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23edeea verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Response of eif2ak4 gcn2 to amino acid deficiency 0.5815395056330692 4.247038347424837 2.1661489539415157e-05 0.0297240677931796 0.0277578876434267 75 P27635,P62280,P46776,P08865,P83881,P61353,Q07020,P46778,Q92616,P05388,P18077,Q9Y3U8,P61247,P84098,P30050,P18124,P35268,P62266,P62277,P62841,P32969,P61313,P62701,P61513,P62829,P62910,P05198,P18621,P36578,P62241,P39019,P46781,P62244,P63220,P15880,P39023,P49207,Q02543,P62753,P62424,P62249,P40429,P61927,P26373 44
Eukaryotic translation elongation 0.5697544718700248 4.108327954002083 3.985339216572292e-05 0.0540039463556115 0.0277578876434267 76 P27635,P62280,P46776,P08865,P83881,P61353,Q07020,P46778,P05388,P18077,Q9Y3U8,P61247,P84098,P30050,P18124,P35268,P62266,P62277,P62841,P32969,P61313,P62701,Q05639,P61513,P62829,P62910,P18621,P36578,P62241,P39019,P46781,P13639,P62244,P63220,P15880,P39023,P49207,Q02543,P62753,P62424,P62249,P40429,P61927,P26373 44
Srp dependent cotranslational protein targeting to membrane 0.561105180012212 3.817247768428528 0.0001349486336201 0.1713820875375665 0.0626611488776373 90 P27635,P46776,P62280,P08865,P83881,Q07020,P61353,Q9UHB9,P46778,P05388,P61619,P18077,Q9Y3U8,P61009,P61247,P84098,O76094,P30050,P35268,P18124,P62266,P62277,P62841,P32969,P61313,P62701,P61513,P62829,P62910,P67812,P60468,P18621,P36578,P62241,P39019,P46781,P62244,Q9UNL2,P63220,P15880,P39023,P49207,Q02543,P62753,P62424,P62249,P40429,P61927,P26373 49
Selenoamino acid metabolism 0.5411335121113714 3.6260488609802057 0.000287790923001 0.3303167592957012 0.0807981110523117 88 P27635,P46776,P62280,P08865,P83881,Q07020,P61353,P46778,P56192,P05388,P18077,Q9Y3U8,P61247,P84098,Q15046,P30050,P35268,P18124,P62266,P62277,P62841,P32969,P61313,P62701,P61513,P62829,P62910,P23526,P41252,P18621,P36578,P62241,P39019,P46781,P62244,P63220,P15880,P39023,P49207,Q02543,P62753,P07814,P62249,P62424,P40429,P61927,P26373 47
Nonsense mediated decay nmd 0.5371083795384508 3.6240595756426366 0.0002900147561102 0.332388691432561 0.0807981110523117 85 Q9HAU5,P27635,P46776,P62280,P08865,P83881,Q07020,P61353,P46778,P05388,P18077,Q9Y3U8,P61247,P84098,P30050,P35268,P18124,P62266,P62277,P62841,P32969,P61313,P62701,P61513,P62829,P62910,Q9UPR3,P18621,P36578,P63151,P62241,P39019,P46781,P62244,P63220,P15880,P39023,P49207,Q02543,P62753,P62424,P62249,P40429,P61927,P26373 45
Cellular response to starvation 0.5251681614348322 3.477257025012948 0.0005065719549857 0.5063031065531324 0.1176091222158498 86 P27635,P46776,P62280,P08865,P83881,Q07020,P61353,P46778,Q92616,P05388,P18077,Q9Y3U8,P61247,P84098,P30050,P35268,P18124,P62266,P62277,P62841,P32969,P61313,P62701,P61513,P62829,P62910,P05198,Q9HB90,P18621,P36578,P42345,P62241,P38606,P39019,P46781,P62244,P63220,P21283,P15880,P39023,P49207,Q02543,P62753,P62424,P62249,P40429,P61927,P26373 48
Metabolism of water soluble vitamins and cofactors 0.6003147947336853 3.073803746026371 0.0021134841562249 0.9475134827672846 0.2171902898960495 34 P41440,Q96RQ3,Q13085,O00763,P05165,P50747 6
Eukaryotic translation initiation 0.4802193222091188 2.7672891529849166 0.005652459578652 0.9996278500863542 0.2429038996439914 100 P27635,P46776,P62280,Q7L2H7,P08865,Q07020,P83881,Q9NR50,P61353,P46778,Q13347,P05388,P18077,Q9Y3U8,P61247,P84098,P30050,P35268,P18124,Q9UI10,P62266,P62277,P62841,P32969,P61313,P62701,Q14152,P61513,P55884,P62829,P62910,P05198,P18621,P36578,P62241,P39019,P46781,P62244,P63220,P15880,P39023,P49207,Q02543,P62753,P62424,P62249,Q14232,P40429,P61927,P26373 50
Mitochondrial fatty acid beta oxidation 0.7476309699299978 2.761459588670178 0.0057543637388741 0.9996773623025692 0.2429038996439914 14 P11310,Q9Y305,Q9BV79,P05165,O00154 5
Metabolism of vitamins and cofactors 0.4963273128194921 2.7412949670976596 0.0061197541610544 0.9998066501572354 0.2435662156099683 45 P41440,Q96RQ3,Q13085,O00763,P05165,P50747,Q6NUM9,P11498 8
Biotin transport and metabolism 0.8670669102795863 2.6267307634036796 0.0086209515549164 0.999994219667783 0.2501762014734499 8 Q96RQ3,Q13085,O00763,P05165,P50747 5
Defects in vitamin and cofactor metabolism 0.7739800482200928 2.601562606061163 0.0092800125196172 0.9999977110394602 0.2501762014734499 11 P50747,Q96RQ3,P05165,Q13085 4
Regulation of cholesterol biosynthesis by srebp srebf 0.5887508687506362 2.5052091810446315 0.0122378992439031 0.9999999644584968 0.2501762014734499 23 Q9Y6B6,Q13085,P37268,O00763,Q16850 5
Formation of the cornified envelope 0.835228916417266 2.4865345337543507 0.0128994049379445 0.9999999860218624 0.2501762014734499 8 P04632,P14923,Q08554,P15924,Q14574 5
Keratinization 0.835228916417266 2.4865345337543507 0.0128994049379445 0.9999999860218624 0.2501762014734499 8 P04632,P14923,Q08554,P15924,Q14574 5
Branched chain amino acid catabolism 0.6800099204867537 2.4775876082349177 0.0132273930993043 0.9999999912016916 0.2501762014734499 15 Q96RQ3,P30084,P45954,P35610,Q9HCC0,Q6NVY1,O15382,P11182 8
Rhoa gtpase cycle 0.4638061673162391 2.4363936587648314 0.0148345305602273 0.9999999990915744 0.2542493182087439 46 P41440,P43121,Q8TAA9,P14923,Q07021,P42166,Q9NRG9,O15173,Q92974,P61586,Q92888 11
Defects in biotin btn metabolism 0.8505085091067874 2.4312566052867313 0.0150465539537001 0.999999999326906 0.2542493182087439 7 P50747,Q96RQ3,P05165,Q13085 4
Fatty acid metabolism 0.4562049817823892 2.4173099471197483 0.0156356967970823 0.9999999997075124 0.2587750797069348 51 O00767,P11310,Q9UJ83,P09110,Q9Y305,Q13085,Q9BV79,O75521,O00763,O43808,P05165,P34913,P51648,O60488,O00154,P42765,Q14914,P09960 18
Rhoc gtpase cycle 0.5222098481524261 2.399458174582647 0.0164193554850187 0.999999999903552 0.2587750797069348 33 P41440,P43121,P14923,Q07021,P42166,P61586,Q92888 7
Extension of telomeres 0.5314645956971408 2.347433366832192 0.0189032539524105 0.9999999999971516 0.2587750797069348 30 P41440 1
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.5827199368180541 2.334981511652079 0.0195443865922322 0.999999999998854 0.2587750797069348 21 P41440,Q9NRF9 2
Pcna dependent long patch base excision repair 0.6028471011952474 2.307615198606251 0.0210205484164685 0.9999999999998596 0.2623409821567133 18 P41440,Q9NRF9 2
Regulation of lipid metabolism by pparalpha 0.584304243429774 2.288865020799352 0.0220871961853055 0.9999999999999692 0.2652298701526018 20 P11310,P48163,P37268,Q9NVC6,P33121 5
Cytosolic trna aminoacylation 0.5531008675118265 2.254682055173437 0.0241532928191481 0.9999999999999984 0.2727354379257646 23 Q9P2J5,P47897,O43776,Q15181,Q9Y285,P26639,Q15046,P14868,P26640,P07814,Q9NSD9,P54136,P41252,P56192,P49588 15
Metabolism of steroids 0.4571607101331991 2.252701803796757 0.0242779571448634 0.9999999999999988 0.2727354379257646 43 Q15738,Q15800,Q14849,Q15392,P37268,P62826,Q86X55,P38435,O00767,Q15648,P49327,P22570,O00763,Q16850,P51659,Q96SU4,Q14534,Q13085,P15121,P53992,O95772,P22059,Q9Y6B6,Q15126,P22307,O95486,Q15436,P48449 28
Activation of gene expression by srebf srebp 0.6248358406821254 2.2455298742758005 0.02473413662301 0.9999999999999992 0.2734496215543889 16 Q16850,P37268,O00763,Q13085 4
Resolution of abasic sites ap sites 0.5333734986658426 2.2308576145756356 0.025690562112874 0.9999999999999998 0.2797559486067695 26 P41440,Q9NRF9 2
Recognition of dna damage by pcna containing replication complex 0.6040612464165034 2.212855896112967 0.0269075821808284 1.0 0.2861241372358323 17 P41440 1
Tbc rabgaps 0.6548381763315542 2.1769982799687986 0.0294806957753546 1.0 0.3014762752021845 13 P62330,P49815,Q15286,P51148,Q4KMP7 5
Dna damage bypass 0.541780012095801 2.1738948102728832 0.0297130358950512 1.0 0.3014762752021845 23 P41440 1
Termination of translesion dna synthesis 0.5816814919148894 2.1718592823484295 0.0298662785196708 1.0 0.3014762752021845 18 P41440 1
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.5529335770845363 2.1319657853085876 0.0330096593799345 1.0 0.3193226077517274 21 P41440 1
Dual incision in gg ner 0.5399645495397765 2.0991421038307747 0.0358043758539441 1.0 0.3352681354127808 22 P41440,Q86WJ1,P49005,Q9NRF9 4
Sphingolipid de novo biosynthesis 0.6969922823205128 2.0838761190208785 0.037171437114265 1.0 0.3368754739124651 10 Q96G23,P51648,Q06136 3
Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.8025862713133699 2.0830955524930945 0.0372425147038906 1.0 0.3368754739124651 6 P11310 1
Beta oxidation of decanoyl coa to octanoyl coa coa 0.8025862713133699 2.0830955524930945 0.0372425147038906 1.0 0.3368754739124651 6 P11310 1
Telomere maintenance 0.4593280246520084 2.049977663566775 0.0403666105406426 1.0 0.3418379849498197 38 P41440 1
