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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:d94a0f151ae5d0a4e26c93b161680398aca18a38b8d7249df5f8e18d8ab7f247
+size 71856

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 3053,
+    "annotations_size": 53,
+    "title": "Average number of proteins per term",
+    "value": 2.792452830188679
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C307/C307_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.9399999999999956	1.4760826220525978	0.1399217134443349	0.9996607552514462	0.3905838522826939	3	Q9H3G5,Q9HB40	2
+Histidine acid phosphatase active site [IPR033379]	0.8351360209767411	1.0654253785833354	0.2866834772923092	0.9999999832520736	0.5627490480182367	2	P11117	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ACVR1B", "ADSS", "AKT1", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CAPN5", "CASP2", "CASP3", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EGFR", "EIF2AK2", "EPHA7", "FASN", "G6PD", "GAA", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "IKBKB", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K4", "MAPK1", "MAPK3", "MASTL", "MDH1", "MDH2", "MTMR2", "MTMR6", "NEK9", "NME1", "NME2", "NME3", "PAK2", "PBK", "PGAM1", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRKCD", "PRPF4B", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1"], "leading_proteins": ["ACP2", "CPVL", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Beta tubulin, autoregulation binding site [IPR013838]", "1": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Beta tubulin, autoregulation binding site [IPR013838]", "1": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:72da0989fc54c8c894e387a6b098d071860de3de6e0a0c9962a0dd02256ca3fa
+size 70031

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Beta tubulin, autoregulation binding site [IPR013838]	5	6	2.207560025853926	0.027274958300081	3.5533980582524274	5.54126213592233	0.5823511994709325	0.3808337519133083	1.5578062452886454	0.9632803779920796	1.1906256051626651	0.3058955364405814	1.0	1.0	1.0	1.0	9.4206715064497e-07
+EF-Hand 1, calcium-binding site [IPR018247]	9	35	2.039570051296878	0.0413931674824981	10.019417475728156	36.70631067961165	0.9532938980945532	0.3894555773109194	3.76037227687173	3.057484685571999	1.1082350706804749	0.3408841825650379	0.0783121346174081	0.0060275441501108	0.0402942577421927	0.0430672573908121	0.0014287535135353

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3053,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.612903225806452
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C307/C307_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Beta tubulin, autoregulation binding site [IPR013838]	0.8467344929438825	2.207560025853926	0.027274958300081	0.5756805010655531	0.1875122367993526	6	Q9BVA1,P04350,P68371,Q13885,P07437	5
+EF-Hand 1, calcium-binding site [IPR018247]	0.5361650976304027	2.039570051296878	0.0413931674824981	0.7303154146139048	0.2138646986595735	35	O43852,Q9Y680,P41208,P80303,O95202,Q96AY3,Q02818,O95302,Q9NWM8	9
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.7758112094395255	0.8367269873185209	0.4027460459473877	0.999999884938497	0.6571119697036326	2	P34896	1
+Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]	0.5152409046214246	0.1266765942508999	0.8991963716572577	1.0	0.9291695840458328	2	O75600	1
+Peptidase M16, zinc-binding site [IPR001431]	0.3305427043110431	0.0555558110277038	0.9556956677934754	1.0	0.9556956677934754	5	P22695	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Legume lectin, beta chain, Mn/Ca-binding site [IPR019825]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ACVR1B", "ADSS", "AKT1", "AKT2", "APEX1", "APOBEC3C", "AURKA", "BPNT1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CETN2", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "EGFR", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LRP2", "LYN", "MACF1", "MAP2K1", "MAP2K4", "MAP4K5", "MAPK1", "MAPK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO9B", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKN1", "PKN2", "PLK1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TBK1", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "CETN2", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "LETM1", "NUCB1", "NUCB2", "SHMT1", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin, conserved site [IPR017975]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin, conserved site [IPR017975]", "1": "Mini-chromosome maintenance, conserved site [IPR018525]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:67393ba96e050a48a0a1818e3c3144cdc33e3070cbc9b8b40b098ff63c533765
+size 83515

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Tubulin, conserved site [IPR017975]	5	6	2.207560025853926	0.027274958300081	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.0	1.0	1.0	1.0	0.0001429815632908
+Proteasome beta-type subunit, conserved site [IPR016050]	2	8	2.108866151876309	0.0349561365959218	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	0.0066883318944571	1.0	0.0039135152062846	0.0015031185668187	0.0105668672564949

