diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d999d79dcec5fe98e3fe983816ea381488412f73 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bdfda589d60a1c051f9f0d32a995692b80ba482d0b4ce88cd76a72c77f33cb1c +size 71820 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0c9d7920a250ce18ccde56674349302793885e23 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 53, + "title": "Average number of proteins per term", + "value": 2.792452830188679 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..78e9cc29a672bea2f3a9515af06e52840b6d82a3 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d8ad346d7b25812c9254c835b98217505765da09 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Serine carboxypeptidase, serine active site [IPR018202] 0.9150819672131104 1.645783258843623 0.0998083901999997 0.9962002683859263 0.2784128779263151 3 Q9HB40,P10619 2 +Tyrosine-protein kinase, active site [IPR008266] 0.6664708104613555 1.5548668838308703 0.119977775831455 0.998856692848006 0.3088638282491021 7 P08069,Q15375,P00533 3 +Cysteine peptidase, asparagine active site [IPR025661] 0.9442805637495966 1.5212080864701785 0.128207626820382 0.9993051477615444 0.3088638282491021 2 P07858 1 +Cysteine peptidase, histidine active site [IPR025660] 0.9442805637495966 1.5212080864701785 0.128207626820382 0.9993051477615444 0.3088638282491021 2 P07858 1 +Histidine acid phosphatase active site [IPR033379] 0.8574237954769084 1.1628584865159188 0.2448869229258135 0.9999996575197376 0.4635359612524327 2 P11117 1 +Cysteine peptidase, cysteine active site [IPR000169] 0.5358261087526897 0.8277239753744005 0.4078268379988903 0.9999999999991296 0.6754632004356621 6 P07858 1 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6e4dff309bc4f8a5e02cb0634253314f19b45e2e --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ACVR1B", "ADSS", "AKT1", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CAPN5", "CASP2", "CASP3", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EGFR", "EIF2AK2", "EPHA7", "FASN", "G6PD", "GAA", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "IKBKB", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K4", "MAPK1", "MAPK3", "MASTL", "MDH1", "MDH2", "MTMR2", "MTMR6", "NEK9", "NME1", "NME2", "NME3", "PAK2", "PBK", "PGAM1", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRKCD", "PRPF4B", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1"], "leading_proteins": ["ACP2", "CTSA", "CTSB", "EGFR", "EPHA7", "IGF1R", "SCPEP1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/advanced/plot_0.png b/interpro_binding_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..60a220d538bb67c497320e61ef9260b5f1feda98 --- /dev/null +++ b/interpro_binding_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eb245ae810d6d3eeac3c0eaa2b3af273724d4e47b8ba1a44459bb1dad41fee61 +size 186807 diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..10e8eeba27932c124b42dde09eed12d360760c29 --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]", "1": "Beta tubulin, autoregulation binding site [IPR013838]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b75eed42b4e711351ddb53c790867e1435f256e8 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d0d6b09b2483c3bedd89f4fe9983a1478cb38b4c844fef5531e272745859966d +size 139237 diff --git a/interpro_binding_site/basic/plot_1.png b/interpro_binding_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..aa25ee0552d7d49aab3e077f5a80710882303fa1 --- /dev/null +++ b/interpro_binding_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a9fe0c484e6cda6e741f6e64fee8ee024ec46b987c6fd410240859c61fd3ac0e +size 142013 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..f29a0fe491787e7ceb850ea5377324c1766a0396 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:92e609af18fdd6fadd61054a73f50d03bfc4e7f99812b32ce7940e131932510f +size 69781 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..920c4f83709669358b2a5b2d9efc93c94795304d --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +EF-Hand 1, calcium-binding site [IPR018247] 15 35 2.297945259733813 0.0215649048748849 10.019417475728156 36.70631067961165 0.9532938980945532 0.3894555773109194 3.76037227687173 3.057484685571999 1.1082350706804749 0.3408841825650379 1.5102493358374857e-05 0.3175327074700926 0.0402942577421927 0.002958524345255 9.448901657314716e-07 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..aa5db840880d0db24744de70a1d3e0509c0ed3e5 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 31, + "title": "Average number of proteins per term", + "value": 4.612903225806452 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5e2dac52caed6f1da3b52ff9bb07bd6a9ba1e53f --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..147643ac1198e2b3b641c526f48f80fd56f72182 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EF-Hand 1, calcium-binding site [IPR018247] 0.5935804333599862 2.297945259733813 0.0215649048748849 0.491263758056134 0.2308828301858899 35 O95302,Q02818,Q9Y680,Q9H223,P80303,Q9H4M9,O95202,Q6NUK1,Q9BRK5,P41208,P0DP25,Q9BPX6,Q14257,Q9NWM8,O43852 15 +Beta tubulin, autoregulation binding site [IPR013838] 0.4886773875943626 0.6033890978648769 0.5462498731287617 0.9999999999770216 0.7697157303178006 6 P04350,Q9BVA1,Q9BUF5,P07437,P68371 5 +Protein kinase, ATP binding site [IPR017441] 0.326094201127647 0.1716108024169046 0.863743514350996 1.0 0.905245156023876 47 Q15375,P36896,P31751,Q86UE8 4 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b4cf8d416900465870c156c2d63a0225ed3500f2 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Legume lectin, beta chain, Mn/Ca-binding site [IPR019825]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ACVR1B", "ADSS", "AKT1", "AKT2", "APEX1", "APOBEC3C", "AURKA", "BPNT1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CETN2", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "EGFR", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LRP2", "LYN", "MACF1", "MAP2K1", "MAP2K4", "MAP4K5", "MAPK1", "MAPK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO9B", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKN1", "PKN2", "PLK1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TBK1", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["ACVR1B", "AKT2", "CALM3", "CALU", "CETN2", "EHD1", "EHD4", "EPHA7", "FKBP14", "FKBP7", "FKBP9", "LETM1", "MICU1", "NUCB1", "NUCB2", "RCN2", "SDF4", "SLC25A24", "TLK2", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6c1b043338bcd6bcdebe887daadbf8b5c81d8ad2 --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "EGF-like calcium-binding, conserved site [IPR018097]", "1": "Syntaxin/epimorphin, conserved site [IPR006012]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ba02537c0a265bac764d7a50978837775226a12f --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2e2277d6b9f31d82166d358ced5a9334b131eb89c74a6b79c0f56a2c6f517404 +size 188246 diff --git a/interpro_conserved_site/advanced/plot_1.png b/interpro_conserved_site/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..36d6fdef449a2b4a88d93bd4ee415e51a70ea720 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0486a7bb4ee108aa177d54a9e0698c2b66d85458290fb9d257b6035d09e7db8e +size 186547 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..4711889b5a19e3bffae49c72b7ccc5c52bc61198 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EGF-like calcium-binding, conserved site [IPR018097]", "1": "Syntaxin/epimorphin, conserved site [IPR006012]", "2": "Tubulin, conserved site [IPR017975]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..68da1f8f69863fac86b454e8a7f6f86a26691f21 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6ae8b893897feffc4b6a1fa49f66d098a76ad7454a94cdedb40e1a78c562017a +size 146125 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..e9696d7ed5df06f4b5a344afa8fe217eff6c2e03 --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d9097305f1611cd301ae72f76d2ba2e1b3d50da6ba8d17ba32777dcde19834d0 +size 144809 diff --git a/interpro_conserved_site/basic/plot_2.png b/interpro_conserved_site/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..3a4df9bcfb15e45fdd39e87ba88e117053aeb959 --- /dev/null +++ b/interpro_conserved_site/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c7247efcb11784a47f8e1ae1143a3361350e681842377a0a5ce8cbf7ca600ec3 +size 136527 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c221dcb9d72b8a1ab0fd5dc0e57d4e73de0431e7 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f2572b644d064cd5363f6c7c618f29112a2e777b07dc929567ad1b4d20a7d23b +size 80414 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2fe73eadd3eb479680ae75aaa1bcd68527952afd --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +EGF-like calcium-binding, conserved site [IPR018097] 6 7 2.7801279151250786 0.0054337490064062 1.1703703703703705 2.466666666666667 -0.1373915694631231 0.3902853831950666 1.067180945982341 1.5160051467387146 1.437469353479462 0.3143260829565273 0.0006097953864012 0.1635258499471353 0.3009165941166509 2.4880325513906888e-05 0.0017617577033715 +Syntaxin/epimorphin, conserved site [IPR006012] 5 6 2.6154611807676336 0.0089107049607024 2.592233009708738 5.847087378640777 0.9961908981999794 0.2839139128702306 1.4759357288864456 1.4239341993278547 1.138258151200134 0.2914162845337057 5.737823424793828e-06 0.0607401038440192 0.1180585699575878 2.831336309208378e-07 1.6279070379868977e-05 +Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415] 4 6 2.3712970304034684 0.0177257794677809 1.062730627306273 1.845018450184502 -0.374757291558179 0.2572252390798428 0.9906082579891434 1.2202031996221276 1.9499632968198624 0.2932843562524823 0.0004396452857286 0.0786913117950012 0.0113213926532688 3.906142953800441e-05 9.937036022358197e-05 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3dba881d40f9826b9fb696619bdc99a0db988ff7 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 278, + "title": "Average number of proteins per term", + "value": 2.6546762589928057 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ef22975cdc183e6ab68a77bdc1817c1d9dcc4d6f --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7be9f58600cf96fae2272ee1bf9595ac5c37edb0 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,27 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EGF-like calcium-binding, conserved site [IPR018097] 0.9326986211424796 2.7801279151250786 0.0054337490064062 0.7801261297149478 0.358232297909642 7 P98164,P48960,P98155,Q07954,P14543,P01130 6 +Syntaxin/epimorphin, conserved site [IPR006012] 0.9209058089924522 2.6154611807676336 0.0089107049607024 0.9169471955817527 0.358232297909642 6 Q13190,O60499,Q9P2W9,O15400,Q13277 5 +Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415] 0.8642904839166773 2.3712970304034684 0.0177257794677809 0.9930704750069768 0.358232297909642 6 P98155,P01130,Q07954,Q92673 4 +Thioredoxin, conserved site [IPR017937] 0.6402152257676984 1.843218735128888 0.0652970805440993 0.9999999929650571 0.3862252849204173 11 Q9H1E5,P07237,Q9H3N1,Q96JJ7 4 +Tetraspanin, conserved site [IPR018503] 0.9426229508196676 1.754605735994299 0.0793267696489621 0.9999999998949652 0.408385962266879 3 O60637,O43657 2 +Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745] 0.9760734185512968 1.6528891983559817 0.0983534158746781 0.9999999999996836 0.4155042840143524 2 P05067 1 +Proteinase inhibitor I2, Kunitz, conserved site [IPR020901] 0.9760734185512968 1.6528891983559817 0.0983534158746781 0.9999999999996836 0.4155042840143524 2 P05067 1 +Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744] 0.9760734185512968 1.6528891983559817 0.0983534158746781 0.9999999999996836 0.4155042840143524 2 P05067 1 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.9731235660439218 1.6406814443418902 0.100863558702005 0.9999999999998542 0.4155042840143524 2 P04066 1 +Sugar transporter, conserved site [IPR005829] 0.9016393442622952 1.5924630353926568 0.1112807024041699 0.9999999999999944 0.4254907589628792 3 Q7L0J3,P11166 2 +C-type lectin, conserved site [IPR018378] 0.9609963946247132 1.5904669582687785 0.1117295877852164 0.999999999999995 0.4254907589628792 2 Q9UBG0 1 +Haem oxygenase conserved site [IPR018207] 0.9472304162569648 1.5334320070824283 0.1251694475248768 1.0 0.4461167488707148 2 P09601 1 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.8938053097345231 1.3123238413892118 0.1894108911925376 1.0 0.5318810883992471 2 P04439 1 +DnaJ domain, conserved site [IPR018253] 0.5547508290065581 1.2056802240194788 0.2279408130875582 1.0 0.5614424082739388 9 Q99543,Q96KC8,Q9Y2G8,Q9NVH1 4 +Guanylate kinase, conserved site [IPR020590] 0.6461134798294459 0.9598110738324688 0.3371503079582076 1.0 0.6841444205283338 4 Q00013,Q92796,Q14168 3 +Sterol reductase, conserved site [IPR018083] 0.752540150770258 0.7482110418841568 0.454332871821969 1.0 0.7634675232368939 2 Q14739 1 +Tubulin, conserved site [IPR017975] 0.4886773875943626 0.6033890978648769 0.5462498731287617 1.0 0.8193693809872534 6 P04350,Q9BVA1,Q9BUF5,P07437,P68371 5 +Dynamin, GTPase region, conserved site [IPR019762] 0.6787938380858802 0.4880456841935798 0.6255174825349461 1.0 0.8373055677830434 2 O00429 1 +Intermediate filament protein, conserved site [IPR018039] 0.4354654998607435 0.482451673042578 0.6294851211030794 1.0 0.8373055677830434 8 P48681,P07196,Q16352,P08670 4 +Oxysterol-binding protein, conserved site [IPR018494] 0.5234503115775623 0.4722012286535635 0.6367831628344343 1.0 0.84250233508583 4 Q9BZF1,P22059,Q96SU4 3 +Polyamine biosynthesis domain, conserved site [IPR030373] 0.6430678466076627 0.3779742632553918 0.7054497131406179 1.0 0.8910050015370763 2 P52788 1 +Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.3965825395067981 0.0953799715960803 0.9240130238942564 1.0 0.9900446087990634 4 P42345 1 +Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.470993117010804 0.0617030289223289 0.9507993278366698 1.0 0.9900446087990634 2 P82675 1 +D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752] 0.4232786885245883 0.050188302504539 0.9599723330566527 1.0 0.9900446087990634 3 Q9GZZ9,O43175 2 +Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.4414945919370626 0.0425853019233297 0.9660321122274452 1.0 0.9900446087990634 2 P29692 1 +Hexapeptide transferase, conserved site [IPR018357] 0.3952802359881911 0.0258732236649184 0.9793584573149084 1.0 0.9933273624799296 2 Q9Y5P6 1 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b7ec2e46e6f275c4b24f8e68cdcdffc042903f70 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site [IPR020611]", "Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site [IPR014783]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GPCR, family 2, secretin-like, conserved site [IPR017983]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubby, C-terminal, conserved site [IPR018066]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADGRE5", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARIH2", "ATAD1", "ATP5C1", "ATP5O", "ATP7A", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT1", "BCAT2", "BCS1L", "BDH2", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAP2", "CAPZA1", "CAPZA2", "CAPZB", "CBL", "CBR1", "CBX1", "CBX3", "CBX4", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CDYL", "CECR2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF7", "DCP2", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC1", "DSC2", "DSC3", "DSG2", "DTYMK", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IGF1R", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "ITGAV", "IVD", "KDM2A", "KDSR", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRP2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP6", "MPST", "MRC2", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NID1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP2", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAM", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF3", "PHGDH", "PHIP", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS3", "PMS1", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RECQL5", "REL", "RNF14", "RNF2", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC2A4", "SLC4A2", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SORL1", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TBL1XR1", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TULP3", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP33", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VLDLR", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", 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@@ +version https://git-lfs.github.com/spec/v1 +oid sha256:45adb36095ec5ba8f4f27e494a82034dd7168487616281be3f474b6d2edd8eac +size 137562 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3e5733c9ce0d7915897eb00d3f55f4b3db356b2f --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4faee6cdf237cd80d42d3fdaf61d669e572f4addfd9e17f0895a7752750f1554 +size 147234 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..23a3220e429f0c4f62278b9118329004b39e638b --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,11 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Immunoglobulin-like domain [IPR007110] 11 16 3.110194766819125 0.001869640181781 4.480582524271845 12.427184466019416 0.4075261998509777 0.4433674298264088 2.6479725987944898 3.173316973839475 1.1756568118942026 0.3233613924696422 0.0059950940032201 1.0 1.0 0.0198065600649204 0.0085829869011754 +EGF-like domain [IPR000742] 8 11 2.9619460620983205 0.0030570133148677 1.812807881773399 3.940886699507389 -0.2515571357977262 0.397990648527913 1.5407225921455587 2.4527963737747185 1.3250723622342764 0.3076599741691995 0.0034615954670857 0.3075216202298709 0.5213291194813008 0.0023719924306961 0.0109943535003159 +EGF-like calcium-binding domain [IPR001881] 6 7 2.7801279151250786 0.0054337490064062 1.1703703703703705 2.466666666666667 -0.1373915694631231 0.3902853831950666 1.067180945982341 1.5160051467387146 1.437469353479462 0.3143260829565273 0.0013423636387488 0.1835089509173778 0.3339976348230559 5.880242055622103e-05 0.0037452233271246 +Immunoglobulin subtype [IPR003599] 7 12 2.57572108896472 0.0100031299463558 2.9684466019417477 8.483009708737864 0.1381371967634491 0.4928258967784709 2.271921156707309 2.9216637549507847 1.0756254869730633 0.312999744433737 0.0980898454346954 1.0 1.0 0.2085219048520711 0.0985362738260494 +Immunoglobulin subtype 2 [IPR003598] 5 10 2.56320360717656 0.0103711208911483 2.8106796116504853 8.04126213592233 0.1764352420775828 0.5005828106358552 2.0581551085254395 2.677802743524345 1.0491539805619012 0.3137632145774063 0.0566839588636807 1.0 1.0 0.0824194625829831 0.1114390039799233 +Target SNARE coiled-coil homology domain [IPR000727] 5 9 2.5449243769250898 0.0109301406601518 3.5024271844660193 8.266990291262136 0.5942034778060385 0.4012381903331891 1.9023475359698396 2.183694577914796 1.0582363712887182 0.3038263160802639 0.0003912809217482 0.1135912525516411 0.2147385524083838 0.0002861885476851 0.0010205277760807 +EF-hand domain [IPR002048] 17 41 2.36907907472027 0.0178324404142469 12.385922330097088 43.512135922330096 1.0171858714399242 0.3947118087831401 4.608360476919044 4.087317384177653 1.201458704248258 0.3652478399429377 4.701393760823703e-05 0.3837477700868037 0.0155897140308174 0.002894195016663 1.2437937569102145e-06 +Immunoglobulin V-set domain [IPR013106] 4 7 2.178423847411077 0.0293744960583206 1.8814814814814815 3.639506172839506 -0.1240957684542258 0.411362008796823 1.3951513136318474 1.5958030613003984 1.3078070990153907 0.3212718057023477 0.0471991190444314 1.0 1.0 0.1988041978590851 0.0229507437408614 +Major facilitator superfamily domain [IPR020846] 3 5 2.093283436988081 0.0363238602987712 1.8883495145631068 4.121359223300971 0.8776223597987594 0.2728824130413255 1.233496960525634 1.4580976091979958 1.2936014196902064 0.266909732326598 0.0316134258098954 1.0 0.2518545844225215 0.1637924032376012 0.0553856285019619 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 4 5 2.0721355443489498 0.0382528023490802 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0108675670250155 1.0 1.0 0.0153906222854723 0.0034992238505004 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e46b36fe37f12f49038040334e01fe2c1d5d4929 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 2548, + "title": "Average number of proteins per term", + "value": 2.1656200941915227 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bd4f392e3f940a27ca15f553a3bc50c43c2b04d0 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..35b9bd32f85e883e42aac91ef2e06e15b66c0267 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,226 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Immunoglobulin-like domain [IPR007110] 0.7968470915361385 3.1101947668191254 0.001869640181781 0.9915052085852842 0.6191743090760238 16 Q9Y624,P35613,P01889,P10321,P10586,P04439,Q08722,Q7KYR7,P43121,Q96J84,Q5ZPR3 11 +EGF-like domain [IPR000742] 0.8583290490249876 2.9619460620983205 0.0030570133148677 0.9995907564888984 0.6191743090760238 11 P98164,P48960,P98155,Q07954,O94813,Q08431,P14543,P01130 8 +EGF-like calcium-binding domain [IPR001881] 0.9326986211424796 2.7801279151250786 0.0054337490064062 0.9999990652109416 0.6191743090760238 7 P98164,P48960,P98155,Q07954,P14543,P01130 6 +Immunoglobulin subtype [IPR003599] 0.7657101186118651 2.57572108896472 0.0100031299463558 0.9999999999925014 0.6191743090760238 12 Q9Y624,P35613,P10586,Q7KYR7,P43121,Q96J84,Q5ZPR3 7 +Immunoglobulin subtype 2 [IPR003598] 0.7901157362494908 2.5632036071765594 0.0103711208911483 0.999999999997092 0.6191743090760238 10 P35613,P10586,P43121,Q96J84,Q5ZPR3 5 +Target SNARE coiled-coil homology domain [IPR000727] 0.8169419469588847 2.5449243769250898 0.0109301406601518 0.9999999999993108 0.6191743090760238 9 Q13190,O60499,O15400,Q86Y82,Q13277 5 +EF-hand domain [IPR002048] 0.5928904213908117 2.36907907472027 0.0178324404142469 1.0 0.6191743090760238 41 O95302,Q02818,Q9Y680,O75071,P80303,Q9H223,Q9H4M9,O95202,Q6NUK1,Q9BRK5,Q8IYU8,P41208,P0DP25,Q9BPX6,Q14257,Q9NWM8,O43852 17 +Immunoglobulin V-set domain [IPR013106] 0.7973001315980195 2.178423847411077 0.0293744960583206 1.0 0.6191743090760238 7 Q9Y624,Q7KYR7,P43121,Q5ZPR3 4 +Major facilitator superfamily domain [IPR020846] 0.8599675315908175 2.093283436988081 0.0363238602987712 1.0 0.6191743090760238 5 Q8NHS3,Q7L0J3,P11166 3 +Zinc finger, ZZ-type [IPR000433] 0.9185212057686012 2.0890419933557887 0.0367039432017171 1.0 0.6191743090760238 4 Q13501 1 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.8549868766404107 2.0721355443489498 0.0382528023490802 1.0 0.6191743090760238 5 Q9HD20,P16615,Q04656,P05023 4 +Immunoglobulin C1-set [IPR003597] 0.8943916038045201 1.9923005301448091 0.0463380935769188 1.0 0.6191743090760238 4 P04439,P10321,Q5ZPR3 3 +MHC class I-like antigen recognition-like [IPR011161] 0.8943916038045201 1.9923005301448091 0.0463380935769188 1.0 0.6191743090760238 4 Q9UNN8,P10321,P04439 3 +Dynamin, N-terminal [IPR045063] 0.7648242224485985 1.924637138166559 0.0542747698414334 1.0 0.6191743090760238 6 Q9H4M9,Q8IWA4,Q9H223,O60313 4 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.7648242224485985 1.924637138166559 0.0542747698414334 1.0 0.6191743090760238 6 Q9H4M9,Q8IWA4,Q9H223,O60313 4 +Fibronectin type III [IPR003961] 0.7047938229965358 1.8651415253864003 0.0621615693032895 1.0 0.6191743090760238 8 Q15375,Q92673,P15260 3 +PB1 domain [IPR000270] 0.9625067025476348 1.8327617742988584 0.066838006120254 1.0 0.6191743090760238 3 Q13501 1 +C-type lectin-like [IPR001304] 0.9613114754098352 1.8280744254082208 0.0675383826023681 1.0 0.6191743090760238 3 Q8IX05,Q9UBG0 2 +CD80-like, immunoglobulin C2-set [IPR013162] 0.844272282725447 1.7885444501711818 0.0736882109161762 1.0 0.6191743090760238 4 Q96J84,P43121 2 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.7872440915738401 1.7799249113180204 0.075088250197995 1.0 0.6191743090760238 5 Q9UIQ6,Q9NZ08,P55786 3 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.7872440915738401 1.7799249113180204 0.075088250197995 1.0 0.6191743090760238 5 Q9UIQ6,Q9NZ08,P55786 3 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.8365916165605796 1.7570026442921196 0.0789173584835294 1.0 0.6303493085142101 4 Q96G23,Q15629 2 +Complement Clr-like EGF domain [IPR026823] 0.936393442622948 1.7300455547554083 0.0836221364962765 1.0 0.6304775971409164 3 Q07954,P14543 2 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.7222736573435307 1.726766028539802 0.0842096918684935 1.0 0.6304775971409164 6 O43169,O15173 2 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.6221521823343549 1.6946694988972992 0.0901381348779812 1.0 0.648790869121741 10 P08069,Q15375,P00533 3 +BRICHOS domain [IPR007084] 0.9809898393969207 1.673228469023432 0.0942823279240949 1.0 0.6489647921368581 2 Q9Y287 1 +Reticulon [IPR003388] 0.9806620780072104 1.6718728071160414 0.0945494060102414 1.0 0.6489647921368581 2 O95197 1 +Syntaxin, N-terminal domain [IPR006011] 0.9199999999999976 1.6652595066271232 0.0958609935100178 1.0 0.6489647921368581 3 O15400,Q13277 2 +Amyloidogenic glycoprotein, heparin-binding [IPR015849] 0.9760734185512968 1.6528891983559817 0.0983534158746781 1.0 0.6489647921368581 2 P05067 1 +Amyloidogenic glycoprotein, E2 domain [IPR024329] 0.9760734185512968 1.6528891983559817 0.0983534158746781 1.0 0.6489647921368581 2 P05067 1 +Beta-amyloid precursor protein C-terminal [IPR019543] 0.9760734185512968 1.6528891983559817 0.0983534158746781 1.0 0.6489647921368581 2 P05067 1 +Amyloidogenic glycoprotein, extracellular [IPR008154] 0.9760734185512968 1.6528891983559817 0.0983534158746781 1.0 0.6489647921368581 2 P05067 1 +Pancreatic trypsin inhibitor Kunitz domain [IPR002223] 0.9760734185512968 1.6528891983559817 0.0983534158746781 1.0 0.6489647921368581 2 P05067 1 +Amyloidogenic glycoprotein, copper-binding [IPR011178] 0.9760734185512968 1.6528891983559817 0.0983534158746781 1.0 0.6489647921368581 2 P05067 1 +VPS10 [IPR006581] 0.9750901343821696 1.6488202782098218 0.0991844593222506 1.0 0.6489647921368581 2 Q92673 1 +Sortilin, C-terminal [IPR031777] 0.9750901343821696 1.6488202782098218 0.0991844593222506 1.0 0.6489647921368581 2 Q92673 1 +Sortilin, N-terminal [IPR031778] 0.9750901343821696 1.6488202782098218 0.0991844593222506 1.0 0.6489647921368581 2 Q92673 1 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.9731235660439218 1.6406814443418902 0.100863558702005 1.0 0.6551479982568448 2 P04066 1 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.6093507767637182 1.624836896627565 0.1041973169379286 1.0 0.6615801095736581 10 O95302,Q9NWM8,Q9Y680 3 +Peptidase M14, carboxypeptidase A [IPR000834] 0.967879383808587 1.6189719160470375 0.1054533058044129 1.0 0.6615801095736581 2 P16870 1 +CD209-like, C-type lectin-like domain [IPR033989] 0.9609963946247132 1.5904669582687785 0.1117295877852164 1.0 0.667537344461159 2 Q9UBG0 1 +ERAP1-like C-terminal domain [IPR024571] 0.9003278688524576 1.58725487136971 0.112454931715239 1.0 0.667537344461159 3 P55786,Q9UIQ6 2 +MENTAL domain [IPR019498] 0.9596853490658832 1.585036251448848 0.112958098005069 1.0 0.667537344461159 2 Q14849 1 +PA domain [IPR003137] 0.9593575876761756 1.5836785233631712 0.1132668945577366 1.0 0.667537344461159 2 P02786 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.8940983606557321 1.562502389934109 0.1181696832901821 1.0 0.6688322874213343 3 P04439,P10321 2 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.8940983606557321 1.562502389934109 0.1181696832901821 1.0 0.6688322874213343 3 P04439,P10321 2 +CBS domain [IPR000644] 0.6824844295456538 1.538355060144633 0.1239618239683457 1.0 0.6688322874213343 6 Q8NE01,P51790 2 +Peptidase C1A, papain C-terminal [IPR000668] 0.9442805637495966 1.5212080864701785 0.128207626820382 1.0 0.6688322874213343 2 P07858 1 +Tyrosine-protein kinase, catalytic domain [IPR020635] 0.6747165119965788 1.501226909491434 0.1332968821487561 1.0 0.6694281176761 6 Q15375,P00533 2 +Ricin B, lectin domain [IPR000772] 0.7205057884351961 1.4844817581932273 0.1376811590609932 1.0 0.6727289824131861 5 Q10472,Q10471,Q9UBG0 3 +Fibronectin type II domain [IPR000562] 0.8725266144423544 1.476639591835371 0.139772272903724 1.0 0.6727289824131861 3 Q9UBG0 1 +Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019] 0.9324811537200977 1.4723148948609663 0.1409358629181012 1.0 0.6729648814895657 2 P06865 1 +Glycoside hydrolase family 20, catalytic domain [IPR015883] 0.9324811537200977 1.4723148948609663 0.1409358629181012 1.0 0.6729648814895657 2 P06865 1 +Cysteine-rich flanking region, C-terminal [IPR000483] 0.9311701081612588 1.4668831578357258 0.1424078428703892 1.0 0.6744520141891296 2 Q13641 1 +Leucine-rich repeat N-terminal domain [IPR000372] 0.9311701081612588 1.4668831578357258 0.1424078428703892 1.0 0.6744520141891296 2 Q13641 1 +Ubiquitin-associated domain [IPR015940] 0.5531172347353639 1.4539281665495285 0.1459662227849776 1.0 0.6757656988588202 13 Q13501 1 +GOLD domain [IPR009038] 0.6637308675685454 1.448544943202945 0.1474647062054384 1.0 0.6757656988588202 6 Q9Y3B3,Q15363 2 +Immunoglobulin I-set [IPR013098] 0.7615027668743316 1.4449212549111865 0.1484800053448527 1.0 0.6757656988588202 4 Q96J84,P10586 2 +Sushi/SCR/CCP domain [IPR000436] 0.9216650278597208 1.4275133484438056 0.1534319803814448 1.0 0.6757656988588202 2 Q6UXD5 1 +Glycoside hydrolase family 2, catalytic domain [IPR006103] 0.9213372664700162 1.4261561761815276 0.1538232663236209 1.0 0.6757656988588202 2 O00462 1 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.8544262295081977 1.404469557706395 0.1601790706230019 1.0 0.6757656988588202 3 P16615,P05023 2 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.8544262295081977 1.404469557706395 0.1601790706230019 1.0 0.6757656988588202 3 P16615,P05023 2 +Glycosyltransferase 2-like [IPR001173] 0.7517294619266782 1.403903747242053 0.160347513677352 1.0 0.6757656988588202 4 Q10472,Q10471 2 +MD-2-related lipid-recognition domain [IPR003172] 0.91510980006556 1.4003766682165464 0.161400553050528 1.0 0.6757656988588202 2 P17900 1 +CALCOCO1/2, zinc finger UBZ1-type [IPR041641] 0.8524590163934302 1.3966220124709536 0.1625272672495197 1.0 0.6757656988588202 3 Q13137,Q86VP1 2 +SKICH domain [IPR041611] 0.8524590163934302 1.3966220124709536 0.1625272672495197 1.0 0.6757656988588202 3 Q13137,Q86VP1 2 +LEM domain [IPR003887] 0.6511123113148904 1.387798627019792 0.1651983730336499 1.0 0.676475954218857 6 P42167,Q86XL3 2 +Intermediate filament head, DNA-binding domain [IPR006821] 0.7468022302394188 1.3832005714166409 0.166603374584942 1.0 0.6781236396843966 4 P07196,Q16352,P08670 3 +Marvel domain [IPR008253] 0.8823336610947331 1.2650423205969406 0.2058561575130246 1.0 0.7289586331481922 2 Q16625 1 +EH domain-containing protein, N-terminal [IPR031692] 0.8767617174696825 1.2421214818963215 0.2141917437523526 1.0 0.7342232894437506 2 Q9H223 1 +Domain of unknown function DUF5600 [IPR040990] 0.8767617174696825 1.2421214818963215 0.2141917437523526 1.0 0.7342232894437506 2 Q9H223 1 +N-acetylgalactosaminyltransferase [IPR045885] 0.8078688524590086 1.218834159706932 0.2229071433476881 1.0 0.7377461831881607 3 Q10472,Q10471 2 +Band 3 cytoplasmic domain [IPR013769] 0.8698787282858071 1.213854535779189 0.2248032766875438 1.0 0.7386190911892921 2 P04920 1 +Bicarbonate transporter, C-terminal [IPR011531] 0.8698787282858071 1.213854535779189 0.2248032766875438 1.0 0.7386190911892921 2 P04920 1 +Zinc finger, CHHC-type [IPR012996] 0.8062295081967208 1.212310230650843 0.2253936491281623 1.0 0.7386190911892921 3 P55795,P31943 2 +CUB domain [IPR000859] 0.8652900688299043 1.195041956715814 0.2320706378508128 1.0 0.7486349894871089 2 Q6UXD5 1 +Coagulation factor 5/8 C-terminal domain [IPR000421] 0.865290068829891 1.195041956715759 0.2320706378508343 1.0 0.7486349894871089 2 Q08431 1 +GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386] 0.8607014093739762 1.1762575064809335 0.2394919908258352 1.0 0.7501950118209032 2 Q8NHH9 1 +Guanylate-binding protein, N-terminal [IPR015894] 0.8607014093739762 1.1762575064809335 0.2394919908258352 1.0 0.7501950118209032 2 Q8NHH9 1 +Guanylate-binding protein/Atlastin, C-terminal [IPR003191] 0.8607014093739762 1.1762575064809335 0.2394919908258352 1.0 0.7501950118209032 2 Q8NHH9 1 +ELMO domain [IPR006816] 0.8551294657489461 1.153488825696977 0.2487098014689337 1.0 0.7598472112024499 2 Q96JJ3 1 +Calcium binding and coiled-coil domain-like [IPR012852] 0.8521796132415782 1.1414543274939015 0.2536809078361068 1.0 0.7615313762135135 2 Q86VP1 1 +MRH domain [IPR044865] 0.7823064300954818 1.1173295931784446 0.2638534267747312 1.0 0.7752125476345019 3 P11717 1 +Glycosyl transferase, family 1 [IPR001296] 0.6806338369999723 1.1045213541570906 0.2693670455976393 1.0 0.7752125476345019 4 Q9BT22,Q2TAA5 2 +FCP1 homology domain [IPR004274] 0.8397246804326448 1.0908075200999905 0.2753575867636262 1.0 0.7761185078249111 2 Q05D32 1 +PSI domain [IPR016201] 0.8289085545722903 1.0470706994726842 0.2950669718999448 1.0 0.79727533870738 2 O15031 1 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8262864634546043 1.036506443693891 0.2999659348340366 1.0 0.8045402125864478 2 Q9NVI7 1 +START domain [IPR002913] 0.8246476565060854 1.029911940350448 0.3030513450749692 1.0 0.8077142544466752 2 Q14849 1 +Saposin B type domain [IPR008139] 0.8236643723369619 1.0259583166020825 0.3049112324467353 1.0 0.8100606263146508 2 P07602 1 +Receptor L-domain [IPR000494] 0.8167813831530686 0.9983501804339892 0.3181095825552704 1.0 0.8219591034680183 2 P00533 1 +Furin-like cysteine-rich domain [IPR006211] 0.8167813831530686 0.9983501804339892 0.3181095825552704 1.0 0.8219591034680183 2 P00533 1 +Diacylglycerol kinase, catalytic domain [IPR001206] 0.8128482464765817 0.98262950487643 0.3257898175782325 1.0 0.8251614862717064 2 Q8TCT0 1 +FAD-binding domain, ferredoxin reductase-type [IPR017927] 0.8085873484103585 0.965647016826301 0.3342208400689466 1.0 0.8334661055077602 2 P16435 1 +Oxidoreductase FAD/NAD(P)-binding [IPR001433] 0.8085873484103585 0.965647016826301 0.3342208400689466 1.0 0.8334661055077602 2 P16435 1 +Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709] 0.8085873484103585 0.965647016826301 0.3342208400689466 1.0 0.8334661055077602 2 P16435 1 +Glycoside hydrolase family 38, N-terminal domain [IPR000602] 0.8069485414618343 0.9591291650345594 0.3374936795134367 1.0 0.8369957201251365 2 O00754 1 +Glycoside hydrolase family 38, central domain [IPR015341] 0.8069485414618343 0.9591291650345594 0.3374936795134367 1.0 0.8369957201251365 2 O00754 1 +Glycosyl hydrolase family 38, C-terminal [IPR011682] 0.8069485414618343 0.9591291650345594 0.3374936795134367 1.0 0.8369957201251365 2 O00754 1 +EB1, C-terminal [IPR004953] 0.8017043592264999 0.93832606605621 0.3480768681687696 1.0 0.8382796409206285 2 Q15555 1 +FAD dependent oxidoreductase [IPR006076] 0.73095221209345 0.9159374271911752 0.3596997149727958 1.0 0.8528165009943465 3 Q96CU9 1 +BTB/Kelch-associated [IPR011705] 0.7869550966896319 0.8802955148747421 0.3786992417043293 1.0 0.854614531621753 2 Q08380 1 +Zinc finger, CW-type [IPR011124] 0.7856440511307747 0.8751740630821772 0.3814792034544261 1.0 0.854614531621753 2 Q8NB78 1 +EH domain [IPR000261] 0.7181811012257993 0.8666929979060338 0.3861102430088432 1.0 0.854614531621753 3 Q9H223 1 +Zinc finger, MYND-type [IPR002893] 0.7091685763650297 0.8322155440487218 0.4052872915638623 1.0 0.859730231651567 3 Q9NRG4 1 +Dynamin, GTPase domain [IPR001401] 0.7084209565966504 0.8293666526804251 0.4068969653530496 1.0 0.860699221666632 3 O60313 1 +Legume-like lectin [IPR005052] 0.7722058341527342 0.8230624734938544 0.4104724675683964 1.0 0.8637449080965566 2 Q12907 1 +FAD/NAD(P)-binding domain [IPR023753] 0.5683503752961143 0.7994387455475738 0.4240360515120698 1.0 0.8717349175962842 5 P09622 1 +Translation initiation factor IF2/IF5 domain [IPR002735] 0.7646673221894673 0.7941582365107386 0.4271033181132351 1.0 0.8758012719919199 2 P55010 1 +v-SNARE, coiled-coil homology domain [IPR042855] 0.6973770491803173 0.787497583173025 0.430990642652616 1.0 0.8758012719919199 3 P51809,O75396 2 +Longin domain [IPR010908] 0.6973770491803173 0.787497583173025 0.430990642652616 1.0 0.8758012719919199 3 P51809,O75396 2 +MRG domain [IPR026541] 0.7607341855129437 0.7791793554396796 0.435874069391259 1.0 0.8767402269138749 2 Q15014 1 +BRO1 domain [IPR004328] 0.7594231399541105 0.7742024974779254 0.4388110516183281 1.0 0.8767402269138749 2 Q8WUM4 1 +GMP phosphodiesterase, delta subunit [IPR008015] 0.7558177646673331 0.760558784838333 0.4469206450679008 1.0 0.8792882137018401 2 A6NIH7 1 +SLC12A transporter, C-terminal [IPR018491] 0.7538511963290894 0.7531436749828534 0.4513635817263601 1.0 0.8792882137018401 2 P55011 1 +Amino acid permease/ SLC12A domain [IPR004841] 0.7538511963290894 0.7531436749828534 0.4513635817263601 1.0 0.8792882137018401 2 P55011 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.7486070140937364 0.7334659677409536 0.4632742772700924 1.0 0.8792882137018401 2 O60506 1 +STAG [IPR013721] 0.7482792527040283 0.732240846970803 0.4640215769376405 1.0 0.8792882137018401 2 Q8WVM7 1 +Stromalin conservative domain [IPR020839] 0.7482792527040283 0.732240846970803 0.4640215769376405 1.0 0.8792882137018401 2 Q8WVM7 1 +Band 7 domain [IPR001107] 0.5158700780413292 0.7318566490009207 0.464256068340608 1.0 0.8792882137018401 6 O75955 1 +ABC transporter type 1, transmembrane domain [IPR011527] 0.5428141769652735 0.6872511566462826 0.4919244723105214 1.0 0.8991726744532716 5 Q03518 1 +Ras-associating (RA) domain [IPR000159] 0.5346395251961785 0.6518567214656182 0.5144936063059156 1.0 0.9149653525789232 5 Q96L92 1 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.7256637168141552 0.6491666598708848 0.5162306590200525 1.0 0.9149653525789232 2 Q14011 1 +Exportin-2, central domain [IPR013713] 0.6567213114754107 0.6375653691043967 0.523756644864366 1.0 0.9149653525789232 3 P55060,O95373 2 +Small GTP-binding protein domain [IPR005225] 0.3808414379467367 0.6263331445959233 0.5310964507316434 1.0 0.9149653525789232 43 P20339,Q15286,Q969Q5,P62820,P51148,Q9NP72,Q9NR31,P51151,P40616,P61026,P61020,Q9H0U4,P11234,Q9Y6B6,Q9BZG1,P36404,Q14964,P61019,P51149,P18085,P11233 21 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.4886773875943626 0.6033890978648769 0.5462498731287617 1.0 0.9238340539532962 6 P04350,Q9BVA1,Q9BUF5,P07437,P68371 5 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.4886773875943626 0.6033890978648769 0.5462498731287617 1.0 0.9238340539532962 6 P04350,Q9BVA1,Q9BUF5,P07437,P68371 5 +OCRE domain [IPR041591] 0.7027204195345788 0.5682191600822832 0.5698861629218233 1.0 0.9382414220713712 2 P52756 1 +Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.4796175367569943 0.5613566509519234 0.5745544292145754 1.0 0.9382414220713712 6 Q9BTU6,P42345 2 +YTH domain [IPR007275] 0.6348361167041139 0.5603268986073182 0.5752564833233507 1.0 0.9382414220713712 3 Q9H6S0 1 +Tudor domain [IPR002999] 0.4481115830312105 0.545153656175149 0.585647842251952 1.0 0.939511599832319 8 Q14739,Q9Y2W6 2 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.4755497210370899 0.542637938256845 0.5873791124540362 1.0 0.939511599832319 6 Q92796,Q14168,Q07157,Q00013,Q9NZW5 5 +Guanylate kinase-like domain [IPR008144] 0.4755497210370899 0.542637938256845 0.5873791124540362 1.0 0.939511599832319 6 Q92796,Q14168,Q07157,Q00013,Q9NZW5 5 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.5408330600196729 0.5367987598240526 0.5914066284188209 1.0 0.9425429163142436 4 Q13596,O60749,Q9Y5X3 3 +AP complex, mu/sigma subunit [IPR022775] 0.4735805710535112 0.5336133504088284 0.5936090696826839 1.0 0.942965030892443 6 Q92572,Q9Y2T2,P61923,P53680,Q96CW1 5 +Importin-beta, N-terminal domain [IPR001494] 0.3948276494817395 0.4901718736233112 0.624012281928443 1.0 0.952279572651054 13 Q92973,Q8TEX9,Q96P70 3 +EF-hand, Ca insensitive [IPR014837] 0.6137704918032787 0.4888907707990058 0.6249190300486949 1.0 0.952279572651054 3 Q13813,O43707 2 +Dynamin GTPase effector [IPR003130] 0.6787938380858802 0.4880456841935798 0.6255174825349461 1.0 0.952279572651054 2 O00429 1 +GTPase effector domain [IPR020850] 0.6787938380858802 0.4880456841935798 0.6255174825349461 1.0 0.952279572651054 2 O00429 1 +Dynamin stalk domain [IPR000375] 0.6787938380858802 0.4880456841935798 0.6255174825349461 1.0 0.952279572651054 2 O00429 1 +Intermediate filament, rod domain [IPR039008] 0.4354654998607435 0.482451673042578 0.6294851211030794 1.0 0.9547215138295496 8 P48681,P07196,Q16352,P08670 4 +Radical SAM [IPR007197] 0.6761717469682014 0.4795536879715335 0.6315447839059489 1.0 0.9552120510519894 2 Q5VV42 1 +Elp3/MiaB/NifB [IPR006638] 0.6761717469682014 0.4795536879715335 0.6315447839059489 1.0 0.9552120510519894 2 Q5VV42 1 +CARG-binding factor, N-terminal [IPR012956] 0.6751884627990765 0.4763850506520854 0.6338000829848198 1.0 0.9552120510519894 2 Q99729 1 +Tim44-like domain [IPR007379] 0.6735496558505352 0.4711234180300283 0.6375526028503591 1.0 0.9581449221254582 2 Q9BRJ2 1 +Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211] 0.6604392002622276 0.4299321088749138 0.6672450277628266 1.0 0.9748511070755056 2 P09960 1 +Nuclear transport factor 2, eukaryote [IPR018222] 0.5054116103640468 0.4076426289321424 0.683536062863795 1.0 0.9770742563224988 4 P61970,Q13283,Q9UBU9 3 +Nuclear transport factor 2 domain [IPR002075] 0.5054116103640468 0.4076426289321424 0.683536062863795 1.0 0.9770742563224988 4 P61970,Q13283,Q9UBU9 3 +Rab-GTPase-TBC domain [IPR000195] 0.4721128608923857 0.3941454446162957 0.6934736610156702 1.0 0.979726778435586 5 Q4KMP7,Q9Y3P9,Q8TC07,Q66K14 4 +L27 domain, C-terminal [IPR014775] 0.6456899377253317 0.3856161291043782 0.6997809861419193 1.0 0.979726778435586 2 Q14168 1 +L27 domain [IPR004172] 0.6456899377253317 0.3856161291043782 0.6997809861419193 1.0 0.979726778435586 2 Q14168 1 +Polyamine biosynthesis domain [IPR030374] 0.6430678466076627 0.3779742632553918 0.7054497131406179 1.0 0.979726778435586 2 P52788 1 +Spermidine synthase, tetramerisation domain [IPR035246] 0.6430678466076627 0.3779742632553918 0.7054497131406179 1.0 0.979726778435586 2 P52788 1 +Phospholipid/glycerol acyltransferase [IPR002123] 0.5732338547290128 0.3613259254394833 0.7178558153003689 1.0 0.979726778435586 3 Q8NF37 1 +NOPS [IPR012975] 0.5698360655737711 0.3513148751876519 0.7253521365181812 1.0 0.979726778435586 3 P23246,Q8WXF1 2 +Thioredoxin domain [IPR013766] 0.336492499359769 0.3210258561814536 0.7481907967023691 1.0 0.979726778435586 24 O95881,Q9H1E5,Q9H3N1,Q96JJ7,Q9Y320,P07237,Q6ZRP7 7 +Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120] 0.6204523107178015 0.3152165083615984 0.7525972721576162 1.0 0.979726778435586 2 Q9Y305 1 +JmjC domain [IPR003347] 0.5290546159547467 0.2407519448838315 0.8097473765948957 1.0 0.979726778435586 3 Q8IUF8 1 +Small acidic protein-like domain [IPR028124] 0.5863651261881264 0.2321356628691272 0.8164326463469613 1.0 0.979726778435586 2 O00193 1 +UBX domain [IPR001012] 0.4238845144357012 0.2197429947257705 0.8260713179996966 1.0 0.979726778435586 5 Q92575,Q96CS3,Q9UNZ2,Q04323 4 +Proteasome component (PCI) domain [IPR000717] 0.3275754930493714 0.2182531999895209 0.8272318364272107 1.0 0.979726778435586 17 Q99627,Q9UNS2,Q9BT78 3 +Pleckstrin homology domain [IPR001849] 0.3153204714246779 0.2124194518673835 0.8317798116358974 1.0 0.979726778435586 20 Q96JJ3 1 +Death domain [IPR000488] 0.5167213114754109 0.2111003658202029 0.8328089547797994 1.0 0.979726778435586 3 Q13546,Q96FV9 2 +DnaJ domain [IPR001623] 0.3362183441690402 0.207521946809986 0.8356022546405233 1.0 0.979726778435586 15 Q9NVH1,Q99543,Q96KC8,Q9UGP8,Q9Y2G8,O60884 6 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.512131147540986 0.2005450461953376 0.8410543317107515 1.0 0.979726778435586 3 Q99797,Q9BYT8 2 +Zinc finger, RanBP2-type [IPR001876] 0.3563108245708526 0.1736454197879365 0.8621441343979497 1.0 0.9804671727646956 9 Q01844,P35637,Q92804 3 +NUC153 [IPR012580] 0.5516224188790531 0.162841175705604 0.8706434874164057 1.0 0.9804671727646956 2 Q9H501 1 +HECT domain [IPR000569] 0.3535765907678967 0.1618241485589335 0.8714443358817905 1.0 0.9804671727646956 9 Q96J02 1 +WW domain [IPR001202] 0.3310245643407981 0.1571383955174226 0.8751357782045881 1.0 0.9804671727646956 14 Q96J02 1 +Sorting nexin, N-terminal [IPR005329] 0.5467059980334217 0.1543260874431083 0.8773526289048827 1.0 0.9804671727646956 2 O60749 1 +Ribosomal Proteins L2, RNA binding domain [IPR022666] 0.5417895771878007 0.1461307869589483 0.8838181428052354 1.0 0.9804671727646956 2 P62917 1 +Ribosomal protein L2, C-terminal [IPR022669] 0.5417895771878007 0.1461307869589483 0.8838181428052354 1.0 0.9804671727646956 2 P62917 1 +EF hand associated, type-2 [IPR013567] 0.5257292690920903 0.1215676481070349 0.9032414364766012 1.0 0.988407083802704 2 Q8IXI1 1 +MIRO domain [IPR020860] 0.5257292690920903 0.1215676481070349 0.9032414364766012 1.0 0.988407083802704 2 Q8IXI1 1 +EF hand associated, type-1 [IPR013566] 0.5257292690920903 0.1215676481070349 0.9032414364766012 1.0 0.988407083802704 2 Q8IXI1 1 +VHS domain [IPR002014] 0.4708196721311404 0.1177790955987712 0.9062426935402212 1.0 0.988407083802704 3 Q92783,Q9UJY4 2 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.4675409836065478 0.1121725322895557 0.9106866077506526 1.0 0.988407083802704 3 Q9ULX6,O43823 2 +ZU5 domain [IPR000906] 0.5165519501802589 0.1090241787016952 0.9131833128116013 1.0 0.9887550128814924 2 Q07157 1 +CDC48, domain 2 [IPR004201] 0.5126188135037636 0.1039733153714634 0.9171905250214794 1.0 0.9887550128814924 2 P46459 1 +CDC48, N-terminal subdomain [IPR003338] 0.5126188135037636 0.1039733153714634 0.9171905250214794 1.0 0.9887550128814924 2 P46459 1 +FCH domain [IPR001060] 0.5047525401507645 0.0944442466789245 0.9247562690902372 1.0 0.9908658425744004 2 Q9UKS6 1 +F-BAR domain [IPR031160] 0.5047525401507645 0.0944442466789245 0.9247562690902372 1.0 0.9908658425744004 2 Q9UKS6 1 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.4981973123565928 0.0870741191955979 0.9306125971236678 1.0 0.9941656687480628 2 O60884 1 +Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.4488524590163902 0.0829227184004584 0.9339129895786108 1.0 0.994170783898926 3 Q9BUJ2,Q1KMD3 2 +Chromo shadow domain [IPR008251] 0.4485245901639333 0.0824503748729837 0.9342885790212428 1.0 0.994170783898926 3 P83916,P45973 2 +Gamma-adaptin ear (GAE) domain [IPR008153] 0.4916420845624326 0.0802084134068507 0.9360714987924694 1.0 0.994170783898926 2 Q9UJY4 1 +Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617] 0.4452459016393516 0.0778034835972358 0.9379843753417738 1.0 0.994170783898926 3 P23193,Q14241 2 +Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.4445901639344153 0.0768907600614075 0.9387104481890932 1.0 0.994170783898926 3 Q9NR33,Q9NRF9 2 +Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297] 0.4877089478859331 0.0763249347272933 0.9391605886577196 1.0 0.994170783898926 2 Q9Y237 1 +Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.4713208784005119 0.0619615669190863 0.950593438319482 1.0 0.994170783898926 2 O15027 1 +Ribosomal protein S5, N-terminal [IPR013810] 0.470993117010804 0.0617030289223289 0.9507993278366698 1.0 0.994170783898926 2 P82675 1 +Ribosomal protein S5, C-terminal [IPR005324] 0.470993117010804 0.0617030289223289 0.9507993278366698 1.0 0.994170783898926 2 P82675 1 +GAT domain [IPR004152] 0.4706653556211001 0.0614455777605302 0.951004355104969 1.0 0.994170783898926 2 Q9UJY4 1 +Nucleotidyl transferase domain [IPR005835] 0.4320931591098395 0.0605441827255764 0.9517222276418188 1.0 0.994170783898926 3 Q9Y5P6 1 +I-kappa-kinase-beta NEMO binding domain [IPR022007] 0.4621435594886796 0.0551254541135315 0.95603851752279 1.0 0.994170783898926 2 O14920 1 +IKBKB, scaffold dimerization domain [IPR041185] 0.4621435594886796 0.0551254541135315 0.95603851752279 1.0 0.994170783898926 2 O14920 1 +Peptidase M41 [IPR000642] 0.4568993772533467 0.0515819704215391 0.9588617857321464 1.0 0.9943170625110874 2 Q9Y4W6 1 +Beta-adaptin appendage, C-terminal subdomain [IPR015151] 0.4226229508196651 0.0494557888263456 0.9605560694624244 1.0 0.9945185126222998 3 Q10567,O00203 2 +Lens epithelium-derived growth factor, integrase-binding domain [IPR021567] 0.4513274336283125 0.0480918500367303 0.961643041420275 1.0 0.9952341468476285 2 Q7Z4V5 1 +Ubiquitin conjugation factor E4, core [IPR019474] 0.4480498197312232 0.0461661326875103 0.9631778358798828 1.0 0.9960134439212424 2 O95155 1 +Elongation factor 1 beta central acidic region, eukaryote [IPR018940] 0.4414945919370626 0.0425853019233297 0.9660321122274452 1.0 0.9965383894556804 2 P29692 1 +Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038] 0.4414945919370626 0.0425853019233297 0.9660321122274452 1.0 0.9965383894556804 2 P29692 1 +PTB/PI domain [IPR006020] 0.4154098360655811 0.0417371729367944 0.9667082200495332 1.0 0.9968322722323798 3 Q9Y3P9,O60343 2 +Heat shock protein Hsp90, N-terminal [IPR020575] 0.3666775992128534 0.0392255161929729 0.9687105903078506 1.0 0.9971548895274728 4 P14625,Q12931,P08238 3 +RWD domain [IPR006575] 0.4339560799737719 0.0388903274854286 0.9689778282849382 1.0 0.9971548895274728 2 Q9UBS8 1 +CTP synthase GATase domain [IPR033828] 0.4313339888561022 0.03770559103017 0.9699224181710306 1.0 0.997321356537444 2 Q9NRF8 1 +CTP synthase, N-terminal [IPR017456] 0.4313339888561022 0.03770559103017 0.9699224181710306 1.0 0.997321356537444 2 Q9NRF8 1 +UAS [IPR006577] 0.4234677155031064 0.0344438290160078 0.9725232336894865 1.0 0.9991198152771594 2 Q96CS3 1 +BAG domain [IPR003103] 0.4009836065573725 0.0281034645787204 0.9775796308319802 1.0 0.9997503572666908 3 O95429,Q9UL15 2 +Extended synaptotagmin, C2A domain [IPR037733] 0.3965912815470284 0.026178454488292 0.9791150008203002 1.0 0.9997503572666908 2 A0FGR8 1 +Synaptotagmin, SMP domain [IPR039010] 0.3965912815470284 0.026178454488292 0.9791150008203002 1.0 0.9997503572666908 2 A0FGR8 1 +Extended synaptotagmin, C2B domain [IPR037749] 0.3965912815470284 0.026178454488292 0.9791150008203002 1.0 0.9997503572666908 2 A0FGR8 1 +Extended synaptotagmin, C-terminal C2 domain [IPR037752] 0.3965912815470284 0.026178454488292 0.9791150008203002 1.0 0.9997503572666908 2 A0FGR8 1 +Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468] 0.3965912815470284 0.026178454488292 0.9791150008203002 1.0 0.9997503572666908 2 A0FGR8 1 +NECAP, PHear domain [IPR012466] 0.391347099311696 0.0250045953084968 0.980051298229643 1.0 0.9997503572666908 2 Q9NVZ3 1 +FDF domain [IPR019050] 0.385119632907234 0.0237657570720577 0.9810394542280104 1.0 0.9997503572666908 2 Q9BX40 1 +DFDF domain [IPR025762] 0.385119632907234 0.0237657570720577 0.9810394542280104 1.0 0.9997503572666908 2 Q9BX40 1 +Lsm14-like, N-terminal [IPR025609] 0.385119632907234 0.0237657570720577 0.9810394542280104 1.0 0.9997503572666908 2 Q9BX40 1 +Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346] 0.3824975417895662 0.0232910494626584 0.9814181112728106 1.0 0.9997503572666908 2 P51784 1 +WSTF/Acf1/Cbp146 [IPR013136] 0.380203212061606 0.0228971870328658 0.9817322842311852 1.0 0.9997503572666908 2 Q9UIG0 1 +Disulphide isomerase [IPR005788] 0.3510498687664045 0.0205912540263954 0.9835717172642467 1.0 1.0 5 Q8NBS9,P13667,Q15084,P07237 4 +Ku70/Ku80 beta-barrel domain [IPR006164] 0.3251392985906187 0.0177883595098055 0.9858076910576914 1.0 1.0 2 P12956 1 +Ku70/Ku80 C-terminal arm [IPR005160] 0.3251392985906187 0.0177883595098055 0.9858076910576914 1.0 1.0 2 P12956 1 +Ku70/Ku80, N-terminal alpha/beta [IPR005161] 0.3251392985906187 0.0177883595098055 0.9858076910576914 1.0 1.0 2 P12956 1 +USP8 dimerisation domain [IPR015063] 0.3244837758112019 0.0177619673219067 0.9858287456505112 1.0 1.0 2 O95630 1 +R3H domain [IPR001374] 0.3675409836065514 0.0048304343970866 0.9961458859606684 1.0 1.0 3 Q9H6S0,O95453 2 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5c038f990593eff37f35e0e3dea774ffdf7c381b --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "AWS domain [IPR006560]", "Abl Interactor 1, SH3 domain [IPR035725]", "Abl-interactor, homeo-domain homologous domain [IPR012849]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acid ceramidase, N-terminal [IPR029130]", "Acid sphingomyelinase/endopolyphosphatase, metallophosphatase domain [IPR041805]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Activin types I and II receptor domain [IPR000472]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adenomatous polyposis coli protein basic domain [IPR009234]", "Adenomatous polyposis coli, N-terminal dimerisation domain [IPR032038]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 1 [IPR041880]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 2 [IPR041882]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apolipoprotein B100 C-terminal [IPR022176]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCL10, CARD domain [IPR042143]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BEACH domain [IPR000409]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-mannosidase, Ig-fold domain [IPR041625]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brd8, Bromo domain [IPR037966]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophilin subfamily 1/2, SPRY/PRY domain [IPR037958]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLIP1, zinc knuckle [IPR032108]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "CNOT4, RNA recognition motif [IPR034261]", "COMM domain [IPR017920]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPPED1, metallophosphatase domain [IPR041867]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium binding and coiled-coil domain-like [IPR012852]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain C2 domain [IPR033884]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carboxypeptidase E, carboxypeptidase domain [IPR034232]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cation/H+ exchanger [IPR006153]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centrosomal CEP44 domain [IPR029157]", "Centrosomal protein of 290kDa, coiled-coil region [IPR032321]", "Centrosomin, N-terminal motif 1 [IPR012943]", "Ceramide kinase, C-terminal domain [IPR045363]", "Chaperone DnaJ, C-terminal [IPR002939]", "Checkpoint kinase 1, catalytic domain [IPR034670]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class IX myosin, motor domain [IPR036023]", "Class VI myosin, motor domain [IPR036114]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complement Clr-like EGF domain [IPR026823]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Copper homeostasis CutC domain [IPR023648]", "Copper type II ascorbate-dependent monooxygenase, C-terminal [IPR024548]", "Copper type II, ascorbate-dependent monooxygenase, N-terminal [IPR000323]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-A, N-terminal APC/C binding region [IPR032447]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "Cytosolic fatty-acid binding [IPR000463]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding domain, Est1-type [IPR018834]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dienelactone hydrolase [IPR002925]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disks Large homologue 3, SH3 domain [IPR035763]", "Disks large homologue 1, N-terminal PEST domain [IPR019590]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5050 [IPR032485]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase RNF220, RING finger [IPR040178]", "E3 ubiquitin-protein ligase RNF220, middle domain [IPR031824]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB-1 binding [IPR009232]", "EB1, C-terminal [IPR004953]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF domain [IPR024731]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERCC4 domain [IPR006166]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAK1/PYK2, FERM domain C-lobe [IPR041784]", "FAM3C (ILEI) domain [IPR039475]", "FAM83, N-terminal [IPR012461]", "FAM91, C-terminal domain [IPR028097]", "FAM91, N-terminal domain [IPR028091]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FRAS1-related extracellular matrix protein, N-terminal domain [IPR045658]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Focal adhesion kinase, N-terminal [IPR041390]", "Focal adhesion kinase, targeting (FAT) domain [IPR005189]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Furin-like cysteine-rich domain [IPR006211]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein, beta subunit [IPR001632]", "G2 nidogen/fibulin G2F [IPR006605]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GH15-like domain [IPR011613]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPCR, family 2-like [IPR017981]", "GPR domain [IPR000965]", "GPS motif [IPR000203]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GS domain [IPR003605]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal [IPR006109]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal [IPR011128]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycosyltransferase subfamily 4-like, N-terminal domain [IPR028098]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Growth factor receptor domain 4 [IPR032778]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Heavy metal-associated domain, HMA [IPR006121]", "Heavy metal-associated domain, copper ion-binding [IPR006122]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homocysteine-binding domain [IPR003726]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Int12, PHD finger [IPR039054]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin alpha-2 [IPR013649]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon gamma receptor, poxvirus/mammal [IPR021126]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KOW [IPR005824]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipid transport, open beta-sheet [IPR009454]", "Lipocalin/cytosolic fatty-acid binding domain [IPR000566]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "LysM domain [IPR018392]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MABP domain [IPR023341]", "MAGE homology domain [IPR002190]", "MAM domain [IPR000998]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MTMR6, PH-GRAM domain [IPR035998]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "Mannosidase Ig/CBM-like domain [IPR041447]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med12 [IPR019035]", "Mediator complex, subunit Med12, LCEWAV-domain [IPR021990]", "Mediator complex, subunit Med12, catenin-binding [IPR021989]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mib-herc2 [IPR010606]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Morc, S5 domain 2-like [IPR041006]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH dehydrogenase subunit 5, C-terminal [IPR010934]", "NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal [IPR001516]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit [IPR001750]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NBR1, PB1 domain [IPR034852]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT, RNA-binding domain [IPR008532]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIDO domain [IPR003886]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT4, modified RING finger, HC subclass (C4C4-type) [IPR039515]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Na-Ca exchanger/integrin-beta4 [IPR003644]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Nck1, SH2 domain [IPR035882]", "Nck1, SH3 domain 1 [IPR035562]", "Nck1, SH3 domain 2 [IPR035564]", "Nck1, SH3 domain 3 [IPR035565]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuropilin, C-terminal [IPR022579]", "Next to BRCA1, central domain [IPR032350]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Olduvai domain [IPR010630]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PCNA-associated factor, histone-like domain [IPR031444]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PDZ-associated domain of NMDA receptors [IPR019583]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PIGA, GPI anchor biosynthesis [IPR013234]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLD-like domain [IPR032803]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Palmitoyltransferase, DHHC domain [IPR001594]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C1A, propeptide [IPR012599]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein kinase B alpha, catalytic domain [IPR034676]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Proto-oncogene c-Rel, RHD, N-terminal subdomain [IPR042845]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM8, RNA recognition motif [IPR033744]", "RED-like, N-terminal [IPR012916]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RQC domain [IPR018982]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rabaptin coiled-coil domain [IPR018514]", "Rabaptin, GTPase-Rab5 binding domain [IPR015390]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad4 beta-hairpin domain 1 [IPR018326]", "Rad4 beta-hairpin domain 2 [IPR018327]", "Rad4 beta-hairpin domain 3 [IPR018328]", "Rad4/PNGase transglutaminase-like fold [IPR018325]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "RecQ helicase-like 5 [IPR010716]", "Receptor L-domain [IPR000494]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Rhs repeat-associated core [IPR022385]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rubisco LSMT, substrate-binding domain [IPR015353]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SAS-6 coiled-coil domain [IPR041513]", "SCAF4, RNA recognition motif [IPR034369]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD3, SET domain [IPR044428]", "SETD7, SET domain [IPR044436]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3PXD2, PX domain [IPR037961]", "SH3PXD2B, SH3 domain 1 [IPR035477]", "SH3PXD2B, SH3 domain 2 [IPR035478]", "SH3PXD2B, SH3 domain 3 [IPR035479]", "SH3PXD2B, SH3 domain 4 [IPR035480]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD2, SET domain [IPR044419]", "SMYD3, SET domain [IPR044420]", "SMYD5, SET domain [IPR044422]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Sequestosome-1, PB1 domain [IPR034866]", "Sequestosome-1, UBA domain [IPR033741]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase greatwall, catalytic domain [IPR037638]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Siah interacting protein, N-terminal [IPR015120]", "Sialidase [IPR011040]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein Lsm3 [IPR034105]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Sphingomyelin phosphodiesterase, C-terminal domain [IPR045473]", "Spindle assembly abnormal protein 6, N-terminal [IPR032396]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulfotransferase domain [IPR000863]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Sushi/SCR/CCP domain [IPR000436]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TANK binding kinase 1, ubiquitin-like domain [IPR041087]", "TANK-binding kinase 1, coiled-coil domain 1 [IPR041309]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TGS [IPR004095]", "THADA/TRM732, DUF2428 [IPR019442]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUP1-like enhancer of split [IPR011494]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Telomerase activating protein Est1, N-terminal [IPR019458]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Teneurin intracellular, N-terminal [IPR009471]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thyroglobulin type-1 [IPR000716]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll-interacting protein, C2 domain [IPR037301]", "Toll-interacting protein, CUE domain [IPR041799]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Tox-GHH domain [IPR028916]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubby, C-terminal [IPR000007]", "Tubby, N-terminal [IPR005398]", "Tuberin, N-terminal [IPR024584]", "Tuberin-type domain [IPR018515]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Lyn, SH2 domain [IPR035852]", "Tyrosine-protein kinase Lyn, SH3 domain [IPR035748]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glucuronate decarboxylase N-terminal [IPR021761]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UMA domain [IPR023340]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Uracil-DNA glycosylase-like [IPR005122]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS9 domain [IPR003123]", "Vacuolar protein 14, C-terminal Fig4-binding domain [IPR021841]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vitellinogen, open beta-sheet [IPR015255]", "Vitellogenin, N-terminal [IPR001747]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA decapping enzyme 2 , NUDIX hydrolase domain [IPR044099]", "mRNA decapping protein 2, Box A domain [IPR007722]", "mRNA splicing factor Cwf21 domain [IPR013170]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ACVR1B", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK2", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "APLP2", "APMAP", "APOB", "APOBEC3C", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMCX3", "ARMT1", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATP7A", "ATXN10", "ATXN2L", "AUP1", "AURKA", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAP18", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCL10", "BCOR", "BCS1L", "BIRC6", "BLVRA", "BLVRB", "BMS1", "BOP1", "BPHL", "BRCA1", "BRD2", "BRD4", "BRD7", "BRD8", "BRD9", "BRIX1", "BROX", "BSG", "BTF3", "BTN2A1", "BUB1B", "BZW1", "BZW2", "C11orf58", "C1orf35", "C2CD5", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CALM3", "CALU", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CASP2", "CASP3", "CBL", "CBX1", "CBX3", "CBX4", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC25", "CCNA2", "CCNB1", "CCNB2", "CD276", "CD2AP", "CD2BP2", "CD302", "CD46", "CD47", "CDC20", "CDC23", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2AIP", "CDYL", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPV", "CEP170", "CEP290", "CEP44", "CEP55", "CERK", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLIC1", "CLINT1", "CLIP1", "CLPB", "CLPX", "CLTC", "CLUH", "CMBL", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT4", "CNPY2", "COA3", "COIL", "COLEC12", "COMMD4", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX6C", "CPD", "CPE", "CPNE1", "CPNE3", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT2", "CRKL", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTC", "CWF19L1", "CXADR", "CYB5B", "CYB5R3", "CYFIP1", "CYFIP2", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCP2", "DCTN1", "DCUN1D4", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DPF2", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUT", "DYNC1H1", "EARS2", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERLIN2", "ERMP1", "ERP29", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM208A", "FAM3C", "FAM49B", "FAM83D", "FAM91A1", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FDFT1", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FOXC1", "FOXRED1", "FREM2", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPS1", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF3C1", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "IAH1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INTS12", "INTS14", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRGQ", "IRS4", "ISCU", "ISOC1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPK1", "IVD", "IWS1", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KIRREL1", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMB1", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8E", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LSS", "LTA4H", "LTN1", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANBA", "MAP2K1", "MAP2K4", "MAP4K5", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MCAM", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED12", "MEPCE", "METAP2", "METTL13", "METTL7A", "MFGE8", "MFN1", "MFSD8", "MIA3", "MICU1", "MICU2", "MID1", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL2", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MVB12A", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA40", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NBR1", "NCAPD2", "NCAPG", "NCBP1", "NCK1", "NCL", "NCLN", "NCSTN", "ND5", "NDUFA10", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFE", "NENF", "NES", "NEU1", "NF1", "NFATC2IP", "NFS1", "NHLRC2", "NHP2", "NID1", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NTHL1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "P3H1", "P3H3", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PALD1", "PALLD", "PAM", "PANK4", "PAPSS1", "PARK7", "PARN", "PARP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDXK", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KB", "PICALM", "PIGA", "PIH1D1", "PIK3C2A", "PIN1", "PIN4", "PINX1", "PIR", "PITHD1", "PITRM1", "PKM", "PKN1", "PKN2", "PLAA", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNN", "PNO1", "PNP", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PXN", "PYCR1", "PYCR2", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABEP1", "RABGAP1", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RALA", "RALB", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "RECQL5", "REL", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOX2", "RIPK1", "RNASEH2A", "RNF14", "RNF2", "RNF219", "RNF220", "RNF40", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRP12", "RSF1", "RTFDC1", "RTN3", "RTN4", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SCAF11", "SCAF4", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SETD1A", "SETD3", "SETD7", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A4", "SLC2A1", "SLC2A4", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPDL3A", "SMS", "SMU1", "SMYD2", "SMYD3", "SMYD5", "SNAP23", "SNAP47", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1", "SPECC1L", "SPEN", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STOML2", "STRBP", "STRN", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TAX1BP1", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMELESS", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TKT", "TLCD1", "TLK2", "TLN1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM97", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TROVE2", "TRRAP", "TSC2", "TSFM", "TSG101", "TSR1", "TST", "TSTA3", "TTC4", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TULP3", "TWF1", "TWISTNB", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UGGT1", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VAT1", "VCP", "VIM", "VIRMA", "VKORC1L1", "VLDLR", "VPS18", "VPS29", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZRANB2", "ZYX"], "leading_proteins": ["ACOT9", "ACTN4", "ADGRE5", "AFG3L2", "AKAP8", "AKAP8L", "ALG1", "ALG11", "ANKLE2", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APP", "ARF4", "ARL1", "ARL2", "ATAD3A", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP7A", "BAG4", "BAG5", "BAZ1B", "BSG", "BTN2A1", "C11orf58", "CALCOCO2", "CALM3", "CALU", "CBX1", "CBX5", "CD276", "CD302", "CD47", "CDKAL1", "CERK", "CERS2", "CETN2", "CIRBP", "CLCN3", "CNNM3", "COPS3", "COPS4", "COPS8", "COPZ1", "CPE", "CSE1L", "CTDSPL2", "CTPS2", "CTSB", "CYB5B", "DLD", "DLG3", "DNAJA2", "DNAJC1", "DNAJC11", "DNAJC16", "DNAJC2", "DNM1L", "EEF1D", "EFCAB14", "EGFR", "EHD1", "EHD4", "EIF5", "ELMO2", "ELOA", "EPHA7", "ERAP1", "ESF1", "ESYT2", "EWSR1", "F11R", "FAF2", "FKBP14", "FKBP7", "FKBP9", "FLOT1", "FOXRED1", "FUCA1", "FUS", "G3BP1", "GALNT1", "GALNT2", "GGA2", "GM2A", "GMPPB", "HDGFL2", "HEXA", "HLA-A", "HLA-B", "HLA-C", "HNRNPAB", "HNRNPH1", "HNRNPH2", "HNRNPUL1", "HNRNPUL2", "HSP90AB1", "HSP90B1", "IFNGR1", "IGF1R", "IGF2R", "IKBKB", "INA", "IPO4", "IPO7", "IPO9", "ITCH", "ITM2B", "KDM1B", "KIRREL1", "LBR", "LDLR", "LETM1", "LGALS3BP", "LMAN2", "LNPEP", "LPCAT1", "LRP1", "LRP2", "LSM14B", "LTA4H", "MAN2B1", "MANBA", "MAPRE2", "MCAM", "MFGE8", "MFN1", "MFSD8", "MICU1", "MICU2", "MIPEP", "MORF4L2", "MPP1", "MPP2", "MPP6", "MRC2", "MRPL45", "MRPS5", "MTOR", "NECAP2", "NEFL", "NES", "NID1", "NLN", "NPEPPS", "NSF", "NSFL1C", "NUCB1", "NUCB2", "NUTF2", "NXF1", "OCLN", "OPA1", "P4HB", "PACSIN3", "PARN", "PDCD6IP", "PDIA4", "PDIA6", "PGRMC2", "PI4K2A", "PIN4", "PLXNB2", "POLE3", "POLE4", "POR", "PROCR", "PSAP", "PSPC1", "PTPRF", "QSOX2", "RAB10", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB39A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABGAP1", "RALA", "RALB", "RBM5", "RCN2", "RHOT2", "RIOX2", "RIPK1", "RNF14", "RPL8", "RTN3", "SAR1A", "SAR1B", "SDF4", "SEC16A", "SEC22B", "SEC63", "SEZ6L2", "SFPQ", "SLC12A2", "SLC25A24", "SLC2A1", "SLC4A2", "SLIT2", "SMS", "SMYD2", "SNX1", "SNX2", "SNX27", "SNX5", "SORL1", "SPTAN1", "SQSTM1", "STAG1", "STAM", "STAMBP", "STARD3", "STX10", "STX12", "STX3", "STX5", "STX7", "SV2A", "SYNCRIP", "TAF15", "TAP1", "TAX1BP1", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TCEA1", "TDRKH", "TFRC", "THOC1", "TJP1", "TMED2", "TMED7", "TMPO", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TPBG", "TRAM1", "TRAP1", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNDC5", "UBE4B", "UBXN1", "UBXN4", "UNC119B", "USP11", "VAMP7", "VIM", "VLDLR", "XRCC6", "YTHDC2"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..12384471e59772acdabeb1f66acddeffbf82d24c --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Syntaxin [IPR045242]", "1": "Mitochondrial carrier protein [IPR002067]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ffe482b2375abdfc8c8dfe587820cf8914d1aa9c --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:32f42dd6da261cdbde7ff687b4f7216287c752a4d5ca1fe055371d80aa7d1c7f +size 176873 diff --git a/interpro_family/advanced/plot_1.png b/interpro_family/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..434bcdf38fed0742352238aa97c3728dd229087d --- /dev/null +++ b/interpro_family/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f95e631716c96ef272d9fc172eed16465a725aa2c367799f9c8085c739cc9cb1 +size 187096 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c3a92d25344d9f11ec8adbb962f440dd262bd6e0 --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Syntaxin [IPR045242]", "1": "Mitochondrial carrier protein [IPR002067]", "2": "Small GTPase [IPR001806]", "3": "Tubulin [IPR000217]", "4": "Beta tubulin [IPR002453]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..02f3265a7bf6fdaa9a6a50820f3034e140ddf32d --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1dccb49f0e193d1376ed1ab3edaa8a9b0f75f9c9b401ddf2f06ea9ab729f7c8e +size 132258 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..aefeb41d40c70bccd580c18df819975779822825 --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c92f67c844f654a5b5b4b42864ea744afdbf597aa525bd3cc9343c0eace73b70 +size 134639 diff --git a/interpro_family/basic/plot_2.png b/interpro_family/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..0617c5ec0cdcb8222824292f2064f06a9bfacfd8 --- /dev/null +++ b/interpro_family/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:496c31c6e7de674e87e5d64d72c0c06b1c0de437bbf995aa253a218e03f0ea7e +size 131894 diff --git a/interpro_family/basic/plot_3.png b/interpro_family/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..2469f9c8fa5c4c4c5d681936f76c5d25c206742d --- /dev/null +++ b/interpro_family/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:121f437590825da8612c5ea2b28919fa5a801bc18d28070b301387a331e8b5c4 +size 128397 diff --git a/interpro_family/basic/plot_4.png b/interpro_family/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..34f06edebb5b776a8d414fb138dac3dd85d338e0 --- /dev/null +++ b/interpro_family/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eb93d3aab05f71446598c3a06b4c6fa5ec5e25c8e20bcb793f4800b33634e6ac +size 131165 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..36db1d6a70c9596f35b991357bfe2da83c9e0c2f --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2e71fbf41eae3c4dd0777358d851f47aeb43b2c562f8f1de5017983f1c74a0d3 +size 171683 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f93cb4e1de87529ae710e95971cf56d60884b906 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Syntaxin [IPR045242] 5 6 2.5130174926559024 0.0119703399320483 2.674757281553398 5.815533980582524 0.7134969984167514 0.3462495636510407 1.4434464182805606 1.4295601388514203 1.142372356309129 0.3001529293380739 9.699037575871712e-06 0.0652597674910206 0.1265462710440741 1.3414362359281e-05 2.7323384312904545e-05 +P-type ATPase [IPR001757] 4 5 2.0721355443489498 0.0382528023490802 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0108675670250155 1.0 1.0 0.0153906222854723 0.0034992238505004 +Mitochondrial carrier protein [IPR002067] 5 10 2.071075299283499 0.0383517597678213 5.686893203883495 11.07766990291262 0.8032246115450145 0.31892620527414 3.2338505495684404 1.5403272908315857 1.3918146051602212 0.3274613788058813 0.0009961844667822 1.0 1.0 0.0834574734746242 0.00223229240551 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9217c0038186551f85cefdc6cb383b386b2dccd4 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 2379, + "title": "Average number of proteins per term", + "value": 1.2765868011769652 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..68a7f1179a7db91145bdd2c4a2c47b622cad6a95 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d5fbaa09988e6d9d60eeee3d082a9d3cd9845911 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,121 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Syntaxin [IPR045242] 0.8969478175254377 2.5130174926559024 0.0119703399320483 0.9999999999996388 0.4271278556077071 6 Q13190,O60499,O15400,Q86Y82,Q13277 5 +P-type ATPase [IPR001757] 0.8549868766404107 2.0721355443489498 0.0382528023490802 1.0 0.4271278556077071 5 Q9HD20,P16615,Q04656,P05023 4 +Mitochondrial carrier protein [IPR002067] 0.6928293866363731 2.071075299283499 0.0383517597678213 1.0 0.4271278556077071 10 P12235,P12236,P05141,Q9HC21,Q6NUK1 5 +Small GTPase [IPR001806] 0.537368392271954 1.840571079006153 0.0656844391783761 1.0 0.4271278556077071 29 P20339,Q9BZG1,P61026,Q15286,P61020,Q9H0U4,Q14964,Q969Q5,P62820,P61019,P51149,P11234,P51148,Q8IXI1,Q9NP72,P11233,P51151 17 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.7872440915738401 1.7799249113180204 0.075088250197995 1.0 0.4271278556077071 5 Q9UIQ6,Q9NZ08,P55786 3 +Tetraspanin/Peripherin [IPR018499] 0.9426229508196676 1.754605735994299 0.0793267696489621 1.0 0.4271278556077071 3 O60637,O43657 2 +Eukaryotic porin/Tom40 [IPR027246] 0.8307641849786709 1.7330187466283995 0.0830923368292573 1.0 0.43008727467148 4 P45880,Q9Y277,P21796 3 +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.9904949196984604 1.7125226352637617 0.0868003968870856 1.0 0.4303828270133232 2 O60830 1 +ER lumen protein retaining receptor [IPR000133] 0.9885283513602112 1.7043961568165238 0.0883071014356775 1.0 0.4303828270133232 2 O43731 1 +Tetraspanin, animals [IPR000301] 0.9832841691248788 1.6827168778386612 0.0924299128363086 1.0 0.4303828270133232 2 O60637 1 +Palmitoyl protein thioesterase [IPR002472] 0.9829564077351703 1.6813615243054152 0.0926927141958326 1.0 0.4303828270133232 2 Q9UMR5 1 +Integral membrane protein 2 [IPR040145] 0.9809898393969207 1.673228469023432 0.0942823279240949 1.0 0.4303828270133232 2 Q9Y287 1 +Porin, eukaryotic type [IPR001925] 0.9190163934426194 1.6613656741477172 0.0966400273938941 1.0 0.4303828270133232 3 P21796,P45880 2 +Amyloidogenic glycoprotein [IPR008155] 0.9760734185512968 1.6528891983559817 0.0983534158746781 1.0 0.4303828270133232 2 P05067 1 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.9150819672131104 1.645783258843623 0.0998083901999997 1.0 0.4303828270133232 3 Q9HB40,P10619 2 +SCAMP [IPR007273] 0.8094457199081546 1.6449091819472668 0.0999885411234344 1.0 0.4303828270133232 4 O15127,O14828,Q969E2 3 +Glycoside hydrolase, family 29 [IPR000933] 0.9731235660439218 1.6406814443418902 0.100863558702005 1.0 0.4303828270133232 2 P04066 1 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.9731235660439218 1.6406814443418902 0.100863558702005 1.0 0.4303828270133232 2 P04066 1 +GOLM1/CASC4 family [IPR026139] 0.9688626679777146 1.6230430710110864 0.1045801979109524 1.0 0.4317807289883066 2 Q6P4E1 1 +Mitochondrial carrier UCP-like [IPR002030] 0.964601769911504 1.6053995394061498 0.1084059057176629 1.0 0.436375041797496 2 Q9H2D1 1 +Major facilitator, sugar transporter-like [IPR005828] 0.9016393442622952 1.5924630353926568 0.1112807024041699 1.0 0.4383719956216376 3 Q7L0J3,P11166 2 +Aminopeptidase N-type [IPR034016] 0.9003278688524576 1.58725487136971 0.112454931715239 1.0 0.4390058080922774 3 P55786,Q9UIQ6 2 +Nonaspanin (TM9SF) [IPR004240] 0.8957377049180287 1.5690183333026213 0.1166436672258686 1.0 0.4411026555153331 3 Q9HD45,Q99805 2 +Haem oxygenase [IPR002051] 0.9472304162569648 1.5334320070824283 0.1251694475248768 1.0 0.4532587818723098 2 P09601 1 +Haem oxygenase-like [IPR016053] 0.9472304162569648 1.5334320070824283 0.1251694475248768 1.0 0.4532587818723098 2 P09601 1 +Major facilitator superfamily [IPR011701] 