Gap filling dna repair synthesis and ligation in gg ner 0.5615413967733043 2.0410717975909156 0.0412436911434346 1.0 0.344391362282726 18 P41440 1
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.904125847246344 2.0072777579654257 0.0447200960817413 1.0 0.3642987943968752 4 P61009 1
Incretin synthesis secretion and inactivation 0.904125847246344 2.0072777579654257 0.0447200960817413 1.0 0.3642987943968752 4 P61009 1
Trna aminoacylation 0.4743314024949666 2.002549070595865 0.0452257110728933 1.0 0.3662756716543045 33 Q9BW92,Q9H2U2,O43776,Q15181,Q9Y2Z4,P26639,Q15046,P26640,P07814,Q15031,P41252,P56192,P49588,Q6PI48,Q9NP81 15
Base excision repair 0.4878038654881969 1.9682907214911456 0.0490345969237386 1.0 0.3784630855089914 29 P41440,Q9NRF9 2
Peptide hormone metabolism 0.6151819936543433 1.954976815439876 0.0505858068405808 1.0 0.3784630855089914 13 P67812,O75787,Q8NEW0,P61009 4
Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.918691745603743 1.9460602197754404 0.0516475063298091 1.0 0.3784630855089914 3 P61586 1
Ion homeostasis 0.6927602901525896 1.9450395673718093 0.0517702163346296 1.0 0.3784630855089914 9 P16615,Q13555,P54709 3
Cardiac conduction 0.6927602901525896 1.9450395673718093 0.0517702163346296 1.0 0.3784630855089914 9 P16615,Q13555,P54709 3
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.9173421453998336 1.9408481245936744 0.0522767017743768 1.0 0.3784630855089914 3 P61009 1
Synthesis secretion and deacylation of ghrelin 0.9173421453998336 1.9408481245936744 0.0522767017743768 1.0 0.3784630855089914 3 P61009 1
Methylation 0.7690027322011871 1.937731894775686 0.0526559405615718 1.0 0.3784630855089914 6 P31153,Q9NZL9,P23526 3
Rhob gtpase cycle 0.5084252400558462 1.9326467049548648 0.0532797347134503 1.0 0.3784630855089914 23 P41440,P43121,Q8TAA9,P14923,Q92974,Q92888 6
Global genome nucleotide excision repair gg ner 0.4463043747530377 1.9324548237928991 0.0533033928868946 1.0 0.3784630855089914 38 P41440,Q9UNS2,O96019,Q86WJ1,Q9NRF9,P49005 6
Transcription coupled nucleotide excision repair tc ner 0.4286207114871381 1.930438980185196 0.0535524690168958 1.0 0.3784630855089914 42 P41440,Q9UNS2 2
Trna modification in the nucleus and cytosol 0.6373013908186564 1.900203717299053 0.0574063906522979 1.0 0.3883185215056468 11 Q9H974,Q9UBP6,Q9UET6,P07814,Q96PZ0,Q6YHU6,P57081 7
Biosynthesis of specialized proresolving mediators spms 0.9062191510365174 1.897808505446512 0.0577213123807827 1.0 0.3883185215056468 3 P34913,Q14914 2
Complex i biogenesis 0.4815051656598265 1.8615940464431813 0.0626603331168578 1.0 0.4041011297767728 27 O95169,Q9BU61,Q9P0J0,O95299,Q9H845,O75438,O95182,P19404,O75306,Q16795,P03915,P49821 12
Regulation of expression of slits and robos 0.4273887421084331 1.8471713463366668 0.06472231078116 1.0 0.4079599056854314 123 Q9HAU5,P27635,Q15008,P46776,P62280,P08865,P83881,Q07020,P61353,P25786,P46778,Q14997,P05388,P18077,Q9Y3U8,Q9UNM6,P61247,P84098,P35998,P30050,P35268,P18124,Q15370,P62266,P62277,P62841,P32969,Q15369,P61313,P62701,P61513,P62829,P62910,O00487,P18621,P36578,P62241,P39019,P46781,P62244,P63220,P15880,P39023,Q8TEY7,P60900,P25789,P49207,Q02543,P62753,P51665,P62249,P62424,P40429,P61927,P26373 55
Ras processing 0.7968005062296528 1.8467148416268109 0.0647884795306492 1.0 0.4079599056854314 5 O43924,P36404 2
Cargo trafficking to the periciliary membrane 0.5448904304071007 1.838743968795299 0.0659528530145514 1.0 0.4101443046842418 17 A6NIH7 1
Class i peroxisomal membrane protein import 0.6903961286871099 1.8197748639667928 0.0687932971057772 1.0 0.4170633817328991 8 P40855,P51648 2
Chrebp activates metabolic gene expression 0.7897593666394002 1.8172799411903324 0.0691742597581801 1.0 0.4170633817328991 5 O00763 1
Signaling by robo receptors 0.4386955287812258 1.8154117044215483 0.0694606637200521 1.0 0.4170633817328991 140 Q9HAU5,P27635,Q15008,P46776,P62280,P08865,P83881,Q07020,P61353,P25786,P46778,Q14997,P05388,P18077,Q9Y3U8,Q9UNM6,P61247,P84098,P35998,P30050,P35268,P18124,Q15370,P63000,O75122,P62266,P62277,P62841,P32969,Q15369,O14786,P61313,P62701,P35080,P61513,P62829,P17612,P62910,O00487,P16333,P18621,P36578,Q8N8S7,P62241,P39019,P46781,P62244,P63220,P15880,P39023,Q8TEY7,P60900,P25789,P49207,Q02543,P62753,P51665,P62249,P62424,Q01518,P40429,P61586,P61927,P26373 64
Carnitine metabolism 0.853336210789067 1.8082562959986963 0.0705666204602097 1.0 0.4218854176011683 4 O00763 1
Transport of bile salts and organic acids metal ions and amine compounds 0.8509247173005916 1.7987265269484771 0.0720619506106485 1.0 0.4262990603838798 4 P35613,Q8NEW0 2
Gluconeogenesis 0.5087689373737025 1.7759755873987284 0.0757369410063537 1.0 0.4323834377944704 20 P06744,P00558,P09972,P04406,P40926,P60174,P40925,P11498,P06733,Q02978,P04075,P09104 12
Ephb mediated forward signaling 0.5446801706436155 1.7536041229767405 0.0794983640707349 1.0 0.4470054281929705 16 O15511,Q92747,O15145,O15144,P61586,P07948 6
Maturation of sars cov 2 nucleoprotein 0.771829512065705 1.7420077296829406 0.0815070917164497 1.0 0.4470054281929705 5 Q99873,P78362,P48729 3
Chromosome maintenance 0.4019769766917067 1.7158174324487587 0.0861954625222161 1.0 0.4600393842660806 43 P41440 1
Crmps in sema3a signaling 0.7645237622645342 1.7112118901276157 0.0870420045260305 1.0 0.4619370671725984 5 Q9BPU6,O14786 2
Generation of second messenger molecules 0.8258075696974747 1.699076786353356 0.0893047166194813 1.0 0.4641845904885728 4 P16333 1
Inactivation of csf3 g csf signaling 0.7111508730336985 1.682680007274565 0.0924370540670547 1.0 0.4751469236730893 6 P40763,Q15370 2
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.3859969657509068 1.677792969339303 0.0933875223504883 1.0 0.4782677155670228 50 Q9UBQ5,P62280,P08865,Q7L2H7,Q13347,P23396,P61247,P62266,P62277,P62841,P62263,P62701,Q14152,P55884,P05198,P62241,P39019,P46781,P62244,P63220,P15880,P62753,P62249 23
Metabolism of porphyrins 0.6361687737518684 1.6648853132393322 0.0959356388678265 1.0 0.4803818020757372 9 Q7KZN9,P30043 2
Stimuli sensing channels 0.632709954377875 1.647556799571512 0.0994436515689465 1.0 0.4843531700543444 9 Q4KMQ2,Q96PU5,Q9C0H2 3
Cholesterol biosynthesis 0.5383565900049576 1.639546696292392 0.1010994538878633 1.0 0.4873063642415005 15 Q16850,P37268,Q15738,Q15392 4
Dual incision in tc ner 0.4354420691616141 1.637168772092471 0.1015952100576864 1.0 0.4880073365874388 32 P41440 1
Synthesis of leukotrienes lt and eoxins ex 0.9059210526315812 1.628582050534194 0.1034015266089234 1.0 0.4915983841850865 2 Q14914 1
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.6973553673986261 1.6210878188215925 0.1049988060338185 1.0 0.4958079213732514 6 O95864,P51659,P09110,P33121 4
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.5211584033351905 1.605674712623681 0.1083454001915162 1.0 0.5064602096200744 16 P48643,Q13885,Q9BUF5,Q9BVA1,P49368,P04350,P17987,Q9UHV9,P40227,P61758 10
Signal transduction by l1 0.5801696212540585 1.592287144148434 0.1113202002174178 1.0 0.5134736387512022 11 P00533,O14786,P63000,P27361 4
Formation of xylulose 5 phosphate 0.826916748930568 1.5871513248690967 0.1124783759029131 1.0 0.5171035565437556 3 P14550,Q7Z4W1 2
Rhod gtpase cycle 0.4456344285415931 1.580197101504411 0.1140617353667521 1.0 0.5198170740045057 27 P43121,Q8TAA9,Q68EM7,P42166,O15173,Q5JTV8 6
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.5987639641892654 1.5796453784643771 0.1141881009658138 1.0 0.5198170740045057 10 Q10567,P04439,Q96CW1,O94973 4
Nucleotide excision repair 0.3758973107388805 1.5715648906973547 0.1160514942063914 1.0 0.5205521740764816 50 P41440,Q9UNS2 2
Glucose metabolism 0.3651600708659758 1.570847664855759 0.1162180374284176 1.0 0.5205521740764816 60 P04406,P60174,P04075,P08237,P78406,Q01813,P09972,A6NDG6,P17858,Q02978,Q9BRR6,P52789,P06744,P17612,P40926,P19367,P40925,P11498,Q9NRG9,Q7Z3B4 20
Interconversion of nucleotide di and triphosphates 0.48972859927128 1.5636900434776748 0.1178903770909709 1.0 0.5254066881104843 18 Q9H773,P15531,P00568,P27144,P22392 5
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.720335614221854 1.5235909827069225 0.1276109171262218 1.0 0.5586670573765496 5 Q99808 1
Rab regulation of trafficking 0.4164061349566155 1.5092063593143346 0.1312460555895414 1.0 0.5621864112027566 33 Q4KMP7,P61020,P62330,P49815,P51153,P51148,P31150,P50395,P61026,Q15286,Q14964 11
Respiratory electron transport 0.3691579890044347 1.5080462769551677 0.1315426834374888 1.0 0.5621864112027566 51 O95169,Q9BU61,Q9P0J0,O95299,P51970,Q9H845,O75438,Q9BSH4,O95182,P19404,P31930,Q16795,P03915,P49821,O75306 15
