6614877838622129 3 P12236,P12235 2 +Nucleobase transport 0.8715837998024304 1.3443144783931444 0.1788467156415514 1.0 0.6614877838622129 3 Q9Y277,P12235 2 +Locomotory behavior 0.4068451636580133 1.343969815509075 0.1789581478474828 1.0 0.6614877838622129 28 O43464,O15118,O75844,P04080,Q96RL7,P51790,P10253,P42345,P50897,P05067,P54802 11 +Dna replication checkpoint signaling 0.6490684304718435 1.341321423206689 0.1798161171396941 1.0 0.6614877838622129 5 Q9Y619 1 +Cellular sodium ion homeostasis 0.7658102766798447 1.340105675780714 0.1802109910966329 1.0 0.6614877838622129 4 P05023,Q96PU5,P55011 3 +Mitochondrial fission 0.4783457296260356 1.3400141013032076 0.180240760495975 1.0 0.6614877838622129 14 O14965,Q8NE86,Q9GZY8,O60313,O00429,Q9NUQ9,Q9UDX5 7 +Autophagosome organization 0.3912027998412518 1.3377248433448192 0.1809861493969149 1.0 0.6614877838622129 34 Q86Y82,Q676U5,P56962,Q9UHD9,Q8NEB9,Q96GC9,P16615,O75396,P04062,Q9Y371,Q15042,Q9H0U4 12 +Lipid storage 0.4567238660081155 1.335344336490692 0.1817636739210932 1.0 0.6614877838622129 17 Q14534,P17900,Q9H6V9,P04062 4 +Regulation of calcium ion transport into cytosol 0.5636584460945638 1.3344292759423269 0.1820632107919737 1.0 0.6614877838622129 9 P0DP25,P78417 2 +Regulation of release of sequestered calcium ion into cytosol 0.5636584460945638 1.3344292759423269 0.1820632107919737 1.0 0.6614877838622129 9 P0DP25,P78417 2 +Negative regulation of transporter activity 0.5205851628132373 1.33386398012161 0.1822484381838942 1.0 0.6614877838622129 11 P0DP25,P78417 2 +Positive regulation of protein localization to membrane 0.4097297889179655 1.3334725787205033 0.1823767683989741 1.0 0.6614877838622129 26 O15258,Q9GZY8,Q9HD47,O00264,Q13277,O14737,P27105 7 +Multi multicellular organism process 0.4052303853393247 1.329705093687748 0.1836154559209295 1.0 0.6614877838622129 28 Q8IZL8,Q9BQE5,Q96GC9,Q07021,P35613,Q15363,Q9UIQ6,P15291,Q96EP5 9 +Long chain fatty acid metabolic process 0.4254061233894072 1.329294228850646 0.1837509175303691 1.0 0.6614877838622129 23 P50416,Q96PU8,O14734,Q8NCG7,P07099,P23786,Q9UKU0,Q9NP80,O95864,P28288 10 +Sphingosine biosynthetic process 0.7630299121142906 1.328460146380494 0.1840261410764314 1.0 0.6614877838622129 4 P04062,Q13510 2 +Icosanoid transport 0.8674713175722002 1.3281810800272065 0.1841182931700054 1.0 0.6614877838622129 3 Q9NP80 1 +Arachidonic acid secretion 0.8674713175722002 1.3281810800272065 0.1841182931700054 1.0 0.6614877838622129 3 Q9NP80 1 +Cardiac septum morphogenesis 0.6451400329489262 1.3229843435050763 0.1858405845004949 1.0 0.6614877838622129 5 O96028,P04637,O94813,Q96T37 4 +Tyrosine catabolic process 0.8469387755101948 1.3227520722085748 0.1859178404996173 1.0 0.6614877838622129 2 O43708 1 +Phenol containing compound catabolic process 0.8469387755101836 1.3227520722085269 0.1859178404996333 1.0 0.6614877838622129 2 P21964 1 +Regulation of endoplasmic reticulum tubular network organization 0.6450878572598113 1.322740718406321 0.1859216175082239 1.0 0.6614877838622129 5 Q15041,P57088 2 +Negative regulation of actin filament polymerization 0.4388868702077156 1.3226751986639382 0.1859434147182979 1.0 0.6614877838622129 20 Q9NUQ9,Q6ZU35 2 +Ganglioside catabolic process 0.8653595911456182 1.3198976546562418 0.1868691907529776 1.0 0.6614877838622129 3 P17900 1 +Ganglioside metabolic process 0.8653595911456182 1.3198976546562418 0.1868691907529776 1.0 0.6614877838622129 3 P17900 1 +Glycolipid transport 0.8649983536384529 1.3184807475056743 0.1873427657777577 1.0 0.6614877838622129 3 P07602,Q9NZJ7 2 +Synaptic vesicle localization 0.4999708479943038 1.3177268571945602 0.1875951005656992 1.0 0.6614877838622129 12 Q96A57 1 +Regulation of phospholipase activity 0.5897705853297475 1.3173333408242809 0.1877269141309707 1.0 0.6614877838622129 7 Q99623,P50897,P04083 3 +Regulation of calcium ion transport 0.4036900027067148 1.3160850082683535 0.188145512182118 1.0 0.6614877838622129 28 P0DP25,P78417,P21796,Q96GC9 4 +Calcium ion transport into cytosol 0.499391990594443 1.3140380813596433 0.1888333893038509 1.0 0.6614877838622129 12 P0DP25,P78417,Q96HE7,P62942 4 +Dermatan sulfate metabolic process 0.8443054641211098 1.3115851980136015 0.1896601300143032 1.0 0.6614877838622129 2 Q8NCH0 1 +Dermatan sulfate biosynthetic process 0.8443054641211098 1.3115851980136015 0.1896601300143032 1.0 0.6614877838622129 2 Q8NCH0 1 +Dermatan sulfate proteoglycan metabolic process 0.8443054641211098 1.3115851980136015 0.1896601300143032 1.0 0.6614877838622129 2 Q8NCH0 1 +Regulation of inflammatory response 0.3961335253410166 1.3098843450541684 0.1902349638733789 1.0 0.6614877838622129 31 Q9BXW9,Q96KB5,Q08211,Q99735,P28070,Q8NCG7,Q08722,Q05655,P04062,P04083,P05067 11 +T cell mediated cytotoxicity 0.6032713897009668 1.3074481395641568 0.1910605570562218 1.0 0.6614877838622129 6 Q9NUQ9,P04439,O15400 3 +Nuclear pore organization 0.4797376274324874 1.3069801946455353 0.1912194379472112 1.0 0.6614877838622129 13 Q8N1F7,Q7Z3B4,Q9NQC3,Q9BTX1 4 +Neutrophil differentiation 0.7578598636322462 1.3068006986481897 0.1912804078434029 1.0 0.6614877838622129 4 Q14739 1 +Regulation of protein localization to cell surface 0.5333382456350263 1.3065440324624518 0.1913676151977563 1.0 0.6614877838622129 10 Q13277,Q15907,Q96PU5,Q9HD47 4 +Lipopolysaccharide mediated signaling pathway 0.6029504080291253 1.3058466280742211 0.1916047196966959 1.0 0.6614877838622129 6 Q86UE4 1 +Astrocyte development 0.6028509239696487 1.3053502382094455 0.1917736146014197 1.0 0.6614877838622129 6 P05067 1 +Protein maturation by protein folding 0.6413066304678198 1.30507985734438 0.1918656567920194 1.0 0.6614877838622129 5 P62942,O76024 2 +Nucleobase containing compound transport 0.3379138422348202 1.3033190324793855 0.1924658660113893 1.0 0.6614877838622129 108 Q9HC21,P05141,L0R6Q1,P12236,Q9H2D1,O43808,P41208,Q9BSK2,P12235,Q08722,O00400,Q6NUK1,Q9BW27,Q8N1F7,Q99808,Q96PU8,O43592,Q7Z3B4,Q8NFH4,Q8NFH5,P22626,P67809,Q08211,Q92945,Q9BTX1,Q8TDW0,Q8TB61 27 +Nuclear membrane organization 0.4270469638641098 1.3025328661012217 0.1927342903543973 1.0 0.6614877838622129 22 Q6NUK4,Q8IXJ6,O14657,P50402,Q9H6H4,Q86XL3 6 +Regulation of steroid biosynthetic process 0.5578400871816995 1.302327029216524 0.1928046155965412 1.0 0.6614877838622129 9 P05023,Q13510,P16435 3 +O glycan processing 0.7567841183895498 1.3022933376774122 0.1928161282816609 1.0 0.6614877838622129 4 Q10472,O43505 2 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.7567624121205547 1.3022023868144974 0.1928472094865765 1.0 0.6614877838622129 4 Q03518,Q9UIQ6 2 +Phosphatidylcholine catabolic process 0.8607178136318667 1.3016929198153473 0.1930213808894618 1.0 0.6617166342466673 3 Q8WTV0,Q9NP80 2 +Phosphate ion transport 0.7552700922266216 1.2959492984729375 0.1949929532206997 1.0 0.6624132606471232 4 Q00325,Q9UBX3,O43826 3 +Phosphate ion transmembrane transport 0.7552700922266216 1.2959492984729375 0.1949929532206997 1.0 0.6624132606471232 4 Q00325,Q9UBX3,O43826 3 +Response to estrogen 0.4963915501786833 1.2949041277297606 0.1953533043932784 1.0 0.662743879262144 12 P09601,P04062 2 +Protein localization to lysosome 0.4963689381256362 1.2947598442967885 0.1954030883790525 1.0 0.662743879262144 12 Q9NQC3,Q9Y2T2 2 +Receptor localization to synapse 0.4961581434557776 1.293414741030335 0.1958676544572823 1.0 0.663307758247658 12 Q13277,P57105,Q9Y639,O15400 4 +Er overload response 0.6387241456616328 1.293012484121487 0.1960067413533326 1.0 0.663307758247658 5 Q96A33,O76024 2 +Synaptic vesicle transport 0.5134004442157571 1.2900268958634162 0.1970413198968463 1.0 0.6647529879322481 11 Q96A57 1 +Regulation of long term synaptic potentiation 0.5555106673158243 1.2894574548646198 0.1972390981347884 1.0 0.6650324251485722 9 Q99538,Q9Y639,Q9BPZ3,Q92542,P05067 5 +Cerebral cortex cell migration 0.5124230404923367 1.284054194513524 0.1991229936374763 1.0 0.6676007445926032 11 Q9NQC3,Q96N66 2 +Heme transport 0.8377221856484325 1.2836887479605554 0.1992508830226822 1.0 0.6676007445926032 2 O15173 1 +Iron coordination entity transport 0.8377221856484325 1.2836887479605554 0.1992508830226822 1.0 0.6676007445926032 2 O15173 1 +Regulation of hormone biosynthetic process 0.8370638578011678 1.2809008879588228 0.2002284808949688 1.0 0.6684477338384041 2 P16435 1 +Regulation of steroid hormone biosynthetic process 0.8370638578011678 1.2809008879588228 0.2002284808949688 1.0 0.6684477338384041 2 P16435 1 +Positive regulation of striated muscle contraction 0.8370638578011639 1.2809008879588064 0.2002284808949745 1.0 0.6684477338384041 2 P78417 1 +Antigen processing and presentation of peptide antigen via mhc class i 0.5114006859831437 1.2778045610492763 0.2013183457975329 1.0 0.6701612328132953 11 P10321,P04439,Q9UIQ6,Q9NZ08,Q03518 5 +Protein targeting to peroxisome 0.6353846944884811 1.2774020603303842 0.2014603377559036 1.0 0.6701612328132953 5 O75381,P40855,Q9Y5Y5 3 +Positive regulation of mitochondrion organization 0.4235196838882194 1.2742306906724588 0.2025816714349273 1.0 0.6701612328132953 22 O14965,Q9GZY8,P05141,P12235,Q96A26,O14737,O00429,P21796 8 +Positive regulation of amino acid transport 0.7497649143275444 1.2728796352083502 0.203060756758151 1.0 0.6701612328132953 4 Q15041,Q15042 2 +Positive regulation of amine transport 0.7497649143275444 1.2728796352083502 0.203060756758151 1.0 0.6701612328132953 4 Q15041,Q15042 2 +Long term synaptic potentiation 0.4746013668379434 1.2726448542387612 0.2031440943573441 1.0 0.6701612328132953 13 Q99538,Q13277,Q9Y639,Q9BPZ3,Q92542,P05067,Q14168 7 +Negative regulation of intracellular estrogen receptor signaling pathway 0.7496706192358369 1.2724844709322765 0.20320103815945 1.0 0.6701612328132953 4 Q92600,Q99623,Q9P253 3 +Positive regulation of anion transport 0.5804498993055687 1.2692952743108137 0.2043357711993894 1.0 0.6701612328132953 7 Q15041,Q15042,P55011 3 +Lipid metabolic process 0.3931975965802033 1.269101105982568 0.2044050058922979 1.0 0.6701612328132953 269 Q86YN1,Q99735,Q9BQE5,Q99538,Q8NBX0,Q9H6V9,P49356,P50897,Q9NZ01,Q9NXE4,Q14849,Q9BTU6,O95674,Q13510,Q8NBQ5,P15291,O75844,P51648,P50416,Q9HB40,P04066,P35610,Q9NPH0,O94905,O95864,P21964,Q92643,Q8NEB9,Q15800,O60762,Q9NP80,Q06520,Q96S52,Q14739,P05067,O43464,Q99623,Q5H8A4,Q96G23,Q86SQ9,Q9NZJ7,P23786,Q9UG56,Q9BV10,Q15392,Q8NBN7,Q9BT22,A1L0T0,Q08AM6,Q9H6K4,O95470,P17900,P16435,P04062,Q14534,P07099,P09960,Q9NUQ2,P00387,Q8WTV0,Q9P035,P38435,Q9BWD1,Q8NCG7,Q8NHP8,Q05655,Q96SU4,P06865,Q16836,O15118,Q16850,P07602,Q96N66,Q96E52,Q10713,Q06136,O14773,O15254,P06280,P16278,Q96PU8,Q5T2R2,Q53GQ0,Q9UKU0,Q8N4Q0,Q9HBH5,P04083,Q8IVS2,Q9Y394,Q8WUK0,Q9H2C2,P14324,Q9UBV2,P61916,Q8NF37,O43808,Q99805,Q8NCC3,Q53H12,O15269,Q8IXJ6,Q9NX62,Q15067,P16930,Q9NTJ5,P37268,Q6NUM9,P05023,Q9HBU6 109 +Monocarboxylic acid transport 0.5797835824875293 1.2658569949803926 0.2055642853963664 1.0 0.6716732105824007 7 P04083,Q9NP80 2 +Mitochondrial genome maintenance 0.5510567033945459 1.264824291909945 0.2059343213548417 1.0 0.6716732105824007 9 P51530,Q9BSK2,P12235 3 +Xenobiotic metabolic process 0.5090635027126222 1.2635089508394588 0.2064063319097107 1.0 0.6718329725524034 11 O43169,P78417,P16435 3 +Signal release 0.3524899289837279 1.2627539047315457 0.2066776350995049 1.0 0.6719401783593113 57 Q15907,Q8N183,P50897,Q8NE86,P16870,P00367,P40939,Q5T9L3,Q4J6C6,P50416,Q8N5M9,P0DP25,P16615,O95721,Q9P253,P04083,Q13277,Q7L0J3,Q06787,Q15042,Q16836 21 +Photoreceptor cell differentiation 0.6311222254592056 1.2574683771489226 0.2085840829161642 1.0 0.6749389858413404 5 P54802,Q8NBN7 2 +Regulation of organic acid transport 0.5247412862579314 1.2561234933516243 0.2090711995416727 1.0 0.6752876424090419 10 O75915,Q7L0J3,Q15041,Q15042,P55011 5 +Multicellular organism aging 0.5731201913629184 1.2557536569421548 0.2092052985733918 1.0 0.6752876424090419 8 O75844,P04062 2 +Peptidyl glutamic acid modification 0.630699292963006 1.255490040653849 0.2093009212627143 1.0 0.6752876424090419 5 Q8N0U8 1 +Mitochondrial proton transporting atp synthase complex assembly 0.7454312841565107 1.254718516392724 0.2095809615300223 1.0 0.6753593991915164 4 Q15070 1 +Response to arsenic containing substance 0.490074806428308 1.2545506497329768 0.2096419280372659 1.0 0.6753593991915164 12 P09601 1 +Positive regulation of lipid catabolic process 0.744400527009243 1.2503989363819958 0.211153852936742 1.0 0.6785807296706231 4 Q8NCG7,P50416,Q05655 3 +Positive regulation of fatty acid metabolic process 0.7444005270092197 1.250398936381898 0.2111538529367778 1.0 0.6785807296706231 4 P50416,P04083,Q92604 3 +Forebrain cell migration 0.489203453189486 1.2489769423347028 0.2116735074254783 1.0 0.6798366918627287 12 Q9NQC3,Q96N66 2 +Ether metabolic process 0.5761753785091357 1.2472294211317445 0.2123133879954648 1.0 0.6806107803768775 7 Q6IAN0,O00116,P07099,Q7L5N7,P49327 5 +Organic hydroxy compound biosynthetic process 0.3552227211855316 1.246950255994269 0.2124157377192885 1.0 0.6806107803768775 52 Q16850,Q14534,Q86SQ9,Q15800,Q9H2C2,P16435,P00387,P14324,O15269,P04062,Q15392,Q13510,P00374,Q14739,Q96SU4 15 +Positive regulation of pattern recognition receptor signaling pathway 0.5474604691056171 1.2449113270845833 0.2131643467651187 1.0 0.6811019397504933 9 Q9NQC3 1 +Eye photoreceptor cell differentiation 0.7430812837962353 1.2448704926236156 0.2131793588917285 1.0 0.6811019397504933 4 Q8NBN7,P54802 2 +Small gtpase mediated signal transduction 0.3228876627811129 1.244567273079879 0.2132908565078641 1.0 0.6811019397504933 77 Q9P035,P80303,Q9HD47,P09601,P61225,Q15382,Q15392,P57105,O00560,Q02818,Q9NUQ9 11 +Positive regulation of hydrolase activity 0.3164231347214337 1.243186618570317 0.2137990725874452 1.0 0.6818398923059719 83 O43464,Q99623,P07602,Q9NZJ7,P31751,Q99538,P40616,Q9P2J5,Q9P0J0,Q9BXK5,P51572,P49327,O14737,P61289,Q9NR28,Q8TC07,Q8IZ81,P0DP25,Q96A26,Q15555,P42345,Q92542,Q66K14,Q96HY6,O75915,Q05655,O95831,Q15042,P05067 29 +Export from cell 0.3494107975767042 1.237573372437046 0.2158742927974002 1.0 0.6841299310832016 135 O75122,Q15907,Q16850,P11279,P49755,P09601,P20020,P27824,Q8N183,Q5JRA6,P50897,Q9HCU5,Q8NE86,Q9UBV2,O43633,Q8WUM4,P16870,Q8TBQ9,Q9UEU0,P08183,P61026,P40939,P00367,O14936,O00560,Q5T9L3,Q9Y5U9,P50416,P56962,Q4J6C6,Q8N5M9,P0DP25,P54709,P16615,O95721,O00429,O43760,Q9H4A6,Q9P253,P04083,Q96PC5,O15126,Q96KC8,Q8NEB9,Q9BRK5,Q13277,Q7L0J3,P05023,Q06787,Q15042,Q7Z6M1,Q16836,P55011 53 +Protein localization to endoplasmic reticulum exit site 0.6268079135392405 1.2372840269499488 0.2159816557513201 1.0 0.6841299310832016 5 Q5JRA6,P51572 2 +Myeloid leukocyte activation 0.4502909712983885 1.2372475242771197 0.2159952029641876 1.0 0.6841299310832016 16 P09601,Q05655,P05067 3 +Adult behavior 0.427766467716828 1.236492401275073 0.2162755885253535 1.0 0.6844411032053753 20 O75844,P50897,P05067,O15118 4 +Positive regulation of erbb signaling pathway 0.6260414711614379 1.2336975227824156 0.2173156373598688 1.0 0.6855497388673858 5 Q9NQC3 1 +Walking behavior 0.740199426629947 1.232794272978932 0.2176525285819837 1.0 0.6855497388673858 4 O75844,O15118 2 +Positive regulation of endoplasmic reticulum unfolded protein response 0.8255431204739925 1.2321749610555166 0.2178837344577915 1.0 0.6855497388673858 2 P57088 1 +Positive regulation of ire1 mediated unfolded protein response 0.8255431204739925 1.2321749610555166 0.2178837344577915 1.0 0.6855497388673858 2 P57088 1 +Maternal placenta development 0.6255035877410516 1.231180424536616 0.2182553911351055 1.0 0.6857297410057986 5 P35613,Q15363 2 +Cardiolipin metabolic process 0.5878239000816787 1.2302619847009464 0.2185990150275731 1.0 0.6864700294047703 6 Q99623,Q9UJZ1,Q8WUK0,Q9NP80 4 +Integrated stress response signaling 0.5875546906428069 1.228915049745729 0.2191036582108765 1.0 0.6866976585741278 6 P18031,Q96E52,P57088 3 +Regulation of vacuole organization 0.4680129773454275 1.2285036963965748 0.2192579426436074 1.0 0.6868425251073281 13 Q9UHD9,Q14108,O75396,Q9Y371,Q15042,Q9H0U4 6 +Regulation of ion transport 0.3268577205101515 1.225477968057716 0.2203951862263635 1.0 0.6871165845645132 74 Q15907,Q99623,Q9BVC6,P62942,Q96PU5,P27105,O75844,Q9P246,O76024,Q9HD47,P0DP25,Q96GC9,P21796,Q15041,P05067,P78417,P05023,Q7L0J3,Q15042,P55011 20 +Regulation of cardiac muscle contraction by calcium ion signaling 0.737710362502691 1.2223648909499858 0.2215696699611395 1.0 0.6896479014058833 4 P0DP25,P78417 2 +Cartilage development involved in endochondral bone morphogenesis 0.737645419744531 1.22209278897559 0.2216725397376053 1.0 0.6896479014058833 4 O75844 1 +Calcium mediated signaling 0.4471368005674779 1.2146455373560392 0.2245013129169293 1.0 0.6954073612971708 16 P0DP25,P78417,O75844 3 +Fatty acid elongation 0.8212639894667395 1.2141104704136607 0.224705542251169 1.0 0.6955780551896603 2 Q9P035 1 +Sphingomyelin catabolic process 0.8209348255431077 1.2127217417856198 0.2252362244325232 1.0 0.6955780551896603 2 Q05655 1 +Growth plate cartilage development 0.8379992219035247 1.2126969002546308 0.2252457253995707 1.0 0.6955780551896603 3 O75844 1 +Bone growth 0.8379992219035247 1.2126969002546308 0.2252457253995707 1.0 0.6955780551896603 3 O75844 1 +Apoptotic mitochondrial changes 0.3897789447516541 1.210788503007053 0.2259764725922737 1.0 0.6965598738101318 29 Q9H3K2,Q9GZY8,P05141,P52789,O60313,P12235,P45880,Q96A26,O14737 9 +Regulation of multicellular organism growth 0.4462643145207425 1.2083890291242068 0.2268976577388111 1.0 0.6971610450548638 16 O43464,Q86UL3,O95470,Q99538,O75844,P05067 6 +Receptor recycling 0.5679527559329285 1.2047292168856458 0.2283078531555653 1.0 0.6979916857415938 7 Q15907 1 +Ketone biosynthetic process 0.5673846167247255 1.2017903568992487 0.2294447625207174 1.0 0.6985947925653188 7 Q14849 1 +Regulation of cholesterol biosynthetic process 0.6190282473367632 1.200871998009811 0.2298008579039123 1.0 0.6985947925653188 5 O75477,O94905,P16435 3 +Regulation of alcohol biosynthetic process 0.6190282473367632 1.200871998009811 0.2298008579039123 1.0 0.6985947925653188 5 O75477,O94905,P16435 3 +Brown fat cell differentiation 0.5812137697300217 1.197175667749494 0.2312380917507694 1.0 0.6995475065054216 6 O75192,Q96HE7,Q02252 3 +Mitochondrial electron transport cytochrome c to oxygen 0.580923203723776 1.1957206646652498 0.2318055844460753 1.0 0.7000154042064524 6 P20674,P13073,O14548,Q7KZN9 4 +Protein localization to extracellular region 0.3416234563310193 1.1955517001054432 0.2318715494722543 1.0 0.7000154042064524 62 Q15907,Q16850,P49755,P27824,Q5JRA6,Q9UBV2,Q9HCU5,Q8TBQ9,P61026,Q9Y5U9,Q5T9L3,P50416,Q8N5M9,O00429,Q9H4A6,Q96PC5,Q96KC8,Q8NEB9,P04083,Q16836 20 +Mitochondrial respirasome assembly 0.7308913413755751 1.193799136508367 0.2325565495365162 1.0 0.7011999188112417 4 P14406,Q9BW72 2 +Macroautophagy 0.329367355492616 1.190600203714012 0.2338105716202867 1.0 0.7028618920409759 107 Q86Y82,O43464,Q99623,Q8WVM8,P09601,P36543,P05141,Q9Y6I9,O75396,O95140,Q9UHD9,Q6PHR2,P12235,Q9UEU0,O15269,P04062,Q15382,Q676U5,P56962,Q96GC9,P16615,Q93050,O95721,P42345,P21796,O15270,Q9Y487,Q9NQ88,Q96HY6,Q8NEB9,Q9H9H4,Q9Y371,Q15042,Q9H0U4,O15118 35 +Organic hydroxy compound transport 0.3932426050723374 1.1903900149793556 0.2338931357407325 1.0 0.7028618920409759 26 Q86Y82,Q14728,Q14849,P35610,Q9H2C2,Q96SU4,P61916,Q8WTV0,O15118 9 +Manganese ion transport 0.8310833058939653 1.185657962857231 0.2357574018954742 1.0 0.705828566390784 3 Q9HD20,Q9HC07 2 +Manganese ion transmembrane transport 0.8310833058939653 1.185657962857231 0.2357574018954742 1.0 0.705828566390784 3 Q9HD20,Q9HC07 2 +Positive regulation of proteolysis 0.3122644703482176 1.18356759892472 0.2365842726997375 1.0 0.7073665152869576 83 O43464,Q9NZJ7,Q99538,Q9P0J0,Q9UHD9,Q9BXK5,P51572,P46379,O14737,P04062,P61289,Q9NR28,P53634,P48729,Q6ZXV5,Q8IXJ6,Q96A26,Q92542,O14965,Q96HY6,Q9UBS8,O75915,Q9Y5A7,Q06787,P05067 25 +Oligosaccharide metabolic process 0.5638528437298562 1.1835153328020145 0.2366049734896274 1.0 0.7073665152869576 7 P10253,P17900,P06280,P15291 4 +Lipid catabolic process 0.3218444453308095 1.1811820551037528 0.2375304084145031 1.0 0.7085718632248175 75 O14734,Q99735,P23786,Q9H6V9,P50897,P28288,O43808,A1L0T0,Q9NXE4,O15254,P06280,O95470,Q8NCC3,P17900,Q16134,P04062,Q13510,Q8NBQ5,P50416,Q8IXJ6,P35610,P04066,Q15067,Q8WTV0,Q9BWD1,Q8NCG7,Q8NHP8,Q9NP80,Q06520,Q05655,P06865,Q8IVS2,Q16836 33 +Estrogen biosynthetic process 0.8130348913759027 1.1794317546457844 0.2382262967744806 1.0 0.7095021474659332 2 Q53GQ0 1 +Disaccharide metabolic process 0.812705727452272 1.1780464104396018 0.2387781045087953 1.0 0.7096862311742438 2 P10253 1 +Regulation of protein exit from endoplasmic reticulum 0.5766418099185747 1.1742767549104638 0.2402841908598656 1.0 0.7100168838239451 6 Q9NR31,Q9Y6B6,P51572,Q92544 4 +Vitamin d metabolic process 0.8274613105037789 1.171510591086495 0.241393603189421 1.0 0.7102047593288983 3 P38435,P04062 2 +Cerebellar purkinje cell layer development 0.5756004717786837 1.1690598312072962 0.2423795263413588 1.0 0.7102047593288983 6 P04062,O14949 2 +Arachidonic acid metabolic process 0.5603635851325226 1.1654511356648711 0.2438364287205008 1.0 0.7102047593288983 7 P07099,Q9NP80 2 +Regulation of neurotransmitter transport 0.4402642045281431 1.1653140016705117 0.2438919135083743 1.0 0.7102047593288983 16 Q4J6C6,P0DP25,O14936,P16615,Q06787,Q15042,Q9P253 7 +Positive regulation of granulocyte chemotaxis 0.6112761282331508 1.1645790539221814 0.2441894264886042 1.0 0.7102047593288983 5 Q07021,O00429,Q8NHP6 3 +Positive regulation of neutrophil migration 0.6112761282331508 1.1645790539221814 0.2441894264886042 1.0 0.7102047593288983 5 Q07021,O00429,Q8NHP6 3 +Nerve development 0.5600881799363374 1.1640249876854456 0.2444138855407087 1.0 0.7102047593288983 7 Q9H061 1 +Protein localization to vacuole 0.4222055074606466 1.1620228142834006 0.2452261979280523 1.0 0.7102047593288983 19 Q9NQC3,Q14108,Q96RL7,Q9H9H4,Q9Y371,Q99523,Q9Y2T2 7 +Organic hydroxy compound metabolic process 0.3305345419673103 1.1614606909987035 0.2454546000791078 1.0 0.7102047593288983 112 Q16850,Q86SQ9,Q9Y394,Q9BQE5,Q9H2C2,P14324,Q10713,Q15392,Q8NBN7,P61916,Q14849,P16435,O15269,P04062,Q13510,P51648,Q14534,Q9NX62,P00387,P16930,P21964,P00374,Q8WTV0,P37268,P38435,Q15800,Q14739,Q96SU4,Q9HBH5,P05067,O15118 31 +Positive regulation of response to endoplasmic reticulum stress 0.5592291600775773 1.1595763636123957 0.2462213289796069 1.0 0.7103870935063011 7 P18031,P57088,P51572,Q9UHD9 4 +Chloride transmembrane transport 0.722002635046112 1.1565857261692678 0.2474416567386095 1.0 0.7115096512214621 4 Q9UHG3,P51790,P55011 3 +Regulation of cell migration involved in sprouting angiogenesis 0.7217735502331997 1.15562708995778 0.2478337223917475 1.0 0.7116655686470119 4 P09601 1 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.5582979062252124 1.1547531507468896 0.2481915271148547 1.0 0.7116655686470119 7 Q9NUD5,O43657 2 +Regulation of cytosolic calcium ion concentration 0.4212230925453 1.1544905662161495 0.2482991040085793 1.0 0.7116655686470119 19 P0DP25,P78417,P51572,O95202,Q9Y639,Q96HE7,P62942 7 +Release of cytochrome c from mitochondria 0.4503142020592998 1.1481601172583458 0.2509024702835174 1.0 0.7162289339477156 14 Q9H3K2,Q9GZY8,O60313,Q96A26,O14737,O00429 6 +Cell recognition 0.3985189083641187 1.148046949145205 0.2509491828036641 1.0 0.7162289339477156 24 Q9NQC3,P45880,Q99832,Q8WTV0,P05067 5 +Tor signaling 0.4240833507632115 1.1474608529338062 0.2511912034656445 1.0 0.7162289339477156 18 P04062,Q15382,Q9H4A6,O75844,Q9P2J5 5 +Retinal rod cell differentiation 0.8051349572086908 1.1462257803470357 0.251701743416576 1.0 0.7162289339477156 2 P54802 1 +Retinal rod cell development 0.8051349572086908 1.1462257803470357 0.251701743416576 1.0 0.7162289339477156 2 P54802 1 +Camera type eye photoreceptor cell differentiation 0.8051349572086908 1.1462257803470357 0.251701743416576 1.0 0.7162289339477156 2 P54802 1 +Cellular response to biotic stimulus 0.3711605101857017 1.1461348241379663 0.2517393704278157 1.0 0.7162289339477156 34 Q96A33,P08670,O76024,Q86UE4,Q9NUQ9,O75844,Q8WTV0 7 +Negative regulation of blood circulation 0.8198418274204008 1.1417840501647183 0.2535437937434661 1.0 0.718788739087186 3 P16615 1 +Linoleic acid metabolic process 0.803489137590494 1.1393195941653091 0.2545698787413042 1.0 0.7197381277992269 2 Q9NP80 1 +Regulation of metal ion transport 0.3473524102697225 1.1387522941436627 0.2548064845525675 1.0 0.7197381277992269 49 Q9HD47,P0DP25,P78417,Q96GC9,P21796,P62942 6 +Protein o linked glycosylation via threonine 0.8028308097432348 1.1365583189788224 0.2557229727866255 1.0 0.7201000628057703 2 Q10472 1 +Positive regulation of cell migration involved in sprouting angiogenesis 0.8184420485871811 1.136328614484304 0.2558190594423268 1.0 0.7201000628057703 3 P09601 1 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.817823219748844 1.1339174155759404 0.2568291911073568 1.0 0.7207092002994966 3 O75844 1 +Mammary gland development 0.422090517784564 1.1324197070378923 0.2574580235016901 1.0 0.7215268505408415 18 Q13505,Q99623,Q9UNS2,Q9NQC3,Q86UL3,P52789,P31751,Q99808 8 +Lysosomal transport 0.3556508863785166 1.1324123314472392 0.2574611228802121 1.0 0.7215268505408415 39 P11279,Q96L92,P07602,Q9NZJ7,Q14108,Q9Y2T2,O15118 7 +Pyrimidine nucleoside triphosphate metabolic process 0.453379270096015 1.130125586045727 0.2584233099042075 1.0 0.7230481178633545 13 Q9UIJ7 1 +Retrograde transport vesicle recycling within golgi 0.8011849901250812 1.1296581957056653 0.2586202787477929 1.0 0.7230481178633545 2 Q8TBA6 1 +Posttranslational protein targeting to endoplasmic reticulum membrane 0.5490280201600547 1.1292242147473597 0.2588032612605833 1.0 0.7230481178633545 8 Q99442,P46379,Q9UGP8 3 +Positive regulation of protein autophosphorylation 0.5533513938447643 1.1291259707227028 0.2588446970457547 1.0 0.7230481178633545 7 P0DP25 1 +Positive regulation of dephosphorylation 0.4472604433062788 1.1271550021223844 0.2596769518001425 1.0 0.7240908282748564 14 P0DP25,Q05655,P04062 3 +Calcium ion export 0.7144672986320665 1.1250681361806032 0.2605601624494087 1.0 0.7240908282748564 4 P0DP25,O95202 2 +Icosanoid metabolic process 0.4093358467170103 1.1250502958411732 0.2605677218483424 1.0 0.7240908282748564 21 Q8NCG7,P07099,P09960,Q8N4Q0,Q9NP80,Q15067,P04083,Q9UJ14 8 +Positive regulation of t cell mediated cytotoxicity 0.7142699566138683 1.1242431846768637 0.2609098737920388 1.0 0.7240908282748564 4 Q9NUQ9,O15400 2 +Regulation of t cell mediated cytotoxicity 0.7142699566138683 1.1242431846768637 0.2609098737920388 1.0 0.7240908282748564 4 Q9NUQ9,O15400 2 +Positive regulation of transporter activity 0.4091764005285615 1.123783545657239 0.2611048635567652 1.0 0.7240908282748564 21 P0DP25,P78417,Q96GC9 3 +Regulation of cell maturation 0.7988808426596452 1.1200055666867663 0.2627113899144568 1.0 0.7263130031736789 2 Q8IXJ6 1 +Regulation of oocyte maturation 0.7988808426596452 1.1200055666867663 0.2627113899144568 1.0 0.7263130031736789 2 Q8IXJ6 1 +Positive regulation of cell maturation 0.7988808426596452 1.1200055666867663 0.2627113899144568 1.0 0.7263130031736789 2 Q8IXJ6 1 +Tyrosine metabolic process 0.8141409824198397 1.119577848821892 0.2628936993974442 1.0 0.7265010232044155 3 O43708 1 +Positive regulation of glycoprotein metabolic process 0.5470019057287868 1.1185599710691236 0.2633279084690236 1.0 0.7272686787516267 8 Q9H0U4,Q92542 2 +Positive regulation of proteasomal ubiquitin dependent protein catabolic process 0.3900298156494708 1.1178977091322588 0.2636106835840561 1.0 0.7272686787516267 25 P48729,Q8IXJ6,Q96HY6,Q9UHD9,Q9UBS8,P51572,P04062 7 +Intracellular distribution of mitochondria 0.8126440566348312 1.1137524423793588 0.2653854044728829 1.0 0.7288510324816746 3 O75153,O00429 2 +Regulation of aerobic respiration 0.4393566060944838 1.11371533478346 0.2654013284942977 1.0 0.7288510324816746 15 P14406 1 +Erad pathway 0.3563427748017893 1.108611863430489 0.2675976580772183 1.0 0.7305245944306724 38 Q9BUN8,Q96A33,O76024,Q9UHD9,Q92575,P51572,P27824,Q9UBU6,Q9UBV2,Q8TCT9 10 +Regulation of calcium ion dependent exocytosis 0.598962598887161 1.106940735870553 0.2683195521192405 1.0 0.7305245944306724 5 P16615 1 +Cellular lipid catabolic process 0.3332190309742802 1.1068199097677287 0.2683717984136591 1.0 0.7305245944306724 63 Q99735,P23786,P50897,O43808,A1L0T0,Q9NXE4,O15254,P06280,O95470,Q8NCC3,P17900,P04062,Q13510,P50416,Q8IXJ6,P35610,Q15067,Q8WTV0,Q9BWD1,Q8NCG7,Q8NHP8,Q9NP80,Q05655,P06865,Q8IVS2,Q16836 26 +Polyprenol metabolic process 0.7955892034232785 1.1062319710166648 0.2686261281500339 1.0 0.7305245944306724 2 Q86SQ9 1 +Regulation of neutrophil migration 0.5487846244523663 1.1054568475662487 0.2689616828662484 1.0 0.7305245944306724 7 Q07021,O00429,Q8NHP6 3 +Regulation of neutrophil chemotaxis 0.5487846244523663 1.1054568475662487 0.2689616828662484 1.0 0.7305245944306724 7 Q07021,O00429,Q8NHP6 3 +Positive regulation of fibroblast proliferation 0.5616568291569372 1.099177479330394 0.2716906598626343 1.0 0.7323434410885935 6 Q7Z5K2,Q08211 2 +Regulation of leukocyte migration 0.3824095777868381 1.0958157530696422 0.2731594131578916 1.0 0.7335882432144829 26 P09601,Q99538,Q07021,Q08722,O00429,P04083,P05067 7 +Retrograde transport endosome to golgi 0.3633731048980626 1.09573801906261 0.2731934396019233 1.0 0.7335882432144829 35 O15260,Q13190,Q8NBN3,O43752,Q9UEU0,O95249,O75503 7 +Regulation of mitochondrial fusion 0.5961734347119167 1.0938911378795495 0.2740027259790139 1.0 0.7335882432144829 5 Q9Y6C9 1 +Golgi ribbon formation 0.5605266451884222 1.0935124861093433 0.2741688498618784 1.0 0.7335882432144829 6 Q9H4A6,O43752 2 +Connective tissue development 0.4009915176747608 1.0924952767460376 0.2746154654093753 1.0 0.7340016392523084 22 P43490,Q96HY6,P35610,Q9NX62,P16435,O15173,O75844 7 +Calcium ion regulated exocytosis of neurotransmitter 0.7916392363396904 1.0897295777564835 0.2758322830333977 1.0 0.7369440903574089 2 P16615 1 +Eye photoreceptor cell development 0.8054000658544518 1.08559726408108 0.2776572107538897 1.0 0.7398722087755577 3 Q8NBN7,P54802 2 +Retina morphogenesis in camera type eye 0.8054000658544518 1.08559726408108 0.2776572107538897 1.0 0.7398722087755577 3 Q8NBN7,P54802 2 +Regulation of protein dephosphorylation 0.3795184312881025 1.0850996890237636 0.2778775050596054 1.0 0.7398722087755577 27 P0DP25,Q05655,P04062,P62942 4 +Presynapse organization 0.5580896957028139 1.0812978432354858 0.2795646465158632 1.0 0.7416429343969476 6 P05067 1 +Positive regulation of erad pathway 0.7039818077147553 1.0812753493607627 0.2795746492786479 1.0 0.7416429343969476 4 P51572,Q9UHD9 2 +Regulation of mammary gland epithelial cell proliferation 0.7893350888742284 1.0801168941917532 0.2800901296617482 1.0 0.7420812272322099 2 Q9NQC3 1 +Response to oxygen levels 0.3359896884929333 1.079696320503946 0.2802774329585262 1.0 0.7422680682851637 58 P30519,Q8IXJ6,P52789,P09601,P55786,Q9Y4P3,Q96A26,P07237,P00846,Q8N511,Q96HE7,Q9Y487,Q99808 13 +Response to dexamethasone 0.5576167616946 1.078927475080302 0.2806200596545829 1.0 0.7427509215053782 6 P16435 1 +Negative regulation of response to wounding 0.5432717897734837 1.076877091361985 0.2815351787757842 1.0 0.7430823413069969 7 O75122,Q05655,Q96G23,P55011 4 +Synaptic vesicle membrane organization 0.5570432949613654 1.076053289557566 0.2819034243257774 1.0 0.7430823413069969 6 Q13277,O43760,O95721 3 +Cartilage development 0.4621282240430853 1.0750950183254042 0.2823321896049009 1.0 0.7430823413069969 12 O75844,Q9NX62,Q96HY6,P16435 4 +Glial cell development 0.4108349819163269 1.074720215024344 0.2825000104167288 1.0 0.7430823413069969 19 P08670,Q8IXJ6,Q9NR50,Q92542,P05067 5 +Positive regulation of ubiquitin dependent protein catabolic process 0.3779189379057281 1.07094582499152 0.2841937895085742 1.0 0.7463096314159077 27 P48729,Q8IXJ6,Q96HY6,Q9UHD9,Q9UBS8,P51572,P04062 7 +Myeloid leukocyte mediated immunity 0.4613468817160142 1.070062147264114 0.2845913359234888 1.0 0.7465383950184462 12 P09601 1 +Negative regulation of lipid biosynthetic process 0.5554679267457698 1.06815800335423 0.2854492451418735 1.0 0.748208743127718 6 P05023,O60678,O94905,Q8NF37 4 +Response to mitochondrial depolarisation 0.5402299953718892 1.0611063696679317 0.2886415634528003 1.0 0.7509642968915264 7 O95140,P52789,P04062,O43464 4 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.5402299953718892 1.0611063696679317 0.2886415634528003 1.0 0.7509642968915264 7 O95140,P52789,P04062,O43464 4 +Sequestering of calcium ion 0.4312336084588653 1.0565093483324326 0.290735572160439 1.0 0.7539927256651753 15 P0DP25,P78417,Q96HE7,P62942 4 +Glial cell proliferation 0.6978448505090187 1.0556886807873893 0.2911104702300724 1.0 0.7539927256651753 4 Q96G23 1 +Cdp diacylglycerol metabolic process 0.5388665181811427 1.0540372284362691 0.2918658730370809 1.0 0.7541054833429619 7 Q9NUQ2,O14735,Q86UL3,O95674 4 +Associative learning 0.4410864346366909 1.0472257327499628 0.2949954796722518 1.0 0.7570501176529761 13 O00264,P05067,P50897,Q99538 4 +Phosphatidylcholine acyl chain remodeling 0.6953227931488972 1.0451847815090682 0.2959375757063962 1.0 0.7570501176529761 4 Q96N66,Q8NF37,Q7L5N7 3 +Regulation of cell division 0.3729851185087115 1.0424905742729722 0.2971842932416995 1.0 0.7570501176529761 28 P0DP25,P41208 2 +Nucleoside triphosphate biosynthetic process 0.3603526619975619 1.0420598264198182 0.2973839426246438 1.0 0.7570501176529761 34 Q9UIJ7,P24539,P00846 3 +Vesicle organization 0.3087295788063468 1.0394291089702803 0.2986052119534319 1.0 0.7570501176529761 92 Q86Y82,P49755,Q9Y6B6,P31751,Q14108,O75396,O14617,Q5JRA6,Q9HCU5,Q9NR31,O43633,Q9BTU6,Q8WUM4,Q9UEU0,O00560,Q13190,O15400,P56962,O00743,O14653,Q15363,O15155,P51790,O95721,O95249,Q99523,Q9H4A6,Q9P253,Q8NEB9,O43752,Q13277,Q9H9H4,P04083 33 +Regulation of autophagy of mitochondrion 0.4398695462767739 1.0390111862654812 0.2987995338197511 1.0 0.7570501176529761 13 O43464,P05141,P12235,O00429,P21796,O00165 6 +Phosphatidylethanolamine biosynthetic process 0.7927899296289127 1.036744673811273 0.2998548660751123 1.0 0.7571438105010772 3 Q9UG56 1 +Regulation of membrane permeability 0.415629510079544 1.0334284711192374 0.3014034283481488 1.0 0.7592511138372683 17 P52789,P12235,P45880 3 +Cellular copper ion homeostasis 0.6923583662714256 1.032847703678447 0.3016751754597817 1.0 0.7592511138372683 4 O43819,P05067,O75880 3 +Copper ion homeostasis 0.6923583662714256 1.032847703678447 0.3016751754597817 1.0 0.7592511138372683 4 O43819,P05067,O75880 3 +Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.6921286053555553 1.0318919402303517 0.3021227420664789 1.0 0.7592511138372683 4 O43657 1 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.4713616467517363 1.0316614809575209 0.3022307280259226 1.0 0.7592511138372683 11 Q9NUD5,O43657 2 +Long chain fatty acid transport 0.4333820340405241 1.0315346811096386 0.3022901533929381 1.0 0.7592511138372683 14 P50416,P31751,O43772,P23786,Q9NP80,P11166,P04083,P28288 8 +Regulation of cardiac muscle contraction 0.471207181120793 1.030708498999991 0.3026775379950202 1.0 0.7595019468994663 11 P0DP25,P78417,Q9HD47 3 +Neuron apoptotic process 0.3370461039798862 1.0289957403929213 0.3034816765052153 1.0 0.7610883341356696 50 O76024,Q99720,P09601,Q96A26,P04062,Q9NR28,P50897,Q92542,P05067 9 +Fat cell differentiation 0.3792298952559497 1.0252674670933115 0.3052370018434032 1.0 0.7625137683177602 25 Q9NZ08,Q8IXJ6,Q8N4Q0,O75192,Q96HE7,Q8TDW0 6 +Nls bearing protein import into nucleus 0.5074584987972417 1.022412786650113 0.3065855711654484 1.0 0.7635071184101463 9 Q7Z3B4,P52292,Q8NFH5 3 +Substantia nigra development 0.4134867656055314 1.0176014474348096 0.3088673992095188 1.0 0.7664329627298783 17 P0DP25,P24539,Q8IXJ6 3 +Regulation of exit from mitosis 0.5452603890178892 1.017023433971708 0.3091422816474418 1.0 0.7664329627298783 6 P50748,Q8IXJ6,Q9UJX2 3 +Cholesterol efflux 0.5315611747534971 1.016166954893892 0.3095498895314346 1.0 0.7664329627298783 7 Q86Y82,P61916,Q8WTV0,O15118 4 +Negative regulation of protein serine threonine kinase activity 0.4195053842135015 1.015793953303731 0.3097275160594372 1.0 0.7664329627298783 16 P18031,O95373,Q05655,P04062 4 +Cellular response to lipoprotein particle stimulus 0.78726632363135 1.015419084869536 0.3099060994147922 1.0 0.7664329627298783 3 O15118 1 +Protein retention in golgi apparatus 0.7732060566161958 1.013144138097665 0.3109913183117707 1.0 0.767773053568606 2 Q9H4A6 1 +Embryo implantation 0.4678424274493342 1.009947407312904 0.3125204879835841 1.0 0.7678652952124262 11 Q07021,P35613,Q96GC9 3 +Steroid hormone biosynthetic process 0.5433637635412424 1.007528652529001 0.3136807957673588 1.0 0.7678652952124262 6 Q14849,Q53GQ0 2 +Regulation of endoplasmic reticulum unfolded protein response 0.5259049542794532 1.0074269089322947 0.3137296655272834 1.0 0.7678652952124262 8 Q96HY6,O76024,P57088,O94874,P18031,Q92905 6 +Protein lipid complex assembly 0.6856634652739977 1.0050256729052272 0.3148844879575752 1.0 0.7678652952124262 4 Q6P1A2,P35610 2 +Microglial cell activation 0.7709019091507264 1.0036263279329918 0.3155587594379203 1.0 0.7678652952124262 2 P05067 1 +Pancreas development 0.4505311767086347 1.0003534940054812 0.3171394676978551 1.0 0.7678652952124262 12 Q5T9L3,Q15382,O76024 3 +Dendrite self avoidance 0.7830267226385257 0.9990847522070566 0.3177536368997109 1.0 0.7678652952124262 3 P35613 1 +Proton transporting v type atpase complex assembly 0.7695852534561951 0.9981936695138768 0.3181854555646779 1.0 0.7678652952124262 2 Q8N511 1 +Vacuolar proton transporting v type atpase complex assembly 0.7695852534561951 0.9981936695138768 0.3181854555646779 1.0 0.7678652952124262 2 Q8N511 1 +Regulation of dna binding 0.3760404172039864 0.9978735464327292 0.3183406810271241 1.0 0.7678652952124262 25 P09601,O75844 2 +Positive regulation of synaptic transmission 0.393279121636663 0.9972626574924917 0.3186370344575326 1.0 0.7678652952124262 21 Q99538,Q13277,Q9Y639,Q06787,Q9BPZ3,Q15042,Q92542,P05067,Q14168 9 +Myeloid leukocyte differentiation 0.3677090446247129 0.9951966114091312 0.3196406495560773 1.0 0.7678652952124262 28 Q14739,Q86WC4,P04062,P05067 4 +Neurotransmitter metabolic process 0.6825794898856743 0.9922301250057156 0.3210852802835922 1.0 0.7678652952124262 4 P21964 1 +Neural nucleus development 0.4031596118648308 0.989227333349139 0.3225519280141322 1.0 0.7678652952124262 18 P0DP25,P24539,Q8IXJ6 3 +Negative regulation of mrna catabolic process 0.3839005710568211 0.9880697732121664 0.3231184780515899 1.0 0.7678652952124262 23 O60506,Q13151,Q14103,Q99729,P67809,P98175,P07910,Q08211,Q14011,Q06787,Q92804,P35637 12 +Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 0.7799272972778233 0.9871631647945952 0.3235626563810934 1.0 0.7678652952124262 3 P0DP25 1 +Retinol metabolic process 0.5254302493777799 0.984400021237928 0.324918867629385 1.0 0.7678652952124262 7 Q9HBH5,Q9Y394,Q8NBN7 3 +Sodium ion export across plasma membrane 0.7653061224489806 0.9805691842292852 0.3268052368765031 1.0 0.769608775689905 2 P05023 1 +Photoreceptor cell development 0.6790910783509767 0.9777736441705952 0.3281862889983578 1.0 0.7720029803381059 4 Q8NBN7,P54802 2 +Extracellular vesicle biogenesis 0.4989766817728711 0.97512942464963 0.3294960645381954 1.0 0.7732581551830926 9 O00560,O43633,Q8WUM4 3 +Endocrine pancreas development 0.5365962260134698 0.9736731478212884 0.3302188540510957 1.0 0.7736347351082803 6 Q15382 1 +Regulation of cholesterol metabolic process 0.522253948984298 0.967951272341261 0.3330687059511452 1.0 0.7748214337174185 7 O75477,O94905,Q9H2C2,P16435 4 +Positive regulation of protein localization to cell surface 0.6764122958799789 0.966685461702338 0.3337012970554656 1.0 0.775504732754859 4 Q13277,Q9HD47 2 +Cellular response to leucine 0.761685319289007 0.965695485267805 0.3341965792888102 1.0 0.7758047691598531 2 Q9P2J5 1 +I kappab kinase nf kappab signaling 0.3334685738688626 0.964220766784614 0.3349352549533257 1.0 0.77598433946672 41 Q9P035,Q5T9L3,O43657,P09601,Q86UE4,P62942 6 +Negative regulation of autophagy 0.3763595564083762 0.9616362901187604 0.3362323354780381 1.0 0.77598433946672 24 Q8IXJ6,Q9NQ88,Q07820,P09601,O75396,P10619,P42345,O15118 8 +Response to acidic ph 0.7729216997528741 0.9602831573822184 0.336912724397385 1.0 0.77598433946672 3 Q15907 1 +Cd40 signaling pathway 0.6741483263498049 0.9573236401558066 0.3384039268281316 1.0 0.77677694435522 4 Q99623 1 +Positive regulation of t cell mediated immunity 0.5668006063632433 0.956830069649762 0.3386530322807908 1.0 0.7770375684693198 5 Q9NUQ9,O15400 2 +Secretion 0.3377993145688242 0.9559503976524408 0.339097295228971 1.0 0.7771270973490102 150 O75122,Q15907,Q16850,P11279,P49755,P09601,P27824,Q5JRA6,P50897,Q9HCU5,Q9UBV2,P52789,Q8TBQ9,Q9UEU0,P61026,O00560,Q99808,Q5T9L3,Q9Y5U9,P50416,Q9UNS2,P56962,Q8N5M9,Q4J6C6,P0DP25,P16615,O95721,O00429,O43760,Q9H4A6,Q9P253,Q13505,Q96PC5,Q96KC8,Q8NEB9,Q9BRK5,Q9NP80,Q13277,Q7L0J3,P04083,Q15042,Q7Z6M1,Q16836 43 +Positive regulation of autophagy of mitochondrion 0.5326702474117071 0.9540537755183988 0.3400564226169478 1.0 0.7780412606743413 6 P12235,P21796 2 +Negative regulation of cellular response to insulin stimulus 0.5653423575868612 0.9500520044711078 0.3420858288559802 1.0 0.7809976753622883 5 Q05655 1 +Regulation of striated muscle contraction 0.4425958012197752 0.949191923050656 0.3425230087499238 1.0 0.7810634432788722 12 P16615,P0DP25,P78417,Q9HD47 4 +Glandular epithelial cell development 0.5300942768200743 0.9411908281409586 0.3466070760974618 1.0 0.7865334125628336 6 Q15382,Q86UL3 2 +Regulation of peptidyl threonine phosphorylation 0.4708736745382932 0.937960338469517 0.3482647928160851 1.0 0.7885328585317818 10 P0DP25,P05067 2 +Long chain fatty acyl coa metabolic process 0.4920120480812125 0.9363200814804714 0.3491084118037977 1.0 0.7885328585317818 9 Q9UKU0,Q53GQ0 2 +Regulation of transmembrane transport 0.317139204605763 0.9348506746349176 0.3498652600214396 1.0 0.7885328585317818 65 Q9HD47,P0DP25,P78417,Q96GC9,P21796,O75844,P62942,P05067 8 +Protein o linked glycosylation via serine 0.7660174932482576 0.9338893068952568 0.3503609952654409 1.0 0.7885328585317818 3 Q10472 1 +Potassium ion homeostasis 0.7655581165623975 0.9321368159600004 0.3512658237363411 1.0 0.7885328585317818 3 P05023,P55011 2 +Cellular potassium ion homeostasis 0.7655581165623975 0.9321368159600004 0.3512658237363411 1.0 0.7885328585317818 3 P05023,P55011 2 +Regulation of peptidase activity 0.3065637476462133 0.9314472180267588 0.3516222755927447 1.0 0.7885328585317818 73 P49755,Q9NZJ7,Q99538,Q15392,Q9P0J0,Q9BXK5,P51572,P16435,O14737,P61289,Q9NR28,Q96K76,Q96A26,Q15041,Q92542,P51812,Q96HY6,P04080,Q15418,P05067 20 +Nuclear pore complex assembly 0.4906109855094314 0.928516376708168 0.353139776813701 1.0 0.7889397938714499 9 Q9NQC3,Q9BTX1 2 +Negative regulation of map kinase activity 0.5108593000291539 0.9282032589773992 0.3533021442557376 1.0 0.7889397938714499 8 Q05655,P04062 2 +I kappab phosphorylation 0.6670903439376955 0.9281970131852748 0.3533053834962025 1.0 0.7889397938714499 4 Q96HY6,Q13162 2 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.5102292605317715 0.9248889983196426 0.3550236499090897 1.0 0.7912097892083361 8 P04637,P62942,Q92896 3 +Positive regulation of rig i signaling pathway 0.7511520737326889 0.9226478279478856 0.356190762459549 1.0 0.7918243657507615 2 Q9NUD5 1 +Cell volume homeostasis 0.7625946657886036 0.9208428745195636 0.357132466882833 1.0 0.7918243657507615 3 P54105,P55011 2 +Cell communication by electrical coupling 0.5590091706414599 0.9206560906486712 0.3572300077089827 1.0 0.7918243657507615 5 P0DP25 1 +Regulation of neuronal action potential 0.7504937458854198 0.919968953239598 0.3575889836468313 1.0 0.7919287735398118 2 P04062 1 +Regulation of transmission of nerve impulse 0.7504937458854198 0.919968953239598 0.3575889836468313 1.0 0.7919287735398118 2 P04062 1 +Regulation of retrograde protein transport er to cytosol 0.7501645819618181 0.9186300513211876 0.3582891079823693 1.0 0.7925652670145251 2 P51572 1 +Ribonucleoside triphosphate metabolic process 0.3376100978062432 0.9175587585193608 0.3588499175497517 1.0 0.7925652670145251 38 Q9UIJ7,P24539,P00846 3 +Camera type eye morphogenesis 0.5123713845033293 0.9168321658449292 0.3592305944268519 1.0 0.7925652670145251 7 Q15555,P54802,Q8NBN7 3 +Positive regulation of long term synaptic potentiation 0.6640873493230132 0.9158335203833085 0.3597542192928706 1.0 0.7925652670145251 4 P05067,Q99538 2 +Circulatory system process 0.3144509187344702 0.915131357604773 0.3601226747585593 1.0 0.7925652670145251 66 Q9HD47,Q9HB40,P0DP25,P09601,P78417,P00387,P42892,Q9UIQ6,Q9NZ08,O75844,Q99808 11 +Regulation of cytoplasmic mrna processing body assembly 0.7491770901909054 0.914615503747386 0.3603935167116208 1.0 0.7925652670145251 2 Q9HBH5 1 +Negative regulation of lipase activity 0.7609483042476006 0.9145771944359018 0.3604136355858891 1.0 0.7925652670145251 3 P04083,P16435 2 +Regulation of blood circulation 0.3707686013749595 0.91452738781353 0.360439793548855 1.0 0.7925652670145251 24 Q9HD47,P0DP25,P78417,P16615,P42892,P10253,O75844 7 +Aspartate transmembrane transport 0.6634280372330339 0.9131215709191484 0.3611786065726856 1.0 0.7925652670145251 4 Q8TDW0,Q9UJS0 2 +Phosphatidylglycerol acyl chain remodeling 0.7478604344963744 0.9092678608198492 0.363208751094735 1.0 0.7925652670145251 2 Q8NF37 1 +Positive regulation of fatty acid biosynthetic process 0.7478604344963687 0.9092678608198268 0.363208751094747 1.0 0.7925652670145251 2 P04083 1 +Phosphatidylinositol acyl chain remodeling 0.7478604344963541 0.909267860819766 0.363208751094779 1.0 0.7925652670145251 2 Q96N66 1 +Regulation of spontaneous synaptic transmission 0.7595184129656178 0.9091405414457476 0.3632759449090237 1.0 0.7925652670145251 3 P05067 1 +Spontaneous synaptic transmission 0.7595184129656178 0.9091405414457476 0.3632759449090237 1.0 0.7925652670145251 3 P05067 1 +Positive regulation of blood circulation 0.7590950364123739 0.9075317420210376 0.3641256716666343 1.0 0.7925652670145251 3 P16615 1 +Atp biosynthetic process 0.3854170165640133 0.9056152650285336 0.3651395262259567 1.0 0.7925652670145251 20 P24539,P00846 2 +Sprouting angiogenesis 0.4199286068909699 0.9043651819803116 0.3658017941875897 1.0 0.7925652670145251 13 P09601 1 +Very long chain fatty acid metabolic process 0.4650999312506534 0.9038037613601424 0.36609946692075 1.0 0.7925652670145251 10 Q9NZ01,Q9P035,Q9UKU0,Q15067,P28288 5 +Positive regulation of reproductive process 0.5096427787171494 0.9027381511448428 0.3666648832437165 1.0 0.7925652670145251 7 O14965,Q8IXJ6,Q07021 3 +Energy derivation by oxidation of organic compounds 0.3175206273379776 0.9021110352227284 0.3669978874023931 1.0 0.7925652670145251 120 Q9BSK2,Q9H3K2,P03886,O14949,P24539,O96000,O75964,Q9NZ45,O43676,P14406,Q9UDW1,P04062,P00846,Q7KZN9,P13073,Q13423,Q15070 17 +Copi coated vesicle budding 0.6599566505361307 0.8988579906108207 0.3687283066978173 1.0 0.7925652670145251 4 P49755 1 +Protein deneddylation 0.505228046601152 0.8985946489023662 0.3688686100119283 1.0 0.7925652670145251 8 Q9BT78,Q9UNS2,Q9UBW8,Q99627,Q92905 5 +Histone h3 k36 methylation 0.7452271231073083 0.8985903499709088 0.3688709006740247 1.0 0.7925652670145251 2 O96028 1 +Regulation of receptor mediated endocytosis 0.3768222136102287 0.8964824726216875 0.3699951373015953 1.0 0.7925652670145251 22 P50897,P05067 2 +Regulation of complement activation 0.7561261418530889 0.8962624618237811 0.3701126026606429 1.0 0.7925652670145251 3 Q07021 1 +Regulation of humoral immune response 0.7561261418530889 0.8962624618237811 0.3701126026606429 1.0 0.7925652670145251 3 Q07021 1 +Complement activation 0.7561261418530889 0.8962624618237811 0.3701126026606429 1.0 0.7925652670145251 3 Q07021 1 +Regulation of protein targeting 0.3766295707871619 0.8949199340029538 0.3708298899084439 1.0 0.7925652670145251 22 O43464,Q9UII2,Q9GZY8,P31751,O14737,P27105,Q9Y371,P55786,O95429,O00165 10 +Low density lipoprotein particle clearance 0.4635941232036837 0.8949001773465759 0.3708404519555035 1.0 0.7925652670145251 10 P35610,Q92945,Q8WTV0,P09601 4 +Negative regulation of organic acid transport 0.7439104674127726 0.8932606615538128 0.3717175992716015 1.0 0.7925652670145251 2 O75915 1 +Positive regulation of fatty acid beta oxidation 0.7439104674127726 0.8932606615538128 0.3717175992716015 1.0 0.7925652670145251 2 P50416 1 +Positive regulation of fatty acid oxidation 0.7439104674127726 0.8932606615538128 0.3717175992716015 1.0 0.7925652670145251 2 P50416 1 +Positive regulation of protein containing complex disassembly 0.5077609118690886 0.8930239478630585 0.3718443482285978 1.0 0.7925696436421756 7 Q6ZU35 1 +Ovulation cycle 0.5528010111201935 0.8919136709585959 0.3724392064392323 1.0 0.7929877251824899 5 O95470 1 +Angiogenesis involved in wound healing 0.7546921303918341 0.8908271282198816 0.3730219190860158 1.0 0.7929958147338246 3 P15291,P55011 2 +Embryonic axis specification 0.5196961287328958 0.8893672756583608 0.3738057261034377 1.0 0.7932918848458933 6 P35222,Q9HCM4,Q9UK61,Q15363 4 +Embryonic pattern specification 0.5196961287328958 0.8893672756583608 0.3738057261034377 1.0 0.7932918848458933 6 P35222,Q9HCM4,Q9UK61,Q15363 4 +Cholesterol storage 0.7534375823439002 0.8860763121178409 0.3755764066307412 1.0 0.7937143687205289 3 Q8WTV0 1 +Negative regulation of insulin secretion involved in cellular response to glucose stimulus 0.7419354838709362 0.8852777179844301 0.3760068645638088 1.0 0.7937143687205289 2 Q8N5M9 1 +Negative regulation of protein containing complex assembly 0.3341028847818615 0.8817108095473757 0.3779332139664861 1.0 0.7944264175582545 38 Q9NUQ9,P04062,Q6ZU35,P45880 4 +Constitutive secretory pathway 0.7514855091994548 0.8786921801691475 0.3795681997450058 1.0 0.7945303851997948 3 Q15907 1 +Protein import into peroxisome matrix 0.7510701350016373 0.877122233642954 0.3804202495058351 1.0 0.79485572184718 3 O75381,Q9Y5Y5 2 +Protein import into peroxisome membrane 0.7510701350016349 0.8771222336429443 0.3804202495058404 1.0 0.79485572184718 3 P40855,Q9Y5Y5 2 +Peptidyl proline modification 0.3473352795977285 0.8759363284987505 0.3810646487254381 1.0 0.7949253334557225 32 O75718,Q9BV86,Q9Y680,P07237,O95302,Q96HE7,Q9NWM8,P62942,P13674 9 +Regulation of morphogenesis of a branching structure 0.7505641974863555 0.8752106150841106 0.3814593184919959 1.0 0.7949253334557225 3 Q9NQC3 1 +Phospholipid transport 0.414803350440224 0.8697955486347082 0.3844121445379962 1.0 0.7970178341189229 13 Q14108,Q05655,Q8WTV0,Q96GC9 4 +Antiviral innate immune response 0.5479214294370763 0.8693803844274277 0.3846391084783964 1.0 0.7971197174726729 5 Q9NVI7 1 +Regulation of phospholipid metabolic process 0.4591908851914002 0.8688788890092967 0.3849133776365132 1.0 0.7974281056902471 10 Q99623,Q05655,Q8WTV0,Q8NF37 4 +Positive regulation of ion transmembrane transport 0.3651652536751967 0.8673325160962833 0.3857598455356519 1.0 0.7982975504513614 24 P0DP25,Q96GC9 2 +Synaptic signaling 0.2909135873367255 0.8636888038707838 0.3877588657374602 1.0 0.7982975504513614 84 Q99538,P57105,Q9BPZ3,P50897,O00560,Q99808,P52292,Q4J6C6,P0DP25,P16615,O95721,Q9P253,Q92542,P51812,Q8NCG7,Q13277,Q7L0J3,Q15418,Q9Y639,Q15042,P05067 21 +Cellular response to extracellular stimulus 0.3238303612235317 0.8628693995429848 0.388209276910423 1.0 0.7982975504513614 44 P09601,Q9H773,Q8NEB9,P04062,P21964 5 +Ubiquitin dependent erad pathway 0.339551752425681 0.8625943774128753 0.3883605228209044 1.0 0.7982975504513614 35 Q9BUN8,Q96A33,O76024,Q9UHD9,Q92575,P51572,P27824,Q9UBU6,Q9UBV2 9 +Regulation of body fluid levels 0.3236169073723599 0.8605474669575303 0.3894873297842758 1.0 0.7997799406907121 44 Q13505,P38435,P52789,P61225,Q05655,P04062,Q9BWH2,Q9UIJ7,Q99808 9 +Insulin secretion involved in cellular response to glucose stimulus 0.4778711787519653 0.8576479712643337 0.3910868775343332 1.0 0.801544777516505 9 Q15907 1 +Negative regulation of cold induced thermogenesis 0.5008148527153475 0.8572184873177905 0.3913241471557498 1.0 0.801544777516505 7 Q9UIQ6 1 +Polyol biosynthetic process 0.4430411409840384 0.8570081696112 0.3914403696367576 1.0 0.801544777516505 11 P00374,P04062,Q13510 3 +Insulin processing 0.7346938775510155 0.8561306612390908 0.3919255106284689 1.0 0.8017463688749044 2 Q96HE7 1 +Phosphatidylcholine metabolic process 0.3968663472546618 0.8525179524746048 0.3939266792707592 1.0 0.8021309186253683 16 Q96N66,Q8WTV0,Q8NF37,Q9NP80 4 +Feeding behavior 0.4998823950595374 0.8524185550619889 0.3939818252407101 1.0 0.8021309186253683 7 P05067 1 +Glycerol ether metabolic process 0.511466803002247 0.8484933922214823 0.3961632508811401 1.0 0.8042039875496396 6 O00116,Q6IAN0,Q7L5N7,P49327 4 +Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.7314022383146818 0.8429492735142154 0.3992568144029276 1.0 0.8049363994586524 2 O43464 1 +Protein quality control for misfolded or incompletely synthesized proteins 0.4256330042456057 0.8399699446365015 0.4009252384039001 1.0 0.8049363994586524 12 Q9BUN8,Q16740,Q96E52 3 +Glycosyl compound metabolic process 0.3516593982553885 0.838173284892976 0.4019333887013196 1.0 0.8049363994586524 27 P06280,O60725,Q13126,P04062,P08236 5 +Cytoplasmic pattern recognition receptor signaling pathway 0.4047486499554479 0.83414613325848 0.4041986412429796 1.0 0.8081429895377096 14 Q9NUD5,O43657 2 +Cell adhesion molecule production 0.6431603695422617 0.8302492094601344 0.4063978979502569 1.0 0.8108777519498972 4 Q9H4A6,Q5KU26 2 +Negative regulation of hormone metabolic process 0.7274522712310727 0.8271900425968061 0.4081293545647462 1.0 0.8117539225111493 2 P05023 1 +Intraciliary transport involved in cilium assembly 0.72712310730744 0.825879727951058 0.4088723212765899 1.0 0.8117539225111493 2 Q15154 1 +T cell differentiation in thymus 0.4720610925244698 0.8254044304039366 0.4091420204717173 1.0 0.8117539225111493 9 O96005 1 +Azole transmembrane transport 0.7264647794601405 0.8232604858184943 0.4103598789635319 1.0 0.8117539225111493 2 Q9HC21 1 +Nervous system process 0.2986319347564403 0.8228887528252039 0.4105712591973223 1.0 0.8117539225111493 99 Q99538,Q14108,P10253,Q9BPZ3,P50897,O14773,Q14168,Q8IZL8,Q9H0U3,Q9H6K4,P17900,P62072,O00264,P04062,P53634,O75844,Q99808,Q99797,O43924,O76024,O60313,Q15555,P42345,O75569,Q92542,P78417,P53611,O75915,Q9Y5J9,Q9Y639,P50542,Q06787,Q15042,P05067 34 +Posttranslational protein targeting to membrane translocation 0.6410095337207969 0.8215178158078753 0.4113513803572801 1.0 0.8117539225111493 4 Q99442 1 +Protein processing involved in protein targeting to mitochondrion 0.7362631885979144 0.8214753447595222 0.411375562221993 1.0 0.8117539225111493 3 Q10713 1 +Regulation of defense response 0.2872345572186196 0.8206350109102785 0.4118541990335986 1.0 0.8117539225111493 83 O43657,P11279,Q99735,Q7Z739,Q9Y5A9,Q07021,P18031,Q9BXW9,P04439,Q08722,P04062,P53634,O75844,Q8IXJ6,Q96KB5,Q8IZ81,Q9NUD5,P28070,Q9NZ08,P23246,Q08211,Q8NCG7,Q05655,P04083,Q8WXF1,P05067 26 +Neurofilament cytoskeleton organization 0.7251481237656359 0.8180275944472483 0.4133414308231873 1.0 0.813136652461439 2 Q16352 1 +Regulation of anion transmembrane transport 0.5366029247041377 0.8173437066170989 0.4137320361447878 1.0 0.813136652461439 5 Q15041,O75915 2 +Signaling receptor ligand precursor processing 0.7349357918998881 0.8165188736573796 0.4142034333983195 1.0 0.813136652461439 3 P42892,Q96HE7 2 +Alditol phosphate metabolic process 0.7342763360982769 0.8140585672538879 0.4156114001032489 1.0 0.8143113622244915 3 Q9NPH0 1 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.3248223201302179 0.8132338807495131 0.4160839776569502 1.0 0.8146685091375733 39 Q6ZXV5,P48729,Q8IXJ6,O14965,Q96HY6,Q9UHD9,Q9UBS8,P46379,P51572,Q9Y5A7,P04062,P53634 12 +Extracellular exosome assembly 0.6372745123070425 0.8063879067260133 0.4200192176882678 1.0 0.8186575123050076 4 O00560 1 +Protein localization to golgi apparatus 0.4874604020594583 0.8054683767004909 0.4205494478861626 1.0 0.81918856597133 8 P49755,Q9H4A6,P40616 3 +Negative regulation of protein secretion 0.4680886364865057 0.803396392504455 0.4217456594712674 1.0 0.8198429140868885 9 Q16836,Q8N5M9 2 +Regulation of lipid biosynthetic process 0.3575523216012207 0.8032950299630442 0.4218042299087889 1.0 0.8198429140868885 24 Q6P1A2,P11802,O60678,P16435,P05023,O75477,Q05655,Q92604,O94905,Q13510,P42345,Q8WTV0,Q8NF37,P04083 14 +Vesicle docking involved in exocytosis 0.4679681686539317 0.8027295150421743 0.4221310895896235 1.0 0.8198429140868885 9 Q9UEU0,Q9P253,P61026 3 +Vesicle localization 0.3094888868131119 0.8024818889413942 0.4222742607213867 1.0 0.8198429140868885 62 Q15907,O75122,Q92845,Q13561,P49755,Q9Y6B6,Q96A57,O14617,Q9HCU5,Q9NR31,Q14849,O43633,Q8WUM4,O00560,Q92905,O95772,O00743,Q15363,O95721,Q9Y2T2,O15027 21 +Aromatic amino acid transport 0.7208689927583948 0.8010733152210281 0.4230892034847762 1.0 0.8198643223625723 2 Q8N697 1 +Negative regulation of inflammatory response 0.4338832683426463 0.8007176607070551 0.4232951160519342 1.0 0.8200133366736038 11 P28070,P04062 2 +Regulation of pattern recognition receptor signaling pathway 0.3838058518219868 0.7985342152507325 0.4245605459047823 1.0 0.8208146223381564 17 O43657,Q9NQC3 2 +Cellular modified amino acid catabolic process 0.5009413550865826 0.7964496548816229 0.4257707268223405 1.0 0.8218034435720609 6 Q9UHG3 1 +Regulation of protein tyrosine kinase activity 0.4184402196198509 0.7937966264431533 0.4273138369288345 1.0 0.8221125146870794 12 P61225,P18031,P05067 3 +Regulation of protein autophosphorylation 0.4660400308050708 0.7920604327057488 0.4283254397090221 1.0 0.8221125146870794 9 P0DP25 1 +Phosphatidylglycerol biosynthetic process 0.7283485454484435 0.7920070991607896 0.4283565368348767 1.0 0.8221125146870794 3 Q8WUK0 1 +Columnar cuboidal epithelial cell development 0.4846870499442973 0.7909873708226669 0.4289513612315252 1.0 0.8221125146870794 8 Q15382,Q9NQ88,Q86UL3 3 +Interleukin 6 production 0.3984641202793937 0.7909719582109732 0.4289603553453862 1.0 0.8221125146870794 14 Q08722,P05067 2 +Plasma lipoprotein particle clearance 0.4320098458609969 0.7892248396874927 0.4299806064034976 1.0 0.8221125146870794 11 P35610,Q92945,Q8WTV0,P09601 4 +Pattern recognition receptor signaling pathway 0.3460190284698321 0.7882454354138935 0.4305531572672096 1.0 0.8221125146870794 27 Q9NUD5,O43657,Q9NQC3 3 +Superoxide metabolic process 0.4872985579129845 0.7878319761767189 0.4307949945399674 1.0 0.8221125146870794 7 P00374 1 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.6320816864295289 0.7854248604886217 0.4322045094952917 1.0 0.8221125146870794 4 O95373,P24468,O00410 3 +Regulation of exosomal secretion 0.4832025099461847 0.7832434699893959 0.4334841523852981 1.0 0.8221125146870794 8 O00560,Q8WUM4 2 +Positive regulation of exosomal secretion 0.4832025099461847 0.7832434699893959 0.4334841523852981 1.0 0.8221125146870794 8 O00560,Q8WUM4 2 +Chondroitin sulfate proteoglycan metabolic process 0.631471348155537 0.7829667225836318 0.4336466538552876 1.0 0.8221125146870794 4 Q9NX62,Q96L58 2 +Collagen biosynthetic process 0.5286595690325664 0.7810493640861192 0.434773461739701 1.0 0.8221125146870794 5 Q92791 1 +Response to corticosterone 0.7253868949621168 0.7810343605175366 0.434782285812485 1.0 0.8221125146870794 3 P20020,P0DP25 2 +Regulation of protein folding 0.6305972746529869 0.779448559943484 0.4357155281349207 1.0 0.8226270234024686 4 O14737 1 +Regulation of protein secretion 0.3161910063520459 0.7791280075570168 0.4359043132189293 1.0 0.8226270234024686 42 Q16850,Q9Y5U9,Q5T9L3,P50416,Q8N5M9,P49755,Q96KC8,Q8NEB9,Q8N183,O00429,P40939,Q16836,Q9H4A6,Q8NE86,P55011 15 +Skeletal muscle contraction 0.7236169362016839 0.7744915064212954 0.4386401890328422 1.0 0.8255839625385684 3 P78417 1 +Cerebellar cortex development 0.4152172993989578 0.7731498457500843 0.4394337043399547 1.0 0.8257790029018133 12 P04062,O14949 2 +Regulation of dephosphorylation 0.3342838798555864 0.7709109171321348 0.4407597357296247 1.0 0.8257790029018133 33 P0DP25,Q05655,P04062,P62942 4 +Regulation of t cell mediated immunity 0.4954888022401851 0.7696142436096699 0.4415287533116083 1.0 0.8257790029018133 6 Q9NUQ9,O15400 2 +Temperature homeostasis 0.3534551826102974 0.7688971713799752 0.4419543567603083 1.0 0.8257790029018133 24 Q96E52,Q16836,P23786,Q9UIQ6 4 +Cellular response to heat 0.3450771994401093 0.7687807715890959 0.4420234656038113 1.0 0.8257790029018133 26 P09601 1 +Transepithelial chloride transport 0.7217648995719292 0.7676573168603646 0.44269080060588 1.0 0.8257790029018133 3 Q86WC4,P55011 2 +Organelle disassembly 0.3148395943496664 0.767539392005042 0.4427608816701185 1.0 0.8257790029018133 46 Q96HY6,P05141,P52789,P12235,Q9Y6I9,P04062,Q9BWH2,P21796,Q13190 9 +Anatomical structure maturation 0.3436593694668955 0.767386954272038 0.442851482646551 1.0 0.8257790029018133 27 Q8IXJ6,O14965,Q15125,Q9NZJ7,Q9Y5A9,P04062,Q15645,P05067,O75503 9 +3 utr mediated mrna destabilization 0.4950176834120083 0.7673000783938451 0.4429031218439554 1.0 0.8257790029018133 6 Q14103,Q9HCE1 2 +Viral protein processing 0.4831081332116876 0.7664166733737836 0.4434284150169252 1.0 0.8257790029018133 7 Q10472,P27824 2 +Pyridine containing compound catabolic process 0.7214116584308381 0.7663552451198913 0.4434649549170797 1.0 0.8257790029018133 3 Q13126 1 +Intraciliary transport 0.5252008111043327 0.7653122228014755 0.4440856474403074 1.0 0.8260436883399578 5 Q15154,O43805 2 +Positive regulation of er associated ubiquitin dependent protein catabolic process 0.7207890686839702 0.7640614546169524 0.4448306210755353 1.0 0.8260436883399578 3 Q9UHD9 1 +Response to testosterone 0.4794917194160644 0.7639115635198979 0.4449199459469803 1.0 0.8260436883399578 8 Q13126,P04062 2 +Regulation of atp metabolic process 0.3442105668285942 0.7612126358691201 0.4465300721616558 1.0 0.8260436883399578 26 Q9BSK2,P14406 2 +Cellular response to hyperoxia 0.7106649111257419 0.7609864448238437 0.4466651636670504 1.0 0.8260436883399578 2 P49327 1 +Autophagic cell death 0.7106649111257418 0.7609864448238437 0.4466651636670504 1.0 0.8260436883399578 2 Q9Y371 1 +Negative regulation of ire1 mediated unfolded protein response 0.7103357472020825 0.7597017570526527 0.4474328782525534 1.0 0.8260436883399578 2 Q96HY6 1 +Negative regulation of alcohol biosynthetic process 0.7100065832784739 0.7584176153194366 0.4482010156936677 1.0 0.8264478258627653 2 O94905 1 +Negative regulation of cholesterol metabolic process 0.7100065832784739 0.7584176153194366 0.4482010156936677 1.0 0.8264478258627653 2 O94905 1 +Negative regulation of endoplasmic reticulum unfolded protein response 0.4930947835136268 0.7578625126354208 0.4485332942281497 1.0 0.8266693727342211 6 Q96HY6,O76024 2 +Peptidyl asparagine modification 0.4401600615266237 0.7568019789950776 0.4491685070255724 1.0 0.8266693727342211 10 P04844,P46977 2 +Cellular response to estradiol stimulus 0.7188014487981542 0.756748174034697 0.4492007474167991 1.0 0.8266693727342211 3 O95831,Q14103 2 +Axis specification 0.4401421151915485 0.7566966966921354 0.44923159430837 1.0 0.8266693727342211 10 Q5T9L3,Q15363 2 +Response to thyroglobulin triiodothyronine 0.7093482554311734 0.7558509768750802 0.4497385490313088 1.0 0.8271233268642936 2 P16278 1 +Positive regulation of mitochondrial membrane potential 0.6238729219780177 0.7524714087894824 0.4517676175008716 1.0 0.8287749139681069 4 Q9UJZ1,Q8IWA4 2 +Maintenance of protein location in cell 0.3688445621239539 0.7519387348362032 0.4520879027250171 1.0 0.8287749139681069 19 O15258,O43731,P52789,P24390 4 +Regulation of plasma lipoprotein particle levels 0.3970357189660529 0.7503657012704202 0.4530344822778704 1.0 0.8298233917458631 13 P35610,Q92945,Q8WTV0,P09601 4 +Entry into host 0.3403396147491616 0.7498992520688633 0.4533153849926878 1.0 0.8299515010501518 28 P11279,Q14108,P35613,P07237,Q9P253,Q8WTV0,O15118 7 +Vacuolar transport 0.3125443996680287 0.7493295584572942 0.4536585963487722 1.0 0.8302487873287637 49 P11279,Q96L92,P07602,Q9NZJ7,Q14108,Q9UEU0,Q9Y2T2,O15118 8 +Macrophage differentiation 0.6227540647333341 0.7479984817153156 0.454461073338648 1.0 0.8309995921002435 4 P05067 1 +Cardiac muscle contraction 0.3767611873344663 0.7467920567786652 0.4551890910987772 1.0 0.8312098451264622 17 Q9HD47,P0DP25,P78417,P16615,P05023,P10253 6 +Negative regulation of transport 0.2915022922641592 0.746641307009561 0.4552801072566126 1.0 0.8312098451264622 74 Q8N5M9,P09601,P0DP25,P78417,Q08722,P21796,O00560,Q16836,P62942,P05067 10 +Early endosome to golgi transport 0.478849815598131 0.7447102005586915 0.4564469312739476 1.0 0.8315209788412758 7 Q13190 1 +Regulation of stem cell differentiation 0.3817113340580854 0.7436860819784101 0.4570664115060214 1.0 0.8317503340720942 16 Q9Y6C9,Q9NX40,Q8WX92 3 +Negative regulation of neuron apoptotic process 0.3420686677348729 0.7425214271091148 0.4577714744630787 1.0 0.8317503340720942 26 P09601,P50897,P04062,O76024 4 +Negative regulation of cell growth 0.3577804216512279 0.7424064916069352 0.4578410876072156 1.0 0.8317503340720942 22 P50897,Q9NQC3 2 +Inflammatory response 0.3006593455017193 0.7400843753699891 0.4592487987617919 1.0 0.8317503340720942 66 P09601,P28070,Q9BQE5,Q8NCG7,Q08722,P04062,P05067,Q8IV08 8 +Protein o linked glycosylation 0.3909931721671881 0.7398017292085614 0.4594203096217388 1.0 0.8317503340720942 14 Q6ZXV5,O43505,Q10471,Q10472 4 +Mitochondrial outer membrane permeabilization 0.474719032824795 0.7391046832778472 0.4598434332587353 1.0 0.8318983230127595 8 P45880 1 +Lactation 0.4229405484600184 0.7337282080912929 0.4631144029905871 1.0 0.8345775858826685 11 Q13505,P52789 2 +Fucose metabolic process 0.7120001792439337 0.7318382628861486 0.4642672917760881 1.0 0.8348543787378784 3 Q9BTY2 1 +Cellular response to unfolded protein 0.3368066882579559 0.7310233351170106 0.4647648997719313 1.0 0.8348543787378784 29 Q9BUN8,Q96HY6,O76024,Q7Z2K6,P57088,P48723,Q9Y4P3,P18031,Q96HE7 9 +Mitochondrial gene expression 0.3094419049529281 0.7305779660414577 0.4650369746103628 1.0 0.8348543787378784 53 Q9BSK2,Q9Y2R0,O60783,O15091,Q9BW92,Q567V2 6 +Leukocyte migration 0.3112851382367426 0.7301954778062457 0.4652707063761756 1.0 0.8348543787378784 47 P05067,Q8N5M9,P09601,Q99538,Q07021,P35613,Q08722,P04062,P15291,Q9BW27,O00429,Q9H4A6,Q5JRA6,P55011,P04083 15 +Regulation of endocytosis 0.3114311118329039 0.7288169257255201 0.4661136566520856 1.0 0.8359532736119233 45 P57105,P0DP25,P50897,P05067 4 +Negative regulation of steroid metabolic process 0.7102403687849784 0.725422843729153 0.4681926630442112 1.0 0.8376448004648234 3 P05023,O94905 2 +Positive regulation of torc1 signaling 0.6168461209420206 0.7244588824595135 0.4687840615723107 1.0 0.8376448004648234 4 Q9Y4R8,Q9P2J5 2 +Regulation of dna templated transcription in response to stress 0.3929953499954478 0.723343938870746 0.4694686043147649 1.0 0.8376448004648234 13 P09601,P51812,Q8IXJ6 3 +Photoreceptor cell maintenance 0.709581824168587 0.7230253703837078 0.4696642975104794 1.0 0.8376448004648234 3 Q15555,P51790 2 +Regulation of reproductive process 0.3678621452511283 0.7226465501916156 0.4698970613550728 1.0 0.8376448004648234 18 O14965,Q8IXJ6,Q7Z739,Q9Y5A9,Q13162,Q07021,Q15645,P15291 8 +Positive regulation of epithelial cell proliferation 0.3552494483886175 0.72201963151962 0.4702824078494485 1.0 0.8376448004648234 22 P09601 1 +Mitochondrial translation 0.3107821821103386 0.7217662517973282 0.4704382016246131 1.0 0.8376448004648234 41 O60783,Q9Y2R0,Q9BW92,Q567V2 4 +Cellular response to external stimulus 0.3098086322509913 0.7186871298811117 0.4723337149355451 1.0 0.8380624373956013 49 P09601,Q9H773,Q8NEB9,P04062,P21964 5 +Neuron death 0.29570636652646 0.7183070645212984 0.4725679752243639 1.0 0.8380624373956013 69 O76024,Q99720,P09601,Q96A26,P04062,Q15392,Q9NR28,P50897,Q92542,P05067 10 +Digestive system process 0.3922404938091481 0.7183029135178972 0.4725705341249486 1.0 0.8380624373956013 13 Q6ZU35 1 +Cellular response to starvation 0.3305539549791735 0.7181593352956994 0.47265904811879 1.0 0.8380624373956013 32 Q8NEB9,P04062,P21964 3 +Regulation of phospholipid catabolic process 0.7081125031222426 0.7176826991139739 0.4729529531897813 1.0 0.8380624373956013 3 Q8WTV0 1 +Fatty acid transport 0.3667883197035639 0.7145934633151227 0.4748602850316534 1.0 0.8396062781959199 18 P50416,P31751,O43772,P23786,Q9NP80,P11166,P04083,P28288,O43808 9 +Organ growth 0.3636435535031608 0.7122276460515277 0.4763238200450992 1.0 0.8409866285863123 19 P07602,Q9NZJ7,O75844,P16435 4 +Multivesicular body organization 0.3866490416391247 0.7101463045167388 0.4776134144520283 1.0 0.8418499340701864 14 Q9BRG1,Q9HD42,Q9NZZ3,O43633,Q9H444,Q92783,O14964,Q8WUM4,Q9NP79,P53990,Q8WUX9,Q9H9H4,Q99816 13 +Inflammatory cell apoptotic process 0.7053258661091022 0.7075750585507149 0.4792091860352419 1.0 0.8422538359638093 3 O75844 1 +Piecemeal microautophagy of the nucleus 0.6968400263331151 0.7075198387268281 0.4792434885603045 1.0 0.8422538359638093 2 O95352 1 +Purine nucleoside metabolic process 0.4503645624134388 0.7057063617331584 0.4803707639205918 1.0 0.8429257563354444 9 O60725 1 +Regulation of heart contraction 0.3531242197162663 0.7049256802751642 0.4808564878870083 1.0 0.8429257563354444 22 P0DP25,O75844,Q9HD47 3 +Homophilic cell adhesion via plasma membrane adhesion molecules 0.467946011259323 0.7040258125245945 0.481416698832088 1.0 0.8429257563354444 8 P19022,P35613,Q9Y639,Q14126,Q9H3S7 5 +Lipid droplet organization 0.44998281105965 0.7036134102815697 0.4816735577077575 1.0 0.8429257563354444 9 Q14534,Q15042,Q96CS3,O95674 4 +Natural killer cell activation 0.4705195452622598 0.7024316277754663 0.4824100269425393 1.0 0.8429257563354444 7 P46379,P11279,Q96L92 3 +Regulation of cardiac muscle cell action potential involved in regulation of contraction 0.6112290942479552 0.7022080066200759 0.4825494531430876 1.0 0.8429257563354444 4 Q9HD47 1 +Alpha beta t cell proliferation 0.6951942067149395 0.7012248933076398 0.4831626769831765 1.0 0.8429257563354444 2 P04439 1 +Positive regulation of receptor catabolic process 0.6951942067149355 0.7012248933076242 0.4831626769831862 1.0 0.8429257563354444 2 P18031 1 +Perk mediated unfolded protein response 0.5103459570781689 0.6982542776981635 0.4850181875997745 1.0 0.8429257563354444 5 P18031,P57088 2 +Fatty acid alpha oxidation 0.702543144760855 0.6975150110373897 0.4854805485405422 1.0 0.8429257563354444 3 A1L0T0 1 +Regulation of acyl coa biosynthetic process 0.6942067149440434 0.697455452084912 0.4855178089905698 1.0 0.8429257563354444 2 Q15118 1 +Hypoxia inducible factor 1alpha signaling pathway 0.6942067149440434 0.697455452084912 0.4855178089905698 1.0 0.8429257563354444 2 Q15118 1 +Nucleoside triphosphate metabolic process 0.3080864781143665 0.6968686040117745 0.4858850275352622 1.0 0.8431027122615687 48 Q9UIJ7,P24539,O75964,P00846 4 +Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules 0.7022507041904906 0.6964597582190466 0.4861409504291085 1.0 0.8431741258105265 3 P98194 1 +Intracellular protein transport 0.358841927350863 0.6952963786730142 0.486869583246535 1.0 0.8438102910229716 312 Q86Y82,P43307,Q9NS69,Q8N4H5,Q9UGP8,Q99595,P49755,O60830,O60725,P18031,P50402,P57105,Q9HCU5,Q53FT3,Q9Y282,P62072,P51572,Q9P2W9,O43615,Q9Y3B3,Q9BW27,O14925,Q15070,Q99797,Q15005,Q5T9L3,Q9Y584,Q9HD47,Q3ZCQ8,O43592,Q8NFH5,Q15363,P10619,Q15041,Q9UHB9,Q9Y3A6,O43752,Q9Y371,Q96P70,Q8TCT9,Q15629,Q9BUN8,O43464,Q99623,Q15904,Q9Y6B6,Q15154,Q8N8Q8,P40616,O00165,Q14168,Q9HAV7,Q8TEX9,P46379,Q96RL7,O14737,P27105,Q15388,P53680,O00560,O95429,Q92544,Q5JRX3,Q9Y2T2,Q9Y5M8,P40855,Q969Q5,Q9Y5J9,O95373,Q05655,O60220,Q14108,Q9C0E2,Q10713,Q9NR31,Q9P0J0,O75381,Q13190,Q96L92,Q13277,P55786,Q7Z4Q2,O15397,Q9UBV2,Q9GZY8,Q92973,Q53H12,Q9UEU0,Q9Y512,Q8N1F7,P52292,O15400,O15260,P56962,Q7Z3B4,Q9P253,O96008,Q99442,Q9Y5Y5,Q9H0U4 100 +Negative regulation of mitophagy 0.6935483870967756 0.6949456580578559 0.4870893577349406 1.0 0.8438102910229716 2 Q9NQ88 1 +Negative regulation of autophagy of mitochondrion 0.6935483870967756 0.6949456580578559 0.4870893577349406 1.0 0.8438102910229716 2 Q9NQ88 1 +Anaphase promoting complex dependent catabolic process 0.4482391648384624 0.6940609287871277 0.4876439997610315 1.0 0.8444817730774132 9 Q9UJX2 1 +Branching involved in labyrinthine layer morphogenesis 0.6932192231731396 0.6936917166727458 0.4878755617904753 1.0 0.8444817730774132 2 Q15363 1 +Labyrinthine layer morphogenesis 0.6932192231731396 0.6936917166727458 0.4878755617904753 1.0 0.8444817730774132 2 Q15363 1 +Negative regulation of defense response 0.3325434014791236 0.6925693532672356 0.488579848531131 1.0 0.8447806086136749 29 O43657,Q8IXJ6,Q96KB5,P28070,Q9Y5A9,Q07021,P04439,Q05655,P04062 9 +Regulation of mitochondrial membrane permeability involved in apoptotic process 0.4477370571578482 0.6913123493645826 0.4893692727599832 1.0 0.8454212280398428 9 P45880 1 +Srp dependent cotranslational protein targeting to membrane 0.4287338426618268 0.6899867150852437 0.49020254178243 1.0 0.8458534304777954 10 Q9UHB9 1 +Cd4 positive alpha beta t cell activation 0.5082084231841475 0.6886838602500884 0.4910222350477329 1.0 0.8464706606898266 5 Q9UJZ1,P04083 2 +Heart process 0.3346284197584325 0.687785763323163 0.4915877026765853 1.0 0.8469860228279686 27 Q9HD47,P0DP25,P78417,P16615,P05023,P10253,O00429,O75844 8 +Calcium ion export across plasma membrane 0.6987158379980056 0.683734726862697 0.4941426905892716 1.0 0.8485584831472498 3 P20020,P0DP25 2 +Dna templated transcription termination 0.4777537660921426 0.6830762514073951 0.4945586610930115 1.0 0.8485584831472498 6 O75844,Q08211 2 +Negative regulation of protein tyrosine kinase activity 0.5067545304777458 0.6821867420775661 0.495120876883746 1.0 0.8485584831472498 5 O95684,Q9BRG1,P63244,Q9UNH7 4 +Iron ion transmembrane transport 0.6979904923622817 0.6811306018750565 0.4957888551068863 1.0 0.8485584831472498 3 Q8N4V1 1 +Hypothalamus development 0.6052310331564074 0.6785971194140681 0.4973931685312784 1.0 0.8498470374152705 4 Q15042,O14949 2 +Organophosphate catabolic process 0.3164247634561534 0.6780451639704672 0.4977430576077108 1.0 0.8498494775146057 37 Q9NXE4,Q9BQG2,Q8NCC3,Q9H773,Q9NX62,Q8NHP8,Q9NP80,Q05655,Q10713,Q8WTV0 10 +Membrane raft organization 0.445191695831219 0.6773944996637006 0.4981556872348425 1.0 0.8500073954535997 9 P50897 1 +Synaptonemal complex organization 0.476525786486685 0.6771336228678423 0.4983211777016576 1.0 0.8500615688329941 6 Q92791,Q15645 2 +Bone remodeling 0.4448634494563671 0.675601628799988 0.4992936071146312 1.0 0.8512634567651813 9 O14773 1 +Positive regulation of actin nucleation 0.6882817643186319 0.6749603983488026 0.4997009255699236 1.0 0.8515010946172747 2 Q9Y2A7 1 +Positive regulation of arp2 3 complex mediated actin nucleation 0.6882817643186319 0.6749603983488026 0.4997009255699236 1.0 0.8515010946172747 2 Q9Y2A7 1 +Cellular response to glucose starvation 0.3992726473786477 0.6715460592053384 0.5018727278903428 1.0 0.853784398787079 12 Q8NEB9 1 +Mitochondrial electron transport nadh to ubiquinone 0.3521569760416434 0.6707201599463989 0.5023988175268821 1.0 0.8539952858384116 21 O75306,P03886,O96000,O75438,O43676 5 +Ventricular cardiac muscle tissue development 0.4747865833050892 0.6687293179348301 0.5036681620122274 1.0 0.8541180400803079 6 O75844 1 +Regulation of sulfur metabolic process 0.694435297991431 0.6684021998678898 0.5038768916310563 1.0 0.8541180400803079 3 Q15118,O75027 2 +Prolactin secretion 0.6863067807767972 0.6675095922672014 0.5044466846423552 1.0 0.8547755605403385 2 P04083 1 +Positive regulation of intracellular protein transport 0.3053720228499575 0.6648815856171185 0.5061262345359401 1.0 0.8560240411682903 47 O43464,Q9GZY8,Q9Y282,Q9Y6B6,P51572,Q15154,Q9C0E2,O14737,P27105,P50402,Q05655,Q9Y371,P55786,Q9NR31 14 +Digestion 0.3797771105784113 0.663418788033882 0.507062376275643 1.0 0.8562086417858756 14 Q6ZU35 1 +Regulation of tube size 0.3976935857663793 0.6615449824942916 0.5082628771343671 1.0 0.8566714034848872 12 Q9HB40 1 +Golgi to vacuole transport 0.4596885760660735 0.6614897602980535 0.508298279229721 1.0 0.8566714034848872 8 Q99523,Q9UEU0,P11279 3 +Response to leucine 0.6008198368208627 0.6613374488396567 0.5083959304507544 1.0 0.8566714034848872 4 Q8NEB9,Q9P2J5 2 +Negative regulation of epithelial cell apoptotic process 0.4718859099733389 0.6547456759452058 0.5126315118890341 1.0 0.8591208099799411 6 P09601 1 +Fat soluble vitamin metabolic process 0.4583145477356728 0.6544394429539696 0.5128287297788447 1.0 0.8591208099799411 8 Q8N0U8,P04062 2 +Pyrimidine nucleotide metabolic process 0.3555448574101618 0.6506788561588931 0.5152538148264165 1.0 0.8591208099799411 19 Q9UIJ7 1 +Cognition 0.3178301695332015 0.6503873669049304 0.5154420355096134 1.0 0.8591208099799411 35 P17900,O00264,Q9BPZ3,P50897,Q92542,P05067 6 +Positive regulation of ion transport 0.3178127300476897 0.6502179175285142 0.515551468904841 1.0 0.8591208099799411 35 O76024,P20020,P0DP25,P54709,P78417,Q96GC9,P08183,Q15041,Q15042,Q9P246,P55011 11 +L glutamate import across plasma membrane 0.6891937312527894 0.6497465974362614 0.5158559191389669 1.0 0.8591208099799411 3 Q15041 1 +Regulation of l glutamate import across plasma membrane 0.6891937312527894 0.6497465974362614 0.5158559191389669 1.0 0.8591208099799411 3 Q15041 1 +Regulation of amino acid transmembrane transport 0.6891937312527894 0.6497465974362614 0.5158559191389669 1.0 0.8591208099799411 3 Q15041 1 +Vasoconstriction 0.4994328083941768 0.6496287563075025 0.5159320534445304 1.0 0.8591208099799411 5 P42892 1 +Receptor clustering 0.4090418307164192 0.649275019771447 0.51616062907779 1.0 0.8592763117911036 11 P57105 1 +Very low density lipoprotein particle assembly 0.6888376687520523 0.6484842155388122 0.5166718167036943 1.0 0.8595302790520045 3 Q6P1A2,P35610 2 +Regulation of lipoprotein metabolic process 0.5968600951673525 0.6459238569636353 0.5183286684668558 1.0 0.8612246467182614 4 Q15042,P04062 2 +Regulation of protein lipidation 0.5968600951673525 0.6459238569636353 0.5183286684668558 1.0 0.8612246467182614 4 Q15042,P04062 2 +T cell differentiation 0.3422405717005441 0.645114302864163 0.5188531156858951 1.0 0.8612246467182614 23 O96005,P04062,P24390 3 +Regulation of glucocorticoid metabolic process 0.679723502304129 0.6428525805980845 0.5203197611174879 1.0 0.8612246467182614 2 P05023 1 +Lipid droplet formation 0.595892688235344 0.6421700046309815 0.5207628064446066 1.0 0.8612246467182614 4 Q14534 1 +Carnitine metabolic process 0.4690230075675259 0.6409865621834276 0.5215314136593121 1.0 0.8612246467182614 6 P23786,Q9NVH6,P16435 3 +Myeloid leukocyte migration 0.3379291268926702 0.6392685639749608 0.5226482351623809 1.0 0.8616289130121552 24 Q8N5M9,Q99538,Q07021,P35613,Q08722,O00429,Q9BW27,P04083 8 +Sensory perception 0.3202859604190308 0.6381165496387701 0.5233978142326561 1.0 0.8616289130121552 33 O43924,O76024,Q9H6K4,O60313,P62072,Q9Y5J9,Q14108,Q15555,P50897,Q99797 10 +Negative regulation of cell activation 0.3715174945747356 0.6374839709221418 0.5238096475580503 1.0 0.8616289130121552 15 P09601,Q05655 2 +Positive regulation of small gtpase mediated signal transduction 0.467517584142136 0.6337690914683405 0.526231527296835 1.0 0.8634805203419921 6 Q96AG4 1 +Estrogen metabolic process 0.4955210463148514 0.6323510512616539 0.5271575114593312 1.0 0.8642934046383021 5 O95470,Q53GQ0 2 +Meiotic chromosome segregation 0.3472471540491746 0.6321838459664849 0.5272667517495366 1.0 0.8642934046383021 21 Q9BXW9,Q92791,P46379,Q9BTX1,O60566,O94901,Q15645 7 +Cop9 signalosome assembly 0.6767610269914431 0.6318497460917163 0.5274850639179844 1.0 0.8642934046383021 2 Q99627 1 +Multicellular organism growth 0.3254140917335267 0.6285222690923679 0.5296618630856473 1.0 0.8665458949221041 29 O43464,Q86UL3,O95470,Q99538,Q15363,P42345,O75844,P05067 8 +Negative regulation of response to external stimulus 0.3020268327878548 0.6261884516683622 0.5311913409957301 1.0 0.8681217808943609 44 O75122,O43657,P80303,Q96G23,Q8IXJ6,Q96KB5,P28070,Q9Y5A9,Q07021,P04439,Q05655,P04062,P55011 13 +Negative regulation of cytokine production 0.3429481765702805 0.6234600515575217 0.5329822461825526 1.0 0.8692638944843223 22 P09601,Q07021,P04062,Q9Y639,P04083 5 +G quadruplex dna unwinding 0.4934026644824767 0.6230305963318753 0.5332644159110855 1.0 0.8693071627419491 5 P51530,P22626 2 +Hormone catabolic process 0.6811302200129478 0.6213172406917202 0.5343909122041399 1.0 0.8697377679213634 3 P42892 1 +Porphyrin containing compound metabolic process 0.3594989652841406 0.6209967247421488 0.5346017781672954 1.0 0.8697377679213634 17 P09601,P30519,Q7KZN9 3 +Negative regulation of wound healing 0.4647246877777132 0.6204124489610905 0.534986278496735 1.0 0.8697377679213634 6 O75122,Q05655,P55011 3 +Tetrapyrrole metabolic process 0.3513909677665621 0.6192770625779498 0.5357338523878059 1.0 0.8697866232856194 19 P09601,P30519,Q7KZN9 3 +Regulation of vesicle mediated transport 0.2928272915467913 0.6145272073420829 0.5388669998677083 1.0 0.8726213123972366 112 O75122,Q15907,P98194,P11279,P09601,Q9Y6B6,Q6NUQ1,P18031,P57105,P50897,Q9HCU5,Q9NR31,Q9UHD9,Q8WUM4,Q9P2W9,Q08722,Q96PU5,P61026,O00560,Q4J6C6,P0DP25,P16615,Q9P253,Q8WTV0,Q12907,P04083,Q15042,P05067 28 +Positive regulation of golgi to plasma membrane protein transport 0.678959499506083 0.6137224382173814 0.5393987583556545 1.0 0.873037562543555 3 P98194,O95573 2 +Regulation of extracellular matrix organization 0.4909712088052543 0.6123651826361055 0.540296172296086 1.0 0.8738225117338224 5 Q9Y5U9 1 +Positive regulation of extracellular matrix organization 0.4909712088052543 0.6123651826361055 0.540296172296086 1.0 0.8738225117338224 5 Q9Y5U9 1 +Oligosaccharide catabolic process 0.6784067252793906 0.6117925052118727 0.5406750490565637 1.0 0.8740221225774526 3 P17900 1 +Cell communication by electrical coupling involved in cardiac conduction 0.5878836809472398 0.611279668950842 0.5410144482792498 1.0 0.8743167641146484 4 P0DP25 1 +Neuronal action potential 0.5877879326966259 0.6109124586798731 0.5412575364143901 1.0 0.8743234284471605 4 P04062,P42345 2 +Adaptive immune response 0.3096293540373709 0.6101338716503029 0.5417731306753952 1.0 0.8744311880581037 37 Q9NZ08,P10321,O96028,Q07021,P04439,Q05655,Q96FW1,P04083,Q9NUQ9,P53634,Q03518,O15400 12 +Positive regulation of vasculature development 0.3670238236869236 0.6064915992615652 0.5441883591197585 1.0 0.8765487102293931 15 Q9NZ08,Q86UE4,P09601 3 +Positive regulation of nuclear division 0.4015990636362809 0.6044433956929862 0.545548891653924 1.0 0.877306613577926 11 Q9UJX3,Q8IXJ6,Q9UJX2 3 +Cellular response to virus 0.3466175349507637 0.6041720328337192 0.545729272716593 1.0 0.877306613577926 20 Q99623,O43657,Q9NUD5,Q07021,Q14671 5 +Negative regulation of oxidoreductase activity 0.6758082021606675 0.6027426783813862 0.5466798851014922 1.0 0.8774203221404044 3 Q15070 1 +Platelet derived growth factor receptor signaling pathway 0.4610144066414043 0.6027385053976756 0.5466826616034168 1.0 0.8774203221404044 6 O95470 1 +Cardiac conduction 0.3569203296320542 0.6023701684324536 0.5469277627490952 1.0 0.8774203221404044 17 O75844,Q9HD47 2 +Regulation of phosphoprotein phosphatase activity 0.3612013799877068 0.5980216996837091 0.5498254541027818 1.0 0.8774203221404044 16 P0DP25 1 +Ribonucleoside triphosphate biosynthetic process 0.3232121152562849 0.5977851057493578 0.549983330072167 1.0 0.8774203221404044 28 P24539,P00846 2 +Sulfur compound catabolic process 0.4469386590120185 0.5964165218852776 0.5508970057905092 1.0 0.8774203221404044 8 Q9UJ14,P15586 2 +Negative regulation of mononuclear cell migration 0.666886109282404 0.5956126254470099 0.5514340403219176 1.0 0.877593160530446 2 Q5JRA6 1 +Response to corticosteroid 0.3322124919421418 0.5919568722467149 0.5538794685910275 1.0 0.8786628716883009 24 P0DP25,P04062,P16278,P16435 4 +Protein targeting to vacuole 0.3731583042798773 0.5918739604592749 0.5539349919579517 1.0 0.8786628716883009 13 Q14108,Q96RL7,Q9H9H4,Q99523,Q9Y2T2 5 +Multivesicular body sorting pathway 0.3863936591809743 0.5903960643756901 0.5549251485227908 1.0 0.8792082634671177 12 Q9HD42,Q9BRG1,Q9NZZ3,O43633,Q9H444,Q92783,Q9NP79,Q8WUX9,Q99523,P55072,Q9H3S7 11 +Endosome transport via multivesicular body sorting pathway 0.3863936591809743 0.5903960643756901 0.5549251485227908 1.0 0.8792082634671177 12 Q9HD42,Q9BRG1,Q9NZZ3,O43633,Q9H444,Q92783,Q9NP79,Q8WUX9,Q99523,P55072,Q9H3S7 11 +Protein k11 linked ubiquitination 0.4456666594434796 0.5899708354668822 0.5552102023480661 1.0 0.8792082634671177 8 Q9UJX2 1 +Response to reactive oxygen species 0.3197088554769518 0.589385959424729 0.5556023930722978 1.0 0.8794632411956295 30 Q99720,P09601,Q96P47,P00374 4 +Second messenger mediated signaling 0.3353306270123675 0.5890328824809296 0.5558392155396141 1.0 0.8794632411956295 23 P0DP25,O75844 2 +Regulation of mitochondrial fission 0.4112449112137496 0.5888205920075776 0.555981630747381 1.0 0.8794632411956295 10 Q9NUQ9,O00429,Q9GZY8 3 +Somite rostral caudal axis specification 0.6649111257406044 0.5884495295871057 0.5562306009755953 1.0 0.8794632411956295 2 Q15363 1 +Exit from mitosis 0.3683362366594859 0.58625594402076 0.5577035320551609 1.0 0.8798122734531155 14 P50748,O75122,Q8IXJ6,Q9UJX2 4 +Positive regulation of protein targeting to membrane 0.4470199920024261 0.5848486622925007 0.5586494805417428 1.0 0.8806532081836728 7 P27105 1 +Oocyte differentiation 0.4281214834014649 0.5848445358403368 0.5586522554116691 1.0 0.8806532081836728 9 Q15645,Q8IXJ6,Q9Y5A9 3 +Negative regulation of anoikis 0.6703938683613572 0.5840086182852671 0.5592145137415998 1.0 0.8811706738925259 3 Q07820 1 +Golgi to lysosome transport 0.484328665784587 0.5834141283217532 0.559614549119418 1.0 0.8811706738925259 5 P11279 1 +Bile acid metabolic process 0.3979871962875413 0.5828081563629773 0.560022453606801 1.0 0.8811706738925259 11 O14734,Q9H2C2,Q06520,Q96SU4,O15118 5 +Phagosome maturation 0.6632653061224505 0.5825025268887721 0.5602282399621927 1.0 0.8811706738925259 2 P61106 1 +Phagolysosome assembly 0.6632653061224505 0.5825025268887721 0.5602282399621927 1.0 0.8811706738925259 2 P61106 1 +Regulation of long chain fatty acid import across plasma membrane 0.6629361421988164 0.5813155778246708 0.5610277835248423 1.0 0.8820366062027638 2 P31751 1 +Positive regulation of jnk cascade 0.4562204302175501 0.58002764374239 0.5618959761155637 1.0 0.8827016372196054 6 P05067 1 +Negative regulation of nitric oxide metabolic process 0.6682700283143015 0.5767063608687233 0.5641378347354125 1.0 0.8835541693358598 3 P06280 1 +Peptidyl arginine n methylation 0.4827018121910962 0.5763670620783646 0.564367102927088 1.0 0.8835541693358598 5 Q6P2P2,O60678,Q99873,Q86X55 4 +Peptidyl arginine methylation 0.4827018121910962 0.5763670620783646 0.564367102927088 1.0 0.8835541693358598 5 Q6P2P2,O60678,Q99873,Q86X55 4 +Regulation of histone h3 k14 acetylation 0.6609611586570119 0.5742112185691451 0.5658248786358273 1.0 0.8840665999531264 2 Q03164 1 +Ventricular septum morphogenesis 0.6671056964109228 0.5727144774998466 0.566838033296752 1.0 0.8847110029441756 3 O96028,Q96T37 2 +Glycerol 3 phosphate metabolic process 0.6596445029624642 0.5694916418285867 0.5690225412684644 1.0 0.8864478608584215 2 P43304 1 +Positive regulation of protein binding 0.3356157777871466 0.5652599265927609 0.5718969813617585 1.0 0.8877747035814824 22 Q9BUN8,P05067 2 +Regulation of nitric oxide metabolic process 0.4243534399178014 0.564632769428571 0.5723235714698329 1.0 0.8878908030906171 9 Q08722,P06280 2 +Response to amyloid beta 0.4521918897280828 0.5610591802633135 0.5747571941140068 1.0 0.8894995830494051 6 P05067 1 +Cellular response to amyloid beta 0.4521918897280828 0.5610591802633135 0.5747571941140068 1.0 0.8894995830494051 6 P05067 1 +Interleukin 12 production 0.4790179692225617 0.5604761392485457 0.5751547104335231 1.0 0.8894995830494051 5 Q08722 1 +Long chain fatty acid import across plasma membrane 0.6631544287125456 0.5592288021971027 0.576005578775963 1.0 0.8894995830494051 3 P31751,P11166 2 +Positive regulation of leukocyte migration 0.350863679632659 0.5588372622315754 0.5762727894184978 1.0 0.8896744837366947 17 Q99538,Q07021,Q08722,O00429,Q5JRA6,P05067 6 +Negative regulation of amyloid fibril formation 0.5737812911725955 0.557767292759017 0.5770032996919809 1.0 0.8898631836970622 4 Q9UHV9,P61758,O15212 3 +Regulation of gene silencing by rna 0.3554405224486379 0.5576329741463639 0.5770950351163138 1.0 0.8898631836970622 16 Q01085,Q08211,Q14671,Q06787,Q9HAV4,O75844 6 +Sodium ion transmembrane transport 0.3553830266692033 0.5572313470048522 0.5773693749167013 1.0 0.89004803656395 16 Q9HD47,P05023,Q96PU5,P27105,P55011 5 +Histone h3 deacetylation 0.4782202523543766 0.5570474917741945 0.5774949815591142 1.0 0.89004803656395 5 Q9H4L7,Q8IXJ6 2 +Regulation of thymocyte apoptotic process 0.6560236998025031 0.5565827507873239 0.5778125417361726 1.0 0.8901057962373048 2 P04637 1 +Negative regulation of t cell apoptotic process 0.6560236998025029 0.5565827507873222 0.5778125417361737 1.0 0.8901057962373048 2 Q9HCL2 1 +Regulation of torc2 signaling 0.654377880184333 0.5507495477550186 0.5818053739873428 1.0 0.8934420340055116 2 Q9Y4R8 1 +Positive regulation of histone h4 acetylation 0.6543778801843332 0.5507495477550186 0.5818053739873428 1.0 0.8934420340055116 2 O95251 1 +Detection of external biotic stimulus 0.6599049219025569 0.5482105966951659 0.5835473068061678 1.0 0.8936796428803168 3 Q8WTV0 1 +Detection of biotic stimulus 0.6599049219025569 0.5482105966951659 0.5835473068061678 1.0 0.8936796428803168 3 Q8WTV0 1 +Diacylglycerol metabolic process 0.6598617056305444 0.5480645103078596 0.5836476081806474 1.0 0.8936796428803168 3 Q8NCC3,Q86UL3 2 +Vasculogenesis 0.4393244723170472 0.5470275515199364 0.5843598038953239 1.0 0.893995882122197 7 O95470 1 +Smoothened signaling pathway 0.3491450364214988 0.5465451222574269 0.584691279857692 1.0 0.893995882122197 17 O43805 1 +Negative regulation of growth 0.3228752424114634 0.5443573851879033 0.5861955648244912 1.0 0.8951048665713829 25 P50897,Q9NQC3 2 +Multicellular organismal movement 0.4385779246714665 0.543379805394862 0.5868683270844444 1.0 0.8951048665713829 7 P78417 1 +Ribonucleoprotein complex disassembly 0.4747940691927567 0.5423735295952634 0.5875612110499999 1.0 0.8951048665713829 5 P33176,Q14562,Q9UBB9,Q07866 4 +Multicellular organismal signaling 0.3295277664664665 0.5422791068953757 0.587626246417579 1.0 0.8951048665713829 23 P0DP25,O75844,P04062,Q9HD47 4 +Cellular response to chemical stress 0.2695854865477207 0.5401619340694913 0.5890853617500291 1.0 0.8961767734043048 79 O43464,Q99720,P09601,Q7Z2K6,Q9BPX6,Q9BXW9,Q8TED1,Q96P47,Q6NUK1,P07237,P04062,Q9NR28,Q8IXJ6,Q07820,P16615,P00374,O75569,P23246,Q15118,O75915,O95202,Q9NP80,Q05655,P04083,Q8TDW0,Q8N0U8 26 +Positive regulation of mitochondrial fission 0.4356162849748337 0.5393831183770139 0.589622527046751 1.0 0.8965647803610405 8 O00429,O14965,Q9GZY8 3 +Regulation of phospholipase a2 activity 0.6569983506017425 0.5384119932534679 0.5902926482873485 1.0 0.8966601557095123 3 P50897 1 +Regulation of response to osmotic stress 0.5681240372237174 0.5366462589498497 0.5915119842457728 1.0 0.8979341227289543 4 Q9BPX6,O95202 2 +Negative regulation of peptidyl threonine phosphorylation 0.567746723837616 0.5352450873315922 0.5924803924941671 1.0 0.8988391245015707 4 P0DP25 1 +Vesicle targeting to from or within golgi 0.3643011130630488 0.5340480321557468 0.5933083028912101 1.0 0.8993695288533838 13 P49755,O00743,Q9Y6B6,Q15363,Q9HCU5,Q9NR31 6 +Import into cell 0.3284956416427652 0.534000965601781 0.5933408660062227 1.0 0.8993695288533838 23 Q8N697,P54709,P31751,O75955,O75915,Q15758,P05023,P08195,P11166,Q15041,Q8TDW0,Q99808,P55011 13 +Granulocyte activation 0.4455473134989287 0.5300229790858875 0.5960959986720864 1.0 0.9005909597242171 6 Q05655 1 +L aspartate transmembrane transport 0.5658804847092179 0.5283288635453643 0.5972711016482584 1.0 0.9006681231239564 4 Q9H936,Q9UJS0 2 +Regulation of muscle contraction 0.3413903482911385 0.5263865596952787 0.5986196520997764 1.0 0.9014447474989512 18 P0DP25,Q9HD47 2 +Regulation of skeletal muscle cell differentiation 0.5642292490118557 0.522229295730794 0.6015106908905468 1.0 0.9031193483518284 4 Q9BRT2,P17844,Q9BYT8 3 +Monoubiquitinated protein deubiquitination 0.5640517324503797 0.5215746825946498 0.6019664945842322 1.0 0.9031193483518284 4 Q9Y6J9 1 +Behavior 0.2737149511106795 0.5215283476533027 0.6019987632611556 1.0 0.9031193483518284 75 O43464,P54802,Q99538,Q15154,P10253,Q9BPZ3,P50897,P17900,O00264,Q96RL7,P04062,O75844,P50416,O76024,P51790,P42345,Q92542,O75915,P04080,Q14671,Q9Y639,P05067,O15118 23 +Regulation of heart rate 0.3750373129773672 0.5197992780715331 0.6032034825727501 1.0 0.9042361639699056 12 P0DP25,Q9HD47 2 +Neuromuscular junction development 0.4335494960608543 0.5189153117854509 0.6038197996381531 1.0 0.9043538691688372 7 P05067 1 +Vesicle targeting rough er to cis golgi 0.386899555436596 0.5169749411089548 0.6051736517978883 1.0 0.9043538691688372 11 P49755,O00743,Q9Y6B6,Q15363,Q9HCU5,Q9NR31 6 +Left right axis specification 0.644502962475314 0.5162199165978115 0.6057008214366908 1.0 0.9043538691688372 2 Q9HCM4 1 +Left right pattern formation 0.644502962475314 0.5162199165978115 0.6057008214366908 1.0 0.9043538691688372 2 Q9HCM4 1 +Positive regulation of keratinocyte proliferation 0.6445029624753142 0.5162199165978113 0.605700821436691 1.0 0.9043538691688372 2 Q6ZWJ1 1 +Pulmonary valve morphogenesis 0.6445029624753141 0.5162199165978113 0.605700821436691 1.0 0.9043538691688372 2 O94813 1 +Mature b cell differentiation 0.6445029624753142 0.5162199165978113 0.605700821436691 1.0 0.9043538691688372 2 P00813 1 +Pulmonary valve development 0.6445029624753141 0.5162199165978113 0.605700821436691 1.0 0.9043538691688372 2 O94813 1 +Cardiac atrium development 0.6445029624753055 0.5162199165977817 0.6057008214367117 1.0 0.9043538691688372 2 O96028 1 +Cardiac atrium morphogenesis 0.6445029624753055 0.5162199165977817 0.6057008214367117 1.0 0.9043538691688372 2 O96028 1 +Atrial septum development 0.6445029624753055 0.5162199165977817 0.6057008214367117 1.0 0.9043538691688372 2 O96028 1 +Atrial septum morphogenesis 0.6445029624753055 0.5162199165977817 0.6057008214367117 1.0 0.9043538691688372 2 O96028 1 +Sequestering of zinc ion 0.6438446346280462 0.5139474081078433 0.6072887608077724 1.0 0.9051271681504904 2 O14617 1 +Natural killer cell mediated immunity 0.4300149391350553 0.51147836901934 0.6090161312023927 1.0 0.9071651259154722 8 P11279 1 +Regulation of sodium ion transmembrane transport 0.3607843749302017 0.511281903380725 0.6091536748595399 1.0 0.9071651259154722 13 Q9HD47 1 +Hemostasis 0.3286823840276953 0.5107258118671256 0.6095430639359152 1.0 0.9073135841181512 22 P61225,Q9UIJ7,P38435,Q9BWH2 4 +Regulation of hexokinase activity 0.5609364055794503 0.5101225606437927 0.6099656004823917 1.0 0.9073135841181512 4 Q9Y6N1 1 +Pore complex assembly 0.3730857811608246 0.5077774400174644 0.611609432753438 1.0 0.9080564248028152 12 Q9NQC3,Q9BTX1 2 +Negative regulation of cytokine production involved in inflammatory response 0.6418696510862423 0.507152636648555 0.6120477247044742 1.0 0.9084949412007562 2 Q53EL6 1 +Negative regulation of double strand break repair via nonhomologous end joining 0.6415404871626085 0.5060235157017804 0.6128401415347056 1.0 0.9092464844992036 2 Q9UBB9 1 +Positive regulation of cold induced thermogenesis 0.3594861045105516 0.5029081140139637 0.615028876123209 1.0 0.9098863677781668 13 P23786,Q16836 2 +Leukocyte differentiation 0.2878747519938066 0.501732923856376 0.6158554017326479 1.0 0.9098863677781668 57 P24390,Q86WC4,Q14739,P04062,O96005,P05067 6 +Toll like receptor 7 signaling pathway 0.6402238314680726 0.5015166567688617 0.6160075581557232 1.0 0.9098863677781668 2 Q8N697 1 +Chemokine c c motif ligand 5 production 0.6402238314680726 0.5015166567688617 0.6160075581557232 1.0 0.9098863677781668 2 Q7Z434 1 +Regulation of toll like receptor 7 signaling pathway 0.6402238314680726 0.5015166567688617 0.6160075581557232 1.0 0.9098863677781668 2 Q8N697 1 +Toll like receptor 8 signaling pathway 0.6402238314680726 0.5015166567688617 0.6160075581557232 1.0 0.9098863677781668 2 Q8N697 1 +Positive regulation of chemokine c c motif ligand 5 production 0.6402238314680726 0.5015166567688617 0.6160075581557232 1.0 0.9098863677781668 2 Q7Z434 1 +Prostanoid biosynthetic process 0.4280010574761836 0.5015012081677662 0.6160184277730711 1.0 0.9098863677781668 8 Q8NCG7,Q9NP80 2 +Positive regulation of translational initiation 0.3715860877481995 0.4985632746141932 0.6180870829386986 1.0 0.9110764144615882 12 Q7Z739,Q9Y5A9,Q07666,P42345,Q13217 5 +Regulation of action potential 0.37147799972069 0.4979000124422885 0.6185545185423447 1.0 0.9113427259747664 12 P0DP25,P04062,Q9HD47 3 +Positive regulation of mononuclear cell migration 0.3831332269870168 0.4948393695850844 0.62071351151384 1.0 0.913464940769152 11 Q07021,Q08722,P05067,Q99538 4 +Protein autoprocessing 0.4374276882646558 0.4925579969564078 0.6223249328070193 1.0 0.914777352664527 6 Q9UG56 1 +Regulation of membrane lipid distribution 0.4276776815787827 0.4905932519407814 0.623714160119067 1.0 0.9148880881549724 7 Q96CP7,Q05655,Q96GC9 3 +Amyloid beta clearance 0.4100058453342367 0.4885707850063165 0.6251456005939331 1.0 0.915915768047533 9 Q15907 1 +L serine transport 0.6362738643844648 0.4880896560617832 0.6254863375357651 1.0 0.915915768047533 2 Q15758 1 +Serine transport 0.6362738643844648 0.4880896560617832 0.6254863375357651 1.0 0.915915768047533 2 Q15758 1 +Positive regulation of protein kinase b signaling 0.3453915897612047 0.4879411946915782 0.6255914944767256 1.0 0.915915768047533 16 Q07021,Q9NQC3,Q86UE4,O00165 4 +Positive regulation of posttranscriptional gene silencing 0.3695841958956426 0.4862976663202986 0.6267561335939624 1.0 0.9161952417200748 12 Q01085,Q08211,P51114,Q14671,Q06787,Q9HAV4 6 +Regulation of sodium ion transport 0.3488193114585227 0.4826818047015825 0.6293216845447591 1.0 0.9166553774470346 15 P05023,Q96PU5,P27105,Q9HD47 4 +Regulation of defense response to virus by host 0.4256511704582905 0.4808839973782879 0.6305989468082978 1.0 0.9166553774470346 7 Q08211,Q7Z434,P42224,O94826,O60828,P07900 6 +Regulation of phosphatase activity 0.3325062777240479 0.4784953221163042 0.6322977029604757 1.0 0.9166553774470346 19 P0DP25 1 +Cell surface receptor signaling pathway involved in heart development 0.6333113890717592 0.478113226229115 0.6325696188378251 1.0 0.9166553774470346 2 Q04721 1 +Foregut morphogenesis 0.6333113890717593 0.4781132262291147 0.6325696188378254 1.0 0.9166553774470346 2 Q9HCM4 1 +Synaptic vesicle clustering 0.6333113890717591 0.4781132262291144 0.6325696188378256 1.0 0.9166553774470346 2 P19022 1 +Metanephric nephron morphogenesis 0.6333113890717591 0.4781132262291144 0.6325696188378256 1.0 0.9166553774470346 2 P42224 1 +Metanephric renal vesicle morphogenesis 0.6333113890717591 0.4781132262291144 0.6325696188378256 1.0 0.9166553774470346 2 P42224 1 +Positive regulation of mesenchymal cell proliferation 0.6333113890717591 0.4781132262291144 0.6325696188378256 1.0 0.9166553774470346 2 P42224 1 +Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 0.6333113890717591 0.4781132262291144 0.6325696188378256 1.0 0.9166553774470346 2 P42224 1 +Mesenchymal to epithelial transition involved in metanephros morphogenesis 0.6333113890717591 0.4781132262291144 0.6325696188378256 1.0 0.9166553774470346 2 P42224 1 +Detection of muscle stretch 0.6333113890717591 0.4781132262291144 0.6325696188378256 1.0 0.9166553774470346 2 P19022 1 +Regulation of morphogenesis of an epithelium 0.6333113890717382 0.4781132262290439 0.6325696188378758 1.0 0.9166553774470346 2 Q99623 1 +Positive regulation of fibroblast growth factor receptor signaling pathway 0.6333113890717372 0.4781132262290417 0.6325696188378773 1.0 0.9166553774470346 2 Q9Y639 1 +Regulation of fibroblast growth factor receptor signaling pathway 0.6333113890717372 0.4781132262290417 0.6325696188378773 1.0 0.9166553774470346 2 Q9Y639 1 +Cellular response to xenobiotic stimulus 0.3181762513965306 0.4772272541986874 0.633200305757867 1.0 0.9166553774470346 24 O43169,P78417,P16435 3 +Negative regulation of gliogenesis 0.4587774043985748 0.4749892011113795 0.6347946703694396 1.0 0.916989755651854 5 Q96G23 1 +Cellular glucose homeostasis 0.3144283072481015 0.4741858004783675 0.6353674181741338 1.0 0.9172733539223368 25 P52789,Q15907,Q8N5M9 3 +Zinc ion homeostasis 0.5507246376811528 0.4730809824035502 0.6361554041364537 1.0 0.9172876017902222 4 O14617,O00203,Q8NEW0 3 +Regulation of cellular response to transforming growth factor beta stimulus 0.3673520359571742 0.4726689345936199 0.6364493932285133 1.0 0.91750336660477 12 P62942 1 +Programmed necrotic cell death 0.3792986654797137 0.4724363502536821 0.6366153634788312 1.0 0.9175345238710774 11 Q13510 1 +Neutral amino acid transport 0.6364833717484324 0.4708834947523784 0.6377239352818838 1.0 0.9185074399845125 3 P08195,Q15758 2 +Mitochondrion localization 0.3428102280878992 0.4702193403818893 0.6381983177650854 1.0 0.9189786134231128 16 O95140,O75153,Q9UH62,O60313,O00429,Q8IWA4,Q9NVT9 7 +Autophagy of mitochondrion 0.3059385909479622 0.4661301481156698 0.6411223447435139 1.0 0.920279901375256 30 O43464,Q99623,O95140,Q9UII2,Q9NQ88,P05141,P52789,P12235,P27544,O95352,P04062,O00429,Q9BWH2,P21796,O75143,O00165 16 +Embryonic digit morphogenesis 0.4314871845940892 0.4654999034794311 0.6415735060189438 1.0 0.9205059151820332 6 P42892 1 +Late endosome to lysosome transport 0.4220243982855222 0.4635961397072911 0.6429371206025662 1.0 0.921000516675917 7 Q9HD42,O43633,Q9NZZ3,Q9H444,Q96QK1,Q8WUX9 6 +Branching involved in blood vessel morphogenesis 0.6335199209746346 0.4613804932968483 0.6445256440878584 1.0 0.9210915970420078 3 Q13043,Q96T37 2 +Positive regulation of smoothened signaling pathway 0.4553430529451366 0.4608241305711634 0.6449247877597599 1.0 0.9210915970420078 5 P16435 1 +Positive regulation of interferon gamma production 0.5463845354025086 0.4575809686856417 0.6472535189256372 1.0 0.9215230040874944 4 Q9NUQ9 1 +Regulation of epithelial to mesenchymal transition 0.4187602929167551 0.4561318088262991 0.6482951977640243 1.0 0.9215230040874944 8 O75122,O00560 2 +Protein targeting to lysosome 0.4034718607794298 0.4544756943462979 0.6494864820864379 1.0 0.9215230040874944 9 Q9Y2T2 1 +Adenosine metabolic process 0.6250822909809102 0.4508370048569757 0.6521070286543438 1.0 0.9215230040874944 2 P00813 1 +Positive regulation of establishment of protein localization to mitochondrion 0.3867441991673961 0.4504759670531958 0.6523672794282835 1.0 0.9215230040874944 10 P55786,O14737,Q9Y371 3 +Arf protein signal transduction 0.6298979255844489 0.4498575205999183 0.6528131791996878 1.0 0.9215230040874944 3 Q15555,Q92538 2 +Erythrocyte maturation 0.6244239631336419 0.4486833139962651 0.6536601232321959 1.0 0.9215230040874944 2 P11413 1 +Response to acid chemical 0.3260048121271598 0.4484363529945971 0.6538383106881334 1.0 0.9215230040874944 20 Q14103,Q99729,Q8NEB9,O00410,O94874,P42345,Q15388,Q9UQB8,O95831,Q9P2J5 10 +Viral budding 0.3861386138613819 0.4471219892086328 0.6547869830670907 1.0 0.9216466129711164 10 Q9HD42,O43633,Q9NZZ3,Q9H444,Q8WUM4,Q9NP79,Q8WUX9,Q9H9H4,Q99816 9 +Body fluid secretion 0.3468364570824254 0.44429654196681 0.6568282010371549 1.0 0.9216466129711164 14 Q13505,P52789 2 +Granulocyte migration 0.3346405411298944 0.4440997327842456 0.6569704796640539 1.0 0.9216466129711164 17 Q07021,P35613,Q8N5M9,P04083 4 +Positive regulation of defense response to virus by host 0.425510876730391 0.4386056488252779 0.6609473032445443 1.0 0.9241049404800536 6 Q7Z434,P42224,O94826,O60828,P07900 5 +Torc1 signaling 0.4248878886204925 0.43582197812711 0.6629658965363601 1.0 0.9257054565872376 6 Q9Y4R8,P42345,Q9P2J5 3 +Regulation of epithelial cell apoptotic process 0.3996833076838657 0.4348846276505715 0.663646173232809 1.0 0.9257346897977674 9 P09601 1 +Positive regulation of toll like receptor 3 signaling pathway 0.6201448321264005 0.4347897171570703 0.6637150694475182 1.0 0.9257346897977674 2 O75955 1 +Regulation of synaptic transmission dopaminergic 0.6201448321264005 0.4347897171570703 0.6637150694475182 1.0 0.9257346897977674 2 O75955 1 +Positive regulation of heterotypic cell cell adhesion 0.6201448321264005 0.4347897171570703 0.6637150694475182 1.0 0.9257346897977674 2 O75955 1 +Transmission of nerve impulse 0.4238305691908887 0.4311064560351421 0.6663909665763799 1.0 0.9278381124993365 6 P04062,P42345 2 +Establishment of protein localization to vacuole 0.3365742555083882 0.42775756792746 0.6688276326028708 1.0 0.9287892577723066 16 Q14108,Q96RL7,Q9H9H4,Q99523,O14617,Q9Y2T2 6 +Rhythmic behavior 0.5375418439397445 0.4264795447584167 0.6697584500961324 1.0 0.9296756297905696 4 P42345,P54802 2 +Detection of stimulus 0.3474663001412834 0.4262685084914511 0.6699122021462363 1.0 0.9296860167776152 13 P0DP25,P04439,Q8WTV0 3 +Positive regulation of catabolic process 0.2989210049974505 0.4248340883306743 0.6709576259131227 1.0 0.9301133972888392 145 O60506,P05141,P09601,Q7Z739,Q9Y5A9,Q86UE4,O75396,P18031,Q5PRF9,Q8NF37,Q9P0J0,Q14103,Q9HCE1,Q9UHD9,P51572,P46379,P12235,O15269,Q96PU5,P04062,P53634,Q13190,P48729,Q6ZXV5,Q676U5,P50416,Q8IXJ6,P21796,O15270,P67809,O14965,Q96HY6,Q08211,Q9UBS8,Q92945,Q8NCG7,Q9BXS4,Q9Y5A7,Q05655,Q969T7,Q14671,Q9Y371,Q06787,Q9HBH5,Q15042,A5YKK6,Q9BYJ9,P05067 48 +T cell mediated immunity 0.3973981240504982 0.4231350982420814 0.6721966959029695 1.0 0.930621258801846 9 Q9NUQ9,P04439,O15400 3 +Positive regulation of protein localization to cell periphery 0.3270311553088037 0.4228522843574856 0.6724030380797024 1.0 0.9306636015830252 18 O15258,Q13277,O00264,Q9HD47 4 +Xenobiotic transport 0.6203490286466872 0.4199803782739805 0.6744997879237378 1.0 0.9313753317495752 3 P08183,P11166 2 +Positive regulation of skeletal muscle tissue development 0.6203490286466864 0.419980378273978 0.6744997879237395 1.0 0.9313753317495752 3 P35222,O75955 2 +Positive regulation of muscle tissue development 0.6203490286466864 0.419980378273978 0.6744997879237395 1.0 0.9313753317495752 3 P35222,O75955 2 +Positive regulation of cell adhesion molecule production 0.6203490286466858 0.4199803782739768 0.6744997879237404 1.0 0.9313753317495752 3 O75955,Q5KU26 2 +Protein folding in endoplasmic reticulum 0.3963174507418051 0.417597014424467 0.6762417800143856 1.0 0.9328614131095214 9 Q96HE7,P07237,P27824 3 +Regulation of cardiac muscle cell action potential 0.3961931315333228 0.4169606883873027 0.67670716215811 1.0 0.9328614131095214 9 P0DP25,Q9HD47 2 +Negative regulation of mitochondrion organization 0.3456211050112903 0.4146603340421369 0.6783905737580598 1.0 0.9341097241781257 13 P05141,Q96E52,Q9H3K2 3 +Regulation of neurotransmitter uptake 0.6183733947974919 0.4138926960157778 0.6789526932316505 1.0 0.9343325884269272 3 P41440,O75955 2 +Striated muscle contraction 0.3235221254797141 0.4130343760897446 0.6795814279889372 1.0 0.9343325884269272 19 Q9HD47,P0DP25,P78417,P16615,P05023,P10253 6 +Sodium ion homeostasis 0.4196602220180204 0.412618367947032 0.679886241657921 1.0 0.9345495138360176 6 P05023,Q96PU5,P55011 3 +Regulation of natural killer cell mediated immunity 0.5334760113424607 0.412405108821463 0.6800425192178967 1.0 0.9345622166808544 4 P11279 1 +Negative regulation of rna catabolic process 0.2982666749186567 0.4088101941038019 0.6826789582267683 1.0 0.93676758602965 31 O60506,Q13151,Q14103,Q99729,P67809,P98175,P07910,Q08211,Q14011,Q06787,Q92804,P35637 12 +Sensory perception of mechanical stimulus 0.3373002807164908 0.4062363612998224 0.6845689395697443 1.0 0.9390272126078516 15 Q14108,P62072,Q9Y5J9 3 +Protein hexamerization 0.4177048322784406 0.4040125050379997 0.6862035235338426 1.0 0.9390272126078516 6 Q8TDW0,O95202 2 +Steroid catabolic process 0.5302084604295925 0.401201595189889 0.6882717063877759 1.0 0.9397135899550926 4 Q8WTV0 1 +Female meiosis i 0.5290690520467625 0.3973179144030774 0.6911330385389749 1.0 0.9400660950165228 4 Q15645 1 +Late endosome to vacuole transport via multivesicular body sorting pathway 0.4075173095944572 0.3956888519638684 0.6923345805563978 1.0 0.9408631798928132 7 Q9BRG1,Q9NZZ3,Q9H444,Q92783,Q8WUX9,Q9H3S7 6 +Negative regulation of immune effector process 0.3915205487306875 0.3931623855758611 0.6941995492753674 1.0 0.9411917832914872 9 P09601,Q08722 2 +Negative regulation of receptor mediated endocytosis 0.3652119708917696 0.3914596099525113 0.6954575380372245 1.0 0.9411917832914872 11 P05067 1 +Regulation of cartilage development 0.5272577235623752 0.3911688879483093 0.695672403638476 1.0 0.9411917832914872 4 P16435 1 +Regulation of chondrocyte differentiation 0.5272577235623752 0.3911688879483093 0.695672403638476 1.0 0.9411917832914872 4 P16435 1 +Regulation of cyclin dependent protein kinase activity 0.3311343440598602 0.3911635236983218 0.6956763684555392 1.0 0.9411917832914872 16 Q99640 1 +Positive regulation of rna export from nucleus 0.5267979119750424 0.3896128438243486 0.6968228532475909 1.0 0.9411984713465196 4 Q08211 1 +Positive regulation of nucleobase containing compound transport 0.5267979119750424 0.3896128438243486 0.6968228532475909 1.0 0.9411984713465196 4 Q08211 1 +Phosphatidylserine acyl chain remodeling 0.6050032916392273 0.3871538011705843 0.6986423496118748 1.0 0.941996345806762 2 Q6P1A2 1 +Sodium ion transport 0.3198084735911791 0.3863391547898801 0.6992455058925628 1.0 0.9420708986043144 19 Q9HD47,P05023,Q96PU5,P27105,P55011 5 +Toll like receptor 3 signaling pathway 