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3053,
+    "annotations_size": 278,
+    "title": "Average number of proteins per term",
+    "value": 2.6546762589928057
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C307/C307_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,32 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tubulin, conserved site [IPR017975]	0.8467344929438825	2.207560025853926	0.027274958300081	0.9995415976773532	0.3156776943596278	6	Q9BVA1,P04350,P68371,Q13885,P07437	5
+Proteasome beta-type subunit, conserved site [IPR016050]	0.7790194372453412	2.108866151876309	0.0349561365959218	0.9999494081152646	0.3156776943596278	8	P28072,P49721	2
+Syntaxin/epimorphin, conserved site [IPR006012]	0.7710868443595541	1.8835865355933343	0.0596209245250698	0.9999999621363874	0.3882210137533669	6	O60499,Q9P2W9	2
+Haem oxygenase conserved site [IPR018207]	0.9921337266470012	1.6959762125948556	0.0898903850139043	0.9999999999957532	0.4645356860493714	2	P09601	1
+Tetraspanin, conserved site [IPR018503]	0.96229508196721	1.5589031491558376	0.1190193048802483	0.9999999999999994	0.4830453843370136	3	O60637,O43657	2
+Guanylate kinase, conserved site [IPR020590]	0.7678739456342714	1.422494430828335	0.1548827671123629	1.0	0.5520180674004731	4	Q14168	1
+Sterol reductase, conserved site [IPR018083]	0.9121599475581876	1.3730490626053031	0.169737094746085	1.0	0.5607041077001685	2	Q14739	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.8489019993444771	1.1197910603298191	0.2628028096980372	1.0	0.6323474812096868	2	P04066	1
+DnaJ domain, conserved site [IPR018253]	0.4976272801081696	0.8325537054724675	0.4050964774113903	1.0	0.7167362042248897	9	Q96KC8	1
+C-type lectin, conserved site [IPR018378]	0.7312356604392116	0.6739434629018581	0.5003472585632638	1.0	0.8121739736218754	2	Q9UBG0	1
+Sugar transporter, conserved site [IPR005829]	0.71049180327866	0.6478035951774228	0.5171119898014667	1.0	0.8210680327057037	3	P11166,Q7L0J3	2
+Dynamin, GTPase region, conserved site [IPR019762]	0.7174696820714477	0.625876803305646	0.5313957505763602	1.0	0.8299326891024053	2	P50570	1
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.6899377253359502	0.5336238390553029	0.5936018115134236	1.0	0.8690123661143703	2	P15880	1
+Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]	0.5374610275260343	0.5217919731118681	0.6018151790713993	1.0	0.8690123661143703	4	P42345,Q9UBF8	2
+ABC transporter-like, conserved site [IPR017871]	0.3958498781766195	0.3452550740370178	0.7299026181351795	1.0	0.9018352348514664	9	Q9UG63,P08183,Q03518	3
+Ribosomal protein L7Ae conserved site [IPR004037]	0.6047197640117932	0.2909528949549399	0.7710873460188279	1.0	0.9282817125316936	2	P62424	1
+Actin, conserved site [IPR004001]	0.5912815470337509	0.2598987965827786	0.7949418395732673	1.0	0.940399282559014	2	O96019	1
+Thioredoxin, conserved site [IPR017937]	0.3441206449546419	0.1930805146289842	0.8468959125902449	1.0	0.9732028353645684	11	Q9H1E5	1
+Profilin conserved site [IPR027310]	0.5424450999672141	0.1659695077016462	0.8681809466561616	1.0	0.9732028353645684	2	P07737	1
+Heat shock protein Hsp90, conserved site [IPR019805]	0.5127868852458998	0.1419385903279015	0.8871285122129118	1.0	0.986486905580758	3	P07900,P08238	2
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.4926253687315534	0.1007899146805647	0.9197172329894808	1.0	0.9948692247901778	2	P05067	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.4926253687315534	0.1007899146805647	0.9197172329894808	1.0	0.9948692247901778	2	P05067	1
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.4926253687315534	0.1007899146805647	0.9197172329894808	1.0	0.9948692247901778	2	P05067	1
+Phosphorylase pyridoxal-phosphate attachment site [IPR035090]	0.4788593903638032	0.0878361509026528	0.9300069045288116	1.0	0.9972304634290212	2	P06737	1
+Clathrin adaptor complex, small chain [IPR000804]	0.460983606557381	0.0754761104833895	0.9398359043827468	1.0	0.9972304634290212	3	Q92572,P61923	2
+GTP1/OBG, conserved site [IPR006074]	0.3959357587676057	0.0450821753431536	0.964041808991742	1.0	1.0	2	P55039	1
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.3913470993116944	0.0440196339194628	0.964888753431419	1.0	1.0	2	P10644	1
+Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]	0.3890527695837379	0.0435235504441425	0.9652841917711924	1.0	1.0	2	P29692	1
+S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]	0.3739757456571556	0.0407884199207398	0.9674645712418464	1.0	1.0	2	P23526	1
+Oxysterol-binding protein, conserved site [IPR018494]	0.3335519842571339	0.0354814269735908	0.9716958561775476	1.0	1.0	4	Q96SU4,P22059,Q9BZF1	3
+Mini-chromosome maintenance, conserved site [IPR018525]	0.3088283557597587	0.0140416618698463	0.9887967429417102	1.0	1.0	6	Q14566,P33993,P49736,P25205,P33992	5