Gap junction degradation 0.6718075218036199 1.5063765545335146 0.1319705358674094 1.0 0.5621864112027566 6 Q96CW1 1
Pregnenolone biosynthesis 0.7768268597761645 1.5029897816088482 0.1328416790400997 1.0 0.564172130801399 4 Q14849,P15121,O95772 3
Glycolysis 0.3679094425660791 1.4810627185619063 0.1385898612873881 1.0 0.5719086921359006 49 P08237,P78406,P52789,Q01813,P06744,P09972,P17612,A6NDG6,P60174,Q9NRG9,P19367,P17858,Q7Z3B4,Q9BRR6,P04075 15
Beta oxidation of very long chain fatty acids 0.7702435813034623 1.4764956362643022 0.1398108858419176 1.0 0.5731202294171153 4 O75521,P51659,P09110 3
Nef mediated downregulation of mhc class i complex cell surface expression 0.7701742651789257 1.4762165415739477 0.1398857702812772 1.0 0.5731202294171153 4 Q10567,P04439 2
Pyruvate metabolism 0.5184901870369896 1.453716580681399 0.1460248993148107 1.0 0.5817276569192861 14 P08559,Q8NCN5,P48163,P35613,Q04760 5
Nuclear receptor transcription pathway 0.8618421052631582 1.44727038383574 0.1478212104778273 1.0 0.5849856426011748 2 Q9UHY1 1
Synthesis of very long chain fatty acyl coas 0.6287376960208104 1.4268511050691095 0.1536228169187488 1.0 0.5992999951421706 7 Q9NZ01,O60488 2
Basigin interactions 0.6973186433818065 1.4251201776486868 0.1541224649318442 1.0 0.5992999951421706 5 P08195,P35613,P54709 3
Linoleic acid la metabolism 0.8552631578947374 1.4201924941215909 0.1555516482331462 1.0 0.5992999951421706 2 P33121 1
Vldlr internalisation and degradation 0.60664878472182 1.4152050020514133 0.1570083983629653 1.0 0.5992999951421706 8 Q96CW1 1
Cell cell communication 0.4243050563841956 1.411666865164678 0.1580480741112233 1.0 0.5992999951421706 27 Q96J84,Q9Y624,P14923,Q13418 4
Zinc transporters 0.8523026315789493 1.4080093928294162 0.1591282886980494 1.0 0.5992999951421706 2 Q8NEW0 1
Metal ion slc transporters 0.8523026315789493 1.4080093928294162 0.1591282886980494 1.0 0.5992999951421706 2 Q8NEW0 1
Trafficking of ampa receptors 0.5852046722705714 1.4076934688730147 0.1592218565971275 1.0 0.5992999951421706 9 Q13555,Q96CW1,Q9UM54 3
Fcgr3a mediated il10 synthesis 0.6931153369711331 1.4070984313516977 0.1593982032093954 1.0 0.5992999951421706 5 P07948 1
Downregulation of tgf beta receptor signaling 0.624510355783208 1.406937249722637 0.1594459967695947 1.0 0.5992999951421706 7 Q9Y5K5,Q96PU5,P62136,Q9Y3F4,Q9UNE7 5
The role of nef in hiv 1 replication and disease pathogenesis 0.5336099582240286 1.406375803071561 0.1596125615202765 1.0 0.5992999951421706 12 Q10567,P04439,Q96CW1,O94973 4
Phase ii conjugation of compounds 0.4244734483491946 1.3934538678183357 0.1634825859745226 1.0 0.6089582163362214 26 Q96IU4,Q99707,Q9NZL9,Q8WUX2,P21266,P23526,P14550,O95861,P31153 9
Formation of tubulin folding intermediates by cct tric 0.5157087561799077 1.3803494327662205 0.1674790816173219 1.0 0.6155629569734287 13 P48643,Q13885,Q9BUF5,Q9BVA1,P49368,P04350,P17987,P40227 8
Hdms demethylate histones 0.6427922868984992 1.3752912019998835 0.1690411830122518 1.0 0.6164250469530543 6 Q9Y2K7 1
Gap junction trafficking and regulation 0.5273526221933573 1.3708674793328322 0.1704162707046146 1.0 0.6197786038210417 12 Q9BVA1,Q96CW1,Q9UM54,P04350 4
Pentose phosphate pathway 0.6415082289451559 1.3694755565828534 0.1708506704000574 1.0 0.6197786038210417 6 Q96G03,P52209,P37837 3
Signaling by pdgf 0.6375486414948937 1.3515364107481278 0.1765236644814072 1.0 0.6321271584128542 6 P40763 1
Downstream signal transduction 0.6375486414948937 1.3515364107481278 0.1765236644814072 1.0 0.6321271584128542 6 P40763 1
Cell junction organization 0.4801919884072879 1.3456938419649171 0.1784012731692466 1.0 0.6355830524929935 16 P21333,Q14315,Q9Y624,P14923,Q13418,P19022,Q92692 7
Rho gtpases activate wasps and waves 0.4463981090054348 1.339918713321247 0.1802717734893115 1.0 0.6395473282827334 20 O15511,P61160,Q92747,Q9UQB8,O15145,Q7L576,P16333,O15144,P63000,Q9Y2A7 10
Cell cell junction organization 0.5890850460300325 1.3292563992177089 0.1837633936320994 1.0 0.6464202205290771 8 P14923 1
Hdr through homologous recombination hrr 0.4256137541207442 1.318690263286297 0.1872726832270621 1.0 0.6506919719725686 23 P41440 1
Tysnd1 cleaves peroxisomal proteins 0.6697398748765082 1.306733785965296 0.1913031399170619 1.0 0.659617014615018 5 P51659,Q15067,P09110,O00116 4
Stat3 nuclear events downstream of alk signaling 0.7244288212556034 1.291634497243338 0.1964837514354731 1.0 0.666198365933959 4 P40763,Q13547 2
Signaling by alk 0.7244288212556034 1.291634497243338 0.1964837514354731 1.0 0.666198365933959 4 Q13547,P40763 2
Serine biosynthesis 0.7243746229943477 1.291415600178239 0.19655960401928 1.0 0.666198365933959 4 Q9NRX5 1
Gap junction assembly 0.6631065155577446 1.2782280334536478 0.2011690343800327 1.0 0.6689169446470571 5 Q9BVA1,P04350 2
Transport of connexons to the plasma membrane 0.6631065155577446 1.2782280334536478 0.2011690343800327 1.0 0.6689169446470571 5 Q9BVA1,P04350 2
Erbb2 regulates cell motility 0.7466863665188895 1.26865187302012 0.2045652545116523 1.0 0.6720740555064426 3 P61586 1
Polb dependent long patch base excision repair 0.6188993494943512 1.266961460769468 0.2051690705388595 1.0 0.6724718006132504 6 Q86W56,P27695 2
Signaling by retinoic acid 0.5551369830197863 1.2546822115568286 0.2095941457821712 1.0 0.680614330717491 9 P08559,Q01469 2
Sulfur amino acid metabolism 0.5352313004938594 1.244473245675923 0.2133254401078477 1.0 0.6827779007378267 10 Q9BV20,Q99707,Q13126,P23526,P25325 5
Signaling by vegf 0.3950839820143682 1.2434418094686912 0.2137050715877189 1.0 0.6827779007378267 30 Q05655,O14786,O75116,P04792,Q9UQB8,P17612,P14923,P16333,P42345,P61586 10
Heme degradation 0.7118963354042629 1.2410283257092631 0.2145952850895272 1.0 0.6840531627682183 4 P30043,P09601 2
Carboxyterminal post translational modifications of tubulin 0.6101115921159627 1.2270881766092034 0.219789451224541 1.0 0.6990107432780496 6 Q9BVA1,P04350 2
Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0.7075519371684561 1.22349409516681 0.2211431330822333 1.0 0.7017138596436241 4 Q13547,P04179 2
Signaling by csf3 g csf 0.5666749872138142 1.219397250572829 0.2226934529743953 1.0 0.7050272272575744 8 P40763,Q15370 2
Aquaporin mediated transport 0.7057809182764805 1.2163480304136862 0.2238523721466596 1.0 0.7070892390029409 4 Q99797 1
Fructose metabolism 0.8049342105263182 1.2136118987722275 0.224895961165541 1.0 0.7087052716358568 2 Q00796 1
Gpcr ligand binding 0.5456538359589378 1.2063684539549953 0.2276754539103669 1.0 0.7143060975160836 9 Q9NRV9,P04083 2
Glyoxylate metabolism and glycine degradation 0.527354458479272 1.2027487679064737 0.2290735557182488 1.0 0.7147712974988469 10 P11182 1
Growth hormone receptor signaling 0.6047430830039497 1.2027325454989866 0.2290798353388727 1.0 0.7147712974988469 6 P40763,P27361,P28482,P07948,P18031 5
Metabolism of steroid hormones 0.6023972088238594 1.192091935138606 0.2332251989357945 1.0 0.720360758575525 6 Q14849,P15121,O95772 3
Gpvi mediated activation cascade 0.6425846935878747 1.1900592140228987 0.2340231193275537 1.0 0.7212261177506246 5 P61586,P07948 2
Cd209 dc sign signaling 0.6982733870914495 1.186070188852708 0.2355945821751082 1.0 0.7214718351007656 4 P07948 1
Activation of ampk downstream of nmdars 0.5998320600885702 1.1804587322844295 0.2378178144222282 1.0 0.7252667120730019 6 Q9BVA1,P04350 2
Purine ribonucleoside monophosphate biosynthesis 0.5216322742451188 1.1724480475637298 0.2410172186879955 1.0 0.7298630122442995 10 P31939,P12268,P49915,O15067,P22234 5
Signaling by tgf beta receptor complex 0.4221601319785936 1.1699413999539552 0.2420245518962032 1.0 0.7313236459683536 20 Q9Y5K5,Q96PU5,P22681,P62136,Q9Y624,Q9Y3F4,P61586,P27361,Q13547,Q93008,P50750,Q9UNE7 12
G alpha i signalling events 0.4101430401533312 1.1602543522094206 0.2459452637147976 1.0 0.7356418846674303 22 Q05655,Q9NRV9,P17612,P08754,Q13555,Q00535,P04083 7
Peroxisomal lipid metabolism 0.5183918442773192 1.1552962713910155 0.2479691223279854 1.0 0.736505303630882 10 P51648,O75521,Q9UJ83,P09110 4
The citric acid tca cycle and respiratory electron transport 0.335410728100978 1.1488388111204058 0.2506224524467575 1.0 0.7380910703136009 90 O95169,Q9P0J0,O95299,P35613,O75438,P19404,P31930,Q16795,P51970,Q8NCN5,P00338,P03915,P49821,P08559,P08574,P48163,Q04760,P40926,O95182,O75306,Q9BU61,P50213,Q9H845,P07954,Q9BSH4,Q6P587 26
Eph ephrin signaling 0.376077511718747 1.1366260706442453 0.2556946366818087 1.0 0.7426799572753832 32 O15511,O94973,Q92747,Q15375,O15145,O15144,P07948,P61586,Q96CW1 9
Biological oxidations 0.3495623825103245 1.1327021865211964 0.2573393391548055 1.0 0.7432036363458701 41 Q96IU4,Q99707,Q15185,P05091,Q9NZL9,Q8WUX2,P21266,P10768,P23526,Q16850,P14550,O95861,P07099,P11766,Q86WA6,O43488,P31153 17