0.5256916996047355 0.3858775273270514 0.6995873746873804 1.0 0.9420708986043144 4 P41440,O75955,Q5KU26 3 +Late endosome to vacuole transport 0.3749174917491714 0.3856779898930965 0.6997351655618265 1.0 0.9420708986043144 10 Q9BRG1,Q9HD42,Q9NZZ3,O43633,Q9H444,Q92783,Q9NP79,Q8WUX9,Q9H3S7 9 +Ectoderm development 0.6081659532433286 0.3829754029857313 0.7017380018325714 1.0 0.9437678247244654 3 P35222,Q9HCM4 2 +Negative regulation of release of cytochrome c from mitochondria 0.4355483607162591 0.3814251479610633 0.7028878035248414 1.0 0.9447266014924868 5 Q9H3K2 1 +Glycoprotein catabolic process 0.6075074086269279 0.3810123605401938 0.7031940767245053 1.0 0.9447266014924868 3 Q8TCJ2,O00462 2 +Fc receptor mediated stimulatory signaling pathway 0.4346047756963806 0.3777438090620746 0.7056209199153689 1.0 0.9464260305128512 5 Q08722 1 +Positive regulation of b cell proliferation 0.6025426992764595 0.3663403345923607 0.7141111356839924 1.0 0.9535483988250956 3 P02786 1 +Positive regulation of interleukin 2 production 0.4086996746817534 0.3649282955931202 0.71516493192083 1.0 0.9539050422902908 6 P04083 1 +Positive regulation of amyloid precursor protein biosynthetic process 0.6010501132299374 0.3619738412281729 0.717371578499397 1.0 0.9556935135070568 3 Q92542 1 +Neuron projection regeneration 0.3852341244169796 0.3615279555033606 0.717704810678216 1.0 0.9558505562087536 9 Q96G23 1 +Gdp metabolic process 0.5182360384583797 0.3610112975865415 0.7180910015570796 1.0 0.9558505562087536 4 Q14168 1 +Negative regulation of locomotion 0.2782370121203385 0.3580901299669481 0.7202758651242802 1.0 0.9565258267518348 40 P57105,P09601,Q96G23 3 +B cell homeostasis 0.5947992100065838 0.3564689721951613 0.7214893845826191 1.0 0.9565258267518348 2 P00813 1 +Positive regulation of fatty acid transport 0.5947992100065811 0.3564689721951542 0.7214893845826245 1.0 0.9565258267518348 2 P33121 1 +G protein coupled receptor signaling pathway 0.2780379931464198 0.3560908673832398 0.7217725163473192 1.0 0.9565258267518348 40 P07602,P0DP25,Q9NZJ7,Q99720,Q8NCG7,P42892,P04083 7 +Regulation of protein localization to membrane 0.2762131051264073 0.3559762720533232 0.721858334945737 1.0 0.9565258267518348 42 O15258,Q9GZY8,Q9HD47,Q9BXS4,O00264,Q13277,Q9UEU0,O14737,P27105,O15400 10 +Torc2 signaling 0.5982877839973597 0.353947951919606 0.7233778897153078 1.0 0.9573145073714752 3 Q9Y4R8,Q9NWS0 2 +Farnesyl diphosphate metabolic process 0.5980713076771971 0.3533220363981285 0.7238470268814474 1.0 0.9573145073714752 3 P14324 1 +G protein coupled purinergic receptor signaling pathway 0.5934825543120479 0.3525966691896677 0.7243908350192909 1.0 0.9574190366776072 2 P00813 1 +Purinergic nucleotide receptor signaling pathway 0.5934825543120479 0.3525966691896677 0.7243908350192909 1.0 0.9574190366776072 2 P00813 1 +Unsaturated fatty acid biosynthetic process 0.3581673083569553 0.3518646366558071 0.7249397811804015 1.0 0.9577462584042054 11 Q8NCG7,P04083,O95864,Q9NP80 4 +Regulation of phosphatidylcholine metabolic process 0.5143416065523942 0.3482429739288409 0.7276577166449831 1.0 0.9592503792887532 4 Q8WTV0 1 +Learning 0.3099828243561539 0.3481750830286306 0.7277086993211233 1.0 0.9592503792887532 21 P50897,P05067 2 +Female sex differentiation 0.3825443034711262 0.348135520702125 0.7277384092086796 1.0 0.9592503792887532 9 O95470 1 +Development of primary female sexual characteristics 0.3825443034711262 0.348135520702125 0.7277384092086796 1.0 0.9592503792887532 9 O95470 1 +Regulation of establishment of protein localization to mitochondrion 0.3246108471422761 0.3479006783415121 0.7279147758168714 1.0 0.9592821131877004 16 O43464,O14737,Q9Y371,P55786,O00165 5 +Regulation of histamine secretion by mast cell 0.5905200789993433 0.343958425858719 0.7308775519330055 1.0 0.9600036619314286 2 P51809 1 +Negative regulation of peptide secretion 0.395953221325229 0.3431777559515781 0.7314647378623953 1.0 0.9602083233602664 7 Q8N5M9 1 +Negative regulation of hormone secretion 0.395953221325229 0.3431777559515781 0.7314647378623953 1.0 0.9602083233602664 7 Q8N5M9 1 +Mononuclear cell migration 0.3011735554719744 0.3421573623263969 0.7322324707114953 1.0 0.960761809117493 24 P05067,Q99538,Q07021,Q08722,P04062,P04083,Q5JRA6,P55011 8 +Adipose tissue development 0.3666925349868414 0.3415839513318064 0.7326640164871756 1.0 0.960761809117493 10 P43490,Q6IAN0,P35610,O15173,O15270 5 +Fatty acid beta oxidation using acyl coa oxidase 0.4247691389641654 0.3399874892656917 0.7338659494607593 1.0 0.96129431752724 5 Q15067,O15254 2 +Positive regulation of exocytosis 0.3232211653087131 0.3387796444555194 0.7347757368123964 1.0 0.9620640278693108 16 O75122,O00560,P11279,Q8WUM4 4 +Folic acid containing compound metabolic process 0.3301257877817377 0.3379161578381949 0.7354263708747941 1.0 0.9620746124138312 14 P00374,Q9H2D1 2 +Mesenchymal to epithelial transition 0.5108695652173851 0.3369914724145902 0.7361233285426938 1.0 0.9620746124138312 4 P42224,P35222,Q9BRX2 3 +Negative regulation of calcium ion dependent exocytosis 0.5878867676102715 0.3363674381936439 0.7365938009506809 1.0 0.9620746124138312 2 P04899 1 +Neutrophil activation involved in immune response 0.5878867676102716 0.3363674381936436 0.7365938009506812 1.0 0.9620746124138312 2 P51809 1 +Neutrophil degranulation 0.5878867676102716 0.3363674381936436 0.7365938009506812 1.0 0.9620746124138312 2 P51809 1 +Response to sterol depletion 0.4018480291391945 0.3358351687875908 0.7369951680054969 1.0 0.9620746124138312 6 Q6P1A2,O75477,O94905,Q15363 4 +Cellular response to sterol depletion 0.4018480291391942 0.3358351687875897 0.7369951680054978 1.0 0.9620746124138312 6 Q6P1A2,O75477,O94905,Q15363 4 +Positive regulation of t cell receptor signaling pathway 0.5872284397629925 0.3344826731809242 0.7380153635426028 1.0 0.9625803590645404 2 P00813 1 +Positive regulation of antigen receptor mediated signaling pathway 0.5872284397629925 0.3344826731809242 0.7380153635426028 1.0 0.9625803590645404 2 P00813 1 +Regulation of granulocyte chemotaxis 0.379477706971937 0.3329777299536364 0.7391510937680923 1.0 0.963501231002237 9 Q07021,O00429,Q8NHP6 3 +Cellular response to topologically incorrect protein 0.2858082690419686 0.3320942314190095 0.7398181058518707 1.0 0.96378025841248 34 Q9BUN8,Q96HY6,O76024,Q7Z2K6,P57088,P48723,Q9Y4P3,P18031,Q96HE7 9 +Coenzyme a biosynthetic process 0.4003730226494447 0.3296494823387592 0.7416648290507684 1.0 0.9651968987401072 6 P35610,Q8WVC6 2 +Binding of sperm to zona pellucida 0.3428470146171404 0.3270272842942027 0.7436472489288468 1.0 0.966391722386373 12 P45880 1 +Sperm egg recognition 0.3428470146171404 0.3270272842942027 0.7436472489288468 1.0 0.966391722386373 12 P45880 1 +Negative regulation of cysteine type endopeptidase activity 0.309237326455834 0.326228251165346 0.7442516682407463 1.0 0.9667818523070064 20 P51812,Q96K76,P16435,Q15418,Q15392 5 +Sequestering of metal ion 0.5882616526264305 0.3254346229586251 0.7448521550405629 1.0 0.9671457003678056 3 O14617 1 +Cellular response to molecule of bacterial origin 0.2959895267980527 0.3250327904209682 0.7451562547344888 1.0 0.9671457003678056 25 Q8WTV0,P08670,Q9NUQ9,Q86UE4 4 +Regulation of vasoconstriction 0.5870463783674293 0.3220458758574546 0.7474179403900074 1.0 0.9697057418083052 3 P42892 1 +Neutrophil migration 0.3275181325954568 0.3217183522134875 0.7476660733777829 1.0 0.9697404520187944 14 Q8N5M9,Q07021,P35613,O00429,Q8NHP6 5 +Mitochondrion distribution 0.4196181446497755 0.3206850322088746 0.7484490912702306 1.0 0.9704492909248442 5 O75153,O00429 2 +Reactive oxygen species biosynthetic process 0.3625226827629918 0.319572709056275 0.7492922653117413 1.0 0.9709483462429008 10 Q15067,Q9BSK2 2 +Negative regulation of cell aging 0.5052700922266011 0.3191155501963023 0.7496388923028809 1.0 0.9710047810959728 4 P14174,P67809,Q9NX47 3 +Positive regulation of nf kappab transcription factor activity 0.3009792620580935 0.3191123006820066 0.7496413563307014 1.0 0.9710047810959728 23 Q96HY6,Q86UE4,P05067 3 +Fc receptor signaling pathway 0.3972678657494317 0.3167206786214758 0.7514555567096433 1.0 0.972132307930236 6 Q08722 1 +Regulation of the force of heart contraction 0.4178189399913976 0.3140228108408058 0.7535037138966947 1.0 0.9736266732115046 5 P16615,P10253 2 +Body morphogenesis 0.3885152254936915 0.3134160832973428 0.7539645666203669 1.0 0.9738211225964492 8 O95470,O75122 2 +Axonal transport of mitochondrion 0.417140319587975 0.3115209512197176 0.7554046179510228 1.0 0.974695848903106 5 Q9UH62 1 +Positive regulation of transmembrane transport 0.2889663044597556 0.3108011671141155 0.7559517823693471 1.0 0.9748766866557476 29 P0DP25,Q96GC9 2 +Cellular response to mineralocorticoid stimulus 0.582728364015146 0.310126128028324 0.7564650438304197 1.0 0.9748766866557476 3 P20020 1 +Locomotor rhythm 0.582369805087344 0.3091448996616609 0.7572113058397694 1.0 0.9755816673742548 3 P54802 1 +Cellular modified amino acid metabolic process 0.2720147619570303 0.3089164327093592 0.7573850962857651 1.0 0.9755816673742548 54 Q9UJ14,Q92820,P78417,P23786,Q9UHG3,O60725,P16435,Q9NVH6,Q9H2D1,P00374,O43708 11 +Synaptic vesicle priming 0.5019249858797727 0.3085997119714371 0.7576260399873067 1.0 0.9755816673742548 4 Q7L0J3 1 +Regulation of protein targeting to membrane 0.387229115243546 0.3075814653912548 0.7584008253896724 1.0 0.975723710929833 8 P27105 1 +Cell cell adhesion via plasma membrane adhesion molecules 0.3389711906292911 0.3047883358939829 0.7605273657322871 1.0 0.977732996883984 12 P35613,P98194,Q9Y639 3 +Copii coated vesicle cargo loading 0.3869302839623273 0.3033529976582155 0.7616208614117943 1.0 0.9784009836299964 7 Q9NR31 1 +L serine catabolic process 0.5757077024358063 0.3023579050934096 0.7623792407149717 1.0 0.9784009836299964 2 P34896 1 +Mitochondrial outer membrane permeabilization involved in programmed cell death 0.3731485206447789 0.3020862786667642 0.7625862921496227 1.0 0.9784009836299964 9 P45880 1 +Response to mineralocorticoid 0.3865411515534958 0.3016599252853765 0.7629113208514657 1.0 0.9786204551628488 7 P20020,P0DP25,O95831 3 +Regulation of intracellular estrogen receptor signaling pathway 0.3271662615685265 0.3013733380647597 0.7631298229086325 1.0 0.9787032192105062 13 Q99623,Q96HY6,Q9NUQ7,Q92600,A5YKK6,Q9P253 6 +Positive regulation of small molecule metabolic process 0.3240039487427633 0.300085370993803 0.7641120375423962 1.0 0.979164997901452 14 P50416,P16435,P04083,P05067,Q92604 5 +Regulation of plasma membrane organization 0.4988413846800501 0.2990168021681834 0.7649272254623598 1.0 0.9795815119869922 4 Q05655 1 +Escrt complex disassembly 0.3857566765578595 0.2982531351182193 0.7655099701131829 1.0 0.9795815119869922 7 Q9HD42,O43633,Q9NZZ3,Q9NP79,P53990,Q8WUX9 6 +Histone h4 deacetylation 0.4983411957789865 0.2974725298862254 0.7661057772674129 1.0 0.9796891596873109 4 Q8IXJ6 1 +Regulation of cellular response to osmotic stress 0.577882962619428 0.2969788585794433 0.7664826497946704 1.0 0.9796891596873109 3 O95202 1 +Positive regulation of receptor internalization 0.5777105222661281 0.296515480814941 0.7668364462721056 1.0 0.9798979598925418 3 Q06787 1 +Neuron projection guidance 0.3003875243099495 0.2956152960412341 0.7675238909142692 1.0 0.9801154260362944 22 P42892,P05067,O00264 3 +Oligodendrocyte differentiation 0.3083138982454088 0.2928049193209283 0.769671267901836 1.0 0.980963970640576 18 Q92542,Q15382,Q9NR50 3 +Serine family amino acid catabolic process 0.5758972670398336 0.291661914810216 0.7705451312600444 1.0 0.9814799307192068 3 P34896,P23378 2 +Negative regulation of intracellular steroid hormone receptor signaling pathway 0.370760009405081 0.2905731121912558 0.7713778265322113 1.0 0.9817535974046326 9 Q99623,Q9P253,Q92600 3 +Sphingomyelin biosynthetic process 0.4946991118341677 0.2863148241008475 0.7746370051832416 1.0 0.982584520622195 4 O15269 1 +Regulation of meiotic cell cycle 0.4938904013796377 0.283858205114755 0.776519047008267 1.0 0.983259149853002 4 Q8IXJ6 1 +Lens development in camera type eye 0.4937482419181829 0.2834271595185677 0.7768494112903563 1.0 0.983259149853002 4 P08670 1 +Negative regulation of translational initiation 0.3816927045805502 0.2827170018365088 0.7773937821595314 1.0 0.983259149853002 8 P60228,Q9BPZ3,Q9BWF3 3 +Histone h3 acetylation 0.3451070660527421 0.2803633276476243 0.7791987695294114 1.0 0.9846021130416932 11 Q9Y6J9 1 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.5707740646313952 0.278137745258272 0.7809066218963334 1.0 0.985834617701119 3 P04439 1 +L phenylalanine metabolic process 0.570357087631864 0.2770494403571535 0.7817421434362548 1.0 0.9862611737921094 3 O43708 1 +Aromatic amino acid family catabolic process 0.570357087631864 0.2770494403571535 0.7817421434362548 1.0 0.9862611737921094 3 O43708 1 +Positive regulation of membrane permeability 0.3543250582074572 0.277043143787264 0.7817469782197368 1.0 0.9862611737921094 10 P45880 1 +Potassium ion import across plasma membrane 0.4908363171032843 0.2746503250198533 0.7835848987539722 1.0 0.987599765314346 4 P05023,P55011 2 +Positive regulation of phagocytosis 0.4067817716781828 0.274105129116314 0.7840038322779972 1.0 0.9876085254133408 5 Q08722 1 +Positive regulation of muscle contraction 0.3865268927486522 0.2730238191285221 0.784834905894082 1.0 0.9876085254133408 6 P78417 1 +Chromosome organization involved in meiotic cell cycle 0.3052500774488255 0.2721891354859576 0.7854765952110678 1.0 0.988024785110142 18 Q9BXW9,Q15645,Q9BTX1,O60566,O94901,Q92791 6 +Negative regulation of neuron death 0.2731558485956366 0.2719608351188136 0.7856521337139051 1.0 0.9880500518174872 38 P09601,P50897,P04062,O76024 4 +Positive regulation of viral life cycle 0.3795564964546531 0.2716349017339417 0.7859027604242153 1.0 0.9881697221080736 7 Q9H9H4,P07237,P52292 3 +Response to heat 0.2801991681885905 0.2706117253954947 0.786689676658733 1.0 0.9887515481378788 33 P09601 1 +Non lytic viral release 0.3856295319710019 0.2694485344071233 0.7875845416141061 1.0 0.9891103233549216 6 Q9HD42,O43633,Q9NZZ3,Q9H444,Q8WUX9 5 +Isoprenoid biosynthetic process 0.352643231561293 0.2684475488813375 0.7883548434275265 1.0 0.9896038046178364 10 Q5T2R2,Q86SQ9 2 +Inositol lipid mediated signaling 0.3122672416621895 0.2681958072673915 0.7885486021339199 1.0 0.9896038046178364 16 Q07021,Q8NEB9,Q10713 3 +Inorganic ion import across plasma membrane 0.404506606532519 0.266088157274432 0.7901713154514114 1.0 0.991379565931538 5 P05023,P55011 2 +Cellular response to dsrna 0.3654393813338759 0.2652284382983844 0.7908334885612311 1.0 0.991818795046406 9 Q9NUD5,Q08211,Q7Z434,Q5KU26 4 +Process utilizing autophagic mechanism 0.2959412002441819 0.2643946321451035 0.7914758473387287 1.0 0.99214885293769 161 Q86Y82,P07602,P09601,Q9NZJ7,P05141,Q86UE4,Q9Y6I9,Q9NZ45,P52789,P12235,Q9UEU0,O15269,P04062,Q15382,O75844,Q676U5,P56962,Q8IXJ6,Q07820,Q96GC9,P16615,Q93050,P10619,Q9BWH2,P21796,O00429,Q9Y487,Q9P253,Q96HY6,Q969Q5,Q8NEB9,Q9BXS4,Q9H0U4,O15118 34 +Response to ether 0.4873830318965444 0.2643730962993535 0.7914924402906893 1.0 0.99214885293769 4 Q9H4A6,Q14103 2 +Regulation of anaphase promoting complex dependent catabolic process 0.5602369980250181 0.2618679078139578 0.7934232822961489 1.0 0.9926536678003868 2 P53350 1 +Neuroblast proliferation 0.3414298631386557 0.2607331223496473 0.7942983213441008 1.0 0.993140562958504 11 Q8NCG7 1 +T cell activation 0.26742291567748 0.2583095074756025 0.7961680492920182 1.0 0.9934234981313104 54 P24390,Q08722,Q9NUQ9,O96005,P62942 5 +Positive regulation of intracellular transport 0.2633574998243215 0.2567641451808563 0.7973608502932126 1.0 0.9935319509924828 64 O43464,Q08211,Q9GZY8,Q9Y282,Q92544,Q9Y6B6,P51572,Q9P2W9,Q15154,Q9C0E2,O14737,P27105,P50402,Q05655,Q9Y371,P55786,Q9NR31 17 +Glandular epithelial cell differentiation 0.3754652320762933 0.2543812323793715 0.799201048583231 1.0 0.9935319509924828 7 Q15382,Q86UL3 2 +Negative regulation of fat cell differentiation 0.4011027937034399 0.2542348699589952 0.7993141130582329 1.0 0.9935319509924828 5 Q8IXJ6,Q8N4Q0 2 +Negative regulation of dna binding transcription factor activity 0.2921899893789053 0.253649358654303 0.7997664606198107 1.0 0.9935319509924828 23 P09601,O75381 2 +Vascular transport 0.3496775594218765 0.2534042694714949 0.7999558287459629 1.0 0.9935319509924828 10 P02786,Q15758,P08183,P11166,Q99808,P55011 6 +Regulation of wound healing 0.3295065980912991 0.2515939101950287 0.8013549662037687 1.0 0.9935319509924828 12 O75122,Q05655,P42345,P04083,P55011 5 +Chondroitin sulfate proteoglycan biosynthetic process 0.5598874576918242 0.250350246143094 0.8023165024645813 1.0 0.9935319509924828 3 Q96L58 1 +Chondroitin sulfate biosynthetic process 0.5598874576918242 0.250350246143094 0.8023165024645813 1.0 0.9935319509924828 3 Q96L58 1 +Lung associated mesenchyme development 0.5552995391705087 0.2496086079939664 0.8028900410549167 1.0 0.9935319509924828 2 P35222 1 +Protein localization to cell surface 0.3057202743147912 0.2495644383905031 0.8029242025378391 1.0 0.9935319509924828 17 Q15907,Q92643,Q9HD47,Q13277,Q96PU5 5 +Head morphogenesis 0.3995775932917196 0.2489792376098979 0.8033768417705545 1.0 0.9935319509924828 5 O95470 1 +Lymph vessel development 0.5549703752468749 0.2488029661460184 0.8035131965922084 1.0 0.9935319509924828 2 P24468 1 +Germ cell migration 0.5549703752468749 0.2488029661460184 0.8035131965922084 1.0 0.9935319509924828 2 P05556 1 +Regulation of core promoter binding 0.5549703752468746 0.2488029661460178 0.8035131965922089 1.0 0.9935319509924828 2 P35222 1 +Regulation of alternative mrna splicing via spliceosome 0.2764901058674724 0.2487099498402938 0.8035851517824473 1.0 0.9935319509924828 34 Q9UHX1,P09651,P98175,P51114,Q9BWF3,Q07666,P62995,Q06787,P38159,Q15287,Q96T37,O75525 12 +Glial cell differentiation 0.2671303051494268 0.2481252594279496 0.8040374924016447 1.0 0.9935319509924828 40 P08670,Q8IXJ6,Q9NR50,P04062,Q15382,Q92542,P05067 7 +Primary alcohol metabolic process 0.3054880156709413 0.2480711575707737 0.80407935114936 1.0 0.9935319509924828 17 Q9Y394,Q6NUM9,Q06520,Q9HBH5,Q8NBN7,P51648 6 +Toxin transport 0.3379972905291021 0.2426269802145343 0.8082943784417056 1.0 0.9959876376267528 11 Q93050 1 +Negative regulation of glycoprotein metabolic process 0.5567005521610641 0.2424666249235997 0.808418614828057 1.0 0.9959876376267528 3 Q9BXS4 1 +Leukocyte mediated immunity 0.2652760580044854 0.2420572779413148 0.8087357811712095 1.0 0.9959876376267528 43 P11279,Q8N5M9,P09601,Q07021,Q05655,Q9NUQ9 6 +Rna interference 0.3603699540031287 0.2414883741421413 0.8091766259926885 1.0 0.9959876376267528 9 O75569,Q9HAV4,Q08211,Q15631 4 +Microtubule anchoring 0.3276279469292513 0.241237276686835 0.809371221244567 1.0 0.9959876376267528 12 O75381,O95684,O75122 3 +Response to hydrogen peroxide 0.2926091379034754 0.2393809944848199 0.8108101658659324 1.0 0.9966888899600886 22 Q99720,P09601,Q05655 3 +Negative regulation of microtubule polymerization 0.3964667925784614 0.2383686185611531 0.8115952047633748 1.0 0.9969718733335684 5 Q9BTW9 1 +Zinc ion transport 0.5503620803159992 0.2376781459614154 0.8121307350005764 1.0 0.9972764589767512 2 Q8NEW0 1 +Intra golgi vesicle mediated transport 0.3036365072976991 0.2362138483419105 0.8132667341222652 1.0 0.9973459974297116 17 O14653,Q8TBA6,Q9UEU0,O95249,O14579 5 +Immune response regulating signaling pathway 0.2652674921576904 0.2321456317546899 0.816424903783681 1.0 0.999075219185421 52 Q99623,P51812,O43657,Q9NQC3,P49770,Q9NR50,Q9NUD5,Q9NPR9,P46379,Q07666,Q07021,Q9UJZ1,P04439,Q08722,Q05655 15 +Action potential 0.2952742565258577 0.2288811683120439 0.8189612775914428 1.0 1.0 20 Q9HD47,P0DP25,P16615,P05023,P04062 5 +Nucleoside metabolic process 0.2984955340610945 0.2275303043565764 0.8200114076281706 1.0 1.0 18 O60725 1 +Trna transport 0.3924528083136711 0.2248972655165815 0.8220591966120572 1.0 1.0 5 P67809,O43592 2 +Regulation of gliogenesis 0.3243475378730714 0.2233247375518782 0.823282775613702 1.0 1.0 12 Q15382,Q96G23 2 +Rrna pseudouridine synthesis 0.3918320309299541 0.2228363741523017 0.8236628572152942 1.0 1.0 5 Q8IZ73 1 +Negative regulation of binding 0.2708234732172159 0.2218041634049405 0.8244663382583617 1.0 1.0 36 P09601,Q05655,P40855,O75381 4 +Response to catecholamine 0.3135263246820362 0.2216268848926309 0.8246043517948793 1.0 1.0 13 Q92542,P05067 2 +Positive regulation of mitotic nuclear division 0.3430428265261603 0.2203019084595476 0.8256360339376303 1.0 1.0 10 Q9UJX3,Q9UJX2 2 +Positive regulation of protein catabolic process 0.2612416387388596 0.2189916302119306 0.8266565676573281 1.0 1.0 62 Q9P0J0,Q6ZXV5,P48729,Q8IXJ6,O14965,Q96HY6,Q9UHD9,Q9UBS8,P46379,P51572,O75396,Q9Y5A7,Q96PU5,P04062,P53634,Q8NF37,Q13190 17 +Fc gamma receptor signaling pathway 0.4705690607835208 0.2164539904729914 0.8286338852856789 1.0 1.0 4 Q08722 1 +Positive regulation of anion transmembrane transport 0.4699370103472183 0.2147236682088644 0.8299827684005849 1.0 1.0 4 Q15041 1 +Regulation of cell activation 0.2623774735252047 0.2135403453448829 0.8309055236953728 1.0 1.0 58 P09601,Q08722,Q05655,Q9BWH2,Q9NUQ9,O96005 6 +Peptidyl arginine methylation to asymmetrical dimethyl arginine 0.54395785314454 0.2121150204102005 0.8320173017306136 1.0 1.0 3 O60678,Q86X55 2 +Regulation of protein localization to plasma membrane 0.2773326683393847 0.2102232052056569 0.8334934690822549 1.0 1.0 28 O15258,Q9HD47,Q9BXS4,O00264,Q13277,Q9UEU0,O15400 7 +Multicellular organism reproduction 0.2619083956562869 0.2064473250553546 0.8364415068797899 1.0 1.0 108 O75718,Q9BQE5,Q9Y5A9,P35613,Q9BPZ3,Q15645,P41208,Q8IZL8,Q9H8Y8,Q9BXW9,O95470,P51572,P46379,Q8NB78,O94901,P15291,Q01085,Q96PU8,Q8IXJ6,Q07666,Q15363,Q15067,Q96EP5,O14965,Q9BTX1,P04083,Q9H2V7,P05067 28 +Rna stabilization 0.2773321978360353 0.2061605459032245 0.8366655056142132 1.0 1.0 27 O60506,Q13151,Q14103,P67809,P98175,Q08211,P07910,Q14011,Q92804,P35637 10 +Regulation of receptor localization to synapse 0.4667180569942134 0.2059936929337657 0.8367958379684299 1.0 1.0 4 O15400 1 +Reactive oxygen species metabolic process 0.2675980791261447 0.2056034718135972 0.8371006653536415 1.0 1.0 37 Q9P0J0,Q9BSK2,Q8IXJ6,P52789,Q15067,Q05655,P00374,Q13423 8 +Response to steroid hormone 0.2600666566390389 0.2053804092894889 0.8372749251530822 1.0 1.0 62 Q96HY6,P16278,Q9UBS8,P0DP25,P16435,Q92600,O15173,P04062,P04083,Q9P253,O15118 11 +Protein peptidyl prolyl isomerization 0.2876806584673707 0.2045928550357025 0.8378902381798548 1.0 1.0 22 Q9Y680,P62942,O95302 3 +Regulation of neuronal synaptic plasticity 0.3397701472420443 0.2042699360856857 0.8381425621628145 1.0 1.0 10 Q9Y639,P05067 2 +Retina development in camera type eye 0.304981414575025 0.2036682553654266 0.8386127507560817 1.0 1.0 15 Q15555,P54802,Q8NF37,Q8NBN7 4 +Positive regulation of inflammatory response 0.3202391330879724 0.2012119943878185 0.8405328131264407 1.0 1.0 12 Q08722,Q08211,P05067 3 +Lipophagy 0.3851695575794624 0.2011065360451923 0.8406152713793755 1.0 1.0 5 O15269 1 +Epithelial cell apoptotic process 0.32011134726692 0.2005301253558372 0.8410659998250245 1.0 1.0 12 P09601 1 +Positive regulation of oligodendrocyte differentiation 0.3847931807933422 0.1999005203904486 0.8415583834446667 1.0 1.0 5 Q15382 1 +Regulation of dna dependent dna replication initiation 0.5383602239051586 0.1993873153059118 0.8419597821977987 1.0 1.0 3 P24941,O95251 2 +Phosphatidylinositol dephosphorylation 0.4640812222308949 0.1989459521133017 0.8423050233166298 1.0 1.0 4 Q10713 1 +Phospholipid dephosphorylation 0.4640812222308949 0.1989459521133017 0.8423050233166298 1.0 1.0 4 Q10713 1 +Carbohydrate derivative biosynthetic process 0.2908444071354024 0.1981743717436798 0.8429086382059694 1.0 1.0 160 Q86YN1,Q5H8A4,O43505,Q96L58,Q86SQ9,Q8NBX0,Q13126,O43909,Q9BV10,P00846,Q9UIJ7,P50897,Q9BT22,Q9NZ01,P31350,Q9H0U3,Q99805,P24539,Q8NCH0,P15291,Q8WVC6,Q6ZXV5,Q53GQ0,P35610,O75964,Q9UKU0,Q10471,P56385,Q9H4A6,Q9NRB3,Q9UMR5,Q92542,P46977,Q7LGA3,Q9HC07,Q92643,P56134,P04844,Q9UJS0,Q9BXS4,O60762,Q10472,P06865,Q8TB61,O15118 45 +Collagen fibril organization 0.3508579566557652 0.1981028812145097 0.8429645706256896 1.0 1.0 9 Q92791,P13674 2 +Respiratory gaseous exchange by respiratory system 0.3381957751437537 0.1966304636753019 0.8441167294179539 1.0 1.0 10 Q7KZN9 1 +Regulation of axon guidance 0.4627799736495388 0.1955026547165766 0.8449994596169026 1.0 1.0 4 Q9BYJ9,O94813,Q9UNW9 3 +Galactose metabolic process 0.5358571962424066 0.1938178220917828 0.8463185316125525 1.0 1.0 3 P16278 1 +Endosome organization 0.2739035967418364 0.1933241405545006 0.8467051215055432 1.0 1.0 30 Q9BTU6,Q8WUM4,Q8NEB9,O43752,Q14108,Q9H9H4,P51790,Q9P253 8 +Gland development 0.2559198676312558 0.1906138757152995 0.848828118271296 1.0 1.0 67 Q13505,Q5T9L3,Q14103,P50416,Q9UNS2,Q9UGP8,Q9NQC3,O14965,P07602,P09601,Q9NZJ7,P52789,P35610,Q15418,P04083,O75844,Q99808 17 +Plasma membrane to endosome transport 0.5341423489829529 0.190045909017576 0.8492731558328857 1.0 1.0 3 Q99523 1 +Regulation of meiotic nuclear division 0.5340068871904253 0.1897494751658663 0.8495054494525671 1.0 1.0 3 Q8IXJ6 1 +Lymphocyte migration 0.3274946763046054 0.1886406883378547 0.8503744406166938 1.0 1.0 11 P05067 1 +Glycolytic process through fructose 6 phosphate 0.3592401139360497 0.1865534165408292 0.8520107936380854 1.0 1.0 8 Q9BRR6 1 +Insulin metabolic process 0.5322098024206048 0.1858380333689774 0.8525717777065223 1.0 1.0 3 Q96HE7 1 +Positive regulation of immune effector process 0.2735452989763779 0.1850028859553227 0.8532267719836781 1.0 1.0 29 Q99623,P11279,P09601,P04439,P04083,Q9NUQ9,O15400 7 +Positive regulation of cellular protein catabolic process 0.259953062043644 0.1834528995183917 0.8544426722628788 1.0 1.0 45 Q6ZXV5,P48729,Q8IXJ6,O14965,Q96HY6,Q9UHD9,Q9UBS8,P46379,P51572,Q9Y5A7,P04062,P53634 12 +Negative regulation of neuron projection development 0.2899161378966075 0.1818795192842502 0.855677277651876 1.0 1.0 19 Q9NQC3,Q96G23 2 +Striated muscle cell proliferation 0.4571805006587613 0.1809504003474525 0.8564065080114773 1.0 1.0 4 Q12948,P10644,P06493 3 +Granulocyte chemotaxis 0.3003810737366182 0.1767042945280426 0.8597406674166299 1.0 1.0 15 Q07021,P35613,O00429,Q8NHP6,P04083 5 +Amyloid precursor protein biosynthetic process 0.4552664368506839 0.1760756401685376 0.8602345182519682 1.0 1.0 4 Q92542 1 +Sertoli cell development 0.5268356931182074 0.1743769804525078 0.8615692040924561 1.0 1.0 3 P51153,Q9Y2H6 2 +Regulation of toll like receptor 3 signaling pathway 0.5255186038854028 0.1716223562317528 0.8637344305002423 1.0 1.0 3 P41440,O75955 2 +Protein localization to membrane raft 0.5255186038854028 0.1716223562317528 0.8637344305002423 1.0 1.0 3 P41440,O75955 2 +Developmental maturation 0.2620262063823834 0.1684288220641623 0.8662459352546974 1.0 1.0 38 Q8IXJ6,O14965,Q86UL3,Q15125,Q9NZJ7,Q9Y5A9,Q15645,P51790,P04062,O14617,P05067,O75503 12 +Cytoplasm organization 0.5181040157998702 0.1680632034373255 0.866533556952823 1.0 1.0 2 Q9Y2W6 1 +Eye morphogenesis 0.3319330821056946 0.1667309021453727 0.8675817894717832 1.0 1.0 10 P54802,Q8NBN7 2 +Maintenance of protein location 0.2721842085368128 0.1666130773806902 0.8676745032734086 1.0 1.0 27 O15258,O43731,P52789,P24390 4 +Cellular response to carbohydrate stimulus 0.2815961215237128 0.1626519860339141 0.8707924530283311 1.0 1.0 22 Q15907,Q15120,O95563,Q8N5M9,Q96RR1,P62995,Q8N183,P63244,Q6ZWJ1,Q5KU26,P54646,Q9NWS0,Q99808 13 +Aging 0.2563106196596956 0.1622238483895889 0.8711295802408074 1.0 1.0 62 O43464,P67809,P04844,Q9UGP8,P20020,O60313,Q6PHR2,P27824,Q05655,P04062,P00846,Q96HE7,P05067,O75844,P55011 15 +Regulation of leukocyte mediated immunity 0.2718778286805157 0.1618129621192432 0.871453145272933 1.0 1.0 26 Q9NUQ9,P09601 2 +Toll like receptor signaling pathway 0.3003927008208872 0.1615775830895141 0.8716385114254461 1.0 1.0 14 Q9NQC3 1 +T helper 1 type immune response 0.5204038820754922 0.1611291096261501 0.8719917136264166 1.0 1.0 3 P04083 1 +T helper 1 cell differentiation 0.5204038820754922 0.1611291096261501 0.8719917136264166 1.0 1.0 3 P04083 1 +Peptidyl threonine modification 0.2697725322808496 0.1602746081184682 0.8726647600726285 1.0 1.0 30 Q10472,P0DP25,P05067 3 +Positive regulation of protein glycosylation 0.5134957208689948 0.1593195398397472 0.8734171268130959 1.0 1.0 2 Q08379 1 +Regulation of sodium proton antiporter activity 0.5134957208689948 0.1593195398397472 0.8734171268130959 1.0 1.0 2 O43707 1 +Oogenesis 0.3022660154536531 0.1589596130716773 0.8737006932747757 1.0 1.0 13 Q15645,Q8IXJ6,Q9Y5A9 3 +Extrinsic apoptotic signaling pathway via death domain receptors 0.297187336131047 0.1583172116634184 0.8742068462329391 1.0 1.0 15 P09601 1 +Cardiac ventricle development 0.2997412545161896 0.1579491731504655 0.8744968497863477 1.0 1.0 14 O75844 1 +Organelle transport along microtubule 0.2679250604392484 0.157876472952003 0.8745541374056136 1.0 1.0 32 Q9UH62,P11279,O60313,O94901,Q9Y2T2,O75381 6 +Phosphatidylinositol phosphate biosynthetic process 0.3212004380048166 0.1573958579394166 0.87493287765702 1.0 1.0 11 Q8NEB9,Q9NX62 2 +Regulation of rig i signaling pathway 0.3554735638340873 0.1569311515386181 0.8752991086508515 1.0 1.0 6 Q9NUD5 1 +Plus end directed organelle transport along microtubule 0.5182746131050224 0.1568567909181784 0.875357714077345 1.0 1.0 3 Q9Y496,Q92845 2 +Insulin like growth factor receptor signaling pathway 0.5169575238722369 0.1542424649061681 0.8774185606401432 1.0 1.0 3 Q6Y7W6,P11717 2 +Meiosis i cell cycle process 0.2869115747892158 0.1537940987544905 0.8777720869909194 1.0 1.0 18 O14965,Q9BXW9,Q15645,Q9BTX1,O94901,Q92791 6 +Epithelial cell proliferation 0.2566589207787606 0.1537371195849275 0.8778170154969156 1.0 1.0 44 P57105,P09601 2 +Cellular response to interferon beta 0.351072111207192 0.1536681294746357 0.8778714152472271 1.0 1.0 8 Q9P0J0,P49427,O43464 3 +Response to interferon beta 0.351072111207192 0.1536681294746357 0.8778714152472271 1.0 1.0 8 Q9P0J0,P49427,O43464 3 +Cellular response to acid chemical 0.3109234339320813 0.1524926926735401 0.8787983534392949 1.0 1.0 12 Q14103,Q99729,O00410,P42345,Q9UQB8,Q9P2J5 6 +Positive regulation of metaphase anaphase transition of cell cycle 0.3494020006290396 0.1509799627499349 0.8799915221050176 1.0 1.0 7 Q9UJX2 1 +Regulation of nervous system process 0.2984240556352671 0.1506481198756026 0.8802533003604651 1.0 1.0 14 P05067 1 +Lung alveolus development 0.514981890023046 0.1503617351563406 0.8804792289235011 1.0 1.0 3 P00813,O60476 2 +Vesicle fusion to plasma membrane 0.4447561448570961 0.1502311389221567 0.8805822593676544 1.0 1.0 4 Q13277 1 +T cell differentiation involved in immune response 0.4446203041111958 0.1499074680199917 0.8808376196731753 1.0 1.0 4 P04083 1 +Cd4 positive alpha beta t cell differentiation 0.4446203041111958 0.1499074680199917 0.8808376196731753 1.0 1.0 4 P04083 1 +Purine containing compound biosynthetic process 0.2449906523038103 0.1497750498563647 0.8809420946165996 1.0 1.0 76 Q53GQ0,P24539,Q9UKU0,O75964,Q8TB61,Q13126,P00846,Q9UIJ7,P50897,Q9UMR5,Q8WVC6 11 +Glomerular epithelium development 0.368369028006589 0.1496178874813296 0.8810660948734244 1.0 1.0 5 P80723,Q12948,P11047,Q04721 4 +Paraxial mesoderm morphogenesis 0.5065832784726814 0.1467712572542257 0.8833125723416642 1.0 1.0 2 Q12948 1 +Paraxial mesoderm formation 0.5065832784726814 0.1467712572542257 0.8833125723416642 1.0 1.0 2 Q12948 1 +Very long chain fatty acid catabolic process 0.512612840577171 0.1457728487909797 0.8841007104385434 1.0 1.0 3 Q15067 1 +Neutrophil chemotaxis 0.3092688498612534 0.1440587528470826 0.8854540753632503 1.0 1.0 12 Q07021,P35613,O00429,Q8NHP6 4 +Positive regulation of ubiquitin protein ligase activity 0.5113598946328491 0.1433744220381333 0.885994482514372 1.0 1.0 3 P53350,P63208 2 +Meiotic sister chromatid cohesion centromeric 0.5111038900530553 0.1428868035000644 0.8863795809071866 1.0 1.0 3 O60566 1 +Meiosis ii cell cycle process 0.5111038900530553 0.1428868035000644 0.8863795809071866 1.0 1.0 3 O60566 1 +Tripartite regional subdivision 0.5107013500164617 0.1421217456968741 0.8869838419411566 1.0 1.0 3 Q9Y2W6,Q9UK61 2 +Blastoderm segmentation 0.5107013500164617 0.1421217456968741 0.8869838419411566 1.0 1.0 3 Q9Y2W6,Q9UK61 2 +Metanephros morphogenesis 0.5107013500164612 0.142121745696873 0.8869838419411575 1.0 1.0 3 P42224,P35222 2 +Regulation of monocyte chemotaxis 0.4406951349898518 0.1406706056020775 0.888130167478415 1.0 1.0 4 Q99538 1 +Motor neuron apoptotic process 0.5029624753127078 0.1404695343586598 0.888289021863184 1.0 1.0 2 P49327 1 +Positive regulation of monocyte chemotaxis 0.5096608941975954 0.1401537467509262 0.8885385158528103 1.0 1.0 3 Q99538 1 +Regulation of signaling receptor activity 0.2939815751789679 0.1401485792064749 0.8885425986612216 1.0 1.0 15 P05067 1 +Response to thyroxine 0.500987491770904 0.1371106015589278 0.8909433727805158 1.0 1.0 2 O94826 1 +Response to l phenylalanine derivative 0.500987491770904 0.1371106015589278 0.8909433727805158 1.0 1.0 2 O94826 1 +Centriole centriole cohesion 0.439064558629777 0.1368995568245965 0.8911101891413626 1.0 1.0 4 Q9Y496,P35222,Q9C0F1 3 +Response to xenobiotic stimulus 0.2540189906333999 0.1361796403477544 0.8916792698665326 1.0 1.0 62 O43169,P04844,P09601,P78417,P07099,P16435,Q9UHB9,Q16836 8 +Neural precursor cell proliferation 0.2684016305463909 0.1361246770201049 0.891722719661588 1.0 1.0 26 Q8NCG7,Q8IXJ6,P61026,P55209 4 +Chondrocyte differentiation 0.346444227336861 0.1355875851886556 0.8921473203962669 1.0 1.0 8 Q9NX62,P16435 2 +Regulation of erbb signaling pathway 0.3074930106604179 0.1350840119502571 0.8925454509229318 1.0 1.0 12 Q9NQC3 1 +Negative regulation of epidermal growth factor activated receptor activity 0.5064208100098699 0.1341127465661212 0.8933134203992572 1.0 1.0 3 Q9BRG1,Q9UNH7 2 +Pyridine containing compound biosynthetic process 0.3621331338679139 0.1317744072720429 0.895162730036263 1.0 1.0 5 Q9BQG2 1 +Regulation of golgi to plasma membrane protein transport 0.3621087314662328 0.1317059771853072 0.8952168575972042 1.0 1.0 5 P63244,O75608,P98194,O95573 4 +Protein hydroxylation 0.2827561706360166 0.1283285451309183 0.8978889761132953 1.0 1.0 18 O75718,Q96AY3,Q96HE7,P07237,O15460,Q92791,P13674 7 +Regulation of perk mediated unfolded protein response 0.5031521536758858 0.1281529759965356 0.8980279128493462 1.0 1.0 3 P57088 1 +Positive regulation of phospholipid metabolic process 0.3603731936631799 0.126867314765452 0.8990454165992454 1.0 1.0 5 Q05655 1 +Axoneme assembly 0.5019573920425956 0.1260083116912428 0.8997253452433989 1.0 1.0 3 Q15555 1 +Negative regulation of cellular amide metabolic process 0.2417694110118459 0.1240888487385021 0.9012449273350218 1.0 1.0 87 O60506,Q7Z739,Q9Y5A9,Q92600,Q5PRF9,Q10713,Q9BPZ3,O95197,Q14103,Q9HCE1,P60228,Q14011,Q9NQC3,Q9BWF3,P49458,P00374,P67809,Q08211,Q92945,Q16799,Q969T7,Q14671,Q9HBH5,Q06787,A5YKK6 25 +Calcium ion regulated exocytosis 0.3336344387561009 0.1238487157776454 0.901435059091886 1.0 1.0 9 P16615,Q9BRK5 2 +Cellular response to potassium ion 0.5003413305498879 0.1231361628113211 0.9019992753888996 1.0 1.0 3 P55011 1 +Response to potassium ion 0.5003413305498879 0.1231361628113211 0.9019992753888996 1.0 1.0 3 P55011 1 +Water homeostasis 0.3431017509311768 0.1227883726270601 0.9022746818816992 1.0 1.0 8 P04062,O76024 2 +Response to cadmium ion 0.2953012168654618 0.1218483914410862 0.9030190886209122 1.0 1.0 13 P09601 1 +Apoptotic process involved in development 0.3434410019775906 0.1166423117492756 0.9071435066307694 1.0 1.0 6 O75312,Q14160,Q12948,O94813,P30154 5 +Pyrimidine containing compound metabolic process 0.265150779253791 0.1165831275279139 0.9071904088202944 1.0 1.0 28 Q9H773,Q9UIJ7 2 +Regulation of synaptic plasticity 0.264997883704298 0.1154438494880086 0.9080933244102364 1.0 1.0 28 Q99538,Q13277,Q9Y639,Q06787,Q9BPZ3,Q15042,Q92542,P05067,Q14168 9 +Positive regulation of stress activated protein kinase signaling cascade 0.3120342392769892 0.1135357420766881 0.9096058281865478 1.0 1.0 11 P05067 1 +Positive regulation of vacuole organization 0.354730313793291 0.1115228477458047 0.9112017487276192 1.0 1.0 5 Q9Y371 1 +Negative regulation of endocytosis 0.29115813237208 0.1112598999093107 0.9114102531596192 1.0 1.0 14 P05067 1 +Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.4925913730655256 0.1098224718168851 0.9125501689085256 1.0 1.0 3 Q9BRG1,Q9H3S7 2 +Histone h4 r3 methylation 0.4822251481237678 0.1079323159254993 0.9140493824496498 1.0 1.0 2 Q99873 1 +Positive regulation of g protein coupled receptor signaling pathway 0.4822251481237677 0.1079323159254993 0.9140493824496498 1.0 1.0 2 P35232 1 +Paraxial mesoderm development 0.425559947299079 0.107179348286083 0.9146466987245588 1.0 1.0 4 Q12948,Q9HCM4,Q96A65 3 +B cell differentiation 0.3188118811881154 0.1068228860944426 0.914929490882195 1.0 1.0 10 P04637,Q9Y4B6,P05141,P05556,P00813,O15347,Q04721,P43246,P55327 9 +Trophoblast cell migration 0.4907118028515999 0.1067081915393762 0.9150204838074092 1.0 1.0 3 Q07021 1 +Myelin maintenance 0.4240750490324694 0.1040777870256139 0.9171076184961988 1.0 1.0 4 P31751,O15121 2 +Regulation of immune effector process 0.2559205248677096 0.1020370226954591 0.9187272885704748 1.0 1.0 37 P11279,P09601,Q07021,Q08722,P04083,Q9NUQ9 6 +Centromere complex assembly 0.3356093778723867 0.1014088632924303 0.919225900857211 1.0 1.0 7 P50748 1 +Dorsal ventral pattern formation 0.4772876892692584 0.101062755574899 0.9195006433713446 1.0 1.0 2 P35222 1 +Transcription elongation from rna polymerase i promoter 0.4769585253456241 0.1006165473828483 0.9198548604575016 1.0 1.0 2 P18074 1 +Negative regulation of extrinsic apoptotic signaling pathway 0.2768683993964136 0.1002875335515368 0.9201160543793474 1.0 1.0 19 P09601,P61289 2 +Apoptotic cell clearance 0.3350691588313409 0.0995471781567571 0.9207038311416532 1.0 1.0 7 Q8WTV0 1 +Regulation of atp dependent activity 0.2632001651028649 0.0985675662181988 0.921481622987808 1.0 1.0 26 Q15070 1 +Regulation of binding 0.2433337782280501 0.0973915901618743 0.9224154230595816 1.0 1.0 92 Q9BUN8,O75381,P40855,P0DP25,P09601,P16615,Q05655,O75844,P62942,P05067,O75503 11 +Flavin containing compound metabolic process 0.4743252139565524 0.0970994146192132 0.9226474457325252 1.0 1.0 2 Q8NFF5 1 +Regulation of protein localization to chromatin 0.4743252139565525 0.0970994146192132 0.9226474457325252 1.0 1.0 2 Q7Z5K2 1 +Golgi to plasma membrane protein transport 0.2879523277202765 0.0943810101732492 0.9248065001487482 1.0 1.0 14 P98194,Q4J6C6,P61026 3 +Maintenance of lens transparency 0.4716919025674807 0.0936751374972199 0.9253672208165172 1.0 1.0 2 Q12948 1 +Histone arginine methylation 0.4823839315113499 0.0934467140039898 0.9255486804373688 1.0 1.0 3 Q99873,Q86X55 2 +Apoptotic process involved in morphogenesis 0.4820546592031566 0.0929403368363093 0.9259509602518744 1.0 1.0 3 Q12948,P30154 2 +Negative regulation of receptor internalization 0.332518222751998 0.0908404778837168 0.9276193462964336 1.0 1.0 7 O00560 1 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.3253799312086847 0.0904565210194428 0.9279244434553472 1.0 1.0 9 Q14103,Q08211,O60506 3 +Crd mediated mrna stabilization 0.3253799312086847 0.0904565210194428 0.9279244434553472 1.0 1.0 9 Q14103,Q08211,O60506 3 +Alternative mrna splicing via spliceosome 0.2500712957226811 0.0903855630485975 0.9279808287508552 1.0 1.0 44 P23246,Q9UHX1,P09651,P98175,P51114,Q08211,Q9BWF3,Q07666,P62995,Q06787,Q07955,P38159,Q15287,Q96T37,O75525 15 +Regulation of electron transfer activity 0.4800790253539498 0.0899306720352778 0.9283423071385796 1.0 1.0 3 Q99623,O00483 2 +Cellular response to nitrogen starvation 0.468071099407507 0.089116906120196 0.9289890017116008 1.0 1.0 2 O95352 1 +Quinone metabolic process 0.3145572665951948 0.088257511177297 0.9296720082914034 1.0 1.0 10 Q8N0U8 1 +Positive t cell selection 0.4667544437129713 0.0875020936722857 0.9302724213066214 1.0 1.0 2 P42345 1 +Negative regulation of glycolytic process 0.4667544437129712 0.0875020936722857 0.9302724213066214 1.0 1.0 2 Q9NQ88 1 +T helper cell lineage commitment 0.4667544437129713 0.0875020936722857 0.9302724213066214 1.0 1.0 2 P42345 1 +Interleukin 6 mediated signaling pathway 0.4667544437129712 0.0875020936722857 0.9302724213066214 1.0 1.0 2 Q6PD62 1 +Cd4 positive or cd8 positive alpha beta t cell lineage commitment 0.4667544437129713 0.0875020936722857 0.9302724213066214 1.0 1.0 2 P42345 1 +T helper 17 type immune response 0.4667544437129711 0.0875020936722854 0.9302724213066216 1.0 1.0 2 P35232 1 +Receptor metabolic process 0.2570822644352992 0.0843696048963646 0.9327625728790888 1.0 1.0 34 Q15907,Q9UHD9,P02786,O75955,Q99538,P42892,P18031,Q9Y371,Q06787,Q8NBU5,O00560,Q96J02 12 +Organism emergence from protective structure 0.4634628044766316 0.0835637420999945 0.9334032956825846 1.0 1.0 2 Q6PD62 1 +Cobalamin metabolic process 0.4628044766293636 0.0827928721666974 0.9340162368570644 1.0 1.0 2 Q99707 1 +Stress granule disassembly 0.4744813961145745 0.0816686569937023 0.9349102031697556 1.0 1.0 3 P33176,Q07866 2 +Negative regulation of smoothened signaling pathway 0.4744813961145704 0.0816686569936965 0.9349102031697604 1.0 1.0 3 P63244,Q6PHR2 2 +Membrane repolarization 0.3319246791046484 0.0816468492799848 0.9349275452928064 1.0 1.0 8 P05023,O75844,Q96PU5 3 +Pigment granule organization 0.3426688632619497 0.080755717476577 0.9356362253279418 1.0 1.0 5 Q9BXS5,O14617,O00203,O95295 4 +Negative regulation of nervous system development 0.2776356585462667 0.0798508481497026 0.9363558824274794 1.0 1.0 17 Q9NQC3 1 +Plasma membrane organization 0.2603054049728879 0.0791687409714052 0.9368984076203464 1.0 1.0 27 P16615,Q96CP7,Q05655,Q96GC9 4 +Mesenchymal stem cell differentiation 0.4591836734693901 0.0786521554791105 0.9373093019204676 1.0 1.0 2 P35222 1 +Dopaminergic neuron differentiation 0.4591836734693901 0.0786521554791105 0.9373093019204676 1.0 1.0 2 P35222 1 +Canonical wnt signaling pathway involved in osteoblast differentiation 0.4591836734693901 0.0786521554791105 0.9373093019204676 1.0 1.0 2 P35222 1 +Regulation of skeletal muscle tissue development 0.4110671936758934 0.0783332128985155 0.9375629985498954 1.0 1.0 4 O75955,P35222,P41440 3 +Rig i signaling pathway 0.3121723834231754 0.078046528944511 0.9377910410964914 1.0 1.0 10 Q9NUD5,Q99623,Q07021 3 +Entry of bacterium into host cell 0.471331962515648 0.0771917060813548 0.9384710395495596 1.0 1.0 3 Q9BTY2 1 +Regulation of entry of bacterium into host cell 0.471331962515648 0.0771917060813548 0.9384710395495596 1.0 1.0 3 Q9BTY2 1 +Anoikis 0.3303777812299588 0.0762339962453419 0.9392329362825738 1.0 1.0 6 Q07820,P42345 2 +Cellular senescence 0.2727945604086266 0.0760131912457149 0.9394086034660674 1.0 1.0 19 O60313,P67809,O75844,Q05655 4 +Regulation of mononuclear cell migration 0.2764625795069417 0.0733067632370036 0.9415620098979698 1.0 1.0 17 Q99538,Q07021,Q08722,Q5JRA6,P05067 5 +Pteridine containing compound metabolic process 0.2733525923257404 0.0728589443696142 0.9419183647194648 1.0 1.0 18 P00374,Q9H2D1 2 +Keratinization 0.4502962475312729 0.0691855798510639 0.9448419012140664 1.0 1.0 2 Q8NEY8 1 +Protein containing complex localization 0.2478038640234257 0.0671875018074832 0.9464324347544304 1.0 1.0 40 P23246,O43805,Q9BTX1,Q15154,Q14168,Q13277,Q96D46,Q9Y639,P57105,O14617,Q86U38,O15400 12 +Positive regulation of execution phase of apoptosis 0.4632709458216604 0.0662901130438091 0.9471468545597768 1.0 1.0 3 Q8IXJ6 1 +Bile acid biosynthetic process 0.3249426716805352 0.0658203872175587 0.9475208247789084 1.0 1.0 7 Q96SU4,O14734 2 +Embryonic heart tube development 0.3273413100474154 0.0655475104349484 0.9477380797837764 1.0 1.0 8 P42892 1 +Coenzyme a metabolic process 0.3272030082652221 0.0650689328231033 0.9481191160097492 1.0 1.0 8 P35610,Q8WVC6 2 +Astrocyte differentiation 0.2927832668013911 0.064028240960101 0.9489477399040824 1.0 1.0 12 P05067 1 +Tangential migration from the subventricular zone to the olfactory bulb 0.4443712969058612 0.0634084689902268 0.9494412435451504 1.0 1.0 2 O94813 1 +Olfactory lobe development 0.4443712969058612 0.0634084689902268 0.9494412435451504 1.0 1.0 2 O94813 1 +Cellular response to inorganic substance 0.252419836205088 0.0626442133131293 0.95004982140157 1.0 1.0 36 Q14103,Q9NQ88,P09601,Q99538,Q6NUK1,Q06787,O95831,P05067,Q92542,P55011,Q14168 11 +Cellular response to fatty acid 0.3348444833447896 0.0623094307303782 0.9503164184350564 1.0 1.0 5 Q15120,P50416 2 +Positive regulation of establishment of protein localization 0.2351125667236477 0.0622636907826838 0.9503528429080784 1.0 1.0 84 O43464,P98194,P49755,Q9Y6B6,Q99832,Q9C0E2,P50402,Q9NR31,Q9GZY8,Q9Y282,P51572,O14737,P27105,Q5T9L3,Q9Y5U9,O00429,Q9H4A6,Q05655,Q9Y371,P55786 20 +Negative regulation of calcium mediated signaling 0.4593348699374399 0.0612550468839966 0.9511560909243622 1.0 1.0 3 P42345,Q9UHD1 2 +Negative regulation of calcineurin mediated signaling 0.4593348699374399 0.0612550468839966 0.9511560909243622 1.0 1.0 3 P42345,Q9UHD1 2 +Regulation of protein localization to centrosome 0.459334869937428 0.0612550468839818 0.951156090924374 1.0 1.0 3 Q9UNZ2,P37198 2 +Regulation of t cell differentiation 0.3002734001518003 0.0603901634726556 0.9518448927715952 1.0 1.0 11 O96005,Q9BXW9,P04083 3 +Spermatid differentiation 0.2764550264550271 0.0585807040581769 0.9532860802155448 1.0 1.0 16 P62826,Q96PU8,Q8TDI0,Q9GZT3,P43034,Q9Y2H6,Q08J23,P09622,P26583,Q96KQ7,Q9H6S0,Q15645,Q96SB4,Q96SI9,A0AVF1 15 +Ventral spinal cord development 0.4387755102040839 0.0583302141896601 0.9534856010369964 1.0 1.0 2 Q6Y7W6 1 +Cerebral cortex neuron differentiation 0.3327841845140074 0.0576529290563282 0.9540250884605874 1.0 1.0 5 P43034,Q96ST3,Q8TDI0,P50542 4 +Positive regulation of glucose metabolic process 0.3992094861660132 0.0571038720545017 0.9544624520051452 1.0 1.0 4 O75746,P31751,Q16531 3 +Positive regulation of cellular carbohydrate metabolic process 0.3992094861660132 0.0571038720545017 0.9544624520051452 1.0 1.0 4 O75746,P31751,Q16531 3 +Activation of cysteine type endopeptidase activity 0.4553836022390448 0.0563881065734473 0.9550326314605412 1.0 1.0 3 Q99538,Q12797 2 +Response to camp 0.3069296091744168 0.0561103574644816 0.9552538928757164 1.0 1.0 10 P05067 1 +Regulation of peptidyl tyrosine phosphorylation 0.2564076844784186 0.0530526370618452 0.9576899684198246 1.0 1.0 28 O95684,P61225,Q9H2J4,P18031,Q05655,P05067,O00165 7 +Regulation of lipophagy 0.4520550499759597 0.0524324564949767 0.9581841131329192 1.0 1.0 3 O15269 1 +Protein refolding 0.2983516521441807 0.0520649068792111 0.9584769752762732 1.0 1.0 11 P62942 1 +Mitochondrial fragmentation involved in apoptotic process 0.3957643615169569 0.051335798622444 0.9590579425242076 1.0 1.0 4 Q9GZY8 1 +Post embryonic development 0.2812063486280884 0.051124111481854 0.9592266229282322 1.0 1.0 13 Q96A33 1 +Female meiosis chromosome segregation 0.4298880842659667 0.0509884644964984 0.9593347125905654 1.0 1.0 2 P53350 1 +Response to monosaccharide 0.2557889677503409 0.050659356498304 0.9595969638544892 1.0 1.0 29 Q15907,P49770,Q8N5M9,Q9NR50,Q99808 5 +Neuron cellular homeostasis 0.3952262080181519 0.050450980590907 0.9597630114436086 1.0 1.0 4 P20020 1 +Embryonic heart tube morphogenesis 0.4497859729996526 0.0498107532008795 0.9602731975066006 1.0 1.0 3 Q04721,Q15363 2 +Rna import into mitochondrion 0.4256089532587254 0.0477572521965477 0.9619097054618906 1.0 1.0 2 Q15388 1 +Glutamate biosynthetic process 0.4478103391504821 0.0475771063424586 0.9620532778549562 1.0 1.0 3 P00367,O94925 2 +Glycolytic fermentation 0.4478103391504695 0.0475771063424447 0.9620532778549672 1.0 1.0 3 P04637,Q9NQ88 2 +Fermentation 0.4478103391504695 0.0475771063424447 0.9620532778549672 1.0 1.0 3 P04637,Q9NQ88 2 +Negative regulation of circadian rhythm 0.4249506254114575 0.0472770885630858 0.9622923883377696 1.0 1.0 2 P23246 1 +Regulation of anion channel activity 0.4229756418696535 0.0458632394903598 0.9634192539657483 1.0 1.0 2 P08183 1 +Regulation of cardiac conduction 0.4452217593993272 0.044718954476207 0.9643313253236548 1.0 1.0 3 P16615 1 +Positive regulation of peptidyl lysine acetylation 0.3178371249587841 0.0435241492536572 0.9652837144426476 1.0 1.0 7 Q969T9,Q49A26,O95251,Q9Y230,P54646,Q9NWS0 6 +Regulation of transcription from rna polymerase ii promoter in response to hypoxia 0.443255626945331 0.0425995615630977 0.9660207449964432 1.0 1.0 3 Q8IXJ6 1 +Regulation of reactive oxygen species metabolic process 0.2549774861118501 0.041907420065155 0.9665725012395634 1.0 1.0 27 Q9BSK2,Q8IXJ6,P52789,Q05655,P00374 5 +Response to antibiotic 0.3202506596306097 0.0415682965046286 0.966842847110982 1.0 1.0 8 P50416,P04637,O60341,O95251,P62829,P07900,P61160 7 +Positive regulation of vesicle fusion 0.4422049581624131 0.0414850853563568 0.9669091827799852 1.0 1.0 3 P04083 1 +Positive regulation of histone acetylation 0.3177323665128573 0.040617825271127 0.9676005733717188 1.0 1.0 6 Q969T9,Q49A26,O95251,Q9Y230,Q9NWS0 5 +Cellular response to mechanical stimulus 0.3114483668756299 0.0376878423723884 0.969936569492662 1.0 1.0 9 Q15149,Q99439,Q9Y624,O14757,P49327,P58546,P11166,P27361 8 +Hyperosmotic response 0.3153940148454592 0.0361269852918789 0.97118110521721 1.0 1.0 7 Q9BPX6,O95202,P55011 3 +Trna methylation 0.3018839164445124 0.0356847600622905 0.9715337225214452 1.0 1.0 10 Q9UBP6 1 +Ensheathment of neurons 0.2562751306412532 0.0354071573161662 0.9717550775789838 1.0 1.0 25 Q96PU8,Q8IXJ6,P49770,P31751,O15121,Q9Y2J2,P42345,P53634,Q92542 9 +Membrane fission 0.3848262279842512 0.0342058229278813 0.9727130232347724 1.0 1.0 4 O00429 1 +Positive regulation of protein acetylation 0.3179419525066055 0.0340101197953024 0.9728690809409472 1.0 1.0 8 O00571,Q969T9,Q49A26,O95251,Q9Y230,P54646,Q9NWS0 7 +Histone h3 k14 acetylation 0.3151116992496792 0.033681867085635 0.9731308387374238 1.0 1.0 6 Q03164,P55201 2 +Positive regulation of interleukin 6 production 0.3178280413010198 0.0336404249482269 0.9731638860512162 1.0 1.0 8 P05067 1 +Meiotic spindle assembly 0.3843873517786614 0.0335557832024307 0.973231382286638 1.0 1.0 4 O14777,Q08379,O14965 3 +Positive regulation of membrane potential 0.3212623998686306 0.0331661981635143 0.9735420532427286 1.0 1.0 5 Q9UJZ1,Q8IWA4 2 +Intestinal epithelial cell development 0.3996050032916416 0.0319580171223521 0.974505531264672 1.0 1.0 2 Q9NQ88 1 +Columnar cuboidal epithelial cell maturation 0.3996050032916416 0.0319580171223521 0.974505531264672 1.0 1.0 2 Q86UL3 1 +Intestinal epithelial cell differentiation 0.3996050032916416 0.0319580171223521 0.974505531264672 1.0 1.0 2 Q9NQ88 1 +Negative regulation of autophagosome assembly 0.3832958267265374 0.0319514478661036 0.9745107700974268 1.0 1.0 4 O75396 1 +Regulation of synaptic transmission glutamatergic 0.3831831302665503 0.0317868093567118 0.9746420659303644 1.0 1.0 4 Q8NBU5,Q15042 2 +Response to l glutamate 0.382702952027885 0.0310874193096231 0.9751998227580964 1.0 1.0 4 O95831,O94874 2 +Negative regulation of leukocyte proliferation 0.3141067897165527 0.031063381413424 0.9752189929659644 1.0 1.0 6 Q14160,Q92990,Q9Y6D9,P10644,Q96J02 5 +Negative regulation of t cell proliferation 0.3141067897165527 0.031063381413424 0.9752189929659644 1.0 1.0 6 Q14160,Q92990,Q9Y6D9,P10644,Q96J02 5 +Cellular response to reactive oxygen species 0.2533818365816387 0.031008097761366 0.9752630816997748 1.0 1.0 27 Q99720,Q96P47,Q05655,P00374 4 +Regulation of brown fat cell differentiation 0.3946675444371322 0.0296281618499093 0.9763636052603246 1.0 1.0 2 Q9C0B1 1 +Positive regulation of protein k63 linked ubiquitination 0.3940092165898641 0.029332033160117 0.976599779120223 1.0 1.0 2 O00571 1 +Sperm dna condensation 0.3913759052007924 0.0281806716193448 0.9775180529152404 1.0 1.0 2 Q8TDI0 1 +Regulation of translation in response to stress 0.2847586229652297 0.0279425616246212 0.9777079624161038 1.0 1.0 12 Q13217,P51812,Q15418,Q15363 4 +Regulation of response to wounding 0.2723716010869588 0.0261092745844529 0.9791701795368856 1.0 1.0 15 O75122,Q96G23,Q05655,P42345,P04083,P55011 6 +Centriole elongation 0.3851217906517469 0.0256513058589491 0.9795354633569988 1.0 1.0 2 O43633 1 +Negative regulation of stem cell differentiation 0.311867286404066 0.0253103317677472 0.979807433013194 1.0 1.0 6 Q8WX92 1 +Positive regulation of wound healing 0.3165225849039373 0.0238596500636793 0.980964559696945 1.0 1.0 5 P04083 1 +Fibroblast proliferation 0.2718550930618683 0.0235806432359396 0.9811871123185284 1.0 1.0 15 O75844,Q08211 2 +Protein kinase b signaling 0.2582060432957326 0.0234337922710281 0.981304250067061 1.0 1.0 23 Q9NQC3,Q8IXJ6,Q86UE4,Q07021,O95429,O00165 6 +Memory 0.3074499037936458 0.0234271465083231 0.9813095511632022 1.0 1.0 9 Q9BPZ3,O00264 2 +Peripheral nervous system myelin maintenance 0.3765635286372639 0.0226269514174123 0.9819478452063032 1.0 1.0 2 P31751 1 +Presynaptic modulation of chemical synaptic transmission 0.3716260697827541 0.0210936229561604 0.9831709719083696 1.0 1.0 2 P35268 1 +Regulation of hematopoietic stem cell proliferation 0.3693219223173166 0.0204274581628296 0.9837023799713052 1.0 1.0 2 O95251 1 +Positive regulation of peptidyl serine phosphorylation 0.271165018796059 0.0202177479230035 0.983869669983958 1.0 1.0 15 P05067 1 +Positive regulation of dna demethylation 0.3627386438446373 0.0186866159165789 0.9850911053434206 1.0 1.0 2 Q93009 1 +Trna wobble uridine modification 0.3614219881501012 0.0183659572481832 0.985346910040293 1.0 1.0 2 O75648 1 +Trna wobble base modification 0.3614219881501012 0.0183659572481832 0.985346910040293 1.0 1.0 2 O75648 1 +Androgen metabolic process 0.3131397770437038 0.0174903892399133 0.9860453999505934 1.0 1.0 5 O95470 1 +Embryonic body morphogenesis 0.4145538360223857 0.0164793286384929 0.9868519932065584 1.0 1.0 3 O75122,Q7Z460 2 +Regulation of intestinal absorption 0.35220539828835 0.0163571592144755 0.9869494571667072 1.0 1.0 2 Q6P1A2 1 +T cell tolerance induction 0.3508887425938142 0.01610186601297 0.9871531248456112 1.0 1.0 2 Q96J02 1 +Lymphocyte anergy 0.3508887425938142 0.01610186601297 0.9871531248456112 1.0 1.0 2 Q96J02 1 +Response to calcium ion 0.2569697772939218 0.0159215673941662 0.9872969638901394 1.0 1.0 23 Q14103,P0DP25,Q99538,Q6NUK1,Q92542 5 +Central nervous system projection neuron axonogenesis 0.3485845951283766 0.015672882840764 0.9874953606985616 1.0 1.0 2 O94813 1 +Histone h4 k20 methylation 0.3475971033574745 0.0154957864023756 0.9876366460542064 1.0 1.0 2 O96028 1 +Copii coated vesicle budding 0.2619538792214854 0.0145510924355943 0.9883903176989116 1.0 1.0 19 P49755,Q15363,Q5JRA6,Q9HCU5,Q9NR31 5 +Positive regulation of lymphocyte mediated immunity 0.2699563452201433 0.0143704877759237 0.9885344043021927 1.0 1.0 15 Q9NUQ9,P11279,O15400 3 +Regulation of jnk cascade 0.2813199022632389 0.0131032634920859 0.9895454075321604 1.0 1.0 12 P05067 1 +Synaptic vesicle budding 0.4086269344748135 0.0121389877754648 0.9903147269330406 1.0 1.0 3 O14617,O00203 2 +Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process 0.4086269344748062 0.0121389877754595 0.9903147269330448 1.0 1.0 3 P49755,O75116 2 +Regulation of aspartic type peptidase activity 0.4086269344748062 0.0121389877754595 0.9903147269330448 1.0 1.0 3 P49755,O75116 2 +Regulation of gtp binding 0.3065421653861767 0.0120899583775289 0.9903538438621606 1.0 1.0 6 O75503 1 +Positive regulation of excitatory postsynaptic potential 0.3186306780776852 0.0118026838414697 0.9905830394230476 1.0 1.0 2 Q9UQB8 1 +B cell lineage commitment 0.3179723502304175 0.0117466039883336 0.9906277815703476 1.0 1.0 2 P04637 1 +Glomerular epithelial cell differentiation 0.3682476943346501 0.0116075012971332 0.9907387618933944 1.0 1.0 4 P80723,Q04721,P11047 3 +Cohesin loading 0.302172481895987 0.0106704012660782 0.991486413128432 1.0 1.0 2 Q7Z5K2 1 +Gamma aminobutyric acid metabolic process 0.2992100065832814 0.0105184221973598 0.9916076680756978 1.0 1.0 2 O43175 1 +Regulation of wound healing spreading of epidermal cells 0.3673455881807551 0.0104912748657792 0.9916293273173308 1.0 1.0 4 O75122 1 +Wound healing spreading of epidermal cells 0.3673455881807551 0.0104912748657792 0.9916293273173308 1.0 1.0 4 O75122 1 +Regulation of apoptotic dna fragmentation 0.2718894009216618 0.0096285959226787 0.9923176106768076 1.0 1.0 2 O95831 1 +Regulation of dna catabolic process 0.2718894009216618 0.0096285959226787 0.9923176106768076 1.0 1.0 2 O95831 1 +Positive regulation of amyloid precursor protein catabolic process 0.3666007905138397 0.0095783410090666 0.992357706447488 1.0 1.0 4 Q96P70,Q13492,O75116 3 +Bone maturation 0.2679394338380542 0.0095561411608053 0.9923754185530358 1.0 1.0 2 Q15125 1 +Jnk cascade 0.2643779492479079 0.008889599960391 0.9929072188578368 1.0 1.0 17 O00560,P05067 2 +Interleukin 2 production 0.3057529911896735 0.0083131221796128 0.993367164557906 1.0 1.0 7 P04083 1 +Progesterone receptor signaling pathway 0.4027000329272303 0.008129806476415 0.99351342438392 1.0 1.0 3 P35232,Q969T9 2 +Regulation of cytoplasmic translational initiation 0.3990993881036093 0.0058499599002132 0.995332433936584 1.0 1.0 3 Q9Y5A9 1 +Cellular defense response 0.3974316759960409 0.0048327701952668 0.9961440222851166 1.0 1.0 3 P05556,Q08380 2 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.2695294765746915 0.0039609661255229 0.9968396145465984 1.0 1.0 14 O76024,O60313,P46379,P18031,O95831,Q96HE7 6 +Microtubule nucleation 0.2694080325105935 0.003404730007237 0.997283423742034 1.0 1.0 14 O75122,Q9BSJ2,Q9HD47 3 +Positive regulation of inclusion body assembly 0.3944682252222597 0.0030845113284199 0.9975389199359715 1.0 1.0 3 P49427,P62195 2 +Cellular oxidant detoxification 0.2588292368540879 0.0029378029179538 0.9976559757808396 1.0 1.0 20 P00374,P78417 2 +Regulation of receptor internalization 0.2707640074897129 0.0029302689894886 0.9976619869601704 1.0 1.0 13 O00560,Q8NBU5,Q06787,Q9UHD9 4 +Spermatid nucleus differentiation 0.3915047744484696 0.0014105014324028 0.9988745830572676 1.0 1.0 3 P26583,Q8TDI0 2 +3 utr mediated mrna stabilization 0.3030003297065545 0.0007814710520166 0.9993764763763456 1.0 1.0 7 Q13151,P98175,Q92615,P07910,Q15717,Q13148 6 +Positive regulation of potassium ion transmembrane transporter activity 0.3891998682910771 0.0001586412639733 0.9998734225853004 1.0 1.0 3 P54709,P50570 2 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..987eff569cbdc3e28d8ca90921cb94a83f994fa3 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Acrosome reaction", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activation of store operated calcium channel activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Acylglycerol transport", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular node development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "Bundle of his cell to purkinje myocyte signaling", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Common bile duct development", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Convergent extension involved in gastrulation", "Convergent extension involved in organogenesis", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Copulation", "Coronary vasculature development", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Craniofacial suture morphogenesis", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Dipeptide transmembrane transport", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Endocannabinoid signaling pathway", "Endocardium development", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glomerulus morphogenesis", "Glomerulus vasculature morphogenesis", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "Hexose phosphate transport", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lacrimal gland development", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene d4 metabolic process", "Leukotriene metabolic process", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteolysis", "Lymph vessel development", "Lymph vessel morphogenesis", "Lymphangiogenesis", "Lymphatic endothelial cell differentiation", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage differentiation", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Marginal zone b cell differentiation", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic process involved in development", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of g0 to g1 transition", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hexokinase activity", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of ribosome biogenesis", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna polymerase ii regulatory region sequence specific dna binding", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 1 signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide import across plasma membrane", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation cycle", "Ovulation cycle process", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine acyl chain remodeling", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of digestive system process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial cell proliferation involved in wound healing", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix constituent secretion", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of granulocyte differentiation", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoclast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of peroxisome proliferator activated receptor signaling pathway", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of store operated calcium channel activity", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic development", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c activating g protein coupled receptor signaling pathway", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of acrosome reaction", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen processing and presentation", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endosome to plasma membrane protein transport", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix constituent secretion", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intestinal lipid absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphangiogenesis", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic nuclear division", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast development", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of cardiac muscle", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sensory perception", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lithium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal complex assembly", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Store operated calcium entry", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urea cycle", "Urea metabolic process", "Ureter development", "Urogenital system development", "Uronic acid metabolic process", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG8", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANKFY1", "ANKHD1", "ANKLE2", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATG13", "ATG16L1", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BDH2", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRIX1", "BRPF1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf76", "C12orf43", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C20orf24", "C2orf49", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2D", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCDC88A", "CCDC93", "CCDC94", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPK", "CENPU", "CENPV", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COG4", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPE", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP2", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP2", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERCC2", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM162A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FOXRED2", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD2A", "HIKESHI", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK3", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISCU", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1211", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFAP3", "KIFBP", "KIFC1", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "M6PR", "MACF1", "MAD1L1", "MAGED2", "MAGT1", "MAK16", "MAN1A2", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAPK1", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCH5", "MARCKS", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBIP", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED24", "MED25", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL14", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MIB1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL20", "MRPL22", "MRPL23", "MRPL24", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL47", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS14", "MRPS15", "MRPS16", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NACC1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFKBIE", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F2", "NRBP1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NUB1", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OSTM1", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDS5A", "PDS5B", "PDSS1", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11A", "PEX14", "PEX16", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PWP2", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC15A4", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D10A", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TES", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLCD1", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM33", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMLHE", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN6", "TSR1", "TSR2", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3C", "UBE4A", "UBE4B", "UBLCP1", "UBQLN2", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WASHC3", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WLS", "WNK1", "WRAP53", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZMPSTE24", "ZMYM4", "ZNF207", "ZNF24", "ZNF281", "ZNF326", "ZNF593", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAAS", "AASDHPPT", "ABCB1", "ABCB7", "ABCD3", "ABHD10", "ACAT2", "ACOT8", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL6", "ACTN4", "ACTR2", "ADA", "ADPGK", "AGAP3", "AGK", "AGPAT1", "AGPAT5", "AGPS", "AIFM1", "AK3", "AKT2", "ALDH3A2", "ALDH6A1", "ALG1", "ALG12", "ANAPC7", "ANKLE2", "ANXA1", "AP1M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APOL2", "APOO", "APP", "ARL1", "ARL6IP1", "ARL6IP5", "ARMC1", "ARMCX3", "ARV1", "ASAH1", "ASNA1", "ASPH", "ATAD1", "ATAD3A", "ATAD3B", "ATG13", "ATG16L1", "ATG7", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1E1", "ATPIF1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BAG4", "BAG6", "BAIAP2", "BASP1", "BCAP31", "BCL2L13", "BET1", "BNIP1", "BRPF1", "BSG", "BUB1B", "C10orf76", "C12orf73", "C19orf70", "C1QBP", "CALM3", "CANX", "CARM1", "CASK", "CCDC47", "CCT7", "CD47", "CDC23", "CDC34", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDS2", "CEP44", "CERS1", "CERS2", "CETN2", "CHCHD3", "CHD5", "CHEK1", "CHMP1A", "CHMP2A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST12", "CHST14", "CIRBP", "CISD1", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLN5", "CLNS1A", "CLPP", "CLPTM1", "CLUH", "CNN2", "CNNM3", "CNOT1", "CNOT9", "COA3", "COG4", "COLEC12", "COMT", "COPE", "COPS3", "COPS4", "COPS5", "COPS7A", "COPS8", "COX11", "COX14", "COX15", "COX18", "COX4I1", "COX5A", "COX7A2", "COX7A2L", "CPE", "CPT1A", "CPT2", "CRTAP", "CSE1L", "CSNK1A1", "CSTB", "CTNNB1", "CTR9", "CTSA", "CTSC", "CYB5B", "CYB5R3", "CYP51A1", "DAGLB", "DAZAP1", "DCAF1", "DCAKD", "DCTN2", "DCTPP1", "DDB1", "DDRGK1", "DDX28", "DDX3X", "DDX5", "DEGS1", "DERL1", "DHCR24", "DHDDS", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX8", "DHX9", "DIABLO", "DLD", "DNA2", "DNAJC1", "DNAJC3", "DNM1L", "DNM2", "DOHH", "DOLPP1", "DPM1", "DSG2", "DYNC1I2", "EBP", "ECE1", "EHMT2", "EIF2B2", "EIF2B3", "EIF3E", "ELAVL1", "ELMOD2", "EMC2", "EMC4", "EMC7", "EMD", "EPB41L3", "EPB41L5", "EPHX1", "ERAP1", "ERCC2", "ERGIC2", "ERGIC3", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ETFDH", "ETNK1", "EXOC4", "EXTL3", "F11R", "FADS2", "FAF2", "FAH", "FAM162A", "FAM208A", "FAM49B", "FAM8A1", "FANCD2", "FASN", "FDFT1", "FDPS", "FGFR1OP", "FKBP10", "FKBP14", "FKBP1A", "FKBP7", "FKBP9", "FLAD1", "FLOT1", "FMR1", "FN3KRP", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FTO", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "G6PD", "GAA", "GALNT1", "GALNT2", "GBA", "GBF1", "GDAP1", "GGCX", "GGH", "GGT7", "GHITM", "GIGYF2", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLS", "GLUD1", "GLYR1", "GM2A", "GNAI2", "GNS", "GOLGA2", "GOLGA5", "GOLPH3", "GORASP2", "GOSR1", "GOSR2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPR108", "GPX8", "GRPEL1", "GSTO1", "GSTZ1", "GUSB", "HACD3", "HADH", "HADHA", "HAX1", "HEATR3", "HEXA", "HGS", "HIGD2A", "HIKESHI", "HK2", "HLA-A", "HLA-C", "HM13", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HS2ST1", "HSD17B11", "HSD17B12", "HSP90AA1", "HSPA13", "HTRA2", "ICMT", "IER3IP1", "IGF2R", "ILVBL", "IMMT", "IMPAD1", "INA", "INPP4A", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IST1", "ITCH", "ITGB1", "IWS1", "JAGN1", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIAA1211", "KIF3A", "KIF5B", "KIFAP3", "KLC1", "KMT2A", "KNTC1", "KPNA2", "LAMC1", "LAMP1", "LAMTOR2", "LARP4B", "LARS", "LBR", "LDAH", "LETM1", "LGALS3BP", "LGMN", "LMAN2", "LMF2", "LNPEP", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRRC59", "LRRC8C", "LTA4H", "LYPLA1", "LYSMD3", "MAD1L1", "MAGT1", "MAN1A2", "MAN2B1", "MANBA", "MAPK3", "MAPRE2", "MARCH5", "MAVS", "MBOAT7", "MCAT", "MCL1", "MCU", "METTL1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGST2", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MIPEP", "MMGT1", "MOSPD2", "MOV10", "MPC2", "MPP2", "MPV17L2", "MRPS14", "MSH2", "MSMO1", "MTAP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTOR", "MTPN", "MTR", "MTX1", "MTX2", "NAGLU", "NAMPT", "NAP1L1", "NASP", "NCKAP1", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFAF2", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFS2", "NEDD4L", "NELFB", "NLN", "NMD3", "NNT", "NOP9", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPTN", "NR2F2", "NSD2", "NSFL1C", "NSUN2", "NT5C3B", "NTMT1", "NUB1", "NUCB1", "NUCB2", "NUDT12", "NUP107", "NUP160", "NUP35", 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6.845681299139724e-08 3.992038757121455e-14 +Mitochondrion 162 596 4.049196194288579 5.139384701657868e-05 150.5606796116505 610.75 0.3893280889581553 0.5444893646695418 55.48150839960472 53.47985851692477 2.1394883185001157 0.4272675793576402 1.0407773058378872e-17 1.8442712687965376e-10 2.59163146623465e-13 5.25437019227708e-15 1.5349251730146485e-21 +Intrinsic component of mitochondrial inner membrane 21 34 4.011012488074693 6.045891191508446e-05 13.946601941747574 31.446601941747577 1.7062420859184484 0.2149692261988765 6.992163651608136 3.3601842163433866 1.8185871159494191 0.3070405082296492 2.6600726898761803e-09 9.216009865795702e-05 2.100416788694277e-08 1.68000802763977e-09 4.573353564783897e-14 +Endoplasmic reticulum golgi intermediate compartment membrane 23 29 3.9068575535876833 9.350423896803406e-05 10.49271844660194 25.839805825242717 1.5441023898993702 0.2324243418613106 5.505729177420246 3.7718384126099376 1.49831312620529 0.2965572765953523 3.426037665715069e-05 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0.0009220295430605 6.817961165048544 16.400485436893202 0.815819301321945 0.3904411977369264 3.451940177462974 2.047328298639296 1.2919706717077657 0.3464717655445403 0.0096467194572669 0.1553991536419083 0.0443091130960601 0.0097601039903573 3.22142282967417e-05 +Transport vesicle 40 98 3.2840188057049056 0.0010233809336663 26.046116504854368 92.34708737864078 0.9512017428916244 0.4458616213657612 9.46815354334768 9.09007867686459 1.424803887648301 0.3967491654773343 0.0003694194213798 0.3582794844835456 0.2423406323390604 0.0527943865241834 9.882403541961384e-06 +Copii coated er to golgi transport vesicle 19 34 3.275772792210537 0.0010537329580444 10.810679611650484 32.4247572815534 0.9209697551014924 0.3949407296339237 5.01338814607213 3.9617918728777735 1.2509556054930144 0.3456813773327062 0.0130235685295286 0.2766173679843171 0.4775398588675821 0.2210522410556178 0.0013809720441502 +Intrinsic component of golgi membrane 11 12 3.0923910558554795 0.0019855109840893 4.655339805825243 10.08495145631068 1.3178763872097854 0.2129685736028588 2.6046347098798024 1.9780511021437377 1.2704958978874823 0.2699640456705705 0.0001494809334509 0.1835089509173778 0.3339976348230559 0.2707185745648809 0.0001500964424578 +Vacuolar membrane 41 127 3.090488831808348 0.0019982731946717 31.91504854368932 121.20631067961163 0.8693310080509177 0.3422944242486927 10.598363436017626 13.850227259030053 1.9844114292962869 0.3837860427998523 5.07580798503278e-08 0.4851629446799355 0.0156550103902373 2.105890306869479e-06 5.115412256887092e-09 +Azurophil granule 37 73 3.0769706276707094 0.0020911590545384 20.46359223300971 67.00485436893204 0.4795255752980384 0.3097891700346699 6.177875864944045 5.290582926033595 2.1760997104513735 0.3628132485163926 2.80681042056749e-07 1.0 0.6727295364723632 0.0004653137266356 1.752932665118538e-10 +Golgi cisterna membrane 14 19 3.056598989961432 0.0022386354825447 6.233009708737864 17.101941747572816 0.7930989258143627 0.3092897028410761 3.2184356191878685 3.952300069740005 1.3504727992091758 0.2953094162507478 0.1331835459157892 1.0 0.3955810682553247 0.1312000588255236 0.1072426750643267 +Snare complex 13 21 3.030784966016389 0.002439188941667 6.20873786407767 15.79368932038835 0.8138466711937282 0.3737991711938105 3.1112263618988054 3.010283181947674 1.1802712183474584 0.3261149602927671 0.0010460803433829 0.187449079081247 0.3404254693467198 0.0854582473740603 4.502168619247678e-06 +Transport vesicle membrane 20 46 2.981659796328795 0.0028669038619217 12.62135922330097 42.37378640776699 0.5402420874587609 0.5343084089707166 5.404271063272784 4.511161156897919 1.052801184280702 0.3556606283757049 0.1160620057331639 1.0 0.3526837640973719 0.3812374129900513 0.0230489533257871 +Cytochrome complex 4 15 2.914411221216296 0.0035636015076263 6.021844660194175 16.08495145631068 1.0267019648816196 0.2321293206617183 2.9315837025395948 1.6175814223208935 1.624269406530766 0.2919563386676546 0.0042469242101728 0.000349084453734 0.0026246094830452 0.0049571663496986 0.012033886898071 +Endoplasmic reticulum tubular network 8 13 2.905105493508678 0.003671293379508 4.456310679611651 11.402912621359222 0.7597390036291544 0.4204688348420043 2.5600618129260964 1.9933849978482647 1.110800197793671 0.3406591463359876 0.000126118181071 1.0 0.191600110602388 0.0017432511761074 5.564378317152988e-05 +Microbody membrane 15 25 2.902518823183546 0.0037017491332305 9.83980582524272 26.8373786407767 1.0322166739723002 0.3740701224912098 5.101262737371427 4.075770333088885 1.3138416014090577 0.3534887732287703 0.0201979736142584 1.0 0.4242240140575919 0.1596086760652474 0.0059899182032361 +Membrane protein complex 120 283 2.8964461233174355 0.0037741544183769 80.6747572815534 286.40291262135923 0.8072324880333213 0.5482017098759524 27.14508025817277 25.65052264389531 1.8803092756171496 0.4277745875695662 2.8462911414210615e-14 1.880357463702886e-06 1.2130729891092608e-08 5.8499197177292295e-12 6.777797039495626e-17 +Outer mitochondrial membrane protein complex 12 16 2.8927889450293227 0.0038183778419778 7.157766990291262 15.730582524271844 1.3245491566248977 0.2112996285983387 3.5767402396348245 0.8689557679680192 1.477430451036954 0.2853006280851536 6.987158571917604e-05 0.0040679264544396 3.4550328168080166e-05 9.22092773458021e-05 2.2237850571674797e-06 +Nuclear inner membrane 8 21 2.870747242843826 0.0040950281618654 7.347087378640777 20.57281553398058 1.3204335588742686 0.2519451141048848 3.6006224195129035 1.9968516080603145 1.2188770932171689 0.2896682474252494 0.0046822428593577 0.1835089509173778 0.0614247268920475 0.0032788281256578 0.0037872519575486 +Mitochondrial protein containing complex 47 154 2.810181711805588 0.0049513536187733 45.62621359223301 153.59708737864077 0.8032126729603613 0.4024101172023991 21.080430630469312 12.423857071229754 2.191669513941161 0.4117346592056412 1.0376354965191527e-14 1.877004006009265e-09 2.617247672267695e-13 2.954174168702711e-12 5.464840725273685e-15 +Azurophil granule membrane 14 24 2.747174571340241 0.0060111129780455 7.856796116504855 21.259708737864077 1.0757479237162697 0.2373572682944545 3.393508570011604 2.63895903142419 1.639408148995933 0.2881313440808664 0.0015763626964056 1.0 1.0 0.0998367022916053 9.144325926849002e-06 +Endoplasmic reticulum protein containing complex 28 60 2.699407203880937 0.0069463124774422 20.067961165048544 61.213592233009706 0.544324442160867 0.4875881372361492 7.672624563199495 5.300944201362535 1.5348103009085623 0.3893079894443684 0.0002111903756084 1.0 1.0 0.0158134072973611 4.048942520430883e-06 +Ion channel complex 6 17 2.6829203273537554 0.0072982374896015 3.9563106796116503 17.199029126213592 -0.8839101600334985 0.3158173185808598 2.545323902287457 3.2071217821226017 1.185146807986282 0.2839072328217335 0.0094178301707895 0.0366902203239334 0.0030981129560367 0.0180040169030602 0.0325410063420203 +Tim23 mitochondrial import inner membrane translocase complex 4 7 2.6630027763165174 0.0077446775139933 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 2.8990981730909747e-05 1.6752670706047648e-05 2.515038607063009e-06 3.2862197875785204e-06 9.662113775844424e-05 +Respiratory chain complex iii 1 7 2.662072318314616 0.0077661191086624 2.5145631067961167 7.186893203883495 0.8648567981956616 0.2640480169416735 1.5224155414895728 0.9433070612984726 1.3007640218760226 0.2795290338624424 0.084681911188206 0.0017062060788896 0.0066572828402184 0.0382400085743442 0.129364196063302 +Intrinsic component of mitochondrial outer membrane 9 13 2.6611189840287706 0.0077881430209856 5.004854368932039 12.186893203883496 0.537559322132711 0.4142348023165385 2.5976045215999015 2.144426747635188 1.2224430201503769 0.3320793466689031 0.2157874462253757 0.1049896535105009 0.1993869387044997 0.1060727287920157 0.0043329575683166 +Synaptic vesicle membrane 7 17 2.631869904243404 0.0084916372097461 5.099514563106796 14.07766990291262 0.7734258277348643 0.4227625879426745 2.579286376297321 2.2325453295101236 1.0485572818049853 0.3297289695807819 0.027277006892699 1.0 0.1163398228410075 0.0600215848699845 0.0278547210480151 +Specific granule membrane 6 18 2.6251954598661427 0.0086599238682447 4.703883495145631 15.434466019417476 0.8701513897757543 0.3699585460258285 2.477017558764293 2.6655071934549124 0.9998631482292508 0.308737972868479 0.0022955856204248 0.2107016729382093 0.3777229935777695 0.006410021202963 0.0090060858517451 +Golgi stack 20 35 2.553035940983861 0.0106788476128691 9.67233009708738 31.25242718446602 0.7055900861920908 0.4265468940333196 4.557817503574521 5.847941213698429 1.2226912303929196 0.3463938041520717 0.0320553924065836 1.0 0.6136637824136402 0.4251492251315837 0.0486153614380544 +Proton transporting two sector atpase complex proton transporting domain 5 10 2.5027630541794803 0.0123228012654461 4.053398058252427 10.283980582524272 1.020958321179617 0.2307004649223604 1.8491832641634656 1.1862626633334956 1.3576055733210162 0.273185751006507 1.0601568587322105e-05 0.0022827689145391 1.0100053103379697e-05 1.972516813028553e-05 4.417853810010275e-05 +Mitochondria associated endoplasmic reticulum membrane 7 10 2.4703860584239776 0.0134967307555651 4.191747572815534 9.240291262135925 0.7019541594808174 0.4009163152547425 2.0831338076447135 1.0418560326821893 1.1194321867771957 0.3336055532093068 0.501059769155415 1.0 1.0 1.0 0.0098193480789534 +Proton transporting two sector atpase complex 7 23 2.4583939580654666 0.0139559985170569 7.116504854368932 22.25728155339806 1.0735578367707936 0.2848832687688338 3.2910616544032156 1.9833825153714253 1.32099194967518 0.2987458873835026 2.9979119853227453e-05 0.0115082778780227 0.0002983067426918 0.000144725329193 0.0001753252601336 +Late endosome membrane 13 38 2.456755189392045 0.0140198189400349 8.400485436893204 35.220873786407765 -0.1907871949509251 0.3412955054288843 4.360825137615114 6.285848739997517 1.5677242851178623 0.3272837423268039 0.006467721618025 0.4463627535095094 0.3281099840481742 0.0286791155023024 0.0023639052461662 +Cis golgi network 10 17 2.38055161145312 0.0172867392633502 5.446601941747573 14.91747572815534 1.304763677188147 0.2415633778835601 2.9087352716231463 3.2280604409731746 1.23405443481851 0.2890539664507128 0.0151318124703484 0.1715759324473242 0.3143397790261298 0.0678108138951911 0.0393164024746651 +Late endosome 23 68 2.3725978314200704 0.0176634847156789 15.655339805825244 65.18203883495146 0.1482522199608934 0.3683478922291265 6.675389202214119 9.543379127098556 1.7080817701484334 0.368772234437858 0.0048663996474158 0.6312378177493598 0.5898982141989131 0.0112054092519221 0.0009944931567881 +Vacuole 82 223 2.3272150594019294 0.0199538219055934 55.029126213592235 212.35679611650485 0.7895788564169173 0.4204713883128338 16.092847298969616 21.031446114270427 2.221429361906059 0.4148180554719883 6.446723965074731e-13 0.5166994793873827 0.007850577729461 1.9783983204888918e-10 2.1422321377037482e-13 +Calcium channel complex 3 7 2.24220477454579 0.0249481407217895 2.4150485436893203 7.298543689320389 0.1538765288718164 0.4525613292140901 1.4615016707365889 1.3130036030733032 1.08449347730351 0.3081575616966512 0.0101155059771168 0.1049896535105009 0.0202898922491691 0.0173886328284286 0.0234644839392777 +Secretory granule membrane 26 72 2.2318363080714927 0.0256257836820714 19.699029126213592 69.8495145631068 0.9295860214656708 0.3887665887416008 7.284889203542463 7.49087955205396 1.5950364553562375 0.3903287060113383 0.0013911830194275 0.5851156872439878 0.8286090733920952 0.0319784316416502 0.0001859444008344 +Cation channel complex 3 10 2.179853023117046 0.0292683580795649 2.5533980582524274 11.118932038834952 -1.1543889835844636 0.2437584715573 1.5515614142315322 2.1197020364986727 1.1909472972584103 0.2674128260769107 0.0785184637044285 0.187449079081247 0.0640285846884502 0.0854582473740603 0.1550661083475891 +Er to golgi transport vesicle membrane 11 23 2.171737750069757 0.0298754494079334 6.495145631067961 21.890776699029125 0.3958870084748403 0.5141628679854253 3.1618901389258056 2.1225127942575894 0.9657155478739712 0.3164691847513972 0.5005262433362921 1.0 1.0 1.0 0.0610180463767549 +Oxidoreductase complex 16 54 2.1504835414616243 0.0315169864886166 16.138349514563107 58.1747572815534 0.4112275970760134 0.4385210691837483 8.292749505639035 5.03902669070441 1.4297411393453454 0.366860872580609 0.0004545366182479 0.0128377566891277 0.0166529196858764 0.0032728763104503 0.0001141296100257 +Endoplasmic reticulum lumen 24 59 2.121331263186159 0.0338939352338927 18.07766990291262 59.737864077669904 0.9896277047863468 0.3946249358858228 7.513340007333169 6.273245958458151 1.4320597420402308 0.3846324865730224 0.0268509690384776 1.0 0.4855210477597627 0.2266833636016097 0.0176881426589972 +Nadh dehydrogenase complex 8 22 2.079290692934606 0.037590640051683 7.419902912621359 23.609223300970875 0.690247022635013 0.3818090321561181 3.6908298840900926 3.1049932192976284 1.21822710313397 0.3228613418826432 0.0013805381477328 1.0 0.3530974878629287 0.0230341265569123 0.0002619380543045 +Mib complex 7 10 2.04485179251794 0.0408694718261724 4.669902912621359 10.016990291262136 0.8674199579421746 0.3102009046029466 2.3929035436504367 0.6011337749949848 1.2568635951567688 0.31203902687269 0.0011015965796577 1.0 0.0066572828402184 0.003355333516566 0.0002481332774246 +Rough endoplasmic reticulum 12 39 2.044588029558343 0.0408954906356724 8.516990291262136 34.51699029126213 0.6279779058801568 0.506302031213321 4.715930723848554 2.6644372563657086 1.002611026388539 0.3540125587222381 0.0010040659956798 1.0 0.4129317333780675 0.000338442961232 5.512316207184221e-05 +Golgi apparatus subcompartment 36 92 2.0402524739135965 0.0413251857609977 23.898058252427184 88.56796116504854 0.6438651907142603 0.5157075238910589 9.044082768463602 13.85685287398648 1.2182273227220288 0.3801323692583779 0.0552347851538996 1.0 0.2676537229472664 0.1270039158258352 0.0736563093900414 +Coated vesicle 31 91 2.007491869214336 0.04469731552283 21.15776699029126 89.28398058252426 0.7996411773181966 0.4463095457932411 7.252509633536616 8.542551157088123 1.3406722753228342 0.3892656029628454 0.0093841859653417 0.2515369543584532 0.5790998686136157 0.0244236045811103 0.0042199282595296 +Membrane microdomain 19 56 1.9969749019135656 0.0458279094969842 14.75485436893204 63.49029126213592 0.5762129399877682 0.5023556315347317 6.545256989336744 6.436953608643344 1.167657055169838 0.3823949317010994 0.1184809072948666 0.2390350583825033 0.1165444039160723 0.0464115036719067 0.1508882561708747 +Micos complex 3 5 1.992590796870688 0.0463062737672483 2.4927184466019416 4.725728155339806 0.7557668283408772 0.3464970141803932 1.2077602589329477 0.4877312285913208 1.1862461875397572 0.3249829583805667 0.0026155774748029 1.0 0.0743799864466655 0.0148625463558957 0.0053334351931861 +Proton transporting atp synthase complex 4 12 1.9659891461018084 0.0492998643944764 4.157766990291262 11.08495145631068 0.5328143574617974 0.3012358599713604 2.3610641964760792 1.138499586439592 1.3748267965121657 0.2836171984539964 0.0003215953133908 0.0029386578360865 0.0005309775927247 0.0074273483269255 0.0010145405611514 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4965926e3969392eedead0e34fffd3986e3e9876 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 897, + "title": "Average number of proteins per term", + "value": 28.199554069119287 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..36d103dcd7d8755e4a51a7add1e5783896745bd6 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c09fa211e503753b3b8e17bb1856aef0883b949d --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,292 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Endoplasmic reticulum 0.5568752024369373 6.041124968003074 1.5304338241577403e-09 1.372798199928671e-06 1.372799141166493e-06 496 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243 +Intrinsic component of organelle membrane 0.6724901319821148 5.098536302753184 3.42289894196934e-07 0.000306986957501 0.0001535170175477 139 Q86Y82,Q86YN1,P98194,Q9H4I9,Q99595,Q9Y2R0,O60830,Q00325,P57105,Q9HCU5,Q9NPA0,Q9NZ01,Q9Y282,P51572,Q9BUR5,P04439,O14925,O75844,Q15070,Q5T9L3,P50416,Q9NQC3,Q10471,Q15041,Q13505,P10321,Q92643,O43752,Q96S52,Q14739,O95070,Q5XKP0,Q8TCT9,Q15629,Q9BUN8,Q5H8A4,P20020,Q9BTV4,Q9UG56,Q8N8Q8,Q9BPX6,Q96A33,Q9H3K2,O95470,Q16134,P12235,Q8IWA4,Q15388,Q9UM00,Q9NVH1,Q15125,Q9Y4P3,P42892,Q12981,Q9BWH2,Q8TCT8,Q9P035,Q16799,Q8N4V1,Q8TB61,O15118,Q9HC21,L0R6Q1,P57088,Q03518,Q9Y5U9,O76024,O75192,O15155,Q86XL3,Q16891,Q7L0J3,O15258,O43505,Q9Y6N1,Q6P4A7,Q9BUB7,P27824,O43826,O75880,O43808,Q9GZY8,Q53H12,P17152,Q15006,O94901,Q9Y512,Q9UH62,Q9NRB3,O96008,Q6ZRP7,Q5SNT2,Q99442,Q9Y5Y5,Q9NX63 95 +Organelle subcompartment 0.5964787355927148 4.847915244095302 1.247656810914376e-06 0.0011185228440212 0.0003730493864636 390 Q86YN1,O75122,P98194,P43307,Q9UGP8,Q99735,P49755,P09601,Q7Z2K6,Q9BQE5,Q92575,O60725,Q9Y6I9,O75396,P18031,O43909,P50402,Q5JRA6,Q9HCU5,O95197,Q9NPA0,Q14849,Q9NZ01,Q9NXE4,P30519,Q9BTU6,P24390,P26885,Q9Y282,Q9BRR6,Q9NPR9,P51572,Q9P2W9,O95674,Q9BUR5,O00400,P04439,Q9Y3B3,P51648,P15291,O75844,Q15005,Q5T9L3,P61019,Q9NQC3,Q8NBN3,P35610,O15127,Q96GC9,Q15363,O94905,O95864,Q10471,Q9NZ08,Q15041,Q9H4A6,Q9Y3A6,Q9H9E3,P10321,Q9HC07,O00461,Q96PC5,Q92643,Q12907,Q15800,O43752,O60762,Q9NP80,Q96S52,Q96S66,Q9Y320,Q14739,O95070,Q9H6H4,Q15042,Q8N0U8,Q8TCT9,Q15629,P05067,Q9BU23,Q9BUN8,Q7Z6M1,Q5H8A4,Q6NUK4,O43464,Q96G23,Q86SQ9,Q9BVC6,Q99720,Q15904,Q9Y6B6,Q86UE4,Q6NUQ1,Q70UQ0,Q9BV10,Q15392,Q8NHP6,Q96A57,Q6UX53,Q9BT22,P62942,Q8IV08,A1L0T0,Q96A33,O95470,P16435,Q9HD20,P04062,P67812,O00560,O14579,O95772,Q14534,Q07065,O43731,Q8N5M9,P07099,Q9NUQ2,Q9Y4P3,P00387,Q12981,Q9UBU6,Q96JJ7,Q8N511,Q99640,Q8TCT8,Q9P035,Q9Y5M8,P38435,P04844,Q8NHH9,Q10472,Q16799,Q8N4V1,Q8TB61,Q16850,Q96RQ1,Q96N66,Q14108,Q10713,Q06136,Q969V3,P57088,O00264,P61026,Q15382,Q03518,Q13190,Q9Y5U9,Q53GQ0,O76024,P51571,Q00765,Q9UKU0,Q96AG4,P16615,O15155,Q6NUQ4,O95249,Q86XL3,Q9H3N1,P46977,O43852,Q96HY6,Q96KC8,Q9BXS4,Q8TBA6,Q9HBH5,Q8TDW0,Q96L58,Q9Y394,Q9H2C2,P27824,P35613,O43826,Q9UBV2,Q8NF37,Q9H0U3,Q5VV42,Q9UEU0,O15269,Q15006,Q96HE7,Q9P246,P52292,O15260,P56962,Q4J6C6,O14653,Q9NX62,Q8N2F6,O00429,Q9NTJ5,P37268,Q6NUM9,Q99442,Q9Y5Y5,Q9H0U4 198 +Envelope 0.5046140809076533 4.759586671918012 1.939898097047532e-06 0.001738577201518 0.0004350221482631 480 O43169,Q9NS69,Q8N4H5,Q9H4I9,Q99595,P09601,Q9Y2R0,Q9H2W6,Q99735,O60830,O00584,Q92575,Q9NZ45,Q8WY22,P14406,Q9UDW1,Q9H2D1,P00846,P18031,P57105,P50402,Q00325,Q96B49,Q9H1E5,P41208,Q9NXE4,Q9BSK2,P80303,O14949,P24539,P62072,P45880,O95674,Q5T9A4,O60783,O43615,Q9BUR5,Q9BW27,P21912,O14925,O75844,Q9UBX3,Q70HW3,Q15070,Q9NVT9,Q9H061,Q9NVI7,P50416,Q9NQC3,Q9Y584,Q3ZCQ8,P0DP25,Q7Z7H8,O43592,O75964,Q96A26,Q8NFH5,Q9Y619,O43676,O14548,P21796,Q9H4A6,Q96TC7,Q13505,P67809,P56134,Q96CU9,Q9UJS0,Q12769,Q69YU5,Q9NP80,Q9Y277,Q9NQZ5,O15173,Q96S66,Q14739,Q9Y320,Q9Y371,Q9H2V7,Q96P70,Q5XKP0,P05067,P43304,O43464,Q99623,Q9BVC6,Q86Y39,Q99720,Q9NZJ7,P23786,Q86UE4,Q9BTV4,Q9UG56,P12236,Q15154,Q9UJZ1,Q8N8Q8,Q9H8M7,Q8NBN7,Q9Y6C9,O00165,Q9BPX6,Q9Y291,Q9HAV7,Q9H3K2,Q16134,P12235,Q96RL7,Q8IWA4,P40939,Q15388,Q96I36,O00560,P13073,Q567V2,P03886,Q9NVH1,Q9H936,Q15125,P06576,Q9NUQ2,O75431,P00387,Q12981,Q9BWH2,P42345,Q8IXM6,Q99523,Q9P0S9,Q9P035,Q9Y5J9,Q9BTX1,O95373,Q13423,P42167,O15118,Q14728,Q6DKK2,Q9HC21,O60220,O96000,Q96E52,Q9C0E2,Q10713,Q7KZN9,Q9P0J0,P52789,Q9BXK5,P57088,O75438,O00264,Q6NUK1,Q9NR28,P56378,O14657,Q8NFH4,Q9UKU0,Q96AG4,P56385,Q9HB71,Q9UDX5,Q7Z7F7,Q8IYU8,Q96KC8,Q16891,P82933,Q9BW72,Q96BR5,Q9Y6N1,P05141,Q6P4A7,Q8WUK0,Q9BUB7,O15397,O75880,Q9GZY8,Q53H12,P53701,P17152,O94901,Q9Y512,Q8N1F7,Q9UH62,Q07820,O60313,Q7Z3B4,O00429,O75306,Q9NPL8,Q6NUM9,O96008,O95202,O95168,O75027,Q6ZRP7,Q5SNT2,Q9NX63,Q96T37 198 +Inner mitochondrial membrane protein complex 0.6146164419174241 4.547073471649036 5.439701271203745e-06 0.0048675402545121 0.0009758824080541 75 Q99623,Q86Y39,Q99595,Q9H4I9,O96000,O60830,P12236,P14406,Q9UDW1,P00846,Q9P0J0,Q9BPX6,Q9HAV7,O14949,P24539,Q53H12,P62072,O75438,Q9BUR5,P21912,O14925,Q9Y512,P13073,P56378,P03886,Q9NVH1,Q9Y584,Q3ZCQ8,P06576,O75964,O43676,O14548,P56385,Q13505,O75306,P56134,Q8IYU8,Q96CU9,Q16891,O95168,Q9NX63,Q5XKP0 42 +Nuclear outer membrane endoplasmic reticulum membrane network 0.6109705550933442 4.499548896979371 6.809781523342551e-06 0.0060897765098405 0.0010180623377398 324 Q86YN1,P43307,Q9UGP8,Q99735,P49755,P09601,Q7Z2K6,Q9BQE5,Q92575,O60725,Q9Y6I9,O75396,P18031,O43909,P50402,Q5JRA6,Q9HCU5,O95197,Q9NPA0,Q14849,Q9NZ01,Q9NXE4,P30519,P24390,P26885,Q9Y282,Q9BRR6,P51572,Q9P2W9,O95674,Q9BUR5,O00400,P04439,Q9Y3B3,P51648,O75844,Q15005,Q5T9L3,P61019,Q9NQC3,P35610,Q96GC9,Q15363,O94905,O95864,Q10471,Q9NZ08,Q15041,Q9Y3A6,P10321,Q92643,Q96PC5,Q12907,Q15800,O60762,Q9NP80,Q96S52,Q96S66,Q9Y320,Q14739,O95070,Q9H6H4,Q15042,Q8N0U8,Q8TCT9,Q15629,Q9BU23,Q9BUN8,O43464,Q5H8A4,Q6NUK4,Q9BVC6,Q96G23,Q86SQ9,Q15904,Q99720,Q9Y6B6,Q86UE4,Q6NUQ1,Q70UQ0,Q9BV10,Q15392,Q8NHP6,Q9BT22,P62942,Q8IV08,A1L0T0,Q96A33,O95470,P16435,Q9HD20,P67812,O00560,O14579,O95772,Q14534,Q07065,O43731,Q8N5M9,P07099,Q9NUQ2,Q9Y4P3,P00387,Q12981,Q9UBU6,Q96JJ7,Q8N511,Q99640,Q8TCT8,Q9P035,Q9Y5M8,P38435,P04844,Q8NHH9,Q10472,Q16799,Q8N4V1,Q8TB61,Q16850,Q96RQ1,Q96N66,Q14108,Q06136,Q969V3,P57088,O00264,P61026,Q15382,Q03518,Q13190,Q9Y5U9,Q53GQ0,O76024,P51571,Q9UKU0,Q96AG4,P16615,O15155,Q6NUQ4,Q86XL3,Q9H3N1,P46977,O43852,Q96HY6,Q96KC8,Q9HBH5,Q8TDW0,Q9Y394,Q9H2C2,P27824,P35613,O43826,Q9UBV2,Q8NF37,Q9H0U3,Q5VV42,Q9UEU0,O15269,Q15006,Q96HE7,Q9P246,P52292,O15260,P56962,O14653,Q8N2F6,O00429,Q9NTJ5,P37268,Q6NUM9,Q99442,Q9Y5Y5,Q9H0U4 173 +Outer membrane 0.5824102466158917 4.454533012759663 8.40759922238199e-06 0.0075132813330542 0.0010773737860682 88 O43169,Q99623,Q9BVC6,Q9NS69,Q8N4H5,Q99720,P09601,Q9NZJ7,Q9NZ45,Q8WY22,P50402,P57105,Q9Y6C9,Q96B49,O00165,Q9NXE4,Q9GZY8,P52789,Q53H12,P45880,O00264,Q9BUR5,Q96RL7,Q8IWA4,Q15388,Q9Y512,Q9NVT9,P50416,Q9NVH1,Q9UH62,Q07820,O60313,O75431,Q9NUQ2,P00387,Q9UKU0,O00429,P42345,P21796,Q9BWH2,Q96TC7,Q13505,Q6NUM9,Q16891,O96008,Q9Y277,Q9NQZ5,Q9Y371,Q9NX63,Q5XKP0 50 +Intrinsic component of plasma membrane 0.5993009024015091 4.312861964829129 1.6115474027245114e-05 0.014351714746434 0.0018069475253049 73 O43464,O43657,P11279,P20020,P05141,P27824,P35613,Q9UIQ6,Q00325,Q9BTU6,Q9H0U3,Q99805,P12235,P51572,O00264,P17152,P04439,O00400,Q08722,P27105,Q9NR28,O00560,Q99808,Q99797,P0DP25,P16615,O95864,Q8WTV0,Q92542,P10321,P05067,Q12907,Q9UJS0,P05023,Q9Y639,O96005,Q8TDW0,Q9H1Z9,P55011,O15118 40 +Intrinsic component of endoplasmic reticulum membrane 0.6606204657193797 4.2566974121822465 2.074688462139207e-05 0.0184380489957899 0.0020677728339321 54 Q9BUN8,Q86YN1,Q5H8A4,P27824,O43826,Q9HCU5,Q9NPA0,Q9NZ01,Q96A33,Q9Y282,O95470,P57088,P51572,P04439,Q15006,Q03518,O75844,Q9NQC3,O76024,Q9Y4P3,Q12981,Q15041,Q86XL3,Q8TCT8,Q9P035,Q92643,P10321,Q16799,Q99442,Q8N4V1,Q8TB61,Q8TCT9,Q15629 33 +Intrinsic component of mitochondrial membrane 0.6639164727490702 4.213745049432649 2.5117079742731363e-05 0.0222783916209661 0.002253002052923 51 Q9HC21,Q9H4I9,Q99595,Q9Y6N1,Q9Y2R0,Q6P4A7,O60830,Q9BUB7,Q9UG56,Q8N8Q8,O75880,Q00325,P57105,Q9BPX6,Q9H3K2,Q9GZY8,Q53H12,Q16134,P12235,P17152,Q9BUR5,Q8IWA4,Q15388,O14925,Q9Y512,Q15070,P50416,Q9NVH1,Q9UH62,O75431,Q9BWH2,Q13505,O96008,Q16891,Q9NX63,Q5XKP0 36 +Lysosomal lumen 0.7180083166040151 4.137662686558398 3.508616653569163e-05 0.0309827288019941 0.0028611173984105 36 P07602,O00584,Q9NZJ7,Q99538,Q14108,P46976,P10253,P50897,O14773,P61916,Q8IV08,P08236,P11117,P06280,P16278,P17900,P04062,Q13510,P15586,P04066,P10619,Q9UMR5,P38435,Q8NHP8,P06865,Q9UM22,P54802 27 +Mitochondrion 0.357051394425924 4.049196194288579 5.1393847016578675e-05 0.0450549366555799 0.0038416900644893 596 O43169,Q9NS69,Q8N4H5,Q9H4I9,Q99595,P09601,Q9Y2R0,Q9H2W6,O00584,O60830,Q8NBX0,Q9NZ45,Q8WY22,P14406,Q9UDW1,Q9H2D1,P00846,P18031,P57105,Q3SXM5,Q9UIJ7,Q00325,Q96B49,Q14849,Q9BSK2,Q9BTU6,Q8NCN5,O14949,P24539,P62072,Q96RR1,P45880,P51572,O95674,O60783,Q5T9A4,Q9BUR5,O43615,P21912,O14925,Q9NVT9,Q9UBX3,Q70HW3,Q15070,Q9NVI7,Q9H061,Q99797,P50416,Q9Y584,Q3ZCQ8,P0DP25,Q7Z7H8,Q15165,O75964,Q96A26,Q9NPH0,Q9Y619,O43676,P21796,Q13505,Q96CU9,Q69YU5,Q9NP80,Q9Y277,Q9NQZ5,Q9NUQ9,Q5XKP0,Q86Y39,Q9H773,Q9NZJ7,P23786,Q9UG56,P12236,Q8N8Q8,Q8NBN7,Q9Y6C9,Q9NUL7,Q9H3K2,Q9H6K4,P12235,P16435,P27105,Q96I36,P13073,Q567V2,P03886,P28070,Q9NUQ2,P00387,Q12981,Q9BWH2,P00374,O43708,Q5JRX3,Q9BWD1,Q9Y5J9,Q05655,Q16836,Q13423,Q6DKK2,Q9HC21,O60220,O96000,Q96E52,Q10713,Q7KZN9,Q9P0J0,P52789,Q9BXK5,O75438,O00264,Q9NUJ1,Q6NUK1,Q9NR28,Q9BW92,P56378,Q5T2R2,Q9UKU0,Q9NVH6,Q96AG4,O15091,P56385,Q9UDX5,Q92542,Q7Z7F7,Q8IYU8,P48723,Q16891,P82933,Q8IVS2,Q9BW72,Q96BR5,Q9Y6N1,P05141,Q6P4A7,Q8WUK0,Q9BUB7,Q07021,P35613,O75880,P51530,Q9GZY8,Q53H12,P53701,P17152,Q9Y512,P13674,P56962,Q8IXJ6,Q9UH62,Q07820,O60313,Q8N2F6,O00429,O75306,Q9NPL8,Q16740,O96008,O95202,O95168,O75027,Q9NX63 162 +Intrinsic component of mitochondrial inner membrane 0.7151040571923621 4.011012488074693 6.045891191508446e-05 0.0527888879476343 0.0041716649221408 34 Q9HC21,Q9H4I9,Q99595,Q9Y6N1,Q9Y2R0,Q6P4A7,O60830,Q9UG56,Q8N8Q8,O75880,Q9H3K2,Q53H12,P17152,Q9BUR5,Q9Y512,O14925,Q15070,Q13505,Q16891,Q9NX63,Q5XKP0 21 +Endoplasmic reticulum golgi intermediate compartment membrane 0.7333111113811873 3.9068575535876833 9.350423896803406e-05 0.0804558527481905 0.0055915534902884 29 Q15904,P49755,Q96RQ1,O75396,P24390,Q9Y282,P51572,Q9Y3B3,Q03518,Q13190,O15260,P61019,P56962,O14653,Q96GC9,Q15363,O15155,Q8N511,Q9Y3A6,Q12907,Q10472,O95070,Q9H0U4 23 +Transporter complex 0.6054490152059658 3.7822609955387425 0.0001554102869718 0.1301320503529422 0.0083993415703625 54 Q86Y39,O60220,Q9H4I9,O96000,Q9UDW1,P62942,Q9P0J0,O14949,Q9C0H2,P62072,O75438,O75381,P03886,P0DP25,O43676,Q86WC4,O75306,Q8IYU8,Q96CU9,O95168,Q9Y5J9,Q8TDW0 22 +Golgi membrane 0.5489594383308599 3.77628499222241 0.0001591848458151 0.1330727127677583 0.0083993415703625 138 Q86Y82,O15258,O43505,P98194,Q8IZA0,Q96L58,P49755,L0R6Q1,Q14108,O75396,P35613,Q10713,Q15392,O95197,Q8IV08,Q8NF37,Q9NXE4,Q08AM6,P24390,Q9Y282,P51572,Q9P2W9,Q8TBQ9,Q9BUR5,P04439,O00400,Q9Y3B3,P61026,Q8NCH0,Q15382,P15291,O14579,P52292,Q5T2E6,Q13190,Q5T9L3,P61019,Q9Y5U9,O15260,O43731,Q8NBN3,O14653,Q15363,O15155,O95721,O95249,Q10471,Q99640,Q9H4A6,Q9NTJ5,Q92896,Q9H9E3,Q9NRB3,Q7LGA3,P10321,Q9HC07,O00461,Q12907,Q9BXS4,Q8TBA6,O43752,Q10472,Q16799,Q96S66,Q6ZRP7,O95070,Q8N4V1,Q8TB61,Q9H0U4 69 +Organelle inner membrane 0.569228055032935 3.739743452165732 0.0001842081641418 0.1523181952861373 0.009179706846404 241 Q9H2W6,Q9H4I9,Q99595,Q9Y2R0,O60830,P18031,P14406,Q9UDW1,P50402,Q9H2D1,Q00325,P00846,Q9H1E5,Q9BSK2,O14949,P24539,P62072,O95674,Q5T9A4,O60783,O43615,Q9BUR5,P21912,O14925,O75844,Q9UBX3,Q70HW3,Q15070,Q9NVI7,Q9H061,Q9Y584,Q3ZCQ8,Q7Z7H8,O75964,Q9Y619,O43676,O14548,Q13505,P56134,Q9UJS0,Q96CU9,Q69YU5,Q14739,Q9H2V7,Q5XKP0,P43304,Q99623,Q86Y39,Q99720,P23786,Q9BTV4,Q9UG56,P12236,Q9UJZ1,Q8N8Q8,Q8NBN7,Q9Y6C9,Q9BPX6,Q9Y291,Q9HAV7,Q9H3K2,Q16134,P12235,P40939,P13073,Q567V2,Q9NVH1,P03886,Q9H936,P06576,Q8IXM6,Q9Y5J9,Q13423,Q14728,Q6DKK2,Q9HC21,O60220,O96000,Q96E52,Q10713,Q7KZN9,Q9P0J0,O75438,Q6NUK1,P56378,P56385,Q9UDX5,Q7Z7F7,Q8IYU8,Q16891,P82933,Q9BW72,Q9Y6N1,P05141,Q6P4A7,Q8WUK0,Q9BUB7,O75880,Q53H12,P53701,P17152,O94901,Q9Y512,O60313,O75306,Q9NPL8,O96008,O95202,O95168,O75027,Q5SNT2,Q9NX63 112 +Mitochondrial envelope 0.5569004246404492 3.724458495995202 0.0001957349095567 0.1610392865987501 0.0092407480985458 313 O43169,Q9NS69,Q8N4H5,Q9H4I9,Q99595,P09601,Q9Y2R0,Q9H2W6,O00584,O60830,Q9NZ45,Q8WY22,P14406,Q9UDW1,Q9H2D1,P00846,P18031,P57105,Q00325,Q96B49,Q9BSK2,O14949,P24539,P62072,P45880,O95674,Q5T9A4,O60783,O43615,Q9BUR5,P21912,O14925,Q9NVT9,Q9UBX3,Q70HW3,Q15070,Q9NVI7,Q9H061,P50416,Q9Y584,Q3ZCQ8,P0DP25,Q7Z7H8,O75964,Q96A26,Q9Y619,O43676,O14548,P21796,Q9H4A6,Q96TC7,Q13505,P56134,Q96CU9,Q9UJS0,Q69YU5,Q9NP80,Q9Y277,Q9NQZ5,Q9Y320,Q9Y371,Q9H2V7,Q5XKP0,P43304,O43464,Q99623,Q86Y39,Q9NZJ7,P23786,Q9UG56,P12236,Q9UJZ1,Q8N8Q8,Q8NBN7,Q9Y6C9,O00165,Q9BPX6,Q9Y291,Q9HAV7,Q9H3K2,Q16134,P12235,Q96RL7,Q8IWA4,P40939,Q15388,Q96I36,P13073,Q567V2,P03886,Q9NVH1,Q9H936,P06576,Q9NUQ2,O75431,P00387,Q12981,Q9BWH2,P42345,Q9P0S9,Q9Y5J9,Q13423,Q6DKK2,Q9HC21,O60220,O96000,Q96E52,Q10713,Q7KZN9,Q9P0J0,P52789,Q9BXK5,O75438,O00264,Q6NUK1,Q9NR28,P56378,Q9UKU0,P56385,Q9UDX5,Q7Z7F7,Q8IYU8,Q16891,P82933,Q9BW72,Q96BR5,Q9Y6N1,P05141,Q6P4A7,Q8WUK0,Q9BUB7,O75880,Q9GZY8,Q53H12,P53701,P17152,Q9Y512,Q9UH62,Q07820,O60313,O00429,O75306,Q9NPL8,O96008,O95202,O95168,O75027,Q9NX63 148 +Exocytic vesicle 0.6038740314013558 3.55498261863459 0.0003780040770782 0.2876128448715839 0.0169534828569582 42 Q15907,Q9BT78,P11279,Q9GZY8,O76024,O43760,P0DP25,O43752,Q13277,Q9UEU0,Q7L0J3,P61026,O00429,Q96A57,P50897,Q92542,P05067,O15400 18 +Vacuolar lumen 0.5428410543267312 3.5390704322411897 0.0004015387028493 0.3024998491176131 0.0171514388788492 67 P07602,O00584,Q9NZJ7,Q99538,Q14108,P46976,P10253,O14773,Q9BTY2,P50897,Q8IV08,P61916,P08236,Q92820,P11117,P06280,P16278,P17900,P04062,Q13510,O00560,P15586,P04066,O00754,P00387,P10619,Q9UMR5,P38435,Q8NHP8,Q05655,P06865,Q9UM22,P54802 33 +Endoplasmic reticulum golgi intermediate compartment 0.5699014426620883 3.404344109324762 0.0006632314493841 0.4485014016071204 0.0252819231737858 51 O15258,P49755,Q96RQ1,O75396,Q02818,P80303,P24390,Q9Y282,P51572,P07237,Q9Y3B3,Q03518,Q13190,O15260,P61019,P56962,O14653,Q96GC9,Q15363,O15155,Q8N511,Q9Y3A6,Q12907,Q10472,O95070,Q9H0U4 26 +Golgi cisterna 0.6866333311736885 3.398954609186573 0.000676439416021 0.4550010816697832 0.0252819231737858 25 P98194,Q96L58,Q9Y6B6,Q10713,P51572,P04439,P15291,Q8NBN3,Q15363,Q9Y3A3,O15155,O95249,Q99523,Q10471,Q9H4A6,O00461,Q9BXS4,Q8TBA6,Q10472 19 +Respirasome 0.5816991001400252 3.367790638354007 0.0007577311323143 0.4933538585963684 0.0271873930274394 42 Q9P0J0,O75306,Q6DKK2,P03886,O14949,Q86Y39,Q96CU9,O96000,O75438,O95168,O43676,P14406,Q9UDW1,Q7KZN9,P21912,P13073,Q9BW72,Q13423 18 +Organelle membrane contact site 0.7336452107658777 3.313297176589411 0.0009220295430605 0.5628338812880354 0.0318100192355883 19 Q14849,O95772,Q676U5,P56962,O96008,Q96N66,P51572,P27824,Q96S66,Q9Y320,Q8NHP6,Q9NTJ5,Q5XKP0,Q96TC7 14 +Transport vesicle 0.4838164455830241 3.2840188057049056 0.0010233809336663 0.6008598761259338 0.0332364602650221 98 Q86Y82,Q15907,P11279,P49755,P20020,O75396,Q96A57,P50897,Q9NR31,P24390,Q9GZY8,Q9UEU0,P04439,P61026,Q9Y3B3,O14579,Q13190,O15400,O15260,P56962,O43731,O76024,P0DP25,O14653,Q15363,O15155,O00429,O95249,O43760,Q92542,P10321,O00461,Q9BT78,Q8TBA6,O43752,Q13277,Q7L0J3,Q7Z6M1,Q9H0U4,P05067 40 +Copii coated er to golgi transport vesicle 0.6160955553665288 3.2757727922105375 0.0010537329580444 0.6115911693532224 0.0332364602650221 34 P49755,Q96RQ1,Q9Y6B6,O75396,Q9NR31,Q9Y282,Q9UEU0,P04439,Q9Y3B3,Q13190,Q9Y5U9,P56962,O14653,Q15363,Q9Y3A6,P10321,Q12907,O95070,P05067 19 +Intrinsic component of golgi membrane 0.8054821664464904 3.0923910558554795 0.0019855109840893 0.8318289726497442 0.0543166986551676 12 O15258,Q9Y5U9,O43505,P98194,Q9Y282,L0R6Q1,O15155,Q6ZRP7,O95070,Q9NRB3,Q8TB61 11 +Vacuolar membrane 0.4851384181766072 3.090488831808348 0.0019982731946717 0.8337469657458689 0.0543166986551676 127 P11279,P07602,Q9NZJ7,O60784,Q9Y6I9,Q14108,Q9UIQ6,P10253,Q8NF37,Q8IV08,Q14849,Q08AM6,P11117,Q9H0U3,Q9UEU0,P04062,P27105,Q15382,O75503,O95772,O15400,Q676U5,O15260,Q07065,Q96GC9,P42892,Q93050,Q86WC4,P10619,Q8N511,Q9Y487,Q8TCT8,Q8WTV0,Q9Y2T2,Q92542,Q9HC07,P04844,Q9BXS4,Q8NCG7,Q9HBH5,O15118 41 +Azurophil granule 0.4805332092914939 3.0769706276707094 0.0020911590545384 0.8470636835813845 0.0551696962329714 73 P11279,P07602,O00584,Q9NZJ7,O60784,P10253,Q9BTY2,P61916,Q8NF37,P08236,Q92820,P06280,Q9H0U3,P16278,P17900,P27105,Q13217,O00560,P15291,P53634,P15586,O15400,O15260,O43681,Q07065,P04066,O00754,Q9BRF8,P00387,P10619,O95721,Q9H7Z7,Q92542,P42785,Q13277,Q05655,P06865 37 +Golgi cisterna membrane 0.6923048172990578 3.056598989961432 0.0022386354825447 0.8660524589887773 0.0573730293669331 19 O00461,P98194,Q96L58,Q8NBN3,Q9Y6B6,P51572,Q15363,Q9Y3A3,Q99523,Q10472,Q10713,Q9H4A6,Q10471,P15291 14 +Snare complex 0.6709501849312182 3.0307849660163892 0.002439188941667 0.8881532046254071 0.0607764577965375 21 Q86Y82,P56962,O15400,O14653,O43752,Q9P2W9,Q13277,O75396,Q9UEU0,Q12981,O15155,O95249,Q13190 13 +Transport vesicle membrane 0.5320262798348577 2.981659796328795 0.0028669038619217 0.9238694849351082 0.06858471286987 46 Q86Y82,Q15907,P20020,P49755,O75396,Q9NR31,Q9UEU0,P04439,Q9Y3B3,Q13190,P56962,O76024,P0DP25,O14653,Q15363,O00429,O43760,P10321,O43752,Q7L0J3 20 +Cytochrome complex 0.7168504562781008 2.914411221216296 0.0035636015076263 0.9593298038481576 0.077842839187593 15 P13073,P14406,Q9UDW1,O14949 4 +Endoplasmic reticulum tubular network 0.7391968004087173 2.905105493508678 0.003671293379508 0.9630876855224146 0.077842839187593 13 Q6NUK4,Q9NQC3,Q00765,Q8NHH9,Q9H2C2,P61026,P50402,Q9H6H4 8 +Microbody membrane 0.6154799784832722 2.902518823183546 0.0037017491332305 0.9640860670041432 0.077842839187593 25 Q8TB36,O43808,Q7Z434,P40855,O00116,Q9UKU0,Q9NP80,Q15067,O75192,Q9Y5Y5,P50542,Q8NBU5,P51648,P28288,O75381 15 +Membrane protein complex 0.5029686972967569 2.8964461233174355 0.0037741544183769 0.9663526566503332 0.077842839187593 283 Q86Y82,Q9NS69,Q9UGP8,Q9H4I9,P49755,Q8N4H5,Q99595,O60830,O75396,P14406,Q9UDW1,P00846,Q9NPA0,O14949,Q9C0H2,P24539,P62072,P45880,Q9P2W9,Q9BUR5,P04439,Q9Y3B3,P21912,O14925,Q15005,Q9Y584,Q3ZCQ8,P0DP25,O75964,O43676,Q86WC4,O95721,O14548,P21796,Q15041,Q9Y487,Q13505,P10321,Q92643,P56134,Q96CU9,Q8NEB9,O43752,Q9Y277,Q96S52,Q96S66,Q5XKP0,Q8TCT9,O43464,Q9BUN8,Q99623,Q86Y39,Q15904,Q9Y6B6,P12236,P62942,Q9BPX6,Q08AM6,Q9HAV7,P12235,Q8IWA4,P67812,Q15388,P53680,O00560,P13073,O14579,Q9NVH1,P03886,P54709,P06576,O75431,Q07666,Q12981,Q93050,Q9UBU6,P49458,Q8N511,Q9Y2T2,Q9Y5M8,P04844,Q8N4V1,O96000,Q9NR31,Q9P0J0,O75438,Q9NR28,Q03518,P56378,Q13190,Q53GQ0,P51571,O15155,O95249,P56385,Q92542,P46977,Q8IYU8,Q16891,Q13277,Q8TDW0,P05141,Q9UBV2,P63218,Q9H0U3,Q53H12,Q9UEU0,O15269,Q15006,O94901,Q9Y512,O15400,P56962,O14653,Q9P253,O75306,O96008,O95168,P05023,Q9NX63 120 +Outer mitochondrial membrane protein complex 0.7006627089921076 2.8927889450293227 0.0038183778419778 0.9676661546008362 0.077842839187593 16 Q13505,Q9NVH1,Q9NS69,Q8N4H5,O96008,Q16891,Q9BUR5,Q8IWA4,Q15388,Q9NX63,Q9Y512,Q5XKP0 12 +Nuclear inner membrane 0.6467674702898358 2.870747242843826 0.0040950281618654 0.974796738497086 0.0798530491563766 21 Q14728,Q99720,Q5SNT2,Q14739,O94901,Q8IXM6,O75844,Q9H1E5 8 +Mitochondrial protein containing complex 0.4755612027199148 2.810181711805588 0.0049513536187733 0.9883493814782364 0.0906400856334622 154 Q9NS69,Q8N4H5,Q9H4I9,Q99595,Q86Y39,O60220,O96000,P05141,O60830,P12236,P14406,Q9UDW1,P00846,Q9P0J0,O14949,P24539,P62072,P12235,O75438,Q53H12,O60783,Q9BUR5,O14925,Q9Y512,P13073,P56378,Q567V2,P03886,Q9Y584,Q7Z7H8,O75964,O43676,P21796,O15091,P56385,Q13505,O75306,Q7Z7F7,Q8IYU8,Q96CU9,Q16891,O96008,O95168,Q9Y5J9,P82933,Q9NX63,Q5XKP0 47 +Azurophil granule membrane 0.6030051521954686 2.747174571340241 0.0060111129780455 0.9955204802836374 0.0929649714018427 24 O15260,Q07065,P11279,Q9H0U3,P07602,Q9NZJ7,P42785,O60784,P10253,P27105,O95721,P15291,Q92542,Q8NF37 14 +Endoplasmic reticulum protein containing complex 0.4783543287496044 2.699407203880937 0.0069463124774422 0.998074527181464 0.1031578021315429 60 Q9BUN8,Q9UGP8,Q6NUQ1,Q9UBV2,Q9NPA0,P62942,Q9H0U3,P04439,P07237,Q15006,O15269,P67812,Q03518,P13674,Q15005,O43681,Q53GQ0,P51571,Q9UBU6,P49458,Q15041,P46977,Q9Y5M8,Q92643,P04844,Q96S52,Q8N4V1,Q8TCT9 28 +Ion channel complex 0.6541752042599098 2.6829203273537554 0.0072982374896015 0.9985989382336632 0.1055890165834291 17 Q8IYU8,Q9H4I9,P0DP25,Q9C0H2,Q86WC4,P62942 6 +Tim23 mitochondrial import inner membrane translocase complex 0.8681688980512823 2.6630027763165174 0.0077446775139933 0.9990641136206884 0.1058479437852137 7 Q99595,O14925,P62072,O60830 4 +Respiratory chain complex iii 0.8679612393423606 2.6620723183146153 0.0077661191086624 0.9990820796310512 0.1058479437852137 7 Q9UDW1 1 +Intrinsic component of mitochondrial outer membrane 0.6963951825745818 2.6611189840287706 0.0077881430209856 0.9991001749563608 0.1058479437852137 13 O95140,P50416,Q9UH62,Q9GZY8,O96008,Q8IWA4,Q9BWH2,Q15388,P57105 9 +Synaptic vesicle membrane 0.6461329821942459 2.6318699042434037 0.0084916372097461 0.9995237288520292 0.1103912837266993 17 Q15907,O76024,P0DP25,O43752,Q7L0J3,O00429,O43760 7 +Specific granule membrane 0.6328583228597301 2.6251954598661427 0.0086599238682447 0.9995909945590794 0.1109707387116508 18 P30519,Q07065,P61225,O60784,Q08722,P27105 6 +Golgi stack 0.5219348794650389 2.553035940983861 0.0106788476128691 0.9999343018188608 0.1261386988763469 35 P98194,Q96L58,Q9Y6B6,Q10713,P51572,Q7L5N7,P04439,P15291,Q8NBN3,Q15363,Q9Y3A3,O15155,O95249,Q10471,Q99523,Q9H4A6,O00461,Q9BXS4,Q8TBA6,Q10472 20 +Proton transporting two sector atpase complex proton transporting domain 0.7497121889802746 2.5027630541794803 0.0123228012654461 0.9999852198105368 0.1347004084578546 10 P24539,O75964,Q93050,P00846,Q9Y487 5 +Mitochondria associated endoplasmic reticulum membrane 0.7434589003744634 2.4703860584239776 0.0134967307555651 0.9999949139530966 0.1375746305425217 10 P56962,O96008,Q96N66,P51572,P27824,Q96S66,Q9Y320 7 +Proton transporting two sector atpase complex 0.5713740147917179 2.4583939580654666 0.0139559985170569 0.9999966505229037 0.1375760828081255 23 P24539,Q9Y487,O75964,Q93050,P00846,Q8N511,P56378 7 +Late endosome membrane 0.4964588145603403 2.456755189392045 0.0140198189400349 0.999996839452731 0.1375760828081255 38 Q14849,Q08AM6,O95772,Q9HC07,P11279,Q9BXS4,O14653,Q14108,Q9UEU0,Q96SU4,Q8TCT8,Q8IV08,O15118 13 +Cis golgi network 0.6072551500727603 2.38055161145312 0.0172867392633502 0.9999998389894376 0.1566283345376278 17 O00461,P98194,O43731,P24390,P49755,Q8WVM8,Q9NPR9,Q8TBA6,O95249,Q9Y3A6 10 +Late endosome 0.4311997511999124 2.3725978314200704 0.0176634847156789 0.9999998858493911 0.1568727305937028 68 Q9BUN8,P11279,P07602,Q9NZJ7,Q99538,Q14108,Q96A57,Q8IV08,Q14849,Q08AM6,Q9UEU0,Q96PU5,O15400,O95772,O14653,Q8TCT8,Q9P253,Q9HC07,Q8NEB9,Q9BXS4,Q9BRK5,Q96SU4,O15118 23 +Vacuole 0.4596141929644367 2.3272150594019294 0.0199538219055934 0.9999999859348028 0.1721017139357437 223 O00584,Q99538,Q9Y6I9,P46976,P50897,Q9BTY2,Q9P2J5,Q14849,Q9BTU6,Q9UHD9,Q13510,P15291,Q676U5,P61019,P04066,O00754,Q15165,Q9BRF8,Q96GC9,Q86WC4,P10619,Q9Y487,Q9UMR5,Q9HC07,Q8NEB9,Q9NZJ7,Q9UHG3,Q96A57,Q8IV08,Q08AM6,Q9NX40,P17900,P04062,P27105,O00560,P15586,O75503,O95772,Q07065,P00387,P42892,Q93050,Q8N511,Q8TCT8,Q8WTV0,Q9Y2T2,P38435,P04844,Q969Q5,Q8NCG7,Q8NHP8,Q05655,P06865,Q9UM22,O15118,P11279,P07602,O60784,Q14108,Q9UIQ6,O14773,P08236,P11117,P06280,P16278,Q15382,Q92542,Q9BXS4,Q13277,Q9HBH5,P54802,P10253,P61916,Q8NF37,Q92820,Q9H0U3,Q8NCC3,Q9UEU0,O15400,O15260,P56962,Q9P253 82 +Calcium