0.7703026799691324 1.4817917750425575 0.1383957082819722 1.0 0.4643771368163779 4 Q7L0J3 1 +Beta-hexosaminidase [IPR025705] 0.9324811537200977 1.4723148948609663 0.1409358629181012 1.0 0.4660734062048788 2 P06865 1 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.8711475409835948 1.4711440083288354 0.1412521756509952 1.0 0.4660734062048788 3 P12235,P12236 2 +Transmembrane emp24 domain-containing protein [IPR015720] 0.6637308675685454 1.448544943202945 0.1474647062054384 1.0 0.4726596812260601 6 Q9Y3B3,Q15363 2 +Nucleosome assembly protein (NAP) [IPR002164] 0.8573770491803167 1.416239889894714 0.1567052804122584 1.0 0.48387246958703 3 Q99733,P55209 2 +Mpv17/PMP22 [IPR007248] 0.9137987545067194 1.3949512380556106 0.163030544456544 1.0 0.4921950066778152 2 Q567V2 1 +Chloride channel, voltage gated [IPR001807] 0.9121599475581778 1.388170462151852 0.1650851444468637 1.0 0.4924800583927464 2 P51790 1 +Importin beta family [IPR040122] 0.7478347053966223 1.3875400393141517 0.1652771507747839 1.0 0.4924800583927464 4 Q92973 1 +E3 ubiquitin-protein ligase, SMURF1 type [IPR024928] 0.9065880039331372 1.3651251415729573 0.1722137212452053 1.0 0.5002039733127559 2 Q96J02 1 +Glucose transporter GLUT [IPR045263] 0.9013438216978038 1.3434505066715507 0.1791261419587406 1.0 0.5094831578949727 2 P11166 1 +Sugar/inositol transporter [IPR003663] 0.9013438216978038 1.3434505066715507 0.1791261419587406 1.0 0.5094831578949727 2 P11166 1 +Small GTPase superfamily, SAR1-type [IPR006687] 0.8980662078007213 1.3299123899866117 0.1835471386796634 1.0 0.5132728513469085 2 Q9NR31 1 +TAF15/EWS/TLS family [IPR034870] 0.8357377049180312 1.3299109646414171 0.1835476083567542 1.0 0.5132728513469085 3 Q01844,P35637 2 +Nucleobindin [IPR040250] 0.894460832513944 1.315028913974327 0.188500185231057 1.0 0.5190300239174591 2 P80303 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.8918387413962647 1.3042105927827845 0.1921617891798368 1.0 0.5230582339345902 2 O96005 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.8918387413962647 1.3042105927827845 0.1921617891798368 1.0 0.5230582339345902 2 O96005 1 +Peptidase C13, legumain [IPR001096] 0.8879056047197682 1.287993426110709 0.197748251567617 1.0 0.5279944898758259 2 Q99538 1 +CD36 family [IPR002159] 0.8829891838741438 1.267740946186702 0.2048904772125439 1.0 0.5375067054979743 2 Q14108 1 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 0.7192522138405971 1.2672254972143278 0.205074671315198 1.0 0.5375067054979743 4 Q14344,P04899,P08754 3 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.88266142248444 1.2663915813972726 0.2053729234401635 1.0 0.5375067054979743 2 Q93050 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.88266142248444 1.2663915813972726 0.2053729234401635 1.0 0.5375067054979743 2 Q93050 1 +Peptidase A22B, signal peptide peptidase [IPR007369] 0.8800393313667758 1.2556004656743305 0.2092608624597294 1.0 0.5417101107635434 2 Q8TCT8 1 +Presenilin/signal peptide peptidase [IPR006639] 0.8800393313667758 1.2556004656743305 0.2092608624597294 1.0 0.5417101107635434 2 Q8TCT8 1 +Bicarbonate transporter, eukaryotic [IPR003020] 0.8698787282858071 1.213854535779189 0.2248032766875438 1.0 0.5573429821699987 2 P04920 1 +Surfeit locus 1/4 [IPR045214] 0.8669288757784395 1.20175761856967 0.2294574501169095 1.0 0.5633429038473972 2 O15260 1 +Flotillin family [IPR027705] 0.8587348410357261 1.168216184408139 0.2427195737972942 1.0 0.5769769222852267 2 O75955 1 +Calcium uptake protein 1/2/3 [IPR039800] 0.8561127499180599 1.1575033976892968 0.2470667519467486 1.0 0.5831069473028919 2 Q8IYU8 1 +Small GTPase, Ras-type [IPR020849] 0.683830764184959 1.1179743340912591 0.2635779552550801 1.0 0.6058473000500827 4 P62070,P11233,P11234 3 +Prenyltransferase subunit beta [IPR045089] 0.8433300557194494 1.1054393116803287 0.2689692775638839 1.0 0.6114429434156153 2 P49356 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.8262864634546043 1.036506443693891 0.2999659348340366 1.0 0.6438004339457809 2 Q9NVI7 1 +Histidine phosphatase superfamily, clade-2 [IPR000560] 0.7612726623902222 1.0343172005266978 0.3009878982957659 1.0 0.6438004339457809 3 P11117 1 +MICOS complex subunit MIC26/MIC27, animal [IPR033182] 0.8256309406752006 1.0338678790714186 0.3011979331574839 1.0 0.6438004339457809 2 Q9BUR5 1 +MICOS complex subunit MIC26/MIC27 [IPR019166] 0.8256309406752006 1.0338678790714186 0.3011979331574839 1.0 0.6438004339457809 2 Q9BUR5 1 +Prenylated rab acceptor PRA1 [IPR004895] 0.822681088167813 1.0220070362507083 0.3067775701891033 1.0 0.6475810465659954 2 O75915 1 +Membrane bound O-acyl transferase, MBOAT [IPR004299] 0.8171091445427718 0.9996621030933645 0.3174740578083792 1.0 0.6619375841596268 2 Q96N66 1 +Microtubule-associated protein RP/EB [IPR027328] 0.8017043592264999 0.93832606605621 0.3480768681687696 1.0 0.6881298539975446 2 Q15555 1 +Oligosaccharyl transferase, STT3 subunit [IPR003674] 0.789249426417566 0.8892731513096441 0.3738562971997001 1.0 0.7121801966226425 2 P46977 1 +SNX17/27/31 [IPR037831] 0.7843330055719415 0.8700589910013461 0.3842681671094783 1.0 0.7213987230801149 2 Q96L92 1 +G-protein alpha subunit, group I [IPR001408] 0.719016393442611 0.869900451697827 0.3843548086015129 1.0 0.7213987230801149 3 P04899,P08754 2 +Phosphatidyl serine synthase [IPR004277] 0.7823664372336916 0.8623985323937209 0.3884682478773449 1.0 0.725404993485246 2 P48651 1 +Dynamin [IPR022812] 0.7084209565966504 0.8293666526804251 0.4068969653530496 1.0 0.7443595286034921 3 O60313 1 +Ras-related protein Ral [IPR028412] 0.7725335955424651 0.8243247728644154 0.4097550462594408 1.0 0.7458489049527837 2 P11233 1 +Translation initiation factor IF2/IF5 [IPR045196] 0.7646673221894673 0.7941582365107386 0.4271033181132351 1.0 0.7622496577579793 2 P55010 1 +MRG [IPR008676] 0.7607341855129437 0.7791793554396796 0.435874069391259 1.0 0.7680528011767073 2 Q15014 1 +Copper chaperone SCO1/SenC [IPR003782] 0.7561455260570272 0.7617965017339421 0.4461814686139105 1.0 0.7747924918485352 2 O75880 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.7561455260570272 0.7617965017339421 0.4461814686139105 1.0 0.7747924918485352 2 O75880 1 +SLC12A transporter family [IPR004842] 0.7538511963290894 0.7531436749828534 0.4513635817263601 1.0 0.777168713413038 2 P55011 1 +Anoctamin [IPR007632] 0.7531956735496792 0.7506762727026541 0.452847506009804 1.0 0.7773229351056562 2 Q4KMQ2 1 +Ergosterol biosynthesis ERG4/ERG24 [IPR001171] 0.752540150770258 0.7482110418841568 0.454332871821969 1.0 0.7781554370514502 2 Q14739 1 +Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129] 0.7505735824319997 0.7408285047144036 0.4587974295586383 1.0 0.7829835616355815 2 Q99735 1 +HnRNP R/Q splicing factor [IPR006535] 0.7486070140937364 0.7334659677409536 0.4632742772700924 1.0 0.7850435502708225 2 O60506 1 +Cohesin subunit Scc3/SA [IPR039662] 0.7482792527040283 0.732240846970803 0.4640215769376405 1.0 0.7850435502708225 2 Q8WVM7 1 +Synaptobrevin [IPR001388] 0.7371353654539703 0.6909346529461495 0.4896066079734038 1.0 0.8021860333117959 2 P51809 1 +Tricarboxylate/iron carrier [IPR004686] 0.6692015468664179 0.6827915852175189 0.494738547666931 1.0 0.8089230274224254 3 Q6P4A7 1 +Phosphatidylinositol transfer protein [IPR001666] 0.7181252048508642 0.6221702672824113 0.5338299145628191 1.0 0.8376134437557421 2 Q00169 1 +Tubulin [IPR000217] 0.4886773875943626 0.6033890978648769 0.5462498731287617 1.0 0.8422089748368918 6 P04350,Q9BVA1,Q9BUF5,P07437,P68371 5 +Beta tubulin [IPR002453] 0.4886773875943626 0.6033890978648769 0.5462498731287617 1.0 0.8422089748368918 6 P04350,Q9BVA1,Q9BUF5,P07437,P68371 5 +Bcl2-like [IPR002475] 0.6377333427015313 0.5703863847023519 0.5684156620619059 1.0 0.8545112982172515 3 Q9BXK5 1 +Bcl-2 family [IPR026298] 0.6377333427015313 0.5703863847023519 0.5684156620619059 1.0 0.8545112982172515 3 Q9BXK5 1 +Tropomodulin [IPR004934] 0.6758439855784932 0.4784965085097144 0.6322968587492648 1.0 0.8854122571282792 2 P28289 1 +Oxysterol-binding protein [IPR000648] 0.5234503115775623 0.4722012286535635 0.6367831628344343 1.0 0.8880399006003072 4 Q9BZF1,P22059,Q96SU4 3 +Translin family [IPR002848] 0.670272041953454 0.4606738725360189 0.6450326028762563 1.0 0.8916516921804845 2 Q15631 1 +Cytoplasmic FMR1-interacting [IPR008081] 0.6627335299901636 0.437022087440084 0.6620953297925762 1.0 0.9007917700422932 2 Q7L576 1 +Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015] 0.6604392002622276 0.4299321088749138 0.6672450277628266 1.0 0.9029442099247807 2 P09960 1 +Clathrin light chain [IPR000996] 0.6512618813503703 0.4020957865995969 0.687613533502075 1.0 0.915094449758895 2 P09497 1 +YTH domain containing protein [IPR045168] 0.6220911176663405 0.3195678759777943 0.7492959295837882 1.0 0.9454745674274628 2 Q96MU7 1 +Small GTPase superfamily, ARF type [IPR024156] 0.5255820489673649 0.2322155262473546 0.816370619128487 1.0 0.9523640092588864 3 P40616 1 +Peptidase M3A/M3B [IPR045090] 0.512131147540986 0.2005450461953376 0.8410543317107515 1.0 0.9527282060264836 3 Q99797,Q9BYT8 2 +Small GTPase Rho [IPR003578] 0.4019028871391052 0.1504127056891489 0.8804390176188273 1.0 0.9556995787388692 5 Q8IXI2,P63000,P61586,Q8IXI1 4 +Ras GTPase GNL1-like [IPR043358] 0.5440839069157553 0.1499155394625199 0.8808312515541716 1.0 0.9556995787388692 2 Q9H089 1 +Ribosomal protein L2 [IPR002171] 0.5417895771878007 0.1461307869589483 0.8838181428052354 1.0 0.9556995787388692 2 P62917 1 +Sorting nexin-5/6/32 [IPR014637] 0.5404785316289654 0.1439992198351969 0.8855010856973997 1.0 0.9556995787388692 2 Q9Y5X3 1 +Mitochondrial Rho GTPase [IPR021181] 0.5257292690920903 0.1215676481070349 0.9032414364766012 1.0 0.9651895581943571 2 Q8IXI1 1 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.4675409836065478 0.1121725322895557 0.9106866077506526 1.0 0.9651895581943571 3 Q9ULX6,O43823 2 +Ras GTPase-activating protein-binding protein [IPR039539] 0.5050803015404672 0.0948262444991488 0.9244528407022188 1.0 0.968416251884887 2 Q13283 1 +Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309] 0.4988528351360104 0.0877881972475527 0.930045018777138 1.0 0.9697447956886578 2 O95478 1 +Chaperone DnaJ [IPR012724] 0.4981973123565928 0.0870741191955979 0.9306125971236678 1.0 0.9697447956886578 2 O60884 1 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.4981973123565928 0.0870741191955979 0.9306125971236678 1.0 0.9697447956886578 2 O60884 1 +Calponin/LIMCH1 [IPR001997] 0.496230744018349 0.0849620993574846 0.9322915220506408 1.0 0.9708891963321148 2 Q15417 1 +Tight junction protein ZO [IPR005417] 0.4749262536873037 0.0648778890063789 0.9482712255137384 1.0 0.9774424807180172 2 Q07157 1 +Ribosomal protein S5 [IPR000851] 0.470993117010804 0.0617030289223289 0.9507993278366698 1.0 0.9777231307989254 2 P82675 1 +Constitutive coactivator of PPAR-gamma [IPR026784] 0.4647656506063522 0.0569945771228815 0.9545495149501352 1.0 0.9777231307989254 2 Q96EK7 1 +Tumour protein D52 [IPR007327] 0.4591937069813134 0.0531007394556787 0.9576516422854336 1.0 0.9779262509998076 2 O43399 1 +Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081] 0.4249180327868812 0.0520423462795195 0.9584949516597194 1.0 0.9779262509998076 3 P39687,Q92688 2 +Peptidase, FtsH [IPR005936] 0.4568993772533467 0.0515819704215391 0.9588617857321464 1.0 0.9779262509998076 2 Q9Y4W6 1 +Glutathione Transferase family [IPR040079] 0.3257711409119249 0.0500199644699235 0.9601064788881184 1.0 0.9779262509998076 9 Q13505 1 +AP complex subunit beta [IPR026739] 0.4226229508196651 0.0494557888263456 0.9605560694624244 1.0 0.9779262509998076 3 Q10567,O00203 2 +Ubiquitin conjugation factor E4 [IPR045132] 0.4480498197312232 0.0461661326875103 0.9631778358798828 1.0 0.9779262509998076 2 O95155 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.4165274056803102 0.0428927525543176 0.965787026059178 1.0 0.9781214708364344 3 Q99436 1 +Heat shock protein Hsp90 family [IPR001404] 0.3666775992128534 0.0392255161929729 0.9687105903078506 1.0 0.9802477645012236 4 P14625,Q12931,P08238 3 +CTP synthase [IPR004468] 0.4313339888561022 0.03770559103017 0.9699224181710306 1.0 0.9810567316449328 2 Q9NRF8 1 +AP-1/2/4 complex subunit beta [IPR016342] 0.4224844313339796 0.0340657027700121 0.9728247578269504 1.0 0.9823217737140556 2 Q10567 1 +Molecular chaperone regulator BAG [IPR039773] 0.4009836065573725 0.0281034645787204 0.9775796308319802 1.0 0.9858677158750662 3 O95429,Q9UL15 2 +Ribosomal protein L14P [IPR000218] 0.3985578498852735 0.026651524504545 0.9787376772237208 1.0 0.9866173449640812 2 Q6P1L8 1 +Vacuolar protein sorting-associated protein 33 [IPR027121] 0.3700426089806563 0.0213753935787654 0.9829462021601892 1.0 0.98875715652238 2 Q96AX1 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5db1aa6882856d78336ecde109e71a3e584ff776 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "14kDa phosphohistidine phosphatase [IPR028441]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5'-deoxynucleotidase YfbR/HDDC2 [IPR039356]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABI family [IPR028457]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "ALG11 mannosyltransferase [IPR038013]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Abl interactor 1 [IPR028456]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acid sphingomyelinase-like phosphodiesterase, predicted [IPR017064]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-histidine N-methyltransferase SETD3 [IPR025785]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 2/3 complex subunit 5 [IPR006789]", "Actin-related protein 3 [IPR015623]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenomatous polyposis coli (APC) family [IPR026818]", "Adenomatous polyposis coli [IPR026836]", "Adenosine kinase [IPR001805]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl cyclase-associated protein CAP2 [IPR028418]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Anion exchange protein 2 [IPR002978]", "Anion exchange protein [IPR001717]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Ankyrin repeat and SAM domain-containing protein 1A [IPR033637]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-10 [IPR031291]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAX [IPR026304]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arv1 protein [IPR007290]", "Arylesterase [IPR002640]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "B-cell lymphoma/leukemia 10/E10 [IPR033238]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BBP/SF1 family [IPR031150]", "BCP1 family [IPR025602]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "BTB-kelch protein [IPR017096]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bromodomain-containing protein 8 [IPR038002]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 4 [IPR039780]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD34/Podocalyxin [IPR013836]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDC50/LEM3 family [IPR005045]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMM domain-containing protein 4 [IPR037356]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF complex subunit CPSF4-like [IPR045348]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cancer susceptibility candidate 4 [IPR026141]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carboxymethylenebutenolidase homolog [IPR042946]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-2 [IPR035702]", "Caspase-3/7 [IPR015471]", "Cat eye syndrome critical region protein 2 [IPR029614]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cation/H+ exchanger, CPA1 family [IPR018422]", "Cationic amino acid transport permease [IPR004755]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle control protein 50A [IPR030351]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Cellular repressor of E1A-stimulated genes (CREG) [IPR014631]", "Centrin 2 [IPR037629]", "Centromere protein Cenp-M [IPR020987]", "Centromere protein I [IPR012485]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 290kDa [IPR026201]", "Centrosomal protein of 44kDa [IPR033603]", "Centrosomal protein of 55kDa [IPR038926]", "Ceramide glucosyltransferase [IPR025993]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin complexes subunit BAP18 [IPR037931]", "Chromatin modification-related protein Eaf6 [IPR015418]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Copper homeostasis protein CutC [IPR005627]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Core-binding factor, beta subunit [IPR003417]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic protein NCK [IPR017304]", "Cytoplasmic protein NCK1 [IPR028526]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad4 [IPR004583]", "DNA repair protein Rad4, subgroup [IPR018026]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair protein XPF [IPR006167]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyribonuclease II [IPR004947]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Disks large 1-like [IPR016313]", "Divalent ion tolerance protein, CutA [IPR004323]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [IPR039485]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dymeclin [IPR019142]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase CBX4 [IPR043531]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongator complex protein 4 [IPR008728]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosulphine [IPR006760]", "Endothelial protein C receptor [IPR015669]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Est1/Ebs1-like [IPR045153]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "F-box-like/WD repeat-containing protein Ebi-like [IPR045183]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM91 [IPR039199]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FUN14 [IPR007014]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Forkhead box protein C1 [IPR033067]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GDP-mannose 4,6-dehydratase [IPR006368]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf1 [IPR005339]", "GINS complex, subunit Psf3 [IPR010492]", "GOLM1/CASC4 family [IPR026139]", "GPCR, family 2, ADGRE2/ADGRE5 [IPR003056]", "GPCR, family 2, secretin-like [IPR000832]", "GPI mannosyltransferase [IPR005599]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "Galactokinase [IPR000705]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit beta [IPR026873]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose transporter, type 4 (GLUT4) [IPR002441]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, alpha class [IPR003080]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent [IPR006168]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic [IPR017751]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycoside hydrolase, family 79 [IPR005199]", "Glycosyl transferase, family 13 [IPR004139]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi membrane protein 1 [IPR026143]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Gtr1/RagA G protein [IPR006762]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "H/ACA ribonucleoprotein complex, subunit Nop10 [IPR007264]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAUS augmin-like complex subunit 2 [IPR028346]", "HAUS augmin-like complex subunit 2, metazoa [IPR026242]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone chaperone ASF1-like [IPR006818]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "Histone-lysine N-methyltransferase, SET [IPR017155]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Huntingtin-interacting protein 1 [IPR030554]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Immunity-related GTPase family Q protein [IPR040070]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 10 [IPR026164]", "Integrator complex subunit 12 [IPR039053]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 2 [IPR029321]", "Integrator complex subunit 2, metazoa [IPR026236]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 9 [IPR027074]", "Integrin alpha chain [IPR000413]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon gamma receptor alpha subunit [IPR008355]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intracellular lipid binding protein [IPR031259]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Isoamyl acetate-hydrolyzing esterase Iah1-like [IPR045136]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "Janus [IPR007702]", "Jlp2/Ccd25 [IPR039730]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KRR1 interacting protein 1 [IPR018034]", "Kelch-like ECH-associated protein 1 [IPR030563]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine zipper putative tumor suppressor [IPR045329]", "Leucine zipper putative tumour suppressor 2 [IPR028597]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte elastase inhibitor (serpin B1) [IPR015557]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lupus La protein [IPR002344]", "LysM and putative peptidoglycan-binding domain-containing protein 1-4 [IPR045030]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosomal-associated transmembrane protein 4/5 [IPR004687]", "Lysosomal-associated transmembrane protein, 4A/5 [IPR018396]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase phosphoprotein 6 [IPR019324]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MORF4 family-associated protein 1 [IPR029254]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Magnesium transporter protein 1 [IPR006844]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannosyltransferase ALG2 [IPR027054]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membralin [IPR019144]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane cofactor protein CD46 [IPR017341]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthiotransferase [IPR005839]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microtubule associated protein 1 [IPR026074]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitogen-activated protein (MAP) kinase kinase kinase kinase [IPR021160]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multidrug resistance protein 1 [IPR030258]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Multivesicular body subunit 12 [IPR018798]", "Multivesicular body subunit 12A [IPR040335]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase Ard1-like [IPR045047]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-plastoquinone oxidoreductase, chain 5 subgroup [IPR018393]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain 5-like [IPR003945]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B/Dorsal [IPR000451]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Na+/H+ exchanger [IPR004709]", "Na+/H+ exchanger, isoform 6/7/9 [IPR002090]", "Nck-associated protein 1 [IPR019137]", "Nectin-2 [IPR033318]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neuropilin [IPR014648]", "Neuropilin-1 [IPR027146]", "Next to BRCA1 gene 1 protein [IPR033513]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar and spindle-associated protein 1 [IPR026756]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "NudC domain-containing protein 1 [IPR037895]", "NudC family [IPR037898]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ORC ubiquitin ligase 1 [IPR039209]", "Occludin [IPR002958]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IB [IPR027256]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Palmitoyltransferase ZDHHC13 [IPR030290]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Paxillin [IPR001904]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyase [IPR000720]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylinositol N-acetylglucosaminyltransferase subunit PIG-A/GPI3 [IPR039507]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylase kinase alpha/beta subunit [IPR008734]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphoserine phosphatase [IPR004469]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Podocalyxin [IPR017403]", "Polo kinase kinase [IPR022165]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polycomb protein EED [IPR037352]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Pre-rRNA-processing protein TSR2 [IPR019398]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline racemase family [IPR008794]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase 3 [IPR039839]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM234 [IPR045232]", "Protein FAM3C [IPR039219]", "Protein FRG1 [IPR010414]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein TFG [IPR033512]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF3512 [IPR021900]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF4726 [IPR031714]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein virilizer [IPR026736]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Proto-oncogene c-Rel [IPR030505]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA methyltransferase [IPR003750]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAD3/XPD family [IPR001945]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding protein Nova-2 [IPR033087]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab-like protein 6 [IPR040385]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab35 [IPR041815]", "Rab39 [IPR041818]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab9 [IPR041824]", "Rabaptin [IPR003914]", "Rabaptin-5 [IPR029880]", "Rad21/Rec8-like protein [IPR039781]", "RagC/D [IPR039400]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "Ral GTPase-activating protein subunit beta [IPR039930]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "Root UVB sensitive family [IPR006968]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SERRATE/Ars2 [IPR039727]", "SH3 and PX domain-containing protein 2B [IPR030512]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sdc1/DPY30 [IPR037856]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "SecY/SEC61-alpha family [IPR002208]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Ser/Thr protein kinase, TGFB receptor [IPR000333]", "Serine hydroxymethyltransferase [IPR001085]", "Serine incorporator 1/3 [IPR029557]", "Serine incorporator/TMS membrane protein [IPR005016]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase RAC alpha [IPR039027]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase TOUSLED-like 2 [IPR027086]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sialidase family [IPR026856]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Sm-like protein Lsm6/SmF [IPR016487]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small acidic protein [IPR026714]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smooth muscle protein/calponin [IPR003096]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 1/Shy1 [IPR002994]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntaxin-3 [IPR031186]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TB2/DP1/HVA22-related protein [IPR004345]", "TCF25/Rqc1 [IPR006994]", "TE2IP/Rap1 [IPR039595]", "TEL2-interacting protein 1 [IPR016441]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM206 protein [IPR029366]", "TMEM33/Pom33 family [IPR005344]", "TMEM9/TMEM9B [IPR008853]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TREX component Tex1/THOC3 [IPR040132]", "Tankyrase 1-binding protein-like [IPR040006]", "Target of Myb protein 1 [IPR014645]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Teneurin-3/4 [IPR027691]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "The WD repeat Cdc20/Fizzy family [IPR033010]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor STAT [IPR001217]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulator TACO1-like [IPR002876]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Translocon-associated protein subunit gamma [IPR009779]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tuberin [IPR003913]", "Tuberin/Ral GTPase-activating protein subunit alpha [IPR027107]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Type 1 protein exporter [IPR039421]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine protein kinase, EGF/ERB/XmrK receptor [IPR016245]", "Tyrosine-protein kinase, insulin-like receptor [IPR016246]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronic acid decarboxylase [IPR044516]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised protein family UPF0687 [IPR026794]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-IXb [IPR028557]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Vacuole morphology and inheritance protein 14 [IPR026825]", "Valine-tRNA ligase [IPR002303]", "Vang-like protein [IPR009539]", "Very low-density lipoprotein receptor [IPR032931]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat HIR1 [IPR031120]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 73 [IPR042795]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YIP1 family member 3 [IPR026637]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor Gle2/RAE1 [IPR037631]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7 [IPR028590]", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit [IPR028884]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA pseudouridine synthase B family [IPR004802]"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSL1", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANKLE2", "ANKS1A", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEX1", "API5", "APLP2", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFIP1", "ARHGDIA", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMC6", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASF1B", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATXN2L", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ2A", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BDH2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPNT1", "BRAT1", "BRCA1", "BRD7", "BRD8", "BRD9", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BUB1B", "BUD31", "BYSL", "C11orf58", "C14orf2", "C16orf58", "C17orf75", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C20orf27", "C2CD5", "C5orf15", "C5orf24", "C8orf33", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASP2", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX3", "CBX4", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC25", "CCDC47", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD46", "CD47", "CDC123", "CDC20", "CDC37", "CDC40", "CDC42", "CDC45", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK5RAP3", "CDKAL1", "CDS2", "CDV3", "CDYL", "CEBPZ", "CECR2", "CELF2", "CENPI", "CENPM", "CEP170", "CEP290", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHERP", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CIAPIN1", "CIP2A", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT4", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG7", "COIL", "COLGALT1", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF2", "CPSF4", "CPSF6", "CPSF7", "CPT2", "CPVL", "CREG1", "CRNKL1", "CRTAP", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWF19L1", "CXorf56", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDX54", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX29", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIMT1", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPH2", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUT", "DYM", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EGFR", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM120B", "FAM136A", "FAM162A", "FAM177A1", "FAM213A", "FAM234B", "FAM3C", "FAM49B", "FAM50A", "FAM91A1", "FAM98A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTB", "FOXC1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GCAT", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GM2A", "GMDS", "GMFB", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLM2", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR89B", "GPS1", "GPX8", "GRPEL1", "GRSF1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDHD2", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HELZ", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HYOU1", "IAH1", "IARS", "IARS2", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INTS10", "INTS12", "INTS13", "INTS14", "INTS2", "INTS3", "INTS9", "IPO4", "IPO5", "IRGQ", "IRS4", "ISCU", "IST1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "IVD", "JPT2", "JUP", "KARS", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA2013", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF5B", "KIFBP", "KLC1", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L3HYPDH", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMF2", "LNPEP", "LONP1", "LRPAP1", "LRPPRC", "LRRC47", "LSG1", "LSM12", "LSM2", "LSM3", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAP1B", "MAP1S", "MAP4", "MAP4K5", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED16", "MED17", "MED24", "MED4", "MEPCE", "MESD", "METAP2", "METTL1", "MFN1", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MMAB", "MMGT1", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17", "MPV17L2", "MRE11", "MRFAP1", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS15", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MVB12A", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NBR1", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCLN", "NCSTN", "ND1", "ND5", "NDC1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NELFCD", "NELFE", "NES", "NEU1", "NF1", "NFS1", "NHP2", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRP1", "NSA2", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUSAP1", "NUTF2", "NXF1", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAK2", "PAM", "PANK4", "PAPSS1", "PARG", "PARK7", "PARN", "PBDC1", "PBRM1", "PC", "PCBD1", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PHPT1", "PI4K2A", "PI4KB", "PICALM", "PIGA", "PIGK", "PIGS", "PIGT", "PIGU", 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"PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPH", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTB", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM5", "RBM8A", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL5", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETREG3", "REXO4", "RFC1", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOX2", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF219", "RNF40", "RNMT", "RNPEP", "ROCK2", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAGC", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCB", "RTFDC1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERINC1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMG5", "SMPD4", "SMPDL3A", "SMS", "SMU1", "SMYD3", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPOUT1", "SPPL2A", "SPR", "SPTBN1", "SQLE", "SRFBP1", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SSB", "SSBP1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STARD3", "STAT1", "STAT3", "STIP1", "STMN1", "STOML2", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX3", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF1", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARS", "TARS2", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TECR", "TENM3", "TERF2IP", "TES", "TEX10", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TLK2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", 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"UBAP2L", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBR4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRQ", "URB1", "UROD", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "UXS1", "VAC14", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VLDLR", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "WAPL", "WARS", "WBP11", "WBP2", "WDR12", "WDR18", "WDR33", "WDR4", "WDR41", "WDR46", "WDR73", "WDR82", "WDR91", "WFS1", "WIPI2", "XAB2", "XPC", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YIF1A", "YIPF3", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H14", "ZC3H7B", "ZCCHC3", "ZDHHC13", "ZFYVE16", "ZMPSTE24", "ZMYND8", 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a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3e7af5a4b43970ea7a5aa1b5057fb716c0f3b338 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,14 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Glycoside hydrolase superfamily [IPR017853] 12 17 3.602541880184484 0.0003151206104803 7.094660194174757 15.565533980582524 0.5992585613623983 0.1928722204186086 2.565315823223627 1.245604487832095 1.9386029676344616 0.2695693578719223 4.2231453558905534e-12 0.0068317681715133 3.456655046744048e-09 7.574319120455477e-12 4.150575773415949e-11 +Immunoglobulin-like domain superfamily [IPR036179] 11 16 3.110194766819125 0.001869640181781 4.480582524271845 12.427184466019416 0.4075261998509777 0.4433674298264088 2.6479725987944898 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0.299664609287172 2.8122138641683824e-06 0.1093006244161378 0.0015052123544451 1.0946556618648063e-06 9.47697315695096e-07 +Growth factor receptor cysteine-rich domain superfamily [IPR009030] 6 8 2.544123209347627 0.0109552434317519 1.2203856749311297 2.6942148760330578 -0.1665405502801967 0.33863481843602 1.1834128472166114 1.8370669604533123 1.6157864534436548 0.3193113842408702 0.0047059421450486 0.2220822570468345 0.3955810682553247 0.0015231541907095 0.012256850099211 +Glycosyl hydrolase, all-beta [IPR013780] 5 8 2.5062804031270742 0.0122008819270187 3.628640776699029 7.919902912621359 0.108448733903935 0.2677010542317815 1.6191976609214136 0.9906808437954988 1.5895506376095985 0.2857304479214345 5.737823424793828e-06 0.0017062060788896 5.369271916582234e-06 8.796898694645245e-06 1.6279070379868977e-05 +SNARE [IPR010989] 4 5 2.3469218634237228 0.0189292239405007 2.4854368932038833 5.364077669902913 0.7966086592831925 0.3585374753437345 1.5079985943563208 1.7302199405020957 1.098385457365192 0.3157194502762394 0.0003209345081955 0.0742352733278267 0.1432798584585485 2.812625820330817e-05 0.0007388687073799 +LDL receptor-like superfamily [IPR036055] 4 7 2.328348255408172 0.0198936188923386 1.1577669902912622 2.2135922330097086 -0.4618571585064355 0.3784040995227052 0.963842866820141 1.321226889644718 1.4657719604998898 0.3224476960770873 0.0007725705229972 0.0875404472016038 0.014058804472369 7.054294597105141e-05 0.000200465132953 +Galactose-binding-like domain superfamily [IPR008979] 5 12 2.158516208348776 0.0308877196143015 3.0266990291262137 10.45388349514563 0.2272915730277323 0.4946686484554474 2.0113188873716883 2.8129916124420524 1.0072294248002038 0.3052099564304033 0.0164354132133173 0.2183067054048652 0.0128487417044244 0.0345596402774107 0.0359869143678365 +P-type ATPase, transmembrane domain superfamily [IPR023298] 4 5 2.0721355443489498 0.0382528023490802 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0127437063312673 1.0 1.0 0.0173886328284286 0.0042957165481444 +P-type ATPase, cytoplasmic domain N [IPR023299] 4 5 2.0721355443489498 0.0382528023490802 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0108675670250155 1.0 1.0 0.0153906222854723 0.0034992238505004 +P-type ATPase, A domain superfamily [IPR008250] 4 5 2.0721355443489498 0.0382528023490802 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0108675670250155 1.0 1.0 0.0153906222854723 0.0034992238505004 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d57ad46386f8a5fc904a1c8eab702fb3c70dd57f --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 953, + "title": "Average number of proteins per term", + "value": 4.732423924449108 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..273bdd1c4f6d3d7da2065b1e57c7b537320717bf --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8d027e46b0c87913cc9f6b4000aa4edca3e7e518 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,129 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Glycoside hydrolase superfamily [IPR017853] 0.8655030806351522 3.602541880184484 0.0003151206104803 0.2594464031750235 0.3003099417877602 17 P54802,P04062,O00462,P16278,P06865,P04066,P06280,P07686,P08236,Q9BTY2,P10253,Q9Y251 12 +Immunoglobulin-like domain superfamily [IPR036179] 0.7968470915361385 3.1101947668191254 0.001869640181781 0.8319400980520184 0.4942128348333225 16 Q9Y624,P35613,P01889,P10321,P10586,P04439,Q08722,Q7KYR7,P43121,Q96J84,Q5ZPR3 11 +Immunoglobulin-like fold [IPR013783] 0.7035960251921849 3.105216556204735 0.0019013975935375 0.8369595240029031 0.4942128348333225 37 Q9Y624,O00462,Q15375,O15031,P35613,P10321,P01889,P10586,Q96J84,P04439,Q08722,P43121,P08236,P15260,Q92673,Q8IZA0,Q14596,Q5ZPR3 