Methionine salvage pathway 0.6844956153405858 1.130591063588807 0.2582272505322334 1.0 0.7432036363458701 4 Q9BV20,Q13126 2
Anti inflammatory response favouring leishmania parasite infection 0.5111647915692581 1.1170713331319908 0.2639638264530322 1.0 0.7464242937697719 10 P07948,P08754 2
Plasma lipoprotein assembly 0.6809944153452268 1.116516026755776 0.2642013138553987 1.0 0.7464242937697719 4 Q9Y6B6 1
Cell surface interactions at the vascular wall 0.4437453140601385 1.1140901674735453 0.2652405064006009 1.0 0.7464242937697719 16 P35613,Q9Y624,P14174,Q9UNN8,P54709 5
Neuronal system 0.3319867213423422 1.108688607794877 0.2675645381235521 1.0 0.7510308905186748 49 P41440,Q9UM54,Q9BVA1,O94925,P17612,P08754,Q13555,P51649,Q96CW1 9
Pyruvate metabolism and citric acid tca cycle 0.3718938032571068 1.101767544222452 0.2705627437726432 1.0 0.753833528732468 32 P08559,P50213,Q8NCN5,P35613,P48163,P07954,Q04760,P40926,Q6P587 9
Semaphorin interactions 0.4117889387555143 1.0975989316204773 0.2723796595906163 1.0 0.757335061496464 20 Q9BPU6,P61586,O14786 3
Rna polymerase ii transcribes snrna genes 0.3955335827262122 1.0951677091016263 0.2734431695598034 1.0 0.7587775601530004 23 Q9H0H0,P29083 2
Tgf beta receptor signaling activates smads 0.5059192439235976 1.089359556612406 0.2759953588322976 1.0 0.7628205056614893 10 Q9Y5K5,Q96PU5,P62136,Q9Y3F4,P22681,Q9UNE7 6
Activated ntrk2 signals through cdk5 0.7717105263157948 1.0785873240337234 0.2807717345915419 1.0 0.7718470562878512 2 Q00535 1
Epha mediated growth cone collapse 0.5369519164468491 1.0738834646371982 0.2828749152564742 1.0 0.7722792640757847 8 Q15375,P61586,P07948 3
Synthesis of bile acids and bile salts 0.6695194206714806 1.0704712935741991 0.2844072235971842 1.0 0.7722792640757847 4 Q96SU4,P51659,P22059 3
Bile acid and bile salt metabolism 0.6695194206714806 1.0704712935741991 0.2844072235971842 1.0 0.7722792640757847 4 Q96SU4,P51659,P22059 3
P75ntr negatively regulates cell cycle via sc1 0.7677631578947406 1.0626648393177045 0.2879339713747009 1.0 0.7773101203972062 2 Q13547 1
Influenza infection 0.3617191821588021 1.0411736838795342 0.2977949469490777 1.0 0.7903999661953051 124 P27635,P46776,P62280,P62826,P08865,P83881,Q07020,P61353,P46778,P05388,P18077,Q9Y3U8,P78406,P61247,P84098,P62487,P30050,P35268,P18124,P62266,P62277,P62841,Q13217,P32969,P61313,P62701,P61513,P62829,P62910,P18621,P36578,P62241,O95639,P39019,P46781,P62244,P63220,P15880,P39023,P49207,Q02543,P62753,P62424,P62249,Q9NRG9,P40429,Q7Z3B4,P61927,P26373 49
Tryptophan catabolism 0.7608552631579011 1.0348767439310549 0.3007264767290105 1.0 0.7903999661953051 2 Q6YP21 1
Detoxification of reactive oxygen species 0.4769112412925554 1.024451364883385 0.3056221314206211 1.0 0.8002474230618896 11 P07237,P04179,Q96HE7,P30041,Q8TED1,P30044 6
Cyclin a b1 b2 associated events during g2 m transition 0.4759852472189305 1.0193783908020213 0.3080233610111076 1.0 0.805021654574996 11 Q9Y570 1
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.3155014111766607 1.016519379472427 0.3093821237969729 1.0 0.8064614165080115 60 O95169,Q9BU61,Q9P0J0,O95299,P51970,Q9H845,O75438,Q9BSH4,O95182,P19404,P31930,Q16795,P03915,P49821,O75306 15
Rho gtpases activate nadph oxidases 0.5982877839973568 1.0006689385631948 0.3169868890420857 1.0 0.8104657461029517 5 P63000,P28482,Q05655,P27361 4
Transport of vitamins nucleosides and related molecules 0.5216318711757768 0.9992574522073052 0.3176699909348253 1.0 0.8104657461029517 8 Q99808 1
Repression of wnt target genes 0.6764398851753646 0.9913501818110344 0.3215146172785201 1.0 0.8174291510487641 3 Q13363 1
Regulation of bach1 activity 0.7486842105263205 0.9861794929738316 0.3240450405447368 1.0 0.8174291510487641 2 P63208 1
Fbxw7 mutants and notch1 in cancer 0.7486842105263205 0.9861794929738316 0.3240450405447368 1.0 0.8174291510487641 2 P63208 1
Translation 0.4016610907279314 0.9848474520412792 0.3246990081544214 1.0 0.8174291510487641 207 Q07020,P56192,P61009,Q9Y3U8,Q9H2U2,Q9BYD3,P84098,O43776,P61313,Q9Y2Z4,P55884,P05198,P41252,P39023,P26639,P62753,P62249,Q9H2W6,Q9NP92,P61927,P46776,Q7L2H7,P08865,P83881,P18077,P61247,O76094,P30050,P35268,P18124,Q5T653,Q7Z2W9,P61513,P51398,P67812,P09001,P39019,P46781,Q02543,P26640,P07814,Q9BRJ2,P40429,P26373,P62280,Q9NR50,P61353,P46778,P61619,Q9BW92,Q15046,Q15031,Q9UI10,P62266,P62277,P62841,Q13084,P49588,P62701,Q14152,Q05639,P62910,Q9NSD9,P60468,P18621,P36578,Q9NP81,P13639,P62244,P15880,P49207,Q7Z7H8,O75616,P27635,Q15181,Q9UHB9,Q13347,P05388,P32969,P62829,P62241,Q9H9J2,Q9UNL2,P63220,P62424,P82675,Q14232,Q6PI48 88
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.6726576726396827 0.976603974122648 0.3287652508785816 1.0 0.8178035615604718 3 O14786 1
Recycling of eif2 gdp 0.5309317160938022 0.9659041065727388 0.3340921672801162 1.0 0.8229262518989305 7 Q9UI10,Q14232,Q9NR50 3
Nephrin family interactions 0.513368758077593 0.9591909365597742 0.3374625655361998 1.0 0.8265969349733782 8 Q96J84 1
Vitamin b5 pantothenate metabolism 0.6679274100460494 0.9582020763223827 0.3379608704432733 1.0 0.8265969349733782 3 Q9NVE7 1
Rab geranylgeranylation 0.3997900214996601 0.9576600481687468 0.338234208854864 1.0 0.8265969349733782 18 P51153,P51148,P61026,Q15286,Q14964 5
Metabolism of amino acids and derivatives 0.392271676483333 0.9436127926772312 0.3453675525912638 1.0 0.8284980824817574 186 Q15008,Q07020,P56192,Q9Y3U8,P30084,P84098,P35998,Q9NRX5,P35610,Q99707,P61313,P23526,P41252,P11182,Q96RQ3,Q13126,P39023,P62753,P62249,O15382,P61927,P46776,P08865,P83881,P25786,Q9HCC0,P25325,P18077,P61247,P30050,P35268,P18124,P61513,Q02218,Q6YP21,O00487,P08195,P31937,P39019,P46781,P19623,Q02543,Q92947,P07814,P40429,P26373,O43175,P62280,P61353,P46778,Q6NVY1,Q9UNM6,Q9Y617,Q15046,P62266,P62277,P62841,P08559,P62701,P62910,P18621,P36578,P12532,P62244,P61457,P15880,P60900,P49207,P27635,Q14997,P05388,P32969,P62829,P62241,P63220,O94925,P25789,P45954,P51665,P62424 80
Snrnp assembly 0.3314240532414669 0.9372405888534102 0.3486348156533749 1.0 0.8284980824817574 40 P78406,P62316,P62314,Q9BQA1,Q16637,Q8TEQ6 6
Post chaperonin tubulin folding pathway 0.4760178401014358 0.932325195675833 0.3511684904516383 1.0 0.8284980824817574 10 Q9BVA1,P04350,P36404 3
Rmts methylate histone arginines 0.3873740066085396 0.92925666496438 0.3527560874771724 1.0 0.8284980824817574 20 O96019,P15880,O14744,Q9BQA1,Q12824,Q96GM5,Q99873,P61964 8
G alpha z signalling events 0.6337624805693501 0.928213649506778 0.3532967554815549 1.0 0.8284980824817574 4 P08754 1
G protein mediated events 0.4583891149654397 0.9234069582911192 0.3557951669089578 1.0 0.8284980824817574 11 Q13555,Q05655,P08754 3
G alpha 12 13 signalling events 0.5422999903273784 0.9212461759152872 0.3569219151677627 1.0 0.8284980824817574 6 Q92974,P61586,Q92888 3
Peptide ligand binding receptors 0.5212916857917375 0.9210249183484586 0.3570374175069672 1.0 0.8284980824817574 7 P04083 1
Class a 1 rhodopsin like receptors 0.5212916857917375 0.9210249183484586 0.3570374175069672 1.0 0.8284980824817574 7 P04083 1
Mitochondrial trna aminoacylation 0.4289014789621653 0.917243532873072 0.3590150396060281 1.0 0.8284980824817574 14 Q9BW92,Q9H2U2,Q9Y2Z4,P26640,Q15031,Q6PI48,Q9NP81 7
Defective intrinsic pathway for apoptosis 0.4277862023040826 0.9106885739050928 0.362459486150108 1.0 0.8284980824817574 14 P20810,Q07021,Q00535,P04632 4
Circadian clock 0.4714461108112401 0.90852046339042 0.3636033072288835 1.0 0.8284980824817574 10 Q15648,P63208,P62136,Q86X55,Q13616 5
Parasite infection 0.3631271865737627 0.9082799881270028 0.363730312728717 1.0 0.8284980824817574 25 O15511,P61160,Q92747,Q9UQB8,O15145,Q7L576,O00159,P16333,O15144,P63000,P07948,Q9Y2A7 12
Formyl peptide receptors bind formyl peptides and many other ligands 0.6533735304861459 0.9019008431536416 0.3671095434360074 1.0 0.8284980824817574 3 P04083 1
Sema4d mediated inhibition of cell attachment and migration 0.6514139090296301 0.8943604308942313 0.3711290764311676 1.0 0.8284980824817574 3 P61586 1
Nucleotide biosynthesis 0.4321403364498108 0.8930797644816167 0.3718144586616769 1.0 0.8287000654651455 13 P31939,P12268,P49915,P11172,O15067,P22234 6
Prolactin receptor signaling 0.6482918957736378 0.8823688130595775 0.3775773951004879 1.0 0.8356175005738368 3 P63208 1
Opioid signalling 0.397390963463312 0.8797897991658984 0.3789731917506396 1.0 0.8356175005738368 17 Q05655,P17612,P08754,Q13555,Q00535 5
Integrin cell surface interactions 0.564880439421898 0.859967826703042 0.3898067778443979 1.0 0.8356175005738368 5 Q9Y624 1