channel complex 0.7766376919405256 2.24220477454579 0.0249481407217895 0.9999999998561664 0.2016079479950018 7 P0DP25,P62942,Q9H4I9 3 +Secretory granule membrane 0.4100578506659303 2.2318363080714927 0.0256257836820714 0.9999999999229048 0.2052350710965902 72 P11279,P49755,P07602,Q9NZJ7,O60784,P35613,P10253,Q8NF37,P30519,Q9H0U3,O00264,Q5T9A4,Q08722,P61026,P27105,P15291,O15260,Q07065,P61225,Q15363,Q93050,Q96JJ7,O95721,Q92542,Q969Q5,Q13277 26 +Cation channel complex 0.688441706560216 2.179853023117046 0.0292683580795649 0.999999999997321 0.2302957648892085 10 P0DP25,P62942,Q9H4I9 3 +Er to golgi transport vesicle membrane 0.5326540595622388 2.171737750069757 0.0298754494079334 0.9999999999984716 0.2310196389561747 23 P10321,P56962,P49755,O14653,Q15363,O75396,P04439,Q9UEU0,Q9Y3B3,Q9NR31,Q13190 11 +Oxidoreductase complex 0.4359405567719338 2.1504835414616243 0.0315169864886166 0.9999999999996654 0.2355894740024096 54 O43169,Q9P0J0,O75306,P03886,P31350,O14949,Q86Y39,Q96CU9,O96000,O75438,O95168,P00387,O43676,P07237,Q9UDW1,P13674 16 +Endoplasmic reticulum lumen 0.4258849036243926 2.121331263186159 0.0338939352338927 0.999999999999963 0.2471777228032664 59 O75718,O00584,Q9BTV4,P27824,Q9BV10,Q5JRA6,Q02818,Q9BTY2,Q14257,Q8TED1,Q9Y680,P07237,Q13217,P53634,Q96HE7,Q9NWM8,P13674,O43681,Q07065,O76024,O14657,Q9NZ08,O43852,P05067 24 +Nadh dehydrogenase complex 0.5271820473811853 2.079290692934606 0.037590640051683 0.9999999999999988 0.2634281572371847 22 Q9P0J0,O75306,P03886,Q96CU9,Q86Y39,O96000,O75438,O43676 8 +Mib complex 0.663521214966082 2.0448517925179397 0.0408694718261724 1.0 0.2729972738169385 10 Q13505,Q9NVH1,Q16891,Q9BUR5,Q9NX63,Q9Y512,Q5XKP0 7 +Rough endoplasmic reticulum 0.4472835830325661 2.044588029558343 0.0408954906356724 1.0 0.2729972738169385 39 Q9Y5M8,Q96A33,P56962,Q07065,P04844,Q9HD47,P51571,Q5VV42,P27824,Q99442,Q8TCT9,P05067 12 +Golgi apparatus subcompartment 0.3805206734793688 2.0402524739135965 0.0413251857609977 1.0 0.2729972738169385 92 O75122,P98194,Q96L58,Q9Y6B6,Q10713,Q96A57,P40616,Q9NXE4,Q9BTU6,Q9NPR9,P51572,Q7L5N7,P04439,P04062,P61026,P15291,Q5T9L3,Q4J6C6,Q8NBN3,O15127,Q9NX62,Q15363,Q9Y3A3,O15155,O95249,Q10471,Q9H4A6,Q9H9E3,Q9HC07,O00461,Q9BXS4,Q8TBA6,O43752,Q10472,Q7Z6M1,P05067 36 +Coated vesicle 0.3773611357073833 2.007491869214336 0.04469731552283 1.0 0.2803740700977523 91 P49755,Q96RQ1,Q9Y6B6,Q14108,O75396,Q9NR31,O00165,P24390,Q9Y282,P51572,Q9UEU0,P04439,Q9Y3B3,P53680,O14579,Q13190,Q9Y5U9,P56962,O43731,O14653,Q15363,P42892,Q8N511,Q9Y3A6,Q9P253,P10321,Q12907,Q5VW38,O43752,O95070,P05067 31 +Membrane microdomain 0.418872458978975 1.9969749019135656 0.0458279094969842 1.0 0.2815591425944853 56 Q86Y82,P20020,P09601,P05141,P35613,P50897,O14773,Q9BTU6,P27105,O00560,Q9HD47,P61225,P10644,O94905,P21796,Q8WTV0,P05023,P05067,O15118 19 +Micos complex 0.7916548593777312 1.9925907968706875 0.0463062737672483 1.0 0.2825627725797401 5 Q9BUR5,Q16891,Q5XKP0 3 +Proton transporting atp synthase complex 0.6045582796107274 1.9659891461018084 0.0492998643944764 1.0 0.2987971510935497 12 P24539,P56378,O75964,P00846 4 +Ciliary transition zone 0.7151716047399075 1.9473689221452797 0.0514905211501315 1.0 0.3099798488031408 7 Q15555,A6NIH7,Q92845,P41208 4 +Proton transporting atp synthase complex coupling factor f o 0.7144065656819529 1.9436372532840431 0.0519392101331503 1.0 0.3105964765962393 7 P24539,O75964,P00846 3 +Organelle envelope lumen 0.4317840614425779 1.9372862131418491 0.0527103666102204 1.0 0.3131205221812433 40 O43464,P05067,Q96BR5,Q8IYU8,O60220,O00584,Q53H12,P62072,O60313,Q16891,Q9Y5J9,Q9UJZ1,Q9NR28,O14925,Q9H4A6,Q9HB71,O00165 17 +Lumenal side of membrane 0.6426632237768939 1.9302208534933964 0.053579478766786 1.0 0.3141228264954711 10 P51572,P27824,Q8TCT9,P04439,P10619,Q8TCT8 6 +Caveola 0.5665560571030644 1.9256488731379793 0.0541482318113231 1.0 0.31467596423788 14 P09601,Q9HD47 2 +Pore complex 0.703939867758291 1.923833592141712 0.0543754453253861 1.0 0.31467596423788 8 P05141,P12235,P45880,Q9Y277,P21796 5 +Integral component of synaptic vesicle membrane 0.707447549114578 1.909623995297823 0.0561816433157895 1.0 0.32304444906579 7 Q86Y82,O76024,P20020,O43752,Q7L0J3 5 +Cytoplasmic ubiquitin ligase complex 0.7239138048206042 1.8972124438744256 0.0577999051464803 1.0 0.330232579085305 6 Q9BUN8,Q9UBU6 2 +Lipid droplet 0.4501558825848816 1.8853769939936456 0.0593789578082672 1.0 0.3361149307263573 34 Q07065,Q99720,P51572,Q7L5N7,Q8NBX0,P00387,Q01105,Q9H6V9,Q6UX53,O43760,Q8NBQ5,Q15042,Q8NF37 13 +Golgi lumen 0.7673136452354726 1.8838970617435904 0.0595789007642038 1.0 0.3361149307263573 5 O00461,Q9NX62,P05067 3 +Phagocytic vesicle membrane 0.494561265131046 1.8804589370186937 0.0600455576896123 1.0 0.3366304077973894 23 Q15907,P11279,Q8NEB9,O75396,P04439,Q93050,P61026,Q03518,Q9Y487 9 +Anaphase promoting complex 0.6924780586449145 1.866953813313338 0.061908037972324 1.0 0.3442570572142164 8 Q9UJX3,Q96DE5,Q9UJX2 3 +Platelet alpha granule 0.5400716058519851 1.8650562838616072 0.0621735153497247 1.0 0.3442570572142164 16 Q9NTK5,Q9Y6I9,Q9UEU0,Q96JJ7,Q9NUQ9,P05067 6 +Haus complex 0.8834386516379729 1.8277592870860615 0.0675856859137336 1.0 0.3577791690455182 4 Q96CS2,Q9H6D7 2 +Endocytic vesicle membrane 0.4247826608954678 1.8274795486276676 0.0676276984214283 1.0 0.3577791690455182 39 Q15907,Q5T9L3,P11279,Q8NEB9,Q14108,Q93050,P61026,Q9Y487,Q8WTV0 9 +Golgi apparatus 0.4276189680628983 1.8184743558278396 0.0689916627429503 1.0 0.3597995434908513 309 Q86Y82,O75122,P98194,P49755,O75396,O43909,P50897,O95197,Q9NXE4,Q9BTU6,P80303,P24390,Q9Y282,Q9NPR9,P51572,Q9P2W9,Q9BUR5,O00400,P04439,Q96PU5,Q9Y3B3,Q8NCH0,P15291,Q5T2E6,Q5T9L3,P61019,Q8NBN3,O15127,Q15363,O95721,Q10471,Q9H4A6,Q9Y3A6,Q92896,Q7Z3D4,Q9H9E3,Q7LGA3,P10321,Q9HC07,O00461,Q5VW38,Q12907,O43752,Q96S66,O95070,Q9Y371,Q15042,Q7Z6M1,P05067,Q8IZA0,Q92845,Q9Y6B6,Q9BTV4,Q15392,Q96A57,P40616,Q8IV08,Q08AM6,Q9H8Y8,Q9NX40,Q7L5N7,Q96RL7,P04062,P53634,O14579,Q9UM00,Q92544,Q8NEY8,O75503,O43731,Q92520,Q9Y3A3,Q93050,P51790,P42345,Q99523,Q99640,Q9H7Z7,Q9Y2T2,Q10472,Q16799,Q96SU4,Q8N4V1,Q8TB61,O15118,Q96RQ1,L0R6Q1,Q14108,Q10713,Q02818,O14773,Q9NR31,P06280,P16278,P61026,Q15382,Q13190,Q9Y5U9,O15155,Q6NUQ4,O95249,Q92542,O43852,Q9BXS4,Q8TBA6,O15258,O43505,Q96L58,Q9H2C2,P35613,Q8NF37,Q99805,Q8TBQ9,Q9UEU0,P52292,O15260,Q4J6C6,O14653,Q9NX62,O00429,Q9NTJ5,Q9NRB3,Q9BRK5,P05023,Q6ZRP7,Q9H0U4 126 +Intrinsic component of presynaptic membrane 0.7499720298746025 1.805760757157524 0.0709557176979551 1.0 0.3616322657674192 5 Q92542,Q9Y639,P27824 3 +Presynaptic active zone membrane 0.7493834243735467 1.8030987716296547 0.071372704048396 1.0 0.3617023476350917 5 Q13277,Q9Y639,P27824 3 +Triglyceride rich plasma lipoprotein particle 0.9535878867676054 1.7754135690653443 0.0758296251612531 1.0 0.3677184409320611 2 Q9BUR5 1 +Intrinsic component of synaptic vesicle membrane 0.6142417475128241 1.7716514036995257 0.0764524411663609 1.0 0.3677184409320611 10 Q86Y82,O76024,P20020,O43752,Q7L0J3 5 +Platelet alpha granule lumen 0.5690509900988108 1.7504049080657575 0.0800484697132499 1.0 0.3759344362973048 12 Q9NTK5,Q9Y6I9,Q9UEU0,Q9NUQ9,P05067 5 +Autophagosome 0.4332910488023799 1.7314725837936829 0.0833675106227489 1.0 0.3815339644316622 34 Q676U5,P56962,P04844,P11279,Q969Q5,Q9UHD9,Q8NEB9,Q9Y6I9,Q96GC9,O95721,Q9Y371,Q96A57,Q9P253 13 +Er ubiquitin ligase complex 0.8557897539103174 1.71436687279515 0.0864613685588224 1.0 0.3913075051275913 4 Q9BUN8,Q9UBU6 2 +Mitotic spindle microtubule 0.6838783136858992 1.7046826710732066 0.0882536234736943 1.0 0.3958175012795192 6 Q96CS2,Q9H6D7 2 +Lumenal side of endoplasmic reticulum membrane 0.6594840177585222 1.7012970862918406 0.0888872148428665 1.0 0.396675779671897 8 P51572,P27824,P04439,Q8TCT8,Q8TCT9 5 +Azurophil granule lumen 0.4002019401936409 1.6785030228900435 0.0932489408328007 1.0 0.4140806927080311 44 O00584,Q9BTY2,P61916,P08236,Q92820,P06280,P16278,P17900,Q13217,P53634,O00560,P15586,O43681,P04066,O00754,Q9BRF8,P00387,P10619,Q05655 19 +Presynaptic active zone 0.5192592357638539 1.6668989013508644 0.0955345094028918 1.0 0.4181510892163308 15 Q99623,P27824,Q07021,Q13277,Q7L0J3,Q9Y639,P05067 7 +Integral component of cytoplasmic side of endoplasmic reticulum membrane 0.9279131007241564 1.666750268377771 0.0955640727863409 1.0 0.4181510892163308 2 Q8TCT9 1 +Chloride channel complex 0.6747709754923745 1.6603975644760365 0.0968344997874217 1.0 0.4199114895635153 6 Q9C0H2 1 +Mitochondrial proton transporting atp synthase complex coupling factor f o 0.7173847497594681 1.6574523721328018 0.0974280505024101 1.0 0.4199114895635153 5 P24539,O75964 2 +Plasma membrane raft 0.4872729108781892 1.6175424213364369 0.105761246422126 1.0 0.437178977145839 18 P09601,Q9HD47 2 +Autolysosome 0.9144173798551596 1.6094859791658251 0.1075101183850977 1.0 0.438481935339695 2 Q8NEB9 1 +Secondary lysosome 0.9144173798551596 1.6094859791658251 0.1075101183850977 1.0 0.438481935339695 2 Q8NEB9 1 +Copi coated vesicle 0.5133816633992191 1.576381314071784 0.1149379520949676 1.0 0.4535790338705108 14 O43731,P24390,P49755,Q9Y3B3,Q8N511,O14579 6 +Derlin 1 retrotranslocation complex 0.8220576337009515 1.5748503474309503 0.1152909918868188 1.0 0.4535790338705108 4 Q9BUN8,Q8TCT9 2 +Golgi associated vesicle membrane 0.4693522620362522 1.5561801209538555 0.1196652670653086 1.0 0.4582379598669469 20 O43731,O14579,P24390,Q8N511 4 +Golgi medial cisterna 0.8158761528326802 1.5491622898766615 0.1213427120834715 1.0 0.4592591254804811 4 Q9BXS4,Q96L58,O95249 3 +Proton transporting v type atpase complex 0.5553534102240337 1.5440655564374497 0.1225724519701438 1.0 0.4600313364737198 11 Q93050,Q9Y487 2 +Copi coated vesicle membrane 0.5112250591963291 1.515707654539266 0.1295932912582758 1.0 0.4823451546003044 13 O43731,O14579,P24390 3 +Zymogen granule 0.6827575023974954 1.497967724410169 0.1341416362762202 1.0 0.4846838511926144 5 P49755,Q13277,Q15363 3 +Autophagosome membrane 0.4865155447541465 1.4945556743731463 0.1350304416507548 1.0 0.4846838511926144 16 Q676U5,P04844,Q9Y6I9,Q96GC9 4 +Phosphatidylinositol 3 kinase complex 0.801955033711518 1.4911941623668934 0.1359105258804835 1.0 0.4846838511926144 4 Q8NEB9 1 +Glial cell projection 0.6805413409962708 1.4877027793382158 0.1368292943126428 1.0 0.4851220434720972 5 Q8IXJ6,P05067 2 +Microbody 0.3751683994466132 1.4609810041611302 0.1440206545674931 1.0 0.4939447016601987 51 O75381,P08670,O15254,Q9BQG2,Q9GZY8,P40855,Q96CN7,Q8NEB9,Q9UKU0,Q8N4Q0,Q9NP80,Q15067,O75192,O00429,P51648,O43808 16 +Photoreceptor connecting cilium 0.673330018687185 1.4542584616346237 0.1458746621507891 1.0 0.4939447016601987 5 Q15555,P41208 2 +Emc complex 0.6323692755447016 1.45209081603339 0.1464763552303376 1.0 0.4939447016601987 6 Q5J8M3,Q15006,Q9NPA0,Q8N4V1 4 +External side of plasma membrane 0.4593463150306933 1.4445386332610834 0.1485875206263045 1.0 0.4978782897841157 19 P11279,P02786,P42892,P49327,P08183,P07237,P51790,P04083,O96005,P15291 10 +Respiratory chain complex iv 0.6067245720948697 1.430904553387911 0.15245757188924 1.0 0.5012551804130773 8 P00403,P22695,P14406,O14548,P20674,P13073 6 +Nuclear membrane 0.3449121489329013 1.4299813231293472 0.1527223795769186 1.0 0.5012551804130773 105 Q14728,Q9BVC6,Q99720,Q86UE4,Q9BTV4,Q15154,Q9H8M7,P50402,Q9H1E5,Q9NXE4,O60783,O94901,Q9BW27,O00560,Q8N1F7,O75844,O14657,Q7Z3B4,Q8NFH5,Q8IXM6,Q9P035,P67809,P56134,Q6NUM9,Q96KC8,Q9BTX1,Q96S66,Q6ZRP7,Q14739,Q5SNT2,Q9H2V7,Q96T37 32 +Vacuolar proton transporting v type atpase v0 domain 0.8908963636408226 1.420085944751667 0.1555826616338436 1.0 0.5012551804130773 3 Q9Y487 1 +Proton transporting v type atpase v0 domain 0.8908963636408226 1.420085944751667 0.1555826616338436 1.0 0.5012551804130773 3 Q9Y487 1 +Side of membrane 0.3517143363516925 1.4196949091418454 0.1556965208650167 1.0 0.5012551804130773 68 O43464,P11279,P27824,P18031,P62942,P63218,P17900,P51572,P04439,P07237,Q9NR28,P15291,P42892,P10619,Q8TCT8,P10321,P04083,O96005,Q8TCT9 19 +Mitochondrial intermembrane space protein transporter complex 0.7823465317840146 1.409312144671934 0.158742889280623 1.0 0.5012551804130773 4 P62072,Q9Y5J9 2 +Endoplasmic reticulum tubular network membrane 0.8843428359822578 1.3943751503725712 0.1632043480388691 1.0 0.5030731965321844 3 Q9NQC3 1 +Gpi anchor transamidase complex 0.6589785831960411 1.3875231520002274 0.1652822964127946 1.0 0.504251670898651 5 Q9H490,Q92643,O43292,Q96S52 4 +Blood microparticle 0.4517872745385578 1.3554325556137008 0.1752797831230408 1.0 0.5187379671827285 18 O00560,P04062,P27105 3 +Trans golgi network membrane 0.411802036759597 1.351368104313131 0.1765775457761773 1.0 0.5187379671827285 26 Q9HC07,O15127,O43752 3 +Smooth endoplasmic reticulum membrane 0.8522053982883482 1.345098103799374 0.1785935554968798 1.0 0.5187379671827285 2 O00264 1 +Pigment granule 0.3560797270595414 1.3414704593701263 0.1797677545731208 1.0 0.5187379671827285 60 O43852,Q92820,P11279,P49755,P57088,P27824,Q13277,P35613,O75396,P07237,Q93050,P27105,P05023,P55209,O00560,O14773,Q92542 17 +Intrinsic component of peroxisomal membrane 0.7658959338949026 1.3404644169442754 0.1800944052614435 1.0 0.5187379671827285 4 O75192,O43808 2 +Golgi associated vesicle 0.3994082082024052 1.339876776353612 0.1802854094897237 1.0 0.5187379671827285 31 O43731,P24390,Q8N511,O14579,P05067 5 +Proteasome core complex beta subunit complex 0.5940656521678473 1.339430403216407 0.180430597280949 1.0 0.5187379671827285 7 P28070,P49721 2 +Dynactin complex 0.6467168092803526 1.3303458737882392 0.1834043392110556 1.0 0.5206129502288508 5 Q9UJW0 1 +Intrinsic component of nuclear inner membrane 0.5891744051477192 1.3142640882625731 0.188757347924688 1.0 0.5276991736705027 7 Q5SNT2,Q14739,O94901 3 +Gaba ergic synapse 0.5835904081718032 1.3105235995626472 0.1900187659928343 1.0 0.5276991736705027 8 Q07021,Q99623,Q9Y639,Q7L0J3 4 +Tim22 mitochondrial import inner membrane insertion complex 0.8603885413236665 1.3004017215148855 0.1934633202200038 1.0 0.5339587638072104 3 P62072,Q9Y584 2 +Plasma membrane signaling receptor complex 0.5564387786547775 1.2945862262949412 0.1954630063818898 1.0 0.5345183186019172 9 O43464,P02786,Q8N2K0,Q9NR28,O00560 5 +Ciliary basal body 0.4580428056410361 1.2926783574036027 0.196122326137806 1.0 0.5345183186019172 16 P48729,O43805,Q92845,P28070,P41208 5 +Neuromuscular junction 0.4575141689540452 1.2889038551906302 0.1974315136336828 1.0 0.5347126843090086 16 P57105,O43760 2 +Phosphatidylinositol 3 kinase complex class iii 0.8571059434332922 1.2875310178086288 0.1979092655413499 1.0 0.5347126843090086 3 Q8NEB9 1 +Zymogen granule membrane 0.7500000000000064 1.2738648119372664 0.202711330932972 1.0 0.542782280139928 4 Q13277,P49755,Q15363 3 +Hrd1p ubiquitin ligase erad l complex 0.8505396166758084 1.2617953781037723 0.2070224257344739 1.0 0.5480819901770753 3 Q9BUN8 1 +Postsynaptic specialization membrane 0.5074855011457371 1.253850461616572 0.2098963637441318 1.0 0.5505176557850474 11 Q99720,P57105,Q9Y639,P52292 4 +Gamma secretase complex 0.8291639236339705 1.247475390966293 0.2122232381224593 1.0 0.5528492775999925 2 Q92542 1 +Eukaryotic translation initiation factor 2b complex 0.6283878498444229 1.2446765505894113 0.2132506689516136 1.0 0.5528492775999925 5 Q9NR50 1 +Endoplasmic reticulum exit site 0.4420512118776009 1.228026657203665 0.2194369612296069 1.0 0.5650510792075764 17 Q96PC5,Q9Y6B6,P04439,Q5JRA6,Q9Y3A6,Q9HCU5,Q9NR31 7 +Uniplex complex 0.7388010540184752 1.2269348588901223 0.2198470754107515 1.0 0.5650510792075764 4 Q9BPX6,Q8IYU8,Q9H4I9 3 +Postsynaptic density membrane 0.5652712881533508 1.2145992439300504 0.2245189773791158 1.0 0.570519894359963 8 P57105 1 +Nuclear pore central transport channel 0.7328970073253593 1.2021999170612083 0.2292860814562392 1.0 0.5727295934370935 4 Q7Z3B4 1 +Integral component of presynaptic active zone membrane 0.7314985026174146 1.1963421225861537 0.2315630772680688 1.0 0.5727295934370935 4 Q9Y639,P27824 2 +Intrinsic component of presynaptic active zone membrane 0.7314985026174146 1.1963421225861537 0.2315630772680688 1.0 0.5727295934370935 4 Q9Y639,P27824 2 +Ciliary plasm 0.4510488570730885 1.195870753969238 0.2317469996368109 1.0 0.5727295934370935 15 Q676U5,Q92845,Q8NEB9,Q15555,P10644,Q10713 6 +Endosome lumen 0.7273422932723844 1.1789370001848245 0.2384232630166294 1.0 0.5780153160159908 4 Q9UIQ6,P05067 2 +Ubiquitin ligase complex 0.3508314710577138 1.1719153400381344 0.2412310476026882 1.0 0.5792020505278618 48 Q9BUN8,Q96K76,Q9UBS8,Q96DE5,Q9UJX2,Q9HB71,Q9UBU6,O60566,Q9UJX3,Q96P70,Q92564,Q9UBV2 12 +Cilium 0.3106705745191993 1.171256688058897 0.2414956152702567 1.0 0.5792020505278618 82 Q92845,Q15154,P35613,Q10713,P41208,Q92973,Q6PHR2,P04350,Q96RL7,P61026,Q15388,P48729,Q676U5,A6NIH7,O43924,P28070,Q15555,P10644,O95721,O14965,O43805,Q8NEB9,P05023,P04083,Q9NUQ9,P05067 26 +Mitochondrial crista 0.8258149489627922 1.165083336655804 0.2439852612039743 1.0 0.5836127447999067 3 O60313,Q9BUB7 2 +Specific granule 0.3667861012892615 1.155700983330494 0.2478034858220343 1.0 0.5904989611315282 36 P30519,Q07065,P61225,O00264,O60784,Q13277,Q08722,P27105 8 +Histone pre mrna 3 end processing complex 0.7995391705069131 1.122762546520131 0.2615383560431867 1.0 0.6057366292201843 2 O60506 1 +Golgi trans cisterna 0.8129733289430316 1.115033627100208 0.2648360119093429 1.0 0.6106886958423665 3 Q9BXS4,O15155 2 +Nuclear envelope 0.3600966459172227 1.1091988970950626 0.2673443882964228 1.0 0.6134138824731252 176 Q14728,Q9BVC6,Q96T37,Q99735,Q99720,Q92575,Q86UE4,Q9BTV4,Q15154,O15397,Q9C0E2,Q9H8M7,P50402,Q9H1E5,P41208,Q9NXE4,P80303,P57088,O60783,O94901,Q9BW27,O00560,Q8N1F7,O75844,Q9NQC3,O14657,O43592,Q7Z3B4,Q8NFH4,Q9NUQ2,Q8NFH5,Q96AG4,Q12981,Q8IXM6,Q9HB71,Q9P035,P67809,P56134,Q6NUM9,Q96KC8,Q12769,Q9BTX1,Q96S66,O15173,Q14739,O95373,Q6ZRP7,P42167,Q9H2V7,Q96P70,Q5SNT2,P05067,O15118 53 +Nuclear ubiquitin ligase complex 0.5195257951615588 1.089666728260679 0.2758599774417383 1.0 0.6167024328023535 9 Q9UJX3,Q96DE5,Q9UJX2 3 +Acrosomal vesicle 0.4215646143404843 1.0772445599421423 0.2813710228971295 1.0 0.6216215984124391 17 Q9HBM0,Q9Y487,P45880 3 +Cell body membrane 0.7870309414088226 1.0705147556568628 0.2843876707700863 1.0 0.623497523045771 2 P55011 1 +Presynapse 0.3117898912138175 1.0534649539321603 0.2921279483054428 1.0 0.6299008885336111 95 Q86Y82,Q15907,Q99623,P11279,P27824,Q07021,Q96A57,P50897,Q9BTU6,Q9GZY8,Q9UEU0,P61026,Q99808,O15400,O76024,P0DP25,O95721,O00429,O43760,Q9P253,Q92542,Q9BT78,O43752,Q13277,Q7L0J3,Q9Y639,P05067 27 +Dendrite membrane 0.7794601711652411 1.039043666722579 0.2987844283299723 1.0 0.6368655967168408 2 P20020 1 +Oligosaccharyltransferase complex 0.5283261986412806 1.0201840967624445 0.3076411584936931 1.0 0.6368655967168408 8 P04844,P46977 2 +Cd40 receptor complex 0.6877892537310704 1.0138534462255893 0.310652688071886 1.0 0.6378579024334173 4 Q9NR28 1 +Extrinsic component of organelle membrane 0.434298195531819 1.0013916684741258 0.3166374904394708 1.0 0.6425878482448085 13 Q08AM6,P62942,P04083 3 +Atpase dependent transmembrane transport complex 0.7653061224489806 0.9805691842292852 0.3268052368765031 1.0 0.6514317721738295 2 P05023 1 +Sodium potassium exchanging atpase complex 0.7653061224489806 0.9805691842292852 0.3268052368765031 1.0 0.6514317721738295 2 P05023 1 +Cation transporting atpase complex 0.7653061224489806 0.9805691842292852 0.3268052368765031 1.0 0.6514317721738295 2 P05023 1 +Nuclear outer membrane 0.4767610688151929 0.9728078597691816 0.3306488056176 1.0 0.6557479161325417 10 Q99720,Q9NXE4,P50402,Q6NUM9 4 +Inhibitory synapse 0.7623436471362748 0.9683970305289538 0.3328461219245333 1.0 0.6557479161325417 2 Q9Y639 1 +Phagocytic vesicle 0.3336517340129238 0.9668316242320956 0.3336282125173748 1.0 0.6557479161325417 42 Q86Y82,Q15907,P08670,P11279,Q8NEB9,O43752,O75396,P04439,Q93050,P61026,Q03518,Q9Y487 12 +Palmitoyltransferase complex 0.761026991441739 0.9629951902033984 0.3355499370176551 1.0 0.6557479161325417 2 O15269 1 +Endoplasmic reticulum palmitoyltransferase complex 0.761026991441739 0.9629951902033984 0.3355499370176551 1.0 0.6557479161325417 2 O15269 1 +Mitochondrial permeability transition pore complex 0.6740113031476113 0.956757313934851 0.3386897621030775 1.0 0.6598599471485578 4 P12235,P21796 2 +Endosome membrane 0.3275269919107528 0.9539576510613996 0.3401050792905848 1.0 0.6603338877135382 131 Q15907,P11279,Q14108,Q8IV08,Q14849,Q08AM6,Q99805,Q9UEU0,P61026,O60831,O15400,O95772,Q5T9L3,Q676U5,P61225,O14653,O15127,P42892,Q93050,Q9Y487,Q8TCT8,Q92542,P04083,Q9HC07,O00461,Q96L92,Q9BXS4,Q96SU4,Q8N4V1,O15118 30 +Tertiary granule membrane 0.4574322868992301 0.9457099974138864 0.3442965219165292 1.0 0.6670280349009218 11 Q08722,P61225,P27105 3 +Brush border membrane 0.5139170207926467 0.9248201452534712 0.3550594698739675 1.0 0.6806385257946083 7 Q14728,P40855 2 +Protein lipid complex 0.7541831939198509 0.8888993623984359 0.3740571681552345 1.0 0.6974781471875647 3 Q9BUR5 1 +Spindle microtubule 0.3448328642361539 0.8714739587298014 0.3834954187149642 1.0 0.7107342780729811 33 P50748,O75122,O94927,O14965,P0DP25,Q9H6D7,Q96DB5,Q96CS2,Q96TC7 9 +Signal peptidase complex 0.7488153247747573 0.868608035090577 0.385061558069854 1.0 0.7119681239484223 3 P67812 1 +Intrinsic component of synaptic membrane 0.4790970989256856 0.8644585181222502 0.387336058513746 1.0 0.7119681239484223 9 P20020,Q92542,Q9Y639,P27824 4 +Vesicle membrane 0.3652673977806979 0.8518401760904653 0.394302804250072 1.0 0.7148957524537345 257 Q14728,Q15907,P11279,P07602,Q9NZJ7,O60784,Q14108,P35613,Q9UIQ6,P10253,Q9NR31,Q8IV08,Q8NF37,Q14849,Q08AM6,P30519,P24390,Q9H0U3,Q99805,O00264,Q9UEU0,Q08722,P61026,P27105,O60831,Q03518,O14579,Q13190,O95772,Q5T9L3,Q676U5,O43924,Q07065,O43731,O76024,O15400,P56962,P0DP25,P61225,O14653,O15127,O15260,P42892,Q93050,Q96JJ7,O00429,Q8N511,O43760,Q9Y487,Q8TCT8,Q8WTV0,Q9Y2T2,Q92542,P04083,Q9HC07,O00461,Q969Q5,Q96L92,Q8NEB9,Q9BXS4,O43752,Q13277,Q7L0J3,Q96SU4,Q8N4V1,O15118 66 +Endoplasmic reticulum quality control compartment 0.5415860500635223 0.8402107966158536 0.400790205931951 1.0 0.7155627876012487 5 Q9BUN8 1 +Beta catenin destruction complex 0.6454725907605681 0.8396504584137705 0.4011043989322465 1.0 0.7155627876012487 4 Q9HB71 1 +Sarcoplasm 0.3948312046363474 0.837867420260467 0.4021051682940029 1.0 0.7155627876012487 16 O43852,Q9BVC6,P52789,P16615,P62942 5 +Postsynaptic membrane 0.3514515856313798 0.8363323545065703 0.402967956291026 1.0 0.7155627876012487 27 Q99720,Q8NCG7,P27824,P51790,Q9Y639,P57105,P52292,Q14168 8 +Cis golgi network membrane 0.7398748765228813 0.8349891610535589 0.4037238111749022 1.0 0.7155627876012487 3 P98194,Q9NPR9 2 +Coated vesicle membrane 0.3166799865984413 0.8337027073774438 0.4044485321224449 1.0 0.7155627876012487 56 P10321,P56962,P24390,O43731,P49755,O14653,Q9Y6B6,Q15363,Q14108,O75396,Q9UEU0,P04439,Q9Y3B3,Q8N511,O14579,Q9NR31,Q13190 17 +Multivesicular body 0.408325074331037 0.8261599859023483 0.4087133434593966 1.0 0.7189312723247823 13 Q9HD42,O43633,Q9NZZ3,P11279,Q9H444,O14964,P13693,Q5VYK3,Q8WUX9,P10644,Q96PU5,Q99816 12 +Endocytic vesicle 0.2875420525973469 0.8251244600026916 0.4093009342582021 1.0 0.7189312723247823 83 Q5T9L3,O00461,Q15907,P11279,Q969Q5,Q8NEB9,O43752,Q14108,Q93050,P61026,Q03518,Q9Y487,Q8WTV0 13 +Intrinsic component of vacuolar membrane 0.7264647794601403 0.8232604858184935 0.4103598789635323 1.0 0.7189312723247823 2 O15118 1 +Integral component of lysosomal membrane 0.7264647794601403 0.8232604858184935 0.4103598789635323 1.0 0.7189312723247823 2 O15118 1 +Nuclear envelope lumen 0.5331531867738053 0.8015564367929632 0.4228095855361253 1.0 0.7292387572917354 5 P05067 1 +H3 histone acetyltransferase complex 0.720539828834732 0.7997725407718158 0.4238425951907691 1.0 0.7292387572917354 2 P55201 1 +Sec61 translocon complex 0.6354115777101484 0.7988574805816799 0.4243730560828158 1.0 0.7292387572917354 4 P51571 1 +Translocon complex 0.6354115777101484 0.7988574805816799 0.4243730560828158 1.0 0.7292387572917354 4 P51571 1 +Early endosome 0.2954389630362107 0.7961561426512488 0.4259412854000386 1.0 0.7305340975216723 97 Q86Y82,Q9BUN8,O60784,P18031,Q9UIQ6,Q96A57,Q8IV08,Q08AM6,Q9UEU0,Q13510,O15400,Q5T9L3,Q9P253,Q92542,P04083,Q9HC07,Q5VW38,Q96L92,O43752,Q8N4V1,P05067 21 +Neurofilament 0.7243990780375332 0.7773814045633456 0.4369337801838244 1.0 0.7381249354245241 3 Q16352,P07196 2 +Cytoplasmic microtubule 0.3683093921425888 0.7478469774839581 0.4545524626014294 1.0 0.7477467733580593 19 Q9Y5M8,O75122,Q6NUK4,Q6NUQ4,Q9H6H4,Q9BSJ2 6 +Smooth endoplasmic reticulum 0.4202699787068064 0.7174383554792135 0.4731036602063927 1.0 0.7577182670107411 11 P05067,O00264,P27824 3 +Cortical endoplasmic reticulum 0.7025322563952825 0.6974757142909556 0.4855051326550925 1.0 0.76672201406975 3 Q9H2C2 1 +Recycling endosome 0.3133997103230866 0.6949736553843167 0.4870718116085482 1.0 0.7678443146096094 39 Q86Y82,Q15907,P61225,O15127,Q9UEU0,P04439,P61026,Q96A57,O14773,P05067,O15400 11 +Trans golgi network 0.3004386888964567 0.6912405470466129 0.4894143868151546 1.0 0.7700357333927005 62 O75122,Q9NXE4,P98194,Q9BTU6,Q5T9L3,Q4J6C6,Q9HC07,Q9NPR9,Q9NX62,O15127,O43752,P61026,P04062,Q96A57,Q9H4A6,Q7Z6M1,Q9H9E3,P05067 18 +Paranode region of axon 0.6902567478604151 0.6824352503877458 0.4949637724472937 1.0 0.7721434850177782 2 Q8IXJ6 1 +Myelin sheath 0.3981282180922488 0.664296460289271 0.5065005861179175 1.0 0.7805463063858328 12 P0DP25,Q8IXJ6 2 +Escrt complex 0.4424282415044638 0.662315138571531 0.507769276813339 1.0 0.7805463063858328 9 Q9BRG1,O14964,O43633,Q9H444,Q92783,Q8WUX9,Q9H9H4,Q99816 8 +Messenger ribonucleoprotein complex 0.49405214170402 0.6258854009474855 0.5313901108641859 1.0 0.8038059518468376 5 P67809,Q99729,Q06787 3 +Nuclear pore outer ring 0.4494885835350403 0.6093648497126476 0.5422826312533702 1.0 0.8079853381464436 8 Q12769,P57740,Q8NFH4,Q9BW27 4 +Cytoplasmic side of endoplasmic reticulum membrane 0.4489609634943615 0.6066827436951521 0.5440614762992775 1.0 0.8079853381464436 8 Q8TCT9,Q8TCT8 2 +Tor complex 0.6658986175115216 0.5920274624376957 0.5538321987500334 1.0 0.81042003634385 2 P42345 1 +Torc1 complex 0.6658986175115216 0.5920274624376957 0.5538321987500334 1.0 0.81042003634385 2 P42345 1 +Endolysosome 0.3972628936899863 0.5784799458805203 0.5629401329242598 1.0 0.8184072921119304 11 P53680,Q676U5,Q05655,Q99538 4 +Endosome 0.33724269502147 0.57657562106669 0.5642261718492558 1.0 0.8189496377812014 212 Q86Y82,Q9BUN8,Q15907,P11279,P07602,Q9NZJ7,Q99538,O60784,Q14108,P35613,P18031,Q9UIQ6,Q96A57,O14773,Q8IV08,Q14849,Q08AM6,Q9BTU6,Q9NX40,Q99805,Q9UEU0,P04439,P61026,Q13510,O60831,O15400,O95772,Q5T9L3,Q676U5,P61225,O14653,O15127,P42892,Q93050,Q9Y487,Q8TCT8,Q92542,Q9P253,P04083,Q9HC07,O00461,Q5VW38,Q969Q5,Q96L92,Q8NEB9,Q9BXS4,Q9BRK5,O43752,Q05655,Q96SU4,Q8N4V1,P05067,O15118 53 +Prefoldin complex 0.5737812911725955 0.557767292759017 0.5770032996919809 1.0 0.8281151357179309 4 Q9UHV9,P61758,O15212 3 +Receptor complex 0.3587061715026345 0.5495377196845572 0.5826364862642577 1.0 0.8283563770493865 15 O00560,P05067 2 +Er membrane insertion complex 0.6504279131007156 0.5368397884648658 0.5913782850936142 1.0 0.8314519149356927 2 P46379 1 +Postsynaptic specialization intracellular component 0.5671936758893279 0.533193048198471 0.5938999532737892 1.0 0.8323879032602951 4 O60716,P35222,Q9UQB8 3 +Postsynaptic density intracellular component 0.5671936758893279 0.533193048198471 0.5938999532737892 1.0 0.8323879032602951 4 O60716,P35222,Q9UQB8 3 +Photoreceptor inner segment 0.4432988455391676 0.519595436052498 0.603345579761593 1.0 0.8397006324724868 6 P05023,P35613 2 +Multivesicular body membrane 0.4419907712590656 0.5135473207826958 0.6075685183483022 1.0 0.8423322425941685 6 O43633,O14964,Q9NZZ3,Q9H444,Q8WUX9 5 +Mitochondrial alpha ketoglutarate dehydrogenase complex 0.6329822251481253 0.477009777622696 0.6333551591411348 1.0 0.862093441198176 2 P11182 1 +Nuclear pore 0.2875591226019039 0.4713731080554376 0.6373743164170564 1.0 0.8623524767583549 49 O43633,O43592,Q7Z3B4,Q8NFH4,Q12769,Q8NFH5,Q9BTX1,O95373,P57740,Q9C0E2,Q9BW27,Q8N1F7,Q9NRG9,P41208 14 +Rough endoplasmic reticulum membrane 0.3375278288223203 0.4642879436838165 0.6424414606226656 1.0 0.8623524767583549 17 Q9Y5M8,Q96A33,Q9UGP8,P51571,Q15041 5 +Neuron projection membrane 0.4220652590035939 0.463790263320874 0.6427980199078722 1.0 0.8623524767583549 7 Q9HBM0,P20020 2 +Sarcoplasmic reticulum membrane 0.4016435910202199 0.4450044532536356 0.6563165358996088 1.0 0.8747636444308308 9 P16615,P62942 2 +Transcription factor tfiih holo complex 0.6214614878209364 0.4390450702530036 0.6606288792797637 1.0 0.8747975767818393 2 P18074 1 +Mitochondrial small ribosomal subunit 0.338119652396852 0.4382318323757689 0.6612182352932967 1.0 0.8747975767818393 16 O60783 1 +Dopaminergic synapse 0.6201448321264005 0.4347897171570703 0.6637150694475182 1.0 0.8761550417307702 2 O75955 1 +Amphisome 0.4418451400329508 0.4062432989879647 0.6845638425202292 1.0 0.8890920231707614 5 Q8WUX9,O43633,Q9NZZ3,Q9H444 4 +Amphisome membrane 0.4418451400329508 0.4062432989879647 0.6845638425202292 1.0 0.8890920231707614 5 Q8WUX9,O43633,Q9NZZ3,Q9H444 4 +Ragulator complex 0.6099407504937422 0.4024185279307606 0.6873760366417967 1.0 0.8897204976445766 2 Q9Y2Q5 1 +Apical part of cell 0.2801449646576385 0.3945642051824884 0.6931645346657485 1.0 0.8911223567181944 52 P20020,P36543,O75955,Q86UE4,Q99538,Q15154,O00165,P41208,P08183,Q99808,Q99797,P54709,P08195,P51790,P36551,Q13277,P05023,P11166,P04083,P05067,P55011 21 +Neuronal ribonucleoprotein granule 0.6119099531398482 0.3942095771480809 0.6934263154841691 1.0 0.8911223567181944 3 Q99729 1 +Cop9 signalosome 0.374242169550768 0.3820256344524348 0.7024423505688966 1.0 0.900129697800429 10 Q9BT78,Q9UNS2,P62993,Q99627,Q92905 5 +Cullin ring ubiquitin ligase complex 0.2982755769551387 0.3751340689266658 0.7075607607346512 1.0 0.903198584620846 27 Q96K76,Q96DE5,Q9UJX2,Q9UJX3,Q9HB71 5 +Organellar ribosome 0.2765314079756318 0.3548526265999602 0.7227000002494939 1.0 0.9113622647061028 44 O60783,Q7Z7H8,Q7Z7F7,Q567V2 4 +Main axon 0.3691637423053742 0.3547407109644922 0.7227838489207541 1.0 0.9113622647061028 10 Q8IXJ6,P05067,Q14168 3 +Synaptic membrane 0.2750588053107688 0.326278976324685 0.7442132930965308 1.0 0.9258455498684908 40 Q9BTU6,P20020,Q99720,Q8NCG7,Q06787,P27824,Q13277,P51790,Q9Y639,Q9UQB8,O14936,P57105,Q8NBU5,Q92542,P52292,Q14168 16 +Apical plasma membrane 0.2754829921819263 0.3114674433952656 0.7554452892323309 1.0 0.927230728141826 39 P20020,P36543,O75955,Q86UE4,Q9NP72,O00165,P08183,Q99808,Q99797,Q9P289,P54709,P08195,P51790,P36551,P53985,Q13277,P05023,P11166,P04083,P55011 20 +Basolateral plasma membrane 0.2859906389662968 0.3110592622422338 0.7557555699045384 1.0 0.927230728141826 32 P02786,P20020,P54709,P04083,P05023,P35613,P08195,P11166,O14936,P57105,P15291,Q99808,P55011,Q14168 14 +Tertiary granule 0.2730008471313845 0.3058193516258383 0.7597421934736865 1.0 0.9284587841224752 40 Q92820,P11279,P61225,P09960,Q08722,Q93050,P10253,P27105,Q13510 9 +Mhc protein complex 0.5707740646313952 0.278137745258272 0.7809066218963334 1.0 0.9414962901088858 3 P04439 1 +Mhc class i protein complex 0.5707740646313952 0.278137745258272 0.7809066218963334 1.0 0.9414962901088858 3 P04439 1 +Immunological synapse 0.3189516772563906 0.2528821473660074 0.8003592855278256 1.0 0.9546987557141198 13 Q96L92,P20020,Q9UJZ1,P10644,Q9Y639,O15400 6 +Myelin sheath abaxonal region 0.4822134387351775 0.2492599230791649 0.8031597298295732 1.0 0.9546987557141198 4 P05556,Q96A65,P09543 3 +Carboxy terminal domain protein kinase complex 0.5594336516298883 0.2492206100540816 0.803190137782483 1.0 0.9546987557141198 3 P18074,Q96T76 2 +Juxtaparanode region of axon 0.4811103386853135 0.2460779667885977 0.8056218786959872 1.0 0.9546987557141198 4 Q8IXJ6,Q14168 2 +9plus0 non motile cilium 0.3481273763061903 0.2456004058478191 0.8059915750345572 1.0 0.9546987557141198 10 Q15555,P35613,P41208 3 +Secretory vesicle 0.3271309642890513 0.245095769385685 0.8063822785846106 1.0 0.9546987557141198 259 Q86Y82,Q15907,P11279,P49755,O00584,Q9NZJ7,P07602,O60784,Q8NBX0,Q9Y6I9,P35613,P46976,P10253,Q96A57,P50897,Q9BTY2,Q8NF37,P08236,P61916,Q92820,P30519,P06280,Q9H0U3,P16278,Q9GZY8,P17900,Q9NTK5,P45880,O00264,Q5T9A4,O00231,Q9UEU0,Q08722,P61026,P27105,Q13510,O00560,P15291,P15586,O15400,O15260,Q07065,O76024,Q92520,P04066,P0DP25,O00754,P61225,Q9BRF8,P09960,Q15363,P00387,P42892,Q93050,P10619,Q96JJ7,O00429,O43760,Q9Y487,Q92542,Q9BT78,Q969Q5,Q9HBM0,O43752,Q13277,Q7L0J3,Q05655,P06865,Q9NUQ9,P05067 70 +Nucleotide activated protein kinase complex 0.4806835285480808 0.2448509054285803 0.8065718764736849 1.0 0.9546987557141198 4 P54646,P10644 2 +Nucleoid 0.2772135946665968 0.2446109303703434 0.8067576999234145 1.0 0.9546987557141198 33 P05141,Q96RR1,P45880,Q96AG4,P21796,P51530,Q9NUL7 7 +Cell surface 0.2558530125623135 0.2283457063413939 0.8193774944649697 1.0 0.9660043810605992 71 O15258,Q99623,P11279,Q07021,P04439,P07237,Q08722,P15291,P06576,P42892,P51790,Q96JJ7,Q8WTV0,P10321,Q12907,Q9Y639,P04083,O96005,Q8TCT9,P05067 20 +Recycling endosome membrane 0.2823203558764188 0.2194107374059423 0.8263301065632489 1.0 0.9697363056390614 25 Q86Y82,Q15907,P10321,P02786,O14828,P61225,Q96PE3,O15127,P61106,Q9UEU0,P04439,P61026,O15126 13 +Kinetochore microtubule 0.3518701449944597 0.2026440887784958 0.839413227007848 1.0 0.9743351354425864 9 P50748 1 +Wash complex 0.5396773131379595 0.2023483079728698 0.8396444366746034 1.0 0.9743351354425864 3 P52907,Q9Y3C0 2 +Laminin complex 0.5325872284397648 0.1975094055812257 0.8434289218223627 1.0 0.9774622000964592 2 P07942 1 +Rna polymerase ii transcription repressor complex 0.5292955892034251 0.1905559562905995 0.8488734995727281 1.0 0.9819807670590842 2 P35222 1 +Cuticular plate 0.5283080974325234 0.1884997888319914 0.8504848810368029 1.0 0.9819807670590842 2 Q9Y5X1 1 +Scf ubiquitin ligase complex 0.3635561602416902 0.1855450098937572 0.8528015803110665 1.0 0.9819807670590842 6 Q9HB71 1 +Gemini of coiled bodies 0.3749588138385585 0.1692319306869384 0.8656142149443629 1.0 0.989728839075642 5 P57678,Q9UHI6,Q16637,O75312 4 +Smn complex 0.3749588138385553 0.1692319306869288 0.8656142149443704 1.0 0.989728839075642 5 P57678,Q9Y3F4,Q16637,Q9UHI6 4 +Intrinsic component of postsynaptic membrane 0.3569535668910822 0.162080077706279 0.8712427944374768 1.0 0.9930175179293732 6 Q9Y639,P27824 2 +Escrt i complex 0.5062541145490473 0.1461906794105598 0.8837708632650394 1.0 0.9984162019505546 2 Q9H9H4 1 +Escrt iii complex 0.4416996047430872 0.143013007610412 0.8862799082061268 1.0 0.9997320611649676 4 Q8WUX9,O43633,Q9H444 3 +Cytolytic granule 0.5105806783842644 0.1418927981031875 0.887164683040484 1.0 0.9997320611649676 3 P11279 1 +Smc5 smc6 complex 0.5090549884754619 0.1390139824115534 0.8894390999654296 1.0 1.0 3 Q96SB8,Q96MF7 2 +Cytoplasmic side of membrane 0.2532068772720935 0.127538160726032 0.8985144718824452 1.0 1.0 42 O43464,P17900,Q8TCT9,P18031,Q9NR28,Q8TCT8,P62942,P63218 8 +Protein phosphatase type 2a complex 0.3571663920922643 0.1180739876431755 0.90600903410566 1.0 1.0 5 P63151,Q15257,P30153,P30154 4 +Proteasome core complex 0.2894208933259686 0.1148213927381956 0.9085866922489174 1.0 1.0 15 P25787,Q92530,P49721,P28070,P28072 5 +Crd mediated mrna stability complex 0.3428307254874775 0.1146756190641544 0.908702239584492 1.0 1.0 6 O60506,Q08211 2 +9plus2 motile cilium 0.2804322644455709 0.1143338962972575 0.908973113310882 1.0 1.0 18 P05023,Q96RL7,P10644,Q15388,P41208 5 +Sperm annulus 0.4779460171165263 0.101959565333278 0.9187887699551432 1.0 1.0 2 Q15019 1 +Copii vesicle coat 0.3256606204977224 0.0915669279835502 0.9270421286708552 1.0 1.0 9 Q9NR31,Q9Y3B3 2 +Non motile cilium 0.2852043537192995 0.0801685257942117 0.9361032223443791 1.0 1.0 14 Q15555,P35613,Q92845,P41208 4 +Wnt signalosome 0.4591836734693901 0.0786521554791105 0.9373093019204676 1.0 1.0 2 P35222 1 +Intraciliary transport particle b 0.4344963791968424 0.0546867927478817 0.9563879914773612 1.0 1.0 2 A0AVF1 1 +Intraciliary transport particle 0.4344963791968424 0.0546867927478817 0.9563879914773612 1.0 1.0 2 A0AVF1 1 +Anchored component of membrane 0.3190507580751524 0.0441655490697148 0.9647724431036666 1.0 1.0 6 P51149,Q9ULX3,P36551,P20339,P61020 5 +Caspase complex 0.3188985578041832 0.0437539957345052 0.9651004980235128 1.0 1.0 6 Q9H490,Q92643,O43292,Q96S52 4 +Ap 3 adaptor complex 0.4441872445349689 0.0435982832609655 0.96522462015746 1.0 1.0 3 Q9P253 1 +Cul4a ring e3 ubiquitin ligase complex 0.4173798551678759 0.042069704250903 0.966443131285874 1.0 1.0 2 Q92990 1 +Early endosome membrane 0.2457155774105593 0.0374452822268919 0.9701299679727138 1.0 1.0 48 Q86Y82,Q08AM6,Q5T9L3,Q9HC07,Q96L92,Q9UEU0,P04439,P04083,Q8N4V1,Q8IV08,O15400 11 +Postsynaptic endocytic zone 0.4098090849242946 0.0374164910544295 0.9701529239176164 1.0 1.0 2 P09496 1 +Neurofibrillary tangle 0.4084924292297586 0.0366611584423737 0.9707551788818982 1.0 1.0 2 P07197 1 +Presynaptic endocytic zone 0.408626934474801 0.0121389877754559 0.9903147269330476 1.0 1.0 3 P09497,P09496 2 +Anchored component of plasma membrane 0.3186306780776854 0.0118026838414697 0.9905830394230476 1.0 1.0 2 P36551 1 +Mitochondrial large ribosomal subunit 0.2499783777872496 0.0086094948091719 0.9931307018781772 1.0 1.0 28 Q7Z7H8,Q7Z7F7,Q567V2 3 +Mhc class i peptide loading complex 0.3622313117662282 0.0043787533669606 0.9965062714574318 1.0 1.0 4 Q03518 1 +Risc loading complex 0.3905763428504353 0.000901025429465 0.9992810858182136 1.0 1.0 3 Q08211 1 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ac26d097bb5a617de1859dd54cdc67eaa4ad48c3 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atg1 ulk1 kinase complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Deuterosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Procentriole replication complex", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG8", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC1", "ARMC10", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATG13", "ATG16L1", "ATG7", "ATG9A", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL2L13", "BCLAF1", "BCS1L", "BDH2", "BET1", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOP1", "BRD2", "BRI3BP", "BRIX1", "BRPF1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C10orf76", "C12orf43", "C12orf73", "C14orf2", "C17orf75", "C19orf70", "C1QBP", "C1orf35", "C20orf24", "C2orf49", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CAST", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC86", "CCDC88A", "CCDC93", "CCDC94", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPK", "CENPU", "CENPV", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHMP1A", "CHMP2A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLTA", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG4", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPE", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CWC15", "CWF19L1", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELOB", "ELP1", "ELP2", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERCC2", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM162A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FOXRED2", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GFM1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GORASP2", "GOSR1", "GOSR2", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSR", "GSTK1", "GSTM3", "GSTZ1", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HECTD3", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD2A", "HIKESHI", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK3", "HP1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ISCU", "ISOC1", "IST1", "ITCH", "ITGB1", "ITSN2", "IVD", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFAP3", "KIFBP", "KIFC1", "KLC1", "KLC2", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM7", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "M6PR", "MACF1", "MAD1L1", "MAGED2", "MAGT1", "MAK16", "MAN1A2", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAPK1", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCH5", "MARCKS", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBIP", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED24", "MED25", "MEPCE", "MESD", "METTL1", "METTL14", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MIB1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL3", "MRPL37", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS14", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MXRA7", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NF1", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NKRF", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRM", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NTHL1", "NUB1", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OSTM1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAWR", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDXDC1", "PDXK", "PECR", "PEF1", "PELP1", "PES1", "PEX11A", "PEX14", "PEX16", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN4", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN23", "PTRH2", "PUM1", "PUM3", "PURA", "PWP2", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTF1", "RTN1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC15A4", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC37A4", "SLC3A2", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6L", "TAP1", "TARDBP", "TARS2", "TBC1D10A", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM33", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMLHE", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN6", "TSR1", "TTC1", "TTC19", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNG", "TXNDC12", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3C", "UBE4A", "UBE4B", "UBLCP1", "UBQLN2", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "ULK3", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WASHC3", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR61", "WDR70", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WLS", "WRAP53", "WTAP", "XAB2", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H13", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC8", "ZCRB1", "ZFR", "ZMPSTE24", "ZMYM2", "ZNF207", "ZNF326", "ZNF593", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["AAAS", "ABCB1", "ABCB7", "ABCD3", "ABHD10", "ABHD12", "ACAT2", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL6", "ADPGK", "AGK", "AGPAT5", "AGPS", "AHSA1", "AK3", "ALDH3A2", "ALG1", "ALG12", "ANAPC16", "ANAPC7", "ANKLE2", "ANXA1", "ANXA7", "AP2S1", "AP3M1", "APOL2", "APOO", "APP", "ARL1", "ARL6IP1", "ARMC1", "ARMC10", "ARMCX3", "ARV1", "ASAH1", "ASNA1", "ATAD1", "ATAD3A", "ATAD3B", "ATG16L1", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1E1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BAG6", "BAIAP2", "BCAP31", "BCL2L13", "BET1", "BNIP1", "BRI3BP", "BRPF1", "BSG", "BUB1B", "C10orf76", "C12orf73", "C14orf2", "C19orf70", "C1QBP", "CACYBP", "CALM3", "CALU", "CANX", "CAPZA1", "CASK", "CCDC134", "CCDC47", "CD47", "CDC23", "CDKAL1", "CDS2", "CERS2", "CETN2", "CHCHD3", "CHMP1A", "CHMP2A", "CHMP4B", "CHMP5", "CHMP7", "CHST12", "CHST14", "CISD1", "CKAP4", "CLASP2", "CLCC1", "CLCN3", "CLN5", "CLPP", "CLPTM1", "CLTA", "CLTB", "CNP", "COA3", "COA7", "COG4", "COPE", "COPS3", "COPS4", "COPS5", "COPS8", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX7A2", "COX7A2L", "CPOX", "CPPED1", "CPT1A", "CPT2", "CRTAP", "CSNK1A1", "CTNNB1", "CTNND1", "CTSA", "CTSC", "CYB5B", "CYB5R3", "CYP51A1", "DAGLB", "DBT", "DCTN4", "DCTPP1", "DCUN1D4", "DDRGK1", "DDX20", "DDX28", "DERL1", "DHCR24", "DHDDS", "DHFR", "DHRS1", "DHRS7", "DHX9", "DIABLO", "DNA2", "DNAJC1", "DNAJC11", "DNAJC3", "DNM1L", "DOLPP1", "DPM1", "EBP", "ECE1", "EIF2B3", "EMC2", "EMC4", "EMC7", "EMD", "EPDR1", "EPHX1", "ERAP1", "ERCC2", "ERGIC2", "ERGIC3", "ERLIN2", "ERMP1", "ERO1A", "ETFDH", "EXOC4", "EXTL3", "FADS2", "FAM162A", "FAM3C", "FAM49B", "FAM8A1", "FASN", "FDFT1", "FKBP14", "FKBP1A", "FKBP2", "FKBP7", "FKBP9", "FLOT1", "FMR1", "FOXRED1", "FUCA1", "FUCA2", "FUNDC2", "GAA", "GALNT1", "GALNT2", "GBA", "GDAP1", "GEMIN4", "GGCX", "GGH", "GHITM", "GLA", "GLB1", "GLG1", "GLMN", "GM2A", "GNG5", "GNS", "GOLGA5", "GOLIM4", "GOLPH3", "GORASP2", "GOSR1", "GOSR2", "GPAA1", "GPD2", "GPR107", "GPR108", "GPX8", "GRB2", "GRPEL1", "GSTZ1", "GUSB", "GYG1", "HACD3", "HADH", "HADHA", "HAUS1", "HAUS4", "HAUS5", "HAX1", "HCCS", "HEXA", "HGS", "HIGD2A", "HK2", "HLA-A", "HLA-C", "HM13", "HMOX1", "HMOX2", "HNRNPAB", "HNRNPR", "HS2ST1", "HSD17B11", "HSD17B12", "HSDL1", "HSPA13", "HTRA2", "ICMT", "IER3IP1", "IKBIP", "ILVBL", "IMMT", "IMPAD1", "INA", "INPP4A", "IPO7", "IPO8", "IPO9", "ISOC1", "ITGB1", "JAGN1", "KDELR1", "KDELR3", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIFAP3", "KNTC1", "KPNA2", "LAMB1", "LAMP1", "LAMTOR2", "LARS", "LBR", "LDAH", "LETM1", "LGMN", "LMAN2", "LMF2", "LNPEP", "LPCAT1", "LPCAT2", "LRRC59", "LRRC8C", "LTA4H", "LYSMD3", "MAGT1", "MAN2B1", "MAPRE2", "MAVS", "MBOAT7", "MCAT", "MCL1", "METTL7B", "MFF", "MFN1", "MFN2", "MFSD10", "MGST2", "MIA2", "MIA3", "MICU1", "MICU2", "MINDY3", "MIPEP", "MMGT1", "MMS19", "MOB4", "MOSPD2", "MPP2", "MPV17L2", "MRPL10", "MRPL46", "MRPL55", "MRPS14", "MRPS33", "MRPS9", "MSMO1", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTOR", "MTX1", "MTX2", "MXRA7", "NAGLU", "NAP1L1", "NCLN", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFS2", "NEDD4L", "NEFL", "NEFM", "NNT", "NOB1", "NPC1", "NPC2", "NPTN", "NRM", "NSMCE2", "NUCB1", "NUCB2", "NUDT12", "NUP107", "NUP160", "NUP35", "NUP37", "NUP54", "NUP85", "NUP93", "OCIAD1", "OLA1", "OMA1", "OPA1", "OPA3", "OSBPL9", "OSTM1", "OXA1L", "P3H4", "P4HA1", "P4HA2", "P4HB", "PCM1", "PCYOX1", "PDCD6IP", "PDCL3", "PDE6D", "PDPR", "PDSS1", "PEX11A", "PEX14", "PEX16", "PEX19", "PEX5", "PFDN2", "PFDN6", "PGRMC1", "PGRMC2", "PHB2", "PI4K2A", "PIGG", "PIGK", "PIGS", "PIGU", "PIK3C3", "PISD", "PITRM1", "PKMYT1", "PLA2G15", "PLBD2", "PLD3", "PMPCA", "PNPLA8", "PON2", "POR", "PPHLN1", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPT1", "PPT2", "PRAF2", "PRCP", "PREB", "PREPL", "PRKAA2", "PRKAR1A", "PRKCD", "PSAP", "PSMA2", "PSMB2", "PSMB4", "PSMB6", "PSMD11", "PSMF1", "PTGES2", "PTPA", "PTPMT1", "PTPN1", "QSOX2", "RAB10", "RAB11B", "RAB14", "RAB18", "RAB1B", "RAB24", "RAB2A", "RAB3GAP1", "RAB5A", "RAB5B", "RAB7A", "RABEPK", "RANGRF", "RAP2B", "RBM15", "RCN2", "RDH13", "RDH14", "REEP3", "REEP4", "REEP5", "RER1", "RETSAT", "RHEB", "RINT1", "RMDN1", "RMDN3", "RNASET2", "RNF14", "RPN2", "RRM2", "RTN1", "RTN3", "RTN4", "SACM1L", "SAMM50", "SAR1A", "SAR1B", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCFD1", "SCO1", "SDCBP", "SDF4", "SDHB", "SEC11A", "SEC22B", "SEC62", "SEC63", "SEL1L", "SEPT2", "SET", "SFXN4", "SGPL1", "SH3GLB1", "SIGMAR1", "SIRT2", "SLC12A2", "SLC16A1", "SLC25A10", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC29A1", "SLC2A1", "SLC33A1", "SLC35A4", "SLC35B2", "SLC37A4", "SLC3A2", "SMC6", "SMDT1", "SMN1*", "SMPD4", "SNAP29", "SNX27", "SNX9", "SOAT1", "SORT1", "SPCS2", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SRP68", "SRP9", "SRPRB", "SSNA1", "SSR1", "SSR4", "STAM", "STARD3", "STARD3NL", "STARD7", "STIM2", "STK26", "STOM", "STOML2", "STRAP", "STT3A", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "SUN1", "SURF4", "SV2A", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAP1", "TARS2", "TBL2", "TECR", "TEX264", "TFRC", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TM9SF2", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMEM109", "TMEM11", "TMEM126A", 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25 39 3.458965065507356 0.0005422552318443 16.271844660194176 41.71116504854369 1.2957221273899948 0.3267733012969381 7.788084220174416 5.097264791179653 1.6571109350293016 0.3632481416270505 0.0348303937648166 0.4354616437047781 0.3139585525038253 0.0244565395292078 0.0121060150206101 +Nucleotide transmembrane transporter activity 10 12 3.384726938978908 0.000712490945177 5.606796116504855 12.029126213592232 1.4217258291760082 0.2036087501116975 3.0234925518113496 1.8899648667798992 1.291115513359647 0.2666064512499804 2.858345057399388e-08 0.0044823878286489 0.0010099703116007 0.0001186481206876 7.331823684166441e-10 +Proton transmembrane transporter activity 20 38 3.2769551584278727 0.0010493303295682 12.769417475728156 35.478155339805824 1.2352045534927034 0.2879171268332734 5.319202861157036 2.7149368379617917 1.7021108079122016 0.3308025072902738 3.440600220488492e-06 0.0053226708337122 7.389910731518841e-05 1.0679246842113709e-05 2.0959915925833104e-06 +Active transmembrane transporter activity 39 67 3.2652109172350725 0.0010938259407775 26.354368932038835 73.12621359223301 1.313035419122872 0.3239574057550545 11.878456281473593 8.663537710607383 1.88741562841277 0.3851687956916088 0.0042202036399411 0.6257595800989444 0.1297043702732698 0.0251693867480244 0.0003270676653892 +Tetrapyrrole binding 9 16 3.2625491829411217 0.0011041501152948 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 0.000886726110454 0.0021781449325651 0.0017566671607845 0.0096445533674611 0.0002346698535802 +Carbohydrate derivative transmembrane transporter activity 9 12 3.241825701643869 0.0011876663570344 4.672330097087379 10.12135922330097 1.0096229459917263 0.2944050311743799 2.686158589641687 1.471354338494036 1.2935479322863277 0.3146313980204608 3.7192846846039344e-05 1.0 0.2223047329091382 0.0242110622206542 1.7807118693158284e-07 +Protein transporter activity 10 15 3.2347187940311484 0.0012176258887777 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 2.808566650769759e-05 0.0002227197090729 3.3768958612978955e-06 1.489157318519952e-06 1.4416472873703857e-06 +Snap receptor activity 13 19 3.226979871538149 0.0012510426042744 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 0.0002341148965504 0.151306852499084 0.2802926639431586 0.0484311287755044 3.336789657314716e-07 +Secondary active transmembrane transporter activity 18 21 3.128512229597274 0.0017569369939349 9.080097087378642 21.490291262135923 1.2627683473613005 0.2947710034053126 5.466215032972134 3.0675886156990426 1.4241587428281404 0.3340388164945335 0.2401836399163682 1.0 0.2072288126229632 0.0621642703962852 0.0639136560040006 +Sterol binding 9 17 3.003182912590212 0.0026717180069071 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 0.0003403293378086 0.0128452267182733 0.004885623522166 0.0016346598494465 0.0002681869997004 +Macromolecule transmembrane transporter activity 8 14 2.9776227352236826 0.0029049330973744 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 0.0007335705855627 0.0001122733832082 1.0236679094826864e-06 9.22092773458021e-05 2.7537597807274675e-05 +Protein transmembrane transporter activity 8 12 2.960948046748091 0.0030669366919886 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 0.0003215953133908 6.765318543664244e-05 4.180168207037102e-07 3.906142953800441e-05 7.850220860580527e-06 +Monooxygenase activity 6 8 2.8961065479099077 0.0037782409492488 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 4.859097108404572e-05 0.0002813337316999 0.0001188562693173 3.671693537728937e-05 0.000234374088003 +Cholesterol binding 8 14 2.8604606182152845 0.0042302608959259 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 0.0007765366578398 0.0090330503435184 0.0028960612595367 0.0056128198685199 0.0004732841187851 +Purine nucleotide transmembrane transporter activity 7 9 2.842106075761059 0.0044816577370108 4.334951456310679 9.441747572815531 0.9917737457277228 0.2833655940290197 2.4104227054611673 1.6217588601139772 1.262135146193827 0.3001583617421954 1.6423347005604462e-05 1.0 0.1432798584585485 0.0062267265321947 2.701670996055716e-07 +Alcohol binding 9 18 2.776995946800286 0.0054863863138672 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 0.0110171777184122 0.0239365913088697 0.0121763996061805 0.0324447271269302 0.0100459976774882 +Passive transmembrane transporter activity 19 32 2.719629756798452 0.0065355047685546 10.728155339805824 34.00242718446602 0.8598494327527568 0.3171523987434088 5.464704354730218 4.259483301090722 1.5882390061019254 0.3339692919660049 0.0287515036768398 0.0021318990396178 0.0007816352528268 0.020682535454445 0.0226962394481026 +Molecular carrier activity 19 35 2.697851670097565 0.0069788528937826 8.985436893203884 32.922330097087375 0.4263347027610819 0.5995318029338973 4.267144921372851 3.1428430650945036 0.9199841946557948 0.3455794463799358 0.0054573297990931 0.0305319028295214 0.0173242512102645 0.0120464435451714 7.783061920382117e-05 +Metalloendopeptidase activity 4 15 2.615115104436153 0.0089197390218338 5.449029126213592 14.364077669902912 1.4597326207035937 0.2246869419023046 2.4848715129851016 0.6671711573432166 0.9390012824303952 0.2775881383017788 0.0075007883938738 1.0 0.2732850813359189 0.0449350347407693 0.0205229364106292 +Hydrolase activity hydrolyzing o glycosyl compounds 11 21 2.5994877104776397 0.0093363021448635 8.830097087378642 20.84223300970874 0.5983257656540719 0.2104301479001341 3.2223833352824554 2.4557961681485057 1.9540573665272416 0.2728112677124137 0.0003919231836589 1.0 1.0 0.1099245732268714 0.0004353880265266 +Sulfur compound transmembrane transporter activity 4 6 2.5617757333722286 0.0104138540097877 2.9635922330097086 6.752427184466019 1.4746434057995097 0.1672652154050841 1.7026919602194592 1.5538455059459366 1.0954441166028872 0.2266277553273111 0.0042469242101728 1.0 0.0026246094830452 0.0322769586697076 0.012033886898071 +Hexosyltransferase activity 15 34 2.5555839359857555 0.0106009790303709 9.633495145631068 33.87864077669903 0.7349501031127185 0.3949358882560483 4.261380470236419 4.330948695045228 1.2646745007039175 0.3422146027467064 0.0110823588665356 1.0 1.0 0.020682535454445 0.0226962394481026 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 9 34 2.544576855572911 0.0109410231703732 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.0026427319999788 0.0099984448704361 0.0122106671185157 0.0072747996350223 0.0053243369879504 +Vitamin transmembrane transporter activity 3 6 2.5339575855607768 0.0112782381982043 2.7766990291262137 6.252427184466019 1.4438342367310928 0.182339474606115 1.52603324115363 1.3650879028699858 1.0282691527982806 0.2346378729908682 0.0049881070407295 0.0875404472016038 0.1677870330809631 0.0102137155300364 0.0119688845689888 +Molecular transducer activity 9 30 2.533398248223348 0.0112962531052032 10.91747572815534 33.40533980582524 1.343848990749489 0.2329582295822712 4.7124072380860955 5.830391636254363 1.6098335072319665 0.2956883791113679 0.515760348248732 0.7160221244847005 0.9198528304142816 0.2883362816761057 0.8124884234214369 +Ceramide binding 4 5 2.5219448145845176 0.0116708015911612 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 7.583382097353882e-05 0.0607401038440192 0.0066572828402184 0.003355333516566 0.0002481332774246 +Serine hydrolase activity 11 17 2.5077546852798767 0.012150098649547 6.934466019417476 18.83009708737864 1.2767207242593377 0.1489147276149277 2.386872767465543 1.965791668457755 1.709796217367629 0.2208345231085202 0.0342058213067418 1.0 0.0775813155228076 0.0284489140367958 0.0080473050001108 +Sphingolipid binding 4 6 2.4982327326152767 0.0124814220709832 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 0.0004315578367149 0.083126337411673 0.0126574737404708 0.0087554356838108 0.0013491401517078 +Sterol transporter activity 4 9 2.4884159463164344 0.0128313564156365 2.621359223300971 8.364077669902912 0.5454888897585024 0.2973249899153176 1.425267849835305 1.6080715320593837 1.318674977748992 0.2709274408896192 0.0544211779902942 0.1049896535105009 0.1993869387044997 0.1060727287920157 0.0043329575683166 +Antiporter activity 9 11 2.456466266686249 0.014031097456616 4.621359223300971 10.405339805825244 1.056576117278179 0.2813324268221227 2.679901841610502 1.304685592846984 1.2558310293487471 0.3063102364368053 0.1824170294817393 1.0 0.3143397790261298 0.0678108138951911 0.0106880220145335 +Metal ion transmembrane transporter activity 13 18 2.4561044988021803 0.0140452308812852 9.563106796116504 24.67233009708738 0.8657396859235934 0.3700615753207195 4.93288923178502 4.839352380624028 1.4450904591933955 0.3424002804304004 0.6839565394354321 1.0 0.6943670866160305 0.7995688785723946 0.382825590481106 +Gated channel activity 3 12 2.421868822824979 0.015440923214022 4.317961165048544 13.019417475728156 0.8697524591818097 0.2583579989367679 2.2914716766946497 2.0107989163575497 1.3733766112751231 0.2762671399351702 0.191529340247241 0.0335548880884004 0.0198486300115185 0.0571243888921134 0.3339856150584848 +Translation repressor activity mrna regulatory element binding 1 7 2.361229194034693 0.0182144696022505 1.5995145631067962 6.174757281553398 0.6534600204791633 0.3949783065671634 1.3392142882982137 0.7026604707853292 0.9849198932748844 0.2965869521608698 0.0734387458229045 1.0 1.0 0.0328731354880699 0.1129571724371578 +Voltage gated anion channel activity 2 6 2.324616752266602 0.0200924622178242 2.854368932038835 6.25 1.127126362633441 0.1649553590552043 1.5417035527207152 0.9966570336472054 1.4583344406160936 0.2334940994157564 0.0052965440152733 0.0470522829573702 0.0039135152062846 0.001485709034831 0.0106255777102749 +Fad binding 8 9 2.323518582028054 0.0201513105952542 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 0.01562494729998 1.0 1.0 0.0242110622206542 0.0012863968531589 +Endopeptidase activity 21 57 2.3163276224348226 0.020540387254879 19.08495145631068 62.800970873786405 1.5604938505680932 0.2935756148549138 5.629332570724372 6.156865220927466 1.27979578418692 0.359984229645684 0.0041631950397889 1.0 0.4761179790057352 0.0487648877657277 0.0011723818152273 +Atp transmembrane transporter activity 4 5 2.312444708907629 0.0207531889625154 3.058252427184466 5.456310679611651 0.5680189081478334 0.3318090311699867 1.598392655736251 0.6936144116307477 1.3025695117924114 0.3140848719976767 0.0026155774748029 1.0 1.0 0.0148625463558957 1.3236156489067347e-05 +Glycolipid binding 4 8 2.3070710816246223 0.0210508577826931 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 0.0003215953133908 0.0786913117950012 0.1515272625734178 0.062605312422627 0.0010145405611514 +Oxidoreduction driven active transmembrane transporter activity 9 27 2.3040136409628182 0.021221877866425 9.733009708737864 29.83252427184466 0.7626445826297276 0.3795490924215395 4.629116134249794 3.4519743101246267 1.4198222355288384 0.35536187545778 0.0022155464387141 0.2588687133858448 0.1194965359594502 0.0629955787418294 0.0007440053524939 +O acyltransferase activity 11 14 2.290237584761423 0.0220075477675485 4.711165048543689 12.395631067961164 0.9877600518928406 0.2684789023147002 2.6842893514436073 2.3496085895491885 1.2379749168209273 0.2720543739153138 0.1193311942579938 1.0 1.0 0.181169408752189 0.0181161163925661 +Organic acid transmembrane transporter activity 10 17 2.2736669669732086 0.0229860177221323 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.4783692141782226 0.2801168002074996 0.0275216398495969 0.2274506769816413 0.6495651864601311 +Protein carrier chaperone 6 12 2.2679240591466314 0.0233338356611798 3.3980582524271843 10.118932038834952 0.8288787693114796 0.3398938251553178 1.8569721980092944 2.0920401213092656 1.1849901066971258 0.3127406939001886 0.0004315578367149 0.083126337411673 0.0126574737404708 0.0007869115437374 0.0001445816257764 +Lipase activity 5 16 2.2445741458686563 0.0247954840553052 4.160194174757281 17.95145631067961 -0.3883889220249866 0.2447386375427953 2.2541370727794456 2.684470408535888 1.602380040893784 0.2433104127648577 0.0235594599921026 0.0325345581006573 0.1100932826860655 0.0029289523616429 0.0236488585480569 +Prenyltransferase activity 5 6 2.2418757240553715 0.024969405404994 2.099514563106796 6.009708737864078 0.6003375563696288 0.3888587975741492 1.4081247453019228 2.026499903013553 1.0962032128239394 0.3008779016140248 0.0174514302411212 0.0697581245313758 0.1349531130589082 0.0498779046475234 0.0005338561483377 +Anion channel activity 3 11 2.212918733892685 0.0269032488781524 4.20873786407767 11.21116504854369 1.03959259790327 0.2192420598609839 2.3076742714116403 2.0905640066649145 1.3937691950814175 0.2662450395835827 0.0036252861513815 0.0078974776787256 0.0023694947377154 0.0043549454623746 0.0103633783340074 +Amide transmembrane transporter activity 2 5 2.1706604930828464 0.0299568456639061 1.9781553398058251 4.745145631067961 1.408683964326367 0.195466717632665 1.3391087077639925 1.811666809674734 1.0002201259794938 0.2223338014085611 0.0380506123279191 0.0919337377678228 0.0155240337321844 0.0834574734746242 0.0705348016344186 +Exogenous protein binding 4 13 2.167094921374672 0.0302276170962569 4.509708737864078 15.157766990291265 0.7214109752050332 0.2527966464979699 2.499010078306418 1.9009100692398744 1.5211756979359785 0.2791170769282048 0.0894994943186356 1.0 1.0 0.6691111110298131 0.0660317196551079 +Inorganic anion transmembrane transporter activity 11 17 2.164758494139883 0.0304061849128725 7.427184466019417 19.274271844660195 1.0921593405593897 0.2441056926448881 3.717191605498929 3.7816647851785734 1.4014196343960104 0.2816216967014333 0.0132544128541003 0.0257535715284909 0.0015259573241502 0.0082403851981354 0.012384049701444 +Primary active transmembrane transporter activity 20 47 2.149037972928673 0.0316313899434019 17.696601941747574 52.529126213592235 1.0080198242353189 0.3544097082146772 7.649017203625277 6.455721193615876 1.66885648871365 0.3767837436492733 0.0057195117292442 0.4409382257745535 0.3210427924142759 0.1660809858489837 0.0020217277453714 +Solute anion antiporter activity 3 6 2.126949298958081 0.0334242960649913 2.3737864077669903 5.444174757281553 0.825822657258252 0.3439291028288794 1.663745987721657 0.8585888447978746 1.0247623924866192 0.2999489358207081 0.0627286747609657 1.0 1.0 0.027832231049335 0.00138858926748 +Hexosaminidase activity 2 5 2.123567862290248 0.0337062952704358 2.5194174757281553 4.973300970873787 0.3568105957806153 0.2227497456156347 1.091499214132507 0.3065083294438748 1.6445593916296413 0.2548912926080147 0.0038138415573948 1.0 1.0 0.0188064524051028 0.00771353919978 +Membrane insertase activity 5 9 2.1227884130100234 0.0337715862346572 2.737864077669903 7.388349514563107 0.8099367695235317 0.306513025583228 1.5809003521008822 1.7333564146948666 1.2685525479217892 0.3048480656363501 0.0014965097014554 0.0652597674910206 0.0077184558590264 0.0041946485896371 0.0003706302782608 +Organic cation transmembrane transporter activity 3 5 2.116429418777383 0.0343083022173362 1.9271844660194175 5.04126213592233 1.6158747778246996 0.14183106997637 1.275055237696066 0.9168044752551467 0.8418646651592007 0.1871331589544055 0.0143571981203825 1.0 0.1265462710440741 0.290751966651369 0.0037486095651754 +Palmitoyl protein hydrolase activity 2 5 2.1128105558982924 0.034616985825328 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0091783194539023 0.0561990347849709 0.0056684159955205 0.0328731354880699 0.0181181417645757 +Glycosyltransferase activity 17 45 2.094598533951064 0.0362066956565678 10.808252427184469 46.75 0.6230735361107147 0.5000303532444054 4.489970468729936 5.6981622825309435 0.9932734853426128 0.358363386747457 0.0796540748834645 1.0 1.0 0.0916349959305368 0.0461271240278972 +Translation repressor activity 4 10 2.0922119767614946 0.036419557592709 2.621359223300971 8.691747572815533 0.8178109552751379 0.3869214297451314 1.7535899646617803 1.1146116282865457 0.9030508481280868 0.2968248594231644 0.0431830308522053 1.0 1.0 0.090818300458346 0.0794376465838621 +Acylglycerol o acyltransferase activity 8 9 2.0442143878654084 0.0409323724212236 2.6601941747572817 6.820388349514563 0.8174935736497821 0.2734948556707107 1.708365471336677 1.514259678343348 1.2372108727630755 0.2654117957889352 0.1878361950417842 1.0 1.0 0.4028006685093745 0.0171177319456962 +Phospholipase activity 5 13 2.0280611606347327 0.0425540062682749 3.1990291262135924 15.094660194174756 -0.306546996035562 0.2833880814714293 1.8628194074527815 2.042811367353886 1.4121024393654518 0.2371187700906001 0.10726257004034 0.2068720246529641 0.371655018795122 0.0284489140367958 0.0824033164968481 +Nucleocytoplasmic carrier activity 8 20 1.9850737112661752 0.0471362711334928 7.444174757281553 19.67233009708738 0.0634206781641703 0.6193836320949039 4.186117840123668 1.6842823967514435 0.8882318111664522 0.3304839121824445 0.3008835791389011 0.1305522111527444 0.2445730022705269 0.5094216597603356 0.0501437556032915 +Mannose binding 4 7 1.9830640816709104 0.0473602720518471 2.487864077669903 6.235436893203883 0.6101269701833572 0.2582145467051042 1.3337836904766196 0.6757998162537485 1.36750331402198 0.2531492078603038 0.2657118944112667 1.0 1.0 0.1781979724676324 0.0544194668097373 +Lamin binding 3 8 1.9677759484143031 0.0490938227233621 3.174757281553398 8.133495145631068 0.8401140072225439 0.3634406451484216 1.8429987407927015 0.9675032512806204 0.9823145131994128 0.293984725882831 0.1085490453835639 1.0 1.0 0.307957256786686 0.0336357980244025 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ff2270b734739a89921291ea6d02be97355928ab --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 1359, + "title": "Average number of proteins per term", + "value": 15.952170713760118 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9dc0c74ccde0a5350daf6c687811b709a8480573 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7b7a358159d6674a90543053e96a2f7cef11cbad --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,376 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ion transmembrane transporter activity 0.5970537668687833 4.551736029908217 5.320506422989979e-06 0.0072045096569927 0.0036152841144223 96 Q14728,P98194,Q9BVC6,Q9HC21,P20020,P05141,Q6P4A7,P12236,Q9UDW1,Q9H2D1,P00846,Q7KZN9,Q00325,O43826,O43808,Q9H0U3,Q9C0H2,P24539,P12235,P45880,Q96ES6,Q9HD20,Q6NUK1,O00400,P13073,Q9P246,Q9UBX3,Q70HW3,Q9UM00,Q99808,O43681,Q9H936,P06576,O75964,P16615,Q9Y619,Q93050,O14548,P21796,P56385,Q9Y487,Q9HC07,P56134,Q9UJS0,O95202,Q9Y277,P05023,Q96S66,Q8N4V1,Q8TDW0,Q8TB61,Q13423,P55011 53 +Inorganic molecular entity transmembrane transporter activity 0.5863785481020328 4.10795568656376 3.9917666598388024e-05 0.0528039562686244 0.0160961297418109 71 P98194,P05141,P20020,P36543,Q9UDW1,O43826,Q7KZN9,P00846,Q00325,Q8NE86,Q9H0U3,Q9C0H2,P24539,P12235,P45880,Q96ES6,Q9HD20,O00400,P13073,Q9P246,Q9UM00,Q9UBX3,Q99797,O43681,Q9H936,P06576,O75964,P16615,Q93050,O14548,P51790,P21796,P56385,Q9Y487,Q9HC07,P56134,Q02978,O95202,P05023,Q9Y277,Q96S66,Q8N4V1,Q8TDW0,Q13423,P55011 45 +Cation transmembrane transporter activity 0.6041283987760867 4.068206468022426 4.73763936477134e-05 0.0623570419429366 0.0160961297418109 65 P98194,Q9HC21,P05141,P20020,Q9UDW1,Q7KZN9,P00846,Q00325,O43808,Q9H0U3,P24539,P12235,Q96ES6,Q9HD20,O00400,P13073,Q9P246,Q99808,Q70HW3,Q9UM00,Q9H936,P06576,O75964,P16615,Q9Y619,Q93050,O14548,P56385,Q9Y487,Q9HC07,P56134,O95202,P05023,Q8N4V1,Q13423,P55011 36 +Transporter activity 0.5778799573335217 3.984977233832483 6.748659564004278e-05 0.0876370333678208 0.0183428566949639 165 Q14728,P98194,Q9HC21,Q9NS69,Q9UGP8,Q99595,P05141,L0R6Q1,O96000,Q6P4A7,O60830,Q9H2C2,P12236,Q9UDW1,Q9H2D1,P00846,Q7KZN9,O43826,P61916,O43808,Q14849,Q9P0J0,Q9BSK2,Q9H0U3,Q9C0H2,P24539,P17900,P12235,P45880,O75438,Q96ES6,Q9HD20,Q6NUK1,O00400,P04062,O14925,P13073,Q03518,Q9UBX3,Q70HW3,Q99808,Q9P246,P03886,Q9Y584,Q07820,O75964,Q96GC9,P16615,Q9Y619,O43676,Q93050,P21796,P56385,Q9Y487,Q8WTV0,Q8NE01,Q9HC07,O75306,P38435,O96008,O95202,O95168,Q9Y5J9,O75027,Q9Y277,Q7L0J3,O15173,P05023,Q96SU4,Q8N4V1,Q8TDW0,Q8TB61,Q13423,O15118 74 +Anion transmembrane transporter activity 0.626301859692628 3.7404077629498143 0.0001837219585911 0.2209663831672934 0.0356683059607728 42 Q14728,Q9HC21,P05141,Q9C0H2,P12235,P45880,Q9Y277,P12236,Q6NUK1,O00400,Q9Y619,O43826,Q9H2D1,Q99808,P21796,Q8TDW0,Q8TB61,Q9UBX3 18 +Organophosphate ester transmembrane transporter activity 0.8628714151873995 3.571144002178774 0.0003554254040458 0.3831374083118514 0.0546606762393373 13 Q9BSK2,Q9HC21,P05141,P12235,P12236,Q6NUK1,O00400,O43826,Q9H2D1,Q8TB61,Q99808 11 +Organic anion transmembrane transporter activity 0.6908106818376423 3.539099450379955 0.0004014945647241 0.4205875329760252 0.0546606762393373 27 Q14728,Q9HC21,P05141,P12235,Q9UBX3,P12236,Q6NUK1,O00400,Q9Y619,Q9H2D1,Q8TB61,Q99808 12 +Nucleobase containing compound transmembrane transporter activity 0.8415358340068413 3.534833507957192 0.0004080321628554 0.4257146439544783 0.0546606762393373 14 Q9BSK2,Q9HC21,P05141,L0R6Q1,P12235,P12236,Q6NUK1,O00400,Q9H2D1,Q8TB61,Q99808 11 +Steroid binding 0.7363614210059697 3.5133862964414133 0.0004424337296782 0.4519564302632085 0.0546606762393373 22 Q14849,O95772,P38435,P35610,P45880,O00264,Q14108,P05023,O15173,P04062,Q96SU4,P21796,P61916,O15118 14 +Active ion transmembrane transporter activity 0.6078048059303639 3.4589650655073556 0.0005422552318443 0.5215122805094182 0.0614104050063748 39 P98194,P05141,P20020,P36543,P12236,Q9UDW1,O43826,Q7KZN9,Q00325,P12235,Q96ES6,Q9HD20,O00400,P13073,Q8N697,Q9H936,P06576,P51798,P16615,O14548,P51790,Q02978,O95202,P05023,P55011 25 +Nucleotide transmembrane transporter activity 0.8623788099390932 3.3847269389789076 0.000712490945177 0.6203935808479266 0.0681529805665304 12 Q9BSK2,Q9HC21,P05141,P12235,P12236,Q6NUK1,O00400,Q9H2D1,Q8TB61,Q99808 10 +Proton transmembrane transporter activity 0.5920632347297026 3.2769551584278727 0.0010493303295682 0.759921334196563 0.0681529805665304 38 P05141,Q9UDW1,Q7KZN9,P00846,Q00325,P24539,P12235,Q96ES6,O00400,P13073,Q9H936,P06576,O75964,Q93050,O14548,P56385,Q9Y487,P56134,O95202,Q13423 20 +Active transmembrane transporter activity 0.5159177613960234 3.2652109172350725 0.0010938259407775 0.7740232222146608 0.0681529805665304 67 P98194,P05141,P20020,P36543,O96000,P12236,Q9UDW1,O43826,Q7KZN9,Q00325,Q8NE86,P28288,Q9P0J0,P12235,O75438,Q96ES6,Q9HD20,P08183,O00400,Q15388,P13073,Q03518,Q9UBX3,Q8N697,P03886,Q9H936,P06576,P51798,P16615,O43676,O14548,P51790,O75306,Q02978,O95202,O95168,O75027,P05023,P55011 39 +Tetrapyrrole binding 0.7634989993527794 3.2625491829411217 0.0011041501152948 0.7771751022164127 0.0681529805665304 16 O43169,Q16850,P30519,P09601,P53701,O00264,O15173,Q6UW02,Q7KZN9 9 +Carbohydrate derivative transmembrane transporter activity 0.8343067722805042 3.241825701643869 0.0011876663570344 0.8011088936780683 0.0681529805665304 12 P05141,L0R6Q1,P12235,P12236,Q6NUK1,O00400,O43826,Q8TB61,Q99808 9 +Protein transporter activity 0.7725601489072307 3.2347187940311484 0.0012176258887777 0.8090534698112724 0.0681529805665304 15 Q9NS69,Q9UGP8,Q9Y584,Q99595,Q07820,O96008,O60830,Q9Y5J9,Q9HD20,O14925 10 +Snap receptor activity 0.7196003946476539 3.226979871538149 0.0012510426042744 0.8175412716635397 0.0681529805665304 19 Q86Y82,P56962,Q13190,O14653,O43752,Q9P2W9,Q13277,O75396,Q9UEU0,Q12981,O15155,O95249,O15400 13 +Secondary active transmembrane transporter activity 0.6859481401587327 3.128512229597274 0.0017569369939349 0.9083499110481816 0.0855818899853259 21 Q8N697,Q9H936,P05141,Q02978,P12235,O95202,Q9UBX3,P51798,Q96ES6,P12236,P08195,O00400,P51790,O43826,Q15758,Q00325,Q8NE86,P55011 18 +Sterol binding 0.7057848755666647 3.003182912590212 0.0026717180069071 0.9736351541098625 0.1252022334960963 17 Q14849,O95772,P35610,P45880,Q14108,Q96SU4,P21796,P61916,O15118 9 +Macromolecule transmembrane transporter activity 0.7401188334896542 2.9776227352236826 0.0029049330973744 0.9808135170641902 0.1273944943476631 14 Q9NS69,Q9UGP8,Q9Y584,Q99595,Q07820,O96008,O60830,O14925 8 +Protein transmembrane transporter activity 0.7805697390797975 2.960948046748091 0.0030669366919886 0.9846151421236716 0.1273944943476631 12 Q9NS69,Q9UGP8,Q9Y584,Q99595,Q07820,O96008,O60830,O14925 8 +Monooxygenase activity 0.9122658610302592 2.8961065479099073 0.0037782409492488 0.9941677585576578 0.1273944943476631 8 Q14534,P30519,P09601,Q15800,Q9BU89,Q6UW02 6 +Cholesterol binding 0.7196703359828374 2.8604606182152845 0.0042302608959259 0.996852411530722 0.1273944943476631 14 Q14849,O95772,P35610,P45880,Q14108,P21796,P61916,O15118 8 +Purine nucleotide transmembrane transporter activity 0.8589990177412659 2.842106075761059 0.0044816577370108 0.9977666703947772 0.1273944943476631 9 P05141,P12235,P12236,Q6NUK1,O00400,Q8TB61,Q99808 7 +Alcohol binding 0.6563045564921981 2.776995946800286 0.0054863863138672 0.9994337797180596 0.12988433434822 18 O95772,Q14849,P35610,P45880,Q14108,O94905,P21796,P61916,O15118 9 +Passive transmembrane transporter activity 0.5560014489552887 2.7196297567984513 0.0065355047685546 0.99986508983175 0.1424416236196128 32 Q9BVC6,P00846,Q8NE86,Q9C0H2,P24539,P45880,Q9P246,Q9UM00,Q99797,P06576,O75964,P51790,P21796,P56385,P56134,O96008,Q9Y277,Q96S66,Q8TDW0 19 +Molecular carrier activity 0.5390495296561334 2.6978516700975654 0.0069788528937826 0.9999264474542934 0.1424416236196128 35 Q5J8M3,Q9C0E2,Q8N8Q8,P55060,O75880,Q9NPA0,O43819,Q53FT3,Q8TEX9,Q92973,P62072,O00410,Q15006,P52292,Q15070,Q9HAV4,P40855,Q8N4V1,Q96P70 19 +Metalloendopeptidase activity 0.66674605546961 2.615115104436153 0.0089197390218338 0.9999948489561912 0.1554092991111821 15 P42892,Q96E52,O75844,Q5JRX3 4 +Hydrolase activity hydrolyzing o glycosyl compounds 0.6068249369052372 2.5994877104776393 0.0093363021448635 0.9999970908090384 0.1606080330996153 21 P06280,P16278,P04066,P17900,Q9NUJ1,P10253,P04062,P06865,Q9BTY2,P08236,P54802 11 +Sulfur compound transmembrane transporter activity 0.8687083334332542 2.5617757333722286 0.0104138540097877 0.99999933709483 0.1672853862739005 6 O00400,Q9UBX3,Q70HW3,Q8TB61 4 +Hexosyltransferase activity 0.5268873425810994 2.5555839359857555 0.0106009790303709 0.9999994873319276 0.1672853862739005 34 Q6ZXV5,O43505,P04844,Q96L58,Q10472,P46976,Q13126,O43909,Q9BV10,P04062,P15291,Q10471,P06865,Q9BT22,P46977 15 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.5255803995384701 2.544576855572911 0.0109410231703732 0.9999996786673364 0.1672853862739005 34 Q16850,Q14534,P30519,P09601,Q15800,Q9BU89,P16435,P07237,Q6UW02 9 +Vitamin transmembrane transporter activity 0.8624182661079272 2.5339575855607768 0.0112782381982043 0.9999997978412604 0.1672853862739005 6 P38435,P04062,Q9H2D1 3 +Molecular transducer activity 0.541460754090834 2.5333982482233477 0.0112962531052032 0.999999802785597 0.1672853862739005 30 Q9BUN8,Q08AM6,Q99720,Q9Y6I9,Q08722,O15173,Q15629,Q8WTV0,O15118 9 +Ceramide binding 0.9143327841845106 2.5219448145845176 0.0116708015911612 0.9999998821553856 0.1672853862739005 5 Q9UM22,Q9NZJ7,P45880,P21796 4 +Serine hydrolase activity 0.6267863371898349 2.5077546852798767 0.012150098649547 0.9999999390441 0.1684896333136172 17 O43464,Q4J6C6,Q16740,Q9HB40,P42785,Q5JRX3,P10619,P67812,Q9H3G5,P53634,O14773 11 +Sphingolipid binding 0.8543714816425003 2.4982327326152767 0.0124814220709832 0.9999999613607896 0.1702425543492468 6 Q9UM22,Q9NZJ7,P45880,P21796 4 +Sterol transporter activity 0.7849785837457042 2.4884159463164344 0.0128313564156365 0.9999999761302788 0.1702425543492468 9 Q14849,Q96SU4,Q9H2C2,O15118 4 +Antiporter activity 0.7150959077392841 2.456466266686249 0.014031097456616 0.9999999954279328 0.1767358219228398 11 P05141,Q02978,P12235,O95202,P51798,P12236,P51790,O43826,Q9UBX3 9 +Metal ion transmembrane transporter activity 0.6072412125274326 2.4561044988021803 0.0140452308812852 0.9999999955161384 0.1767358219228398 18 Q9HC07,P98194,Q9H0U3,Q8NE86,P20020,O95202,P16615,Q9HD20,P05023,Q8N4V1,Q9P246,Q9UM00,P55011 13 +Gated channel activity 0.6825657803151955 2.421868822824979 0.015440923214022 0.9999999993459974 0.1887790038352382 12 Q9C0H2,P45880,P21796 3 +Translation repressor activity mrna regulatory element binding 0.8020548076716887 2.361229194034693 0.0182144696022505 0.9999999999858552 0.2062788682454879 7 Q9BPZ3 1 +Voltage gated anion channel activity 0.8157538098167794 2.324616752266602 0.0200924622178242 0.9999999999989516 0.217346278563099 6 P45880,P21796 2 +Fad binding 0.751567139557884 2.323518582028054 0.0201513105952542 0.9999999999990338 0.217346278563099 9 Q14534,O15254,O00116,P00387,Q15067,Q8NB78,Q15392,Q96HE7 8 +Endopeptidase activity 0.4472268551109903 2.3163276224348226 0.020540387254879 0.9999999999994368 0.2197983171604774 57 Q99538,Q96E52,Q10713,O14773,P49721,P67812,O75844,Q99797,Q4J6C6,Q96K76,P28070,P42892,Q9NZ08,Q5JRX3,Q8TCT8,Q92542,P28072,Q92643,Q16740,Q9BXS4,Q8TCT9 21 +Atp transmembrane transporter activity 0.8649093904448067 2.312444708907629 0.0207531889625154 0.9999999999995808 0.2201567329806995 5 P05141,P12236,Q6NUK1,P12235 4 +Glycolipid binding 0.7831260292762425 2.3070710816246223 0.0210508577826931 0.9999999999997228 0.2201567329806995 8 P07602,Q9UM22,Q9NZJ7,P50897 4 +Oxidoreduction driven active transmembrane transporter activity 0.52380311565021 2.3040136409628182 0.021221877866425 0.9999999999997812 0.2201567329806995 27 Q9P0J0,O75306,P03886,O96000,O75438,O43676,Q9UDW1,Q7KZN9,P13073 9 +O acyltransferase activity 0.6242510199277642 2.290237584761423 0.0220075477675485 0.9999999999999264 0.2231285577455564 14 P50416,Q86UL3,P35610,Q8NCC3,Q96N66,Q9NUQ2,Q7L5N7,P23786,Q99943,Q8NF37,Q92604 11 +Organic acid transmembrane transporter activity 0.5910699948672078 2.2736669669732086 0.0229860177221323 0.9999999999999812 0.2231285577455564 17 Q8N697,Q9H936,Q9UJS0,Q02978,Q15758,Q9Y619,P08195,P08183,Q9H2D1,Q9UBX3 10 +Protein carrier chaperone 0.655751789457895 2.2679240591466314 0.0233338356611798 0.9999999999999885 0.2248984586066909 12 P40855,P62072,Q15006,Q8N8Q8,Q8N4V1,Q15070 6 +Lipase activity 0.5971267363210351 2.2445741458686563 0.0247954840553052 0.9999999999999984 0.2324206982560746 16 P09601,Q8NCG7,Q9NP80,Q9H6V9,Q8IV08 5 +Prenyltransferase activity 0.7976268951878598 2.2418757240553715 0.024969405404994 0.9999999999999988 0.2324206982560746 6 Q5T2R2,Q86SQ9,P14324,P49356,P37268 5 +Anion channel activity 0.6708144412347472 2.2129187338926855 0.0269032488781524 1.0 0.2453350726139074 11 Q9C0H2,P45880,P21796 3 +Amide transmembrane transporter activity 0.8321234361358997 2.1706604930828464 0.0299568456639061 1.0 0.2582625331037108 5 O00400,Q9H2D1 2 +Exogenous protein binding 0.6135576044341472 2.167094921374672 0.0302276170962569 1.0 0.2582625331037108 13 Q14108,Q8WTV0,P11279,O15118 4 +Inorganic anion transmembrane transporter activity 0.5747848508984557 2.164758494139883 0.0304061849128725 1.0 0.2582625331037108 17 O43681,Q9C0H2,P45880,Q9Y277,Q96S66,P51790,O43826,P21796,Q8TDW0,Q9UBX3,P55011 11 +Primary active transmembrane transporter activity 0.4439517180516973 2.149037972928673 0.0316313899434019 1.0 0.2637242879330263 47 P98194,P20020,O96000,Q9UDW1,Q7KZN9,P28288,Q9P0J0,O75438,Q9HD20,Q15388,Q03518,P13073,P03886,P16615,O43676,O14548,O75306,O95168,O75027,P05023 20 +Solute anion antiporter activity 0.7727342388256382 2.126949298958081 0.0334242960649913 1.0 0.2714911429415461 6 P05141,P12236,P12235 3 +Hexosaminidase activity 0.8213465239106305 2.123567862290248 0.0337062952704358 1.0 0.2714911429415461 5 P17900,P06865 2 +Membrane insertase activity 0.7117866048681125 2.1227884130100234 0.0337715862346572 1.0 0.2714911429415461 9 P62072,Q15006,Q8N8Q8,Q8N4V1,Q15070 5 +Organic cation transmembrane transporter activity 0.8197176978490952 2.116429418777383 0.0343083022173362 1.0 0.2726607176219883 5 Q9HC21,Q70HW3,Q99808 3 +Palmitoyl protein hydrolase activity 0.8188924333931208 2.1128105558982924 0.034616985825328 1.0 0.2735144403291906 5 P50897,Q9UMR5 2 +Glycosyltransferase activity 0.4403506539391897 2.0945985339510633 0.0362066956565678 1.0 0.2796281286355461 45 Q6ZXV5,O43505,P43490,Q8IXJ6,Q96L58,P04844,Q10472,P46976,Q13126,O43909,Q9BV10,P04062,P15291,Q10471,P06865,Q9BT22,P46977 17 +Translation repressor activity 0.6722189060210212 2.0922119767614946 0.036419557592709 1.0 0.2796281286355461 10 P00374,Q9BPZ3,Q5PRF9,Q14011 4 +Acylglycerol o acyltransferase activity 0.6964698119432401 2.0442143878654084 0.0409323724212236 1.0 0.2996419405108068 9 Q86UL3,Q8NCC3,Q96N66,Q9NUQ2,Q7L5N7,Q99943,Q8NF37,Q92604 8 +Phospholipase activity 0.5911087013485408 2.0280611606347327 0.0425540062682749 1.0 0.2996419405108068 13 P09601,Q8NCC3,Q8NHP8,Q9NP80,Q8IV08 5 +Nucleocytoplasmic carrier activity 0.5270032396771486 1.9850737112661752 0.0471362711334928 1.0 0.3183686046574937 20 Q53FT3,Q8TEX9,Q92973,Q9C0E2,P55060,Q96P70,Q9HAV4,P52292 8 +Mannose binding 0.7225052495710236 1.9830640816709104 0.0473602720518471 1.0 0.3183686046574937 7 P35613,Q12907,O60762,O75503 4 +Lamin binding 0.7128436215224253 1.9677759484143031 0.0490938227233621 1.0 0.3227016327720563 8 Q14739,O94901,P42167 3 +Hydrolase activity acting on glycosyl bonds 0.4719872407282693 1.9310105454191808 0.0534817483214862 1.0 0.3380543998553478 29 P06280,P16278,P54802,P04066,P17900,Q9NUJ1,P10253,P04062,P06865,Q9BTY2,P08236,O75503 12 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.9888084265964436 1.9236635497818748 0.0543967697252369 1.0 0.3392558075600367 2 P09601 1 +Voltage gated channel activity 0.6414436812964954 1.9234725904094472 0.0544207255688653 1.0 0.3392558075600367 10 P45880,P21796 2 +Solute cation symporter activity 0.727422544495701 1.9139122595538072 0.0556313676722566 1.0 0.3405541831828683 6 Q9H936,Q96ES6,O00400,Q00325,P55011 5 +Lysophospholipid acyltransferase activity 0.6962401055408914 1.8856617554841004 0.0593405496860222 1.0 0.3600169956397507 8 Q86UL3,Q96N66,Q9NUQ2,Q7L5N7,Q99943,Q8NF37,Q92604 7 +Nuclear import signal receptor activity 0.5892769483422985 1.8738177638237177 0.060955547138332 1.0 0.3657350344890557 12 Q53FT3,Q8TEX9,Q92973,Q96P70,P52292 5 +Serine type exopeptidase activity 0.6928888933307018 1.8380681689585403 0.0660523609295102 1.0 0.3740917662392723 7 Q9HB40,P42785,P10619,Q9H3G5,O14773 5 +Symporter activity 0.6833819333784243 1.8215658974520204 0.0685208793547558 1.0 0.3758082754012725 8 Q8N697,Q9H936,Q96ES6,O00400,Q00325,P55011 6 +Cargo receptor activity 0.6882675329571999 1.8152428649626984 0.0694865950111665 1.0 0.377729130480701 7 O15260,P02786,Q14108,Q5JRA6,Q8WTV0 5 +Udp glycosyltransferase activity 0.5405200751278849 1.809885345048836 0.070313569219528 1.0 0.3789076806486144 15 O43505,Q96L58,Q10472,P46976,O43909,P06865,P15291 7 +Oxidoreductase activity acting on nad p h 0.4606538438404501 1.766033268979155 0.0773902675399818 1.0 0.3998987588853051 26 Q9P0J0,O75306,P03886,O96000,O75438,P16435,P00387,O43676,Q7KZN9,Q13423 10 +Calcium ion binding 0.352042032414156 1.75320251722419 0.079567251103195 1.0 0.4050264630848962 82 P27824,O95302,Q02818,Q8NF37,P41208,Q96A33,P80303,Q14257,Q9Y680,Q6NUK1,Q9P246,Q9NWM8,O75071,P0DP25,P16615,O43852,Q8IYU8,Q9BRK5,P04083,Q9UM22 20 +Phospholipase d activity 0.9483212639894588 1.753158900405381 0.0795747355729707 1.0 0.4050264630848962 2 P09601 1 +Adp transmembrane transporter activity 0.8646245059288626 1.7507009444687562 0.0799974366709623 1.0 0.4056586434173055 4 P05141,P12236,P12235 3 +Peptidase activator activity 0.6097653209377897 1.7464319674706976 0.0807359191545786 1.0 0.4078814651712729 10 Q9BXK5,P05067,P53634,P61289 4 +Serine type carboxypeptidase activity 0.7308072487644028 1.7187646062509274 0.0856572426897996 1.0 0.4181995070427953 5 Q9HB40,P42785,P10619,Q9H3G5 4 +Wide pore channel activity 0.855480120657689 1.7130918097875782 0.0866956505604754 1.0 0.4181995070427953 4 P45880,P21796 2 +Porin activity 0.855480120657689 1.7130918097875782 0.0866956505604754 1.0 0.4181995070427953 4 P45880,P21796 2 +Solute proton symporter activity 0.7271828665568241 1.702239063074384 0.0887105627794173 1.0 0.4181995070427953 5 Q96ES6,Q00325,O00400,Q9H936 4 +Calcium ion transmembrane transporter activity 0.5396518196393087 1.701069385599919 0.0889299588269429 1.0 0.4181995070427953 13 Q9HC07,P98194,Q8NE86,P20020,O95202,P16615,Q9P246,Q9UM00 8 +Mannosyltransferase activity 0.6829500692300456 1.7001769697626532 0.0890976428382321 1.0 0.4181995070427953 6 Q6ZXV5,Q9BT22,Q9BV10 3 +Er retention sequence binding 0.9354838709677332 1.6988344285033028 0.0893503846694105 1.0 0.4181995070427953 2 P24390 1 +Quaternary ammonium group binding 0.5604226474508152 1.6972769305432944 0.0896443166062574 1.0 0.4181995070427953 12 P45880,P21796,A1L0T0 3 +Beta n acetylhexosaminidase activity 0.8498812513934726 1.6900169217398722 0.0910247173305465 1.0 0.4181995070427953 4 P17900 1 +Cytochrome b5 reductase activity acting on nad p h 0.9321922317314024 1.684888705552279 0.0920100460675372 1.0 0.4181995070427953 2 P16435 1 +Nitrite reductase activity 0.9321922317313912 1.6848887055522306 0.0920100460675465 1.0 0.4181995070427953 2 O43169 1 +Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor 0.9321922317313912 1.6848887055522306 0.0920100460675465 1.0 0.4181995070427953 2 O43169 1 +Phosphatidylcholine binding 0.653355941353247 1.6702242756498864 0.0948749987665167 1.0 0.4239725128427682 8 P45880,P21796 2 +Proton channel activity 0.5747177124725311 1.6595381393056028 0.0970074019371576 1.0 0.4269209925478047 11 P24539,P00846 2 +Proton transporting atp synthase activity rotational mechanism 0.5747177124725311 1.6595381393056028 0.0970074019371576 1.0 0.4269209925478047 11 P24539,P00846 2 +Vitamin d binding 0.9256089532587232 1.6569794411105243 0.0975236316816334 1.0 0.4269209925478047 2 P04062 1 +Quinone binding 0.716985464458894 1.6556238696767425 0.0977980132055083 1.0 0.4269209925478047 5 O75306,Q8N0U8,P21912 3 +Peptide antigen binding 0.715537990553408 1.6489930665679036 0.0991490551552796 1.0 0.4269209925478047 5 P04439,Q03518,Q15392 3 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.8369565217391342 1.6366178513104055 0.101710343271536 1.0 0.4319511140813046 4 Q96HE7,P07237,Q9UHG3 3 +Lipid transfer activity 0.7111104590558521 1.628689728291076 0.1033787183146812 1.0 0.43325425305825 5 Q14849,P61916 2 +Transition metal ion transmembrane transporter activity 0.8313570487483649 1.6134291286482618 0.106651308993372 1.0 0.438245736109793 4 Q9HD20,Q9HC07,Q8N4V1 3 +Cation channel activity 0.4862457626704258 1.6100362536852857 0.1073899420021553 1.0 0.438245736109793 18 P56134,Q8NE86,P24539,P06576,O75964,P00846,P56385,Q9P246,Q9UM00 9 +N6 methyladenosine containing rna binding 0.6446756805403208 1.5974105353570252 0.1101742255762276 1.0 0.4390814444518868 7 Q7Z739,Q9BYJ9,Q9Y5A9,P22626 4 +Palmitoyltransferase activity 0.7028006589785707 1.590499957838821 0.1117221551210401 1.0 0.4439485637704488 5 P50416,P23786,O15269,O15270 4 +Amino acid transmembrane transporter activity 0.6355440188686821 1.5793911574312385 0.1142463643460565 1.0 0.4473212991674236 8 Q8N697,Q9H936,Q9UJS0,Q9Y619,P08195 5 +L amino acid transmembrane transporter activity 0.6355440188686821 1.5793911574312385 0.1142463643460565 1.0 0.4473212991674236 8 Q8N697,Q9H936,Q9UJS0,Q9Y619,P08195 5 +Sulfatide binding 0.9071757735352068 1.57872867410668 0.1143983048393855 1.0 0.4473212991674236 2 P50897 1 +Lysophosphatidic acid binding 0.9071757735352068 1.57872867410668 0.1143983048393855 1.0 0.4473212991674236 2 P50897 1 +Dicarboxylic acid transmembrane transporter activity 0.640654178513026 1.5770957088683917 0.1147735044489706 1.0 0.4473212991674236 7 Q02978,Q9H936,Q9UJS0,Q9UBX3 4 +Electron transfer activity 0.3856550998377542 1.5759876584382686 0.1150286474723754 1.0 0.4473212991674236 51 Q9P0J0,O75306,P03886,Q9Y6N1,O96000,O75438,O95168,P16435,O43676,P14406,Q9UDW1,Q7KZN9,P21912,P13073 14 +C4 dicarboxylate transmembrane transporter activity 0.6567715495925835 1.5723799107874716 0.1158624704245276 1.0 0.4473212991674236 6 Q02978,Q9H936,Q9UJS0,Q9UBX3 4 +Galactosidase activity 0.9035549703752472 1.563343885189847 0.1179717312661017 1.0 0.4496616086387565 2 P06280 1 +Galactoside binding 0.9035549703752472 1.563343885189847 0.1179717312661017 1.0 0.4496616086387565 2 P06280 1 +Aspartic type peptidase activity 0.8188655090077759 1.561589229611124 0.1183847883602737 1.0 0.4496616086387565 4 Q8TCT9,Q8TCT8 2 +Lysophospholipase activity 0.6962887246049816 1.5604993953493351 0.1186419127452276 1.0 0.4496616086387565 5 Q9NP80 1 +2 acylglycerol 3 phosphate o acyltransferase activity 0.6955518945634164 1.5571008859397364 0.1194465347451001 1.0 0.4496616086387565 5 Q96N66,Q8NF37,Q7L5N7,Q92604 4 +Signal recognition particle binding 0.6922504785479916 1.5418640832898378 0.1231066254935189 1.0 0.4581605499694606 5 Q9UHB9 1 +Amyloid beta binding 0.6280170648522945 1.5407842368831717 0.1233693071125765 1.0 0.4581605499694606 8 Q8WTV0 1 +Oxidoreductase activity acting on a heme group of donors 0.6330906292104359 1.538794781068433 0.1238544043827365 1.0 0.4581605499694606 7 P13073,Q7KZN9,P16435 3 +Mhc class ib protein binding 0.896971691902557 1.5353633523954913 0.1246946004376734 1.0 0.4581605499694606 2 Q9NUQ9 1 +Growth factor receptor binding 0.492014411952603 1.5331857609599648 0.1252300916107018 1.0 0.4581605499694606 16 O00560,Q3ZCQ8,Q92600,Q9Y639,Q9NZ08,Q92542,P05067 7 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.9160355614092822 1.518631145956705 0.1288553667785854 1.0 0.4581605499694606 3 Q14534,Q15800 2 +Signal sequence binding 0.4287428481699774 1.515684161794041 0.1295992343724279 1.0 0.4581605499694606 27 O43731,Q9Y584,P24390,Q92973,P40855,Q9UHB9 6 +Mhc protein binding 0.5961981732158087 1.5126611820967262 0.1303657445514006 1.0 0.4581605499694606 9 Q9BUN8,Q03518,P51572,Q9NUQ9 4 +Ganglioside binding 0.9137306552518903 1.5096039639921186 0.1311445092821876 1.0 0.4581605499694606 3 Q9UM22,Q9NZJ7 2 +Glycosphingolipid binding 0.9137306552518903 1.5096039639921186 0.1311445092821876 1.0 0.4581605499694606 3 Q9UM22,Q9NZJ7 2 +Metallopeptidase activity 0.3837302929673923 1.5064366341004432 0.1319551223013741 1.0 0.4581605499694606 44 P09960,Q5JRX3,P42892,Q96E52,Q9UIQ6,Q10713,Q9NZ08,O75844,Q969V3 9 +Oxidoreductase activity acting on nad p h heme protein as acceptor 0.9091208429371066 1.4915437989005005 0.1358187809643989 1.0 0.465037084944953 3 P16435,P00387 2 +Peptide binding 0.3593163291251716 1.4758212404421982 0.139991887105765 1.0 0.4661812812250661 66 P24390,Q9Y584,O43731,Q92973,Q9UHB9,P40855,P55786,O00264,P42892,Q9UIQ6,Q15392,Q9NZ08,Q03518,O14773,Q8WTV0 15 +Sulfotransferase activity 0.7954545454545653 1.4640760696236708 0.1431731649594185 1.0 0.4692623857073927 4 Q9NRB3,Q8NCH0,Q7LGA3 3 +Atpase binding 0.4220142393470531 1.4575588496981304 0.1449621791242366 1.0 0.4692623857073927 27 Q9BUN8,Q8IZL8,P40855,O76024,Q93050,Q9Y487,Q92542 7 +Nadh dehydrogenase activity 0.4610715383727913 1.4575321712547935 0.1449695375429687 1.0 0.4692623857073927 19 Q9P0J0,O75306,P03886,O96000,O75438,O43676 6 +P type transmembrane transporter activity 0.7875494071146304 1.431061098876443 0.1524127050330188 1.0 0.4696937284899276 4 P05023,P16615,P98194 3 +Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity 0.8722843976300203 1.4303998877195825 0.152602280470762 1.0 0.4696937284899276 2 O43505 1 +Catalytic activity acting on a glycoprotein 0.8722843976300203 1.4303998877195825 0.152602280470762 1.0 0.4696937284899276 2 O43505 1 +Beta 1 3 galactosyltransferase activity 0.8722843976300203 1.4303998877195825 0.152602280470762 1.0 0.4696937284899276 2 O43505 1 +G protein activity 0.4977785770009022 1.4269716793331426 0.153588057991109 1.0 0.4696937284899276 13 Q15907,P61225,P61026 3 +Oxidative phosphorylation uncoupler activity 0.8712969058591074 1.4262020387530998 0.1538100313270787 1.0 0.4696937284899276 2 P12235 1 +Nucleobase transmembrane transporter activity 0.8712969058591074 1.4262020387530998 0.1538100313270787 1.0 0.4696937284899276 2 P12235 1 +Glutathione transferase activity 0.6261967897528566 1.4215068553383088 0.1551694620495682 1.0 0.4713554466029898 6 O43708,P78417 2 +Oxidoreductase activity acting on other nitrogenous compounds as donors 0.8899239675539748 1.4162713357661465 0.1566960768890564 1.0 0.474276099091821 3 O43169 1 +Aspartic endopeptidase activity intramembrane cleaving 0.8857425090549835 1.3998666801661512 0.1615532454751336 1.0 0.4814711855278653 3 Q8TCT9,Q8TCT8 2 +Snare binding 0.4021560951877808 1.388848550881091 0.1648788081206982 1.0 0.4818716134108147 32 Q86Y82,P56962,Q13190,P49755,O14653,O43752,Q13277,Q9UEU0,Q9P253,O15400 10 +Scavenger receptor activity 0.7768439234547124 1.38629543021574 0.1656567116860228 1.0 0.4826590211209163 4 Q8WTV0 1 +Magnesium ion transmembrane transporter activity 0.86175115207373 1.385634476576325 0.165858545153398 1.0 0.4826590211209163 2 Q8N4V1 1 +Phospholipase a1 activity 0.8604344963791801 1.3800410662604268 0.1675740010274338 1.0 0.4866091183681251 2 Q9NP80 1 +Atpase coupled cation transmembrane transporter activity 0.4903054534606993 1.3773896923141165 0.1683917980094935 1.0 0.4879412654475517 13 P98194,P20020,P06576,P16615,Q9HD20,P05023 6 +Procollagen proline dioxygenase activity 0.6549480586527908 1.368743147991936 0.1710795776730651 1.0 0.4923431644200251 5 P07237,P13674 2 +Mitochondrial ribosome binding 0.7720854156548431 1.3663805029283091 0.1718195651304737 1.0 0.4926219177474973 4 Q15070 1 +Phosphatidylinositol kinase activity 0.6525031601393105 1.3573440824963434 0.1746719066111763 1.0 0.4997455180728183 5 Q8NEB9 1 +Acid phosphatase activity 0.768994711456765 1.3534409367849138 0.1759148068759641 1.0 0.5012858319107987 4 Q9NPH0 1 +Nadp retinol dehydrogenase activity 0.6453544552682156 1.3239855295610228 0.1855078505835852 1.0 0.5174744230289531 5 Q9HBH5,Q8NBN7 2 +G protein alpha subunit binding 0.6434533475629647 1.3151076783799616 0.1884737164087031 1.0 0.5178943996588903 5 P80303 1 +Oligosaccharyl transferase activity 0.7595436355675453 1.3138552945812747 0.1888949055328987 1.0 0.5178943996588903 4 P04844 1 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.7595436355675453 1.3138552945812747 0.1888949055328987 1.0 0.5178943996588903 4 P04844 1 +Lipid binding 0.3561472670844002 1.310605901306137 0.1899909444412544 1.0 0.5178943996588903 138 P07602,Q9NZJ7,Q9BQE5,O60784,Q14108,Q96E52,P50897,O14773,P61916,Q14849,O15254,Q8NCC3,P45880,O00264,P04062,O00560,O95772,A6NIH7,P28070,O60313,Q15067,Q9BWH2,P21796,Q8WTV0,P38435,Q96L92,Q13277,Q9NQZ5,O15173,Q96SU4,P04083,Q9UM22,O15118 33 +Lipid transporter activity 0.4415921121045646 1.310101879696984 0.1901613726488493 1.0 0.5178943996588903 19 Q14849,P17900,Q9H2C2,Q96GC9,Q96SU4,O15118 6 +O methyltransferase activity 0.587682043825176 1.3065789939711203 0.191355734621045 1.0 0.5201048867000004 7 O60725 1 +Heme transmembrane transporter activity 0.8377221856484325 1.2836887479605554 0.1992508830226822 1.0 0.5321437266396768 2 O15173 1 +Ribosomal protein s6 kinase activity 0.8357472021066377 1.275326216878231 0.2021938020269671 1.0 0.5366823768645476 2 P51812 1 +Phosphatidyl phospholipase b activity 0.8506324549280552 1.2621591329318662 0.2068915307383589 1.0 0.5437035229504517 3 Q9NP80 1 +Calcium channel regulator activity 0.6320580008861842 1.2618453357345845 0.2070044452207016 1.0 0.5437035229504517 5 P62942 1 +Transferase activity transferring alkyl or aryl other than methyl groups 0.4299810234128224 1.2536892937066102 0.209954960886799 1.0 0.5476560304129747 20 Q5T2R2,Q86SQ9,Q99735,P78417,P53611,P14324,P49356,O43708,P37268 9 +Ubiquitin conjugating enzyme binding 0.5470131992162987 1.2424333110513248 0.2140767316291021 1.0 0.5529020990539169 9 Q92564 1 +Exopeptidase activity 0.3811915457871847 1.2422915386239186 0.2141290161102054 1.0 0.5529020990539169 34 Q92820,Q9HB40,P55786,P09960,O14773,Q9UIQ6,P10619,Q9H3G5,Q9NZ08,O75844,Q969V3 11 +Glycosaminoglycan binding 0.4436532640916669 1.2397761065708262 0.2150582181291056 1.0 0.5529020990539169 17 O14737,P15586,Q53GQ0,P05067 4 +Atpase coupled transmembrane transporter activity 0.4272122279319253 1.2321860342606032 0.2178795989815636 1.0 0.5544913389811703 20 P98194,P20020,P36543,P06576,O75027,P16615,Q9HD20,P05023,P08183,Q15388,Q03518,P28288 12 +Hydrolase activity acting on ether bonds 0.5872172215172883 1.2272265182534423 0.219737465072372 1.0 0.557132863868197 6 P07099 1 +Fk506 binding 0.5718041256173239 1.2246439187444604 0.2207094127169719 1.0 0.5575094799336325 7 Q9Y680 1 +Macrolide binding 0.5718041256173239 1.2246439187444604 0.2207094127169719 1.0 0.5575094799336325 7 Q9Y680 1 +Protein lipid complex binding 0.7367062742398922 1.218157974479582 0.2231639463767851 1.0 0.5575094799336325 4 Q9BQE5 1 +Thiol oxidase activity 0.8366809351333515 1.207540440289194 0.2272240807226282 1.0 0.5584042056094969 3 Q96HE7,P07237 2 +Manganese ion transmembrane transporter activity 0.8310833058939653 1.185657962857231 0.2357574018954742 1.0 0.5691051322117789 3 Q9HD20,Q9HC07 2 +17 beta hydroxysteroid dehydrogenase nadpplus activity 0.8130348913759027 1.1794317546457844 0.2382262967744806 1.0 0.569244162310235 2 Q53GQ0 1 +Peptidyl proline dioxygenase activity 0.5769849112531279 1.1759955350583515 0.2395966602744197 1.0 0.569244162310235 6 P07237,P13674 2 +Nadplus binding 0.5767631095787535 1.1748844162187833 0.2400409610915366 1.0 0.569244162310235 6 Q16836,Q8IXJ6,P40939 3 +Sterol transfer activity 0.8275994149188928 1.1720498372489534 0.2411770477933914 1.0 0.569244162310235 3 Q14849 1 +Carnitine o acyltransferase activity 0.8097432521395419 1.1655850178297382 0.2437822681858401 1.0 0.569244162310235 2 P23786 1 +O palmitoyltransferase activity 0.8097432521395419 1.1655850178297382 0.2437822681858401 1.0 0.569244162310235 2 P23786 1 +Ether hydrolase activity 0.7188650919211774 1.1434586017806518 0.2528482334821409 1.0 0.5784861099364133 4 P07099 1 +Epoxide hydrolase activity 0.7188650919211774 1.1434586017806518 0.2528482334821409 1.0 0.5784861099364133 4 P07099 1 +Acetylgalactosaminyltransferase activity 0.8028308097432348 1.1365583189788224 0.2557229727866255 1.0 0.5798673896453332 2 Q10472 1 +Polypeptide n acetylgalactosaminyltransferase activity 0.8028308097432348 1.1365583189788224 0.2557229727866255 1.0 0.5798673896453332 2 Q10472 1 +Acetylglucosaminyltransferase activity 0.6051431500339374 1.1358673311725596 0.256012092558646 1.0 0.5798673896453332 5 O43505,P06865 2 +Peptidase activity 0.3266025200529577 1.1140632015055183 0.2652520739168373 1.0 0.5958306916578214 111 O43464,Q7Z2K6,Q99538,Q96E52,Q9UIQ6,Q10713,O14773,Q969V3,Q92820,P49721,P67812,O75844,Q99797,Q15005,Q4J6C6,Q96K76,Q9HB40,P28070,P09960,P42892,P10619,Q9NZ08,Q5JRX3,Q8TCT8,Q92542,P28072,Q92643,Q9BT78,Q16740,Q9BXS4,Q96FW1,Q9HBH5,Q9UJ14,P55786,Q9H3G5,Q8TCT9 36 +Dolichyl phosphate mannose protein mannosyltransferase activity 0.7955892034232966 1.1062319710167392 0.2686261281500017 1.0 0.599446483014536 2 Q6ZXV5 1 +3 phosphoadenosine 5 phosphosulfate binding 0.7949308755760376 1.1034795681323155 0.2698189596440175 1.0 0.6001374241509325 2 Q9NRB3 1 +Threonine type peptidase activity 0.4966032291224332 1.0902346463620305 0.2756097951997966 1.0 0.6090304254902824 10 Q9UJ14,P28070,P49721 3 +Potassium ion transmembrane transporter activity 0.790322580645162 1.084235345461524 0.278260463768087 1.0 0.6128946033400814 2 P05023 1 +Mhc class i protein binding 0.5369948309974284 1.0658582096472164 0.286487742639284 1.0 0.6229389475948591 8 Q9BUN8,Q03518,P51572 3 +Iron ion binding 0.3787746221884868 1.0640087904931292 0.2873247173741493 1.0 0.6237608481013881 26 Q16850,Q15800,Q9NVH6,Q9BU89,Q6UW02,P13674 6 +Phosphatidylglycerol binding 0.7837393021724828 1.056816428745072 0.2905953749522256 1.0 0.6266970059208589 2 O60313 1 +Cardiolipin binding 0.7837393021724828 1.056816428745072 0.2905953749522256 1.0 0.6266970059208589 2 O60313 1 +Cysteine type endopeptidase regulator activity involved in apoptotic process 0.5530353063248252 1.0559677775855247 0.2909829365239602 1.0 0.6266970059208589 6 Q9BXK5,P51812 2 +Galactosyltransferase activity 0.5849188746377849 1.041279279121459 0.2977459506058544 1.0 0.6302753066563179 5 O43505,Q96L58 2 +Ubiquinone binding 0.7755102040816336 1.022675164852215 0.3064614575327533 1.0 0.6420538426775697 2 P21912 1 +O acetyltransferase activity 0.7745227123107317 1.0185888465666568 0.3083982015487192 1.0 0.6420538426775697 2 Q8NF37 1 +P type calcium transporter activity 0.7872900889035173 1.01551073310733 0.3098624328848596 1.0 0.6420538426775697 3 P16615,P98194 2 +Transmembrane transporter binding 0.3642191605176137 1.0150161538888711 0.3100981272859233 1.0 0.6420538426775697 31 P0DP25,P21796,Q9HD47 3 +Trna methyltransferase activity 0.5303352298654831 1.009813337777058 0.3125847287534335 1.0 0.642666635969616 7 Q9UBP6 1 +High density lipoprotein particle binding 0.7848609930652358 1.0061480646926106 0.3143443506479384 1.0 0.6433644164616692 3 Q9BQE5 1 +Transferase activity transferring sulphur containing groups 0.4807396832371746 0.9963616108130972 0.3190744783695334 1.0 0.6501082700212832 10 Q9NRB3,Q8NCH0,Q7LGA3,Q5VV42 4 +Sulfuric ester hydrolase activity 0.7679394338380237 0.9914092190629212 0.3214858004245087 1.0 0.6540407227199212 2 P15586 1 +5 3 dna helicase activity 0.573700985722386 0.988945932269652 0.3226895958014366 1.0 0.6545300905882872 5 P51530,Q96RR1 2 +Trna guanine methyltransferase activity 0.5377363134046926 0.9793736399139912 0.3273953967754726 1.0 0.6601340418662719 6 Q9UBP6 1 +Glutamate receptor binding 0.5365460102322549 0.97342209692567 0.3303435610342395 1.0 0.6641078394164668 6 P0DP25 1 +Solute proton antiporter activity 0.7623436471362748 0.9683970305289538 0.3328461219245333 1.0 0.6652027642580012 2 O95202 1 +C palmitoyltransferase activity 0.761026991441739 0.9629951902033984 0.3355499370176551 1.0 0.6686398305087877 2 O15269 1 +Phosphoric diester hydrolase activity 0.5158180302860228 0.9542995036259216 0.3399320592339487 1.0 0.6723697790983234 8 P09601 1 +Mirna binding 0.4215423481099504 0.9498603070355424 0.3421832378522851 1.0 0.6740543047861296 14 P67809,P98175,Q9BWF3,Q14671,Q06787,P22626 6 +Threonine type endopeptidase activity 0.5134475574253535 0.9418221015027792 0.3462837276836008 1.0 0.6761849712609762 8 P28070,P49721 2 +Endopeptidase activator activity 0.6676872130848188 0.9306565063006376 0.3520312748409391 1.0 0.6817451633906205 4 P61289 1 +Volume sensitive anion channel activity 0.7625946657885923 0.9208428745195212 0.357132466882855 1.0 0.6817451633906205 3 Q9C0H2,Q8TDW0 2 +Tap binding 0.6646902868037826 0.9183143743495816 0.3584543039567804 1.0 0.6817451633906205 4 P04439,Q03518 2 +Nucleotidase activity 0.5252878891918065 0.9172148102011108 0.3590300875406222 1.0 0.6817451633906205 6 Q969T7,Q9H857 2 +Peptidyl proline 4 dioxygenase activity 0.7616068488640019 0.9170827055535644 0.3590993028531981 1.0 0.6817451633906205 3 P07237,P13674 2 +Procollagen proline 4 dioxygenase activity 0.7616068488640019 0.9170827055535644 0.3590993028531981 1.0 0.6817451633906205 3 P07237,P13674 2 +Myosin binding 0.4656529229122957 0.9070740452264432 0.3643676422880719 1.0 0.6817451633906205 10 Q9HBM0,Q15907 2 +Myosin v binding 0.6576239543571932 0.889288113296964 0.3738482581455615 1.0 0.6907101264945614 4 Q15907 1 +Heparin binding 0.4454033946523807 0.8715523243812743 0.3834526491486716 1.0 0.6985417562909447 11 O14737,P05067 2 +Protein phosphatase 2a binding 0.4787960116935866 0.8627856294662173 0.3882553416989576 1.0 0.7046123473141306 9 P04637,P42224,P18031,Q86XL3,P78318 5 +Steroid dehydrogenase activity 0.5007316550053584 0.8567901484162328 0.3915608712143807 1.0 0.7046123473141306 7 Q3SXM5,Q53GQ0,Q9HBH5 3 +Channel regulator activity 0.384126082203678 0.8451673318553213 0.3980174191377339 1.0 0.7086928736223813 18 Q9HD47,Q9UEU0,Q9P246,P62942,O15400 5 +Fatty acid synthase activity 0.7314022383146664 0.8429492735141532 0.3992568144029624 1.0 0.7086928736223813 2 Q8IVS2 1 +Sphingolipid transporter activity 0.7307439104674138 0.8403182465829174 0.4007299734526168 1.0 0.7086928736223813 2 P48739 1 +Phosphatidylcholine transporter activity 0.7307439104674138 0.8403182465829174 0.4007299734526168 1.0 0.7086928736223813 2 P48739 1 +Alcohol dehydrogenase nadpplus activity 0.4965477339318395 0.8352675399428667 0.4035670894057133 1.0 0.7086928736223813 7 Q9HBH5,Q8NBN7 2 +Antigen binding 0.4960817411755813 0.8328727144940192 0.4049165196104605 1.0 0.7086928736223813 7 P04439,Q03518,Q15392 3 +Pre mrna intronic binding 0.5393244377933126 0.8298236678279715 0.4066384872156168 1.0 0.7091388204201643 5 P22626 1 +Phosphotransferase activity for other substituted phosphate groups 0.5073782362148546 0.8282427235069311 0.4075330527948111 1.0 0.7091388204201643 6 Q5H8A4,Q9NRN7,O14735 3 +Intraciliary transport particle b binding 0.72712310730744 0.825879727951058 0.4088723212765899 1.0 0.709786578452892 2 Q92845 1 +Peptide transmembrane transporter activity 0.7264647794601461 0.8232604858185173 0.4103598789635188 1.0 0.709786578452892 2 Q03518 1 +Azole transmembrane transporter activity 0.7264647794601405 0.8232604858184943 0.4103598789635319 1.0 0.709786578452892 2 Q9HC21 1 +Flavin adenine dinucleotide binding 0.348474679572005 0.8099720054350619 0.4179562654601185 1.0 0.7157644791157544 27 Q14534,O15254,O00116,Q16134,P16435,P00387,Q15067,Q8NB78,Q15392,Q96HE7,A1L0T0 11 +Ubiquitin like protein conjugating enzyme binding 0.4053396764787065 0.8060814611970123 0.420195880250215 1.0 0.7157644791157544 13 Q92564 1 +Voltage gated chloride channel activity 0.7215273206056627 0.8036763394708082 0.4215839221606341 1.0 0.7157644791157544 2 P51790 1 +Aromatic amino acid transmembrane transporter activity 0.7208689927583948 0.8010733152210281 0.4230892034847762 1.0 0.7157644791157544 2 Q8N697 1 +Cation cation antiporter activity 0.7208689927583904 0.801073315221009 0.4230892034847873 1.0 0.7157644791157544 2 O95202 1 +Calcium cation antiporter activity 0.7208689927583904 0.801073315221009 0.4230892034847873 1.0 0.7157644791157544 2 O95202 1 +Neurexin family protein binding 0.729667434968705 0.7969032346521668 0.4255072321578264 1.0 0.7173545676470251 3 O00560,P16870 2 +Nedd8 specific protease activity 0.7270332565031221 0.7871302661708028 0.4312056134684749 1.0 0.7234671959304413 3 Q9BT78,Q96FW1 2 +Oxidoreductase activity acting on the ch nh2 group of donors 0.7259479178956552 0.7831105660738159 0.4335621869569011 1.0 0.7238464521798876 3 Q9NVS9 1 +Thiolester hydrolase activity 0.3914652573415378 0.7764472339325581 0.4374849648018486 1.0 0.7241681695075667 15 P50897,Q9UMR5 2 +Hormone binding 0.4962427372072614 0.7733191589036559 0.4393335199057757 1.0 0.7254608184106309 6 P42892 1 +Collagen binding 0.4803076197476109 0.7681589411538862 0.4423927633149689 1.0 0.7272032785286268 8 Q92791,O75718,Q53GQ0 3 +Phosphatidylinositol phosphate phosphatase activity 0.4948615939791186 0.7665335220385232 0.4433589136623128 1.0 0.7272032785286268 6 Q8WUK0,Q10713 2 +Solute cation antiporter activity 0.7211063549555425 0.7652302449702441 0.4441344526701689 1.0 0.7272032785286268 3 P51790,O95202 2 +Sodium ion transmembrane transporter activity 0.7211063549555428 0.7652302449702433 0.4441344526701694 1.0 0.7272032785286268 3 P05023,P55011 2 +Structural constituent of eye lens 0.71452090879156 0.7410493783767096 0.4586635013013547 1.0 0.7320518591851645 3 P08670,Q99797 2 +Glycerophospholipid flippase activity 0.7053982883475982 0.7404979371340478 0.4589979124191607 1.0 0.7320518591851645 2 P08183 1 +Floppase activity 0.7053982883475982 0.7404979371340478 0.4589979124191607 1.0 0.7320518591851645 2 P08183 1 +Flippase activity 0.7053982883475982 0.7404979371340478 0.4589979124191607 1.0 0.7320518591851645 2 P08183 1 +Phosphatidylethanolamine flippase activity 0.7053982883475982 0.7404979371340478 0.4589979124191607 1.0 0.7320518591851645 2 P08183 1 +Atpase coupled intramembrane lipid transporter activity 0.7053982883475982 0.7404979371340478 0.4589979124191607 1.0 0.7320518591851645 2 P08183 1 +Metalloexopeptidase activity 0.3546681926316166 0.7173420506342342 0.4731630666634006 1.0 0.7503250963775513 22 P09960,Q9UIQ6,Q9NZ08,O75844,Q969V3 5 +Pyruvate dehydrogenase acetyl transferring kinase activity 0.6942067149440434 0.697455452084912 0.4855178089905698 1.0 0.7586211222202501 2 Q15118 1 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.3530615607470483 0.6778378012734633 0.4978745403675215 1.0 0.7732702861250992 21 Q9P0J0,O75306,P03886,O96000,O75438,O43676 6 +Glutathione peroxidase activity 0.4726410078848768 0.6583817873538759 0.5102928353602465 1.0 0.7817612271153157 6 O43708,Q99735 2 +Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.6911425749094469 0.6566671745660603 0.5113949454786724 1.0 0.7817612271153157 3 O00767,O95864 2 +Protein tyrosine kinase inhibitor activity 0.6787360105332366 0.6391784317497462 0.522706861442852 1.0 0.786456652180687 2 O95684 1 +Death domain binding 0.6787360105332227 0.6391784317496947 0.5227068614428856 1.0 0.786456652180687 2 Q07820 1 +Bh domain binding 0.6787360105332227 0.6391784317496947 0.5227068614428856 1.0 0.786456652180687 2 Q07820 1 +Bh3 domain binding 0.6787360105332227 0.6391784317496947 0.5227068614428856 1.0 0.786456652180687 2 Q07820 1 +Phospholipase a2 activity 0.6859737652675686 0.6383538057664995 0.5232433941280572 1.0 0.786456652180687 3 Q9NP80 1 +Calcium independent phospholipase a2 activity 0.6859737652675686 0.6383538057664995 0.5232433941280572 1.0 0.786456652180687 3 Q9NP80 1 +Leukotriene c4 synthase activity 0.6747860434496203 0.624547568090438 0.532268041061509 1.0 0.7953343038400359 2 Q99735 1 +Gpi anchor binding 0.6819229502798774 0.624097114135207 0.532563809046676 1.0 0.7953343038400359 3 Q92643,O43292 2 +Mannosidase activity 0.6804177116517414 0.6188215511576988 0.5360339231762024 1.0 0.7970132402587079 3 O00754 1 +Peptidase activator activity involved in apoptotic process 0.6789594995060771 0.6137224382173619 0.5393987583556674 1.0 0.7997924830546231 3 P53634,Q9BXK5 2 +S methyltransferase activity 0.6775196476295174 0.6086988994766183 0.5427240366282617 1.0 0.8010216981916671 3 Q6UX53 1 +Aldo keto reductase nadp activity 0.4471327201852484 0.5974006979396553 0.5502398878768793 