18 +Mitochondrial carrier domain superfamily [IPR023395] 0.7009736508517049 2.9277210348251104 0.0034145625858088 0.9615980273718548 0.4942128348333225 20 P12235,P12236,Q70HW3,P05141,Q9HC21,Q6NUK1,Q9UBX3,Q9Y619,Q9H2D1,Q9BSK2,Q9NZJ7 11 +Six-bladed beta-propeller, TolB-like [IPR011042] 0.7873713080997448 2.686817499065932 0.0072136354476588 0.9989917205175648 0.4942128348333225 12 P98164,P98155,Q07954,Q92673,P14543,P01130,P19021 7 +Growth factor receptor cysteine-rich domain superfamily [IPR009030] 0.8474973582055407 2.544123209347627 0.0109552434317519 0.9999724072195758 0.4942128348333225 8 Q15375,P98164,P48960,Q07954,P14543,P01130 6 +Glycosyl hydrolase, all-beta [IPR013780] 0.8392340205496039 2.5062804031270742 0.0122008819270187 0.9999916975116072 0.4942128348333225 8 P04066,P06280,Q9BTY2,O00754,P10253 5 +SNARE [IPR010989] 0.9206036745406824 2.3469218634237228 0.0189292239405007 0.9999999876853156 0.4942128348333225 5 O60499,Q13190,O15400,Q13277 4 +LDL receptor-like superfamily [IPR036055] 0.8301197884689442 2.3283482554081716 0.0198936188923386 0.9999999951763526 0.4942128348333225 7 P98155,P01130,Q07954,Q92673 4 +Galactose-binding-like domain superfamily [IPR008979] 0.686968210923493 2.158516208348776 0.0308877196143015 0.9999999999998966 0.4942128348333225 12 O00462,Q15375,P16278,P08236,Q08431 5 +Zinc finger, ZZ-type superfamily [IPR043145] 0.9185212057686012 2.0890419933557887 0.0367039432017171 0.9999999999999996 0.4942128348333225 4 Q13501 1 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.8549868766404107 2.0721355443489498 0.0382528023490802 1.0 0.4942128348333225 5 Q9HD20,P16615,Q04656,P05023 4 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.8549868766404107 2.0721355443489498 0.0382528023490802 1.0 0.4942128348333225 5 Q9HD20,P16615,Q04656,P05023 4 +P-type ATPase, A domain superfamily [IPR008250] 0.8549868766404107 2.0721355443489498 0.0382528023490802 1.0 0.4942128348333225 5 Q9HD20,P16615,Q04656,P05023 4 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.8943916038045201 1.9923005301448091 0.0463380935769188 1.0 0.4942128348333225 4 Q9UNN8,P10321,P04439 3 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.8943916038045201 1.9923005301448091 0.0463380935769188 1.0 0.4942128348333225 4 Q9UNN8,P10321,P04439 3 +EF-hand domain pair [IPR011992] 0.528239653015908 1.95087583878809 0.0510718174392965 1.0 0.4942128348333225 47 O95302,Q02818,Q9Y680,O75071,P80303,Q9H223,Q9H4M9,O95202,Q6NUK1,Q9BRK5,Q8IYU8,P41208,P0DP25,Q9BPX6,Q14257,Q9NWM8,O43852 17 +Fibronectin type III superfamily [IPR036116] 0.7047938229965358 1.8651415253864003 0.0621615693032895 1.0 0.5047834519749154 8 Q15375,Q92673,P15260 3 +C-type lectin fold [IPR016187] 0.9613114754098352 1.8280744254082208 0.0675383826023681 1.0 0.5080924101860803 3 Q8IX05,Q9UBG0 2 +C-type lectin-like/link domain superfamily [IPR016186] 0.9613114754098352 1.8280744254082208 0.0675383826023681 1.0 0.5080924101860803 3 Q8IX05,Q9UBG0 2 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.7872440915738401 1.7799249113180204 0.075088250197995 1.0 0.5080924101860803 5 Q9UIQ6,Q9NZ08,P55786 3 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.7872440915738401 1.7799249113180204 0.075088250197995 1.0 0.5080924101860803 5 Q9UIQ6,Q9NZ08,P55786 3 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.9426229508196676 1.754605735994299 0.0793267696489621 1.0 0.5107206907468824 3 O60637,O43657 2 +MFS transporter superfamily [IPR036259] 0.6211325154964683 1.7379179266317286 0.0822252764556057 1.0 0.5121613624979887 11 Q8NHS3,Q7L0J3,Q16625,P11166 4 +Porin domain superfamily [IPR023614] 0.8307641849786709 1.7330187466283995 0.0830923368292573 1.0 0.5142012792096248 4 P45880,Q9Y277,P21796 3 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.7222736573435307 1.726766028539802 0.0842096918684935 1.0 0.5177537829075767 6 O43169,O15173 2 +Beta-hexosaminidase-like, domain 2 [IPR029018] 0.9327868852459013 1.715811307348606 0.0861965839405785 1.0 0.5181266128980576 3 P54802,P06865 2 +Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669] 0.9760734185512968 1.6528891983559817 0.0983534158746781 1.0 0.5181266128980576 2 P05067 1 +Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880] 0.9760734185512968 1.6528891983559817 0.0983534158746781 1.0 0.5181266128980576 2 P05067 1 +Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454] 0.9760734185512968 1.6528891983559817 0.0983534158746781 1.0 0.5181266128980576 2 P05067 1 +E2 domain superfamily [IPR036176] 0.9760734185512968 1.6528891983559817 0.0983534158746781 1.0 0.5181266128980576 2 P05067 1 +Ricin B-like lectins [IPR035992] 0.8081338143653514 1.639468934865753 0.1011156352681434 1.0 0.5181266128980576 4 Q10472,Q10471,Q9UBG0 3 +Haem oxygenase-like, multi-helical [IPR016084] 0.9472304162569648 1.5334320070824283 0.1251694475248768 1.0 0.5621676723861043 2 P09601 1 +Kringle-like fold [IPR013806] 0.8725266144423544 1.476639591835371 0.139772272903724 1.0 0.5668211747968044 3 Q9UBG0 1 +Fibronectin type II domain superfamily [IPR036943] 0.8725266144423544 1.476639591835371 0.139772272903724 1.0 0.5668211747968044 3 Q9UBG0 1 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.7103773513669334 1.4391038650243229 0.1501210971348476 1.0 0.5768766353609267 5 P33908 1 +Sushi/SCR/CCP superfamily [IPR035976] 0.9216650278597208 1.4275133484438056 0.1534319803814448 1.0 0.5794212363889755 2 Q6UXD5 1 +Beta-Galactosidase/glucuronidase domain superfamily [IPR036156] 0.9213372664700162 1.4261561761815276 0.1538232663236209 1.0 0.5794212363889755 2 O00462 1 +NAP-like superfamily [IPR037231] 0.8573770491803167 1.416239889894714 0.1567052804122584 1.0 0.5848313692368464 3 Q99733,P55209 2 +Chloride channel, core [IPR014743] 0.9121599475581778 1.388170462151852 0.1650851444468637 1.0 0.5918573289513849 2 P51790 1 +LEM/LEM-like domain superfamily [IPR011015] 0.6511123113148904 1.387798627019792 0.1651983730336499 1.0 0.5918573289513849 6 P42167,Q86XL3 2 +Galactose mutarotase-like domain superfamily [IPR011013] 0.6970176553708729 1.3790773415932382 0.1678709090856565 1.0 0.5991796867364443 5 P10253 1 +START-like domain superfamily [IPR023393] 0.6946500986336228 1.3684212874525914 0.1711802447044663 1.0 0.6087118403110315 5 Q9NQZ5,Q14849,Q00169 3 +Carboxypeptidase-like, regulatory domain superfamily [IPR008969] 0.8426265701788813 1.357394414166633 0.1746559221429282 1.0 0.6119508901256643 3 P16870 1 +HAD-like superfamily [IPR036412] 0.4904413448926459 1.3224522750214918 0.1860175914514907 1.0 0.6170561439844159 17 P16615,Q04656,P05023,Q9HD20,Q05D32,Q969T7,P20020 7 +HAD superfamily [IPR023214] 0.4904413448926459 1.3224522750214918 0.1860175914514907 1.0 0.6170561439844159 17 P16615,Q04656,P05023,Q9HD20,Q05D32,Q969T7,P20020 7 +GOLD domain superfamily [IPR036598] 0.8244543923661489 1.2849097300749897 0.1988238303991596 1.0 0.6294987055494987 3 Q9Y3B3 1 +G protein alpha subunit, helical insertion [IPR011025] 0.7192522138405971 1.2672254972143278 0.205074671315198 1.0 0.6407743008635532 4 Q14344,P04899,P08754 3 +Phosphotransferase/anion transporter [IPR016152] 0.8698787282858071 1.213854535779189 0.2248032766875438 1.0 0.6472432709463121 2 P04920 1 +Spermadhesin, CUB domain superfamily [IPR035914] 0.8652900688299043 1.195041956715814 0.2320706378508128 1.0 0.6506771142072404 2 Q6UXD5 1 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.4601414779421878 1.1912271442201186 0.2335644261720211 1.0 0.6506771142072404 18 Q6NUM9,P09622,Q9UHG3,O95831,Q96CU9,Q14534 6 +Guanylate-binding protein, C-terminal domain superfamily [IPR036543] 0.8607014093739762 1.1762575064809335 0.2394919908258352 1.0 0.6506771142072404 2 Q8NHH9 1 +FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156] 0.6859939673337928 1.127080316189789 0.2597085248307487 1.0 0.6725603917491944 4 P09622 1 +Mannose-6-phosphate receptor binding domain superfamily [IPR009011] 0.7823064300954818 1.1173295931784446 0.2638534267747312 1.0 0.6746436537986901 3 P11717 1 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.4319541688060737 1.0700633142924634 0.2845908106560983 1.0 0.69277496158757 19 Q86SF2,Q10471,Q68CQ7,Q9Y5P6,P26572,Q10472,Q16739 7 +Integrin domain superfamily [IPR032695] 0.8289085545722863 1.0470706994726686 0.2950669718999519 1.0 0.7012503141166129 2 P06756 1 +Receptor L-domain superfamily [IPR036941] 0.8167813831530686 0.9983501804339892 0.3181095825552704 1.0 0.7269986383097667 2 P00533 1 +Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261] 0.8085873484103585 0.965647016826301 0.3342208400689466 1.0 0.7497237216230889 2 P16435 1 +Riboflavin synthase-like beta-barrel [IPR017938] 0.8085873484103585 0.965647016826301 0.3342208400689466 1.0 0.7497237216230889 2 P16435 1 +Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330] 0.8069485414618343 0.9591291650345594 0.3374936795134367 1.0 0.7497237216230889 2 O00754 1 +Glycoside hydrolase family 38, central domain superfamily [IPR037094] 0.8069485414618343 0.9591291650345594 0.3374936795134367 1.0 0.7497237216230889 2 O00754 1 +Glycoside hydrolase families 57/38, central domain superfamily [IPR028995] 0.8069485414618343 0.9591291650345594 0.3374936795134367 1.0 0.7497237216230889 2 O00754 1 +Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291] 0.8069485414618343 0.9591291650345594 0.3374936795134367 1.0 0.7497237216230889 2 O00754 1 +EB1, C-terminal domain superfamily [IPR036133] 0.8017043592264999 0.93832606605621 0.3480768681687696 1.0 0.7548529174628115 2 Q15555 1 +Histidine phosphatase superfamily [IPR029033] 0.5550643864758715 0.92092560392211 0.3570892699355616 1.0 0.7638392382668832 6 P11117 1 +UBA-like superfamily [IPR009060] 0.4136476094106561 0.918656885481938 0.3582750676865653 1.0 0.7638392382668832 21 Q13501 1 +Translation initiation factor IF2/IF5, zinc-binding [IPR016190] 0.7646673221894673 0.7941582365107386 0.4271033181132351 1.0 0.814661697236615 2 P55010 1 +Translation initiation factor IF2/IF5, N-terminal [IPR016189] 0.7646673221894673 0.7941582365107386 0.4271033181132351 1.0 0.814661697236615 2 P55010 1 +MRG, C-terminal domain superfamily [IPR038217] 0.7607341855129437 0.7791793554396796 0.435874069391259 1.0 0.8189671012631335 2 Q15014 1 +BRO1 domain superfamily [IPR038499] 0.7594231399541105 0.7742024974779254 0.4388110516183281 1.0 0.8209555383429381 2 Q8WUM4 1 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.7558177646673331 0.760558784838333 0.4469206450679008 1.0 0.8254173929257936 2 A6NIH7 1 +NTF2-like domain superfamily [IPR032710] 0.5059093893631109 0.7519244127989163 0.4520965160250281 1.0 0.825834671184781 7 O43615,Q13555,Q13283,Q9BRJ2,P61970,Q9UBU9 6 +Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352] 0.7505735824319997 0.7408285047144036 0.4587974295586383 1.0 0.8276974376565107 2 Q99735 1 +Band 7/SPFH domain superfamily [IPR036013] 0.5158700780413292 0.7318566490009207 0.464256068340608 1.0 0.8276974376565107 6 O75955 1 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.5428141769652735 0.6872511566462826 0.4919244723105214 1.0 0.8477468754284392 5 Q03518 1 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.4888378200919425 0.6676469333615295 0.5043589913116662 1.0 0.8537373334280958 7 P04350,Q9BVA1,Q9BUK6,Q9BUF5,P07437,P68371 6 +ESCRT assembly domain [IPR037202] 0.7240249098656351 0.6432663881189687 0.5200512622131472 1.0 0.8706610694599416 2 Q9H9H4 1 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.4886773875943626 0.6033890978648769 0.5462498731287617 1.0 0.8785946790188756 6 P04350,Q9BVA1,Q9BUF5,P07437,P68371 5 +Tubulin/FtsZ, C-terminal [IPR008280] 0.4886773875943626 0.6033890978648769 0.5462498731287617 1.0 0.8785946790188756 6 P04350,Q9BVA1,Q9BUF5,P07437,P68371 5 +Tubulin, C-terminal [IPR023123] 0.4886773875943626 0.6033890978648769 0.5462498731287617 1.0 0.8785946790188756 6 P04350,Q9BVA1,Q9BUF5,P07437,P68371 5 +Ribosomal protein L37ae/L37e [IPR011331] 0.7109144542772825 0.5967058629204859 0.5507037775541572 1.0 0.8785946790188756 2 P61927 1 +WW domain superfamily [IPR036020] 0.4218166205567098 0.5925941434100399 0.5534527994997616 1.0 0.8785946790188756 11 Q96J02 1 +NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064] 0.62262483208514 0.5185370589106068 0.6040836106990053 1.0 0.9005466898651663 3 Q8TCT0 1 +Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438] 0.62262483208514 0.5185370589106068 0.6040836106990053 1.0 0.9005466898651663 3 Q8TCT0 1 +Oxysterol-binding protein superfamily [IPR037239] 0.5234503115775623 0.4722012286535635 0.6367831628344343 1.0 0.9139372803933974 4 Q9BZF1,P22059,Q96SU4 3 +Bcl-2-like superfamily [IPR036834] 0.5208020512021129 0.4625559190717712 0.6436827114788952 1.0 0.9174866724493616 4 Q9BXK5 1 +Translin, N-terminal [IPR016068] 0.670272041953454 0.4606738725360189 0.6450326028762563 1.0 0.9174866724493616 2 Q15631 1 +Translin, C-terminal [IPR016069] 0.670272041953454 0.4606738725360189 0.6450326028762563 1.0 0.9174866724493616 2 Q15631 1 +Translin superfamily [IPR036081] 0.670272041953454 0.4606738725360189 0.6450326028762563 1.0 0.9174866724493616 2 Q15631 1 +Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502] 0.6604392002622276 0.4299321088749138 0.6672450277628266 1.0 0.9189205289591582 2 P09960 1 +RmlC-like jelly roll fold [IPR014710] 0.4389634303385051 0.4297286623016736 0.6673930311258762 1.0 0.9189205289591582 7 P10644 1 +Papain-like cysteine peptidase superfamily [IPR038765] 0.3498492631559452 0.4101698389058727 0.6816813642904216 1.0 0.9267365765603022 25 P07858,Q96FW1 2 +Rab-GTPase-TBC domain superfamily [IPR035969] 0.4721128608923857 0.3941454446162957 0.6934736610156702 1.0 0.9360912166401328 5 Q4KMP7,Q9Y3P9,Q8TC07,Q66K14 4 +L27 domain superfamily [IPR036892] 0.6456899377253317 0.3856161291043782 0.6997809861419193 1.0 0.941936835866171 2 Q14168 1 +Spermidine synthase, tetramerisation domain superfamily [IPR037163] 0.6430678466076627 0.3779742632553918 0.7054497131406179 1.0 0.9468923614408576 2 P52788 1 +Alpha/Beta hydrolase fold [IPR029058] 0.3438091137263444 0.3587411430600816 0.7197887465842925 1.0 0.9580428428698754 26 Q9H3G5,Q8NCC3,P10619,Q9UMR5,Q9HB40,P50897 6 +Immunoglobulin E-set [IPR014756] 0.3642376254985722 0.3401352486716236 0.7337546779681248 1.0 0.9616507819844862 14 O15031,P61916 2 +SKP1/BTB/POZ domain superfamily [IPR011333] 0.4167792580859413 0.3301480284547398 0.7412881143502783 1.0 0.9624626334820372 7 Q08380,Q14145 2 +Zinc-binding ribosomal protein [IPR011332] 0.5537626620786594 0.3055575129485267 0.7599415738650739 1.0 0.9683117309952002 3 P61927 1 +Concanavalin A-like lectin/glucanase domain superfamily [IPR013320] 0.3164072994471852 0.2195899697826737 0.8261905037138324 1.0 0.9739560778141472 20 P27824,Q7KYR7,Q12907,O94813,O14786 5 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.3981117262245345 0.2138198248419637 0.8306875644736298 1.0 0.9739560778141472 6 Q13423 1 +Chaperone J-domain superfamily [IPR036869] 0.3362183441690402 0.207521946809986 0.8356022546405233 1.0 0.9739560778141472 15 Q9NVH1,Q99543,Q96KC8,Q9UGP8,Q9Y2G8,O60884 6 +Longin-like domain superfamily [IPR011012] 0.3467038958504674 0.2038386694228666 0.8384795733636539 1.0 0.9739560778141472 12 P51809,Q92572,O75396,O15498,Q96CW1 5 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.512131147540986 0.2005450461953376 0.8410543317107515 1.0 0.974498078284348 3 Q99797,Q9BYT8 2 +Aspartate decarboxylase-like domain superfamily [IPR009010] 0.5039344262295038 0.1823589372729405 0.8553010487363286 1.0 0.98625789472302 3 P55072,P46459 2 +Ankyrin repeat-containing domain superfamily [IPR036770] 0.3155215111323138 0.1816457619135225 0.8558607334060204 1.0 0.98625789472302 18 Q86XL3 1 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.3563108245708526 0.1736454197879365 0.8621441343979497 1.0 0.988197162223204 9 Q01844,P35637,Q92804 3 +Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151] 0.556866601114383 0.1722773557297542 0.8632194856939117 1.0 0.988197162223204 2 Q9C0B1 1 +HECT, E3 ligase catalytic domain [IPR035983] 0.3535765907678967 0.1618241485589335 0.8714443358817905 1.0 0.9898527438561934 9 Q96J02 1 +K homology domain-like, alpha/beta [IPR015946] 0.5188462799082165 0.112059976472191 0.9107758516329424 1.0 0.9972343773307476 2 P23396 1 +K homology domain superfamily, prokaryotic type [IPR009019] 0.5188462799082165 0.112059976472191 0.9107758516329424 1.0 0.9972343773307476 2 P23396 1 +CDC48 domain 2-like superfamily [IPR029067] 0.5126188135037636 0.1039733153714634 0.9171905250214794 1.0 0.9972343773307476 2 P46459 1 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.5119632907243464 0.1031502093266552 0.9178437562340332 1.0 0.9972343773307476 2 Q9BYT8 1 +Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940] 0.3965825395067981 0.0953799715960803 0.9240130238942564 1.0 0.9995282766983276 4 P42345 1 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.4981973123565928 0.0870741191955979 0.9306125971236678 1.0 1.0 2 O60884 1 +Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930] 0.4349812275634214 0.064146470412197 0.9488535999735704 1.0 1.0 3 P49356 1 +GAT domain superfamily [IPR038425] 0.4706653556211001 0.0614455777605302 0.951004355104969 1.0 1.0 2 Q9UJY4 1 +RuvA domain 2-like [IPR010994] 0.4272131147540908 0.0546929443142401 0.956383090572281 1.0 1.0 3 Q14807,Q92889 2 +Peptidase M41-like [IPR037219] 0.4568993772533467 0.0515819704215391 0.9588617857321464 1.0 1.0 2 Q9Y4W6 1 +HIV integrase-binding domain superfamily [IPR036218] 0.4513274336283125 0.0480918500367303 0.961643041420275 1.0 1.0 2 Q7Z4V5 1 +Translation elongation factor eEF-1beta-like superfamily [IPR036219] 0.4414945919370626 0.0425853019233297 0.9660321122274452 1.0 1.0 2 P29692 1 +Translation elongation factor EF1B/ribosomal protein S6 [IPR014717] 0.4414945919370626 0.0425853019233297 0.9660321122274452 1.0 1.0 2 P29692 1 +HSP90, C-terminal domain [IPR037196] 0.3666775992128534 0.0392255161929729 0.9687105903078506 1.0 1.0 4 P14625,Q12931,P08238 3 +Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037] 0.4224844313339796 0.0340657027700121 0.9728247578269504 1.0 1.0 2 Q10567 1 +BAG domain superfamily [IPR036533] 0.4009836065573725 0.0281034645787204 0.9775796308319802 1.0 1.0 3 O95429,Q9UL15 2 +Ribosomal protein L14 superfamily [IPR036853] 0.3985578498852735 0.026651524504545 0.9787376772237208 1.0 1.0 2 Q6P1L8 1 +Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155] 0.3700426089806563 0.0213753935787654 0.9829462021601892 1.0 1.0 2 Q96AX1 1 +R3H domain superfamily [IPR036867] 0.3675409836065514 0.0048304343970866 0.9961458859606684 1.0 1.0 3 Q9H6S0,O95453 2 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f34bdb182557e43aa49300bbd11658c9843e1204 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "APC, N-terminal coiled-coil domain superfamily [IPR036149]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Actin-related protein 2/3 complex subunit 5 superfamily [IPR036743]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenomatous polyposis coli protein [IPR026831]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "CalX-like domain superfamily [IPR038081]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Calycin [IPR012674]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Copper homeostasis (CutC) domain superfamily [IPR036822]", "Copper type II, ascorbate-dependent monooxygenase, N-terminal domain superfamily [IPR036939]", "Copper type II, ascorbate-dependent monooxygenase-like, C-terminal [IPR014784]", "Core-binding factor, beta subunit superfamily [IPR036552]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DUSP-like superfamily [IPR035927]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Focal adhesion kinase, targeting (FAT) domain superfamily [IPR036137]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "Green fluorescent protein [IPR009017]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "H/ACA ribonucleoprotein complex, subunit Nop10 superfamily [IPR036756]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone chaperone ASF1-like superfamily [IPR036747]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrase-like, N-terminal [IPR017856]", "Integrin alpha, N-terminal [IPR028994]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "Janus superfamily [IPR038596]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Lipid transport protein, beta-sheet shell [IPR015819]", "Lipovitellin-phosvitin complex, superhelical domain [IPR011030]", "Longin-like domain superfamily [IPR011012]", "LysM domain superfamily [IPR036779]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHM/PNGase F domain superfamily [IPR008977]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Rad4, beta-hairpin domain 3 superfamily [IPR042488]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Receptor L-domain superfamily [IPR036941]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rubisco LSMT, substrate-binding domain superfamily [IPR036464]", "Rudiment single hybrid motif [IPR011054]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAS-6, N-terminal domain superfamily [IPR038558]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Seven-hairpin glycosidases [IPR036026]", "Sialidase superfamily [IPR036278]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Snake toxin-like superfamily [IPR045860]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "Sushi/SCR/CCP superfamily [IPR035976]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thyroglobulin type-1 superfamily [IPR036857]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transcriptional regulator TACO1-like, domain 3 [IPR026564]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transglutaminase-like superfamily [IPR036985]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "Tubby-like, C-terminal [IPR025659]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vitellinogen, beta-sheet N-terminal [IPR015816]", "Vitellinogen, open beta-sheet, subdomain 1 [IPR015817]", "Vps53, C-terminal domain superfamily [IPR038260]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YebC-like [IPR029072]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "mRNA decapping protein 2, Box A domain superfamily [IPR036189]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOBEC3C", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASCC2", "ASCC3", "ASF1B", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATXN10", "AURKA", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT1", "BCAT2", "BCL10", "BCL2L12", "BCL2L13", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPHL", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRD8", "BRD9", "BROX", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BZW1", "BZW2", "C1QBP", "C2CD5", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASP2", "CASP3", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX4", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2AP", "CD2BP2", "CD302", "CD320", "CD46", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDYL", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPM", "CENPV", "CEP170", "CERK", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHRAC1", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLIP1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNOT1", "CNOT4", "CNOT9", "CNP", "COA7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPE", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT2", "CPVL", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CUTC", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAKD", "DCP2", "DCPS", "DCTN1", "DCUN1D4", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOHH", "DPF2", "DPH2", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERH", "ERLIN2", "ERO1A", "ERP29", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAM120B", "FAM234B", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FREM2", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLPH3L", "GOPC", "GORASP2", "GOT1", "GOT2", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C3", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IDE", "IDI1", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPDH1", "IMPDH2", "INF2", "INTS12", "INTS14", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRS4", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIRREL1", "KLC1", "KLHDC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8E", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSS", "LTA4H", "LTN1", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MAP2K1", "MAP2K4", "MAP4K5", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED16", "MEPCE", "METAP2", "METTL1", "METTL13", "METTL7A", "MFGE8", "MFN1", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPI", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL4", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS15", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NBR1", "NCAPD2", "NCAPG", "NCBP1", "NCDN", "NCK1", "NCL", "NCOA5", "NDRG3", "NDUFA10", "NDUFA9", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEK9", "NELFE", "NENF", "NEU1", "NF1", "NFATC2IP", "NFS1", "NHLRC2", "NHP2", "NID1", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PAM", "PANK4", "PAPSS1", "PARK7", "PARN", "PARP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHPT1", "PI4KB", "PICALM", "PIK3C2A", "PIN1", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNO1", "PNP", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB39A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABEPK", "RABGAP1", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL5", "REL", "REPS1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF219", "RNF220", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RRAGC", "RRAS2", "RREB1", "RRM1", "RRM2", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RTCB", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SCAF11", "SCAF4", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SET", "SETD1A", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMPDL3A", "SMS", "SMU1", "SMYD2", "SMYD3", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1", "SPECC1L", "SPEN", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX10", "STX12", "STX3", "STX5", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFCP2", "TFRC", "THADA", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM14C", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TROVE2", "TRRAP", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTI1", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TULP3", "TWF1", "TWISTNB", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UGCG", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VLDLR", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR73", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "XAB2", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZDHHC13", "ZFR", "ZFYVE16", "ZMYND8", "ZNF281", "ZNF346", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZRANB2"], "leading_proteins": ["ACP2", "ADGRE5", "AFG3L2", "AIFM1", "ANKLE2", "AP1B1", "AP2M1", "AP3S1", "APP", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP7A", "BAG4", "BAG5", "BCL2L13", "BSG", "BTN2A1", "CALM3", "CALU", "CAMK2G", "CANX", "CD276", "CD302", "CD47", "CERK", "CETN2", "CLCN3", "CPE", "CPVL", "CTDSPL2", "CTSA", "CTSB", "CYB5B", "DLD", "DNAJA2", "DNAJC1", "DNAJC11", "DNAJC16", "DNAJC2", "EEF1D", "EFCAB14", "EGFR", "EHD1", "EHD4", "EIF5", "EPHA7", "ERAP1", "ERCC4", "EWSR1", "F11R", "FKBP14", "FKBP7", "FKBP9", "FLOT1", "FNTB", "FOXRED1", "FTO", "FUCA1", "FUCA2", "FUS", "G3BP1", "GAA", "GALNT1", "GALNT2", "GALNT7", "GBA", "GGA2", "GLA", "GLB1", "GLT8D1", "GMPPB", "GNA13", "GNAI2", "GNAI3", "GUSB", "HDGFL2", "HEXA", "HEXB", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HPSE", "HSP90AB1", "HSP90B1", "IFNGR1", "IGF2R", "ITCH", "ITGAV", "KEAP1", "KIAA0319L", "KIF22", "KIRREL1", "LDLR", "LETM1", "LGALS3BP", "LMAN2", "LNPEP", "LRP1", "LRP2", "LTA4H", "MAN1A1", "MAN2B1", "MANBA", "MAPRE2", "MCAM", "MFGE8", "MFSD8", "MGAT1", "MGST2", "MICU1", "MICU2", "MIPEP", "MORF4L2", "MPP2", "MRC2", "MRPL14", "MRPL45", "MSTO1", "MTCH1", "MTOR", "NAGLU", "NAP1L1", "NAP1L4", "NBR1", "NID1", "NLN", "NNT", "NPC2", "NPEPPS", "NRP1", "NSF", "NT5C3B", "NUCB1", "NUCB2", "NUTF2", "NXF1", "OCLN", "OSBP", "OSBPL8", "OSBPL9", "OTUB1", "PAM", "PARN", "PCYOX1", "PDCD6IP", "PGRMC2", "PITPNA", "PLA2G15", "PLXNB2", "POR", "PPT1", "PPT2", "PRKAR1A", "PROCR", "PTPRF", "RABGAP1", "RCN2", "RETSAT", "RPL37", "RPS3", "SCPEP1", "SDF4", "SEC22B", "SEC63", "SEZ6L2", "SLC25A10", "SLC25A15", "SLC25A19", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC2A1", "SLC4A2", "SLIT2", "SMS", "SORL1", "SQLE", "SQSTM1", "STARD3", "STARD7", "STX10", "STX3", "STX5", "STX7", "SV2A", "TAF15", "TAP1", "TBC1D10B", "TBC1D15", "TBC1D9B", "TIMM44", "TMED7", "TMPO", "TRAP1", "TSN", "TSPAN3", "TSPAN6", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UGCG", "UNC119B", "VAMP7", "VCP", "VDAC1", "VDAC2", "VDAC3", "VLDLR", "VPS33A", "VPS37B", "YKT6", "YTHDC2"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..19d1a5fecec9e93403e4d52e64906ce288859b36 --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "EGF-type aspartate/asparagine hydroxylation site [IPR000152]"} \ No newline at end of file diff --git a/interpro_ptm/advanced/plot_0.png b/interpro_ptm/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2ef622f845fc478c56043b5a887028686d55a6b2 --- /dev/null +++ b/interpro_ptm/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9115362d540b5fc36cfc403d36ad489a111805a86fffdc3b90e026be7073212a +size 167629 diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..19d1a5fecec9e93403e4d52e64906ce288859b36 --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EGF-type aspartate/asparagine hydroxylation site [IPR000152]"} \ No newline at end of file diff --git a/interpro_ptm/basic/plot_0.png b/interpro_ptm/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..74318d31d521058030b6d1a3e09a8a47674abc23 --- /dev/null +++ b/interpro_ptm/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d3c9f1eeac6bda333963a076a5ae1cf449c5a77895f3b87d8f4afc1cb26a7190 +size 148818 diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c199daae9089432168f6c4876874e0f1d329897e --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a486bd64fffaf4eeddc58cb0b08a95db43a7bf03148338c40ce81dfd60906f93 +size 68431 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..249699d0f13de5f46465f4910a518dcc795fac55 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +EGF-type aspartate/asparagine hydroxylation site [IPR000152] 6 7 2.7801279151250786 0.0054337490064062 1.1703703703703705 2.466666666666667 -0.1373915694631231 0.3902853831950666 1.067180945982341 1.5160051467387146 1.437469353479462 0.3143260829565273 0.0006097953864012 0.1635258499471353 0.3009165941166509 2.4880325513906888e-05 0.0017617577033715 +P-type ATPase, phosphorylation site [IPR018303] 4 5 2.0721355443489498 0.0382528023490802 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0108675670250155 1.0 1.0 0.0153906222854723 0.0034992238505004 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..100322f76e0acc1131daa47073d8283868d238d5 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 3.5 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2aa9b5ced14ad143dfd898c2e0d15eb320c5a8ba --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..053d49f9cd1d03e0f9453a9463a6d8c125c11aa4 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EGF-type aspartate/asparagine hydroxylation site [IPR000152] 0.9326986211424796 2.7801279151250786 0.0054337490064062 0.0215584831236875 0.021734996025625 7 P98164,P48960,P98155,Q07954,P14543,P01130 6 +P-type ATPase, phosphorylation site [IPR018303] 0.8549868766404107 2.0721355443489498 0.0382528023490802 0.1444533046579714 0.0765056046981604 5 Q9HD20,P16615,Q04656,P05023 4 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..23379845637d269ca03bfcbcfba94a31f714aa50 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ADGRE5", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP7A", "EIF5A", "FASN", "LDLR", "LRP1", "LRP2", "NID1", "SLIT2", "VLDLR"], "leading_proteins": ["ADGRE5", "ATP13A1", "ATP1A1", "ATP2A2", "ATP7A", "LDLR", "LRP1", "LRP2", "NID1", "VLDLR"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..b29a5f7b5d047f9ef61055df504dc125377e92b5 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]", "1": "LDLR class B repeat [IPR000033]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..6c3dd51d5a4d031003c45fdc03dcbe6bd7788479 --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:89ffb2df541d32849c9cc43bc252ef7d4dcb8f6e33749b692d9cc02fa1d64abd +size 189971 diff --git a/interpro_repeat/advanced/plot_1.png b/interpro_repeat/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..a1c6276ac1d31d0274eba5ebb86c518adb76b13b --- /dev/null +++ b/interpro_repeat/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8daed37f9e94019d57e0387746431b058ce8a2cf854f8dd60c3cb3b7df92650f +size 173799 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..94f96b03a3b5e48168eea09f512fb4d0e2440bfe --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]", "1": "LDLR class B repeat [IPR000033]", "2": "Spectrin repeat [IPR002017]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..9670e880b97f9864388ca802b97acd14e627ef33 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version 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file mode 100644 index 0000000000000000000000000000000000000000..c601f48b6f8f3fd78f538a1d75476f0c464debf6 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:66f051427d4a934bc98487adc070196d9727195561dfc99d823ad369968e3d60 +size 72839 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9295150d4bd8107cc32556fabe14e7d806fb9b67 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 11 20 2.9277210348251104 0.0034145625858088 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 1.7308787445871593e-08 1.0 0.0513963234576887 0.000273959679835 1.279082532544537e-07 +LDLR class B repeat [IPR000033] 5 6 2.684894464232686 0.0072552711607678 0.9836734693877552 1.697959183673469 -0.549615492605431 0.2178830578377484 0.912352182889183 1.204835461019448 2.0954686485482377 0.2766983586353521 1.655833142626512e-06 0.0516364610584135 0.0047533286028597 7.940914593690878e-08 4.765057901286244e-06 +Low-density lipoprotein (LDL) receptor class A repeat [IPR002172] 4 7 2.328348255408172 0.0198936188923386 1.1577669902912622 2.2135922330097086 -0.4618571585064355 0.3784040995227052 0.963842866820141 1.321226889644718 1.4657719604998898 0.3224476960770873 0.0007725705229972 0.0875404472016038 0.014058804472369 7.054294597105141e-05 0.000200465132953 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c840281a07b346db753afce8bd97818813fe6b03 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 84, + "title": "Average number of proteins per term", + "value": 4.976190476190476 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e52fb6ad32ec9ec5078e70ded3ea0e05cca3e69e --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..00e60c364fffec2827d2c083e3c06feaa4086e59 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,11 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.7009736508517049 2.9277210348251104 0.0034145625858088 0.2497239419422849 0.286823257207944 20 P12235,P12236,Q70HW3,P05141,Q9HC21,Q6NUK1,Q9UBX3,Q9Y619,Q9H2D1,Q9BSK2,Q9NZJ7 11 +LDLR class B repeat [IPR000033] 0.9373153921890404 2.684894464232686 0.0072552711607678 0.4575527133826167 0.2954077403226316 6 P98155,Q07954,Q92673,P14543,P01130 5 +Low-density lipoprotein (LDL) receptor class A repeat [IPR002172] 0.8301197884689442 2.3283482554081716 0.0198936188923386 0.8150943398100348 0.2954077403226316 7 P98155,P01130,Q07954,Q92673 4 +PFTB repeat [IPR001330] 0.8433300557194494 1.1054393116803287 0.2689692775638839 0.9999999999962796 0.6846490701626136 2 P49356 1 +HEAT repeat [IPR000357] 0.6245518743959195 1.0516080726020145 0.2929794025488565 0.999999999999775 0.7212476747855598 5 Q8TEX9,Q6PJG6 2 +Furin-like repeat [IPR006212] 0.8167813831530686 0.9983501804339892 0.3181095825552704 0.9999999999999892 0.7217041183336832 2 P00533 1 +Sel1-like repeat [IPR006597] 0.7351687971156959 0.6837182033768354 0.4941531264754668 1.0 0.8055773937522069 2 Q9UBV2 1 +Hexapeptide repeat [IPR001451] 0.4905051855630949 0.1544337978990051 0.8772677064345509 1.0 0.9435599679879207 3 Q9Y5P6 1 +Spectrin repeat [IPR002017] 0.37130663164807 0.1452376563838073 0.8845232356293471 1.0 0.9435599679879207 7 Q01082,O43707,P12814,Q8WXH0,P46939,Q13813 6 +Kelch repeat type 1 [IPR006652] 0.3781450397157341 0.011052965579674 0.9911811889760798 1.0 1.0 3 Q7Z6M1 1 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3be8481d5dad2de489300a0ec53695f0b07a5786 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Adenomatous polyposis coli (APC) repeat [IPR041257]", "Adenomatous polyposis coli protein repeat [IPR009223]", "Adenomatous polyposis coli protein, 15 residue repeat [IPR009240]", "Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "CSPG repeat [IPR039005]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "FG-GAP repeat [IPR013517]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Furin-like repeat [IPR006212]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "Integrin alpha beta-propellor [IPR013519]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kelch repeat type 2 [IPR011498]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "MORN motif [IPR003409]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "Paired amphipathic helix [IPR003822]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "SAMP [IPR009224]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "YD repeat [IPR006530]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN4", "AGAP3", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKRD17", "ANKS1A", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "APC", "ARMC6", "ARMCX3", "ARPC1A", "ARPC1B", "ASPH", "BCOR", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CD320", "CDC20", "CDC23", "CDC27", "CDC40", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1B", "CORO1C", "CORO7", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF7", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DYNC1I2", "EDC4", "EED", "EGFR", "EHMT1", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTB", "FREM2", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GMPPB", "GRWD1", "GTF2I", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HIRA", "HTT", "HUWE1", "IGF1R", "IGF2R", "ILK", "IPO4", "IPO5", "ITGAV", "JUP", "KAT7", "KDELC2", "KDM2A", "KEAP1", "KLC1", "KLHDC4", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "LARP1", "LASP1", "LDLR", "LLGL1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8E", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MED16", "MKI67", "MRPS27", "MTCH1", "MTCH2", "NAA15", "NASP", "NEK9", "NHLRC2", "NID1", "NIPBL", "NISCH", "NLE1", "NOL10", "NOP2", "NOP9", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "P4HA2", "PAFAH1B1", "PAK1IP1", "PAM", "PDCD11", "PEX5", "PHIP", "PLAA", "PLEC", "PLRG1", "PLXNB2", "POLR2A", "PPID", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP5C", "PREB", "PRKCSH", "PRMT9", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABEPK", "RABGGTB", "RACK1", "RAE1", "RAI14", "RANBP2", "RANGAP1", "RAP1GDS1", "RBBP5", "RCC1", "RCC2", "RNH1", "RPAP3", "RRP9", "SART3", "SCML2", "SCRIB", "SEC31A", "SEH1L", "SEL1L", "SETD7", "SGTA", "SHOC2", "SIN3A", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SORL1", "SPTAN1", "SPTBN1", "SRP72", "STIP1", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL1XR1", "TBL2", "TBL3", "TENM3", "TEX10", "THOC3", "THOC6", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VLDLR", "VPS18", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR73", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "XAB2", "XPO1", "YTHDC2", "ZC3H7B", "ZDHHC13"], "leading_proteins": ["ACTN1", "ACTN4", 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0.0002471633761616 1.315197037857844e-07 +Ion transmembrane transport 59 151 3.001992923664626 0.0026821841051742 47.09466019417476 154.11893203883494 1.555073205784263 0.3634279635891347 19.61122797656 15.97124025754773 1.9676287128633565 0.411597796705808 2.834779013860847e-09 0.3775589691339882 0.2758742877890929 4.390557081423738e-05 2.297041502412207e-09 +Cellular homeostasis 49 135 2.9478611097999945 0.003199807916737 35.03155339805825 140.69660194174756 0.4666088113804902 