Translation of sars cov 2 structural proteins 0.3804504403993631 0.8310676723170766 0.4059354010141249 1.0 0.8465090024141857 18 Q9H0U3,P78362,P48729,Q96SB4,Q99873 5
Activation of rac1 0.5569872474939892 0.8271691025580543 0.4081412215320179 1.0 0.8480277497260319 5 P16333 1
Smad2 smad3 smad4 heterotrimer regulates transcription 0.6053324555628711 0.8171436106184574 0.4138463630909677 1.0 0.8529059932394952 4 Q13547,P50750,P27361 3
Synthesis of pips at the er membrane 0.70427631578948 0.8122329087717105 0.4166579996048938 1.0 0.8529059932394952 2 Q13614 1
Glycogen synthesis 0.6024479812732604 0.8060118521574645 0.4202360151983124 1.0 0.8529059932394952 4 Q96G03,P13807 2
Adherens junctions interactions 0.4949412470362344 0.7997984871301009 0.4238275597297789 1.0 0.8529059932394952 7 P19022,P14923 2
Gdp fucose biosynthesis 0.7000000000000066 0.7958704850328171 0.426107317974953 1.0 0.8529059932394952 2 Q13630 1
Rac3 gtpase cycle 0.3338166003300327 0.7929115645393999 0.4278293490750298 1.0 0.8529059932394952 32 P43121,Q8TAA9,P49257,Q9UQB8,Q68EM7,P42166,O15173,Q9Y2A7 8
Antigen activates b cell receptor bcr leading to generation of second messengers 0.5983766678309774 0.7903496870186347 0.4293235766747996 1.0 0.8529059932394952 4 P16333 1
Platelet adhesion to exposed collagen 0.6983552631579011 0.7895987340187032 0.4297621478344591 1.0 0.8529059932394952 2 P07948 1
Reduction of cytosolic ca levels 0.6235639227795087 0.7884512274575993 0.4304328164015543 1.0 0.8529059932394952 3 P16615 1
Platelet calcium homeostasis 0.6235639227795087 0.7884512274575993 0.4304328164015543 1.0 0.8529059932394952 3 P16615 1
Adora2b mediated anti inflammatory cytokines production 0.4912907617720636 0.7832149820183683 0.4335008784216123 1.0 0.8537037445834251 7 P08754 1
Interleukin 12 family signaling 0.3370664038727439 0.7813137471842457 0.4346179866513382 1.0 0.8537037445834251 30 Q99439,Q00169,P40763,Q13126,P38646,P07237,P14174,P37837,Q9H3K6,P04179,P11233,P60953,Q9UL46,P27824,P05388 15
Homology directed repair 0.3158304923837939 0.7773302691237896 0.4369639410538277 1.0 0.8537037445834251 39 P41440 1
Plasma lipoprotein assembly remodeling and clearance 0.3644691173733932 0.7755195071941821 0.4380327431680269 1.0 0.8545932930435034 20 Q96CW1,P98155,P35610 3
Regulation of mecp2 expression and activity 0.4436988791393893 0.7658988828358698 0.4437364707030646 1.0 0.862098889385452 10 Q92769,P51608,P42858,P17612,Q13555,Q13547 6
Ion channel transport 0.3400368626210531 0.749863606413185 0.453336855384209 1.0 0.8734415484788425 26 P16615,Q96PU5,P21283,Q4KMQ2,Q13555,P54709,Q9C0H2 7
Transcriptional regulation by mecp2 0.3990089935049093 0.7442819207621867 0.4567059364804762 1.0 0.875166308321484 14 Q92769,P51608,P42858,P17612,Q13555,Q13547,P18031 7
Tnfr1 induced nfkappab signaling pathway 0.4979551518443588 0.7269195107169787 0.4672752642933313 1.0 0.8904438346930376 6 O14920,P63244 2
Folding of actin by cct tric 0.4633701997596549 0.7215924557366783 0.4705450788392193 1.0 0.8908149564274216 8 P48643,P49368,P17987,P40227 4
Netrin 1 signaling 0.4485303091445949 0.7202040133589711 0.4713993932450135 1.0 0.8908149564274216 9 P16333 1
Runx2 regulates osteoblast differentiation 0.6051332675222091 0.7199235773584052 0.4715720504661131 1.0 0.8908149564274216 3 Q13951,P27361 2
Antigen presentation folding assembly and peptide loading of class i mhc 0.3874782196091729 0.7195377838243782 0.4718096305729373 1.0 0.8908149564274216 15 Q9Y6B6,O94979,Q9NZ08,P04439,P53992,Q15436,P27824,P10321 8
Small interfering rna sirna biogenesis 0.5787692599571441 0.71582956646219 0.4740965935043209 1.0 0.8930506011651114 4 Q9UPY3 1
Signaling by kit in disease 0.5729029625237564 0.6938610259498604 0.4877693672282255 1.0 0.906415724401309 4 P40763 1
Muscle contraction 0.3391266667174455 0.6926247639380764 0.4885450652969543 1.0 0.906415724401309 23 P16615,P04083,P54709 3
Rhou gtpase cycle 0.3827039448861187 0.6921130348088126 0.4888663464917457 1.0 0.906415724401309 15 P16333,Q8TAA9,Q9UM54 3
Mecp2 regulates transcription of neuronal ligands 0.5958576059043847 0.6860089173164229 0.4927074851945925 1.0 0.906415724401309 3 Q13547 1
Nicotinate metabolism 0.5954390153486087 0.6844883687620246 0.4936668315613912 1.0 0.906415724401309 3 P43490 1
Beta oxidation of pristanoyl coa 0.6690789473684287 0.6802007624465893 0.4963773496512593 1.0 0.9066679409571726 2 P51659 1
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.6690789473684287 0.6802007624465893 0.4963773496512593 1.0 0.9066679409571726 2 P51659 1
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.4249562716300676 0.6720361940045191 0.501560654796156 1.0 0.9066679409571726 10 P48643,P49368,P17987,P40227 4
Triglyceride metabolism 0.4840332110205861 0.6677287794812691 0.5043067357668489 1.0 0.9066679409571726 6 Q01469,P17612 2
Triglyceride catabolism 0.4840332110205861 0.6677287794812691 0.5043067357668489 1.0 0.9066679409571726 6 Q01469,P17612 2
Plasma lipoprotein remodeling 0.5896676538335002 0.6636157213034886 0.5069362925707135 1.0 0.9066679409571726 3 P07237,Q9BU23 2
Ca2 pathway 0.5892573785960118 0.6621386001038843 0.50788239975799 1.0 0.9066679409571726 3 Q08209 1
Rrna processing in the mitochondrion 0.5638401844731187 0.6602567320261655 0.5090890912728132 1.0 0.9066679409571726 4 Q9BQ52,Q99714 2
Trna processing in the mitochondrion 0.5638401844731187 0.6602567320261655 0.5090890912728132 1.0 0.9066679409571726 4 Q9BQ52,Q99714 2
Bbsome mediated cargo targeting to cilium 0.4636177490418867 0.65974612886059 0.5094167591093033 1.0 0.9066679409571726 7 P48643,P49368,P17987,Q9NQ48 4
Leishmania infection 0.3058787724905813 0.6591084672820275 0.5098261187793793 1.0 0.9066679409571726 37 O15511,Q92747,Q9UQB8,P17612,O15145,P08754,O00159,P16333,O15144,P07948,P09601,Q9Y2A7 12
Heme signaling 0.4624600655197076 0.6546813320161549 0.5126729469061782 1.0 0.9087278666372788 7 P09601,Q15648 2
Processing and activation of sumo 0.6598684210526395 0.6467740778521253 0.5177781715692684 1.0 0.9087278666372788 2 Q9UBE0 1
Sumo is conjugated to e1 uba2 sae1 0.6598684210526395 0.6467740778521253 0.5177781715692684 1.0 0.9087278666372788 2 Q9UBE0 1
Sumo is transferred from e1 to e2 ube2i ubc9 0.6598684210526395 0.6467740778521253 0.5177781715692684 1.0 0.9087278666372788 2 Q9UBE0 1
Hsf1 dependent transactivation 0.3806121470428106 0.6416289574079672 0.5211141265298673 1.0 0.9087278666372788 14 P54652,Q96B36,P04792,Q13555,P42345 5
Integration of energy metabolism 0.3398888284922131 0.6414324949402367 0.521241726382915 1.0 0.9087278666372788 21 P17612,O00763,O60488,Q13085 4
Mecp2 regulates neuronal receptors and channels 0.4583814489530677 0.6369116011203607 0.5241824256888552 1.0 0.9087278666372788 7 Q92769,P51608,Q13547 3
Ra biosynthesis pathway 0.5814231346118568 0.6341105187191195 0.5260086985702688 1.0 0.9087278666372788 3 Q8NBN7 1
Glutamate and glutamine metabolism 0.457380223730655 0.6325675401330489 0.5270160898721035 1.0 0.9087278666372788 7 P04181,O94925,P32322,P54886,P00367 5
Glutamate neurotransmitter release cycle 0.5797959855215575 0.6283328317386362 0.5297859281866706 1.0 0.9087278666372788 3 O94925,O75915 2
Darpp 32 events 0.4289688502490204 0.627293254409214 0.5304670243512775 1.0 0.9087278666372788 9 Q08209,P17612,Q00535 3
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.3236256476264194 0.6264567105645308 0.5310154224283883 1.0 0.9087278666372788 25 Q99439,Q00169,Q13126,P14174,P37837,P04179,P05388 7
Rhoq gtpase cycle 0.3413439796816947 0.606053092589403 0.5444794980541905 1.0 0.9175318404634064 19 Q68EM7 1
Rab gefs exchange gtp for gdp on rabs 0.3205358228322124 0.6056607932540256 0.5447400240074063 1.0 0.9175318404634064 25 P61020,P51153,P51148,P31150,P50395,P61026,Q7Z392,Q15286,Q14964 9
Response of eif2ak1 hri to heme deficiency 0.5728858177032046 0.6039719745238501 0.545862274964134 1.0 0.9175318404634064 3 P05198,P08243 2
Apoptosis induced dna fragmentation 0.4045677214175812 0.5731389683294619 0.5665506041079378 1.0 0.939079753995456 10 P10412 1
Dcc mediated attractive signaling 0.5393000765378104 0.5715942384339479 0.5675968996663203 1.0 0.939079753995456 4 P16333,P63000 2
Cell extracellular matrix interactions 0.4425388434825607 0.569081188335276 0.5693010439704098 1.0 0.939079753995456 7 Q14315,P21333,Q13418 3
Signaling by wnt in cancer 0.4292664096155171 0.567574243556982 0.5703241004164794 1.0 0.939079753995456 8 Q13363 1