1.0 0.8075334855558087 8 Q9HBH5,Q8NBN7 2 +Nadp binding 0.3555997088952627 0.5928511856810971 0.5532807488141436 1.0 0.8093733047022614 17 P00374,Q14739,P16435 3 +Protein arginine n methyltransferase activity 0.4827018121910962 0.5763670620783646 0.564367102927088 1.0 0.8172115273523152 5 Q6P2P2,O60678,Q99873,Q86X55 4 +Cis trans isomerase activity 0.3294860263417349 0.5694973706919167 0.5690186545555536 1.0 0.8200385488239632 24 Q9Y680,O43708,P62942,O95302 4 +Phospholipid binding 0.2705928984447172 0.5355395187500523 0.5922768382985053 1.0 0.8410702437279715 87 Q9UM22,Q96L92,P07602,Q8NCC3,Q9NZJ7,P45880,O60784,Q14108,O14773,Q9BWH2,P21796,P04083,O00560,P50897,Q8WTV0 15 +L aspartate transmembrane transporter activity 0.5658804847092179 0.5283288635453643 0.5972711016482584 1.0 0.8426773992987519 4 Q9H936,Q9UJS0 2 +Acidic amino acid transmembrane transporter activity 0.5658804847092179 0.5283288635453643 0.5972711016482584 1.0 0.8426773992987519 4 Q9H936,Q9UJS0 2 +Misfolded protein binding 0.3951825146392231 0.4975714129410138 0.6187861570296578 1.0 0.8589687307490346 10 Q9BUN8,P48723,P46379 3 +Oxidoreductase activity acting on a sulfur group of donors 0.3133594778723136 0.4951818096898223 0.6204717896680643 1.0 0.8595526627511716 26 P78417,Q9UHG3,P07237,Q96JJ7,Q96HE7,Q9H3N1 6 +Histone acetyltransferase binding 0.4375375709021177 0.4930613962909185 0.621969206476215 1.0 0.860176873232669 6 Q8IXJ6 1 +Nadph binding 0.4627129501225123 0.4913501394756158 0.6231788229870601 1.0 0.860176873232669 5 Q14739 1 +L serine transmembrane transporter activity 0.6362738643844648 0.4880896560617832 0.6254863375357651 1.0 0.8603602557804705 2 Q15758 1 +Serine transmembrane transporter activity 0.6362738643844648 0.4880896560617832 0.6254863375357651 1.0 0.8603602557804705 2 Q15758 1 +Protein phosphatase regulator activity 0.3358056796014043 0.4858039285759356 0.627106188650012 1.0 0.8611589035609803 18 P0DP25,Q01105,P30154,Q86XL3,P78318,Q9NY27 6 +Neutral amino acid transmembrane transporter activity 0.6364833717484324 0.4708834947523784 0.6377239352818838 1.0 0.8668956841951291 3 P08195,Q15758 2 +Metalloaminopeptidase activity 0.3667456602555634 0.4689756030045837 0.639087074753184 1.0 0.8676516829066705 12 Q9NZ08,P09960,Q9UIQ6 3 +G protein beta subunit binding 0.6351662825156266 0.4666516908373666 0.64074909804711 1.0 0.868173503734818 3 P48643,P63218 2 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides 0.3877529423442891 0.4560708247068759 0.648339049220561 1.0 0.8740999681455777 10 Q9NQE9,Q13510 2 +Translation initiation factor binding 0.3403683806467814 0.4535312594216521 0.6501662393877612 1.0 0.8741821839402588 16 P55010 1 +Apolipoprotein binding 0.6286412352901447 0.445883513760872 0.6556813916218922 1.0 0.8778429216074797 3 Q8WTV0 1 +Copper ion binding 0.4143600334500387 0.4347842611825544 0.6637190300653613 1.0 0.8851758212549813 8 O60888,Q9Y6N1 2 +Gdp binding 0.3125050539600393 0.4316155972914256 0.6660208204121063 1.0 0.8851798963801113 24 Q15907,P61225,P61026 3 +Cytokine activity 0.4238501733399623 0.4311937862306881 0.6663274716680307 1.0 0.8851798963801113 6 Q92520 1 +Nuclear export signal receptor activity 0.4132585751979029 0.4294683780914284 0.6675824016140401 1.0 0.8859809412045708 8 P62826,P35658,Q9C0E2,P55060,O15504,Q9UIA9,Q9HAV4 7 +Xenobiotic transmembrane transporter activity 0.6203490286466872 0.4199803782739805 0.6744997879237378 1.0 0.888222104446085 3 P08183,P11166 2 +Phosphatidylinositol bisphosphate phosphatase activity 0.4450177501824374 0.4189082758793028 0.6752831685500187 1.0 0.8883928616258232 5 Q10713 1 +Chaperone binding 0.2833152499765067 0.4094044436378626 0.682242879166375 1.0 0.8889435021928127 40 Q9HAV7,Q9BTW9,Q96KC8,P55011,P62072,O95433,Q14108,O43615,P05023,Q13217,P53634,O43808 12 +Abc type transporter activity 0.4174237849590971 0.402778966545613 0.687110835800238 1.0 0.8908161557436788 6 Q9HD20,Q03518,P28288,O75027 4 +Ephrin receptor binding 0.4373075841395529 0.3883152696273418 0.6977827386137669 1.0 0.8963012682193848 5 O00560 1 +Metal dependent deubiquitinase activity 0.40257171117705 0.3730413284353872 0.7091176848192138 1.0 0.906074549950354 7 Q6P2Q9,Q7L5N1,P51665,O00487,O15372,Q92905 6 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.3380796382978736 0.3677138167939909 0.7130866369937507 1.0 0.9073827150510368 13 Q14739,Q8N4Q0,Q15392 3 +Protein arginine omega n monomethyltransferase activity 0.6018539488639572 0.3643228437415503 0.715616943488842 1.0 0.9089003983190058 3 O60678 1 +Sodium channel regulator activity 0.518265319104178 0.3611078803106655 0.7180188025336747 1.0 0.909357110457716 4 Q9HD47 1 +Guanylate kinase activity 0.5182360384583797 0.3610112975865415 0.7180910015570796 1.0 0.909357110457716 4 Q14168 1 +N methyltransferase activity 0.3212041018855461 0.3517927366298308 0.7249937061463494 1.0 0.9156751362945064 17 Q15291,P61964,Q9UBL3,Q86X55,O14744,Q03164,Q99873,O96028,O75648,Q6UXN9,Q7Z4G4,Q7Z2T5,P22087,Q6P2P2,O60678,Q14166 16 +Cytokine receptor binding 0.3095932279831218 0.3453189997486163 0.7298545644546126 1.0 0.9179117810046769 21 Q9NZ08,P62942 2 +Class i dna apurinic or apyrimidinic site endonuclease activity 0.5872284397630037 0.3344826731809556 0.738015363542579 1.0 0.9204662240401154 2 P78549 1 +Chloride channel inhibitor activity 0.5084659720106757 0.3292768570124215 0.7419464350927318 1.0 0.9204662240401154 4 Q9UEU0 1 +Chloride channel regulator activity 0.5084659720106757 0.3292768570124215 0.7419464350927318 1.0 0.9204662240401154 4 Q9UEU0 1 +Ccr5 chemokine receptor binding 0.5849242922975614 0.3279272260663032 0.7429666875569754 1.0 0.9204662240401154 2 P42224 1 +Glucosidase activity 0.4215457613038209 0.3278691091112077 0.7430106311788127 1.0 0.9204662240401154 5 P04062 1 +Protein self association 0.341706099397589 0.3204550359627663 0.748623410637256 1.0 0.9225202658019916 12 Q9Y282,Q9BTV4,P11166,P53634,P28288 5 +Structural constituent of nuclear pore 0.308404906884422 0.3202990888225777 0.7487416138186878 1.0 0.9225202658019916 20 Q7Z3B4,Q8NFH5,Q9BTX1,Q9BW27,Q8N1F7 5 +Poly g binding 0.3972988444544288 0.3168490297305191 0.7513581590801137 1.0 0.922852513011208 6 O14979,Q96EP5 2 +Long chain fatty acid coa ligase activity 0.4145611416940481 0.3020679759129535 0.7626002443172535 1.0 0.930317533238014 5 P33121,O95573,Q9UKU0 3 +Arachidonate coa ligase activity 0.4145611416940481 0.3020679759129535 0.7626002443172535 1.0 0.930317533238014 5 P33121,O95573,Q9UKU0 3 +Ribosome binding 0.2724666957351894 0.3005278600050684 0.7637745487712377 1.0 0.9309144500270063 40 Q96A33,Q9UM00,P04844,Q7Z739,Q9NTK5,P46379,O95202,Q07021,P42345,Q06787,Q9UHB9,Q969V3,Q15070 13 +Microtubule minus end binding 0.4122438965671212 0.2936512725517314 0.7690243922624238 1.0 0.935475118750251 5 Q9H6D7 1 +Cysteine type endopeptidase inhibitor activity involved in apoptotic process 0.4961213311727117 0.2906536059243185 0.7713162574448447 1.0 0.936746017754731 4 P51812 1 +Calcium dependent protein binding 0.303905797430244 0.2885138902442832 0.7729533994788138 1.0 0.9370594735876075 20 O76024,Q8WUM4,P0DP25,P04083,P20073 5 +Protein disulfide isomerase activity 0.3413957964555281 0.2605523752677096 0.7944377203046304 1.0 0.9496067890726988 11 Q6ZRP7,P07237,Q96JJ7 3 +Coreceptor activity 0.5552995391705088 0.2496086079939673 0.802890041054916 1.0 0.9537828372321948 2 P05556 1 +Polynucleotide adenylyltransferase activity 0.5510204081632673 0.2392497243586572 0.8109119475287052 1.0 0.9582966096779768 2 Q9NVV4 1 +Protein methyltransferase activity 0.2923338967917369 0.2374200961166933 0.8123309009190798 1.0 0.9582966096779768 22 O60725 1 +Enzyme activator activity 0.2571328333003684 0.2322984671664898 0.8163062029044443 1.0 0.9588580361911982 98 O43169,Q9P035,P07602,P0DP25,Q9NZJ7,P17900,Q96P47,Q9BXK5,O14737,P10619,Q05655,Q5JRX3,P05067 13 +Rna strand annealing activity 0.3938449879533063 0.229541142534975 0.8184483470027275 1.0 0.9600028896536996 5 P51114,O00571,Q06787 3 +Atp dependent peptidase activity 0.3937397034596375 0.2291888849718012 0.8187221111910505 1.0 0.9600028896536996 5 Q16740,Q96TA2,O76031,Q9Y4W6 4 +Phosphatidylinositol 4 5 bisphosphate phosphatase activity 0.4713240182916012 0.2185276965785116 0.8270179809845839 1.0 0.9663950439880048 4 Q10713 1 +Cyclin dependent protein kinase activity 0.3721160184574832 0.2171229994328908 0.8281124905229469 1.0 0.9668426757909664 6 Q00534,P06493,P11802,P24941,P50750 5 +Single stranded dna 3 5 exodeoxyribonuclease activity 0.5398288347597121 0.2133436475774248 0.831058931271879 1.0 0.9673062854730724 2 Q9NVH0 1 +Protein arginine omega n asymmetric methyltransferase activity 0.54395785314454 0.2121150204102005 0.8320173017306136 1.0 0.9673062854730724 3 O60678,Q86X55 2 +Extracellular matrix structural constituent 0.5325872284397648 0.1975094055812257 0.8434289218223627 1.0 0.9725185183445096 2 P07942 1 +Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity 0.5356451301550961 0.1933494357729479 0.8466853125432929 1.0 0.9738378588178512 3 Q10713 1 +Phosphatidylinositol phosphate 5 phosphatase activity 0.5356451301550961 0.1933494357729479 0.8466853125432929 1.0 0.9738378588178512 3 Q10713 1 +Oxidoreductase activity acting on the ch ch group of donors 0.2741356467331885 0.1851299128162624 0.8531271400803169 1.0 0.9775714868205316 28 Q9NZ01,O15254,Q6NUM9,Q8N4Q0,Q15067,Q14739,Q15392,Q7KZN9 8 +Histone methyltransferase activity h3 k4 specific 0.378912685337728 0.1813645969513062 0.856081405559203 1.0 0.9779616674244436 5 Q6UXN9,P61964,Q9UBL3,Q03164 4 +Protein n terminus binding 0.2577935671983558 0.1680199178263172 0.8665676096735995 1.0 0.9824168895725082 43 Q8IZL8,Q99623,Q9UBU8,P40855,P60228,P0DP25,Q969G3,Q15067,Q9UJW0,O00560,O75381,Q13190 12 +3 hydroxyacyl coa dehydrogenase activity 0.3585794335721536 0.1677837774587783 0.8667533852814109 1.0 0.9824168895725082 6 Q16836 1 +Anaphase promoting complex binding 0.5111915734035569 0.1550611827896783 0.8767730836347476 1.0 0.9871869268099602 2 P53350 1 +Syntaxin binding 0.282593813206583 0.1450145757027573 0.884699363691269 1.0 0.9933573894565942 20 P49755,Q9P253,O43752,O15400 4 +1 acylglycerophosphocholine o acyltransferase activity 0.4357957971928782 0.1294575119268095 0.8969956425500041 1.0 1.0 4 Q8NF37,Q7L5N7 2 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 0.3572430655608 0.1182819907601419 0.9058442265124008 1.0 1.0 5 O15254 1 +Sequence specific mrna binding 0.3415270534092351 0.1168357272171074 0.9069902313991548 1.0 1.0 8 P00374,Q08211 2 +Regulatory rna binding 0.2804182509965846 0.0955676930582194 0.923863924926378 1.0 1.0 17 P67809,P98175,Q08211,Q9BWF3,Q14671,Q06787,P22626 7 +Histone arginine n methyltransferase activity 0.4823839315113499 0.0934467140039898 0.9255486804373688 1.0 1.0 3 Q99873,Q86X55 2 +Primary mirna binding 0.4667544437129712 0.0875020936722857 0.9302724213066214 1.0 1.0 2 P17844 1 +Nuclear receptor activity 0.4667544437129712 0.0875020936722857 0.9302724213066214 1.0 1.0 2 P24468 1 +Pentosyltransferase activity 0.2876606317914809 0.0827438773153497 0.9340551954188672 1.0 1.0 13 P43490,Q13126 2 +Ubiquitin protein transferase activator activity 0.4558920342330503 0.075031763281321 0.940189439670811 1.0 1.0 2 Q9Y679 1 +Sulfurtransferase activity 0.4695423114916028 0.0747024279518921 0.9404514758471708 1.0 1.0 3 O75648,P25325 2 +Acyl coa oxidase activity 0.4684868047122753 0.073252816832396 0.9416049374874158 1.0 1.0 3 O15254 1 +Carboxylic ester hydrolase activity 0.2557435557847204 0.0669742208989997 0.9466022258514748 1.0 1.0 33 Q8NCG7,Q15165,Q9NP80,Q9NUJ1,Q9BW92 5 +Carboxy lyase activity 0.2930064347727493 0.0650600164110879 0.9481262152344404 1.0 1.0 12 Q9UG56 1 +Structural constituent of muscle 0.33574958813839 0.064381608102975 0.9486663742489484 1.0 1.0 5 Q16527,Q12797,P60660,Q15149 4 +Phosphatase regulator activity 0.2678000296534735 0.0623040657769369 0.9503206907476844 1.0 1.0 21 Q86XL3,P0DP25 2 +Carbon carbon lyase activity 0.2741154797826827 0.0603625325975137 0.9518668988742364 1.0 1.0 17 O95470,Q9UG56 2 +Fatty acid binding 0.3067735895107652 0.0554685502089081 0.9557651846593088 1.0 1.0 10 Q13277,O15254 2 +Camp dependent protein kinase regulator activity 0.4461639776094641 0.0457503419550056 0.9635092387107842 1.0 1.0 3 P54619,P10644 2 +Histone lysine n methyltransferase activity 0.3202506596306103 0.0415682965046305 0.9668428471109805 1.0 1.0 8 Q15291,Q03164,Q9UBL3,P61964,O96028,Q6UXN9,Q14166 7 +Lysine n methyltransferase activity 0.3202506596306103 0.0415682965046305 0.9668428471109805 1.0 1.0 8 Q15291,Q03164,Q9UBL3,P61964,O96028,Q6UXN9,Q14166 7 +Insulin like growth factor receptor binding 0.3986175115207396 0.0314764190539954 0.9748895976936816 1.0 1.0 2 Q04917 1 +Glucocorticoid receptor binding 0.3982883475971056 0.0313176449031794 0.9750162187119268 1.0 1.0 2 Q04917 1 +Channel inhibitor activity 0.312390738148085 0.0272255899620932 0.9782798054302264 1.0 1.0 7 P62942 1 +Sumo ligase activity 0.382817643186309 0.0247891085482828 0.980223178509813 1.0 1.0 2 Q96MF7 1 +Protease binding 0.2613425635200836 0.0239438158413245 0.980897424302158 1.0 1.0 21 Q9BUN8,Q9NZJ7 2 +Rna polymerase ii ctd heptapeptide repeat kinase activity 0.3120263591433314 0.0154435813766375 0.9876782946544496 1.0 1.0 5 Q00534,P06493,P50750,P11802 4 +Lipase binding 0.322580645161293 0.0121609821635216 0.9902971792456474 1.0 1.0 2 Q96CS3 1 +G quadruplex rna binding 0.3057932850559606 0.0108755072020082 0.9913227717652122 1.0 1.0 2 Q06787 1 +Unmethylated cpg binding 0.303818301514157 0.0107608943052257 0.9914142142749004 1.0 1.0 2 Q03164 1 +Lys48 specific deubiquitinase activity 0.3629776021080411 0.0052480227804555 0.995812702869652 1.0 1.0 4 Q9H8M7,Q93009,O94966 3 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f4e0e06e3029a9ca1eb57e79c4383e1d7dfe3ed2 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "3 phosphoadenosine 5 phosphosulfate binding", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminoacyltransferase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bile acid binding", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chondroitin sulfotransferase activity", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione hydrolase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "Hypoglycin a gamma glutamyl transpeptidase activity", "I smad binding", "Icosanoid binding", "Identical protein binding", "Ige binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosamine synthase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreductase activity acting on the ch nh2 group of donors oxygen as acceptor", "Oxidoreduction driven active transmembrane transporter activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphate ion transmembrane transporter activity", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphatidylserine flippase activity", "Phosphatidylserine floppase activity", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine tyrosine kinase activity", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Store operated calcium channel activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toll like receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Wnt protein binding", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding"], "available_proteins": ["AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG8", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC5", "ANAPC7", "ANKFY1", "ANKHD1", "ANKLE2", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL8A", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATG13", "ATG16L1", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPIF1", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCCIP", "BCL2L13", "BCLAF1", "BCS1L", "BDH2", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRIX1", "BRPF1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf35", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCDC88A", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP4B", "CHMP5", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT4", "CNOT7", "CNOT9", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ5", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPE", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP2", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "EDC3", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP2", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERCC2", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FOXRED2", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLM", "GCN1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GIGYF2", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPKOW", "GPR107", "GPR89B", "GPRASP2", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFAP3", "KIFBP", "KIFC1", "KLC1", "KLC2", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3HYPDH", "LAMB1", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZIC", "M6PR", "MACF1", "MAD1L1", "MAGT1", "MAK16", "MAN1A2", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAPK1", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCH5", "MARCKS", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBIP", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED24", "MED25", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL14", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MIB1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL3", "MRPL37", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS14", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MYBBP1A", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NACC1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NKRF", "NKTR", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F2", "NRBP1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDSS1", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11A", "PEX14", "PEX16", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGU", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTF1", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC15A4", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC4A1AP", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNE2", "TAB1", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D10A", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TES", "TEX264", "TFAM", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM165", "TMEM192", "TMEM201", "TMEM43", "TMEM59", "TMEM70", "TMLHE", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSR1", "TSTA3", "TTC1", "TTC26", "TTC4", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", 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1.870431483654663 0.2292796295173983 1.6319541950693098e-05 1.0 1.0 0.001485709034831 5.489393781591606e-05 +Horizontal nystagmus 7 23 2.428042000248285 0.0151805851620276 6.274271844660194 23.053398058252423 1.1086320165192889 0.2915732095622053 2.6115907074401723 2.1860242554539786 1.3408731048130669 0.3129960018850027 0.0157915832911141 0.2295798469686227 0.0949012099695084 0.0413751204339429 0.0042820394936164 +Laryngomalacia 3 11 2.41914656032434 0.015556970763966 3.6723300970873782 13.71116504854369 0.5978398108837641 0.454570785907933 2.014971007950381 1.945013939586594 0.9121070716381354 0.3097177989827632 0.1993291294447464 1.0 0.4461675288226883 0.1835520270988697 0.3451855796466592 +Ascites 12 27 2.4105818274247257 0.0159270981016799 6.538834951456311 25.800970873786408 0.2860997134153194 0.2561597752608451 2.6559964399945706 3.331112387328855 1.6846905274497244 0.2824645045304154 0.0175280828113989 1.0 0.1487873266068847 0.0931141624023252 0.0071993249598634 +Abnormal circulating cholesterol concentration 21 33 2.4092031810221237 0.0159873946895505 9.691747572815531 31.70873786407767 0.976903841313624 0.2790879029908041 4.4525142732793395 3.04459115485426 1.5883623188049951 0.3063455707490317 0.0230322868891505 1.0 1.0 0.0095088070763824 0.0032642482875436 +Abnormality of the larynx 10 41 2.398943585308121 0.016442447694897 10.682038834951456 46.699029126213595 0.7426785971038559 0.4816723930500222 4.067795342682343 4.403407664230521 0.9382180075001202 0.3633154044529258 0.0543513831656935 0.5123592328378659 0.0540831694948363 0.0682104000582474 0.1063137228069698 +Blindness 24 74 2.390125487740226 0.0168426169485298 17.50485436893204 77.9878640776699 0.5531690923808372 0.4517712920686044 6.330499123572238 7.312865926515748 1.2869313794328858 0.374312554297374 0.0014517684029004 0.2479618444070664 0.1246977476538018 0.0032939370021869 0.000675905901946 +Abnormal lower motor neuron morphology 2 7 2.379998714440955 0.0173126984492228 2.1771844660194173 8.701456310679612 0.8468629004048428 0.2893246976958152 1.3759952567341256 1.207057649999096 1.1584035743641086 0.2695692447215745 0.0669068976288491 1.0 0.2147385524083838 0.1219531221716571 0.1194171261960574 +Dysostosis multiplex 6 8 2.353021223169328 0.0186215712202508 3.983009708737864 7.990291262135922 0.4150973501220912 0.1595724105588133 1.65382835361071 1.246316090990369 1.8479195153421644 0.2123242141003258 0.0009332110294809 1.0 0.1837383274168749 0.090818300458346 0.0028394369313259 +Abnormally lax or hyperextensible skin 12 44 2.347844342759717 0.0188824105133553 10.3373786407767 42.60679611650485 0.3474462280446399 0.5687204029624341 3.951804420390705 4.299554326326563 0.9473596696641492 0.3538650259671493 0.0029070915041665 0.4570575797650001 0.1209939299005533 0.0034907253987009 0.0082058503706901 +Periventricular white matter hyperintensities 3 7 2.3297021999984686 0.0198218961948568 2.978155339805826 8.604368932038835 0.7206271937008832 0.2495118997135797 1.313488091366194 1.3113693798075805 1.4898193087366574 0.2872267653893681 0.0019802696370409 1.0 1.0 0.0051503840765812 0.0049176108076387 +Abnormal larynx morphology 7 23 2.3202425423700954 0.0203277604080096 6.839805825242719 27.718446601941743 0.5738284857128313 0.4761706892213789 2.8749956456134265 3.1319446353032743 0.987106786856402 0.3377886307734372 0.0453902200906583 0.3985608327989486 0.0801526286479979 0.0420396019683425 0.1385934634631117 +Splenomegaly 23 85 2.3179507293395107 0.0204519989572911 20.660194174757283 86.74029126213593 0.5649049994066069 0.3835571498509289 6.419862077062851 7.868335701486235 1.546158503499524 0.3590721878602594 0.0001788705496596 1.0 0.1820864285977347 0.0040878244038074 0.0001445432079647 +Muscle stiffness 4 17 2.3101032928769003 0.0208824361886921 5.109223300970874 19.216019417475728 1.2530133657268057 0.2695837776665858 2.5817154639007844 2.4582801786037667 1.0397164239726309 0.2961148999712332 0.0562549969103877 0.2333020504203794 0.4129317333780675 0.0438041643494559 0.1280001064666262 +Ventricular preexcitation 4 6 2.3095737359846944 0.0209117650576924 2.5145631067961167 6.497572815533981 0.9841118497305948 0.2225227126053997 1.468861772329754 1.5757549992030588 1.3097679632537274 0.2453287763295943 0.033250781651387 0.0036723611473879 0.014058804472369 0.0102137155300364 0.0017585862412997 +Elevated pulmonary artery pressure 9 25 2.30926143198921 0.0209290784605689 7.422330097087379 24.033980582524272 0.8771466934674594 0.3206437689207037 3.083196929894625 3.78086786662344 1.283632173810104 0.3146045769490745 0.0063878891312437 1.0 0.5782406044087871 0.0646269414847783 0.0109585410192187 +Macular degeneration 3 11 2.305045449378612 0.0211640281291873 3.5072815533980584 13.201456310679612 0.7081764422831481 0.3007939344006393 1.5711122114355351 1.3240485924903622 1.388921785741595 0.3097317018961461 0.1331835459157892 0.2220822570468345 0.0135419734012732 0.0367529115341812 0.2458770605062358 +Schizophrenia 6 18 2.271431322876005 0.0231208800357387 5.444174757281553 19.50242718446602 0.9817145874838714 0.3473822480141803 2.400301366302062 2.641618717487706 1.084663392230114 0.3211478296747099 0.0007788395103165 0.1795501084992132 0.0588586045542952 0.016869226769582 0.0032909138457879 +Abnormal lung lobation 2 13 2.2701263225336765 0.0231999196595178 3.266990291262136 13.402912621359222 0.8057824047211188 0.4237226990881645 1.8647412350490211 1.7258152040640289 0.8098324555644494 0.3032019531807652 0.1277836657156577 0.1471951297158956 0.0398064357050217 0.0449350347407693 0.2151867556135544 +Abnormal chorioretinal morphology 12 24 2.26648569422136 0.0234216620759248 8.45631067961165 26.4004854368932 0.7945769566543296 0.4616483000942599 3.6317817687878136 4.493501214243663 0.9878512993647718 0.3399479614013815 0.2502332948228845 1.0 0.6629984443692342 0.5126853547866922 0.3031335834316054 +Chronic fatigue 2 5 2.2641534056476007 0.0235646812258893 2.0800970873786406 7.354368932038835 0.6505903571445167 0.3551914870642563 1.248646642239502 1.3902068505046723 1.081635717396615 0.2816956203568134 0.033250781651387 1.0 1.0 0.3727200206787977 0.0621142898948071 +Abnormality of prothrombin 6 12 2.261122424340729 0.0237516771399719 4.5 13.25242718446602 0.3265563085399564 0.5312916537639599 2.2071155890213294 1.527854302271569 0.8954775795358557 0.3100216206843308 0.0201719243202223 1.0 1.0 0.0294507732567689 0.0448872219881859 +Supernumerary tooth 0 6 2.2607242992240635 0.0237763348040953 1.837378640776699 7.182038834951456 0.7585871881827633 0.400000437027925 1.4747917155327317 1.1734803097311852 0.8707169959243988 0.2908701317755205 0.6739723098236088 0.1305522111527444 0.2445730022705269 0.5094216597603356 0.7650208428589309 +Abnormal vascular physiology 14 52 2.259568560309364 0.0238480407093921 12.74757281553398 50.021844660194176 0.816183607478715 0.4136638745601454 4.907827009322534 5.622165606934028 1.2216480011219424 0.371091913776798 0.0022191616025776 1.0 0.4948207332297397 0.0240414238216899 0.0095879527582839 +Abnormal retinal vascular morphology 19 47 2.253482178823872 0.0242287631481386 11.550970873786408 50.40291262135922 0.374132464893944 0.4137648703700375 4.646725961814426 4.349733979382428 1.4638612584769457 0.3720428539009304 0.0059247754248939 0.5287686777468734 0.0620226994518361 0.0013547133277957 0.0084353301274375 +Hypocholesterolemia 6 9 2.250737397368896 0.0244021746531815 3.2645631067961167 8.048543689320388 1.205673434171466 0.2055905154190861 1.747510449264718 1.0646904903887575 1.232151298114248 0.2464368010987078 0.0011015965796577 1.0 1.0 0.003355333516566 0.0002481332774246 +Scotoma 8 14 2.250224077349972 0.0244347246212159 4.189320388349515 12.196601941747574 1.1271039056750725 0.2779036999445621 2.1128553643245884 2.0698220238662226 1.1901076059375446 0.2884356618441315 0.016772023035254 0.1755724648168266 0.0563311776114605 0.0155108289838298 0.0005743066382168 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2.232605234648426 0.025574988604802 2.162621359223301 6.968446601941747 0.7521093084296674 0.2992197670299059 1.410866607722538 1.225329167014724 1.1887948503174883 0.2730524920497975 0.0019802696370409 0.0697581245313758 0.0088504827764808 0.000371706641515 0.0049176108076387 +Abnormal macular morphology 4 23 2.225865740744102 0.0260231757332447 5.881067961165049 26.936893203883496 0.2429090782086877 0.4668963917414836 3.102290232183583 2.9305717090684964 1.1278643921545293 0.335754410396833 0.3888448431568223 0.4072806445693771 0.0855550276988868 0.1213880889040297 0.6091546028398355 +Segmental peripheral demyelination remyelination 1 5 2.208458950294626 0.0272122963246701 1.6601941747572817 4.737864077669903 1.1231406516527276 0.2457358043386077 1.1021021225411718 1.375663406058269 1.1869683790120098 0.2709829643602553 0.0734387458229045 0.0561990347849709 0.1094892401774078 0.0328731354880699 0.1129571724371578 +Decreased activity of mitochondrial complex i 7 35 2.206146706754166 0.0273737293226465 9.281553398058252 33.63834951456311 0.9162605947168436 0.3572379048008119 4.7041965890170365 4.116953486956332 1.2998989973013628 0.34388058367185 0.0005990417392704 1.0 0.0014189260290535 0.0002096397492041 0.0001428469927823 +Microdontia 7 26 2.188663986379411 0.0286212713800422 6.79126213592233 26.62135922330097 0.2926835447863038 0.6221511471419694 3.1882858040298023 3.2705407790552736 0.7151842473532629 0.2936653766443033 0.0594328113003231 1.0 0.058599533767272 0.0723391847179421 0.0785350950567567 +Supranuclear gaze palsy 7 18 2.1841754059358136 0.0289493614086677 5.186893203883495 19.1626213592233 0.8242716574954257 0.3183493558985887 2.2612229396433574 2.139608194404574 1.2188387108542005 0.2935859783151378 0.0032028710832211 1.0 1.0 0.0678108138951911 0.002448268499096 +Clumsiness 11 20 2.182854536404889 0.0290465239870092 6.75 20.57766990291262 0.9027704056640264 0.2559090219975202 2.4698423753801175 2.2221930931993956 1.527926415027724 0.282470536898918 0.0369558881194607 1.0 0.3777229935777695 0.1151104414767163 0.0305407497227627 +Progressive visual loss 8 19 2.1618454200128308 0.0306300931860772 5.325242718446602 22.429611650485437 0.7316954387450431 0.34231947196034 2.467466703195611 2.985791083259841 1.255625436621734 0.3056268024259221 0.1481988963527668 0.0490886173861251 0.1588529428511447 0.1044322137967542 0.0267628454277298 +Neuronal loss in central nervous system 5 12 2.153697017544878 0.0312639401960652 4.087378640776699 12.526699029126211 0.982175765643533 0.2959736314179056 1.731247914675439 1.993135251988059 1.1236470294677874 0.2967990988512021 0.0007765366578398 1.0 1.0 0.0352396407582777 0.0028128505043211 +Episodic vomiting 3 10 2.145309248488648 0.0319281295362876 4.179611650485437 11.12378640776699 1.060494846441687 0.2663322982599159 1.9809215871966128 1.7630834730718608 1.1982900451883365 0.2840581402107739 0.0283800761341597 0.1389130578490434 0.0354914601129098 0.0063239101987386 0.0616223233666864 +Delusions 11 18 2.140948387066273 0.0322782004765274 5.912621359223301 18.439320388349515 1.0629964764413025 0.2985925736346436 2.390745896997379 2.2281751696560335 1.2165016471530676 0.297036724651636 0.0002832454885396 0.1553991536419083 0.0443091130960601 0.0097601039903573 0.000217728528826 +Abnormal pupillary function 1 5 2.1321823745044286 0.0329918568395417 1.7985436893203883 6.25 0.9459174425459445 0.2892194993230557 1.1928988171245156 1.7202745886032773 1.109204161812943 0.2732247962160634 0.3290746509604469 1.0 1.0 0.5329697587184232 0.4493239706483273 +Postural tremor 10 19 2.130667207524505 0.0331165684675283 5.194174757281553 17.851941747572816 1.214872214945056 0.2487017685351703 2.341305968762478 2.2981463861426747 1.2391489410765593 0.2821199379659175 0.0036503385113878 0.1755724648168266 0.3209553841799009 0.0720513532108381 0.0028457755604085 +Optic neuropathy 8 22 2.129669495295763 0.0331989091313431 6.834951456310679 22.009708737864077 0.7947386425872367 0.3403162177193031 3.144874354625535 3.3508299091739815 1.3090216253320466 0.3062511530983536 0.0020323862439369 0.2068720246529641 0.0775813155228076 0.005869339632186 0.0004353880265266 +Capillary hemangioma 2 7 2.128761132094597 0.0332740281779118 2.533980582524272 7.133495145631068 1.1471796350867234 0.2683759543048971 1.4112277515033682 1.3471092449900268 0.9767941621718578 0.2786452679412407 0.1277836657156577 0.1471951297158956 0.0398064357050217 0.0449350347407693 0.2151867556135544 +Abnormal epiphyseal ossification 12 17 2.122138670093258 0.0338260949028474 6.451456310679611 16.274271844660195 1.1227269321938518 0.3276999393402902 3.140724178369711 2.4155680760400804 1.043634905787503 0.3148370578580727 0.0012042412797456 1.0 1.0 0.0213813720021448 0.0011157102419642 +Mucosal telangiectasiae 3 7 2.111947100686527 0.0346909868267459 3.2354368932038833 9.689320388349516 0.8501086222195428 0.291727970426265 1.410916714116348 1.5996305775803197 1.2598794700933909 0.2907637890882055 0.0201719243202223 1.0 0.2372212797486779 0.0294507732567689 0.0448872219881859 +Arthritis 11 38 2.0982501841611514 0.0358830505893519 10.45631067961165 41.12864077669903 0.9299077951686036 0.3844403642845474 3.7326340917241647 4.351147052994631 1.200139433310656 0.3557501916131977 0.0025414871403244 1.0 0.0201115001422002 0.0046431581501936 0.0061151720352403 +Amyotrophic lateral sclerosis 5 16 2.0883524234273936 0.0367660557982376 4.453883495145631 16.203883495145632 1.0855969203541704 0.3037117925086244 2.3812188822255287 1.5445439412417563 1.0118111691913367 0.2917679915833991 0.2018407917163677 1.0 0.327507803675052 0.2616785322574622 0.0473239117869584 +Slow decrease in visual acuity 4 7 2.0869910355829955 0.0368889448848661 2.313106796116505 7.985436893203883 0.7332483742783148 0.3617245659278226 1.567733834853386 1.5547551717475598 1.083959755774155 0.2999488674407273 0.2440769780599642 0.1135912525516411 0.2147385524083838 0.1219531221716571 0.031065887399213 +Urinary glycosaminoglycan excretion 4 7 2.08433966738036 0.0371292815563113 2.9490291262135924 6.563106796116505 0.4749855796693131 0.2196485727407601 1.2846457065606351 0.9261036754709504 1.6390629541794843 0.2603486997442626 0.0019802696370409 1.0 1.0 0.307957256786686 0.0049176108076387 +Calcinosis 1 5 2.0828624764265142 0.037263760790819 1.5072815533980584 5.099514563106796 1.1513451038285936 0.2590169313384529 1.041584579038491 0.4030222683885372 0.953608514142629 0.2639318719258676 0.0526107764239753 1.0 0.0921025797166938 0.0231366382468947 0.0820486275159116 +Abnormality of the posterior pituitary 2 6 2.076509818425031 0.0378468239934777 2.2815533980582523 7.881067961165049 0.2255040348146946 0.4866970034165402 1.637944933864368 1.642260703628462 0.9273713139703104 0.281613365984196 0.3430575480785555 0.1430638950507344 0.266209970857853 0.544318157098314 0.465786591734874 +Lower limb spasticity 24 79 2.072902041036803 0.0381813970536586 17.24271844660194 80.34466019417475 0.5234592060757025 0.5553383930423336 6.384471482056576 8.884788223572686 0.9712236167697867 0.3629508150226985 0.0101127639549155 0.5911762082883738 0.2600689834684315 0.0349871560996629 0.0082469651426675 +Prolonged partial thromboplastin time 3 6 2.071065490328504 0.0383526762965196 1.825242718446602 5.691747572815534 0.379515534158049 0.4976114453394669 1.2281265586251189 0.8300367604264026 0.8890522985814493 0.2975135288749165 0.084681911188206 1.0 1.0 0.0382400085743442 0.129364196063302 +Myoclonus 17 89 2.069046525026921 0.0385417210352811 19.92718446601942 92.40291262135922 0.7794869182612147 0.4142145469430702 6.660238401732631 11.33633180094438 1.369340457412049 0.3858779422292388 0.0039335401555745 0.3495133154240509 0.2319671346160944 0.0037872521296203 0.0033216565258275 +Abnormality of extrapyramidal motor function 14 71 2.0680622547538245 0.0386341694374845 17.723300970873787 74.23058252427184 0.6611914449106878 0.5008095396366101 5.517064505158221 6.985611887807198 1.1554912414277594 0.3847143245763222 0.0111283514010951 0.6312378177493598 0.8646762583733004 0.0112054092519221 0.0419043615161848 +Perimembranous ventricular septal defect 1 6 2.064983867812752 0.0389245267206712 1.6529126213592231 6.150485436893204 0.1136132488195529 0.528834782138146 1.4872977588340992 0.8485709044534837 0.8988514048233129 0.289697535306089 0.0526107764239753 0.0470522829573702 0.0039135152062846 0.0231366382468947 0.0820486275159116 +Abnormal aortic arch morphology 1 7 2.0644636280239324 0.0389737790392463 2.679611650485437 11.155339805825244 0.2349410067825678 0.5879590594196238 2.0981433874803153 2.1889274828803034 0.764806880444086 0.2835565040634389 0.4505760926260682 0.1755724648168266 0.0563311776114605 0.2526409373615763 0.5862027736389052 +Abnormal enchondral ossification 18 27 2.063834813835163 0.039033381001881 8.825242718446601 28.097087378640776 0.9354465670440578 0.4238671948965085 3.7994051258084856 4.343870948544361 0.9586864854575652 0.3408490652683477 0.0051015169602562 1.0 0.5657328567415809 0.0178492752405101 0.002896721501077 +Abnormality of the vasculature of the eye 16 68 2.062431856284836 0.0391666390098537 16.27912621359223 72.06553398058253 0.403343228775578 0.4479390001832676 5.629952078086087 5.671259209870798 1.3806507490937323 0.3789287537753926 0.0059402997283222 0.6707070078118527 0.0684371575145979 0.0013004985979235 0.0154317918224192 +Abnormal larynx physiology 4 14 2.0580373569476547 0.0395865475088965 3.7694174757281553 14.78640776699029 0.7777362681295714 0.3936810823701626 2.010346212391085 1.51625807571557 0.9784109402665334 0.3028779878197117 0.1543312662059056 1.0 0.0466281418945222 0.2166326226637888 0.0957448321565225 +Abnormal light and dark adapted electroretinogram 3 7 2.0555405666861395 0.039826821610166 1.7985436893203883 7.135922330097087 0.8897551200199579 0.2742817695009352 1.2050451450005106 0.7670210145007976 1.1859557261264115 0.267107203595487 0.1740597032129271 0.0040679264544396 0.0155240337321844 0.0834574734746242 0.0705348016344186 +Abnormal full field electroretinogram 3 7 2.0555405666861395 0.039826821610166 1.7985436893203883 7.135922330097087 0.8897551200199579 0.2742817695009352 1.2050451450005106 0.7670210145007976 1.1859557261264115 0.267107203595487 0.2299033716281589 0.0058373227860703 0.0219975904219434 0.1139407547181512 0.1088149775417643 +Metatarsus adductus 6 13 2.052069705519996 0.040162888598787 3.7694174757281553 13.25 0.9957104022100554 0.3572272245833284 1.816252583500775 2.104808410901558 0.7948300017734555 0.2882447196496276 0.1277836657156577 1.0 1.0 0.1899587232036964 0.0205229364106292 +Cutis laxa 9 33 2.049512685816397 0.0404120086559622 7.786407766990291 30.567961165048544 0.1942452097651432 0.5993697737339392 3.4525929061320935 3.496564571735676 0.8896354286885394 0.3267193204344998 0.0073749901855038 1.0 0.2178091494673695 0.0064725887331866 0.0127124954693858 +Arthralgia 7 30 2.0445718552297127 0.0408970866036104 8.067961165048544 33.66019417475728 0.4973169065736986 0.5336317295986659 3.339269543758109 3.852381429809718 0.8994568503620952 0.3283969638661596 0.0337722078104907 1.0 0.2462273560384733 0.0329244460205432 0.1085370543162667 +Occipital encephalocele 2 6 2.0346777673325125 0.0418833066761645 1.7815533980582523 4.604368932038835 0.8913531306831002 0.3449248300543996 1.1259729404753154 1.0799498099654865 0.9443723387633002 0.2912629460783046 0.0878170005060168 1.0 1.0 1.0 0.1533018949933901 +Abnormality of the distal phalanges of the toes 2 6 2.031612655521695 0.0421928844893324 2.094660194174758 5.058252427184466 1.0467054837889296 0.2409661092181722 1.19191069217632 0.9786581135773657 1.170071232541671 0.254087308422285 0.0174514302411212 1.0 0.0088504827764808 0.0051503840765812 0.0336357980244025 +External ophthalmoplegia 7 17 2.028055632031727 0.0425545704569125 5.0 17.00242718446602 0.5663831977441792 0.4827064568652057 2.377074975025652 3.293490775365303 0.8939003315322738 0.3080856115403083 0.5243863237407251 1.0 1.0 0.3067990234802971 0.0230912453221162 +Atrophy degeneration involving the corticospinal tracts 3 12 2.025734157667467 0.0427920343665715 3.046116504854369 12.830097087378642 0.5862844965366169 0.5076242219583529 1.6751494545754666 1.7194679099903734 0.8501612708621024 0.329209288406221 0.0499895629934735 0.1635258499471353 0.048990890514732 0.0596874537258691 0.1034478004905659 +Dolichocephaly 12 28 2.0215660619168614 0.0432212011261641 8.254854368932039 32.99271844660194 0.3115867009615017 0.6117064857723883 3.190641766432611 7.582071686330195 0.7651955171401985 0.305025362921914 0.8251488813755664 1.0 1.0 0.708778021079272 0.7442663391664649 +Turricephaly 3 9 2.021074543961073 0.0432720490486757 3.087378640776699 9.771844660194176 0.3778544149344532 0.5461672749854712 1.9401571156301212 1.76023594379029 0.8273403907237378 0.3112615571463046 0.0314966989465631 1.0 0.266209970857853 0.181169408752189 0.0678374957909117 +Sclerocornea 7 9 2.019621457269904 0.0434226677101787 3.1237864077669903 9.691747572815531 0.6327344825269637 0.4627390478210677 1.6813417067808916 1.93451779053892 0.8687114450254205 0.3021244352075571 0.1452955045169016 1.0 1.0 0.2076979954646016 0.0259406914165302 +Impaired vibration sensation in the lower limbs 1 13 2.0122177598581 0.0441969871611065 3.5436893203883497 13.5752427184466 0.6952737045250533 0.4242336391370475 2.2993316843683766 2.2069327415111175 1.0005780794846004 0.3215228956981494 0.4376506131270111 0.1715759324473242 0.0538434207197609 0.2436114581565515 0.5723021179426622 +Mania 6 12 2.0109622892931105 0.0443294400951319 4.29126213592233 13.815533980582524 0.5633198814967983 0.4160552944360035 2.179476502394243 2.2801276272213657 1.0919629859527038 0.3085705503430486 0.0057118459116528 1.0 0.2590666885683055 0.0063239101987386 0.0159032502878613 +Lacticaciduria 2 5 2.007417987815513 0.0447051750943574 1.674757281553398 4.849514563106796 0.7129753583310345 0.3234768766519366 1.205184467740076 1.4436586333991552 1.2463576287305282 0.29112130721695 0.0174514302411212 0.0697581245313758 0.1349531130589082 0.0498779046475234 0.0336357980244025 +Abnormal choroid morphology 12 25 2.003516887401996 0.0451218368235162 8.601941747572816 27.3495145631068 0.7703870977149745 0.4720542672282273 3.667860427157979 4.9083023341259215 0.9853391072008848 0.3404582870775928 0.3494492465656084 1.0 0.7089494965911767 0.5980906067333986 0.4231007853550139 +Abnormality of the alveolar ridges 2 7 2.002947404458943 0.0451829341436278 2.1092233009708736 6.368932038834951 1.3424122348723253 0.2105791674194365 1.182482323454481 1.3741037061958896 0.9200079991465796 0.2386077675723682 0.0953282016037405 1.0 1.0 0.0322769586697076 0.1652047572335966 +Undetectable electroretinogram 2 5 2.002063627124382 0.0452778888233156 1.7427184466019416 4.415048543689321 1.0664751707047182 0.1916317897201908 0.9612998826677368 0.7632752290710167 1.383034454070232 0.2429274936147374 0.0116013363164454 0.0607401038440192 0.1180585699575878 0.0382400085743442 0.0227185425065092 +Primary adrenal insufficiency 7 13 1.993520987505259 0.0462044277122606 4.735436893203883 14.053398058252426 0.4481201134263297 0.4664055341667871 2.4306710395132063 2.5622470240832387 1.0298993153674545 0.3194227062256599 0.0682588372375845 1.0 1.0 0.2616785322574622 0.1368997099058324 +Hydrocephalus 20 71 1.9785546558266465 0.0478661691898083 17.5 74.83009708737865 0.4864280032519437 0.6085787069163106 5.8879092832817435 9.478912056611868 0.8088784016382273 0.3500416531762792 0.2716171191696188 1.0 0.7590193117736533 0.3754608214358252 0.2980792949746005 +Pulmonary infiltrates 3 7 1.97743258867346 0.047992753345698 2.203883495145631 7.41747572815534 0.5937593446740285 0.3342650103364393 1.20966354385806 1.2445943063002318 1.1896790379366604 0.2811562889912624 0.01562494729998 1.0 0.0255840399150975 0.0033024410276518 0.0353483729682259 +Peripheral demyelination 3 17 1.976425976471272 0.0481065518971188 4.524271844660194 16.973300970873787 0.9472740181618832 0.3208012027704231 2.3341893675900383 2.269845761985369 1.1784704386991718 0.3026863353342601 0.0542703985223047 0.1675604235637086 0.3076603852203092 0.063688713570506 0.1114244714574529 +Mitochondrial respiratory chain defects 3 6 1.970112578579437 0.0488254696328021 1.8033980582524272 5.177184466019417 1.0048180638921334 0.285673153216041 1.1353491002390874 1.0681459460620504 1.0953831291184488 0.2879410254685434 0.1210721393219834 0.0742352733278267 0.1432798584585485 0.0561137872346343 0.00630824692371 +Abnormal circulating citrulline concentration 2 5 1.969803459700292 0.0488608999292257 1.519417475728155 4.283980582524272 0.9322911204120568 0.2795135602214257 1.0297099461920487 1.0355035731992424 1.235992875942202 0.2843671782204088 0.0091783194539023 0.0561990347849709 0.0056684159955205 0.00262770885776 0.0181181417645757 +Hallucinations 16 43 1.9664380201588656 0.0492480352256241 11.20388349514563 45.44660194174757 0.6705549628539956 0.4221278622600144 3.902598644570227 4.462852401771342 1.2595119979903464 0.3693437289960082 0.0013653675900255 0.0832266786690803 0.0714976342213511 0.0106685370568607 0.0003242201974359 +Disproportionate short limb short stature 9 18 1.965269014283112 0.049383109900488 6.587378640776699 19.902912621359224 1.344701363676014 0.2682000023842777 2.8599402401133336 3.1206003999939886 0.9439707190715964 0.2973700803613334 0.2562567496925882 1.0 0.4825947600252522 0.0824194625829831 0.4232905478115999 +Frontotemporal dementia 4 10 1.9631648282357703 0.0496270247320158 3.4344660194174756 10.344660194174756 0.5931524822816645 0.4529040772840182 1.8896952177098856 1.3751065734754873 0.9402199282689112 0.308701646569884 0.2582837389281885 1.0 1.0 0.4718643991127431 0.0353483729682259 +Young adult onset 4 11 1.9612525627728 0.0498495679951414 3.936893203883495 11.097087378640778 0.9326277418903632 0.2839315553797075 1.7793033594374144 1.2484130750505644 1.1998221427979727 0.2831359733121 0.0314966989465631 1.0 1.0 0.181169408752189 0.0181161163925661 +Xerostomia 5 15 1.9599819776064296 0.0499978968250447 4.225728155339806 15.218446601941748 0.9400183964262208 0.3676147626670514 2.1144482637513415 1.4041718405623504 0.8665256443899695 0.3037909474394171 0.163537887076428 1.0 0.3009165941166509 0.2256009180273313 0.1034478004905659 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4363f538e64a228609c268c4a17d65a44304591c --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 4549, + "title": "Average number of proteins per term", + "value": 22.47592877555507 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1d71ee2683010e690bada8d144c605603e70fbfa --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..32114e393541fbfd9e2fe6517e0b45b18ba9b91d --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1596 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Abnormal retinal artery morphology 0.6860183843369155 3.1289672493253633 0.0017542185943453 0.9996601301683936 0.3112177883331863 21 P03886,P07602,P17900,Q9NZJ7,Q9Y4P3,P10619,P00846,Q13510,P21964,P06865 10 +Dementia 0.516370164244101 3.0853401444250297 0.0020331948528884 0.9999046940831876 0.3112177883331863 60 O43464,O60220,P07602,Q9NZJ7,Q14108,P00846,P61916,P35637,Q9UHD9,P17900,Q96RR1,P04350,Q96RL7,P04062,Q13510,P21912,P03886,O76024,O60313,O00429,Q9Y487,P22626,O96008,P04080,Q9NQZ5,P06865,Q9UBB4,P05067,O15118 29 +Abnormality of head blood vessel 0.6500773636840804 3.0783402793215733 0.0020815707940786 0.9999235546540952 0.3112177883331863 24 P03886,P07602,P17900,Q9NZJ7,Q9Y4P3,P10619,P00846,Q13510,P21964,P06865 10 +Abnormal biliary tract morphology 0.6539731253357091 2.977381345130366 0.0029072215222101 0.9999982294352164 0.3112177883331863 22 P07602,P09601,Q9NZJ7,Q14108,P04062,Q10713,Q14739,Q5XKP0 8 +Corneal opacity 0.5230654418264441 2.972763438122369 0.0029513182071632 0.9999985521011492 0.3112177883331863 51 O43505,Q5H8A4,O60566,Q06136,Q15645,P08236,Q08AM6,P06280,P16278,P53701,Q6NUK1,P04062,Q13510,P51648,O75844,Q9NVI7,O75381,P04066,Q9Y4P3,P10619,P40855,O95202,Q9Y5Y5 23 +Muscle abnormality related to mitochondrial dysfunction 0.5481376410629442 2.8621942773081095 0.0042071893125776 0.9999999953148933 0.3112177883331863 37 O75306,P03886,Q96CU9,Q86Y39,O60313,Q9Y2R0,O96000,Q53H12,P12235,Q9NP80,O43676,P00846,P51530,Q9UBX3 14 +Decreased activity of mitochondrial complex iv 0.6809773923894711 2.8508025461890405 0.0043609040918146 0.99999999767869 0.3112177883331863 17 O60783,Q9Y2R0,Q70HW3,Q9Y584 4 +Central scotoma 0.7816145115909514 2.809114322658916 0.0049678002206019 0.9999999998550804 0.3112177883331863 11 Q9H061,P03886,O60220,Q9H6K4,O60313,O00429,P00846 7 +Biliary tract abnormality 0.6058242930114291 2.767379175090143 0.0056508987845746 0.9999999999936264 0.3112177883331863 24 P07602,P09601,Q9NZJ7,Q14108,P04062,Q10713,Q14739,Q5XKP0 8 +Bulbar signs 0.7426402074733257 2.7565783250199485 0.0058409621804476 0.9999999999973288 0.3112177883331863 12 P03886,P07602,Q99720,Q9NZJ7,P04062,P00846 6 +Cherry red spot of the macula 0.8370963155452392 2.7390767748338316 0.0061611983851506 0.999999999999383 0.3112177883331863 9 P07602,P17900,Q9NZJ7,P10619,P06865,Q13510 6 +Nephrotic syndrome 0.5904368912770261 2.7206038730423887 0.0065162795708237 0.9999999999998784 0.3112177883331863 25 P06280,O95470,P56192,Q07021,Q14108,Q8N1F7,Q05655,O95721,Q9BW27,Q8NCH0,Q9BT22 11 +Cns demyelination 0.6926287309875373 2.7028659971225673 0.006874445465725 0.9999999999999764 0.3112177883331863 14 Q5H8A4,P40855,Q9NR50,P07602,Q9NZJ7,Q15067,P51648 7 +Abnormal activity of mitochondrial respiratory chain 0.4870723570908274 2.6912112605954417 0.0071193095793378 0.9999999999999925 0.3112177883331863 55 P03886,Q9Y584,Q96CU9,Q86Y39,Q9Y2R0,O96000,O60783,O43676,Q7KZN9,P13073,Q9UBX3,Q70HW3 12 +Ragged red muscle fibers 0.6385780455821348 2.662485017463821 0.007756602260553 0.9999999999999996 0.3112177883331863 18 Q70HW3,P12235,Q9H2D1,P00846 4 +Mental deterioration 0.4324458919795595 2.6250521090969774 0.0086635707254916 1.0 0.3112177883331863 102 O43464,Q13057,Q86SQ9,O60220,P07602,P54802,Q9NZJ7,Q9BQE5,P36543,Q9H2C2,Q14108,Q10713,P00846,P50897,P61916,P35637,O95140,P16278,Q9UHD9,O95470,Q96RR1,P17900,P04350,Q96RL7,P04062,Q13510,P21912,O75503,O43681,P03886,O76024,O60313,P10644,O00429,P21964,Q9Y487,P22626,O75306,Q03164,Q9NPL8,Q6PI48,Q06787,O96008,P04080,Q9NQZ5,P06865,Q9UBB4,Q5XKP0,P05067,O15118 50 +Abnormal circulating lipid concentration 0.4372408320705431 2.6152803639079236 0.008915424028177 1.0 0.3112177883331863 74 Q15904,P07602,Q9NZJ7,P31751,P23786,Q9Y6B6,Q9BTV4,O43826,P50402,O75880,Q9BV10,Q15392,P61916,P06280,O95470,P40939,O75844,Q9NVI7,O75381,P50416,P28070,Q15125,O75431,Q9Y4P3,Q8N511,Q10471,P37268,Q9H9E3,P40855,Q9UJS0,Q15800,Q13045,Q14739,Q9Y5Y5,P50542,Q16836 36 +Redundant skin 0.5572023008837966 2.595114578618696 0.009455939043647 1.0 0.3186301237744478 28 Q08AM6,P51812,P38435,O96000,Q9Y4P3,Q9BV10,Q8NCH0,Q9Y487 8 +Abnormal tissue metabolite concentration 0.6719503499564543 2.5802548429981167 0.0098727427983011 1.0 0.3207936213533724 14 P06280,P40855,P07602,P17900,Q9NZJ7,P06865 6 +Abnormal visual electrophysiology 0.4843719030125918 2.547235505019155 0.0108580128727193 1.0 0.334805682880793 47 Q86SQ9,O60220,P07602,Q9NZJ7,Q92620,P00846,Q04837,Q9NRG9,P50897,O14773,O95140,Q9GZY8,Q53H12,P12235,P40939,O75503,Q8TC12,O43681,O43924,Q8N766,Q9H936,O60313,Q15067,Q15555,Q96S66,Q15042 26 +Shoulder girdle muscle weakness 0.7045773171082204 2.5461199010290754 0.0108927766687969 1.0 0.334805682880793 12 P07602,Q9NZJ7,P12235,P46976,O14979 5 +Abnormality of the mitochondrion 0.4190695385453049 2.5244471818924725 0.0115880417022349 1.0 0.3407376886116336 94 Q86Y39,Q9Y2R0,O96000,P23786,Q9BUB7,P46976,P00846,Q7KZN9,Q00325,O75880,P51530,P35637,Q9P0J0,Q9GZY8,Q96RR1,P12235,O60783,P21912,P13073,Q9UBX3,Q70HW3,P03886,Q4J6C6,Q9Y584,O43676,O00429,O75306,Q9NPL8,Q96CU9,Q16836 30 +Mitochondrial myopathy 0.5418226655157863 2.5046430663543675 0.0122575021527513 1.0 0.3407376886116336 29 O75306,P03886,Q9NPL8,Q96CU9,Q86Y39,O60313,Q53H12,O96000,P12235,Q9NP80,O43676,P00846,P51530 13 +Abnormality of corneal stroma 0.749926885756616 2.5038723626166193 0.0122842341025077 1.0 0.3407376886116336 10 Q13510,P04062,P16278,P10619 4 +Increased cerebral lipofuscin 0.9080724876441476 2.495688853976336 0.0125712816910643 1.0 0.3465864267433442 5 P07602,Q9NZJ7,P50897,O75503 4 +Airway obstruction 0.6659388281108931 2.4829100227126064 0.0130313998996001 1.0 0.3487629822056428 13 P06280,P09601,P16435,P21964,O75844 5 +Optic disc pallor 0.4720093441106863 2.477657437428831 0.0132248049213417 1.0 0.3487629822056428 51 Q9H061,O75306,P03886,Q96L58,Q9GZY8,Q86Y39,Q9H6K4,O60313,Q96CU9,O96000,Q9UG56,Q13277,O43676,Q86WC4,O00429,Q10713,P00846 17 +Abnormality of skull ossification 0.6429508016509258 2.4690423791744065 0.0135475173133339 1.0 0.3523567943484678 15 Q08AM6,Q9HC21,Q6NUK1,Q86WC4,Q14739,O75844,P54802 7 +Disproportionate short stature 0.5707420403674007 2.4537906257519575 0.0141359260461511 1.0 0.3523567943484678 23 Q9UHX1,Q03164,O75718,Q96HY6,P16278,Q15125,P10644,O43909,Q9BV10,Q15392,P42345,Q14739,Q7LGA3 13 +Abnormality of glycolipid metabolism 0.8187067256631154 2.438293686872081 0.0147567795721668 1.0 0.3530420312755609 7 P07602,P17900,Q9NZJ7,P06865 4 +Horizontal nystagmus 0.5672133581320925 2.428042000248285 0.0151805851620276 1.0 0.3530420312755609 23 Q9H061,P07602,O60313,Q9NZJ7,P04062,P00846,O14773 7 +Laryngomalacia 0.7082250846600081 2.41914656032434 0.015556970763966 1.0 0.3530420312755609 11 Q9NZJ7,P21964,P16435 3 +Ascites 0.5372834328230306 2.4105818274247257 0.0159270981016799 1.0 0.3530420312755609 27 Q14108,Q01844,P16930,Q86WC4,P04062,O60566,Q13510,Q14739,Q15645,P61916,P08236,O15118 12 +Abnormal circulating cholesterol concentration 0.513940828620857 2.4092031810221233 0.0159873946895505 1.0 0.3530420312755609 33 Q15904,P07602,Q9NZJ7,Q9Y6B6,Q9BTV4,O43826,P50402,Q9BV10,Q15392,P61916,Q9NVI7,Q15125,O75431,Q8N511,Q10471,Q9H9E3,P37268,Q9UJS0,Q15800,Q13045,Q14739 21 +Abnormality of the larynx 0.4749505270191474 2.398943585308121 0.016442447694897 1.0 0.3613366887153935 41 Q9UHX1,Q96HY6,P07602,Q9NZJ7,Q15165,P16435,Q14739,Q13510,P21964,P35637 10 +Blindness 0.4183239920801567 2.390125487740226 0.0168426169485298 1.0 0.3651885573912742 74 O43505,Q86SQ9,Q86Y39,P07602,Q9NZJ7,O96000,Q92620,P00846,P50897,P16278,Q9H6K4,P17900,P53701,Q969G3,P21912,P03886,O43676,Q9NZ08,O75306,Q9NPL8,P49770,Q96CU9,Q9NR50,P06865 24 +Abnormal lower motor neuron morphology 0.8060961717517177 2.379998714440955 0.0173126984492228 1.0 0.3653263615958722 7 Q99720,Q13510 2 +Dysostosis multiplex 0.7928640624904345 2.353021223169328 0.0186215712202508 1.0 0.3868014953466723 8 P16278,P54802,P04066,P10619,P15586,P08236 6 +Abnormally lax or hyperextensible skin 0.4669813795889959 2.347844342759717 0.0188824105133553 1.0 0.3869948746369264 44 Q08AM6,Q9UHX1,P51812,P38435,O96000,Q9Y4P3,Q6NUK1,P04062,Q9BV10,Q8NCH0,Q9Y487,Q9NWM8 12 +Periventricular white matter hyperintensities 0.795287102930659 2.3297021999984686 0.0198218961948568 1.0 0.3869948746369264 7 P17900,Q9NZJ7,O75503 3 +Abnormal larynx morphology 0.5525541197525053 2.3202425423700954 0.0203277604080096 1.0 0.3915872618208199 23 Q9UHX1,P07602,Q9NZJ7,P16435,Q14739,Q13510,P21964 7 +Splenomegaly 0.3965517980704318 2.3179507293395107 0.0204519989572911 1.0 0.3915872618208199 85 P54802,P07602,Q9NZJ7,Q14108,P10253,Q10713,Q15392,Q9BT22,P61916,P08236,Q96A33,P16278,P04062,Q13510,P15586,P28070,Q86WC4,P21964,Q9NZ08,Q96HY6,Q05655,Q14739,O15118 23 +Muscle stiffness 0.596564569868261 2.3101032928769003 0.0208824361886921 1.0 0.3934147847815205 17 Q9NZJ7,P23786,Q15392,P00846 4 +Ventricular preexcitation 0.8124451202538787 2.3095737359846944 0.0209117650576924 1.0 0.3934147847815205 6 O60783,P03886,P10253,P00846 4 +Elevated pulmonary artery pressure 0.5357433748669561 2.30926143198921 0.0209290784605689 1.0 0.3934147847815205 25 Q08AM6,P03886,Q8IZA0,Q5T2R2,O96000,Q14108,Q6NUK1,P04062,O75844 9 +Macular degeneration 0.6874114639714761 2.305045449378612 0.0211640281291873 1.0 0.3950368585289206 11 P51648,P50897,Q13510 3 +Schizophrenia 0.5798452388951401 2.271431322876005 0.0231208800357387 1.0 0.4041297025431894 18 O76024,P07602,Q9NZJ7,Q9BQE5,P04062,P21964 6 +Abnormal lung lobation 0.6304295284084388 2.2701263225336765 0.0231999196595178 1.0 0.4041297025431894 13 Q9UHX1,P21964 2 +Abnormal chorioretinal morphology 0.5378703822413508 2.2664856942213594 0.0234216620759248 1.0 0.4041297025431894 24 O43505,P40855,P53701,Q9Y619,P04439,Q10713,P40939,O14936,Q9Y5Y5,P50542,Q5XKP0,O75381 12 +Chronic fatigue 0.8536842972882815 2.2641534056476007 0.0235646812258893 1.0 0.4041297025431894 5 Q9NZJ7,Q13423 2 +Abnormality of prothrombin 0.654578507570307 2.2611224243407295 0.0237516771399719 1.0 0.4041297025431894 12 P38435,Q9UJS0,Q6NUQ1,Q9BV10,Q5XKP0,Q16836 6 +Abnormal vascular physiology 0.4490933202076131 2.2595685603093636 0.0238480407093921 1.0 0.4041297025431894 52 Q08AM6,P03886,Q8IZA0,P06280,O96000,Q9Y4P3,Q14108,Q6NUK1,P04062,Q14739,Q9NZ08,O75844,Q9NWM8,P05067 14 +Abnormal retinal vascular morphology 0.4543859918888265 2.253482178823872 0.0242287631481386 1.0 0.4041297025431894 47 Q86SQ9,P07602,Q9NZJ7,Q92620,O43826,P00846,P16278,P17900,P04439,Q13510,P21912,P03886,Q9Y4P3,Q15555,P10619,P21964,O75306,P38435,P06865 19 +Hypocholesterolemia 0.7370328142500984 2.2507373973688956 0.0244021746531815 1.0 0.4041297025431894 9 P07602,Q9NZJ7,Q15800,Q9BV10,Q9NVI7,P37268 6 +Scotoma 0.6177993592735486 2.250224077349972 0.0244347246212159 1.0 0.4041297025431894 14 Q9H061,O75306,P03886,Q9H6K4,O60220,O60313,O00429,P00846 8 +Abnormality of pulmonary circulation 0.5095412323417319 2.244016853096334 0.0248313170203309 1.0 0.4041297025431894 29 Q08AM6,P03886,Q8IZA0,Q5T2R2,O96000,Q14108,Q6NUK1,P04062,Q9NZ08,O75844 10 +Polyneuropathy 0.5744298537792739 2.234449463188349 0.0254535142295921 1.0 0.4067853956756794 18 P03886,Q9HC21,Q6PI48,P07602,P04066,Q9NZJ7,O60313,O95721,P00846,Q15041 10 +Psychomotor deterioration 0.7334500029444336 2.232697802067523 0.0255688795046866 1.0 0.4067853956756794 9 Q9Y487,Q9NZJ7,P50897,P06865 4 +Abnormal circulating non proteinogenic amino acid concentration 0.7674592809037193 2.232605234648426 0.025574988604802 1.0 0.4067853956756794 8 Q9Y619,P05067,P00846 3 +Abnormal macular morphology 0.5398685251312129 2.225865740744102 0.0260231757332447 1.0 0.4124718690262382 23 Q13510,P51648,P50897,Q86SQ9 4 +Segmental peripheral demyelination remyelination 0.8408135081445649 2.208458950294626 0.0272122963246701 1.0 0.4210501223840969 5 P00846 1 +Decreased activity of mitochondrial complex i 0.4820594958367713 2.206146706754166 0.0273737293226465 1.0 0.4221121853854893 35 P03886,Q9Y584,Q96CU9,Q86Y39,O43676,Q9UBX3,Q70HW3 7 +Microdontia 0.5125023639695861 2.188663986379411 0.0286212713800422 1.0 0.4294050300758174 26 Q96A33,Q9Y4P3,Q9Y619,Q6NUK1,P07237,Q9Y487,Q7LGA3 7 +Supranuclear gaze palsy 0.5671050319651582 2.1841754059358136 0.0289493614086677 1.0 0.4294050300758174 18 P35637,P07602,Q99720,Q9NZJ7,P04062,P61916,O15118 7 +Clumsiness 0.5544757961518787 2.1828545364048892 0.0290465239870092 1.0 0.4294050300758174 20 O43681,Q6PI48,P07602,Q9NZJ7,Q96RR1,O00754,Q15067,Q13510,O14773,O00165,O75503 11 +Progressive visual loss 0.5578093854769155 2.1618454200128308 0.0306300931860772 1.0 0.4480266684998885 19 O75306,P03886,P50897,O60313,O00429,P00846,O14773,O75503 8 +Neuronal loss in central nervous system 0.6361726962133945 2.153697017544878 0.0312639401960652 1.0 0.4543759231690124 12 Q08AM6,P07602,Q9NZJ7,P04062,O15118 5 +Episodic vomiting 0.6820274773878912 2.145309248488648 0.0319281295362876 1.0 0.4596236115840902 10 Q9Y619,P00846,Q9NP80 3 +Delusions 0.5608405904550844 2.140948387066273 0.0322782004765274 1.0 0.4631972680369816 18 P49770,Q9UJS0,Q9NR50,P07602,O60220,Q9NZJ7,O00754,Q9BQE5,Q96RL7,P04062,P21964 11 +Abnormal pupillary function 0.8233138170018784 2.1321823745044286 0.0329918568395417 1.0 0.4657340128656025 5 Q9NZJ7 1 +Postural tremor 0.553373581039363 2.130667207524505 0.0331165684675283 1.0 0.4657340128656025 19 O75306,P03886,Q9H6K4,P04350,Q14108,P00846,Q06787,O14773,O75569,P35637 10 +Optic neuropathy 0.5339507010162151 2.129669495295763 0.0331989091313431 1.0 0.4657340128656025 22 Q9P0J0,O75306,P03886,Q96CU9,Q86Y39,O96000,O43676,P00846 8 +Capillary hemangioma 0.7527424317666936 2.128761132094597 0.0332740281779118 1.0 0.4657340128656025 7 Q9UHX1,Q7LGA3 2 +Abnormal epiphyseal ossification 0.5684672346570926 2.122138670093258 0.0338260949028474 1.0 0.4720089132302247 17 P38435,P40855,Q96HY6,Q96L58,O00116,Q15125,Q9UG56,P10644,Q14739,Q9Y5Y5,O75381,P08236 12 +Mucosal telangiectasiae 0.7492274487680899 2.111947100686527 0.0346909868267459 1.0 0.4811259118136204 7 Q14739,Q8IZA0,P10619 3 +Arthritis 0.4573651197496653 2.0982501841611514 0.0358830505893519 1.0 0.4946424155483694 38 P06280,Q96HY6,P28070,Q14108,Q05655,P04062,Q14739,Q13510,P21964,Q9NZ08,O75844 11 +Amyotrophic lateral sclerosis 0.5733459706837789 2.0883524234273936 0.0367660557982376 1.0 0.4966159759884108 16 Q99720,Q15165,Q92804,P22626,P35637 5 +Slow decrease in visual acuity 0.7440228074935228 2.0869910355829955 0.0368889448848661 1.0 0.4966159759884108 7 O75306,P03886,O00429,P00846 4 +Urinary glycosaminoglycan excretion 0.7434707271921702 2.0843396673803594 0.0371292815563113 1.0 0.4966159759884108 7 P15586,P54802,P16278,P08236 4 +Calcinosis 0.8120751164976234 2.0828624764265142 0.037263760790819 1.0 0.4966159759884108 5 O75844 1 +Abnormality of the posterior pituitary 0.7619108410463596 2.076509818425031 0.0378468239934777 1.0 0.4974690803767568 6 Q9UHX1,O76024 2 +Lower limb spasticity 0.3801797867707584 2.072902041036803 0.0381813970536586 1.0 0.4974690803767568 79 Q6DKK2,Q99720,P07602,Q9NZJ7,P00846,Q7KZN9,Q9BTW9,P35637,Q9P0J0,Q9H6K4,O00400,P04062,P21912,O60313,O00754,P56192,Q9Y619,O00429,O94905,Q15041,O75306,Q96CU9,Q9Y5Y5,Q5XKP0 24 +Prolonged partial thromboplastin time 0.7607462073187643 2.071065490328504 0.0383526762965196 1.0 0.4974690803767568 6 P38435,Q9BV10,O60762 3 +Myoclonus 0.3805397200381063 2.069046525026921 0.0385417210352811 1.0 0.4974690803767568 89 P03886,Q96CU9,Q86SQ9,P07602,Q9NZJ7,Q14108,Q9NQZ5,P04062,Q10713,Q13510,P00846,P00374,P13073,P50897,Q9UBX3,P05067,O75503 17 +Abnormality of extrapyramidal motor function 0.3987315754287843 2.0680622547538245 0.0386341694374845 1.0 0.4974690803767568 71 Q6DKK2,Q86SQ9,O14949,P07602,Q99720,Q9NZJ7,Q9H6K4,P17900,P12235,Q9Y4P3,P04062,P06865,P05067,P35637 14 +Perimembranous ventricular septal defect 0.7594460720507761 2.064983867812752 0.0389245267206712 1.0 0.4974690803767568 6 Q9UHX1 1 +Abnormal aortic arch morphology 0.7393373220574351 2.0644636280239324 0.0389737790392463 1.0 0.4974690803767568 7 Q9UHX1 1 +Abnormal enchondral ossification 0.4940073919453759 2.063834813835163 0.039033381001881 1.0 0.4974690803767568 27 O75381,Q08AM6,P38435,Q96L58,P40855,Q96HY6,Q15125,O00116,O96028,O95202,Q9UG56,Q9Y619,P10644,O43909,Q14739,Q9Y5Y5,P50542,P08236 18 +Abnormality of the vasculature of the eye 0.4045159939438933 2.062431856284836 0.0391666390098537 1.0 0.4974690803767568 68 P03886,P06280,P38435,Q86SQ9,P07602,P28070,Q9NZJ7,P17900,Q9Y4P3,P10619,Q14739,P00846,Q13510,P21964,Q9NZ08,P06865 16 +Abnormal larynx physiology 0.5872289384579641 2.0580373569476547 0.0395865475088965 1.0 0.4974690803767568 14 Q92804,Q15165,Q13510,P35637 4 +Abnormal light and dark adapted electroretinogram 0.7374847045948931 2.0555405666861395 0.039826821610166 1.0 0.4974690803767568 7 Q15067,P50897,P00846 3 +Abnormal full field electroretinogram 0.7374847045948931 2.0555405666861395 0.039826821610166 1.0 0.4974690803767568 7 Q15067,P50897,P00846 3 +Metatarsus adductus 0.5949597027377415 2.0520697055199957 0.040162888598787 1.0 0.499100969356062 13 Q08AM6,Q96L58,O96028,O95202,Q15392,P08236 6 +Cutis laxa 0.4722008295285196 2.049512685816397 0.0404120086559622 1.0 0.4995495309129686 33 Q08AM6,P51812,P38435,O96000,Q9Y4P3,Q6NUK1,Q9BV10,Q8NCH0,Q9Y487 9 +Arthralgia 0.4821905367653057 2.0445718552297127 0.0408970866036104 1.0 0.5014578085170459 30 P06280,P28070,Q15800,Q9Y4P3,Q05655,Q13510,Q9NZ08 7 +Occipital encephalocele 0.7529801235703208 2.0346777673325125 0.0418833066761645 1.0 0.508072432186327 6 Q6ZXV5,Q10713 2 +Abnormality of the distal phalanges of the toes 0.7523273585930108 2.031612655521695 0.0421928844893324 1.0 0.509112550509213 6 O75844,Q7LGA3 2 +External ophthalmoplegia 0.5546284678663483 2.028055632031727 0.0425545704569125 1.0 0.5105743439653483 17 P03886,Q9GZY8,O60313,Q96RR1,P12235,Q07021,P51530 7 +Atrophy degeneration involving the corticospinal tracts 0.6145473780309711 2.025734157667467 0.0427920343665715 1.0 0.5105743439653483 12 O00400,Q9Y4P3,P00846 3 +Dolichocephaly 0.4858438896121516 2.0215660619168614 0.0432212011261641 1.0 0.5105743439653483 28 Q08AM6,Q5H8A4,Q4J6C6,Q9BXW9,Q03164,P40855,O96028,O95202,P61978,O95721,Q9Y5Y5,O75381 12 +Turricephaly 0.691985436237094 2.021074543961073 0.0432720490486757 1.0 0.5105743439653483 9 Q6NUK1,P21964,P16435 3 +Sclerocornea 0.6917042310405612 2.0196214572699036 0.0434226677101787 1.0 0.5105743439653483 9 Q08AM6,Q5H8A4,P53701,O96028,O95202,Q6NUK1,O75569 7 +Impaired vibration sensation in the lower limbs 0.5885731201617104 2.0122177598580997 0.0441969871611065 1.0 0.5159909859804576 13 P00846 1 +Mania 0.6120713299277224 2.0109622892931105 0.0443294400951319 1.0 0.5159909859804576 12 P51812,P03886,Q96RR1,P12235,P16615,P21964 6 +Lacticaciduria 0.7949958518539395 2.007417987815513 0.0447051750943574 1.0 0.5174652455578423 5 P03886,P00846 2 +Abnormal choroid morphology 0.4967227951445864 2.003516887401996 0.0451218368235162 1.0 0.5175103423549317 25 O43505,P40855,P53701,Q9Y619,P04439,Q10713,P40939,O14936,Q9Y5Y5,P50542,Q5XKP0,O75381 12 +Abnormality of the alveolar ridges 0.7266027611201199 2.002947404458943 0.0451829341436278 1.0 0.5175103423549317 7 Q08AM6,Q15392 2 +Undetectable electroretinogram 0.7937887775829385 2.002063627124382 0.0452778888233156 1.0 0.5175103423549317 5 O43924,P50897 2 +Primary adrenal insufficiency 0.5855866906892063 1.993520987505259 0.0462044277122606 1.0 0.5237640363441886 13 P40855,Q969G3,P16435,Q9Y5Y5,P50542,Q13423,O75381 7 +Hydrocephalus 0.3913734300596409 1.9785546558266465 0.0478661691898083 1.0 0.5237640363441886 71 O43505,Q96L58,P23786,Q10713,Q15392,O60566,P08236,Q08AM6,P53701,Q969G3,P16435,Q6NUK1,P07237,P04062,P15291,O00754,Q86WC4,P21964,P40855,O95202 20 +Pulmonary infiltrates 0.721346349531399 1.9774325886734596 0.047992753345698 1.0 0.5237640363441886 7 Q9NZ08,P04062,Q13510 3 +Peripheral demyelination 0.5470955857085941 1.976425976471272 0.0481065518971188 1.0 0.5237640363441886 17 Q9NZJ7,P03886,P00846 3 +Mitochondrial respiratory chain defects 0.7392754498861213 1.970112578579437 0.0488254696328021 1.0 0.5237640363441886 6 P03886,Q4J6C6,P00846 3 +Abnormal circulating citrulline concentration 0.7865300044167892 1.969803459700292 0.0488608999292257 1.0 0.5237640363441886 5 Q9Y619,P00846 2 +Hallucinations 0.429058513700417 1.9664380201588656 0.0492480352256241 1.0 0.5237640363441886 43 O75503,Q6DKK2,O76024,Q9UJS0,P07602,O60313,Q9NZJ7,Q9BQE5,O00754,O96008,P04062,O00429,P21964,P50897,P05067,P35637 16 +Disproportionate short limb short stature 0.5356919710825331 1.9652690142831115 0.049383109900488 1.0 0.5237640363441886 18 Q03164,O75718,Q15125,P10644,Q14739,P42345,Q15392,Q9BV10,Q7LGA3 9 +Frontotemporal dementia 0.6486300213656122 1.9631648282357703 0.0496270247320158 1.0 0.5237640363441886 10 P05067,O96008,P22626,P35637 4 +Young adult onset 0.626381642713034 1.9612525627728 0.0498495679951414 1.0 0.5237640363441886 11 P07602,Q9NZJ7,P38435,O15118 4 +Xerostomia 0.5631787460720791 1.9599819776064296 0.0499978968250447 1.0 0.5237640363441886 15 Q9UHD9,Q15165,Q14739,Q92804,P35637 5 +Posterior embryotoxon 0.534759482475319 1.958689126749083 0.0501492045940714 1.0 0.5237640363441886 18 P40855,P53701,Q9Y4P3,P21964,O75381,Q7LGA3 6 +3 methylglutaconic aciduria 0.6259324596081298 1.9586710288846867 0.0501513253842944 1.0 0.5237640363441886 11 Q9H6K4,Q3ZCQ8,Q53H12,Q9BUB7,Q5XKP0,Q9NVI7 6 +Paraparesis 0.480983701089273 1.956839274444261 0.0503663679360404 1.0 0.5237640363441886 27 Q6DKK2,Q9H6K4,Q9Y619,P04062,Q13510,Q5XKP0 6 +Progressive external ophthalmoplegia 0.647383709757595 1.9562936933363808 0.0504305667000999 1.0 0.5237640363441886 10 P03886,O60313,P12235,Q07021,P51530 5 +Biliary cirrhosis 0.7360969741970786 1.9550743904651064 0.0505742904917183 1.0 0.5240602447535918 6 P09601,Q14739 2 +Morphological abnormality of the corticospinal tract 0.5708372667326275 1.95322552315246 0.0507928780129349 1.0 0.5251290956382754 14 O00400,Q9Y4P3,P00846 3 +Hepatic failure 0.4226456734132726 1.9509509875952435 0.0510628764403822 1.0 0.526723412533557 49 P23786,Q6NUQ1,Q10713,P00846,P28288,Q9P2J5,P04062,P40939,Q13510,O75381,P50416,P03886,Q9Y619,P16930,Q86WC4,O15460,Q9H9E3,P40855,Q9Y5Y5,Q16836,O15118 21 +Generalized joint laxity 0.6239695640214729 1.9473811958525669 0.0514890507520136 1.0 0.5275407949937453 11 Q9UHX1,Q8NCH0 2 +Reduced visual acuity 0.3823658314137869 1.9374771681606109 0.0526870416826767 1.0 0.5321824908408278 106 O43505,Q9UHX1,Q86SQ9,Q86Y39,O60220,P07602,Q9NZJ7,O96000,Q07021,Q10713,P00846,P50897,P16278,Q9H6K4,P17900,P53701,Q9H061,P03886,O60313,O43676,O00429,Q9NZ08,O75306,Q9NPL8,Q96CU9,Q9NR50,Q13277,P06865 28 +Basal ganglia cysts 0.7131430130087504 1.937470666982037 0.0526878356519924 1.0 0.5321824908408278 7 P00846 1 +Abnormal electroretinogram 0.4663078624655743 1.9368638175735229 0.0527619923871649 1.0 0.5321824908408278 31 O43924,Q86SQ9,O60220,P50897,Q53H12,Q92620,P12235,Q15067,Q15555,P00846,O14773 11 +Abnormality of chorioretinal pigmentation 0.9091534108646636 1.9323350075792711 0.0533181701926581 1.0 0.5342386700581542 4 Q9Y619 1 +Hemivertebrae 0.6194654669226856 1.921421718209438 0.0546785626802504 1.0 0.5359089495214413 11 Q9Y619,Q9UHX1 2 +Degeneration of the lateral corticospinal tracts 0.7743039820670907 1.9152308948914376 0.0554630641004212 1.0 0.5359089495214413 5 O00400 1 +Abnormality of visual evoked potentials 0.5112360927196258 1.9130477000869108 0.0557419462085324 1.0 0.5359089495214413 21 O95140,Q8TC12,O43681,Q8N766,Q9H936,Q9GZY8,O60220,P07602,O60313,Q9NZJ7,Q15067,Q15042,Q9NRG9,O75503 14 +Toe walking 0.492115180987007 1.9123589915303356 0.0558301641042811 1.0 0.5359089495214413 24 O43681,P07602,Q99720,Q9NZJ7,Q9BTV4,Q9NP80,P40939,P50402,O95831,P35637 10 +Retinal vascular tortuosity 0.5950816160104699 1.9089390349815387 0.0562699566981019 1.0 0.5359089495214413 12 P03886,P00846,P21964 3 +Chronic pulmonary obstruction 0.7256197681141326 1.9053355450899887 0.0567364678016639 1.0 0.5365940682367959 6 P09601,P21964 2 +Elevated hepatic transaminase 0.3732078668748657 1.9044155373390728 0.0568560872477765 1.0 0.5365940682367959 96 Q86SQ9,Q15904,Q9Y6B6,P23786,Q6NUQ1,Q07021,P10253,Q9BV10,Q10713,O43826,O75880,P28288,Q9P2J5,Q96RR1,P12235,Q96RL7,Q13510,Q9Y5U9,P50416,P28070,P56192,Q15067,Q9Y619,P16930,Q8N511,Q9H9E3,Q9HC07,P40855,Q9UJS0,O60762,Q05655,Q14739,Q9Y5Y5,Q5XKP0,Q16836 35 +Hemiparesis 0.5631074551028905 1.9033749079097084 0.0569916427661409 1.0 0.5367597990541934 14 P03886,O60313,Q969G3,Q9NP80,P49327,O00429,P11166,P42345,Q9NZ08 9 +Morphological abnormality of the pyramidal tract 0.509668138743264 1.9013377180854725 0.0572577916668999 1.0 0.5381522609353879 21 Q9Y619,O00400,Q9Y4P3,P00846 4 +Hypertrophic cardiomyopathy 0.3790880204601448 1.884384578957076 0.0595129742331146 1.0 0.5492863916935534 107 Q86Y39,O96000,Q9BUB7,P10253,P50402,P00846,Q00325,Q7KZN9,Q9P0J0,P06280,P16278,Q53H12,P53701,P12235,O60783,Q96I36,P21912,Q9NVI7,P15586,Q99797,Q9H061,P03886,O60313,Q9Y4P3,O43676,P16930,O75306,Q9NPL8,Q96CU9,Q5XKP0,Q16836,Q13423,P54802 33 +Epiphyseal stippling 0.5682161627386404 1.8839969653332955 0.0595653859546048 1.0 0.5492863916935534 13 P38435,P40855,O00116,Q15125,P10644,Q14739,Q9Y5Y5,O75381,P08236 9 +Recurrent aspiration pneumonia 0.7189802056937498 1.873682645668372 0.0609741792840763 1.0 0.5560041187310705 6 P04062,Q13510 2 +Abnormal elasticity of skin 0.401988979330238 1.872696764659334 0.0611102703930037 1.0 0.5560041187310705 60 Q08AM6,Q9UHX1,P51812,P38435,Q9Y487,O96000,Q9Y4P3,Q13126,Q6NUK1,P04062,Q9BV10,Q8NCH0,O75844 13 +Mitochondrial inheritance 0.7633259058462245 1.865979969478141 0.0620441679808936 1.0 0.5614957491408975 5 P00846 1 +Paraplegia paraparesis 0.3734722747610845 1.8625391534205271 0.0625271319054765 1.0 0.5614957491408975 75 Q6DKK2,Q96L58,Q7KZN9,P00846,P35637,Q9P0J0,Q9H6K4,O00400,P04062,Q13510,P21912,O60313,O00754,P56192,Q9Y619,O00429,O94905,O75306,Q96CU9,Q9Y5Y5,Q5XKP0 21 +Abnormal csf protein level 0.6613204711832225 1.8612093041525928 0.0627146249763928 1.0 0.5614957491408975 9 P07602,Q9NZJ7,P03886,P55011 4 +Nasogastric tube feeding in infancy 0.6910577012001067 1.859880883771815 0.0629023804862065 1.0 0.5614957491408975 8 Q9UHX1,Q9NZJ7 2 +Abnormality of hepatobiliary system physiology 0.368335585002776 1.8545729721363104 0.0636572307017377 1.0 0.5614957491408975 77 P23786,Q6NUQ1,Q10713,P00846,Q9BT22,P28288,Q9P2J5,O43819,Q96A33,O75648,P22695,P04062,P40939,Q13510,O75381,P50416,P03886,P56192,Q9Y619,Q15031,Q86WC4,P16930,O15460,Q8N511,Q9H9E3,O75306,P40855,P50542,Q9Y5Y5,Q5XKP0,Q16836,O15118 32 +Clonus 0.459950725803562 1.8542118428103904 0.0637088584455041 1.0 0.5614957491408975 30 Q53FT3,O60220,P07602,Q99720,Q9NZJ7,Q9Y619,O00400,Q86WC4 8 +Hypothermia 0.6896824526427976 1.8530274966683784 0.0638784176190037 1.0 0.5614957491408975 8 Q5XKP0,P00846 2 +Impaired proprioception 0.42318410882264 1.852720980248524 0.0639223612856954 1.0 0.5614957491408975 40 O95140,O43819,Q6PI48,Q9H6K4,Q96RR1,Q9Y6B6,O00165,Q06787,Q9Y619,Q96RL7,O00400,O94905,P00846,Q13217,O14773,Q8IV08,P54802 17 +Social and occupational deterioration 0.9716919025674746 1.8517507930737416 0.0640616165759784 1.0 0.5614957491408975 2 Q9BQE5 1 +Negativism 0.9716919025674746 1.8517507930737416 0.0640616165759784 1.0 0.5614957491408975 2 Q9BQE5 1 +Cerebral inclusion bodies 0.5534272268241347 1.8405655479088388 0.0656852503699887 1.0 0.5737522202083377 14 P04062,P05067,P61916,P22626,O15118 5 +Arteriosclerosis 0.6054614492164282 1.8402348939656636 0.0657337591353732 1.0 0.5737522202083377 11 P38435,P16278,Q13510,O75844,O15118 5 +Abnormal middle phalanx morphology of the hand 0.6571627521706707 1.8393170225426057 0.0658685707371768 1.0 0.5737522202083377 9 Q9UHX1 1 +Constriction of peripheral visual field 0.5070436624410768 1.838664974215225 0.0659644781642032 1.0 0.5737522202083377 20 Q9H061,P40855,O60220,O60313,P00846,Q9Y5Y5,O75381 7 +Hypoplastic vertebral bodies 0.7555070396859156 1.8307615182497683 0.0671361464114426 1.0 0.5828288740947566 5 P10644,Q14739,P16278 3 +Hypersplenism 0.6843942681190859 1.8266280149509833 0.0677557182299954 1.0 0.5849113999683198 8 P07602,Q9NZJ7,Q05655,P04062 4 +Abnormality of femur morphology 0.3900759505440345 1.8265877704528448 0.0677617735289743 1.0 0.5849113999683198 65 Q9UHX1,O75718,Q96L58,P07602,Q9NZJ7,Q6NUQ1,O43909,Q9BV10,Q96A33,P06280,Q9BXW9,P16278,P16435,P04062,O75844,P04066,O00754,O75431,Q9Y619,Q9Y487,Q9H9E3,Q7LGA3,P51812,Q96HY6,O00116,Q14739,P50542,O95831,P55011 29 +Increased bone mineral density 0.4809181877503001 1.823612246116776 0.0682107138829615 1.0 0.5876714724499847 24 Q9Y4P3,Q14108,Q13126,Q86WC4,P04062,Q14739,Q15392 7 +Hand polydactyly 0.4621346905235193 1.8227437191646152 0.0683422153963759 1.0 0.5876913758754524 28 Q9UHX1,Q5H8A4,Q9BXW9,O43924,Q15125,O96028,O95202,Q15067,O43909,Q10713,Q14739,P21964,Q9UM00 13 +Abnormal macrophage morphology 0.7068690027099754 1.815683658559487 0.0694189122189952 1.0 0.5903340389081364 6 Q13510,Q86WC4,P16278,O15118 4 +Unexplained fevers 0.7065538718435725 1.814170088238598 0.0696515437240443 1.0 0.5903340389081364 6 Q9HC07,Q9NZJ7 2 +Abnormal circulating long chain fatty acid concentration 0.7516817417572117 1.8134893415001565 0.0697563810544601 1.0 0.5903340389081364 5 P23786,P40855,O75381 3 +Left ventricular hypertrophy 0.5035886886901746 1.8130929963313167 0.0698174792113821 1.0 0.5903340389081364 20 P03886,P06280,P21912,Q96RR1,P12235,Q07021,Q6NUK1,P10253,P40939,O75880 10 +Rhizomelia 0.6005455034555921 1.8115664231709163 0.0700532169991807 1.0 0.5912283564550525 11 Q03164,O75718,Q15125,Q14739,P42345,Q15392,Q9BV10 7 +Abnormal circulating progesterone level 0.7508453720787159 1.8097092917107416 0.0703408808460093 1.0 0.591461491623838 5 P16435,Q9NR50 2 +Decreased circulating progesterone 0.7508453720787159 1.8097092917107416 0.0703408808460093 1.0 0.591461491623838 5 P16435,Q9NR50 2 +Abnormality of the upper respiratory tract 0.3624038315299963 1.8052584704818968 0.0710342450668208 1.0 0.5945559404204905 91 Q9UHX1,P07602,Q9NZJ7,O43909,Q9BV10,Q92804,P08236,P35637,Q9H0U3,P16278,Q9UHD9,Q969G3,P16435,Q13510,Q03518,P15586,P04066,P28070,O00754,Q15165,P10644,P21964,Q96HY6,Q13277,Q05655,Q14739,P54802 27 +Progressive psychomotor deterioration 0.6795262291104254 1.802261158581069 0.0715043264754611 1.0 0.5954625787825277 8 P16278,P07602,Q9NZJ7,Q10713,P21912 5 +Abnormality of fontanelles 0.4115456313892882 1.8021081958634624 0.0715283844869727 1.0 0.5954625787825277 45 P51812,P40855,Q9Y487,P16435,Q9Y619,Q6NUK1,Q8NCH0,Q9BT22,O75844 9 +Ankylosis 0.749060852771357 1.801639660729711 0.0716021170793674 1.0 0.5954625787825277 5 O75844 1 +Preaxial hand polydactyly 0.6782411683147292 1.795818512194217 0.0725233855606934 1.0 0.600926923343524 8 Q9UHX1,Q5H8A4,Q9BXW9,O95202,O43909 5 +Oromandibular dystonia 0.7009617924055171 1.7872743185158384 0.0738931626796659 1.0 0.6097976270163246 6 Q99720,Q96RL7,P35637,O60220 4 +Eeg with focal spikes 0.7457467008824317 1.786637436839137 0.0739961068615104 1.0 0.6097976270163246 5 Q5H8A4 1 +Ventricular arrhythmia 0.4238867110325898 1.7799542977040586 0.0750834404357347 1.0 0.61336036751516 38 O75306,P03886,Q9HD47,P0DP25,Q96RR1,P23786,P12235,O60783,P42892,P46976,P10253,P50402,P00846 13 +Central apnea 0.6750571991559466 1.779837250541279 0.0751025994077696 1.0 0.61336036751516 8 P07602,Q9NZJ7,Q10713 3 +Cogwheel rigidity 0.7429548499543421 1.773983936777523 0.076065807362752 1.0 0.619043424828723 5 P00846 1 +Loss of speech 0.5036878740430244 1.7739548110926813 0.0760706252977041 1.0 0.619043424828723 19 P07602,P17900,Q9NZJ7,O00754,P50897,P61916,O15118 7 +Abnormality of the metacarpal bones 0.4306789070242364 1.772563195342726 0.0763011149191681 1.0 0.6198103067273141 36 Q08AM6,O43924,P51812,Q9BXW9,Q96L58,P16278,Q9NX62,O95202,P16435,Q96S52,Q6NUK1,P10644,O43909,Q14739,Q9H9E3,P08236 16 +Hyperconvex nail 0.679280608961363 1.7707045053889734 0.0766098528812413 1.0 0.6201035956526101 7 P42892,Q9Y619,P51812,O95202 4 +Global brain atrophy 0.4920044504492258 1.7684308277430518 0.0769889066825724 1.0 0.6220648960906251 21 Q9UHX1,O60220,P07602,Q9NZJ7,P00387 5 +Upper limb spasticity 0.6967402788134505 1.7669243179808511 0.0772409038094281 1.0 0.6229944528884552 6 Q99720,Q9BTW9,P35637 3 +Slow pupillary light response 0.8677347999494054 1.7634702810744434 0.0778212053638336 1.0 0.6234390725774221 4 Q9NZJ7 1 +Abnormal pupillary light reflex 0.8677347999494054 1.7634702810744434 0.0778212053638336 1.0 0.6234390725774221 4 Q9NZJ7 1 +Pathologic fracture 0.5251749400621004 1.7633336802431023 0.0778442280114257 1.0 0.6234390725774221 16 Q9Y5U9,Q96L58,Q14108,Q13126,O15269,P04062 6 +Impaired vibratory sensation 0.4462558014428593 1.761355071479667 0.078178324344339 1.0 0.6239178902498214 31 O95140,O43819,Q6PI48,Q96RR1,Q9Y6B6,Q9Y619,Q96RL7,O00400,O94905,P00846,Q06787,O14773,O00165 13 +Generalized myoclonic seizure 0.4178782116632448 1.7598971085806527 0.078425253674909 1.0 0.62479243251692 39 Q9Y5U9,P03886,Q86SQ9,P16278,P07602,Q9NZJ7,Q96N66,Q9Y619,P04062,P00846,Q13510 11 +Myoclonic seizure 0.397926617082691 1.7542617202736022 0.0793856717735097 1.0 0.629138363933268 55 Q9Y5U9,P03886,Q86SQ9,P16278,P07602,Q9NZJ7,Q96N66,Q9Y619,P04062,P00846,Q13510,Q5XKP0,O75503 13 +Absent sternal ossification 0.9473337722185606 1.7489839579478736 0.0802937924263882 1.0 0.6319315947191004 2 Q9Y619 1 +Cardiac conduction abnormality 0.4414498711040713 1.746270932640504 0.0807638842638083 1.0 0.6345335224802489 32 O75306,P03886,P06280,Q9HD47,P0DP25,P23786,P46976,P50402,P00846 9 +Coronal craniosynostosis 0.6918747037723989 1.7434209510616958 0.0812601112564768 1.0 0.6362345027637056 6 Q6NUK1,P07237,P16435 3 +Bilateral tonic clonic seizure with generalized onset 0.6084094513178196 1.738780335125058 0.082073408883009 1.0 0.6389895674886414 10 Q13510 1 +Abnormal aortic valve morphology 0.4195662077406517 1.7381254259599546 0.0821887156391036 1.0 0.6389895674886414 38 Q9UHX1,P51812,P06280,Q96L58,Q9BUB7,Q9Y4P3,Q6NUK1,P04062,P21964,O75844 10 +Abnormal pelvis bone morphology 0.9427254772876894 1.7294921178782563 0.0837210559837871 1.0 0.6412027623019859 2 Q08AM6 1 +Retinal detachment 0.5440139445696985 1.729227076683783 0.0837684621168373 1.0 0.6412027623019859 13 O43505,Q13045,P49327,P04439,Q9BV10,Q8NCH0 6 +Corneal dystrophy 0.8593747424488454 1.729121682886653 0.0837873192340583 1.0 0.6412027623019859 4 P12235,P06280 2 +Visual field defect 0.4060396237113755 1.723203568061456 0.0848517187315389 1.0 0.6412027623019859 41 Q9H061,O75306,P03886,P40855,Q9H6K4,O60220,O60313,Q969G3,P04439,O00429,P00846,Q9Y5Y5,O75381 13 +Bilateral sensorineural hearing impairment 0.4797067337791131 1.7180847163082595 0.0857811641479338 1.0 0.6448565277881568 22 P03886,P07602,Q9NZJ7,Q96RR1,Q15067,Q13217,P38159,P55011,P35637 9 +Retinal telangiectasia 0.7305087906490353 1.7174046306625432 0.0859052661770989 1.0 0.6448565277881568 5 P03886,P00846 2 +Scrotal hypoplasia 0.5006996894404561 1.7151827129553257 0.0863117332798617 1.0 0.646840320741501 18 Q9Y5U9,Q6NUK1,Q9BV10,P16435 4 +Inverted nipples 0.6856999661617457 1.7135196621546602 0.0866169792466224 1.0 0.648060260843562 6 Q15067,Q9BV10,O60762 3 +Abnormality of the tongue 0.3527381574509991 1.7121605991414328 0.0868670762659848 1.0 0.6488642527651318 87 P10253,Q10713,Q9BTW9,Q08AM6,Q96A33,P51114,P16278,Q969G3,P04350,O75648,P49327,Q96RL7,Q6NUK1,Q13510,P21912,O75844,Q16637,O75381,O43924,P04066,O00754,O75431,Q9Y4P3,P61978,O94905,O15460,Q7LGA3,P40855,Q96S52,Q05655,P50542,Q9Y5Y5,O95831,Q15042 34 +Personality changes 0.516729871213063 1.705196997450222 0.0881576898255032 1.0 0.6519464235882341 16 P04062,P03886,O60220,Q9NR50 4 +Progressive neurologic deterioration 0.4890142733109835 1.704492645536566 0.0882890888737293 1.0 0.6519464235882341 20 Q9NPL8,P16278,P07602,Q9NZJ7,P04062,Q10713,Q5XKP0,P54802 8 +Abnormal heart valve morphology 0.3652706163320612 1.7037448859597335 0.0884287584987815 1.0 0.6519464235882341 73 Q9UHX1,Q5H8A4,Q96L58,P55795,Q9BUB7,O43909,P08236,P06280,P16278,P53701,Q6NUK1,Q96PU5,P04062,Q8NCH0,O75844,Q6ZXV5,Q9Y4P3,P21964,P37268,P51812,O95202 21 +Multiple glomerular cysts 0.9361421988150006 1.701622817913461 0.0888260972679182 1.0 0.6519464235882341 2 P00846 1 +Retinal arterial tortuosity 0.9361421988150006 1.701622817913461 0.0888260972679182 1.0 0.6519464235882341 2 P00846 1 +Leber optic atrophy 0.9361421988150006 1.701622817913461 0.0888260972679182 1.0 0.6519464235882341 2 P00846 1 +Low plasma citrulline 0.9361421988150006 1.701622817913461 0.0888260972679182 1.0 0.6519464235882341 2 P00846 1 +Fatigue 0.3722382255345667 1.6957588645438566 0.0899315556500419 1.0 0.6519464235882341 69 P07602,Q9NZJ7,Q07021,Q92804,P35637,P06280,Q9UHD9,Q53H12,Q96RR1,P12235,P04062,P21912,Q70HW3,Q4J6C6,P50416,O60313,Q15165,O00429,Q9NZ08,Q9NP80,Q14739,Q13423 22 +Cytochrome c oxidase negative muscle fibers 0.6639731294824938 1.6943917546582965 0.0901908652873746 1.0 0.6519464235882341 7 Q9Y2R0 1 +Retinal coloboma 0.6580182668270584 1.693873368110575 0.0902893486174076 1.0 0.6519464235882341 8 Q9UHX1,Q92620,Q10713,O14936,Q15042 5 +Poor head control 0.3641963202848507 1.6900217945205798 0.0910237851318624 1.0 0.6541345948891667 73 Q9P0J0,P03886,Q86SQ9,Q86Y39,P07602,Q96CU9,Q9NZJ7,O96000,P17900,Q5XKP0,O43676,Q10713,P06865,P00374,P13073 15 +Abnormal speech prosody 0.6568411696805043 1.6879077536214404 0.0914289380215849 1.0 0.654808176805374 8 P04062,P00846 2 +Very long chain fatty acid accumulation 0.7234954773779814 1.6854031381894945 0.0919108185969987 1.0 0.654808176805374 5 O75381,P40855,Q9Y5Y5 3 +Thoracic scoliosis 0.5584588983490171 1.6851461159509786 0.0919603841442466 1.0 0.654808176805374 12 Q9UHX1 1 +Cognitive impairment 0.396103754738407 1.6850131296992237 0.0919860383553496 1.0 0.654808176805374 166 O43464,Q6DKK2,Q13057,Q86SQ9,O60220,Q99720,P07602,Q9Y2R0,Q9BQE5,Q9NZJ7,P36543,P54802,Q9H2C2,Q14108,P57740,Q10713,P00846,O43826,P50897,P61916,P35637,O95140,P06280,P16278,Q9UHD9,Q9H6K4,O95470,Q96RR1,P17900,P12235,Q969G3,P04350,Q96RL7,P04062,Q13510,P21912,Q13217,O75381,O75503,O43681,P03886,O76024,O60313,Q9Y619,P10644,Q15031,O00429,P42345,P21964,Q9NZ08,Q9Y487,O75569,P22626,O75306,Q03164,Q9NPL8,P40855,Q9UJS0,Q6PI48,Q9NR50,P49770,Q06787,O96008,P04080,Q9NQZ5,P50542,Q9UBB4,P06865,O95831,Q5XKP0,Q9Y5Y5,P05067,O15118 73 +Delayed cranial suture closure 0.4433026840699701 1.6848501215434055 0.092017491897133 1.0 0.654808176805374 29 P51812,P40855,O75844,P16435,Q8NCH0,Q9Y487 6 +Abnormal arterial physiology 0.4450867979118665 1.6772820240672186 0.0934873460001193 1.0 0.6558678118801052 28 P06280,Q9Y4P3,Q14739,Q9NZ08,O75844,P05067 6 +Hypoplasia of the iris 0.721236086697195 1.675075826439674 0.0939193552076691 1.0 0.6558678118801052 5 O95202,Q7LGA3 2 +Retinal arteriolar tortuosity 0.5970413702985031 1.6743934722225744 0.0940532948827277 1.0 0.6558678118801052 10 P00846,P21964 2 +Renal hypoplasia 0.4420794549739842 1.6742206418224126 0.0940872441529041 1.0 0.6558678118801052 29 O43924,Q9UHX1,P21964,Q96I36 4 +Underdeveloped supraorbital ridges 0.5564125764288257 1.6724898970593922 0.0944277584239898 1.0 0.6568071453680886 12 P40855,P16435,Q6NUK1,Q9Y5Y5,P50542,Q6PGP7,O75381 7 +Thoracic kyphosis 0.5118125914570295 1.6711929807163013 0.0946835662688676 1.0 0.6575809816138609 16 Q9UHX1,P04062,O43909,P51648,P08236 5 +Poor eye contact 0.4084800577909996 1.667194896070541 0.0954756572987238 1.0 0.6620712881888642 39 Q15907,Q9UHX1,P03886,Q96CU9,Q86Y39,O96000,O43676,Q5XKP0 8 +Atlantoaxial abnormality 0.8435600508544814 1.6639230421282138 0.096127809620484 1.0 0.6655790045107792 4 Q9NWM8,Q8NCH0 2 +Centrocecal scotoma 0.8425559947299162 1.6597743056041825 0.0969598645987048 1.0 0.6682166993632126 4 O60313,P03886,P00846 3 +Abnormal corneal epithelium morphology 0.5181296997784492 1.6592459659069585 0.0970662385964777 1.0 0.6682166993632126 15 Q9NZ08,O75844,P51648 3 +Erlenmeyer flask deformity of the femurs 0.8420395954969209 1.6576401360064614 0.0973901234728094 1.0 0.6682166993632126 4 Q9NZJ7,P04062 2 +Abnormal pleura morphology 0.4771812524331968 1.6555247197321716 0.097818106352703 1.0 0.670004866719008 21 Q6NUK1,Q14739,Q8NCH0,Q9NZ08,P08236 5 +Coxa valga 0.4822916385711793 1.6540106372301338 0.098125351423022 1.0 0.670004866719008 20 Q96A33,P51812,Q96L58,P16278,P04066,O00754,Q9Y619,O43909,O75844,Q9H9E3 10 +Frequent falls 0.4106955763144001 1.651720580192746 0.0985915252896909 1.0 0.670004866719008 38 Q9NZJ7,P12235,P04062,Q13510,P00846 5 +Progressive gait ataxia 0.5930389593235724 1.6516267682328274 0.098610659694954 1.0 0.670004866719008 10 P07602,Q9NZJ7,P00846 3 +Temperature instability 0.6554167443678381 1.6514950505862451 0.0986375305574347 1.0 0.670004866719008 7 Q9NZJ7,Q9HC21 2 +Heparan sulfate excretion in urine 0.8404967922242453 1.6512623657686192 0.0986850133629384 1.0 0.670004866719008 4 P15586,P08236 2 +Abnormal left ventricle morphology 0.4529423171390961 1.648231523232348 0.0993051704055527 1.0 0.6709188371800943 25 P03886,P06280,P21912,Q96RR1,P12235,Q07021,Q6NUK1,P10253,O60566,P40939,O75880,Q15645 12 +Neurofibrillary tangles 0.8392621870882808 1.6461568418106376 0.0997314721885791 1.0 0.6709188371800943 4 P61916,P05067,O15118 3 +Recurrent bronchitis 0.8384983170430542 1.6429971729443478 0.100383518182193 1.0 0.6715362120747002 4 Q03518,Q05655 2 +Abnormal circulating follicle stimulating hormone concentration 0.6706820939864993 1.6404593750879302 0.1009096886469556 1.0 0.6740648658663745 6 P16435,Q969G3,Q8IY37,P16870 4 +Titubation 0.6469393151997521 1.6375896569624142 0.1015073221134694 1.0 0.6764308955913865 8 Q99720,Q5JRX3 2 +Stillbirth 0.5503951212857721 1.6351830568389392 0.1020106788774544 1.0 0.6764308955913865 12 O75844,Q86WC4,Q14739,P16435 4 +Gastrointestinal hemorrhage 0.4448969277887279 1.633914912547121 0.102276718030813 1.0 0.6764308955913865 26 Q9UHX1,Q9UGP8,O76024,P16930,Q14739,P21964,P21912,Q9NZ08 8 +Metaphyseal striations 0.7120367584664886 1.6329400628689104 0.102481603127396 1.0 0.6764308955913865 5 Q9UG56 1 +Abnormality of lipoprotein cholesterol concentration 0.5287337083113078 1.630251863284132 0.1030482766860476 1.0 0.6764308955913865 13 Q9UJS0,Q9Y6B6,Q15800,Q8N511,P50402,Q10471,P37268 7 +Hyperlipidemia 0.4366078885963796 1.626546407446372 0.1038334694788454 1.0 0.6777916571152603 29 P50416,P06280,Q9UJS0,O95470,P28070,P23786,Q9BTV4,O75431,Q13045,O43826,P50402,O75844 12 +Premature rupture of membranes 0.6671989487376231 1.6234482435494682 0.104493618812967 1.0 0.6780905449075422 6 O75844 1 +Neck muscle weakness 0.5111149448435997 1.6115952126849706 0.1070500531307734 1.0 0.6885763757587456 15 P07602,Q99720,Q9NZJ7,P46976,P35637 5 +Abnormal metacarpal morphology 0.4315721138786277 1.605921572932518 0.1082911428972954 1.0 0.6886539503315339 30 Q08AM6,O43924,P51812,Q96L58,P16278,Q9NX62,P16435,Q96S52,P10644,O43909,Q14739,Q9H9E3,P08236 13 +Hyperesthesia 0.9134298880842616 1.6052928798803412 0.1084293653736905 1.0 0.6886539503315339 2 Q9NZJ7 1 +Bilateral tonic clonic seizure with focal onset 0.9134298880842616 1.6052928798803412 0.1084293653736905 1.0 0.6886539503315339 2 Q9NZJ7 1 +Abducens palsy 0.9134298880842616 1.6052928798803412 0.1084293653736905 1.0 0.6886539503315339 2 Q9NZJ7 1 +Ophthalmoparesis 0.3648923005357482 1.604773726049065 0.1085436101094108 1.0 0.6886539503315339 69 Q86SQ9,Q92620,Q07021,Q10713,Q7KZN9,P00846,P51530,Q9P0J0,Q9GZY8,Q96RR1,P12235,Q969G3,P04062,P21912,P03886,O76024,O60313,O00429,O75306,Q96CU9 20 +Abnormality of the gastric mucosa 0.5092885918897219 1.5991543724976935 0.1097863057594332 1.0 0.6927581985358675 15 Q14739,Q05655,P04062,Q9Y4P3 4 +Vascular tortuosity 0.9364504445176124 1.5984829022545763 0.1099355475669736 1.0 0.6927581985358675 3 P05067,P00846 2 +Profound global developmental delay 0.5238482344348607 1.5984091493998842 0.1099519497346441 1.0 0.6927581985358675 13 P40855,Q9GZY8,O60313,P55011,Q9Y5Y5,P37268,O75381 7 +Intestinal malrotation 0.4527497866963062 1.5968509286822594 0.1102989403787204 1.0 0.693983236214107 24 Q14739,Q9BV10,P21964,Q8NCH0 4 +Abnormality of krebs cycle metabolism 0.7033783676894481 1.59315840688399 0.1111246593582921 1.0 0.6943202567873269 5 P00846 1 +Increased serum lactate 0.3578307611157482 1.5925183047000977 0.1112682935146101 1.0 0.6943202567873269 107 Q86Y39,Q6P4A7,Q9BUB7,Q07021,P00846,Q7KZN9,Q00325,O75880,Q9P0J0,O14949,Q96RR1,Q53H12,P12235,O60783,P21912,Q96I36,Q9BW92,P13073,Q9NVI7,Q9UBX3,Q70HW3,Q99797,P03886,Q5T2R2,Q9Y584,Q3ZCQ8,O00429,Q5JRX3,O75306,Q96CU9,Q9BWD1,Q9NP80,Q5XKP0 33 +Abnormal protein glycosylation 0.5002712136035475 1.5909508908896846 0.1116206282142411 1.0 0.6955647092418944 16 Q9H0U3,P51571,O60762,Q8N511,Q10471,Q9BT22,Q9Y487,Q9H9E3 8 +Agenesis of cerebellar vermis 0.9091507570770244 1.5871187637481656 0.1124857489332247 1.0 0.6990405353787421 2 O43924 1 +Raynaud phenomenon 0.6595716205300959 1.5861139134208302 0.1127134712299191 1.0 0.6995001099930452 6 O75844 1 +Intracellular accumulation of autofluorescent lipopigment storage material 0.9071757735352208 1.57872867410674 0.1143983048393717 1.0 0.7003607473288511 2 O75503 1 +Focal t2 hyperintense brainstem lesion 0.4814914437788617 1.5752265407244994 0.1152041630579967 1.0 0.7003607473288511 18 O75306,P03886,Q96CU9,Q86Y39,O96000,O43676 6 +Axial dystonia 0.905859117840678 1.5731346289331285 0.1156876480720003 1.0 0.7003607473288511 2 Q99720 1 +Short middle phalanx of finger 0.8214984543959816 1.5725280001136566 0.1158281507574274 1.0 0.7003607473288511 4 Q9UHX1 1 +Aplasia hypoplasia involving bones of the thorax 0.4221368003003923 1.57197508596213 0.1159563292745018 1.0 0.7003607473288511 32 Q08AM6,Q9UHX1,Q9Y619,Q14739,Q9BV10,O75844 6 +Abnormal talus morphology 0.4893905566230531 1.5714192639612583 0.1160852942374046 1.0 0.7003607473288511 17 Q08AM6,Q9UHX1,O75844 3 +Abnormal visual fixation 0.6561277313974989 1.5692199623929537 0.1165966943172649 1.0 0.7009780152072789 6 Q13510 1 +Abnormal pulmonary interstitial morphology 0.4349533478601268 1.569087143695961 0.1166276350098494 1.0 0.7009780152072789 27 Q8IZA0,P09601,Q14108,Q05655,P04062,Q13510 6 +Abnormality of lysosomal metabolism 0.6977122798056802 1.5670630801730372 0.1170999478357583 1.0 0.7021064064950381 5 Q9NZJ7,Q13510 2 +Aplasia hypoplasia of toe 0.4215750912860808 1.5668645575920552 0.1171463536007328 1.0 0.7021064064950381 32 Q08AM6,Q9UHX1,Q5H8A4,Q13510,Q7LGA3 5 +Abnormal thoracic spine morphology 0.4343575678440132 1.5639746670224506 0.1178235178020117 1.0 0.7050479119191003 27 P51648,Q9UHX1,O75844,P04062 4 +Abnormal size of the clitoris 0.475152135024141 1.5630721785751147 0.1180356186456155 1.0 0.7050479119191003 19 Q08AM6,P40855,P53701,P16435,Q9Y619,O75381 6 +High frequency sensorineural hearing impairment 0.8191543418641773 1.5627895102036105 0.1181021123065189 1.0 0.7050479119191003 4 O75844,Q13510 2 +Aspiration pneumonia 0.4482183646622517 1.5599237071334082 0.1187779113799933 1.0 0.7052581781902095 24 P16278,O60220,Q969G3,Q6NUK1,P04062,Q13510 6 +Sensory neuropathy 0.4082354432458735 1.5593746827650548 0.1189077248646746 1.0 0.7052581781902095 36 P03886,P22626,O60220,O60313,Q96RR1,O15270,Q15067,Q96RL7,O15269,P40939,P00846,O94905,O95831,Q15041,Q8IV08 15 +Severe global developmental delay 0.362769452438299 1.5573632226589529 0.1193842727205325 1.0 0.7052581781902095 68 Q5H8A4,Q13409,Q9HC21,O00584,O43909,Q9BV10,O60566,P00846,Q9BT22,Q96A33,O75381,P03886,P00387,Q15067,Q7LGA3,P51812,P40855,O60762,Q96S52,Q9Y5Y5 20 +Varicose veins 0.8170130113041326 1.5538891990607302 0.1202108485386763 1.0 0.7052581781902095 4 P21964 1 +Venous insufficiency 0.8170130113041326 1.5538891990607302 0.1202108485386763 1.0 0.7052581781902095 4 P21964 1 +Abnormality of the umbilical cord 0.6528997402513967 1.5533648480028104 0.1203359958604213 1.0 0.7052581781902095 6 O75844 1 +Aortic valve stenosis 0.603525836646702 1.5524549740254965 0.1205533983016082 1.0 0.7052581781902095 9 O75844,P04062 2 +Ventricular hypertrophy 0.4106004537586657 1.5505177433216528 0.1210172981415877 1.0 0.7052581781902095 35 P03886,P06280,Q96RR1,P23786,P12235,Q07021,P46976,Q6NUK1,P10253,Q9BV10,O75880,O75844 12 +Prominent nasolabial fold 0.6520369367873216 1.5491236942398334 0.1213519880413369 1.0 0.7052581781902095 6 Q8NCH0 1 +Abnormality of the nasolabial region 0.6520369367873216 1.5491236942398334 0.1213519880413369 1.0 0.7052581781902095 6 Q8NCH0 1 +Stroke like episode 0.6936521085652811 1.5483348279018505 0.1215417033211982 1.0 0.7052581781902095 5 P03886 1 +Osteopetrosis 0.8148645618902247 1.5449552925223222 0.1223570776900455 1.0 0.7052581781902095 4 Q86WC4 1 +Abnormality of the tarsal bones 0.4570567673716639 1.541099116749778 0.1232926648069097 1.0 0.7052581781902095 22 Q08AM6,Q9UHX1,O75844,Q14739 4 +Decreased absent ankle reflexes 0.5139317661745507 1.5334913443992035 0.125154837693441 1.0 0.7052581781902095 13 O95140,P07196,Q9H6K4,O60313,Q96RR1,P12235,Q96RL7,Q15041 8 +Blurred vision 0.6903479105844836 1.53307629788606 0.1252570569022038 1.0 0.7052581781902095 5 O75306,P03886,P00846 3 +Slender long bone 0.4992974926896119 1.5308504801199612 0.125806350274843 1.0 0.7052581781902095 15 Q9Y619,Q08AM6,Q9Y487,Q96L58 4 +Abnormal social behavior 0.3637917524056657 1.5305802439745078 0.1258731674446915 1.0 0.7052581781902095 66 Q15907,Q9UHX1,Q86Y39,P07602,Q9NZJ7,O96000,O43909,Q9P0J0,Q9GZY8,P03886,Q9Y4P3,Q15067,O43676,O75306,Q9NPL8,Q96CU9,O96008,Q5XKP0,P05067 19 +Broad palm 0.6897481536949301 1.5303050322364835 0.1259412432640894 1.0 0.7052581781902095 5 P51812,Q14739,P10644 3 +Motor neuron atrophy 0.4554034723926612 1.528070742419442 0.1264949747183865 1.0 0.7053505670985114 22 Q9UHD9,Q99720,Q15165,Q13510,Q92804,P22626,P35637 7 +Fatigable weakness of swallowing muscles 0.5130351838568896 1.527603591391387 0.1266109895522578 1.0 0.7053505670985114 13 Q92804,Q15165,P35637 3 +Long toe 0.5981043388785295 1.5230258217190258 0.1277522453545643 1.0 0.7087133708755037 9 Q9UHX1,P23786,P10644,Q9P2J5 4 +Talipes equinovarus 0.3530172681030641 1.52224722888692 0.1279471452198985 1.0 0.708894016594868 72 Q15907,Q5H8A4,Q96A33,Q9HC21,P55201,P16435,Q9Y619,Q9BV10,Q15392,Q8NCH0,P21964,Q9Y487,Q9NWM8,P08236 14 +Acne 0.5703518068091433 1.521651290022716 0.1280964787076239 1.0 0.708894016594868 10 Q9NZ08,P21964 2 +Abnormal glycosylation 0.4642475467092065 1.5173526318465045 0.1291776764771186 1.0 0.7112247348129148 20 Q9H0U3,P51571,O60762,Q8N511,Q10471,Q9BT22,Q9Y487,Q9H9E3,P46977 9 +Thickened ribs 0.8076416337285995 1.514891911019468 0.1297997791880076 1.0 0.7112247348129148 4 P16278,P15586,P54802 3 +Dyschromatopsia 0.6280398337890228 1.5131522385318377 0.1302409929759311 1.0 0.7112247348129148 7 Q9H061,O60313,Q9H6K4 3 +Abnormal palmar dermatoglyphics 0.3760203612912332 1.5100280790419929 0.1310362595156702 1.0 0.7112247348129148 55 Q15907,Q9UHX1,O43909,Q08AM6,Q9NXE4,Q6NUK1,Q8NCH0,Q96I36,O75381,O96028,O75431,P61978,P42345,Q9Y487,P51812,P40855,O95202,Q96S52,Q9Y5Y5,P50542,Q9H4L7 21 +Short femur 0.6438286737316075 1.5087082755009342 0.1313733497879732 1.0 0.7112247348129148 6 Q9UHX1 1 +Aplasia hypoplasia of the 5th finger 0.53014215802258 1.5086681418130643 0.1313836108328059 1.0 0.7112247348129148 12 Q9UHX1 1 +Osteoarthritis 0.5953245540217644 1.5079079344163049 0.1315780916557718 1.0 0.7112247348129148 9 Q14108,O75844,P04062 3 +Macroglossia 0.4149718357561316 1.5066192397113196 0.1319082829293336 1.0 0.7112247348129148 32 Q96A33,P16278,P04066,O00754,Q9Y4P3,P10253,Q10713,O94905,P21912,Q7LGA3 10 +Visual loss 0.3826805301690444 1.5061416109487364 0.1320308246378769 1.0 0.7112247348129148 46 O75306,P03886,O60220,P07602,P50897,Q9NZJ7,P53701,O60313,Q969G3,O00429,Q10713,P00846,O14773,O75503 14 +Nonprogressive 0.6415944222924932 1.497686819075249 0.1342146380040394 1.0 0.7162951042965024 6 Q9NQZ5 1 +Perseveration 0.6248476931484173 1.4969195458838822 0.1344141936625287 1.0 0.7162951042965024 7 P35637 1 +Mitral stenosis 0.8032802985932386 1.4967191001710156 0.134466364207229 1.0 0.7162951042965024 4 O75844 1 +Neoplasm of the tongue 0.6821019125751882 1.494931783728147 0.1349322462689555 1.0 0.7170739466055213 5 O43924,Q05655,Q969G3 3 +Exaggerated startle response 0.6189907772397102 1.494320956167085 0.1350917503277493 1.0 0.7170739466055213 8 P17900,P06865 2 +Extramedullary hematopoiesis 0.6809961708128661 1.4898100001657455 0.1362742009651314 1.0 0.7210854639723617 5 Q86WC4 1 +Atrophy degeneration involving the caudate nucleus 0.639913181895486 1.4893877016701669 0.1363853051860035 1.0 0.7210854639723617 6 P00846 1 +Echolalia 0.6230731966033721 1.4878872006279054 0.1367806436980609 1.0 0.7210854639723617 7 Q9UHX1,P53701 2 +Cerebral dysmyelination 0.6392320128902307 1.4860238804928867 0.1372728045643385 1.0 0.722448956472775 6 Q9NZJ7 1 +Spastic paraparesis 0.460077309537923 1.4855392258554478 0.1374010404977232 1.0 0.722448956472775 20 Q9Y619,Q5XKP0,P04062,Q9H6K4 4 +Endocarditis 0.6385999134453618 1.4829016824695525 0.1381005343777723 1.0 0.7237549894982563 6 Q9NZ08 1 +Abnormal pericardium morphology 0.5905136027420361 1.4816987892000646 0.1384204594172444 1.0 0.7245968583303165 9 Q9NZ08,P04062 2 +Orthostatic hypotension due to autonomic dysfunction 0.5901541256328042 1.4797381829420313 0.1389431314822171 1.0 0.7256628072475383 9 Q9NZJ7,P04062 2 +Fatigable weakness of bulbar muscles 0.4914961058984772 1.4772365926515345 0.1396122280548788 1.0 0.7276498210679937 15 Q92804,Q15165,P35637 3 +Aplasia hypoplasia of the nipples 0.5053658534751798 1.4771198902741969 0.1396435027022111 1.0 0.7276498210679937 13 Q96A33,Q08AM6,Q5H8A4,Q6NUK1 4 +Macrovesicular hepatic steatosis 0.6202498075445915 1.4735033546323244 0.1406153599589372 1.0 0.7281334086237621 7 Q5XKP0 1 +Abnormal gallbladder morphology 0.4236863439306194 1.4720286797901705 0.1410131330346011 1.0 0.7281334086237621 27 Q96A33,P40855,Q9NZJ7,Q9Y4P3,P04062,P21964 6 +Brittle hair 0.4977598389298694 1.4715378099846537 0.1411457300580427 1.0 0.7281334086237621 14 Q9Y487,O75844 2 +Coarse hair 0.4754454427274962 1.471175710007256 0.1412436043236078 1.0 0.7281334086237621 17 Q96A33,P51812,Q6NUK1,Q9Y487,P15586 5 +Avascular necrosis 0.4529849518772901 1.4686896534795653 0.1419169850682302 1.0 0.7281334086237621 21 Q9NZ08,Q9Y619,O75844,P04062 4 +Abnormal mitochondrial morphology 0.504061347913896 1.4685119436052734 0.1419652143719327 1.0 0.7281334086237621 13 Q9GZY8,O60783,P46976,P51530,P35637 5 +Abnormal metatarsal morphology 0.4478618400951764 1.468461968398423 0.1419787795855946 1.0 0.7281334086237621 22 O43505,Q08AM6,Q96L58,O96028,O95202,P16435,Q96S52,P10644,Q15392,Q9H9E3,P08236 11 +Decerebrate rigidity 0.7961311493505642 1.4669000040126543 0.1424032594435578 1.0 0.7281334086237621 4 P07602,Q9NZJ7 2 +Redundant neck skin 0.6136532917800815 1.4667639801591554 0.1424402713947421 1.0 0.7281334086237621 8 Q08AM6,Q9Y487 2 +Respiratory failure 0.3570469532433067 1.466689005483035 0.1424606750843993 1.0 0.7281334086237621 67 P07602,Q9NZJ7,P23786,Q9BUB7,P10253,Q92804,Q9BT22,P61916,Q9BTW9,P35637,Q9UHD9,P53701,Q13510,Q70HW3,Q15165,Q9Y619,Q86WC4,O75306,Q5XKP0 19 +Acetabular dysplasia 0.5606091543600029 1.46537547468085 0.1428185049096089 1.0 0.7281334086237621 10 P08236,Q9Y584,P16278,Q96L58 4 +Abnormality of epiphysis morphology 0.3718953644102679 1.4634570648633038 0.1433423537756353 1.0 0.7281334086237621 55 Q96L58,Q6NUQ1,Q9UG56,O43909,Q5JRA6,P08236,P16278,P16435,O75381,Q15125,O96028,Q9Y619,P10644,Q9H9E3,Q7LGA3,Q9HC07,P51812,P38435,P40855,Q96HY6,O00116,O95202,Q14739,Q9Y5Y5,P50542,O95831 26 +Abnormality of the 5th toe 0.634493115837389 1.4626004138879358 0.1435767499434064 1.0 0.7281334086237621 6 O43924,Q14739,Q10713 3 +Postaxial foot polydactyly 0.634493115837389 1.4626004138879358 0.1435767499434064 1.0 0.7281334086237621 6 O43924,Q14739,Q10713 3 +Gait ataxia 0.3610473840688984 1.461484631958579 0.1438824900013195 1.0 0.7281334086237621 64 Q15907,Q5H8A4,P03886,P07602,Q9NZJ7,P12235,Q14108,Q10713,P00846,Q8IV08,O15118 11 +Photophobia 0.4042646609367747 1.461296203804232 0.1439341712211375 1.0 0.7281334086237621 34 Q9NZ08,Q86SQ9,O60220,P07602,Q9NZJ7,Q92620,P04080,Q15555,P04439,Q96S66,P51648 11 +Upper airway obstruction 0.7947300047460881 1.4610517284215654 0.1440012460329054 1.0 0.7281334086237621 4 O75844,P16435 2 +Limb girdle muscle weakness 0.4304582019622809 1.4610314483857991 0.1440068111850738 1.0 0.7281334086237621 25 P07602,O60313,Q9NZJ7,P12235,P46976,Q13126,O14979,P51530 8 +Supraventricular arrhythmia 0.4740148186623453 1.4608447580052042 0.1440580496287944 1.0 0.7281334086237621 17 P00846,Q9HD47 2 +Aplasia hypoplasia of the sternum 0.6740781781482802 1.457731171520417 0.1449146564025178 1.0 0.72995547634028 5 Q9Y619,Q08AM6 2 +Increased csf lactate 0.3748497657352519 1.457469479034214 0.1449868303681512 1.0 0.72995547634028 51 P03886,Q9HC21,Q96CU9,Q86Y39,O96000,O43676,P00846,Q7KZN9,Q96I36,P13073 10 +Abnormal neuron morphology 0.4195224073832582 1.455460589426684 0.1455417931502822 1.0 0.72995547634028 28 Q9UHD9,Q99720,Q15165,Q13510,Q92804,Q16637,P22626,P35637 8 +Short nail 0.6328883573711147 1.4546601026787689 0.145763383044339 1.0 0.7302617064633239 6 Q9Y487,O75844 2 +Exercise intolerance 0.4116928451987849 1.4518275101156428 0.1465495725855909 1.0 0.7333927455355922 31 P03886,Q9Y2R0,P23786,P12235,Q07021,Q9H2D1,P51530 7 +Abnormal morphology of the conjunctival vasculature 0.6317161429927435 1.448857415287314 0.1473774057016483 1.0 0.7349068922221288 6 P04066,P06280,P10619 3 +Duplication involving bones of the feet 0.4796072175100093 1.4458503254587796 0.1482191872211129 1.0 0.7363496713146247 16 O43924,Q15125,O95202,Q14739,Q10713,O43909,P21964 7 +Purpura 0.4792994287102744 1.443675969802377 0.1488301440100987 1.0 0.7375036221154022 16 P38435,P04062,Q8NCH0,P21964 4 +Lower limb hypertonia 0.556748037255345 1.4430008899431532 0.1490202205343298 1.0 0.7376419839071452 10 O00400 1 +Abnormalities of placenta or umbilical cord 0.4998300885686929 1.4405506520495883 0.1497116703867824 1.0 0.7378530753948791 13 P04637,P16278,O60826,O43175,P16435,Q6PGP7,Q9H4L7,O75844 8 +Abnormality of circulating adrenocorticotropin level 0.6700998193045029 1.4392574447543292 0.1500775950869277 1.0 0.7380473134994587 5 Q13423,Q969G3,P16435 3 +Asymmetric septal hypertrophy 0.8742593811718162 1.4387960704902476 0.1502083100657367 1.0 0.7380473134994587 2 P15586 1 +Pleural effusion 0.556005244701038 1.4386919779368612 0.1502378132118045 1.0 0.7380473134994587 10 Q9NZ08 1 +Fluctuations in consciousness 0.6125668933245016 1.434286762672761 0.151490446264588 1.0 0.7416077622045328 7 O43819,O75306,P03886,Q9UJS0,P04062 5 +Abnormal midbrain morphology 0.6122384965454395 1.432608096769324 0.1519698665600062 1.0 0.7416077622045328 7 O43924,P04062 2 +Abnormal protein o linked glycosylation 0.7878787878787833 1.4324374702581504 0.1520186614165486 1.0 0.7416077622045328 4 Q10471,Q9H9E3,Q8N511 3 +Abnormality of somatosensory evoked potentials 0.7877968098924452 1.4320949176154707 0.1521166587995743 1.0 0.7416077622045328 4 Q9NQZ5 1 +Retinopathy 0.4190446111330876 1.4318204508904904 0.1521952128775512 1.0 0.7416077622045328 27 Q9NZ08,O43819,Q5H8A4,O75306,Q9Y6B6,O96028,O95202,O60762,Q15555,P40939,P00846,P51648,Q5JRA6 13 +Flaring of rib cage 0.8722843976300201 1.4303998877195825 0.152602280470762 1.0 0.7416077622045328 2 P16278 1 +Abnormality of the radioulnar joints 0.8722843976300094 1.430399887719536 0.1526022804707754 1.0 0.7416077622045328 2 P16435 1 +Radioulnar dislocation 0.8722843976300094 1.430399887719536 0.1526022804707754 1.0 0.7416077622045328 2 P16435 1 +Atlantoaxial dislocation 0.8722843976300017 1.4303998877195032 0.1526022804707847 1.0 0.7416077622045328 2 Q8NCH0 1 +Paraplegia 0.3723391301295229 1.4297665861916804 0.1527840221417538 1.0 0.7416077622045328 51 Q9P0J0,O75306,Q96L58,Q96CU9,O60313,O00754,P56192,Q9Y619,O00400,P04062,O00429,Q7KZN9,P00846,O94905 14 +Submucous cleft of soft and hard palate 0.4479311436685552 1.4292969541958642 0.1529189010656961 1.0 0.7416077622045328 21 Q9Y619,O75844,Q7LGA3 3 +Pneumothorax 0.6267363614743672 1.4241826910968531 0.1543935940730971 1.0 0.7440004866933464 6 Q6NUK1,Q8NCH0 2 +Abnormal delivery 0.4517833387826659 1.4220262458619175 0.1550186318571038 1.0 0.7458462265796757 20 Q9Y619,O75844 2 +Lower limb pain 0.6260550972060162 1.4208041037329942 0.1553737173560945 1.0 0.7458462265796757 6 O95140,O75477,O75569,P00846 4 +Infantile axial hypotonia 0.5528481599099424 1.4203617796839556 0.1555023838148106 1.0 0.7458462265796757 10 Q9GZY8,P07602,P17900,Q9NZJ7,O43909 5 +Abnormal brainstem mri signal intensity 0.4513442566412731 1.4186552268618169 0.1559995564381495 1.0 0.7458462265796757 20 O75306,P03886,Q96CU9,Q86Y39,O96000,O43676 6 +Abnormality of the ribs 0.3657785440721831 1.4165905960812704 0.1566026595364649 1.0 0.7458462265796757 57 Q08AM6,Q9UHX1,Q5H8A4,Q96HY6,P16278,P16435,Q9Y619,P07237,Q14739,Q9BV10,O75844,P15586,P54802 13 +Posteriorly rotated ears 0.3424801847719207 1.4143104836346023 0.1572707601550307 1.0 0.746640756270823 103 O43505,Q9UHX1,Q5H8A4,Q96L58,P23786,O60566,Q15392,Q10713,Q15645,Q9NXE4,P16435,Q6NUK1,P04062,Q8NCH0,O75381,O43924,Q4J6C6,Q9Y4P3,P42892,Q9Y619,Q15555,Q10471,P37268,Q7LGA3,Q9HC07,P40855,O95202,Q96S52,Q9Y5Y5 29 +Progressive spastic quadriplegia 0.608573023360887 1.4138583671423706 0.1574034920342315 1.0 0.746640756270823 7 P17900,Q9NZJ7 2 +Abnormal atrioventricular conduction 0.4891300940951035 1.4132324613142055 0.1575873848877473 1.0 0.746734389431628 14 P06280,Q9HD47,P0DP25,P50402,P21912 5 +Focal segmental glomerulosclerosis 0.4457344292076114 1.4121373626685298 0.1579095193659057 1.0 0.7469457296751333 21 P03886,O95470,Q12769,Q8NFH4,O75431,Q14108,O43826,Q9BW27,Q8N1F7 9 +Abnormal mitochondria in muscle tissue 0.4457123268177073 1.411964598861347 0.1579603851280453 1.0 0.7469457296751333 21 O75306,P03886,Q96CU9,Q86Y39,O96000,O43676 6 +Abnormal upper motor neuron morphology 0.5510009455872455 1.4096248609305693 0.1586504821470675 1.0 0.7486525345300937 10 Q99720,P35637 2 +Abnormal auditory evoked potentials 0.5509021629748291 1.4090504435291642 0.1588202528404598 1.0 0.748677026084199 10 P07602,Q9NZJ7,O60220 3 +Corpus callosum atrophy 0.4739537238119602 1.405853967962032 0.1597674926631453 1.0 0.7500333582297712 16 Q8N766,O60313,O00754,P51572,Q9UNE7,O00429,Q9Y5Y5,Q9H9P8,O75503 9 +Action tremor 0.3692689007018507 1.404307441584676 0.1602273192802643 1.0 0.7506427141152652 52 P07602,Q99720,Q9NZJ7,Q9BUB7,Q14108,P00846,O14773,P35637,Q9H6K4,P04350,Q96RL7,O43681,P03886,Q5JRX3,O75569,O75306,P04080,O75027,Q9UBB4 19 +Tissue ischemia 0.4443063440892714 1.4009701931056369 0.1612229866225401 1.0 0.7533598248408542 21 Q9NZ08,P05067,O75844,Q9Y4P3 4 +Aplasia hypoplasia of the ribs 0.4489735310248075 1.4004396140884712 0.1613817143677982 1.0 0.7533598248408542 20 Q08AM6,Q9UHX1,Q96HY6,Q9Y619,Q14739,Q9BV10 6 +Distal sensory impairment of all modalities 0.661369033833003 1.3986539747558613 0.1619167722646493 1.0 0.7538990757747078 5 O95140,O15269,O15270 3 +Foam cells 0.660156405589614 1.3930082325323758 0.1636173012052579 1.0 0.7562361931254005 5 Q13510,P16278,O15118 3 +Mediastinal lymphadenopathy 0.6594209394632706 1.3895833493377143 0.16465543480277 1.0 0.7562361931254005 5 Q01844,Q05655,Q9H0U3 3 +Abnormal ldl cholesterol concentration 0.5108600888532919 1.3869510546294703 0.165456688209834 1.0 0.7578430626556684 12 Q9UJS0,Q9Y6B6,Q15800,Q8N511,P50402,P37268 6 +Calvarial skull defect 0.6191006897082451 1.3862765134695338 0.1656624856672035 1.0 0.7578430626556684 6 Q14739,Q5H8A4,O95202 3 +External ear malformation 0.4709697131298441 1.3846952511196673 0.1661456717967393 1.0 0.7587361741270051 16 Q9BXW9,P40855,Q15555,Q9Y5Y5,Q8NCH0,O75381 6 +Hypoglycemic seizures 0.5977309314442517 1.3842187458323802 0.166291485074659 1.0 0.7587361741270051 8 P31751,P40939,O43826,Q16836,Q13423 5 +Prominent superficial blood vessels 0.4912135764714221 1.383424405401757 0.1665347715641816 1.0 0.7590848455365353 13 Q9Y487,O75844 2 +Abnormal cardiac test 0.4705733867266103 1.3818825960055536 0.1670077526142794 1.0 0.7592687505564923 16 Q9HD47,P0DP25,Q96RR1,P12235,Q9BTV4,P46976,P10253,Q16836 8 +Abnormal muscle fiber morphology 0.3455068251879621 1.381660900547934 0.1670758450883818 1.0 0.7592687505564923 70 P03886,Q99720,O60313,O96008,P23786,P12235,P46976,O43676,O14979,Q9H2D1,P50402,P00846,P05067,Q70HW3,P22626,P35637 16 +Occipital meningocele 0.7755510341915277 1.380885448145299 0.1673141849114696 1.0 0.7595930410801152 4 P21964 1 +Abnormal diaphysis morphology 0.3581838389243874 1.3802977037551811 0.1674950016914549 1.0 0.7596557953085029 61 