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  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/consensus.joblib +3 -0
  4. interpro_active_site/df_merge.tsv +1 -0
  5. interpro_active_site/metrics.json +7 -0
  6. interpro_active_site/paths.json +1 -0
  7. interpro_active_site/result.tsv +5 -0
  8. interpro_active_site/selections.json +1 -0
  9. interpro_binding_site/advanced/idx2term.json +1 -0
  10. interpro_binding_site/basic/idx2term.json +1 -0
  11. interpro_binding_site/consensus.joblib +3 -0
  12. interpro_binding_site/df_merge.tsv +1 -0
  13. interpro_binding_site/metrics.json +7 -0
  14. interpro_binding_site/paths.json +1 -0
  15. interpro_binding_site/result.tsv +7 -0
  16. interpro_binding_site/selections.json +1 -0
  17. interpro_conserved_site/advanced/idx2term.json +1 -0
  18. interpro_conserved_site/advanced/plot_0.png +3 -0
  19. interpro_conserved_site/basic/idx2term.json +1 -0
  20. interpro_conserved_site/basic/plot_0.png +3 -0
  21. interpro_conserved_site/basic/plot_1.png +3 -0
  22. interpro_conserved_site/basic/plot_2.png +3 -0
  23. interpro_conserved_site/consensus.joblib +3 -0
  24. interpro_conserved_site/df_merge.tsv +3 -0
  25. interpro_conserved_site/metrics.json +7 -0
  26. interpro_conserved_site/paths.json +1 -0
  27. interpro_conserved_site/result.tsv +30 -0
  28. interpro_conserved_site/selections.json +1 -0
  29. interpro_domain/advanced/idx2term.json +1 -0
  30. interpro_domain/basic/idx2term.json +1 -0
  31. interpro_domain/basic/plot_0.png +3 -0
  32. interpro_domain/basic/plot_1.png +3 -0
  33. interpro_domain/basic/plot_10.png +3 -0
  34. interpro_domain/basic/plot_2.png +3 -0
  35. interpro_domain/basic/plot_3.png +3 -0
  36. interpro_domain/basic/plot_4.png +3 -0
  37. interpro_domain/basic/plot_5.png +3 -0
  38. interpro_domain/basic/plot_6.png +3 -0
  39. interpro_domain/basic/plot_7.png +3 -0
  40. interpro_domain/basic/plot_8.png +3 -0
  41. interpro_domain/basic/plot_9.png +3 -0
  42. interpro_domain/consensus.joblib +3 -0
  43. interpro_domain/df_merge.tsv +7 -0
  44. interpro_domain/metrics.json +7 -0
  45. interpro_domain/paths.json +1 -0
  46. interpro_domain/result.tsv +241 -0
  47. interpro_domain/selections.json +0 -0
  48. interpro_family/advanced/idx2term.json +1 -0
  49. interpro_family/basic/idx2term.json +1 -0
  50. interpro_family/basic/plot_0.png +3 -0
interpro_active_site/advanced/idx2term.json ADDED
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+ {}
interpro_active_site/basic/idx2term.json ADDED
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+ {}
interpro_active_site/consensus.joblib ADDED
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+ size 67920
interpro_active_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3039,
4
+ "annotations_size": 55,
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+ "title": "Average number of proteins per term",
6
+ "value": 2.6
7
+ }
interpro_active_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C295/C295_val_log2fc"}
interpro_active_site/result.tsv ADDED
@@ -0,0 +1,5 @@
 
 
 
 
 
 
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ L-lactate dehydrogenase, active site [IPR018177] 0.7290088903523082 0.4958193518576239 0.6200218701841052 1.0 0.9428330948240298 2 P00338 1
3
+ Ubiquitin-conjugating enzyme, active site [IPR023313] 0.4239330757761484 0.4286093543605366 0.6682075368448879 1.0 0.9428330948240298 8 P49427,P60604 2
4
+ Peptidase S9, serine active site [IPR002471] 0.5620678300954796 0.1377756587644582 0.8904177223649641 1.0 0.976650538260052 2 P48147 1
5
+ Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999] 0.2875260902394246 0.0262397318201573 0.9790661253728457 1.0 0.9971969795464168 3 Q16881 1
interpro_active_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
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+ {"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MDH1", "MDH2", "MTMR2", "NEK9", "NME1", "NME2", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE2T", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["CDC34", "LDHA", "PREP", "TXNRD1", "UBE2G2"]}
interpro_binding_site/advanced/idx2term.json ADDED
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interpro_binding_site/basic/idx2term.json ADDED
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interpro_binding_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
interpro_binding_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3039,
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+ "annotations_size": 31,
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+ "title": "Average number of proteins per term",
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+ "value": 4.548387096774194
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interpro_binding_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C295/C295_val_log2fc"}
interpro_binding_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Biotin-binding site [IPR001882] 0.8174629324546945 1.8769106948975476 0.0605303348092129 0.8556670096302756 0.6352528309721244 4 P05165,Q13085,Q96RQ3 3
3
+ Peptidase M16, zinc-binding site [IPR001431] 0.6984324023444336 1.5424999057127795 0.1229521608333144 0.9828714038523396 0.6352528309721244 5 P22695,O43847,Q10713 3
4
+ Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.7728021073427693 0.6264166841752917 0.5310416690202553 0.99999999993615 1.0 2 O75600 1
5
+ Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798] 0.6924596641422461 0.3964059755594103 0.6918055585363567 1.0 1.0 2 P34897 1
6
+ Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578] 0.4527494237734566 0.0461889939274576 0.963159614686987 1.0 1.0 2 Q9Y617 1
7
+ Aconitase family, 4Fe-4S cluster binding site [IPR018136] 0.4385907145209057 0.0408377573151789 0.967425238468664 1.0 1.0 2 P21399 1
interpro_binding_site/selections.json ADDED
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1
+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "ITSN2", "LETM1", "LPCAT2", "MACF1", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TKT", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["ACACA", "ACO1", "GCAT", "MCCC1", "NRDC", "PCCA", "PMPCA", "PSAT1", "SHMT2", "UQCRC2"]}
interpro_conserved_site/advanced/idx2term.json ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
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+ Guanylate kinase, conserved site [IPR020590] 2 5 2.367101130529488 0.0179280331974998 2.3980582524271843 5.25 0.6064346340666176 0.4240795168052628 1.6195996498310523 1.4740884957165508 0.9685287933135084 0.3034897017004088 0.0012601973854463 0.0001426699384292 0.0020770710993276 0.0141665154869097