Rrna processing 0.3405969180658304 0.5646218132970826 0.5723310251352307 1.0 0.940161695770491 155 P27635,Q9UNQ2,O75691,P46776,P62280,P08865,P83881,Q07020,P61353,P46778,Q8IY81,Q9Y5J1,Q9GZL7,P18077,Q9Y3U8,Q9H0D6,Q9BVP2,Q9Y2P8,Q9H0A0,P05388,P61247,P84098,O60832,P30050,P35268,P18124,P62266,P62277,Q13868,P62841,P32969,P61313,Q969X6,P62701,Q15024,Q8IY37,P61513,Q9BQ52,P62829,P62910,P18621,P36578,P62241,P39019,P46781,Q9BV38,P62244,Q2NL82,Q9Y221,P63220,P55769,P15880,P39023,P49207,Q02543,P62753,P62424,P62249,P40429,Q14137,P61927,P26373 62
Signaling by tgfb family members 0.3225804381656794 0.557159864102393 0.5774182092428584 1.0 0.9429666179384376 22 Q96PU5,P61586,Q9Y624,Q9Y3F4,Q13547,Q93008 6
Dag and ip3 signaling 0.4396108509099244 0.5567721127299419 0.5776831397166424 1.0 0.9429666179384376 7 Q13555,Q05655 2
Transcription of e2f targets under negative control by dream complex 0.5590654820664771 0.5561619654531212 0.5781001376305999 1.0 0.9429666179384376 3 Q13547,P11388 2
Signaling by scf kit 0.4249661016413992 0.5488354983896473 0.5831183465731631 1.0 0.9489297392247852 8 O14757,P40763,P07948,P63000 4
Dex h box helicases activate type i ifn and inflammatory cytokines production 0.6305921052631671 0.5443300550277436 0.5862143683516048 1.0 0.9526873361980244 2 Q9H2U1 1
Diseases of programmed cell death 0.3116226582980901 0.5413774997031989 0.5882474125735653 1.0 0.9528240066453216 24 P20810,P04632,P07384,Q07021,Q00535 5
Metabolism of lipids 0.3459211048174669 0.5382629978356597 0.5903954930373554 1.0 0.9551927082474286 169 Q96G23,P11310,Q9UJ83,Q15392,Q15738,O75521,P37268,P51648,O14735,O60488,O00154,P09960,P33121,P38435,O00767,Q15648,Q9Y305,Q96N66,Q9NVC6,O00763,P05165,O43808,Q16850,P35610,O95470,O95864,Q9UBF8,Q96SU4,Q06136,P09110,Q13085,P48163,P34913,O95772,P42765,Q9NZ01,Q14914,Q9Y6B6,Q9BV79,Q01469 40
Energy dependent regulation of mtor by lkb1 ampk 0.4347102231427849 0.5363434421923153 0.5917212119482085 1.0 0.9562269701204806 7 P49815 1
Nervous system development 0.3615227715060971 0.5336760314433229 0.5935656948560697 1.0 0.9563346747870078 215 Q00169,Q9HAU5,Q12955,P27635,Q15008,O94973,P46776,P62280,O75116,Q92747,P08865,P83881,Q07020,P25786,P46778,Q14997,Q96CW1,P05388,P18077,Q9Y3U8,O15511,P98155,P61247,P84098,P00533,P35998,P30050,Q16850,P35268,P18124,Q15370,P63000,O75122,P32969,O14786,P61313,Q92769,P35080,Q9BUF5,P62701,P61513,Q9BVA1,P62829,P17612,P62910,O00487,P16333,O95239,O15144,P18621,P36578,Q8N8S7,P62241,P39019,P46781,Q9BPU6,P63220,P15880,P39023,Q8TEY7,Q15375,O15145,P04350,Q02543,P62753,Q00535,P62249,P25789,P51665,P62424,Q01518,P40429,P61586,P07948,P61927,P26373 76
Interleukin 12 signaling 0.3064444579296141 0.5279592246428801 0.5975276371767 1.0 0.9589354822432524 27 Q99439,Q00169,Q13126,P38646,P07237,P14174,P37837,Q9H3K6,P04179,P11233,P60953,Q9UL46,P05388 13
Nuclear events stimulated by alk signaling in cancer 0.3708555340255836 0.5123099595541907 0.6084340959701251 1.0 0.9667615585818404 12 P40763,P51608,P63208,P27361,P62753,Q9HC35,Q13616 7
Dna damage recognition in gg ner 0.3498320952139606 0.5114035907121108 0.6090684811293403 1.0 0.9667615585818404 15 Q9UNS2 1
Rho gtpases activate iqgaps 0.3705903833162076 0.5110096099322979 0.6093443276632131 1.0 0.9667615585818404 12 Q9BVA1,P04350,P63000 3
Regulation of tnfr1 signaling 0.4230010531975013 0.4884749514300448 0.6252134638307896 1.0 0.9709279321251836 7 O14920 1
Fcgamma receptor fcgr dependent phagocytosis 0.2908342184879774 0.4797257100583445 0.6314224438628342 1.0 0.975498230229201 32 O15511,Q05655,Q92747,Q9UQB8,O15145,O00159,P16333,O15144,P07948,Q9Y2A7 10
Condensation of prometaphase chromosomes 0.3833875190569766 0.4750504271302811 0.634751031031934 1.0 0.975498230229201 10 O95067 1
Ca dependent events 0.4182261437564676 0.4693649388210978 0.6388088051265588 1.0 0.975498230229201 7 Q13555,Q05655 2
Sars cov 2 infection 0.2997243395901413 0.4674996324598661 0.6401424549867747 1.0 0.975498230229201 24 Q9H0U3,Q99873,Q96SB4,P48729,P78362,P14314,P46977,Q9UQN3,Q14697,P55072,P61803,P17844,P27824,P39656 14
Oncogene induced senescence 0.46413056226719 0.465299029470437 0.6417173297133338 1.0 0.975498230229201 5 P11802,Q9HCE1,P27361 3
Activation of the ap 1 family of transcription factors 0.6049342105263261 0.4601416886056044 0.6454145224854422 1.0 0.975498230229201 2 P27361 1
Neurotransmitter release cycle 0.4616823349635949 0.4566212499467635 0.6479433026918158 1.0 0.975498230229201 5 P51649 1
Protein methylation 0.4312903206417973 0.4561041663618005 0.648315074301149 1.0 0.975498230229201 6 P13639,P15880,O60678 3
Trna processing 0.2612221022827798 0.4560526664510833 0.6483521063958253 1.0 0.975498230229201 53 P78406,Q9H974,Q9UBP6,Q9Y224,Q9BQ52,Q9UET6,Q9Y3I0,Q96PZ0,P07814,Q9NRG9,Q6YHU6,Q99575,Q7Z3B4,Q92499,Q5VV42,P57081 16
Downregulation of smad2 3 smad4 transcriptional activity 0.430511293218432 0.4531682015403726 0.650427627919572 1.0 0.975498230229201 6 Q13547,Q96PU5 2
Galactose catabolism 0.6026315789473787 0.452876838950363 0.650637429545943 1.0 0.975498230229201 2 Q96G03 1
Tnf signaling 0.389902556828373 0.4522916344484561 0.6510589017173098 1.0 0.975498230229201 9 O14920,P63244 2
Mtorc1 mediated signalling 0.3659021199341257 0.4505990413049378 0.6522785577311949 1.0 0.975498230229201 11 P62753,Q96B36 2
Rhof gtpase cycle 0.3136818194636701 0.4462240244735068 0.6554354305577426 1.0 0.975498230229201 19 P43121,Q8TAA9,P42166,Q5JTV8 4
Alpha oxidation of phytanate 0.5006856000806968 0.4406926706879279 0.6594355033671349 1.0 0.975498230229201 4 P51648,Q9UJ83 2
Caspase activation via extrinsic apoptotic signalling pathway 0.5235274761434814 0.4397404760301691 0.6601250834160157 1.0 0.975498230229201 3 P49327,Q13546 2
Synthesis of ip3 and ip4 in the cytosol 0.5983552631579052 0.4395206096612988 0.6602843518569199 1.0 0.975498230229201 2 Q01968 1
Regulation by c flip 0.5980263157894842 0.4385006104806956 0.6610234277091729 1.0 0.975498230229201 2 P49327 1
Caspase activation via death receptors in the presence of ligand 0.5980263157894842 0.4385006104806956 0.6610234277091729 1.0 0.975498230229201 2 P49327 1
Rac2 gtpase cycle 0.2795836622717449 0.420375136678995 0.6742114284389109 1.0 0.9825268389320828 33 Q68EM7 1
Vldl assembly 0.589473684210537 0.4123613043637133 0.6800746210877737 1.0 0.9825268389320828 2 P07237 1
Ldl remodeling 0.589473684210537 0.4123613043637133 0.6800746210877737 1.0 0.9825268389320828 2 P07237 1
Chylomicron clearance 0.5894736842105371 0.412361304363713 0.680074621087774 1.0 0.9825268389320828 2 P01130 1
Regulation of pyruvate dehydrogenase pdh complex 0.4014048260176088 0.4041533312149602 0.6860999695057917 1.0 0.9873318776049256 7 Q8NCN5 1
Sema4d induced cell migration and growth cone collapse 0.4168418602136014 0.4027566472444766 0.6871272566116706 1.0 0.9877897507327732 6 P61586 1
Signaling by met 0.307186207709246 0.398055949944352 0.6905889439205892 1.0 0.9905340824232788 18 P62330 1
Neurotransmitter clearance 0.5842105263158006 0.3966496217202976 0.6916258549932794 1.0 0.9905340824232788 2 P05091 1
Developmental biology 0.343617165031485 0.3785095975670279 0.705052065379357 1.0 1.0 263 Q15008,O94973,O75116,Q07020,Q14574,Q96CW1,Q9Y3U8,P98155,P84098,P00533,Q9NVC6,P35998,Q16850,Q08554,P61313,P35080,Q9BPU6,P04632,P39023,P04350,P14923,P62753,P62249,Q01518,P61586,P61927,Q9HAU5,Q12955,P46776,P08865,P83881,P25786,P15924,Q86X55,P18077,P40763,P61247,P30050,P35268,P18124,Q15370,P63000,O14786,Q92769,Q9BUF5,P61513,O00487,P16333,O95239,Q8N8S7,P19022,P39019,P46781,Q8TEY7,Q02543,Q00535,P40429,P26373,Q00169,P62280,P46778,O15511,Q13951,P61964,P62701,Q9BVA1,P62910,O15144,P18621,P36578,P15880,P07384,O15145,P07948,P27635,Q92747,Q14997,P05388,Q15648,P62487,O75122,P32969,P62829,P17612,P62241,P63220,Q15375,P25789,P51665,P62424 90
Tp53 regulates transcription of cell cycle genes 0.322991309154755 0.3779640471084159 0.7054573025047564 1.0 1.0 15 A5YKK6,O95628,Q86X55,Q99873 4
Mtor signalling 0.3165638179377243 0.3765894153348407 0.7064787549783367 1.0 1.0 16 P62753,P49815,Q96B36 3
Mitochondrial iron sulfur cluster biogenesis 0.4797711716790753 0.3752870167230531 0.7074470208834227 1.0 1.0 4 Q86SX6,Q9H1K1 2
Cellular response to chemical stress 0.2441388465818131 0.3702912636501638 0.7111654825286768 1.0 1.0 76 Q15008,P25786,Q14997,Q86X55,P09601,P40763,Q05655,Q15648,P35998,P30043,Q8TCT9,P53004,P04179,O00487,P30041,Q8TED1,P30044,P63208,P25789,P51665,Q96HE7,Q9BSH4 22
Role of abl in robo slit signaling 0.4360012933801683 0.3693731019408412 0.7118496441815922 1.0 1.0 5 O75122 1
Inositol phosphate metabolism 0.4290418175831447 0.3470256348940045 0.7285720602396042 1.0 1.0 5 Q01968,Q9NPH2,Q13572,Q9BW91 4
Eph ephrin mediated repulsion of cells 0.3345711720323198 0.345242541457316 0.7299120391414671 1.0 1.0 12 P07948,Q15375,Q96CW1 3
Citric acid cycle tca cycle 0.2918915041879935 0.3344216800265684 0.7380613819350414 1.0 1.0 19 P07954,P50213,Q6P587 3