Q08AM6,Q9HC07,P51812,Q96HY6,P16278,Q9Y4P3,P16435,Q9Y619,Q13126,P07237,Q14739,Q9Y487,P08236,Q7LGA3 14 +Severe short stature 0.4310280933054562 1.3750531308993883 0.169114973422181 1.0 0.7616871426707937 23 Q96L58,P16278,Q96HY6,Q9Y619,P10619,Q15392 6 +Abnormality of the coagulation cascade 0.3823876054443247 1.3715217452831487 0.1702123695681301 1.0 0.7657712348327935 38 P38435,Q9UJS0,P51571,O60762,Q6NUQ1,Q9Y619,P10644,Q86WC4,O43826,Q9BV10,Q5XKP0,Q9Y487,Q16836,Q9H9E3,Q9P2J5 15 +Deep palmar crease 0.543928764641531 1.368439200297758 0.1711746410103507 1.0 0.7662003050616578 10 O75431,P61978,Q6NUK1,P42345,Q9Y487 5 +Aganglionic megacolon 0.488422321783185 1.3648675906160963 0.1722946701945733 1.0 0.7662003050616578 13 P42892,P21964 2 +Chronic diarrhea 0.4485956803664788 1.363284191739283 0.1727929621804393 1.0 0.7662003050616578 19 Q96A33,Q13277,Q13510,Q9BT22,Q9H9E3 5 +Abnormal rib cage morphology 0.3485406749523373 1.3610061055756664 0.1735117599823152 1.0 0.7662003050616578 67 Q08AM6,Q9UHX1,Q5H8A4,Q96HY6,P16278,P16435,Q9Y619,P07237,Q14739,Q9BV10,O75844,P15586,P08236,P54802 14 +Episodic respiratory distress 0.8757921529602737 1.360825688528528 0.1735687817856068 1.0 0.7662003050616578 3 P00846 1 +Abnormality of the gallbladder 0.3959573998164784 1.3563472332389517 0.1749887137439878 1.0 0.769104984368503 33 Q96A33,Q5H8A4,P40855,Q9NZJ7,Q9Y4P3,P04062,P21964 7 +Abnormal labia majora morphology 0.5238878102825135 1.3539733028321577 0.1757448952447446 1.0 0.7694547915960958 11 Q9Y619,Q08AM6,P16435 3 +Hypoplastic labia majora 0.5238878102825135 1.3539733028321577 0.1757448952447446 1.0 0.7694547915960958 11 Q9Y619,Q08AM6,P16435 3 +Ovoid vertebral bodies 0.5964915634535595 1.3518992489742605 0.176407547843747 1.0 0.7701220625969445 7 P15586,P16278,P54802 3 +Primary gonadal insufficiency 0.5910839015637825 1.3496190826426029 0.1771381998799395 1.0 0.7701220625969445 8 Q8IY37,P49770,O76024,Q9NR50 4 +Sensorimotor neuropathy 0.4004241388827059 1.3491692704938656 0.1772826026458465 1.0 0.7701220625969445 31 P03886,P07602,O60313,Q9NZJ7,Q9Y2R0,O15270,P05023,O00429,P40939,P00846,Q13217 11 +Generalized onset motor seizure 0.3642850805566821 1.3486748722264534 0.1774414199768426 1.0 0.7701220625969445 52 Q9Y5U9,P03886,P21912,Q86SQ9,P16278,P07602,Q9NZJ7,Q96N66,O60762,Q01105,Q9Y619,P04062,O60566,P00846,Q13510,O00429,Q9BTW9 17 +Parkinsonism 0.4051110241839802 1.348290611952334 0.1775649304455957 1.0 0.7701220625969445 29 O43464,P07602,Q99720,Q9NZJ7,Q96RR1,O96008,Q96RL7,P04062,Q06787,O75569,P05067,P35637 12 +Headache 0.3552680719137381 1.3456046882362946 0.1784300389019739 1.0 0.7701220625969445 61 P23786,P00846,Q96RR1,P12235,Q969G3,P04062,Q9BW27,P21912,Q8N1F7,P03886,O60313,Q8NFH4,P00387,P10644,O00429,Q9NZ08,Q9NQZ5,Q05655,P05067 19 +Skin nodule 0.4460917248973142 1.3442915793979584 0.1788541174648523 1.0 0.7701220625969445 19 P06280,P16615,Q13510,Q9NZ08,P35637 5 +Partial agenesis of the corpus callosum 0.5221066090288888 1.343131196765809 0.179229495506914 1.0 0.7706190690557202 11 Q86WC4,Q15392 2 +Abnormality of retinal pigmentation 0.3454338510568424 1.340811922150262 0.1799815243991331 1.0 0.7723243916830301 68 Q86SQ9,Q92620,Q9UG56,P00846,Q7KZN9,Q9P0J0,P53701,P21912,P51648,O75381,P03886,O76024,Q15067,Q15555,O75306,P51812,P40855,Q96CU9,Q96S66,Q9Y5Y5,Q16836 21 +Triangular mouth 0.6097202031382558 1.3395995742430071 0.1803755623197909 1.0 0.7723243916830301 6 Q10713 1 +Abnormal sternal ossification 0.7651515151515355 1.337346646328794 0.1811095113798366 1.0 0.7730759386529675 4 Q9Y619,Q08AM6,O95202 3 +Abnormality of metacarpal epiphyses 0.7651515151515329 1.3373466463287838 0.18110951137984 1.0 0.7730759386529675 4 P51812,O95202,P16435 3 +Retinal pigment epithelial mottling 0.8696679030635712 1.3367980929000154 0.1812885518875484 1.0 0.7730759386529675 3 P00846 1 +B cell lymphoma 0.6477278779025377 1.335065286868683 0.1818549795399044 1.0 0.7734581879480015 5 Q05655,Q9H0U3 2 +Variable expressivity 0.3312554368357254 1.3331314038704674 0.1824886853014458 1.0 0.7743852886532434 76 Q9H061,P03886,Q86SQ9,P07602,O95470,P17900,Q9NZJ7,Q6P4A7,Q53H12,P55201,Q13510,P00374,Q70HW3 13 +Skeletal dysplasia 0.3715435195571164 1.330383435690689 0.1833919693383705 1.0 0.7756873074274769 40 Q9HC07,Q96L58,P16278,P40855,Q96HY6,P07237,P10619,Q14739,Q9Y5Y5,P51648,O75381 11 +Abnormal thalamic mri signal intensity 0.7625510186436911 1.326454107258634 0.1846893267715663 1.0 0.7756873074274769 4 Q96RR1,Q9GZY8 2 +Hypoplastic female external genitalia 0.4763166352118337 1.3261967285781089 0.1847745426308067 1.0 0.7756873074274769 14 Q9Y619,Q08AM6,P16435 3 +Abnormality of the clitoris 0.4299847684115548 1.3260675163722877 0.1848173346451296 1.0 0.7756873074274769 22 Q08AM6,P40855,P53701,P16435,Q9Y619,O75381 6 +Temporal cortical atrophy 0.8668210509301972 1.3256302756798857 0.1849621927726925 1.0 0.7756873074274769 3 O43924 1 +Abnormal cochlea morphology 0.8668147910302777 1.325605720263654 0.1849703304887615 1.0 0.7756873074274769 3 Q9Y619 1 +Enlarged thorax 0.4761570140057772 1.325109240377803 0.1851349217836837 1.0 0.7756873074274769 14 O75844,Q14739 2 +Abnormal morphology of the musculature of the neck 0.4823376520862165 1.3243335222816193 0.1853923020104892 1.0 0.7758505812748075 13 Q99720,P35637,Q96L58,P04350 4 +Widened cerebral subarachnoid space 0.7615239886470806 1.3221517959965532 0.1861176089608864 1.0 0.7760302503786183 4 Q9BV10 1 +Abnormal pulmonary thoracic imaging finding 0.4470655532770107 1.3201622423857269 0.1867808552592951 1.0 0.7764925403011848 18 Q05655,P04062,Q13510,P21964,Q9NZ08 5 +Morning glory anomaly 0.8462804476629369 1.3199599454871125 0.1868483915042587 1.0 0.7764925403011848 2 O60313 1 +Temporal optic disc pallor 0.8462804476629369 1.3199599454871125 0.1868483915042587 1.0 0.7764925403011848 2 O60313 1 +Sea blue histiocytosis 0.8649983536384558 1.3184807475056848 0.1873427657777542 1.0 0.7772306841175691 3 P16278,O15118 2 +Bilateral microphthalmos 0.6441193462503187 1.3182180722933852 0.1874306573921682 1.0 0.7772306841175691 5 Q9UHX1 1 +Wide cranial sutures 0.5845739865464712 1.3156603385663472 0.1882880717455752 1.0 0.7773849104466433 8 Q08AM6,O75844 2 +Non midline cleft lip 0.604802114957169 1.3150840306758007 0.1884816629448478 1.0 0.7773849104466433 6 Q96L58 1 +Bruising susceptibility 0.4050177475606299 1.3095896461603815 0.1903346929511542 1.0 0.778104690920943 27 P38435,Q96L58,Q14108,Q13126,Q05655,P04062,Q8NCH0,Q9NWM8 8 +Tapered finger 0.3822673786848547 1.3077891300398483 0.1909448420934019 1.0 0.778104690920943 36 Q15907,Q08AM6,P51812,P23786,P42892,Q8NCH0 6 +Arrhinencephaly 0.5586292894024747 1.3066850265347674 0.1913197060849514 1.0 0.778104690920943 9 P21964 1 +Decreased muscle mass 0.4733137725769358 1.30572580907454 0.1916458178578093 1.0 0.778104690920943 14 P04066,O96028,O95202,P46976,Q8NCH0,Q9Y487 6 +Positional foot deformity 0.3243719282816263 1.3047032007892276 0.1919939311610767 1.0 0.778104690920943 88 Q15907,Q9UHX1,Q5H8A4,Q96A33,Q9HC21,P55201,P16435,Q9Y619,Q8NCH0,Q9BV10,P21964,Q15392,Q9Y487,Q9NWM8,P08236 15 +Proportionate short stature 0.3903426078703514 1.3036448214275858 0.1923547109854457 1.0 0.778104690920943 33 Q96L58,P16278,Q96HY6,P53701,Q9Y619,P10619,Q14739,Q15392,P21912,Q5JRA6,Q16836 11 +Poor wound healing 0.6408023510310366 1.3027238048318877 0.1926690719990551 1.0 0.778104690920943 5 O15269,P04062 2 +Abnormal pharynx morphology 0.3784366429242106 1.300153316010619 0.1935484273099248 1.0 0.778104690920943 37 P16278,Q13277,Q05655,Q9BV10,Q13510,Q03518,P15586,P08236,P54802 9 +Spastic paraplegia 0.3617538239092512 1.29815635307587 0.1942336130071476 1.0 0.778104690920943 49 Q9P0J0,O75306,Q96CU9,O60313,O00754,P56192,Q9Y619,O00400,P04062,O00429,Q7KZN9,P00846,O94905 13 +Ankle clonus 0.4968941547329177 1.2981108311171228 0.1942492529495956 1.0 0.778104690920943 12 Q9NZJ7,O60220 2 +Fever 0.3322835829093391 1.2979271755981958 0.1943123607136054 1.0 0.778104690920943 74 P07602,Q9NZJ7,P23786,P10253,P00846,Q15645,P06280,P51572,Q13510,Q9BW27,Q8N1F7,P03886,P35610,P28070,Q8NFH4,P10644,Q9NZ08,Q9HC07,P49770,Q9NR50,Q05655,Q14739 22 +Mandibular aplasia 0.6392636787729573 1.2955339455442758 0.1951360990743511 1.0 0.7807160199553416 5 Q9Y619 1 +Paroxysmal involuntary eye movements 0.4352240460936071 1.2943370922869455 0.1955490095463679 1.0 0.7809032737265372 20 O75306,P03886,Q96CU9,Q86Y39,O96000,O43676 6 +Aplasia hypoplasia of the hallux 0.4391567292114223 1.29156612210719 0.19650744260108 1.0 0.7821096376083726 19 Q9UHX1,Q7LGA3,Q5H8A4 3 +Progressive spastic paraplegia 0.4029256831683939 1.291272731888709 0.1966091225483384 1.0 0.7821096376083726 27 Q96CU9,O00400,Q7KZN9,P00846 4 +Short ribs 0.55572266830444 1.2906291109903998 0.1968323165606591 1.0 0.7821096376083726 9 Q9Y619,Q08AM6,Q14739,Q9BV10 4 +Angiokeratoma 0.7539525691699765 1.2904284085594806 0.1969019538211869 1.0 0.7821096376083726 4 P04066,P06280,P16278 3 +Abnormality of fundus pigmentation 0.8574970947107514 1.289064519741658 0.1973756570618623 1.0 0.7821096376083726 3 Q9Y619 1 +Hypopigmentation of the fundus 0.8574970947107514 1.289064519741658 0.1973756570618623 1.0 0.7821096376083726 3 Q9Y619 1 +Finger agnosia 0.8387096774193352 1.2878711770733846 0.197790810258903 1.0 0.782391648580652 2 P05067 1 +Deposits immunoreactive to beta amyloid protein 0.8387096774193352 1.2878711770733846 0.197790810258903 1.0 0.782391648580652 2 P05067 1 +Juvenile onset 0.3638855679576023 1.2870783456757124 0.1980669821925449 1.0 0.7828033900902579 41 P06280,Q9H0U3,P16278,P49770,Q9NR50,P54802,O75027,Q13510,O14773,O15118 10 +Aplasia hypoplasia involving the vertebral column 0.4567501600525776 1.2834472787295648 0.1993354190061484 1.0 0.7839830183555493 16 Q96HY6,P16278,P04066,Q6NUQ1,P10644,Q14739,O43909,Q9H9E3,P08236 9 +Polyhydramnios 0.3606489153568744 1.279873793903871 0.2005895255294882 1.0 0.7839830183555493 48 Q08AM6,Q14739,Q9BV10,P21964,O75844,Q70HW3 6 +Brushfield spots 0.7513175230566687 1.279386128123045 0.2007611163223517 1.0 0.7839830183555493 4 P40855,O75381,Q9Y5Y5 3 +Thin ribs 0.4937751046129182 1.2782008091604906 0.2011786309169867 1.0 0.7839830183555493 12 O75844 1 +Progressive sensorineural hearing impairment 0.5112847521563856 1.2770957161630412 0.2015684570819882 1.0 0.7839830183555493 11 P03886,O76024,O60220 3 +Left ventricular systolic dysfunction 0.634992169891512 1.2755667783491431 0.2021087041219036 1.0 0.7839830183555493 5 O75844 1 +Hyperextensible skin 0.4688060777408508 1.274947808867317 0.2023277155790075 1.0 0.7839830183555493 14 Q9UHX1,P04062,Q9NWM8,Q8NCH0 4 +Abnormal brain n acetyl aspartate level by mrs 0.8535582884421463 1.2736246953384516 0.2027964559048323 1.0 0.7839830183555493 3 Q9NZJ7 1 +Reduced brain n acetyl aspartate level by mrs 0.8535582884421463 1.2736246953384516 0.2027964559048323 1.0 0.7839830183555493 3 Q9NZJ7 1 +Abnormal brain choline level by mrs 0.8535582884421463 1.2736246953384516 0.2027964559048323 1.0 0.7839830183555493 3 Q9NZJ7 1 +Overlapping toe 0.4234267062848768 1.2734840112948034 0.2028463426257378 1.0 0.7839830183555493 22 Q15907,Q9UHX1 2 +Confusion 0.4545969997704343 1.2680599629393818 0.2047765378401029 1.0 0.7885107675843414 16 P36551,Q9UJS0,O00754,O96008,Q9Y619,P49327,P40939,Q9NZ08,Q16836,P05067 10 +Angina pectoris 0.7474091290314151 1.263007143931673 0.2065866123439144 1.0 0.7912378020302424 4 O75844 1 +Abnormality of the amniotic fluid 0.3181559660371788 1.2574596723250426 0.2085872331544667 1.0 0.7912378020302424 84 Q08AM6,Q9UHX1,P23786,P16435,Q14739,Q9BV10,P04062,P21964,Q9BT22,O75844,Q70HW3,Q7LGA3 12 +Abnormality of the spleen 0.3359557093169742 1.257164756942439 0.2086939821372915 1.0 0.7912378020302424 110 P54802,P07602,Q9NZJ7,Q14108,P10253,Q10713,Q15392,Q9BT22,P61916,P08236,Q96A33,P16278,P04062,Q13510,P15586,P28070,Q86WC4,P10619,P21964,Q9NZ08,Q96HY6,Q05655,Q14739,O15118 24 +Protruding tongue 0.5248227005138735 1.2566016646133464 0.2088979116813192 1.0 0.7912378020302424 10 Q6NUK1,Q10713 2 +Incoordination 0.3428167553743625 1.2552097521360783 0.2094026262622319 1.0 0.792489639656317 65 Q6DKK2,P07602,Q9NZJ7,Q10713,P00846,O14773,O00165,Q96RR1,P12235,P04062,P40939,Q13510,P21912,O75503,O00754,Q15067,Q9Y619,Q01105,Q9UBB4 19 +Papule 0.4456679903423282 1.2545417268540118 0.2096451690447278 1.0 0.7927480249247439 17 Q9NZ08,P38435,O75844 3 +Abnormality of coagulation 0.3526380603951919 1.2538132922274974 0.2099098766741716 1.0 0.7930897250754209 56 Q6NUQ1,O43826,Q9BV10,P28288,Q9P2J5,P15291,O75381,P51571,Q9Y619,P16930,Q86WC4,P10644,Q9Y487,Q9H9E3,P38435,P40855,Q9UJS0,O60762,Q9Y5Y5,Q5XKP0,Q16836 21 +Crumpled long bones 0.8304805793285052 1.253042390872806 0.2101902798287169 1.0 0.7932033938263563 2 P07237 1 +Abnormal circulating gonadotropin concentration 0.4716332415271835 1.2527719866755993 0.2102886992645825 1.0 0.7932033938263563 13 P16870,Q969G3,P16435,Q15031,P57740,Q06787,Q8IY37 7 +Bronchitis 0.5915126487934811 1.248712425489936 0.2117702745255585 1.0 0.7974693533251372 6 Q03518,Q05655 2 +Nyctalopia 0.3958627845933448 1.2466966709201974 0.2125087399648768 1.0 0.797935777575023 28 O95140,P38435,P40855,Q86SQ9,Q92620,Q15555,Q96S66,Q10713,P40939,Q9Y5Y5,P50542,Q9H9E3,O75381 13 +Anomalous trichromacy 0.8465591043793149 1.246202498885579 0.2126900618955538 1.0 0.797935777575023 3 O60313,Q9H6K4 2 +Tritanomaly 0.8465591043793149 1.246202498885579 0.2126900618955538 1.0 0.797935777575023 3 O60313,Q9H6K4 2 +Enlarged kidney 0.590809588756695 1.2451966629792677 0.2130594689519882 1.0 0.7979968285845498 6 P23786,O43826 2 +Low frustration tolerance 0.5471939938189155 1.2434350067086155 0.2137075770356498 1.0 0.7979968285845498 9 Q9UHX1 1 +Polydactyly 0.3631207257629649 1.243075550923063 0.213839994294255 1.0 0.7979968285845498 40 Q9UHX1,Q5H8A4,Q9BXW9,O43924,Q15125,O96028,O95202,P61978,Q15067,O43909,Q10713,Q14739,P21964,Q9UM00 14 +Abnormal lumbar spine morphology 0.5051642480810683 1.239633552005326 0.2151109647366396 1.0 0.7998847062223409 11 P51812,O00754,P04062,O43909,P08236 5 +Hypocalcemia 0.4634601531402778 1.2383757903337602 0.2155767530948757 1.0 0.7998847062223409 14 Q86WC4,P21964 2 +Abnormal connection of the cardiac segments 0.3567898737443055 1.2375221456624343 0.2158932979238599 1.0 0.7999332516257615 48 Q08AM6,Q9UHX1,Q9Y4P3,P21964,O75844 5 +Abnormal venous morphology 0.4040138387830494 1.237362448198627 0.2159525533942443 1.0 0.7999332516257615 25 Q9Y487,P04062,Q05655,P21964 4 +Retinal dysplasia 0.5458043886241164 1.2357346104528064 0.2165572279868965 1.0 0.7999332516257615 9 O43505,O43924,Q10713 3 +Abnormal circulating ceruloplasmin concentration 0.8436345104015549 1.2347505704707775 0.2169233486897666 1.0 0.7999332516257615 3 O00400 1 +Biliary tract neoplasm 0.7406057339186469 1.2344968187206145 0.217017831436413 1.0 0.7999332516257615 4 Q9NZJ7 1 +Neoplasm of the gallbladder 0.7406057339186469 1.2344968187206145 0.217017831436413 1.0 0.7999332516257615 4 Q9NZJ7 1 +Decreased circulating level of specific antibody 0.5735317933196982 1.2335727995623618 0.2173621338967866 1.0 0.7999332516257615 7 Q05655,Q9BV10 2 +Vascular skin abnormality 0.3334996987396382 1.231243962291935 0.2182316335651184 1.0 0.7999332516257615 109 Q8IZA0,Q14108,Q13126,P00846,Q06136,P06280,P16278,Q6NUK1,P04062,Q8NCH0,P51648,O75844,Q9NWM8,P03886,P10619,P21964,Q9Y487,P51812,P38435,Q05655,Q14739 21 +Truncus arteriosus 0.5684275149754108 1.2311574612073957 0.2182639778714419 1.0 0.7999332516257615 8 Q9UHX1 1 +No social interaction 0.8252139565503627 1.2307846795830135 0.2184034070167153 1.0 0.7999332516257615 2 Q15067 1 +Broad metacarpals 0.8252139565503578 1.230784679582994 0.2184034070167226 1.0 0.7999332516257615 2 P16278 1 +Abnormality of the ischium 0.8252139565503407 1.2307846795829211 0.2184034070167499 1.0 0.7999332516257615 2 Q8IZA0 1 +Impaired social interactions 0.3553467356653209 1.2274273342871775 0.2196620179390458 1.0 0.8026044334174455 49 Q9P0J0,Q15907,Q9UHX1,P03886,O75306,Q9NPL8,Q9GZY8,Q86Y39,Q96CU9,Q96RR1,O96000,Q15067,O43676,O43909,Q10471,Q5XKP0 16 +Abnormal femoral neck head morphology 0.3573660455051171 1.225982965345777 0.2202050854899557 1.0 0.8032982629461177 44 O75718,Q96L58,Q6NUQ1,O43909,Q96A33,P16278,O75844,P04066,O00754,O75431,Q9Y619,Q9Y487,Q9H9E3,Q7LGA3,P51812,Q96HY6,Q14739,P50542,O95831,P55011 20 +Aplasia hypoplasia of the femur 0.4551011299121871 1.2242767804227692 0.2208478331613399 1.0 0.8049974303292751 15 Q9UHX1,Q96HY6,Q96L58,O00116,O75431,Q9BV10,P50542 7 +Abnormality of the cerebrospinal fluid 0.3478530952725914 1.2231382011780525 0.2212775021636852 1.0 0.8051852170990754 134 O43505,Q9HC21,Q96L58,Q86Y39,P07602,Q9NZJ7,O96000,P23786,O60566,P00846,Q15392,Q10713,Q7KZN9,P08236,Q9P0J0,Q08AM6,P53701,Q969G3,P16435,Q6NUK1,P07237,P04062,Q96I36,P13073,P15291,P03886,O00754,O43676,Q86WC4,P21964,O75306,Q9NPL8,P40855,Q96CU9,O95202 35 +Pulmonary fibrosis 0.4340186774234758 1.222308626028843 0.2215909384449255 1.0 0.8051852170990754 18 P09601,P04062,Q05655,Q8IZA0 4 +Joint subluxation 0.5859761897488845 1.221016315184618 0.2220798425335668 1.0 0.8051852170990754 6 Q9UHX1,P16278 2 +Cardiac valve calcification 0.7373089790391781 1.2206831569929566 0.2222060073397398 1.0 0.8051852170990754 4 O75844 1 +Mitral valve calcification 0.7373089790391781 1.2206831569929566 0.2222060073397398 1.0 0.8051852170990754 4 O75844 1 +Small basal ganglia 0.5659547776420318 1.2181859552503738 0.2231533155847798 1.0 0.8056543115834629 8 P00846 1 +Migraine 0.4209623498720192 1.2172436012701502 0.2235115455008054 1.0 0.8060687294185875 21 P03886,O60313,P12235,Q9NQZ5,O00429,Q9NZ08,P05067 7 +Abnormal clavicle morphology 0.4293176369573918 1.2164782038539197 0.2238028090801851 1.0 0.8060687294185875 19 Q9Y619,O75844,Q14739 3 +Severe failure to thrive 0.8385753374624654 1.214950698880176 0.224384895443539 1.0 0.8060687294185875 3 O75844 1 +Secondary microcephaly 0.3293842268884045 1.2147965389570978 0.2244437012275726 1.0 0.8060687294185875 72 Q9UHX1,Q9HC21,Q86Y39,P55795,O43909,Q9BV10,Q9BSJ2,Q9BT22,P50897,Q9BTW9,Q9NXE4,Q9GZY8,O95721,P00374,Q9Y487,Q9HC07,P49770,Q96CU9,Q9NR50,O60762,Q5XKP0 21 +Infectious encephalitis 0.5644824533365368 1.2104590607073262 0.2261027908911193 1.0 0.8092380769187267 8 Q9NZ08,Q14739 2 +Retinal degeneration 0.3495916979536252 1.2087796587538089 0.2267475083889818 1.0 0.8109075594822943 55 Q86SQ9,P50897,O60313,O00754,Q92620,Q9H2C2,Q9UG56,P04439,Q96S66,P04062,Q10713,Q13510,P51648,O14773,Q7LGA3,O75503 16 +Glomerulopathy 0.5159127975971576 1.2042004066995164 0.2285121288372302 1.0 0.8126708831866665 10 Q14108,Q9NZ08 2 +Abnormality of the pharynx 0.3544164055652833 1.2017252197900834 0.2294700066134352 1.0 0.8126708831866665 46 P16278,Q13277,Q05655,Q9BV10,Q13510,P21964,Q03518,P15586,P08236,P54802 10 +Nocturia 0.8179723502303944 1.2002289183895527 0.2300504471363789 1.0 0.8126708831866665 2 P12235 1 +Multiple mitochondrial dna deletions 0.8179723502303944 1.2002289183895527 0.2300504471363789 1.0 0.8126708831866665 2 P12235 1 +Diaphyseal thickening 0.8346028198909388 1.1994141416510449 0.2303669514728419 1.0 0.8126708831866665 3 Q14739 1 +Absent toe 0.4142026370084327 1.199254849651692 0.2304288654541506 1.0 0.8126708831866665 22 Q9UHX1,Q7LGA3,Q5H8A4 3 +Decreased pulmonary function 0.8169848584595054 1.196067003250234 0.2316704129269116 1.0 0.8126708831866665 2 P08236 1 +Hemifacial spasm 0.8169848584595041 1.1960670032502292 0.2316704129269133 1.0 0.8126708831866665 2 Q10713 1 +Abnormal cellular phenotype 0.3680100380404403 1.1959073824217437 0.2317327039389241 1.0 0.8126708831866665 181 Q86Y39,O60220,P09601,Q9Y2R0,Q9NZJ7,P23786,P07602,O96000,Q9BUB7,Q14108,P46976,O43909,O60566,P00846,Q9BV10,Q00325,Q15645,Q7KZN9,O14773,O75880,P51530,P35637,Q9P0J0,Q9H0U3,Q9GZY8,Q96RR1,P12235,Q969G3,O60783,P04062,Q13510,P21912,P13073,O75844,Q9UBX3,Q70HW3,P15586,O75503,P03886,Q4J6C6,Q9Y584,Q3ZCQ8,P28070,O00754,O43676,O00429,P21964,Q92643,O75306,Q9NPL8,Q96CU9,Q9UJW0,Q05655,Q14739,Q16836 55 +Abnormal nipple morphology 0.3527232673180536 1.192772552337474 0.2329584624145271 1.0 0.8141727077534975 48 Q08AM6,Q96A33,Q5H8A4,Q9NXE4,P23786,O96028,O95202,O60762,Q15067,Q15555,Q6NUK1,Q9BV10,Q9UM00,Q7LGA3 14 +Preaxial polydactyly 0.4626666413128918 1.1926105805104603 0.2330219201736758 1.0 0.8141727077534975 13 O43924,Q9UHX1,Q9BXW9,Q5H8A4,O95202,O43909 6 +Head titubation 0.5655147617489094 1.1921161022657505 0.2332157240378591 1.0 0.8141727077534975 7 Q99720 1 +Retinal dystrophy 0.3521189105504506 1.1916769127269442 0.2333879540872481 1.0 0.8141727077534975 49 O43505,P03886,P38435,P40855,Q86SQ9,P53701,Q9H2C2,Q15067,Q10713,P00846,Q9Y5Y5,O75381 12 +Retinal thinning 0.8153390388413158 1.1891331959229257 0.2343872573133303 1.0 0.8141727077534975 2 P51648 1 +Disproportionate tall stature 0.3926067548963636 1.1848495392246114 0.236076941636175 1.0 0.8141727077534975 26 Q5H8A4,P36543,O00754,O96028,O95202,P16435,Q15031,Q8NCH0,Q9NWM8,P55011,Q7LGA3 11 +Shuffling gait 0.4791805324105941 1.1847505804027596 0.2361160774060506 1.0 0.8141727077534975 12 O75844,P04062 2 +Aortic valve calcification 0.8304370372956319 1.1831329431722488 0.2367564636544255 1.0 0.8141727077534975 3 O75844 1 +Microretrognathia 0.4426544609604965 1.182483591681821 0.2370138723593957 1.0 0.8141727077534975 16 Q9UHX1 1 +Abnormality of salivation 0.3537848481772114 1.1804336849123953 0.2378277711744363 1.0 0.8141727077534975 41 Q08AM6,P51812,P55795,Q15165,O43909,Q14739,Q92804,P15586,P35637 9 +Abnormal conjunctiva morphology 0.4021289009631941 1.1783119139176013 0.2386722798544829 1.0 0.8141727077534975 24 P28070,P10619,Q14739,Q13510,Q9NZ08 5 +Generalized onset seizure 0.3211173905225774 1.177788511901285 0.2388809296740233 1.0 0.8141727077534975 96 Q86SQ9,P07602,Q9NZJ7,Q96N66,Q14108,O43909,O60566,P00846,Q9BTW9,Q9NZ01,P16278,P04062,Q13510,P21912,Q9NVI7,O75503,Q9Y5U9,P03886,O14653,Q9Y619,Q86WC4,O00429,P00374,P51812,P04080,O60762,Q01105,P05023,Q9Y320,Q9UBB4 30 +Flat face 0.3898621851833862 1.1764569745941054 0.2394123159056029 1.0 0.8141727077534975 27 O75381,Q03164,Q96L58,P40855,Q15125,O00754,P55201,Q9BUB7,Q9NX62,Q15555,Q9Y5Y5,Q9Y487,Q9UM00,P08236 14 +Chorioretinal coloboma 0.613359666382238 1.174333815373377 0.2402613437722047 1.0 0.8141727077534975 5 Q10713,O14936 2 +Gingival overgrowth 0.3835942672591073 1.1740458297192184 0.2403766692584714 1.0 0.8141727077534975 30 Q9Y5U9,P16278,O00754,Q9Y4P3,Q96S52,P10644,Q86WC4,O43909,Q14739,P08236 10 +Subcutaneous hemorrhage 0.3765963413446329 1.17388655431576 0.2404404687447876 1.0 0.8141727077534975 33 P38435,Q96L58,Q14108,Q13126,Q05655,P04062,P21964,Q8NCH0,Q9NWM8 9 +Unilateral renal agenesis 0.4237309899530329 1.173714148910933 0.2405095410407292 1.0 0.8141727077534975 19 Q9UHX1,Q7LGA3,P16435 3 +Barrel shaped chest 0.7260761255627605 1.173635854465244 0.2405409134495562 1.0 0.8141727077534975 4 Q14739 1 +Focal white matter lesions 0.5764975653197344 1.173554140880034 0.2405736589744362 1.0 0.8141727077534975 6 O00584,Q96RR1,P12235 3 +Short upper lip 0.7259552042160815 1.173129618602725 0.2407438306102434 1.0 0.8141727077534975 4 Q08AM6,O96028,O95202 3 +Abnormal circulating fatty acid concentration 0.4344951268133702 1.1725191777423811 0.2409886771232534 1.0 0.8141727077534975 17 P40855,P23786,O75431,P40939,P50542,O75880,Q9Y5Y5,Q16836,O75381 9 +Hypointensity of cerebral white matter on mri 0.5761546219160506 1.171836082092075 0.2412628731703043 1.0 0.8141727077534975 6 Q9NZJ7 1 +Abnormal labia minora morphology 0.560285282393403 1.165045660641203 0.2440005106729148 1.0 0.8174317160685798 7 Q9Y619 1 +Bifid scrotum 0.6112681750887841 1.1645418188274796 0.2442045063453799 1.0 0.8174317160685798 5 P16435 1 +Ectopic calcification 0.3485128511752933 1.1640810498613698 0.2443911674786993 1.0 0.8174317160685798 51 O00584,P23786,P08236,P04062,P53680,P53634,O75844,O75381,P03886,O60313,Q15125,O75431,P10644,O00429,P38435,P40855,O00116,O43175,Q14739,Q9Y5Y5,P05067 21 +Steroid resistant nephrotic syndrome 0.6106574950037988 1.161682739595788 0.2453643593843351 1.0 0.8178000501751483 5 Q8N1F7,Q9BW27 2 +Skeletal muscle hypertrophy 0.355104714049878 1.1595497834230424 0.24623215639699 1.0 0.8178000501751483 40 Q96A33,P16278,P04066,O00754,Q9Y4P3,P10253,Q10713,O94905,P21912,Q7LGA3 10 +Wide anterior fontanel 0.4045490670504522 1.158425859303579 0.2466902913505726 1.0 0.8178000501751483 23 O75718,P40855,Q15125,Q16134,P16435,Q6NUK1,P42345,Q9Y5Y5,Q9Y487,Q9H9E3,O75381 11 +Aplasia hypoplasia of the clavicles 0.4573907956474096 1.1571337681833933 0.2472177122132828 1.0 0.8178000501751483 13 Q9Y619,O75844 2 +Abnormal csf metabolite level 0.342525994938539 1.1569631225549448 0.2472874273283556 1.0 0.8178000501751483 58 P03886,Q9HC21,Q96CU9,Q86Y39,O96000,O43676,P00846,Q7KZN9,Q96I36,P13073 10 +Meningitis 0.6096344260419415 1.156892986221187 0.2473160846326227 1.0 0.8178000501751483 5 Q9NZ08,P49327,O15460 3 +Diffuse cerebral atrophy 0.4454867520608011 1.1568214442678728 0.2473453186607164 1.0 0.8178000501751483 15 Q9H936,P16278,P07602,Q9NZJ7,O00429,Q10713,Q06787,Q9BTW9 8 +Premature loss of primary teeth 0.7220026350461124 1.15658572616927 0.2474416567386086 1.0 0.8178000501751483 4 P53634,Q08AM6,P04080 3 +Pericarditis 0.6094352501185156 1.1559605030369406 0.2476973129180737 1.0 0.8178000501751483 5 Q9NZ08,O15460 2 +Decreased ldl cholesterol concentration 0.7215755839219745 1.1547986942237514 0.2481728719631837 1.0 0.8178000501751483 4 Q15800,P37268 2 +Bilateral coxa valga 0.8071099407504707 1.1545187232191985 0.2482875669509185 1.0 0.8178000501751483 2 Q96A33 1 +Hydrops fetalis 0.3497506389422318 1.1508818595759436 0.2497808416924101 1.0 0.8178000501751483 46 Q08AM6,O96000,Q05655,P04062,P10619,Q13510,Q14739,Q9BT22,P08236 9 +Gastric ulcer 0.8218433385460764 1.149587814945985 0.2503136792159752 1.0 0.8178000501751483 3 P04062 1 +Cardiovascular calcification 0.552689054103927 1.148486606613893 0.2507677389432556 1.0 0.8178000501751483 8 O75844 1 +Abnormality of alkaline phosphatase level 0.4164542229559348 1.1484196660368242 0.2507953589850364 1.0 0.8178000501751483 20 Q92643,Q96A33,Q9UJS0,Q14739,Q8N511,Q9H9E3,P22626 7 +Decreased light and dark adapted electroretinogram amplitude 0.8214933202257835 1.148222852758783 0.2508765775003714 1.0 0.8178000501751483 3 P50897 1 +Dysesthesia 0.6074283211943624 1.146564875442648 0.2515615002091929 1.0 0.8185399878071918 5 O15270,Q8NCH0 2 +Abnormal aortic valve physiology 0.3569548979801429 1.1458446876608186 0.2518594210867246 1.0 0.8185399878071918 39 Q6ZXV5,Q9NZ08,Q9UHX1,Q5T2R2,P16278,Q9Y4P3,Q96PU5,O60566,P04062,Q15645,O75844 11 +Decreased circulating acth level 0.8048057932850567 1.1448442042308762 0.2522737003529607 1.0 0.8185399878071918 2 Q969G3 1 +Congenital craniofacial dysostosis 0.8048057932850485 1.144844204230842 0.2522737003529749 1.0 0.8185399878071918 2 Q6NUK1 1 +Abnormal lung development 0.3500981904229003 1.1413476516355487 0.2537252796929454 1.0 0.8209077505854971 41 Q9UHX1,Q5H8A4,Q96L58,O96000,O95202,Q6NUK1,Q14739,O60566,P21964,O75844 10 +Cranial asymmetry 0.7180070382584901 1.1398695309083484 0.2543406606242184 1.0 0.8211466750742156 4 O95202,P40855 2 +Thin skin 0.4062837866164323 1.1353156173417247 0.256243100974534 1.0 0.8218699472535232 22 Q6ZXV5,Q96L58,O75431,Q9Y619,Q13126,P10644,Q96PU5,Q9H4L7,O75844 9 +Abnormal basal ganglia mri signal intensity 0.3851428853235049 1.1348165940235229 0.2564521719819648 1.0 0.8218699472535232 27 Q9P0J0,P03886,P16278,Q9GZY8,Q96CU9,Q7KZN9,P00846 7 +Increased intracranial pressure 0.4422365464624193 1.133974710515361 0.2568051562753211 1.0 0.8220346019737919 15 P07602,Q9NZJ7,Q969G3,P21912,Q9NZ08 5 +Myoclonic spasms 0.8172538689496096 1.1316993315283248 0.2577608626778844 1.0 0.8226383885667415 3 Q10713,P00846 2 +Color vision defect 0.4535826858861495 1.1314957372135075 0.2578464966023883 1.0 0.8226383885667415 13 Q9H061,O60313,O60220,Q9H6K4 4 +Ureteral duplication 0.7159873558459906 1.1314232952370329 0.2578769712236037 1.0 0.8226383885667415 4 O75844 1 +Abnormal renal tubule morphology 0.3863361241267718 1.130136681064645 0.2584186354765956 1.0 0.8237886284394068 26 P03886,P06280,P23786,Q9Y4P3,O43826,P00846 6 +Abnormal dermatoglyphics 0.3314299728219949 1.129466535710944 0.2587010786714057 1.0 0.8241114894091208 66 Q15907,Q9UHX1,O43909,Q08AM6,Q9NXE4,Q6NUK1,Q8NCH0,Q96I36,O75381,O96028,O75431,Q9Y4P3,P61978,Q9Y487,P51812,P40855,O95202,Q96S52,Q9Y5Y5,Q15042,Q9H4L7 21 +Abnormality of the phalanges of the toes 0.4216263774517413 1.1289153716687927 0.2589335356170572 1.0 0.8242747750328855 18 O75844,Q7LGA3 2 +Abnormality of the shoulder girdle musculature 0.3763229856204199 1.1273025029303645 0.2596146045248522 1.0 0.8245175676472926 31 P07602,O60313,Q9NZJ7,P12235,P46976,O14979,O00429,P50402,Q9Y487 9 +Low set posteriorly rotated ears 0.3285842946472034 1.127018131128612 0.2597348152206133 1.0 0.8245175676472926 68 Q5H8A4,Q96L58,O60566,Q10713,Q15392,Q15645,P16435,Q6NUK1,P04062,Q8NCH0,O75381,O43924,Q4J6C6,Q9Y4P3,Q15555,Q10471,P37268,P40855,O95202,Q9Y5Y5 20 +Hip pain 0.6028179010641216 1.1249832710642116 0.2605961232819294 1.0 0.8260687150517558 5 O75844 1 +Aplasia hypoplasia involving the metacarpal bones 0.395669189976939 1.1241292325022854 0.2609582056133879 1.0 0.8260687150517558 24 Q08AM6,P51812,Q96L58,Q9NX62,P16435,Q96S52,P10644,O43909,Q14739,Q9H9E3 10 +Abnormality of the anterior fontanelle 0.3713070264966934 1.1237208139293706 0.2611314836552565 1.0 0.8260687150517558 33 P51812,O75718,P40855,Q15125,Q16134,P16435,Q9Y619,Q6NUK1,P42345,Q9Y5Y5,P50542,Q9Y487,Q9H9E3,O75381 14 +Depletion of mitochondrial dna in muscle tissue 0.713771350181901 1.1221589684865838 0.261794855079891 1.0 0.8260687150517558 4 P12235,Q9UBX3 2 +Weak cry 0.547657505859622 1.1220109360776271 0.2618577900867513 1.0 0.8260687150517558 8 Q13510 1 +Focal t2 hyperintense basal ganglia lesion 0.4087680138189444 1.1205387825664752 0.2624842354724248 1.0 0.826104754648347 21 Q96CU9,P03886,Q7KZN9,P00846 4 +Ulnar deviation of the wrist 0.7131070210243506 1.119382277634772 0.2629770883038178 1.0 0.826189239511124 4 Q9BV10,P16435 2 +Oligohydramnios 0.3776109061870933 1.1193620473137984 0.2629857152807446 1.0 0.826189239511124 30 Q9UHX1,Q96L58,P23786,Q9BUB7,P16435,Q6NUK1,Q96I36,Q7LGA3 8 +Dermal atrophy 0.3950167772864082 1.1186504770802048 0.2632892801333077 1.0 0.8265720740693009 24 Q96L58,Q15392,Q8NCH0,O75844,Q9NWM8 5 +Unusual infection by anatomical site 0.4851578718995429 1.116712730774205 0.2641171727709472 1.0 0.8267011008114475 11 Q9BUB7,P49327,Q14739,O15460,Q9NZ08,Q9H9P8 6 +Emphysema 0.5501471545844828 1.112519452451413 0.2659148711223889 1.0 0.8302311247328394 7 Q05655,P06280 2 +Respiratory distress 0.3424433814480384 1.1097266341039858 0.2671168421847858 1.0 0.8315300112068283 53 Q9UHX1,P03886,Q96L58,P07602,P51571,Q9NZJ7,P23786,Q9Y619,P10253,P04062,P00846,Q13510 12 +Increased skull ossification 0.8115847651113492 1.1096315799712178 0.2671578171524336 1.0 0.8315300112068283 3 Q86WC4 1 +Hemianopia 0.599494498862872 1.1094296861777055 0.2672448618123506 1.0 0.8315300112068283 5 P03886 1 +Abnormal circulating acetylcarnitine concentration 0.5634421470162616 1.1081264098941277 0.2678072266827676 1.0 0.8327102352562609 6 P23786 1 +Morning myoclonic jerks 0.795918367346924 1.1076084664835444 0.2680309453941345 1.0 0.8328365919384686 2 Q14108 1 +Esodeviation 0.374117377210694 1.106873301127234 0.2683487106476037 1.0 0.8332548018675421 31 O43924,Q9UHX1,P04062 3 +Long hallux 0.7955892034233056 1.1062319710167778 0.2686261281499851 1.0 0.8334090036664866 2 P10644 1 +Brisk reflexes 0.3980413585287957 1.1048257078016788 0.2692351188042718 1.0 0.8342987434881695 23 Q9Y5U9,Q99720,Q10713,Q9BSJ2,Q5JRX3,P35637 6 +Molar tooth sign on mri 0.7090091226917467 1.102261291673347 0.2703480924590589 1.0 0.835574586417472 4 O43924 1 +Abnormal form of the vertebral bodies 0.3106937531852141 1.1008509937173585 0.270961513758492 1.0 0.8358288660214279 78 Q9UHX1,Q5H8A4,Q96L58,O43909,Q9BV10,Q10713,Q5JRA6,P08236,P16278,P16435,Q6NUK1,P07237,P15586,P04066,O00754,Q9Y4P3,Q9Y619,P10644,P51812,Q96HY6,O95202,Q14739,P54802 23 +Abnormal optical coherence tomography 0.7942725477287698 1.100727956026396 0.2710150752652465 1.0 0.8358288660214279 2 P04439 1 +Photoreceptor layer loss on macular oct 0.7942725477287698 1.100727956026396 0.2710150752652465 1.0 0.8358288660214279 2 P04439 1 +Atelectasis 0.4980980873052862 1.0990724952252615 0.2717364459253653 1.0 0.8369309025726808 10 Q13510,P21964 2 +Central nervous system cyst 0.3421486769769686 1.0990634981868677 0.271740369993372 1.0 0.8369309025726808 52 O43505,Q9UHX1,Q15125,P23786,Q969G3,O96028,O95202,O43175,Q15031,P15291,O60566,P00846,Q15645,Q9BSJ2,Q9Y487 15 +Macular atrophy 0.561005637353651 1.095913400577757 0.2731166741002711 1.0 0.8385917167594854 6 P04062,Q92620 2 +Abnormal vertebral morphology 0.3174648753536861 1.0958454643465434 0.2731464084302868 1.0 0.8385917167594854 99 Q9UHX1,Q5H8A4,O75718,Q96L58,Q14108,O43909,Q9BV10,Q10713,Q5JRA6,P08236,P16278,P16435,Q6NUK1,P07237,P04062,Q8NCH0,P15586,P04066,O00754,Q9Y4P3,Q9Y619,P10644,P10619,P51812,Q96HY6,O95202,Q14739,P54802 28 +Single transverse palmar crease 0.3456758731343261 1.0957199570611922 0.2732013462821625 1.0 0.8385917167594854 42 Q15907,Q9UHX1,Q08AM6,P51812,P40855,O95202,O43909,Q9Y5Y5,Q96I36,Q9H4L7,O75381 11 +Vacuolated lymphocytes 0.8073756997036491 1.0932698849688536 0.2742753211339694 1.0 0.8409395941032652 3 P04066,P16278 2 +Abnormality of circulating glucocorticoid level 0.5201478304377856 1.0931317065907686 0.2743359766210695 1.0 0.8409395941032652 9 P04637,Q969G3,P16435,P10644,Q9NRG9,Q13423 6 +Flat occiput 0.447571990230647 1.0909845869674086 0.2752796647118318 1.0 0.8432267363604803 13 P40855,O00754,Q9BUB7,O60762,Q9Y5Y5,O75381 6 +Phenotypic variability 0.3162850682558011 1.088629614187046 0.2763172519988597 1.0 0.8432267363604803 98 Q86SQ9,P07602,Q9NZJ7,Q6P4A7,P46976,P57740,P00846,O95470,P17900,Q53H12,P55201,Q969G3,P04350,Q13510,P21912,Q70HW3,Q9H061,P03886,Q15125,O60313,P56192,Q92733,O14979,O00429,P00374,Q6PI48,Q06787,O60762,Q14671,Q9UBB4 30 +Emotional lability 0.3432237872250228 1.0878100509373994 0.2766789714905098 1.0 0.8434961258946649 48 Q9P0J0,O75306,P49770,Q96CU9,Q9UHD9,P07602,Q9NR50,Q9NZJ7,Q15165,Q969G3,Q7KZN9,Q92804,P35637 13 +Hypopigmented skin patches 0.3958033521325377 1.086369304148581 0.2773156364437057 1.0 0.8434961258946649 23 Q9BXW9,Q8IZA0,P07602,Q15125,Q9NZJ7,P53701,P49327,P42345,P21964,P21912,P53634 11 +Abnormality of the autonomic nervous system 0.341536406648887 1.0854704064706389 0.2777133638642572 1.0 0.8434961258946649 51 O43464,O43681,P06280,Q9BXW9,O76024,P07602,P0DP25,Q9NZJ7,Q96RR1,Q06787,P42892,Q15067,Q96RL7,O15269,P04062,Q10713,P21964,O15270 18 +Abnormality of exocrine pancreas physiology 0.4290371846942639 1.08452199233211 0.278133421336038 1.0 0.8434961258946649 16 Q9UHX1 1 +Enlarged ovaries 0.8050707935462534 1.0843189565616609 0.2782234030919404 1.0 0.8434961258946649 3 P21912,P16435 2 +Epispadias 0.5940793731432512 1.0840960830645436 0.2783221993774218 1.0 0.8434961258946649 5 Q9Y619 1 +Rod cone dystrophy 0.3567009998629108 1.083201108558621 0.2787191678035798 1.0 0.8441368138072469 37 P03886,P38435,P40855,Q86SQ9,Q92620,Q15067,P00846,Q9Y5Y5,O75381 9 +Vascular neoplasm 0.3713997289430034 1.0816796025670437 0.2793949197121392 1.0 0.8456204190089963 31 Q9UHX1,P10619,Q7LGA3,Q5H8A4 4 +Deep plantar creases 0.7019652253607432 1.0728636155626996 0.2833323129343603 1.0 0.8501838334686049 4 Q9Y487,P61978 2 +Type ii transferrin isoform profile 0.7873601053324565 1.0718858304160643 0.2837713153165717 1.0 0.8505044009769961 2 Q9H9E3 1 +Abnormality of earlobe 0.3940218159338963 1.071670056291513 0.2838682547909805 1.0 0.8505044009769961 23 Q7LGA3,Q15392,P21964 3 +Orthostatic hypotension 0.4391610118871055 1.0713767987559264 0.2840000406867569 1.0 0.8505044009769961 14 Q9NZJ7,P04062 2 +Pes valgus 0.5377279951626973 1.0697206649962288 0.2847450617381142 1.0 0.8516142576243796 8 Q9UHX1 1 +Aortic regurgitation 0.3792197001597296 1.0679049539024947 0.2855633876751229 1.0 0.8523804793531063 26 Q6ZXV5,Q9NZ08,Q9UHX1,Q5T2R2,Q96PU5,O60566,Q15645,O75844 8 +Hypolipidemia 0.7860434496379206 1.06640287130746 0.2862415642877778 1.0 0.8532849776835526 2 Q10471 1 +Hypotriglyceridemia 0.7860434496379206 1.06640287130746 0.2862415642877778 1.0 0.8532849776835526 2 Q10471 1 +Abnormal intraocular pressure 0.6997201049355394 1.0635031670633144 0.287553829711626 1.0 0.855670746503889 4 Q8NCH0 1 +Microcytic anemia 0.5889209006605307 1.0599778375430164 0.289154682018139 1.0 0.8563384480532749 5 Q9UBX3 1 +Ventricular tachycardia 0.4316358549788385 1.0593439770682669 0.2894431536897166 1.0 0.8563384480532749 15 P0DP25,Q9HD47 2 +Increased serum pyruvate 0.3615212984722283 1.0533320857865207 0.2921888183805816 1.0 0.8591900031113548 34 P03886,Q96CU9,Q86Y39,Q9BWD1,Q9NP80,O43676,Q5JRX3,Q70HW3 8 +Elevated circulating long chain fatty acid concentration 0.7965910483044333 1.0514472055145514 0.2930532448637584 1.0 0.8609835923547697 3 P23786 1 +Subcutaneous nodule 0.4243544862410143 1.050768761429736 0.2933648063538707 1.0 0.8609835923547697 16 Q9NZ08,Q13510,P35637 3 +Lower limb hyperreflexia 0.4111117311296545 1.0494284900237645 0.2939809514659646 1.0 0.8613187603843085 18 O00400,Q14739,P21912,Q15041,P13073 5 +Progressive spasticity 0.4302079710641771 1.0492809966392869 0.2940488096014138 1.0 0.8613187603843085 15 O43681,P51812,P07602,O60313,Q9NZJ7,P17900,Q9BTW9 7 +Atrophic scars 0.5376864260597433 1.0479190038672728 0.294675925804031 1.0 0.8615765806931 7 Q9NWM8,Q8NCH0 2 +Hypoparathyroidism 0.4891375222710903 1.046070927567102 0.2955282866550697 1.0 0.8632494683100471 10 P21964 1 +Saccadic smooth pursuit 0.6950987902721433 1.044252191988012 0.2963687254403924 1.0 0.864281694572209 4 Q10713 1 +Aplasia hypoplasia involving the pelvis 0.4404374610621773 1.0428449965389517 0.2970200875866453 1.0 0.864486539959523 13 Q5H8A4,Q96HY6,Q96L58,O95202,O75431,O96028,P50542 7 +Hyperconvex fingernails 0.5851669446689653 1.0424379588826191 0.2972086753950111 1.0 0.864486539959523 5 P51812,O95202 2 +Metaphyseal widening 0.4066000545744324 1.0421487482864364 0.2973427204613597 1.0 0.864486539959523 19 Q08AM6,Q96HY6,P16278,Q86WC4,Q14739 5 +Patchy changes of bone mineral density 0.7934975375564304 1.0394800429857036 0.2985815348917155 1.0 0.8656771206006464 3 Q14739 1 +Focal dystonia 0.389313234700823 1.0327938462974735 0.301700384148623 1.0 0.8687830497574704 23 Q08AM6,O60220,Q99720,Q9NQZ5,P35637 5 +Abnormal autonomic nervous system physiology 0.3639585118252536 1.0324624269665277 0.3018555403946117 1.0 0.8687830497574704 32 P06280,P07602,P0DP25,Q9NZJ7,P42892,P04062 6 +Aplasia of the proximal phalanges of the hand 0.7778143515470427 1.032219007844934 0.301969532558356 1.0 0.8687830497574704 2 Q08AM6 1 +Aplasia of metacarpal bones 0.7778143515470427 1.032219007844934 0.301969532558356 1.0 0.8687830497574704 2 Q08AM6 1 +Partial absence of thumb 0.7778143515470427 1.032219007844934 0.301969532558356 1.0 0.8687830497574704 2 Q08AM6 1 +Delayed closure of the anterior fontanelle 0.4553519877575018 1.0314317250549725 0.302338409968121 1.0 0.8687830497574704 12 P51812,Q9Y487,P40855 3 +Sensory axonal neuropathy 0.4275639030258968 1.030642417707345 0.3027085367917324 1.0 0.8687830497574704 15 O95140,P09651,P22626,Q96RR1,Q15067,O95831,Q8IV08 7 +Abnormal large intestine physiology 0.4151161653558327 1.0296370493898457 0.3031804164317204 1.0 0.868934855082888 17 P07602,Q9NZJ7,P21964 3 +Flared metaphysis 0.4709744647070858 1.0292727268866102 0.3033515354688014 1.0 0.868934855082888 11 Q08AM6,Q86WC4,Q14739,Q96HY6 4 +Ascending tubular aorta aneurysm 0.58202595322284 1.02777107532064 0.3040575252955131 1.0 0.868934855082888 5 O75844 1 +Generalized hyperkeratosis 0.6905383492487707 1.0252785409978742 0.3052317781344285 1.0 0.868934855082888 4 O75844,P21912 2 +Abnormal anatomic location of the heart 0.5075580654430187 1.0229678565232765 0.3063230439106554 1.0 0.868934855082888 9 O75844 1 +Narrow mouth 0.3239181957273407 1.0198987296185031 0.3077764921125561 1.0 0.868934855082888 65 Q9Y487,P55201,P16435,Q9Y619,P04062,Q15392,Q8NCH0,P21964,O75844,Q7LGA3 10 +Abnormal caudate nucleus morphology 0.4534864023942722 1.0194058462230997 0.3080103318222229 1.0 0.868934855082888 12 O75306,Q13057,O60220,Q96RL7,P00846 5 +Abnormal ovarian physiology 0.395692144404907 1.0164879293354734 0.3093970926585028 1.0 0.868934855082888 21 P49770,Q9NR50,Q96RR1,Q15031,P57740,Q05655,Q06787,O75844 8 +Acute coronary syndrome 0.406459266220739 1.0142125663678514 0.3104813336302872 1.0 0.868934855082888 18 Q9NZ08,O75844,Q9Y4P3 3 +Symptomatic seizures 0.5059455600706242 1.0139782857358586 0.3105931137315401 1.0 0.868934855082888 9 P31751,P40939,O43826,Q16836,Q13423 5 +Skin dimple 0.377575379029706 1.0110585812493529 0.3119883925639028 1.0 0.869086898384567 25 Q5H8A4,Q15125,P53701,O96028,O95202,Q9Y4P3,P61978,O43909,P49366,Q9UM00 10 +Adrenal insufficiency 0.3821978888228564 1.0108204016924438 0.3121023966339264 1.0 0.869086898384567 24 P40855,O95470,P16435,Q9Y5Y5,Q13423,O75381 6 +Abnormal visual field test 0.7859232174372266 1.010241064533686 0.3123798095551788 1.0 0.869086898384567 3 P00846 1 +Abnormality of subcutaneous fat tissue 0.4302631755178654 1.0100226847114813 0.31248442187194 1.0 0.869086898384567 14 Q9Y487,O75844 2 +Delayed epiphyseal ossification 0.6866855111755735 1.0092691578463868 0.3128455673544557 1.0 0.869086898384567 4 Q9UG56,Q96HY6 2 +Increased c peptide level 0.7722185648452711 1.0090634346706262 0.3129442127738726 1.0 0.869086898384567 2 Q16836 1 +Abnormally folded helix 0.4184251025519689 1.0080001649117123 0.3134543830628979 1.0 0.869086898384567 16 P21964 1 +Osteopenia 0.3192250502459046 1.0071151120651376 0.3138794598411338 1.0 0.869086898384567 68 Q9Y5U9,O75718,Q96L58,P07602,Q9NZJ7,O00754,Q9Y487,Q9Y4P3,Q14108,Q13277,Q13126,P07237,P04062,O43826,Q5JRA6,O75844,Q9NWM8 17 +Sensory ataxia 0.5774201324067495 1.0062814176023005 0.3142802167107557 1.0 0.8691464225836115 5 Q96RR1,P54802 2 +Long fingers 0.3072050700000387 1.0040727324554124 0.3153435574104293 1.0 0.8693926319151776 76 Q15907,Q9UHX1,Q5H8A4,Q08AM6,P51812,P23786,P16435,P42892,Q9BV10,P21964,Q8NCH0 11 +Muscle fiber atrophy 0.3978341536379285 1.0028488711138266 0.3159337848958317 1.0 0.8699653677307132 20 Q99720,P23786,Q9BTV4,Q96RL7,P50402,P22626,P35637 7 +Abnormal femoral neck morphology 0.3512115014175073 1.0015705982324357 0.3165510271664622 1.0 0.8710066128620411 36 Q96A33,P51812,O75718,Q96L58,P16278,Q96HY6,P04066,Q9Y487,O00754,O75431,Q9Y619,O43909,P50542,O95831,O75844,Q9H9E3,P55011 17 +Abnormality of temperature regulation 0.3053621278516313 1.0008674728814588 0.316890883864833 1.0 0.871019112206118 91 Q9HC21,P07602,Q9NZJ7,P23786,P10253,P00846,Q15645,P06280,P51572,Q13510,Q9BW27,Q8N1F7,P03886,P35610,P28070,Q8NFH4,P10644,Q9NZ08,Q9HC07,P49770,Q9NR50,Q05655,Q14739,Q5XKP0 24 +Hepatosplenomegaly 0.3531505563578996 0.9958165998944392 0.3193392632496179 1.0 0.8739185852569958 35 Q96HY6,P16278,Q9UJS0,O00754,Q05655,P04062,P10619,Q13510,Q14739,Q9H9E3 10 +Chronic otitis media 0.3885863028614126 0.991933537663279 0.3212299476699907 1.0 0.8739185852569958 22 Q5H8A4,Q05655,Q9Y4P3,P21964 4 +Abnormality of the gingiva 0.3336995201773002 0.9913445061526132 0.3215173877304187 1.0 0.8739185852569958 50 Q08AM6,Q9Y5U9,P16278,O00754,Q9Y4P3,Q14108,Q96S52,P10644,Q86WC4,O43909,O43826,Q15392,P04062,Q14739,P53634,Q5JRA6,P08236 17 +Abnormal sella turcica morphology 0.5224598500422111 0.9892772366726622 0.3225275181770572 1.0 0.8739185852569958 8 O00754,P16278,P08236 3 +Abnormality of endocrine pancreas physiology 0.573697911185803 0.9889316083538798 0.3226966044105981 1.0 0.8739185852569958 5 Q14739 1 +Pancreatic islet cell hyperplasia 0.7802025989349705 0.9882213786102628 0.323044240219416 1.0 0.8739185852569958 3 Q14739 1 +Heart block 0.3793980241998833 0.9872362911735592 0.323526814532749 1.0 0.8739185852569958 24 P06280,Q9HD47,P0DP25,P23786,P46976 5 +Progressive cerebellar ataxia 0.3495974792598055 0.9855544578912312 0.3243517956052348 1.0 0.8739185852569958 36 Q9P0J0,Q96CU9,Q9Y487,Q9Y619,Q7KZN9,O14773,P35637 7 +Progressive 0.3163533774252792 0.9845595958326664 0.3248404444223132 1.0 0.8739185852569958 109 Q13057,Q99720,Q8N183,Q13126,P57740,Q9NRG9,P28288,Q08AM6,Q9GZY8,Q9UHD9,O95470,Q96RR1,P12235,P04350,Q96RL7,O00400,P04062,Q9BW27,Q13510,Q9NR28,Q9Y3E5,Q8N1F7,Q16637,P15586,Q8N766,O60313,O14653,P56192,P27544,Q96D71,O00429,O94905,O75569,Q12769,O60762,Q9NP80,Q14671,Q9Y5Y5,O95831,Q5XKP0,P54802 41 +Respiratory arrest 0.5379268942848168 0.9803266800710888 0.326924888984337 1.0 0.875862641485916 6 P23786 1 +Agenesis of corpus callosum 0.3003330576803543 0.979854676873067 0.3271578580173031 1.0 0.875862641485916 79 O43505,Q9UHX1,Q5H8A4,Q9HC21,Q13409,P23786,O60566,Q15392,Q10713,Q08AM6,Q9BXW9,P53701,Q969G3,P03886,O96028,P61978,Q86WC4,Q86XL3,Q7LGA3,O95202,O43175,Q15042,P55011 23 +Abnormality of female external genitalia 0.3514929355104397 0.9795886016897952 0.3272892336065904 1.0 0.875862641485916 35 Q08AM6,P40855,P53701,P16435,Q9Y619,Q6NUK1,P10644,Q15392,Q9Y5Y5,O75381 10 +Thoracic hypoplasia 0.3690489876692953 0.9787888601682828 0.327684315053447 1.0 0.875862641485916 26 Q96A33,Q9UHX1,Q14739,P16435 4 +Scanning speech 0.7775869850199322 0.9781730698985036 0.3279887333044942 1.0 0.875862641485916 3 O14773 1 +Craniofacial asymmetry 0.7646477946017125 0.977862138073636 0.3281425133192921 1.0 0.875862641485916 2 O95202 1 +Leukoencephalopathy 0.3023400216668757 0.9775841929867484 0.3282800184070096 1.0 0.875862641485916 89 Q9UHX1,Q96BR5,Q86Y39,P07602,Q9NZJ7,O96000,Q9BUB7,Q53FT3,P17900,O75503,P03886,P51571,O60313,O43676,O00429,O75306,Q9NPL8,P49770,Q96CU9,Q9NR50,O95202,Q01105 22 +Thick eyebrow 0.3376056505371321 0.976078171342851 0.3290257277054147 1.0 0.877012811152712 40 Q9UHX1,P51812,Q03164,P04066,O00754,Q969G3,P15586,Q6NUK1,O94905,Q9BSJ2,Q9UM00,P08236 12 +Pelvic kidney 0.4989202833378361 0.9748150659375766 0.3296520024515248 1.0 0.8772974200210477 9 Q9UHX1 1 +Hypoplastic fingernail 0.4303506554229016 0.9747314350078178 0.3296934956958766 1.0 0.8772974200210477 13 P51812,O60826,O75431,Q969G3,Q14739,P48651 6 +Ectopia lentis 0.5705501460620783 0.9742729945712196 0.3299210096873732 1.0 0.8772974200210477 5 Q03518 1 +Fatigable weakness of respiratory muscles 0.4250246839350949 0.973883760996888 0.3301142576057159 1.0 0.8772974200210477 14 Q92804,Q15165,P35637 3 +Pigmentary retinopathy 0.333807187703165 0.9735225900900184 0.3302936384168535 1.0 0.8772974200210477 45 Q9P0J0,O75306,P03886,P21912,O76024,Q96CU9,P53701,Q9UG56,Q15067,Q15555,Q7KZN9,P00846,Q16836 13 +Abnormal cardiac ventricular function 0.4074467966676413 0.9729757262428426 0.3305653664119536 1.0 0.8772974200210477 17 P03886,Q96RR1,P12235,P10253,O75844 5 +Urticaria 0.4985029006747814 0.9724886535564484 0.3308075068924161 1.0 0.8772974200210477 9 P51648 1 +Abnormal oral mucosa morphology 0.3240623024206074 0.9695073244423688 0.3322921275517831 1.0 0.8781016836920442 61 Q14108,O43909,O43826,Q15392,Q5JRA6,P08236,Q08AM6,P16278,P04062,P53634,Q9UM00,Q9Y5U9,O00754,Q9Y4P3,P10644,Q86WC4,Q9NZ08,Q96S52,Q05655,Q14739 20 +Patent ductus arteriosus 0.2967136260612413 0.9694308755570455 0.332330253527654 1.0 0.8781016836920442 82 Q6ZXV5,Q9UHX1,P40855,P0DP25,Q9Y4P3,P42892,Q6NUK1,Q9BV10,Q15392,P21964,O75844,Q9NWM8 12 +Distal arthrogryposis 0.5691732065623711 0.9678650673800088 0.3331117624536914 1.0 0.8781016836920442 5 Q8NCH0 1 +Abnormal tongue morphology 0.3159896596992447 0.9655173127444664 0.3342857687693528 1.0 0.8781016836920442 68 P10253,Q10713,Q08AM6,Q96A33,P16278,Q6NUK1,Q96RL7,P21912,O75844,O43924,P04066,O00754,O75431,Q9Y4P3,P61978,O94905,Q7LGA3,Q96S52,Q9Y5Y5,Q15042 20 +Oligomenorrhea 0.6758893280632411 0.9645221435644378 0.3347842120782403 1.0 0.8781016836920442 4 Q15031,P31751,Q9UNE7 3 +Delayed fine motor development 0.4968902833603599 0.963500832989478 0.3352962463339373 1.0 0.8781016836920442 9 P51798,P16435,O60508,O75175,Q5KU26 5 +Spastic gait 0.3927142174475022 0.962755489063689 0.3356702428475975 1.0 0.8785753364290685 20 Q9Y619,O00400,Q9NVI7,O94905 4 +Limited wrist movement 0.5677643484945502 0.9613114329718058 0.3363956010566706 1.0 0.8797053652451976 5 O75844 1 +Abnormal labia morphology 0.4055235253514571 0.9587645042026252 0.3376773947304672 1.0 0.8809196906425508 17 Q9Y619,Q08AM6,P16435 3 +Generalized hyperpigmentation 0.4959555870021866 0.9582918634775518 0.3379156055410632 1.0 0.8809196906425508 9 P51648 1 +Ectopic anus 0.443939888870943 0.9578568285500326 0.3381349584176081 1.0 0.8809713206424394 12 Q6NUK1,P16435 2 +Oligosacchariduria 0.5323624061905523 0.9525161496918146 0.3408352795412588 1.0 0.8840079344228056 6 P04066,O00754,P10253,P16278 4 +Abnormal circulating albumin concentration 0.3593258110347535 0.9516362957783696 0.3412814673519699 1.0 0.8840079344228056 30 Q9UJS0,Q9BT22,O95470,Q5XKP0,Q12769,Q8NFH4,Q9BV10,Q9BW27,Q8N1F7 9 +Rigidity 0.3277942819050966 0.9486427919724646 0.3428023191592269 1.0 0.8840079344228056 54 Q86SQ9,Q9H6K4,P07602,Q96CU9,Q9NZJ7,P12235,P04062,Q15392,P00846 9 +Multifocal cerebral white matter abnormalities 0.5650237548041301 0.9485715606793264 0.3428385609571704 1.0 0.8840079344228056 5 Q9Y619 1 +Vegetative state 0.7692787549483515 0.946344077996318 0.3439731183046466 1.0 0.8840079344228056 3 Q9NZJ7 1 +Progressive peripheral neuropathy 0.7692787549483515 0.946344077996318 0.3439731183046466 1.0 0.8840079344228056 3 Q9NZJ7 1 +Resting tremor 0.3940184466790012 0.945297633331501 0.3445069463427632 1.0 0.8840079344228056 19 Q9NZJ7,P04062,P12235,Q9H6K4 4 +Nuclear cataract 0.5643019978319209 0.9452183992474188 0.3445473879383676 1.0 0.8840079344228056 5 P08670,O76024 2 +Abnormal bleeding 0.3007934290824735 0.9448355957919258 0.3447428159960115 1.0 0.8840107496989045 90 Q6ZXV5,Q9UHX1,P38435,P11117,Q9Y487,P23786,Q14108,Q13126,Q05655,Q14739,Q8NCH0,P04062,P21964,Q9NZ08,O75844,Q9NWM8,P05067 17 +Easy fatigability 0.3937612876412286 0.9433177669352684 0.3455183908145134 1.0 0.8842469798691696 19 Q53H12,Q96RR1,P12235,P10644,P21912,Q9NWM8 6 +Heterogeneous 0.3308235104963146 0.9389163310854274 0.3477737037160493 1.0 0.8842469798691696 44 P03886,Q9BQE5,P12235,Q9Y619,P00846,P21964,O75844,P05067 8 +Hyperintensity of cerebral white matter on mri 0.4027422159669265 0.938214484072692 0.3481341963712008 1.0 0.8842469798691696 17 P07602,P17900,Q9NZJ7,O75503 4 +Retrocollis 0.7667141120756807 0.936547751533678 0.3489912387595408 1.0 0.8842469798691696 3 Q99720 1 +Anteriorly placed anus 0.4702108200799533 0.9340378387026088 0.3502843748320359 1.0 0.8842469798691696 10 Q6NUK1,P16435 2 +Inability to walk 0.2992583723625631 0.9328366175966298 0.3509043317676066 1.0 0.8842469798691696 89 Q13409,O60220,Q99720,Q96N66,O43909,P00846,Q9BTW9,P35637,Q08AM6,O14949,Q9GZY8,Q96RR1,P12235,O15269,Q13510,P21912,Q9NVI7,O75503,O00429,O94905,Q15041,Q96CU9 22 +Abnormal heart rate variability 0.6677956228332518 0.9311033006350916 0.3518001314320151 1.0 0.8842469798691696 4 Q9NZJ7 1 +Memory impairment 0.3509464620080726 0.9298105671494372 0.352469174089868 1.0 0.8842469798691696 33 P03886,P49770,Q9NR50,P07602,Q9NZJ7,Q96RR1,O96008,Q969G3,Q9NZ08,P05067 10 +Pseudoepiphyses of the metacarpals 0.7648995719459886 0.929625333778633 0.3525651058788384 1.0 0.8842469798691696 3 P51812,O95202 2 +Hypoplastic pubic rami 0.7648995719459863 0.9296253337786244 0.3525651058788428 1.0 0.8842469798691696 3 Q5H8A4,O95202 2 +Aplasia hypoplasia of the pubic bone 0.7648995719459863 0.9296253337786244 0.3525651058788428 1.0 0.8842469798691696 3 Q5H8A4,O95202 2 +Rib segmentation abnormalities 0.7648995719459863 0.9296253337786244 0.3525651058788428 1.0 0.8842469798691696 3 Q5H8A4,O95202 2 +Abnormality of abdominal situs 0.7648995719459863 0.9296253337786244 0.3525651058788428 1.0 0.8842469798691696 3 Q5H8A4,O95202 2 +Malrotation of small bowel 0.7648995719459849 0.9296253337786192 0.3525651058788455 1.0 0.8842469798691696 3 O95202,Q8NCH0 2 +Decreased circulating cortisol level 0.5146235320332809 0.9284724299940684 0.3531625625690573 1.0 0.8842469798691696 7 Q13423,Q969G3,P16435 3 +Proptosis 0.3287007189279822 0.9264578525793752 0.3542080908432354 1.0 0.8843537899263875 48 Q5H8A4,Q13409,O75718,Q96L58,O43909,Q08AM6,Q9BXW9,Q969G3,P16435,Q6NUK1,P07237,O75844,O00754,Q9NX62,O75431,O96028,P61978,Q9H9E3,O95202 19 +Decreased proportion of cd4 positive helper t cells 0.5270015745742375 0.9257594133383594 0.3545710238396728 1.0 0.8844950722033861 6 Q05655,Q9H0U3 2 +Quadriceps muscle weakness 0.6660970784415087 0.9241056694094538 0.3554313018218926 1.0 0.8844950722033861 4 Q96RR1,P12235 2 +Increased circulating antibody level 0.406543883128965 0.9222737192134458 0.3563858187519815 1.0 0.8845128483071092 16 P28070,Q05655,P04062 3 +Increased susceptibility to fractures 0.3274927360228215 0.9214057091311576 0.3568386491886675 1.0 0.8845128483071092 50 Q9Y5U9,O75718,Q96L58,P22626,O60220,P16435,Q14108,Q13126,P07237,O15269,O43826,P04062,Q14739,Q9BTW9 14 +Abnormal circulating pyruvate family amino acid concentration 0.3874258388054294 0.9213425371857562 0.3568716193783627 1.0 0.8845128483071092 20 Q9P0J0,P03886,O96000,Q9BUB7,Q9NP80,P00846,Q5XKP0 7 +Optic nerve dysplasia 0.7508229098090771 0.9213082125707588 0.3568895346078302 1.0 0.8845128483071092 2 O43505 1 +Telangiectasia 0.3499937912387546 0.9207202587594832 0.3571964964436538 1.0 0.8845128483071092 33 O75306,P03886,Q8IZA0,P06280,P10619,O43826,P00846,P21912,Q14739 9 +Aplasia hypoplasia of the proximal phalanges of the hand 0.761936121172197 0.9183358426158648 0.3584430679444923 1.0 0.8845128483071092 3 Q08AM6,Q9BXW9 2 +Prominent sternum 0.7498354180381623 0.9172915081843188 0.3589899060128538 1.0 0.8845128483071092 2 P16278 1 +Stenosis of the external auditory canal 0.5249141941681399 0.9153521357202162 0.3600067973146865 1.0 0.8845931853637032 6 O95202,P55011,P16435 3 +Spastic diplegia 0.3706964551897795 0.9139195501212792 0.3607591201036797 1.0 0.8846863813216382 24 P07602,P51648,Q9NZJ7,Q99720 4 +Laryngeal dystonia 0.7593019427066201 0.908317916571628 0.3637102792160953 1.0 0.8880058817383937 3 Q96RL7,P04350 2 +Abnormal placenta morphology 0.5070717489681353 0.9082849919257202 0.3637276697212153 1.0 0.8880058817383937 8 O75844 1 +Parkinsonism with favorable response to dopaminergic medication 0.4657522175327995 0.9076612831433556 0.3640572053901465 1.0 0.8880058817383937 10 Q9NZJ7,P04062 2 +Bradycardia 0.4510213487980083 0.9061703786687312 0.3648456788237102 1.0 0.8880058817383937 11 O43464,P0DP25,Q96RR1,O75880 4 +Gowers sign 0.419755418959128 0.9031965210283358 0.3664216039586165 1.0 0.8894620471759588 13 Q13510,Q9NP80 2 +Dysmetria 0.3230397478609895 0.9006981823001065 0.3677488154106174 1.0 0.8914703561001119 55 Q6DKK2,Q9NPL8,Q96BR5,O60313,Q6P4A7,Q9Y4P3,Q5JRX3,O75027,Q9NP80,Q10713,O14773,Q8IV08,O75503 13 +Weakness due to upper motor neuron dysfunction 0.322085793093211 0.8997960490329149 0.3682287973427369 1.0 0.8914703561001119 128 Q6DKK2,Q96L58,P07602,Q9NZJ7,P00846,Q7KZN9,Q9BTW9,P35637,Q9P0J0,Q9H6K4,P17900,P51572,Q969G3,O00400,P04062,Q13510,P21912,Q9UBX3,P50416,P03886,O60313,O00754,P56192,Q9Y619,O00429,O94905,Q9NZ08,O75306,Q96CU9,Q9NP80,Q9Y5Y5,Q5XKP0,Q13423 33 +Abnormal endocardium morphology 0.4088801612402172 0.8988974494626502 0.3687072866535239 1.0 0.8919059741032124 15 Q9NZ08,P04062,Q9Y4P3 3 +Delayed menarche 0.5212545418489252 0.8971228602074507 0.3696533615829258 1.0 0.8919059741032124 6 O75844,O00429 2 +Limited hip movement 0.4343539457809985 0.8960830415168598 0.3702084136110608 1.0 0.8919059741032124 12 O75844 1 +Hyperthyroidism 0.504678149553643 0.8957052009768092 0.3704102319060522 1.0 0.8919059741032124 8 P21964 1 +Polar cataract 0.7552389710797218 0.8928992048226384 0.3719111529931527 1.0 0.8919059741032124 3 Q7LGA3 1 +Joint laxity 0.3077294066603031 0.8916113237916927 0.3726012984897824 1.0 0.8919059741032124 70 Q9HC07,Q96A33,Q9UHX1,Q5H8A4,Q96L58,P16278,Q96HY6,Q9Y4P3,Q9Y619,Q8NCH0,Q9Y487 11 +Pseudoepiphyses of hand bones 0.6581535535738663 0.8914597088402851 0.3726825975901691 1.0 0.8919059741032124 4 P51812,O95202 2 +Pseudoepiphyses 0.6581535535738663 0.8914597088402851 0.3726825975901691 1.0 0.8919059741032124 4 P51812,O95202 2 +Abnormal circulating arginine concentration 0.7432521395655047 0.8905981237286645 0.373144806152081 1.0 0.8919059741032124 2 Q9UJS0 1 +Insidious onset 0.5523604909547261 0.8898772014826624 0.3735318269312331 1.0 0.8919059741032124 5 P04062 1 +Irregular capital femoral epiphysis 0.7429229756418707 0.8892674364039981 0.3738593678384654 1.0 0.8919059741032124 2 P50542 1 +Abnormal metabolic brain imaging by mrs 0.4018732462539996 0.8885926414909634 0.3742220472022128 1.0 0.8919059741032124 16 O75306,P03886,P07602,Q9NZJ7,O00429,P21912 6 +Abnormal atrioventricular valve morphology 0.3465480437263258 0.8878397531508136 0.3746269558845325 1.0 0.8919059741032124 33 P51812,Q96L58,P55795,Q9Y4P3,P04062,P21964,O75844 7 +Elevated circulating follicle stimulating hormone level 0.6562944289954833 0.8838393179753183 0.37678295838214 1.0 0.8919059741032124 4 Q8IY37,P16435 2 +Aplasia hypoplasia of the optic nerve 0.379017030415868 0.8836179320868026 0.3769024956020184 1.0 0.8919059741032124 21 Q9UHX1,P07196,P61978,Q96KP1,O95721,O14936,Q9NVI7,P37268,P30153,Q9H3S7 10 +Distal sensory loss of all modalities 0.6555921623594484 0.8809628896844798 0.3783379063201946 1.0 0.8924420002230805 4 O15269,O15270 2 +Hypoplasia of the odontoid process 0.5052065988165998 0.8798473689692724 0.3789419996006535 1.0 0.8930712108701295 7 O43909,Q9H9E3,P16278,P08236 4 +Punctate cataract 0.6551657440465498 0.879216885293489 0.3792836908420787 1.0 0.8930712108701295 4 Q9H6K4 1 +Congenital nystagmus 0.3945958747567718 0.8780548539819115 0.3799139512136091 1.0 0.8934033893189597 17 P00846 1 +Status epilepticus with prominent motor symptoms 0.7510701350016311 0.87712223364293 0.3804202495058482 1.0 0.8934033893189597 3 Q96RR1,Q13510 2 +Abnormal periventricular white matter morphology 0.3386525868491509 0.8768481778424553 0.3805691069143933 1.0 0.8934033893189597 36 Q53FT3,Q9UHX1,P07602,O60313,P17900,Q9NZJ7,P51571,O00429,O75503 9 +Optic nerve hypoplasia 0.3942568089235267 0.8755525299701737 0.381273341301884 1.0 0.893566424308228 17 Q9UHX1,P07196,P61978,O14936,Q9NVI7,P37268 6 +Proximal tubulopathy 0.370026908046454 0.8734029656731691 0.382443475106728 1.0 0.894099091374286 23 O75306,P03886,Q96CU9,Q86Y39,O96000,O43676 6 +Metaphyseal cupping 0.7500823180770355 0.8733905342719162 0.3824502486432819 1.0 0.894099091374286 3 Q14739,P50542 2 +Infantile spasms 0.3489400512136667 0.8729224751236395 0.3827053350091454 1.0 0.894099091374286 31 Q13510,Q9UBX3,P00846 3 +Decreased circulating aldosterone level 0.7386438446345991 0.8720044834848957 0.3832059316456599 1.0 0.894099091374286 2 Q13423 1 +Aplasia cutis congenita of scalp 0.5484650132920956 0.8718878548636597 0.3832695599428133 1.0 0.894099091374286 5 Q5H8A4,O95202 2 +Craniosynostosis 0.3403533151266238 0.8704487431983138 0.3840552189200492 1.0 0.8954726759955428 35 Q96L58,Q9NX62,P16435,Q9Y619,Q6NUK1,P07237,O43909,P21964,Q8NCH0 9 +Perisylvian polymicrogyria 0.5476330019140814 0.8680501999205099 0.3853668518237454 1.0 0.8956243111151724 5 Q15042 1 +Micropenis 0.3137163785411813 0.8661559872510992 0.3864046257848093 1.0 0.8956243111151724 63 O43505,Q08AM6,Q86SQ9,O95470,P16435,P42892,Q9Y619,Q6NUK1,Q10713,Q9BV10,P46977 11 +Abnormal circulating proteinogenic amino acid derivative concentration 0.3727673338778784 0.8636027249519613 0.3878061667253203 1.0 0.8956243111151724 22 Q9P0J0,P03886,O96000,Q9BUB7,Q9NP80,P00846,Q5XKP0 7 +Basal ganglia calcification 0.5144963618381003 0.8635241280615398 0.387849359355719 1.0 0.8956243111151724 6 O60313,P03886 2 +Abnormal tricuspid valve morphology 0.4436063553988185 0.8604873794907089 0.3895204374487446 1.0 0.8983570884281824 11 P51812,P21964 2 +Vertebral segmentation defect 0.3537371689529653 0.8565840091002106 0.3916748263134513 1.0 0.8984534453300982 27 Q9Y619,Q9UHX1,P16435 3 +Decreased circulating follicle stimulating hormone concentration 0.7346938775510214 0.8561306612391133 0.3919255106284565 1.0 0.8984534453300982 2 Q969G3 1 +Slurred speech 0.500352273788177 0.8548370958052018 0.3926413386054594 1.0 0.8984534453300982 7 Q96RL7,Q9Y487,P16278 3 +Hypoketotic hypoglycemia 0.4968097936370455 0.8544054317822226 0.3928803873430397 1.0 0.8985484575281488 8 Q16836,P50416,P23786,P40939 4 +Arm dystonia 0.6487588431528624 0.8530372925316424 0.3936386239084084 1.0 0.8998302010851005 4 Q99720 1 +Impaired antigen specific response 0.4959614706337381 0.8499583576886253 0.3953482385214957 1.0 0.9009024051186724 8 Q05655,Q9BV10 2 +Cupped ear 0.4559220983489099 0.8495783072919881 0.3955595766599946 1.0 0.9009024051186724 10 Q15392 1 +Abnormal sternum morphology 0.3037754060857427 0.8491949922512574 0.3957727993296196 1.0 0.9009024051186724 104 Q9UHX1,O75718,Q96L58,P55795,Q9BTV4,O43909,O60566,P50402,Q9BTW9,P08236,Q08AM6,Q96A33,P16278,P04062,Q13510,P21912,Q8NCH0,Q9NVI7,O00754,O96028,O75431,Q9Y4P3,P61978,Q9Y619,Q15555,Q9Y487,Q9H9E3,Q7LGA3,P51812,Q03164,O95202,Q96S52,Q14739,Q06787,P55011 35 +Abnormal circulating tyrosine concentration 0.7434968719130672 0.8485811846179884 0.3961143802913833 1.0 0.9009024051186724 3 P16930,Q9UJS0 2 +Abnormality of bladder morphology 0.4556412232775529 0.8479206360760111 0.3964821711482353 1.0 0.9009024051186724 10 Q9Y4P3,P16435 2 +Mutism 0.4114140355983599 0.8469562549278689 0.3970195048259648 1.0 0.9009024051186724 13 P53701,Q13510,P35637 3 +Atrophy degeneration affecting the brainstem 0.4549796372857981 0.8440165894013693 0.3986601354717467 1.0 0.9009024051186724 10 O60313,Q96RR1,O00429,Q9BTW9 4 +Cerebral hypomyelination 0.4061809690013308 0.8439990700370531 0.3986699252699184 1.0 0.9009024051186724 14 P49770,Q9NR50,P51572,P04350,P00387,Q9BTW9 6 +Coombs positive hemolytic anemia 0.7314022383146499 0.8429492735140872 0.3992568144029993 1.0 0.9009024051186724 2 Q05655 1 +Increased b cell count 0.7314022383146499 0.8429492735140872 0.3992568144029993 1.0 0.9009024051186724 2 Q05655 1 +Abnormal proportion of double negative alpha beta regulatory t cell 0.7314022383146499 0.8429492735140872 0.3992568144029993 1.0 0.9009024051186724 2 Q05655 1 +Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells 0.7314022383146499 0.8429492735140872 0.3992568144029993 1.0 0.9009024051186724 2 Q05655 1 +Follicular hyperplasia 0.7314022383146499 0.8429492735140872 0.3992568144029993 1.0 0.9009024051186724 2 Q05655 1 +Burkitt lymphoma 0.7314022383146499 0.8429492735140872 0.3992568144029993 1.0 0.9009024051186724 2 Q05655 1 +Macrogyria 0.5100105614325715 0.8412759569997288 0.4001933566737599 1.0 0.902120703423654 6 O43505,O43175,Q15392 3 +Pericardial effusion 0.644995808919783 0.837710689595187 0.4021932083789195 1.0 0.9048352645478264 4 P04062 1 +Abnormal shape of the frontal region 0.2961704075440971 0.8368549518972168 0.4026741044983462 1.0 0.9048984685448246 94 Q5H8A4,Q96L58,O43909,O60566,Q15392,Q15645,Q9BTW9,Q9P2J5,Q9BXW9,P16278,P16435,P07237,P13073,Q9NVI7,P15586,O43924,Q4J6C6,P04066,Q15125,O00754,O96028,O75431,Q15067,Q9Y619,P42345,Q9Y487,Q9H9E3,P51812,O95202,Q13045,Q14739,P50542 32 +Delayed ability to walk 0.3122088389631975 0.8359206506332015 0.4031995441259404 1.0 0.9048984685448246 62 Q6ZXV5,Q15907,Q5H8A4,Q13409,Q3ZCQ8,Q99720,Q96N66,P55201,Q01105,O60783,Q10713,O94905,P21912,Q10471,Q15042,P55011,P35637 17 +Gliosis 0.3242205308341066 0.8351750664277828 0.4036191461112075 1.0 0.9048984685448246 40 O75306,P49770,Q9UHD9,Q9NR50,P04062,Q10713,Q7KZN9,P00846,Q9BTW9,P35637 10 +Mild postnatal growth retardation 0.7290980908492439 0.8337484887507832 0.4044227279352368 1.0 0.9048984685448246 2 P10644 1 +Abnormal umbilicus morphology 0.318401112395408 0.8281609991132821 0.4075793278022357 1.0 0.9048984685448246 52 Q9Y487,Q9Y4P3,Q6NUK1,Q14739,P21964,Q8NCH0,O75844,P08236 8 +Abnormal renal cortex morphology 0.3167950344542659 0.8278251439112979 0.4077695328146677 1.0 0.9048984685448246 55 Q14108,P57740,O43826,P00846,P06280,O95470,Q16134,P49327,Q9BW27,P21912,Q8N1F7,P03886,Q8NFH4,O75431,P16930,Q86WC4,Q9NZ08,Q12769,Q02978,Q05655 20 +Abnormality of the biliary system 0.3002040275358242 0.8262032983366583 0.4086887775335459 1.0 0.9048984685448246 101 Q5H8A4,Q96A33,P40855,P07602,P09601,Q9NZJ7,Q9Y4P3,Q14108,Q14739,P04062,Q13510,P21964,P00374,Q10713,Q5XKP0,O75381,O15118 17 +Motor seizure 0.3001441205236413 0.8253311884145934 0.4091835897552658 1.0 0.9048984685448246 101 Q86SQ9,P07602,Q9NZJ7,Q96N66,O43909,O60566,P00846,Q9BTW9,Q9NZ01,P16278,Q9GZY8,P04062,Q13510,P21912,P13073,Q9UBX3,O75503,Q9Y5U9,P03886,O14653,Q9Y619,O00429,O60762,Q01105,Q9Y320,Q9UBB4,Q5XKP0 27 +Anencephaly 0.4078281205655444 0.8228162004184615 0.4106125225474752 1.0 0.9065192293980472 13 Q08AM6,P21964 2 +Oval face 0.4933603256194103 0.8188967095912214 0.4128453473982576 1.0 0.9089332127439528 7 Q9UHX1 1 +Cachexia 0.392188395109159 0.8188559330574083 0.4128686144017286 1.0 0.9089332127439528 16 P07602,Q9NZJ7,P04062,Q99720 4 +Abnormality of the scrotum 0.3197127705994216 0.8180794636278158 0.4133118144413241 1.0 0.9089332127439528 44 Q9Y5U9,P16435,Q9Y619,Q6NUK1,Q9BV10,Q7LGA3 6 +Fetal ultrasound soft marker 0.4022858890756942 0.8172153319754395 0.4138053821922898 1.0 0.9089332127439528 14 P40855,Q15125,P61978,P16435,Q9Y5Y5,O75381 6 +T lymphocytopenia 0.489066923325176 0.8138647939068806 0.4157224112924402 1.0 0.9090050554896494 8 Q05655,Q9H0U3 2 +Abnormal spermatogenesis 0.4214981061113566 0.8134118471487572 0.4159819691337501 1.0 0.9090050554896494 12 P04062,P16435 2 +Ecchymosis 0.4495544814480791 0.8120322062836204 0.4167731515656623 1.0 0.9090050554896494 10 P04062,Q8NCH0 2 +Multicystic kidney dysplasia 0.3856375270715557 0.8120140139388109 0.416783590252288 1.0 0.9090050554896494 17 P40855,O60566,Q10713,Q9Y5Y5,O75381 5 +Thickened nuchal skin fold 0.4495303922770935 0.8118903157791494 0.4168545717956062 1.0 0.9090050554896494 10 P40855,Q15125,P61978,Q9Y5Y5,O75381 5 +Prenatal maternal abnormality 0.421214272270062 0.8115901897396443 0.4170268223356652 1.0 0.9090050554896494 12 P49366,P50416,Q14739,P16435 4 +Hyperextensibility of the finger joints 0.6382315662893887 0.8102607376592404 0.4177903357812895 1.0 0.9090050554896494 4 Q5H8A4 1 +Abnormality of hand joint mobility 0.6382315662893887 0.8102607376592404 0.4177903357812895 1.0 0.9090050554896494 4 Q5H8A4 1 +Progressive hearing impairment 0.4010963469770524 0.8090427878254182 0.418490535003488 1.0 0.9090050554896494 14 O60313,P03886,O76024,O60220 4 +Hypoglycemic coma 0.4880972579184771 0.8087961989538776 0.4186323829571705 1.0 0.9090050554896494 8 P31751,Q16134,P40939,Q16836,Q13423 5 +Aphthous ulcer 0.4913231591941753 0.8084462769661325 0.4188337208850967 1.0 0.9090050554896494 7 Q9NZ08 1 +Bacterial endocarditis 0.7326452887900268 0.8079794648932802 0.4191024036537309 1.0 0.9091544273823664 3 P04062 1 +Bilateral cryptorchidism 0.4487196112447164 0.8071153607211218 0.4196000230676282 1.0 0.909350124651722 10 O43924,P36543,P37268 3 +Bilateral tonic clonic seizure 0.2847606427462609 0.8059139800322229 0.4202924497911293 1.0 0.909350124651722 81 Q5H8A4,P03886,P51812,Q9HC21,Q86SQ9,Q9NZJ7,Q9NQZ5,Q14739,P04062,Q13510,P00846 11 +Decreased specific anti polysaccharide antibody level 0.7316430688179 0.8042483854800735 0.421253539907702 1.0 0.9094665260669084 3 Q05655,Q9H0U3 2 +Fibroadenoma of the breast 0.7316430688179001 0.8042483854800735 0.421253539907702 1.0 0.9094665260669084 3 P10644,Q05655 2 +Abnormal sacrum morphology 0.3432423290496743 0.8039160351269627 0.421445468663232 1.0 0.9094665260669084 30 Q5H8A4,P04066,Q15125,P53701,O96028,O95202,Q9Y4P3,P61978,O43909,Q14739,P49366,Q9UM00 12 +Premature skin wrinkling 0.3750436819093353 0.7994142677053526 0.4240502400661203 1.0 0.9115899887095616 19 Q9Y487,O75844 2 +Abnormal thyroid stimulating hormone level 0.7299967072769211 0.7981265178916045 0.4247970742586062 1.0 0.9115899887095616 3 P10644,P16870 2 +Abnormal nephron morphology 0.3071996840279659 0.7972296497723099 0.4253176692124256 1.0 0.9115899887095616 64 O75306,P03886,P06280,O95470,P23786,Q8NFH4,Q9Y4P3,Q14108,P16930,Q05655,O43826,P00846,Q9BW27,Q9NZ08,Q8N1F7 15 +Ovotestis 0.7198815009874795 0.7971724753902745 0.4253508692102956 1.0 0.9115899887095616 2 P53701 1 +Abnormality of the nasal tip 0.2876639728168026 0.7951726940070922 0.4265130532877477 1.0 0.9115899887095616 86 Q9UHX1,Q96A33,O43924,O75844,P23786,P16435,P42892,P21964,Q9Y487,Q7LGA3 10 +Abnormal circulating sex hormone concentration 0.371128103484617 0.7939231486845313 0.4272401725025139 1.0 0.9115899887095616 20 P49770,P16870,Q9NR50,Q969G3,P16435,Q15031,P57740,Q13423,Q8IY37 9 +Short palpebral fissure 0.352103068048676 0.7923205662494175 0.4281737827864833 1.0 0.9115899887095616 25 Q9NXE4,Q9UHX1,Q9BXW9,P55795,Q9Y619,Q6NUK1,Q15555,O75844 8 +Abnormality of thalamus morphology 0.3884558002185515 0.7920354226104296 0.4283400221516251 1.0 0.9115899887095616 16 O43819,Q13057,O75306,Q9GZY8,Q96RR1,Q969G3,Q96KP1,P11166 8 +Increased urine alpha ketoglutarate concentration 0.633399209486168 0.7907353806415842 0.4290984252381675 1.0 0.9115899887095616 4 P00367,P21281,P21912 3 +Contractures of the joints of the upper limbs 0.3011863365028951 0.7897047645907773 0.4297002081442596 1.0 0.9115899887095616 69 Q8IZA0,Q96L58,Q99720,P23786,Q9BUB7,P16435,P42892,Q9Y619,O43909,Q15392,Q9H4L7,O75844,P37268,Q7LGA3,P35637 15 +Recurrent hand flapping 0.7276560171482593 0.7894385961798469 0.4298557051007863 1.0 0.9115899887095616 3 P55795 1 +Fetal distress 0.3556023164090003 0.7869165018197092 0.4313307468209351 1.0 0.9115899887095616 24 P03886,Q96CU9,Q86Y39,O43676,Q86WC4 5 +Neurodegeneration 0.3444622014657043 0.7867559578976325 0.4314247398465158 1.0 0.9115899887095616 28 Q6DKK2,P17900,Q15165,P08236,P35637 5 +Recurrent fever 0.4020634138257247 0.7840736948162286 0.432996869518782 1.0 0.9115899887095616 13 P28070,Q13510 2 +Malabsorption 0.3154636106231206 0.7820486391288308 0.4341859893380562 1.0 0.9115899887095616 49 Q96A33,P06280,P40855,O76024,P09601,Q9Y4P3,Q14739,Q9NZ08,O75381 9 +Abnormality of cranial sutures 0.2837354826687119 0.7802000720865059 0.4352731199179533 1.0 0.9115899887095616 82 Q08AM6,P51812,P40855,O75844,P16435,Q9Y619,Q6NUK1,P07237,Q8NCH0,P21964,Q9Y487 11 +Impotence 0.528237708108083 0.7791276595478736 0.435904518199933 1.0 0.9115899887095616 5 Q969G3 1 +Erectile dysfunction 0.528237708108083 0.7791276595478736 0.435904518199933 1.0 0.9115899887095616 5 Q969G3 1 +Abnormality of the wrist 0.3435400333696006 0.7785061415881792 0.4362706874163846 1.0 0.9115899887095616 28 P16278,Q9H6K4,P16435,Q9BV10,Q13510,O75844 6 +Apraxia 0.3065135823318448 0.776912742335129 0.4372102529082136 1.0 0.9115899887095616 63 Q6DKK2,O43924,O60220,Q9Y619,P04062,Q10713,O14773,P05067,Q7LGA3 9 +Abnormal mitral valve physiology 0.3238060580562758 0.7764996401265116 0.4374540332135224 1.0 0.9115899887095616 38 P51812,P06280,Q96L58,Q5T2R2,P53701,Q9Y4P3,P04062,Q9NZ08,O75844 9 +Adrenal hyperplasia 0.7241579284491731 0.7764901588797428 0.437459629214918 1.0 0.9115899887095616 3 P16435 1 +Abnormal st segment 0.7233496666472745 0.7735044888642252 0.4392238731892721 1.0 0.9115899887095616 3 Q9HD47 1 +St segment elevation 0.7233496666472745 0.7735044888642252 0.4392238731892721 1.0 0.9115899887095616 3 Q9HD47 1 +Rieger anomaly 0.7219989293652593 0.7685202193184185 0.4421781830228972 1.0 0.9115899887095616 3 O95202 1 +Fractures of the long bones 0.7217648995719305 0.7676573168603684 0.4426908006058778 1.0 0.9115899887095616 3 Q13126,Q9BTW9 2 +Abnormal myocardium morphology 0.3325736757423651 0.7675309545524346 0.4427658961713721 1.0 0.9115899887095616 166 Q86Y39,O96000,P23786,Q9BUB7,Q14108,Q07021,P46976,P10253,P50402,P00846,Q00325,Q7KZN9,Q9BT22,P08236,Q9P0J0,Q08AM6,P06280,P16278,Q96RR1,Q53H12,P12235,P53701,O60783,P04062,P21912,Q96I36,Q9NVI7,Q99797,P15586,Q9H061,O75381,P03886,O76024,O60313,Q9Y4P3,O43676,P16930,Q9NZ08,P22626,O75306,Q9NPL8,P40855,Q96CU9,Q9Y5Y5,Q5XKP0,Q16836,Q13423,P42167,P54802 49 +Aplasia hypoplasia of the cerebellar vermis 0.3074495418400563 0.767019355380894 0.4430700077020972 1.0 0.9115899887095616 61 Q15907,O43505,O43924,Q9HC21,Q15125,P23786,Q969G3,Q8NFH4,O43175,Q6NUK1,Q10713,O60566,Q15042,Q15645,P15291,Q9Y487,Q9UM00 17 +Abnormal skin morphology of the palm 0.2856200149122825 0.7653281167780717 0.4440761853684336 1.0 0.9124221170916912 86 Q15907,Q9UHX1,O43909,Q06136,Q9NXE4,Q08AM6,Q6NUK1,P21912,Q8NCH0,P53634,Q96I36,O75381,O96028,O75431,P61978,P16615,O95721,Q9Y487,P51812,P40855,O95202,Q96S52,Q14739,Q9Y5Y5,Q9H4L7,P42167 26 +Clonic seizure 0.482474490864858 0.7631830313782179 0.4453542470787202 1.0 0.9138060005426086 7 Q9NZJ7 1 +Generalized clonic seizure 0.4940309775824824 0.7624557514770068 0.4457880426278504 1.0 0.9138060005426086 6 Q9NZJ7 1 +Vitritis 0.7201185380309436 0.761592642928494 0.4463031671486428 1.0 0.9141076575232672 3 P04439,P53701 2 +Adducted thumb 0.3517329727141289 0.7544566100743402 0.4505750901472514 1.0 0.9144224815156248 24 P42892,Q86XL3,Q9Y4P3,Q8NCH0 4 +Myalgia 0.323862940912022 0.7527048158151283 0.45162731538982 1.0 0.9144224815156248 37 P06280,O60313,P12235,P23786,Q14739,P21964,P51530,Q9NZ08 8 +Delayed eruption of permanent teeth 0.7174658406486596 0.7518422848058299 0.4521459097446902 1.0 0.9144224815156248 3 O43826 1 +Abnormality of the metaphysis 0.3124618765516573 0.7518013792172513 0.4521705124721111 1.0 0.9144224815156248 50 Q08AM6,Q9HC07,Q96HY6,P16278,Q9UG56,Q13126,P07237,Q86WC4,Q14739 9 +Abnormal b cell morphology 0.4391746624611143 0.7510225503987334 0.4526390845520724 1.0 0.9144224815156248 10 Q9BV10 1 +Rimmed vacuoles 0.3970956318734451 0.7507668705269948 0.4527929707529632 1.0 0.9144224815156248 13 P09651,Q9BTV4,O14979,P50402,P22626 5 +Abnormality of the intrinsic pathway 0.3970377578043338 0.7503793528566727 0.4530262625680523 1.0 0.9144224815156248 13 Q9Y487,Q9BV10 2 +Dyspnea 0.2936186822154692 0.7498432465731518 0.453349118952032 1.0 0.9144224815156248 99 Q9UHX1,Q96L58,P07602,Q9NZJ7,P23786,P46976,P10253,P00846,Q00325,Q92804,P51530,P35637,P06280,Q9UHD9,Q96RR1,P53701,P12235,P04062,Q13510,O75844,P03886,P51571,Q15165,P56192,P00387,Q9Y619,O75306 27 +Male pseudohermaphroditism 0.7168258149489545 0.74949379020382 0.4535596400588226 1.0 0.9144224815156248 3 P53701,Q9NX14 2 +Multiple prenatal fractures 0.4796584155179365 0.7488273978439453 0.4539612440343021 1.0 0.9144224815156248 7 Q14739 1 +Slow saccadic eye movements 0.4113220810971574 0.7482385347210792 0.454316291542993 1.0 0.9144224815156248 12 Q8IV08 1 +Tetralogy of fallot 0.3185273343144045 0.748004795499336 0.4544572650092882 1.0 0.9144224815156248 39 Q08AM6,Q9UHX1,P21964 3 +Congenital onset 0.3013252239884258 0.7475898038475061 0.45470761668881 1.0 0.9144224815156248 111 O43505,Q9UHX1,Q5H8A4,Q9HC21,P07602,Q9NZJ7,Q96N66,P12235,P55201,O60783,Q6NUK1,Q9BW92,Q9Y5U9,O43924,P51571,Q8NFH4,P46977,Q7LGA3,P08670,Q5XKP0 20 +Ectopic kidney 0.3920948982686472 0.7473351513900386 0.4548612791324316 1.0 0.9144224815156248 14 Q9UHX1,Q9Y4P3 2 +Stage 5 chronic kidney disease 0.3424735403059831 0.7460529757426847 0.4556354141063372 1.0 0.914940699635888 26 O95470,P23786,Q8NFH4,Q05655,O43826,Q9BW27,Q8N1F7 7 +Hepatomegaly 0.3333236629636303 0.7458455107714381 0.4557607442020053 1.0 0.914940699635888 171 Q9HC21,Q9UGP8,Q86SQ9,Q86Y39,Q15904,P09601,Q9NZJ7,P07602,P23786,O96000,P54802,Q6NUQ1,Q14108,Q9BUB7,Q07021,O43909,Q10713,P00846,P10253,O43826,O75880,Q9BT22,P61916,P28288,P08236,Q9P2J5,Q96A33,Q9H0U3,P16278,Q16134,Q96RL7,P04062,Q13510,Q96I36,Q9NVI7,P15586,O75381,P50416,P03886,P35610,P04066,P28070,O00754,P56192,Q01844,Q9Y619,O43676,Q86WC4,Q15067,P16930,P00374,Q9H9E3,Q9HC07,O75306,Q9NPL8,P40855,Q9UJS0,Q96CU9,Q96HY6,O60762,Q96S52,Q9UJW0,Q05655,Q14739,Q9Y5Y5,O15118 66 +Abnormal circulating carbohydrate concentration 0.3179957247709735 0.7425015703645934 0.457783500700422 1.0 0.9169780469776396 39 P03886,Q96CU9,Q86Y39,Q9BWD1,Q9NP80,O43676,Q5JRX3,Q70HW3 8 +Peripheral axonal neuropathy 0.3075538480651968 0.7412183912934313 0.4585610339656742 1.0 0.9177272958688308 58 Q13057,Q96BR5,Q9HC21,P07602,Q9NZJ7,P00846,Q9NRG9,Q9BTW9,Q8IV08,Q9BPX6,Q96RR1,P12235,Q96RL7,O15269,Q9NVI7,P03886,O76024,O60313,P56192,Q15067,O15270,P22626,Q6PI48,O95831 24 +Pedal edema 0.4894419221734241 0.7399704376115234 0.4593179323495175 1.0 0.9184339667067936 6 Q14108,P04062 2 +Decreased number of large peripheral myelinated nerve fibers 0.5191901919291475 0.7380700083885438 0.4604719078081927 1.0 0.9197769499515565 5 Q8TB36,O15269 2 +Abnormal conus terminalis morphology 0.4884635610500685 0.7351867147145548 0.4622257888926859 1.0 0.9218172352796266 6 Q5H8A4,O95202 2 +Bloodstream infectious agent 0.5178448908725998 0.7319921309703917 0.4641733707427209 1.0 0.9240808155398852 5 Q05655 1 +Abnormal heart sound 0.517414253004362 0.7300481405403224 0.4653607589815431 1.0 0.9247743306263416 5 P10253 1 +Blue sclerae 0.3595694760052076 0.7291841988120669 0.4658889954696987 1.0 0.9247743306263416 21 O75718,Q96L58,P00387,P07237,Q8NCH0 5 +Decreased circulating gonadotropin concentration 0.7097949509778992 0.7238010761762 0.4691878685601902 1.0 0.9262819984332292 3 Q969G3 1 +High narrow palate 0.3358176592447159 0.7220938864910709 0.4702367566264869 1.0 0.9262819984332292 29 Q9Y619,Q08AM6,P23786,P16435 4 +Anarthria 0.4855619276353908 0.7210209649442484 0.4708966159652941 1.0 0.9262819984332292 6 Q99720 1 +Serositis 0.3676382887713506 0.7209672875938061 0.4709296415817081 1.0 0.9262819984332292 18 Q12769,Q8NFH4,P57740,Q9BW27,O15460,Q9NZ08,Q8N1F7 7 +Type ii lissencephaly 0.6156126482213502 0.7195615615967564 0.4717949857924362 1.0 0.9262819984332292 4 O43505,P07942,Q9Y5P6 3 +Dilated cardiomyopathy 0.3181561053536622 0.7188743865049619 0.4722183193899523 1.0 0.926495710352654 38 O75306,P03886,P16278,Q96RR1,P53701,P23786,Q9BTV4,P12235,Q96RL7,P00846,Q16836,P42167 12 +Mandibular prognathia 0.3303724046756827 0.7164578194971457 0.4737087039085819 1.0 0.927457749127012 32 Q9NXE4,Q9UHX1,P51812,P16278,O00754,Q13045,Q6NUK1,P10644,Q9NVI7,P55011 10 +Abnormality of blood circulation 0.3024651514477369 0.7161363060176319 0.4739071876865981 1.0 0.927457749127012 62 Q9UHX1,Q9Y487,P23786,P04062,Q14739,P21964,Q9NZ08,O75844,P05067 9 +Bulbous nose 0.3178414364596075 0.7156687945063059 0.4741958837305962 1.0 0.927457749127012 38 Q96A33,Q13409,P23786,P16435,P42892,O43909,P21964,Q9BSJ2 8 +Optic atrophy 0.3365837319346222 0.7142272690356448 0.475086657463122 1.0 0.927457749127012 184 Q15907,Q5H8A4,O43505,Q9HC21,Q86SQ9,Q86Y39,O60220,P07602,Q9NZJ7,Q92620,Q9H2C2,P00846,Q7KZN9,Q9BSJ2,P50897,Q9BTW9,Q9P0J0,Q53FT3,P06280,P16278,Q9H6K4,Q9GZY8,Q96RR1,P51572,Q96PU5,Q9NVI7,O75381,Q9H061,Q6ZXV5,Q9Y5U9,P03886,Q5T2R2,O76024,Q3ZCQ8,O60313,Q15067,Q15555,P10644,Q86WC4,O00429,P21964,O75306,P51812,P40855,Q96CU9,Q9NR50,P49770,O95202,Q9Y5Y5,Q5XKP0 50 +Micromelia 0.3664799394686153 0.7122818428198985 0.4762902653593164 1.0 0.927457749127012 18 Q9UHX1,O75718,Q96HY6,Q14739,Q15392 5 +Small nail 0.3093585013213283 0.7065837808018891 0.4798251711139389 1.0 0.927457749127012 41 P51812,P23786,Q9Y4P3,Q14739,Q9BV10 5 +Abnormality of the optic nerve 0.352278022159555 0.7058806602189928 0.4802623555102672 1.0 0.927457749127012 237 Q15907,Q9UHX1,Q5H8A4,Q9HC21,O43505,Q86SQ9,Q86Y39,O60220,P07602,Q9NZJ7,O96000,Q92620,Q96L58,Q9H2C2,Q9UG56,Q10713,P00846,Q7KZN9,Q9BSJ2,P50897,Q9BTW9,Q9P0J0,Q53FT3,P06280,P16278,Q9H6K4,Q9GZY8,Q96RR1,P51572,Q969G3,P04439,Q96PU5,P04062,Q9NVI7,O75381,Q9H061,Q9Y5U9,Q6ZXV5,P03886,Q5T2R2,O76024,Q3ZCQ8,O60313,O00754,Q15067,Q15555,P10644,O43676,O95721,Q86WC4,O00429,P21964,Q9NZ08,P37268,Q7LGA3,O75306,P51812,P38435,Q9NPL8,P40855,Q96CU9,Q9NR50,P49770,O95202,O60762,Q13277,Q96S66,Q15042,Q9Y5Y5,Q5XKP0 70 +Eeg with spike wave complexes 0.3809845058339723 0.7031927118357632 0.4819356605637281 1.0 0.927457749127012 15 Q9NQZ5,O75503 2 +Abnormal retinal morphology 0.3416073073607218 0.7013869704862005 0.4830615510832594 1.0 0.927457749127012 200 Q9UHX1,Q5H8A4,Q86SQ9,P07602,Q9NZJ7,Q9UG56,Q9BV10,P00846,Q10713,Q7KZN9,P50897,O14773,Q9P0J0,P16278,P17900,P04062,Q13510,Q8NCH0,P51648,O75381,O75503,O43924,P03886,Q9Y4P3,Q9Y619,P10619,P21964,Q9NZ08,Q9Y487,Q7LGA3,P51812,P38435,P40855,Q96CU9,P06865,Q5XKP0,Q16836 37 +Smooth muscle antibody positivity 0.6951942067149453 0.7012248933076611 0.4831626769831632 1.0 0.927457749127012 2 P49327 1 +Lymphedema 0.4039211925577648 0.7010590934490276 0.483266137492687 1.0 0.927457749127012 12 Q14739,P08236 2 +Hypotension 0.3526300371649893 0.7009542721802128 0.4833315530533277 1.0 0.927457749127012 22 O43681,P07602,P35610,Q9NZJ7,P04062,Q06787,P49366,Q13423 8 +Beaking of vertebral bodies 0.4494322772865363 0.7005960773356426 0.4835551271345584 1.0 0.927457749127012 9 Q96L58,P16278,P04066,Q6NUQ1,P08236 5 +Cloverleaf skull 0.7031404380130462 0.699671479099328 0.4841324919213381 1.0 0.927457749127012 3 P16435 1 +Inflammatory abnormality of the eye 0.322450656926288 0.6953543183461898 0.4868332812649563 1.0 0.927457749127012 35 P28070,Q15800,Q14739,Q9NZ08,P51648 5 +Lung adenocarcinoma 0.6935483870967755 0.6949456580578535 0.4870893577349422 1.0 0.927457749127012 2 P30154 1 +Abnormal urine hormone level 0.6935483870967737 0.6949456580578464 0.4870893577349466 1.0 0.927457749127012 2 P10644 1 +Increased urinary cortisol level 0.6935483870967737 0.6949456580578464 0.4870893577349466 1.0 0.927457749127012 2 P10644 1 +Increased circulating cortisol level 0.6935483870967737 0.6949456580578464 0.4870893577349466 1.0 0.927457749127012 2 P10644 1 +Skin plaque 0.5091556774073507 0.692922367352485 0.48835827196764 1.0 0.9275356524700208 5 Q06136 1 +Aplasia hypoplasia of the phalanges of the hand 0.3067836476053189 0.6913264479661042 0.4893604147423029 1.0 0.9279285229940544 51 Q08AM6,Q9UHX1,P51812,Q9BXW9,P38435,Q03164,Q969G3,P16435,Q96S52,Q6NUK1,P10644,O43909,P42345,Q14739,Q5JRA6,O75844,Q9H9E3 17 +Proximal muscle weakness 0.302544589035667 0.6894269503360938 0.4905546284949436 1.0 0.9280563469532216 59 P21912,Q99720,O60313,Q96RR1,P12235,Q9NP80,Q13126,P10253,P50402,P00846,P51530,Q13510,P22626,P35637 14 +Abnormal cranial nerve physiology 0.2966667987685455 0.6893997372010354 0.4905717487630558 1.0 0.9280563469532216 66 Q9UHX1,P51812,P40855,P07602,Q9NZJ7,P12235,Q86WC4,Q13510,Q9NZ08 9 +Incomplete penetrance 0.3318759568235072 0.6865585104585445 0.4923609812385865 1.0 0.9280563469532216 29 O95140,P03886,P36551,Q9UBB4,O60313,Q06787,Q969G3,Q92733,O14979,Q14671,P00846,P21912 12 +Cardiorespiratory arrest 0.6912442396313114 0.6861815650989832 0.4925986212501001 1.0 0.9280563469532216 2 Q96L58 1 +Drowsiness 0.4669844043503552 0.6845722987433798 0.4936138522940789 1.0 0.9280563469532216 7 Q5H8A4,O00754 2 +Centrally nucleated skeletal muscle fibers 0.4780317965373217 0.6844227201369156 0.4937082731780358 1.0 0.9280563469532216 6 Q9BPX6,P22626 2 +Diffuse white matter abnormalities 0.427725456034324 0.6841136209975698 0.4939034213732447 1.0 0.9280563469532216 10 O43819,O75306,Q9H936,P16278,Q3ZCQ8 5 +Abnormal response to endocrine stimulation test 0.6987767651268872 0.6839535765052194 0.4940044808799297 1.0 0.9280563469532216 3 P16435 1 +Neck flexor weakness 0.6062275252061093 0.6825086018106014 0.494917405512878 1.0 0.929170151744978 4 Q99720,P35637 2 +Abnormal circulating androgen level 0.4005993757866071 0.6799587488697357 0.4965305809040283 1.0 0.9296677467548728 12 P16870,Q969G3,P16435,Q13423,Q8IY37 5 +Polycystic kidney dysplasia 0.3864662405357447 0.6798285621325405 0.4966130192601321 1.0 0.9296677467548728 13 P21964 1 +Cataplexy 0.605087788096458 0.6780352195183328 0.4977493626786322 1.0 0.929680795167114 4 P61916,O15118 2 +Hepatic encephalopathy 0.6969261331050384 0.677313753294245 0.4982069065823498 1.0 0.929680795167114 3 Q9UJS0 1 +Premature loss of teeth 0.3816555827864401 0.6761672297448665 0.4989344759997192 1.0 0.929680795167114 14 Q08AM6,Q5JRA6,O75844,P04080 4 +Hypolipoproteinemia 0.4620942833535608 0.6738535072307613 0.5004044529676799 1.0 0.929680795167114 8 Q10471,Q15800,P37268,Q9UJS0 4 +Hepatitis 0.3718960782345797 0.6736692440503226 0.5005216195280158 1.0 0.929680795167114 16 Q9Y619,Q05655 2 +Aplasia hypoplasia involving bones of the lower limbs 0.2773139217891683 0.6732896187014945 0.5007630559593301 1.0 0.929680795167114 80 Q9UHX1,Q5H8A4,Q96L58,Q9BV10,Q5JRA6,Q08AM6,Q96A33,Q13510,P13073,O96028,O75431,Q9NX62,Q9Y619,P10644,Q10471,Q9H9E3,Q7LGA3,Q03164,Q96HY6,O00116,O95202,Q96S52,P50542,Q06787,P55011 25 +Nasal regurgitation 0.68729427254773 0.6712319637500463 0.5020727692173397 1.0 0.9299842315400714 2 P53007 1 +Sporadic 0.3553049095414727 0.6710246583320809 0.5022048211396921 1.0 0.9299842315400714 20 P51812,Q9BWD1,O96028,P04350,O95202,P04062,P21912 7 +Increased circulating gonadotropin level 0.4250210956839895 0.6683842559740839 0.5038883427078982 1.0 0.9311163604740263 10 P16435,Q15031,P57740,Q06787,Q8IY37 5 +Disproportionate short trunk short stature 0.6023582713192062 0.6673464657292274 0.5045508526200209 1.0 0.9311163604740263 4 Q9UHX1 1 +Subsarcolemmal accumulations of abnormally shaped mitochondria 0.6020343847967897 0.6660804502557308 0.505359679593949 1.0 0.932027497561804 4 P12235 1 +Depression 0.2849959159077005 0.6638474747400519 0.5067879368568515 1.0 0.933729576655252 95 O43464,Q6DKK2,Q13057,P07602,Q9NZJ7,Q96N66,P51530,Q92804,P50897,P35637,Q9NZ01,P06280,Q9UHD9,Q96RR1,P12235,Q96RL7,P04062,P53680,O43681,P03886,O76024,O00754,Q15165,Q9Y4P3,P10644,O15460,P21964,P51812,Q06787,Q9UBB4,P55011 31 +Thoracolumbar kyphosis 0.4625494521599568 0.6622446194742252 0.5078144627040215 1.0 0.9343645610446664 7 P04062,O43909,P08236 3 +Stuttering 0.6924596641422294 0.6613548880962924 0.5083847491471372 1.0 0.9343645610446664 3 Q9Y4W2,P03886 2 +Capillary malformation 0.374255148381764 0.6564316482909468 0.5115464328948638 1.0 0.9351353201075564 15 Q9UHX1 1 +Aplasia hypoplasia affecting the fundus 0.3435068904329786 0.6554328868280409 0.5121890833932856 1.0 0.9351353201075564 23 Q9UHX1,P07196,P61978,Q96KP1,O95721,O14936,Q9NVI7,P37268,Q9H3S7 9 +Hypokinesia 0.422550671168162 0.6540443816398275 0.5130832126124503 1.0 0.9351353201075564 10 P12235 1 +Eyelid myoclonus 0.4224242401312754 0.6533112715866776 0.5135556272717428 1.0 0.9351353201075564 10 P00374,Q13510 2 +Abnormal electrophysiology of sinoatrial node origin 0.3780845704395571 0.6519495637424113 0.5144337095767675 1.0 0.9351353201075564 14 Q9HD47 1 +Calvarial hyperostosis 0.5980962749222505 0.6507274745573248 0.5152224243869672 1.0 0.9351353201075564 4 P10644,P22626 2 +Agitation 0.321596711497654 0.6505005085360911 0.5153689733634721 1.0 0.9351353201075564 33 Q9UHD9,P35610,Q15165,O96008,P42892,P10644,P04062,Q92804,P05067,P35637 10 +Skin pit 0.4088929310959494 0.6483751054779165 0.5167423676605165 1.0 0.9351353201075564 11 P16615,O96028,O95202 3 +Abnormality of the helix 0.3228730201526649 0.6463419411224889 0.5180579315586966 1.0 0.9351353201075564 32 O75844,Q7LGA3,P21964 3 +Abnormality of the thoracic cavity 0.4210958408869404 0.6456132547543872 0.518529851107354 1.0 0.9351353201075564 10 Q01844,Q969G3,Q9H0U3,Q05655 4 +Fetal akinesia sequence 0.4979787131828284 0.6431963185617177 0.5200967218024428 1.0 0.9351353201075564 5 P04062 1 +Abnormal motor evoked potentials 0.6797235023041488 0.6428525805981584 0.5203197611174399 1.0 0.9351353201075564 2 P07196 1 +Spinal muscular atrophy 0.4077898095804491 0.6417117408956955 0.5210603645326239 1.0 0.9351353201075564 11 Q13510 1 +Gastroesophageal reflux 0.2971138212931113 0.640529274240697 0.5218285635076569 1.0 0.9351353201075564 116 Q9UHX1,Q8IZA0,Q86SQ9,P07602,Q9NZJ7,P55795,Q9BV10,P00846,Q96A33,P12235,P16435,Q6NUK1,Q6ZXV5,Q9Y584,P51571,Q9Y4P3,Q9Y619,P21964,Q01105,Q14739 20 +Abnormal cartilage morphology 0.3938727951915938 0.6374014451544369 0.5238633872904996 1.0 0.9351353201075564 12 Q9UHX1 1 +Postaxial hand polydactyly 0.4378184523121535 0.6372382593001633 0.5239696601689485 1.0 0.9351353201075564 9 O43924,Q14739 2 +Tetraparesis 0.3164647080181949 0.6371268599648287 0.5240422140302761 1.0 0.9351353201075564 35 P07602,P17900,Q9NZJ7,P00846,Q9UBX3 5 +Heterotaxy 0.4965579667388983 0.6369226694762383 0.5241752157018866 1.0 0.9351353201075564 5 Q5H8A4,O95202 2 +Hyperactive patellar reflex 0.4548342304532727 0.6366199979713039 0.5243723958670219 1.0 0.9351353201075564 8 P13073,P21912 2 +Coarse facial features 0.2986061968379959 0.6346781633261788 0.5256383383573526 1.0 0.9351353201075564 58 Q96A33,P51812,P06280,P16278,P54802,P04066,O00754,Q969G3,P15586,P61978,Q9Y4P3,Q96S52,O43909,P10619,Q06787,P38159,P08236,Q7LGA3 18 +Abnormal lymphocyte morphology 0.3198837686463798 0.6343193128651126 0.5258724551438725 1.0 0.9351353201075564 33 Q9H0U3,P16278,O95470,P04066,P28070,Q05655,O43909,Q9BV10 8 +Complex febrile seizure 0.6774193548387026 0.6342897172897769 0.5258917659029678 1.0 0.9351353201075564 2 Q9H9E3 1 +Abnormal odontoid tissue morphology 0.3097965454902251 0.6339062940828261 0.5261419777285441 1.0 0.9351353201075564 38 Q9HC07,Q96L58,P16278,Q9Y4P3,P07237,P21964,P51648 7 +Nasal speech 0.3214821073961973 0.6333800468511329 0.5264854917503592 1.0 0.9351353201075564 32 Q9Y487,P21964 2 +Abnormality of the pubic bone 0.4956742589594771 0.6330261575128463 0.5267165615483014 1.0 0.9351353201075564 5 Q5H8A4,Q8IZA0,O95202 3 +Postaxial polydactyly 0.3660812084610929 0.6324412836600701 0.5270985646949695 1.0 0.9351353201075564 16 O43924,Q15125,O43909,Q14739,Q10713,Q9UM00 6 +Otitis media 0.3018130906328192 0.6319264400356578 0.5274349454223828 1.0 0.9351353201075564 50 Q96A33,Q5H8A4,Q8N5M9,Q9Y4P3,Q05655,Q14739,P21964 7 +Meningocele 0.4537320223503686 0.6309885915478378 0.5280479839208339 1.0 0.9351353201075564 8 P21964 1 +Ambiguous genitalia 0.3527419574827874 0.6294760321679488 0.529037455116868 1.0 0.9351353201075564 19 P53701,O43175,P16435,Q9NX14,O60566,Q15392,Q15645 7 +Abnormal corpus striatum morphology 0.3552516602722689 0.6284906636803791 0.5296825608735423 1.0 0.9351353201075564 18 O75306,Q13057,O60220,Q96RL7,P00846,O95831 6 +Abnormal greater sciatic notch morphology 0.4942547492612404 0.6267764741831888 0.530805766762444 1.0 0.9351353201075564 5 Q96HY6,P08236 2 +Chromosomal breakage induced by crosslinking agents 0.6826615539022711 0.6266901878365471 0.5308623369820036 1.0 0.9351353201075564 3 P13073 1 +Hypohidrosis 0.45236171279017 0.6239957389060652 0.5326303834686037 1.0 0.9351353201075564 8 Q9H4L7,P06280,P04080 3 +Demyelinating peripheral neuropathy 0.3597492809630931 0.6228075561338359 0.533410992278776 1.0 0.9357834955172202 17 P00846 1 +Abnormal head movements 0.391202065445031 0.6205753469529737 0.5348790645332859 1.0 0.936349825078828 12 Q99720,Q96RL7,P35637,Q06787 4 +Recurrent sinusitis 0.4918704786031845 0.6163056541374597 0.5376928078455099 1.0 0.939310515702467 5 Q05655 1 +Vertebral compression fracture 0.3682067405358471 0.6146361622304072 0.5387950271410107 1.0 0.9400072246332484 15 Q14108,P07237,P04062,Q96HY6 4 +Elbow flexion contracture 0.3310913970315709 0.6134060744338136 0.5396078705371865 1.0 0.9400072246332484 25 Q96L58,P23786,P16435,O43909,O94905,P50402,P37268,Q7LGA3 8 +Convex nasal ridge 0.3505067960283529 0.6126099165509374 0.5401342996800695 1.0 0.9400072246332484 19 O95202,Q6NUK1,P51530,O75844,Q9H9E3 5 +Elevated serum acid phosphatase 0.5882210751199486 0.6125740343408822 0.540158031477536 1.0 0.9400072246332484 4 Q9NZJ7 1 +Abnormality of chromosome segregation 0.5877303391642995 0.610691602435475 0.5414037664689659 1.0 0.941095045344794 4 Q14739,O60566 2 +Vasculitis 0.4325541370742822 0.6087304399451601 0.5427031269252605 1.0 0.9419139734387676 9 Q9NZ08 1 +Ectodermal dysplasia 0.6698485845951083 0.6064109394757536 0.5442419059825285 1.0 0.9419979864061796 2 Q9H4L7 1 +Abnormal placental membrane morphology 0.6698485845951083 0.6064109394757536 0.5442419059825285 1.0 0.9419979864061796 2 Q9H4L7 1 +Decreased proportion of cd8 positive t cells 0.6691902567478429 0.6040058106440173 0.5458397789930096 1.0 0.9425596683055364 2 O43909 1 +Abnormal endocrine physiology 0.4889203680200711 0.603397113768287 0.5462445418319017 1.0 0.9425596683055364 5 P16435 1 +Spinal cord compression 0.4884390217235399 0.6012960138007123 0.5476428441073784 1.0 0.9425596683055364 5 P51530,Q96L58 2 +Breech presentation 0.447842579865075 0.601002507169591 0.5478383164033196 1.0 0.9425596683055364 8 Q9Y619,O60313 2 +Cns hypomyelination 0.3107564602580921 0.6008065054749266 0.5479688706519776 1.0 0.9425596683055364 36 Q9NXE4,P49770,Q9NR50,Q99720,P00387,O00400,Q9BTW9,P35637 8 +Rectal prolapse 0.4309946220824106 0.6003139114964641 0.5482970491364978 1.0 0.9425596683055364 9 Q9Y4P3 1 +Oculomotor apraxia 0.3254087086713325 0.5980736564573553 0.5497907870332503 1.0 0.9427057256744272 26 O43924,O00429,P04062,Q10713,O14773,P05067 6 +Coloboma 0.2989442344535571 0.5944608421936607 0.5522039251500241 1.0 0.9441373091904376 42 O43505,Q9UHX1,Q5H8A4,P78318,Q96EK5,O43924,P53701,Q92620,O96028,O95202,P61978,Q9NP72,Q9NX14,Q10713,O14936,Q15042,Q9NRG9 17 +Heinz bodies 0.66655694535879 0.5944167711995081 0.5522333939400164 1.0 0.9441373091904376 2 O14936 1 +Dermal translucency 0.4294763984505539 0.5921335492696548 0.5537611627413845 1.0 0.9441752358735226 9 Q6NUK1,O75844 2 +Myositis 0.4292002233668844 0.5906469304640743 0.554757013038158 1.0 0.9451646637867344 9 Q9NZ08,P28070 2 +Cerebral white matter atrophy 0.3387351805181722 0.5899600944769415 0.5552174035379966 1.0 0.9455948965534808 22 O60313,O00754,P51572,O43175,O00429,Q9Y5Y5,Q9H9P8,O75503 8 +Aplasia hypoplasia involving bones of the feet 0.2945376680599362 0.5863806478512179 0.5576197460790095 1.0 0.946497098848289 58 Q08AM6,Q96A33,Q9UHX1,Q5H8A4,Q13510,Q7LGA3 6 +Abnormal circulating estrogen level 0.4104709930009312 0.5843827198792919 0.5589628500205861 1.0 0.9469714326160128 10 Q969G3,P16435,Q15031,P57740,Q8IY37 5 +Athetosis 0.359156692391409 0.5836543285081034 0.5594529004563888 1.0 0.9469714326160128 16 Q96CU9,O14949,Q9UHD9,O00584,P00387 5 +Biparietal narrowing 0.4442488020629321 0.5827969047471688 0.5600300288919817 1.0 0.9469714326160128 8 O43924 1 +Psoriasiform dermatitis 0.6698416564865061 0.5821074284461296 0.5604943218353584 1.0 0.9471354643495712 3 Q15800 1 +Absent septum pellucidum 0.3172033574312259 0.5795429095601304 0.5622229021072678 1.0 0.9481504200553856 31 Q9NZ01,O43505,Q13409,P51571,P53701,Q96N66,O96028,O95202,O43175,Q15392,P55011 11 +Generalized muscle weakness 0.315251690926414 0.575524388960188 0.5649367010193562 1.0 0.949229250230678 32 Q9UHD9,Q15165,P12235,P10253,Q92804,P35637 6 +Generalized dystonia 0.5770504535155558 0.5700659476956824 0.5686329699993433 1.0 0.9525926836676856 4 O60220 1 +Aspiration 0.4248825296578321 0.5674654025146066 0.570398025911595 1.0 0.9525926836676856 9 P17900 1 +Penetrating foot ulcers 0.6655647424119109 0.5674438854228029 0.5704126409912358 1.0 0.9525926836676856 3 O15269 1 +Trophic changes related to pain 0.6655647424119109 0.5674438854228029 0.5704126409912358 1.0 0.9525926836676856 3 O15269 1 +Emg slow motor conduction 0.6655647424119109 0.5674438854228029 0.5704126409912358 1.0 0.9525926836676856 3 O15269 1 +Impaired distal tactile sensation 0.6655647424119109 0.5674438854228029 0.5704126409912358 1.0 0.9525926836676856 3 O15269 1 +Antiphospholipid antibody positivity 0.665185792982734 0.5661499530656655 0.5712918480446825 1.0 0.9529910585827872 3 Q05655 1 +Abnormal sclera morphology 0.3216077233096315 0.5654367087013555 0.5717767621025427 1.0 0.9531998245519628 26 O75718,Q96L58,P00387,P10644,P07237,Q8NCH0,Q9H9E3 7 +Pneumonia 0.2949296271931752 0.5641995642363038 0.5726183243580483 1.0 0.9531998245519628 53 P16278,O60220,O00754,Q969G3,Q6NUK1,Q86WC4,O43909,Q9BV10,Q13510,P04062,Q05655,Q9BTW9 12 +Thyroiditis 0.4401989901906346 0.5623717262353802 0.5738627785595396 1.0 0.9531998245519628 8 P42224,P49327,Q05655,O43826,P00813,Q96J02 6 +Congenital hip dislocation 0.3285335651607493 0.5616691043417501 0.5743414881161644 1.0 0.9531998245519628 24 Q9UHX1 1 +Upper limb asymmetry 0.6573403554970214 0.561264915524792 0.5746169552096454 1.0 0.9531998245519628 2 Q15555 1 +Psychosis 0.324769914508078 0.5602180769412222 0.5753306983368704 1.0 0.9531998245519628 25 Q6DKK2,P03886,P51812,O76024,Q9UJS0,Q96RR1,P10644,Q5JRX3,P61916,O15118 10 +Abnormal meningeal morphology 0.3434926452558923 0.5599561931649125 0.575509318337796 1.0 0.9531998245519628 19 Q9UHX1,P21964 2 +Abnormal circulating free fatty acid concentration 0.5741961869860012 0.5593244210628701 0.5759403315439409 1.0 0.9531998245519628 4 Q16836,P40939 2 +Nephropathy 0.3432268313926135 0.5579697349125405 0.576865050998363 1.0 0.9531998245519628 19 Q14108,P03886,P06280,Q10713 4 +Anti thyroid peroxidase antibody positivity 0.6560236998025031 0.5565827507873239 0.5778125417361726 1.0 0.9536509148479728 2 Q96J02 1 +Decreased circulating igg subclass level 0.6560236998025031 0.5565827507873239 0.5778125417361726 1.0 0.9536509148479728 2 P17812 1 +Abnormal cornea morphology 0.3063430745068798 0.5563426968573276 0.5779766041406598 1.0 0.9536509148479728 142 O43505,Q5H8A4,Q96L58,Q86SQ9,Q92620,Q07021,O60566,Q06136,Q15645,P08236,Q08AM6,P06280,P16278,Q53H12,P53701,P12235,Q6NUK1,P04062,Q13510,Q8NCH0,P51648,O75844,Q9NVI7,Q9NWM8,O75381,P04066,O00754,Q9Y4P3,Q15555,P10619,P21964,Q9NZ08,Q7LGA3,P40855,O95202,Q14739,Q9Y5Y5 37 +Ichthyosis 0.3128347867152959 0.5531848299826967 0.5801368535949138 1.0 0.9547910806813544 32 P40855,O95470,Q15125,Q15800,Q9BTV4,O43175,P04062,O95721,P50402,Q9Y5Y5,P51648,O75381 12 +Proximal upper limb amyotrophy 0.440394502478227 0.552262681473747 0.5807683947631621 1.0 0.954979453210537 7 O14979,P50402 2 +Abnormality of the musculature of the upper arm 0.440394502478227 0.552262681473747 0.5807683947631621 1.0 0.954979453210537 7 O14979,P50402 2 +Abnormal atrioventricular valve physiology 0.2951106518291328 0.5520981562378247 0.5808811050854157 1.0 0.954979453210537 47 O43819,O75306,P51812,P06280,Q96L58,Q5T2R2,Q15904,P36543,P53701,O00754,O75431,Q9Y4P3,Q6NUK1,P10644,P04062,P40939,Q9NZ08,O75844 18 +Fibrous tissue neoplasm 0.3545643921813715 0.5515162446086502 0.5812798339468508 1.0 0.9552897271041272 16 Q969G3,Q13126,Q05655,Q15392,P21912 5 +Cranial hyperostosis 0.392619530227066 0.5508206986853355 0.581756593522549 1.0 0.9557279681957658 11 P51812,O00754,Q96L58,P22626 4 +Abnormality of corneal size 0.3009277642069433 0.544373800672559 0.586184270879127 1.0 0.9578161376818805 38 O43505,Q5H8A4,Q96L58,Q15125,O96028,O95202,Q9Y4P3,Q15555,Q8NCH0,Q15042,Q9NWM8 11 +Hypertriglyceridemia 0.3329291702275588 0.5440652704976703 0.5863965582422592 1.0 0.9578161376818805 22 Q9UJS0,O95470,P28070,Q9BTV4,O75431,Q13045,O43826,P50402 8 +Hemoglobinuria 0.6585446163977622 0.5436179925543786 0.586704375713003 1.0 0.9579749479965723 3 P11413,O14936 2 +Death in infancy 0.2908087738785668 0.5422396282823793 0.5876534390241357 1.0 0.9582842374704774 58 Q9HC21,O75718,P16278,P40855,P07602,Q9NZJ7,Q9BUB7,Q15067,Q13277,Q6NUK1,P04062,O00429,Q9Y5Y5,Q9BT22,O75381 15 +Positive romberg sign 0.4193923461475628 0.5381627496060771 0.5904646944657772 1.0 0.9596369757502038 9 Q8IV08 1 +Macular purpura 0.3777151136732016 0.5363507806485001 0.591716141125741 1.0 0.96132740213607 12 P04062,Q8NCH0 2 +Abnormality of the supraorbital ridges 0.3286379797995158 0.5351418639614948 0.5925517632284047 1.0 0.9619978482962216 23 Q6NUK1,P51812,P40855,P16435 4 +Sound sensitivity 0.418259123400496 0.5321403291109958 0.594628807258551 1.0 0.9646813281808664 9 P17900,Q9Y4P3 2 +Glomerular sclerosis 0.3103974329890456 0.5307238659469348 0.595610145177742 1.0 0.9659288949780922 32 P03886,O95470,Q12769,Q02978,Q8NFH4,O75431,Q14108,P16930,O43826,Q9BW27,P21912,Q8N1F7 12 +Impaired distal proprioception 0.6542994224293059 0.5293625157002129 0.596553995894332 1.0 0.9666481504359844 3 Q96RR1 1 +Abnormal acetabulum morphology 0.3391138127290315 0.527325114640022 0.5979678366405603 1.0 0.9666481504359844 19 O75718,Q96L58,P16278,Q9Y584,O43909,P08236 6 +Moderately reduced visual acuity 0.6527122136206063 0.5240631133134458 0.6002346433080124 1.0 0.967587803373883 3 O60313 1 +Abnormal blood gas level 0.6523097463675647 0.5227220267718885 0.6011677076099766 1.0 0.9684044786617888 3 A5YKK6 1 +Movement abnormality of the tongue 0.563971927328932 0.5212804632797232 0.6021714086594923 1.0 0.9689849405624328 4 P10253,P04350 2 +Calcific stippling 0.65101315407963 0.5184089990376232 0.604172937308147 1.0 0.9696614911828452 3 Q15125 1 +Widely spaced teeth 0.3160239350490045 0.5177826960313593 0.6046098927697356 1.0 0.9696614911828452 26 Q96A33,P51812,P16278,P51571,O00754,Q9BTW9,P08236 7 +Abnormal urine protein level 0.2891898860036696 0.5171140907304261 0.6050765178532322 1.0 0.9696614911828452 57 Q9Y5U9,P03886,P06280,O95470,P09601,Q8NFH4,Q9Y4P3,Q14108,Q8N1F7,P04062,O43826,Q9BW27,P21912,O95721,Q5JRA6 15 +Lymphopenia 0.3193151220004953 0.5146689364803659 0.6067843838678773 1.0 0.9705563158280496 25 Q9H0U3,O95470,P28070,Q05655,Q9BV10 5 +Abnormal cerebellar vermis morphology 0.2778941266304545 0.5141566221082184 0.607142492660512 1.0 0.9707877677021683 71 Q15907,O43505,Q9HC21,P23786,Q10713,O60566,Q15645,Q969G3,Q6NUK1,P15291,Q9UM00,O43924,Q15125,Q8NFH4,Q9Y487,O43175,Q96S52,Q14671,Q9Y5Y5,Q15042 20 +Decreased cd4 cd8 ratio 0.6491808973725439 0.5123336215640045 0.6084175384127035 1.0 0.9715906026443628 3 Q9H0U3 1 +Spina bifida 0.3083834811814951 0.5122203036181833 0.6084968347826449 1.0 0.9715906026443628 32 Q9UHX1,Q9HC21,Q9Y4P3,P21964 4 +Furrowed tongue 0.4676827450674458 0.5121983972500588 0.6085121647078595 1.0 0.9715906026443628 5 Q15042,P21912 2 +Brain imaging abnormality 0.3097686076608109 0.511912124661519 0.6087125120985786 1.0 0.9715906026443628 31 O75306,P03886,P07602,Q9NZJ7,Q969G3,O00429,Q9BV10,P21912,Q9BT22 9 +Tall stature 0.2913470554218146 0.5109980636819015 0.6093524126344061 1.0 0.9722708260518812 47 Q5H8A4,Q3ZCQ8,P36543,O00754,O96028,P04350,O95202,P16435,P61978,Q15031,P10644,Q8NCH0,P51530,Q13423,A5YKK6,Q9NWM8,P55011,Q7LGA3 18 +Joint contracture of the hand 0.2911528804289766 0.508557694722843 0.6110622888190285 1.0 0.9728832400268588 46 Q8IZA0,P16435,Q9Y619,Q15392,O75844 5 +Spastic tetraparesis 0.3218753641391477 0.5072307006150689 0.6119929561871809 1.0 0.973067340688066 24 P17900,Q9NZJ7,P00846 3 +Oral ulcer 0.4310714096667621 0.5069290513768191 0.6122046008022082 1.0 0.973067340688066 7 Q9NZ08 1 +Zonular cataract 0.3849424023675272 0.5054566570369814 0.6132381336220862 1.0 0.9736672028234246 11 P08670,O76024,Q9H6K4 3 +Abnormal vitreous humor morphology 0.4401462869337921 0.5050423710862074 0.6135290763812891 1.0 0.9736672028234246 6 P04439,P53701 2 +Type 1 muscle fiber atrophy 0.4306441008428454 0.5048670721830038 0.6136522027906701 1.0 0.9736672028234246 7 Q9BTV4,P50402 2 +Heterotropia 0.2906901459396865 0.5043527674258226 0.6140135029416791 1.0 0.9738802184398528 44 O43819,Q9UHX1,O43924,P55795,Q10471,O43175,O60762,P00387,P04062,P40939,P50542,Q9Y3E5,Q9NVI7 13 +Abnormality of upper limb epiphysis morphology 0.3596658629753208 0.5040665258193919 0.614214628864352 1.0 0.9738802184398528 13 P51812,O95202,P16435,P10644,Q5JRA6,Q9H9E3 6 +Abnormality of primary teeth 0.3473763619562544 0.5016205699488531 0.6159344471543666 1.0 0.9751816594300678 16 Q08AM6,P04080,P61978,Q13045,P53634,O75844,Q9UM00 7 +Poor motor coordination 0.3554679001869631 0.5007151397236979 0.6165716157106167 1.0 0.9752379276312918 14 O95140,Q6PI48,Q96RL7,Q10713,Q06787,O75503 6 +Abnormal lower limb bone morphology 0.307710655727984 0.500309362613304 0.6168572626027422 1.0 0.9753506039554656 152 O43505,Q9UHX1,Q5H8A4,O75718,Q96L58,P07602,Q9NZJ7,Q6NUQ1,O43909,Q9BV10,Q15392,Q10713,Q5JRA6,P08236,Q9NXE4,Q08AM6,Q96A33,Q9BXW9,P06280,P16278,P16435,P04062,P40939,Q13510,P13073,O75844,O43924,Q9H936,P04066,Q15125,O00754,O96028,O75431,Q9NX62,Q9Y619,P10644,P21964,Q10471,Q9Y487,Q9H9E3,Q7LGA3,P51812,Q03164,Q96HY6,O00116,O95202,O43175,Q96S52,Q14739,P50542,Q06787,P55011 52 +Thickened skin 0.2736992834777507 0.4993710422948919 0.6175180154663811 1.0 0.9756057220068411 95 P98194,P31751,Q9BTV4,P14324,P50402,Q06136,P06280,P16278,O95470,O15269,P04062,P21912,P53634,P51648,O75844,Q9NWM8,O75381,P04066,P28070,Q15125,O75431,P16615,Q15555,O95721,O15270,P40855,Q15800,O43175,Q14739,P50542,Q9Y5Y5,Q9H4L7,P42167 33 +Abnormal upper limb bone morphology 0.2708521632204878 0.4982643580150793 0.6182977260066873 1.0 0.976270862757522 91 Q08AM6,Q9UHX1,O43924,P51812,P16278,Q9Y4P3,P16435,Q14739,Q9BV10,O75844,P08236,Q7LGA3 12 +Increased vertebral height 0.6447151794533992 0.4976237081823956 0.6187492901948537 1.0 0.9766440716329972 3 O00754,Q96J02 2 +Dilatation of the ventricular cavity 0.6385780118499027 0.495904901297158 0.6199615079605267 1.0 0.9773647615393172 2 Q9Y5P6 1 +Joint dislocation 0.2661820761746804 0.4921810860403769 0.6225913340548483 1.0 0.9773647615393172 85 Q6ZXV5,Q08AM6,Q9UHX1,Q96A33,Q96L58,P51571,Q9Y487,Q9NX62,O95202,Q9Y4P3,Q9Y619,O43909,Q96PU5,P21964,Q8NCH0,O75844,Q9BTW9 17 +Fasting hyperinsulinemia 0.5560109030415485 0.4921586362177197 0.6226072031858532 1.0 0.9773647615393172 4 Q16836,P40939 2 +Opisthotonus 0.3231054720529449 0.4909774909431823 0.6234423677941505 1.0 0.9773647615393172 23 P07602,Q99720,Q9NZJ7,P00387,P04062,P35637 6 +Hyperacusis 0.4255548307999635 0.4894237814139959 0.6245417029083347 1.0 0.9773647615393172 8 P17900 1 +Impaired distal vibration sensation 0.4618802548941235 0.4878772465283886 0.6256367920630233 1.0 0.9773647615393172 5 Q96RR1 1 +Congenital malformation of the great arteries 0.2749240834847897 0.4874739067352193 0.6259225297678679 1.0 0.9773647615393172 98 Q6ZXV5,Q08AM6,Q9UHX1,P40855,P0DP25,Q9Y4P3,P42892,Q6NUK1,Q9BV10,Q15392,P21964,O75844,Q9NWM8 13 +Peptic ulcer 0.3818106644938467 0.4870967196043213 0.6261897910026104 1.0 0.9773647615393172 11 P04062,Q9Y4P3 2 +Vertebral hypoplasia 0.3933091886553232 0.4870603900561182 0.6262155354070007 1.0 0.9773647615393172 10 P10644,Q14739,Q96HY6,P16278 4 +Transient ischemic attack 0.4245746666148612 0.4845977301973742 0.627961724104392 1.0 0.9773647615393172 8 O75844 1 +Restrictive ventilatory defect 0.3812699576080041 0.4839359785551726 0.6284313055529562 1.0 0.9773647615393172 11 Q05655,P16278 2 +Sleep apnea 0.3306048486906947 0.4827524099160161 0.6292715452641513 1.0 0.9779830062885632 20 Q96A33,P51812 2 +Scleral staphyloma 0.6394468225222198 0.4804526572026744 0.6309055592883628 1.0 0.9790936686296527 3 P40939,Q969N2 2 +Abnormal waist to hip ratio 0.4252668112734711 0.4790464238143201 0.6319056028366008 1.0 0.9790936686296527 7 P18031,O76024,P43304 3 +Retinal atrophy 0.3112689979299083 0.4775190431802574 0.6329925637509985 1.0 0.9793953163101812 26 P51648,P04062,Q7LGA3 3 +Ankyloblepharon 0.5517127799736508 0.4766307763828777 0.6336250639483103 1.0 0.9793953163101812 4 O15111,O75569,P18074 3 +Bradykinesia 0.310756286047432 0.4731968737364982 0.6360727279680374 1.0 0.9813090515335828 26 O43464,Q6DKK2,Q86SQ9,Q96RR1,P12235,Q96RL7,P04062,Q06787,O75569 9 +Lissencephaly 0.2864821725833522 0.4717134876307723 0.6371313086282142 1.0 0.9813090515335828 54 O43505,Q9HC21,Q96EK5,P36543,P23786,Q9NP72,P57740,Q9BV10,Q15392,Q9BSJ2,Q08AM6,Q16134,O14936,Q6ZXV5,Q9H936,O95721,Q86XL3,Q9Y487,O43175,Q9Y320,Q15042,Q9NWS8 22 +Functional abnormality of male internal genitalia 0.3140435114379692 0.4710124569464401 0.6376318392423108 1.0 0.9813090515335828 25 P04062,Q13423,Q9Y4P3,P16435 4 +Rib fusion 0.4216511120939668 0.4702492203983979 0.6381769723189563 1.0 0.9813090515335828 8 Q5H8A4,Q9UM00,O95202 3 +Aplasia hypoplasia of the distal phalanges of the hand 0.3048784203515215 0.4678199611784158 0.639913344694047 1.0 0.9813090515335828 31 Q08AM6,P51812,P38435,P16435,O75844 5 +Abnormal circulating ige level 0.4319273836286091 0.4674941253611134 0.6401463941563121 1.0 0.9813090515335828 6 Q05655,O43909 2 +Fulminant hepatic failure 0.6353839146705073 0.4673500360478391 0.6402494633230202 1.0 0.9813090515335828 3 Q16836 1 +Cerebellar atrophy 0.2918280922961481 0.4673431194230364 0.6402544110592312 1.0 0.9813090515335828 127 Q5H8A4,Q6DKK2,Q96BR5,Q14108,Q10713,Q9BT22,O14773,Q8IV08,Q9BTW9,Q9GZY8,Q9H6K4,Q96RR1,P51572,P12235,P04350,O75648,O00400,Q13217,O14936,Q9Y3E5,P13073,Q9NVI7,O75503,Q8N766,Q9H936,O60313,O00754,P00387,P51798,Q96D71,O00429,Q5JRX3,Q9H9P8,P46977,Q92643,Q96CU9,Q6PI48,Q06787,O60762,Q96S52,Q9Y320,Q14671,Q9Y5Y5,Q9UBB4,Q5XKP0 45 +Reduced subcutaneous adipose tissue 0.4058489258545015 0.4668359618505663 0.6406172445654965 1.0 0.9813090515335828 9 O75844 1 +Abnormality of thyroid physiology 0.275313460360968 0.4665967594006769 0.6407884059411733 1.0 0.9813090515335828 70 P03886,O76024,O95470,P04066,Q96RR1,O60313,P12235,Q969G3,P56192,Q9Y4P3,Q07021,O00429,O60566,O43826,P21964,Q15645,Q13423 17 +Fat malabsorption 0.4056208610476576 0.4656478601404696 0.6414675791937898 1.0 0.9813090515335828 9 Q14739 1 +Ovarian gonadoblastoma 0.6287030941408838 0.4627582533442591 0.6435376577815615 1.0 0.9813090515335828 2 Q8IY37 1 +Female external genitalia in individual with 46 xy karyotype 0.6287030941408838 0.4627582533442591 0.6435376577815615 1.0 0.9813090515335828 2 Q8IY37 1 +Hypoplasia of the vagina 0.6287030941408838 0.4627582533442591 0.6435376577815615 1.0 0.9813090515335828 2 Q8IY37 1 +Abnormal sex determination 0.6287030941408838 0.4627582533442591 0.6435376577815615 1.0 0.9813090515335828 2 Q8IY37 1 +Gonadoblastoma 0.6287030941408838 0.4627582533442591 0.6435376577815615 1.0 0.9813090515335828 2 Q8IY37 1 +Abnormality of the palm 0.2775002707137167 0.4572913668166221 0.6474616341386563 1.0 0.9826912913707936 105 Q15907,Q9UHX1,P57740,O43909,Q06136,Q9NXE4,Q08AM6,P16435,Q6NUK1,P21912,Q8NCH0,Q96I36,P53634,O75381,O96028,O75431,P61978,P16615,Q9Y619,P10644,Q15555,O95721,P42345,Q9Y487,Q9H9E3,P51812,P40855,O95202,O60762,Q96S52,Q14739,P50542,Q9Y5Y5,O95831,Q9H4L7,P42167 36 +Abnormality of limb epiphysis morphology 0.3070210540983159 0.4565660178081192 0.647983009186949 1.0 0.9826912913707936 28 P51812,Q96L58,O96028,O95202,P16435,Q6NUQ1,P10644,O43909,P50542,O95831,Q5JRA6,Q9H9E3,Q7LGA3 13 +Nonimmune hydrops fetalis 0.305889666483482 0.4556898572607576 