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+ Proteasome beta-type subunit, conserved site [IPR016050] 5 8 2.241371975396087 0.025001990253151 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.0479914252810258 0.004071454093033 6.596771644487082e-05 2.312503759377148e-06
interpro_conserved_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3039,
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+ "annotations_size": 271,
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+ "title": "Average number of proteins per term",
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+ "value": 2.5830258302583027
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+ }
interpro_conserved_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C295/C295_val_log2fc"}
interpro_conserved_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.969456027789264 2.4783145236048187 0.0132004723300833 0.9727076565628072 0.7394779481534935 4 P48735 1
3
+ Guanylate kinase, conserved site [IPR020590] 0.8916814843950269 2.367101130529488 0.0179280331974998 0.9925725766873804 0.7394779481534935 5 Q14168,Q9NZW5 2
4
+ Proteasome beta-type subunit, conserved site [IPR016050] 0.822190821972227 2.241371975396087 0.025001990253151 0.998952845876042 0.7394779481534935 8 P49721,P49720,P28074,P28070,P20618 5
5
+ Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.5897919791643293 1.1892258463326777 0.2343508063438344 1.0 0.8776342832087478 7 P05091,O94788 2
6
+ Sterol reductase, conserved site [IPR018083] 0.9380968060586096 1.1856283095920377 0.2357691173171763 1.0 0.8776342832087478 2 Q14739 1
7
+ Ubiquitin specific protease, conserved site [IPR018200] 0.5817631831428732 1.1113205873237773 0.2664303808933015 1.0 0.9102326036243495 9 O94966,Q14694,Q86UV5 3
8
+ Haem oxygenase conserved site [IPR018207] 0.8192295027988056 0.7753632037068424 0.4381250717306728 1.0 0.989432453658436 2 P30519 1
9
+ Tetraspanin, conserved site [IPR018503] 0.800131708923267 0.7129959346541759 0.4758482727691828 1.0 0.9966748085130196 2 O43657 1
10
+ RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719] 0.7454725057622591 0.5435948128526132 0.5867203300652253 1.0 0.9966748085130196 2 O00442 1
11
+ RNA polymerase, beta subunit, conserved site [IPR007121] 0.7352650642081013 0.5137718484427041 0.6074115122781276 1.0 0.9966748085130196 2 P30876 1
12
+ Macrophage migration inhibitory factor, conserved site [IPR019829] 0.6960816595324286 0.4058122157288537 0.6848805823209971 1.0 0.9966748085130196 2 P30046 1
13
+ Zinc finger, RING-type, conserved site [IPR017907] 0.421607810248692 0.3882404034487408 0.697838135924091 1.0 0.9966748085130196 10 P19474 1
14
+ 3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.6842278564372745 0.3754190787975383 0.707348817981625 1.0 0.9966748085130196 2 Q16836 1
15
+ Ubiquitin interacting motif [IPR003903] 0.4144975288303065 0.2832647597764949 0.7769738890446323 1.0 0.9966748085130196 4 P55036,Q92783,O14964 3
16
+ Profilin conserved site [IPR027310] 0.6437273625287998 0.2806486610347192 0.7789798892056317 1.0 0.9966748085130196 2 P07737 1
17
+ Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 0.3757399709390349 0.2709960985097529 0.7863940329641195 1.0 0.9966748085130196 7 P05091,O94788 2
18
+ S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082] 0.635166282515638 0.2625437593889516 0.7929022530533658 1.0 0.9966748085130196 2 O43865 1
19
+ Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.3679208876004745 0.2597745578279785 0.7950376772845618 1.0 0.9966748085130196 6 P42356 1
20
+ DNA topoisomerase, type IIA, conserved site [IPR018522] 0.6180441224892931 0.2284753700344731 0.8192767016491114 1.0 0.9966748085130196 2 Q02880 1
21
+ Actin, conserved site [IPR004001] 0.6147513994073042 0.2222573801224332 0.8241135280624969 1.0 0.9966748085130196 2 O96019 1
22
+ Acyl-CoA-binding protein, ACBP, conserved site [IPR022408] 0.6131050378663094 0.2191892287545701 0.826502645693185 1.0 0.9966748085130196 2 O75521 1
23
+ F-actin capping protein, alpha subunit, conserved site [IPR017865] 0.5765558116562314 0.1581803675749627 0.8743146733896388 1.0 0.9966748085130196 2 P47755 1
24
+ DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.3541173039779238 0.1319621291078739 0.8950142463201631 1.0 0.9966748085130196 14 Q08211,P54132,O43143,P18074,Q8IX18,Q8TDI0,O60231,Q14562,Q92620 9
25
+ Dynamin, GTPase region, conserved site [IPR019762] 0.5446163977609377 0.116002228570035 0.9076507755779322 1.0 0.9966748085130196 2 O00429 1
26
+ Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.3880105401844508 0.1122323810933799 0.91063915495709 1.0 0.9966748085130196 3 Q96CW1,Q9Y2T2 2
27
+ Ribosomal protein L3, conserved site [IPR019926] 0.5284820546591916 0.0985190004951796 0.921520185138844 1.0 0.9966748085130196 2 P09001 1
28
+ Aldo/keto reductase, conserved site [IPR018170] 0.4748106684227706 0.0569564650330452 0.95457987468115 1.0 0.99908919674929 2 P14550 1
29
+ GTP1/OBG, conserved site [IPR006074] 0.4685544945669995 0.0535767500692031 0.9572723806573862 1.0 0.99908919674929 2 P55039 1
30
+ ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629] 0.2924083415005926 0.0051487919689941 0.9958918765322607 1.0 1.0 19 Q92841,Q13206,Q9H0S4,Q9NVP1,Q9Y6V7,Q8N8A6,Q8TDD1,O00571,P17844,Q9GZR7 10
interpro_conserved_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycerate/sugar phosphate transporter, conserved site [IPR021159]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "PTR2 family proton/oligopeptide symporter, conserved site [IPR018456]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase, RluC/RluD, conserved site [IPR006224]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APP", "ATAD1", "ATAD2", "ATG16L1", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BRD2", "BRPF1", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CHD5", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC2", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD2", "NSF", "NTHL1", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIK3C3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR2F", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRP8", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC15A4", "SLC1A5", "SLC27A4", "SLC2A1", "SLC37A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN6", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ACTL6A", "AHCYL1", "AKR1A1", "ALDH1A2", "ALDH2", "AP2M1", "AP3M1", "BLM", "CAPZA2", "CHD5", "DDT", "DDX10", "DDX17", "DDX18", "DDX24", "DDX3X", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DHX15", "DHX16", "DHX38", "DHX40", "DHX8", "DHX9", "DNM1L", "DRG2", "ECI2", "ERCC2", "HADH", "HGS", "HMOX2", "IDH2", "LBR", "MPP2", "MPP6", "MRPL3", "PFN1", "PI4KA", "POLR2B", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMD4", "RTCA", "STAM", "TOP2B", "TRIM21", "TSPAN6", "USP10", "USP19", "USP48"]}