0.5685618966047314 11.62423291193178 14.777892439656425 1.1736922314243927 0.3887657095146841 3.090054413549297e-06 0.3323602521916406 0.0504194425753612 0.0006017717127542 1.2621099436605317e-06 +Glycoprotein metabolic process 29 59 2.934877524433796 0.0033367936570827 18.59223300970874 59.577669902912625 0.8707431654759812 0.409720724299967 7.543964208858723 9.989377193127202 1.488085349392555 0.3835029669336279 4.345804227918e-05 0.0942961333107097 0.021569556805469 3.4198860580636795e-05 9.856653642370086e-05 +Lytic vacuole organization 18 27 2.914836260051152 0.0035587520179893 8.677184466019417 23.79368932038835 1.067589638534915 0.1668002350701783 2.8744208086829883 3.077266940940983 2.0111064761459874 0.2496786569477077 1.0064855938144913e-08 1.0 0.0025924072114898 1.508991918600535e-06 1.5433059254884104e-08 +Antigen processing and presentation of peptide antigen 7 13 2.9009969001158176 0.0037197755811793 4.050970873786408 11.99271844660194 0.9279525789651738 0.3302951212632576 1.9792182503824105 1.8740552023113428 1.0022067378347963 0.2823588878170496 4.859295195370152e-05 1.0 1.0 0.0012549484261259 0.0001729005795719 +Divalent inorganic cation homeostasis 20 50 2.8698674088725284 0.0041064395296095 15.361650485436892 54.019417475728154 0.5485088157809707 0.5170537035394376 6.04857242197355 6.215359275440269 1.1779017300469032 0.3778837346959196 0.0166479524608299 0.2194767361872623 0.2574752425413383 0.0339633893520725 0.0033985336295831 +Inorganic ion transmembrane transport 39 109 2.843196150325774 0.004466357356416 32.300970873786405 111.99514563106796 0.9881513097876132 0.4268253140664947 13.185263141323642 11.586314982845243 1.7161030277526947 0.4113555760685328 2.171991336726347e-05 1.0 1.0 0.0192862853602071 3.670720164642188e-06 +Entry into host 18 36 2.814817188556685 0.0048804988276642 7.968446601941747 31.24514563106796 0.6061616104105989 0.3954837799611526 3.566493820193545 3.4119437173329663 1.31706945612869 0.333413728218646 1.5547556254934481e-07 0.0734458650364987 0.0601458293215769 8.028477240317548e-05 4.053038280602076e-07 +Glucose import 6 13 2.799617592045597 0.005116317766225 3.4563106796116503 11.364077669902912 0.3176045676169922 0.5089134846135845 1.8514056534885703 2.196305563870774 0.9183417404528994 0.3012736273802708 0.0020343441612113 1.0 0.0693457394610891 0.0230341265569123 0.0055591316089767 +Amyloid precursor protein catabolic process 9 18 2.788925471477661 0.0052883233143712 4.62621359223301 16.47087378640777 1.203006467000838 0.2754962460876 2.1329801006381106 2.1803683249886516 0.947433834000198 0.2709877848980267 0.00815731977733 0.0188245552589776 0.000811364430178 0.0006205149914719 0.0048940429574069 +Protein targeting 27 102 2.785965180146889 0.0053368604099131 30.48543689320388 111.54126213592232 1.595466660966077 0.3336055854889273 10.683999539888966 11.70327920021055 1.673091584234216 0.3988264387816677 0.0013069922537738 0.0068519784881021 0.0104311471068346 0.0191473301817845 0.0025244162214331 +Lysosomal protein catabolic process 6 8 2.781307962512531 0.005414035129764 2.6941747572815533 6.587378640776699 0.838918419522322 0.2080383809566978 1.5899151374262637 1.8707342212441815 1.5239608036504366 0.2420459791980847 3.672695435763492e-06 1.0 1.0 0.0007869115437374 1.2147954097366526e-05 +Protein catabolic process in the vacuole 6 8 2.781307962512531 0.005414035129764 2.70873786407767 6.618932038834951 0.8383076008345888 0.2101105309103242 1.6017652153393662 1.88837291272598 1.5176899437744062 0.242508547144668 8.336851087471846e-06 1.0 1.0 0.0011993766429203 2.7180346417726147e-05 +Regulation of vesicle mediated transport 41 116 2.780089385935714 0.0054343937663012 24.555825242718445 117.33252427184466 0.2091879024365628 0.7679552913580993 8.949930305556254 13.223750714091672 0.6695514077553656 0.3058083256414907 3.316445941662687e-05 0.8042578165154122 0.3985398668948996 0.0319354726941985 0.0003707326958016 +Amyloid beta formation 4 12 2.778865974655551 0.0054549026746686 3.4466019417475726 11.150485436893204 0.7369482521385301 0.3719348072839057 1.602353580483856 1.6769930201386472 1.043709172018907 0.2948415726419107 0.0112320362960444 0.0115082778780227 0.0002983067426918 0.0012549484261259 0.0229507437408614 +Vacuole organization 26 51 2.774182276761573 0.0055340661398841 14.220873786407768 51.74514563106796 0.8524122478550634 0.3147425083910056 5.370022076358251 7.439112114793103 1.7567175511320523 0.3563110134355993 1.5463724823704608e-05 1.0 0.0620226994518361 0.0003790552488406 5.854600298420302e-05 +Golgi vesicle transport 44 118 2.772574518357451 0.0055614784364446 32.30825242718446 130.0995145631068 0.5186556770214802 0.6391424830765352 11.558195085956042 14.851278907933963 1.0581936514451007 0.3745819971007444 0.000421390669106 0.037035881913773 0.0408976472683376 0.0116878222785546 0.0001857717530512 +Cation transmembrane transport 42 118 2.7697778578616097 0.0056094535973398 33.43446601941748 118.4004854368932 1.1701058025505957 0.4085228823574113 14.425169362008605 12.553856783980793 1.6663185381795875 0.4066910074955585 8.088169950297345e-06 0.5413773680429788 0.7029584933927696 0.0094839223449001 1.957832760108608e-06 +Nucleotide transport 10 14 2.7662548188645 0.0056704206815525 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 4.55193856063163e-07 1.0 0.0019068669696529 2.914413274201657e-05 2.07553330550362e-06 +Membrane lipid biosynthetic process 14 25 2.762490520314496 0.0057362227488233 8.866504854368932 23.050970873786408 1.3229385051208649 0.2431293012321725 4.229937732502716 3.4850337476777224 1.635527795490498 0.2996124846932806 0.0004416286412927 0.3274019772455256 0.1862598674919939 0.1374400519295191 0.000146373457931 +Antigen processing and presentation of peptide antigen via mhc class i 6 11 2.743159092547587 0.006085119590083 3.5533980582524274 10.33980582524272 0.9522781165124746 0.321717188118692 1.7458864571217907 1.7766194475253527 0.972074824811495 0.2764762653101907 1.7092923511963007e-05 1.0 1.0 0.0017432511761074 5.493155547881244e-05 +Ph reduction 10 13 2.737010424077181 0.0062000328389817 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 1.030202474140748e-05 1.0 0.0293903981750984 0.0004989114687539 4.205073922679249e-06 +Import across plasma membrane 12 19 2.736518111572141 0.0062093176799957 6.601941747572815 18.643203883495147 0.5666543433877399 0.4743790616320767 3.944616106748078 3.664494750162088 1.0498181035479843 0.3397186310535848 0.0034615954670857 1.0 0.5213291194813008 0.1123101919918835 0.003548440361811 +Oligosaccharide metabolic process 5 7 2.712088360443364 0.0066860767391569 3.0606796116504853 6.179611650485437 -0.0148577354153068 0.2267163537664357 1.4017006052191363 1.1242135739548185 1.7186048285621385 0.2671195008920222 0.0019559053195249 0.1049896535105009 6.176416462866221e-05 1.3582842958771772e-05 0.0006318501388434 +Inner mitochondrial membrane organization 11 18 2.6918993000188296 0.0071046393533795 9.985436893203884 20.800970873786408 1.138268089020681 0.2873707765098114 4.6289277788641146 2.4012939531921327 1.609232985153232 0.3229583948801056 0.0006097953864012 0.1635258499471353 0.3009165941166509 0.2256009180273313 5.121649611699266e-05 +Glycolipid catabolic process 6 8 2.672762858996196 0.0075229410195389 3.6310679611650487 6.451456310679611 0.1059933679561382 0.1697430158083476 1.434595381284437 0.7664524352299261 1.9023109688101565 0.2365791262889882 3.198666701588262e-06 0.0014481500629001 3.74476751148508e-06 1.5560435214860637e-07 3.903860956515125e-07 +Sphingolipid biosynthetic process 10 17 2.6589362698237724 0.007838778920179 6.543689320388349 16.33252427184466 1.3108583596388097 0.2293036031089034 3.2058099533310203 2.4273143169149307 1.5209865792019848 0.2861850290041513 0.0024507962227594 0.2480154974279715 0.1100932826860655 0.1714591409165242 0.0004875982127202 +Organic anion transport 26 44 2.6548039523520583 0.0079354512507257 18.575242718446603 46.57281553398058 1.6158560948583975 0.2692356013040078 9.46386426798458 5.9518324529926545 1.7470285445738305 0.3371920110610632 6.939169737470186e-08 0.5027324490187645 0.0124644356717177 0.0001914371667194 1.5503702447762626e-06 +Vitamin transport 8 10 2.6535998452907 0.0079638205825396 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 3.23304802908002e-05 1.0 0.2070995190727305 0.0024379570615939 1.0761884384293304e-05 +Amyloid beta metabolic process 4 14 2.64889432598634 0.0080755578259359 3.6771844660194177 13.24514563106796 0.6724101183977472 0.416551332754989 1.8088680779022668 1.8049556184618043 1.0101286409291856 0.3102485572243311 0.0240434368582593 0.0164667175849867 0.0006187487433082 0.002945649466309 0.0469837238449897 +Membrane protein proteolysis 4 11 2.6405892463365603 0.0082761991647857 4.138349514563107 11.781553398058252 1.0093176076341577 0.3069750059979975 2.078037067185485 1.3902746514167437 1.0484204695389652 0.2877212872591311 0.0218127504116087 1.0 1.0 0.0720513532108381 0.0428945912137629 +Regulation of glycoprotein metabolic process 7 11 2.629325531107603 0.0085554419607489 3.592233009708738 10.70631067961165 0.6804974065630551 0.4353046559123504 2.03935499608955 1.985055569049905 0.9883671343018048 0.3255557758909779 0.0007508895708755 0.0078974776787256 0.0001376480525375 0.0004989114687539 0.001918269568256 +Ceramide catabolic process 6 8 2.61594387670795 0.0088981181968121 3.8592233009708736 6.531553398058253 0.1286784152295923 0.1423502941444668 1.429436503356119 0.7012295128365029 2.0219843992394857 0.2259194528389771 3.198666701588262e-06 0.0561990347849709 0.0001778916397324 5.522373670119844e-06 3.903860956515125e-07 +Mitochondrial membrane organization 20 43 2.604109288505991 0.0092113379123854 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 2.9509431352592596e-05 0.0108990791164893 0.0648989212296417 0.0288939483426972 6.646895390280867e-07 +Lipoprotein metabolic process 11 25 2.602843636887792 0.0092454109562387 5.504854368932039 19.114077669902912 1.0723975558987071 0.2794846862458811 2.648039342123219 3.7213756556771336 1.2556798055308762 0.2951644225033464 0.0001497642123657 1.0 0.5614825641059915 0.0010205325993841 0.0007767330813302 +Glycoprotein biosynthetic process 23 50 2.6025633560795907 0.0092529716874607 16.72087378640777 51.87378640776699 1.042113998842759 0.381483262234126 6.756316800759528 8.908847583990125 1.5232206853916193 0.3819786061588057 0.0006933243906781 0.0628703537261178 0.0360421294767493 0.0007156962418899 0.0009063024716897 +Cytochrome complex assembly 6 11 2.5783147104066875 0.0099283529711857 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 0.0003538454783329 0.151306852499084 0.0041517217414646 0.0088087297166582 0.0010440793255692 +Regulation of plasma lipoprotein particle levels 9 16 2.572159688935646 0.0101066262677873 3.0485436893203883 14.031553398058252 0.231208625789076 0.3303314046534408 1.822878555656895 1.834532430195746 1.3070593144112836 0.2560846117575656 0.0001921127754615 0.1389130578490434 0.2590666885683055 0.0063239101987386 0.0005790030159305 +Vitamin transmembrane transport 5 7 2.5610398838402526 0.0104359374816547 2.9344660194174756 6.094660194174757 1.6910321805591797 0.1136175735100163 1.344920850275403 0.8913122381585616 1.0580472895861666 0.1862049292817703 1.5614620157482445e-05 1.0 0.1349531130589082 0.0051503840765812 4.367834065541858e-05 +Chloride transport 7 13 2.561024257873577 0.0104364068816875 4.33252427184466 12.12621359223301 1.0302584084066435 0.2341882174183942 2.3624510960969567 2.26059366569241 1.2797232968088257 0.2563105728143979 3.850614189823082e-05 0.1471951297158956 0.0398064357050217 0.0010916803236277 0.0001380057592112 +Vacuolar acidification 6 9 2.556011112550999 0.0105879737478018 3.4757281553398056 8.922330097087379 1.27407749822917 0.1611429668415415 1.4148632661931722 1.303016071016461 1.4195929612668792 0.2212670077717619 3.672695435763492e-06 1.0 0.0126574737404708 0.0007869115437374 1.2147954097366526e-05 +Proteoglycan metabolic process 4 7 2.55504787068999 0.010617319502854 3.0558252427184467 7.347087378640777 0.90943742591388 0.2775323863615319 1.813993622553226 2.3052106999156825 1.19959130355936 0.2714444012698452 0.0289328707312566 0.0180235679120217 0.0640285846884502 0.0198035379531722 0.0558327828623465 +Regulation of amyloid precursor protein catabolic process 4 16 2.5505790096844625 0.0107544144669562 3.8859223300970873 14.189320388349516 0.723751929535891 0.4024575578925681 1.8731873759514015 2.0164571748807374 0.9921534445034136 0.3036488689822377 0.0086829766575463 0.0102371045657047 0.0002347353167816 0.0009447024772989 0.003914644875648 +Receptor mediated endocytosis 17 59 2.540132297862848 0.0110810543889603 10.939320388349516 54.74514563106796 0.2974076350556154 0.559708876603857 5.491273529430237 7.364675641797722 1.1085365989015756 0.3550743208777513 0.0034315763502317 0.0363369268895495 0.0154457523693027 0.000316786843242 0.0028634592081741 +Carbohydrate transmembrane transport 6 16 2.534731126632505 0.0112533663419811 4.012135922330097 14.080097087378642 0.1345934828511105 0.552100805518534 2.094224211847023 2.682357315361447 0.8764783529730497 0.2919122713750917 0.0112551624208181 1.0 0.1163398228410075 0.0600215848699845 0.0275888658736797 +Mucopolysaccharide metabolic process 4 8 2.5329236956097945 0.0113115573302535 3.400485436893204 8.912621359223301 0.5894446998893683 0.2689339883290864 1.6227448151896249 1.7256308603927724 1.433353391777711 0.275728271795533 0.0344085387640767 1.0 0.3530974878629287 0.0044406378118471 0.0655768501043339 +Protein localization to vacuole 6 17 2.5292629535065387 0.0114302355890214 5.20873786407767 20.24757281553398 0.5437651170857908 0.3970016112497027 2.9079938968471533 3.678442701839641 1.178287503307516 0.309681546976434 0.0800865993790726 1.0 0.0173242512102645 0.048897845662748 0.0570529296125973 +Antigen processing and presentation of exogenous peptide antigen 3 6 2.527728150640985 0.0114803205871003 1.6067961165048543 4.686893203883495 0.987028524507588 0.2895214995402835 1.1019631322504793 1.05964046762731 1.0509935492639806 0.2645206747413269 0.0076717987785406 1.0 1.0 0.0011993766429203 0.0143001062154138 +Metal ion export 6 8 2.51936442824849 0.0117566904981309 3.779126213592233 8.553398058252426 0.5059205316086877 0.4155863674545267 2.112664358767855 1.499049247815051 1.150738830143596 0.3315496346975708 0.0012644948297495 1.0 1.0 0.090818300458346 3.907616018373289e-05 +Regulation of t cell proliferation 6 18 2.5183901287994632 0.011789265858495 4.548543689320389 17.20873786407767 0.3678090213411445 0.5562508690900512 2.4712075613347495 2.4125725220194325 0.8250230708720367 0.3041137280888924 0.0227305005949391 0.2870659866655126 0.1454623761357323 0.0068401475593005 0.052504971472103 +Regulation of lysosomal protein catabolic process 4 6 2.515929136604918 0.0118719050105797 1.1820388349514563 3.344660194174758 0.359320837781623 0.3612070071329659 1.1335003430162958 1.3137235419699895 1.333216779855555 0.3035682445298419 1.1721396217376793e-05 1.0 1.0 0.0010588751859522 2.8311070051942505e-05 +Regulation of protein catabolic process in the vacuole 4 6 2.515929136604918 0.0118719050105797 1.2014563106796117 3.3762135922330097 0.3553822840909967 0.3561494889357127 1.140898051797836 1.3189129213804007 1.3434272672921512 0.3030873575434169 4.016995029489519e-05 1.0 1.0 0.0020064706347618 9.569573614901708e-05 +Lipoprotein biosynthetic process 9 17 2.503905649471477 0.012283078477719 3.837378640776699 12.817961165048544 0.5159177916871569 0.4870101230655305 2.4216380804227313 3.0215034704254133 0.9442820469649724 0.3192432047465013 0.0049659548920841 1.0 1.0 0.0756483536674149 0.0140935967091553 +Locomotory behavior 8 29 2.498747513092223 0.0124633073882587 7.186893203883495 29.01456310679612 0.367578136549174 0.4129867938447028 2.855164467106169 2.964970497634466 1.254834886476281 0.3178953925587394 0.0146082621127237 0.3685774959165274 0.0632956597671369 0.0004757717240761 0.0407161489813638 +Cristae formation 6 9 2.4964666512517137 0.0125437462862509 4.740291262135922 8.861650485436893 0.8982766043222677 0.3392698633906088 2.216011442046921 0.6593503673812457 1.2485531022675598 0.3418736408093433 0.0172110563640188 1.0 1.0 1.0 0.0003671727016274 +Regulation of lysosomal lumen ph 5 7 2.4946396938818616 0.0126085085949687 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 1.5614620157482445e-05 1.0 0.0088504827764808 0.000371706641515 4.367834065541858e-05 +Circulatory system process 32 69 2.4807380852878524 0.0131110671997285 17.152912621359224 72.00970873786407 0.7968086684699157 0.4206667688960129 5.8797345113877215 8.195718922280731 1.282615010632819 0.3676426088525382 0.0001246657094127 0.6926728433724869 0.4122661284261001 0.0022745586199253 0.0006901481908917 +Antigen processing and presentation of exogenous antigen 3 9 2.476522546349079 0.0132669245330852 2.0800970873786406 7.682038834951456 0.7846141280949802 0.3912377722563422 1.42818099743969 1.069601013737802 0.957994485343778 0.3040877622263243 0.0170860114395222 1.0 1.0 0.0028478177309091 0.0308662830144804 +Nucleotide transmembrane transport 4 9 2.461103057156382 0.0138510573109766 4.029126213592233 9.24271844660194 1.3657020532080593 0.1972377481261837 2.230443861436908 1.484326001257553 1.1744026177454787 0.2553979780962895 2.4133268249961338e-05 1.0 0.000440337804097 2.812625820330817e-05 6.703246650942136e-05 +Metal ion transport 31 97 2.460058785619926 0.0138914260003382 24.868932038834952 99.21116504854368 0.6600358663497399 0.5322554902435589 9.162889792248723 11.473971032908404 1.1670714049066973 0.3920241658733104 0.0039031874134866 0.5023005139274972 0.8528521180554104 0.080590415234033 0.003122413379997 +Vascular transport 7 15 2.454949080490537 0.0140904545571383 4.774271844660194 13.094660194174756 0.7274519419599351 0.3186647470404632 2.3913310677559982 2.1617303908189505 1.2183781465172474 0.2807075669512824 0.0008147663499995 0.2145132052152406 0.0832345551471358 0.006984722202598 0.0025854516113679 +Glycoside catabolic process 4 6 2.4339906699967218 0.0149333800073419 2.995145631067961 5.604368932038835 0.914408298188202 0.1915126053981477 1.4021397407455505 0.554137429771367 1.5051386650706404 0.245673751384095 5.388804179699288e-06 0.0006219606051344 4.656667989155393e-05 2.1797401302891516e-05 1.3106068439724131e-05 +Macroautophagy 36 102 2.4308492331158207 0.0150634812371548 25.570388349514563 102.68203883495146 0.4734815024857951 0.6429834425349866 8.949285204664525 14.162660044372751 0.8554944786686205 0.3590213706304501 0.0011187363688315 0.725682415483212 0.7277592499916454 0.1103501291422771 0.0023987970858388 +Positive regulation of locomotion 23 96 2.430704124621347 0.0150695148906927 17.813106796116504 82.76941747572816 -0.0202856110636012 0.6872652647880098 6.785301293884359 10.926397031402892 0.7474886342310336 0.3042029503813403 0.0025877489703567 0.4267494331732555 0.5565250106410763 0.0026813416216771 0.0115193235093361 +Vascular process in circulatory system 12 32 2.422191026610528 0.0154272385141644 8.218446601941748 31.361650485436893 0.5302527350177477 0.4259259059419516 3.6564678051714665 4.365329555745678 1.181021277396986 0.3310828049268227 0.0017420947071234 0.4158765777114258 0.2890592178487741 0.0014642245811675 0.0027401058887407 +Antigen processing and presentation 9 22 2.4177863331966343 0.0156152430151788 6.201456310679611 22.17718446601942 0.8231471183465873 0.4220086818460768 2.970845032857872 3.056135613532617 0.9682333159777928 0.3245513416930483 8.344950437358128e-05 1.0 1.0 0.0024554723849656 0.0003655904724143 +Mitochondrial respiratory chain complex assembly 17 36 2.4175331001899982 0.0156261127189323 14.427184466019416 38.300970873786405 1.6683402305651691 0.229838901803248 5.648441561419256 5.588363345618 1.6629328950455762 0.3088219725228932 7.056517382694692e-05 0.3561784256622231 0.0017929291584427 0.0064725887331866 6.651802149315022e-06 +Inorganic anion transmembrane transport 5 9 2.416297712275968 0.0156792356783188 3.4101941747572817 8.983009708737864 1.1245392058053427 0.2357455210082705 2.3748669786284156 1.7214248641786654 1.1968417731555627 0.2697184972505711 0.0009148667339154 1.0 1.0 0.0049571663496986 0.0023211498250519 +Cerebellar cortex development 4 11 2.411459295888326 0.0158888252908848 3.2014563106796117 12.951456310679612 0.4913835354280507 0.4216383686135529 1.7737836843231067 1.855867843348426 1.0191189701346923 0.2901119129344551 0.0126796388195528 1.0 0.2872333566147377 0.0097601039903573 0.0257423149537502 +Purine nucleotide transport 7 11 2.411059058206574 0.0159062725374294 4.970873786407767 10.817961165048544 0.961055494000064 0.2880106547862709 2.8308505383502496 1.988649275322177 1.3314072021441097 0.3042395363852717 0.0001017286916656 1.0 0.1758008751515455 0.0011993766429203 0.0002747300414667 +Carbohydrate transport 6 18 2.4094955886055884 0.0159745891852982 4.725728155339806 17.317961165048544 0.1347863377600586 0.585526017516962 2.279077100704329 2.835860465716908 0.8210424195743269 0.2894489471893008 0.0297797332779157 1.0 0.1588529428511447 0.1044322137967542 0.0670258998725707 +Endoplasmic reticulum to golgi vesicle mediated transport 27 65 2.40697471429744 0.0160852835258127 17.32766990291262 65.39077669902913 0.808881464821498 0.4942452999677598 7.539018980743236 6.620812461410292 1.284359804176963 0.3933269611423161 1.4797893388722666e-05 0.0176779282664691 0.0246695053344801 0.0215851652574667 9.788867531437944e-06 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 12 23 2.405019222470882 0.0161716151278228 7.771844660194175 26.825242718446603 1.1714448828781496 0.3436005361805324 3.811248488859092 3.450558374586287 1.1733172803389544 0.345676809182098 0.0112121181580077 0.0014578554854327 0.0102837000876808 0.0053616069246772 0.0070893533545687 +Protein localization to plasma membrane 24 70 2.399824842117676 0.0164029186553567 17.50485436893204 74.02427184466019 0.04078352472809 0.7298603923114082 6.16421521774153 8.588736878541509 0.688616631852129 0.3019343547464078 0.0028099636759585 0.6489372683198866 0.6160018336713062 0.0778611934121107 0.000751364561901 +Mitochondrial transport 17 75 2.394532872807408 0.0166415516237588 26.76456310679612 83.42233009708738 1.9353944346565397 0.260698067067068 11.29934298946582 6.8259418360610375 1.9296757414965091 0.3685496297416806 0.0001649265386701 0.0012471197288945 0.0056874611143685 0.0026907227290202 0.0005402851353645 +Protein localization to cell periphery 24 81 2.39398555341176 0.0166664052247949 19.616504854368937 83.97087378640776 -0.0728406604687701 0.738131331337791 6.830366194214173 9.82413939083103 0.6457113535761634 0.292469237941277 0.0180468242694395 0.717422297152983 0.7159444952216597 0.1773996040600024 0.0075839987543255 +Hormone metabolic process 15 30 2.382540682638284 0.0171936320687142 8.95631067961165 28.65776699029126 1.130508313948193 0.2963365150575847 3.9674689274001818 2.5345884681715156 1.346801337886388 0.3240077568826507 0.0057786209503224 0.3746890061856052 0.0665208936004256 0.0090970875375293 0.002487044867352 +Plasma lipoprotein particle clearance 8 14 2.3802464256316087 0.017301063883758 2.8033980582524274 11.597087378640778 0.2841472336869506 0.2922439265613805 1.7215617505529983 1.5431625772865891 1.3638326625090953 0.2354738993646769 8.336851087471846e-06 0.0919337377678228 0.1758008751515455 0.0011993766429203 2.7180346417726147e-05 +Negative regulation of developmental growth 3 11 2.3734309351319283 0.0176236886407274 2.6067961165048543 10.118932038834952 0.4177621670448362 0.5151603515616955 2.0822300468824904 1.7258544598953018 0.8590834947670382 0.302034516552393 0.1743595432330578 0.2295798469686227 0.0949012099695084 0.1423397245441582 0.2663234719844228 +Protein transmembrane transport 13 25 2.3657296264355043 0.0179945803949181 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 0.0012099624570291 0.0020640692536444 0.0142561824639166 0.0016834035897202 0.0009139057009217 +Adult behavior 5 20 2.364849629301791 0.0180373928871286 4.924757281553398 19.364077669902912 0.6031935344655648 0.4116465050786389 2.137657889318908 2.190772988063693 1.071812274679601 0.3090358289458393 0.047239863313943 0.2695684389372801 0.1290920553826253 0.0047615333276254 0.0946135485635064 +Regulation of glucose import 3 9 2.360732025802938 0.0182389047465845 2.7427184466019416 9.031553398058252 0.4006150731161149 0.4855839033057929 1.6030372835271705 2.017273588927774 0.9030919727667402 0.2937882051217688 0.0516532455250465 1.0 0.2872333566147377 0.2076979954646016 0.087821349317486 +Regulation of cell killing 5 8 2.357791685378397 0.0183840061286684 2.844660194174758 8.366504854368932 0.4041102541319114 0.4507662844932221 1.5842506516490529 1.3031494402288128 1.0522249449787806 0.3118972087461248 0.0065645821697015 1.0 1.0 0.0056128198685199 0.0027845492980534 +Localization within membrane 55 167 2.357413604710937 0.0184027369644368 43.83252427184466 179.48543689320388 0.7329824809593914 0.5973922945503244 12.803162929787796 21.32668417309247 1.133148805830878 0.4087008058998355 1.16222104837779e-05 0.0270276045374723 0.0418069049940507 0.0031816116135815 7.570634641565942e-06 +Neuron projection guidance 7 23 2.354670661054292 0.0185391285096179 5.662621359223301 23.189320388349515 0.4437647002001748 0.5678522712486597 2.931294310088859 4.519975354803488 0.8912373776728286 0.311775964869191 0.1764109533982916 0.1354750356227081 0.3700525131557232 0.1068426745449518 0.3256495415439318 +Aminoglycan catabolic process 4 5 2.3536849767788026 0.018588356793088 2.6893203883495147 4.728155339805825 0.5164809724591738 0.1764823388548578 1.1619294817897845 0.7656988020633148 1.69808407883546 0.2279588459746903 6.657801000522381e-05 0.0561990347849709 0.0056684159955205 5.522373670119844e-06 0.0001575214550341 +Glycosaminoglycan catabolic process 4 5 2.3536849767788026 0.018588356793088 2.6432038834951457 4.665048543689321 0.5167433573606753 0.1777854895826483 1.1305026922003756 0.6751064263980151 1.6910244329591049 0.2288538535307848 4.016995029489519e-05 0.0516364610584135 0.0047533286028597 3.2862197875785204e-06 9.569573614901708e-05 +Membrane invagination 4 12 2.3521901074380445 0.0186632337068637 3.6941747572815538 12.16019417475728 0.0473496567323534 0.6174394728479946 2.548303271138053 2.060626721793156 0.8509677037136445 0.3077347987860288 0.0197211042902028 1.0 0.3143397790261298 0.0678108138951911 0.0390278099301106 +Neuropeptide signaling pathway 2 5 2.346623244304828 0.0189443998135265 1.0849514563106797 3.1189320388349513 -0.0985724577330871 0.419688363037091 0.853358156505566 0.8690642357540188 1.297775726458379 0.3194504309420363 0.0951107385425164 1.0 0.0002296483500821 0.003355333516566 0.0225979674873623 +Regulation of oxidoreductase activity 10 18 2.344083153779997 0.0190739183542167 4.745145631067961 16.524271844660195 0.8435277245089666 0.3527293456818395 2.542951562396442 1.641953963820047 1.0033906386071183 0.2899852749738094 0.0013711927142081 0.0276250495673642 0.0949012099695084 0.1423397245441582 0.001050513287845 +Membrane protein ectodomain proteolysis 3 9 2.332962078867193 0.0196501356791916 3.2815533980582523 9.42233009708738 0.914660566901433 0.3175120830558543 1.6482852268027584 1.2623319489295757 0.9882621955102872 0.2679281534911034 0.035175066535485 1.0 1.0 0.1724444479617574 0.0612536211646263 +Regulation of er to golgi vesicle mediated transport 5 7 2.329408399738315 0.0198374405081158 2.1966019417475726 5.915048543689321 0.8267152021532312 0.3699978591289015 1.4151359695885812 0.8244249231762646 0.9890575089615372 0.3183740962504898 0.0001046031266164 1.0 0.1180585699575878 0.0382400085743442 1.6279070379868977e-05 +Regulation of autophagy 33 92 2.3261075003090927 0.0200128165327608 20.118932038834952 94.3495145631068 0.711099590941891 0.531831837860264 6.9602150135047 11.998348379757145 0.9791686068293384 0.3767967479294735 0.0006752922569496 0.3774217541644473 0.2655243330236689 0.0151173218989615 0.0067670833059855 +Glycoside metabolic process 4 9 2.321445252049409 0.0202628256482151 3.283980582524272 8.611650485436893 0.5062828222010527 0.3204164092287125 1.4990079825210394 0.6824144700308834 1.298018080705215 0.2868097664691992 0.0002281841207161 0.0022827689145391 0.0003602808960722 0.000371706641515 0.0005289198821125 +Regulation of leukocyte mediated cytotoxicity 5 7 2.3200635117269925 0.0203374418475246 2.5825242718446604 7.334951456310679 0.4511695306521209 0.4227043221453989 1.4499700153890709 1.2995300672557608 1.082342679990832 0.3098039206468536 0.0023896230640102 1.0 1.0 0.0024379570615939 0.0008083265510004 +Positive regulation of cell killing 5 7 2.3200635117269925 0.0203374418475246 2.344660194174758 6.594660194174757 0.4156629456801037 0.4127481983530973 1.3626949423444794 0.9467730739010484 1.1172564974004802 0.3098028662961327 0.0012644948297495 1.0 1.0 0.001453665706999 0.0003689915939861 +Protein localization to lysosome 4 14 2.319557059430542 0.0203648510537386 3.5364077669902914 14.37621359223301 0.6191344010889903 0.3619681772746835 2.0811532251007954 2.18038858944462 1.1869570048706093 0.3022181269423334 0.0159423888090386 1.0 0.0052800410185589 0.0118572988629309 0.0319540971359957 +Chemical homeostasis 69 174 2.3173804587927376 0.0204830158721198 43.762135922330096 177.7597087378641 0.7082111793088889 0.511106347874914 13.668464281922288 17.87763227716401 1.3204137511810292 0.4179418895476048 8.163045471327824e-08 0.5069729194216077 0.1674308857789419 0.0004539886166923 5.6752333911283475e-08 +Organic acid transmembrane transport 15 30 2.314841555173666 0.0206216048199394 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 0.0013893027790946 1.0 0.1793408912067547 0.0128484864032106 0.0051522052257082 +Membrane organization 73 214 2.307358081907596 0.0210348660433035 62.02427184466019 223.60922330097088 0.9560408776070136 0.5603311757674675 21.467957454898308 21.375973545731355 1.611091026762519 0.4273954777865132 7.140259296112088e-11 0.2485042018361758 0.0674887916082271 3.087711330165882e-05 2.188907445917229e-13 +Regulation of regulated secretory pathway 9 16 2.300478416969514 0.021421130680028 5.135922330097087 19.024271844660195 0.5532028818011353 0.482650154445206 2.517120190261048 2.8085156919839167 0.8466655843360735 0.3050640843792452 0.0635667630477185 1.0 1.0 0.2403501019229617 0.1234458219460415 +Negative regulation of neuron projection development 3 18 2.3001751554115675 0.0214382987740568 4.944174757281553 19.932038834951456 0.8070712719008988 0.4165241941447024 2.3357271686464363 2.7475042016888107 0.8484003015222881 0.3001902418041021 0.2306382996383075 0.3241278561278478 0.0075904072731156 0.1331029981740636 0.3574963066401728 +Export across plasma membrane 4 7 2.299105515248343 0.0214989484074472 3.342233009708738 8.672330097087379 0.659462409318522 0.3364871063656119 2.046038764373277 1.5847916183398325 1.1961171404298503 0.3001696886640556 0.1199247419429496 1.0 1.0 0.5213399099817488 0.0137665493817408 +Cartilage development 6 13 2.298708537988288 0.0215214953825815 3.932038834951456 14.283980582524272 0.7074320636322524 0.4287139668901396 2.125947582774665 2.5119975572795252 0.8798730191625526 0.3016172221818579 0.0754987998918754 1.0 1.0 0.1788573615140471 0.152693888684589 +Mannosylation 4 9 2.298621098809277 0.0215264644000579 2.6262135922330097 6.966019417475728 0.6104715271961744 0.3620085753936749 1.5520397580890246 1.435949900284761 1.1183031747274563 0.2897179829421447 0.0041077133853001 1.0 1.0 0.0267619345648551 0.008785557350241 +Phospholipid transport 5 14 2.296814174185373 0.021629372631821 4.038834951456311 13.844660194174756 0.8595089147672731 0.22382450694892 1.931709490395295 2.5542930986961077 1.4491821424024287 0.2459407475876757 0.0164354132133173 1.0 1.0 0.0345596402774107 0.0359869143678365 +Vesicle docking 6 15 2.296138761536197 0.0216679486379789 5.046116504854369 16.300970873786408 0.2955335573812314 0.5566344803804099 2.726231700974349 2.3037957343391864 0.8857805503827542 0.3078464388536641 0.0090993160258402 0.1952735388158895 0.3530974878629287 0.0044406378118471 0.0055591316089767 +Ion transport 76 201 2.29362101916802 0.0218122769735182 59.95631067961165 203.33495145631068 1.28794420214731 0.4483240343684334 22.7179419701651 20.293344878478432 1.852388371824549 0.4292871393353351 1.6332446381921344e-11 0.186058060279213 0.0821292627403398 9.293058378368536e-06 1.1033946530441084e-10 +Regulation of blood pressure 9 16 2.292754961133128 0.021862116337967 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.0085995143684978 1.0 1.0 0.0515621560092188 0.0065824357934952 +Regulation of organic acid transport 5 10 2.2863608668639044 0.022233155726641 3.0266990291262137 9.95873786407767 0.5438090247089712 0.4615742763522461 1.7589620109651245 1.3814816722984091 0.8909245759390145 0.2944812864916606 0.0170860114395222 1.0 0.2147385524083838 0.4587195489148998 0.0308662830144804 +Response to ph 3 5 2.284208713474046 0.0223592677230741 1.7621359223300972 5.140776699029126 0.3480088533355521 0.3739523760080299 1.2528504590681426 1.153124661134805 1.2011912824917792 0.2945428652003891 0.0076717987785406 1.0 0.1758008751515455 0.0834574734746242 0.0143001062154138 +L amino acid transport 8 12 2.2763586487051257 0.0228245525081114 5.114077669902913 11.91504854368932 0.7755289387861473 0.3283794523692901 2.998235059113201 1.3256494094845783 1.3058948249973923 0.3189923022900864 0.0471991190444314 1.0 0.2802926639431586 0.1988041978590851 0.0807266025333323 +Behavior 19 76 2.2752933968814464 0.0228883352918325 16.990291262135923 75.04126213592232 0.2909440827671418 0.5405324846032677 5.526186812971979 8.403983472903677 1.109438409605415 0.3578193814797769 0.0067492873012469 0.3739570139316887 0.1182369000459649 0.0023758507524062 0.0394358105348858 +Lipoprotein localization 4 6 2.269591362675395 0.0232323881737541 1.7451456310679612 4.762135922330097 1.33870340128666 0.2150435313503844 1.1193794779630346 1.3835803073772095 0.999398972942542 0.2555578059866495 0.0010133941165421 1.0 1.0 0.00262770885776 0.0001575214550341 +Selective autophagy 13 31 2.26813912667215 0.0233207282599097 7.861650485436893 28.031553398058257 0.6116968756419903 0.5194450063363468 3.450451665126401 4.3159755745103565 0.9002253779314615 0.3454803983634653 0.0014301696482668 0.2766173679843171 0.4775398588675821 0.0789974698724344 0.0048394274978242 +Cerebral cortex cell migration 5 12 2.267186641498347 0.0233788265287571 2.6674757281553396 9.648058252427184 0.4999506202354539 0.4636840357787796 1.6746570252811468 1.507238559179189 0.9155030768279568 0.2982482407508992 0.0075723509134359 1.0 0.2590666885683055 0.1724444479617574 0.0157766780310383 +Positive regulation of protein exit from endoplasmic reticulum 4 6 2.2668516086918187 0.0233992922073256 1.7014563106796117 3.842233009708738 0.6319527754438191 0.4528969328253339 1.0729226103046268 0.876811779781035 1.0096007730201175 0.3294914749708005 5.388804179699288e-06 1.0 0.0743799864466655 0.0148625463558957 1.3106068439724131e-05 +Early endosome to golgi transport 2 7 2.265838376991299 0.0234612807279179 2.320388349514563 6.650485436893204 1.001706299736163 0.3202433583076141 1.526233973035193 1.1381191933763375 0.8656979853859356 0.2689019049302471 0.0110460525898298 0.0561990347849709 0.1094892401774078 0.00262770885776 0.018020673376298 +Axon development 19 73 2.262953722150693 0.0236385421982856 15.014563106796116 75.88349514563107 0.4221802741874887 0.6742105443551618 6.65661081388802 8.797672872875632 0.8036898770047755 0.340363217999487 0.3003254665738569 0.4133246230882367 0.151199283707238 0.099850420720062 0.349803580625232 +Steroid metabolic process 30 65 2.2568777852489417 0.0240157125086288 17.82766990291262 66.9247572815534 0.9974586731388552 0.3270410156332073 6.090491666967852 5.93996409793671 1.7133199907504504 0.3720334828404655 2.952147117522002e-07 0.1723298875515411 0.0632048376565007 0.0014269891364106 4.553905254955686e-07 +Antigen processing and presentation of endogenous antigen 4 6 2.2548451455256338 0.0241430504437996 2.6529126213592233 6.463592233009709 1.0779744166035472 0.2832041157954688 1.4492771087670022 1.3990755299770097 1.00991421519493 0.2818848392729987 0.0002281841207161 1.0 1.0 0.0051503840765812 0.0005289198821125 +Antigen processing and presentation of endogenous peptide antigen 4 6 2.2548451455256338 0.0241430504437996 2.638349514563106 6.390776699029126 1.097011591019633 0.2766562869747734 1.460743657586565 1.3760123823390067 1.0015631459591094 0.2785574288267012 0.0001573276205306 1.0 1.0 0.0041946485896371 0.0003671727016274 +Cytosolic calcium ion transport 8 21 2.242017126906884 0.0249602654114156 6.567961165048544 23.944174757281555 0.4634706877593821 0.4616211122842976 3.323605294530572 2.8902732844456565 1.0331628024603872 0.3216839736311487 0.4533804183649856 1.0 1.0 0.6143274539738884 0.1181853417157704 +Lysosomal lumen acidification 4 5 2.240743133955207 0.025042718357374 1.9077669902912624 4.094660194174757 1.0430284513288333 0.1731957374320673 1.0102570393282595 1.1504623937719378 1.495459416196642 0.2154807950267566 4.016995029489519e-05 1.0 0.0047533286028597 0.0020064706347618 9.569573614901708e-05 +Synapse assembly 4 17 2.234730374345176 0.0254350552479958 5.468446601941747 17.45873786407767 -0.3282763699124831 0.545572046602979 2.899861817023056 3.166227481604147 0.8429479411025542 0.2967774114004993 0.2084810837773378 0.0539251864958397 0.1724639155075248 0.0405286386671015 0.1772555379782259 +Cellular transition metal ion homeostasis 8 22 2.230068079883354 0.0257429235437847 5.893203883495145 20.42233009708738 0.9608801516152976 0.3243056832171095 2.800529150274697 2.6932649561537056 1.130076157725316 0.3011842711337114 0.0011481456390341 0.003696507335194 0.0244837275894334 0.0047615333276254 0.003940654279348 +Amyloid beta clearance 6 12 2.226556269152971 0.0259769443840884 2.0509708737864076 9.781553398058252 0.4002973882884584 0.4992490702724125 1.5887419548660706 1.7210432359369072 0.9239665506826532 0.3028953012168623 0.0127437063312673 0.1049896535105009 0.1993869387044997 0.0020705519968491 0.0042957165481444 +Receptor metabolic process 11 34 2.2252236941249235 0.0260662249909109 8.254854368932039 34.48300970873787 0.1190654259323194 0.6256821363336791 3.854212262351103 4.138641335837385 0.844404065510763 0.3109475309665375 0.0087560439668309 0.3926779415133941 0.2605001929873321 0.0124287342519901 0.0276253268562706 +Proton transporting two sector atpase complex assembly 3 5 2.222894870464264 0.0262228897525131 1.7432098765432098 4.6839506172839505 1.079697689782964 0.2705190312822739 1.1688274457451555 1.1775111637565157 1.0292886485906785 0.2668917829180481 0.0019212906643037 0.0652597674910206 0.0077184558590264 0.0439142352380576 0.003721367796782 +Odontogenesis 3 12 2.2226000895507947 0.0262427781773479 3.0436893203883497 10.150485436893204 0.0188457924623822 0.6134096503134358 2.086255059987354 2.106779338665241 0.8165250819809797 0.2933225498978621 0.1990528229728135 1.0 0.4242240140575919 0.4035011436345253 0.2992569105103682 +Intermembrane lipid transfer 2 7 2.21778476840654 0.0265695111537351 1.966019417475728 6.618932038834951 0.4006158968389467 0.3501200832710581 1.370213887212628 1.5743486325272755 1.2182069511780798 0.2776659407244052 0.1290050643080269 1.0 0.2590666885683055 0.1724444479617574 0.1889957663081205 +Response to iron ion 2 6 2.215766390869397 0.0267075053453786 1.4150485436893203 6.157766990291262 0.5979544282259851 0.368314840518974 1.2978947657210995 1.0201193838747311 1.001337934980002 0.250562551485827 0.0450897184240335 0.0919337377678228 0.1758008751515455 0.01180448121602 0.0701952648708137 +Multi multicellular organism process 11 31 2.2131448124316195 0.0268876634513632 5.817961165048544 26.4004854368932 0.4199141861061661 0.4886319217993659 2.805744405393114 2.878999920293513 0.979235550100524 0.3132681877599969 0.0006035907965583 0.0627750690965546 0.0483217377147592 0.0002056124603596 0.0007767330813302 +Chloride transmembrane transport 4 6 2.2127549122452685 0.0269145473057936 1.9271844660194175 5.497572815533981 1.0121969151812915 0.2503571453769561 1.6864793094247907 1.5080669592016671 1.1003731395705292 0.2453144412674818 0.0004396452857286 1.0 1.0 0.0074273483269255 0.0010053263520343 +Sulfur compound transport 5 7 2.2088451366446846 