0.6486130166224586 1.0 0.9826912913707936 29 Q14739,Q9BT22,P04062,P10619 4 +Abnormal erythrocyte sedimentation rate 0.4183926691228314 0.4543416785926539 0.6495829222141078 1.0 0.9826912913707936 8 P28070 1 +Loss of ability to walk 0.3442733970542236 0.4523075052113124 0.651047469907551 1.0 0.9840924659397642 15 P00846 1 +Pectus carinatum 0.2987685237282103 0.4514875052332364 0.6516382283818625 1.0 0.9840924659397642 34 P51812,Q96L58,P16278,Q9BTW9,P55795,O00754,Q9Y619,Q96S52,Q9NVI7,Q9H9E3,P08236 11 +Pain 0.3078215294124267 0.4513132452388159 0.651763799955233 1.0 0.9840924659397642 159 Q9UGP8,P07602,Q9NZJ7,P23786,Q14108,P50402,P00846,P51530,Q15645,Q92804,P35637,P06280,Q9UHD9,Q9H6K4,Q96RR1,P12235,Q969G3,O15269,P04062,Q13510,P21912,Q9BW27,Q8N1F7,O75844,Q70HW3,P28070,O60313,Q15165,Q8NFH4,Q9Y4P3,Q01844,P42892,O00429,P21964,Q9NZ08,P22626,Q96HY6,Q15800,Q05655,Q14739,Q13423 41 +Persistent ebv viremia 0.6301612375505079 0.4506917659847586 0.652211717666106 1.0 0.9840924659397642 3 Q05655 1 +Lambdoidal craniosynostosis 0.6298467148565607 0.4496953341852769 0.6529301361136803 1.0 0.984154800921515 3 P16435 1 +Aplasia hypoplasia of the vagina 0.6289101086598604 0.4467327158789193 0.655068057173104 1.0 0.9862256248845692 3 Q8IY37,P30153 2 +Bone pain 0.3257663972281137 0.4466659236487308 0.6551162892967766 1.0 0.9862256248845692 20 P07602,Q9NZJ7,P04062 3 +Sepsis 0.3302294925059387 0.4456733899042059 0.655833188998411 1.0 0.9865691722069352 18 Q9BT22,Q9BV10 2 +Aplasia hypoplasia of the nails 0.280914839151566 0.4451546647172701 0.6562079865615178 1.0 0.9868066548325104 61 Q08AM6,P51812,Q9Y487,P23786,Q9Y4P3,P16615,Q6NUK1,Q14739,Q9BV10,O75844 10 +Lymphoproliferative disorder 0.4514338745484776 0.4448332034614736 0.6564402973007886 1.0 0.9868297793857528 5 Q05655 1 +Broad nasal tip 0.285151987808583 0.4438806252417899 0.6571288930015098 1.0 0.9869051189831438 46 P51812,O43924,Q9UHX1,Q9Y487,Q7LGA3 5 +Birth length less than 3rd percentile 0.6273219387902707 0.4417250211102927 0.6586882013324078 1.0 0.9869051189831438 3 Q9Y619 1 +Dental crowding 0.319545899537857 0.4397865853279746 0.660091684371801 1.0 0.9869051189831438 22 P51812,Q96A33,O75844 3 +Abnormal peripheral myelination 0.3003560796688723 0.4390437068996931 0.6606298671301676 1.0 0.9869051189831438 32 Q9NZJ7,P03886,P00846 3 +Severe muscular hypotonia 0.3002451326388124 0.4380395250901583 0.6613576317037737 1.0 0.9869051189831438 32 O43505,Q5H8A4,P40855,Q9GZY8,Q01105,Q9NWM8,O75381 7 +Narrow palate 0.2898448025959541 0.4338606806274861 0.664389613839697 1.0 0.9876432908009256 38 Q08AM6,P51812,P23786,P16435,Q9Y619 5 +Weakness of facial musculature 0.2832188223721296 0.4314434477547797 0.6661459641875851 1.0 0.9876432908009256 53 Q9UHX1,P51812,P40855,O60313,Q96RR1,P12235,O00429,Q13510,Q9Y5Y5,P51530,O75381 11 +Specific learning disability 0.2812535332005784 0.4299067607553506 0.6672634673132152 1.0 0.9876432908009256 58 O43505,P09651,O43909,Q10713,P35637,Q9BPX6,Q9H6K4,Q96RR1,P53701,P04350,P00367,Q8TC12,P03886,O00754,Q9Y619,P10644,Q9NX14,P42345,P21964,P22626,Q6PI48,P11166,Q06787,Q9Y4W2 24 +Macular thickening 0.414870439985346 0.4298479211888822 0.6673062710715729 1.0 0.9876432908009256 7 Q86SQ9 1 +Emg chronic denervation signs 0.3602381541838577 0.42959565331296 0.6674897995333635 1.0 0.9876432908009256 12 P07602,O60313,Q9NZJ7,Q13510 4 +Abnormal ureter morphology 0.3181843079048763 0.4293189580905884 0.6676911221091331 1.0 0.9876432908009256 22 O75844,P23786,Q7LGA3 3 +Neurogenic bladder 0.4475023222624239 0.4288988173506595 0.6679968609183502 1.0 0.9876432908009256 5 O76024 1 +Acute hepatic failure 0.347870932766388 0.4288200767630515 0.6680541670244995 1.0 0.9876432908009256 13 O75648,Q6NUQ1,P16930,P40939,Q16836,Q9P2J5 6 +Abnormal oral frenulum morphology 0.3599459860093782 0.4278391190715491 0.6687682540383824 1.0 0.9883777737558808 12 O75844 1 +Obstructive sleep apnea 0.3598647271367295 0.4273507687126019 0.6691238599109828 1.0 0.988524596514584 12 Q96A33 1 +Decreased calvarial ossification 0.537636095626604 0.426807536419915 0.6695195167864219 1.0 0.988524596514584 4 O75844 1 +Abnormal echocardiogram 0.6221255343889986 0.4254823799608732 0.6704850636496995 1.0 0.9888652785545564 3 P12235 1 +Cystic liver disease 0.4466424430121041 0.4254341538838465 0.670520212825529 1.0 0.9888652785545564 5 Q9UGP8 1 +Abnormal systemic blood pressure 0.2593544507561871 0.4245638829851453 0.6711546264077599 1.0 0.9888652785545564 82 Q08AM6,P03886,P07602,Q9NZJ7,Q9Y4P3,P16435,P42892,P04062,Q10713,P21964,O75844,Q13423 12 +Limb pain 0.3709897713528848 0.4244030132809567 0.6712719235384634 1.0 0.9888652785545564 11 O95140,P36551,O15269,P00846,O15270,O75569 6 +Premature ovarian insufficiency 0.3249427669587225 0.4233058749539853 0.6720721084651613 1.0 0.989347261645942 19 P49770,Q9NR50,Q96RR1,Q15031,P57740,Q05655,Q06787 7 +Abnormal mitochondrial number 0.6210137038333465 0.4220358611858387 0.672998842190853 1.0 0.989347261645942 3 P51530 1 +Megalocornea 0.3589107176070656 0.421623367588013 0.6732999472431982 1.0 0.989347261645942 12 Q5H8A4,Q9Y4P3 2 +Congenital sensorineural hearing impairment 0.4450581144243686 0.4190700803748095 0.6751649161327309 1.0 0.989347261645942 5 O76024 1 +Calf muscle pseudohypertrophy 0.615207373271891 0.4189901696474933 0.6752233167014039 1.0 0.989347261645942 2 Q9Y5P6 1 +Decreased cervical spine mobility 0.615207373271891 0.4189901696474933 0.6752233167014039 1.0 0.989347261645942 2 Q9Y5P6 1 +Abnormal muscle fiber alpha dystroglycan 0.615207373271891 0.4189901696474933 0.6752233167014039 1.0 0.989347261645942 2 Q9Y5P6 1 +Fusion of the cerebellar hemispheres 0.615207373271891 0.4189901696474933 0.6752233167014039 1.0 0.989347261645942 2 Q9Y5P6 1 +Abnormality of the tongue muscle 0.615207373271891 0.4189901696474933 0.6752233167014039 1.0 0.989347261645942 2 Q9Y5P6 1 +Generalized neonatal hypotonia 0.4210795131827164 0.4188901949168104 0.675296383251407 1.0 0.989347261645942 6 Q08AM6,Q9Y5Y5 2 +Limb girdle muscular dystrophy 0.4107015359705621 0.4171720303356488 0.6765525818272982 1.0 0.9907329260043862 8 O14979,P50402 2 +Dysarthria 0.3005543677570123 0.4107080732303439 0.6812866064235537 1.0 0.9910868168174723 150 Q6DKK2,Q13409,Q96BR5,O60220,P07602,Q9NZJ7,Q14108,Q10713,P00846,Q7KZN9,O14773,P61916,Q8IV08,P35637,Q9P0J0,Q9H6K4,P12235,P04062,P51648,P15586,O75503,O76024,O14653,Q9Y4P3,O75306,P49770,Q96CU9,Q9NR50,O75027,Q9NP80,Q5XKP0,O15118 32 +Limb ataxia 0.3125408979347068 0.4078377146338311 0.683392822858794 1.0 0.9910868168174723 23 Q14108,P04062,Q10713,Q8IV08 4 +Muscle spasm 0.2797238270593216 0.4069795359763158 0.6840230183225091 1.0 0.9910868168174723 57 Q5H8A4,P06280,Q9H6K4,Q9UHD9,Q96RR1,Q15165,P23786,P12235,P05023,P04062,P00846,P51530,Q92804,P35637 14 +Hypertrophic nerve changes 0.6105990783409982 0.4044738206679779 0.6858643252498133 1.0 0.9910868168174723 2 Q8TB36 1 +Hepatic cysts 0.5311471586653163 0.4044101536100608 0.6859111348948113 1.0 0.9910868168174723 4 Q9UGP8 1 +Cystoid macular edema 0.4411355764719012 0.4034251865761415 0.6866354612400578 1.0 0.9910868168174723 5 Q86SQ9 1 +Abnormal ossification involving the femoral head and neck 0.5307339376050462 0.4029967277873032 0.6869506317081395 1.0 0.9910868168174723 4 Q14739 1 +Aplasia hypoplasia of the skin 0.2807378888719541 0.4011501638407299 0.6883095698086077 1.0 0.9910868168174723 52 Q6ZXV5,Q5H8A4,Q96L58,Q15125,P53701,O96028,O95202,Q9Y619,Q13126,P10644,Q96PU5,Q15392,Q8NCH0,P53634,Q9H4L7,O75844,Q9NWM8 17 +Hyperventilation 0.4169930718622401 0.4008901979319658 0.6885009669520825 1.0 0.9910868168174723 6 P00846 1 +Short chin 0.3772165246820902 0.3981524831817086 0.6905177894937491 1.0 0.9910868168174723 10 O75844 1 +Leukodystrophy 0.2788818653126541 0.397258131496741 0.6911771186874662 1.0 0.9910868168174723 57 Q53FT3,P03886,Q96CU9,Q86Y39,P07602,Q9NZJ7,O96000,O43676,Q7KZN9 9 +Achilles tendon contracture 0.354600380842461 0.3958889131393448 0.6921869803333496 1.0 0.9910868168174723 12 Q9Y3E5,O60313,Q9BTV4,P50402 4 +Bilateral talipes equinovarus 0.4387429371256188 0.3939622713906117 0.6936088943539629 1.0 0.9910868168174723 5 O00754,Q15392 2 +Recurrent pharyngitis 0.6116207629672704 0.3933374032693447 0.6940702961128928 1.0 0.9910868168174723 3 Q9BV10 1 +Hypoplastic nipples 0.4056524775874651 0.3930820702661688 0.6942588663002942 1.0 0.9910868168174723 8 Q96A33 1 +Renovascular hypertension 0.3914476620969881 0.3927930292175021 0.6944723536118709 1.0 0.9910868168174723 9 Q08AM6 1 +Inguinal hernia 0.2704366349184688 0.3912626956286227 0.6956030699799358 1.0 0.9910868168174723 69 Q9UHX1,P51812,P16278,Q9Y4P3,Q10713,P21964,Q8NCH0,Q9Y487,P08236 9 +Congenital contracture 0.2796876898128866 0.3896297472713315 0.6968103520576507 1.0 0.9910868168174723 43 Q96A33,O75844,Q15392,Q8NCH0 4 +Fatty replacement of skeletal muscle 0.4061230245758261 0.389276347484607 0.6970717311360539 1.0 0.9910868168174723 7 Q8NFF5,P51114,P22626 3 +Abdominal distention 0.3152219107383267 0.3868677935222349 0.6988540852525855 1.0 0.9910868168174723 21 O43681,Q9UGP8,Q96HY6,P07602,Q9NZJ7,Q9Y6B6,Q01844,Q13277,P04062,O43826 10 +Abnormality of mouth size 0.2758479352264191 0.3867507075609699 0.6989407724602184 1.0 0.9910868168174723 110 P51812,P16278,O75844,P51571,P55795,P55201,Q9Y4P3,P16435,Q01105,Q9Y619,Q6NUK1,P04062,Q8NCH0,Q15392,P21964,Q9Y487,P15586,Q7LGA3 18 +Abnormal proportion of cd4 positive t cells 0.4055716199087948 0.3867462736093784 0.6989440553125028 1.0 0.9910868168174723 7 Q05655,Q9H0U3 2 +Aplasia hypoplasia of the uterus 0.3304141552637161 0.3863527873147466 0.6992354109403849 1.0 0.9910868168174723 16 Q16740,P53701,O96028,O95202,Q15031,P57740,Q9NX14 7 +Areflexia of lower limbs 0.3174814056109731 0.3856943572247918 0.6997230423843595 1.0 0.9910868168174723 20 O95140,P07196,Q9H6K4,O60313,Q96RR1,P12235,Q15067,Q96RL7,O75477,Q13217,Q15041,Q16637 12 +Hyperostosis 0.3405873128930969 0.3832319919542925 0.7015477592736314 1.0 0.9910868168174723 13 P51812,O00754,Q96L58,P22626 4 +Keratoconjunctivitis 0.389372734053598 0.3823031071168076 0.7022365502726191 1.0 0.9910868168174723 9 Q9NZ08 1 +Iris coloboma 0.2962683059299345 0.3812836516553907 0.7029927831899676 1.0 0.9910868168174723 30 O43505,Q9UHX1,Q5H8A4,P53701,Q10713 5 +Babinski sign 0.2563496375525135 0.381144589874007 0.7030959621388457 1.0 0.9910868168174723 82 P51812,Q6DKK2,Q9H6K4,Q99720,O60220,Q9NZJ7,P07602,O00400,P00846,O14773 10 +Keratitis 0.3740455794022963 0.3809634473682189 0.703230371706024 1.0 0.9910868168174723 10 Q9NZ08 1 +Abnormal morphology of the abdominal musculature 0.4026363325862111 0.3788177333301009 0.7048232178357845 1.0 0.9910868168174723 8 Q8NCH0 1 +Respiratory failure requiring assisted ventilation 0.4343656988429717 0.3768126628530869 0.706312829640956 1.0 0.9910868168174723 5 P10253,Q9BTW9 2 +Hypomimic face 0.3882447816610556 0.3766211532177976 0.7064551654266091 1.0 0.9910868168174723 9 P12235 1 +Abnormal bone structure 0.3073687027648712 0.3760205941343492 0.7069015857608192 1.0 0.9910868168174723 169 Q5H8A4,O75718,Q9HC21,Q96L58,P07602,Q9NZJ7,Q9UG56,Q14108,Q13126,O43909,O60566,Q9BV10,Q15392,O43826,Q15645,Q5JRA6,P08236,Q08AM6,P06280,P16278,Q96RR1,P12235,Q6NUK1,P07237,P04062,Q13510,P21912,O75844,Q9NWM8,O75381,Q9Y5U9,O00754,Q9Y4P3,Q9Y619,P16930,Q86WC4,Q86XL3,Q9Y487,P22626,Q9HC07,P38435,P40855,Q96HY6,O95202,Q13277,Q14739,Q9Y5Y5,P54802 48 +Prominent nasal bridge 0.2799742836532694 0.3755811132882521 0.7072283338925232 1.0 0.9910868168174723 40 O43924,P42892,Q9BV10,P21964,P13073 5 +Irregular menstruation 0.4340248747034697 0.3754863575813499 0.707298790563663 1.0 0.9910868168174723 5 P10644,O43826 2 +Middle age onset 0.3729391675855102 0.3749942342328328 0.7076647547189705 1.0 0.9910868168174723 10 Q9NZJ7 1 +Short palm 0.3202315347560968 0.3748685785210665 0.7077582085555316 1.0 0.9910868168174723 18 Q9UHX1 1 +Status epilepticus 0.2787107821221932 0.374813045837804 0.7077995112428068 1.0 0.9910868168174723 49 Q86SQ9,Q3ZCQ8,P07602,Q9NZJ7,Q96RR1,P53701,Q9H2C2,Q01105,P42892,P05023,Q96S52,O00429,Q15392,Q13510,Q9Y487 15 +Prematurely aged appearance 0.2838260113447545 0.3747284149945413 0.7078624574731063 1.0 0.9910868168174723 38 Q9Y487,Q13126,O75844,Q9Y4P3 4 +Developmental regression 0.2836416912042424 0.3745532121480674 0.7079927751583481 1.0 0.9910868168174723 124 Q86SQ9,P07602,Q9NZJ7,P55795,Q9H2C2,P00846,O14773,Q08AM6,P06280,P16278,Q9GZY8,O95470,P17900,Q13510,P13073,O75381,O75503,P03886,O76024,Q9Y4P3,Q9NVH6,Q15067,O00429,Q9NZ08,O75306,P40855,P49770,Q9NR50 28 +Aplasia hypoplasia of the capital femoral epiphysis 0.4337823010137953 0.3745431958300369 0.7080002256575335 1.0 0.9910868168174723 5 Q7LGA3 1 +Mixed demyelinating and axonal polyneuropathy 0.5222406316939286 0.3742998237918064 0.7081812631600044 1.0 0.9910868168174723 4 P03886,P07196 2 +Reduced forced expiratory volume in one second 0.6007241606319857 0.3741422343707443 0.7082984982232785 1.0 0.9910868168174723 2 Q96J02 1 +Myopathy 0.2629486502398387 0.3738830008423642 0.7084913641438302 1.0 0.9910868168174723 92 Q86Y39,P23786,Q07021,P46976,Q13126,P50402,P00846,Q00325,P51530,Q96RR1,Q53H12,P12235,P21912,Q8NCH0,P15291,Q9NWM8,P03886,O76024,O60313,O00754,Q9Y4P3,O43676,O14979,O00429,P22626,O75306,P42167 27 +Distal peripheral sensory neuropathy 0.4332721883332464 0.3725619958775369 0.7094744624594469 1.0 0.9910868168174723 5 P03886,P40939 2 +Abnormal renal vascular morphology 0.521399364456711 0.3714950689950004 0.7102688279848486 1.0 0.9910868168174723 4 Q08AM6 1 +Abnormality of the glabella 0.4327177442533446 0.3704120030955483 0.7110755316831292 1.0 0.9910868168174723 5 O95202,O60762 2 +Hypoplasia of teeth 0.3195730657869329 0.3702634013347536 0.7111862405152873 1.0 0.9910868168174723 18 P51648 1 +Arthrogryposis multiplex congenita 0.2868590971245723 0.3700315876833467 0.7113589546597612 1.0 0.9910868168174723 36 O75844,Q15392,Q8NCH0 3 +Abnormal femoral head morphology 0.3174928201337345 0.3698131050100195 0.7115217500418458 1.0 0.9910868168174723 19 Q96L58,P16278,O75431,Q6NUQ1,O43909,P50542,O95831,Q7LGA3 8 +Abnormality of pancreas physiology 0.2813753722534209 0.3694401347466706 0.7117996873051986 1.0 0.9910868168174723 39 Q9NZ08,P09601,Q9UHX1,Q14739 4 +Arachnodactyly 0.2937909882092977 0.3693260480815279 0.7118847122849632 1.0 0.9910868168174723 31 Q5H8A4,Q96L58,P55795,O95202,P16435,P21964,Q8NCH0 7 +Hypermetropia 0.2778228582852874 0.3649431507618124 0.7151538427673003 1.0 0.9924450368360126 48 Q15907,Q96A33,Q9UHX1,Q5H8A4,Q9Y4P3 5 +Abnormal pulmonary valve morphology 0.3488631284082621 0.3620217300714819 0.7173357920250727 1.0 0.9936542381005042 12 Q9BUB7,P21964 2 +Abnormality of adrenal physiology 0.2948127288267343 0.3601788831826085 0.7187133652337796 1.0 0.9945539175734806 29 P40855,O95470,Q969G3,P16435,Q9Y5Y5,Q13423,O75381 7 +Mild short stature 0.60029997590378 0.3597872178428402 0.7190062626679015 1.0 0.9945539175734806 3 Q14739 1 +Wide nasal ridge 0.5174571805006495 0.3584453915781691 0.7200100276296479 1.0 0.99504600899989 4 P27635,Q15022,P61978 3 +Delayed puberty 0.2769826854320401 0.3579427253363643 0.7203861759599588 1.0 0.9951523578626944 51 P06280,O76024,Q9UJS0,Q15800,P16435,Q14108,P04062,O43826,O00429,O75844,Q9NVI7 11 +Abnormal systemic arterial morphology 0.2865453517374288 0.3574263377515176 0.7207726625387982 1.0 0.9953839835728576 131 Q9UHX1,Q96L58,P07602,Q9NZJ7,P10253,P00846,P61916,Q08AM6,P16278,P17900,Q6NUK1,P04062,Q13510,O75844,Q9NWM8,Q6ZXV5,P03886,Q9Y4P3,P10619,P21964,Q7LGA3,P38435,P06865,P05067,O15118 25 +Abnormality of the septum pellucidum 0.2819437202376336 0.3563926543640452 0.7215465296909611 1.0 0.9956906787115822 38 Q9NZ01,O43505,Q13409,P51571,P53701,Q96N66,O96028,O95202,O43175,Q9BV10,Q15392,P55011 12 +Atrophy degeneration involving the spinal cord 0.3977413253345534 0.3558802081542692 0.7219302783513055 1.0 0.9956906787115822 8 Q96RR1,P07196,Q13217 3 +Aplasia hypoplasia involving the femoral head and neck 0.3837356689430918 0.3540562768478517 0.7232967083926922 1.0 0.9956906787115822 9 O75431,Q96HY6,Q96L58,P50542 4 +Ineffective esophageal peristalsis 0.4283691363673213 0.3536734613850037 0.723583613499287 1.0 0.9956906787115822 5 P06280 1 +Aplasia involving bones of the extremities 0.5981737288539506 0.3536181194735082 0.723625093296286 1.0 0.9956906787115822 3 Q08AM6 1 +Aplasia of the phalanges of the hand 0.5981737288539506 0.3536181194735082 0.723625093296286 1.0 0.9956906787115822 3 Q08AM6 1 +Diffuse mesangial sclerosis 0.3214195252519601 0.3532489011031679 0.7239018501338226 1.0 0.9956906787115822 17 O95470,Q8N1F7,Q8NFH4,Q9BW27 4 +Hallux valgus 0.3210317177736354 0.3506281067545406 0.7258673674966929 1.0 0.9973046024488814 17 P04062,Q9Y4P3 2 +Extra axial cerebrospinal fluid accumulation 0.5921658986175133 0.3487446733004733 0.7272810028462444 1.0 0.9982847292210588 2 Q03252 1 +Soft skin 0.3826132104394424 0.3484774882691456 0.7274816173593779 1.0 0.9982847292210588 9 Q13126,Q9NWM8,Q96L58 3 +Abnormal mitochondrial shape 0.4261370474194441 0.3451692092718268 0.7299671653195197 1.0 0.9996661739171486 5 Q9GZY8 1 +Gastroparesis 0.3950550643807031 0.3434095498655992 0.7312903761314791 1.0 0.9996661739171486 8 O43464,Q96RR1,P12235,Q9BUB7 4 +Moderate albuminuria 0.5126779335619132 0.3428359555546402 0.7317218747869818 1.0 0.9996661739171486 4 Q9Y5U9 1 +Abnormality of facial soft tissue 0.2708168112970021 0.3422131727594511 0.7321904726235227 1.0 0.9996661739171486 107 Q15907,Q9UHX1,P10253,P51530,Q96RR1,P12235,Q969G3,P16435,P04062,Q13510,P21912,Q9BW27,Q8N1F7,O75844,O75381,P28070,O60313,Q8NFH4,Q9Y4P3,O00429,P51812,P40855,Q9Y5Y5 23 +Telangiectasia of the skin 0.3134313755385495 0.3410661758724895 0.7330537639156471 1.0 0.9996661739171486 19 Q14739,Q8IZA0,P06280 3 +Abnormality of the skull base 0.2748988077405526 0.3410006851074292 0.7331030659767777 1.0 0.9996661739171486 54 O43505,Q9UHX1,Q9NPL8,Q96L58,P23786,Q969G3,Q14739,Q10713,O60566,Q15645,P15291,Q9Y487 12 +Abnormality of globe size 0.2735815987114278 0.3408634628036773 0.7332063717820785 1.0 0.9996661739171486 58 O43505,Q9UHX1,Q08AM6,Q9BXW9,O43924,Q15125,P53701,O75431,Q15555,Q6NUK1,O60566,P21964,Q96I36,Q15645,Q15042,O75569 16 +Generalized limb muscle atrophy 0.3944591029023844 0.3406544797249917 0.733363710920496 1.0 0.9996661739171486 8 O43819,P06753,Q8IY17,Q6PI48,Q9Y2U8,Q9Y5P6,Q9Y2Z4 7 +Abnormal leukocyte physiology 0.2735488649710585 0.3404863335629893 0.7334903129016426 1.0 0.9996661739171486 58 O60220,P09601,P28070,Q14108,Q9UJW0,Q05655,P04062,Q9BV10,P21964 9 +Abnormal oral physiology 0.2750663373077919 0.3404167742581722 0.7335426881810161 1.0 0.9996661739171486 53 Q08AM6,P51812,Q9UHD9,P55795,Q15165,P55011,Q96RL7,P10644,O43909,Q14739,Q92804,P15586,P35637 13 +Infantile muscular hypotonia 0.2708130278239144 0.3386949644345283 0.7348395344945962 1.0 1.0 63 O75306,P03886,Q9GZY8,P16278,P07602,Q9NZJ7,P17900,O00754,Q969G3,P10253,O43909,P00846,Q13510,Q9Y487,Q9BTW9 15 +Diarrhea 0.269288284261431 0.3363205600812584 0.7366291473271982 1.0 1.0 65 O43464,Q15904,O43826,Q9BT22,Q96A33,P06280,Q13510,P15586,P03886,P50416,P35610,P42892,Q9H9E3,Q9UJS0,O60762,Q13277,Q16836,Q13423,P54802 19 +Tongue fasciculations 0.3656819183771796 0.3362270743298909 0.7366996378054087 1.0 1.0 10 P51114,Q13510,O95831,Q16637,Q9BTW9 5 +Micrographia 0.5917664596561178 0.3352901221292141 0.7374062443270872 1.0 1.0 3 P04062 1 +Type i transferrin isoform profile 0.3794074803989435 0.3326320251045929 0.7394120661207615 1.0 1.0 9 P51571,Q9BT22,Q9H0U3 3 +Mortality aging 0.2681726970939521 0.3324016289403282 0.7395860086939838 1.0 1.0 104 O43464,O75718,Q9HC21,Q15904,P07602,Q9NZJ7,O96000,Q9BUB7,Q6NUQ1,Q9BT22,Q9NXE4,P16278,Q16134,P16435,Q6NUK1,P04062,O75844,Q9NVI7,O75381,Q9H936,O75431,Q9Y4P3,Q15067,Q86WC4,O95721,O00429,P51812,Q9NPL8,P40855,O43175,Q13277,Q14739,P50542,Q9Y5Y5,P05067 35 +Stroke 0.287082871034069 0.3315093139337446 0.7402598068652841 1.0 1.0 33 P03886,P06280,O76024,Q9Y4P3,O75844,P05067 6 +Decreased plasma carnitine 0.3645325887343268 0.3301520092908859 0.7412851065740411 1.0 1.0 10 P23786,Q16836 2 +Cyanosis 0.3174441930145528 0.3265166679950172 0.7440334804947999 1.0 1.0 17 O75844,P00387 2 +Chordee 0.39162920327564 0.323959589472298 0.745968628647592 1.0 1.0 7 P16435 1 +Gastritis 0.4204124702736322 0.3236396537407074 0.7462108630065314 1.0 1.0 5 P49327,Q05655 2 +Short nose 0.2566304257214953 0.3234342367807394 0.7463664044841005 1.0 1.0 88 Q9UHX1,O75844,Q9Y4P3,P16435,P42892,P04062,Q15392,Q8NCH0,Q9Y487 9 +Ventricular septal hypertrophy 0.5868088401072582 0.3213852437177057 0.7479184642873136 1.0 1.0 3 P06280 1 +Abnormal circulating bilirubin concentration 0.2909990638988574 0.3209984985678591 0.748211528716975 1.0 1.0 28 Q14739,Q86WC4,P23786 3 +Abnormality of carpal bone ossification 0.3982530574989902 0.3208088273071965 0.74835526948169 1.0 1.0 6 Q15125,O43909,Q96L58 3 +Epiphyseal dysplasia 0.3979149194715464 0.3194042280042627 0.7494200051265059 1.0 1.0 6 Q9HC07,Q96L58 2 +Syncope 0.351984084807585 0.3176839206742366 0.7507247092998965 1.0 1.0 11 Q9HD47 1 +Tetraplegia tetraparesis 0.2732189331041573 0.3173026676840269 0.7510139533561522 1.0 1.0 46 P07602,P17900,Q9NZJ7,P00846,Q9UBX3,Q13423 6 +Dysphagia 0.284196595944742 0.3154210654712304 0.7524419746193907 1.0 1.0 132 Q9UHX1,Q8IZA0,O60220,Q99720,P07602,Q9NZJ7,Q14108,P00846,P61916,Q9BTW9,P35637,Q08AM6,Q9GZY8,Q9UHD9,Q96RR1,P12235,P04062,Q13510,P15586,P03886,O76024,O60313,Q15067,O00429,O75306,Q01105,Q14739,Q9Y5Y5,P05067,O15118 30 +Panniculitis 0.3889545321972399 0.3154139816082703 0.7524473524438404 1.0 1.0 8 P28070 1 +Delayed gross motor development 0.2656386340654589 0.3150602967302307 0.7527158730770913 1.0 1.0 102 Q15907,Q5H8A4,Q13409,Q99720,Q96N66,O43909,Q9BV10,Q10713,P10253,P35637,Q9P2J5,P55201,O60783,P21912,Q8NCH0,Q6ZXV5,Q3ZCQ8,O94905,Q10471,Q7LGA3,Q01105,Q15042,P55011 23 +Eeg with polyspike wave complexes 0.3893349329495066 0.313861287755877 0.7536263935992149 1.0 1.0 7 Q14108,P11166,P04080 3 +Abnormal pyramidal sign 0.2751552971952085 0.3136878299103247 0.7537581448938848 1.0 1.0 117 Q9NZ08,P51812,Q6DKK2,Q9H6K4,Q99720,O60220,Q9NZJ7,P17900,P07602,Q9Y619,O00400,P00846,P51648,O14773,P35637 15 +Agnosia 0.3959003707920573 0.3110677783717704 0.7557490959291855 1.0 1.0 6 P05067 1 +Progressive muscle weakness 0.3400064118289868 0.3107037351225308 0.756025857489572 1.0 1.0 12 O75381,P40855,Q9Y5Y5 3 +Bilateral cleft palate 0.5786701777485176 0.3104614306144023 0.7562100853029516 1.0 1.0 2 O60716 1 +Bilateral cleft lip and palate 0.5786701777485176 0.3104614306144023 0.7562100853029516 1.0 1.0 2 O60716 1 +Non midline cleft palate 0.5786701777485176 0.3104614306144023 0.7562100853029516 1.0 1.0 2 O60716 1 +Difficulty walking 0.2569523307171536 0.3094626524126866 0.7569696178010206 1.0 1.0 76 Q15907,Q9HC21,Q86SQ9,P07602,Q99720,Q9NZJ7,O14653,Q9H2C2,Q15067,P00846,Q13510,P51530,O14773,P35637 14 +Death in adulthood 0.328377582574302 0.3086341672059272 0.7575998271996529 1.0 1.0 13 P05067,Q9Y4P3 2 +Red eye 0.3146768894261478 0.3080888258802033 0.7580147436245779 1.0 1.0 17 Q9NZ08,Q14739 2 +Deformed sella turcica 0.4158289050654004 0.3067034020561641 0.7590691400477367 1.0 1.0 5 P08236 1 +Abnormal iris pigmentation 0.3103329618622844 0.3065049585969732 0.7592202049866472 1.0 1.0 18 P40855,Q9Y4P3,P10644,Q9Y5Y5,P50542,O75381 6 +Cerebral hemorrhage 0.3498471711405276 0.3060055739088386 0.7596004018616758 1.0 1.0 11 P23786,Q969G3,P05067 3 +Abnormality of the spinal cord 0.2650905350195653 0.302806288790907 0.7620374905321592 1.0 1.0 67 Q9UHX1,Q5H8A4,Q9HC21,Q96L58,O43909,Q10713,P51530,Q9BXW9,P16278,Q96RR1,O00400,Q13217,O00754,O96028,Q9Y4P3,P21964,Q6PI48,O95202,P05067 19 +Absent epiphyses 0.3936077392086362 0.3016479190927507 0.7629204743272271 1.0 1.0 6 Q7LGA3 1 +Abnormality of the ureter 0.2697184269556978 0.3011604951414668 0.7632921124792336 1.0 1.0 59 Q9UHX1,O76024,P23786,Q9Y4P3,P16435,P21964,O75844,Q7LGA3 8 +Abnormal renal insterstitial morphology 0.3241667370807838 0.3010823479566054 0.763351701159394 1.0 1.0 14 P23786,Q9Y4P3 2 +Red green dyschromatopsia 0.5791010018716451 0.3002608278253509 0.7639782102989796 1.0 1.0 3 Q9H6K4 1 +Aphasia 0.2807783075307553 0.2992001043194011 0.7647873697026788 1.0 1.0 35 P03886,P53701,O00429,P21964,P05067,P22626,Q7LGA3 7 +Tachycardia 0.2895750095401287 0.2988427655069562 0.765060018938728 1.0 1.0 26 P0DP25,P23786,Q9HD47 3 +Cessation of head growth 0.413334651312146 0.2976040326381567 0.7660053963713471 1.0 1.0 5 Q9NR50 1 +Diminished motivation 0.3006381916428935 0.2974524728199771 0.7661210879103058 1.0 1.0 22 O43464,P35610,P17900,Q96RL7,P04062,P06865,Q9UBB4,P35637 8 +Abnormality of dental morphology 0.2694935699900172 0.2939781584045937 0.7687745933769736 1.0 1.0 58 Q96A33,P51812,Q9Y4P3,Q9Y619,Q6NUK1,P07237,Q9Y487,Q7LGA3 8 +Abnormality of bone mineral density 0.2808772684384233 0.292641913384242 0.7697958732799723 1.0 1.0 129 Q5H8A4,Q9HC21,Q96L58,P07602,Q9NZJ7,Q14108,Q13126,Q15392,P06280,P16278,P12235,P07237,P04062,Q13510,O75844,Q9NWM8,Q9Y5U9,Q9Y4P3,Q86WC4,Q9Y487,Q9HC07,Q96HY6,Q13277,Q14739,P54802 25 +Dilated fourth ventricle 0.2716388218312304 0.2923425534100803 0.7700247262092152 1.0 1.0 40 O43505,Q99567,O60826,P36543,Q15125,P23786,Q9Y5P6,Q969G3,Q96KP1,P21281,O43175,Q10713,O60566,O14936,Q8WVX9,Q15645,P15291,Q9Y487 18 +Megaloblastic anemia 0.3831168091750315 0.2890728582145952 0.7725256233469928 1.0 1.0 8 P00374 1 +Apnea 0.2504982739340118 0.2884952853326467 0.7729676389363529 1.0 1.0 80 Q86Y39,P07602,Q9NZJ7,P23786,O60566,P00846,O75880,P51530,Q10713,Q7KZN9,Q9P0J0,Q96A33,P04062,O43924,P03886,O76024,O60313,O75306,P51812,Q96CU9 20 +Albuminuria 0.4106214870932322 0.2878020522415935 0.7734982663441379 1.0 1.0 5 Q9Y5U9 1 +Abnormality of the musculature of the lower limbs 0.2941102746372031 0.2877605233593889 0.773530057519737 1.0 1.0 24 Q6PI48,Q9BTV4,Q96RL7,O14979,P50402,P00846,Q9NRG9 7 +Periauricular skin pits 0.3698449356648073 0.2861841065589617 0.7747371160355399 1.0 1.0 9 Q9Y2W2,Q9ULC3,O96028,O95202,P61978,P19367,P08754,Q8N3U4 8 +Moderate sensorineural hearing impairment 0.3822491031863048 0.2851968873646647 0.7754933049079187 1.0 1.0 8 Q9NP80 1 +Congenital malformation of the right heart 0.3823319327129677 0.2834817142246018 0.7768075969472574 1.0 1.0 7 P21281,P40855,O15460 3 +Relative macrocephaly 0.282100408053024 0.2772326411783964 0.7816014774760911 1.0 1.0 32 O75844,Q7LGA3 2 +Bowing of the legs 0.2692980463298039 0.2752324324905043 0.7831376712862177 1.0 1.0 47 Q96L58,P16278,Q96HY6,Q9NX62,Q9Y4P3,P16435,Q9Y619,Q13126,P08236,Q7LGA3 10 +Thickened calvaria 0.3798325405538846 0.2744577820396759 0.7837328433842807 1.0 1.0 8 P51812,P16278 2 +Abnormal nasal base 0.3436777814460173 0.2727053132488317 0.785079750082627 1.0 1.0 11 P51532,Q08AM6,P21281,Q969G3,Q93008,Q8TAQ2,Q92785,Q96ST3,Q13868,Q96GM5 10 +Tracheal stenosis 0.4059676771937603 0.2712279585766332 0.7862157108028884 1.0 1.0 5 O43909,Q96HY6 2 +Non hodgkin lymphoma 0.3531687809324917 0.2711286171401034 0.7862921123224393 1.0 1.0 10 Q05655 1 +Prenatal movement abnormality 0.2670656873190193 0.2706829538879328 0.7866348883641305 1.0 1.0 59 Q5H8A4,Q4J6C6,Q9HC21,P40855,Q86SQ9,Q9H2C2,P04062,O00429,Q7KZN9,P51530,O75844,Q70HW3 12 +Abnormality of facial musculature 0.2591648607948822 0.270517665744825 0.7867620280861614 1.0 1.0 71 Q15907,Q9UHX1,P51812,P40855,O60313,Q96RR1,P12235,Q969G3,P10253,P04062,Q13510,O00429,P51530,Q9Y5Y5,O75381 15 +Abnormal qt interval 0.3664590322710093 0.270052355916727 0.7871199751561042 1.0 1.0 9 P0DP25 1 +Hypercholesterolemia 0.3217215968680597 0.2690823825798462 0.787866287281302 1.0 1.0 13 Q9UJS0,Q15904,O75431,Q13045,O43826,Q8N511,Q9H9E3 7 +Abnormal renal pelvis morphology 0.2686919056862636 0.2680497733937736 0.788661006450118 1.0 1.0 48 O43505,O75718,P40855,O76024,Q15125,P23786,P16435,P61978,Q9Y5Y5,Q8NCH0,Q15042,Q5JRA6,O75381 13 +Preaxial foot polydactyly 0.5655901183363136 0.2647425129350086 0.7912078250239292 1.0 1.0 3 O95202 1 +Temporal pattern 0.3772884905649725 0.2620388890725164 0.7932914602594427 1.0 1.0 7 P04062 1 +Neuropathic arthropathy 0.4864326661657807 0.2615700765308629 0.7936529164462005 1.0 1.0 4 O15269 1 +Duodenal adenocarcinoma 0.5595786701777503 0.2602144918781289 0.7946983263106713 1.0 1.0 2 P78549 1 +Paresthesia 0.2904579345937243 0.2601138337774554 0.7947759673064332 1.0 1.0 24 Q9NZ08,P06280,P05067,Q9H6K4 4 +Head tremor 0.3201716549755886 0.2599977697372266 0.7948654939474991 1.0 1.0 13 Q99720 1 +Congenital malformation of the left heart 0.4858366271409789 0.2598177424499698 0.795004364338671 1.0 1.0 4 O60826,P24468,O14802 3 +Increased ldl cholesterol concentration 0.3763553379174276 0.2591520775347699 0.7955179048066883 1.0 1.0 8 Q8N511,Q9UJS0,P50402 3 +Hyperlipoproteinemia 0.3763553379174276 0.2591520775347699 0.7955179048066883 1.0 1.0 8 Q8N511,Q9UJS0,P50402 3 +Hypopigmentation of the skin 0.2662479794597234 0.2582606269986672 0.7962057708262578 1.0 1.0 41 Q9BXW9,Q8IZA0,P07602,Q15125,Q9NZJ7,P53701,P51798,P49327,P53634,Q6PGP7,P42345,P21964,P21912,O14617 14 +Abnormality of the inner ear 0.3638287539057942 0.2576415631656812 0.7966835495187423 1.0 1.0 9 Q9Y619 1 +Wormian bones 0.3029533761446817 0.2568782193965663 0.7972727849268257 1.0 1.0 18 Q9Y487,O75844 2 +Aplasia hypoplasia of the scapulae 0.4842752866884249 0.2552481442468201 0.7985314484790986 1.0 1.0 4 Q08AM6 1 +Contractures of the joints of the lower limbs 0.2673997894397348 0.2542335072024947 0.7993151658027955 1.0 1.0 51 Q8IZA0,Q9HC21,Q99720,O60313,P23786,O60762,O94905,P50402,P21912,Q86XL3,P37268,Q7LGA3,P35637 13 +Broad thumb 0.2836721920450726 0.2520855190802794 0.8009749627016935 1.0 1.0 26 Q9UHX1 1 +Antineutrophil antibody positivity 0.482844086521726 0.2510858993112289 0.8017476974929905 1.0 1.0 4 P49327,Q05655 2 +Abnormal bronchus morphology 0.2984620139749685 0.2506854920008814 0.8020572782947086 1.0 1.0 20 Q96HY6,P16435,Q13277,Q05655,Q03518 5 +Adenocarcinoma of the small intestine 0.5597629239380874 0.2500400190445004 0.8025564006118284 1.0 1.0 3 Q6PD74,P78549 2 +Abnormality of the achilles tendon 0.3155941451629371 0.2493038171726364 0.8031257788506498 1.0 1.0 14 Q15041,O60313,Q9BTV4,P50402 4 +Hydrocele testis 0.5593549952612552 0.2490250514948366 0.8033414034114836 1.0 1.0 3 Q9UBX3 1 +Hemiplegia hemiparesis 0.2777037165930138 0.2488609104141101 0.8034683731335075 1.0 1.0 33 P03886,P04637,P50416,O60313,Q969G3,Q9NP80,P49327,P57740,O00429,P42345,P11166,Q9NZ08 12 +Craniofacial hyperostosis 0.3993734696357266 0.2482785001861466 0.8039189326783736 1.0 1.0 5 P51812 1 +Cerebral cortical atrophy 0.2540976440819347 0.2474936684174832 0.8045261909900858 1.0 1.0 92 O75503,O43924,P03886,Q9Y4P3,P00387,Q9Y619,P04062,P00846,P05067,Q7LGA3 10 +Broad columella 0.4814203595702864 0.2469706991789477 0.8049309004413272 1.0 1.0 4 P36543 1 +Limited elbow extension 0.3614667762474153 0.2465897932484196 0.805225704474084 1.0 1.0 9 P16435,Q9H6K4 2 +Ovarian cyst 0.3087612413492314 0.2461424254936262 0.805571982322749 1.0 1.0 16 P16435,O43826,Q9Y4P3,P21912 4 +Abnormality of the knee 0.2482826787121536 0.2451371507025546 0.8063502382007299 1.0 1.0 84 Q96L58,P23786,Q5JRA6,P08236,P16278,Q96PU5,Q13510,P21912,Q6ZXV5,O00754,Q9NX62,Q9Y4P3,Q9Y619,O94905,P21964,Q86XL3,Q15041,P37268,Q7LGA3,Q96HY6 20 +Periorbital fullness 0.3049802236455826 0.2448108869509708 0.8066028638173148 1.0 1.0 17 P51812,Q7LGA3 2 +Proximal amyotrophy 0.3116951696310387 0.2439674137131644 0.8072560575491805 1.0 1.0 15 O14979,Q16637,P50402,P35637 4 +Neoplasm of the oral cavity 0.360794311861998 0.2434597688409905 0.8076492474143007 1.0 1.0 9 O43924,Q05655 2 +Abnormal tongue physiology 0.3047430729037915 0.2432904010747177 0.8077804398752537 1.0 1.0 17 P51114,P04350,P10253,Q13510,O95831,Q16637,Q9BTW9 7 +Complete duplication of phalanx of hand 0.3976935749588212 0.2425354780585765 0.8083652697868688 1.0 1.0 5 Q9Y2U8,P34897,Q9BXW9,P41227 4 +Bone spicule pigmentation of the retina 0.3725650128491548 0.2423067210452759 0.8085425062894513 1.0 1.0 7 Q9UG56,Q15555 2 +Recurrent otitis media 0.2905848968673203 0.2419092557269311 0.8088504780779453 1.0 1.0 23 Q05655,Q14739,Q8N5M9 3 +Abnormality on pulmonary function testing 0.3043121831209159 0.2405312659618567 0.8099184278514793 1.0 1.0 17 Q05655,Q96L58,P16278 3 +Coxa vara 0.3274307957648216 0.2401545153381296 0.8102104734011983 1.0 1.0 12 O75718,Q96HY6,Q9NUQ7,P50542,O95831,Q9Y487 6 +Peters anomaly 0.5551531116233046 0.2386803757761467 0.811353434873991 1.0 1.0 3 Q9H9S5,P19022 2 +Abnormal aortic valve cusp morphology 0.2874353485002099 0.2375062217663296 0.8122640930052929 1.0 1.0 24 Q9UHX1,Q6NUK1,Q96L58,Q9Y4P3 4 +Ventricular escape rhythm 0.39576979340948 0.2360114872280027 0.8134237564238849 1.0 1.0 5 P50402 1 +Limitation of joint mobility 0.2532657434884251 0.2357306983633233 0.8136416472356189 1.0 1.0 92 Q9HC21,P16278,Q9H6K4,O76024,P54802,P23786,Q9Y4P3,P16435,O14979,P51648,Q9BT22,O75844,P08236,P15586,Q7LGA3 15 +Intellectual disability progressive 0.3453222028663751 0.2315856074441682 0.8168598872390134 1.0 1.0 10 P53701,Q15067,O95721,O95831,Q9H9P8 5 +Talipes valgus 0.3940691927512407 0.2302918565952648 0.817864988070734 1.0 1.0 5 O00754,Q9HD42,Q15233,Q9H2M9 4 +2 3 toe syndactyly 0.2837303146862111 0.2300642653340043 0.818041832246476 1.0 1.0 25 O43924,Q9UHX1 2 +Episodic tachypnea 0.3694678754969659 0.2295602334639492 0.8184335107278442 1.0 1.0 7 O43924 1 +Metaphyseal dysplasia 0.3353335073445213 0.228727604270682 0.8190806383641778 1.0 1.0 11 Q9HC07,O43909,O95831 3 +High anterior hairline 0.3021939767663951 0.2270343751428113 0.8203970125046056 1.0 1.0 17 Q7LGA3 1 +Decreased circulating androgen concentration 0.3682965719926186 0.2243795511376931 0.8224619808897662 1.0 1.0 8 P16435,Q969G3,P16870 3 +Hyperpituitarism 0.3050740732346189 0.2232599881000833 0.823333166188096 1.0 1.0 16 Q969G3,P16435,Q15031,P57740,P10644,Q06787,Q8IY37 7 +Broad philtrum 0.343564356435637 0.2228752666803256 0.8236325865700387 1.0 1.0 10 P51532,Q969G3,Q96CW1,Q8TAQ2,Q92785,P11166,Q01082,Q9UM00,Q96GM5 9 +Cardiac arrest 0.276483994404739 0.2211675889313678 0.824961944652066 1.0 1.0 31 P0DP25,P04062,Q9HD47 3 +Impaired visuospatial constructive cognition 0.3673527287434794 0.2203737588495372 0.82558008047577 1.0 1.0 8 P03886 1 +Pectus excavatum 0.2512736257944824 0.2188215516794328 0.8267890578843895 1.0 1.0 75 Q9UHX1,O75718,Q96L58,Q9BTV4,O43909,P50402,Q9BTW9,Q96A33,P04062,P21912,Q8NCH0,O00754,O75431,Q9Y4P3,P61978,Q15555,Q9Y487,Q9H9E3,Q7LGA3,P51812,Q03164 21 +Hypoplasia of the uterus 0.3549044638965418 0.2163675040914396 0.8287012943034724 1.0 1.0 9 Q16740,P57740,Q15031,P53701 4 +Craniofacial dysostosis 0.3880887987927099 0.2105394264306957 0.8332466833344936 1.0 1.0 5 Q6NUK1 1 +Synostosis involving digits 0.4680500658761549 0.2095894183946139 0.8339881391147115 1.0 1.0 4 Q15233,Q9H1A4,P48651 3 +Aplasia hypoplasia of the lungs 0.2766254550592879 0.2095420922442438 0.8340250797712987 1.0 1.0 29 Q5H8A4,O96000,Q6NUK1,Q14739,O75844 5 +Iron deficiency anemia 0.3875338269999533 0.2087354627323621 0.8346547546225793 1.0 1.0 5 Q10471,P28288 2 +Bladder diverticulum 0.364548675652696 0.2085588607783427 0.8347926286164065 1.0 1.0 8 Q9Y4P3 1 +Anorexia 0.2859535039370821 0.2084426338689644 0.8348833702939775 1.0 1.0 23 Q14108,Q9NZ08,P04062,Q13423 4 +Microcornea 0.2776076151410748 0.2083016120051192 0.8349934730545621 1.0 1.0 27 O43505,Q96L58,Q15125,Q15555,Q8NCH0,Q15042,Q9NWM8 7 +Aplasia hypoplasia affecting the eye 0.2512683129118744 0.2075854498138425 0.8355526662577528 1.0 1.0 92 O43505,Q9UHX1,O60566,Q15645,Q08AM6,Q9BXW9,P53701,Q6NUK1,P21912,Q96I36,Q9NVI7,O43924,Q15125,O96028,Q9Y4P3,P61978,Q15555,O95721,P21964,O75569,P37268,Q7LGA3,Q02978,O95202,Q15042 25 +Esophageal carcinoma 0.5371955233706405 0.207500668344211 0.8356188707677061 1.0 1.0 2 P42224 1 +Chorea 0.2462679205233216 0.2066007796220447 0.836321651350481 1.0 1.0 85 P03886,Q9H6K4,Q99720,Q9BWD1,Q9NZJ7,P17900,P07602,Q96N66,P00846,Q5XKP0,P35637 11 +Abnormality of dental structure 0.2549472843832512 0.2062643607221282 0.8365844159438787 1.0 1.0 70 Q08AM6,Q9HC07,Q96L58,P16278,Q9Y487,Q9Y4P3,P07237,O43826,P21964,P51648,O75844 11 +Accessory spleen 0.3865298939367051 0.2054848485268924 0.8371933346552995 1.0 1.0 5 O95202,Q15904 2 +Thoracolumbar scoliosis 0.3633366303989442 0.2047942480584661 0.8377328811566622 1.0 1.0 7 P27635,P21281,O95352,P36776,Q99575,P78318 6 +Speech apraxia 0.2827547737393302 0.2030208029269646 0.8391187724130009 1.0 1.0 24 Q9Y619 1 +Broad toe 0.2799787821168163 0.2018539931295229 0.8400308698085146 1.0 1.0 25 Q9UHX1 1 +Atrial arrhythmia 0.3389467211064085 0.2002683435162556 0.8412707192128563 1.0 1.0 10 Q96RR1,P12235,P50402 3 +Absent brainstem auditory responses 0.463128630786277 0.1964229947046693 0.8442790996413359 1.0 1.0 4 O60220 1 +Orofacial dyskinesia 0.3657018509347318 0.1933405029043833 0.8466923079593105 1.0 1.0 6 Q9BPX6,Q96RL7 2 +Ectopia pupillae 0.4617914958010432 0.192902414202885 0.8470353942855469 1.0 1.0 4 O95202 1 +Protrusio acetabuli 0.5350818773267454 0.1921080379981465 0.8476575787712233 1.0 1.0 3 O75718 1 +Aplasia hypoplasia of the tongue 0.4614624505928856 0.1920398076674094 0.8477110236943548 1.0 1.0 4 P08754,Q03252,P48651 3 +Microglossia 0.4614624505928856 0.1920398076674094 0.8477110236943548 1.0 1.0 4 P08754,Q03252,P48651 3 +Open mouth 0.2749112505224943 0.1911857714717796 0.8483800507251238 1.0 1.0 28 P51812,P04350,P61978,P10644,P04062,O43909,Q10713,P42345,Q86XL3 9 +Hypoplasia of the frontal lobes 0.3370320401621652 0.1910147365715044 0.8485140476195143 1.0 1.0 10 Q86XL3,Q08AM6 2 +Abnormal cns myelination 0.2765699821556315 0.1906193560702859 0.8488238243035946 1.0 1.0 134 Q5H8A4,Q86Y39,Q99720,O00584,Q9NZJ7,P07602,O96000,P10253,Q7KZN9,Q9BTW9,P35637,Q9P0J0,Q53FT3,Q9NXE4,P51572,O00400,Q96I36,P51648,P03886,Q9Y584,P00387,Q15067,O43676,Q7LGA3,O75306,Q9NPL8,P40855,Q96CU9,Q9NR50,P49770,Q9Y5Y5 31 +Vertical supranuclear gaze palsy 0.3365369744652166 0.1886338770422838 0.850379779406411 1.0 1.0 10 Q96RR1,P61916,O15118 3 +Unsteady gait 0.2610901799110915 0.1883007761079615 0.8506408769914362 1.0 1.0 49 Q15907,Q08AM6,Q86SQ9,Q9H6K4,Q9NR50,Q10713,Q5JRX3,O75503 8 +Abnormal glomerular mesangium morphology 0.2923497226537358 0.1879300819071229 0.8509314609070557 1.0 1.0 18 O95470,Q8N1F7,Q8NFH4,Q9BW27 4 +Myopia 0.2496703194680828 0.1851753047847457 0.8530915380350779 1.0 1.0 92 Q9UHX1,Q96L58,O60220,P36543,O43819,Q53H12,P12235,Q969G3,P40939,P21912,O14936,Q8NCH0,P51648,Q9NVI7,Q9NWM8,Q8N766,O00754,Q9Y4P3,P61978,Q15067,Q15555,Q9NX14,O15460,Q9Y487,O43292,Q13045 26 +Recurrent respiratory infections 0.268458956185937 0.1840090923821543 0.8540063220302045 1.0 1.0 121 Q5H8A4,P07602,P09601,Q9NZJ7,O43909,Q9BV10,P10253,Q9BTW9,P08236,Q9H0U3,P16278,Q969G3,P04062,Q13510,Q03518,Q16637,P15586,Q9Y5U9,Q8N5M9,P04066,Q9Y4P3,Q9Y487,Q9NPL8,O95202,Q13277,Q9UJW0,Q05655,P54802 28 +Abnormality of the anus 0.2586442092018154 0.1836511741553499 0.8542871146606097 1.0 1.0 41 P53701,P16435,P16615,Q6NUK1,Q05655,P21964 6 +Inappropriate crying 0.3578032854151683 0.183000570405904 0.8547975710566156 1.0 1.0 7 Q9NZJ7 1 +Pollakisuria 0.456851119894598 0.1801078880130716 0.8570678701372132 1.0 1.0 4 O60934,Q8WVX9,Q06787 3 +Abnormality of skeletal maturation 0.2451029279558157 0.1801051786211491 0.8570699971396727 1.0 1.0 78 Q5H8A4,P51812,Q15800,Q9Y4P3,P16435,Q14108,Q9Y619,P04062,P13073 9 +Glucose intolerance 0.2547492475480108 0.1798975902968936 0.8572329670043739 1.0 1.0 100 Q86SQ9,Q86Y39,O96000,Q92620,P18031,P00846,Q06136,Q5JRA6,Q9NXE4,Q96RR1,P12235,O75844,Q9Y5U9,P03886,O76024,O60313,Q9Y4P3,Q15555,O43676,O00429,O75306,Q9NPL8,Q96CU9 23 +Arthropathy 0.3618984838497062 0.1795789351449984 0.8574831431397336 1.0 1.0 6 Q9Y3Z3,Q6DD88,O15269,P40763,O15270 5 +Inappropriate behavior 0.3008254378538919 0.1792845944191782 0.8577142427411171 1.0 1.0 15 P17900,Q9NZJ7 2 +Abnormal brainstem morphology 0.2427895488466538 0.1779544904816159 0.8587587165153336 1.0 1.0 83 O43505,Q13057,Q13409,Q96EK5,Q86Y39,O96000,Q8N183,Q10713,Q9BTW9,Q9NXE4,O43819,Q96RR1,O15121,Q969G3,Q13217,O14936,Q6ZXV5,O75251,P07942,P03886,O60313,Q9UNE7,O43676,Q9NX14,O00429,O75306,Q9NPL8,Q96CU9,O60762,Q96S52,Q9Y320,O60508,Q5KU26,Q06787,O95831 35 +Uncombable hair 0.52304147465438 0.1777670623353872 0.8589059157445376 1.0 1.0 2 Q6PGP7 1 +Eeg with focal spike waves 0.5213956550362099 0.1744938918419614 0.8614773307350432 1.0 1.0 2 P11166 1 +Generalized myoclonic atonic seizure 0.5213956550362099 0.1744938918419614 0.8614773307350432 1.0 1.0 2 P11166 1 +Genu varum 0.3328851133310024 0.1712243996929432 0.8640473226163163 1.0 1.0 10 Q9Y619 1 +Delayed ossification of carpal bones 0.5245055888107768 0.1695182870616465 0.865388989521326 1.0 1.0 3 O43909 1 +Chronic hepatic failure 0.4525788429635028 0.1693175485108453 0.8655468735470921 1.0 1.0 4 Q10713 1 +Abnormal circulating fatty acid anion concentration 0.3234960777081219 0.1686896151568359 0.8660407876210523 1.0 1.0 11 P23786,Q16836 2 +Urinary urgency 0.3540038372074711 0.1683557594636848 0.8663034100942937 1.0 1.0 7 P04062 1 +Caudate atrophy 0.5235374427218669 0.1675192979003395 0.8669614645466537 1.0 1.0 3 O60220 1 +Trichorrhexis nodosa 0.5232136977280091 0.1668534372014384 0.867485371174078 1.0 1.0 3 Q6PGP7,P18074 2 +Abnormal thalamic size 0.4515810276679858 0.1668344328802935 0.8675003248414661 1.0 1.0 4 Q9H9S5,P11166,Q9Y5P6 3 +Joint hypermobility 0.2440958032626171 0.1662060477340564 0.8679948002425568 1.0 1.0 86 Q6ZXV5,Q9UHX1,Q5H8A4,P51812,Q9Y4P3,Q01105,Q9Y619,P07237,P21964,Q9Y487,Q9NWM8,Q7LGA3 12 +Increased serum testosterone level 0.5171165240289685 0.1661640875317289 0.8680278205092231 1.0 1.0 2 P24468 1 +Bimanual synkinesia 0.5167873601053342 0.1655341362665741 0.8685235835770742 1.0 1.0 2 P19022 1 +Hepatoblastoma 0.3434510062685767 0.1654517982115841 0.8685883863296417 1.0 1.0 9 P51532,Q15477,Q969G3,Q8TAQ2,Q92785,O43826,Q6PGP7,Q96GM5 8 +J shaped sella turcica 0.4507320036758594 0.1647327077263491 0.8691543716255652 1.0 1.0 4 P08236 1 +Abnormality of the nasal bone 0.4500090685147793 0.1629511882018463 0.870556867044842 1.0 1.0 4 Q6NUK1 1 +Arteriovenous malformation 0.3727685864382871 0.1626278355211401 0.8708114691739892 1.0 1.0 5 P08236 1 +Lower limb muscle weakness 0.2564190102548958 0.1622286350250207 0.8711258109844846 1.0 1.0 41 O00400,P00846 2 +Limited elbow movement 0.2674761202794892 0.1618269819913387 0.8714421045386009 1.0 1.0 33 Q96L58,Q9H6K4,P23786,P16435,O43909,O94905,P50402,P37268,Q7LGA3 9 +Muscular hypotonia of the trunk 0.2415235702164292 0.1602908853650232 0.872651938468334 1.0 1.0 83 Q9HC21,Q86SQ9,P07602,Q9NZJ7,Q96N66,O43909,O75880,Q9BSJ2,Q9GZY8,P17900,Q96PU5,Q9BW92,Q9NVI7,Q6ZXV5,Q9Y5U9,O60313,O00754,Q86WC4,O75306,Q5XKP0 20 +Hyperkeratotic papule 0.5125082290980928 0.157485267777934 0.8748624176263449 1.0 1.0 2 Q6PD74 1 +Cutaneous cyst 0.5125082290980927 0.1574852677779334 0.8748624176263453 1.0 1.0 2 O60716 1 +Epidermoid cyst 0.5125082290980927 0.1574852677779334 0.8748624176263453 1.0 1.0 2 O60716 1 +Increased total bilirubin 0.4477671730040072 0.1574739450158568 0.8748713405510706 1.0 1.0 4 P23786 1 +Shortening of all distal phalanges of the fingers 0.3412878618236969 0.1561158239533329 0.8759417255836897 1.0 1.0 9 P16435 1 +Long eyelashes 0.2646329200908628 0.1560113762985748 0.8760240540356088 1.0 1.0 35 Q9UHX1 1 +Abnormality of the elbow 0.2579628101593739 0.1554007636789552 0.8765053821508144 1.0 1.0 53 Q9H6K4,P23786,Q9Y619,Q13510,Q7LGA3 5 +Increased circulating androgen concentration 0.5172867961804315 0.1548940103223815 0.8769048757288624 1.0 1.0 3 P24468,P04637 2 +Neonatal death 0.2965012623195415 0.154404241578625 0.8772910094702389 1.0 1.0 15 Q14739,O96000,P04062 3 +Arnold chiari malformation 0.2820525650257486 0.1527398439747396 0.8786034384547614 1.0 1.0 21 Q86SQ9,P16435 2 +Shallow orbits 0.3404057365169756 0.1523354053044772 0.8789224013829964 1.0 1.0 9 O75844 1 +Pulmonary hypoplasia 0.2753384284457976 0.1498076089499254 0.8809164060342192 1.0 1.0 24 O75844,Q6NUK1,O96000,Q14739 4 +Peripheral axonal degeneration 0.2492968767923304 0.1460527049680021 0.8838797819224407 1.0 1.0 71 Q6DKK2,Q13057,Q96BR5,Q9HC21,P07602,Q9NZJ7,P00846,Q9NRG9,Q9BTW9,Q8IV08,O95140,Q9BPX6,Q9UHD9,Q96RR1,P12235,Q96RL7,O15269,Q9NVI7,Q8TB36,P03886,O76024,O60313,P56192,Q15067,O15270,P22626,Q6PI48,O95831 28 +Knee flexion contracture 0.2697182248442525 0.1458005715384494 0.8840788247036606 1.0 1.0 26 P23786,O94905,P21912,Q86XL3,P37268,Q7LGA3 6 +Sparse lateral eyebrow 0.3478404220243967 0.1451760705539948 0.8845718586910585 1.0 1.0 7 Q92643,Q00577,Q08J23,P61978,O60828,P62140 6 +Renal hypoplasia aplasia 0.2413678845416569 0.1450420762516177 0.8846776509769412 1.0 1.0 79 Q9UHX1,O43924,P16435,Q15392,P21964,Q96I36,Q7LGA3 7 +Abnormality of the musculature of the thigh 0.3486419905240855 0.1441227169115866 0.8854035664909083 1.0 1.0 8 O14979,Q9BTV4,P50402 3 +Abnormality of the ankles 0.2593101652018978 0.1438598286913786 0.8856111577041199 1.0 1.0 38 Q9NZJ7,O75844,Q9Y4P3,O60220 4 +Abnormal ciliary body morphology 0.5042791310072435 0.1427395371305679 0.8864958903011808 1.0 1.0 2 P11047 1 +Vitreous hemorrhage 0.5042791310072434 0.1427395371305679 0.8864958903011808 1.0 1.0 2 P35222 1 +Emg neuropathic changes 0.2762743826818011 0.1406576399299178 0.8881404107464368 1.0 1.0 23 O95140,O43819,O43681,P07602,O60313,Q9NZJ7,Q96RL7,Q13510,O14773,Q16637,P22626 11 +Abnormal abdomen morphology 0.3085473336092134 0.1406038953965868 0.8881828707311903 1.0 1.0 213 Q9HC21,Q9UGP8,Q86SQ9,Q86Y39,P07602,P09601,Q9NZJ7,O96000,P23786,P54802,Q9BUB7,Q14108,Q07021,O43909,O60566,P00846,Q15392,Q10713,Q15645,Q9BT22,P10253,O43826,O75880,P08236,Q9P2J5,P61916,Q96A33,Q9H0U3,P16278,P04062,Q13510,Q96I36,Q9NVI7,P15586,O75381,P50416,P03886,P35610,P04066,P28070,O00754,P56192,Q01844,Q9Y619,P10644,O43676,P10619,Q86WC4,Q15067,P21964,P00374,Q9NZ08,P16930,Q9H9E3,Q9HC07,O75306,Q9NPL8,P40855,Q9UJS0,Q96CU9,Q96HY6,O60762,Q9UJW0,Q05655,Q14739,Q9Y5Y5,O15118 67 +Abnormality of the hallux 0.2564103987809768 0.1390038647434058 0.8894470950755835 1.0 1.0 51 Q08AM6,Q9UHX1,Q5H8A4,P04062,Q7LGA3 5 +Abnormal saccadic eye movements 0.271227074231656 0.1378590544278526 0.8903518111805204 1.0 1.0 25 O95140,O43819,O75306,Q6PI48,Q96RL7,P04062,Q10713,O14773,Q8IV08 9 +Abnormal cerebral artery morphology 0.2960194446891545 0.1374442944894024 0.8906796213010311 1.0 1.0 14 P38435,P10253,P05067 3 +Skin rash 0.2932810944928334 0.1362181667043528 0.8916488140751069 1.0 1.0 15 Q06136,P28070,Q9H4L7,Q14739 4 +High pitched voice 0.3164568887754863 0.1344453494995085 0.8930504234064962 1.0 1.0 11 O75844 1 +Telecanthus 0.257981917608566 0.1319565014876907 0.895018697586683 1.0 1.0 38 P51812,O75844,P21964,Q8NCH0 4 +Retrognathia 0.2436265427469248 0.1319237598413962 0.8950445952411332 1.0 1.0 76 Q9UHX1,Q9Y619,Q15392,Q8NCH0,O75844,Q7LGA3 6 +Abnormal sensory nerve conduction velocity 0.3477461936842566 0.1307297819702182 0.8959890719142449 1.0 1.0 6 O95140,O15269 2 +Attenuation of retinal blood vessels 0.3434193862750226 0.1290049737527731 0.8973537132324796 1.0 1.0 7 P04439,P38435 2 +Prominent eyelashes 0.3432245301681505 0.1283012240875698 0.8979105964312024 1.0 1.0 7 P51532,Q969G3,Q8TAQ2,Q92785,P20700,Q96GM5 6 +Hypoplastic fifth toenail 0.3432245301681494 0.1283012240875659 0.8979105964312055 1.0 1.0 7 P51532,Q14738,Q969G3,Q8TAQ2,Q92785,Q96GM5 6 +Genu valgum 0.2641867826616964 0.1275961397292356 0.8984685862114496 1.0 1.0 32 Q96L58,P16278,Q9Y4P3,Q9Y619,P08236,Q7LGA3 6 +Cystic hygroma 0.3422079141873664 0.1246420418015251 0.900806943364468 1.0 1.0 7 Q96S52,Q14739 2 +Abnormality of the synovia 0.2409254990483494 0.1240319863167787 0.90128994918153 1.0 1.0 78 Q08AM6,Q9UHX1,Q96A33,Q9Y584,O75844,P16435,Q9Y487,P08236 8 +Azoospermia 0.3137826473630465 0.1217441738526169 0.9031016277431632 1.0 1.0 11 P04062 1 +Abnormality of iron homeostasis 0.3584843492586575 0.1216647169121682 0.9031645574227808 1.0 1.0 5 Q6PGP7,Q15477,P28288,Q9Y276 4 +Broad femoral neck 0.4907834101382508 0.1206324358743495 0.9039821763322986 1.0 1.0 2 Q9NUQ7 1 +Abnormality of the humeroradial joint 0.3218237239165232 0.1202280998677033 0.9043024587455016 1.0 1.0 10 O43909,Q96L58,P16435 3 +Sideroblastic anemia 0.3217869092808265 0.1200629579194319 0.9044332753751324 1.0 1.0 10 Q15031,Q9BXW9,O76024,O75027 4 +Dysgraphia 0.2945518279277691 0.1179364672023435 0.9061179982194116 1.0 1.0 13 P05067 1 +Peripheral hypermyelination 0.4972011853803002 0.1176499674887094 0.9063450115088568 1.0 1.0 3 Q9NR77,P07196 2 +Limb girdle muscle atrophy 0.3039710170863011 0.1175274176043026 0.9064421184894202 1.0 1.0 12 O14979,P50402 2 +Spondyloepiphyseal dysplasia 0.4874917709019112 0.1156278279827492 0.9079475072871 1.0 1.0 2 P27635 1 +Hypoplastic fifth fingernail 0.3431114040870151 0.1155792002814331 0.9079860481832612 1.0 1.0 6 P51532,Q969G3,Q8TAQ2,Q92785,Q96GM5 5 +Abnormality of the bladder 0.2507240998913088 0.114741361255774 0.908650128872416 1.0 1.0 101 Q9UHX1,Q99720,P07602,Q9NZJ7,Q9BTW9,P35637,Q96RR1,P12235,Q969G3,P16435,P04062,Q8NCH0,P21912,Q9NWM8,O76024,Q3ZCQ8,Q9Y4P3,O94905,P21964,Q10471,Q86XL3,P22626,P51812,Q9UJS0 24 +Septo optic dysplasia 0.4855167873601074 0.1126972007596941 0.9102706205824598 1.0 1.0 2 Q8WWQ0 1 +Rotary nystagmus 0.4279149006990891 0.1121661944221968 0.9106916329242368 1.0 1.0 4 Q9NVS9,O94905 2 +Abnormality of t cell physiology 0.3115377761772615 0.1112189449202392 0.9114427289590434 1.0 1.0 11 P21964 1 +Adult onset 0.2497700761808719 0.1101955816380735 0.9122542662772748 1.0 1.0 66 P38435,Q9UGP8,Q9H0U3,Q9UHD9,P07602,O76024,Q9NZJ7,Q96RR1,P12235,Q969G3,Q07021,Q9NQZ5,P18031,P04062,O14979,P21912,Q8IV08,O15118 18 +Abnormal cranial nerve morphology 0.2526966035044757 0.1098774670976386 0.9125065529756552 1.0 1.0 59 Q9UHX1,P51812,P22626,P40855,Q96RR1,P12235,Q969G3,Q13510,P21912,P51530,Q9Y5Y5,O75381 12 +Decreased adipose tissue 0.2902769714061205 0.1065890527702496 0.91511500372905 1.0 1.0 14 O75844 1 +Delayed ability to stand 0.4895297770973651 0.1047725772790168 0.916556270421359 1.0 1.0 3 P10253 1 +Abnormal muscle fiber protein expression 0.3365059571480339 0.1045122809256249 0.9167628228822904 1.0 1.0 7 P50402 1 +Abnormality of the pulmonary veins 0.3363851346083383 0.1040930751017533 0.917095486273498 1.0 1.0 7 Q15392 1 +Cardiomegaly 0.2595019660998026 0.1040290733675911 0.9171462765268426 1.0 1.0 34 Q08AM6,P50416,P04066,P23786,Q9Y4P3,Q07021,P10644,P10253,P04062,Q14739,P54802 11 +Chorioretinal dysplasia 0.3390234820564798 0.1025785497918169 0.9182974678045626 1.0 1.0 6 O43505 1 +Multiple rows of eyelashes 0.4782751810401602 0.1024101696729553 0.9184311118830012 1.0 1.0 2 O60716 1 +Bundle branch block 0.2870107309406811 0.1016941906757795 0.9189994134101124 1.0 1.0 15 P06280,Q9HD47 2 +Abnormal neural tube morphology 0.253098897940198 0.1012562896105 0.9193470136327084 1.0 1.0 39 Q9UHX1,Q9HC21,Q9Y4P3,P21964 4 +Papilledema 0.2810341677071067 0.0990827929700316 0.9210725340734538 1.0 1.0 17 Q7LGA3 1 +Hypoplastic heart 0.4856766545933428 0.0985855315127793 0.9214673582329844 1.0 1.0 3 O60826,P24468 2 +Anterior open bite malocclusion 0.4749835418038203 0.0979699626283223 0.9219561449484108 1.0 1.0 2 P21281 1 +Aplasia hypoplasia involving the skeletal musculature 0.3270919366742296 0.097257141899424 0.9225221904012072 1.0 1.0 9 Q9Y487 1 +Elevated tissue non specific alkaline phosphatase 0.4743252139565524 0.0970994146192132 0.9226474457325252 1.0 1.0 2 Q13043 1 +Reduced vital capacity 0.4743252139565524 0.0970994146192132 0.9226474457325252 1.0 1.0 2 P06753 1 +Decreased size of nerve terminals 0.4733377221856506 0.0958044707803022 0.9236758665266496 1.0 1.0 2 P11047 1 +Tented upper lip vermilion 0.2745900465224962 0.0947533051329947 0.9245107770289084 1.0 1.0 20 Q9Y5U9,Q15907,Q4J6C6,Q9NXE4,O60762,Q13045,Q10471 7 +Congenital hypothyroidism 0.4191080002559451 0.0939446680577918 0.9251531107362276 1.0 1.0 4 Q13423 1 +Gastrointestinal stroma tumor 0.419070340266998 0.0938692640214409 0.9252130097592036 1.0 1.0 4 Q05655 1 +Cortical cataract 0.4826078536663115 0.0937918552720907 0.9252745017155446 1.0 1.0 3 Q9H6K4 1 +Goiter 0.3330879339390101 0.0927728620429107 0.9260840109607016 1.0 1.0 7 Q96RR1,P12235 2 +Symphalangism of middle phalanx of finger 0.4677419354838732 0.0887110769201658 0.9293115291371584 1.0 1.0 2 Q15233 1 +Choreoathetosis 0.2584757409616389 0.0885234491960949 0.9294606477345206 1.0 1.0 33 Q5XKP0,P00846,Q9H6K4 3 +Abnormality of the fontanelles or cranial sutures 0.2488122635200957 0.0884953772810395 0.929482958321127 1.0 1.0 101 O75718,Q96L58,O43909,Q9BT22,Q08AM6,Q16134,P16435,Q6NUK1,P07237,Q8NCH0,O75844,Q9UM00,O75381,Q15125,O00754,Q9NX62,O75431,P61978,Q9Y619,P42345,P21964,Q9Y487,Q9H9E3,P51812,P40855,P50542,Q9Y5Y5,O95831 28 +Abdominal pain 0.242036034542061 0.0871594037669236 0.9305448076081442 1.0 1.0 74 Q9NZ08,P06280,Q9UGP8,P23786,Q8NFH4,Q9Y4P3,Q14108,Q01844,P10644,P42892,P04062,Q9BW27,P21912,Q15645,Q8N1F7,Q70HW3,Q13423,P35637 18 +Abnormal posterior segment imaging 0.4152532849935684 0.0863381455415665 0.9311976159159036 1.0 1.0 4 P04439 1 +Aplasia hypoplasia of the nasal bone 0.476789776277197 0.0850283724829927 0.932238834403928 1.0 1.0 3 Q6NUK1 1 +Abnormality of humoral immunity 0.2510425000460056 0.0839735388382745 0.933077470390351 1.0 1.0 54 O60220,P09601,P28070,Q14108,Q9UJW0,Q05655,P04062,Q9BV10 8 +Delayed myelination 0.2388751307086055 0.0831833727371486 0.933705733548502 1.0 1.0 77 Q53FT3,Q15907,Q9Y584,Q96CU9,P00387,Q9BV10,Q7LGA3 7 +Abnormality of the extraocular muscles 0.4624753127057296 0.0824095251559436 0.9343210618366709 1.0 1.0 2 P43243 1 +Shoulder girdle muscle atrophy 0.4744813961145821 0.0816686569937135 0.9349102031697468 1.0 1.0 3 Q9H9S5,P06753 2 +Limb dystonia 0.2831343460673682 0.0809704308076496 0.9354654680669507 1.0 1.0 15 Q99720,P00387 2 +Cholangitis 0.4608294930875597 0.0805135933280452 0.9358287854208908 1.0 1.0 2 Q96J02 1 +Aplasia of the uterus 0.3290471480382486 0.0792193867079341 0.9368581246885996 1.0 1.0 7 Q9UNW1,O96028,O95202,Q8IY37,Q9Y5S9,P30153 6 +Abnormality of the humerus 0.286757301138603 0.0782382660312837 0.9376385234014172 1.0 1.0 13 Q9BV10 1 +Vocal cord paresis 0.4101051741803982 0.0765312112637773 0.9389964837837124 1.0 1.0 4 O95140 1 +Low back pain 0.456550362080318 0.0757449809654931 0.9396219891235508 1.0 1.0 2 Q8WVX9 1 +Narrow vertebral interpedicular distance 0.4699983818050818 0.0753330341749973 0.9399497386773444 1.0 1.0 3 Q96HY6 1 +Vertebral arch anomaly 0.4699983818050818 0.0753330341749973 0.9399497386773444 1.0 1.0 3 Q96HY6 1 +Abnormality of ocular smooth pursuit 0.271237230897646 0.0743880763134242 0.9407015962399372 1.0 1.0 20 Q6PI48,Q9BTW9,O00754,Q10713,Q9UBB4,O14773,P46977 7 +Frontal balding 0.4678959499506126 0.0724473358515784 0.9422459151729428 1.0 1.0 3 P11166,Q96CW1 2 +Symphalangism affecting the phalanges of the hand 0.4678959499506109 0.0724473358515762 0.9422459151729444 1.0 1.0 3 Q15233,P48651 2 +Proximal symphalangism 0.4678959499506109 0.0724473358515762 0.9422459151729444 1.0 1.0 3 Q15233,P48651 2 +Bone marrow foam cells 0.4667161138902064 0.0708517599039086 0.9435157368511378 1.0 1.0 3 O15118 1 +Midface retrusion 0.2368301088052221 0.0698924723725206 0.9442792446551423 1.0 1.0 78 Q9HC07,Q96A33,P51812,Q96L58,P55795,P16435,O60783,Q6NUK1,P07237,Q14739,Q9BV10,Q9BSJ2,Q9Y487 13 +Neurofibromas 0.4057698273298656 0.0685850884166829 0.9453198886344932 1.0 1.0 4 Q969G3 1 +Left ventricular noncompaction cardiomyopathy 0.4496379196840049 0.0685229334135855 0.9453693647548462 1.0 1.0 2 Q15233 1 +Cervical spinal canal stenosis 0.4636154099440127 0.0667396937736658 0.946788933678554 1.0 1.0 3 O43909,Q9NSE4 2 +Cerebellar cyst 0.2516937938714612 0.0660222012043863 0.9473601500099982 1.0 1.0 37 O43505,Q15125,P23786,Q969G3,O43175,O60566,Q15645,P15291,Q9Y487 9 +Abnormal brain lactate level by mrs 0.3091238967089298 0.0652046809831689 0.9480110341771282 1.0 1.0 10 O75306,P03886,O00429 3 +Restrictive cardiomyopathy 0.445687952600397 0.0646562301228043 0.9484477131631628 1.0 1.0 2 Q969N2 1 +Hypogonadism 0.2342449183045792 0.0643274727281759 0.9487094786775648 1.0 1.0 80 Q9Y5U9,P03886,Q4J6C6,Q86SQ9,O76024,O95470,O60313,Q96RR1,Q16740,Q92620,Q969G3,Q9Y4P3,Q15555,P10644,O95721,O00429,Q9BT22,O75844 18 +Bifid tongue 0.4613105037866234 0.0637588624625513 0.9491622345754792 1.0 1.0 3 Q6DKJ4,P61978 2 +Hip dysplasia 0.247446372581113 0.06226997731108 0.9503478366984772 1.0 1.0 45 Q15907,Q9UHX1,Q7LGA3 3 +Cerebellar hypoplasia 0.25527632122819 0.0615456252854113 0.9509246795270014 1.0 1.0 114 Q15907,Q5H8A4,O43505,Q9HC21,P55795,P23786,O60566,Q9BV10,Q10713,Q15645,Q9NXE4,Q08AM6,Q969G3,Q6NUK1,P15291,Q9Y5U9,O43924,Q8NFH4,P00374,Q9Y487,Q5XKP0 21 +Progressive inability to walk 0.2676426831408979 0.0613487677781843 0.9510814528438408 1.0 1.0 21 P00846 1 +Vitiligo 0.322605054261497 0.0583580884343 0.9534633984290152 1.0 1.0 7 P49327,Q8N766,P03886 3 +Abnormality of the dorsal column of the spinal cord 0.456700691471839 0.0579896675208082 0.9537568588014472 1.0 1.0 3 Q8WVX9,Q6PI48 2 +Spondyloepimetaphyseal dysplasia 0.323940296615198 0.0576618146291291 0.954018010573785 1.0 1.0 6 Q96HY6 1 +Communicating hydrocephalus 0.3324284373726688 0.0568574114644279 0.9546587801270336 1.0 1.0 5 P07237 1 +Congenital bilateral hip dislocation 0.4351547070441102 0.0552340476624046 0.955952004215163 1.0 1.0 2 Q9Y4R8 1 +Frontal cortical atrophy 0.2753397115135438 0.0526984153721446 0.957972201622976 1.0 1.0 16 Q7LGA3 1 +Undetectable visual evoked potentials 0.4318630678077705 0.0525452936480647 0.9580942060466746 1.0 1.0 2 Q8TC12 1 +Glomerulonephritis 0.2696586216107688 0.0519500094134686 0.9585685262939712 1.0 1.0 18 Q12769,Q8NFH4,P57740,Q05655,Q9BW27,Q8N1F7 6 +Abnormal dentin morphology 0.3300246007971624 0.051547764508524 0.9588890418418105 1.0 1.0 5 Q5JRA6,Q96L58 2 +Corticospinal tract hypoplasia 0.4302172481896008 0.0512450311275426 0.9591302693091144 1.0 1.0 2 Q13045 1 +Short philtrum 0.2476027946283427 0.0512206184162928 0.9591497222876356 1.0 1.0 57 Q9NXE4,Q5H8A4,Q08AM6,P55795,P55201,Q9BUB7,Q969G3,O96028,O75431,O95202,Q9BV10,O94905,P21964,Q10471,Q15042 15 +Optic disc hypoplasia 0.3949275362318874 0.0499617977882791 0.9601528312298526 1.0 1.0 4 Q96KP1,O14802,O95721 3 +Lumbar scoliosis 0.393610013175234 0.0478199294311813 0.9618597533357184 1.0 1.0 4 O95352,P27635,P21281 3 +Focal cortical dysplasia 0.4252797893350912 0.0475166120450777 0.9621014907924474 1.0 1.0 2 P42345 1 +Abnormality of circulating enzyme level 0.2396501152472275 0.0472871836166342 0.9622843426489038 1.0 1.0 92 O43505,Q96BR5,P23786,Q9BTV4,Q07021,P10253,P50402,P51530,Q9BTW9,Q9BPX6,Q96RR1,P12235,Q96RL7,P15291,Q9NWM8,Q6ZXV5,P50416,Q9Y584,O14653,Q9Y4P3,O14979,Q5JRX3,P22626,Q9HC07,O60762,Q16836,P42167 27 +Spinal deformities 0.3278418451400372 0.046825858544417 0.9626520194964528 1.0 1.0 5 P53007,Q8TB36,Q9Y5P6,Q9H9S5 4 +Erythrocyte inclusion bodies 0.4468225222258776 0.0464772859308718 0.9629298377196548 1.0 1.0 3 P11413,O14936 2 +Impaired tactile sensation 0.3215699208443316 0.045942827225427 0.9633558190074778 1.0 1.0 8 Q9NR77,O43776,Q6DD88,O15269,O15270,P19367,P55072 7 +Abnormality of the basal ganglia 0.2316400082231396 0.0445710217957998 0.9644492409534662 1.0 1.0 81 Q9P0J0,P03886,Q96CU9,O60220,P16278,Q9GZY8,O60313,P23786,Q96N66,P00387,P04062,O00429,P00846,Q7KZN9 14 +Abnormal urine cytology 0.248808594179746 0.0419480192850241 0.966540136209146 1.0 1.0 37 P06280,P09601,Q14108,P04062,O43826,Q9BW27,P21912,Q15645,Q8N1F7 9 +Upslanted palpebral fissure 0.2346536779590682 0.0415019864119816 0.9668957092923778 1.0 1.0 78 O75381,Q15907,Q9UHX1,Q08AM6,Q13409,P40855,O60566,Q9Y5Y5,P21964,Q86XL3,Q9BSJ2,Q9NVI7,Q9BTW9,Q7LGA3 14 +Abnormality of the intrahepatic bile duct 0.3887352548903025 0.0401220163673828 0.9679958494091028 1.0 1.0 4 Q10713 1 +Recurrent mycobacterial infections 0.4127715602370003 0.0391735938121907 0.9687519865567672 1.0 1.0 2 P42224 1 +Abnormal proportion of cd8 positive t cells 0.3166880620756066 0.0378353751100614 0.969818939295819 1.0 1.0 6 Q05655 1 +Diminished movement 0.2697228773814658 0.0366877996169947 0.9707339365904176 1.0 1.0 17 P12235 1 +Limited extraocular movements 0.3145400593471755 0.0335743381034789 0.9732165859547846 1.0 1.0 7 O43819,Q9BVA1,O75306,Q9UHD1,P11047,P51659 6 +Cerebral hypoplasia 0.2689970882725835 0.0328469458244558 0.973796641037932 1.0 1.0 17 Q08AM6,O43175,O60762,O60566,Q86XL3 5 +Shallow acetabular fossae 0.3973008558262037 0.030846555676854 0.9753919120069868 1.0 1.0 2 Q9NUQ7 1 +Right ventricular dilatation 0.3963133640553019 0.0303832527033913 0.9757614010966484 1.0 1.0 2 P19022 1 +Type i diabetes mellitus 0.2852150043932145 0.0299407204529679 0.976114330169716 1.0 1.0 12 P03886,P00403,Q13217,Q5JRA6,A5YKK6,Q96J02 6 +Abnormality of upper limb joint 0.2484533972214815 0.0299221512972859 0.9761291395770492 1.0 1.0 107 Q8IZA0,Q96L58,P23786,Q9BTV4,Q9NUQ7,Q9BUB7,O43909,Q9BV10,P50402,Q15392,P16278,Q9H6K4,P16435,Q13510,O75844,Q15125,O96028,Q9Y4P3,P42892,Q9Y619,P10644,Q15031,O94905,P37268,Q7LGA3,Q03164,O95202,O43175,Q9H4L7,P50542,O95831,Q15042 32 +Limb joint contracture 0.2430653835334275 0.0287816064822632 0.9770387707036464 1.0 1.0 99 Q8IZA0,Q9HC21,Q96L58,Q99720,P23786,Q9BUB7,O43909,P50402,Q15392,P35637,P16435,P21912,O75844,O60313,P42892,Q9Y619,O94905,Q86XL3,P37268,Q7LGA3,O60762,Q9H4L7,Q15042 23 +Anteverted ears 0.3923633969716943 0.0286062688493914 0.977178612313073 1.0 1.0 2 P27635 1 +Soft tissue sarcoma 0.2526483689255304 0.0283498762675231 0.9773831010580268 1.0 1.0 29 Q969G3,Q13126,P10644,Q05655,O60566,Q15392,P21912,Q15645 8 +Lipodystrophy 0.2509977212447091 0.0256466055499294 0.9795392124275952 1.0 1.0 32 P28070,Q9Y487,O75844,P42167 4 +Abnormal prolactin level 0.4240689715507482 0.0241737252440592 0.9807140362221688 1.0 1.0 3 Q969G3 1 +Decreased circulating antibody level 0.2419810426503501 0.0240631899181273 0.9808022050044884 1.0 1.0 42 Q9H0U3,Q9UJS0,O60220,P09601,O00754,Q9UJW0,Q05655,O43909,Q9BV10 9 +Late onset 0.2916287749779552 0.0237798175024717 0.9810282387972872 1.0 1.0 11 P18031,O76024,P43304 3 +Bulbar palsy 0.2985696181200644 0.0226466794352053 0.9819321085579368 1.0 1.0 10 O43681,P35637,P53007 3 +Onychogryposis 0.3765635286372638 0.0226269514174123 0.9819478452063032 1.0 1.0 2 P53634 1 +Lower extremity joint dislocation 0.238380858416355 0.0221154689235263 0.9823558470775128 1.0 1.0 72 Q08AM6,Q96A33,Q9UHX1,Q9Y487,P21964,O75844 6 +Abnormality of the lymphatic system 0.2644062200952273 0.0220748928934081 0.9823882141637588 1.0 1.0 134 Q15904,P07602,P54802,Q9NZJ7,Q6NUQ1,Q14108,P10253,Q10713,Q15392,Q15645,Q9BT22,P61916,P08236,Q96A33,Q9H0U3,P16278,P04062,Q13510,P15586,P04066,P28070,O00754,Q01844,P10644,Q86WC4,P10619,P16930,P21964,Q9NZ08,Q9H9E3,Q96HY6,Q9UJS0,O95202,O60762,Q05655,Q14739,O15118 37 +Increased circulating lactate dehydrogenase concentration 0.2734175949706809 0.0220565925106275 0.9824028122023328 1.0 1.0 14 P10253,Q5JRX3,P23786,Q9UJS0 4 +Abnormal stomach morphology 0.2390093518981318 0.0209996768884874 0.983245913425346 1.0 1.0 71 Q6ZXV5,Q08AM6,P51812,P21912,O76024,P40855,Q9Y4P3,P10644,Q05655,P04062,Q96PU5,O60566,Q8NCH0,Q14739,Q15645,Q9Y5Y5,O75381 17 +Colitis 0.2974201865508494 0.0181966044507252 0.9854820114448676 1.0 1.0 10 P49327,Q05655,O43826 3 +Abnormal urine carbohydrate level 0.2824257722263609 0.0178335238847307 0.9857716608156272 1.0 1.0 12 P16278,Q9UJS0,P04066,O00754,O00462,P10253 6 +Hip dislocation 0.2443069969583224 0.0172412076664058 0.9862441881037908 1.0 1.0 57 Q9Y487,Q08AM6,Q9UHX1,O75844 4 +Hyperkinetic movements 0.2900226468548016 0.017220620760871 0.9862606116395802 1.0 1.0 11 Q9NZJ7 1 +Decreased cervical spine flexion due to contractures of posterior cervical muscles 0.3086172644469417 0.0171645574701302 0.986305337063111 1.0 1.0 6 P50402 1 +Increased laxity of ankles 0.3558262014483238 0.0170988419368773 0.9863577627785782 1.0 1.0 2 O95140 1 +Stomatocytosis 0.3522053982883499 0.0163571592144755 0.9869494571667072 1.0 1.0 2 P11166 1 +Hip osteoarthritis 0.3508887425938142 0.01610186601297 0.9871531248456112 1.0 1.0 2 P51798 1 +Glossitis 0.3508887425938142 0.01610186601297 0.9871531248456112 1.0 1.0 2 O15460 1 +Gastrointestinal infarctions 0.3508887425938142 0.01610186601297 0.9871531248456112 1.0 1.0 2 O15460 1 +Anisocoria 0.3712121212121234 0.0153568027218124 0.9877475257932 1.0 1.0 4 Q9NR77,Q9NRG9,Q96ST3 3 +Autoamputation 0.3077884557932986 0.0151258911467077 0.9879317451752774 1.0 1.0 6 O15269,P48643,O15270 3 +Multiple renal cysts 0.269987087488602 0.0145185307059502 0.9884162954560812 1.0 1.0 15 P21964 1 +Abnormal circulating aromatic amino acid concentration 0.3072297117457656 0.0137603993631924 0.9890211362707828 1.0 1.0 6 P16930,Q9UJS0 2 +Elevated circulating alanine aminotransferase concentration 0.2891431099230064 0.0136618361102058 0.9890997709767682 1.0 1.0 11 O75880,Q05655,P10253,Q15904 4 +Abnormal thyroid hormone level 0.4104161621774395 0.0134137358288044 0.989297708221348 1.0 1.0 3 P16870 1 +Glomerular deposits 0.333772218564848 0.0134028329902221 0.989306406645976 1.0 1.0 2 P57740 1 +Apneic episodes precipitated by illness fatigue stress 0.3317972350230441 0.0131571345216704 0.9895024283743944 1.0 1.0 2 P53007 1 +Short sternum 0.4096984758485544 0.0128987655081462 0.9897085595268988 1.0 1.0 3 O60566 1 +Hyperactive deep tendon reflexes 0.2959634448521733 0.0126104790977895 0.9899385600929635 1.0 1.0 10 O00429,O60220 2 +Vertical nystagmus 0.3219223173140249 0.0120985958093451 0.9903469526926788 1.0 1.0 2 P50542 1 +Head banging 0.311718235681372 0.0112618256341689 0.9910145531358932 1.0 1.0 2 Q96RL7 1 +Abnormal proximal phalanx morphology of the hand 0.3059376024200947 0.0106300953554995 0.9915185707683528 1.0 1.0 6 Q08AM6,Q9BXW9 2 +Vertebral wedging 0.2975641869651113 0.0104397503660736 0.9916704356688464 1.0 1.0 2 Q96AY3 1 +Sclerosis of hand bone 0.2893350888742622 0.0101019306322668 0.9919399626009088 1.0 1.0 2 Q15125 1 +Hodgkin lymphoma 0.295120395361885 0.0094052925433796 0.9924957729266968 1.0 1.0 10 Q05655 1 +Exaggerated cupid s bow 0.305967688757004 0.0089082816793426 0.9928923135929104 1.0 1.0 7 Q96KP1,Q00839,Q969N2,P61978,P11233,Q6DKJ4 6 +Highly arched eyebrow 0.2426269577695047 0.0059901988641608 0.9952205413933042 1.0 1.0 49 O43924,Q9UHX1,P51812,Q5H8A4,Q7LGA3 5 +Reduced protein s activity 0.3975816286904696 0.0049232403110218 0.9960718384353764 1.0 1.0 3 Q9BV10 1 +Multifocal seizures 0.3975730501780036 0.0049180594276526 0.9960759721321836 1.0 1.0 3 Q10471 1 +Abnormality of lower limb epiphysis morphology 0.2659013894778895 0.0047756688388531 0.9961895820500192 1.0 1.0 16 Q96L58,Q6NUQ1,O43909,P50542,O95831,Q7LGA3 6 +Dysplasia of the femoral head 0.3956948118964323 0.0037990129418295 0.9969688335186436 1.0 1.0 3 Q96L58 1 +Progressive night blindness 0.2674430768502036 0.0023889732835396 0.9980938769139956 1.0 1.0 15 Q92620,Q10713,Q86SQ9 3 +Torsion dystonia 0.3927331710629945 0.0020955132423718 0.9983280235606108 1.0 1.0 3 P04350 1 +Joint hyperflexibility 0.2456811475545238 0.001406354516689 0.9988778918140088 1.0 1.0 35 Q9Y619,P51812,Q9Y4P3,P21964 4 +Velopharyngeal insufficiency 0.3911755021402717 0.0012290033052747 0.999019397484404 1.0 1.0 3 Q86W42,Q9BUF5 2 +Functional motor deficit 0.264516587318127 0.0004720676776495 0.9996233445023388 1.0 1.0 137 Q15907,Q9HC21,Q86SQ9,Q99720,P07602,Q9Y2R0,Q9NZJ7,P23786,Q9H2C2,Q07021,Q9H2D1,P00846,P51530,O14773,P35637,Q9GZY8,Q53H12,P53701,P12235,P04062,Q13510,Q9NWM8,P03886,O14653,Q15067 25 +Hypoplasia of the ear cartilage 0.3895291405992818 0.0003348302707967 0.9997328441014336 1.0 1.0 3 P57740,Q8WUM0 2 +Abnormal blood inorganic cation concentration 0.2462959817791385 0.0002173790094109 0.9998265566459144 1.0 1.0 34 Q4J6C6,Q9Y4P3,P05023,P10644,Q86WC4,Q9BV10,P40939,P21912,P53680,P21964 10 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fffec05c4d7e89fb796de15cd40c19582b7ff3d5 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal endothelium morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal descemet membrane morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality of von willebrand factor", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent frontal sinuses", "Absent hair", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Achilles tendon contracture", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Acute rhabdomyolysis", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior chamber synechiae", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior synechiae of the anterior chamber", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanges of the toes", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hallux", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar impression", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad long bones", "Broad metacarpals", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central opacification of the cornea", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical cord compression", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Common atrium", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased csf homovanillic acid", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased thyroid stimulating hormone level", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hypereosinophilia", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic iris stroma", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intervertebral space", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipemia retinalis", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular hyperpigmentation", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthokeratosis", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Oxycephaly", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal potassium wasting", "Renal salt wasting", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe platyspondyly", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shortening of all phalanges of the toes", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Thinning of descemet membrane", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "Truncal ataxia", "Truncal obesity", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCD3", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AKAP9", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG12", "ALG8", "ANAPC1", "ANKFY1", "ANKLE2", "ANLN", "ANXA11", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APOL2", "APP", "APPL1", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL6IP1", "ARPC1B", "ARV1", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATG7", "ATIC", "ATL3", "ATP11C", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATPAF2", "ATXN10", "ATXN2", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BRPF1", "BUB1", "BUB1B", "BUB3", "BUD23", "C19orf70", "C1QBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CAPN1", "CARS", "CASK", "CAST", "CCDC22", "CCDC47", "CCDC88A", "CCT5", "CD3EAP", "CDC40", "CDC42", "CDC45", "CDC73", "CDH2", "CDK4", "CDK5", "CDK6", "CELF2", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP4B", "CHORDC1", "CHST14", "CHUK", "CISD2", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNOT1", "CNOT3", "CNP", "COA3", "COA7", "COASY", "COG4", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ5", "COQ8A", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "CPE", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CUL3", "CUL4B", "CWF19L1", "CYB5R3", "CYC1", "DARS", "DARS2", "DAXX", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DEGS1", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJC13", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPYSL5", "DSC2", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "EPB41", "EPRS", "ERAL1", "ERAP1", "ERCC2", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC9", "EXTL3", "EZR", "FAH", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GDAP1", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPB", "GNAI2", "GNAI3", "GNS", "GOSR2", "GOT2", "GPAA1", "GPD2", "GPI", "GPKOW", "GPRASP2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HAX1", "HCCS", "HCFC1", "HELLS", "HEXA", "HEXB", "HIBCH", "HIKESHI", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFT27", "IGBP1", "IGF2BP2", "IGF2R", "IKBKB", "IMPAD1", "INF2", "INTS1", "IRF2BPL", "IRS4", "ISCU", "ITCH", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIAA0319L", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "KLC2", "KMT2A", "L2HGDH", "LAMB1", "LAMC1", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LSS", "MACF1", "MAD1L1", "MAGED2", "MAGT1", "MAN2B1", "MANBA", "MAP1B", "MAP2K1", "MAPK1", "MAPRE2", "MARS", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED25", "MESD", "MFF", "MFN2", "MGME1", "MIA3", "MIB1", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MOGS", "MORC2", "MPG", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS14", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NACC1", "NAGLU", "NANS", "NARS", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPH", "NCDN", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NEMF", "NF1", "NFS1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP56", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPM1", "NR2F2", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NT5C2", "NTHL1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "OSTM1", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDK3", "PDSS1", "PDXK", "PEPD", "PEX14", "PEX16", "PEX19", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PISD", "PITRM1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PSPH", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PURA", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRSL1", "RAB11B", "RAB18", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RALA", "RANBP2", "RANGRF", "RAPGEF2", "RARS", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RMND1", "RNASEH2A", "RNASET2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS29", "RPS6KA3", "RPS7", "RPSA", "RRP7A", "RTN4IP1", "SAMHD1", "SAR1B", "SARS", "SARS2", "SASS6", "SBDS", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SDHA", "SDHB", "SEC23A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIN3B", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC2A1", "SLC30A9", "SLC33A1", "SLC37A4", "SLTM", "SMARCA4", "SMARCAD1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMG8", "SMN1*", "SMPD4", "SNAP29", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPATA5", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SRCAP", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG2", "STAMBP", "STARD7", "STAT1", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "STX3", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL2", "TCOF1", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM22", "TIMM50", "TIMM8A", "TIMMDC1", "TJP2", "TKT", "TMCO1", "TMEM126A", "TMEM165", "TMEM199", "TMEM43", "TMEM70", "TMLHE", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOR1AIP1", "TP53", "TPI1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMU", "TSFM", "TSR2", "TTC19", "TTC37", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWNK", "UBA1", "UBA5", "UBE2T", "UBE4A", "UBE4B", "UBQLN2", "UBTF", "UFC1", "UFD1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC45A", "UNG", "UPF3B", "UQCC2", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP7", "USP9X", "VAC14", "VAMP7", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VPS13A", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS51", "VPS53", "VRK1", "WARS", "WBP11", "WDR1", "WDR36", "WDR45B", "WFS1", "WIPI2", "WNK1", "WRAP53", "XPNPEP3", "XRCC1", "YARS", "YARS2", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZPR1"], "leading_proteins": ["AAAS", "AAGAB", "ABCB7", "ABCD3", "ACAT2", "ACOX1", "ACP2", "ADA", "AGK", "AGPS", "AIFM1", "AKT2", "ALDH3A2", "ALG1", "ALG12", "ANAPC1", "ANKLE2", "AP2M1", "AP2S1", "AP3D1", "APOL2", "APP", "ARL6IP1", "ARV1", "ASAH1", "ASNA1", "ATAD3A", "ATG7", "ATL3", "ATP1A1", "ATP2A2", "ATP2C1", "ATP6", "ATP6AP1", "ATP6V0A2", "ATP6V1B2", "ATP6V1E1", "ATXN10", "B3GALT6", "B4GALT1", "B4GAT1", "BCAP31", "BCS1L", "BRPF1", "BUB1B", "C19orf70", "C1QBP", "CALM3", "CASK", "CCDC22", "CCDC47", "CCT5", "CDC40", "CDH2", "CERS1", "CHMP1A", "CHORDC1", "CHST14", "CHUK", "CLCC1", "CLCN7", "CLN5", "CLPP", "CNOT1", "CNOT3", "COA3", "COA7", "COASY", "COG4", "COLEC12", "COMT", "COX14", "COX15", "COX2", "COX4I1", "CPE", "CPOX", "CPT1A", "CPT2", "CRTAP", "CSTB", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CYB5R3", "DARS2", "DCTN4", "DDRGK1", "DEGS1", "DHCR24", "DHDDS", "DHFR", "DHPS", "DHX37", "DHX38", "DIABLO", "DNA2", "DNAJC3", "DNM1L", "DPF2", "DPM1", "DYNC1I2", "EBP", "ECE1", "EIF2B2", "EIF2B3", "EMC1", "EMD", "ERAP1", "ERCC2", "ERLIN1", "ERLIN2", "ETFDH", "EWSR1", "EXOC2", "EXOSC2", "EXTL3", "FAH", "FANCD2", "FAR1", "FASN", "FDFT1", "FDPS", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FMR1", "FOXRED1", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALNT2", "GBA", "GDAP1", "GGCX", "GLA", "GLB1", "GLUD1", "GM2A", "GMPPB", "GNAI3", "GNS", "GOSR2", "GPAA1", "GPD2", "GUSB", "GYG1", "HADH", "HADHA", "HAX1", "HCCS", "HEXA", "HIKESHI", "HK1", "HLA-A", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HS2ST1", "HSD17B4", "HTRA2", "IARS2", "IER3IP1", "IGBP1", "IMPAD1", "ITCH", "JAGN1", "KDSR", "KIAA0319L", "KIFBP", "KMT2A", "L2HGDH", "LAMB1", "LAMC1", "LARS", "LARS2", "LAS1L", "LBR", "LEMD3", "LETM1", "LMNB1", "LMNB2", "LONP1", "MAGT1", "MAN2B1", "MANBA", "MAPRE2", "MARS", "MATR3", 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0000000000000000000000000000000000000000..15fdad6ea5864673fe3ece8ab5b50dea3bb7403f --- /dev/null +++ b/msigdb_kegg/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1665752cab45f1e0a90fe2f9100c652ee5ed9cc98e255516852eab597acf387e +size 85469 diff --git a/msigdb_kegg/df_merge.tsv b/msigdb_kegg/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cee771c2ede52403de4821a2927b224ae985a378 --- /dev/null +++ b/msigdb_kegg/df_merge.tsv @@ -0,0 +1,13 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Lysosome 25 50 4.022602712995764 5.755853978173242e-05 21.740291262135923 48.609223300970875 0.8281821627988494 0.1302152537326229 7.142313942893836 4.247239237941681 3.086075071395461 0.2389623217115766 1.4141036504518665e-12 0.3807425591661329 0.0025963332517443 7.016989314219708e-07 7.196331786019585e-13 +Snare interactions in vesicular transport 13 19 3.226979871538149 0.0012510426042744 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 0.0002832454885396 0.1553991536419083 0.2872333566147377 0.0520565373494006 4.654973840468387e-07 +Parkinsons disease 14 50 3.092359676958225 0.0019857208999587 16.90776699029126 54.04126213592233 1.0315348591123816 0.3152611195514452 7.595108151251147 4.223805209268991 1.8494970521239744 0.3626807692210581 6.974211192297877e-06 9.028179583440972e-06 6.1280090098085e-06 1.114101386375826e-06 2.001607730797324e-06 +Oxidative phosphorylation 16 56 3.0000622520450637 0.0026992443315276 18.79854368932039 59.0752427184466 1.0149760730411637 0.3252836463038503 7.263801581344288 4.652138947381941 1.8018345229041028 0.3643612228552857 1.4374742525003955e-06 0.0001278661716502 6.1280090098085e-06 6.78668198438223e-06 4.3758624072794923e-07 +Sphingolipid metabolism 9 11 2.595193366967916 0.0094537715712146 5.672330097087379 11.759708737864075 0.9805985471070467 0.1821702203806468 2.452838935293596 1.3449033287601222 1.7625559835482287 0.2542774311591588 0.0002718465381502 1.0 0.2147385524083838 0.0217985290060267 0.0001380877092489 +Cardiac muscle contraction 6 17 2.560035658689071 0.0104661423637792 7.728155339805825 19.856796116504853 1.0644813600437804 0.240240383706381 3.4195161605095614 1.765741250102918 1.6465694074711887 0.3002212677564749 0.0267348588950776 0.0012844156650938 0.0091243340822671 0.0230341265569123 0.0660317196551079 +Glycosaminoglycan degradation 4 6 2.4740347683011223 0.0133596694591642 3.407766990291262 5.864077669902913 0.1350713234786387 0.1703873780123549 1.3379225542760151 0.7043353086258667 1.932540087143412 0.2532951180616937 4.815836726362641e-05 1.0 1.0 0.0328731354880699 0.0001590313802548 +Calcium signaling pathway 7 15 2.4384806452369 0.0147491484980351 5.735436893203883 16.946601941747574 1.0005800740695592 0.3113014190776675 2.984654368989517 2.3866666657890168 1.2450167285670062 0.3187454651207294 0.0111149711045206 0.2695684389372801 0.0244837275894334 0.0047615333276254 0.0130614889048102 +Huntingtons disease 15 73 2.3319405950000025 0.0197038165031342 19.631067961165048 76.91504854368932 0.635715043905642 0.4301008974270168 9.08454389027927 5.4148363920790175 1.5734816663041495 0.3870978376334237 0.0005123478945053 7.334818516053075e-05 8.933524180276066e-05 0.0002634217628024 0.0003211646817477 +Alzheimers disease 12 54 2.2747856854477138 0.0229187893566753 16.135922330097088 58.91990291262136 0.6161331149111849 0.4362889390372475 6.737157569069632 4.882193919366804 1.448905264905826 0.3805753751040122 0.0014583266869286 0.000407082511055 0.0002703653485467 0.0047477953437223 0.0018494688842427 +Glycerophospholipid metabolism 13 18 2.2675749305111808 0.0233551271034364 5.553398058252427 16.104368932038835 0.8448777148315795 0.3373638196000335 3.045697762577092 2.514285464673758 1.2272389207362138 0.3056726473181033 0.611913865163416 1.0 1.0 0.7349303615645701 0.2675058784158126 +Other glycan degradation 6 8 2.0502379862188658 0.0403412128197646 3.966019417475728 7.12378640776699 0.0449593300314452 0.158186848086018 1.7909726921672984 0.8075596903062239 1.9584092358200416 0.2320333335657103 0.0143571981203825 1.0 1.0 0.0439142352380576 0.0278921605814954 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6009a65e8f010079e3a2213904ce22d72214b89e --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 180, + "title": "Average number of proteins per term", + "value": 15.833333333333334 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6e210bb3326c7a9f0259dcfd113a3904dd4fdf8d --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..963b3a3332236070dd65002792b204783e208605 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,65 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Lysosome 0.6434843696955218 4.022602712995764 5.755853978173242e-05 0.0103073467744969 0.010360537160712 50 P11279,P54802,P07602,Q9NZJ7,Q14108,P10253,P50897,O14773,P61916,P08236,P11117,P06280,P16278,P17900,P04062,Q13510,P15586,O75503,Q93050,P10619,Q9Y487,Q9UMR5,Q9Y2T2,P06865,O15118 25 +Snare interactions in vesicular transport 0.7196003946476539 3.226979871538149 0.0012510426042744 0.2017461673189616 0.0369599291367522 19 Q86Y82,P56962,Q13190,O14653,O43752,Q9P2W9,Q13277,O75396,Q9UEU0,Q12981,O15155,O95249,O15400 13 +Parkinsons disease 0.5376184665706402 3.092359676958225 0.0019857208999587 0.3007766852901157 0.0446787202490717 50 P03886,O14949,P24539,O96000,P12235,P45880,Q9Y277,P12236,O43676,P14406,Q9UDW1,P00846,P21796,P13073 14 +Oxidative phosphorylation 0.5164557674420174 3.0000622520450633 0.0026992443315276 0.3852385022037602 0.0539848866305536 56 P03886,O14949,Q86Y39,P24539,O96000,O75438,O75964,Q93050,P14406,Q9UDW1,O43676,Q7KZN9,P00846,P56385,P13073,Q9Y487 16 +Sphingolipid metabolism 0.740915638519806 2.595193366967916 0.0094537715712146 0.8190932514563778 0.0945377157121463 11 Q9NXE4,O43681,P06280,P16278,O95470,O15269,P04062,Q13510,Q06136 9 +Cardiac muscle contraction 0.634900425292914 2.560035658689071 0.0104661423637792 0.8495062268391258 0.095569144760925 17 O14949,P05023,P16615,P14406,Q9UDW1,P13073 6 +Glycosaminoglycan degradation 0.8489407776348025 2.4740347683011223 0.0133596694591642 0.9111626658217256 0.104553934897807 6 P08236,P15586,P16278,P06865 4 +Calcium signaling pathway 0.6380253470805921 2.4384806452368997 0.0147491484980351 0.9310669653802836 0.1106186137352632 15 P0DP25,P12235,P45880,Q9Y277,P12236,P16615,P21796 7 +Huntingtons disease 0.4159942575545712 2.3319405950000025 0.0197038165031342 0.9721826258984454 0.1340958079853009 73 O14949,P24539,O96000,P12235,O75438,P45880,Q9Y277,P12236,O43676,P14406,Q9UDW1,Q9UJW0,P00846,P21796,P13073 15 +Alzheimers disease 0.4478251129928288 2.2747856854477138 0.0229187893566753 0.9846000563414936 0.1449628578833987 54 O14949,P0DP25,P24539,O96000,O75438,P16615,O43676,P14406,Q9UDW1,P00846,P13073,P05067 12 +Glycerophospholipid metabolism 0.5792794480401898 2.2675749305111808 0.0233551271034364 0.9857897601652033 0.1449628578833987 18 Q6P1A2,Q86UL3,Q8NCC3,Q96N66,O14735,O95674,Q7L5N7,Q9UG56,Q92604,Q99943,Q9HBU6,Q8NF37,P43304 13 +Other glycan degradation 0.729671019822988 2.0502379862188658 0.0403412128197646 0.9993960069035368 0.2074690945016468 8 P16278,P04066,O00754,P04062,P06865,Q9BTY2 6 +N glycan biosynthesis 0.5409353092047299 1.8709212422961004 0.0613559982008649 0.9999887755863904 0.2568390622361786 16 Q86YN1,P04844,Q9BT22,Q9BV10,P15291,P46977 6 +Glycosphingolipid biosynthesis ganglio series 0.8707097995552271 1.775673127231588 0.0757868091388527 0.9999993097772216 0.2902473541487976 4 O00400,P06865 2 +Riboflavin metabolism 0.7291769388882314 1.711333937180603 0.0870194848862715 0.9999999236038276 0.3012212938370938 5 Q9NPH0 1 +Renin angiotensin system 0.8322000047025073 1.6169220182463089 0.1058951149333999 0.999999998222031 0.3529081952253008 4 P10619 1 +Protein export 0.5027176717787462 1.6080096758748814 0.1078330596521752 0.9999999987968972 0.3529081952253008 16 Q9Y5M8,Q9UGP8,Q99442,P67812,Q9UHB9,Q15070 6 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.6591957811469842 1.5842713351296625 0.1131319859858119 0.9999999995882642 0.3572589031130905 6 Q92643,Q5H8A4,Q9H490,Q96S52,O43292 5 +Steroid hormone biosynthesis 0.8933508887425811 1.519970599727537 0.1285183649520989 0.9999999999823608 0.3920899269725051 2 P21964 1 +Nicotinate and nicotinamide metabolism 0.6745687934355626 1.4600080855374622 0.1442878517717511 0.9999999999993407 0.4173175261701524 5 Q13423,Q9BQG2 2 +Metabolism of xenobiotics by cytochrome p450 0.6105184753262343 1.4505517634748042 0.1469047153735594 0.9999999999996202 0.4173175261701524 8 O43708,P78417,P07099 3 +Ecm receptor interaction 0.6214247678951004 1.397822893585667 0.1621662577611542 0.9999999999999852 0.4191356681473912 6 Q08722 1 +Progesterone mediated oocyte maturation 0.4318835737873363 1.382003529355286 0.1669706174294314 0.9999999999999948 0.4191356681473912 23 Q9UJX3,Q99640,P51812,Q9UJX2 4 +Vibrio cholerae infection 0.4448789590558726 1.368922155783233 0.1710236093111221 0.9999999999999978 0.4217020503561915 20 O43731,Q9Y487,P24390 3 +Porphyrin and chlorophyll metabolism 0.4793526559274175 1.346866216124534 0.1780233239282254 0.9999999999999996 0.4330297068524402 14 P09601,P30519,Q7KZN9,P08236 4 +Steroid biosynthesis 0.5117008517912054 1.2796397052749564 0.2006718789324928 1.0 0.4752755027348514 11 Q16850,Q14534,P35610,Q15800,Q15392,P37268 6 +Glycosaminoglycan biosynthesis chondroitin sulfate 0.8445834705301193 1.2384659881855438 0.2155433258558035 1.0 0.4963501969286764 3 Q96L58,Q8NCH0 2 +Glycosphingolipid biosynthesis globo series 0.842437504029815 1.230064643469864 0.2186728987195221 1.0 0.4963501969286764 3 P06865 1 +Phosphatidylinositol signaling system 0.4653192730608348 1.2104269919936437 0.2261150897119526 1.0 0.4963501969286764 13 P0DP25,Q8NEB9 2 +Glycosaminoglycan biosynthesis keratan sulfate 0.8127057274522719 1.1780464104396002 0.238778104508796 1.0 0.5056477507245092 2 O43505 1 +Glycosphingolipid biosynthesis lacto and neolacto series 0.8127057274522719 1.1780464104396002 0.238778104508796 1.0 0.5056477507245092 2 O43505 1 +Glycosaminoglycan biosynthesis heparan sulfate 0.8254856766545837 1.1637981496498957 0.2445058221988367 1.0 0.5117563720440769 3 Q96L58,Q7LGA3 2 +Drug metabolism cytochrome p450 0.5540429782694694 1.1327096879852043 0.2573361879165272 1.0 0.5301444118846368 7 O43708,P78417 2 +Alpha linolenic acid metabolism 0.803753704313461 1.0792070766813513 0.2804954256733796 1.0 0.5632715654707523 3 Q15067,O15254 2 +O glycan biosynthesis 0.8030951596970617 1.076651957787676 0.2816357827353761 1.0 0.5632715654707523 3 Q10472,O43505 2 +Cell adhesion molecules cams 0.5261557372383243 0.9881580010595576 0.3230752734605526 1.0 0.6121426233989419 7 P04439,Q92896 2 +Biosynthesis of unsaturated fatty acids 0.474660456155217 0.9603729653954826 0.3368675392759672 1.0 0.6264336869271667 10 Q9NZ01,O15254,Q53GQ0,Q15067,O95864 5 +Regulation of autophagy 0.5165842450470391 0.873894474210331 0.3821757242494554 1.0 0.6753681939198026 6 O95352,Q8NEB9,Q6PHR2 3 +Tyrosine metabolism 0.4801521461832956 0.8703215796434094 0.3841246890985652 1.0 0.6753681939198026 9 O43708,P21964 2 +Proximal tubule bicarbonate reclamation 0.5107566529059191 0.8449731130676089 0.3981258510134045 1.0 0.6760627658718189 6 P05023,P54709,Q9UBX3 3 +Terpenoid backbone biosynthesis 0.4623950235525707 0.7719162697473846 0.4401640204798092 1.0 0.7353307966985797 9 P14324,Q5T2R2,Q86SQ9,Q9BWD1 4 +Mtor signaling pathway 0.3999912835328545 0.7701709762913761 0.4411984780191478 1.0 0.7353307966985797 13 P51812,Q6PHR2,Q15418,Q15382,P42345 5 +Dilated cardiomyopathy 0.4622606457810119 0.6086658235939325 0.5427459646628368 1.0 0.8206771920006497 6 P16615 1 +Peroxisome 0.311674398268301 0.5291849898994053 0.5966771281772965 1.0 0.8766555705056709 31 O75381,O15254,Q9BQG2,O14734,P40855,O00116,Q9UKU0,Q15067,O75192,Q9Y5Y5,P28288,O43808 12 +Autoimmune thyroid disease 0.5455279589569217 0.4545397238265061 0.6494404074034139 1.0 0.9132755729110508 4 P10321,P04439 2 +Allograft rejection 0.5455279589569217 0.4545397238265061 0.6494404074034139 1.0 0.9132755729110508 4 P10321,P04439 2 +Graft versus host disease 0.5455279589569217 0.4545397238265061 0.6494404074034139 1.0 0.9132755729110508 4 P10321,P04439 2 +Gnrh signaling pathway 0.3938101687183487 0.4047946946831163 0.6856284288387691 1.0 0.9279181743682589 9 P0DP25 1 +Aldosterone regulated sodium reabsorption 0.4039998826629419 0.3795531384781816 0.7042771520802451 1.0 0.9390362027736602 7 P05023,P54709,Q96PU5 3 +Hypertrophic cardiomyopathy hcm 0.3835517279482042 0.2910195105100612 0.771036397775906 1.0 0.9637954972198826 8 P16615 1 +Folate biosynthesis 0.4936615324888092 0.2831643619960952 0.7770508457890086 1.0 0.9646148430484244 4 P00374 1 +Type i diabetes mellitus 0.3802709557150381 0.2483535153149458 0.8038608964154614 1.0 0.9875443246884064 6 P10321,P04439,P16870 3 +Galactose metabolism 0.3148615734665705 0.2449507935633573 0.8064945318288652 1.0 0.9875443246884064 14 P52789,P10253,P06280,P16278 4 +Antigen processing and presentation 0.3037058707215579 0.2148536209861091 0.8298814454751176 1.0 1.0 16 Q99538,P27824,P04439,P61289,Q03518 5 +Arachidonic acid metabolism 0.4602084167669046 0.1887659171975495 0.8502762856895762 1.0 1.0 4 P09960 1 +Oocyte meiosis 0.2598720343718275 0.162859194429138 0.8706292999352139 1.0 1.0 39 P0DP25,Q99640,Q9UJX2 3 +Ppar signaling pathway 0.2865989642925545 0.1314156428682195 0.8954465147592507 1.0 1.0 17 P50416,O15254,P23786,Q9UKU0,Q15067 5 +Type ii diabetes mellitus 0.3192120889790984 0.1085917726044067 0.9135262866730512 1.0 1.0 10 Q05655 1 +Inositol phosphate metabolism 0.2836064221324788 0.0720156236373396 0.9425894742703806 1.0 1.0 14 Q8NEB9 1 +Vascular smooth muscle contraction 0.2788369186599462 0.0481842429191468 0.9615694079297314 1.0 1.0 14 P0DP25 1 +Prostate cancer 0.2704132231404917 0.0165743023305269 0.9867762255121656 1.0 1.0 15 O15111,P04637,P62993,P35222,P31751,P28482,P49841,O14920,P42345,P07900,P08238,P24941,P27361,P14625 14 +Long term potentiation 0.2730224952536472 0.0130300103433839 0.9896038500991596 1.0 1.0 13 P0DP25 1 +Vasopressin regulated water reabsorption 0.269199520092954 0.0107371727619529 0.991433140234635 1.0 1.0 15 Q15907,Q9UJW0 2 +Hedgehog signaling pathway 0.3974316759960483 0.0048327701952713 0.996144022285113 1.0 1.0 3 P48729,P49841 2 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0f9d77ee4b542c2084942578a72d8ce5267a7d91 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taurine and hypotaurine metabolism", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG8", "ALYREF", "ANAPC1", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "APP", "APPL1", "APRT", "AQR", "ARF6", "ARFGAP1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASNA1", "ASNS", "ATG7", "ATIC", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BAIAP2", "BCAS2", "BDH2", "BET1", "BIRC6", "BLM", "BLVRA", "BNIP1", "BPNT1", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2D", "CAMK2G", "CANX", "CAPN1", "CAPN2", "CARS", "CASK", "CBR1", "CCDC6", "CCNB1", "CCNB2", "CD47", "CDC23", "CDC27", "CDC34", "CDC40", "CDC42", "CDC45", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDS2", "CETN2", "CFL1", "CFL2", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CHMP4B", "CHMP5", "CHORDC1", "CHST12", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "COASY", "COMT", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPE", "CPOX", "CPT1A", "CPT2", "CRKL", "CRNKL1", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CWC15", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBT", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DEGS1", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH3", "DIS3", "DLAT", "DLD", "DLST", "DNA2", "DNM1L", "DNM2", "DNMT1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSC2", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "EMD", "ENAH", "ENDOD1", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERCC2", "ERO1A", "ETNK1", "EXO1", "EXOC4", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAH", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GBE1", "GCAT", "GCDH", "GCLM", "GFPT1", "GGA2", "GGCT", "GGH", "GGT7", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMPPB", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNPDA1", "GNPNAT1", "GNS", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPI", "GRB2", "GRHPR", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADH", "HADHA", "HADHB", "HCCS", "HDAC1", "HDAC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGF2BP1", "IGF2R", "IKBKB", "ILK", "IMPDH2", "INPP4A", "IQGAP1", "IQGAP2", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "JUP", "KARS", "KDELR1", "KDELR3", "KDSR", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAP3", "LARS", "LARS2", "LDHA", "LDHB", "LGMN", "LIG1", "LIG3", "LIPA", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LSM2", "LSM3", "LSM4", "LSM7", "LSS", "LTA4H", "LYPLA1", "M6PR", "MAD1L1", "MAN1A2", "MAN2B1", "MANBA", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPG", "MPHOSPH6", "MPI", "MPST", "MRE11", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTR", "MUT", "MYH10", "MYH14", "MYH9", "MYL6", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCBP1", "NCBP2", "NCK2", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEFM", "NF1", "NFKBIE", "NLN", "NME1", "NME2", "NNT", "NOTCH2", "NPC1", "NPC2", "NSD2", "NSDHL", "NSF", "NT5C2", "NTHL1", "NUDT12", "NUDT5", "NUDT9", "OAT", "OCRL", "OGDH", "ORC3", "OXA1L", "OXCT1", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PATL1", "PC", "PCBP1", "PCCA", "PCCB", "PCNA", "PDCD6", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDSS1", "PECR", "PEX11A", "PEX14", "PEX16", "PEX19", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHF5A", "PHGDH", "PI4KA", "PI4KB", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3C3", "PIK3R4", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PLA2G15", "PLCG1", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "PPA1", "PPA2", "PPAT", "PPID", "PPIH", "PPIL1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSPH", "PTDSS1", "PTGES2", "PTPN1", "PTPN11", "PUF60", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "RAB11B", "RAB13", "RAB23", "RAB5A", "RAB5B", "RAB5C", "RABEP1", "RAC1", "RAD21", "RAD23B", "RAD50", "RALA", "RAPGEF2", "RARS", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RDH11", "RDX", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RNASEH2A", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RUFY1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEPHS1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC33A1", "SLIT2", "SLK", "SLTM", "SMAP1", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SNAP23", "SNAP29", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORD", "SORT1", "SPCS2", "SPCS3", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SV2A", "SYMPK", "TAB1", "TAF6L", "TALDO1", "TAP1", "TARS", "TARS2", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMLHE", "TOLLIP", "TOMM40", "TP53", "TPI1", "TPM3", "TPM4", "TPP1", "TPR", "TRA2A", "TRA2B", "TRIM21", "TRIM25", "TRIP12", "TRMT11", "TROVE2", "TSG101", "TSTA3", "TTC37", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNRD1", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBR5", "UCK2", "UGDH", "UGP2", "ULK3", "UMPS", "UNC45A", "UNG", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USP39", "UXS1", "VAMP7", "VAPA", "VARS1", "VARS2", "VASP", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS25", "VPS37B", "VPS45", "VPS4B", "VTA1", "VTI1B", "WARS", "WBP11", "WDR61", "XAB2", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YES1", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZYX"], "leading_proteins": ["ABCD3", "ACAT2", "ACOT8", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL6", "AGPAT1", "AGPS", "AKT2", "ALG1", "ALG12", "ANAPC7", "AP3M1", "APP", "ASAH1", "ASNA1", "ATG7", "ATP1A1", "ATP1B3", "ATP2A2", "ATP5F1", "ATP5I", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V0A2", "B3GALT6", "B4GALT1", "B4GAT1", "BET1", "BNIP1", "CALM3", "CANX", "CD47", "CDC23", "CDIPT", 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biosynthesis 20 32 2.8909969835905365 0.0038402180625167 9.439320388349516 29.58009708737864 1.1800609247564997 0.3081196451067344 4.809346434845489 4.094857299253986 1.3402414818469337 0.3224557628717913 0.0440186989799697 1.0 0.5657328567415809 0.0178492752405101 0.002896721501077 +Mitophagy 3 12 2.713510812344712 0.0066574395630336 3.662621359223301 11.783980582524272 1.3564301304992197 0.1917930287367771 1.8155907654273165 1.3363606860118669 1.2723890100166135 0.2636913304405313 0.0117835559510333 0.0001966568602221 7.357256485958134e-05 0.0024379570615939 0.0052582215982291 +Cristae formation 14 21 2.6967673826648904 0.0070016161557771 8.475728155339805 19.805825242718445 0.8613288847471563 0.2756396593916832 3.7825471979528897 1.2052333490949263 1.5890526548766304 0.3070386069824295 4.626777593685669e-06 0.0073558029266518 5.053603155069604e-06 3.671693537728937e-05 2.7061211228180336e-07 +Gpcr ligand binding 6 10 2.6508693835595944 0.0080284883118602 3.4611650485436893 9.330097087378642 1.051447004644797 0.2131328881138611 1.5951828582954857 1.3192992367203638 1.3003237502897853 0.2397874119507845 0.0290968026183098 1.0 1.0 0.0998367022916053 0.0063580922287898 +Respiratory electron transport 17 51 2.553722813120892 0.0106578063840245 17.473300970873787 52.5752427184466 0.7619430018929745 0.3962973483509951 7.757662405441163 5.39117119769307 1.7039672197087123 0.3858226471737118 0.0014815340416486 0.0846554635732882 0.0731929968318565 0.0030790050493254 2.671732266324261e-05 +Cargo concentration in the er 10 15 2.5475221908173498 0.0108490952802735 4.813106796116505 14.480582524271844 0.5034715777808771 0.4707340910089172 2.4168749497181627 1.7521447745979526 1.0073939692365603 0.3173017432503084 0.2157874462253757 1.0 1.0 0.4314443861210575 0.0986013223955862 +Pink1 prkn mediated mitophagy 3 9 2.5385757118456507 0.0111304716643836 3.2815533980582523 8.473300970873787 1.395617281862234 0.1554977461962819 1.6230588150315317 0.9738153254376878 1.3577427922485954 0.2414588001366878 0.0032517223418875 6.765318543664244e-05 1.7352123755419733e-05 0.00062382482254 0.0010145405611514 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 7 17 2.519969030512148 0.0117365159999276 6.014563106796117 17.274271844660195 0.870961683103299 0.329566970411291 2.8591161566949044 2.4465188670593117 1.2657234914365352 0.3108311955329007 0.0186463268964918 1.0 1.0 0.3949435131867426 0.0535493385180635 +Peptide ligand binding receptors 5 7 2.4763332886398306 0.0132739600464932 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.0003215953133908 1.0 1.0 0.0074273483269255 0.0001004910149917 +Class a 1 rhodopsin like receptors 5 7 2.4763332886398306 0.0132739600464932 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.0009332110294809 1.0 1.0 0.0135296171343662 0.0003730251283681 +G alpha q signalling events 6 12 2.464465810761928 0.0137217653781507 2.8567961165048543 12.349514563106796 -1.2201103518730343 0.2572818502952295 1.7477801252441654 2.6253385833016627 1.1290382202140006 0.2921395940828384 0.1040729771140581 1.0 1.0 0.0756483536674149 0.1007899732540167 +Transport of vitamins nucleosides and related molecules 5 8 2.4248969630231305 0.0153127321164583 3.2985436893203883 7.703883495145631 0.5884630304197642 0.3368828823659784 1.766928610360549 0.9135891377639136 1.2550983698791685 0.3076045725047946 0.0009332110294809 1.0 0.1837383274168749 0.0135296171343662 0.0003730251283681 +Ras processing 2 5 2.381088606489777 0.0172615593809171 1.3519417475728157 4.871359223300971 1.1011688928930974 0.2799307194914149 1.0191949595335985 0.8620674500492106 1.0561018280407846 0.2880746444526379 0.033250781651387 0.0036723611473879 0.014058804472369 0.0102137155300364 0.0621142898948071 +Heparan sulfate heparin hs gag metabolism 4 5 2.3477147156485585 0.0188889826319451 2.4320388349514563 4.83252427184466 0.8003221575390526 0.2230961855611341 1.2648123228701085 1.2708877857521428 1.4628061886044337 0.2633127679646707 0.0314966989465631 1.0 0.266209970857853 0.544318157098314 0.0181161163925661 +Organelle biogenesis and maintenance 30 91 2.333028247364234 0.019646662814174 25.364077669902912 93.59466019417476 0.8635708484684039 0.4952956395971041 8.486338013959335 9.495950625534562 1.0729913690397648 0.3929655478972317 0.0482094517874212 0.1375128720141114 0.0145543964999889 0.061473738921183 0.0211261399454728 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 6 10 2.293293352856806 0.0218311216692557 4.016990291262136 10.99757281553398 1.1239772251284714 0.2752182956921286 1.9514004604865949 1.181365809872934 1.0815649178051203 0.2865915409883788 0.0049881070407295 0.0875404472016038 0.014058804472369 0.0102137155300364 0.0119688845689888 +Processing of smdt1 6 11 2.2914056044160565 0.021939965739492 4.975728155339806 11.155339805825244 0.3833102568885913 0.3649000478471426 2.609615007852169 1.2287595888742628 1.3301610577177632 0.3259664414506655 0.0208873878301334 0.0742352733278267 0.1432798584585485 0.3247468214281712 0.039942155971048 +Cholesterol biosynthesis 8 16 2.2600633181355767 0.0238173213500738 5.878640776699029 16.75 1.3996798653689082 0.2350718901934974 2.503362805703168 1.8986773628384943 1.0886216368414 0.270950573691616 0.0002133439289579 1.0 1.0 0.0002335266734922 9.63883996768495e-07 +Ion channel transport 14 28 2.259737456407572 0.0238375501419403 9.031553398058252 27.74271844660194 0.8980727715308076 0.3472480807052641 4.2752930421976005 3.4432740668393595 1.4212023690700646 0.3452897078102002 0.0353363024410876 0.3274019772455256 0.0442161560616649 0.0143895951598155 0.1034454751370625 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 3 5 2.2463367763006965 0.0246824446369713 2.2694174757281553 4.735436893203883 0.3669027527063505 0.3957232167693734 1.21588860409113 0.4465689624800877 1.1543527848059545 0.3128036344848447 0.0026155774748029 1.0 1.0 0.0148625463558957 0.0003311660608568 +Diseases of glycosylation 8 20 2.224868228288659 0.0260900854593075 6.359223300970874 19.17718446601942 0.13180823173309 0.3045208720095976 2.4657040544471793 2.991113672999948 1.5111068586159069 0.284004628008759 0.0078211428087944 1.0 0.1656331484196294 0.0101205340460747 0.0111310072807516 +Ire1alpha activates chaperones 9 26 2.189878583063273 0.0285330436022241 6.050970873786408 24.223300970873787 0.9379365742980283 0.4047880585679882 2.6930013625985207 2.1985522104416564 1.0262193137091864 0.3353529084578252 0.0012042412797456 0.1913705796369965 0.3467918934582977 0.0213813720021448 0.0011157102419642 +Keratan sulfate keratin metabolism 4 6 2.182736355616873 0.0290552309776401 3.1359223300970873 5.439320388349515 0.1148000450757159 0.1857420338858874 1.294488268568909 0.7592200419566036 1.8452752770630356 0.2520366769461069 0.0032517223418875 1.0 1.0 0.062605312422627 0.0079370796506279 +Sphingolipid de novo biosynthesis 4 11 2.1710033181828026 0.0299309215522209 4.08252427184466 10.614077669902912 1.3205451179619188 0.2079933246203462 1.939118365602947 1.3614298144224892 1.289169434780902 0.261809046515659 0.0227199243381966 1.0 0.2445730022705269 0.0322769586697076 0.012033886898071 +Class i peroxisomal membrane protein import 7 9 2.128375740629424 0.0333059428704671 4.300970873786408 9.604368932038836 1.1426576411245968 0.2560233101944223 2.515331441636984 1.9424437465598188 1.2133199793435778 0.2911424942178205 0.033250781651387 1.0 0.1677870330809631 0.0762921742488627 0.0119688845689888 +Mitochondrial biogenesis 18 33 2.1168784226858945 0.0342701673750802 10.572815533980584 33.521844660194176 0.7125383902440768 0.3998427377933914 4.798567629623383 2.9315837025395943 1.2191838320541302 0.3355715376706868 0.0149053783797515 0.0627750690965546 0.00132313066272 0.0169357854376417 0.0080072027585734 +Chondroitin sulfate dermatan sulfate metabolism 3 5 2.093792739116455 0.0362784472612562 1.7936893203883495 4.021844660194175 0.1833102203803382 0.2980238462552717 1.0674618205957698 1.1286251173357766 1.5088456365203304 0.2864106402914596 0.3430575480785555 1.0 0.266209970857853 0.181169408752189 0.0678374957909117 +The citric acid tca cycle and respiratory electron transport 23 94 2.0276211446931653 0.0425989292613702 27.99757281553398 94.17961165048544 0.4883573568636233 0.4259472248586306 12.60942373482268 7.020896123249261 1.7895370613076145 0.38969273744301 3.3841933733637085e-05 0.0071507315102851 0.0008601038878761 0.0001342725420134 7.593120765025815e-07 +Intra golgi traffic 7 14 2.0049836459361288 0.0449647954151282 4.424757281553398 13.87135922330097 0.7636302424906817 0.4243971711811651 2.688824171738392 3.845367291797066 0.9598354803720488 0.3140361333882177 0.0203969030796003 1.0 1.0 0.2707185745648809 0.0152089373127818 +Phase i functionalization of compounds 4 12 2.0012173837354794 0.0453689683817017 3.5364077669902914 14.184466019417476 1.0829555250605305 0.2802752482018614 1.63283502003666 1.0657744603346575 1.0337417132355466 0.2758879448139676 0.0151318124703484 0.1715759324473242 0.3143397790261298 0.0142235096743441 0.0393164024746651 +Iron uptake and transport 3 18 1.9661702798114011 0.0492789443154237 4.089805825242719 17.9126213592233 1.0360420001787272 0.323786301352462 2.0477771422769826 0.9863810102632052 1.0014322629164618 0.2971986354372174 0.0542703985223047 0.0142466262053111 0.005693097574516 0.0130060888805635 0.1114244714574529 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..33992c2a379d0499eb61ad0bc549ab3ce1b62118 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 1382, + "title": "Average number of proteins per term", + "value": 18.958031837916064 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..cc7c0703c1cdb32730647a96dd0c3c90a715b61b --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f84412bd4d1ff5f93058d52b4eace7af738f698e --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,331 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein localization 0.5843486957731245 4.088054930303349 4.350051636903274e-05 0.0583475497240153 0.0404386568118239 71 Q9NS69,O14734,Q8N4H5,Q99595,P09601,O60220,O60830,P12236,Q10713,P50402,Q96B49,P28288,O43808,Q9HAV7,O15254,P62072,P46379,P12235,O43615,Q15388,O14925,Q9Y512,P51648,O75381,Q13190,O43681,Q9Y584,Q3ZCQ8,P06576,Q15067,P21796,Q5JRX3,Q13505,P40855,Q9UJS0,O96008,Q9Y5J9,Q9Y5Y5,Q9NX63,P05067 40 +Mitochondrial protein import 0.6586374064415684 3.750959124237894 0.0001761594192661 0.2160999571727619 0.0404386568118239 37 Q13505,Q9NS69,Q8N4H5,O60220,Q99595,Q9Y584,P62072,P12235,O60830,Q9Y5J9,P12236,P21796,O14925,Q5JRX3,Q96B49 15 +Sphingolipid metabolism 0.7338449561819846 3.7129877917078007 0.0002048267711163 0.2465552528409338 0.0404386568118239 25 P06280,Q96G23,P07602,O95470,Q9NZJ7,P17900,P04062,P10619,Q13510,P06865,Q06136,P51648 12 +Glycosphingolipid metabolism 0.8000590434489057 3.31156648691371 0.0009277519118084 0.7227257721428113 0.0761286292355576 14 P06280,P07602,P17900,Q9NZJ7,P04062,P10619,P06865,Q13510 8 +Glycosaminoglycan metabolism 0.75789603717125 3.2302518182932354 0.0012368123093311 0.8191943370351755 0.0813940291188403 16 O43505,Q96L58,P16278,Q7LGA3,P06865,Q8NCH0,Q9NRB3,Q8TB61,P15586,P08236,P54802 11 +Phospholipid metabolism 0.54091222080135 3.10663759810039 0.0018922822100309 0.9270230342903204 0.1174467410394331 49 Q8WUK0,Q96N66,P43304,Q9UG56,Q10713,Q8NF37,Q8IV08,Q08AM6,Q9BTU6,Q8NCC3,Q53H12,O14735,Q7L5N7,O95674,P40939,Q96PE3,Q9NUQ2,P61106,Q9NPH0,Q9NTJ5,Q86UL3,Q8NEB9,P48739,Q9NP80,Q9NQZ5,Q9HBU6,Q92604 27 +Slc mediated transmembrane transport 0.6789586652688007 3.0259613627390545 0.0024784397113257 0.9675954128602242 0.1317386031173931 20 P05141,P12235,P12236,O00400,Q99808,Q8TB61,Q9UBX3,Q70HW3 8 +Mitochondrial calcium ion transport 0.7103799884268353 2.9510796829018897 0.0031666521199917 0.987515370403098 0.1330627952744756 16 Q99623,Q8IYU8,Q9H4I9,O95202,P45880,Q9Y277,Q9UJZ1,Q10713,P21796 9 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.4968444293724483 2.9117402884137675 0.0035942134054303 0.9930994279649896 0.1330627952744756 61 Q86Y39,Q9Y6N1,O96000,Q8N8Q8,Q9UDW1,P00846,O75880,Q9P0J0,O14949,P24539,O75438,P21912,Q96I36,P13073,P03886,O75964,O43676,O14548,P56385,O75306,Q9NPL8,O95168 22 +Transport of small molecules 