Sema4d in semaphorin signaling 0.3708454480138123 0.3314859129387414 0.7402774799325342 1.0 1.0 8 O75116,P61586 2
Transcription of the hiv genome 0.2783661726656987 0.3276602242061655 0.7431685809713975 1.0 1.0 23 P29083 1
Fceri mediated ca 2 mobilization 0.4616842026580464 0.3224286357161617 0.7471279934301687 1.0 1.0 4 P07948 1
Inactivation of cdc42 and rac1 0.4765111824198135 0.3038401741419283 0.7612496582042525 1.0 1.0 3 P63000 1
Shc1 events in erbb2 signaling 0.4745011445508279 0.2985717110596937 0.7652668526928841 1.0 1.0 3 Q05655 1
Cyclin d associated events in g1 0.359621133257771 0.2917242585390699 0.7704974599711769 1.0 1.0 8 P07948,Q13616,P63208 3
Negative feedback regulation of mapk pathway 0.4697179197571439 0.2862289448435942 0.7747027759309295 1.0 1.0 3 P27361 1
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.3537817857177924 0.2719037129457821 0.7856960562450777 1.0 1.0 8 Q86X55,Q99873 2
Notch1 intracellular domain regulates transcription 0.3770859543165421 0.269898097757155 0.7872386506581233 1.0 1.0 6 Q92769,P63208,Q13547 3
Metabolism of fat soluble vitamins 0.3611328314099015 0.2639931917645067 0.7917851649014538 1.0 1.0 7 Q6NUM9 1
Copii mediated vesicle transport 0.2547806896610908 0.2570529098858533 0.7971379287611706 1.0 1.0 30 O00743 1
Sumoylation of transcription cofactors 0.3190934768889963 0.2544500589365898 0.7991478817554811 1.0 1.0 11 Q13363 1
Endosomal vacuolar pathway 0.4354158191893606 0.252566519833969 0.8006032046420781 1.0 1.0 4 P04439 1
Microrna mirna biogenesis 0.3169428388457163 0.2465366555563776 0.8052668328560997 1.0 1.0 11 P62487,Q9UPY3,O75569 3
Hedgehog off state 0.229742876670294 0.2454865170047052 0.8060797467093035 1.0 1.0 49 Q15008,P43686,P25786,Q14997,P55036,Q9UNM6,P48729,P35998,P13861,P28066,P62191,Q9UL46,P25788,Q13200,Q9BUF5,Q9BVA1,P17612,O00487,P49720,P63208,P62333,P60900,P25789,P04350,P51665,O00232,Q13616,Q96J02 28
Ovarian tumor domain proteases 0.325723299680245 0.2428893124091352 0.8080911451570332 1.0 1.0 10 P61586,Q7Z434 2
Transmission across chemical synapses 0.238796911874241 0.2338295431693415 0.815117313143308 1.0 1.0 38 Q9UM54,P05091,O94973,Q9BVA1,O94925,P17612,P08754,P04350,Q13555,P51649,P63000,Q96CW1 12
Mrna editing 0.5203947368421188 0.2317428704802279 0.8167377318055098 1.0 1.0 2 Q9NRW3 1
Bmal1 clock npas2 activates circadian gene expression 0.4262350481753968 0.2302410523077953 0.8179044634858994 1.0 1.0 4 Q86X55,Q15648 2
Rho gtpases activate formins 0.2254787372178594 0.2272057844418935 0.8202637299774818 1.0 1.0 59 Q92674,P35080,Q9P258,Q9BVA1,P50748,Q12834,P61586 7
Interleukin 3 interleukin 5 and gm csf signaling 0.3472396851103111 0.2218158051767261 0.8244572751834314 1.0 1.0 7 P07948 1
Signaling by ntrk2 trkb 0.4208336655320825 0.2176381591958842 0.8277110503350606 1.0 1.0 4 Q00535 1
Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0.2783205806910632 0.2152490887980198 0.829573120451947 1.0 1.0 16 Q13951,Q99496,O96019,Q96GM5 4
Synthesis of dna 0.2290855255584912 0.214091010098397 0.8304760861774885 1.0 1.0 83 P41440 1
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.3261702834740023 0.2140436323613025 0.830513031855614 1.0 1.0 9 Q13547,Q96PU5 2
Protein folding 0.2392549123578577 0.2083734381192801 0.8349373944420115 1.0 1.0 33 P40763,Q9BVA1,Q9H0D6,P04350,P36404,P40227,P61758 7
Myogenesis 0.3792881714635445 0.2063816818938723 0.8364927785623342 1.0 1.0 5 P19022,P60953 2
Sumoylation of dna methylation proteins 0.4148489810735508 0.2041439413789049 0.8382410170363199 1.0 1.0 4 Q99496 1
Translation of sars cov 1 structural proteins 0.3387149917627683 0.1976954445265638 0.843283354114849 1.0 1.0 7 Q13724,P14314,Q14697,P26572,P27824,Q10472 6
Budding and maturation of hiv virion 0.2954910205428229 0.196534925868597 0.8441914987887602 1.0 1.0 12 Q96PU5 1
Insulin processing 0.329327702424726 0.1958913421576849 0.8446952139435548 1.0 1.0 8 Q8NEW0 1
Glutathione conjugation 0.2875389910854461 0.1955274322625443 0.8449800642654846 1.0 1.0 13 Q8WUX2,P14550,P21266 3
Phospholipid metabolism 0.2297190366679309 0.1939504921738739 0.846214647230038 1.0 1.0 38 O14735 1
Runx2 regulates bone development 0.4100225233441741 0.1936259095352635 0.8464688092348436 1.0 1.0 4 Q13951,P27361 2
Wax and plasmalogen biosynthesis 0.4073994045717194 0.1880474080783783 0.8508394877643508 1.0 1.0 4 O00116 1
Cytoprotection by hmox1 0.214844570327222 0.1878326023265095 0.851007877654083 1.0 1.0 65 P40763,Q05655,Q15008,Q15648,P63208,P25789,P35998,P51665,O00487,P30043,P25786,Q14997,Q8TCT9,P53004,Q86X55,Q9BSH4,P09601,Q13616 18
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.3452504804545032 0.1812556559216073 0.8561669108872034 1.0 1.0 6 O95628 1
Neddylation 0.2129128453037503 0.1787790928995635 0.8581111622378621 1.0 1.0 65 Q15008,P25786,Q14997,P55036,Q9UNS2,Q13564,Q9UNM6,O60826,Q13617,P35998,Q15370,Q15369,P61964,O00487,P49720,Q16531,P63208,P62333,P60900,P25789,Q8TBC4,P51665,Q9H0A8,Q13616 24
Purine salvage 0.4020664691381832 0.1770079081946697 0.8595021778262693 1.0 1.0 4 P55263,P07741 2
Regulation of ifna signaling 0.420533070088862 0.1762559468492485 0.8600928694688508 1.0 1.0 3 P42224,P18031 2
Regulation of ifng signaling 0.420533070088862 0.1762559468492485 0.8600928694688508 1.0 1.0 3 P42224,P18031 2
Loss of function of mecp2 in rett syndrome 0.3634240529053825 0.1694230690226391 0.865463879336392 1.0 1.0 5 P17612 1
Assembly and cell surface presentation of nmda receptors 0.3026572903909726 0.1689696626805545 0.865820503926346 1.0 1.0 10 Q13555,Q9BVA1,P04350 3
Metabolism of rna 0.1735040824752924 0.1613570371122394 0.8718122026213178 1.0 1.0 438 Q15008,Q07020,Q16637,Q9GZL7,P57081,Q9H0D6,Q9Y3U8,P78406,A5YKK6,O60231,P84098,P35998,Q99575,Q9UBP6,P61313,P62304,Q9BQA1,O43143,O43447,Q92917,Q9H974,Q2NL82,P55769,P39023,P62753,P62249,Q6P2Q9,Q14137,Q9BUJ2,Q7Z3B4,O95628,P61927,Q9HAU5,P46776,O14744,P08865,P83881,P25786,Q8IY81,Q92499,Q9Y5J1,P18077,Q9Y2P8,P61247,P14866,P30050,P18124,P35268,Q8NI27,O95400,Q05519,Q13868,Q969X6,P62314,P16383,P61513,Q9Y3Y2,Q96F86,Q96DI7,O00487,O43172,O60508,P39019,P46781,Q02543,P07814,Q96PZ0,Q6YHU6,O43660,Q5VV42,P41223,P40429,P26373,O43148,Q9UNQ2,P09234,P62280,Q00839,P62826,P61353,P46778,Q8IYB3,Q9BVP2,Q9H0A0,Q9UNM6,Q9UQ35,O60832,P62266,Q8TEQ6,P62277,P62701,P62910,P18621,P36578,P62316,P15880,P04792,Q9NRG9,Q9Y224,O75691,P27635,Q14997,O94906,P05388,Q05655,P62487,Q9UET6,Q9Y3I0,P32969,Q8IY37,Q9BQ52,P62829,Q12996,P62241,Q9BV38,Q9Y221,P63220,P55795,P25789,P51665,P62424 121
Mhc class ii antigen presentation 0.2105276555671782 0.1561679765098224 0.8759006180378042 1.0 1.0 51 Q9Y6B6,O94979,O94973,O43747,Q9BVA1,Q9NZ32,Q10567,Q96CW1,P47756 9
Glycogen metabolism 0.306271369180285 0.1560550681456799 0.8759896147828077 1.0 1.0 9 P06737,P11216,P35573,P13807 4
Maturation of sars cov 1 spike protein 0.354626275930198 0.1507027711105369 0.8802101871734382 1.0 1.0 5 Q14697,P14314,P27824,P26572 4
Dna methylation 0.3881487891679692 0.1501234955832016 0.8806671832521342 1.0 1.0 4 P26358 1
Dna replication 0.2210112361384547 0.1474552361807047 0.8827727097849754 1.0 1.0 89 P41440 1
Signaling by nuclear receptors 0.2080448151230583 0.1468189474649436 0.8832749288378834 1.0 1.0 57 Q99873,O00767,P08559,Q15648,P62487,O60216,P00533,P04792,O14646,P08754,Q01469,Q13547,Q86X55,Q8NBN7,Q13951 15
Signaling by hedgehog 0.2064008988618693 0.1403735923864472 0.8883648214689639 1.0 1.0 54 Q15008,P43686,P25786,Q14997,P55036,Q9UNM6,P48729,P35998,P13861,P28066,P62191,Q9UL46,P25788,Q13200,Q9BUF5,P07237,Q9BVA1,P17612,O00487,P49720,P55072,P63208,P62333,P60900,P25789,P04350,P51665,O00232,Q6P1J9,Q13616,Q96J02 31
Rora activates gene expression 0.3974745266768821 0.1359503014521069 0.8918605697745299 1.0 1.0 3 Q15648 1
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.305883078834805 0.1345135870564485 0.892996467811952 1.0 1.0 8 Q93008,P68036,P22314 3
Nod1 2 signaling pathway 0.3124403908604052 0.1322898705284645 0.8947550191068354 1.0 1.0 7 O14920,Q15750 2
Cytosolic sulfonation of small molecules 0.3224202723880224 0.1288407795638656 0.897483637003051 1.0 1.0 6 O95861 1
Mrna splicing minor pathway 0.2201673698254079 0.1261866721908956 0.8995841610832607 1.0 1.0 29 P62304,P62314,P62316,P55769,P62487,Q96DI7,O94906 7
Prolonged erk activation events 0.3378333882120566 0.1185538665042274 0.9056288166866217 1.0 1.0 5 P28482,Q02750,P46109,P27361 4