interpro_domain/advanced/idx2term.json ADDED
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+ {}
interpro_domain/basic/idx2term.json ADDED
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+ {"0": "Importin-beta, N-terminal domain [IPR001494]", "1": "RNA recognition motif domain [IPR000504]", "2": "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "3": "Ubiquitin specific protease domain [IPR028889]", "4": "PDZ domain [IPR001478]", "5": "C2 domain [IPR000008]", "6": "Helicase-associated domain [IPR007502]", "7": "Domain of unknown function DUF1605 [IPR011709]", "8": "Glutathione S-transferase, C-terminal-like [IPR010987]", "9": "Zinc finger, RING-type [IPR001841]", "10": "Aminoacyl-tRNA synthetase, class II [IPR006195]"}
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+ version https://git-lfs.github.com/spec/v1
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+ oid sha256:3913d99cacee9189cd4654cc83d36c2fa85dbf7ac19f491bcf8437c4129ae712
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+ size 109859
interpro_domain/df_merge.tsv ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
2
+ TGS [IPR004095] 0 6 2.547732880034066 0.0108425457733432 2.9757281553398056 6.371359223300971 0.0599044240309401 0.6420468633844888 1.853727078466592 0.4881658729390138 0.7362131029634268 0.2857635897798585 0.0338360956076009 0.0666860823201616 0.1595576983806167 0.295251642909297
3
+ Cytochrome b5-like heme/steroid binding domain [IPR001199] 2 6 2.4367975646593187 0.0148179721936112 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 2.3666612945957126e-05 0.000188873280149 0.0027195691326621 0.0020183200628615
4
+ Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 2 7 2.3183974597565262 0.0204277299907724 2.9975728155339807 6.963592233009709 0.5006632403339694 0.4738825144563896 2.043814711463587 1.6869386038453082 0.907662015536667 0.3076020117251588 0.0034296220851759 0.0006712136127385 0.0090496486299172 0.0544656750173612
5
+ Guanylate kinase-like domain [IPR008144] 2 7 2.3183974597565262 0.0204277299907724 2.9975728155339807 6.963592233009709 0.5006632403339694 0.4738825144563896 2.043814711463587 1.6869386038453082 0.907662015536667 0.3076020117251588 0.0023758658868836 0.0003823532959252 0.0053269286919759 0.0338099842169397
6
+ Aminopeptidase N-like , N-terminal domain [IPR045357] 3 5 2.31123915999526 0.0208196484543454 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.000647621121882 0.0025659780541994 2.2860654433849456e-05 0.0003337445501144
7
+ Peptidase M1, membrane alanine aminopeptidase [IPR014782] 3 5 2.31123915999526 0.0208196484543454 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.000647621121882 0.0025659780541994 2.2860654433849456e-05 0.0003337445501144
interpro_domain/metrics.json ADDED
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+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3039,
4
+ "annotations_size": 2520,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.121031746031746
7
+ }
interpro_domain/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C295/C295_val_log2fc"}
interpro_domain/result.tsv ADDED
@@ -0,0 +1,241 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Isopropylmalate dehydrogenase-like domain [IPR024084] 0.969456027789264 2.4783145236048187 0.0132004723300833 0.9999999999999972 0.7448618926559275 4 P48735 1
3
+ Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.8589578455292826 2.4367975646593187 0.0148179721936112 1.0 0.7448618926559275 6 Q8WUJ1,Q9UMX5 2
4
+ Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.8357512090589146 2.3183974597565262 0.0204277299907724 1.0 0.7448618926559275 7 Q14168,Q9NZW5 2
5
+ Guanylate kinase-like domain [IPR008144] 0.8357512090589146 2.3183974597565262 0.0204277299907724 1.0 0.7448618926559275 7 Q14168,Q9NZW5 2
6
+ Aminopeptidase N-like , N-terminal domain [IPR045357] 0.8780810324560985 2.31123915999526 0.0208196484543454 1.0 0.7448618926559275 5 Q9UIQ6,P55786,P09960 3
7
+ Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.8780810324560985 2.31123915999526 0.0208196484543454 1.0 0.7448618926559275 5 Q9UIQ6,P55786,P09960 3
8
+ L27 domain [IPR004172] 0.9232185191114824 2.2994057073929812 0.0214819121607632 1.0 0.7448618926559275 4 Q14168,Q9NZW5 2
9
+ L27 domain, C-terminal [IPR014775] 0.9232185191114824 2.2994057073929812 0.0214819121607632 1.0 0.7448618926559275 4 Q14168,Q9NZW5 2
10
+ ERAP1-like C-terminal domain [IPR024571] 0.9232542819499374 1.911552540318657 0.0559336116516706 1.0 0.7448618926559275 3 Q9UIQ6,P55786 2
11
+ Peptidase M16, C-terminal [IPR007863] 0.7281626135099859 1.8366530174245457 0.0662611352299835 1.0 0.7448618926559275 7 P22695,Q5JRX3,O43847 3
12
+ Peptidase M16, N-terminal [IPR011765] 0.7281626135099859 1.8366530174245457 0.0662611352299835 1.0 0.7448618926559275 7 P22695,Q5JRX3,O43847 3
13
+ Zinc finger, CHHC-type [IPR012996] 0.8985507246376796 1.818055363443979 0.0690556713690537 1.0 0.7448618926559275 3 P55795,P31943 2
14
+ LEM domain [IPR003887] 0.7156313577071259 1.7989507831042546 0.0720264664169392 1.0 0.7448618926559275 6 Q8NC56 1
15
+ U-box domain [IPR003613] 0.7090028572410714 1.7684672757685425 0.0769828182546366 1.0 0.7448618926559275 6 P19474,Q7Z6E9 2
16
+ Peptidase M3A/M3B catalytic domain [IPR001567] 0.8761474631004136 1.7326928564969182 0.0831502748798374 1.0 0.7448618926559275 3 Q99797 1
17
+ DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.7739290897674953 1.6980338949105034 0.0895013647472362 1.0 0.7493744017449121 4 Q9HCE1,P51530 2
18
+ Biotin carboxylase, C-terminal [IPR005482] 0.7250506157531825 1.659622785281143 0.0969903616127783 1.0 0.7521804636930489 5 P05165,Q13085,Q96RQ3 3
19
+ Biotin carboxylase-like, N-terminal domain [IPR005481] 0.7250506157531825 1.659622785281143 0.0969903616127783 1.0 0.7521804636930489 5 P05165,Q13085,Q96RQ3 3
20
+ Biotin carboxylation domain [IPR011764] 0.7250506157531825 1.659622785281143 0.0969903616127783 1.0 0.7521804636930489 5 P05165,Q13085,Q96RQ3 3
21
+ Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479] 0.6843729984283082 1.6545415744351004 0.0980175233861704 1.0 0.7521804636930489 6 P05165,Q13085,Q96RQ3 3
22
+ TRAM/LAG1/CLN8 homology domain [IPR006634] 0.7399702945366098 1.556840204687043 0.1195084290653638 1.0 0.7553830932497286 4 Q96CP7,Q15629 2
23
+ Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.8195527616676135 1.5150285365607306 0.1297651775744122 1.0 0.7611085442515196 3 Q1KMD3 1
24
+ Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.7289731679434219 1.5108581988370249 0.13082458295173 1.0 0.7649140348917859 4 O15460,Q32P28 2
25
+ Rhodanese-like domain [IPR001763] 0.7958653225216465 1.423293450565809 0.1546511048050054 1.0 0.8060124608742893 3 Q8NCN5 1
26
+ SUN domain [IPR012919] 0.788702280580061 1.3955082635353848 0.1628626246347293 1.0 0.8110933924544161 3 O94901 1
27
+ Dual specificity protein phosphatase domain [IPR020422] 0.7004942339373914 1.391330412564073 0.1641252555839862 1.0 0.8110933924544161 4 Q8WUK0,P51452,Q99956 3
28
+ Dual specificity phosphatase, catalytic domain [IPR000340] 0.7004942339373914 1.391330412564073 0.1641252555839862 1.0 0.8110933924544161 4 Q8WUK0,P51452,Q99956 3
29
+ ATP-grasp fold [IPR011761] 0.6338496285499287 1.3772631875809658 0.1684308922170054 1.0 0.8169820055791615 8 P05165,Q13085,Q96RQ3 3
30
+ YTH domain [IPR007275] 0.6590017442210051 1.3676569377865258 0.1714194850135948 1.0 0.8202553336182367 5 Q9BYJ9 1
31
+ P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.6166745704132347 1.337141773320721 0.1811763638280088 1.0 0.8234754024416973 6 Q9HD20,P98194 2
32
+ Exoribonuclease, phosphorolytic domain 1 [IPR001247] 0.6517888691160669 1.3355553752533125 0.1816946441887204 1.0 0.8234754024416973 5 Q9NQT4,Q06265,Q5RKV6 3
33
+ Aminotransferase, class I/classII [IPR004839] 0.5988920861553353 1.253146923133584 0.2101522419954298 1.0 0.8452808223959218 6 Q6YP21,O75600,O15269 3
34
+ DNA2/NAM7 helicase, helicase domain [IPR041677] 0.7423894672704343 1.215744220430119 0.2240823732524619 1.0 0.8514685999328118 3 P51530 1
35
+ FAD dependent oxidoreductase [IPR006076] 0.6582031821736829 1.2131838921049276 0.2250595212150017 1.0 0.8514685999328118 4 Q8NCN5 1
36
+ BAG domain [IPR003103] 0.6538341834608745 1.1947780825714456 0.2321737457427652 1.0 0.8528831476264848 4 O95429 1
37
+ EXPERA domain [IPR033118] 0.9374382614422088 1.1832903437726436 0.2366940984248597 1.0 0.858228961195175 2 Q15125 1
38
+ FERM adjacent (FA) [IPR014847] 0.6503948513795019 1.1802929987826696 0.2378837017509787 1.0 0.8600673291427063 4 Q9HCM4 1
39
+ Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252] 0.7288939440659136 1.163453531138274 0.2446455413217836 1.0 0.8682209534834758 3 Q7L5N7 1
40
+ Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.9245966414224563 1.1377881200886033 0.2552089667878565 1.0 0.8817524768254691 2 O43390 1
41
+ CARG-binding factor, N-terminal [IPR012956] 0.9239380968060582 1.135459521564343 0.2561828328024198 1.0 0.8817524768254691 2 Q14103 1
42
+ Importin-beta, N-terminal domain [IPR001494] 0.60217342809882 1.135272447258201 0.2562611828507362 1.0 0.8817524768254691 13 O14980,O00410,O43592,Q92973,Q96P70,Q9HAV4 6
43
+ Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.9219624629568636 1.12847678119472 0.2591186173171809 1.0 0.8817524768254691 2 Q9Y282 1
44
+ Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.9219624629568636 1.12847678119472 0.2591186173171809 1.0 0.8817524768254691 2 Q9Y282 1
45
+ Exoribonuclease, phosphorolytic domain 2 [IPR015847] 0.6375918292163402 1.126420743658633 0.2599874705530069 1.0 0.8817524768254691 4 Q9NQT4,Q06265 2
46
+ Translation initiation factor, beta propellor-like domain [IPR013979] 0.6362851860478267 1.1209283160167076 0.2623183767184849 1.0 0.8825665011089212 4 Q96J01,Q9NV06 2
47
+ Anaphase-promoting complex subunit 4, WD40 domain [IPR024977] 0.5659624341748603 1.0976478861337766 0.2723582741223054 1.0 0.8912558392515665 6 Q96J01,Q9UNX4 2
48
+ RNA recognition motif domain [IPR000504] 0.2693502703952989 1.0492663955639012 0.2940555277740286 1.0 0.911453614768521 118 Q9P2K5,P51991,P22626,P35637,O14979,P52756,Q96T37,P55795,P31942,P52597,P14866,Q96PK6,P31943,Q9BWF3,P23246,Q14103,Q92804,O43390,Q8IZ69,O60506,Q99729,Q14011,Q13148,Q8WVV9,Q96EP5,Q96DH6 26
49
+ Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001] 0.8966084952255515 1.0393274089336493 0.2986524917338142 1.0 0.9142109784906186 2 Q9UJ83 1
50
+ Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766] 0.8966084952255515 1.0393274089336493 0.2986524917338142 1.0 0.9142109784906186 2 Q9UJ83 1
51
+ Thiamine pyrophosphate enzyme, central domain [IPR012000] 0.8966084952255515 1.0393274089336493 0.2986524917338142 1.0 0.9142109784906186 2 Q9UJ83 1
52
+ Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394] 0.5669474229050334 1.0224493029008843 0.3065682957673385 1.0 0.9240469331832448 10 O94966,Q93008,P51784,Q86UV5,Q14694,Q93009 6
53
+ Ubiquitin specific protease domain [IPR028889] 0.5669474229050334 1.0224493029008843 0.3065682957673385 1.0 0.9240469331832448 10 O94966,Q93008,P51784,Q86UV5,Q14694,Q93009 6
54
+ Small-subunit processome, Utp12 [IPR007148] 0.6762187088274009 0.960971110939776 0.3365666936167428 1.0 0.9343733087364676 3 Q9UNX4,Q15269 2
55
+ Protein kinase, C-terminal [IPR017892] 0.5643130593110708 0.947161596830704 0.343556440980854 1.0 0.9352976244101092 5 Q05655 1
56
+ PTBP1, RNA recognition motif 2-like [IPR021790] 0.5936001651415505 0.9425671899288608 0.345902328644557 1.0 0.9362769797897784 4 Q8WVV9 1
57
+ Reticulon [IPR003388] 0.6673254281950065 0.9272006527939888 0.3538223639723217 1.0 0.9465311647667204 3 Q9NQC3,Q16799 2
58
+ Calcineurin-like phosphoesterase domain, ApaH type [IPR004843] 0.5328617436293238 0.921742902761424 0.3566626962822914 1.0 0.9480907116364709 7 Q9BRF8,P62140 2
59
+ Glutamine amidotransferase [IPR017926] 0.5871499176276617 0.9158783036993016 0.3597307275667138 1.0 0.9502986208236044 4 Q9NRF8,P17812,P49915 3
60
+ FAD/NAD(P)-binding domain [IPR023753] 0.5564729794304901 0.9128084037586648 0.3613433177038949 1.0 0.9502986208236044 5 Q16881,O95831,P22570 3
61
+ CBS domain [IPR000644] 0.552087564420995 0.8936586045303567 0.3715045800704089 1.0 0.95620352704002 5 Q8NE01,P51798,P54619 3
62
+ ABC transporter type 1, transmembrane domain [IPR011527] 0.5497810047022921 0.8836072557882735 0.3769082608561414 1.0 0.9594028458156326 5 Q03518,O75027 2
63
+ AGC-kinase, C-terminal [IPR000961] 0.5213776852886038 0.8685444355531713 0.3850963575520016 1.0 0.9695775290358004 7 P31751,Q05655 2