0.4803880009183197 2.9096412436013614 0.003618438457821 0.9933274365186509 0.1330627952744756 147 Q9BUN8,Q99623,P98194,O15118,Q9H4I9,Q15904,P09601,P20020,Q9Y6B6,P05141,P12236,Q9UJZ1,P35613,Q10713,Q9UBV2,P61916,P28288,P63218,Q9BPX6,P30519,Q9H0U3,Q92530,P49721,Q9C0H2,P12235,P45880,O00231,Q9HD20,O00400,Q96PU5,P27105,P07237,P61289,P53680,Q9UBX3,Q70HW3,Q99797,Q99808,P25787,Q9UNS2,Q9H936,P35610,P28070,P54709,P16615,P10644,Q86WC4,Q93050,O94905,P21796,Q9Y487,Q8WTV0,P28072,Q8IYU8,P40855,O95202,O75027,Q9Y277,P05023,Q8N4V1,Q8TDW0,Q8TB61,P55011,Q9BU23 64 +Glycerophospholipid biosynthesis 0.5775029502859994 2.8909969835905365 0.0038402180625167 0.9950944982295756 0.1330627952744756 32 Q8WUK0,Q96N66,P43304,Q9UG56,Q8NF37,Q8IV08,Q8NCC3,Q53H12,O14735,Q7L5N7,O95674,P40939,Q9NUQ2,Q9NPH0,Q86UL3,P48739,Q9NP80,Q9NQZ5,Q9HBU6,Q92604 20 +Mitophagy 0.7347699352653518 2.7135108123447114 0.0066574395630336 0.9999020784826854 0.1566610825188676 12 Q96B49,Q9NS69,Q8N4H5 3 +Cristae formation 0.6210003227940302 2.6967673826648904 0.0070016161557771 0.9999393424907213 0.1608050878266943 21 Q13505,Q9NVH1,P56385,P56134,P24539,P06576,P17152,O75964,Q16891,Q9BUR5,P00846,Q9NX63,Q9Y512,Q5XKP0 14 +Gpcr ligand binding 0.7786409167831546 2.6508693835595944 0.0080284883118602 0.9999854824197127 0.164616869587377 10 P07602,Q9NZJ7,P42892,P04083,P05067,P63218 6 +Respiratory electron transport 0.479674164540197 2.5537228131208916 0.0106578063840245 0.9999996293992472 0.1687214637232732 51 Q9P0J0,O75306,P03886,Q9NPL8,P21912,O14949,Q86Y39,Q9Y6N1,O96000,O75438,O95168,O43676,Q8N8Q8,Q9UDW1,O75880,Q96I36,P13073 17 +Cargo concentration in the er 0.6556826474807004 2.5475221908173498 0.0108490952802735 0.9999997163076456 0.1687214637232732 15 Q96PC5,Q12907,P49755,O14653,Q9Y6B6,Q15363,O75396,Q5JRA6,Q9HCU5,Q13190 10 +Pink1 prkn mediated mitophagy 0.7952776239193601 2.5385757118456507 0.0111304716643836 0.999999808534578 0.1690363938481119 9 Q96B49,Q9NS69,Q8N4H5 3 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.6286774574332701 2.519969030512148 0.0117365159999276 0.9999999179386602 0.1725517565095745 17 O43852,Q07065,O76024,P07237,Q5JRA6,Q02818,P05067 7 +Peptide ligand binding receptors 0.8269839765727292 2.4763332886398306 0.0132739600464932 0.9999999904569612 0.1784311430902361 7 P07602,Q9NZJ7,P42892,P04083,P05067 5 +Class a 1 rhodopsin like receptors 0.8269839765727292 2.4763332886398306 0.0132739600464932 0.9999999904569612 0.1784311430902361 7 P07602,Q9NZJ7,P42892,P04083,P05067 5 +G alpha q signalling events 0.6900742479162625 2.464465810761928 0.0137217653781507 0.999999994903891 0.180604569072422 12 P51812,Q8NCG7,Q05655,P04083,P05067,P63218 6 +Transport of vitamins nucleosides and related molecules 0.8082064628950179 2.4248969630231305 0.0153127321164583 0.9999999994526292 0.1959462572680132 8 P12235,P12236,O00400,Q8TB61,Q99808 5 +Ras processing 0.8809716448116166 2.381088606489777 0.0172615593809171 0.9999999999645808 0.2056506471071331 5 O60725,P49356 2 +Heparan sulfate heparin hs gag metabolism 0.8731466227347584 2.3477147156485585 0.0188889826319451 0.999999999996415 0.2189470716136645 5 P08236,Q7LGA3,P16278,P54802 4 +Organelle biogenesis and maintenance 0.4020583883486007 2.333028247364234 0.019646662814174 0.9999999999987674 0.2207454309690124 91 Q13409,Q92845,O75935,Q15154,Q10713,P00846,P41208,Q92973,Q96RR1,P24539,P17152,P04350,Q9BUR5,Q9Y512,O95684,O43924,A6NIH7,Q9NVH1,P06576,O75964,P56385,Q13505,O94927,P56134,O43805,Q96CS2,Q16891,Q9H6D7,Q9NX63,Q5XKP0 30 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7096927864572864 2.293293352856806 0.0218311216692557 0.9999999999999436 0.2297047928180156 10 P09601,P46379,P50402,P51648,P05067,Q13190 6 +Processing of smdt1 0.6849425902709492 2.2914056044160565 0.021939965739492 0.9999999999999516 0.2297047928180156 11 Q9BPX6,Q99623,Q8IYU8,Q9H4I9,Q9UJZ1,Q10713 6 +Cholesterol biosynthesis 0.5995080957875276 2.2600633181355767 0.0238173213500738 0.9999999999999966 0.2336418035188761 16 Q16850,Q14534,Q9BWD1,Q15800,Q9H2C2,P14324,Q14739,Q15392 8 +Ion channel transport 0.5149181219928743 2.259737456407572 0.0238375501419403 0.9999999999999968 0.2336418035188761 28 P98194,Q15904,P20020,Q9C0H2,P54709,P16615,Q9HD20,Q93050,Q86WC4,Q96PU5,P27105,P51790,P05023,Q9Y487 14 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.8495582553151277 2.2463367763006965 0.0246824446369713 0.999999999999999 0.2366388434178515 5 P12236,P12235,Q99808 3 +Diseases of glycosylation 0.5603907197116863 2.224868228288659 0.0260900854593075 1.0 0.2449770936571038 20 O43505,P16278,Q86SQ9,P10619,Q9BV10,P06865,Q8NCH0,Q9BT22 8 +Ire1alpha activates chaperones 0.5126548043638779 2.1898785830632734 0.0285330436022241 1.0 0.2537038128466787 26 Q9Y5M8,P43307,O43731,O76024,O14653,O43909,O95070,O14773,Q9NWM8 9 +Keratan sulfate keratin metabolism 0.78477676223988 2.182736355616873 0.0290552309776401 1.0 0.2540749434576787 6 O43505,P15586,P16278,P06865 4 +Sphingolipid de novo biosynthesis 0.6633233645447292 2.1710033181828026 0.0299309215522209 1.0 0.2569225688519839 11 O95470,Q06136,Q96G23,P51648 4 +Class i peroxisomal membrane protein import 0.7128811105358535 2.128375740629424 0.0333059428704671 1.0 0.2803350238594569 9 O75381,Q8TB36,P40855,Q9Y5Y5,P51648,P28288,O43808 7 +Mitochondrial biogenesis 0.4798935476046322 2.1168784226858945 0.0342701673750802 1.0 0.2836010258225205 33 Q13505,Q9NVH1,P56385,P56134,Q5XKP0,P24539,Q96RR1,P17152,P06576,O75431,O75964,Q16891,Q9BUR5,P00846,Q9NX63,Q9Y512,Q04837,P36542 18 +Chondroitin sulfate dermatan sulfate metabolism 0.8145607446144901 2.093792739116455 0.0362784472612562 1.0 0.2931977433629016 5 Q96L58,P06865,Q8NCH0 3 +The citric acid tca cycle and respiratory electron transport 0.3809816325040039 2.0276211446931653 0.0425989292613702 1.0 0.3199550013000741 94 Q86Y39,Q9Y6N1,O96000,P35613,Q9UDW1,Q8N8Q8,P00846,O75880,Q9P0J0,O14949,P24539,O75438,Q96I36,P13073,P03886,O75964,O43676,P21796,P56385,O43708,O75306,Q9NPL8,Q13423 23 +Intra golgi traffic 0.5789078049212847 2.0049836459361288 0.0449647954151282 1.0 0.3317455783254596 14 O00461,O14653,Q8TBA6,O43752,O95721,O95249,Q13190 7 +Phase i functionalization of compounds 0.6104401584759498 2.0012173837354794 0.0453689683817017 1.0 0.3317455783254596 12 O43169,P00387,P07099,P16435 4 +Iron uptake and transport 0.5358197484184533 1.9661702798114016 0.0492789443154237 1.0 0.3516182367210906 18 P09601,Q9Y487,P30519 3 +Diseases associated with glycosaminoglycan metabolism 0.7821539951338133 1.9503044310937032 0.0511398448487259 1.0 0.3516182367210906 5 Q96L58,P06865,Q8NCH0 3 +Transport of inorganic cations anions and amino acids oligopeptides 0.7078020941395191 1.942920897430069 0.052025716582543 1.0 0.3524487270444829 8 Q8N697,Q9H936,P08195,Q9UBX3,Q70HW3,P55011 6 +Recruitment of mitotic centrosome proteins and complexes 0.4643152180076936 1.9195622142614863 0.0549132207365627 1.0 0.3610797899087555 31 O95684,O94927,Q13409,O43805,O75935,Q96CS2,Q9H6D7,Q15154,Q9BSJ2,P41208 10 +Synthesis of pips at the late endosome membrane 0.7692126994439614 1.8924188441744805 0.0584351972357946 1.0 0.3726211350740966 5 Q8NEB9 1 +Platelet activation signaling and aggregation 0.4171873700821644 1.8845930403322764 0.0594848026610019 1.0 0.3767315888102558 48 O43852,Q92520,P07602,Q9NZJ7,Q9NTK5,Q8NCG7,Q9Y6I9,Q8NBX0,Q9UEU0,O94919,Q96JJ7,Q05655,Q9NUQ9,P05067,P63218 15 +Pre notch processing in golgi 0.7671028765660223 1.882950833287465 0.0597070313436964 1.0 0.3767315888102558 5 P16615,P15291,Q9UBV2 3 +Interleukin 4 and interleukin 13 signaling 0.5884666447533686 1.868904374681725 0.061636119582678 1.0 0.3785827433922711 12 P09601,P08670,P04083 3 +Complex i biogenesis 0.4714995238601558 1.8559966374769628 0.063454037339121 1.0 0.3880242460294923 26 Q9P0J0,O75306,P03886,Q9NPL8,Q86Y39,O96000,O75438,O43676 8 +Synthesis of pa 0.6937244781585894 1.8421895105218455 0.0654474342413324 1.0 0.3947224564533397 7 Q86UL3,Q9NUQ2,Q9NPH0,Q8NF37,P43304 5 +Response to elevated platelet cytosolic ca2 0.4601131584077924 1.829842346104709 0.0672735166251761 1.0 0.3951712524748005 29 O43852,Q92520,P07602,Q9NZJ7,Q9NTK5,Q9Y6I9,O94919,Q96JJ7,Q9NUQ9,P05067 10 +Stimuli sensing channels 0.6551023045666197 1.8284488810089128 0.0674822109870136 1.0 0.3951712524748005 9 Q9C0H2,Q86WC4 2 +Phosphorylation of the apc c 0.6232547184742521 1.822229001724217 0.0684202457965557 1.0 0.3981588483857349 10 Q96DE5,Q9UJX2 2 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.6883221588435018 1.8155129770690248 0.0694451135239011 1.0 0.3985005132238768 7 Q96DE5,Q9UJX2 2 +Mucopolysaccharidoses 0.8748353096179224 1.7925770183925422 0.0730405838611509 1.0 0.4072605468524312 4 P16278,P15586,P08236 3 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.5061502266366903 1.7919523178104564 0.073140604327581 1.0 0.4072605468524312 19 Q86YN1,Q86SQ9,P10619,Q9BV10,Q9BT22 5 +Metabolism of steroid hormones 0.7016264531648376 1.790474744100598 0.0733776238540198 1.0 0.4072605468524312 6 Q14849,Q53GQ0,O95772 3 +Synthesis of dolichyl phosphate 0.9562211981566752 1.7865332777332177 0.0740129540640834 1.0 0.4091436100662535 2 Q86YN1 1 +Apc c cdc20 mediated degradation of cyclin b 0.6439290119855796 1.7692968155208202 0.0768443545965986 1.0 0.4136261678514749 9 Q96DE5,Q9UJX2 2 +Transcriptional regulation by ventx 0.593142282478164 1.7682292990468411 0.0770225779484343 1.0 0.4136261678514749 11 Q9HCE1,Q96DE5,Q9UJX2 3 +Aurka activation by tpx2 0.4416975004584172 1.748487390224284 0.080379667217302 1.0 0.415734804469576 32 O95684,O94927,Q13409,O14965,O43805,O75935,Q9H6D7,Q15154,Q96CS2,P41208 10 +Keratan sulfate degradation 0.8640352416981014 1.7482803991311706 0.0804154856017387 1.0 0.415734804469576 4 P15586,P06865 2 +Miscellaneous transport and binding events 0.6926355365573174 1.7470995965283036 0.0806200633848381 1.0 0.415734804469576 6 Q8TDW0,Q9H0U3,Q8N4V1 3 +Anchoring of the basal body to the plasma membrane 0.4410480404574654 1.7152706608483366 0.086295615034728 1.0 0.4307594572053179 31 O95684,O94927,Q13409,O43805,O75935,Q9H6D7,Q15154,Q96CS2,P41208 9 +Synthesis of very long chain fatty acyl coas 0.6615286996012111 1.7116440094088576 0.0869622927353717 1.0 0.4307594572053179 8 Q9P035,Q9UKU0,Q53GQ0 3 +Tp53 regulates metabolic genes 0.4201760509822201 1.707693011723944 0.0876933195159117 1.0 0.4312888525658008 37 Q9Y6N1,P31751,Q8N8Q8,P62258,O75880,P20674,Q04917,Q9Y2Q5,O43819,P04637,Q9HCE1,P00403,Q15382,Q96I36,P13073,O00483,O14548,P42345,P54646,Q9NQ88,P54619 21 +Formation of atp by chemiosmotic coupling 0.5971696372732322 1.675122253004734 0.0939102476728837 1.0 0.4545081401875916 10 P24539,O75964,P00846 3 +Diseases of carbohydrate metabolism 0.5739356201706809 1.6548984937314033 0.0979450898675642 1.0 0.4590190758929653 11 P16278,P54802,P10253,O43826,P15586,P08236 6 +Signaling by gpcr 0.4026679487658131 1.6480962269680657 0.0993329264460822 1.0 0.4622158395571908 40 Q9NRV9,P51812,P07602,Q9NZJ7,Q8NCG7,P42892,Q05655,P04083,P52292,P05067,P63218 11 +Heme degradation 0.9479598275876996 1.6434021774605625 0.1002997499126365 1.0 0.4651485046284018 3 P09601 1 +G alpha z signalling events 0.6706722503228951 1.640411334512631 0.1009196702184613 1.0 0.4661012531794593 6 Q05655 1 +Rhoa gtpase cycle 0.3941274221215545 1.605616246658163 0.1083582535449301 1.0 0.4862048909061475 42 P30519,Q96HY6,Q8NBN3,O15173,Q14739,P27105,P42167,Q13190 8 +Synthesis of pc 0.7056365396446584 1.603544980046378 0.1088143868239437 1.0 0.4866714646947904 5 Q9NQZ5 1 +Synthesis of pips at the golgi membrane 0.5815697543985933 1.5861123213171608 0.1127138323255108 1.0 0.4937768166916666 10 Q08AM6,Q10713,Q8NEB9,Q9NTJ5 4 +Rac2 gtpase cycle 0.4245175144952093 1.5676645505804117 0.1169594388642913 1.0 0.4958219156762291 31 Q13505,Q9UH62,O15173,Q14739,Q9Y512,Q86XL3,P42167 7 +G alpha i signalling events 0.4482500805534581 1.5601825774811875 0.1187167416110117 1.0 0.4992048022230228 24 Q9NRV9,P07602,Q9NZJ7,Q05655,P04083,P52292,P05067,P63218 8 +Transport to the golgi and subsequent modification 0.3414508882670501 1.55502121398948 0.1199410170427397 1.0 0.4992048022230228 79 Q13409,P49755,O75935,Q9Y6B6,O75396,Q5JRA6,Q9HCU5,P24390,P04350,Q9Y3B3,P15291,O14579,Q13190,P56962,O43731,P04066,O14653,Q15363,O15155,O95249,Q9H9E3,Q96PC5,Q12907,Q9UJW0,Q9H0U4 25 +Plasma lipoprotein remodeling 0.8992758393679958 1.5451575835801223 0.1223081513211741 1.0 0.4992048022230228 2 Q9BU23 1 +Purinergic signaling in leishmaniasis infection 0.8143905712046413 1.5429837634502257 0.122834715449215 1.0 0.4992048022230228 4 P09601 1 +Inflammasomes 0.8143905712046413 1.5429837634502257 0.122834715449215 1.0 0.4992048022230228 4 P09601 1 +The nlrp3 inflammasome 0.8143905712046413 1.5429837634502257 0.122834715449215 1.0 0.4992048022230228 4 P09601 1 +Recruitment of numa to mitotic centrosomes 0.4115870782874686 1.5300537163304415 0.1260034333085309 1.0 0.5075108406787767 34 O94927,Q13409,O43805,O75935,Q9H6D7,Q96CS2,P41208 7 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.5701496436884268 1.5204862565417756 0.1283888102916421 1.0 0.5113352617378948 10 P38435,O60725,Q9BU89 3 +Selective autophagy 0.4114347004498535 1.474223424058242 0.1404214450091647 1.0 0.5316779095963444 32 Q96B49,Q9NS69,Q8N4H5 3 +Asparagine n linked glycosylation 0.3558715394101133 1.4685749441599711 0.1419481149910813 1.0 0.534119278860393 118 Q9BUN8,Q86YN1,Q13409,Q86SQ9,P49755,O75935,P27824,O75396,Q9BV10,Q9BT22,Q5JRA6,Q9HCU5,Q9UBV2,P24390,P16278,Q9H0U3,Q9Y3B3,P15291,O14579,Q13190,P56962,O43731,P04066,O14653,Q15363,O15155,P10619,O95249,Q9H9E3,P46977,Q96PC5,P04844,Q12907,Q9UJW0,Q9H0U4 35 +Cytochrome p450 arranged by substrate type 0.902192199739819 1.4643862166078827 0.1430884520029041 1.0 0.5359030912412288 3 P16435 1 +Biological oxidations 0.3838237022736543 1.456717677666165 0.1451943280103267 1.0 0.5411761310200268 40 O43169,Q16850,P78417,P07099,P00387,P16435,P21964,Q9UJ14,O43708,Q8TB61 10 +Metabolism of lipids 0.3863672558370709 1.4564091243743795 0.1452795547094283 1.0 0.5411761310200268 182 Q16850,Q96G23,P07602,Q9NZJ7,P23786,Q96N66,Q99538,Q8WUK0,Q9UG56,Q9H2C2,P14324,Q10713,Q15392,Q06136,P50897,Q8NF37,Q8IV08,O43808,Q9NZ01,Q9NXE4,Q14849,Q9BTU6,Q08AM6,P06280,O15254,P16278,O95470,Q8NCC3,P17900,Q53H12,O95674,O15269,P04062,Q13510,Q8NBQ5,P51648,O95772,Q14534,P50416,Q53GQ0,Q15165,P09960,Q9NUQ2,Q9UKU0,Q9NPH0,O75192,Q15067,P10619,Q9NTJ5,Q9UMR5,P37268,Q9P035,P38435,Q9BWD1,Q8NEB9,Q15800,Q9NP80,Q9NQZ5,Q14739,Q96SU4,P06865,Q9HBU6,Q8IVS2,Q16836 64 +Energy dependent regulation of mtor by lkb1 ampk 0.6158151183136645 1.4508802404290833 0.1468132109904267 1.0 0.5439567227580959 7 P54619,P42345,Q15382,P54646,Q9Y2Q5 5 +Integrin cell surface interactions 0.7907993956949794 1.4446389481048587 0.1485593267743461 1.0 0.5489545176527977 4 Q08722 1 +Hyaluronan metabolism 0.6691940076276093 1.435048720570731 0.1512732146330511 1.0 0.5535876453617652 5 P06865 1 +Hyaluronan uptake and degradation 0.6691940076276093 1.435048720570731 0.1512732146330511 1.0 0.5535876453617652 5 P06865 1 +Synthesis of pips at the early endosome membrane 0.6114211211533747 1.4284290847366483 0.1531683926605311 1.0 0.5535876453617652 7 Q08AM6,Q8NEB9 2 +Aquaporin mediated transport 0.6655002086967691 1.4178766087907964 0.1562267926848399 1.0 0.554195091327854 5 Q99797,P63218 2 +Pregnenolone biosynthesis 0.7839303769404393 1.4159344278621189 0.1567947038416721 1.0 0.554195091327854 4 Q14849 1 +Pi metabolism 0.4591898331424969 1.4105571353628064 0.158375238251343 1.0 0.5569327716624837 18 Q08AM6,Q9BTU6,Q8NEB9,Q96PE3,P48739,Q10713,Q9NTJ5 7 +Attachment of gpi anchor to upar 0.6589785831960411 1.3875231520002274 0.1652822964127946 1.0 0.5710503341062056 5 Q9H490,Q92643,O43292,Q96S52 4 +Intra golgi and retrograde golgi to er traffic 0.3355355525217974 1.3831410759744387 0.1666216129544875 1.0 0.572813604734084 96 Q13409,Q92845,P49755,O75935,Q6NUQ1,O75396,P40616,P24390,Q9P2W9,Q9Y3B3,O14579,Q13190,O15260,O43731,O14653,Q15363,Q12981,O95721,O95249,Q10471,Q9H9E3,O00461,Q8TBA6,O43752,Q10472,Q9UJW0,Q15042,Q7Z6M1,Q9H0U4 29 +Autophagy 0.3663140832063759 1.363042650405922 0.1728690693143406 1.0 0.5835144456842721 51 Q676U5,Q9NS69,Q8N4H5,P21796,Q96B49 5 +Cytoprotection by hmox1 0.3511018815906774 1.3572997380837353 0.174685990534825 1.0 0.5835144456842721 65 P30519,Q9Y6N1,P49721,P09601,P28070,Q05655,Q8N8Q8,P61289,O75880,Q96I36,P13073,Q8TCT9 12 +Hs gag degradation 0.8745472505762246 1.3559412688865249 0.1751178554621961 1.0 0.5835144456842721 3 P16278,P08236 2 +Cilium assembly 0.3594150482578063 1.3549902431627912 0.1754206656245736 1.0 0.5835144456842721 58 O94927,O43924,Q13409,A6NIH7,O43805,O75935,Q9H6D7,Q10713,Q96CS2,P41208 10 +Initiation of nuclear envelope ne reformation 0.4446740092478055 1.3335274337463217 0.1823587788437333 1.0 0.5835144456842721 19 Q14739,Q86XL3,Q8IXJ6,P42167 4 +Unfolded protein response upr 0.3682366309162544 1.3327946411327312 0.1825992048130993 1.0 0.5835144456842721 41 Q9Y5M8,P43307,O43731,O76024,O14653,O43909,O95070,O14773,Q9NWM8 9 +Post translational modification synthesis of gpi anchored proteins 0.5876409761252955 1.3316678272331437 0.1829693658067808 1.0 0.5835144456842721 8 Q92643,Q5H8A4,Q9H490,O60762,Q96S52,O43292 6 +Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.5628193404335439 1.3298034956155085 0.1835830239140925 1.0 0.5835144456842721 9 Q9UJX3,Q96DE5,Q9UJX2 3 +Apc cdc20 mediated degradation of nek2a 0.5628193404335439 1.3298034956155085 0.1835830239140925 1.0 0.5835144456842721 9 Q9UJX3,Q96DE5,Q9UJX2 3 +Tyrosine catabolism 0.8469387755101948 1.3227520722085748 0.1859178404996173 1.0 0.5835144456842721 2 O43708 1 +Er to golgi anterograde transport 0.3286893489428616 1.2983527193666995 0.1941661581916327 1.0 0.5856293565480265 76 Q13409,P49755,O75935,Q9Y6B6,O75396,Q5JRA6,Q9HCU5,P24390,P04350,Q9Y3B3,O14579,Q13190,P56962,O43731,O14653,Q15363,O15155,O95249,Q9H9E3,Q96PC5,Q12907,Q9UJW0,Q9H0U4 23 +Basigin interactions 0.6345832078121802 1.273654555116397 0.2027858687436747 1.0 0.6039872211287899 5 P08195,P54709,P35613 3 +Sulfur amino acid metabolism 0.5495799896089244 1.2566499439160388 0.2088804211897463 1.0 0.6181429166685857 9 Q9UBX3 1 +Regulation of plk1 activity at g2 m transition 0.3730523928953106 1.246654641957135 0.2125241569144924 1.0 0.6220853206888105 37 O95684,O94927,Q13409,O14965,O43805,O75935,Q9H6D7,Q15154,Q96CS2,P41208 10 +Effects of pip2 hydrolysis 0.8463714746269906 1.2454676683338213 0.2129598929564573 1.0 0.6220853206888105 3 Q8NCG7 1 +Vitamin c ascorbate metabolism 0.8459192987341007 1.2436968402460684 0.2136111593645959 1.0 0.6220853206888105 3 P78417 1 +Rho gtpases activate nadph oxidases 0.5901834608038499 1.2420652806788104 0.2142124772178197 1.0 0.6220853206888105 6 Q8NEB9 1 +Rab geranylgeranylation 0.4428122216314381 1.2336087968636105 0.2173487134491221 1.0 0.6249711302735506 17 Q15907,P61019,Q969Q5,P61026,Q9H0U4 5 +Formyl peptide receptors bind formyl peptides and many other ligands 0.8426078366809275 1.2307314000975356 0.2184233400304811 1.0 0.6249711302735506 3 P05067,P04083 2 +Cellular response to chemical stress 0.3247708467028705 1.2207806198054851 0.2221690935062854 1.0 0.6304675302375493 75 P30519,Q9Y6N1,P49721,P09601,P28070,Q96HE7,P07237,Q8N8Q8,Q05655,P61289,O75880,Q96I36,P13073,Q8TCT9 14 +Role of phospholipids in phagocytosis 0.7361009186545058 1.2156217576145636 0.2241290419438633 1.0 0.6347260982918423 4 Q8IV08 1 +Metabolism of steroids 0.3550785881215485 1.2013956446704943 0.2295977647887555 1.0 0.6473538437718823 44 Q14849,Q16850,Q14534,O95772,P38435,Q53GQ0,Q9BWD1,Q15800,Q9H2C2,P04062,Q14739,Q15392,Q96SU4 13 +Antigen presentation folding assembly and peptide loading of class i mhc 0.4548385865190468 1.1792500723326826 0.2382986128017734 1.0 0.6539506460601505 14 P10321,P51572,P27824,P04439,Q9NZ08,Q03518 6 +Keratan sulfate biosynthesis 0.8127057274522719 1.1780464104396002 0.238778104508796 1.0 0.6539506460601505 2 O43505 1 +Vitamin d calciferol metabolism 0.8274613105037789 1.171510591086495 0.241393603189421 1.0 0.6554144589543809 3 P38435,P04062 2 +Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.5556575868560434 1.1640978524354746 0.2443843588644121 1.0 0.6622336940208188 8 Q96DE5,Q9UJX2 2 +N glycan antennae elongation in the medial trans golgi 0.8077682685977624 1.1572843432935744 0.2471562080862368 1.0 0.665230152300119 2 P15291 1 +Miro gtpase cycle 0.607578253706752 1.1472667819454008 0.2512713783894169 1.0 0.6716770695051726 5 O95140,Q8IXI1,Q8IWA4,Q8IXI2 4 +Nuclear envelope ne reassembly 0.3478942052978755 1.144775622813975 0.252302115870431 1.0 0.6722974593280532 49 Q8IXJ6,Q92973,Q12769,Q7Z3B4,Q8NFH4,Q8NFH5,Q9BTX1,Q14739,Q9BW27,P50402,Q86XL3,Q8N1F7,P42167 13 +Synthesis of substrates in n glycan biosythesis 0.4437129339587078 1.1443551082843912 0.2524763975334729 1.0 0.6722974593280532 15 Q86YN1,P10619,Q86SQ9 3 +Metabolism of porphyrins 0.5282066724913741 1.1379972148805808 0.2551216453074096 1.0 0.678034834259308 9 P09601,P30519 2 +Synthesis of pg 0.8169245966414135 1.1304166937310265 0.2583006831191534 1.0 0.6851661114600193 3 Q8WUK0,Q8IV08 2 +Ros and rns production in phagocytes 0.5258654343713086 1.1249683665889727 0.2606024392741857 1.0 0.6870648537855577 9 Q9Y487 1 +Noncanonical activation of notch3 0.7995391705069095 1.1227625465201154 0.2615383560431934 1.0 0.6870648537855577 2 Q92542 1 +Vitamin b5 pantothenate metabolism 0.712052121630615 1.1149737496108925 0.2648616708651499 1.0 0.6893386612723863 4 Q13057,Q9NRN7 2 +Ion transport by p type atpases 0.4991521507129082 1.1053030754226547 0.2690282857674131 1.0 0.6966236673647883 10 P98194,P20020,P16615,Q9HD20,P05023 5 +Signaling by insulin receptor 0.4251655410657194 1.1038066149424397 0.2696770347613326 1.0 0.6966236673647883 17 Q8NEB9,Q9Y487 2 +Incretin synthesis secretion and inactivation 0.7065238159293575 1.0918840031677717 0.2748840898196034 1.0 0.7048048462536028 4 P67812 1 +Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.7065238159293575 1.0918840031677717 0.2748840898196034 1.0 0.7048048462536028 4 P67812 1 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.4952949886042336 1.082498555756383 0.2790310567966672 1.0 0.7101674410552377 10 P09601 1 +O linked glycosylation 0.8030951596970617 1.076651957787676 0.2816357827353761 1.0 0.7137898387454359 3 Q10472,O43505 2 +O linked glycosylation of mucins 0.8030951596970617 1.076651957787676 0.2816357827353761 1.0 0.7137898387454359 3 Q10472,O43505 2 +Copi mediated anterograde transport 0.3388077436627989 1.0758288652698524 0.2820038002568799 1.0 0.7137898387454359 54 Q13409,P24390,O43731,P49755,O75935,O14653,Q15363,O15155,Q9UJW0,Q9Y3B3,O95249,O14579,Q9H0U4,Q13190 14 +Acyl chain remodelling of pc 0.7018629335735106 1.072437029506197 0.2835237833696142 1.0 0.7144052545040539 4 Q8NF37,Q9NP80 2 +Methylation 0.5557320435143169 1.0694816370362266 0.2848526988903481 1.0 0.7144052545040539 6 P21964 1 +Chylomicron assembly 0.7860434496379081 1.066402871307408 0.2862415642878013 1.0 0.7144052545040539 2 P07237 1 +Plasma lipoprotein assembly 0.7860434496379081 1.066402871307408 0.2862415642878013 1.0 0.7144052545040539 2 P07237 1 +Alpha oxidation of phytanate 0.6995135118101794 1.06264208264155 0.2879442951654987 1.0 0.7157176545300705 4 P51648 1 +Metabolism of folate and pterines 0.5332236173912349 1.045988914039233 0.2955661507597575 1.0 0.7241790636619592 8 Q9H2D1 1 +Abc transporters in lipid homeostasis 0.7801184990124853 1.041775273060769 0.297515880787178 1.0 0.7241790636619592 2 P40855 1 +Synthesis of pe 0.7927899296289127 1.036744673811273 0.2998548660751123 1.0 0.7244745190835756 3 Q9UG56 1 +Copii mediated vesicle transport 0.3611828994525264 1.0274211160613411 0.304222212595693 1.0 0.7324653271903271 33 P56962,Q12907,P49755,Q8WVM8,O15498,Q9Y6B6,O00743,O14653,O15027,Q15363,Q9H0U4,O75396,O15155,O43617,P53634,Q9HCU5,Q13190 17 +Glycogen storage diseases 0.5800653241242104 1.018620580188804 0.3083831300174084 1.0 0.7386230254489748 5 P46976,P10253,O43826 3 +Diseases associated with n glycosylation of proteins 0.5436408692314776 1.0089157240746154 0.3130150534663984 1.0 0.7445556005001078 6 Q9BV10 1 +Postmitotic nuclear pore complex npc reformation 0.3856912952935273 1.0028692941043482 0.3159239296219613 1.0 0.7476145046875866 23 Q92973,Q7Z3B4,Q8NFH4,Q8NFH5,Q9BTX1,Q9BW27,Q8N1F7 7 +Nr1h2 and nr1h3 mediated signaling 0.5748980622207742 0.9945238709187958 0.3199678898848845 1.0 0.7524311722328386 5 P49327,Q8NB78,Q9HCE1 3 +Cardiac conduction 0.4620142731819942 0.9739822213599364 0.3300653667698521 1.0 0.7564682203581021 11 P20020,P05023,P16615,Q9HD47 4 +Translation of sars cov 2 structural proteins 0.4132067716322176 0.970346731321034 0.3318736911248106 1.0 0.7580304823057056 16 P04844,Q9H0U3,P27824,Q10472,P46977 5 +Insulin receptor recycling 0.4734539848003234 0.9532316504721228 0.3404727133695659 1.0 0.75845910460066 10 Q9Y487 1 +Rnd2 gtpase cycle 0.4258356143834306 0.9442404418115976 0.3450467932188772 1.0 0.75845910460066 13 P51648 1 +Endosomal vacuolar pathway 0.670153404391755 0.9408261396926229 0.3467939629909498 1.0 0.75845910460066 4 P04439,Q9UIQ6 2 +Platelet calcium homeostasis 0.7677251592583709 0.9404080138147544 0.3470083131498578 1.0 0.75845910460066 3 P16615 1 +Reduction of cytosolic ca levels 0.7677251592583709 0.9404080138147544 0.3470083131498578 1.0 0.75845910460066 3 P16615 1 +Metabolism of fat soluble vitamins 0.5629875002196014 0.9391136808046194 0.3476723809185098 1.0 0.75845910460066 5 Q8N0U8 1 +Formation of fibrin clot clotting cascade 0.7544437129690535 0.9360632657028788 0.3492406150168121 1.0 0.75845910460066 2 Q07021 1 +Intrinsic pathway of fibrin clot formation 0.7544437129690535 0.9360632657028788 0.3492406150168121 1.0 0.75845910460066 2 Q07021 1 +Gaba receptor activation 0.526336689519611 0.9224436983732138 0.3562971850921501 1.0 0.7651259039053652 6 P63218 1 +Rhog gtpase cycle 0.3479214948822249 0.9219742111298034 0.3565420275796347 1.0 0.7651259039053652 34 O95202,O15173,Q14739,Q86XL3,P42167,Q13190 6 +Copi dependent golgi to er retrograde traffic 0.3271252381940825 0.9128073892471664 0.3613438513655389 1.0 0.7664962489145426 49 O15260,P24390,Q92845,O43731,P49755,Q9P2W9,Q6NUQ1,Q15363,O75396,Q12981,Q9Y3B3,O14579,Q9H0U4 13 +Acyl chain remodelling of pg 0.7478604344963744 0.9092678608198492 0.363208751094735 1.0 0.7664962489145426 2 Q8NF37 1 +Synthesis of bile acids and bile salts 0.523202814273737 0.9068246855885173 0.3644995135627089 1.0 0.7664962489145426 6 Q96SU4 1 +Bile acid and bile salt metabolism 0.523202814273737 0.9068246855885173 0.3644995135627089 1.0 0.7664962489145426 6 Q96SU4 1 +Ptk6 regulates proteins involved in rna processing 0.7579848534738152 0.9033151926034222 0.366358635566993 1.0 0.7671327793236127 3 Q07666,O75525 2 +Cd28 dependent pi3k akt signaling 0.7439104674127726 0.8932606615538128 0.3717175992716015 1.0 0.7760026015005337 2 P42345 1 +Transferrin endocytosis and recycling 0.4468259951834339 0.8803149058041432 0.378688739917512 1.0 0.7819311855994869 11 Q9Y487 1 +Metabolism of cofactors 0.5172464977706503 0.8771857085599816 0.3803857772809764 1.0 0.7827739676431957 6 P00374 1 +Peroxisomal lipid metabolism 0.4462464453499282 0.8767448176859692 0.380625257783088 1.0 0.7827739676431957 11 Q15067,P51648,O15254,O43808 4 +Hur elavl1 binds and stabilizes mrna 0.5163700130348509 0.8728299838599685 0.3827557539232495 1.0 0.7848196616052387 6 Q05655 1 +Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.7488153247747573 0.868608035090577 0.385061558069854 1.0 0.7860488526625379 3 P67812 1 +Synthesis secretion and deacylation of ghrelin 0.7488153247747573 0.868608035090577 0.385061558069854 1.0 0.7860488526625379 3 P67812 1 +Maturation of sars cov 2 spike protein 0.4540349661431631 0.8384433189258902 0.4017817688756546 1.0 0.8079484821871163 10 P04844,P46977,P27824 3 +Plasma lipoprotein assembly remodeling and clearance 0.3948249454518816 0.837822375013975 0.4021304703099255 1.0 0.8079484821871163 16 P35610,Q9Y6B6,Q9BU23,P07237,P61916,Q8WTV0,O15118 7 +Slc transporter disorders 0.3390534054498194 0.8362410782915148 0.4030192932607861 1.0 0.8079484821871163 34 Q8TEM1,Q99567,Q12769,Q7Z3B4,Q8NFH4,Q8NFH5,Q9BTX1,P35613,P08195,P57740,O00400,P11166,Q9BW27,Q92621,Q8N1F7,Q9NRG9,P52948 17 +Myoclonic epilepsy of lafora 0.7244897959183685 0.8154139706045289 0.4148353901143191 1.0 0.816691119836678 2 P46976 1 +Diseases of mitotic cell cycle 0.4187380646984474 0.7957061469562101 0.4262028531852455 1.0 0.8237934868559571 12 Q96DE5,Q9UJX2 2 +Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.716919025674787 0.7854969845709986 0.4321622376098237 1.0 0.8283609048221587 2 P49327 1 +Cell surface interactions at the vascular wall 0.4019515220875962 0.7833226282875417 0.4334376784278275 1.0 0.8296549467967558 13 P62993,P53985,P54709,P35613,Q08722,P08195,Q92896 7 +Interactions of vpr with host cellular proteins 0.3331403266452739 0.779131601722381 0.4359021962214116 1.0 0.8332183059169996 34 P05141,Q7Z3B4,P12235,Q8NFH4,Q8NFH5,Q9BTX1,P12236,Q9BW27,Q8N1F7 9 +Amino acid transport across the plasma membrane 0.7116524028966437 0.7648437671417315 0.4443645822028719 1.0 0.8435602370939134 2 P08195 1 +Golgi to er retrograde transport 0.2939936557727191 0.7618623067775339 0.4461421887070462 1.0 0.8451888748608747 73 Q13409,Q92845,P49755,O75935,Q6NUQ1,O75396,P24390,Q9P2W9,Q9Y3B3,O14579,O15260,O43731,Q15363,Q12981,Q10471,Q10472,Q9UJW0,Q15042,Q9H0U4 19 +Beta oxidation of pristanoyl coa 0.6239041603030594 0.7525963586154445 0.4516925064806654 1.0 0.8460184599679419 4 O15254 1 +Diseases associated with glycosylation precursor biosynthesis 0.475651220583851 0.7439445143573321 0.4569100435196089 1.0 0.8460184599679419 8 P10619,Q86SQ9 2 +Potential therapeutics for sars 0.3331320355849005 0.7423386291995507 0.45788219271425 1.0 0.8460184599679419 32 Q99720,P21964,P49356 3 +Vasopressin regulates renal water homeostasis via aquaporins 0.6168266668181968 0.7243815951791799 0.4688314958771971 1.0 0.8590844708542801 4 P63218 1 +Glucagon signaling in metabolic regulation 0.6168266668181968 0.7243815951791799 0.4688314958771971 1.0 0.8590844708542801 4 P63218 1 +Sialic acid metabolism 0.6132404544347521 0.7101605887728831 0.4776045574560719 1.0 0.8643046836324256 4 P10619 1 +Regulation of tp53 activity through association with co factors 0.6935483870967756 0.6949456580578559 0.4870893577349406 1.0 0.8721699671153955 2 P31751 1 +Tp53 regulates transcription of death receptors and ligands 0.6935483870967754 0.6949456580578541 0.4870893577349418 1.0 0.8721699671153955 2 P49327 1 +Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0.6935483870967755 0.6949456580578535 0.4870893577349422 1.0 0.8721699671153955 2 P53611 1 +Sars cov 2 infection 0.3425689189996864 0.6778565834419671 0.4978626303700013 1.0 0.8818299292440129 24 P04844,Q8NEB9,P27824,Q10472,P46977 5 +G alpha s signalling events 0.4756097560975414 0.6727052921897895 0.5011348000815228 1.0 0.8845061222383964 6 P04899,Q9UBI6,Q9Y3E5,P63096,P63218 5 +Tp53 regulates transcription of cell death genes 0.6937767533750403 0.6660510135187071 0.5053784941404493 1.0 0.8880978732211771 3 P49327,P53611 2 +G1 s specific transcription 0.4241570876025189 0.6633657919099364 0.5070963090980942 1.0 0.8880978732211771 10 Q9Y619 1 +Recycling of eif2 gdp 0.4719995296908921 0.655292615684444 0.5122793742109759 1.0 0.8880978732211771 6 Q9NR50 1 +Senescence associated secretory phenotype sasp 0.3580294279410826 0.6491445008407895 0.5162449803818736 1.0 0.8880978732211771 18 Q9UJX3,P51812,Q96DE5,Q9UJX2 4 +Hemostasis 0.2950212556440005 0.6464882730852748 0.517963189297943 1.0 0.8880978732211771 112 O43852,Q92520,P07602,Q9NZJ7,Q8NCG7,Q9NTK5,Q9Y6I9,P16615,Q07021,Q08722,O94919,Q96JJ7,Q05655,P35613,Q9NUQ9,Q9UIJ7,P05067,P63218 18 +Signal amplification 0.4693473961766612 0.6425433926773365 0.5205204242498773 1.0 0.8880978732211771 6 P04899,Q9UBI6,P08754,P63096,P63218 5 +Fgfr1 mutant receptor activation 0.4559923446513683 0.6425433358263064 0.5205204611498939 1.0 0.8880978732211771 8 O95684,P62993,P42224,O94905,O95429 5 +Association of tric cct with target proteins during biosynthesis 0.3518044972827365 0.6223974143260435 0.5336805802304272 1.0 0.8901250164284832 19 P04062,Q99832,Q9Y2T2 3 +Mtorc1 mediated signalling 0.4044270919833913 0.62144051724086 0.534309820311399 1.0 0.8901250164284832 11 P62942 1 +Activation of ampk downstream of nmdars 0.4645879099579853 0.6197594682534915 0.5354161571310074 1.0 0.8901250164284832 6 P54646,P04350,Q9BUF5 3 +Cargo trafficking to the periciliary membrane 0.3475600911957813 0.6113975144160793 0.5409364477696743 1.0 0.8910813986774165 20 O43924,A6NIH7 2 +Activation of ppargc1a pgc 1alpha by phosphorylation 0.6711652402896654 0.6112305253721539 0.5410469774888038 1.0 0.8910813986774165 2 P54646 1 +Wax and plasmalogen biosynthesis 0.6776424102732974 0.6091267653730542 0.5424404178392663 1.0 0.8910813986774165 3 O00116,Q6IAN0 2 +Gastrin creb signalling pathway via pkc and mapk 0.487755550594974 0.5983151238146983 0.5496296871316675 1.0 0.8910813986774165 5 P51812 1 +Ripk1 mediated regulated necrosis 0.4126480914051885 0.5968762766563196 0.5505899871636046 1.0 0.8910813986774165 10 Q8WUM4,O75955,Q9UNE7,P49327,O00560 5 +Glucagon like peptide 1 glp1 regulates insulin secretion 0.4873520958308006 0.5965568802134056 0.5508032672808323 1.0 0.8910813986774165 5 P63218 1 +Adora2b mediated anti inflammatory cytokines production 0.4468997361477685 0.596219150843986 0.551028833597818 1.0 0.8910813986774165 8 P10644,P04899,Q9UBI6,Q9Y3E5,P08754,P63096,P63218 7 +Interleukin 12 family signaling 0.3225351891946806 0.591819739494778 0.5539713034738325 1.0 0.8910813986774165 28 P78417,P27824,Q13126,O14979,P07237,P52597 6 +Aflatoxin activation and detoxification 0.5822780874745432 0.5898682839974596 0.5552789588232667 1.0 0.8910813986774165 4 Q9UJ14 1 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.4855671425641465 0.5887905831617573 0.5560017636381875 1.0 0.8910813986774165 5 P10321,P04439 2 +Ca2 pathway 0.4844740916164044 0.584044927158419 0.5591900858112884 1.0 0.8910813986774165 5 P63218 1 +Linoleic acid la metabolism 0.6629361421988009 0.5813155778246151 0.5610277835248798 1.0 0.8910813986774165 2 O95864 1 +Mastl facilitates mitotic progression 0.4833607907742956 0.5792194424415896 0.5624411136205545 1.0 0.8910813986774165 5 P30153,O43768,P14635,P30154 4 +Activation of smo 0.6599736668860913 0.5706702768914768 0.5682231705791547 1.0 0.8946032862182561 2 P48729 1 +Apoptotic factor mediated response 0.5728461143253376 0.5542615370020713 0.5793998693327578 1.0 0.9016771014770276 4 Q9NR28 1 +Creb phosphorylation 0.6590713342822314 0.5453948716765417 0.585481966775536 1.0 0.9025731758918238 3 P51812 1 +Lysosome vesicle biogenesis 0.3545432504631117 0.5212647827142725 0.6021823305398539 1.0 0.9112050397328508 15 P05067 1 +Signaling by ptk6 0.374787983542635 0.5182614116589026 0.6042758924474521 1.0 0.9112050397328508 12 Q8IZL8,P18031,Q07666,O75525 4 +Free fatty acids regulate insulin secretion 0.644832126398948 0.5173575832610674 0.6049065637436326 1.0 0.9112050397328508 2 O95573 1 +Notch3 activation and transmission of signal to the nucleus 0.5621143027378629 0.5144445163723097 0.606941242365699 1.0 0.9112050397328508 4 Q92542 1 +Endosomal sorting complex required for transport escrt 0.3862660944205973 0.5132432500157897 0.6077811756047828 1.0 0.9112050397328508 11 Q9BRG1,O14964,Q9NZZ3,O43633,Q9H444,Q92783,Q9NP79,Q8WUX9,Q9H9H4,Q99816 10 +Constitutive signaling by akt1 e17k in cancer 0.4676309069009922 0.5119798903143732 0.6086650837670633 1.0 0.9112050397328508 5 P42345 1 +Class b 2 secretin family receptors 0.648840497179729 0.5112074635540931 0.6092057930580197 1.0 0.9112050397328508 3 P63218 1 +Platelet homeostasis 0.4143002682169187 0.5111753737118997 0.609228261008071 1.0 0.9112050397328508 9 P20020,P16615,P63218 3 +Signaling by cytosolic fgfr1 fusion mutants 0.4383651944627549 0.4968562291860313 0.6192904398938106 1.0 0.9119585613274244 6 O95684,P62993,P42224,Q9UBW7,P40763 5 +Transport of bile salts and organic acids metal ions and amine compounds 0.6440566348369963 0.4954663782203951 0.6202709494270715 1.0 0.9119585613274244 3 P53985,P35613 2 +Sars cov infections 0.2870630346913335 0.4870401953498972 0.6262298462879765 1.0 0.9158197328782895 56 P04844,Q99720,Q8NEB9,P27824,Q10472,P21964,P49356,P62942,P46977 9 +Mtor signalling 0.3493212396604496 0.486050621752453 0.6269312751875908 1.0 0.9158763449357828 15 P54619,P31751,P23588,Q9Y2Q5,Q15382,P42345,P54646,P62942 8 +Disorders of transmembrane transporters 0.27073933446975 0.480837619186668 0.6306319110842888 1.0 0.9174034748615656 75 Q9BUN8,P35613,P57740,Q9NRG9,Q9UBV2,P20618,Q92530,P49721,O00231,Q9UL46,O00400,P61289,Q9BW27,Q8N1F7,P25787,P28070,Q7Z3B4,Q8NFH4,Q8NFH5,P08195,O94905,P28072,Q12769,Q9BTX1,O75477,P11166 26 +Ra biosynthesis pathway 0.5449855435933253 0.4526169950054949 0.6508245588790096 1.0 0.9275052013668176 4 Q8NBN7 1 +Abacavir transport and metabolism 0.6250822909809022 0.4508370048569508 0.6521070286543618 1.0 0.9275052013668176 2 P08183 1 +Rsk activation 0.5444530619119143 0.4507318278185943 0.6521828401820866 1.0 0.9275052013668176 4 P51812 1 +Budding and maturation of hiv virion 0.3861386138613865 0.4471219892086582 0.6547869830670723 1.0 0.9275142553960966 10 O43633,Q9NZZ3,Q9H444,Q8WUM4,Q9NP79,Q8WUX9,Q9H9H4,Q96PU5,Q99816 9 +Signaling by pdgfr in disease 0.4510708401976943 0.4433555293109815 0.6575085966629348 1.0 0.9275142553960966 5 P42224,O43815,P62993,P40763 4 +Rhod gtpase cycle 0.3066319597866574 0.4385784273421286 0.6609670311399112 1.0 0.9292537507989392 26 O15173,Q14739 2 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.6192493159497316 0.4165876863488523 0.6769800176075105 1.0 0.935435872624886 3 Q9HCE1 1 +Dna damage recognition in gg ner 0.3386628550114984 0.4151857676817905 0.6780059167801342 1.0 0.935435872624886 15 Q9BT78,P41208 2 +Regulated necrosis 0.3369635033983492 0.404028571113446 0.68619170933283 1.0 0.9435328893367216 15 O43633,P04637,Q8WUM4,O75955,Q9UNE7,P49327,O00560 7 +Signaling by flt3 fusion proteins 0.5286561264822058 0.3959134306417953 0.6921688927260061 1.0 0.9458523597596984 4 Q14789,P62993,Q9UBW7 3 +Rhot1 gtpase cycle 0.6069782751810417 0.3932277265329727 0.6941512929687959 1.0 0.9458523597596984 2 Q8IXI2 1 +Acyl chain remodelling of ps 0.6050032916392273 0.3871538011705843 0.6986423496118748 1.0 0.9471884212910672 2 Q6P1A2 1 +Interleukin 12 signaling 0.3031371490430445 0.3820795077508921 0.7024023912652058 1.0 0.9488955080435136 25 P78417,Q13126,O14979,P07237,P52597 5 +Inla mediated entry of listeria monocytogenes into host cells 0.6000658327847284 0.3721587200176567 0.7097746788051329 1.0 0.9541912510784958 2 P35222 1 +Translation of sars cov 1 structural proteins 0.4094884644839681 0.3683144168519881 0.7126388038610478 1.0 0.9554584747158148 6 Q10472 1 +Activation of bad and translocation to mitochondria 0.3994063324538368 0.3636519577920738 0.7161179225813428 1.0 0.95625499239862 8 Q9Y3B8,P31751,P27348,P31946,P62258,P63104,Q04917 7 +Downregulation of erbb2 signaling 0.5177865612648219 0.359529772339899 0.7191988095345196 1.0 0.9584693874413752 4 Q16543,P31751,Q9UNE7 3 +Rhoc gtpase cycle 0.2930600552411334 0.3452929220265201 0.7298741672452258 1.0 0.9615972780168052 29 Q14739,P27105,P42167,Q13190 4 +Cyclin a b1 b2 associated events during g2 m transition 0.3562231759656609 0.3410571477855253 0.733060560278608 1.0 0.963929300004792 11 P53350,P06493,P24941,O95067,P63151,P30154,P14635,Q99640,O14980,P30153 10 +P75 ntr receptor mediated signalling 0.343554652348281 0.3311142109083655 0.7405582177827204 1.0 0.9700961677494973 12 Q9NQC3 1 +Regulation of localization of foxo transcription factors 0.3991430454845128 0.3245130311572599 0.7455496581804959 1.0 0.972138699056568 6 Q9Y3B8,P31751,P27348,P31946,P63104 5 +Molecules associated with elastic fibres 0.5799868334430498 0.3140982551410052 0.7534464147187998 1.0 0.978551842380893 2 P05556 1 +Elastic fibre formation 0.5799868334430498 0.3140982551410052 0.7534464147187998 1.0 0.978551842380893 2 P05556 1 +Depolymerisation of the nuclear lamina 0.3737019814668099 0.3047656727794631 0.7605446276507108 1.0 0.9795644691642892 9 P42167 1 +Ion homeostasis 0.3725591743724213 0.2992379144400464 0.7647585223147755 1.0 0.9804232633015024 9 P20020,P05023,P16615 3 +Rap1 signalling 0.570770243581305 0.2890990011899876 0.7725056179149876 1.0 0.9864417835608558 2 P31946 1 +Phenylalanine and tyrosine metabolism 0.4048060405703929 0.2671390019430756 0.7893621391889531 1.0 0.9932733680586372 5 O43708 1 +Mitotic g2 g2 m phases 0.2517593813398083 0.2640772805824321 0.7917203701281896 1.0 0.9942690175937162 87 Q13409,O75935,Q15154,P30154,Q9BSJ2,P41208,Q92530,P20618,P49721,P63208,P04350,O00231,P61289,O95684,P25787,P28070,Q99640,P28072,O94927,O14965,O43805,Q9H6D7,Q96CS2 23 +Ptk6 regulates cell cycle 0.5602369980250104 0.2618679078139382 0.793423282296164 1.0 0.9942690175937162 2 P11802 1 +Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0.5602369980250104 0.2618679078139382 0.793423282296164 1.0 0.9942690175937162 2 P04637 1 +Antigen activates b cell receptor bcr leading to generation of second messengers 0.5529953917050686 0.2439998799606896 0.8072309128866311 1.0 1.0 2 P62993 1 +Regulation of lipid metabolism by pparalpha 0.2981095850412318 0.2357712815396587 0.8136101539934841 1.0 1.0 19 P50416,P23786,Q15067,O75192,Q06520,P37268 6 +Regulation of kit signaling 0.5467412771560255 0.2291405024837284 0.8187597143608647 1.0 1.0 2 P62993 1 +Sars cov 1 infection 0.3119827366078744 0.2279606907656856 0.8196768001743187 1.0 1.0 14 Q10472,Q8NEB9 2 +Signaling by kit in disease 0.4670619235836686 0.2069196782134776 0.8360725880945168 1.0 1.0 4 P42224,P07947,P62993 3 +Signaling by erbb4 0.3680673193400731 0.2020285462062441 0.8398944076474435 1.0 1.0 6 Q92542,Q96J02 2 +Transport of connexons to the plasma membrane 0.4627799736495316 0.1955026547165582 0.844999459616917 1.0 1.0 4 P04350,P68371,Q9BUF5 3 +Gap junction assembly 0.4627799736495316 0.1955026547165582 0.844999459616917 1.0 1.0 4 P04350,P68371,Q9BUF5 3 +Regulation of hmox1 expression and activity 0.2609522026315204 0.193426856114988 0.8466246844286955 1.0 1.0 45 P25787,Q92530,P20618,P63208,P09601,P49721,P28070,O00231,Q05655,P61289,Q8TCT9,P28072 12 +Extracellular matrix organization 0.2737419003051191 0.1920191218598496 0.8477272270576202 1.0 1.0 30 P35613,Q08722,P07237,P05067,Q92542,P13674 6 +Ca dependent events 0.3598599566743189 0.1910375536820641 0.8484961713542352 1.0 1.0 7 Q05655,P52292 2 +Dna damage reversal 0.3818780889620992 0.1906393243985499 0.8488081787571193 1.0 1.0 5 Q8N3C0,Q9C0B1,Q9H1I8,Q8N9N2 4 +Laminin interactions 0.5327625946657812 0.1870370181581354 0.8516316087663476 1.0 1.0 3 P05556,P07942 2 +Akt phosphorylates targets in the cytosol 0.4594861660079123 0.1868901632583776 0.8517467518979605 1.0 1.0 4 O15111,P31751,Q96B36 3 +Pyruvate metabolism 0.2939967995348647 0.1759085908757387 0.860365756055173 1.0 1.0 17 P35613,O43708,P21796 3 +Activation of nmda receptors and postsynaptic events 0.2859246560987204 0.1665696542845756 0.8677086724433494 1.0 1.0 20 P51812,P07196,O14936,P04350,P10644,Q15418,Q9BUF5,P54646,P52292,Q14168 10 +Beta catenin phosphorylation cascade 0.3572841133816722 0.1632356713121919 0.8703328812136235 1.0 1.0 6 P48729,P49841,P30154,P35222,P30153 5 +Signaling by ctnnb1 phospho site mutants 0.3572841133816722 0.1632356713121919 0.8703328812136235 1.0 1.0 6 P48729,P49841,P30154,P35222,P30153 5 +Golgi cisternae pericentriolar stack reorganization 0.3127476882430566 0.1618704063049966 0.8714079077871018 1.0 1.0 12 P53350,P61019,Q9H8Y8,P06493,Q08379,P62820,O60763,O95067,P14635,P27361,Q9H0U4 11 +Interconversion of nucleotide di and triphosphates 0.2847217246890712 0.1587438793705283 0.873870665745812 1.0 1.0 20 Q9UIJ7 1 +Pre notch processing in the endoplasmic reticulum 0.5125082290980928 0.157485267777934 0.8748624176263449 1.0 1.0 2 Q04721 1 +Constitutive signaling by overexpressed erbb2 0.5176160684886311 0.1555469134988521 0.8763901723468517 1.0 1.0 3 Q16543,P62993 2 +Assembly of the hiv virion 0.5062541145490473 0.1461906794105598 0.8837708632650394 1.0 1.0 2 Q9H9H4 1 +Sumoylation of rna binding proteins 0.2672014484680061 0.1400250326970417 0.8886402120017585 1.0 1.0 30 Q8TEM1,P07910,Q99567,Q12769,Q7Z3B4,Q8NFH4,Q8NFH5,P61978,Q9BTX1,P57740,Q9BW27,Q8N1F7,Q9NRG9,P52948 14 +Tryptophan catabolism 0.500000000000002 0.135451839427054 0.8922546398125626 1.0 1.0 2 P08195 1 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.5051037207770844 0.1316950226359088 0.8952255225890027 1.0 1.0 3 P24941,P11802 2 +Sumoylation of ubiquitinylation proteins 0.2662707878359414 0.1223738079387438 0.9026029808245208 1.0 1.0 27 Q8TEM1,Q99567,Q12769,Q7Z3B4,Q8NFH4,Q8NFH5,Q9BTX1,P57740,Q9BW27,Q8N1F7,Q9NRG9,P52948 12 +Regulation of glucokinase by glucokinase regulatory protein 0.2662707878359414 0.1223738079387438 0.9026029808245208 1.0 1.0 27 Q8TEM1,Q99567,Q12769,Q7Z3B4,Q8NFH4,Q8NFH5,Q9BTX1,P57740,Q9BW27,Q8N1F7,Q9NRG9,P52948 12 +Sumoylation of sumoylation proteins 0.2662707878359414 0.1223738079387438 0.9026029808245208 1.0 1.0 27 Q8TEM1,Q99567,Q12769,Q7Z3B4,Q8NFH4,Q8NFH5,Q9BTX1,P57740,Q9BW27,Q8N1F7,Q9NRG9,P52948 12 +G beta gamma signalling through pi3kgamma 0.4291657745333102 0.1148488652826848 0.9085649163845436 1.0 1.0 4 P63218 1 +G protein mediated events 0.3117125460100373 0.1120338156331319 0.9107965943457308 1.0 1.0 11 Q05655,P52292 2 +Trna modification in the nucleus and cytosol 0.3296959557350249 0.1077278695908946 0.9142115614230923 1.0 1.0 9 Q9UBP6 1 +N glycan trimming in the er and calnexin calreticulin cycle 0.2885152987611203 0.0973221210475747 0.9224705893300188 1.0 1.0 14 Q9BUN8,P27824 2 +Dag and ip3 signaling 0.3359906461097395 0.096310314313151 0.9232741195322538 1.0 1.0 8 Q05655,P52292 2 +Phosphorylation of emi1 0.4830424761277535 0.0944635581900833 0.9247409293136968 1.0 1.0 3 P53350,P14635 2 +Carboxyterminal post translational modifications of tubulin 0.3479406919275207 0.0938588984301007 0.9252212439509512 1.0 1.0 5 Q9BVA1,P04350,P68371,Q9BUF5 4 +Ns1 mediated effects on host pathways 0.2585572996362786 0.0891720320725847 0.9289451919837596 1.0 1.0 33 Q7Z3B4,Q8NFH4,Q8NFH5,Q9BTX1,Q9BW27,Q8N1F7,P52292 7 +Interleukin 15 signaling 0.4667544437129713 0.0875020936722857 0.9302724213066214 1.0 1.0 2 P62993 1 +Interleukin 9 signaling 0.466754443712971 0.0875020936722851 0.9302724213066218 1.0 1.0 2 P42224 1 +Interleukin 21 signaling 0.466754443712971 0.0875020936722851 0.9302724213066218 1.0 1.0 2 P42224 1 +Adenylate cyclase inhibitory pathway 0.4751399407309701 0.0826203621132352 0.9341534100033808 1.0 1.0 3 P04899,P63096 2 +Interleukin 2 family signaling 0.4669081330260134 0.0711102772291376 0.9433099888332426 1.0 1.0 3 P42224,P62993 2 +Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.4669081330260134 0.0711102772291376 0.9433099888332426 1.0 1.0 3 P42224,P62993 2 +Death receptor signalling 0.2717847615616515 0.0639211823500342 0.9490329856920676 1.0 1.0 18 Q8TCT8,Q9NQC3 2 +Mitochondrial translation 0.2485572480738874 0.0585811700679761 0.9532857090309694 1.0 1.0 54 O60783,Q15070 2 +Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.322631043237199 0.0584403716736473 0.9533978577603346 1.0 1.0 7 Q15067,O95864 2 +Cdc42 gtpase cycle 0.2569868616785529 0.0552052507003361 0.9559749458629712 1.0 1.0 26 Q14739,P27105 2 +Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.4487981560750684 0.0486882486247162 0.961167741008742 1.0 1.0 3 O14734,P51659 2 +Rac3 gtpase cycle 0.2550591042817794 0.0481218139509827 0.9616191613241688 1.0 1.0 30 O15173,Q14739 2 +Peptide hormone metabolism 0.2747047181151021 0.0376534276558759 0.9699640089873474 1.0 1.0 15 Q96HE7,P67812 2 +Oncogene induced senescence 0.3121292023731086 0.0259772800338572 0.9792754602413454 1.0 1.0 6 Q00534,Q9HCE1,P04637,P11802,P27361 5 +The canonical retinoid cycle in rods twilight vision 0.384792626728113 0.0255258976600765 0.979635491869089 1.0 1.0 2 Q8TC12 1 +Signaling by fgfr1 in disease 0.3071597812003168 0.0224083388748704 0.9821222285627962 1.0 1.0 9 O95684,O95429,O94905 3 +Growth hormone receptor signaling 0.3120263591433293 0.0154435813766339 0.9876782946544524 1.0 1.0 5 P42224,P27361,P18031,P40763 4 +Beta oxidation of butanoyl coa to acetyl coa 0.4099206085891694 0.0130576311920747 0.9895818137251616 1.0 1.0 3 Q16836 1 +Traf6 mediated irf7 activation 0.2985516787360134 0.0104864741873727 0.9916331574938156 1.0 1.0 2 Q7Z434 1 +Traf3 dependent irf activation pathway 0.2985516787360134 0.0104864741873727 0.9916331574938156 1.0 1.0 2 Q7Z434 1 +Fbxw7 mutants and notch1 in cancer 0.2840684660961187 0.0099284200785941 0.9920783970497264 1.0 1.0 2 P63208 1 +Glycogen breakdown glycogenolysis 0.3027909817597189 0.0031674896642768 0.9974727131264124 1.0 1.0 6 P10253 1 +Ticam1 rip1 mediated ikk complex recruitment 0.3941389529140602 0.0028948773424696 0.9976902252891324 1.0 1.0 3 O15111,O14920 2 +Irak1 recruits ikk complex 0.3941389529140602 0.0028948773424696 0.9976902252891324 1.0 1.0 3 O15111,O14920 2 +Ikk complex recruitment mediated by rip1 0.3941389529140602 0.0028948773424696 0.9976902252891324 1.0 1.0 3 O15111,O14920 2 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..45db8caf9bf13fce2cd9f032d66c643eea8ba1c8 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pe", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate biosynthesis", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective b4galt1 causes b4galt1 cdg cdg 2d", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective lfng causes scdo3", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fertilization", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interaction with cumulus cells and the zona pellucida", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of tcf dependent signaling by dvl interacting proteins", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase 2 plateau phase", "Phase 3 rapid repolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retinoid cycle disease events", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 hd domain mutants in cancer", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc transporters"], "available_proteins": ["AAAS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG8", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APEH", "APEX1", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8A", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATG13", "ATG16L1", "ATG7", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCS1L", "BDH2", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRPF1", "BSG", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2orf49", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC22", "CCDC88A", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDS2", "CENPK", "CENPU", "CERS1", "CERS2", "CETN2", "CFL1", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST12", "CHST14", "CHTOP", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLINT1", "CLNS1A", "CLTA", "CLTB", "CLTC", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "COASY", "COG4", "COLEC12", "COLGALT1", "COMMD2", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ5", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2L", "CPD", "CPE", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRKL", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP2", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CWC15", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEGS1", "DEK", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSG2", "DSP", "DST", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFTUD2", "EHD1", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELOB", "ELP1", "ELP2", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERCC2", "ERCC6L", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM3C", "FAM49B", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNTB", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPB", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNL3", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPI", "GPKOW", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GUSB", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCS1", "HMGN1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILK", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "INPP4A", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS7", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISCU", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFAP3", "KIFC1", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRC8C", "LSM2", "LSM3", "LSM4", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "M6PR", "MAD1L1", "MAGED2", "MAGT1", "MAN1A2", "MAN2B1", "MANBA", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MAPRE1", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAVS", "MBD3", "MBIP", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED24", "MED25", "METAP1", "METAP2", "METTL1", "METTL14", "MFAP1", "MFN1", "MFN2", "MGST2", "MGST3", "MIA2", "MIA3", "MIB1", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL3", "MRPL37", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS14", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1C", "MYO6", "NAA35", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFL", "NEK9", "NELFB", "NELFCD", "NELFE", "NF1", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F2", "NRBP1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NT5C2", "NT5C3B", "NTHL1", "NUB1", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OSTM1", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H3", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCLAF", "PCM1", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX11A", "PEX14", "PEX16", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3C3", "PIK3R4", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "POFUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPIB", "PPID", "PPIH", "PPIL1", "PPIL4", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PWP2", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RBBP5", "RBBP6", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RNASET2", "RNF14", "RNF20", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP36", "RRP7A", "RRP8", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP18", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC15A4", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC37A4", "SLC3A2", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMDT1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX17", "STX18", "STX3", "STX5", "STX6", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SV2A", "SYMPK", "SYNE2", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARS", "TARS2", "TBC1D10A", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCP1", "TDRKH", "TECR", "TEX10", "TEX264", "TFAM", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM11", "TMEM59", "TMEM87A", "TMLHE", "TMOD3", "TMPO", "TMPO", "TMX3", "TNKS1BP1", "TNPO1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRMT10C", "TRMT11", "TRMT6", "TRMU", "TSFM", "TSG101", "TSN", "TSNAX", "TSR1", "TSTA3", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3C", "UBE4A", "UBQLN2", "UBR4", "UBTF", "UBXN1", "UCHL5", "UCK2", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", 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1.214909583878196 0.2447393771863318 7.583382097353882e-05 0.0607401038440192 0.0066572828402184 0.0002022933287296 0.0002481332774246 +Glycosaminoglycan degradation 4 6 2.4740347683011223 0.0133596694591642 3.407766990291262 5.864077669902913 0.1350713234786387 0.1703873780123549 1.3379225542760151 0.7043353086258667 1.932540087143412 0.2532951180616937 4.815836726362641e-05 1.0 1.0 0.0328731354880699 0.0001590313802548 +Sphingolipid metabolism in senescence 5 11 2.446569056133661 0.0144223166136654 4.349514563106796 11.679611650485436 1.1898351622318797 0.2087194733713789 1.8732078185138223 1.4259290429724831 1.4063103725171229 0.2533781048666968 0.001449857738388 1.0 0.1993869387044997 0.0173886328284286 0.0006386483653524 +Metapathway biotransformation phase i and ii 7 22 2.339806057197813 0.0192937560412571 5.674757281553398 21.74757281553398 1.0367643596879972 0.3247805075973627 2.26648088910968 1.8784337960788755 0.9302956939670612 0.2816826074355951 0.0017902790444148 1.0 0.0025924072114898 0.0005812813538685 0.0022883393024557 +Familial partial lipodystrophy fpld 1 7 2.2563326281449387 0.0240498074554393 2.7354368932038833 7.351941747572815 1.0487704575374006 0.2220749325398317 1.64741826657551 0.7567951823729889 1.2080189526980365 0.2461617416466816 0.1878361950417842 0.0963063052639835 0.0170518298819148 0.090818300458346 0.2722934148112151 +Degradation pathway of sphingolipids including diseases 3 6 2.213485010898126 0.0268642255040389 3.645631067961165 6.432038834951456 0.0687547082162972 0.1728701573933007 1.3368036576958324 0.5554170290527195 1.9109030412897592 0.2451148181788838 0.0002190493099042 1.0 1.0 0.0188064524051028 0.0005732271800539 +Alzheimers disease and mirna effects 15 84 2.1486719526972364 0.0316604135189881 19.78640776699029 84.62864077669903 0.8675405351918691 0.5019659822826982 9.06411947478317 6.212690980603589 1.0744065053186531 0.3869842050583563 0.0085973994513414 0.2479618444070664 0.012227438591947 0.0032939370021869 0.0170542901938563 +Proteoglycan biosynthesis 4 5 2.14406154366506 0.0320279558844553 1.966019417475728 4.298543689320389 1.0185999272660573 0.2724845511957944 1.255593573941796 1.5981475367005755 1.1753810774067486 0.2740057085210428 0.1085490453835639 1.0 0.1349531130589082 0.307957256786686 0.0049176108076387 +Sphingolipid pathway 5 8 2.135065512482066 0.0327556592101798 4.274271844660194 9.393203883495143 1.2258474538683668 0.1888473674707098 2.02173101931241 1.3620203536909472 1.3696572221543342 0.2416569853225122 0.001170591279029 1.0 0.191600110602388 0.0017432511761074 0.0004920431328091 +Overlap between signal transduction pathways contributing to lmna laminopathies 5 14 2.0770322003912622 0.0377985873568358 4.927184466019417 14.766990291262136 1.2077866030529698 0.2877996039599693 1.943257907759383 1.4611731122572065 0.935661776029738 0.2919054664837305 0.2419669128069012 0.1952735388158895 0.0693457394610891 0.2978006616879862 0.1740747384317906 +Sphingolipid metabolism overview 4 8 2.065943192362684 0.0388338438557818 4.0 7.951456310679611 1.305604070038762 0.1692072490812911 2.0060587839493125 1.5113078035984122 1.4254327231792938 0.2283290755268721 0.0032517223418875 1.0 0.1515272625734178 0.0074273483269255 0.0010145405611514 +Sphingolipid metabolism integrated pathway 4 8 2.065943192362684 0.0388338438557818 4.058252427184466 8.101941747572816 1.3056837288293504 0.1731905617886817 2.1182299017960826 1.603786816240382 1.4154175704443392 0.233855234687812 0.0049881070407295 1.0 0.1677870330809631 0.0102137155300364 0.0017585862412997 +Mitochondrial complex i assembly model oxphos system 9 25 2.065929661379705 0.0388351216611864 8.808252427184467 26.563106796116504 0.7827212026364002 0.3851038550171766 4.050605834390814 3.9632288075289823 1.2210776523685654 0.3331428769936953 0.0157915832911141 1.0 0.4072036678679048 0.1423397245441582 0.0002346698535802 +Oxidative phosphorylation 9 27 2.01260199550286 0.044156516878951 10.094660194174756 30.308252427184467 0.4493106572238387 0.4094278581483465 4.631390429635194 3.3340884045985604 1.35936739882113 0.3321380007425058 0.0006850070868271 0.0257535715284909 0.0135419734012732 0.0082403851981354 0.0001692953162957 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d35203880e786fa80fde20e43ebde8a09e8d6e1b --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 599, + "title": "Average number of proteins per term", + "value": 10.088480801335558 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5b0ab2205916a806820793ef7e5c224d411ce86d --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3de834828e552f01138519e6acfac95f02ebbf55 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,137 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Electron transport chain oxphos system in mitochondria 0.5795879014469966 3.4213051964620504 0.0006232135347514 0.3116248269456647 0.0960597245735085 47 Q9Y6N1,P05141,O96000,P12236,P14406,Q9UDW1,Q7KZN9,O75880,P00846,O14949,P24539,P12235,O75438,P21912,P13073,P03886,O75964,O43676,O14548,P56385,O75306,O95168 22 +Mitochondrial complex iv assembly 0.7456892304600063 2.9414767497846888 0.0032665136331921 0.8591196514787525 0.1503018401002884 13 Q9Y2R0,P14406,Q8N8Q8,Q7KZN9,Q96I36,P13073 6 +Mitochondrial complex iii assembly 0.8164398267085111 2.640668486644791 0.0082742639209045 0.9931046134339382 0.1768446677073902 9 Q9UDW1,O14949 2 +Nonalcoholic fatty liver disease 0.496496310470989 2.6290744330945697 0.0085617618756499 0.9942039345623936 0.1768446677073902 44 Q9P0J0,O14949,Q86Y39,O96000,Q96GC9,O43676,P14406,Q9UDW1,P13073 9 +Oxidation by cytochrome p450 0.916639209225696 2.5315976418493857 0.0113544199327866 0.9989301156566132 0.1821188689012213 5 O43169,P16435,Q6UW02,P00387 4 +Glycosaminoglycan degradation 0.8489407776348025 2.4740347683011223 0.0133596694591642 0.999682926805091 0.1905343334771279 6 P08236,P15586,P16278,P06865 4 +Sphingolipid metabolism in senescence 0.7132706923562178 2.446569056133661 0.0144223166136654 0.9998337254378796 0.1963401738996727 11 Q96G23,P16278,P04062,Q13510,Q06136 5 +Metapathway biotransformation phase i and ii 0.562602061674827 2.3398060571978134 0.0192937560412571 0.9999914527720972 0.2276213176251643 22 P78417,P07099,Q6UW02,Q8NCH0,P21964,O43708,Q7LGA3 7 +Familial partial lipodystrophy fpld 0.7796358252765783 2.2563326281449387 0.0240498074554393 0.9999995353084264 0.2478136766503345 7 O60725 1 +Degradation pathway of sphingolipids including diseases 0.7914471018382314 2.213485010898126 0.0268642255040389 0.9999999176071334 0.2554233504272914 6 P17900,P06280,P06865 3 +Alzheimers disease and mirna effects 0.3828917096922696 2.1486719526972364 0.0316604135189881 0.9999999957284624 0.274067793925554 84 Q9NQC3,P49721,P0DP25,Q8NEB9,P28070,P12235,P45880,Q96GC9,Q9Y277,P12236,P16615,P21796,Q92542,O95197,P05067 15 +Proteoglycan biosynthesis 0.8260296540362361 2.14406154366506 0.0320279558844553 0.9999999965972816 0.274067793925554 5 Q8TB61,Q9NX62,Q96L58,Q8NCH0 4 +Sphingolipid pathway 0.7471476659653992 2.135065512482066 0.0327556592101798 0.999999997831386 0.2763470403788414 8 Q96G23,O95470,P04062,Q13510,Q06136 5 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.5902203092012416 2.0770322003912622 0.0377985873568358 0.9999999999053047 0.2944587072791222 14 O60725,P50402,P55209,O75844,P42167 5 +Sphingolipid metabolism overview 0.7328937845682102 2.065943192362684 0.0388338438557818 0.9999999999503084 0.2944587072791222 8 O95470,Q06136,Q96G23,Q13510 4 +Sphingolipid metabolism integrated pathway 0.7328937845682102 2.065943192362684 0.0388338438557818 0.9999999999503084 0.2944587072791222 8 O95470,Q06136,Q96G23,Q13510 4 +Mitochondrial complex i assembly model oxphos system 0.5045816092993549 2.065929661379705 0.0388351216611864 0.9999999999503478 0.2944587072791222 25 Q9P0J0,O75306,P03886,Q9NPL8,Q96CU9,O96000,O75438,Q9BUB7,O43676 9 +Oxidative phosphorylation 0.4877526574582412 2.01260199550286 0.044156516878951 0.9999999999982148 0.3225579708596546 27 O75306,P03886,Q86Y39,P24539,O96000,O75438,O75964,P00846,P56385 9 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.5099656216832317 1.9498815189362184 0.0511902423630352 0.9999999999999786 0.3502459824727592 22 Q16850,Q14534,Q9BWD1,P35610,Q15800,P14324,Q14739,Q15392,P37268 9 +Alzheimers disease 0.3663391684340591 1.9476640917518024 0.0514551693783018 0.999999999999982 0.3502459824727592 82 Q9NQC3,P49721,P0DP25,Q8NEB9,P28070,P12235,P45880,Q9Y277,P12236,P16615,P21796,Q92542,O95197,P05067 14 +Adipogenesis 0.5735167621999748 1.9175577329018367 0.0551671138950995 0.9999999999999982 0.371293272170389 13 Q9NZ45 1 +Ccl18 signaling pathway 0.61280017567168 1.8828695851976232 0.0597180439487567 1.0 0.3779250575849505 11 Q86UE4,Q96GC9 2 +Kennedy pathway from sphingolipids 0.755845874228289 1.8322901210975848 0.0669082081319447 1.0 0.3918327558012702 5 O95470,Q9UG56 2 +Hostpathogen interaction of human coronaviruses autophagy 0.7096751126251208 1.82915148521247 0.0673769179424554 1.0 0.3918327558012702 6 Q676U5 1 +Ferroptosis 0.4698147293880693 1.734814756333865 0.0827736216275889 1.0 0.4361955599809758 24 Q9NZ45,P09601,Q9Y277,P45880 4 +Progeriaassociated lipodystrophy 0.6352170461114937 1.7229242404359788 0.0849022261094292 1.0 0.4361955599809758 9 O60725 1 +Glycerophospholipid biosynthetic pathway 0.6609498680738661 1.7087159475694385 0.087503578605778 1.0 0.4404591897887484 8 Q9BTU6,Q86UL3,O00116,O14735,Q8WUK0,O95674,P48651 7 +Nanoparticle triggered autophagic cell death 0.7184061404939281 1.6621285762922824 0.0964869969764978 1.0 0.458213555720125 5 Q676U5 1 +Influence of laminopathies on wnt signaling 0.5930499817950371 1.6516895357186538 0.0985978569637955 1.0 0.458213555720125 10 O60725 1 +Copper homeostasis 0.6692362805779242 1.6334012016414072 0.1023846444843017 1.0 0.4611158048578702 6 P05067,Q9Y6N1 2 +Vitamin d receptor pathway 0.5452785222902752 1.6033574827170949 0.1088557522463979 1.0 0.479445555849944 12 P20020,P49427,P04080,Q5VV42,Q06520,Q96KA5,Q92604 7 +Cholesterol biosynthesis with skeletal dysplasias 0.661176725853137 1.5939800010776632 0.1109405142869426 1.0 0.4801495688753965 6 Q14739,Q15392 2 +Calcium regulation in cardiac cells 0.4414202619240591 1.5526748121874785 0.1205008427138005 1.0 0.4897587908214251 25 P20020,P0DP25,P16615,P10644,Q05655,Q9P246,P62942,P63218 8 +Metabolism of spingolipids in er and golgi apparatus 0.8132411067193791 1.5382018638547552 0.1239992654181727 1.0 0.4897587908214251 4 Q10472,Q06136,O95470 3 +Statin inhibition of cholesterol production 0.8086297760210939 1.5190072629701503 0.1287606678138506 1.0 0.4955318918751076 4 Q8WTV0,Q14534,P37268 3 +Omega9 fatty acid synthesis 0.6456822676334835 1.5178453845768356 0.1290533808556104 1.0 0.4955318918751076 6 P33121,P49327,O95573,O95864,O00767 5 +Omega3 omega6 fatty acid synthesis 0.645682267633475 1.517845384576795 0.1290533808556206 1.0 0.4955318918751076 6 P33121,O15254,Q15067,O95573,O95864 5 +Inclusion body myositis 0.8854509545753665 1.4863814178097643 0.1371782620863353 1.0 0.5103712980727632 2 P05067 1 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.9005994431300974 1.4581413554355271 0.1448015843539338 1.0 0.5225069218554601 3 P09601 1 +Myometrial relaxation and contraction pathways 0.45394826342116 1.4386347875602106 0.1502540246673849 1.0 0.5325571643536305 20 P16615,P0DP25,P78417,Q05655 4 +Spinal cord injury 0.4356303434983856 1.297482941141774 0.1944650709004951 1.0 0.6262611691903043 20 Q08722,Q9NQC3,P62942,P08670 4 +Vitamin d metabolism 0.8530301034989038 1.2715546452177948 0.2035314001374586 1.0 0.6297590800848714 3 P04062 1 +Angiopoietinlike protein 8 regulatory pathway 0.402243854167601 1.268653402000337 0.2045647089449052 1.0 0.6297590800848714 26 P51812,P13807,Q8NEB9,P31751,O75955,P49327,P18031,Q15418,Q15382,O14654,P42345,P11166,P54646,O00767 14 +Regulation of apoptosis by parathyroid hormonerelated protein 0.745214885593639 1.2538116537956658 0.2099104723404958 1.0 0.6350321865250355 4 Q9BXK5 1 +Small cell lung cancer 0.50643776824034 1.2474347786850977 0.2122381209355961 1.0 0.6356531722021104 11 O15111,P07942,P04637,P11802,P63208,P05556,P31751,P11047,O14920,P24941 10 +Nanomaterial induced apoptosis 0.7318840579710096 1.197957009053224 0.2309337539856919 1.0 0.6540492879110953 4 O43464,O95831,Q9NR28 3 +Osteoblast differentiation and related diseases 0.5109853765968358 1.1751649297167852 0.23992873797489 1.0 0.6590556451958268 10 Q8NEB9 1 +Cholesterol biosynthesis pathway 0.4921749837491899 1.1598965753162729 0.246090917241553 1.0 0.6635345951443776 11 Q14534,P14324,Q15800,Q16850 4 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.6094587188622109 1.1560703766325997 0.2476523717897572 1.0 0.6635345951443776 5 Q15118,P42345,Q15382 3 +Urea cycle and related diseases 0.7982225148123478 1.117249329902292 0.2638877338963585 1.0 0.6899306131141798 2 Q9Y619 1 +Eicosanoid synthesis 0.8088656762337756 1.099059472394999 0.2717421258594066 1.0 0.6928056634938087 3 Q9NP80 1 +Praderwilli and angelman syndrome 0.5834820906083162 1.0345694227833326 0.3008700400217901 1.0 0.732606316963627 5 Q15154,P04637,P11802 3 +Glycerolipids and glycerophospholipids 0.5259266335623446 0.9869712228508482 0.3236567462873536 1.0 0.7678086954777034 7 Q86UL3,O14735,Q9UG56,Q9HBU6,P48651 5 +Camkk2 pathway 0.5096175345624344 0.9216714241988874 0.3566999903465861 1.0 0.7855268169764894 8 P09601,O76024 2 +Triacylglyceride synthesis 0.6600790513834064 0.8993604770859351 0.3684606838613935 1.0 0.7939973202749508 4 O00116,Q9NUQ2,Q99943 3 +Allograft rejection 0.4774643713156684 0.8553884842505661 0.3923361166467543 1.0 0.8131810860602277 9 P10321,P49327,P08670,P04439 4 +Nephrotic syndrome 0.4415002454340051 0.847525698089814 0.3967021695138122 1.0 0.8136856071122627 11 Q9BT22,O75844 2 +Apoptosis modulation by hsp70 0.7314022383146819 0.8429492735142147 0.399256814402928 1.0 0.8136856071122627 2 O95831 1 +Familial hyperlipidemia type 4 0.731402238314671 0.8429492735141714 0.3992568144029522 1.0 0.8136856071122627 2 Q9UBV2 1 +Nuclear receptors in lipid metabolism and toxicity 0.7307439104674138 0.8403182465829174 0.4007299734526168 1.0 0.8136856071122627 2 P28288 1 +Drug induction of bile acid pathway 0.7307439104674138 0.8403182465829174 0.4007299734526168 1.0 0.8136856071122627 2 Q06520 1 +Liver x receptor pathway 0.716919025674787 0.7854969845709986 0.4321622376098237 1.0 0.8459646415957008 2 P49327 1 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.7116524028966437 0.7648437671417315 0.4443645822028719 1.0 0.8614057758560526 2 P08195 1 +Mecp2 and associated rett syndrome 0.3678059001418787 0.7439985230806704 0.4568773686125928 1.0 0.8739821010583702 19 P67809,Q08211,P31943,P52597,Q99640,Q03518,P35637 7 +Thermogenesis 0.3444957328718949 0.727260291738445 0.4670665181500921 1.0 0.8794777480015594 25 P51812,P23786,Q9UKU0,Q969G3,Q15418,Q15382 6 +Photodynamic therapyinduced ap1 survival signaling 0.6129186428276014 0.7088870520650091 0.4783945706972698 1.0 0.8794777480015594 4 Q07820,P49327 2 +Lncrnamediated mechanisms of therapeutic resistance 0.6935483870967754 0.6949456580578541 0.4870893577349418 1.0 0.8794777480015594 2 P08183 1 +Microrna network associated with chronic lymphocytic leukemia 0.6935483870967569 0.6949456580577841 0.4870893577349857 1.0 0.8794777480015594 2 Q07820 1 +Congenital generalized lipodystrophy cgl 0.6932192231731416 0.6936917166727542 0.48787556179047 1.0 0.8794777480015594 2 P31751 1 +Gastric cancer network 2 0.3791376535991789 0.6903349376132766 0.4899835817122209 1.0 0.8794777480015594 15 Q14739,Q86UE4 2 +Caloric restriction and aging 0.6937767533750318 0.6660510135186772 0.5053784941404684 1.0 0.8794777480015594 3 P43490,P42345 2 +Glycosylation and related congenital defects 0.4216481491250733 0.6488128067420563 0.5164593786074605 1.0 0.881168046047916 10 Q9BT22,P15291,Q9H0U3,Q9BV10 4 +7oxoc and 7betahc pathways 0.4357757306387727 0.6261591379601337 0.5312105661031121 1.0 0.8817614085439555 9 P61916,O14734,O15118 3 +Joubert syndrome 0.3629417694888155 0.6102770525874806 0.5416782953074555 1.0 0.8913881837614446 16 O43924,Q10713,P41208 3 +Neuroinflammation 0.5775713660597455 0.5720317630055184 0.5673004562220179 1.0 0.9085908376390072 4 P42345 1 +Cellular proteostasis 0.5737812911725955 0.557767292759017 0.5770032996919809 1.0 0.9152078393884404 4 Q9UHV9,P61758,O15212 3 +Sting pathway in kawasakilike disease and covid19 0.6616978359006389 0.554281696715068 0.5793860746068082 1.0 0.9152078393884404 3 O00221 1 +Canonical nfkb pathway 0.6616978359006389 0.554281696715068 0.5793860746068082 1.0 0.9152078393884404 3 O00221 1 +Apoptosis 0.4220851407568488 0.552509544332162 0.5805992971078586 1.0 0.9152078393884404 9 P04637,Q07820,O00221,P49327,Q9NR28 5 +P53 transcriptional gene network 0.4364378687639103 0.5329452125709556 0.5940715064065745 1.0 0.9188711054873296 7 P04066,Q9NQ88,P49327 3 +Fluoropyrimidine activity 0.376673086711422 0.5299025370075128 0.5961795070820108 1.0 0.9188711054873296 12 P00374,Q92820,Q99808 3 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.37292565809225 0.5067926190040397 0.6123003357821202 1.0 0.9209068752314994 12 O75718,P07237,O15460,Q5JRA6,P13674 5 +Sars coronavirus and innate immunity 0.6395655036208046 0.4992690325000833 0.6175898680976366 1.0 0.9209068752314994 2 Q7Z434 1 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0.9975422849290972 4 Q9BWD1 1 +Cannabinoid receptor signaling 0.4985352468064413 0.2980712996265958 0.7656487460515453 1.0 1.0 4 Q8NCG7 1 +Hostpathogen interaction of human coronaviruses mapk signaling 0.3880437221922881 0.2790943945188883 0.780172384811423 1.0 1.0 6 P51812 1 +Head and neck squamous cell carcinoma 0.3207380489876019 0.2633118362522993 0.7923102374913875 1.0 1.0 13 P04637,P11802,P31751,Q15382,P42345,P62942 6 +15q112 copy number variation syndrome 0.4853956399232408 0.2585240586329173 0.7960024837345103 1.0 1.0 4 Q9BSJ2,Q06787 2 +Nitric oxide metabolism in cystic fibrosis 0.4825428194993477 0.250212992513792 0.8024226381922961 1.0 1.0 4 O60678,Q99873,Q86X55 3 +Zinc homeostasis 0.5503620803159992 0.2376781459614154 0.8121307350005764 1.0 1.0 2 Q8NEW0 1 +Phosphoinositides metabolism 0.3701659118330758 0.2323554529930815 0.8162619454721118 1.0 1.0 8 Q8NEB9 1 +Type ii interferon signaling ifng 0.3653762778359488 0.2129625430557018 0.8313561787921468 1.0 1.0 7 Q05655 1 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P42224,O15111,Q7Z434,O14920 4 +Aryl hydrocarbon receptor pathway wp2873 0.5149818900230465 0.1503617351563412 0.8804792289235006 1.0 1.0 3 Q16543,P07900 2 +Sarscov2 b117 variant antagonises innate immune activation 0.5016458196181719 0.1382241078896415 0.8900633026320213 1.0 1.0 2 Q7Z434 1 +Ppar signaling pathway 0.2865989642925545 0.1314156428682195 0.8954465147592507 1.0 1.0 17 P50416,O15254,P23786,Q9UKU0,Q15067 5 +Gdnfret signaling axis 0.4347826086956499 0.1271827782364892 0.8987957356608987 1.0 1.0 4 Q12948,P35222,O94813 3 +Nad metabolism 0.50201106346378 0.1261042670412769 0.899649389827716 1.0 1.0 3 P43490 1 +Nad biosynthetic pathways 0.50201106346378 0.1261042670412769 0.899649389827716 1.0 1.0 3 P43490 1 +Genes related to primary cilium development based on crispr 0.2937871777924578 0.1253344898871946 0.9002587484740903 1.0 1.0 14 O95684,Q6UVJ0,Q9C0F1,Q92845,Q9ULC3,Q86YT6,Q9Y496,Q7Z392,Q10713,P63167,Q9BW83,Q86SX3,A0AVF1 13 +Iron metabolism in placenta 0.4904542462146169 0.120125190057601 0.90438397809494 1.0 1.0 2 P02786 1 +Type ii diabetes mellitus 0.3571278588774043 0.1179694946944953 0.9060918287745224 1.0 1.0 5 Q05655 1 +Sarscov2 and covid19 pathway 0.4909811329674756 0.1071517029413021 0.9146686302204856 1.0 1.0 3 Q8WTV0 1 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.3361932782857983 0.0970502904068408 0.9226864569378426 1.0 1.0 8 P42345,P49770 2 +Mitochondrial long chain fatty acid betaoxidation 0.2902588886415566 0.0958445217218099 0.9236440568779564 1.0 1.0 13 P23786 1 +Mammary gland development pathway involution stage 4 of 4 0.4667544437129713 0.0875020936722857 0.9302724213066214 1.0 1.0 2 P04637 1 +Leptininsulin signaling overlap 0.4667544437129711 0.0875020936722854 0.9302724213066216 1.0 1.0 2 O14654 1 +Purinergic signaling 0.4751399407309701 0.0826203621132352 0.9341534100033808 1.0 1.0 3 P04899,P63096 2 +Sulfation biotransformation reaction 0.4107378129117307 0.0777146509065733 0.9380550396160678 1.0 1.0 4 Q06520,P11413,O43252 3 +Transcription factors regulate mirnas related to cardiac hypertrophy 0.4669081330260186 0.0711102772291446 0.943309988833237 1.0 1.0 3 Q9P2K5,P31751 2 +Preimplantation embryo 0.3239232152867448 0.0625508195234141 0.950124193010917 1.0 1.0 7 P05023,Q99729 2 +Srebf and mir33 in cholesterol and lipid homeostasis 0.4004421325712367 0.0592112963483711 0.9527838122454102 1.0 1.0 4 P49327,P42345 2 +Pi3kaktmtor vitd3 signaling 0.3321252059308104 0.0561813092081423 0.9551973707340627 1.0 1.0 5 P00338,P54646,P49841,P42345 4 +Mitochondrial immune response to sarscov2 0.3134279115803522 0.0448976409694829 0.9641888971838664 1.0 1.0 9 Q99623,Q7Z434,P35232,Q9Y276,O94826,Q9Y6M9,Q9H845,Q9BQ95 8 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.3124381392279919 0.041280474214955 0.9670722991194024 1.0 1.0 9 O15111,P63000,Q13547,P35222,P31751,P49841,O14920,P27361 8 +Oxysterols derived from cholesterol 0.3151994724695011 0.0355439530214136 0.9716459990579462 1.0 1.0 7 O14734,Q9UBM7,O00154,Q15125,P22307,Q9Y305 6 +Glycogen synthesis and degradation 0.2670681560924673 0.0227392208925318 0.9818582901675031 1.0 1.0 17 P52789,P0DP25 2 +Ciliopathies 0.2751314078491871 0.0226248210757999 0.9819495445379592 1.0 1.0 13 Q15555,O43924,Q10713 3 +Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.3123350923482889 0.0161776250159263 0.9870926857792656 1.0 1.0 8 O14964,Q8WUM4,P51148,P31943,P20339,P27361,P61020 7 +Robo4 and vegf signaling pathways crosstalk 0.3446346280447689 0.0149879740357668 0.988041774635517 1.0 1.0 2 O94813 1 +Vasopressinregulated water reabsorption 0.269199520092954 0.0107371727619529 0.991433140234635 1.0 1.0 15 Q15907,Q9UJW0 2 +Amyotrophic lateral sclerosis als 0.301632836944559 0.003418608311327 0.997272350521914 1.0 1.0 9 Q9BUN8,O96008,P07196,P07197 4 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..20de653613186277a28bc83e5891c2439404c8a0 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna for targeting cancer growth and vascularization in glioblastoma", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Srf and mirs in smooth muscle differentiation and proliferation", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Tamoxifen metabolism", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCD3", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG8", "AMOT", "ANAPC1", "ANAPC5", "ANAPC7", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APEX1", "APMAP", "APP", "APPL1", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG13", "ATG16L1", "ATG7", "ATG9A", "ATIC", "ATP11C", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AURKA", "B3GALT6", "B4GALT1", "BAG2", "BAG3", "BAG4", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAS3", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BLM", "BLVRA", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "C1QBP", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPZB", "CARM1", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCDC88A", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD47", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CEP170", "CEP44", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CHUK", "CIP2A", "CISD1", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLPTM1L", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT10", "CNOT9", "CNP", "COA3", "COASY", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEGS1", "DEK", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DPF2", "DPM1", "DPYSL2", "DSC2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECSIT", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOB", "EMD", "EML4", "ENAH", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPRS", "EPS15", "ERCC2", "ESD", "ETF1", "ETFA", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC2", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FKBP10", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAPDH", "GART", "GBA", "GBE1", "GCC2", "GCDH", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GIGYF2", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GMPPB", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPI", "GPS1", "GRB2", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2F2", "GTF2I", "GTPBP4", "GUSB", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF2", "ILK", "IMP3", "IMPAD1", "IMPDH2", "INF2", "INPP4A", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITCH", "ITGB1", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFAP3", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEMD3", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRC59", "LRRC8C", "LRWD1", "LSM2", "LSM4", "LSM7", "LSS", "LTA4H", "LUC7L", "MACF1", "MAD1L1", "MAGT1", "MAP1B", "MAP2K1", "MAP4", "MAPK1", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAVS", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MEPCE", "MFAP1", "MFN2", "MGST2", "MGST3", "MIA3", "MIB1", "MIF", "MKI67", "MMAB", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPG", "MPI", "MPP1", "MPP2", "MPST", "MRE11", "MRPL19", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTR", "MUT", "MYBBP1A", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAPG", "NCBP1", "NCBP2", "NCDN", "NCK2", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NF1", "NFKBIE", "NIPBL", "NKRF", "NME1", "NME2", "NONO", "NOP2", "NOTCH2", "NPC1", "NPC2", "NR2F2", "NSDHL", "NSF", "NTHL1", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "ORC3", "OSBPL3", "OSTM1", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDS5A", "PDS5B", "PDSS1", "PEBP1", "PECR", "PELO", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PIGT", "PIK3C2A", "PIK3C3", "PIK3R4", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMPCA", "PMVK", "PNKP", "PNP", "PNPLA8", "PNPO", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PURA", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB23", "RAB2A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RBP1", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RIF1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SASS6", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC23A", "SEC24A", "SEC24C", "SEC31A", "SEL1L", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SEZ6L2", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SFSWAP", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35B2", "SLC3A2", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SNAP23", "SNAP29", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPEN", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSNA1", "SSR4", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIM2", "STIP1", "STK4", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STX3", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAB1", "TACO1", "TALDO1", "TAP1", "TARDBP", "TBC1D10A", "TBC1D4", "TBCA", "TBL2", "TCP1", "TECR", "TEDC1", "TELO2", "TFAM", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMED10", "TMEM165", "TMEM43", "TMEM70", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT2A", "TSG101", "TTC19", "TTC26", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TXNDC5", "TXNRD1", "TYMS", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2G2", "UBE2L3", "UBE2N", "UBE2T", "UBR5", "UBTF", "UCHL5", "UCK2", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNG", "UPF1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP10", "USP5", "USP7", "USP9X", "UTRN", "VAPA", "VAPB", "VARS1", "VASP", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS16", "VPS18", "VPS33A", "VPS37B", "WAPL", "WARS", "WDHD1", "WDR1", "WDR5", "WDR74", "WFS1", "WIPI2", "WNK1", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZMPSTE24", "ZNF281", "ZYX"], "leading_proteins": ["ABCB1", "ABCD3", "ACAD9", "ACAT2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACSL1", "ACSL3", "ACSL6", "AGPAT1", "AGPAT5", "AGPS", "AIFM1", "AKT2", "ALG1", "ALG12", "APP", "ASAH1", "ATG16L1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5F1", "ATP5I", "ATP5L", "ATP6", "B3GALT6", "B4GALT1", "BCL2L13", "BCS1L", "CALM3", "CARM1", "CD47", "CDC34", "CDC37", "CDIPT", "CDK2", "CDK4", "CDKAL1", "CDS2", "CEP44", "CERS2", "CETN2", "CHST14", "CHUK", "CISD1", "CLPTM1L", "COA3", "COMT", "COX11", "COX14", "COX15", "COX18", "COX4I1", "COX7A2", "COX7A2L", "CPT1A", "CPT2", "CRTAP", "CSTB", "CTNNB1", "CYB5B", "CYB5R3", "CYP20A1", "CYP51A1", "DAGLB", "DCTN4", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHX9", "DIABLO", "DYNLL1", "EBP", "ECE1", "ECSIT", "EIF2B2", "EMD", "EPHX1", "ETFDH", "ETNK1", "FADS2", "FASN", "FDFT1", "FDPS", "FGFR1OP", "FKBP1A", "FLOT1", "FMR1", "FOXC1", "FOXRED1", "FUCA1", "FUS", "G6PD", "GALNT1", "GBA", "GGH", "GLA", "GLB1", "GM2A", "GNAI1", "GNAI2", "GNG5", "GNS", "GPAT4", "GSK3B", "GSTO1", "GSTZ1", "GUSB", "GYS1", "HDAC1", "HEXA", "HGS", "HK2", "HLA-A", "HLA-C", "HMOX1", "HNRNPAB", "HNRNPF", "HNRNPH1", "HS2ST1", "HSP90AA1", "HTRA2", "ICMT", "IFT27", "IKBKB", "IMPAD1", "IRS4", "ITGB1", "KDM1B", "KDSR", "KIF3A", "KIFAP3", "LAMB1", "LAMC1", "LBR", "LDHA", "LPGAT1", "MAGT1", "MAPK3", "MAPRE2", "MAVS", "MCL1", "MIA3", "MIB1", "MSMO1", "MTDH", "MTOR", "MYEF2", "NAMPT", "NAP1L1", "NCSTN", "ND1", "NDUFA11", "NDUFA13", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEFL", "NEFM", "NFKBIE", "NOTCH2", "NPC1", "NPC2", "P4HA1", "P4HA2", "P4HB", "PAPSS1", "PCM1", "PDCD6IP", "PDE6D", "PDK1", "PDSS1", "PFDN2", "PFDN6", "PHB", "PHB2", "PI4K2A", "PIK3C3", "PISD", "PKMYT1", "PMPCA", "PNPLA8", "POR", "PRKAA2", "PRKAR1A", "PRKCD", "PRMT1", "PRMT3", "PSMB2", "PSMB4", "PTDSS1", "PTPMT1", "PTPN1", "RAB11B", "RAB23", "RAB5A", "RAB5B", "RAB5C", "RAC1", "RHEB", "RPS6KA1", "RPS6KA3", "RTN3", "RTN4", "SASS6", "SCARB1", "SCD", "SCO1", "SCP2", "SDHB", "SEL1L", "SGPL1", "SKP1", "SLC25A15", "SLC25A4", "SLC25A5", "SLC25A6", "SLC29A1", "SLC2A1", "SLC30A7", "SLC35B2", "SLC3A2", "SLIT2", "SMARCE1", "SOAT1", "SQLE", "STAT1", "STIM2", "STK4", "SULT2A1", "SUN1", "TAP1", "TEDC1", "TFRC", "TIGAR", "TIMMDC1", "TMEM70", "TMPO", "TOMM40", "TOMM70", "TP53", "TRAPPC11", "TTC26", "TUBGCP2", "ULK3", "UQCR10", "UQCRQ", "VBP1", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "WFS1", "YBX1", "ZMPSTE24"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..16394af118812334afd67d06e09a1af065a2166f --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "er", "1": "mitochondria"} \ No newline at end of file diff --git a/opencell_localization/advanced/plot_0.png b/opencell_localization/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ee4c3501fd80e2ee442687af1b9dba9cee8ea596 --- /dev/null +++ b/opencell_localization/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a9b3384b4a97ce07da1d52c77091b31216f3ccab755320754f5780c5f1907361 +size 191583 diff --git a/opencell_localization/advanced/plot_1.png b/opencell_localization/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..86730122d124aafb51c46924170a44fcf856ff80 --- /dev/null +++ b/opencell_localization/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6611c94f17a9a644d9a0762c4a2d4b8146ea2edfe6f53e7bd39466f1030cc3e4 +size 175134 diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..cecc8a12ee96f2cc1a057df10e0db6d39c5155c3 --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "er", "1": "mitochondria", "2": "golgi", "3": "vesicles"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..4b731d068b287ba0576aa900365725e7df665ec3 --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:df7730a954025fe5e9751d28fc3766c1961011e6b97f354bffa270dc90ccacfc +size 135944 diff --git a/opencell_localization/basic/plot_1.png b/opencell_localization/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..1de339e5d48b1bec87b91706df875a39ead3ec9c --- /dev/null +++ b/opencell_localization/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:72166c58f55ae4a4a7e78cf430d62d8404e7af272ee2e79b517f7a087ba78f3e +size 132602 diff --git a/opencell_localization/basic/plot_2.png b/opencell_localization/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..2d4defb40a712670d683e60344dfa3a08769ff3e --- /dev/null +++ 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sha256:0340360cb26b849ec6307d276f35e277e37f4afcac302c1a122bcaff3f8f691b +size 69691 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6af7a4f395c9871e40f8364d11e12aed1b5a724b --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +er 45 95 4.305827471482126 1.6636268330039172e-05 29.17233009708738 87.61893203883496 1.3358083950399515 0.3757472714196316 13.465054065187209 8.223393744963309 2.0429537263872786 0.4010648005920765 1.291174947881705e-16 0.4978494903048275 0.011785471900189 2.4184254940866785e-11 1.4780407292722944e-18 +mitochondria 8 11 2.4116210968285303 0.0158817768079382 4.441747572815534 10.567961165048544 1.1937677940164793 0.2159787381789819 2.254231157409949 0.7391563798220593 1.4011905974754153 0.2980089661914649 7.583382097353882e-05 0.0607401038440192 0.0066572828402184 0.0002022933287296 0.0002481332774246 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bc6f659aba9ff4e1a81d2fb4994945fcf1132521 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 95.58823529411765 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bdf271e09e1f2161a6b4b609973a7083ebadf315 --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3975cafb76bf05fdd03f8ca530b771f76bdc92e2 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +er 0.5730457630301458 4.305827471482126 1.6636268330039172e-05 0.0002827789246437 0.0002828165616106 95 Q16850,Q6NUK4,P49755,Q96N66,P27824,O75396,Q15392,Q06136,Q969V3,Q9NPA0,Q9NR31,Q8NF37,Q96A33,O95470,P51572,Q9P2W9,O95674,O00264,O00400,P61026,O15269,Q15006,Q9P246,Q13190,P61019,Q9NQC3,Q07065,Q00765,Q15363,Q96GC9,P00387,Q12981,Q9NTJ5,Q99640,Q9Y487,Q8N4V1,P46977,Q9Y5M8,P04844,Q969Q5,Q8NHH9,O15173,Q14739,Q9H6H4,O96005 45 +mitochondria 0.7068433989893513 2.4116210968285303 0.0158817768079382 0.2382654485388436 0.0899967352449833 11 Q9NVH1,Q969Q5,P45880,Q9Y277,Q8IWA4,P21796,Q15388,Q9NR31 8 +golgi 0.4028249877508987 1.935856275060188 0.0528853062874075 0.6029513126130714 0.1798100413771855 63 O15258,Q15907,O75122,Q8IZA0,Q15904,P49755,Q8WVM8,Q9Y6B6,O43826,P40616,Q9NR31,Q9H8Y8,P61026,O14579,Q9UM00,Q13190,P61019,Q8NBN3,O14653,O15127,Q9NTJ5,Q9Y487,Q5VW38,Q9Y371,O15126,Q9H0U4 26 +centrosome 0.2765997429578344 0.2152149557873252 0.8295997310938463 0.9999999999999138 0.862450251009018 30 P0DP25,Q10713,P41208 3 +nuclear_membrane 0.2751454057633535 0.2100683465832283 0.8336143300200392 0.9999999999999426 0.862450251009018 31 Q92973,Q9C0E2,Q14739,P42167 4 +vesicles 0.2987102591171884 0.1732559446472429 0.862450251009018 0.9999999999999978 0.862450251009018 181 Q86Y82,Q15907,O15258,Q8IZA0,P11279,Q15904,P49755,P20020,O75396,Q10713,Q15392,Q06136,Q969V3,Q8NF37,O43808,Q9BTU6,O95470,Q6PHR2,O95674,Q7L5N7,O00264,Q9UEU0,P04439,O00400,P61026,O15269,O14579,Q9UM00,Q9P246,O15400,P61019,Q8NBN3,Q15125,O14653,O15127,Q15363,P00387,Q93050,O15155,O00429,P42345,O95249,Q9P253,Q8IY95,Q5VW38,Q86UL3,Q96L92,Q8NEB9,O43752,Q13277,P05023,O15173,Q9H9H4,Q9Y371,Q9H6H4,Q9H2V7,O96005,Q7Z6M1,Q9H0U4 59 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..25f7a498d0c860637dee0656e819197fcf32383a --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", 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"CDK5", "CDK9", "CDS2", "CEP170", "CETN2", "CHEK1", "CHEK2", "CHMP1A", "CHMP2A", "CHMP4B", "CHMP7", "CHUK", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLINT1", "CLNS1A", "CLPTM1", "CLTA", "CLTB", "CLTC", "CNN2", "COIL", "COMMD2", "COMMD4", "COPA", "COPB2", "COPE", "COPG1", "COPG2", "COPZ1", "CORO1B", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP2", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CYB5R3", "CYP51A1", "DAD1", "DBNL", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DEGS1", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DOCK7", "DPH2", "DRG1", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBNA1BP2", "EBP", "EDC3", "EDC4", "EEA1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC4", "EMC7", 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"LDHB", "LEMD2", "LEMD3", "LIG1", "LMAN1", "LMNA", "LMNB1", "LPCAT1", "LPCAT2", "LSM14B", "LSS", "LTV1", "MAN1A2", "MAP2K1", "MAP4", "MAPK1", "MAPK3", "MAPKAPK2", "MAPRE1", "MBOAT7", "MDH1", "MECP2", "MED24", "MED25", "METAP2", "MFN1", "MFN2", "MIF", "MKI67", "MMGT1", "MPHOSPH10", "MRTO4", "MSH6", "MSN", "MTMR2", "MTOR", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO6", "NAF1", "NANS", "NAPA", "NAPG", "NCAPH", "NCK2", "NCKAP1", "NCL", "NCLN", "NECAP1", "NECAP2", "NEK9", "NEMF", "NHP2", "NIFK", "NMD3", "NOL10", "NOL11", "NOM1", "NONO", "NOP2", "NOP53", "NOP58", "NPM1", "NRBP1", "NSA2", "NSDHL", "NUCKS1", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP214", "NUP35", "NUP98", "NUTF2", "NVL", "NXF1", "OCRL", "OSBP", "OSBPL11", "OSBPL8", "OXSR1", "PABPC4", "PACSIN2", "PACSIN3", "PAIP1", "PAK2", "PARP1", "PBK", "PCNA", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PES1", "PFDN6", "PFN1", "PGK1", "PGRMC1", "PGRMC2", "PHAX", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIK3C3", "PIN4", "PIP4K2C", "PKM", "PKMYT1", "PKN2", "PLK1", "PMPCA", "PMVK", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR3A", "POLR3C", "PPM1G", "PRKCD", "PRKDC", "PRMT9", "PRPF19", "PRPF4B", "PRPF8", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTDSS1", "PTGES3", "PTK7", "PXN", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB3GAP2", "RAB5A", "RAB5B", "RAB7A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGRF", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM3", "RBM34", 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0.1277836657156577 0.1471951297158956 0.2732850813359189 0.0449350347407693 0.0743636419116672 +ATP synthase 5 21 2.0613180895848022 0.0392727035296736 6.381067961165049 20.483009708737864 0.8573640874951715 0.3249378356888472 2.8850015270213047 1.3977105655851854 1.2517106680730556 0.3017789026221172 0.0009326119272623 0.0096266028600564 0.0002069103237917 0.000812960139445 0.0033472823991884 +transmembrane signal receptor 3 7 2.0319582497600805 0.0421578827426452 3.266990291262136 7.169902912621359 1.6693846681257831 0.1085289610325799 1.5770125590990791 1.7927217985188668 1.0928815816574815 0.16461969248918 0.4621355215382663 1.0 0.5903916752900787 0.3859684085300801 0.6609393941288341 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5b0996b12bee8bdfc14e816f06e1220f91786951 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 160, + "title": "Average number of proteins per term", + "value": 13.05 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..815ad32555fa2d048972b9269606d8a752fe3059 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..875a90af5df4aef5985aa31d09fd6cd902ce172c --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,46 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +transporter 0.577908995758886 3.7045706571012342 0.0002117490800404 0.0333158255374802 0.0266333232135097 61 Q99595,O60830,Q9UJZ1,P57740,Q9C0E2,P55060,O15397,Q8N8Q8,Q9H2D1,O14617,Q99805,Q8TEX9,Q92973,Q9HD45,P62072,O00410,O43615,Q8N1F7,P54105,Q567V2,Q99808,P52292,Q15070,Q92544,O43681,Q9Y584,Q7Z3B4,Q8NFH4,Q9Y619,Q9HAV4,Q12769,P48739,O95373,Q9H2V7,Q96P70 35 +calmodulin-related 0.7839151996505924 3.152343386468549 0.0016196567995061 0.228451062722685 0.0863816959736615 13 O43852,Q8IYU8,Q14257,P80303,P0DP25,Q02818,P41208 7 +SNARE protein 0.7053413021796626 3.000483039854404 0.0026955176453216 0.3507030618776778 0.0937432326964469 17 Q86Y82,P56962,O15400,O14653,O43752,Q9P2W9,Q13277,Q9UEU0,O15155,O95249,Q13190 11 +primary active transporter 0.6490049798065844 2.943932233139585 0.0032407095016517 0.4050961693804523 0.0937432326964469 22 Q9BUN8,Q9HAV7,P98194,O60888,Q9NS69,Q8N4H5,P20020,Q6P4A7,O96008,P16615,P05023,O43826,Q15388,Q96B49,O75381 15 +glycosyltransferase 0.5954320715202023 2.5744744119795553 0.0100392512087648 0.8009894602352157 0.1147342995287407 22 P04844,Q96L58,Q9H0U3,Q10472,P46976,O43909,Q9BV10,P15291,Q8NBN7,Q10471,Q9BT22,P46977 12 +mitochondrial carrier protein 0.8388468655094404 2.530544034804183 0.0113885788592018 0.8400074541463314 0.1152534940051186 7 Q9BSK2,Q9HC21,Q9NZJ7,Q9Y6C9,Q70HW3 5 +oxygenase 0.8300957992815583 2.5263533541487218 0.0115253494005118 0.843510280563034 0.1152534940051186 8 Q14534,P30519,Q6UW02,P09601 4 +secondary carrier transporter 0.6729363188727474 2.3669133062531107 0.0179371339207987 0.9447558420472778 0.1445271321993468 12 Q9H936,Q9UJS0,O95202,Q96ES6,O00400,Q8TB61,Q9UBX3,P55011 8 +membrane trafficking regulatory protein 0.5788726672311151 2.308395142511429 0.0209771689232036 0.9663603734580706 0.1461760421870372 19 O43731,P24390,P11279,O43760,O00560,Q8WTV0 6 +acyltransferase 0.5787797814873599 2.3077542997509113 0.0210128060643866 0.9665557286647578 0.1461760421870372 19 P50416,Q86UL3,Q86SQ9,Q9BWD1,P35610,Q8NCC3,P53611,P23786,Q9NUQ2,Q7L5N7,P14324,P49356,Q8NF37 13 +transfer/carrier protein 0.7049223983994558 2.267962910001065 0.0233314674026376 0.977114982062678 0.1493213913768812 10 Q9Y5M8,P17900,P12235,O15127,P12236 5 +protein modifying enzyme 0.5108486176020439 2.2267755163992335 0.0259622804908847 0.9851363991545474 0.1597678799439063 28 Q86YN1,P51812,O60725,Q15418,Q92791,P50897,Q9UMR5,P13674 8 +oxidoreductase 0.450454422292692 2.11837309553774 0.0341434825667381 0.9961450535253348 0.181378952908251 40 O43169,O75306,O15254,O14949,Q86Y39,O96000,Q8N4Q0,P16435,Q15067,O43676,Q96HE7,Q8N0U8 12 +oxidase 0.5940492874048723 2.101285898284665 0.0356158768877277 0.9969799905691804 0.181378952908251 14 O43819,P36551,Q15800,Q9NVS9,Q6ZRP7,O14548,Q8NB78,P14406,O75880,P13073 10 +ATP synthase 0.531260284507127 2.0613180895848022 0.0392727035296736 0.998355549409938 0.1904131080226599 21 P24539,O75964,Q93050,P00846,Q9Y487 5 +transmembrane signal receptor 0.7325974406459472 2.0319582497600805 0.0421578827426452 0.9989836841073324 0.1983900364359774 7 Q99720,O15173,Q96GC9 3 +serine protease 0.5617715543714562 1.9507306655930745 0.0510890934601722 0.9997729768562074 0.2126020089680099 15 O43464,Q4J6C6,Q16740,Q9HB40,P10619,P67812,Q9H3G5,O14773 8 +phospholipase 0.7311677136798758 1.931705619018467 0.0533958508477114 0.9998462041568008 0.2126020089680099 6 Q8IV08,Q9NP80 2 +kinase 0.5125710562371537 1.9230062511578807 0.0544792647980525 0.9998719530692008 0.2126020089680099 21 Q9BRR6,P52789,Q53H12,Q8NEB9,Q9HA64,Q9HBU6,Q8WVC6 7 +voltage-gated ion channel 0.9637800460981216 1.7050038914052876 0.0881936986625246 0.9999996159265612 0.2852012046819606 3 P45880,P21796 2 +glycosidase 0.7249504659361656 1.692049102620845 0.0906366117318577 0.999999749968673 0.2852012046819606 5 Q9BTY2,P06865 2 +metalloprotease 0.4334095524860133 1.5764868849452685 0.1149136389067786 0.9999999967061504 0.3535804274054727 28 Q5JRX3,P42892,Q96E52,Q9UIQ6,Q10713,Q9NZ08,O75844 7 +galactosidase 0.9035549703752472 1.563343885189847 0.1179717312661017 0.9999999981067816 0.3561410755203071 2 P06280 1 +heterotrimeric G-protein 0.6326916175824424 1.5367709185719576 0.1243494173334347 0.999999999407164 0.3617437595154465 7 Q8NHH9 1 +G-protein coupled receptor 0.7802050773244444 1.4003564131705724 0.1614066154117794 0.9999999999994136 0.4304176410980786 4 Q8NBN3 1 +aspartic protease 0.8408911547091706 1.224012265044854 0.2209476007264617 1.0 0.5198767075916746 3 Q8TCT9 1 +nucleotide kinase 0.4566615792032889 1.1917656120878823 0.2333531629892853 1.0 0.5328676671564351 14 Q9UIJ7 1 +amino acid transporter 0.8306286013028167 1.183881366282032 0.236460027300668 1.0 0.5328676671564351 3 O14925 1 +transferase 0.3566377938139297 0.9107378170742776 0.3624335333360218 1.0 0.6721839453528069 29 O43505,P43490,Q99735,O95674,Q06520,Q8NCH0,Q9NRB3,P37268,Q7LGA3 9 +ion channel 0.516737799846956 0.8746575251153796 0.3817602776329645 1.0 0.694109595696299 6 Q9C0H2,Q96S66,P51790 3 +viral or transposable element protein 0.7371549253520906 0.8248081910564515 0.4094804955977764 1.0 0.7004357011294338 3 Q9NUD5 1 +small GTPase 0.4509534634420115 0.8202745819751528 0.4120595931017821 1.0 0.7004357011294338 10 P61225 1 +esterase 0.4890130848641643 0.8135833183731888 0.4158836975456013 1.0 0.7004357011294338 8 Q9NUJ1,Q969T7 2 +chaperone 0.2951383790528822 0.696465322965092 0.4861374666071274 1.0 0.7529527130821272 68 O15260,Q9Y6N1,O14657,Q96KC8,Q9Y2R0,P27824,Q9Y680,P49321,P07237,Q15006,Q96JJ7,Q7KZN9,Q96I36,Q9NWM8,P62942 15 +methyltransferase 0.3730255439315904 0.6177746203967274 0.5367239154744117 1.0 0.7529527130821272 14 P21964 1 +phosphodiesterase 0.5809385506303453 0.5847785415291427 0.5586966347906253 1.0 0.7529527130821272 4 O43924 1 +membrane traffic protein 0.2867645593941682 0.5758530167861342 0.5647145348115954 1.0 0.7529527130821272 67 A6NIH7,Q6NUK4,P43307,Q9NX40,Q96PC5,Q9H6H4,Q9Y2T2 7 +lipase 0.6651553828788308 0.566046154921996 0.5713624052095563 1.0 0.7555205358142894 3 Q9H6V9 1 +reductase 0.3167402650345154 0.5511839385811401 0.5815075891761006 1.0 0.762632903837509 29 P00387,Q14739,Q9UDW1,Q15392,P00374 5 +tubulin 0.4629324546952166 0.4922666050273103 0.6225308847600726 1.0 0.7801598867968922 5 P07437,P04350,P68371,Q9BUF5 4 +lyase 0.3673673162005291 0.4037018258949394 0.6864319967583836 1.0 0.8240807972253766 11 Q9BU89 1 +major histocompatibility complex protein 0.5707740646313952 0.278137745258272 0.7809066218963334 1.0 0.8988853201684414 3 P04439 1 +kinase modulator 0.3742998352553659 0.1672361212498728 0.8671842639666452 1.0 0.9635380710740502 5 P54619,P67870,P10644,P13861 4 +extracellular matrix glycoprotein 0.4812376563528658 0.1065318351879608 0.9151603982909952 1.0 1.0 2 Q32P28 1 +hydrolase 0.2605099769427423 0.0067303444336441 0.9946300026288156 1.0 1.0 19 P07099,Q9BQG2,P15586 3 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6099c4b4a35c00f3224c5573c3535504c6e09262 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "C4 zinc finger nuclear receptor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "amylase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic helix-loop-helix transcription factor", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "hydroxylase", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG8", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC7", "ANKFY1", "ANKHD1", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APOL2", "APP", "APPL1", "APRT", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGDIA", "ARHGEF1", "ARID3B", "ARIH1", "ARL1", "ARL6IP5", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATG7", "ATL2", "ATL3", "ATP11C", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCLAF1", "BDH2", "BET1", "BLM", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRIX1", "BRPF1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CCAR1", "CCAR2", "CCDC88A", "CCDC94", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDS2", "CEBPZ", "CEP170", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP1A", "CHMP2A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNP", "COA3", "COASY", "COG4", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "CORO1B", "CORO1C", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPE", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP2", "CTDP1", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUTA", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAKD", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DEGS1", "DEK", "DENR", "DERL1", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELP1", "EMC2", "EMG1", "ENAH", "ENO1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERCC2", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "FAHD1", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FOXRED2", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GGT7", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM3", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK3", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTRA2", "HUWE1", "IAH1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "ISCU", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFAP3", "KIFC1", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L1RE1", "L2HGDH", "L3HYPDH", "LAMB1", "LAMC1", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LDAH", "LDHA", "LDHB", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM7", "LSS", "LTN1", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MAT2A", "MAT2B", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED24", "MED25", "METAP1", "METAP2", "METTL1", "METTL14", "METTL7B", "MFAP1", "MFSD3", "MFSD5", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MIB1", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MMS19", "MOB4", "MOGS", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL3", "MRPL37", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS14", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTMR2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCBP2", "NCDN", "NCK2", "NCKIPSD", "NCOA5", "ND1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NENF", "NF1", "NFKBIE", "NFS1", "NHP2", "NIP7", "NIPBL", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NPTN", "NR2F2", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PARG", "PARN", "PARP1", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIK3C3", "PIK3R4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTCD1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PUF60", "PUM1", "PURA", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIDA", "RIF1", "RNASEH2A", "RNF14", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRBP1", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SACM1L", "SAE1", "SAMHD1", "SAP18", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN4", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIN3B", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC15A4", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC30A9", "SLC33A1", "SLC35B2", "SLC37A4", "SLC4A1AP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNAP29", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STK4", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARS", "TARS2", "TBC1D10A", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TDRKH", "TECR", "TES", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIA1", 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0000000000000000000000000000000000000000..82d45a5b086527b83a5c884e6a2e4f49b5b5cf37 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,14 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +SLC superfamily of solute carriers 24 44 3.8820792178690735 0.000103567125071 18.888349514563107 44.33009708737864 2.1618907004737498 0.1690913715307362 9.633686860107934 5.825351940723624 1.7350998035598977 0.2760301582542676 0.001473814772073 0.2177059049323894 0.001815615318323 0.0047362689607466 0.0002009003847054 +SLC25 family of mitochondrial transporters 12 20 3.470728348998588 0.0005190488078605 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 6.993845449875131e-08 0.0135379522122687 2.5288360625722612e-05 1.7091972697716228e-07 8.896897464501222e-09 +Transporter 88 192 3.2685734862510016 0.0010809110441265 57.59466019417476 188.27912621359224 1.4971900036635353 0.4160578104205245 21.77919356765414 18.57070590158326 1.926868489654782 0.421013047757716 7.781438025053836e-09 0.0082689013210767 1.4813588624641798e-05 2.3214634722344343e-06 1.759978407084557e-13 +SNARE protein 11 16 3.032607796253006 0.0024245048610616 4.555825242718447 10.6626213592233 0.9494792984446184 0.3117420251981136 2.5225757464631977 2.583604188764985 1.1633177546874711 0.3031193116521645 0.0004261431239591 0.1221118561195742 0.2297987482657219 0.1383652025719425 2.7061211228180336e-07 +Mitochondrial nucleotide transporter subfamily 8 9 2.874993988684988 0.00404035190279 4.216019417475728 9.065533980582524 1.5870110662923598 0.1668197633609344 2.720728714423222 1.1029864386277723 1.1616247375257451 0.2431804664231326 5.224055641143196e-07 0.0022827689145391 0.0003602808960722 1.972516813028553e-05 5.472833483072756e-09 +Calcium-binding protein 7 19 2.686200864719985 0.0072269628090535 6.135922330097087 18.021844660194176 1.3650952896045327 0.2072953623045914 2.3371152398743247 2.2037057261181348 1.237653756718734 0.2545563939054063 0.0002895156623025 0.001369405333307 0.0009611330378982 0.0048857385669874 0.0003118568141161 +Calmodulin 7 16 2.409616847212988 0.0159692815119087 5.330097087378641 14.50728155339806 1.3338669185027796 0.2094989649985028 2.1356354617596836 1.8597539737980884 1.176586593960994 0.2465515447823433 0.0001563684143996 0.0102371045657047 0.0034893000144238 0.0070923684446229 0.0001106790733064 +Intracellular calcium-sensing protein 7 16 2.409616847212988 0.0159692815119087 5.330097087378641 14.50728155339806 1.3338669185027796 0.2094989649985028 2.1356354617596836 1.8597539737980884 1.176586593960994 0.2465515447823433 0.0001563684143996 0.0102371045657047 0.0034893000144238 0.0070923684446229 0.0001106790733064 +Glycosyltransferase 9 17 2.4053490200599934 0.0161570266439681 5.713592233009709 16.264563106796118 0.58827010515732 0.444796659838118 2.8207810163966904 2.842193627279741 1.1276277753027448 0.3350616775048655 0.0313634261071185 1.0 1.0 0.0180040169030602 0.0848455502145762 +Acyltransferase 8 12 2.36700934368422 0.0179324800760063 3.1067961165048543 9.41504854368932 0.3809422525127639 0.5105103319247358 1.8677779818542355 1.784525377484509 0.9351567129762406 0.3147395520597634 0.1110967103239431 0.1389130578490434 0.2590666885683055 0.1724444479617574 0.0159032502878613 +Receptor 7 27 2.286744243950473 0.022210755603774 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 0.0475525321092517 0.4014813083941581 0.271213554068588 0.0436986166677031 0.1439737634596783 +G-protein 8 30 2.1329714970133216 0.0329270644516384 9.16504854368932 31.45631067961165 0.0011471809144722 0.7666781564984295 6.065735514159894 3.3632124582607785 0.5787245100431045 0.2676858497293656 0.1988521112021424 1.0 1.0 0.3195580599455 0.0177508820512533 +F-type and V-type ATPases 4 16 2.105356336131388 0.0352603016017434 4.995145631067961 15.616504854368932 0.6819760311565471 