0.0271854143285845 3.504854368932039 9.429611650485436 1.339223354728307 0.2167503093092372 2.046184165461596 2.1092484385198076 1.0728301411615704 0.2604171804663498 0.0099013119315747 1.0 0.2732850813359189 0.1899587232036964 0.0203628052401783 +Regulation of pattern recognition receptor signaling pathway 6 18 2.205830405146579 0.0273958765457702 4.691747572815534 19.70873786407767 0.80673262224624 0.4173389113947272 2.517825740704142 3.173406084005513 0.919675411949683 0.3119180769844089 0.1055425936028938 1.0 0.0216384292134882 0.0629955787418294 0.0298513421744587 +Negative regulation of leukocyte mediated immunity 3 5 2.204475834453564 0.0274908976154559 1.4684466019417477 5.152912621359223 1.0166590601943912 0.2872549002772236 1.1850502896064032 1.2860024091145663 0.9722873313503664 0.2687277537722931 0.00917939970768 1.0 1.0 0.0135296171343662 0.017002584405276 +Endoplasmic reticulum membrane organization 3 7 2.1984301019495893 0.0279184705369843 3.5679611650485437 8.12621359223301 0.656874598832497 0.271683145803182 1.813579499342004 1.2879547393790816 1.532817064292788 0.2945772195616556 0.0014173012232216 1.0 0.1180585699575878 0.0382400085743442 0.0027630263410089 +Glycolipid biosynthetic process 5 10 2.193422091693872 0.0282769820918808 3.3009708737864076 8.701456310679612 0.8778541677747596 0.2891249509557468 2.0940737065519093 2.1465026455410077 1.206628042966233 0.2848826766737565 0.0142484022426952 0.1594721229818057 0.2941077913158182 0.0558093330619567 0.0287420990175065 +Atp transport 5 6 2.186162423938941 0.0288037242989187 3.4805825242718447 6.233009708737864 0.5838786306840471 0.3211615036091749 1.83337760624298 0.8807971179633459 1.3636108978108328 0.3170401972517012 1.1721396217376793e-05 1.0 1.0 0.0010588751859522 2.8311070051942505e-05 +T cell proliferation 7 25 2.1816909049865942 0.0291323526203781 6.194174757281553 24.145631067961165 0.2896787294882859 0.6336134652888596 2.9709213778788497 2.668251916718813 0.7427908859202356 0.3020071268550194 0.0326350405088471 0.3593003709489177 0.2213471409258044 0.0068649912287255 0.0778250722651817 +Peptide catabolic process 4 10 2.179028738633946 0.0293295333600149 3.871359223300971 10.351941747572816 1.5413280472635258 0.1625248535751528 1.454973091229298 0.9501768442987896 1.1353491763523988 0.2229381591694359 0.0007725705229972 1.0 1.0 0.0009779431698101 0.0017429018144962 +Forebrain cell migration 5 13 2.178420071275437 0.0293747769317052 2.754854368932039 10.643203883495143 0.3716752606613158 0.5143956606967683 1.6795748214156283 1.5221272248168376 0.8705261141382955 0.2951589837207004 0.0159423888090386 1.0 0.3009165941166509 0.2256009180273313 0.0319540971359957 +Cation transport 56 152 2.171921021959673 0.0298616205439745 40.9247572815534 152.4733009708738 1.0106305648473772 0.4693050539746304 15.98502541638414 15.374508146736815 1.5607432077940149 0.4143686874753333 1.0372340478437944e-05 0.4300237614022896 0.710352350224794 0.0092721899351048 7.663280315615315e-06 +Regulation of lipid transport 7 19 2.170782398239632 0.0299476251000512 4.084951456310679 16.67718446601942 0.3665821344953645 0.5500608719110902 2.096012568417446 3.1783802180721676 0.8243482455883206 0.2999534514421824 0.0033632287867975 1.0 0.4515227909961177 0.0168986737095617 0.0098122663634215 +Positive regulation of t cell proliferation 4 11 2.168037764101319 0.0301558133717418 2.7475728155339807 9.599514563106796 0.5532192709084727 0.4333591055805664 1.6218678348817797 1.3191273068698348 0.9842106594117432 0.3010582825504118 0.0142484022426952 0.1594721229818057 0.0466281418945222 0.0016346598494465 0.0287420990175065 +Regulation of lymphocyte mediated immunity 6 21 2.1673252149940785 0.0302100651644807 6.019417475728155 20.953883495145632 -0.0931725806349676 0.5651789140416597 2.561782535218954 2.2350494588518615 0.911938960284987 0.3109357112566066 0.0211671511471286 0.2835996474450377 0.4876012483283494 0.0063798653120075 0.0180976191812076 +Cell morphogenesis involved in neuron differentiation 15 87 2.162931303631101 0.0305464636764698 19.59223300970874 91.78155339805824 0.0633940435481119 0.7404601122693133 9.411763856852913 11.295279945325175 0.755341800166473 0.30636858572397 0.4933254332748676 0.249209743437674 0.2646670816945575 0.2569501649552117 0.6796189628567469 +Calcium mediated signaling 6 14 2.160306678971337 0.0307489362722197 4.538834951456311 18.50242718446602 0.6092287356409146 0.5038251477928647 2.523856388514679 2.605538151751357 0.8029171469877773 0.3120022623859673 0.4352440854002199 1.0 1.0 0.6013150674679382 0.5780515197764531 +Regulation of phagocytosis 5 16 2.159145010176021 0.0308389186508779 3.3179611650485437 14.968446601941748 0.3209190136413688 0.5915166201342027 2.2957046675959747 2.326811751466005 0.7840787087563237 0.2941325518261171 0.0072874968128423 1.0 0.3404254693467198 0.0198035379531722 0.0168189007239576 +Mitochondrion organization 59 176 2.157523705758798 0.0309648820961161 56.45873786407767 188.26941747572815 1.5905300936136977 0.4100157441778524 20.15716756472138 18.40319032732565 2.034523716094369 0.4327537677377048 1.56970339494956e-08 0.0001934883081307 0.0002548288391393 0.0001404250109299 3.836199370137538e-10 +Protein exit from endoplasmic reticulum 11 22 2.1562881121178843 0.0310611749533618 7.002427184466019 21.233009708737864 0.6943602976218084 0.4745028866201709 3.210645812910548 2.182026685495945 1.0430444956616387 0.3507892727806736 0.0002819083381744 1.0 0.3404254693467198 0.0854582473740603 0.0001790277584403 +Aminoglycan biosynthetic process 2 6 2.155743269564004 0.0311037174596413 3.0800970873786406 8.300970873786408 0.6387272076133388 0.2830924102482349 1.486473637192798 1.7113836533227735 1.3163721030030058 0.2655273000426038 0.2412275844301856 0.1835089509173778 0.0614247268920475 0.0808776862517318 0.3340933889960909 +Regulation of cholesterol metabolic process 3 7 2.154401286112179 0.0312087158107117 2.2936893203883497 7.036407766990291 0.4249970400619817 0.3648416816190511 1.505220359503101 1.431658251221006 1.1754439785533268 0.2764552996129673 0.0148145229851571 1.0 0.2070995190727305 0.0195244436529747 0.0269295467729808 +Ceramide biosynthetic process 5 11 2.1525556944366397 0.0313536137396206 4.033980582524272 10.24757281553398 1.048715387316577 0.2344614502118888 2.237979905601341 2.0281678881596505 1.4071730245015133 0.2685344998940062 0.0025464211549204 1.0 0.2872333566147377 0.2076979954646016 0.0062013164624522 +Response to manganese ion 2 5 2.1524078464764087 0.0313652462548574 1.6237864077669903 4.803398058252427 0.1657661936697436 0.3714959689201358 1.1370705133968653 0.8633239594876049 1.253188844081787 0.2928478007224994 0.013934678000077 0.0017062060788896 0.0066572828402184 0.003355333516566 0.0225979674873623 +Regulation of steroid metabolic process 6 15 2.152279916648593 0.0313753146210746 4.334951456310679 14.769417475728156 0.4748357054552781 0.3599056508632772 2.2294240946396933 1.955260926764874 1.2378399088740557 0.2930403635554361 0.0047059421450486 1.0 0.3955810682553247 0.1312000588255236 0.012256850099211 +Protein targeting to vacuole 5 13 2.151323750769091 0.0314506548794708 3.9441747572815538 15.055825242718448 0.398430957984614 0.4200771820268876 2.3315668402653484 2.59373592845287 1.1496285974512008 0.311969859629291 0.0471991190444314 1.0 0.0420348553288257 0.0484311287755044 0.0229507437408614 +Membrane docking 8 26 2.149523308384667 0.0315929404561496 7.973300970873787 28.83252427184466 0.3013065671948621 0.638505559524285 3.967313754164099 3.197937811998676 0.8147042438070861 0.3288047187933706 0.0196801291595247 0.2801168002074996 0.4825947600252522 0.0059425292278447 0.0166822263622692 +Low density lipoprotein particle clearance 7 12 2.1472240280778383 0.0317754506772487 2.628640776699029 10.633495145631068 0.2652848599989675 0.2775304047094778 1.52978680445189 1.394909057645927 1.3932465899654711 0.2286950604253255 2.4133268249961338e-05 1.0 1.0 0.0062267265321947 6.703246650942136e-05 +Inflammatory response 22 67 2.145607090224663 0.0319043392932392 13.228155339805824 68.3883495145631 0.4116983048649594 0.5194837377797665 5.6022172704029956 8.769134982645609 1.0984550499812151 0.3566163019943059 0.0610507453757796 0.1498123589191256 0.2804956905008622 0.0769206991719218 0.0855014239852513 +Connective tissue development 9 26 2.145056098712471 0.0319483619431635 6.759708737864078 24.91747572815534 0.897701915164713 0.400129048313066 2.7453452066208146 3.8608044632925673 0.8993390896039578 0.3237981500894625 0.0348238950149407 1.0 0.7117822455627678 0.0906136462679527 0.0928229237074456 +Regulation of protein exit from endoplasmic reticulum 4 7 2.1352720644985586 0.0327387934076561 2.487864077669903 6.131067961165049 0.614536574202818 0.458469843561175 1.597129798474628 1.7824129563144424 0.9381550143256092 0.3206976005104832 0.0009961844667822 1.0 0.1758008751515455 0.0834574734746242 0.00223229240551 +Heparan sulfate proteoglycan metabolic process 2 5 2.1322406701180108 0.032987066637877 1.766990291262136 5.121359223300971 0.5642898647972117 0.4173053251695717 1.1613006057834978 1.389918659730618 1.0230121456430192 0.3027926697750463 0.0641252131986868 0.0053672672920639 0.0202898922491691 0.0173886328284286 0.0981468657129251 +Cerebellar purkinje cell layer development 3 6 2.1311772695622806 0.033074540879797 2.191747572815534 6.961165048543689 0.8392766864609098 0.2843914142715297 1.2383946131318218 1.2878998490964535 1.1730456034866912 0.2696789702944095 0.0051652853071714 1.0 0.1596960736798767 0.0087554356838108 0.0097510399506001 +Protein maturation 19 68 2.1276469258822264 0.0333663684301424 16.635922330097088 69.29611650485437 0.7279397561088901 0.5092233260742579 5.6828366082703345 6.923625268615643 1.0037762420957868 0.3621314209884535 0.0005104159495366 1.0 0.128026117966102 0.0035721060761345 0.0018072660234054 +Sterol metabolic process 22 38 2.124106024070927 0.033661278899074 11.932038834951456 38.44660194174757 1.1656335789111734 0.2523239777622673 4.346099994655023 4.0619669904912925 1.6676089351046874 0.3062687621764124 1.3436358209486774e-06 0.0627750690965546 0.0089732445190698 0.0010205325993841 5.221498834984664e-07 +Establishment of protein localization to vacuole 5 14 2.12238786218841 0.0338051806258323 4.521844660194175 17.024271844660195 0.4258363140243343 0.4350316278309467 2.7059819557420526 3.223757863278806 1.1181009658786627 0.3126979331758455 0.0829506285973236 1.0 0.0588586045542952 0.0764078368784309 0.0469837238449897 +Regulation of lipoprotein metabolic process 3 5 2.117830699185349 0.0341894084047322 1.046116504854369 3.701456310679612 0.6091978775814731 0.4218860430434006 1.0049921344518642 1.1556941408177035 1.0188720733671397 0.3030177134713819 0.0010133941165421 1.0 1.0 0.0328731354880699 0.0019884945269669 +Regulation of defense response 20 81 2.113931444751056 0.0345211230634985 20.351941747572816 89.95145631067962 0.3090454403231809 0.6824878992411626 7.399483130499616 11.222488380567595 0.777906173710776 0.3278161680699026 0.1470708234838399 0.7647332751306481 0.5450847809673047 0.1818940324846059 0.0521024449766734 +Positive regulation of leukocyte proliferation 4 18 2.113766709891207 0.034535197596045 3.861650485436894 14.71359223300971 0.6007881424807215 0.4761380762722816 1.9750347653754128 2.1890082226375087 0.9342511129724644 0.3127219346815347 0.084885611651825 0.2443632781182481 0.107004894081217 0.0129296559640097 0.0611543838186325 +L alpha amino acid transmembrane transport 6 10 2.1125087032874483 0.0346428402605079 4.480582524271845 10.533980582524272 0.7590361902351016 0.3223730555033793 2.606398335255894 1.1951807271273862 1.273814103695318 0.3116596719827348 0.1478553480374041 1.0 0.2732850813359189 0.1899587232036964 0.2143350029099695 +Vesicle mediated transport in synapse 13 31 2.112427844096898 0.0346497688537572 8.410194174757281 34.65291262135922 0.012845110062081 0.7427654138729786 3.843313821085224 3.3440885768532955 0.5914392726913961 0.26968284576971 0.2744756502618401 1.0 0.7173661275208494 0.3867509927062335 0.1804057816925162 +Neuromuscular process controlling balance 4 12 2.11232551633418 0.0346585387243514 3.8810679611650487 11.723300970873789 0.1269749302219408 0.3318237886495486 1.6788029789058698 1.2889149409291965 1.4027465363164735 0.2954189115293261 0.0028892085995524 0.1135912525516411 0.0016986126979642 0.0002861885476851 0.0062616815035888 +Animal organ morphogenesis 32 97 2.10765971863363 0.0350604339617874 19.361650485436893 96.08252427184466 -0.07235094891032 0.7437722143004032 7.630278544978294 13.241336623234048 0.6349578991360847 0.292190269554689 0.4883388658687846 1.0 0.7581421783717961 0.4112602412005111 0.511903485351408 +Positive regulation of endocytosis 5 21 2.1051685014041626 0.035276643074088 4.560679611650485 19.640776699029125 0.3893750024867851 0.549188937881148 2.507020729109805 3.151065065533248 0.827344309517849 0.2971633472740571 0.0388393830788485 1.0 0.1194965359594502 0.0629955787418294 0.0792626216408109 +Negative regulation of amyloid precursor protein catabolic process 2 8 2.104703211708397 0.0353171507470266 2.645631067961165 8.78883495145631 0.7296788020743029 0.3749260712143212 1.4314957008524525 1.1001198531094605 1.057374600950545 0.3066940057573566 0.0293978333139378 0.0786913117950012 0.0005309775927247 0.0074273483269255 0.0078812527225172 +Appendage development 3 14 2.1040599886072595 0.0353732144938854 3.283980582524272 15.37621359223301 0.1480909574057644 0.5969421392568955 2.39526954512383 3.7053775187314058 0.7995041457403814 0.2918586249779653 0.7456680688391016 1.0 0.335158199257754 0.3536157347104673 0.7259244158443671 +T cell mediated cytotoxicity 5 7 2.1039195096082683 0.0353854688346484 2.3155339805825244 6.371359223300971 0.523676216262352 0.4362981633701682 1.467264629016786 1.0863026706760155 1.002848585470677 0.3105377797682886 0.0012644948297495 1.0 1.0 0.001453665706999 0.0003689915939861 +Neuromuscular process 6 24 2.1029602349911825 0.0354692456683765 6.682038834951456 25.487864077669904 0.5107907507501308 0.3958015985368521 2.5973040014911133 3.0533044809467955 1.2106508695866462 0.3144907539964949 0.016928050415156 0.2731012734555347 0.0254749821013702 0.0051340314390508 0.0401410360295106 +Mitophagy 4 14 2.1015903830661244 0.0355891730140052 4.174757281553398 14.737864077669904 0.7026339988268726 0.4220360300693995 2.5842209186951752 2.0501535109396865 0.9566781806577936 0.318538155650451 0.0075723509134359 0.1389130578490434 0.2590666885683055 0.0383377547470353 0.0157766780310383 +Mitochondrial transmembrane transport 18 47 2.1003529709079625 0.0356978027714993 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 1.3436358209486774e-06 0.0627750690965546 0.0089732445190698 0.0002056124603596 9.640650611383104e-08 +Regulation of neuron projection development 21 69 2.0980123380549096 0.0359040554761023 13.592233009708735 69.32038834951456 0.4627708713262993 0.6269884749906404 5.824182751460114 9.346058399998094 0.798447623110489 0.3496779713708587 0.3094139081538408 0.3774217541644473 0.1209534874863454 0.1248505787071662 0.4502795957596366 +Proteoglycan biosynthetic process 2 5 2.0966103046405227 0.0360280863400055 2.6432038834951457 6.677184466019417 0.8965384350791714 0.2873226841395866 1.6239641738792057 1.992745053805788 1.1569297556833695 0.2755887487741971 0.1675284322915351 0.0121686135974036 0.0443091130960601 0.2076979954646016 0.2403376761227438 +Regulation of synapse assembly 2 8 2.095085359001202 0.0361634052042896 2.5606796116504853 7.859223300970874 -0.0792788242373662 0.5395185567400329 1.7274785273339432 1.5932464806786577 0.9385185942947613 0.3087264731082229 0.2412275844301856 0.0172375696548913 0.0614247268920475 0.0808776862517318 0.3340933889960909 +Calcium ion import 4 10 2.094597958579957 0.036206746847017 4.516990291262136 12.686893203883496 1.0417029373125424 0.2391249176108038 2.3196506830054986 1.9148178088324157 1.3383409214307818 0.27915846054651 0.1879092473827993 1.0 1.0 0.0596874537258691 0.0319540971359957 +Glomerulus development 2 7 2.090148118525241 0.0366044963429399 1.8567961165048543 4.453883495145631 -0.1573189447373245 0.5230844038756486 1.3151017632684965 1.4279829844582697 0.981592431903197 0.3154240515239371 0.1383201070829027 1.0 1.0 0.181169408752189 0.2015708610705285 +Embryonic digit morphogenesis 2 8 2.0849679988272 0.0370722054423748 1.4684466019417477 6.54126213592233 0.5989020645284063 0.4429704011231127 1.569266266788618 1.559731853735315 0.934963282113679 0.3039103680308826 0.2521907315700498 1.0 0.3404254693467198 0.0854582473740603 0.1542690309953486 +Negative regulation of wnt signaling pathway 6 18 2.084789550185852 0.0370884076861273 5.060679611650485 20.194174757281555 0.0087918318852476 0.6803556762671831 2.8316360368034803 3.814403597472526 0.6483950531086285 0.2757461382520667 0.9370436675638036 1.0 1.0 0.7411626683120798 0.7760314635926249 +T cell mediated immunity 6 11 2.081410727625988 0.0373963275953521 3.0145631067961167 10.46116504854369 0.1197287002677679 0.5708409161470714 1.5856705277946497 1.582963486610934 0.8689627261999604 0.297636200564505 0.00815731977733 1.0 1.0 0.0040251974639471 0.0048940429574069 +Positive regulation of mononuclear cell migration 4 9 2.0807661991087314 0.0374553114158431 2.8762135922330097 9.45873786407767 0.0886382248774921 0.5417098390792167 1.6300328286079158 1.7054300369397768 0.9929662660604948 0.3187573347288022 0.0195634506709255 0.1178616319260966 0.2223047329091382 0.0033024410276518 0.0074494564855197 +Neuron recognition 3 7 2.080285337863128 0.0374993688322049 1.9368932038834952 6.189320388349515 0.7447638338644241 0.3705616592284931 1.1064234596616862 1.175429078554095 1.011644937344681 0.2892876339238009 0.0251537295289499 0.1263420182810564 0.0293903981750984 0.0294507732567689 0.0446088038944012 +Regulation of membrane lipid distribution 2 6 2.076955819123634 0.0378056371203197 2.2475728155339807 5.5 0.9490281853542848 0.2470521989607894 1.5110816970578842 2.070950253254846 1.235309366119274 0.2447223644308076 0.094236132613279 1.0 0.2297987482657219 0.0267619345648551 0.1410707299584872 +Regulation of endocytosis 14 49 2.069608201454926 0.0384890494171243 10.009708737864075 47.5 0.2037917795721605 0.7044250618242573 4.669140886094089 7.163655572753937 0.7141975042751962 0.2991283724992093 0.005592018816943 0.5027324490187645 0.1608702453512187 0.0237635173186347 0.0227314668466147 +Memory 4 10 2.064150522751704 0.0390034469577498 2.405339805825242 8.388349514563107 -0.0748247495242427 0.5692325656366838 1.5821426515864156 1.7093859097696993 0.8297311978516596 0.280650564703965 0.0898326656168626 0.2480154974279715 0.4353012614103685 0.1714591409165242 0.1573271124776855 +Regulation of amyloid fibril formation 1 5 2.0631151985474268 0.0391016844953178 2.2888349514563107 5.662621359223301 0.5261836595996398 0.3490055624244857 1.4817896559260575 1.2503440001723864 1.197683561482515 0.297347360341851 0.0706927703013995 0.0516364610584135 0.1008375048293403 0.027832231049335 0.0968157430558884 +Maintenance of location 21 69 2.059858866129044 0.0394120350583093 14.529126213592232 67.10194174757281 0.2761251361558006 0.5437230382448518 5.781761264023897 6.826866977938762 1.0069098531292424 0.349986956897805 0.0069286096690486 0.070184605369373 0.012227438591947 0.0529618301439016 0.0167527929122959 +Amino acid transmembrane transport 8 14 2.058932688265819 0.039500687145175 6.213592233009709 14.228155339805824 0.7890307267204019 0.3318923540291705 3.493823914060917 1.9561661273054285 1.3497309258640615 0.3227865040448734 0.1215530548172949 1.0 0.3655284832956332 0.3157753203157507 0.1928878867570688 +Regulation of nitric oxide metabolic process 1 10 2.0588533004460885 0.0395082938754636 2.783980582524272 10.701456310679612 0.1430441353915724 0.5171013303945987 1.722054451404933 1.369110623206423 0.8984736114957514 0.280454644640389 0.3593880565727997 0.1389130578490434 0.2590666885683055 0.1724444479617574 0.4482773855235765 +Positive regulation of leukocyte migration 4 16 2.058180762449037 0.0395727845824094 4.097087378640777 15.49757281553398 0.0425334182634543 0.6319024426123137 2.2673904555241178 2.3008006061290747 0.8386767808878971 0.3052449059936994 0.1079334231167578 0.1952735388158895 0.3530974878629287 0.0230341265569123 0.0655768501043339 +Nadh dehydrogenase complex assembly 11 26 2.055351195985858 0.0398450957372304 9.266990291262136 26.96359223300971 1.1245271541492263 0.3013677937017552 4.122702675359976 4.029157649894909 1.4460543016521823 0.3224564676521605 0.0019593441096619 0.2406936845278361 0.0173242512102645 0.0120464435451714 7.642967523267423e-05 +T cell activation 14 58 2.0532325169957404 0.0400500321581913 11.87135922330097 56.20145631067961 0.3819132128629459 0.6116920144187052 4.9576316669096165 6.2667792486255545 0.7788461990309965 0.3330306669624288 0.0441207075835804 0.2998540533025085 0.375786201091113 0.0036591641650796 0.0518775451848926 +Adult locomotory behavior 4 16 2.05245462246182 0.0401255007314962 3.95873786407767 14.822815533980584 0.7389907423501648 0.3383620981823156 1.833016072372531 1.4878680371825237 1.1254592435779416 0.2897204029443448 0.0218127504116087 0.1755724648168266 0.0563311776114605 0.0026376358858749 0.0428945912137629 +Mammary gland development 7 22 2.052287803365141 0.0401417006275395 5.216019417475728 20.41747572815534 0.5512318000747981 0.5167791069166561 2.3942560065426757 2.728043047822029 0.8380822573448591 0.3178008321809467 0.0563083499416904 0.3371313972628795 0.0483217377147592 0.150785190751036 0.0536301543799238 +Regulation of monocyte chemotaxis 2 5 2.0505311521720446 0.0403126270492428 1.7985436893203883 4.563106796116505 0.2419118279045856 0.5315408384178865 1.2640272423687977 0.9943520397152368 0.9572879176135618 0.3175690600743351 0.0020442993800592 1.0 1.0 0.0004573905935078 0.0034377129995212 +Import into cell 12 26 2.0502089196463085 0.040344047954179 8.441747572815533 26.468446601941743 0.278986899549401 0.5712036628248293 4.717145431684204 4.63434566286081 0.9247855241772484 0.3264760057770247 0.0071479999807433 1.0 0.6211264656767345 0.2238556506104743 0.0090031046006091 +Sodium ion homeostasis 4 6 2.049228797466652 0.0404397473813671 2.466019417475728 6.349514563106796 0.2516746506702666 0.4899255287612532 1.608928570587902 0.9026254893696282 0.9888627771743224 0.3151555036236248 0.0394770304777161 1.0 1.0 1.0 0.0118865434534573 +Protein localization to endoplasmic reticulum 11 36 2.046904453001936 0.0406674667982456 9.50242718446602 34.50485436893204 0.9935384348474128 0.428255638055916 4.399083524593319 2.6617527855555916 1.1934894982037212 0.3717243536861919 0.0004298772769539 0.0305319028295214 0.0173242512102645 0.048897845662748 0.0003655904724143 +Cellular hormone metabolic process 7 16 2.0441766230868006 0.0409361017113489 5.441747572815534 17.32766990291262 0.9908884218524354 0.2940959275691314 2.8170777488519256 1.7185203072340225 1.2515909253444888 0.3031653223897966 0.054477447735962 1.0 0.3896854720293997 0.0345596402774107 0.0359869143678365 +Eye photoreceptor cell differentiation 2 5 2.043993805095785 0.0409541591469362 1.395631067961165 4.368932038834951 0.5347069230760966 0.4323383110298385 0.9834950258292608 0.788143834664171 0.9864809518799904 0.2899129502628464 0.0293978333139378 1.0 1.0 0.0074273483269255 0.0465653262864464 +Protein import into mitochondrial matrix 4 9 2.0382000528052795 0.0415299302340739 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0208795790121007 0.0022827689145391 0.0088504827764808 0.0051503840765812 0.0048822579474643 +Regulation of t cell mediated cytotoxicity 4 5 2.034406946250422 0.0419105820911185 1.674757281553398 4.135922330097087 0.7411503285093088 0.380666699308082 1.1042915794952284 0.779575982450709 0.9911557427348976 0.2979075232652237 0.0025369657709893 1.0 1.0 0.0051503840765812 0.0005289198821125 +Positive regulation of t cell mediated cytotoxicity 4 5 2.034406946250422 0.0419105820911185 1.674757281553398 4.135922330097087 0.7411503285093088 0.380666699308082 1.1042915794952284 0.779575982450709 0.9911557427348976 0.2979075232652237 0.0019212906643037 1.0 1.0 0.0041946485896371 0.0003671727016274 +Regulation of mononuclear cell migration 5 18 2.033910616523847 0.0419606083568835 4.548543689320389 16.800970873786408 -0.0451470857329185 0.6235913245378032 2.5976226650972936 2.65933034660148 0.8401157368959713 0.2924888202464074 0.0315964029051278 0.1913705796369965 0.3467918934582977 0.0040251974639471 0.0187017730028202 +Smooth muscle cell migration 7 13 2.026768376577392 0.0426861059626293 3.7305825242718447 10.385922330097088 -0.3189264558769314 0.4706229844860156 2.237746927414025 1.9306158466576009 1.0411294498318489 0.3050809049980993 0.0050795814366564 1.0 0.3209553841799009 0.0155108289838298 0.0119603409362114 +Autophagosome organization 12 23 2.025241311940404 0.0428425915274655 7.182038834951456 26.570388349514563 0.1959965762708488 0.6424664291527115 3.9411160656788633 4.6942845691516135 0.7864117658771023 0.3125757506363847 0.3245381461500034 1.0 1.0 0.6631309934563295 0.4735789670016921 +Glial cell migration 5 12 2.0231530965833286 0.0430573657037574 3.1480582524271843 11.75485436893204 0.4903114278901663 0.4024923853285767 1.6265160564973062 1.1535511772771148 1.0147729417330946 0.2731057446682498 0.0041077133853001 1.0 0.0274603336438859 0.0267619345648551 0.008785557350241 +Protein insertion into membrane 8 26 2.023144862442797 0.043058214387847 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 0.0042157085524802 0.0248381956323572 0.08610744549237 0.1257511849434855 0.0110551101007063 +Regulation of axonogenesis 6 23 2.020299438298124 0.0433523370451143 6.298543689320389 24.33009708737864 -0.0369493998932667 0.7042332477256763 3.680926674103965 3.330903692400873 0.6576030741176464 0.2748175369765668 0.332601816286336 0.3654998372428625 0.228437391614845 0.1935096580394825 0.3056367408200992 +Synaptic vesicle exocytosis 8 16 2.0184932053329225 0.0435399210993596 4.618932038834951 16.711165048543688 0.2860328341556032 0.6404005401290624 2.47961217317585 2.1079073508917427 0.6807802949393439 0.2890621858043471 0.116717007312396 1.0 0.4620800234731917 0.2020945775525867 0.1985748090604032 +Protein targeting to lysosome 4 11 2.014319990453593 0.0439759484883481 2.861650485436894 11.133495145631068 0.4665494631806399 0.3733123029661771 1.8767316131355816 1.7651272451933906 1.2080503341010538 0.3026029882111192 0.00917939970768 1.0 0.0170518298819148 0.0135296171343662 0.017002584405276 +Respiratory chain complex iv assembly 3 8 2.0117908199540144 0.0442419920579539 2.7475728155339807 6.451456310679611 1.036831430168084 0.2562354664331627 1.605321530277248 1.669274831081891 1.262804896468415 0.2848709091577191 0.0170860114395222 0.1135912525516411 0.0237627189197599 0.0217985290060267 0.0308662830144804 +Negative regulation of receptor mediated endocytosis 2 10 2.0108189840533885 0.0443445801666608 2.4514563106796117 9.135922330097088 0.0418365941063717 0.5479583438408402 1.7736126303830697 1.981950317724577 0.882698777390703 0.2936432911803512 0.0862378295439867 0.1178616319260966 0.2223047329091382 0.0242110622206542 0.1298078118605267 +Endosome organization 10 28 1.9980058453174545 0.0457160264086939 7.677184466019417 28.553398058252423 0.1938836583639464 0.5716653902061297 4.453117576534254 5.135972800603594 0.9660014731386156 0.3290604174592388 0.0297797332779157 0.3007677906227077 0.1588529428511447 0.0333870553509734 0.0264828345654996 +Positive regulation of cell cell adhesion 10 33 1.9979466533992856 0.0457224439759669 6.548543689320389 29.79126213592233 0.2392641305343646 0.6381877105722645 3.259798197270223 3.572429669961151 0.7925488926612984 0.3104905639319101 0.0302529000694082 0.4544030019669794 0.3386746096836965 0.0109452146899952 0.0403515594580251 +Receptor recycling 3 8 1.9949310109193472 0.0460504047318126 1.83252427184466 7.075242718446602 0.2017018942761934 0.4536082228606722 1.6905248328776263 1.154000508707628 1.0635166063679875 0.2938337757297349 0.0195634506709255 1.0 0.2223047329091382 0.0242110622206542 0.0351238878380088 +Macrophage activation 3 7 1.993343192573766 0.0462238797866805 2.2135922330097086 6.866504854368932 -0.063381422560026 0.4721182263981376 1.4457872208921387 1.8783757746913443 1.04840992449182 0.2953484668101589 0.0612241796762722 0.0135379522122687 0.048990890514732 0.0118572988629309 0.1028731839020021 +Endomembrane system organization 56 162 1.99159439602283 0.0464155787462903 47.08980582524272 169.73058252427185 0.8987911429216844 0.5600148744834964 15.914797198368843 20.49740065572335 1.4161383035869868 0.4170367608227654 4.080464812169696e-05 0.5601360273234894 0.1682025331533056 0.001150982989544 4.582393799923662e-06 +Regulation of metallopeptidase activity 2 5 1.9869343385763656 0.0469296737169575 1.1237864077669903 3.3106796116504853 -0.0060651105555091 0.6037729146711031 0.968793280528811 0.619726313122614 0.9066188864895364 0.3211850264984928 0.0085378879713771 1.0 0.1008375048293403 0.027832231049335 0.0140126286640228 +Cytokine production involved in inflammatory response 1 7 1.9863094248587263 0.0469989767750314 1.6844660194174756 6.915048543689321 0.5526695518877155 0.4572127495678942 1.5208746385948606 1.410799796429201 0.9262620288568464 0.3010153054171438 0.2384865797430082 0.1049896535105009 0.0202898922491691 0.1060727287920157 0.3080842130268088 +Regulation of mitochondrion organization 12 42 1.9828216963311327 0.0473873496344927 12.08980582524272 45.08252427184466 0.8217268052205459 0.4563186211764868 4.409741308614158 5.146210353910189 1.120993905462196 0.3778427085178187 0.0005310068262162 0.0993430224952972 0.2890592178487741 0.018133097015229 0.0027401058887407 +Intestinal absorption 3 9 1.9823704092283732 0.0474377989332237 1.7354368932038835 8.587378640776699 0.5171971357504386 0.4141116500991276 1.4895775622567284 1.230532256111229 1.0157231952918233 0.2848944302917708 0.0025369657709893 1.0 1.0 0.0498779046475234 0.0048822579474643 +Endoplasmic reticulum tubular network organization 5 10 1.9801378706541508 0.0476880387843556 4.150485436893204 10.555825242718448 0.8961707031484618 0.3171343629503343 2.1669796342432037 1.8339543060404635 1.2935176897309475 0.3199619326088047 0.0041482574964162 0.0786913117950012 0.0113213926532688 0.062605312422627 9.937036022358197e-05 +Regulation of leukocyte degranulation 2 5 1.9793421930112156 0.0477774921611771 1.6699029126213591 6.470873786407767 0.5853711877145334 0.3457823611194687 1.4305158925119918 1.701406104268744 1.0992219708926214 0.2597166324139169 0.0574232775214491 1.0 1.0 0.0983610682747182 0.088385561156941 +Mitochondrial calcium ion homeostasis 4 9 1.9749447871363248 0.0482744140623425 4.62621359223301 10.509708737864075 0.2790428491871666 0.3774917598770124 2.1634860921400008 1.7383182679254283 1.294226020505384 0.3175561312397286 0.5807156750900031 1.0 1.0 1.0 0.017002584405276 +Regulation of leukocyte mediated immunity 8 29 1.968712794016767 0.0489860812825597 7.247572815533981 30.390776699029125 0.1116130068646695 0.6358782484063592 3.3590724754287953 3.498295337807405 0.8071171599029437 0.3154401916393654 0.0187062424960157 0.3807425591661329 0.6174131336935595 0.0101243331138963 0.0216227850680513 +Positive regulation of protein localization to membrane 7 27 1.9686511912475089 0.0489931597758912 6.842233009708738 28.00242718446602 0.1550235383369629 0.7260641052542587 2.930731520743132 3.909472431326232 0.6015798181817977 0.2778032269137012 0.1003256595218385 0.3175327074700926 0.5351022899588459 0.2995832679952916 0.0882575787179951 +Amino acid import 5 7 1.966193636164003 0.0492762473103953 3.441747572815534 8.407766990291263 0.4366482113195755 0.401453661361528 1.9997584452111057 1.165331680805512 1.104576970757323 0.3040222614424157 0.329551311335148 1.0 0.2445730022705269 0.5094216597603356 0.4145551447304083 +Lipid storage 7 19 1.9653198396767244 0.0493772307418713 4.543689320388349 16.905339805825243 0.2970217553985043 0.3661937485285719 2.202279044729986 2.0116820549871304 1.1851757279860726 0.2726034839593525 0.0015490386775862 1.0 0.4129317333780675 0.0438041643494559 0.0047453897441578 +Regulation of toll like receptor signaling pathway 3 9 1.9616229977872863 0.0498063927366734 2.587378640776699 9.50485436893204 0.9772136844316576 0.3297728067967737 1.666236944633112 1.8466647258935645 0.9012634534298872 0.2761306672489575 0.2412275844301856 1.0 0.0614247268920475 0.2707185745648809 0.1451121707049519 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..26335d653809845783e6aa10100e8c394217313a --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 6469, + "title": "Average number of proteins per term", + "value": 18.711547379811407 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ceca27e99bc9bb6df9e87417f774e2bf36ac0dfb --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d53c88f373a6b73ca3744308cd9ac48810cc7341 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,2080 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cellular ion homeostasis 0.640645609913495 4.620879315615814 3.821170183826439e-06 0.0244161797108308 0.0247191499191797 88 Q9HC07,P55011,P09601,P62942,P05023,Q8N511,Q9Y6M7,P04920,Q15043,Q96TC7,P05067,Q96A33,Q8NEW0,Q96PU5,Q16891,P02786,Q93050,Q8IYU8,P50897,Q9HD20,P0DP25,Q9BPX6,P20020,Q9P0T7,Q92544,P06756,O75787,P16615,Q04656,P07686,Q7L0J3,Q15904,Q14964,Q92581,P54709,Q9Y487,O75503,P51790,O76024,P51149,O95202 41 +Ion homeostasis 0.5846598461491935 3.914336275447964 9.065322410251042e-05 0.4437081928860713 0.1496042476400064 103 Q9HC07,P55011,P09601,P62942,P05023,Q8N511,Q9Y6M7,P04920,Q15043,Q96TC7,P05067,Q96A33,Q8NEW0,Q96PU5,P30519,Q16891,P02786,Q93050,Q8IYU8,P50897,Q9HD20,P0DP25,Q9BPX6,P20020,Q9P0T7,Q92544,P06756,O75787,P16615,Q04656,P07686,Q7L0J3,Q15904,Q8NE01,Q14964,Q92581,P54709,Q9Y487,O75503,P51790,O76024,P51149,O95202 43 +Membrane lipid metabolic process 0.765258702425206 3.695454578298417 0.0002194937196204 0.7583006607729255 0.236650812037492 45 O95470,Q99519,P07602,Q99805,P04062,Q8NCC3,P04066,P06280,Q9NRX5,P50897,Q99735,Q9H490,Q92484,Q13510,P16278,P06865,Q06136,Q96G23,Q8TCT0,P07686,Q9H2C2,P17900,Q92643,P27544,Q9NZJ7,Q8NBX0,Q9P035,O15269,Q16739,Q9NZ01 30 +Anion transport 0.6296958476656894 3.632707465043482 0.0002804629177015 0.8370919073836831 0.2591878020873451 70 Q96QD8,P55011,P45880,P05141,Q08722,P51798,Q9Y6M7,P04920,Q9C0H2,P07602,P21796,Q9HC21,Q9Y619,Q9H0H5,Q8TB61,P98164,Q15042,P08195,Q6NUK1,P30825,Q7L0J3,Q92581,Q9H813,Q9H2D1,Q9NZJ7,P54105,P12235,P12236,Q9UHG3,Q9UBX3,P51790,P11166,Q4KMQ2,Q9Y277 34 +Sphingolipid metabolic process 0.7791485005182334 3.5704083087971186 0.0003564252052326 0.9003534304320755 0.2622749561876287 35 O95470,Q99519,P07602,Q99805,P04062,Q8NCC3,P06280,Q9NRX5,P50897,Q92484,Q13510,P16278,P06865,Q06136,Q96G23,Q8TCT0,P07686,Q9H2C2,P17900,P27544,Q9NZJ7,O15269,Q16739,Q9NZ01 24 +Ceramide metabolic process 0.7958098597746728 3.514593311343483 0.0004404279101235 0.9421415490775435 0.2622749561876287 22 P04062,Q8NCC3,P06865,Q96G23,P06280,Q8TCT0,P07686,Q99519,O15269,Q16739,P17900,Q99805,P27544,Q13510 14 +Metal ion homeostasis 0.5642859871630106 3.512276117586538 0.0004442861519098 0.9435683870622344 0.2622749561876287 78 Q9HC07,Q14344,P55011,P09601,P62942,P05023,Q8N511,Q15043,Q96TC7,P05067,Q96A33,Q8NEW0,Q96PU5,P30519,Q16891,P17612,P02786,Q8IYU8,Q9HD20,P0DP25,Q9BPX6,P20020,P06756,P16615,Q04656,P07686,Q7L0J3,Q15904,Q8NE01,P04899,P61421,P54709,Q9Y487,O60826,O76024,O95202 36 +Endocytosis 0.5614317214393291 3.5112666012626863 0.0004459768925744 0.94418251104314 0.2622749561876287 120 P20339,P05556,P62820,Q9NX40,Q08431,P51148,P05067,Q96PU5,Q08380,O15118,P02786,P61020,P98155,P27824,O00560,P14672,P50897,Q92673,P0DP25,P20645,P01130,Q9BZG1,P06756,P98164,Q9UBG0,O15126,Q7Z6M1,Q06481,Q99523,Q9NPF0,P49815,Q14108,Q5KU26,P51809,Q9H223,O15260,Q8WTV0,O75955,P57105,O00429,P11717,Q07954,P51790,Q4KMQ2,Q9UBF8,Q9H4M9,P51149 47 +Liposaccharide metabolic process 0.790191505962623 3.4744400915953633 0.0005119206619499 0.9635736437502916 0.2712610583482661 21 P04062,Q9H490,P16278,P06865,P04066,P06280,Q8TCT0,P07686,Q99519,Q16739,Q92643,P17900,Q99805 13 +Lipid localization 0.5647991382752298 3.449138187161247 0.000562378824831 0.9737227563985472 0.2712610583482661 77 P61916,Q9BUR5,P04114,P07602,Q14534,P04062,O15118,P98155,Q99720,Q14849,Q9Y6B6,P01130,P06756,P07686,Q14108,Q9H2C2,P17900,P35790,P23786,Q9NZJ7,O15260,Q8WTV0,Q9NV96,Q07954,P11166,Q4KMQ2,Q86Y82,Q16739,Q9H4M9,P31751,Q9BQE5 31 +Aminoglycan metabolic process 0.877166471214687 3.4216029492006403 0.000622531518569 0.9821973940371808 0.2712610583482661 15 P54802,P16278,P06865,P04066,Q9NX62,P07686,Q7LGA3,O43505,P15586,Q9Y251 10 +Cellular monovalent inorganic cation homeostasis 0.7707545726502858 3.4187967776715076 0.0006289868411228 0.982925959345773 0.2712610583482661 28 Q9HC07,P55011,P05023,Q9Y6M7,Q8N511,P04920,Q96PU5,Q93050,P50897,Q9P0T7,Q92544,O75787,Q15904,Q14964,Q92581,P54709,Q9Y487,O75503,P51790 19 +Regulation of cellular ph 0.7591348772649293 3.3094680032355845 0.0009347344924277 0.9976412542637192 0.3328304963685611 24 Q9HC07,Q9P0T7,Q92544,O75787,Q9Y487,Q93050,O75503,Q9Y6M7,Q8N511,Q15904,Q14964,P51790,P04920,P50897,Q92581 15 +Regulation of ph 0.7591348772649293 3.3094680032355845 0.0009347344924277 0.9976412542637192 0.3328304963685611 24 Q9HC07,Q9P0T7,Q92544,O75787,Q9Y487,Q93050,O75503,Q9Y6M7,Q8N511,Q15904,Q14964,P51790,P04920,P50897,Q92581 15 +Monovalent inorganic cation homeostasis 0.7448435406148408 3.2913151691490903 0.0009972012248093 0.9984259656144042 0.3328304963685611 31 Q9HC07,P55011,P05023,Q9Y6M7,Q8N511,P04920,Q96PU5,Q93050,P50897,Q9P0T7,Q92544,O75787,Q15904,Q14964,P04899,Q92581,P54709,Q9Y487,O75503,P51790,P51149 21 +Anion transmembrane transport 0.7128213415021313 3.2844215062127806 0.0010219195980458 0.9986587832233204 0.3328304963685611 43 P55011,P45880,P05556,P05141,P51798,Q9Y6M7,O75915,P04920,P21796,O60831,Q9HC21,Q9Y619,Q8TB61,P98164,P08195,P30825,Q92581,Q9H2D1,P12235,P12236,Q9UHG3,Q9UBX3,P51790,Q4KMQ2,Q9Y277 25 +Carbohydrate derivative transport 0.783527655520222 3.2824749219345857 0.0010290013800233 0.9987189011708244 0.3328304963685611 18 P12235,P61916,L0R6Q1,P12236,Q8TB61,Q8WTV0,P98155,P05141,Q9HC21,Q6NUK1,Q08722,P07602,O00400,Q9NZJ7 14 +Vesicle organization 0.506567827162301 3.183580381925955 0.0014546571839553 0.9999186726556164 0.4277353328639536 91 Q6IAA8,Q13501,O60499,Q5SQN1,P62820,Q9BTU6,Q13277,Q9NR31,P61020,Q9H4A5,O15400,O00560,P14672,Q9Y6B6,Q9UNK0,Q9P0T7,Q9H9H4,Q9BZG1,Q99523,Q14964,Q14108,Q9HCU5,Q92692,P49755,O95249,Q13190,P51809,Q8WUM4,P51790,P08754,Q15363,Q86Y82,P51149,Q96CW1,P31751 35 +Establishment of protein localization to membrane 0.515526460224045 3.1426941296312227 0.001674006669132 0.9999803655190412 0.4512145476089787 80 Q9NS69,Q8N4V1,Q15070,Q9Y512,O60725,Q9P0J0,Q99442,Q13277,Q96A33,O15118,P40855,P43307,Q9H4A5,O00560,P0DP25,Q9HD20,Q53H12,Q9H9H4,Q15042,P00533,Q15904,Q15629,P51149,P31751 24 +Organophosphate ester transport 0.7197803398318202 3.0972267597521723 0.0019534038613409 0.9999967889990188 0.4540461048203612 28 P61916,Q8TB61,P12235,Q8WTV0,P12236,Q9NV96,Q08722,Q9HC21,Q6NUK1,Q9H2D1,Q4KMQ2,Q14108,P01130,Q9BSK2 14 +Glycosphingolipid metabolic process 0.8696938292757098 3.0954320892493654 0.001965263709224 0.9999970265861212 0.4540461048203612 12 P16278,P06865,P06280,Q8TCT0,P07686,Q99519,Q16739,P17900,Q99805 9 +Membrane lipid catabolic process 0.8282735644842204 3.0679721840305554 0.0021551667786359 0.9999991317784692 0.4659122982159761 14 P04062,P06865,P04066,P06280,P07686,O95470,Q99519,P50897,P17900,Q99735,Q13510 11 +Transmembrane transport 0.5835790710643961 3.067210117331637 0.0021606691832554 0.9999991622038032 0.4659122982159761 211 Q9NS69,L0R6Q1,O96008,P62942,O60830,P05556,O75915,Q9C0H2,Q99442,P05067,O60831,Q99595,Q8NEW0,O43808,P17612,Q8TB61,Q06481,O14678,Q07820,Q99523,P30825,Q7L0J3,P56134,Q9H2D1,Q9BSK2,P49755,P61421,O75381,P12235,P12236,Q9NV96,Q9UBX3,Q9HC07,O75844,Q16625,P45880,Q7KZN9,P21796,O14925,Q9Y619,Q9UDW1,Q9HD20,P06756,P98164,Q13423,P16615,Q04656,Q8NE01,Q92581,Q15629,Q9Y251,Q03518,Q9UHG3,P51790,P38435,P11166,Q4KMQ2,Q9Y277,O95202,P31751,P52789,Q96QD8,O75964,P39210,Q70HW3,Q8N4V1,P51798,P04920,Q8IUH4,Q96PU5,P04062,Q8NHS3,Q9HC21,P14672,O95831,P0DP25,Q6P4A7,P08195,Q6NUK1,P23786,Q8WTV0,P13073,P36543,P55011,P05023,P05141,Q9Y6M7,Q15526,Q15043,Q8IYU8,Q9BPX6,P20020,P03915,P00403,P54709,Q3ZCQ8,Q8IXU6,O00400 