64
+ Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.8409614751399382 0.8478916291705476 0.3964983268035644 1.0 0.9767114208650854 2 O15460 1
65
+ SUN coiled coil domain 2 [IPR040994] 0.8373394797497502 0.8356999518135125 0.4033237223944121 1.0 0.98019023891183 2 O94901 1
66
+ Zinc finger, RanBP2-type [IPR001876] 0.5173192207276381 0.8108419109798445 0.4174564626933603 1.0 0.9832681747742936 9 P35637,Q92804 2
67
+ Brix domain [IPR007109] 0.558640960596553 0.7992276938575814 0.4241583965127646 1.0 0.9878735297709492 4 Q8TDN6,Q9NQ55 2
68
+ Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378] 0.5580097401186165 0.7966738125446611 0.4256404967067069 1.0 0.989496357657658 4 Q9NVN8 1
69
+ S1 domain [IPR003029] 0.4935858165803481 0.7617571893324512 0.446204935649483 1.0 0.9979604865066264 6 Q7KZ85,P62487 2
70
+ Acyl-CoA oxidase, C-terminal [IPR002655] 0.8083635166282424 0.7397068996125717 0.4594778606486527 1.0 0.9979604865066264 2 O15254 1
71
+ RNA-binding domain, S1 [IPR022967] 0.4918176958188225 0.7338220222481924 0.4630572168564721 1.0 0.9979604865066264 7 Q7KZ85,Q14562,P62487 3
72
+ Phospholipid/glycerol acyltransferase [IPR002123] 0.4916043281714991 0.7328639748295905 0.4636413973078399 1.0 0.9979604865066264 7 Q9HCL2,Q7L5N7 2
73
+ Mad3/Bub1 homology region 1 [IPR013212] 0.7955218966084887 0.6981585233064457 0.4850780620007935 1.0 0.9979604865066264 2 O60566 1
74
+ Ubiquitin-conjugating enzyme E2 [IPR000608] 0.4971322216754148 0.6837488481351122 0.4941337719840082 1.0 0.9979604865066264 11 P49427,Q7Z7E8,P60604 3
75
+ B30.2/SPRY domain [IPR001870] 0.4916690120998879 0.6771112760102079 0.4983353550705707 1.0 0.9979604865066264 10 Q1KMD3,Q9BUJ2,P19474 3
76
+ SPRY domain [IPR003877] 0.4916690120998879 0.6771112760102079 0.4983353550705707 1.0 0.9979604865066264 10 Q1KMD3,Q9BUJ2,P19474 3
77
+ Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846] 0.5968379446640325 0.6675645298933324 0.5044116055864447 1.0 0.9979604865066264 3 Q16531,Q10570 2
78
+ Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871] 0.5968379446640325 0.6675645298933324 0.5044116055864447 1.0 0.9979604865066264 3 Q16531,Q10570 2
79
+ CRAL-TRIO lipid binding domain [IPR001251] 0.5958473011660501 0.6640532574172814 0.5066562253141145 1.0 0.9979604865066264 3 Q8NHP6 1
80
+ Exportin-2, central domain [IPR013713] 0.5957995764871561 0.6638842220020322 0.5067644153912529 1.0 0.9979604865066264 3 O15397 1
81
+ Ataxin-2, C-terminal [IPR009818] 0.4906374865170588 0.6328925880058444 0.5268037883687151 1.0 0.9979604865066264 5 Q9BPZ3 1
82
+ Peptidase M48 [IPR001915] 0.7744484688837586 0.6315330090562682 0.5276920731797383 1.0 0.9979604865066264 2 Q96E52 1
83
+ Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.7731313796509662 0.6274388645554597 0.5303715987042001 1.0 0.9979604865066264 2 P51116 1
84
+ SH2 domain [IPR000980] 0.4781920710921846 0.6181875202213472 0.536451735545902 1.0 0.9979604865066264 10 P42224,Q7KZ85,Q06124 3
85
+ Nucleotidyl transferase domain [IPR005835] 0.7662166611787942 0.606089132501675 0.5444555670575517 1.0 0.9979604865066264 2 Q9Y5P6 1
86
+ Glutathione S-transferase, C-terminal [IPR004046] 0.4702537423970313 0.6015530053652772 0.5474717187816796 1.0 0.9979604865066264 9 P21266,O43324 2
87
+ Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186] 0.4828634433411968 0.6013121537383175 0.5476320960810135 1.0 0.9979604865066264 5 O00743,P62140 2
88
+ Serine-threonine protein phosphatase, N-terminal [IPR031675] 0.7642410273295922 0.6000348512563447 0.5484830091508814 1.0 0.9979604865066264 2 P62140 1
89
+ Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364] 0.5069266645545781 0.5959371173468548 0.5512172359641632 1.0 0.9979604865066264 4 O43776 1
90
+ Glutamine amidotransferase type 2 domain [IPR017932] 0.5740178764909036 0.587990359501303 0.55653876370595 1.0 0.9979604865066264 3 P08243 1
91
+ Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.4570664381150806 0.5814692921323936 0.5609242085443289 1.0 0.9979604865066264 7 P42356,Q9BTU6 2
92
+ Histone deacetylase domain [IPR023801] 0.755021402700035 0.5720607899546337 0.5672807917244809 1.0 0.9979604865066264 2 Q92769 1
93
+ DZF domain [IPR006561] 0.497228417155912 0.5595069090162729 0.575815817331524 1.0 0.9979604865066264 4 Q12905,Q96SI9 2
94
+ RNA-binding S4 domain [IPR002942] 0.564832131167872 0.5568084325393573 0.5776583218394054 1.0 0.9979604865066264 3 Q9NV31 1
95
+ PurM-like, C-terminal domain [IPR010918] 0.5634581966947572 0.5521905327203975 0.5808178200187806 1.0 0.9979604865066264 3 P22102 1
96
+ Endonuclease/exonuclease/phosphatase [IPR005135] 0.5629282209286219 0.5504125456469902 0.5820364456950151 1.0 0.9979604865066264 3 Q6L8Q7 1
97
+ Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791] 0.7471188673032628 0.5484645751263999 0.5833729470134721 1.0 0.9979604865066264 2 Q9H993 1
98
+ Potassium channel tetramerisation-type BTB domain [IPR003131] 0.7458017780704667 0.5445674687676555 0.5860510337649723 1.0 0.9979604865066264 2 Q9NXV2 1
99
+ RNA 3'-terminal phosphate cyclase domain [IPR023797] 0.7454725057622591 0.5435948128526132 0.5867203300652253 1.0 0.9979604865066264 2 O00442 1
100
+ RNA 3'-terminal phosphate cyclase, insert domain [IPR013791] 0.7454725057622591 0.5435948128526132 0.5867203300652253 1.0 0.9979604865066264 2 O00442 1
101
+ CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.7355943365162936 0.5147237142873382 0.6067460996546763 1.0 0.9979604865066264 2 Q9NUQ9 1
102
+ RNA polymerase Rpb2, domain 7 [IPR007641] 0.7352650642081013 0.5137718484427041 0.6074115122781276 1.0 0.9979604865066264 2 P30876 1
103
+ RNA polymerase Rpb2, domain 3 [IPR007645] 0.7352650642081013 0.5137718484427041 0.6074115122781276 1.0 0.9979604865066264 2 P30876 1
104
+ RNA polymerase, beta subunit, protrusion [IPR007644] 0.7352650642081013 0.5137718484427041 0.6074115122781276 1.0 0.9979604865066264 2 P30876 1
105
+ DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120] 0.7352650642081013 0.5137718484427041 0.6074115122781276 1.0 0.9979604865066264 2 P30876 1
106
+ RNA polymerase Rpb2, domain 2 [IPR007642] 0.7352650642081013 0.5137718484427041 0.6074115122781276 1.0 0.9979604865066264 2 P30876 1
107
+ MENTAL domain [IPR019498] 0.7299967072769051 0.4986369816932965 0.6180351472368364 1.0 0.9979604865066264 2 Q14849 1
108
+ Sec63 domain [IPR004179] 0.5471014492753598 0.4982049616583276 0.6183395856689804 1.0 0.9979604865066264 3 Q9UGP8,Q8N3C0 2
109