Infectious disease 0.2491650265794369 0.1161206511139557 0.9075569223058984 1.0 1.0 338 Q9H0U3,Q7L0J3,Q15008,O94973,O43747,P29083,O75116,Q07020,Q14204,Q96CW1,Q9Y3U8,P78406,P84098,P00533,P35998,P49356,P61313,P39748,Q9Y2A7,P63208,P39023,P12268,P04350,P08754,P62753,Q10567,O00159,P62249,Q7Z3B4,P61927,P46776,P08865,P83881,P25786,P18077,Q15185,P61247,P30050,P18124,P35268,Q15370,P61803,P54709,P63000,Q92769,Q9BUF5,P61513,O00487,P16333,P00558,P39019,Q9UQB8,Q02543,P40429,P26373,Q96PU5,P62280,P46778,O15511,P48729,P62701,Q9BVA1,P62910,P04439,O94776,O15144,P18621,P36578,Q99873,P15880,O15145,Q9NRG9,Q9UKL0,P07948,P27635,Q92747,Q14997,P09601,P05388,P62487,P32969,P62829,P78362,P17612,P62241,Q96SB4,Q99816,P63220,P25789,P51665,P62424,Q13547 92
Rhot1 gtpase cycle 0.4509868421052785 0.1129282627233553 0.910087429238051 1.0 1.0 2 P52306 1
Beta catenin independent wnt signaling 0.1935026052197169 0.1038089740157479 0.9173209447151528 1.0 1.0 51 Q15008,O94973,P25786,Q14997,Q96CW1,P55036,Q9UNM6,P35998,Q9HCE1,Q08209,P63000,Q9UL46,O00487,P49720,P62333,Q00610,P25789,P60900,P51665,O00232,P61586 21
Rhov gtpase cycle 0.250050083943651 0.1025570132549635 0.918314561324724 1.0 1.0 14 P16333,Q8TAA9 2
Cellular responses to stimuli 0.2072714697309483 0.1012368789135894 0.919362421951012 1.0 1.0 316 Q15008,Q07020,Q14204,Q9Y3U8,P78406,P84098,P35998,P30043,Q8TCT9,P61313,P04179,P05198,P54198,Q8TED1,P63208,P39023,P04350,P62753,P10412,P62249,Q7Z3B4,P61927,P54652,P46776,P08865,P83881,P25786,Q86X55,Q9HCU5,P18077,P40763,Q15185,P61247,P30050,P18124,P35268,P53004,Q15370,Q13868,Q969H8,Q9BUF5,P61513,O00487,P30044,P38606,P39019,P46781,Q02543,Q9BSH4,Q13616,P40429,P26373,P07305,P62280,Q13555,P61353,P47755,P46778,Q92616,Q9UNM6,Q99496,P62266,P62277,P62841,Q13217,Q15369,P62701,Q15024,Q96B36,Q9BVA1,P62910,Q9HB90,P18621,P36578,P42345,P62244,P38646,P21283,P15880,P04792,P60900,P49207,Q96HE7,Q9NRG9,O94979,P27635,Q9NZ32,Q14997,P09601,P05388,Q05655,Q15648,P32969,P47756,P62829,P30041,O76024,P62241,P63220,P25789,P51665,P62424 102
Ptk6 regulates cell cycle 0.440131578947385 0.1001202741061973 0.9202488397946949 1.0 1.0 2 P11802 1
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.440131578947385 0.1001202741061973 0.9202488397946949 1.0 1.0 2 P11802 1
Rna polymerase iii transcription 0.2813595586214407 0.0963484722511172 0.9232438148333482 1.0 1.0 9 Q9UKN8,Q12789 2
Rho gtpases activate rocks 0.2736437909494333 0.094507849381733 0.9247057474506186 1.0 1.0 10 P61586 1
Programmed cell death 0.2127118005951736 0.0938467014085828 0.925230932999745 1.0 1.0 100 P41440,P10412,P40763,P15924 4
Synthesis of pyrophosphates in the cytosol 0.4319078947368546 0.0913834963968279 0.9271878748430862 1.0 1.0 2 Q13572 1
Rna polymerase iii transcription initiation from type 1 promoter 0.2853027156858811 0.0904802036383136 0.9279056246287568 1.0 1.0 8 Q9UKN8,Q12789 2
Pcp ce pathway 0.1845104943114984 0.0865020136179999 0.9310673554378266 1.0 1.0 48 Q9UNM6,Q15008,O94973,P62333,Q00610,P25789,P60900,P35998,P51665,O00487,P49720,P25786,Q14997,P63000,P61586,Q96CW1,P55036 17
Ephrin signaling 0.3459512837393047 0.0856951549700759 0.9317087537352478 1.0 1.0 4 Q16512,O00560,P63000 3
Signaling by rho gtpases miro gtpases and rhobtb3 0.2083976427960712 0.084835532969818 0.9323921441306116 1.0 1.0 242 P41440,Q08378,Q92747,Q68EM7,P51648,O15173,P15924,Q12834,O15511,P43121,Q05655,Q8TAA9,Q9UM54,P50748,Q9BXS4,Q07021,P42166,O75122,P35080,Q9P258,Q9BVA1,P16333,O15144,Q5JTV8,P11182,Q92888,Q92674,Q9UQB8,O15145,P14923,Q9NRG9,P61586 32
Mapk1 erk2 activation 0.4203947368421194 0.0804881280870643 0.9358490380147376 1.0 1.0 2 P28482 1
Oas antiviral response 0.3502873186043663 0.075875556410298 0.9395181039458078 1.0 1.0 3 Q6L8Q7 1
Er to golgi anterograde transport 0.1747621472644346 0.0754370133017536 0.9398670107391542 1.0 1.0 71 Q9Y6B6,O94979,Q9UBF2,Q12955,P53621,Q5JRA6,P49257,Q9BVA1,P04350,Q9NZ32,Q14204,Q9Y3B3,O00743,Q9HCU5,P47756 15
Rho gtpase cycle 0.2234266218745373 0.0714556103976591 0.943035151977365 1.0 1.0 148 P41440,Q08378,Q68EM7,P51648,O15173,P15924,P43121,Q8TAA9,Q9UM54,Q9BXS4,Q07021,P42166,P16333,Q5JTV8,P11182,Q92888,Q9UQB8,P14923,Q9NRG9,P61586 20
Rho gtpase effectors 0.2045005532523168 0.0704996384655028 0.9437959882985224 1.0 1.0 111 O15511,Q92674,Q05655,P35080,Q9P258,Q9BVA1,Q92747,P50748,Q9UQB8,O15145,P16333,O15144,Q12834,P61586 14
Regulation of hmox1 expression and activity 0.1710572821368728 0.0681407387567371 0.9456736008634852 1.0 1.0 45 Q05655,Q9UNM6,Q15008,P63208,P62333,P60900,P25789,P35998,P51665,O00487,P49720,P25786,Q14997,Q8TCT9,P09601,Q13616,P55036 17
Aggrephagy 0.2264656804864366 0.0652811772099044 0.947950128783074 1.0 1.0 15 Q14204,Q9BVA1,P04350,Q99497 4
Regulation of runx2 expression and activity 0.1737231379294121 0.0646350639254489 0.9484645660937252 1.0 1.0 41 Q15008,P43686,P25786,Q14997,P55036,Q9UNM6,P35998,P28066,P42224,P62191,Q9UL46,Q13951,Q9UNE7,P25788,O00487,P49720,P63208,P62333,P60900,P25789,P51665,O00232,Q13616 23
Mitochondrial translation 0.1687023311894508 0.0644183682366578 0.948637104664536 1.0 1.0 47 Q7Z2W9,O75616,Q9H9J2,Q9BYD3,P51398,P82675,Q7Z7H8,Q9H2W6,P09001,Q9NP92,Q5T653 11
Class i mhc mediated antigen processing presentation 0.1958063457077049 0.0643262179761813 0.948710477755605 1.0 1.0 111 O94979,Q15008,Q96PU5,O14920,O00161,Q9NZ08,P22314,P25786,Q14997,Q12834,Q9UBS8,P61619,O95376,Q5T4S7,P35998,O94822,Q15370,Q13867,O95714,P04439,P60468,P52888,Q9Y6B6,P63208,Q9Y4B6,P25789,P51665,Q5VTB9,Q96J02 29
Degradation of gli1 by the proteasome 0.1743464169676655 0.0640118680355702 0.948960776863958 1.0 1.0 40 Q15008,P43686,P25786,Q14997,P55036,Q9UNM6,P35998,P28066,P62191,Q9UL46,P25788,P17612,O00487,P49720,P63208,P62333,P60900,P25789,P51665,O00232,Q13616,Q96J02 22
Acyl chain remodeling of cl 0.3983552631579112 0.0636485304072201 0.9492500883755384 1.0 1.0 2 P55084 1
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.1816371858393052 0.0603836409849728 0.951850087483714 1.0 1.0 31 P54652,Q15185,Q9BUF5,Q9BVA1,P04350,Q9NZ32,Q14204,P47756 8
Uch proteinases 0.165151796013585 0.0590740612882295 0.9528931186446972 1.0 1.0 43 Q9Y5K5,Q15008,P43686,P25786,Q14997,P55036,Q9UNM6,Q99496,P35998,P28066,P62191,Q9UL46,O96019,P25788,O00487,P49720,P51610,Q9Y265,P62333,P60900,P25789,P51665,O00232 23
Degradation of beta catenin by the destruction complex 0.1626474001974094 0.0588187702823776 0.9530964578198988 1.0 1.0 47 Q9UNM6,Q15008,P63208,P62333,P48729,P60900,P25789,P35998,P51665,Q13363,O00487,P49720,P25786,Q14997,Q13547,Q13616,P55036 17
Tp53 regulates transcription of death receptors and ligands 0.3868421052631743 0.0567413517531715 0.9547512331238456 1.0 1.0 2 P49327 1
Transport to the golgi and subsequent modification 0.1606332086736699 0.0566814658710645 0.9547989383684472 1.0 1.0 75 Q9Y6B6,O94979,Q9UBF2,Q12955,P53621,Q5JRA6,P49257,Q9BVA1,P04350,Q9NZ32,Q14204,Q9Y3B3,O00743,P47756 14
Signaling by moderate kinase activity braf mutants 0.2457855698198264 0.0524649689104868 0.9581582076343624 1.0 1.0 11 Q13555 1
Mapk6 mapk4 signaling 0.1467770573856198 0.0498108788835991 0.9602730973506256 1.0 1.0 48 Q15008,P25786,Q14997,P55036,Q9UNM6,P35998,Q9HCE1,P63000,Q9UL46,P17612,O00487,P49720,P62333,P04792,P25789,P60953,P51665,O00232,P60900 19
The role of gtse1 in g2 m progression after g2 checkpoint 0.1304329743211037 0.0462682858084358 0.9630964164854984 1.0 1.0 49 Q9UNM6,Q15008,Q9BUF5,Q9BVA1,P62333,P60900,P25789,P04350,P35998,P51665,O00487,P49720,P25786,Q14997,O95067,P55036 16
Synthesis of pips at the plasma membrane 0.2563426688632627 0.0391800249847145 0.9687468591598348 1.0 1.0 7 Q01968,P61106,Q9BTU6,O00443,Q13614,P20339 6
Met interacts with tns proteins 0.33388157894738 0.0377813346426149 0.9698620265434392 1.0 1.0 2 P05556 1
Copi independent golgi to er retrograde traffic 0.1484301517714591 0.0355556069627719 0.971636706431869 1.0 1.0 27 Q9BUF5,Q9BVA1,P04350,Q9NZ32,Q14204,P47756 6
Processive synthesis on the lagging strand 0.2077042356950045 0.0265472344099081 0.9788208592480694 1.0 1.0 13 P49643,Q9Y2S7,P49005,P39748,P28340 5
Maturation of sars cov 2 spike protein 0.2148130376967876 0.0216526897784837 0.9827250030017536 1.0 1.0 12 Q9H0U3,P14314,P46977,P61803,P27824,P39656 6
Beta oxidation of hexanoyl coa to butanoyl coa 0.2477882944384952 0.0201762414515021 0.9839027806028326 1.0 1.0 4 P30084 1
Beta oxidation of lauroyl coa to decanoyl coa coa 0.2477882944384952 0.0201762414515021 0.9839027806028326 1.0 1.0 4 P30084 1
Formation of the beta catenin tcf transactivating complex 0.2125015820036611 0.0050044428212552 0.9960070490043822 1.0 1.0 10 Q9Y4A5 1
Erks are inactivated 0.2085667215815483 0.0034077001619228 0.9972810539152148 1.0 1.0 7 Q8IV63,Q14738,P51452,P27361,P28482,P30153 6
Negative regulation of mapk pathway 0.2087042532146404 0.0013157086160509 0.9989502167116158 1.0 1.0 9 Q14738,P53041,Q02750,P27361,P28482,P30086,P30153,P31946 8