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site [IPR020611]", "Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site [IPR014783]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GPCR, family 2, secretin-like, conserved site [IPR017983]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubby, C-terminal, conserved site [IPR018066]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADGRE5", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARIH2", "ATAD1", "ATP5C1", "ATP5O", "ATP7A", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT1", "BCAT2", "BCS1L", "BDH2", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAP2", "CAPZA1", "CAPZA2", "CAPZB", "CBL", "CBR1", "CBX1", "CBX3", "CBX4", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CDYL", "CECR2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF7", "DCP2", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC1", "DSC2", "DSC3", "DSG2", "DTYMK", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IGF1R", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "ITGAV", "IVD", "KDM2A", "KDSR", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRP2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP6", "MPST", "MRC2", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NID1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP2", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAM", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF3", "PHGDH", "PHIP", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS3", "PMS1", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RECQL5", "REL", "RNF14", "RNF2", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC2A4", "SLC4A2", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SORL1", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TBL1XR1", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TULP3", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP33", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VLDLR", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCF2", "ACTL6A", "AHCY", "AP3S1", "APP", "COPZ1", "DNAJC1", "DNM2", "DRG2", "EEF1D", "FUCA1", "HMOX1", "HSP90AA1", "HSP90AB1", "LBR", "MCM2", "MCM3", "MCM5", "MCM6", "MCM7", "MPP2", "MRC2", "MTOR", "OSBP", "OSBPL8", "OSBPL9", "PFN1", "PI4KB", "PRKAR1A", "PSMB2", "PSMB6", "PYGL", "RPL7A", "RPS2", "SLC2A1", "STX10", "STX18", "SV2A", "TAP1", "TMX4", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "1": "EF-hand domain [IPR002048]", "2": "Tubulin/FtsZ, GTPase domain [IPR003008]", "3": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "1": "EF-hand domain [IPR002048]", "2": "Tubulin/FtsZ, GTPase domain [IPR003008]", "3": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "4": "Importin-beta, N-terminal domain [IPR001494]", "5": "Immunoglobulin-like domain [IPR007110]", "6": "TGS [IPR004095]", "7": "MCM N-terminal domain [IPR027925]", "8": "MCM, AAA-lid domain [IPR041562]", "9": "MCM OB domain [IPR033762]", "10": "MCM domain [IPR001208]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:884c66aa47a194a79fd273864527e324c08ba7a908d78440061a4d11c4094bf1
+size 228492

interpro_domain/df_merge.tsv

@@ -0,0 +1,6 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	5	10	2.275406544503398	0.0228815531479413	3.1262135922330097	10.111650485436892	0.9686720267359892	0.3700536707457866	1.7316562118191232	1.203619216216406	0.9607394322697528	0.3108814801432357	0.000515770772327	0.0016377422378922	0.0066572828402184	0.0033939033653995	8.104989222609044e-07
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	2	6	2.2449802507854177	0.0247694004261544	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0096486309970478	0.0550816697898294	0.0056684159955205	0.0331187861076589	0.018020673376298
+EF-hand domain [IPR002048]	11	41	2.242499749191994	0.0249290915002555	12.385922330097088	43.512135922330096	1.0171858714399242	0.3947118087831401	4.608360476919044	4.087317384177653	1.201458704248258	0.3652478399429377	0.1330503697075844	0.0115064399742295	0.0714976342213511	0.0349265103093486	0.0010527524380771
+Tubulin/FtsZ, GTPase domain [IPR003008]	5	6	2.207560025853926	0.027274958300081	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.0	1.0	1.0	1.0	0.0001429815632908
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	5	6	2.207560025853926	0.027274958300081	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.0	1.0	1.0	1.0	9.937036022358197e-05