+ Target SNARE coiled-coil homology domain [IPR000727] 0.4565677345597879 0.4944148408745771 0.6210132349866382 1.0 0.9979604865066264 12 O15155,Q9UEU0,P56962 3
110
+ OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365] 0.4555192674173213 0.4938601329865793 0.6214049616686834 1.0 0.9979604865066264 5 O43776 1
111
+ Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.4398553454452613 0.4918979264821125 0.6227915042050447 1.0 0.9979604865066264 8 Q32P28,O15460 2
112
+ Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.4398553454452613 0.4918979264821125 0.6227915042050447 1.0 0.9979604865066264 8 Q32P28,O15460 2
113
+ PDZ domain [IPR001478] 0.482738391550771 0.4792166069500568 0.6317845411444489 1.0 0.9979604865066264 21 O00560,Q6ZWJ1,Q14168,P57105,Q5T2T1,Q9NZW5 6
114
+ Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346] 0.7224234441883371 0.4772018056247706 0.6332184254896869 1.0 0.9979604865066264 2 Q93009 1
115
+ Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615] 0.7224234441883362 0.4772018056247687 0.6332184254896882 1.0 0.9979604865066264 2 Q86UV5 1
116
+ C2 domain [IPR000008] 0.4577815888337606 0.4553016762082765 0.6488922205133125 1.0 0.9979604865066264 15 Q96J02,Q96PU5,Q96PE3,Q9BSJ8,Q05655 5
117
+ FAD-binding domain, ferredoxin reductase-type [IPR017927] 0.7085940072439921 0.4390858760411133 0.6605993127390928 1.0 0.9979604865066264 2 P00387 1
118
+ Oxidoreductase FAD/NAD(P)-binding [IPR001433] 0.7085940072439921 0.4390858760411133 0.6605993127390928 1.0 0.9979604865066264 2 P00387 1
119
+ Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709] 0.7085940072439921 0.4390858760411133 0.6605993127390928 1.0 0.9979604865066264 2 P00387 1
120
+ Zinc finger, CCHC-type [IPR001878] 0.4261972613992141 0.4374343779722043 0.6617963569763075 1.0 0.9979604865066264 8 Q9NUD5,Q9BWF3 2
121
+ RQC domain [IPR018982] 0.7053012841620037 0.4302148114983951 0.6670393886817019 1.0 0.9979604865066264 2 P54132 1
122
+ ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284] 0.7053012841620037 0.4302148114983951 0.6670393886817019 1.0 0.9979604865066264 2 P54132 1
123
+ Helicase-associated domain [IPR007502] 0.4290583770605113 0.4013697444148476 0.6881479214878958 1.0 0.9979604865066264 11 Q08211,O43143,Q9H2U1,Q8IX18,O60231,Q14562,Q92620 7
124
+ Domain of unknown function DUF1605 [IPR011709] 0.4290583770605113 0.4013697444148476 0.6881479214878958 1.0 0.9979604865066264 11 Q08211,O43143,Q9H2U1,Q8IX18,O60231,Q14562,Q92620 7
125
+ Serine hydroxymethyltransferase-like domain [IPR039429] 0.6924596641422461 0.3964059755594103 0.6918055585363567 1.0 0.9979604865066264 2 P34897 1
126
+ 3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.6842278564372745 0.3754190787975383 0.707348817981625 1.0 0.9979604865066264 2 Q16836 1
127
+ 3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.6842278564372745 0.3754190787975383 0.707348817981625 1.0 0.9979604865066264 2 Q16836 1
128
+ KHDRBS, Qua1 domain [IPR032571] 0.6829107672044705 0.3721125314258617 0.7098090665078758 1.0 0.9979604865066264 2 O75525 1
129
+ Sam68, tyrosine-rich domain [IPR032335] 0.6829107672044705 0.3721125314258617 0.7098090665078758 1.0 0.9979604865066264 2 O75525 1
130
+ Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 0.4166835968788691 0.3536620273759021 0.7235921834362711 1.0 0.9979604865066264 5 Q05655 1
131
+ R3H domain [IPR001374] 0.49933732470761 0.3528966755887018 0.7241659031976913 1.0 0.9979604865066264 3 O95453 1
132
+ Domain of unknown function DUF4217 [IPR025313] 0.6733618702667046 0.3485751046643273 0.7274083204224344 1.0 0.9979604865066264 2 Q9NVP1 1
133
+ JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.4004342715736217 0.3408676270146138 0.7332032367456494 1.0 0.9979604865066264 8 Q6P2Q9,Q92905,O00303 3
134
+ Glutaredoxin [IPR002109] 0.4315309192926476 0.3340199913838267 0.7383644732488623 1.0 0.9979604865066264 4 Q16881,O76003 2
135
+ NLE [IPR012972] 0.6648007902535349 0.3281393369894446 0.7428063125143067 1.0 0.9979604865066264 2 Q9GZL7 1
136
+ Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763] 0.4286876168822216 0.3252918384638615 0.7449602072460606 1.0 0.9979604865066264 4 Q13085 1
137
+ Acetyl-CoA carboxylase [IPR034733] 0.4286876168822216 0.3252918384638615 0.7449602072460606 1.0 0.9979604865066264 4 Q13085 1
138
+ Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762] 0.4286876168822216 0.3252918384638615 0.7449602072460606 1.0 0.9979604865066264 4 Q13085 1
139
+ Acetyl-CoA carboxylase, central domain [IPR013537] 0.6618373394797411 0.321216150224343 0.7480465940286127 1.0 0.9979604865066264 2 Q13085 1
140
+ Transcription elongation factor S-II, central domain [IPR003618] 0.486495388669292 0.3175314892625323 0.7508403497783891 1.0 0.9979604865066264 3 Q92576,P23193 2
141
+ 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154] 0.658215344089549 0.3128616100763335 0.7543858051192047 1.0 0.9979604865066264 2 Q49A26 1
142
+ Glutaredoxin, PICOT-like [IPR033658] 0.6542640763911729 0.3038835313385951 0.7612166249308956 1.0 0.9979604865066264 2 O76003 1
143
+ Exportin-1/Importin-beta-like [IPR013598] 0.4212831420839027 0.3030369798507488 0.7618616799286491 1.0 0.9979604865066264 4 O14980,O43592 2
144
+ Peptidase S9A, N-terminal domain [IPR023302] 0.643398090220598 0.2799393726905509 0.7795240193179442 1.0 0.9979604865066264 2 Q4J6C6 1
145
+ CCAAT-binding factor [IPR005612] 0.4703557312252859 0.2756389114867565 0.7828254199294253 1.0 0.9979604865066264 3 Q8WTT2,Q03701 2
146
+ PITH domain [IPR010400] 0.6394468225222223 0.2715084056031109 0.7860000356934447 1.0 0.9979604865066264 2 O43396 1
147
+ Glutathione S-transferase, C-terminal-like [IPR010987] 0.3911460776920509 0.2676386057370788 0.7889775115772824 1.0 0.9979604865066264 11 Q8TB36,O43324,Q9Y696,P21266,O43708,P26640 6
148
+ S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878] 0.635166282515638 0.2625437593889516 0.7929022530533658 1.0 0.9979604865066264 2 O43865 1
149
+ Fxr1, tudor domain [IPR041560] 0.4650062053770143 0.2624142974331266 0.7930020510477827 1.0 0.9979604865066264 3 P51116 1
150
+ Fragile X-related 1 protein, C-terminal core [IPR022034] 0.4650062053770143 0.2624142974331266 0.7930020510477827 1.0 0.9979604865066264 3 P51116 1
151
+ Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.4650062053770143 0.2624142974331266 0.7930020510477827 1.0 0.9979604865066264 3 P51116 1
152
+ Agenet-like domain [IPR008395] 0.4650062053770143 0.2624142974331266 0.7930020510477827 1.0 0.9979604865066264 3 P51116 1
153