0.3553057475304781 2.5561606009064737 1.187932616128487 1.149561543758102 0.2999604229905949 0.001449857738388 0.0053672672920639 0.0013262573806951 0.0020705519968491 0.0043329575683166 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..856cf4ee4dfebb0e01e6b8b831295ca7e3547204 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 1972, + "title": "Average number of proteins per term", + "value": 3.120182555780933 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..27556fab401bacbef6f8cedc2f9a935d8d5a7b6a --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..78db13356514801f0c215e8104c0ab395c24d767 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,67 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +SLC superfamily of solute carriers 0.6398885189400295 3.8820792178690744 0.000103567125071 0.184737349701079 0.0834860045108285 44 Q9HC21,P05141,Q9NZJ7,P12236,O43826,Q9H2D1,Q00325,Q9Y6C9,O43808,Q9BSK2,Q9H0U3,P12235,Q6NUK1,O00400,Q9UBX3,Q99808,Q70HW3,Q9Y619,Q9HC07,Q9UJS0,O95202,Q7L0J3,Q9H2V7,Q8TB61 24 +SLC25 family of mitochondrial transporters 0.7498883504613915 3.4707283489985876 0.0005190488078605 0.6407834902154732 0.0834860045108285 20 Q9BSK2,Q9HC21,P05141,Q9NZJ7,P12235,P12236,Q6NUK1,Q9Y619,Q9H2D1,Q9Y6C9,Q9UBX3,Q70HW3 12 +Transporter 0.5251809255073161 3.2685734862510016 0.0010809110441265 0.8814842506537753 0.0834860045108285 192 Q86Y82,P98194,P49755,Q9BQE5,Q9H2D1,P00846,Q00325,Q9BSK2,P24390,P24539,P51572,Q9P2W9,O00400,Q9Y3B3,Q9UBX3,Q70HW3,Q15070,Q9Y584,Q15363,Q9Y619,O95721,O43760,Q9Y487,Q9Y3A6,Q9HC07,P56134,Q12907,Q9UJS0,Q12769,O43752,Q9H6H4,Q9H2V7,P55011,Q6NUK4,P20020,Q9NZJ7,P12236,Q9Y6C9,P28288,Q8TEX9,Q9HD45,P17900,P12235,Q96ES6,Q15388,P53680,O00560,O14579,Q92544,Q9H936,O43731,P54709,Q93050,Q8TB61,Q9HC21,P11279,Q9C0E2,Q6NUK1,Q03518,Q99808,Q13190,Q00765,Q8NFH4,P16615,O15155,O95249,P56385,Q13277,Q7L0J3,P05141,O43826,O43808,Q9H0U3,Q99805,Q92973,Q9UEU0,Q8N1F7,P54105,P52292,O15400,P56962,O14653,Q7Z3B4,Q9P253,O96008,O95202,O75027,P05023 88 +SNARE protein 0.7240882858433167 3.032607796253006 0.0024245048610616 0.9916619749894418 0.0834860045108285 16 Q86Y82,P56962,O15400,O14653,O43752,Q9P2W9,Q13277,Q9UEU0,O15155,O95249,Q13190 11 +Mitochondrial nucleotide transporter subfamily 0.866050808314078 2.8749939886849876 0.00404035190279 0.9996590290724612 0.0834860045108285 9 Q9BSK2,Q9HC21,P05141,P12235,P12236,Q6NUK1,Q9H2D1,Q70HW3 8 +Calcium-binding protein 0.6348754697594374 2.686200864719985 0.0072269628090535 0.9999993860288596 0.0834860045108285 19 O43852,P43307,Q14257,P80303,P0DP25,Q02818,P41208 7 +Calmodulin 0.6227260322675444 2.409616847212988 0.0159692815119087 0.9999999999999836 0.0929338522953628 16 O43852,Q8IYU8,P80303,Q14257,P0DP25,Q02818,P41208 7 +Intracellular calcium-sensing protein 0.6227260322675444 2.409616847212988 0.0159692815119087 0.9999999999999836 0.0929338522953628 16 O43852,Q8IYU8,P80303,Q14257,P0DP25,Q02818,P41208 7 +Glycosyltransferase 0.6110394259128556 2.4053490200599934 0.0161570266439681 0.9999999999999888 0.0929338522953628 17 P04844,Q8N128,Q10472,P46976,P15291,Q9BV10,Q10471,Q9BT22,P46977 9 +Acyltransferase 0.6729530908270065 2.36700934368422 0.0179324800760063 0.9999999999999996 0.0958342837666246 12 Q86SQ9,P35610,P53611,Q7L5N7,P14324,P49356,Q9UJ14,Q8NF37 8 +Receptor 0.521633961357263 2.286744243950473 0.022210755603774 1.0 0.1050873084106175 27 Q9BUN8,Q08AM6,A6NIH7,Q14108,P57105,Q567V2,Q8WTV0 7 +G-protein 0.4926720330156571 2.1329714970133216 0.0329270644516384 1.0 0.1259213278213855 30 O60313,Q9NTK5,P61225,Q8NHH9,O15397,O95373,Q15382,P63218 8 +F-type and V-type ATPases 0.5759137755632799 2.1053563361313876 0.0352603016017434 1.0 0.1314429390522458 16 Q93050,P24539,Q9Y487,P00846 4 +P-type ATPases 0.7063282794990046 1.8130864330952767 0.0698184913294892 1.0 0.1863086128575816 6 P98194,P20020,P54709,P16615,P05023 5 +Signaling 0.5061400771659293 1.791878201505162 0.0731524784809427 1.0 0.1920861352389069 19 P43490,Q96PC5,Q07820,O00264,Q96GC9,O15173 6 +Miscellaneous SLC25 mitochondrial transporters 0.9493087557603688 1.7573331617113297 0.0788610385517403 1.0 0.2014429637616993 2 Q9NZJ7 1 +Membrane trafficking regulatory protein 0.4878015736494568 1.7365431576021504 0.0824678402742786 1.0 0.2061173396969297 21 O43731,O00560,O43760,P24390 4 +Oxidase 0.4859890066815452 1.6818049935935817 0.0926066601030375 1.0 0.2195505321201976 20 O43169,O15260,O15254,Q15800,Q15067,Q6ZRP7,P14406,O75880 8 +Esterase 0.5622676686339718 1.5854371892362142 0.1128670372247391 1.0 0.2443726418481545 11 P50897,Q9UMR5 2 +Lipid kinase 0.6502405589416693 1.5402891331260598 0.1234898914463391 1.0 0.2588055349698689 6 Q8NEB9 1 +Heterotrimeric G-protein 0.6326916175824424 1.5367709185719576 0.1243494173334347 1.0 0.2597638251923022 7 Q8NHH9 1 +F-type ATPase 0.6260950817609816 1.5309056691610805 0.1257927079209415 1.0 0.2617468846548689 8 P56134,P24539,P06576,P00846,P56385 5 +Aspartic protease 0.810328012647942 1.5260781584316538 0.1269904008384546 1.0 0.2632080887609537 4 Q8TCT9 1 +Serine protease 0.4301669672443324 1.4116822022824946 0.158043556099358 1.0 0.3031730473034378 24 Q9HB40,Q92945,Q96AE4,P61978,P10619,P67812,Q9H3G5,O14773 8 +Methyltransferase 0.4775461936778257 1.3807954244873355 0.1673418707487917 1.0 0.3115739102320569 15 Q9UBP6,P21964 2 +RSK subfamily 0.8357472021066377 1.275326216878231 0.2021938020269671 1.0 0.3504450613732943 2 P51812 1 +RSK family 0.8357472021066377 1.275326216878231 0.2021938020269671 1.0 0.3504450613732943 2 P51812 1 +Small GTPase 0.4226074819512594 1.2669036300048149 0.2051897506103097 1.0 0.3533923041078872 22 O60313,P61225,O15397,O95373,Q15382 5 +Mitochondrial amino acid transporter subfamily 0.6312112022970108 1.2578845708997952 0.2084335044235228 1.0 0.3573509188508898 5 Q9Y619,Q9UJS0 2 +V-type ATPase 0.5733564960118809 1.2569914727213352 0.2087567233855096 1.0 0.3573509188508898 8 Q9Y487 1 +Reductase 0.444820065971187 1.1980283591028649 0.2309059768437116 1.0 0.3794951866254515 16 Q14739,Q9UDW1,Q15392 3 +PI3/PI4 kinase family 0.7246212733374615 1.1675455354535131 0.2429901304829891 1.0 0.3927676535347988 4 Q8NEB9 1 +Extracellular structure 0.4937145792541288 1.0731512481119807 0.2832032603478767 1.0 0.4299282751393478 10 Q92791,Q9Y2T2 2 +Phosphatase inhibitor 0.5537708605084439 1.0596535509237333 0.2893022415569339 1.0 0.4359436304027441 6 Q99733,Q01105 2 +Ca2+-ATPases 0.7872900889035173 1.01551073310733 0.3098624328848596 1.0 0.4580575094819663 3 P16615,P98194 2 +Na+/K+-ATPases 0.7653061224489806 0.9805691842292852 0.3268052368765031 1.0 0.4714410586104346 2 P05023 1 +Metalloprotease 0.3406511227134607 0.9773799888316006 0.3283810661675996 1.0 0.4733680281304872 39 Q5JRX3,P42892,Q96E52,Q9UIQ6,Q10713,Q9NZ08,O75844 7 +Ion channel 0.5176597431210607 0.9639962230355876 0.3350478194784174 1.0 0.4787358260822871 8 Q9C0H2,P51798,Q96S66,P51790,Q8NE86 5 +Galactosidase 0.753456221198137 0.9320349907068044 0.3513184426021924 1.0 0.4935085066398347 2 P16278 1 +Oxygenase 0.5212096649296314 0.8968994645943559 0.3697725658299815 1.0 0.5063023801664502 6 Q14534 1 +AGC group 0.4937360578534181 0.820825277880337 0.4117457979751333 1.0 0.5413084757379752 7 P51812,Q05655 2 +Chloride channel family 0.7215273206056627 0.8036763394708082 0.4215839221606341 1.0 0.548800516891229 2 P51790 1 +Protease inhibitor 0.4462078069690842 0.7923318361287403 0.4281672131936105 1.0 0.5540326406940944 10 Q9UJZ1,P04080,P05067,P27105 4 +Transaminase 0.5280743306422462 0.778383591737862 0.4363429089557424 1.0 0.5616633266714909 5 O15269,O15270 2 +Ubiquitin-protein ligase 0.3901351980911937 0.7671272590178423 0.4430058562647916 1.0 0.5665418602815623 15 O94822,Q9HB71,Q9UBS8 3 +Growth factor 0.5235771538673737 0.7579396400377251 0.4484871182247403 1.0 0.5709597140988947 5 Q96PC5 1 +Protease 0.2943376732895318 0.7117324409257961 0.4766304749181835 1.0 0.5909124187205662 104 Q7Z2K6,Q99538,Q96E52,Q9UIQ6,Q10713,O14773,Q92820,Q13510,P67812,O75844,Q99797,Q8TC07,Q96K76,Q9HB40,P42892,P10619,Q9NZ08,Q5JRX3,Q8TCT8,Q92643,Q92945,Q8NHP8,Q96FW1,P55786,Q9H3G5,Q8TCT9 26 +PDHK family 0.6942067149440434 0.697455452084912 0.4855178089905698 1.0 0.5980269327479099 2 Q15118 1 +Lyase 0.3601025932654267 0.685269085391903 0.4931741360040176 1.0 0.6044371635798153 19 O96005,Q96KA5 2 +Phosphatase modulator 0.458395056103853 0.654852309959657 0.5125628475259498 1.0 0.6202929432359013 8 Q99733,Q01105 2 +Non-protein kinase 0.3432927554528195 0.5584623280409685 0.576528722079106 1.0 0.6617663794761333 19 Q9UIJ7 1 +Damaged DNA-binding protein 0.5622919444901805 0.5150971770572385 0.6064851152690944 1.0 0.681863538945641 4 Q9NQE9 1 +Tubulin 0.4629324546952166 0.4922666050273103 0.6225308847600726 1.0 0.6912254792968403 5 P07437,P04350,P68371,Q9BUF5 4 +Other group 0.3467664770637223 0.4689343872793076 0.6391165358051465 1.0 0.6994105486169527 15 Q99640,O60566,O14965,Q96KB5 4 +Protein arginine methyltransferase 0.4825428194993477 0.250212992513792 0.8024226381922961 1.0 0.8160791348711748 4 O60678,Q99873,Q86X55 3 +SLC30 zinc transporter family 0.5503620803159992 0.2376781459614154 0.8121307350005764 1.0 0.8255267058871839 2 Q8NEW0 1 +CDK family 0.3721160184574832 0.2171229994328908 0.8281124905229469 1.0 0.8400400366827424 6 Q00534,P06493,P11802,P24941,P50750 5 +Nucleotide phosphatase 0.3551113969264623 0.1725973152087626 0.8629679623797817 1.0 0.8740487014961117 7 O43681,Q8IWA4,Q9H857 3 +CDK4 subfamily 0.5049374588545116 0.1438837630987517 0.8855922574349606 1.0 0.8955835546983294 2 P11802 1 +Kinase activator 0.36177924217463 0.1307830859442466 0.8959469035232108 1.0 0.9055906169901444 5 O95067,Q16543,P14635,Q9Y3A3 4 +Atypical group 0.4317002065263477 0.1203560152334562 0.9042011328107956 1.0 0.9134654886797589 4 Q15118,P42345 2 +CDK1 subfamily 0.4828834759710355 0.1088733858387903 0.9133029161619504 1.0 0.9221880955818568 2 P24941 1 +Oxidoreductase 0.2571094732659752 0.086590030498145 0.9309973906449944 1.0 0.9395736204462276 114 O43169,Q16850,P14406,Q9UDW1,Q15392,O75880,Q9NZ01,Q9P0J0,O15254,Q8NCN5,P31350,O75438,Q96HE7,O15260,Q14534,P03886,Q15067,P00374,O75306,Q96CU9,Q15800,Q8N4Q0,O95168,Q6ZRP7,Q14739,Q9HBH5,Q8N0U8,Q13423 28 +Protein methyltransferase 0.3200395517468765 0.0468518964123679 0.962631267060291 1.0 0.9685249278790274 6 Q86X55,O14744,Q99873,O96028,O60678 5 +Cadherin 0.3578011849901277 0.0175288092499569 0.9860147499165524 1.0 0.9915456842608064 2 Q14126 1 +PIKK family 0.3179723502304176 0.0117466039883336 0.9906277815703476 1.0 0.995676852832174 2 P42345 1 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3d4b9354c91f2b42cab0be809015f77f6abf9d54 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1,4-alpha-glucan-branching enzyme", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S14, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L16, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L23, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 2/3 complex subunit 5", "Actin-related protein 3", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amylase", "Amyloid-beta A4 protein", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Annexin", "Antibacterial response protein", "Antigen peptide transporter 1", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arfaptin-2", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2", "Ataxin-2-like protein", "Atlastin-2", "Atlastin-3", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical SLC22B subfamily", "Atypical group", "Aurora kinase a", "B-cell receptor-associated protein 29", "B-cell receptor-associated protein 31", "BET1 homolog", "BTB/POZ domain-containing protein KCTD12", "BUB family", "BUB3-interacting and GLEBS motif-containing protein ZNF207", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-1,4-galactosyltransferase 1", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Beta-mannosidase", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional coenzyme A synthase", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Bromodomain", "Bromodomain-containing protein 2", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 3", "CCR4-NOT transcription complex subunit 4", "CCR4-NOT transcription complex subunit 7", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CHK1 subfamily", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "COUP-TF-like receptors", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type ii subunit delta", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 12", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Chaperone", "Chaperonin", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Coup transcription factor 2", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-associated NEDD8-dissociated protein 1", "Cyclase", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystathionine gamma-lyase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DDB1- and CUL4-associated factor 13", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrodolichyl diphosphate synthase complex subunit DHDDS", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidylate deaminase", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Desmocollin-2", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Diphthine methyl ester synthase", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase MIB1", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongin-B", "Endodeoxyribonuclease", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Epidermal growth factor receptor substrate 15", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethanolamine kinase 1", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FAD-dependent oxidoreductase domain-containing protein 2", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Folate transporter 1", "Forkhead box protein C1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit beta", "Girdin", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate exchanger SLC37A4", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione hydrolase 7", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi SNAP receptor complex member 2", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 3", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inhibitor of nuclear factor kappa-b kinase subunit beta", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intersectin-2", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-associated protein 3", "Kinesin-like protein KIF11", "Kinesin-like protein KIF13B", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIFC1", "Kinetochore protein NDC80 homolog", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Legumain", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophosphatidylcholine acyltransferase 2", "Lysophospholipid acyltransferase 5", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "M-phase phosphoprotein 8", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAPK family", "MAPKAPK family", "MAPKAPK subfamily", "MCU family", "MFS-type transporter SLC18B1", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MST subfamily", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Map kinase-activated protein kinase 2", "Mediator of RNA polymerase II transcription subunit 25", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metalloendopeptidase OMA1, mitochondrial", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine aminopeptidase 1", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Methyltransferase-like protein 7B", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 3", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "N-acetyl-D-glucosamine kinase", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "N6-adenosine-methyltransferase non-catalytic subunit", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurofibromin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear cap-binding protein subunit 2", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "OCIA domain-containing protein 1", "Obg-like ATPase 1", "Origin recognition complex subunit 3", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P53-like transcription factor", "PAKA subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 3", "PDZ and LIM domain protein 5", "PEK family", "PH-interacting protein", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "Paired amphipathic helix protein Sin3a", "Paired amphipathic helix protein Sin3b", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Paxillin", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase catalytic subunit type 3", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphodiesterase", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phospholipid-transporting ATPase IG", "Phospholipid-transporting ATPases", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Phosphoserine phosphatase", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable leucine--tRNA ligase, mitochondrial", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl 3-hydroxylase 3", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein Hook homolog 3", "Protein LSM14 homolog B", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein VAC14 homolog", "Protein Wiz", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c delta type", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyridoxine-5'-phosphate oxidase", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA polymerase II subunit A C-terminal domain phosphatase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-2", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Remodeling and spacing factor 1", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal RNA-processing protein 7 homolog A", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 2 homolog", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC15 family of peptide transporters", "SLC16 family of monocarboxylate transporters", "SLC18 family of vesicular amine transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC37 family of phosphosugar/phosphate exchangers", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Segment polarity protein dishevelled homolog DVL-2", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Septin-11", "Septin-2", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 12", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk1", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase ulk3", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 15 member 4", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptic vesicle glycoprotein 2A", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Syntaxin-10", "Syntaxin-12", "Syntaxin-17", "Syntaxin-18", "Syntaxin-3", "Syntaxin-5", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "T-complex protein 11-like protein 1", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 10A", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Testin", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Torsin-1B", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation initiation factor", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-3", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2B chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase yes", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm4", "U6 snRNA-associated Sm-like protein LSm7", "UDP-glucose:glycoprotein glucosyltransferase 1", "UDP-glucuronic acid decarboxylase 1", "ULK family", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4B", "Vacuole membrane protein 1", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle transport through interaction with t-SNAREs homolog 1B", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "WNK family", "Winged helix/forkhead transcription factor", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 281", "Zinc finger protein 593", "Zinc finger protein 622", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 7", "Zinc transporter 9", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG12", "ALG8", "ALYREF", "ANAPC1", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APOL2", "APP", "ARCN1", "ARFIP1", "ARFIP2", "ARHGDIA", "ARID3B", "ARIH1", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B4GALT1", "BAG6", "BAIAP2", "BCAP29", "BCAP31", "BCAS2", "BCLAF1", "BET1", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRD2", "BRIX1", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC88A", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC37", "CDC40", "CDC42", "CDC45", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CEBPZ", "CEP170", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "CORO1B", "CORO1C", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP2", "CTDP1", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCPS", "DCTD", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHX15", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELMO2", "ELMOD2", "ELOB", "ELP1", "EMC2", "EMG1", "ENO1", "EPHA7", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FNTB", "FOXC1", "FOXRED1", "FOXRED2", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GCAT", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GGT7", "GLB1", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GOSR2", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2F1", "GTF2F2", "GTF3C3", "GTF3C5", "GTPBP1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HEATR1", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK3", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFAP3", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LRRC47", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM7", "LTN1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCH5", "MAT2A", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED25", "METAP1", "METTL1", "METTL14", "METTL7B", "MFAP1", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MIB1", "MICU1", "MICU2", "MIPEP", "MMS19", "MOB4", "MORF4L1", "MORF4L2", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL14", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS14", "MRPS16", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCBP2", "NCL", "NCOA5", "ND1", "NDC80", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS7", "NEDD4L", "NEK9", "NF1", "NFS1", "NHP2", "NIPBL", "NKRF", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NPTN", "NR2F2", "NRBP1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCRL", "OLA1", "OMA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H3", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAIP1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3C3", "PIK3R4", "PINX1", "PIP4K2C", "PIR", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL1", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA2", "PRKAG1", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PSPH", "PTCD1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PUM1", "PURA", "PXMP2", "PXN", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGGTB", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RNASEH2A", "RNF14", "RNH1", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RTCA", "S100A10", "S100A11", "SAE1", "SAP18", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT2", "SKP1", "SLC12A2", "SLC15A4", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMN1*", "SNAP23", "SNAP29", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TAP1", "TARS", "TARS2", "TBC1D10A", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCP1", "TCP11L1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM22", "TJP1", "TJP2", "TK1", "TKT", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM165", "TMEM97", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRMT6", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSTA3", "TTYH3", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UCHL5", "UCK2", "UGGT1", "ULK3", "UNC119B", "UPF1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP19", "USP39", "USP47", "USP5", "USP7", "UTP11", "UTP14A", "UTP3", "UTP6", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VMP1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4B", "VRK1", "VRK2", "VTI1B", "WARS", "WDHD1", "WDR1", "WDR74", "WDR82", "WIZ", "WNK1", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS4", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF207", "ZNF281", "ZNF593", "ZNF598", "ZNF622", "ZW10", "ZYX"], "leading_proteins": ["ABCB7", "ABCD3", "ACOX1", "ACOX3", "AK3", "ALG1", "ALG12", "AP2S1", "AP3M1", "APOL2", "APP", "ASAH1", "ASNA1", "ATL2", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5F1", "ATP5I", "ATP5J2", "ATP6", "ATP6V0A1", "ATP6V0A2", "AURKA", "B4GALT1", "BCAP31", "BET1", "BUB1B", "CACYBP", "CALM3", "CALU", "CARM1", "CCNB1", "CCNB2", "CDC37", "CDK1", "CDK2", "CDK4", "CDK6", "CDK9", "CETN2", "CLCC1", "CLCN3", "CLCN7", "CLNS1A", "CLPTM1", "CLPTM1L", "COMT", "COPE", "COX7A2", "CPVL", "CSTB", "CTSA", "CYB5B", "CYP51A1", "DERL1", "DHCR24", "DHDDS", "DHFR", "DSG2", "ECE1", "ERAP1", "ERMP1", "ERO1A", "FAM177A1", "FDPS", "FNTB", "FOXRED1", "FUBP1", "GALNT1", "GALNT2", "GGH", "GGT7", "GLB1", "GM2A", "GNG5", "GOSR1", "GOSR2", "GYG1", "HINT3", "HM13", "HNRNPK", "IPO4", "IPO7", "IPO8", "KDELR1", "KDELR3", "KHSRP", "KPNA2", "LAMP1", "LBR", "LETM1", "LGMN", "LMAN2", "LNPEP", "LPCAT1", "LPCAT2", "LTN1", "MAGT1", "MCL1", "MCU", "METTL1", "MFN1", "MFSD3", "MIA2", "MICU2", "MIPEP", "MOB4", "MPV17L2", "MSMO1", "MTCH1", "MTCH2", "MTOR", "NAMPT", "NAP1L4", "ND1", "NDUFA13", "NDUFB1", "NDUFB4", "NDUFS2", "NNT", "NPEPPS", "NSD2", "NT5DC2", "NUCB1", "NUCB2", "NUP160", "NUP37", "NUP54", "NUP93", "OLA1", "OMA1", "OPA1", "OTUB1", "OXA1L", "P3H4", "PBK", "PDK1", "PDPR", "PGRMC1", "PGRMC2", "PIGK", "PIK3C3", "PITRM1", "PKMYT1", "PLBD2", "PMPCA", "PPT1", "PPT2", "PRKCD", "PRMT1", "PRMT3", "PRMT5", "QSOX2", "RABGGTB", "RAP2B", "RCN2", "RDH14", "REEP3", "REEP4", "REEP5", "RHEB", "RNF14", "RPN2", "RPS6KA3", "RRM2", "SCARB1", "SCARB2", "SCO1", "SCPEP1", "SDCBP", "SEC11A", "SET", "SLC12A2", "SLC25A10", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC29A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC37A4", "SNAP29", "SOAT1", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SSR1", "STOM", "STOML2", "STT3A", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "SURF4", "SV2A", "SYNGR2", "SYNJ2BP", "TAP1", "TBC1D15", "TECR", "TIMM22", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMEM165", "TNPO1", "TOMM20", "TOMM40", "TPP1", "TTYH3", "TUBB", "TUBB4A", "TUBB4B", "TUBB6", "UNC119B", "UQCR10", "USP47", "VAC14", "VKORC1L1", "VMP1", "VPS18", "VTI1B", "XPO4", "ZADH2", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c2c9a89814544d67cab453c74790749979179bf3 --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..20c21bd273deb77374ce7c53ac345c64c2735c74 --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:24b29aba4800754b368a9d6e1dd9662343e8c0e3b0e821797f3fd59917c4c08e +size 188093 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a0739b7a1518393d576dba30d8ec5942decce175 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tclin", "1": "Tdark"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..87c18b60bf3836a1dec8de7bc605accea2052bbc --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bb57f29c5349eef000767a7f0013e210d46b7f5cea2415e70e6745ea0e8893dd +size 131520 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..100f7c45483e1ac6934f7bef47736b42757b9505 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a85b7e4ca4fc0dd18ee9181ab0ad7e57ee0f46304f347942e37cdd8c6d9ace85 +size 134762 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..6a7327bbac7edc59055184d8fc951381772042b7 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e228786c5013d2396624198cd2538cf646ad2c84931892d346c63184f158bc72 +size 76407 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ce6b1db2ae575f31de7f77e31aba22f071e388bd --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tclin 22 82 2.166594190083027 0.0302658107983289 19.366504854368937 86.39077669902913 0.9399778874953114 0.4805096456956057 6.659845213621253 7.009024167820235 0.9745051203556824 0.3806460486794667 0.0016476442012957 1.0 0.352110710507972 0.017599669321684 0.0009867571279467 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4c888e41bd5da8c29a6521a7a1dabad2ef139d76 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 759.75 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b609dd513ddadba3b19489ca91bf16547b38070e --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b99e73627f2f79c9d70ce3eb6443061089689b52 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tclin 0.3827589421635257 2.166594190083027 0.0302658107983289 0.1156771845499529 0.0605316215966578 82 Q86Y39,Q99720,O96000,P14324,P10253,P62942,Q9P0J0,P06280,P49721,O75438,Q99808,O43924,P03886,P0DP25,O43676,P21964,P00374,O75306,P38435,O95168,Q7L0J3,Q05655 22 +Tdark 0.4067220540433896 1.4825679695586416 0.1381892324757672 0.4483702710178363 0.1842523099676896 307 Q86YN1,Q8N4H5,Q9H2W6,Q7Z2K6,Q92575,Q9NX00,O60830,Q9Y6I9,P14406,P84157,Q3SXM5,Q96B49,Q9NPA0,Q9H1E5,Q9Y426,Q9NPR9,Q6ZU35,O60783,O43615,Q8NC54,Q6UW02,Q9Y3B3,Q96DB5,Q92564,Q5T2E6,Q8NBN3,O75964,Q9H4I3,Q7Z3D4,Q9NRY5,Q5VW38,Q96EX1,Q69YU5,O94919,O95070,Q9NUQ9,Q15629,Q9BU23,Q8N128,Q70UQ0,Q8NBN7,Q9HD45,Q96P47,Q9H330,Q9Y6J9,Q96ES6,Q9HD20,Q8WVC6,O43731,Q9NUD5,Q9BWH2,Q9Y5M8,Q969T7,Q8N4V1,Q96CP7,L0R6Q1,O95302,Q96SK2,Q6ZXV5,Q9NQE9,O75071,Q8IZ73,Q8NFH4,O15155,Q6NUQ4,Q7Z7F7,P82933,Q9BVG4,Q6UW68,Q8TDW0,Q9BW72,Q9H1Z9,Q7Z4Q2,O75935,Q96LJ7,Q9BSJ2,Q8WZA9,Q99805,P17152,Q8TBQ9,Q15006,Q9UH62,Q9H857,Q9NX62,Q96DE5,Q9H7E9,Q9NPL8,Q96CN7,Q5SNT2,Q9NW68,Q86U38 91 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..80a27f94063610b6f8e5ffc51ad50f85c57fa39d --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG8", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANKFY1", "ANKHD1", "ANKLE2", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATG13", "ATG16L1", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BDH2", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRI3BP", "BRIX1", "BROX", "BRPF1", "BSDC1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf76", "C11orf58", "C12orf43", "C12orf73", "C14orf2", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C20orf24", "C2CD2", "C2orf49", "C5orf15", "C5orf24", "C8orf33", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCDC88A", "CCDC93", "CCDC94", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPK", "CENPU", "CENPV", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG4", "COIL", "COLEC12", "COLGALT1", "COMMD2", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPE", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP2", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP2", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERCC2", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM162A", "FAM177A1", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FOXRED2", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD2A", "HIKESHI", "HINT3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1211", "KIAA2013", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFAP3", "KIFBP", "KIFC1", "KLC1", "KLC2", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L2HGDH", "L3HYPDH", "LAMB1", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD1L1", "MAGED2", "MAGT1", "MAK16", "MAN1A2", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAPK1", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCH5", "MARCKS", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBIP", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED24", "MED25", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL14", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MIB1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL3", "MRPL37", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS14", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MXRA7", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NACC1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F2", "NRBP1", "NRDC", "NRM", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OSTM1", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11A", "PEX14", "PEX16", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PWP2", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG2", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC15A4", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC4A1AP", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG8", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D10A", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TCP11L1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLCD1", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM33", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMLHE", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN6", "TSR1", "TSR2", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF2", "U2SURP", "UAP1", 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https://git-lfs.github.com/spec/v1 +oid sha256:985dfc21e4b312063cff41125791fbad5012b5598a8d7ca98511adb3ca2f4394 +size 88965 diff --git a/protein_atlas_biological_process/df_merge.tsv b/protein_atlas_biological_process/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..842a4be9c29c9d24f4deb8d189590f5bacb54554 --- /dev/null +++ b/protein_atlas_biological_process/df_merge.tsv @@ -0,0 +1,17 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transport 207 491 4.202399493653804 2.641005184012002e-05 127.39320388349516 491.7621359223301 1.4832290368286314 0.5289485259644714 40.31460927260851 50.077723312236 2.248556521823017 0.4543981544818752 1.6280181358866738e-17 1.6105662650021224e-11 3.0905472624379594e-14 5.570057592812587e-14 5.440062990005377e-20 +Ion transport 32 51 3.4412691067463896 0.0005789923825905 19.82766990291262 54.68446601941748 1.177785596906995 0.303722365376275 8.99659651977233 7.41832233515522 1.8666057057567336 0.3607289685223158 0.0143096490569055 0.0021892244153217 0.0005060084606059 0.0070264390813363 0.0123189934194897 +Translocation 20 50 3.3644641209313435 0.0007669245509218 12.434466019417476 47.86165048543689 1.1297087783550883 0.3515144245437065 6.687771513864753 3.601211391947168 1.550426642680832 0.3811939235350816 3.440600220488492e-06 2.6116330706367664e-05 6.493581403491033e-06 1.0679246842113709e-05 2.0959915925833104e-06 +Electron transport 16 44 3.17088895919233 0.0015197322377549 14.983009708737864 45.592233009708735 1.1180311721330871 0.3315827540150002 5.69510117113123 4.184313965655804 1.5984402393879058 0.3574888993156041 1.5667333948840285e-05 0.0011750725005975 0.0023748989920053 0.0023912319011254 3.6955559870808975e-06 +Respiratory chain 12 30 3.073493621538011 0.0021156821045764 10.895631067961164 31.91990291262136 1.1075564231308468 0.3095707256998049 4.44287149555612 3.6670789399383112 1.4970961025113558 0.3356221172021658 1.508719553343968e-05 0.0345877004093447 0.0207328276809773 0.0034676048515423 5.600633506652172e-06 +Phospholipid metabolism 14 18 2.72227911875186 0.0064833357861413 5.706310679611651 15.194174757281552 0.9499140430417652 0.282763149469861 3.1039684871946744 2.8053632837701987 1.3505948321648105 0.2868829019946007 0.1011745076435475 1.0 0.3655284832956332 0.1048323445251165 0.0254217837170298 +ER-Golgi transport 21 53 2.705625110136288 0.0068175962071774 13.189320388349516 50.09466019417476 1.0113245710455496 0.4417664900586612 5.844513029144237 4.526971021787617 1.2802141654412966 0.393016134031976 4.862868411517965e-05 0.0005969016459399 0.0075904072731156 0.0007410319848467 0.0001313757083799 +Phospholipid biosynthesis 13 17 2.592094839860319 0.0095393470022857 5.393203883495145 14.228155339805824 0.6697741038582752 0.3412824299901092 3.008201157028892 2.7679482245749822 1.3258103202069491 0.2976917551215703 0.2117287806558738 1.0 1.0 0.2707185745648809 0.0516637732040453 +Sphingolipid metabolism 7 9 2.4680246911694192 0.0135860947912214 5.075242718446602 9.720873786407768 1.0723891387155546 0.1672146303539832 2.245095774833478 1.0461446620678432 1.744521381224598 0.248179764200939 5.051143982139323e-05 1.0 0.1677870330809631 0.0009779431698101 1.8677763344678236e-05 +Lipid transport 7 22 2.332808420892917 0.0196582025128309 5.140776699029126 21.796116504854368 0.7022879686929654 0.35525802853007 2.5598823127228028 3.5727100026626353 1.209238263022456 0.2984698606617377 0.0358299018114851 0.0388410242837302 0.0244837275894334 0.0203556588144228 0.0130614889048102 +Sterol metabolism 12 24 2.2675863586095253 0.0233544298994534 7.606796116504855 25.203883495145632 1.1785484151208083 0.2872927387372206 3.1377365577760563 3.096691699470945 1.2399567569518877 0.3064799172119154 0.0020323862439369 1.0 1.0 0.005869339632186 1.4177363886845684e-05 +Cholesterol metabolism 12 24 2.2675863586095253 0.0233544298994534 7.111650485436893 23.79854368932039 1.169709264926864 0.2871268807807383 2.8890755390042298 2.7173834172675666 1.205315163774447 0.3061468445376054 0.0013805381477328 1.0 1.0 0.0044406378118471 7.272213382369986e-06 +Calcium transport 8 9 2.265747134064996 0.023466869869503 3.7305825242718447 8.240291262135923 0.5020754788348019 0.3462849026834517 2.2148520410126937 1.861210565609195 1.3394131933179945 0.3209721672484884 0.4113165514090738 0.1635258499471353 0.3009165941166509 0.5970702236031354 0.1034478004905659 +Hydrogen ion transport 5 20 2.071598894737404 0.0383028630950914 6.152912621359223 19.560679611650485 0.8019462838912398 0.3170771992837126 2.890966221074556 1.405159537040464 1.2709247974732976 0.29451915785821 0.0009326119272623 0.0096266028600564 0.0002069103237917 0.000812960139445 0.0033472823991884 +Steroid biosynthesis 8 18 2.0379315828566464 0.04155677555403 6.351941747572815 21.094660194174757 1.1936032046421512 0.306057763510231 2.838692628881621 2.6297902443336034 1.071011617665077 0.2981933340003868 0.0007765366578398 1.0 1.0 0.0056128198685199 6.711779371444596e-05 +Steroid metabolism 13 26 2.014308341754504 0.0439771707126233 7.703883495145631 26.439320388349515 1.128083592407629 0.3052190273048834 3.279782799169419 3.1412859163137186 1.216134343451914 0.3162944576553002 0.0044675340848454 1.0 1.0 0.0104048104957299 5.512316207184221e-05 diff --git a/protein_atlas_biological_process/metrics.json b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..673ec6b65f51ff62f4edafcb84b1b1bee83dd83e --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 168, + "title": "Average number of proteins per term", + "value": 29.351190476190474 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6709e75d66ebacc2fe72726f4aca586ee4e10ee3 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e99b901d9d0d35619c6ed3b199993800e4751848 --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,52 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport 0.4623334924124707 4.202399493653804 2.641005184012002e-05 0.0044271185905943 0.0044368887091403 491 O43169,Q86Y82,P98194,Q9NS69,Q8N4H5,Q9H4I9,Q99595,Q9UGP8,P49755,Q9BQE5,O60830,O75396,Q9UDW1,Q9H2D1,P00846,Q00325,Q5JRA6,Q96B49,O95197,Q9H1E5,P41208,Q14849,Q53FT3,Q9BSK2,Q9HCU5,P24390,O14949,Q9Y282,Q9C0H2,P24539,P62072,P51572,P45880,Q9P2W9,O43615,Q9BUR5,O00400,Q9Y3B3,Q9BW27,P21912,O14925,Q9UBX3,Q70HW3,Q676U5,A6NIH7,P61019,Q9Y584,P50416,Q9HD47,Q3ZCQ8,O43592,O15127,O75964,Q8NFH5,Q15363,Q9Y619,O43676,O95721,P21796,O95864,Q9H4A6,Q9Y487,Q9Y3A6,Q13505,O00461,P56134,Q12907,Q96CU9,Q9UJS0,Q92945,Q12769,O43752,Q9Y277,Q96S66,O95070,Q9H2V7,Q96P70,Q15629,P55011,Q9BUN8,Q15907,Q9BVC6,Q86Y39,Q99720,Q15904,Q9NZJ7,P20020,P23786,Q9Y6B6,Q6NUQ1,P12236,Q9Y6C9,P28288,Q9BPX6,Q8WUM4,Q8TEX9,Q16134,P12235,P46379,Q96ES6,Q9HD20,Q96RL7,Q15388,O60831,P53680,O14579,Q9UM00,O43681,P03886,Q9H936,O43731,Q8N5M9,P54709,P06576,O75431,Q9Y3A3,Q12981,Q93050,P51790,Q99523,Q9HAV4,Q9Y2T2,Q8NE01,Q969Q5,Q02978,Q9Y5J9,Q9BTX1,P48739,O95373,Q9H9H4,Q96D46,Q96SU4,P50542,Q8N4V1,Q06787,O15126,Q8TB61,O15118,Q14728,Q6DKK2,Q9HC21,O60220,Q96ST2,Q96RQ1,Q8WVM8,O96000,P36543,P31751,O60784,Q9C0E2,P57740,P55060,O43617,O14617,Q9NRG9,Q8NE86,Q9NR31,Q9P0J0,O75438,Q6NUK1,P61026,Q03518,Q99808,O75381,Q13190,Q9Y5U9,Q96PU8,Q8NFH4,P16615,O15155,O95249,P56385,Q9H3N1,Q96L92,Q13277,Q7L0J3,Q8TDW0,Q9BW72,Q13409,P05141,Q6P4A7,Q9H2C2,O15397,P61916,O43808,Q9H0U3,Q92973,Q9UEU0,Q96HE7,Q8N1F7,Q9P246,P52292,P56962,O14653,Q7Z3B4,Q9P253,P22626,O75306,Q08211,O96008,O95202,O95168,O75027,P05023,P49321,Q99442,Q9H0U4 207 +Ion transport 0.5740128919854763 3.4412691067463896 0.0005789923825905 0.0927152133389868 0.0429477748516245 51 P98194,Q9BVC6,Q15904,P20020,Q9H4I9,P36543,P00846,Q8NE86,Q9BPX6,Q9C0H2,P24539,P45880,Q9P246,Q9UM00,P54709,P06576,O75964,P16615,Q93050,P51790,P21796,P56385,Q9Y487,Q8NE01,P56134,O96008,O95202,P05023,Q9Y277,Q96S66,Q8TDW0,P55011 32 +Translocation 0.5674761371927749 3.3644641209313435 0.0007669245509218 0.1209317650536662 0.0429477748516245 50 Q9NS69,O60220,Q99595,O60830,P41208,P62072,O43615,Q9BW27,O14925,Q8N1F7,O75381,Q9Y584,Q3ZCQ8,Q7Z3B4,Q8NFH4,Q8NFH5,Q9Y5J9,Q9BTX1,Q99442,Q15629 20 +Electron transport 0.5560415074770819 3.17088895919233 0.0015197322377549 0.2254780029810886 0.0638287539857068 44 O43169,Q9P0J0,Q6DKK2,P03886,O75306,O14949,Q86Y39,Q96CU9,O96000,O75438,O43676,Q9UDW1,Q96HE7,Q9H3N1,Q9BW72,Q9H1E5 16 +Respiratory chain 0.610927277613648 3.073493621538011 0.0021156821045764 0.2993950606258035 0.0710869187137692 30 Q9P0J0,O75306,Q6DKK2,P03886,O14949,Q86Y39,Q96CU9,O96000,O75438,O43676,Q9UDW1,Q9BW72 12 +Phospholipid metabolism 0.6478036209994577 2.72227911875186 0.0064833357861413 0.664705682676879 0.0901273816397001 18 Q6P1A2,Q86UL3,Q96N66,O14735,Q7L5N7,O95674,Q9NUQ2,Q9NPH0,Q9UG56,Q8WUK0,Q99943,Q9HBU6,Q8NF37,Q92604 14 +ER-Golgi transport 0.4919538853840052 2.7056251101362876 0.0068175962071774 0.6831346273263175 0.0901273816397001 53 P49755,Q96RQ1,Q9Y6B6,O75396,Q5JRA6,Q9HCU5,Q9NR31,O95197,P24390,Q9Y282,P51572,Q9P2W9,O14579,P61019,P56962,O43731,Q15363,Q12981,O15155,O95249,O95070 21 +Phospholipid biosynthesis 0.6399014010582107 2.592094839860319 0.0095393470022857 0.800172980019161 0.0901273816397001 17 Q6P1A2,Q86UL3,Q96N66,O14735,Q7L5N7,O95674,Q9NUQ2,Q9UG56,Q8WUK0,Q99943,Q9HBU6,Q8NF37,Q92604 13 +Sphingolipid metabolism 0.7808100487995051 2.4680246911694192 0.0135860947912214 0.89955155730589 0.1037483602238726 9 P07602,O95470,P17900,O15269,P04062,Q13510,Q06136 7 +Lipid transport 0.5616368278061687 2.332808420892917 0.0196582025128309 0.9644021910725676 0.1270222316213689 22 Q14849,Q99720,Q9BQE5,Q9H2C2,Q9BUR5,Q96SU4,O15118 7 +Sterol metabolism 0.5380154211953992 2.2675863586095253 0.0233544298994534 0.9811281967786732 0.1314144712692172 24 Q16850,P35610,Q15800,Q9H2C2,P00387,P14324,P04062,Q14739,Q15392,P61916,P37268,O15118 12 +Cholesterol metabolism 0.5380154211953992 2.2675863586095253 0.0233544298994534 0.9811281967786732 0.1314144712692172 24 Q16850,P35610,Q15800,Q9H2C2,P00387,P14324,P04062,Q14739,Q15392,P61916,P37268,O15118 12 +Calcium transport 0.7400197954470404 2.2657471340649957 0.023466869869503 0.9814897214720376 0.1314144712692172 9 Q9BPX6,P98194,Q9H4I9,P20020,O95202,P16615,Q9P246,Q9UM00 8 +Hydrogen ion transport 0.5389476909963938 2.071598894737404 0.0383028630950914 0.998586036233974 0.183853742856439 20 P24539,O75964,Q93050,P00846,Q9Y487 5 +Steroid biosynthesis 0.5460342225607545 2.0379315828566464 0.04155677555403 0.9991998824766952 0.1939316192521401 18 Q16850,Q53GQ0,Q15800,P00387,P14324,Q14739,Q15392,P37268 8 +Steroid metabolism 0.490829831834256 2.0143083417545036 0.0439771707126233 0.9994767994376365 0.1981094383850286 26 Q16850,P35610,Q15800,Q9H2C2,P00387,P14324,P04062,O94905,Q15392,Q14739,P61916,P37268,O15118 13 +Antiport 0.7097175824007286 1.9207327516062096 0.0547654083495929 0.9999222583216464 0.2359125282751697 7 P05141,P12235,O95202,P12236,P51790 5 +Cholesterol biosynthesis 0.558380922544199 1.8727597782474976 0.0611015644713264 0.9999748853351136 0.2444062578853056 14 Q16850,Q15800,P00387,P14324,Q14739,Q15392 6 +Sterol biosynthesis 0.558380922544199 1.8727597782474976 0.0611015644713264 0.9999748853351136 0.2444062578853056 14 Q16850,Q15800,P00387,P14324,Q14739,Q15392 6 +Vision 0.7430839388508811 1.774569318494713 0.0759690270062689 0.9999982807587088 0.2836177008234041 5 O43924,P50897,Q9H6K4 3 +Sensory transduction 0.7430839388508811 1.774569318494713 0.0759690270062689 0.9999982807587088 0.2836177008234041 5 O43924,P50897,Q9H6K4 3 +Unfolded protein response 0.6674791184817052 1.711919510603993 0.0869115025962909 0.9999997676394136 0.3106623922590827 7 Q9BUN8,O95140,Q92575,Q13217,Q15629 5 +Adaptive immunity 0.5795127897468608 1.6879386788452682 0.0914230008170149 0.9999998988951372 0.3134419997123526 11 P10321,Q07021,P04439,P04083,Q9NZ08,Q03518 6 +Symport 0.6717205009887879 1.6455260703132872 0.0998613709378957 0.9999999789147312 0.3226290445685861 6 Q8N697,Q9H936,Q15758,Q00325,P55011 5 +GPI-anchor biosynthesis 0.6591957811469842 1.5842713351296625 0.1131319859858119 0.9999999982609558 0.3388729512448908 6 Q92643,Q5H8A4,Q9H490,Q96S52,O43292 5 +Protein transport 0.4069597492894996 1.5057309353967634 0.1321362591601551 0.999999999954306 0.3580466377242913 252 Q86Y82,Q9NS69,Q9UGP8,Q8N4H5,P49755,Q99595,O60830,O75396,Q5JRA6,Q96B49,Q9HCU5,P41208,Q53FT3,P24390,P62072,P51572,Q9P2W9,O43615,Q9Y3B3,Q9BW27,O14925,Q676U5,A6NIH7,P61019,Q9Y584,Q9HD47,Q3ZCQ8,O15127,Q8NFH5,Q15363,O95721,Q9H4A6,Q9Y3A6,Q13505,Q12907,Q12769,O43752,O95070,Q96P70,Q15629,Q9BUN8,Q15907,Q9Y6B6,Q6NUQ1,Q8WUM4,Q8TEX9,Q9HD20,Q96RL7,Q15388,O60831,O14579,O43731,Q8N5M9,Q9Y2T2,Q969Q5,Q9Y5J9,Q9BTX1,O95373,O60220,O60784,Q9C0E2,Q9NR31,P61026,Q03518,O75381,Q9Y5U9,Q8NFH4,O15155,O95249,Q96L92,O15397,Q92973,Q9UEU0,Q8N1F7,P52292,O14653,Q7Z3B4,Q9P253,O96008,P49321,Q99442,Q9H0U4 82 +Neurotransmitter transport 0.8788676761026996 1.458389093596031 0.1447333251485962 0.999999999996082 0.3671871559561642 2 Q13277 1 +Apoptosis 0.3497674654993982 1.4438452581555248 0.1487825079620761 0.9999999999982347 0.3675803137886587 111 O43464,Q14728,Q9UHX1,P09601,Q9NZJ7,P31751,Q07021,P12236,Q5J8M3,Q9H8M7,O60566,O95197,Q9P0J0,Q9H3K2,Q8WUM4,O95470,Q9BXK5,P51572,P46379,Q9H2J4,O14737,P61289,Q9NR28,Q96HE7,Q01085,Q07820,O60313,Q96A26,Q12981,Q6NUQ4,P21796,Q15041,Q9UDX5,Q96TC7,Q03164,Q9NQ88,Q05655,Q96KA5,Q9Y371,O95831,P05067 41 +Peroxisome biogenesis 0.7885375494071223 1.4351900266353588 0.1512329548492961 0.9999999999989124 0.368219368328721 4 O75192,P40855,Q9Y5Y5 3 +Phenylalanine catabolism 0.8469387755101948 1.3227520722085748 0.1859178404996173 0.999999999999999 0.4220837459991313 2 O43708 1 +Tyrosine catabolism 0.8469387755101948 1.3227520722085748 0.1859178404996173 0.999999999999999 0.4220837459991313 2 O43708 1 +Leukotriene biosynthesis 0.8294930875575883 1.2488669852792436 0.2117137286768264 1.0 0.4619208625676214 2 P09960 1 +Lipid metabolism 0.3421553024971544 1.1981284358870743 0.2308670201559914 1.0 0.4760449005038023 127 Q16850,Q96G23,Q86SQ9,Q99735,P07602,P23786,Q96N66,Q8WUK0,Q9H2C2,Q9UG56,Q9H6V9,P14324,Q15392,Q06136,P61916,Q8NF37,A1L0T0,Q9NZ01,O15254,O95470,Q8NCC3,P17900,O95674,O15269,P04062,Q13510,Q8NBQ5,P51648,P50416,Q53GQ0,P35610,P09960,Q9NUQ2,Q9UKU0,P00387,Q9NPH0,Q15067,O94905,P37268,Q9P035,Q8NCG7,Q15800,Q8NHP8,Q9NP80,Q14739,Q9HBU6,Q8IVS2,Q16836,O15118 49 +ATP synthesis 0.5508645389804453 1.1388881969797762 0.2547497891535257 1.0 0.5035054656210862 8 P56134,P06576,O75964,P00846,P56385 5 +Autophagy 0.3573750931520139 1.1191049716408406 0.2630953591227192 1.0 0.5080462107197335 38 P56962,Q676U5,Q8IXJ6,Q969Q5,Q9UHD9,Q8NEB9,Q9BXS4,Q9H0U4,Q9Y6I9,Q96GC9,O95721,Q9Y371,Q9P253 13 +Sodium/potassium transport 0.7653061224489806 0.9805691842292852 0.3268052368765031 1.0 0.5840774446303459 2 P05023 1 +Notch signaling pathway 0.5185054655849906 0.9684496512302294 0.3328198527451227 1.0 0.5885656343282171 8 Q92542,P05067 2 +Potassium transport 0.7655581165623975 0.9321368159600004 0.3512658237363411 1.0 0.5949228165096822 3 P05023,P55011 2 +Sodium transport 0.7655581165623975 0.9321368159600004 0.3512658237363411 1.0 0.5949228165096822 3 P05023,P55011 2 +Amino-acid transport 0.6477680254782721 0.8489980544394117 0.3958823748720843 1.0 0.6215723269019642 4 P08195,Q6P4A7 2 +Oogenesis 0.7396109529642829 0.8340002849263887 0.4042808232880572 1.0 0.6231117276366387 3 Q9Y5A9 1 +Peptide transport 0.7264647794601461 0.8232604858185173 0.4103598789635188 1.0 0.6267314515079195 2 Q03518 1 +Sugar transport 0.7093482554312059 0.7558509768752056 0.4497385490312335 1.0 0.6547249853274045 2 P31751 1 +Cell adhesion 0.2946701001985998 0.3515902545193063 0.7251455749070408 1.0 0.8519192768138661 28 P05067,Q96GC9 2 +Methionine biosynthesis 0.5901909150757095 0.343005028766124 0.7315946770016939 1.0 0.8532315290320347 2 Q99707 1 +Isoprene biosynthesis 0.5888362252273598 0.3270419490499797 0.7436361574196773 1.0 0.8556909208664779 3 Q5T2R2 1 +RNA-mediated gene silencing 0.3086921406064937 0.3079350398806836 0.7581317624699708 1.0 0.8605820006415885 19 Q9HCE1,Q08211,Q9BWF3,Q92600,Q06787,Q9HAV4,O75569 7 +Zinc transport 0.5503620803159992 0.2376781459614154 0.8121307350005764 1.0 0.9032764132229032 2 Q8NEW0 1 +Prostaglandin metabolism 0.514981890023036 0.1503617351563209 0.8804792289235166 1.0 0.9605227951892908 3 Q9H7Z7,Q14914 2 +Viral RNA replication 0.489137590520081 0.1181113004621162 0.9059794696549528 1.0 0.9756701980899491 2 Q15365 1 +Glycogen biosynthesis 0.3120789357378142 0.0155396821370787 0.9876016265418088 1.0 1.0 5 P46976,P31751 2 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7279990b683e753c1fafa4564c26ac916df93c6a --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Bile acid catabolism", "Biological rhythms", "Biomineralization", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Carnitine biosynthesis", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Cysteine biosynthesis", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyridoxine biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT2", "ALDH18A1", "ALDH3A2", "ALDOA", "ALDOC", "ALKBH5", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANLN", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "API5", "APOL2", "APOO", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP2", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARL8A", "ARMC10", "ARMT1", "ARV1", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATG13", "ATG16L1", "ATG7", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "AUP1", "AURKA", "BABAM1", "BABAM2", "BAG3", "BAG6", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BET1", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOP1", "BRD2", "BRIX1", "BRPF1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "CACYBP", "CAD", "CAMK2G", "CAND1", "CANX", "CAPRIN1", "CARM1", "CARS", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC86", "CCDC88A", "CCDC93", "CCDC94", "CCNB1", "CCNB2", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC27", "CDC34", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPU", "CENPV", "CEP55", "CERS1", "CERS2", "CETN2", "CFL1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST12", "CHST14", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "COASY", "COMMD2", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPZ1", "COQ5", "COQ8A", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF2", "CSTF3", "CTBP2", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CWC15", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCPS", "DCTD", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DEGS1", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIS3", "DKC1", "DLAT", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJB1", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPYSL2", "DSC2", "DSG2", "DST", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP2", "EMC4", "EMG1", "EML4", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERCC2", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM162A", "FAM208A", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXC1", "FOXRED1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCC2", "GCFC2", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGT7", "GHITM", "GINS3", "GINS4", "GLRX", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPI", "GPKOW", "GPR89B", "GRB2", "GRIPAP1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP4", "GYG1", "GYS1", "H2AFX", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD2A", "HIKESHI", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK3", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INTS13", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD5", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIF11", "KIF20A", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "LAMB1", "LAMC1", "LAMP1", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAD1L1", "MAGT1", "MAP1S", "MAPK1", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED16", "MED24", "MED25", "MESD", "METTL1", "METTL14", "MFAP1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MIA3", "MIB1", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MLEC", "MMGT1", "MMS19", "MOB4", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MRC2", "MRE11", "MRPL58", "MRPS27", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NACC1", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCK2", "NCKAP1", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEK9", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIP7", "NIPBL", "NKRF", "NLE1", "NMD3", "NME1", "NME2", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NR2F2", "NSA2", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSRP1", "NSUN2", "NT5C2", "NT5C3B", "NTHL1", "NUCKS1", "NUDC", "NUDCD1", "NUDT16", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PANK4", "PAPOLA", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PAWR", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCLAF", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDS5A", "PDS5B", "PDSS1", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX11A", "PEX14", "PEX16", "PEX19", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3C3", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POP1", "POP4", "PPAT", "PPHLN1", "PPID", "PPIF", "PPIH", "PPIL1", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKCD", "PRKDC", "PRKRA", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTK7", "PTPMT1", "PTPN23", "PTRH2", "PUF60", "PUM1", "PURA", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RANGRF", "RAPGEF2", "RARS", "RBBP5", "RBBP6", "RBM10", "RBM14", "RBM15", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCC2", "RCL1", "REEP3", "REEP4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RIF1", "RINT1", "RMDN3", "RMND1", "RNASET2", "RNF14", "RNF20", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF2", "RPL10", "RPL13A", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP36", "RRP8", "RRS1", "RSF1", "RTCB", "RTF1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDF4", "SDHA", "SDHB", "SEC16A", "SEC22B", "SEC23A", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC15A4", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG8", "SMN1*", "SMNDC1", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SON", "SORT1", "SPAG5", "SPATA5", "SPC24", "SPC25", "SPEN", "SPNS1", "SPOUT1", "SPTLC1", "SPTLC2", "SRCAP", "SRM", "SRPK1", "SRPK2", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STIM2", "STK26", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "TACC3", "TACO1", "TAF6L", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBCB", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TDRKH", "TECR", "TEFM", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TK1", "TLN1", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM14C", "TMEM214", "TMEM59", "TMLHE", "TMX1", "TMX4", "TNPO1", "TNPO3", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TP53", "TP53BP1", "TPI1", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT6", "TRMU", "TROVE2", "TSFM", "TSG101", "TSNAX", "TSR1", "TSR2", "TTC19", "TTC26", "TTC4", "TTLL12", "TTYH3", "TUBB2B", "TUFM", "TWNK", "TXLNA", "TXLNG", "TXNL1", "TXNRD1", "TYMS", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3C", "UBE4A", "UBE4B", "UBQLN2", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VMP1", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WASHC3", "WBP11", "WDR12", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR5", "WDR6", "WDR61", "WDR75", "WIPI2", "WLS", "WRAP53", "WTAP", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS4", "YIF1A", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "ZC3H11A", "ZC3H13", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZMYM2", "ZNF207", "ZNF24", "ZNF281", "ZNF326", "ZNF593", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAAS", "ABCB7", "ABCD3", "ACOX1", "ACOX3", "ACP6", "ACSL6", "AGPAT1", "AGPAT5", "AIFM1", "AKT2", "ALDH3A2", "ANXA1", "AP2S1", "AP3D1", "AP3M1", "APOL2", "APOO", "APP", "ARL6IP1", "ARV1", "ASAH1", "ASNA1", "ATG16L1", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1E1", "BAG6", "BCAP31", "BCL2L13", "BET1", "BNIP1", "BUB1B", "C1QBP", "CDIPT", "CDS2", "CERS2", "CETN2", "CLCC1", "CLCN3", "CLPTM1L", "CNNM3", "CNOT9", "COPE", "CPT1A", "CPT2", "CSE1L", "CYB5B", "CYB5R3", "CYP51A1", "DAGLB", "DERL1", "DHCR24", "DHDDS", "DHX9", "DIABLO", "DNAJC3", "DYNC1I2", "EMC4", "ERAP1", "ERGIC2", "ERGIC3", "ERLIN2", "ERO1A", "ETFDH", "ETNK1", "FADS2", "FAM162A", "FDFT1", "FDPS", "FMR1", "FOXRED1", "GBA", "GHITM", "GM2A", "GOLIM4", "GOLPH3", "GOSR1", "GOSR2", "GPAA1", "GPAT4", "GSTZ1", "GYG1", "HACD3", "HADH", "HIGD2A", "HIKESHI", "HLA-A", "HLA-C", "HMOX1", "HNRNPA2B1", "HSD17B11", "HSD17B12", "HTRA2", "IER3IP1", "ILVBL", "IPO4", "IPO7", "IPO8", "IPO9", "IWS1", "JAGN1", "KDELR1", "KDELR3", "KDSR", "KHSRP", "KMT2A", "KPNA2", "LBR", "LDAH", "LETM1", "LMAN2", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRRC8C", "LTA4H", "MAGT1", "MBOAT7", "MCAT", "MCL1", "MCU", "MFN2", "MFSD10", "MFSD3", "MGST2", "MIA3", "MICU1", "MINDY3", "MMGT1", "MOB4", "MOV10", "MSMO1", "MTCH1", "MTCH2", "MTFP1", "MTR", "MTX1", "MTX2", "NASP", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFS2", "NMD3", "NPC1", "NPC2", "NUP107", "NUP160", "NUP35", "NUP37", "NUP54", "NUP85", "NUP93", "OPA1", "OPA3", "OSBPL9", "PCBP1", "PDCD5", "PDCD6IP", "PDCL3", "PDE6D", "PDSS1", "PEX11A", "PEX14", "PEX16", "PEX19", "PEX5", "PIGG", "PIGK", "PIGS", "PIGU", "PIK3C3", "PISD", "PITPNB", "PLA2G15", "PLBD2", "PNPLA8", "PPT1", "PRAF2", "PREB", "PRKCD", "PRKRA", "PSAP", "PSME3", "PTGES2", "PTGR1", "PTPMT1", "PUF60", "QKI", "RAB10", "RAB11B", "RAB1B", "RAB24", "RAB2A", "RANGRF", "RBM4", "RINT1", "RMDN3", "RTN3", "SAR1A", "SAR1B", "SCAMP1", "SCAMP2", "SCFD1", "SDHB", "SEC22B", "SEC62", "SEC63", "SFXN4", "SGPL1", "SH3GLB1", "SIGMAR1", "SIRT2", "SLC12A2", "SLC15A4", "SLC1A5", "SLC25A10", "SLC25A11", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC29A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC3A2", "SMDT1", "SNAP29", "SNX27", "SOAT1", "SORT1", "SPNS1", "SPTLC1", "STARD3", "STIM2", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "SV2A", "TAP1", "TECR", "TEX264", "TIAL1", "TIGAR", "TIMM10", "TIMM17A", 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sha256:8329ea34135c934f471945461d7ed770750160817354431b18d06dae6f1bf16f +size 73294 diff --git a/protein_atlas_disease_involvement/df_merge.tsv b/protein_atlas_disease_involvement/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..85daa376dfbfc64d408d502d70a481da51166659 --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Primary mitochondrial disease 28 93 3.675338463178132 0.0002375342973843 27.53640776699029 92.44660194174756 0.9978626953080288 0.3665723479658412 11.863754653333944 10.66022291187525 1.7959996823414457 0.3879563837717744 4.815239705520221e-06 0.0082948362693521 0.0001972156007735 1.2536729787029491e-05 1.7428660531986743e-09 +Gangliosidosis 3 5 2.3522579864934685 0.0186598279840759 2.8567961165048543 4.902912621359223 0.2158556094961241 0.1574800557957235 1.2213224676890235 0.2960767122713962 1.9039254823866087 0.2239345049259472 9.814384973019042e-06 1.0 1.0 0.0055694485300755 2.661109756617399e-05 +Congenital disorder of glycosylation 10 17 2.2513314031594533 0.0243645552545166 5.618932038834951 18.325242718446603 0.4013656328493284 0.4500757016048167 2.8520016519219875 3.440343696044481 1.1296344785223882 0.3186521023843959 0.006611630235938 1.0 0.3530974878629287 0.0230341265569123 0.0056200963406339 +Mucopolysaccharidosis 3 5 2.2434387026019507 0.0248685384900835 2.254854368932039 4.752427184466019 0.4843930061917075 0.2034155563537636 0.9831595235232706 0.7286567852681505 1.626107445717624 0.2463507210616131 0.0005400376352805 1.0 1.0 0.2365379696877526 0.00138858926748 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bf1c118cb4e57b31ef3a5ace79d53bc4c0a19f92 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 111, + "title": "Average number of proteins per term", + "value": 21.62162162162162 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1ad843e13277f9f8418c025c6deb7859ca50f5ee --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1b43f1bce8152b08afc1932d731f455997df463e --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,39 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Primary mitochondrial disease 0.514285645238601 3.675338463178132 0.0002375342973843 0.0260248012473305 0.0263663070096661 93 Q6DKK2,Q86Y39,Q9Y2R0,Q6P4A7,Q9BUB7,Q07021,P00846,Q7KZN9,O75880,P51530,Q9P0J0,O14949,Q53H12,P12235,O60783,Q96I36,Q9BW92,P13073,Q9UBX3,Q70HW3,P03886,Q5T2R2,Q9Y584,O60313,O43676,O75306,Q96CU9,Q5XKP0 28 +Gangliosidosis 0.8742101039206799 2.3522579864934685 0.0186598279840759 0.8764129132573045 0.23013787847027 5 P07602,P17900,P06865 3 +Congenital disorder of glycosylation 0.587713358355093 2.2513314031594533 0.0243645552545166 0.9352976211065782 0.2509461611272064 17 Q9HC07,Q9H0U3,P51571,O60762,P15291,Q9BV10,Q8N511,Q10471,Q9BT22,P46977 10 +Mucopolysaccharidosis 0.8488878843725929 2.2434387026019507 0.0248685384900835 0.9389041482470024 0.2509461611272064 5 P15586,P16278,P08236 3 +Leber hereditary optic neuropathy 0.9361421988150006 1.701622817913461 0.0888260972679182 0.999967210013102 0.5844035096553832 2 P00846 1 +Gaucher disease 0.9134298880842664 1.6052928798803614 0.108429365373686 0.9999970671564484 0.6173307828854326 2 P04062 1 +Ehlers-Danlos syndrome 0.8174245092761622 1.555599877637618 0.1198032678468739 0.9999992947347984 0.6173307828854326 4 Q9NWM8,Q8NCH0 2 +Neuronal ceroid lipofuscinosis 0.9074744813961088 1.4850920047945004 0.1375194537251944 0.999999926180143 0.6173307828854326 3 P50897,O75503 2 +Cataract 0.4219772723138176 1.4769421050121243 0.1396911570940269 0.9999999441996468 0.6173307828854326 28 P08670,O76024,Q9H6K4,Q15800,Q9UG56,O00400 6 +Alzheimer disease 0.6651559790564621 1.416275565892846 0.1566948388541758 0.9999999939143333 0.620246894569105 5 P05067 1 +Niemann-Pick disease 0.8647136273864378 1.398221754495759 0.1620464859685049 0.999999996997992 0.620246894569105 2 O15118 1 +Peroxisome biogenesis disorder 0.7513175230566687 1.279386128123045 0.2007611163223517 0.9999999999842564 0.674251231346311 4 P40855,O75381,Q9Y5Y5 3 +Zellweger syndrome 0.7513175230566687 1.279386128123045 0.2007611163223517 0.9999999999842564 0.674251231346311 4 P40855,O75381,Q9Y5Y5 3 +Dystonia 0.5790318426035311 1.1862486309173237 0.2355241263756173 0.9999999999998868 0.7168552479038786 6 O75569,P51572,P04350,O60220 4 +Amyloidosis 0.7043216104744633 1.0826931305299332 0.2789446541509681 0.9999999999999998 0.7168552479038786 4 P05067 1 +Progressive external ophthalmoplegia 0.7014169180309393 1.0705771344627648 0.2843596092314824 1.0 0.7168552479038786 4 P51530,P12235 2 +Retinitis pigmentosa 0.4289935992365621 1.0407213163450546 0.298004907104761 1.0 0.7168552479038786 15 P00846 1 +Amyotrophic lateral sclerosis 0.4371226343348934 1.0204649201921725 0.3075080181611236 1.0 0.7168552479038786 13 Q99720,P35637 2 +Leigh syndrome 0.4783430134210932 0.9821729753557936 0.3260146388893872 1.0 0.7168552479038786 10 P00846 1 +Lissencephaly 0.4771221627144743 0.9749455051288094 0.3295872921756466 1.0 0.7168552479038786 10 Q6ZXV5,O43505,Q9BSJ2 3 +Dystroglycanopathy 0.6708407443168358 0.9436625189591756 0.3453421331003212 1.0 0.7168552479038786 4 O43505 1 +Rhizomelic chondrodysplasia punctata 0.750822909809086 0.921308212570794 0.3568895346078118 1.0 0.7202679698448565 2 O00116 1 +Ichthyosis 0.4996987402445895 0.8695586052021206 0.3845416678615141 1.0 0.7234597480106452 8 P51648 1 +Leukodystrophy 0.390792012516892 0.8499929434860175 0.3953290094656223 1.0 0.7313586675114012 17 P07602,Q53FT3,Q9NR50 3 +Craniosynostosis 0.5970340810541885 0.6465994790950255 0.5178911952405014 1.0 0.7622182619942165 4 P16435 1 +Congenital muscular dystrophy 0.4868244201122008 0.5942588462197227 0.5523389993963788 1.0 0.7622182619942165 5 O43505 1 +Proto-oncogene 0.3014245448338083 0.5493671741178964 0.5827534965876429 1.0 0.7700671204908137 38 Q03164,O14965,O96028,Q16204,Q01105,Q15154,Q8WY22,Q01844,Q92733,Q06136,Q92804,Q96T37,P35637 13 +FDA approved drug targets 0.2831793365892258 0.4560778938174509 0.6483339660184182 1.0 0.8351881056979495 114 Q16850,Q99720,P05141,P23786,P12236,P14324,P49356,P62942,P49721,P12235,Q14534,P03886,P16615,P21964,P00374,P38435,Q7L0J3,Q05655,P04083,Q8N0U8,Q16836,Q13423,P05067 23 +Diabetes mellitus 0.3623889592248727 0.4425576964545016 0.6580856891066391 1.0 0.8351881056979495 12 Q9Y5U9,P03886,O76024,P31751,Q5VV42,Q13217 6 +Parkinson disease 0.4109835807853188 0.4185252343989835 0.6755631406817875 1.0 0.8358793820151674 8 Q96A57 1 +Hereditary spastic paraplegia 0.342383235217772 0.4155490176984527 0.6777400394717574 1.0 0.8358793820151674 14 O00400,O94905 2 +Parkinsonism 0.3413732248788549 0.2604326290404677 0.7945300767230696 1.0 0.9586178099593556 11 Q96A57 1 +Emery-Dreifuss muscular dystrophy 0.39576979340948 0.2360114872280027 0.8134237564238849 1.0 0.9593293863230372 5 P50402 1 +Congenital myasthenic syndrome 0.5429406787033599 0.2097743808730483 0.8338437692687444 1.0 0.9641318582169855 3 Q4J6C6 1 +Deafness 0.2588333598666703 0.1651644395561931 0.8688145539399321 1.0 0.9942104689415718 49 O76024,O60220,Q16740,O60313,Q96RR1,Q9UG56,Q15067,O00400,Q9NR28,Q9NWM8 10 +Holoprosencephaly 0.4855167873601074 0.1126972007596941 0.9102706205824598 1.0 1.0 2 A5YKK6 1 +Spinocerebellar ataxia 0.3060705423956549 0.0525844808693257 0.9580629823342732 1.0 1.0 10 Q8IV08 1 +Obesity 0.4346394468225266 0.0338267734737266 0.9730152860141954 1.0 1.0 3 Q9C0B1,Q9Y4W2 2 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..41ea3329234d84911b9ede29840be0efa49cd14c --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Peters anomaly", "Phenylketonuria", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "ABCB1", "ABCB7", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AKAP12", "AKAP9", "AKR1B1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG8", "ANAPC1", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA7", "AP1B1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APOL2", "APP", "APPL1", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARPC1B", "ARV1", "ASAH1", "ASCC1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATG13", "ATIC", "ATL3", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATPAF2", "ATXN10", "ATXN2", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCAS3", "BCLAF1", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BMS1", "BRI3BP", "BRPF1", "BUB1B", "BUD23", "C19orf70", "C1QBP", "CAD", "CALM3", "CALR", "CAMK2G", "CANX", "CAPN1", "CARM1", "CARS", "CASK", "CAST", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC6", "CCDC88A", "CCNB1", "CCNB2", "CCT5", "CDC27", "CDC34", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHMP1A", "CHMP4B", "CHST14", "CISD2", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNOT1", "CNOT3", "COA3", "COA7", "COASY", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTDP1", "CTH", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CWF19L1", "CYB5R3", "CYC1", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBN1", "DBT", "DCPS", "DCTN1", "DCUN1D1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEGS1", "DEK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIS3", "DKC1", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJB1", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DSC2", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "EPB41", "EPB41L3", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERCC2", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC9", "EXTL3", "EZR", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FAM3C", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FNTB", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GCLM", "GDAP1", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPB", "GMPS", "GNAI1", "GNAI3", "GNS", "GOLGA5", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPI", "GPRASP2", "GRB2", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2I", "GUSB", "GYG1", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HEXA", "HEXB", "HIBCH", "HIKESHI", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOOK3", "HPRT1", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFT27", "IGBP1", "IGF2R", "IKBKB", "ILF3", "ILK", "IMPAD1", "IMPDH2", "INF2", "INTS1", "IPO7", "IRF2BPL", "IRS4", "ITGB1", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDM5A", "KDSR", "KIF11", "KIF1A", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KLC2", "KMT2A", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LGMN", "LIPA", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRPPRC", "LSS", "LTA4H", "M6PR", "MACF1", "MAD1L1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAP4", "MAPK1", "MAPK3", "MAPKAPK2", "MARS", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED25", "MESD", "METTL14", "MFN2", "MGME1", "MIB1", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MOGS", "MORC2", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS14", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MYH10", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NACC1", "NAGLU", "NAMPT", "NANS", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPH", "NCKIPSD", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NF1", "NFKBIE", "NHLRC2", "NHP2", "NIPBL", "NME1", "NME2", "NNT", "NONO", "NOP56", "NOTCH2", "NPC1", "NPC2", "NPM1", "NR2F2", "NSD2", "NSDHL", "NSMCE2", "NSUN2", "NT5C2", "NTHL1", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OMA1", "OPA1", "OPA3", "OSGEP", "OSTM1", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B2", "PARD3", "PARK7", "PARN", "PARP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDCD4", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDSS1", "PDXK", "PEPD", "PEX14", "PEX16", "PEX19", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PINX1", "PISD", "PKM", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PSPH", "PTDSS1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PURA", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "RAB10", "RAB11B", "RAB18", "RAB23", "RAB3GAP2", "RAB7A", "RAB8A", "RABEP1", "RAC1", "RAD21", "RAD23B", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBMX", "RDH11", "RDX", "REPS1", "RFC1", "RFC2", "RHEB", "RHOA", "RINT1", "RMND1", "RNASEH2A", "RNASET2", "ROCK1", "ROCK2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS26", "RPS28", "RPS29", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRM1", "RRM2", "RTN4IP1", "SAMHD1", "SAR1B", "SARS", "SART1", "SASS6", "SBDS", "SCARB2", "SCO1", "SCO2", "SCRIB", "SDHA", "SDHB", "SEC23A", "SEC31A", "SEC61A1", "SEC63", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SHOC2", "SIGMAR1", "SIN3A", "SIRT2", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A9", "SLC33A1", "SLC3A2", "SMARCA4", "SMARCAD1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SNAP29", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOAT1", "SOD2", "SON", "SORD", "SPART", "SPATA5", "SPEN", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRP54", "SRP72", "SRSF3", "SSB", "SSR4", "STAG2", "STAMBP", "STARD3", "STAT1", "STAT3", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STX5", "SUCLA2", "SUCLG1", "SUZ12", "SV2A", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBCD", "TBCE", "TBL2", "TCEA1", "TCOF1", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM17A", "TIMM22", "TIMM50", "TIMM8A", "TIMMDC1", "TJP2", "TK1", "TKT", "TMCO1", "TMEM165", "TMEM199", "TMEM230", "TMEM43", "TMEM70", "TMLHE", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM3", "TPM4", "TPP1", "TPR", "TPX2", "TRAPPC11", "TRIM25", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMU", "TSFM", "TSG101", "TSR2", "TTC19", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWNK", "TXLNA", "TXNRD1", "TYMS", "UBA1", "UBA5", "UBE2N", "UBE2T", "UBQLN2", "UBQLN4", "UBR5", "UBTF", "UFC1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNG", "UPF3B", "UQCC2", "UQCRB", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP9X", "UTP4", "VAC14", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS13A", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS51", "VPS53", "VRK1", "WARS", "WBP2", "WDR1", "WDR36", "WDR45B", "WDR5", "WFS1", "WIPI2", "WNK1", "WRAP53", "XPNPEP3", "XPO1", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YES1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H14", "ZCCHC8", "ZMPSTE24", "ZMYM2"], "leading_proteins": ["ACOX1", "AGK", "AGPS", "AKT2", "ALDH3A2", "ALG1", "ALG12", "ANXA1", "APP", "ATP2A2", "ATP6", "AURKA", "B4GALT1", "B4GAT1", "BCAP31", "BRI3BP", "C19orf70", "C1QBP", 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a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..bb426eec77717082dbdd42e761f7c532207ecd2a --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bd84b76d07cc3f54367e0b9ab869ce92e3197203f6c1ba487394067cb647b581 +size 74727 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..14891663673a9ff057d2d3a701eb4d8681b63403 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Receptor 12 33 3.3178066211636525 0.0009072727401928 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.23894148793945 0.3389463545940903 0.6974301549747458 0.2604813942142019 0.4431164022439814 +Host cell receptor for virus entry 4 13 2.167094921374672 0.0302276170962569 4.509708737864078 15.157766990291265 0.7214109752050332 0.2527966464979699 2.499010078306418 1.9009100692398744 1.5211756979359785 0.2791170769282048 0.0732969355710917 1.0 1.0 0.6437372861060551 0.0516637732040453 +Glycosidase 9 19 2.005370031570411 0.0449235030544206 7.798543689320389 18.135922330097088 0.5112745472223946 0.1951515073440806 2.9064203812520417 1.9684331341643595 1.9501681029822375 0.2619382904734375 0.0052718908349527 1.0 1.0 0.2797556636969028 0.0043384264527958 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..539056de95d28ed5ec46683accb7f11ccefcc47c --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 96, + "title": "Average number of proteins per term", + "value": 36.979166666666664 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0e9a8742f33092b14dca8cd8a7dc11a84a760b31 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4cb96789afd6ca42df777248a768bf867ec806a0 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,19 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Receptor 0.6273111954707088 3.3178066211636525 0.0009072727401928 0.0834491384973502 0.0290327276861717 33 Q9Y5M8,Q9NS69,P24390,P11279,Q99720,O43731,O00264,Q14108,O15173,Q14739,Q8WTV0,O15118 12 +Host cell receptor for virus entry 0.6135576044341472 2.167094921374672 0.0302276170962569 0.9474827512031864 0.2072750886600479 13 Q14108,Q8WTV0,P11279,O15118 4 +Glycosidase 0.5357026580944884 2.005370031570411 0.0449235030544206 0.9878755191404684 0.2395920162902432 19 P06280,P16278,P04066,P10253,P04062,P06865,Q9BTY2,P08236,P54802 9 +Metalloprotease 0.460213718601211 1.8064559680502923 0.0708471460585034 0.9991362901779955 0.2833885842340136 28 P55786,Q7Z2K6,P09960,Q5JRX3,P42892,Q96E52,Q9UIQ6,Q9NZ08,O75844 9 +Porin 0.855480120657689 1.7130918097875782 0.0866956505604754 0.9998343885017174 0.3329112981522257 4 P45880,P21796 2 +Glycosyltransferase 0.4332252761386695 1.6723879954469831 0.0944478377433373 0.9999269377061288 0.3368581175687816 32 O43505,P43490,Q96L58,Q10472,Q13126,O43909,Q9BV10,P04062,P15291,Q10471,Q9BT22,P46977 12 +Monooxygenase 0.916035561409281 1.5186311459567017 0.1288553667785863 0.9999982271765684 0.4123371736914762 3 Q6UW02,Q9BU89 2 +Carboxypeptidase 0.5818692723870627 1.2766176674514302 0.201737261335789 0.9999999995963524 0.4946634767397334 7 P16870,Q9HB40,P42785,P10619,Q9H3G5 5 +Ion channel 0.5509683091534768 1.264335084343332 0.2061097819748889 0.9999999997617662 0.4946634767397334 9 Q9BVC6,Q9C0H2,Q96S66,Q8TDW0,Q9UM00 5 +Translocase 0.4215224428963294 1.2216750616593164 0.2218305306245349 0.9999999999650762 0.5194080717062282 21 Q8NB49,O75306,P98194,P03886,P20020,P00403,P06576,P16615,Q9HD20,P05023,P08183,Q8NBU5,Q03518,Q13423 14 +Serine protease 0.5509600014458433 1.139390467097569 0.2545403302616773 0.999999999999434 0.5268270139568072 8 Q16740,O14773,Q4J6C6 3 +Protease 0.3137474477885591 1.1183594468001488 0.2634135069784036 0.9999999999998208 0.5268270139568072 77 O43464,Q7Z2K6,Q99538,Q96E52,Q9UIQ6,O14773,P67812,O75844,Q99797,Q15005,Q4J6C6,Q96K76,Q9HB40,P09960,P42892,P10619,Q9NZ08,Q5JRX3,Q8TCT8,P28072,Q92643,Q16740,Q96FW1,P55786,Q9H3G5,Q8TCT9 26 +Guanine-nucleotide releasing factor 0.4136283728023056 0.932368280559608 0.3511462314690625 1.0 0.6242599670561112 15 P80303,Q9HD47 2 +Calcium channel 0.738314680710995 0.8706793827638628 0.3839292388245059 1.0 0.6323713272687841 2 Q9UM00 1 +Methyltransferase 0.2982607499121756 0.4621566968709204 0.6439689541984337 1.0 0.835419183824995 35 Q9BV86,P21964,Q9UBP6,O60725 4 +Acyltransferase 0.2943468762607609 0.4413625186100739 0.6589505723406339 1.0 0.8434567325960114 36 P50416,Q86UL3,P11182,Q9BWD1,P35610,Q8NCC3,P23786,Q96N66,Q7L5N7,Q9NUQ2,O95251,O15269,Q99943,O15270,Q9UJ14,Q8NF37,Q92604 17 +Rotamase 0.2957822528655815 0.246242417310423 0.8054945819463675 1.0 0.927679016166708 21 Q9Y680,P62942,O95302 3 +Aminopeptidase 0.3371533578419615 0.2382088167507828 0.8117191391458696 1.0 0.927679016166708 11 Q9NZ08,Q9UIQ6 2 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c24cc47ea3b83a418390adee5e36bf8b12c7825d --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG8", "ALKBH5", "ANKHD1", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APEH", "APEX1", "APP", "APRT", "AQR", "ARFGAP1", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATPAF2", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAZ1B", "BAZ2A", "BCLAF1", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BPNT1", "BRD2", "BRPF1", "BSG", "BTF3", "BUB1", "BUB1B", "BUD23", "BZW1", "BZW2", "C12orf43", "CAD", "CALD1", "CALR", "CAMK2D", "CAMK2G", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX3", "CCAR1", "CCAR2", "CCDC47", "CCDC88A", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC34", "CDC37", "CDC42", "CDC5L", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPU", "CEP55", "CERS1", "CERS2", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHKA", "CHMP1A", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COPA", "COPS5", "COQ5", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX2", "COX4I1", "CPD", "CPE", "CPNE1", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP2", "CTDP1", "CTH", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCPS", "DCTD", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "ERAL1", "ERAP1", "ERCC2", "ERCC6L", "ERMP1", "ERO1A", "ERP44", "ESD", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXTL3", "F11R", "FADS2", "FAH", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FNTB", "FOXC1", "FOXRED1", "FOXRED2", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCN1", "GDI1", "GDI2", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGT7", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNPDA1", "GNPNAT1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPI", "GPKOW", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HEXA", "HEXB", "HIBADH", "HIBCH", "HIF1AN", "HINT3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTRA2", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS11", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KLC1", "KLC2", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "L3HYPDH", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LEMD3", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPAP1", "LRPPRC", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAGED2", "MAN1A2", "MAN2B1", "MANBA", "MAP1S", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MARCH5", "MARCKS", "MARS", "MAT2A", "MATR3", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED24", "MED25", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL14", "METTL7B", "MFN1", "MFN2", "MGEA5", "MGME1", "MGST2", "MGST3", "MIB1", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL3", "MRPL37", "MRPL39", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS14", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MYBBP1A", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCBP2", "NCBP3", "NCL", "NCOA5", "ND1", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4L", "NEK9", "NELFCD", "NELFE", "NES", "NF1", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSRP1", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OXCT1", "OXSR1", "P3H1", "P3H3", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCMT1", "PCNA", "PCYOX1", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDSS1", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PIGG", "PIGK", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR2H", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS2", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRP1B", "RRP7A", "RRP8", "RSF1", "RTCA", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", 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-0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 311 570 10.835016609257863 2.3492277757481728e-27 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 2.284314003420047e-50 4.2508318356866075e-10 4.5591815617747855e-18 3.755003149693614e-44 4.687849802724e-54 +Transporters 164 372 3.5196456155330824 0.0004321237569366 108.9004854368932 367.3009708737864 1.469396346451591 0.4764419032567517 40.40141182476491 35.10022679965902 2.352674986871393 0.4490473364946538 2.631548967267003e-22 0.0318727848003628 5.67823517839768e-06 7.449096009260213e-14 2.9817000106405223e-30 +Predicted secreted proteins 20 48 2.595772423244122 0.0094378552883225 15.29368932038835 51.737864077669904 1.393291060716792 0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 0.142161483200443 0.7310572648855516 0.1168897576974505 0.0627859134401757 0.1624494062352181 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f7faed085de28c14053102ddc992e7c9dbaf8d6b --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 467.04761904761904 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c72b04f70ae633b95dc219dfb6123bce85b67a10 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cc5185f8d0225e44cef87eecd7c39d52415190c3 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,8 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.680538303557263 10.835016609257863 2.3492277757481728e-27 2.1000000049333786e-17 1.0500000024666893e-17 570 O43169,Q86YN1,O43657,P43307,Q9NS69,Q9H4I9,Q99595,P09601,Q9Y2R0,Q9BQE5,Q9NX00,O60830,O60725,Q9NZ45,Q8WY22,Q9H6V9,Q9UDW1,P00846,P57105,Q3SXM5,O95197,Q9H1E5,Q14849,Q9BSK2,P30519,P24390,Q9Y282,Q9C0H2,P24539,Q9P2W9,Q9BUR5,O00400,Q8NC54,Q6UW02,Q8NCH0,O14925,P51648,O75844,Q9UBX3,Q70HW3,Q15070,Q9H061,Q5T9L3,Q9NQC3,Q9Y584,Q8NBN3,O15127,O75964,Q96A26,Q96GC9,Q9Y619,O43676,Q86WC4,Q9H4I3,O43760,Q9Y487,Q7Z3D4,Q13505,Q9HC07,O00461,Q96PC5,Q5VW38,Q96EX1,Q15800,O43752,Q9NP80,O15173,O94919,Q14739,O95070,Q96KA5,Q9H6H4,O96005,Q8N0U8,Q8TCT9,Q15629,P05067,Q9BU23,Q9BUN8,Q5H8A4,Q6NUK4,Q8IZA0,Q96G23,Q86Y39,Q99720,Q9NZJ7,Q86UE4,Q9UG56,P12236,Q70UQ0,Q8N8Q8,Q9BV10,Q15392,Q96A57,Q9BT22,Q9Y6C9,P62942,Q8IV08,A1L0T0,Q96A33,Q9H3K2,Q9NX40,Q9H6K4,O95470,Q9HD45,P12235,Q9H330,P16435,Q96ES6,Q9HD20,Q08722,P27105,P67812,Q96I36,O60831,P13073,Q567V2,Q8WVC6,O95772,Q14534,P03886,Q07065,O43731,Q8N5M9,Q9NUQ2,P00387,P42892,Q12981,Q93050,Q9UBU6,Q96JJ7,Q8N511,Q8IXM6,Q99640,Q8TCT8,Q8WTV0,Q8NE01,Q9P035,Q9Y5M8,P51812,P38435,P04844,Q9HBM0,O94822,Q8NCG7,Q8NHH9,Q9BTX1,Q10472,Q16799,Q8N4V1,Q9UJ14,Q8TB61,Q13423,O15118,Q14728,Q16850,Q96CP7,Q9HC21,P11279,Q96RQ1,Q96N66,Q14108,Q96E52,Q9UIQ6,Q7KZN9,Q06136,Q969V3,Q9P0J0,P11117,Q9BXK5,P57088,O75438,O00264,Q96SK2,Q9NR28,Q03518,P56378,Q99808,O75381,Q13190,Q6ZXV5,Q9Y5U9,Q53GQ0,O76024,O75071,P51571,Q00765,Q9UKU0,Q96AG4,P16615,O75192,O15155,Q6NUQ4,O95249,Q86XL3,Q9H3N1,Q9UDX5,Q92542,P46977,Q96KC8,Q9BXS4,Q8TBA6,Q13277,Q7L0J3,Q6UW68,Q8TDW0,Q9BW72,O15258,Q9Y6N1,P05141,Q6P4A7,Q8WUK0,Q9BUB7,Q9H2C2,P27824,P35613,O75880,Q92804,Q9UBV2,Q8NF37,O43808,Q9H0U3,Q9GZY8,Q99805,Q8NCC3,P17152,Q8TBQ9,Q5VV42,Q9Y262,Q9UEU0,O15269,O94901,Q8N1F7,Q9P246,O15400,O15260,P56962,Q9UH62,Q07820,O14653,Q9NX62,Q8N2F6,Q9NTJ5,Q9NRB3,P37268,O75306,Q9NPL8,Q6NUM9,O95202,O95168,O75027,P05023,Q6ZRP7,Q5SNT2,Q99442,Q9Y5Y5,Q9HBU6,Q86Y82,P98194,Q9UGP8,Q99735,P49755,Q7Z2K6,Q92575,Q8NBX0,O75396,P18031,O43909,P50402,Q00325,Q5JRA6,Q9HCU5,Q9NPA0,Q9BTW9,Q9NZ01,Q9NXE4,P31350,P60228,Q9NPR9,P51572,O95674,P04439,Q9Y3B3,P15291,Q15005,P50416,Q3ZCQ8,P35610,P56192,Q15363,O14548,O95864,Q15041,Q9Y3A6,Q92896,Q96TC7,P10321,Q92643,P56134,Q12907,Q8IYS2,Q96S52,Q96S66,Q9Y320,Q9Y639,Q9H2V7,Q3B7T1,P55011,O43464,Q9BVC6,Q15904 311 +Transporters 0.5181267651326203 3.5196456155330824 0.0004321237569366 0.009035492508479 0.0022686497239176 372 P98194,Q9UGP8,Q9H4I9,P49755,Q8WY22,Q9H2D1,P57105,Q00325,Q5JRA6,Q9HCU5,Q9NPA0,Q14849,Q9BSK2,P24390,Q9C0H2,P51572,P45880,Q9BUR5,O00400,P04439,Q9Y3B3,Q9BW27,P21912,O75844,Q9UBX3,Q70HW3,Q15070,Q9H061,Q5T9L3,Q676U5,P50416,O43592,O15127,Q8NFH5,Q96GC9,Q15363,Q9Y619,Q86WC4,O94905,Q9UHB9,Q9HC07,Q96PC5,Q5VW38,Q9UJS0,Q12769,O43752,P04080,O95433,Q9NQZ5,Q96S66,Q9Y320,Q9Y639,Q9Y371,Q9H2V7,O96005,Q96P70,Q15629,P05067,Q15287,Q9BUN8,P55011,Q9BVC6,Q15904,Q99720,Q9NZJ7,P12236,Q8N8Q8,Q96A57,Q9Y6C9,P62942,Q96A33,P12235,Q9HD20,Q08722,P27105,O60831,O00560,P13073,Q07065,Q93050,Q9UBU6,Q96JJ7,Q8N511,Q8TCT8,Q8WTV0,Q8NE01,P04844,P40855,Q9HBM0,Q8NHH9,Q9BTX1,Q16799,O95373,Q8N4V1,Q8TB61,O15118,Q9HC21,P11279,P07602,Q96N66,O60784,Q14108,Q96E52,Q9C0E2,Q969V3,P57088,Q6NUK1,Q03518,Q99808,O75381,Q13190,Q6ZXV5,O76024,Q8NFH4,Q96AG4,P16615,O75192,Q9H3N1,P46977,Q8IYU8,Q96L92,Q9BXS4,Q16891,Q8TBA6,Q13277,P04083,Q6UW68,Q8TDW0,Q9BW72,O15258,P05141,Q6P4A7,Q9BUB7,Q9H2C2,Q07021,P35613,O15397,Q9UBV2,P61916,O43808,Q9H0U3,Q99805,Q92973,Q9UEU0,Q15006,O94901,Q9Y512,Q96HE7,Q8N1F7,Q9P246,P54105,P52292,O15260,P56962,O60313,Q7Z3B4,O00429,Q9BRK5,O96008,O95202,O75027,P05023,Q99442,Q9Y5Y5 164 +Predicted secreted proteins 0.4881321076209768 2.595772423244122 0.0094378552883225 0.180561685148913 0.0330324935091288 48 O75718,O00584,Q8N128,Q07021,P84157,Q02818,P61916,O60888,P80303,Q9BUR5,P43490,Q92520,Q9HB40,Q15165,Q9Y4P3,Q9NZ08,O94919,P04083,Q9UM22,P05067 20 +CD markers 0.5791603579340807 1.9531556243270145 0.0508011574980724 0.6654190585347688 0.1333530384324402 13 P11279,P54709,Q9UBG0,P35613,Q08722,P08183,P08195 7 +Metabolic proteins 0.2517814620006917 1.34192212531866 0.1796212470120701 0.9843576325056452 0.3143371822711228 866 Q86YN1,P98194,Q99735,P09601,O60725,Q99538,Q8NBX0,P46976,P18031,Q9UDW1,Q9H2D1,P00846,P49356,O43909,O60566,Q9UIJ7,P50897,Q00325,Q5JRA6,Q9BTY2,Q9P2J5,Q14849,Q9NZ01,Q9NXE4,P30519,Q9BTU6,Q8NCN5,O14949,P31350,Q9BRR6,P26885,P24539,P51572,O95674,Q9Y680,O00400,Q96PU5,Q13510,Q8NCH0,Q9BW27,P51648,P21912,O75844,Q9UBX3,Q70HW3,Q8NBQ5,P15291,Q15005,P48729,P50416,Q96KB5,P35610,P0DP25,P04066,Q15165,O00754,O75964,P56192,Q8NFH5,Q9NPH0,Q9Y619,O43676,P10644,P10619,O95864,P21964,Q10471,Q9Y487,Q9UMR5,Q7LGA3,Q92643,P56134,O14965,Q9UJS0,Q9UBS8,Q99956,Q8NEB9,P78417,Q12769,Q15800,P49427,O60762,Q9NP80,Q06520,Q9NQZ5,Q14739,Q5H8A4,Q96G23,Q86SQ9,Q86Y39,Q9H773,P23786,Q9UHG3,Q9UG56,P12236,Q13126,Q9BV10,Q15392,Q8NBN7,Q9BT22,P62942,Q8IV08,O95470,P17900,P12235,P16435,P04062,P67812,P13073,O14579,P15586,Q14534,O43924,P03886,P07099,P09960,Q9NUQ2,P00387,Q93050,Q96JJ7,P00374,Q99640,O43708,Q8WTV0,Q9P035,P51812,P04844,Q9BWD1,Q8NCG7,Q9BTX1,Q10472,Q05655,Q969T7,P06865,Q9UJ14,Q8TB61,Q16836,Q13423,O15118,Q16850,Q9HC21,Q9UBP6,P07602,O96000,Q96N66,Q10713,O95302,Q06136,O14773,P08236,Q9P0J0,P11117,O15254,P06280,Q9BQG2,P16278,P52789,P55201,O75438,P07237,P56378,Q99808,Q9NWM8,Q5T2R2,Q53GQ0,P51571,Q8NFH4,Q9UKU0,Q9NVH6,P16615,O75192,P56385,P46977,Q8N4Q0,Q9HA64,Q13395,Q9HBH5,P55786,Q8IVS2,Q9BW72,P54802,O43505,Q96L58,P05141,Q8WUK0,P14324,P10253,Q8NF37,O43808,Q92820,Q8NCC3,Q53H12,P53701,O15269,Q8N1F7,P13674,P43490,Q8IXJ6,Q96K76,Q7Z3B4,Q9NX62,Q15067,P16930,O00429,Q9NTJ5,Q9NRB3,P37268,O75306,O95168,P05023,Q15418,Q9HBU6 212 +FDA approved drug targets 0.2831793365892258 0.4560778938174509 0.6483339660184182 0.9999999997057348 0.8509383303991739 114 Q16850,Q99720,P05141,P23786,P12236,P14324,P49356,P62942,P49721,P12235,Q14534,P03886,P16615,P21964,P00374,P38435,Q7L0J3,Q05655,P04083,Q8N0U8,Q16836,Q13423,P05067 23 +Candidate cardiovascular disease genes 0.3656755804439673 0.2141671553098426 0.83041670809306 1.0 1.0 7 Q15165 1 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..70d2aebc5c7afc10eaba471f75a95fac8b3fbcfe --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG8", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANKFY1", "ANKHD1", "ANKLE2", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATG13", "ATG16L1", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BDH2", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRI3BP", "BRIX1", "BROX", "BRPF1", "BSDC1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf76", "C11orf58", "C12orf43", "C12orf73", "C14orf2", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C20orf24", "C2CD2", "C2orf49", "C5orf15", "C5orf24", "C8orf33", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCDC88A", "CCDC93", "CCDC94", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPK", "CENPU", "CENPV", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COIL", "COLEC12", "COLGALT1", "COMMD2", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2L", "CPD", "CPE", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP2", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP2", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERCC2", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM162A", "FAM177A1", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FOXRED2", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH8", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD2A", "HIKESHI", "HINT3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1211", "KIAA2013", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFAP3", "KIFBP", "KIFC1", "KLC1", "KLC2", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3HYPDH", "LAMB1", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD1L1", "MAGED2", "MAGT1", "MAK16", "MAN1A2", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAPK1", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCH5", "MARCKS", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBIP", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED24", "MED25", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL14", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MIB1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL3", "MRPL37", "MRPL39", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS14", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MXRA7", "MYBBP1A", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NACC1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F2", "NRBP1", "NRDC", "NRM", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OSTM1", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11A", "PEX14", "PEX16", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PWP2", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG2", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC15A4", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A1AP", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG8", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D10A", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TCP11L1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLCD1", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM33", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMLHE", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSR1", "TSR2", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3C", "UBE4A", "UBE4B", "UBLCP1", "UBQLN2", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WASHC3", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WLS", "WNK1", "WRAP53", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF207", "ZNF24", "ZNF281", "ZNF326", "ZNF593", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ACAT2", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL6", "ADPGK", "AGK", "AGPAT5", "AHSA1", "AK3", "ALDH3A2", "ALG1", "ALG12", "ANKLE2", "ANXA1", "APOL2", "APOO", "APP", "ARL6IP1", "ARMC10", "ARMCX3", "ARV1", "ASAH1", "ATG16L1", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BCAP31", "BCL2L13", "BET1", "BNIP1", "BRI3BP", "BRPF1", "BSG", "BUB1B", "C14orf2", "C1QBP", "C5orf15", "CALM3", "CANX", "CCDC47", "CD47", "CDC34", "CDKAL1", "CDS2", "CERS2", "CHST12", "CHST14", "CISD1", "CKAP4", "CLCC1", "CLNS1A", "CLPTM1", "CLPTM1L", "CNNM3", "COA3", "COMT", "COPE", "COX11", "COX14", "COX15", "COX18", "COX4I1", "COX7A2L", "CPT1A", "CPT2", "CRTAP", "CSNK1A1", "CSTB", "CTSA", "CUTA", "CYB5B", "CYB5R3", "CYP20A1", "CYP51A1", "DAGLB", "DCAKD", "DCTPP1", "DERL1", "DHCR24", "DHDDS", "DHFR", "DIABLO", "DNAJC1", "DNM1L", "DOLPP1", "DPM1", "DUSP9", "ECE1", "EDRF1", "EFCAB14", "EIF3E", "EIF3L", "EMC2", "EMC7", "EMD", "ENDOD1", "EPDR1", "EPHX1", "ERAP1", "ERGIC2", "ERGIC3", "ERLIN2", "ERMP1", "ERO1A", "ETNK1", "EXTL3", "FADS2", "FAH", "FAM162A", "FAM177A1", "FAM3C", "FAM8A1", "FDFT1", "FDPS", "FKBP14", "FKBP1A", "FKBP2", "FKBP7", "FKBP9", "FN3KRP", "FNTB", "FUCA1", "FUCA2", "GAA", "GALNT1", "GALNT2", "GBA", "GGCX", "GGH", "GGT7", "GHITM", "GLA", "GLB1", "GLG1", "GM2A", "GNS", "GOLGA5", "GOLIM4", "GOSR1", "GOSR2", "GPR107", "GPR108", "GSTO1", "GSTZ1", "GUSB", "GYG1", "HACD3", "HADH", "HCCS", "HEXA", "HIGD2A", "HK2", "HLA-A", "HLA-C", "HM13", "HMOX1", "HMOX2", "HS2ST1", "HSD17B11", "HSD17B12", "HSDL1", "HTRA2", "ICMT", "IER3IP1", "IKBIP", "ILVBL", "IMMT", "IMPAD1", "IPO7", "IPO8", "IPO9", "JAGN1", "KDELR1", "KDELR3", "KDSR", "KIAA0319L", "KIAA2013", "KPNA2", "LAMP1", "LARS", "LBR", "LDAH", "LETM1", "LGMN", "LMAN2", "LMF2", "LNPEP", "LPCAT1", "LRRC59", "LRRC8C", "LTA4H", "LTN1", "LYSMD3", "MAGT1", "MAN2B1", "MARS", "MBOAT7", "MCAT", "MCL1", "METTL1", "MFF", "MFSD10", "MFSD3", "MGST2", "MIA2", "MIA3", "MICU2", "MMGT1", "MPV17L2", "MRC2", "MSMO1", "MTAP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTX1", "MXRA7", "NAGLU", "NAMPT", "NCLN", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFS2", "NEDD4L", "NNT", "NPC1", "NPC2", "NPEPPS", "NPTN", "NRM", "NT5C3B", "NUCB1", "NUCB2", "NUDT12", "NUP160", "NUP35", "NUP37", "NUP54", "NUP85", "NUP93", "OCIAD1", "OMA1", "OPA1", "OPA3", "OSTM1", "OXA1L", "P4HA1", "P4HB", "PBK", "PCYOX1", "PDE6D", "PDPR", "PDSS1", "PEX11A", "PEX14", "PEX16", "PEX19", "PGRMC1", "PGRMC2", "PI4K2A", "PIGG", "PIGK", "PIGS", "PIK3C3", "PISD", "PKMYT1", "PLA2G15", "PLD3", "PMPCA", "PNPLA8", "PON2", "POR", "PPT1", "PPT2", "PRAF2", "PREB", "PRKAR1A", "PRKCD", "PSAP", "PSMB2", "PTPMT1", "PTPN1", "QSOX2", "RDH13", "RDH14", "REEP3", "REEP4", "REEP5", "RER1", "RETSAT", "RMDN3", "RNASET2", "RNF14", "RNPS1", "RPN2", "RPS6KA1", "RPS6KA3", "RRM2", "RTN1", "RTN3", "RTN4", "SACM1L", "SAMM50", "SCAMP2", "SCARB1", "SCARB2", 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0000000000000000000000000000000000000000..8173bbfc2474a19a21d3bbf26a6900d4896e0fd4 --- /dev/null +++ b/protein_atlas_subcellular_location_all/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9035acf9765e25554f5773173919b30f9a7ce0c052fcf3f3582f876900841718 +size 82246 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..69f441970cb02663d549808e83f8e8e96779b26e --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Golgi apparatus 69 178 2.7959509687105304 0.0051747250426006 46.45873786407767 176.03155339805826 1.3643789213018729 0.3972771337532677 14.511319530749702 26.453870355965975 1.6568954592349954 0.4161874156663988 0.0005680904240317 0.2072178934080302 0.0234679865121522 0.0005897523082677 0.0010223831843269 +Endoplasmic reticulum 81 205 2.6506397417715566 0.0080339484791933 55.37621359223301 196.57766990291265 1.2201083743235763 0.4903523338807414 18.868778270733547 13.264167600850914 1.8573715045605257 0.4308007257692164 4.92418824517836e-20 0.0253940315541129 0.000503366064418 3.621274769199311e-15 3.0698544226175863e-20 +Nuclear membrane 30 65 2.247692392220597 0.0245958114581099 16.817961165048544 62.713592233009706 0.5402747034161678 0.5293388535672136 7.339768502370818 5.865441797870943 1.2287110387783358 0.3803813474041967 0.0208347784661806 0.2177059049323894 0.5250511846313772 0.0329605406234942 0.0158574899039515 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..656f9caf7e278dc63877e5c0f394e51c0608b72c --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3040, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 142.78787878787878 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3cc53d46e4709874cc698861e825f5e269ce7abf --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C293/C293_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e91a62e9c453f300c4b2b0d5547f4f7991d4bfdb --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,10 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Golgi apparatus 0.4835887236545331 2.7959509687105304 0.0051747250426006 0.1573548021542549 0.0345738875576109 178 Q86Y82,O75122,O15258,P98194,Q8IZA0,P49755,P09601,Q96RQ1,Q6NUQ1,Q9UG56,O95302,Q9NUJ3,Q02818,P50897,P40616,A1L0T0,P80303,P24390,P16278,Q9HD45,Q9NPR9,Q6ZU35,O00231,Q9UEU0,P04439,Q8NC54,P67812,Q8NCH0,P15291,O14579,Q9NWM8,Q13190,O15260,Q9UH62,Q8NBN3,Q92520,Q9HB40,O75071,O14653,O15127,Q9NX62,Q93050,Q9UBU6,Q6NUQ4,Q9NTJ5,Q10471,O43760,Q9H4A6,Q99640,Q92896,Q9NRB3,Q9HC07,O00461,Q5VW38,Q8IYS2,Q9NW68,Q9BRK5,Q8TBA6,O43752,Q8N4Q0,Q9NP80,Q6ZRP7,Q05655,O95070,Q96SU4,Q9H2V7,Q8TDW0,Q9H0U4,P05067 69 +Endoplasmic reticulum 0.4799472033088864 2.6506397417715566 0.0080339484791933 0.2337072635837057 0.0345738875576109 205 O43169,P43307,Q9UGP8,Q99735,Q92575,P18031,P50402,P84157,Q9HCU5,O95197,Q9NZ01,Q14849,P51572,Q9P2W9,O95674,Q9Y680,P51648,Q5T9L3,Q9NQC3,P35610,Q96GC9,O94905,P21964,Q15041,P67809,Q96PC5,Q99956,Q15800,Q96KA5,Q9H6H4,O96005,Q8N0U8,Q8TCT9,Q9BUN8,Q96G23,Q86UE4,Q70UQ0,Q9BV10,Q96A57,Q9BT22,Q8IV08,Q96A33,Q14257,O95470,O60831,O43731,P00387,Q12981,Q9P035,P04844,Q8NHH9,Q16799,Q05655,Q16850,Q9NR31,O00264,P07237,Q92791,Q03518,Q9Y5U9,P51571,Q00765,Q96AG4,Q6NUQ4,Q86XL3,Q9H3N1,O43852,Q96HY6,Q96KC8,Q6UW68,Q13409,P27824,Q8NF37,O15269,P13674,O15260,P37268,Q96CN7,Q99442,Q9H3G5,Q9H0U4 81 +Nuclear membrane 0.4265395741971522 2.247692392220597 0.0245958114581099 0.56036492478905 0.0737874343743298 65 Q14728,Q9BVC6,Q96G23,P57740,Q9H8M7,P50402,Q9NRG9,Q9H1E5,Q9NXE4,O14735,O60783,O75976,Q96SK2,O94901,P67812,O00560,O15260,Q96PE3,Q8NFH5,Q8IXM6,Q96SY0,Q8IY37,P56134,O95168,Q9BTX1,Q13277,O94919,Q14739,Q5SNT2,Q6UW68 30 +Centriolar satellite 0.4335985901407396 1.5381887251168245 0.1240024769602701 0.9873352978805922 0.2922915528349224 26 O43169,Q15907,O60784,P41208 4 +Mitochondria 0.385729714070613 1.4111133591153435 0.1582111915324402 0.9965982384460936 0.3480646213713685 387 Q9NS69,Q8N4H5,Q9H4I9,Q99595,Q9H2W6,Q9Y2R0,O60830,Q9NZ45,Q8WY22,Q9H2D1,P57105,Q3SXM5,Q9UIJ7,Q00325,Q96B49,Q8NCN5,O14949,P24539,P62072,P45880,Q5T9A4,O60783,O43615,Q9BUR5,P21912,O14925,Q9NVT9,Q9UBX3,Q70HW3,Q15070,Q9NVI7,Q99797,P50416,Q8TC07,Q7Z7H8,O75964,Q96A26,Q9H4I3,Q7LGA3,Q13505,Q96CU9,Q96EX1,Q69YU5,Q9Y277,Q9NQZ5,Q5XKP0,Q86Y39,P23786,P12236,Q8NBN7,Q9Y6C9,Q9NUL7,Q9H3K2,Q9NX40,P12235,Q96I36,P13073,P28070,Q9NUQ2,P00374,Q5JRX3,Q16836,Q13423,Q6DKK2,Q9HC21,O60220,Q96E52,Q10713,Q7KZN9,O95302,Q9P0J0,P52789,Q9BXK5,O75438,Q9NUJ1,Q6NUK1,Q9NR28,P56378,Q9NQE9,Q9NVH6,O15091,P56385,Q9UDX5,Q8IYU8,Q16891,P82933,Q8IVS2,Q9BW72,Q96BR5,Q9Y394,P05141,Q6P4A7,Q8WUK0,Q9BUB7,Q07021,P51530,Q9GZY8,Q53H12,P53701,P17152,Q9Y512,P13674,Q07820,O60313,Q8N2F6,O75306,Q9NPL8,Q16740,O96008,O95202,O95168,O75027,Q9NX63 113 +Intermediate filaments 0.37881443967328 1.1948879378966828 0.232130816211594 0.9998361377628298 0.4629828044319589 33 Q86YN1,Q16352,P08670,Q96K76,Q99442,Q3SXM5 6 +Peroxisomes 0.4324357917222299 1.0250086087351882 0.3053591256918944 0.9999940008317372 0.5038425573916258 14 O75381,O15254,P40855,Q15067,P28288,O43808 6 +Vesicles 0.3323857598046597 0.2553390964892729 0.7984612058210296 1.0 0.9085937859342752 299 Q86YN1,Q15907,O60506,P07602,Q96RQ1,Q8N128,Q6P4A7,Q9H2C2,P35613,P10253,O95302,Q3SXM5,Q9BPZ3,P50897,P08236,A1L0T0,Q14849,Q08AM6,O75153,P30519,Q8WZA9,P24390,P16278,P52789,Q9HD45,P17900,Q8NCC3,Q53H12,Q8TBQ9,P16435,Q96ES6,Q9HD20,Q08722,O00400,Q9UEU0,P27105,Q96SK2,O60831,Q92791,Q92564,P13674,Q5T2E6,O95772,Q14534,Q8N5M9,Q96K76,Q9NUD5,O15127,Q93050,Q86WC4,P10619,O00429,Q8IXH7,P21964,Q9Y487,Q9UMR5,Q8TCT8,Q9NRY5,Q8WTV0,Q9NRV9,Q96L92,Q9NR50,Q8N4Q0,Q13277,O95070,Q96SU4,P06865,Q9UJ14,Q8TB61,P05067,O15118 71 +Lysosomes 0.2887014771669377 0.0879669365550636 0.9299029550450668 1.0 1.0 13 P51149,P02786,O60749,Q8WTV0,Q8IY95,O15400 6 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c2a20cbbf75e0438657a205df242193d53446b28 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD14B", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ADA", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG8", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARID1A", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC5", "ARV1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATG13", "ATG16L1", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B4GALT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRI3BP", "BRIX1", "BROX", "BRPF1", "BSDC1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf76", "C11orf58", "C12orf43", "C12orf73", "C14orf2", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C20orf24", "C2CD2", "C2orf49", "C5orf15", "C5orf24", "C8orf33", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCDC93", "CCDC94", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPU", "CENPV", "CEP170", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT10", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COIL", "COLEC12", "COLGALT1", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ5", "COQ8A", "CORO1B", "COTL1", "COX14", "COX15", "COX4I1", "COX5B", "COX7A2L", "CPD", "CPE", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF2", "CSTF3", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DFFA", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELP1", "ELP2", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERCC2", "ERCC6L", "ERGIC2", "ERH", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM162A", "FAM177A1", "FAM208A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGT7", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GORASP2", "GOSR2", "GOT1", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM3", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP4", "GTPBP8", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HEXA", "HGH1", "HGS", "HIBCH", "HIF1AN", "HIGD2A", "HIKESHI", "HINT3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTRA2", "HTT", "HUWE1", "IAH1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "ISCU", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1211", "KIAA2013", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFAP3", "KIFC1", "KLC1", "KLC2", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3HYPDH", "LAMC1", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPCAT1", "LPCAT2", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM7", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "MACF1", "MAD1L1", "MAGED2", "MAK16", "MAN1A2", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAPK1", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCH5", "MARCKS", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBIP", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED25", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL14", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MIB1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL37", "MRPL39", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS14", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MXRA7", "MYBBP1A", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NACC1", "NAE1", "NAF1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NELFCD", "NELFE", "NEMF", "NES", "NF1", "NFKBIE", "NFS1", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F2", "NRBP1", "NRDC", "NRM", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OSTM1", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PUM3", "PWP2", "PXN", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB11B", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCL1", "RCN1", "RCN2", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "REPS1", "RER1", "RETREG2", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF14", "RNF20", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPUSD2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIN3A", "SIN3B", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A1AP", "SLFN11", "SLIRP", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG8", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPEN", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRCAP", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D10A", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP11L1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM11", "TMEM126A", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM70", "TMEM87A", "TMEM97", "TMLHE", "TMOD3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSR1", "TSR2", "TSTA3", "TTC1", "TTC19", "TTC37", "TTC38", "TTC4", "TTLL12", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TXLNA", "TXLNG", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3C", "UBE4A", "UBLCP1", "UBQLN2", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC2", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WASHC3", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR74", "WDR77", "WDR82", "WIPI2", "WIZ", "WLS", "WNK1", "WRAP53", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFR", "ZMYM2", "ZMYM4", "ZNF207", "ZNF24", "ZNF281", "ZNF326", "ZNF593", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAAS", "ABCB7", "ABCD3", "ABHD10", "ACOX1", "ACOX3", "AGK", "AGPAT5", "AK3", "ALDH3A2", "ALG1", "ALG12", "ANKLE2", "APOO", "APP", "ARL1", "ARL6IP1", "ARMC1", "ARMC10", "ARMCX3", "ARV1", "ATAD3A", "ATAD3B", "ATL2", "ATP13A1", "ATP2C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "B4GALT1", "BCAP31", "BCL2L13", "BNIP1", "BRI3BP", "BSDC1", "BSG", "C10orf76", "C12orf73", "C14orf2", "C19orf70", "C1QBP", "C5orf15", "CALU", "CANX", "CCDC47", "CD47", "CDIPT", "CDS2", "CERS2", "CETN2", "CHCHD3", "CHST12", "CHST14", "CISD1", "CLASP2", "CLPP", "CLPTM1", "CLPTM1L", "CLUH", "COA3", "COA7", "COMT", "COPE", "COX14", "COX15", "COX4I1", "CPD", "CPT1A", "CPT2", "CPVL", "CTSA", "CYB5B", "CYB5R3", "CYP51A1", "DCUN1D4", "DDRGK1", "DDX28", "DERL1", "DHFR", "DHRS7", "DHX37", "DIABLO", "DNA2", "DNAJC1", "DNM1L", "DOLPP1", "DUSP9", "DYNC1I2", "EFCAB14", "EIF2B3", "EMD", "ENDOD1", "ERGIC2", "ERLIN2", "FAM114A2", "FAM162A", "FAM177A1", "FAM3C", "FAM8A1", "FDFT1", "FKBP14", "FKBP7", "FKBP9", "FOXRED1", "GAA", "GALNT2", "GGT7", "GHITM", "GLB1", "GLG1", "GM2A", "GOLGA5", "GOLIM4", "GOLPH3", "GOSR2", "GPR107", "GPR108", "GUSB", "HACD3", "HADH", "HCCS", "HEBP1", "HEXA", "HIGD2A", "HINT3", "HK2", "HLA-A", "HM13", "HMOX1", "HMOX2", "HS2ST1", "HSDL1", "IER3IP1", "IKBIP", "ILVBL", "IMMT", "IMPAD1", "INA", "INPP4A", "INTS14", "IRGQ", "ISOC1", "JAGN1", "KDELR1", "KDELR3", "KIAA0319L", "KIAA0391", "KIAA1211", "KIAA2013", "LBR", "LETM1", "LPCAT1", "LRRC59", "LRRC8C", "MCAT", "MCL1", "MFF", "MFSD10", "MFSD3", "MGST2", "MIA2", "MICU2", "MINDY3", "MIPEP", "MRPL10", "MRPL46", "MRPS14", "MRPS9", "MSMO1", "MTCH2", "MTDH", "MTFP1", "MTX1", "MXRA7", "NDC1", "NDUFA11", "NDUFA13", "NDUFB1", "NDUFB4", "NDUFS2", "NELFCD", "NNT", "NPC1", "NRM", "NUCB1", "NUCB2", "NUP107", "NUP35", "OCIAD1", "OMA1", "OPA1", "OSBPL9", "OSTM1", "OXA1L", "P3H4", "P4HA1", "P4HB", "PAIP2", "PDPR", "PEX14", "PEX19", "PGRMC1", "PISD", "PITRM1", "PKMYT1", "PLA2G15", "PLD3", "PMPCA", "PNPLA8", "POR", "PPT1", "PPT2", "PRAF2", "PREB", "PRKCD", "PSAP", "PSMB4", "PSMD11", "PTPMT1", "PTPN1", "QSOX2", "RAB11B", "RAB1B", "RAB7A", "RCN2", "RDH13", "REEP4", "REEP5", "RER1", "RINT1", "RPN2", "RTN1", "RTN3", "RTN4", "SACM1L", "SAMM50", "SAR1A", "SCAMP2", "SCARB1", "SCPEP1", "SDCBP", "SDF4", "SDHB", "SEC11A", "SEC62", "SEC63", "SFXN4", "SGPL1", "SLC25A10", "SLC25A17", "SLC25A19", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC33A1", "SLC35B2", "SMDT1", "SMIM12", "SMPD4", "SNX2", "SNX27", "SOAT1", "SPNS1", "SPPL2A", "SPTLC1", "SQLE", "SSR1", "SSR4", "STARD3", "STARD3NL", "STARD7", "STOM", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "SUN1", "SURF4", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAP1", "TBC1D15", "TCP11L1", "TECR", "TFRC", "TIMM10", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM8A", "TIMMDC1", "TM9SF3", "TMED10", "TMEM109", "TMEM11", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM70", "TMEM87A", "TMLHE", "TMX1", "TMX4", "TOM1", "TOMM22", "TOMM40", "TOMM5", "TOMM6", "TRABD", "TTC19", "UBXN4", "UQCRQ", "USP47", "VAC14", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VMP1", "VTI1B", "WLS", "YBX1", "YIF1A", "ZADH2", "ZCCHC3"]} \ No newline at end of file