98 +Amyloid precursor protein metabolic process 0.7179159176805742 3.04188591831998 0.0023510097892414 0.999999756119693 0.4878767353620856 22 Q15392,P62942,O95197,Q92542,P35610,Q14254,Q9Y287,P15260,Q92673,Q9NQX7,Q9NQC3,Q96P70 12 +Inorganic anion transport 0.7099016010970293 3.0247019882653063 0.0024887822332584 0.999999900190272 0.4878767353620856 27 Q9H0H5,P54105,P55011,Q9Y277,P45880,Q9UHG3,P51798,Q9Y6M7,Q9UBX3,P51790,P04920,Q9C0H2,Q4KMQ2,P21796,Q9H813 15 +Ion transmembrane transport 0.5396468779640349 3.001992923664626 0.0026821841051742 0.9999999715284366 0.4957442564677853 151 Q9HC07,O75844,P55011,O75964,P45880,P62942,Q70HW3,P05556,Q8N4V1,P51798,O75915,Q7KZN9,P05141,P05023,Q9Y6M7,Q9C0H2,P04920,P21796,Q8IUH4,Q15526,Q15043,P05067,O60831,Q96PU5,Q8NEW0,O43808,Q9HC21,Q8IYU8,Q9Y619,Q9UDW1,Q9HD20,P0DP25,Q9BPX6,Q6P4A7,P20020,P03915,P06756,Q8TB61,P98164,Q13423,P08195,P16615,Q04656,P30825,P00403,Q92581,Q9H2D1,P54709,P12235,P12236,Q9UHG3,Q9UBX3,P51790,Q4KMQ2,Q9Y277,O95202,O00400,P13073,P36543 59 +Cellular homeostasis 0.5229228502312481 2.9478611097999945 0.003199807916737 0.9999999990094348 0.5521756873414189 135 Q9HC07,P52789,P55011,P09601,P62942,P05023,Q8N511,Q9Y6M7,P04920,Q15043,Q96TC7,P05067,Q96A33,Q8NEW0,Q96PU5,Q16891,P17612,P02786,Q93050,Q8IYU8,P50897,Q9HD20,P0DP25,Q9BPX6,Q9NQC3,P20020,Q9P0T7,Q92544,P06756,O75787,P16615,Q04656,P07686,Q7L0J3,Q15904,Q14964,Q92581,P10253,P54709,P54105,Q9Y487,O75503,P09622,P51790,O76024,Q9BWH2,P51149,Q4KMQ2,O95202 49 +Glycoprotein metabolic process 0.6071986705698376 2.9348775244337957 0.0033367936570827 0.9999999995928388 0.5521756873414189 59 Q9HC07,P04843,Q9BT22,P62820,Q9Y287,Q2TAA5,Q7LGA3,Q99805,Q9H9S5,O15118,Q9H0U4,P35610,Q10472,Q9BXS4,O00754,Q9NQX7,P33908,P46977,Q04656,Q86SF2,Q92542,Q10471,P26572,O43505,Q9Y251,O00462,Q9BV10,Q9NX62,Q8WVQ1 29 +Lytic vacuole organization 0.6929582214168455 2.914836260051152 0.0035587520179893 0.9999999999036108 0.5521756873414189 27 Q9HC07,P04062,P54802,Q6IAA8,Q9P0T7,O75787,Q8NHS3,O75503,Q8N511,P42345,P07686,Q14964,O14773,P11117,P50897,Q14108,P51149,P10253 18 +Antigen processing and presentation of peptide antigen 0.8135005565744194 2.9009969001158176 0.0037197755811793 0.9999999999661164 0.5521756873414189 13 P10321,Q99538,Q9UIQ6,Q03518,P04439,Q9NZ08,Q9Y6B6 7 +Divalent inorganic cation homeostasis 0.6337188325544348 2.8698674088725284 0.0041064395296095 0.9999999999972496 0.5708865378790501 50 Q9HC07,P62942,Q15043,Q96TC7,Q96A33,P05067,Q8NEW0,Q16891,Q8IYU8,P0DP25,Q9BPX6,Q9HD20,P20020,P06756,P16615,P07686,Q7L0J3,Q8NE01,O76024,O95202 20 +Inorganic ion transmembrane transport 0.4927421341694107 2.843196150325774 0.004466357356416 0.9999999999997348 0.5708865378790501 109 Q9HC07,P55011,O75964,P62942,P05023,Q8N4V1,P05141,P51798,Q9Y6M7,Q7KZN9,P21796,Q8IUH4,Q15526,Q15043,Q96PU5,Q8IYU8,Q9UDW1,Q9HD20,P0DP25,Q9BPX6,P20020,P03915,P06756,Q13423,P08195,P16615,Q04656,P00403,Q92581,P54709,P12235,Q9UHG3,Q9UBX3,P51790,Q4KMQ2,O95202,O00400,P13073,P36543 39 +Entry into host 0.6637954720280564 2.8148171885566855 0.0048804988276642 0.999999999999982 0.5708865378790501 36 Q9Y624,P11279,P06756,O15118,P02786,P35613,Q8WTV0,P08195,Q92692,P00533,P15529,P01130,Q9BTY2,P07237,Q14108,Q96J02,P07858,O14786 18 +Glucose import 0.7937534979196833 2.799617592045597 0.005116317766225 0.999999999999996 0.5708865378790501 13 P52789,Q16625,Q06481,Q99523,P11166,P31751 6 +Amyloid precursor protein catabolic process 0.7000790519029583 2.788925471477661 0.0052883233143712 0.9999999999999988 0.5708865378790501 18 Q15392,P62942,O95197,Q92542,Q14254,Q92673,P15260,Q9NQC3,Q96P70 9 +Protein targeting 0.4818097725850873 2.785965180146889 0.0053368604099131 0.9999999999999992 0.5708865378790501 102 Q9NS69,Q8N4H5,O96008,O60830,O60725,Q9Y512,Q9P0J0,Q99595,Q9Y5M8,P40855,P43307,O00560,O14925,O95831,Q92673,P20645,P33908,Q9H9H4,Q99523,Q15005,Q14108,Q15629,P55786,Q3ZCQ8,P57105,P51149,P31751 27 +Lysosomal protein catabolic process 0.9001857399214812 2.781307962512531 0.005414035129764 0.9999999999999994 0.5708865378790501 8 P04062,P98164,Q8N511,Q07954,O14773,P01130 6 +Protein catabolic process in the vacuole 0.9001857399214812 2.781307962512531 0.005414035129764 0.9999999999999994 0.5708865378790501 8 P04062,P98164,Q8N511,Q07954,O14773,P01130 6 +Regulation of vesicle mediated transport 0.4932027354529285 2.780089385935714 0.0054343937663012 0.9999999999999996 0.5708865378790501 116 P20339,P09601,Q9P2W9,Q08722,Q08431,P51148,Q9NR31,P05067,Q96PU5,P51151,O14786,P61020,O00560,P50897,Q92673,P0DP25,Q9Y6B6,P06756,Q15042,Q06481,P16615,P04899,P49815,Q9HCU5,P11233,P51809,Q9H223,Q8WTV0,Q8WUM4,Q9H4M9,O75955,P57105,Q6NUQ1,Q07954,Q12907,Q4KMQ2,P31751,P11279,P51149,Q96CW1,Q4J6C6 41 +Amyloid beta formation 0.8055484173246468 2.778865974655551 0.0054549026746686 0.9999999999999996 0.5708865378790501 12 O95197,Q9NQC3,Q92673,P15260 4 +Vacuole organization 0.6181936511563478 2.774182276761573 0.0055340661398841 0.9999999999999998 0.5708865378790501 51 Q9HC07,P20339,Q6IAA8,Q9Y4P8,Q8N511,P62820,P54802,P04062,Q8NHS3,Q9H0U4,P42345,P50897,Q9P0T7,Q9BZG1,O75787,Q15042,P16615,P07686,Q14964,P11117,Q14108,P10253,O75503,O14773,Q86Y82,P51149 26 +Golgi vesicle transport 0.4942096772364802 2.772574518357451 0.0055614784364446 0.9999999999999998 0.5708865378790501 118 O43731,O60499,Q9P2W9,P51572,P62820,O15127,O00743,P54920,Q9Y282,Q9NR31,P40616,Q92572,P24390,Q9H4A5,Q6DD88,Q9H0U4,O95070,Q92673,P49257,Q9Y6B6,Q9UID3,O15258,Q8TBA6,Q969X5,Q9BZG1,O15126,Q9Y3B3,Q99523,P61019,Q9HD26,Q9HCU5,P49755,O95249,Q13190,P51809,O15260,O60826,Q6NUQ1,Q12907,Q15363,O14828,P11279,Q8NHH9,Q4J6C6 44 +Cation transmembrane transport 0.4939703327197826 2.7697778578616097 0.0056094535973398 1.0 0.5708865378790501 118 Q9HC07,P55011,O75964,P62942,Q70HW3,Q8N4V1,P05141,P05023,Q9Y6M7,Q7KZN9,P21796,Q8IUH4,Q15526,Q15043,P05067,Q96PU5,Q8NEW0,Q9HC21,Q8IYU8,Q9Y619,Q9UDW1,Q9HD20,P0DP25,Q9BPX6,P20020,P03915,P06756,Q13423,P08195,P16615,Q04656,P30825,P00403,Q92581,P54709,P12235,P51790,Q4KMQ2,O95202,O00400,P13073,P36543 42 +Nucleotide transport 0.7707510429642428 2.7662548188645 0.0056704206815525 1.0 0.5708865378790501 14 P12235,Q8TB61,P12236,P05141,Q9HC21,Q6NUK1,Q08722,O00400,Q9H2D1,Q9BSK2 10 +Membrane lipid biosynthetic process 0.6717458105882634 2.762490520314496 0.0057362227488233 1.0 0.5708865378790501 25 P04062,Q8NBX0,Q9P035,Q9H490,Q06136,Q96G23,O43292,O95470,Q16739,O15269,Q92643,Q99805,P27544,Q13510 14 +Antigen processing and presentation of peptide antigen via mhc class i 0.8132564743299106 2.743159092547587 0.006085119590083 1.0 0.5779130836679023 11 P10321,P04439,Q9UIQ6,Q03518,Q9NZ08,Q9Y6B6 6 +Ph reduction 0.7816829546299966 2.737010424077181 0.0062000328389817 1.0 0.5779130836679023 13 Q9P0T7,O75787,Q9Y487,O75503,Q93050,Q8N511,P51790,Q14964,P50897,P51149 10 +Import across plasma membrane 0.6710693088520056 2.736518111572141 0.0062093176799957 1.0 0.5779130836679023 19 P54709,P98164,P55011,P08195,P05023,P05556,O75915,P30825,P11166,Q92581,Q15043,P31751 12 +Oligosaccharide metabolic process 0.9168818318335588 2.7120883604433637 0.0066860767391569 1.0 0.5779130836679023 7 O00462,P06280,Q99519,P17900,P10253 5 +Inner mitochondrial membrane organization 0.6842520604001258 2.6918993000188296 0.0071046393533795 1.0 0.5779130836679023 18 Q16891,Q9H3K2,Q9BUR5,Q9P0J0,Q9Y512,Q13505,Q6UXV4,O60313,Q9NVH1,O95202,Q5XKP0 11 +Glycolipid catabolic process 0.8758794704588945 2.672762858996196 0.0075229410195389 1.0 0.5779130836679023 8 P06865,P04066,P06280,P07686,Q99519,P17900 6 +Sphingolipid biosynthetic process 0.6980911800495336 2.6589362698237724 0.007838778920179 1.0 0.5779130836679023 17 P04062,Q9P035,Q06136,Q96G23,O95470,O15269,Q16739,Q99805,P27544,Q13510 10 +Organic anion transport 0.6235695886935139 2.6548039523520583 0.0079354512507257 1.0 0.5779130836679023 44 Q96QD8,P55011,P05556,Q08722,P05141,Q9Y6M7,O75915,P04920,P07602,O60831,Q9HC21,Q9Y619,Q8TB61,P98164,Q15042,P08195,Q6NUK1,P30825,Q7L0J3,Q9H2D1,Q9NZJ7,P12235,P12236,Q9UBX3,P11166,O00400 26 +Vitamin transport 0.8086445607771509 2.6535998452907 0.0079638205825396 1.0 0.5779130836679023 10 P04062,P98164,Q8WTV0,Q9HC21,P38435,Q9NPF0,P11166,Q9H2D1 8 +Amyloid beta metabolic process 0.7489514215700591 2.64889432598634 0.0080755578259359 1.0 0.5779130836679023 14 O95197,Q9NQC3,Q92673,P15260 4 +Membrane protein proteolysis 0.7925519670312141 2.6405892463365603 0.0082761991647857 1.0 0.5779130836679023 11 Q9NZ08,Q8TCT8,Q92542,Q16740 4 +Regulation of glycoprotein metabolic process 0.7902945856437659 2.629325531107603 0.0085554419607489 1.0 0.5779130836679023 11 Q9H0U4,Q92542,Q9BXS4,P62820,Q9Y287,Q99805,Q9NQX7 7 +Ceramide catabolic process 0.8632872234765215 2.61594387670795 0.0088981181968121 1.0 0.5779130836679023 8 P04062,P06865,P06280,P07686,Q99519,P17900 6 +Mitochondrial membrane organization 0.6193762759293979 2.604109288505991 0.0092113379123854 1.0 0.5779130836679023 43 P52789,Q9NS69,P45880,P05141,Q9BUR5,Q15070,Q9P0J0,Q9Y512,Q6UXV4,Q13505,Q16891,Q9NVH1,P0DP25,Q8IWA4,Q9H3K2,P12235,Q3ZCQ8,O60313,O95202,Q5XKP0 20 +Lipoprotein metabolic process 0.6476534872372524 2.602843636887792 0.0092454109562387 1.0 0.5779130836679023 25 P04062,P06756,Q15042,Q5HYI8,P04114,Q16739,P50897,Q8IUH4,Q9H490,P01130,Q9BQE5 11 +Glycoprotein biosynthetic process 0.5999221258421553 2.6025633560795907 0.0092529716874607 1.0 0.5779130836679023 50 Q9HC07,P04843,Q9BT22,Q9Y287,Q2TAA5,Q7LGA3,Q99805,Q9H9S5,O15118,P35610,Q10472,Q9BXS4,Q9NQX7,P33908,P46977,Q04656,Q86SF2,Q92542,Q10471,P26572,O43505,Q9BV10,Q8WVQ1 23 +Cytochrome complex assembly 0.7801113820116374 2.5783147104066875 0.0099283529711857 1.0 0.5779130836679023 11 Q7KZN9,Q15070,P53701,Q9Y2R0,Q6DKK2,Q9BSK2 6 +Regulation of plasma lipoprotein particle levels 0.7015103700922711 2.572159688935646 0.0101066262677873 1.0 0.5779130836679023 16 P17612,Q8WTV0,P09601,P98155,P38571,P04114,Q9H4M9,Q9Y2B0,P01130 9 +Vitamin transmembrane transport 0.8822422240634827 2.5610398838402526 0.0104359374816547 1.0 0.5779130836679023 7 P04062,P98164,Q9HC21,P38435,Q9H2D1 5 +Chloride transport 0.7482527478353906 2.561024257873577 0.0104364068816875 1.0 0.5779130836679023 13 P54105,Q9UHG3,P51798,P51790,Q9C0H2,Q4KMQ2,Q9H813 7 +Vacuolar acidification 0.8192838646182943 2.556011112550999 0.0105879737478018 1.0 0.5779130836679023 9 Q9P0T7,O75787,O75503,Q93050,Q8N511,P50897 6 +Proteoglycan metabolic process 0.8808813718319902 2.55504787068999 0.010617319502854 1.0 0.5779130836679023 7 Q7LGA3,Q99805,Q9NX62,Q9Y251 4 +Regulation of amyloid precursor protein catabolic process 0.6978154570404553 2.5505790096844625 0.0107544144669562 1.0 0.5779130836679023 16 O95197,Q9NQC3,Q92673,P15260 4 +Receptor mediated endocytosis 0.5614592381868799 2.540132297862848 0.0110810543889603 1.0 0.5779130836679023 59 P20339,P06756,P98164,P02786,P98155,P27824,Q7Z6M1,O75955,O00560,P11717,Q07954,P50897,Q92673,Q14108,P20645,P01130,P05067 17 +Carbohydrate transmembrane transport 0.69510821902413 2.534731126632505 0.0112533663419811 1.0 0.5779130836679023 16 P52789,Q16625,Q06481,Q99523,P11166,P31751 6 +Mucopolysaccharide metabolic process 0.8450478016158052 2.5329236956097945 0.0113115573302535 1.0 0.5779130836679023 8 P16278,O43505,Q9NX62,P15586 4 +Protein localization to vacuole 0.6765485491761898 2.5292629535065387 0.0114302355890214 1.0 0.5779130836679023 17 Q9H9H4,Q99523,Q14108,Q92673,P20645,Q9NQC3 6 +Antigen processing and presentation of exogenous peptide antigen 0.9003697749824136 2.527728150640985 0.0114803205871003 1.0 0.5779130836679023 6 Q99538,Q9UIQ6,P04439 3 +Metal ion export 0.8420866648299574 2.51936442824849 0.0117566904981309 1.0 0.5779130836679023 8 P05023,Q04656,Q4KMQ2,P0DP25,O95202,P20020 6 +Regulation of t cell proliferation 0.6564054447228616 2.5183901287994632 0.011789265858495 1.0 0.5779130836679023 18 P10644,P02786,P04439,P30825,P15529,Q5ZPR3 6 +Regulation of lysosomal protein catabolic process 0.8976246321720872 2.515929136604918 0.0118719050105797 1.0 0.5779130836679023 6 Q07954,P04062,P01130,P98164 4 +Regulation of protein catabolic process in the vacuole 0.8976246321720872 2.515929136604918 0.0118719050105797 1.0 0.5779130836679023 6 Q07954,P04062,P01130,P98164 4 +Lipoprotein biosynthetic process 0.672375097860622 2.5039056494714775 0.012283078477719 1.0 0.5779130836679023 17 P04062,Q15042,O43292,Q5HYI8,P04114,Q16739,Q9H490,Q8IUH4,Q92643 9 +Locomotory behavior 0.6288872969614981 2.498747513092223 0.0124633073882587 1.0 0.5779130836679023 29 P54802,O75844,O15118,Q04656,P07686,P10253,P50897,P05067 8 +Cristae formation 0.8067439497477901 2.4964666512517137 0.0125437462862509 1.0 0.5779130836679023 9 Q16891,Q9BUR5,Q9Y512,Q9NVH1,O95202,Q5XKP0 6 +Regulation of lysosomal lumen ph 0.8672177923764501 2.4946396938818616 0.0126085085949687 1.0 0.5779130836679023 7 Q9P0T7,Q9HC07,O75503,Q8N511,P50897 5 +Circulatory system process 0.5127862358572607 2.4807380852878524 0.0131110671997285 1.0 0.5779130836679023 69 O75844,Q96QD8,Q16625,P09601,P55011,Q9UIQ6,P05023,Q9HB40,Q14126,Q96PU5,P02786,P17612,P42785,P42345,P14672,Q9NZ08,P0DP25,P20020,O75787,P98164,P00387,P16615,P30825,Q02487,P04899,O94813,P10253,Q15758,P42892,O00429,Q07954,P11166 32 +Antigen processing and presentation of exogenous antigen 0.8025645620879995 2.476522546349079 0.0132669245330852 1.0 0.5779130836679023 9 Q99538,Q9UIQ6,P04439 3 +Nucleotide transmembrane transport 0.7993404341264733 2.461103057156382 0.0138510573109766 1.0 0.5779130836679023 9 P12235,Q9H2D1,Q9BSK2,Q8TB61 4 +Metal ion transport 0.4500796492075253 2.460058785619926 0.0138914260003382 1.0 0.5779130836679023 97 Q9HC07,O75844,Q96QD8,P55011,P62942,P05023,P05556,Q8N4V1,Q9Y6M7,O15173,P21796,Q8IUH4,Q15043,Q96PU5,Q8NEW0,P02786,Q8IYU8,Q9HD20,P0DP25,Q9BPX6,P20020,P06756,P98164,P08195,P16615,Q04656,Q92581,P54709,O76024,Q4KMQ2,O95202 31 +Vascular transport 0.6979775090783449 2.454949080490537 0.0140904545571383 1.0 0.5779130836679023 15 Q96QD8,P98164,P02786,P14672,P30825,Q07954,P11166 7 +Glycoside catabolic process 0.8786686797588947 2.4339906699967218 0.0149333800073419 1.0 0.5779130836679023 6 P08236,Q9BTY2,P04066,P06280 4 +Macroautophagy 0.4520214516471066 2.4308492331158207 0.0150634812371548 1.0 0.5779130836679023 102 O43633,P20339,Q5T8D3,Q13501,Q86VR2,Q9Y4P8,P09601,Q9Y6I9,P05141,P62820,P21796,P04062,O15118,P17612,O14681,Q93050,Q8NHS3,Q9H0U4,P42345,Q9H9H4,Q15042,P16615,P49815,Q14596,P27544,Q96HY6,P61421,P51809,P12235,Q9Y487,P08754,Q13137,Q86Y82,O15269,P51149,P36543 36 +Positive regulation of locomotion 0.4467826760861408 2.430704124621347 0.0150695148906927 1.0 0.5779130836679023 96 P09601,Q08722,O00592,Q13277,P36896,P05067,O14786,O00560,Q13685,P07942,Q9NQC3,Q13641,P06756,Q99538,Q04656,P00533,O94813,Q96HY6,Q8WTV0,Q15555,P43121,Q4KMQ2,P31751 23 +Vascular process in circulatory system 0.6146375150788244 2.422191026610528 0.0154272385141644 1.0 0.5779130836679023 32 Q96QD8,P98164,P02786,Q16625,P55011,P42892,P14672,P30825,Q9HB40,Q07954,O94813,P11166 12 +Antigen processing and presentation 0.6215547014729152 2.4177863331966343 0.0156152430151788 1.0 0.5779130836679023 22 P04062,P10321,P61020,Q9UIQ6,Q99538,P04439,Q03518,Q9NZ08,Q9Y6B6 9 +Mitochondrial respiratory chain complex assembly 0.6083568949445624 2.4175331001899982 0.0156261127189323 1.0 0.5779130836679023 36 O96000,Q9Y6M9,Q15070,Q9P0J0,Q96CU9,O95831,Q86Y39,O43676,Q6DKK2,Q15526,Q9BSK2,Q9H061,Q9Y2R0,P03886,O75438,O95169,P03915 17 +Inorganic anion transmembrane transport 0.7900068373028736 2.4162977122759677 0.0156792356783188 1.0 0.5779130836679023 9 Q9UHG3,Q9UBX3,P51798,P51790,Q4KMQ2 5 +Cerebellar cortex development 0.7472531321794332 2.411459295888326 0.0158888252908848 1.0 0.5779130836679023 11 P54802,O14949,Q04656,Q5KU26 4 +Purine nucleotide transport 0.7471751328479935 2.411059058206574 0.0159062725374294 1.0 0.5779130836679023 11 P12235,Q8TB61,P12236,P05141,Q08722,Q6NUK1,O00400 7 +Carbohydrate transport 0.6392211682442588 2.4094955886055884 0.0159745891852982 1.0 0.5779130836679023 18 P52789,Q16625,Q06481,Q99523,P11166,P31751 6 +Endoplasmic reticulum to golgi vesicle mediated transport 0.5228841522583313 2.4069747142974394 0.0160852835258127 1.0 0.5779130836679023 65 O43731,Q9P2W9,P51572,P62820,O00743,Q9Y282,Q9NR31,P24390,Q6DD88,Q9H0U4,O95070,Q92673,P49257,Q9Y6B6,Q969X5,Q9Y3B3,P61019,Q9HCU5,Q9HD26,P49755,Q13190,O95249,P51809,Q6NUQ1,Q12907,Q15363,Q8NHH9 27 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.6193373247701143 2.405019222470882 0.0161716151278228 1.0 0.5779130836679023 23 O43731,P35606,O15258,Q969X5,P24390,P49755,Q9H4A5,Q9P2W9,Q6NUQ1,Q12907,Q9Y282,P18085 12 +Protein localization to plasma membrane 0.5001013767322681 2.399824842117676 0.0164029186553567 1.0 0.5779130836679023 70 Q13501,P05556,Q13277,P19022,Q9H4A5,O15400,Q14254,Q9BXS4,Q13641,Q9UNK0,O15258,P00533,Q15904,O00264,Q9Y624,P54709,P35613,Q9H223,O75955,Q07954,Q15363,Q9H4M9,P51149,P31751 24 +Mitochondrial transport 0.4753844768146715 2.394532872807408 0.0166415516237588 1.0 0.5779130836679023 75 P52789,Q9NS69,P12235,Q8N4H5,O75964,P45880,P55786,O60830,P05141,O14925,Q6NUK1,Q9UBX3,Q15070,O95831,Q14849,P23786,Q99595 17 +Protein localization to cell periphery 0.443423322027911 2.39398555341176 0.0166664052247949 1.0 0.5779130836679023 81 Q13501,P05556,Q13277,P19022,Q9H4A5,O15400,Q14254,Q9BXS4,Q13641,Q9UNK0,O15258,P00533,Q15904,O00264,Q9Y624,P54709,P35613,Q9H223,O75955,Q07954,Q15363,Q9H4M9,P51149,P31751 24 +Hormone metabolic process 0.6112819562758206 2.3825406826382833 0.0171936320687142 1.0 0.5779130836679023 30 Q6NUM9,O75844,O75787,P42892,P16870,Q8TC12,P05023,Q9HB40,O95470,Q14849,P08069,P16435,Q53GQ0,Q8NBN7,P07858 15 +Plasma lipoprotein particle clearance 0.7002189347614989 2.3802464256316087 0.017301063883758 1.0 0.5779130836679023 14 Q8WTV0,P09601,P98155,P38571,P04114,Q9H4M9,Q9Y2B0,P01130 8 +Negative regulation of developmental growth 0.7398592980185547 2.3734309351319283 0.0176236886407274 1.0 0.5779130836679023 11 Q99538,Q15375,Q9NQC3 3 +Protein transmembrane transport 0.6126874994507937 2.3657296264355043 0.0179945803949181 1.0 0.5779130836679023 25 P49755,Q9NS69,O96008,O60830,Q07820,Q3ZCQ8,O14925,O95831,P31751,Q99442,Q15629,Q99595,Q9Y251 13 +Adult behavior 0.6139925824963666 2.364849629301791 0.0180373928871286 1.0 0.5779130836679023 20 O75844,O15118,Q92542,P50897,P05067 5 +Regulation of glucose import 0.7785033030137277 2.360732025802938 0.0182389047465845 1.0 0.5779130836679023 9 Q06481,Q16625,P31751 3 +Regulation of cell killing 0.8071795295128429 2.357791685378397 0.0183840061286684 1.0 0.5779130836679023 8 P01889,Q9NUQ9,P04439,O15400,P11279 5 +Localization within membrane 0.4958815112579725 2.3574136047109375 0.0184027369644368 1.0 0.5779130836679023 167 Q9NS69,Q13501,P05556,Q8N4V1,Q96L92,O75915,Q15070,Q9Y512,O60725,Q9P0J0,P07602,Q99442,Q13277,Q99805,Q96A33,O15118,P40855,P43307,Q9H4A5,P19022,Q9HD45,O15400,O00560,Q14254,Q9BXS4,Q92673,Q9HD20,P0DP25,Q9BTX1,Q9UID3,Q53H12,Q13641,Q9UNK0,Q92544,O15258,Q9H9H4,P16870,Q15042,P00533,Q15904,Q15629,O00264,Q9NZJ7,Q9Y624,P54709,P35613,Q9H223,O75955,P57105,Q07954,Q15363,Q9H4M9,P51149,P11233,P31751 55 +Neuron projection guidance 0.6119192245098785 2.354670661054292 0.0185391285096179 1.0 0.5779130836679023 23 Q15375,O15031,P35613,P42892,O94813,O00264,P05067 7 +Aminoglycan catabolic process 0.9222440944881874 2.3536849767788026 0.018588356793088 1.0 0.5779130836679023 5 P54802,P04066,P16278,P15586 4 +Glycosaminoglycan catabolic process 0.9222440944881874 2.3536849767788026 0.018588356793088 1.0 0.5779130836679023 5 P54802,P04066,P16278,P15586 4 +Membrane invagination 0.7230226342043568 2.3521901074380445 0.0186632337068637 1.0 0.5779130836679023 12 Q06481,Q4KMQ2,P51790,Q08431 4 +Neuropeptide signaling pathway 0.9205312723802976 2.346623244304828 0.0189443998135265 1.0 0.5779130836679023 5 Q92673,P16870 2 +Regulation of oxidoreductase activity 0.6290045145433734 2.344083153779997 0.0190739183542167 1.0 0.5779130836679023 18 P00374,Q8WTV0,Q04656,P06280,P00533,Q8TCT9,Q15070,P16435,P04899,P0DP25 10 +Membrane protein ectodomain proteolysis 0.772783612181843 2.332962078867193 0.0196501356791916 1.0 0.5779130836679023 9 Q9NZ08,Q8TCT8,Q92542 3 +Regulation of er to golgi vesicle mediated transport 0.8303539471233294 2.329408399738315 0.0198374405081158 1.0 0.5779130836679023 7 Q9P2W9,Q6NUQ1,Q92673,Q9Y6B6,Q9NR31 5 +Regulation of autophagy 0.4346949164569526 2.3261075003090927 0.0200128165327608 1.0 0.5779130836679023 92 O75844,Q9UPT5,P09601,Q14145,P05141,P10619,P07602,P21796,Q86UE4,P04062,Q9NNW5,O15118,P17612,Q93050,Q8NHS3,P42345,Q9BXS4,Q86UE8,Q9NZ45,Q15042,Q07820,P49815,P27544,P61421,Q9NZJ7,P12235,Q9Y487,Q9HB90,O00429,P08754,Q13137,O15269,P36543 33 +Glycoside metabolic process 0.7704172307090389 2.321445252049409 0.0202628256482151 1.0 0.5779130836679023 9 P08236,Q9BTY2,P04066,P06280 4 +Regulation of leukocyte mediated cytotoxicity 0.8282909237021913 2.3200635117269925 0.0203374418475246 1.0 0.5779130836679023 7 P01889,Q9NUQ9,P04439,O15400,P11279 5 +Positive regulation of cell killing 0.8282909237021913 2.3200635117269925 0.0203374418475246 1.0 0.5779130836679023 7 P01889,Q9NUQ9,P04439,O15400,P11279 5 +Protein localization to lysosome 0.6894286875441165 2.319557059430542 0.0203648510537386 1.0 0.5779130836679023 14 Q14108,Q9NQC3,Q99523,Q92673 4 +Chemical homeostasis 0.4972409852442903 2.3173804587927376 0.0204830158721198 1.0 0.5779130836679023 174 Q9HC07,P52789,Q6IAA8,P61916,P55011,P09601,P62942,P05023,Q8N511,Q9Y6M7,Q9Y6C9,P04114,P04920,Q15043,Q96TC7,P05067,Q96A33,Q8NEW0,Q96PU5,P30519,P04062,O15118,P17612,P02786,Q16891,Q15067,Q93050,P42785,P14672,P35610,P08069,Q8IYU8,P50897,Q9HD20,P0DP25,Q9Y6B6,Q9BPX6,Q9NQC3,P01130,P20020,Q9P0T7,Q8NF37,Q92544,P06756,O75787,Q06481,P16615,Q04656,P07686,Q7L0J3,Q15904,Q8NE01,P04899,Q14964,Q92581,Q16531,P54709,O15260,Q8WTV0,Q9Y487,O75503,Q9P035,P51790,O76024,Q9BWH2,P51149,Q16739,Q9H4M9,O95202 69 +Organic acid transmembrane transport 0.6017434095367794 2.314841555173666 0.0206216048199394 1.0 0.5779130836679023 30 Q96QD8,P98164,Q15758,P08195,O14678,P05556,Q9UBX3,O75915,P30825,P11166,Q9Y619,P31751,P23786,Q9H2D1,O60831 15 +Membrane organization 0.5205614423935581 2.307358081907596 0.0210348660433035 1.0 0.5779130836679023 214 Q15392,Q9NS69,O94901,O75844,P52789,P61916,O14657,P45880,O60499,Q9P2W9,Q8N4V1,Q9BUR5,P05141,Q15070,Q9Y512,Q5SQN1,P04114,Q9P0J0,P62820,Q08431,Q13505,Q13277,Q9NR31,Q96A33,Q16891,O15118,P19022,Q9H4A5,O15400,P14672,Q14254,Q14849,P50897,P0DP25,Q9Y6B6,Q9NVH1,Q9NQC3,Q9UNK0,O15258,P57088,Q06481,P16615,P00533,Q14964,Q8IWA4,Q9HCU5,Q9H2C2,Q15629,Q92692,P50402,Q9NZJ7,O95249,Q13190,Q9H3K2,P51809,P12235,O43760,Q9NV96,O75955,Q3ZCQ8,P51790,Q86XL3,Q15363,Q4KMQ2,O60313,Q86Y82,Q16739,P51149,O95202,Q5XKP0,Q8NHH9,P31751,Q8NFQ8 73 +Regulation of regulated secretory pathway 0.6556871133613652 2.300478416969514 0.021421130680028 1.0 0.5779130836679023 16 P20339,P51809,P09601,Q15042,P16615,P04899,P0DP25,P11279,Q4J6C6 9 +Negative regulation of neuron projection development 0.6221904396649787 2.3001751554115675 0.0214382987740568 1.0 0.5779130836679023 18 Q15375,Q9NQX7,Q9NQC3 3 +Export across plasma membrane 0.8236724966196686 2.299105515248343 0.0214989484074472 1.0 0.5779130836679023 7 P05023,Q4KMQ2,P20020,P0DP25 4 +Cartilage development 0.6997505098895945 2.2987085379882877 0.0215214953825815 1.0 0.5779130836679023 13 O75844,Q04656,Q92896,Q9NX62,P16435,Q96HY6 6 +Mannosylation 0.7657373424537627 2.2986210988092775 0.0215264644000579 1.0 0.5779130836679023 9 O43505,Q9BT22,Q9H9S5,Q9BV10 4 +Phospholipid transport 0.6854053476625522 2.296814174185373 0.021629372631821 1.0 0.5779130836679023 14 P61916,Q9NV96,Q4KMQ2,Q14108,P01130 5 +Vesicle docking 0.6705131857008405 2.2961387615361972 0.0216679486379789 1.0 0.5779130836679023 15 Q13190,O60499,O15400,Q86Y82,Q13277,Q9UNK0 6 +Ion transport 0.5120509893209878 2.29362101916802 0.0218122769735182 1.0 0.5779130836679023 201 Q9HC07,O75844,Q96QD8,P55011,O75964,O96008,P45880,P62942,Q70HW3,P05556,Q08722,Q8N4V1,O75915,Q7KZN9,P51798,P05141,P05023,Q9C0H2,P04920,P07602,O15173,P21796,Q8IUH4,Q15526,Q15043,P05067,O60831,Q96PU5,Q8NEW0,O43808,P02786,Q9HC21,Q8IYU8,Q9Y619,Q9UDW1,Q9HD20,P0DP25,Q9BPX6,Q6P4A7,P20020,P03915,Q9H0H5,P06756,Q8TB61,P98164,Q13423,Q15042,P08195,P16615,Q04656,Q6NUK1,P30825,Q7L0J3,Q8NE01,P00403,Q9Y6M7,Q92581,Q9H813,Q9H2D1,Q9NZJ7,P54709,P51809,P54105,P12235,P12236,Q9UHG3,Q9UBX3,P51790,O76024,P11166,Q4KMQ2,Q9Y277,O95202,O00400,P13073,P36543 76 +Regulation of blood pressure 0.6544060131027178 2.292754961133128 0.021862116337967 1.0 0.5779130836679023 16 O75787,P42892,P09601,Q9UIQ6,P05023,P42785,Q9HB40,Q9NZ08,P20020 9 +Regulation of organic acid transport 0.7346634672401755 2.2863608668639044 0.022233155726641 1.0 0.5779130836679023 10 P55011,Q15042,P05556,Q7L0J3,P31751 5 +Response to ph 0.905452053270018 2.284208713474046 0.0223592677230741 1.0 0.5779130836679023 5 Q99538,P19021,P51798 3 +L amino acid transport 0.7088053385571077 2.2763586487051257 0.0228245525081114 1.0 0.5779130836679023 12 Q96QD8,Q15758,P08195,P05556,O75915,P30825,Q9Y619,O60831 8 +Behavior 0.4595263675882546 2.2752933968814464 0.0228883352918325 1.0 0.5779130836679023 76 O75844,P05067,P54802,P04062,O15118,P98155,P14672,P50897,P01130,Q13641,Q99538,Q04656,Q92542,P00533,P07686,P17900,O00264,P10253,P51790 19 +Lipoprotein localization 0.8411918331833639 2.269591362675395 0.0232323881737541 1.0 0.5779130836679023 6 Q07954,P04114,Q9Y6B6,O15260 4 +Selective autophagy 0.5942562447337768 2.26813912667215 0.0233207282599097 1.0 0.5779130836679023 31 Q13501,Q86VR2,Q9Y4P8,P12235,Q9Y6I9,P05141,Q13137,P49815,O15269,P21796,P51149,P27544,Q96HY6 13 +Cerebral cortex cell migration 0.7070945729428684 2.267186641498347 0.0233788265287571 1.0 0.5779130836679023 12 Q96N66,P00533,O94813,P07942,Q9NQC3 5 +Positive regulation of protein exit from endoplasmic reticulum 0.8405734161937384 2.2668516086918187 0.0233992922073256 1.0 0.5779130836679023 6 Q9Y6B6,Q9NV96,Q9NR31,Q92673 4 +Early endosome to golgi transport 0.8163651650701039 2.265838376991299 0.0234612807279179 1.0 0.5779130836679023 7 O60499,Q13190 2 +Axon development 0.4729595931247583 2.262953722150693 0.0236385421982856 1.0 0.5779130836679023 73 P05556,O14786,P05067,Q15375,P19022,P08069,Q9NQC3,Q06481,Q96G23,O94813,Q92581,O00264,O15031,P00374,P35613,P42892,P10586,O75955,P07196 19 +Steroid metabolic process 0.5072914019631389 2.2568777852489417 0.0240157125086288 1.0 0.5779130836679023 65 Q15392,Q6IAA8,P61916,P05023,O95470,P04114,P05067,Q14534,P04062,O15118,P98155,Q16850,P35610,P08069,Q14849,Q53GQ0,P01130,Q13510,P98164,P38571,P00387,Q15800,Q99538,Q9H2C2,Q14739,Q8WTV0,P14324,P38435,P16435,Q9BQE5 30 +Antigen processing and presentation of endogenous antigen 0.8378656516164442 2.2548451455256338 0.0241430504437996 1.0 0.5779130836679023 6 P04439,Q03518,Q9NZ08,P10321 4 +Antigen processing and presentation of endogenous peptide antigen 0.8378656516164442 2.2548451455256338 0.0241430504437996 1.0 0.5779130836679023 6 P04439,Q03518,Q9NZ08,P10321 4 +Cytosolic calcium ion transport 0.5957619047037762 2.242017126906884 0.0249602654114156 1.0 0.5779130836679023 21 P62942,P16615,Q8IYU8,P0DP25,Q9BPX6,P21796,O95202,P20020 8 +Lysosomal lumen acidification 0.8950131233595728 2.240743133955207 0.025042718357374 1.0 0.5779130836679023 5 Q9P0T7,O75503,P50897,Q8N511 4 +Negative regulation of glycoprotein metabolic process 0.955590506461889 2.2358577381153824 0.0253610914069317 1.0 0.5779130836679023 4 Q9BXS4,Q9Y287 2 +Synapse assembly 0.6288398884649409 2.234730374345176 0.0254350552479958 1.0 0.5779130836679023 17 Q15375,O00560,P05067,O15031 4 +Cellular transition metal ion homeostasis 0.593924218048384 2.230068079883354 0.0257429235437847 1.0 0.5779130836679023 22 Q8NEW0,P02786,P09601,Q9Y487,Q04656,Q8N511,Q15904,P05067 8 +Amyloid beta clearance 0.699538904738664 2.226556269152971 0.0259769443840884 1.0 0.5779130836679023 12 P20339,P98164,Q16850,Q07954,P15260,P01130 6 +Receptor metabolic process 0.5850349796230289 2.2252236941249235 0.0260662249909109 1.0 0.5779130836679023 34 P20339,Q6IAA8,P02786,P42892,Q99538,O75955,O00560,Q07954,Q92673,Q96J02,P01130 11 +Proton transporting two sector atpase complex assembly 0.8907411778785178 2.222894870464264 0.0262228897525131 1.0 0.5779130836679023 5 Q9P0T7,Q15070,Q8N511 3 +Odontogenesis 0.6988051801662459 2.2226000895507947 0.0262427781773479 1.0 0.5779130836679023 12 P04920,P35613,P19021 3 +Intermembrane lipid transfer 0.8058605198105646 2.21778476840654 0.0265695111537351 1.0 0.5779130836679023 7 Q14849,P04114 2 +Response to iron ion 0.829078547432369 2.215766390869397 0.0267075053453786 1.0 0.5779130836679023 6 P02786,P09601 2 +Multi multicellular organism process 0.5866488345980928 2.2131448124316195 0.0268876634513632 1.0 0.5779130836679023 31 Q96QD8,P35613,Q9UIQ6,Q04656,P07686,Q15363,P11166,P07858,P36896,P19021,Q9BQE5 11 +Chloride transmembrane transport 0.8284030482663648 2.2127549122452685 0.0269145473057936 1.0 0.5779130836679023 6 Q9UHG3,Q4KMQ2,P51798,P51790 4 +Sulfur compound transport 0.8039128316649209 2.2088451366446846 0.0271854143285845 1.0 0.5779130836679023 7 Q9H0H5,Q8TB61,Q70HW3,Q9HC21,Q9UBX3 5 +Regulation of pattern recognition receptor signaling pathway 0.6076662251657532 2.205830405146579 0.0273958765457702 1.0 0.5779130836679023 18 Q06481,O75955,Q07021,O43657,Q9NUD5,Q9NQC3 6 +Negative regulation of leukocyte mediated immunity 0.8863414374608031 2.204475834453564 0.0274908976154559 1.0 0.5779130836679023 5 P15529,P04439,P09601 3 +Endoplasmic reticulum membrane organization 0.8016462640419696 2.1984301019495893 0.0279184705369843 1.0 0.5779130836679023 7 Q9P2W9,Q15363,Q9NQC3 3 +Glycolipid biosynthetic process 0.7164699873588686 2.193422091693872 0.0282769820918808 1.0 0.5779130836679023 10 Q99805,Q8NBX0,Q16739,Q92643,Q9H490 5 +Atp transport 0.8224483098129374 2.186162423938941 0.0288037242989187 1.0 0.5779130836679023 6 P12235,P12236,P05141,Q08722,Q6NUK1 5 +T cell proliferation 0.5861956794635012 2.1816909049865942 0.0291323526203781 1.0 0.5779130836679023 25 P10644,P02786,P04439,Q92542,P30825,P15529,Q5ZPR3 7 +Peptide catabolic process 0.7136707426113885 2.179028738633946 0.0293295333600149 1.0 0.5779130836679023 10 Q9UIQ6,P55786,P42892,O14773 4 +Forebrain cell migration 0.6780192383525283 2.178420071275437 0.0293747769317052 1.0 0.5779130836679023 13 Q96N66,P00533,O94813,P07942,Q9NQC3 5 +Cation transport 0.4702074452471756 2.171921021959673 0.0298616205439745 1.0 0.5779130836679023 152 Q9HC07,O75844,Q96QD8,P55011,O75964,P62942,Q70HW3,P05556,Q8N4V1,P05141,P05023,Q7KZN9,Q9Y6M7,O15173,P21796,Q8IUH4,Q15526,Q15043,P05067,Q96PU5,Q8NEW0,O43808,P17612,P02786,Q9HC21,Q8IYU8,Q9Y619,Q9UDW1,Q9HD20,P0DP25,Q9BPX6,P20020,P03915,P06756,P98164,Q13423,P08195,P16615,Q04656,P30825,P00403,P04899,P56134,Q92581,P61421,P54709,P51809,P12235,Q15758,P51790,O76024,Q4KMQ2,O95202,O00400,P13073,P36543 56 +Microglial cell activation 0.939324368645453 2.17170704799161 0.0298777665855549 1.0 0.5779130836679023 4 P53634,P05067,P15260 3 +Astrocyte activation 0.9393243686454532 2.17170704799161 0.0298777665855549 1.0 0.5779130836679023 4 Q07954,P05067,P15260 3 +Regulation of lipid transport 0.5851689041627194 2.170782398239632 0.0299476251000512 1.0 0.5779130836679023 19 P06756,O15260,Q9NV96,Q07954,Q9H2C2,Q9Y6B6,P31751 7 +Positive regulation of t cell proliferation 0.70051495875202 2.168037764101319 0.0301558133717418 1.0 0.5779130836679023 11 P04439,P02786,Q5ZPR3,P30825 4 +Regulation of lymphocyte mediated immunity 0.5848595552267765 2.1673252149940785 0.0302100651644807 1.0 0.5779130836679023 21 P02786,Q9NUQ9,P04439,O15400,P15529,P11279 6 +Cell morphogenesis involved in neuron differentiation 0.4170915524650311 2.1629313036311015 0.0305464636764698 1.0 0.5779130836679023 87 Q15375,O15031,P35613,P42892,P98155,Q06481,O75955,O94813,Q92581,O14786,O00264,Q9NQC3,P05067,Q13641,Q96PU5 15 +Calcium mediated signaling 0.6614837523821494 2.160306678971337 0.0307489362722197 1.0 0.5779130836679023 14 O75844,P17612,P16615,P42345,P00533,P0DP25 6 +Regulation of phagocytosis 0.6324264706587561 2.159145010176021 0.0308389186508779 1.0 0.5779130836679023 16 P06756,Q06481,Q08722,Q4KMQ2,Q08431 5 +Mitochondrion organization 0.4854482378855073 2.157523705758798 0.0309648820961161 1.0 0.5779130836679023 176 Q9NS69,P52789,Q13501,Q8N4H5,Q9Y4P8,O96008,P45880,P14406,O60830,Q96A26,Q9UDX5,P39210,Q9BUR5,Q9Y6M9,Q15070,Q9Y512,Q96CU9,Q5T9A4,P05141,Q9Y6C9,Q9P0J0,Q13505,P21796,Q15526,Q99595,Q16891,P04062,Q9NVI7,P02786,Q9UG56,O14925,O95831,P0DP25,Q9NVH1,P03886,O75438,P03915,Q9NUQ9,Q04656,O96000,Q86Y39,Q8IWA4,O43676,Q92692,Q9Y2R0,P27544,Q6DKK2,O95169,Q9BSK2,Q9H3K2,P12235,P55786,Q3ZCQ8,Q9BWH2,Q9H061,O60313,O95202,Q5XKP0,P11233 59 +Protein exit from endoplasmic reticulum 0.5832254322307613 2.1562881121178843 0.0310611749533618 1.0 0.5779130836679023 22 Q92544,Q9UBV2,O15260,P51572,Q9NV96,Q8TCT9,Q92673,Q9HCU5,Q9Y6B6,Q9BUN8,Q9NR31 11 +Aminoglycan biosynthetic process 0.8156589361592466 2.1557432695640033 0.0311037174596413 1.0 0.5779130836679023 6 Q7LGA3,P06865 2 +Regulation of cholesterol metabolic process 0.7920948360085632 2.154401286112179 0.0312087158107117 1.0 0.5779130836679023 7 P04114,P01130,Q9H2C2 3 +Ceramide biosynthetic process 0.6975887134800459 2.1525556944366393 0.0313536137396206 1.0 0.5779130836679023 11 P04062,Q96G23,Q16739,P27544,Q13510 5 +Response to manganese ion 0.8739518908053451 2.1524078464764087 0.0313652462548574 1.0 0.5779130836679023 5 P05067,P02786 2 +Regulation of steroid metabolic process 0.6460778014757674 2.152279916648593 0.0313753146210746 1.0 0.5779130836679023 15 Q6IAA8,P04114,P16435,Q9H2C2,P01130,Q13510 6 +Protein targeting to vacuole 0.6731667384045258 2.151323750769091 0.0314506548794708 1.0 0.5779130836679023 13 Q9H9H4,Q99523,Q14108,Q92673,P20645 5 +Membrane docking 0.5812292078474852 2.149523308384667 0.0315929404561496 1.0 0.5779130836679023 26 Q13190,O60499,Q7Z6M1,O15400,P16615,Q86Y82,Q13277,Q9UNK0 8 +Low density lipoprotein particle clearance 0.6848917634121992 2.1472240280778383 0.0317754506772487 1.0 0.5779130836679023 12 Q8WTV0,P09601,P38571,P04114,Q9H4M9,Q9Y2B0,P01130 7 +Oligosaccharide catabolic process 0.9330928173171502 2.147017635128886 0.0317918776816745 1.0 0.5779130836679023 4 P17900,O00462,Q99519 3 +Ganglioside catabolic process 0.9330928173171495 2.1470176351288828 0.0317918776816747 1.0 0.5779130836679023 4 P17900,P06865,Q99519 3 +Ganglioside metabolic process 0.9330928173171495 2.1470176351288828 0.0317918776816747 1.0 0.5779130836679023 4 P17900,P06865,Q99519 3 +Inflammatory response 0.4879496872636136 2.145607090224663 0.0319043392932392 1.0 0.5779130836679023 67 P09601,P05556,Q08722,Q8IV08,Q96J02,P05067,P04062,P02786,Q53EL6,P53634,P60900,P42785,Q99735,P01130,Q9BXW9,P38571,Q06481,Q9Y624,P51809,P48960,Q4KMQ2,Q9BQE5 22 +Connective tissue development 0.5805988340999946 2.145056098712471 0.0319483619431635 1.0 0.5779130836679023 26 O75844,Q04656,Q92896,Q9NX62,P16435,O15173,Q92673,Q96HY6,P43490 9 +Regulation of protein exit from endoplasmic reticulum 0.7879601767558808 2.1352720644985586 0.0327387934076561 1.0 0.5779130836679023 7 Q9Y6B6,Q9NV96,Q9NR31,Q92673 4 +Heparan sulfate proteoglycan metabolic process 0.8691718988252508 2.1322406701180108 0.032987066637877 1.0 0.5779130836679023 5 Q7LGA3,Q99805 2 +Cerebellar purkinje cell layer development 0.8101931133427716 2.1311772695622806 0.033074540879797 1.0 0.5779130836679023 6 P54802,O14949,Q04656 3 +Protein maturation 0.482086957590408 2.1276469258822264 0.0333663684301424 1.0 0.5779130836679023 68 O75844,Q9H9S5,Q9NRN7,Q9UG56,Q9BXS4,Q92673,O75787,P16870,Q99538,Q92542,Q10471,Q15005,P67812,Q86UY6,O75976,P42892,O75503,Q92896,Q8TCT9 19 +Sterol metabolic process 0.5661471296104634 2.124106024070927 0.033661278899074 1.0 0.5779130836679023 38 Q15392,P61916,P04114,P05067,Q14534,P04062,O15118,P98155,Q16850,P35610,Q14849,P01130,P38571,P00387,Q15800,Q9H2C2,Q14739,Q8WTV0,P14324,Q06520,P16435,Q9BQE5 22 +Establishment of protein localization to vacuole 0.6549067360831875 2.12238786218841 0.0338051806258323 1.0 0.5779130836679023 14 Q9H9H4,Q99523,Q14108,Q92673,P20645 5 +Regulation of lipoprotein metabolic process 0.8657628132301081 2.117830699185349 0.0341894084047322 1.0 0.5779130836679023 5 Q5HYI8,P04062,P06756 3 +Regulation of defense response 0.4201792175585693 2.113931444751056 0.0345211230634985 1.0 0.5779130836679023 81 O75844,Q08722,Q9NUD5,Q96J02,P05067,P04062,P53634,Q07021,P60900,Q9NZ08,O43657,Q99735,Q8IZ81,P01130,Q9BXW9,P01889,Q06481,P51809,P04439,P11279 20 +Positive regulation of leukocyte proliferation 0.5936440837435404 2.113766709891207 0.034535197596045 1.0 0.5779130836679023 18 P04439,P02786,Q5ZPR3,P30825 4 +L alpha amino acid transmembrane transport 0.7007966896899205 2.1125087032874483 0.0346428402605079 1.0 0.5779130836679023 10 P08195,P05556,O75915,P30825,Q9Y619,O60831 6 +Vesicle mediated transport in synapse 0.5728352739692387 2.112427844096898 0.0346497688537572 1.0 0.5779130836679023 31 P20339,P19022,Q15042,P27824,P16615,P14672,P51790,Q7L0J3,Q5SQN1,P0DP25,Q13277,Q96CW1,Q4J6C6 13 +Neuromuscular process controlling balance 0.6784919789403668 2.11232551633418 0.0346585387243514 1.0 0.5779130836679023 12 P17900,O14773,P05067,P10253 4 +Animal organ morphogenesis 0.4215083747893905 2.10765971863363 0.0350604339617874 1.0 0.5779130836679023 97 O75844,O75569,P62942,O95470,P04920,P53701,O14786,P54802,P04062,Q9P273,P19022,Q53EL6,P42345,Q8TAA9,Q9UID3,P07942,Q9NQC3,P19021,Q9BXW9,P98164,P16870,P00533,O94813,P10253,P35613,O75386,Q92896,Q15555,Q9NX62,Q15363,P16435,Q8NBN7 32 +Positive regulation of endocytosis 0.5758566044841013 2.1051685014041626 0.035276643074088 1.0 0.5779130836679023 21 Q06481,Q07954,Q4KMQ2,P50897,Q96PU5 5 +Negative regulation of amyloid precursor protein catabolic process 0.7538526695128016 2.1047032117083972 0.0353171507470266 1.0 0.5779130836679023 8 O95197,Q92673 2 +Appendage development 0.6517381414646698 2.1040599886072595 0.0353732144938854 1.0 0.5779130836679023 14 P19021,Q5SZK8,P42892 3 +T cell mediated cytotoxicity 0.7812031500189905 2.1039195096082683 0.0353854688346484 1.0 0.5779130836679023 7 P01889,Q9NUQ9,P04439,O15400,P53634 5 +Neuromuscular process 0.575292483005357 2.1029602349911825 0.0354692456683765 1.0 0.5779130836679023 24 O75844,P07686,O14773,P05067,P17900,P10253 6 +Mitophagy 0.6513116999278983 2.1015903830661244 0.0355891730140052 1.0 0.5779130836679023 14 P12235,P27544,Q13501,P21796 4 +Mitochondrial transmembrane transport 0.5462122756504932 2.1003529709079625 0.0356978027714993 1.0 0.5779130836679023 47 P12235,O75964,P12236,O60830,P05141,Q3ZCQ8,O14925,O95202,O95831,Q8IYU8,Q9Y619,P21796,Q9BPX6,P23786,Q9H2D1,Q6P4A7,Q99595,Q9BSK2 18 +Regulation of neuron projection development 0.475055496558508 2.0980123380549096 0.0359040554761023 1.0 0.5779130836679023 69 Q86VR2,Q12834,O14786,Q96PU5,Q15375,Q9P273,P19022,P98155,P08069,Q9NQX7,Q9NQC3,Q9UQB8,Q96G23,O94813,Q14108,O15031,P10586,Q9NV96,Q13308,P07196,Q9H4M9 21 +Proteoglycan biosynthetic process 0.8607520747741888 2.0966103046405227 0.0360280863400055 1.0 0.5779130836679023 5 Q7LGA3,Q99805 2 +Regulation of synapse assembly 0.7518573652097341 2.095085359001202 0.0361634052042896 1.0 0.5779130836679023 8 Q15375,P05067 2 +Calcium ion import 0.6973477887710509 2.094597958579957 0.036206746847017 1.0 0.5779130836679023 10 P16615,O75844,Q8IYU8,P21796 4 +Glomerulus development 0.7782428176885297 2.090148118525241 0.0366044963429399 1.0 0.5779130836679023 7 O00592,P14543 2 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.9187884671266696 2.090108384027854 0.036608064718105 1.0 0.5779130836679023 4 P04439,Q9UIQ6 2 +Heparan sulfate proteoglycan biosynthetic process 0.9178412883458356 2.0863285667726976 0.0369488707144376 1.0 0.5779130836679023 4 Q7LGA3 1 +Embryonic digit morphogenesis 0.7497608251502417 2.0849679988272 0.0370722054423748 1.0 0.5779130836679023 8 Q5SZK8,P42892 2 +Negative regulation of wnt signaling pathway 0.589260783906217 2.0847895501858513 0.0370884076861273 1.0 0.5779130836679023 18 P19022,P48729,Q07954,P49815,P50402,Q13641 6 +T cell mediated immunity 0.6842107358160676 2.081410727625988 0.0373963275953521 1.0 0.5779130836679023 11 P01889,Q9NUQ9,P04439,O15400,P53634,P15529 6 +Positive regulation of mononuclear cell migration 0.7217101175816006 2.0807661991087314 0.0374553114158431 1.0 0.5779130836679023 9 Q99538,P05067,Q08722,Q4KMQ2 4 +Neuron recognition 0.776125537140237 2.080285337863128 0.0374993688322049 1.0 0.5779130836679023 7 P35613,Q9NQC3,P05067 3 +Regulation of membrane lipid distribution 0.7981826118931209 2.076955819123634 0.0378056371203197 1.0 0.5779130836679023 6 Q9NV96,Q9H2C2 2 +Collateral sprouting 