+ Pleckstrin homology domain [IPR001849] 0.4304474335445174 0.2563573586657816 0.7976749107315102 1.0 0.9979604865066264 24 Q96P47,Q96SU4,Q8IYI6,P31751 4
154
+ Ribosomal protein S4/S9, N-terminal [IPR001912] 0.630556470200849 0.2530879766065828 0.8002002297697128 1.0 0.9979604865066264 2 Q9NV31 1
155
+ Far upstream element-binding protein, C-terminal [IPR015096] 0.629239380968053 0.2504244114488624 0.802259153304183 1.0 0.9979604865066264 2 Q92945 1
156
+ Valyl tRNA synthetase, anticodon-binding domain [IPR033705] 0.6256173855778684 0.2431874677730433 0.8078601747670571 1.0 0.9979604865066264 2 P26640 1
157
+ F-BAR domain [IPR031160] 0.6219953901876731 0.236080097411383 0.8133705174452792 1.0 0.9979604865066264 2 Q9UNF0 1
158
+ FCH domain [IPR001060] 0.6219953901876731 0.236080097411383 0.8133705174452792 1.0 0.9979604865066264 2 Q9UNF0 1
159
+ 26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135] 0.6203490286466853 0.2328925395630199 0.8158448517432504 1.0 0.9979604865066264 2 Q13098 1
160
+ Metaxin, glutathione S-transferase domain [IPR033468] 0.6190319394138855 0.2303619449882183 0.8178105294800739 1.0 0.9979604865066264 2 Q13505 1
161
+ Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.6190319394138855 0.2303619449882183 0.8178105294800739 1.0 0.9979604865066264 2 Q13505 1
162
+ OCRE domain [IPR041591] 0.4506642206521128 0.2286591759739979 0.819133826999253 1.0 0.9979604865066264 3 P52756 1
163
+ DNA topoisomerase 2, TOPRIM domain [IPR034157] 0.6180441224892931 0.2284753700344731 0.8192767016491114 1.0 0.9979604865066264 2 Q02880 1
164
+ TOPRIM domain [IPR006171] 0.6180441224892931 0.2284753700344731 0.8192767016491114 1.0 0.9979604865066264 2 Q02880 1
165
+ DTHCT [IPR012542] 0.6180441224892931 0.2284753700344731 0.8192767016491114 1.0 0.9979604865066264 2 Q02880 1
166
+ C-terminal associated domain of TOPRIM [IPR031660] 0.6180441224892931 0.2284753700344731 0.8192767016491114 1.0 0.9979604865066264 2 Q02880 1
167
+ DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506] 0.6180441224892931 0.2284753700344731 0.8192767016491114 1.0 0.9979604865066264 2 Q02880 1
168
+ DNA topoisomerase, type IIA, domain A [IPR002205] 0.6180441224892931 0.2284753700344731 0.8192767016491114 1.0 0.9979604865066264 2 Q02880 1
169
+ Acyl-CoA-binding protein, ACBP [IPR000582] 0.6131050378663094 0.2191892287545701 0.826502645693185 1.0 0.9979604865066264 2 O75521 1
170
+ Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.3805601317957101 0.1940583999441149 0.8461301544009947 1.0 0.9979604865066264 4 P16615,P98194,P05023 3
171
+ Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.3805601317957101 0.1940583999441149 0.8461301544009947 1.0 0.9979604865066264 4 P16615,P98194,P05023 3
172
+ Nop domain [IPR002687] 0.4337944664031574 0.1922470329447498 0.8475487059828946 1.0 0.9979604865066264 3 Q8WWY3,Q9Y2X3 2
173
+ NOSIC [IPR012976] 0.4337944664031574 0.1922470329447498 0.8475487059828946 1.0 0.9979604865066264 3 Q8WWY3,Q9Y2X3 2
174
+ Mu homology domain [IPR028565] 0.3792421746293266 0.1909389172323358 0.8485734495049482 1.0 0.9979604865066264 4 Q9BXS5,Q96CW1,Q9Y2T2 3
175
+ SAB domain [IPR007477] 0.4331357048748224 0.1908993372706954 0.8486044594066036 1.0 0.9979604865066264 3 Q9Y2J2,P11171 2
176
+ Band 4.1, C-terminal [IPR008379] 0.4331357048748224 0.1908993372706954 0.8486044594066036 1.0 0.9979604865066264 3 Q9Y2J2,P11171 2
177
+ Zinc finger, UBP-type [IPR001607] 0.5870925255185961 0.1743664747578819 0.8615774599532973 1.0 0.9979604865066264 2 Q53GS9 1
178
+ Methylglyoxal synthase-like domain [IPR011607] 0.5867632532103964 0.1738434340490408 0.8619885086401335 1.0 0.9979604865066264 2 P31939 1
179
+ SH3 domain [IPR001452] 0.4204242314300277 0.1705714626668174 0.8645607385304601 1.0 0.9979604865066264 32 Q14168,Q9NZW5,Q5T2T1,Q9UQB8 4
180
+ Tudor domain [IPR002999] 0.3376806697673858 0.1599106929689951 0.8729514251476231 1.0 0.9979604865066264 7 Q14739 1
181
+ PurM-like, N-terminal domain [IPR016188] 0.5709581824168525 0.1500435395964747 0.8807302644299269 1.0 0.9979604865066264 2 P22102 1
182
+ FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.3452683191013673 0.1477128260920188 0.8825694089249732 1.0 0.9979604865066264 10 P62942,O95302,Q96AY3 3
183
+ Biotin/lipoyl attachment [IPR000089] 0.3402462040606625 0.1453558458979767 0.884429924212982 1.0 0.9979604865066264 9 P05165,Q13085,Q96RQ3 3
184
+ Kinesin-like [IPR022164] 0.4084321475625833 0.1444828812218924 0.8851191734187898 1.0 0.9979604865066264 3 Q9Y3P9,Q9NQT8 2
185
+ Aldehyde dehydrogenase domain [IPR015590] 0.3395154302128939 0.1435737524345514 0.8858370684052879 1.0 0.9979604865066264 9 P05091,O94788 2
186
+ Glutathione S-transferase, N-terminal [IPR004045] 0.3309134685256475 0.1430337897033443 0.8862634952258799 1.0 0.9979604865066264 7 P21266,Q8TB36 2
187
+ Intermediate filament head, DNA-binding domain [IPR006821] 0.355760748302857 0.139938632237271 0.8887084774794389 1.0 0.9979604865066264 4 P07196 1
188
+ CS domain [IPR007052] 0.3335096251342854 0.129329984296476 0.8970965466262368 1.0 0.9979604865066264 9 O94966,Q9P035 2
189
+ SNF2, N-terminal [IPR000330] 0.3511476144407998 0.1250826507514848 0.9004581181132667 1.0 0.9979604865066264 14 Q9H4L7,Q2NKX8 2
190
+ Dynamin stalk domain [IPR000375] 0.5446163977609377 0.116002228570035 0.9076507755779322 1.0 0.9979604865066264 2 O00429 1
191
+ Dynamin GTPase effector [IPR003130] 0.5446163977609377 0.116002228570035 0.9076507755779322 1.0 0.9979604865066264 2 O00429 1
192
+ GTPase effector domain [IPR020850] 0.5446163977609377 0.116002228570035 0.9076507755779322 1.0 0.9979604865066264 2 O00429 1
193
+ CAP Gly-rich domain [IPR000938] 0.3398366563535489 0.110386924739737 0.91210252230224 1.0 0.9979604865066264 4 Q99426 1
194
+ Zinc finger, RING-type [IPR001841] 0.3677934694153126 0.1093019897687337 0.9129629684456388 1.0 0.9979604865066264 21 O94822,Q9UBS8,P19474,Q86UK7,O96028,Q7Z6E9 6
195
+ N-acetylgalactosaminyltransferase [IPR045885] 0.5344089562067735 0.1046526192582148 0.9166514597781918 1.0 0.9979604865066264 2 Q10471 1
196
+ WWE domain [IPR004170] 0.3701242493842089 0.0884845492563764 0.9294915640752192 1.0 0.9979604865066264 3 Q14669 1
197
+ Rab-GTPase-TBC domain [IPR000195] 0.3083300656217745 0.0785485179391053 0.9373917376752364 1.0 0.9979604865066264 5 Q8TC07 1
198
+ Chromo domain subgroup [IPR017984] 0.3567193675889379 0.0733450416666891 0.9415315501264254 1.0 0.9979604865066264 3 P83916,P45973 2
199
+ Chromo shadow domain [IPR008251] 0.3567193675889379 0.0733450416666891 0.9415315501264254 1.0 0.9979604865066264 3 P83916,P45973 2
200
+ CSN8/PSMD8/EIF3K [IPR033464] 0.3550724637681214 0.0716367002253611 0.9428910325354328 1.0 0.9979604865066264 3 Q9UBQ5,P48556 2
201
+ TOG domain [IPR034085] 0.2946514517299449 0.0683193280327519 0.9455314385298546 1.0 0.9979604865066264 7 O00410 1
202
+ rRNA-processing arch domain [IPR025696] 0.4896279222917212 0.0660881642036611 0.947307633847918 1.0 0.9979604865066264 2 P42285 1
203
+ ATP-dependent RNA helicase Ski2, C-terminal [IPR012961] 0.4896279222917212 0.0660881642036611 0.947307633847918 1.0 0.9979604865066264 2 P42285 1
204
+ Proteasome alpha-subunit, N-terminal domain [IPR000426] 0.2926427651779503 0.0649562243214165 0.9482088545365208 1.0 0.9979604865066264 7 P25789,P25788 2
205
+ MPN domain [IPR037518] 0.3021306729016313 0.0599283289516018 0.9522127171966288 1.0 0.9979604865066264 10 Q6P2Q9,Q92905,O00303 3
206
+ Clp ATPase, C-terminal [IPR019489] 0.4790912084293638 0.0594277979019438 0.9526113726567712 1.0 0.9979604865066264 2 Q9H078 1
207
+ Aminoacyl-tRNA synthetase, class II [IPR006195] 0.303500660501979 0.0556921614603989 0.9555870440609288 1.0 0.9979604865066264 11 Q15046,Q9BW92,Q9Y285,O43776,P26639,P41250,P07814,P14868,Q9NP81,Q6PI48 10
208
+ Guanylate-binding protein, N-terminal [IPR015894] 0.4715179453407854 0.0551439097367079 0.9560238144304634 1.0 0.9979604865066264 2 Q6DD88 1
209
+ Guanylate-binding protein/Atlastin, C-terminal [IPR003191] 0.4715179453407854 0.0551439097367079 0.9560238144304634 1.0 0.9979604865066264 2 Q6DD88 1
210
+ GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386] 0.4715179453407854 0.0551439097367079 0.9560238144304634 1.0 0.9979604865066264 2 Q6DD88 1
211
+ Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553] 0.298638207037943 0.0544386693236836 0.9565856708522764 1.0 0.9979604865066264 10 O95782 1
212
+ Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481] 0.4692130391833997 0.0539198282494904 0.9569990389862636 1.0 0.9979604865066264 2 Q96KP1 1
213
+ GTP binding protein, second domain [IPR031662] 0.4685544945669995 0.0535767500692031 0.9572723806573862 1.0 0.9979604865066264 2 P55039 1
214
+ Thioesterase domain [IPR006683] 0.4659203161014028 0.0522336221841846 0.958342542861315 1.0 0.9979604865066264 2 Q9NPJ3 1
215
+ TIP49, P-loop domain [IPR010339] 0.4540665130062434 0.0467450859872465 0.9627163961777404 1.0 0.9979604865066264 2 Q9Y265 1
216
+ RuvB-like, AAA-lid domain [IPR041048] 0.4540665130062434 0.0467450859872465 0.9627163961777404 1.0 0.9979604865066264 2 Q9Y265 1
217
+ Aminotransferase class V domain [IPR000192] 0.4527494237734566 0.0461889939274576 0.963159614686987 1.0 0.9979604865066264 2 Q9Y617 1
218
+ Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846] 0.4514323345406524 0.045643214101816 0.963594625172464 1.0 0.9979604865066264 2 Q96G03 1
219
+ Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845] 0.4514323345406524 0.045643214101816 0.963594625172464 1.0 0.9979604865066264 2 Q96G03 1
220
+ Rpn11/EIF3F, C-terminal [IPR024969] 0.2911922681026207 0.0449458344236653 0.9641504831494472 1.0 0.9979604865066264 4 O00303 1
221
+ Fumarylacetoacetase-like, C-terminal [IPR011234] 0.44879815607507 0.044582113132627 0.964440400135082 1.0 0.9979604865066264 2 Q6P587 1
222
+ Threonine-tRNA ligase catalytic core domain [IPR033728] 0.4481396114586706 0.0443230962780426 0.964646861595522 1.0 0.9979604865066264 2 Q9BW92 1
223
+ Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030] 0.4385907145209057 0.0408377573151789 0.967425238468664 1.0 0.9979604865066264 2 P21399 1
224
+ Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573] 0.4385907145209057 0.0408377573151789 0.967425238468664 1.0 0.9979604865066264 2 P21399 1
225
+ NOP5, N-terminal [IPR012974] 0.4336516298979206 0.0392240949910321 0.968711723390929 1.0 0.9979604865066264 2 Q9Y2X3 1
226
+ ELM2 domain [IPR000949] 0.431017451432326 0.0384132409751397 0.9693582040027786 1.0 0.9979604865066264 2 Q13330 1
227
+ Metastasis-associated protein MTA1, R1 domain [IPR035170] 0.431017451432326 0.0384132409751397 0.9693582040027786 1.0 0.9979604865066264 2 Q13330 1
228
+ Plectin/S10, N-terminal [IPR005326] 0.4280540006585348 0.0375409137123653 0.970053718698833 1.0 0.9979604865066264 2 Q15149 1
229
+ Ataxin 2, SM domain [IPR025852] 0.4237734606519528 0.0363528364978248 0.971001020321716 1.0 0.9979604865066264 2 Q99700 1
230
+ LsmAD domain [IPR009604] 0.4237734606519528 0.0363528364978248 0.971001020321716 1.0 0.9979604865066264 2 Q99700 1
231
+ Acyltransferase, C-terminal domain [IPR032098] 0.423114916035555 0.0361773858761995 0.9711409176399026 1.0 0.9979604865066264 2 Q9NUQ2 1
232
+ Kinesin-like KIF1-type [IPR022140] 0.408297662166611 0.0327090489705128 0.973906607718777 1.0 0.9981429864189932 2 Q9NQT8 1
233
+ Kinesin-associated [IPR032405] 0.408297662166611 0.0327090489705128 0.973906607718777 1.0 0.9981429864189932 2 Q9NQT8 1
234
+ EF hand associated, type-2 [IPR013567] 0.3598946328613774 0.0262883942058413 0.9790273117957516 1.0 0.9989642052620736 2 Q8IXI2 1
235
+ EF hand associated, type-1 [IPR013566] 0.3598946328613774 0.0262883942058413 0.9790273117957516 1.0 0.9989642052620736 2 Q8IXI2 1
236
+ MIRO domain [IPR020860] 0.3598946328613774 0.0262883942058413 0.9790273117957516 1.0 0.9989642052620736 2 Q8IXI2 1
237
+ Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099] 0.2875260902394246 0.0262397318201573 0.9790661253728457 1.0 0.9989642052620736 3 Q16881 1
238
+ 60S ribosomal protein L10P, insertion domain [IPR040637] 0.3516628251564067 0.0257202902040677 0.9794804399672186 1.0 0.9989642052620736 2 P05388 1
239
+ mRNA splicing factor Cwf21 domain [IPR013170] 0.3510042805400079 0.0256794964077555 0.9795129779602756 1.0 0.9989642052620736 2 O15042 1
240
+ FYVE zinc finger [IPR000306] 0.2641494845931819 0.023160842842929 0.981521973106704 1.0 0.9989642052620736 4 Q9P2R3,Q96T51 2
241
+ Zinc finger, FYVE-related [IPR017455] 0.2641494845931819 0.023160842842929 0.981521973106704 1.0 0.9989642052620736 4 Q9P2R3,Q96T51 2
interpro_domain/selections.json ADDED
The diff for this file is too large to render. See raw diff
 
interpro_family/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_family/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "Mitochondrial carrier protein [IPR002067]", "2": "Glutathione Transferase family [IPR040079]"}
interpro_family/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: af819e8a1d9509cec2624cbf18c9c4a09bd14429e3e0c9fb06a97ce90ffee580
  • Pointer size: 131 Bytes
  • Size of remote file: 143 kB