0.914810563906816 2.074224592404585 0.0380584572938174 1.0 0.5779130836679023 4 P05067 1 +Regulation of endocytosis 0.5378451310557221 2.069608201454926 0.0384890494171243 1.0 0.5779130836679023 49 P06756,Q9H223,P61020,Q06481,O75955,O00560,Q07954,Q4KMQ2,P50897,P0DP25,P57105,P51148,P05067,Q96PU5 14 +Memory 0.6915016201529915 2.064150522751704 0.0390034469577498 1.0 0.5779130836679023 10 P98155,Q99538,P01130,P14672 4 +Regulation of amyloid fibril formation 0.8528658185298877 2.0631151985474268 0.0391016844953178 1.0 0.5779130836679023 5 P05067 1 +Maintenance of location 0.4713747025831682 2.059858866129044 0.0394120350583093 1.0 0.5779130836679023 69 O43731,P52789,O94901,P62942,P04114,Q14534,Q8NEW0,P04062,P24390,P17612,Q92673,P0DP25,O15258,P06756,P07686,P17900,P10253,Q8WTV0,O43292,Q9H4M9,O95202 21 +Amino acid transmembrane transport 0.6439648508967832 2.058932688265819 0.039500687145175 1.0 0.5779130836679023 14 Q96QD8,Q15758,P08195,P05556,O75915,P30825,Q9Y619,O60831 8 +Regulation of nitric oxide metabolic process 0.6904866553986052 2.0588533004460885 0.0395082938754636 1.0 0.5779130836679023 10 P06280 1 +Positive regulation of leukocyte migration 0.6160409335457562 2.058180762449037 0.0395727845824094 1.0 0.5779130836679023 16 Q99538,P05067,Q08722,Q4KMQ2 4 +Nadh dehydrogenase complex assembly 0.5680057100101167 2.055351195985858 0.0398450957372304 1.0 0.5779130836679023 26 O96000,Q9Y6M9,Q15070,Q9P0J0,Q86Y39,Q9H061,O43676,P03886,O75438,O95169,P03915 11 +T cell activation 0.5108406617841403 2.0532325169957404 0.0400500321581913 1.0 0.5779130836679023 58 P10644,P24390,P02786,Q9NUQ9,P04439,Q04656,Q08722,Q92542,P30825,Q5HYI8,P15529,Q96J02,O96005,Q5ZPR3 14 +Adult locomotory behavior 0.615117258427774 2.05245462246182 0.0401255007314962 1.0 0.5779130836679023 16 O75844,P50897,O15118,P05067 4 +Mammary gland development 0.5682935074537212 2.052287803365141 0.0401417006275395 1.0 0.5779130836679023 22 P52789,Q9UNS2,Q04656,Q13505,Q9NQC3,P19021,P31751 7 +Regulation of monocyte chemotaxis 0.8499101321013194 2.0505311521720446 0.0403126270492428 1.0 0.5779130836679023 5 Q99538,O94813 2 +Import into cell 0.5672875447701109 2.0502089196463085 0.040344047954179 1.0 0.5779130836679023 26 P54709,P98164,P55011,P08195,P05023,P05556,O75955,P30825,P11166,Q92581,Q15043,P31751 12 +Sodium ion homeostasis 0.792068908121265 2.0492287974666517 0.0404397473813671 1.0 0.5779130836679023 6 P54709,P05023,P55011,Q96PU5 4 +Negative chemotaxis 0.90851706450437 2.049043587150719 0.0404578529781836 1.0 0.5779130836679023 4 Q15375,P06756 2 +Protein localization to endoplasmic reticulum 0.5588020367315847 2.046904453001936 0.0406674667982456 1.0 0.5779130836679023 36 O43731,Q9Y5M8,O15258,P24390,Q15042,O43292,Q15005,Q15629,P33908,Q9NQC3,Q96HY6 11 +Cellular hormone metabolic process 0.6137829995271139 2.0441766230868006 0.0409361017113489 1.0 0.5779130836679023 16 Q6NUM9,P42892,O95470,Q9HB40,Q14849,Q8NBN7,Q53GQ0 7 +Eye photoreceptor cell differentiation 0.8483761993883452 2.0439938050957855 0.0409541591469362 1.0 0.5779130836679023 5 P54802,Q15555 2 +Vitamin d metabolic process 0.9061987536897322 2.039752077800832 0.0413750250718856 1.0 0.5779130836679023 4 Q99538,P98164,P38435 3 +Protein import into mitochondrial matrix 0.7132394739173186 2.0382000528052795 0.0415299302340739 1.0 0.5779130836679023 9 Q3ZCQ8,O60830,O14925,Q99595 4 +Regulation of t cell mediated cytotoxicity 0.8461286089238746 2.034406946250422 0.0419105820911185 1.0 0.5779130836679023 5 Q9NUQ9,P04439,O15400,P01889 4 +Positive regulation of t cell mediated cytotoxicity 0.8461286089238746 2.034406946250422 0.0419105820911185 1.0 0.5779130836679023 5 Q9NUQ9,P04439,O15400,P01889 4 +Regulation of mononuclear cell migration 0.5815987743935791 2.033910616523847 0.0419606083568835 1.0 0.5779130836679023 18 Q99538,Q08722,O94813,Q4KMQ2,P05067 5 +Smooth muscle cell migration 0.6510573606977396 2.026768376577392 0.0426861059626293 1.0 0.5779130836679023 13 Q04656,Q07954,O15511,O94813,Q13685,Q92673,O14786 7 +Autophagosome organization 0.5644154027972562 2.025241311940404 0.0428425915274655 1.0 0.5779130836679023 23 P20339,P04062,Q15286,Q9Y4P8,Q15042,P16615,Q9Y4P1,Q9H0U4,P62820,Q86Y82,P11234,P51149 12 +Glial cell migration 0.6622574819375937 2.0231530965833286 0.0430573657037574 1.0 0.5779130836679023 12 Q96N66,Q96G23,P07686,P07942,Q9NQC3 5 +Protein insertion into membrane 0.563514376582403 2.023144862442797 0.043058214387847 1.0 0.5779130836679023 26 Q9NS69,Q8N4V1,P00533,Q15070,Q9P0J0,Q9Y512,Q15629,Q96A33 8 +Regulation of axonogenesis 0.5637159330834207 2.0202994382981236 0.0433523370451143 1.0 0.5779130836679023 23 Q15375,O15031,P19022,Q9NQC3,O94813,O14786 6 +Synaptic vesicle exocytosis 0.6096511958812956 2.0184932053329225 0.0435399210993596 1.0 0.5779130836679023 16 P20339,Q15042,P16615,Q7L0J3,Q5SQN1,P0DP25,Q13277,Q4J6C6 8 +Protein targeting to lysosome 0.6716972073151309 2.014319990453593 0.0439759484883481 1.0 0.5779130836679023 11 Q14108,P20645,Q99523,Q92673 4 +Respiratory chain complex iv assembly 0.7346690282416857 2.0117908199540144 0.0442419920579539 1.0 0.5779130836679023 8 Q15070,Q9Y2R0,Q7KZN9 3 +Negative regulation of receptor mediated endocytosis 0.681311883844646 2.0108189840533885 0.0443445801666608 1.0 0.5779130836679023 10 O00560,P05067 2 +Endosome organization 0.5592082577089934 1.9980058453174545 0.0457160264086939 1.0 0.5779130836679023 28 Q9P0T7,Q9H9H4,Q6IAA8,Q13501,P61020,Q8WUM4,P51790,Q9BTU6,Q14108,P51149 10 +Positive regulation of cell cell adhesion 0.5556155261851644 1.9979466533992856 0.0457224439759669 1.0 0.5779130836679023 33 Q9Y624,P02786,Q9NUQ9,P04439,O75955,Q08722,P30825,P15529,O00592,Q5ZPR3 10 +Receptor recycling 0.7312096439123974 1.9949310109193472 0.0460504047318126 1.0 0.5779130836679023 8 P01130,P42892,Q92673 3 +Macrophage activation 0.7575626010480475 1.993343192573766 0.0462238797866805 1.0 0.5779130836679023 7 P53634,P05067,P15260 3 +Endomembrane system organization 0.4626704837157535 1.99159439602283 0.0464155787462903 1.0 0.5779130836679023 162 O43633,O14657,O94901,O75844,Q13501,Q6IAA8,Q9P2W9,Q8N4V1,Q5SQN1,P62820,Q9BTU6,Q13277,Q9NP72,Q96A33,P40616,P61020,Q9H4A5,O95197,Q6DD88,Q14789,Q7Z3D4,Q9UID3,Q9NQC3,Q9P0T7,Q8TBA6,Q9H9H4,Q9UQB8,Q15042,P57088,P16615,Q9Y3B3,Q7RTS9,P61019,Q14108,Q9H2C2,Q5VU43,Q15629,Q92692,P50402,P49755,Q13190,O15260,Q8WUM4,O43760,O75955,O00429,P51790,Q12907,Q86XL3,Q15363,Q4KMQ2,Q16739,P51149,Q8NHH9,P31751,Q8NFQ8 56 +Regulation of metallopeptidase activity 0.8350315462738415 1.9869343385763656 0.0469296737169575 1.0 0.5779130836679023 5 Q07954,Q92673 2 +Cytokine production involved in inflammatory response 0.7560686632530687 1.9863094248587263 0.0469989767750314 1.0 0.5779130836679023 7 Q8IV08 1 +Regulation of mitochondrion organization 0.5417177332900779 1.9828216963311331 0.0473873496344927 1.0 0.5779130836679023 42 Q9H3K2,Q13501,P02786,P12235,Q9NUQ9,Q96A26,P05141,Q9UG56,O60313,P21796,P27544,P11233 12 +Xenobiotic transport 0.8919550638514253 1.9824815321611524 0.0474253723327404 1.0 0.5779130836679023 4 Q9NV96 1 +Intestinal absorption 0.7021922499605623 1.9823704092283736 0.0474377989332237 1.0 0.5779130836679023 9 Q9Y624,P01130,Q16739 3 +Endoplasmic reticulum tubular network organization 0.6754784752065709 1.9801378706541508 0.0476880387843556 1.0 0.5779130836679023 10 Q15042,Q6DD88,O95197,Q9NQC3,Q8NHH9 5 +Regulation of leukocyte degranulation 0.8332618078301598 1.9793421930112152 0.0477774921611771 1.0 0.5779130836679023 5 P11279,P09601 2 +Mitochondrial calcium ion homeostasis 0.7007282114069179 1.9749447871363248 0.0482744140623425 1.0 0.5779130836679023 9 Q16891,O95202,Q8IYU8,Q9BPX6 4 +Regulation of leukocyte mediated immunity 0.5546791558141388 1.968712794016767 0.0489860812825597 1.0 0.5779130836679023 29 P01889,P02786,P09601,Q9NUQ9,P04439,O15400,P15529,P11279 8 +Positive regulation of protein localization to membrane 0.5556126347676646 1.9686511912475089 0.0489931597758912 1.0 0.5779130836679023 27 O15258,Q13501,P00533,Q07954,O00264,Q13277,P31751 7 +Amino acid import 0.7518025310724559 1.966193636164003 0.0492762473103953 1.0 0.5779130836679023 7 Q15758,P08195,P05556,O75915,P30825 5 +Lipid storage 0.5553320790092229 1.9653198396767244 0.0493772307418713 1.0 0.5779130836679023 19 P04062,P06756,Q8WTV0,P07686,P04114,P17900,Q14534 7 +Regulation of toll like receptor signaling pathway 0.698104765740789 1.9616229977872863 0.0498063927366734 1.0 0.5779130836679023 9 Q06481,O75955,Q9NQC3 3 +Regulation of amino acid transport 0.8287401574803159 1.95991795387343 0.050005380773765 1.0 0.5779130836679023 5 Q7L0J3,P05556,P55011,Q15042 4 +Amine transport 0.8287401574803159 1.95991795387343 0.050005380773765 1.0 0.5779130836679023 5 Q7L0J3,P05556,P55011,Q15042 4 +Endoplasmic reticulum organization 0.5404518563346863 1.9594031940640104 0.0500655869112396 1.0 0.5779130836679023 41 O14657,Q00765,Q9P2W9,Q8N4V1,P50542,Q9NP72,Q96A33,Q6DD88,O95197,P49257,Q9NQC3,Q15042,P57088,Q15629,O00429,Q12907,Q15363,Q8NHH9,Q8NFQ8 19 +Exocytic process 0.5855533151037764 1.958502821053244 0.050171040341292 1.0 0.5779130836679023 17 P51809,O00186,Q7Z6M1,Q7L0J3,Q5SQN1,P54920,Q13277 7 +Positive regulation of pattern recognition receptor signaling pathway 0.6973287120775062 1.9576783727577012 0.050267764554355 1.0 0.5779130836679023 9 Q9NUD5,Q9NQC3 2 +Response to ischemia 0.671073908546427 1.9568996177706837 0.0503592715191494 1.0 0.5779130836679023 10 P52789,Q13501 2 +Negative regulation of nervous system development 0.5540266643328644 1.9562236258657035 0.0504388165360965 1.0 0.5779130836679023 19 Q15375,Q06481,Q96G23,Q92673,Q9NQC3 5 +Phagocytosis 0.5343551243389528 1.952129751307441 0.0509228018078806 1.0 0.5779130836679023 44 Q92544,P20339,Q8IX05,P06756,P51809,Q96JJ3,Q8WTV0,Q06481,Q08722,P51790,Q07954,Q14964,Q4KMQ2,Q08431,Q5KU26,P51149,P01130 17 +Bone morphogenesis 0.7482390375402291 1.949357010715063 0.0512528046181337 1.0 0.5779130836679023 7 O75844,Q92896,Q9NX62 3 +Neuron projection arborization 0.748087256686912 1.948639199184599 0.0513385274274371 1.0 0.5779130836679023 7 Q9HCE1,P98164,Q13641 3 +Regulation of monooxygenase activity 0.6592765496279533 1.947208868980059 0.0515096988410399 1.0 0.5779130836679023 11 Q8WTV0,Q04656,P06280,Q8TCT9,P00533,P16435,P0DP25 7 +Amyloid precursor protein biosynthetic process 0.8256317270247981 1.9465427071086956 0.0515895830919248 1.0 0.5779130836679023 5 Q9NQX7,Q9Y287 2 +Positive regulation of amyloid precursor protein catabolic process 0.7212714030195718 1.946318040730069 0.0516165478186181 1.0 0.5779130836679023 8 P15260 1 +Negative regulation of lymphocyte mediated immunity 0.8827748723321472 1.9454048662644092 0.0517262695338702 1.0 0.5779130836679023 4 P15529,P04439 2 +T cell differentiation in thymus 0.7470419172738441 1.943693997331549 0.0519323629224157 1.0 0.5779130836679023 7 Q5HYI8,O96005 2 +Calcium import into the mitochondrion 0.8248182345162574 1.943039392006072 0.0520113989773132 1.0 0.5779130836679023 5 Q8IYU8,P21796 2 +Synaptic vesicle localization 0.6464957359588919 1.9356939943320048 0.0529051904524775 1.0 0.5779130836679023 12 Q92572,Q96A57,P14672 3 +Positive regulation of protein kinase b signaling 0.5515303981446257 1.935056464078721 0.0529833671632495 1.0 0.5779130836679023 21 Q86UE4,P98164,P05556,Q07021,P00533,Q9NQC3,Q13641,Q9Y251 8 +Intracellular protein transmembrane transport 0.5512400403259687 1.9330069878257716 0.0532353369840492 1.0 0.5779130836679023 21 O96008,O60830,Q3ZCQ8,O14925,O95831,P31751,Q99442,Q15629,Q99595 9 +Appendage morphogenesis 0.6566340426813365 1.9328644884869923 0.0532528935099203 1.0 0.5779130836679023 11 Q5SZK8,P42892 2 +Regulation of leukocyte proliferation 0.5505981195776642 1.9299020667948097 0.053618973299957 1.0 0.5779130836679023 26 P10644,P02786,P04439,P30825,P15529,Q5ZPR3 6 +Regulation of biomineralization 0.6916481703971413 1.9287512312503847 0.0537617528248008 1.0 0.5779130836679023 9 Q14596,O75844,P04920,Q4KMQ2 4 +Positive regulation of glycoprotein metabolic process 0.7655392615119789 1.9279284014102116 0.0538640324948194 1.0 0.5779130836679023 6 P62820,Q9H0U4,Q92542 3 +Positive regulation of phagocytosis 0.7174084248469015 1.9273514310886992 0.0539358480925462 1.0 0.5779130836679023 8 Q06481,Q08722,Q4KMQ2 3 +Protein localization to cell surface 0.5654879163579452 1.9259882882962325 0.0541058362330344 1.0 0.5779130836679023 18 Q92544,Q9H490,Q96PU5,Q13277 4 +Negative regulation of growth 0.5474584323541009 1.9245084566341537 0.054290881756007 1.0 0.5779130836679023 31 Q15375,Q99538,P36896,Q9NQC3,Q9P0J0,O94813,P50897,O14786 8 +Positive regulation of lymphocyte mediated immunity 0.5802261273712108 1.9239127728473715 0.0543655179384934 1.0 0.5779130836679023 17 P02786,Q9NUQ9,P04439,O15400,P11279 5 +Cholesterol efflux 0.6647909592449834 1.9236438346463165 0.0543992425806654 1.0 0.5779130836679023 10 O15118,P61916,Q8WTV0,Q07954,P04114,Q86Y82 6 +Forebrain generation of neurons 0.7641955069341846 1.9217422723092836 0.0546381953404588 1.0 0.5779130836679023 6 O14949,Q04656 2 +Embryonic appendage morphogenesis 0.6642706257433068 1.920884053097249 0.0547463266323113 1.0 0.5779130836679023 10 Q5SZK8,P42892 2 +Interferon gamma production 0.7158438536956919 1.9196583957670676 0.0549010626576933 1.0 0.5779130836679023 8 Q9NUQ9,P04439,Q08722,Q5ZPR3 4 +Cell recognition 0.5492984258897249 1.917848465416516 0.0551302283508536 1.0 0.5779130836679023 23 P35613,Q8WTV0,P45880,Q08431,Q5KU26,Q9NQC3,P05067 7 +Protein lipid complex subunit organization 0.763349734153004 1.9178465950646744 0.0551304655786666 1.0 0.5779130836679023 6 P04114,P17612,Q8WTV0 3 +Purine containing compound transmembrane transport 0.7150305889134697 1.9156569974570563 0.0554087694342224 1.0 0.5779130836679023 8 P05141,P12235,P12236,Q8TB61 4 +Establishment of protein localization to mitochondrial membrane 0.6064580265947365 1.913843681945524 0.055640132179306 1.0 0.5779130836679023 15 Q9NS69,Q15070,Q9P0J0,Q9Y512,P0DP25 5 +Regulation of response to external stimulus 0.4268333447138147 1.9132998953255504 0.0557096711352163 1.0 0.5779130836679023 122 O75844,P55011,P80303,Q08722,Q9NUD5,Q13277,Q96J02,O14786,P05067,P04062,P53634,Q07021,P60900,Q9NZ08,O43657,Q99735,Q8IZ81,P01130,Q13641,Q9BXW9,P01889,Q9NUQ9,Q99538,Q06481,Q96G23,O94813,Q9Y251,P51809,P10586,P04439,Q4KMQ2,P11279 32 +Regulation of natural killer cell mediated immunity 0.8177861381906899 1.9127049543462984 0.0557858345901767 1.0 0.5779130836679023 5 P11279,P01889,P04439 3 +Positive regulation of macroautophagy 0.5485151426678156 1.912688382713767 0.0557879573068635 1.0 0.5779130836679023 22 P12235,Q15042,P09601,Q13137,O15269,P21796,P27544 7 +Telencephalon glial cell migration 0.7141277333365956 1.9112127522294329 0.0559772457539149 1.0 0.5779130836679023 8 P07942,Q96N66,Q9NQC3 3 +Cerebral cortex radially oriented cell migration 0.7141277333365956 1.9112127522294329 0.0559772457539149 1.0 0.5779130836679023 8 P07942,Q96N66,Q9NQC3 3 +Positive regulation of chemotaxis 0.5632006456113706 1.9105636449533427 0.0560606800824352 1.0 0.5779130836679023 18 Q99538,O94813,Q4KMQ2,Q13277,O14786,Q13641 6 +Regulation of jnk cascade 0.6185360376649042 1.9096742305170031 0.0561751709277253 1.0 0.5779130836679023 14 Q53EL6,O00560,P00533,P08069,Q96J02,P05067 6 +Cell maturation 0.5475356863528295 1.9085371402087004 0.0563218276228749 1.0 0.5779130836679023 20 P04062,Q9Y2W6,O75503,P09622,P05067 5 +Pathway restricted smad protein phosphorylation 0.8162471388474445 1.9060541053767592 0.0566431862899243 1.0 0.5785791915681353 5 Q07954 1 +Signaling receptor ligand precursor processing 0.8722309071740245 1.902663405392175 0.0570844798994554 1.0 0.5793475152452898 4 P42892,P16870 2 +Positive regulation of mitophagy 0.8714332568055021 1.8994232833460525 0.0575088445747598 1.0 0.5793475152452898 4 P27544,P12235,P21796 3 +Regulation of amyloid beta clearance 0.8142410164862166 1.897378104667178 0.0577780532819298 1.0 0.5793475152452898 5 Q07954,P15260 2 +Regulation of production of small rna involved in gene silencing by rna 0.735855021671216 1.890606715305029 0.0586768631629626 1.0 0.5793475152452898 7 O75844 1 +Eye photoreceptor cell development 0.8689826788918971 1.889462964978448 0.0588298207755673 1.0 0.5793475152452898 4 P54802,Q15555 2 +Response to copper ion 0.7349305933274289 1.8862063875597277 0.0592671481036211 1.0 0.5793475152452898 7 P05067,P19021,P02786 3 +Negative regulation of cell growth 0.5432448019983326 1.8809646091933272 0.0599767332526182 1.0 0.5793475152452898 28 Q15375,P36896,Q9NQC3,Q9P0J0,O94813,P50897,O14786 7 +Signal peptide processing 0.8101937509644941 1.879852485883709 0.0601281849861776 1.0 0.5793475152452898 5 O75503,Q15005,P67812 3 +Response to amyloid beta 0.7327033311208646 1.8755961044046137 0.0607107617440867 1.0 0.5793475152452898 7 Q07954,P05067 2 +Cellular response to amyloid beta 0.7327033311208646 1.8755961044046137 0.0607107617440867 1.0 0.5793475152452898 7 Q07954,P05067 2 +Regulation of cell activation 0.4686239014817826 1.8743685187294248 0.06087964946565 1.0 0.5793475152452898 65 P09601,Q08722,Q96J02,Q5ZPR3,P02786,P53634,Q14254,P01130,P10644,Q9BXW9,Q9NUQ9,P30825,Q9NPF0,Q92692,O96005,Q9Y624,P51809,P04439,P15529,P11279 20 +Positive regulation of long term synaptic potentiation 0.8644398434575552 1.8709754319659324 0.0613484864009636 1.0 0.5793475152452898 4 Q13501,P05067 2 +Regulation of mitophagy 0.7317325018551106 1.8709675374495327 0.0613495806954937 1.0 0.5793475152452898 7 P27544,P05141,P12235,P21796 4 +Positive regulation of protein localization to cell periphery 0.5414609999857996 1.8682101913723592 0.0617327788027461 1.0 0.5793475152452898 19 O15258,Q13501,P00533,Q07954,O00264,Q13277 6 +Substrate dependent cell migration 0.6443770457451657 1.8660263162295896 0.0620376837320246 1.0 0.5793475152452898 11 O94813,O00560 2 +Negative regulation of cell development 0.5415862303157831 1.862586570189415 0.0625204552687237 1.0 0.5793475152452898 23 Q15375,Q06481,Q96G23,Q92673,Q9NQC3 5 +Chemokine production 0.729871440791587 1.8620883822833985 0.0625906333171997 1.0 0.5793475152452898 7 P05067 1 +Positive regulation of chemokine production 0.729871440791587 1.8620883822833985 0.0625906333171997 1.0 0.5793475152452898 7 P05067 1 +Second messenger mediated signaling 0.5406903943563015 1.8602109861237568 0.0628556813353187 1.0 0.5793475152452898 20 O75844,P17612,P16615,P42345,P00533,P0DP25 6 +Protein localization to mitochondrion 0.4956298336190044 1.858858597116394 0.0630471840446749 1.0 0.5793475152452898 56 P52789,Q9NS69,Q8N4H5,O96008,P51572,O60830,Q9Y6C9,Q15070,Q9P0J0,Q9Y512,Q99595,O14925,O95831,Q15388,P0DP25,Q53H12,P55786,Q3ZCQ8,O00429,P11233 20 +Golgi to vacuole transport 0.7502168988006404 1.857152566820156 0.0632894511988078 1.0 0.5793475152452898 6 P11279,Q99523 2 +Regulation of glucose transmembrane transport 0.632062744395611 1.8548490978929768 0.0636177785517271 1.0 0.5793475152452898 12 Q06481,Q16625,P31751 3 +Digestive system process 0.6418295629822379 1.8520723823134424 0.0640154297099944 1.0 0.5793475152452898 11 Q9Y624,P01130,Q16739 3 +Positive regulation of leukocyte cell cell adhesion 0.5396618331249458 1.8502333758104257 0.0642799204547621 1.0 0.5793475152452898 26 P02786,Q9NUQ9,P04439,Q08722,P30825,Q5ZPR3 6 +Carbohydrate derivative catabolic process 0.52683133828761 1.8500594108925636 0.0643049871847751 1.0 0.5793475152452898 41 P54802,P04062,O00462,P16278,P06865,P04066,P06280,P07686,P08236,Q99519,Q9BTY2,P15586,P17900,Q9Y251 14 +Reactive nitrogen species metabolic process 0.5959498488271382 1.8495328162875064 0.0643809137667368 1.0 0.5793475152452898 15 O43169,Q08722,P06280 3 +Pattern recognition receptor signaling pathway 0.538902865524618 1.8488833173429593 0.0644746631103889 1.0 0.5793475152452898 28 Q96J02,Q06481,Q07021,O75955,O43657,Q5KU26,Q9NUD5,Q9NQC3 8 +Regulation of triglyceride metabolic process 0.8028215223096993 1.8478534480536548 0.0646235464561049 1.0 0.5793475152452898 5 Q92673,P01130,Q96N66,Q8WTV0 4 +Response to mitochondrial depolarisation 0.7258963854281931 1.8430957565497488 0.0653150308026593 1.0 0.5793475152452898 7 P52789,Q13501 2 +Presynapse organization 0.8016704462082977 1.8428484881032028 0.0653511350353026 1.0 0.5793475152452898 5 P05067 1 +Regulation of biological process involved in symbiotic interaction 0.6495078695153044 1.8422262135333485 0.0654420675984417 1.0 0.5793475152452898 10 Q92692,Q9BTY2,P06756,P07237 4 +Positive regulation of pinocytosis 0.8573540137920129 1.84207921158392 0.0654635641211902 1.0 0.5793475152452898 4 P50897 1 +Regulation of pinocytosis 0.8573540137920129 1.84207921158392 0.0654635641211902 1.0 0.5793475152452898 4 P50897 1 +Regulation of nitric oxide synthase activity 0.725617706827395 1.8417628387392992 0.0655098479917322 1.0 0.5793475152452898 7 P0DP25,P06280,Q8WTV0,P00533 4 +Protein o linked glycosylation 0.5946197100260793 1.8413605889488245 0.0655687342145641 1.0 0.5793475152452898 15 Q10472,O43505,Q9H9S5 3 +Positive regulation of toll like receptor signaling pathway 0.8011729311428368 1.8406845319225136 0.0656678019774688 1.0 0.5793475152452898 5 Q9NQC3 1 +Regulation of lipid localization 0.5380446335689208 1.8383968144700833 0.0660039541920081 1.0 0.5793475152452898 26 P06756,O15260,Q8WTV0,Q9NV96,Q07954,P04114,Q9H2C2,Q9Y6B6,Q9H4M9,P31751 10 +Amino acid import across plasma membrane 0.8001968503937 1.8364377702725256 0.0662929377671683 1.0 0.5793475152452898 5 P08195,P05556,O75915,P30825 4 +Toll like receptor 3 signaling pathway 0.8547554502619303 1.8314641749235596 0.0670312902031451 1.0 0.5793475152452898 4 Q5KU26,O75955 2 +Maternal process involved in female pregnancy 0.6380419850606118 1.831286333061376 0.0670578164776014 1.0 0.5793475152452898 11 P07858,P35613,P19021,Q9BQE5 4 +Regulation of protein lipidation 0.8545887783231549 1.830782999066573 0.067132938867841 1.0 0.5793475152452898 4 Q5HYI8,P04062 2 +Leukocyte mediated cytotoxicity 0.6052438653687504 1.8306649929092769 0.0671505612582803 1.0 0.5793475152452898 14 P51809,P01889,Q9NUQ9,P04439,O15400,P53634,P11279 7 +Photoreceptor cell differentiation 0.7445053462931058 1.830638115856417 0.0671545754618325 1.0 0.5793475152452898 6 P54802,Q15555 2 +Regulation of multicellular organism growth 0.6167396500510793 1.829884000285645 0.0672672864105825 1.0 0.5793475152452898 13 Q99538,O75844,P05067 3 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.3873421578871321 1.8291939948021565 0.0673705517479557 1.0 0.5793475152452898 83 O95470,Q15043,O14654,O14786,Q15375,Q92572,P14672,P08069,Q92673,Q9NQC3,Q9UQB8,Q99538,Q99523,P00533,P04899,P11717,Q07954,P51149,P31751,P43490 20 +Transforming growth factor beta production 0.7985051540853982 1.8290735104510831 0.0673885966531486 1.0 0.5793475152452898 5 P15529,P06756 2 +Potassium ion transport 0.5358644398070507 1.8287465278710548 0.0674375887808527 1.0 0.5793475152452898 19 P54709,P55011,P05023,Q4KMQ2,Q92581,Q96PU5 6 +Regulation of hormone metabolic process 0.7439449052531211 1.8280325843632024 0.0675446615138537 1.0 0.5793475152452898 6 O75844,P16435,P05023 3 +Golgi to lysosome transport 0.8534182727848948 1.8259981229309967 0.0678505445853716 1.0 0.5802246990977319 4 Q99523 1 +Regulation of protein localization to plasma membrane 0.5356240088837937 1.8222871520479065 0.0684114266258288 1.0 0.5803838799026694 27 O15258,Q13501,O15400,P00533,Q07954,Q9BXS4,O00264,Q13277,Q9UNK0 9 +Regulation of oxidative phosphorylation 0.6702205074078708 1.8187956154487632 0.0689426175765928 1.0 0.5828490922829734 9 P14406,Q9BSK2 2 +Myeloid leukocyte activation 0.533826291407551 1.8143346361695711 0.0696262222013235 1.0 0.5828490922829734 19 P51809,P09601,P53634,P15260,P01130,P05067 6 +Glycoprotein catabolic process 0.7946903362911758 1.8124484993154664 0.069916924734416 1.0 0.5828490922829734 5 O00462,Q9Y251 2 +Morphogenesis of a branching structure 0.5767064896959563 1.8110778989811631 0.070128794125321 1.0 0.5828490922829734 16 Q15375,O94813,Q9NQC3,Q15363 4 +Cellular response to cadmium ion 0.7191612623075421 1.810830449420996 0.0701671013267959 1.0 0.5828490922829734 7 Q04656,P09601 2 +Pyramidal neuron differentiation 0.8494720727353616 1.809852358615045 0.0703186858309932 1.0 0.5828490922829734 4 O14949,Q04656 2 +Retinal ganglion cell axon guidance 0.7940204406967539 1.8095264661551391 0.070369252276403 1.0 0.5828490922829734 5 Q15375,O94813 2 +Pinocytosis 0.6933789375661175 1.808489747052956 0.0705303111351338 1.0 0.5828490922829734 8 Q06481,Q9H223,P50897 3 +Calcium ion export 0.849051185231997 1.8081290232924965 0.0705864220134069 1.0 0.5828490922829734 4 O95202,P0DP25 2 +Maintenance of location in cell 0.5214275568481669 1.806345537144727 0.0708643830345305 1.0 0.5828490922829734 41 O43731,P52789,O94901,Q8NEW0,P24390,O15258,P62942,O43292,Q92673,P0DP25,O95202,P10253 12 +Regulation of protein localization to cell surface 0.6334046603195388 1.805772939994013 0.0709538139209551 1.0 0.5828490922829734 11 Q13277,Q96PU5 2 +Long chain fatty acid import across plasma membrane 0.8484710181723867 1.8057531091121193 0.0709569128575267 1.0 0.5828490922829734 4 P11166 1 +Regulation of leukocyte chemotaxis 0.5885309127115075 1.8038614355938327 0.0712530318912467 1.0 0.5828490922829734 15 Q99538,Q07021,Q4KMQ2,O94813 4 +Motor neuron axon guidance 0.7914717427041132 1.7984021215405015 0.0721133068192061 1.0 0.5828490922829734 5 O94813 1 +Toll like receptor 4 signaling pathway 0.8466648400548014 1.7983534123509648 0.0721210204967723 1.0 0.5828490922829734 4 Q06481 1 +Regulation of toll like receptor 4 signaling pathway 0.8466648400548014 1.7983534123509648 0.0721210204967723 1.0 0.5828490922829734 4 Q06481 1 +Protein transmembrane import into intracellular organelle 0.611097285491299 1.7971042809441613 0.0723190662346939 1.0 0.5828490922829734 13 O75381,O96008,O60830,Q3ZCQ8,O14925,O95831,Q99595 7 +Negative regulation of leukocyte migration 0.7909084158781123 1.7959418427303282 0.0725037668472277 1.0 0.5828490922829734 5 P09601 1 +Amyloid fibril formation 0.6903059587386287 1.7931811311193893 0.0729439661753725 1.0 0.5828490922829734 8 P01130,P05067 2 +Sodium ion transport 0.5311815674316394 1.7903507662767262 0.0733975398343604 1.0 0.5828490922829734 21 Q96QD8,P55011,P08195,P05023,Q9Y6M7,Q4KMQ2,Q92581,Q96PU5 8 +Sterol transport 0.5313771430903124 1.7886394575462874 0.0736728989813126 1.0 0.5828490922829734 25 O15118,P61916,Q8WTV0,Q07954,P04114,Q14849,Q86Y82,Q9H2C2,P01130 9 +Maintenance of protein location in cell 0.5303896486713522 1.7870310356449963 0.073932472570054 1.0 0.5828490922829734 20 O43731,P52789,O15258,P24390,O43292,Q92673 6 +Reproductive behavior 0.8438833077153851 1.7869489938911156 0.0739457328129544 1.0 0.5828490922829734 4 P05067 1 +Mating 0.8438833077153851 1.7869489938911156 0.0739457328129544 1.0 0.5828490922829734 4 P05067 1 +Mating behavior 0.8438833077153851 1.7869489938911156 0.0739457328129544 1.0 0.5828490922829734 4 P05067 1 +Cellular sodium ion homeostasis 0.8435552640209879 1.7856032980526753 0.074163512531836 1.0 0.5828490922829734 4 P05023,P55011,Q96PU5 3 +Regulation of leukocyte migration 0.5308643636670939 1.784885581774481 0.0742798778078093 1.0 0.5828490922829734 25 P09601,Q99538,Q08722,O94813,P05067 5 +Protein mannosylation 0.8431142835612474 1.7837940827064125 0.0744571314581463 1.0 0.5828490922829734 4 Q9H9S5 1 +Protein o linked mannosylation 0.8431142835612474 1.7837940827064125 0.0744571314581463 1.0 0.5828490922829734 4 Q9H9S5 1 +Lysosomal transport 0.5200118134250623 1.783507267123202 0.074503766080386 1.0 0.5828490922829734 40 P11279,O15118,Q9NZJ7,Q99523,P11717,Q07954,P07602,Q92673,Q14108,P20645,Q9UNK0 11 +Vacuolar transport 0.5138004837240505 1.7826206602401151 0.0746480743619153 1.0 0.5828490922829734 44 P51809,Q92572,Q9H9H4,O15118,P11279,Q9NZJ7,Q96L92,Q99523,P61421,P11717,Q07954,P51149,P07602,Q92673,Q14108,P20645,Q9UID3,Q9UNK0 18 +Taxis 0.4487052329916873 1.781629558317186 0.0748096609521562 1.0 0.5828490922829734 68 Q15375,P06756,O15031,P55011,Q96JJ3,P35613,Q9NUQ9,Q99538,P42892,O94813,Q4KMQ2,P11233,O00264,Q13277,O14786,P05067,Q13641 17 +Forebrain neuron differentiation 0.7875463734728292 1.7812470708631536 0.0748720970300125 1.0 0.5828490922829734 5 O14949,Q04656 2 +Forebrain neuron development 0.7875463734728292 1.7812470708631536 0.0748720970300125 1.0 0.5828490922829734 5 O14949,Q04656 2 +Positive regulation of cell adhesion 0.465610319829903 1.775493495477947 0.0758164386109436 1.0 0.5846597541986862 63 Q9Y624,P06756,P02786,Q9NUQ9,P04439,Q07021,Q08722,O75955,P14543,P30825,P15529,O00592,Q13277,P07237,O14786,Q5ZPR3 16 +Reticulophagy 0.7321058909244168 1.772834092617748 0.0762562023315733 1.0 0.5846597541986862 6 Q9Y6I9,Q96HY6 2 +Positive regulation of autophagy 0.5277957670364349 1.7723178471337235 0.0763418102927511 1.0 0.5846597541986862 30 Q86UE4,P12235,Q15042,P09601,Q9BXS4,Q13137,O15269,P21796,P27544 9 +Viral protein processing 0.6609437980900791 1.7707859761172096 0.0765962988625315 1.0 0.5846597541986862 9 P27824,Q16706,P26572,Q10472,P61009 5 +Positive regulation of jnk cascade 0.7316477535531082 1.7706920463994154 0.0766119258149831 1.0 0.5846597541986862 6 P05067 1 +Proton transmembrane transport 0.5104008978767327 1.76868446375552 0.0769465464166931 1.0 0.5847382521910326 45 P12235,Q13423,O75964,P36543,P05023,P05141,Q04656,P51790,Q7KZN9,P00403,Q9UDW1,P56134,Q15526,Q92581,O00400,P13073,P03915 17 +Cellular response to exogenous dsrna 0.6853190893742889 1.7682867157027549 0.0770129835935631 1.0 0.5847382521910326 8 Q5KU26,Q9NUD5,O75955,P11234 4 +Protein retention in er lumen 0.8386356182354735 1.7654044271126772 0.0774958198835586 1.0 0.5848426564173198 4 O15258,O43731,P24390 3 +Maintenance of protein localization in endoplasmic reticulum 0.8386356182354735 1.7654044271126772 0.0774958198835586 1.0 0.5848426564173198 4 O15258,O43731,P24390 3 +Autophagosome maturation 0.5695446214062163 1.7653768580669973 0.0775004500841756 1.0 0.5848426564173198 16 O43633,P51809,Q9Y4P8,Q8NHS3,P16615,Q9Y3E7,Q13137,Q96AX1 8 +Endosomal transport 0.4312787009024214 1.7604181069558626 0.0783369414812029 1.0 0.5854923312206598 72 O43633,Q6IAA8,Q13501,O60499,Q96L92,Q15036,P51151,P40616,Q8NBN3,Q92673,Q9UID3,Q99523,Q15904,O95249,Q13190,Q9H223,O15260,O75503,O60826,Q9H4M9,P51149,Q4J6C6 22 +Triglyceride metabolic process 0.625088699364108 1.7598454708342792 0.0784340109788943 1.0 0.5854923312206598 11 Q92673,P04114,P01130,Q8WTV0 4 +Transition metal ion transport 0.56867723212992 1.7598273509172566 0.0784370841448069 1.0 0.5854923312206598 16 Q8NEW0,Q9HC07,P02786,Q04656,O15173,Q9HD20 6 +Mitochondrial genome maintenance 0.6586505258272093 1.7588803252187128 0.0785978376216078 1.0 0.5854923312206598 9 P39210,P12235,Q9BSK2 3 +Negative regulation of amyloid precursor protein biosynthetic process 0.9436227955180364 1.7585445069195145 0.078654905660084 1.0 0.5854923312206598 3 Q9Y287 1 +Organelle fusion 0.5165292617732845 1.7553834380918882 0.0791937430311178 1.0 0.5854923312206598 40 O95249,Q13190,P51809,Q9BZG1,P02786,O60499,O15400,Q9Y6C9,Q14964,Q5SQN1,P51149,Q8IWA4,O60313,Q86Y82,Q13277,P31751,Q9UNK0 17 +Sodium ion transmembrane transport 0.5678665746155219 1.7546379819831313 0.0793212503360967 1.0 0.5854923312206598 16 P55011,P08195,P05023,Q9Y6M7,Q4KMQ2,Q92581,Q96PU5 7 +Carboxylic acid transport 0.5247649706869104 1.7533098463418333 0.0795488362973164 1.0 0.5854923312206598 31 Q96QD8,P98164,P55011,Q15042,P08195,P05556,Q9UBX3,O75915,P30825,Q7L0J3,Q9Y619,P07602,Q9H2D1,Q9NZJ7 14 +Cytokine production 0.3971417554525405 1.7531788452572885 0.0795713130459974 1.0 0.5854923312206598 101 P09601,Q08722,Q8IV08,P62820,P15260,Q96J02,Q9NUD5,P05067,Q5ZPR3,P04062,Q07021,Q92673,P06756,O75787,P01889,Q9NUQ9,Q06481,Q9Y251,Q9Y624,P04439,O75955,Q7KYR7,P15529 23 +Regulation of nervous system development 0.4665775116485687 1.7530260473301915 0.0795975361503134 1.0 0.5854923312206598 62 Q15375,O15031,P98164,Q06481,P53634,Q96G23,Q9NQC3,Q92673,P55209,P01130,Q13641 11 +Myotube differentiation 0.5792084416714288 1.7461622513743118 0.0807827621631416 1.0 0.5854923312206598 15 O75955,P05556,Q99523,Q8IV08,Q9P2K5,Q9H4M9,Q9H7B4 7 +Organelle membrane fusion 0.5247785548071583 1.7438014771911243 0.0811937128224087 1.0 0.5854923312206598 28 O95249,Q13190,P51809,Q9BZG1,O60499,O15400,Q14964,Q5SQN1,P51149,Q8IWA4,Q86Y82,Q13277,P31751,Q9UNK0 14 +Positive regulation of mitochondrion organization 0.524655786247209 1.741520022173988 0.0815924667599172 1.0 0.5854923312206598 22 P12235,Q96A26,P21796,P27544,P11233 5 +Glycosylceramide metabolic process 0.8325998201361511 1.740578483182584 0.0817574919671977 1.0 0.5854923312206598 4 P06280,Q16739 2 +Response to retinoic acid 0.6305261009417302 1.7400833982249309 0.0818443749472126 1.0 0.5854923312206598 10 P02786,P11717 2 +Glycosylation 0.5102294430181431 1.7394270178380358 0.0819596792875887 1.0 0.5854923312206598 43 Q9HC07,P04062,O15118,Q9BV10,P04843,O75503,Q9BT22,Q86SF2,Q10471,P26572,Q10472,Q9BXS4,Q2TAA5,P33908,O43505,Q9H9S5,P46977 17 +Negative regulation of canonical wnt signaling pathway 0.5900291987551913 1.739408905377388 0.0819628629153748 1.0 0.5854923312206598 14 P19022,P48729,O60716,P50402,Q13641 5 +Lactation 0.6113521202627296 1.7375914663139198 0.0822828245698281 1.0 0.5854923312206598 12 P52789,Q9UNS2,Q04656,Q13505,P19021 5 +Positive regulation of synaptic transmission 0.5376164239113007 1.7363127662965727 0.0825085471416702 1.0 0.5854923312206598 18 Q13501,Q15042,Q99538,Q92542,Q13277,P05067 6 +Cell volume homeostasis 0.7242189260591387 1.7358964541110826 0.0825821448933781 1.0 0.5854923312206598 6 P54105,Q4KMQ2,P51790 3 +Intestinal lipid absorption 0.9374158096578732 1.7340785980339068 0.082904138333312 1.0 0.5854923312206598 3 Q16739 1 +Regulated exocytosis 0.5214509633534059 1.7325151248116055 0.0831818865190703 1.0 0.5854923312206598 32 P49755,P20339,P51809,P09601,Q15042,O43760,P16615,Q9BRK5,Q7L0J3,Q5SQN1,P04899,P54920,P11279,Q13277,P0DP25,Q4J6C6 16 +Positive regulation of protein catabolic process in the vacuole 0.936393442622952 1.7300455547554232 0.0836221364962739 1.0 0.5854923312206598 3 Q07954,P01130 2 +Regulation of cell cell adhesion 0.4959733610597582 1.728925582700768 0.0838224147359236 1.0 0.5854923312206598 50 P10644,Q9Y624,Q15375,P02786,Q9NUQ9,P04439,O75955,Q08722,P30825,P15529,O00592,Q96J02,Q5ZPR3 13 +Regulation of neutrophil migration 0.7226293934518742 1.7284363187310154 0.0839100288331096 1.0 0.5854923312206598 6 Q07021,O94813 2 +Regulation of neutrophil chemotaxis 0.7226293934518742 1.7284363187310154 0.0839100288331096 1.0 0.5854923312206598 6 Q07021,O94813 2 +Neutral lipid biosynthetic process 0.7753304026833788 1.7276922846703646 0.0840434075252969 1.0 0.5854923312206598 5 P01130,Q8NCC3 2 +Iron ion homeostasis 0.5362885233840209 1.7271836686323745 0.0841346829036968 1.0 0.5854923312206598 18 P30519,P02786,P09601,Q9Y487,Q8N511,Q15904 6 +Regulation of cell projection organization 0.4062291130672703 1.721254667893381 0.0852046216029167 1.0 0.5854923312206598 115 P20339,Q86VR2,Q16625,Q12834,O00592,O14786,Q96PU5,Q15375,Q9P273,P19022,P98155,P42345,P08069,Q9NQX7,Q9NQC3,Q04656,Q96G23,O94813,Q9HCE1,Q14108,O15031,P10586,Q9H4M9,Q9NV96,Q15555,P07196,Q9Y277,P11233 28 +Amino acid transport 0.5205862330520863 1.720198256932317 0.0853964097794055 1.0 0.5854923312206598 19 Q96QD8,P55011,Q15042,Q15758,P08195,P05556,O75915,P30825,Q7L0J3,Q9Y619,Q6P4A7,O60831 12 +Positive regulation of t cell mediated immunity 0.7199155140785947 1.715687207125229 0.0862193074576813 1.0 0.5854923312206598 6 Q9NUQ9,P04439,O15400,P01889 4 +Mitochondrial cytochrome c oxidase assembly 0.6988028621340541 1.7126611783477328 0.08677489112267 1.0 0.5854923312206598 7 Q15070,Q9Y2R0 2 +Folate transmembrane transport 0.9317224352604868 1.7116080939380047 0.0869689157120801 1.0 0.5854923312206598 3 Q9H2D1 1 +Folic acid transport 0.9317224352604868 1.7116080939380047 0.0869689157120801 1.0 0.5854923312206598 3 Q9H2D1 1 +Digestion 0.6066757631213596 1.710915065643015 0.0870967930384682 1.0 0.5854923312206598 12 Q9Y624,P01130,Q16739 3 +Mitochondrial calcium ion transmembrane transport 0.6738225364844607 1.7106565452606497 0.0871445339710874 1.0 0.5854923312206598 8 O95202,Q8IYU8,P21796 3 +Negative regulation of smooth muscle cell migration 0.7186778057768045 1.7098677303037035 0.0872903348972815 1.0 0.5854923312206598 6 Q07954 1 +Sensory perception of light stimulus 0.5849636417526392 1.7088353028221717 0.0874814613978935 1.0 0.5854923312206598 14 O75569,Q15555,O76024,O60313,P50897,P53611 6 +Fucose metabolic process 0.9297959251925672 1.7039984815185445 0.088381370926557 1.0 0.5854923312206598 3 P04066 1 +Positive regulation of glucose transmembrane transport 0.7173972018748536 1.703843258888398 0.0884103738285362 1.0 0.5854923312206598 6 Q16625 1 +Keratan sulfate metabolic process 0.9285245901639348 1.698975124222342 0.0893238707603147 1.0 0.5883102152274164 3 P16278,P15586 2 +Process utilizing autophagic mechanism 0.4339285850218549 1.6985873524912962 0.0893969611328722 1.0 0.5883102152274164 154 O43633,P20339,Q5T8D3,O75844,Q13501,Q86VR2,Q9Y4P8,Q9UPT5,P09601,P52789,Q9Y6I9,Q14145,P05141,P10619,Q969Q5,P62820,P07602,P21796,Q86UE4,P04062,Q9NNW5,O15118,P17612,O14681,Q93050,Q8NHS3,Q9H0U4,P42345,Q9BXS4,Q86UE8,Q9UID3,Q9NZ45,Q9H9H4,Q15042,P16615,Q07820,Q14964,P49815,Q14596,P27544,Q96HY6,P61421,Q9NZJ7,P51809,P12235,Q9Y487,Q9HB90,O00429,P08754,Q9BWH2,Q13137,Q86Y82,O15269,P51149,P36543 55 +Adp transport 0.8219088225647632 1.6964883034424338 0.089793443409839 1.0 0.5903188876201717 4 P05141,P12235,P12236 3 +Negative regulation of t cell proliferation 0.7679135348299506 1.695056088654516 0.0900647811897432 1.0 0.5904810330458499 5 P10644 1 +Negative regulation of axonogenesis 0.7154422221518377 1.6946397945002298 0.0901437731438377 1.0 0.5904810330458499 6 Q15375,Q9NQC3 2 +Hormone biosynthetic process 0.6462117350725514 1.6940495668857023 0.0902558645848556 1.0 0.5904810330458499 9 P08069,Q14849,P05023,P16435 4 +Trophoblast cell migration 0.8212975307296426 1.693962900432472 0.0902723330437234 1.0 0.5904810330458499 4 P36896 1 +O glycan processing 0.7675627089697026 1.6935101526844822 0.0903584040039804 1.0 0.5904810330458499 5 Q10472,O43505,Q10471 3 +Synaptic vesicle membrane organization 0.7671498877024682 1.69169077710237 0.0907049478575459 1.0 0.5904810330458499 5 O43760,Q13277 2 +Leukocyte degranulation 0.6457556605746634 1.6916644429775118 0.0907099716629769 1.0 0.5904810330458499 9 P11279,P09601 2 +Neuron maturation 0.714787281434573 1.69155478867944 0.0907308930047263 1.0 0.5904810330458499 6 O75503,P05067 2 +Regulation of t cell mediated immunity 0.6938517279856331 1.6886442374758992 0.0912876277353353 1.0 0.5919282735897478 7 Q9NUQ9,P04439,O15400,P01889 4 +Regulation of mast cell activation 0.8198226217930065 1.6878677491197085 0.0914366187785691 1.0 0.5919282735897478 4 P51809,P09601 2 +Regulation of fc receptor mediated stimulatory signaling pathway 0.8198160079750997 1.687840411003002 0.0914418679219322 1.0 0.5919282735897478 4 Q06481 1 +Chondrocyte differentiation 0.6688612214349505 1.6856847045518992 0.0918565444682304 1.0 0.5919282735897478 8 P16435,Q92896,Q9NX62 3 +Hypothalamus development 0.7130636979173282 1.6834319380154823 0.0922915048622394 1.0 0.5919282735897478 6 O14949,O14786,Q15042 3 +Zinc ion homeostasis 0.8186047776963646 1.6828328930275198 0.0924074454645689 1.0 0.5919282735897478 4 Q8NEW0 1 +Angiogenesis involved in wound healing 0.8183010823220638 1.6815770581842968 0.0926508823768359 1.0 0.5919282735897478 4 P43121,P55011,Q9Y251 3 +Regulation of entry of bacterium into host cell 0.8179908455501129 1.6802940558741477 0.0929001170124124 1.0 0.5926734289480236 4 Q9BTY2 1 +Negative regulation of metallopeptidase activity 0.923462043160014 1.6789590140879675 0.0931600318435874 1.0 0.5930218072896288 3 Q92673 1 +Cholesterol storage 0.817645129550661 1.6788641873294827 0.0931785155239179 1.0 0.5930218072896288 4 P04114,Q8WTV0,Q9H4M9 3 +Regulation of anion transport 0.6103526821739487 1.677916889224656 0.0933633249469017 1.0 0.5932881621625806 11 Q7L0J3,P05556,P55011,Q15042 4 +Negative regulation of cell projection organization 0.515668195960763 1.6754459181410335 0.0938467737141599 1.0 0.5946080109274248 28 Q15375,Q9NQX7,Q9NQC3,Q96G23 4 +Branching morphogenesis of a nerve 0.9806620780072118 1.671872807116048 0.09454940601024 1.0 0.5948496685725213 2 Q15375 1 +Retina morphogenesis in camera type eye 0.8158064034978261 1.6712568184781893 0.0946709617270651 1.0 0.5948496685725213 4 P54802,Q15555 2 +Positive regulation of interferon gamma production 0.7623821891560586 1.6706590119802778 0.0947890491965053 1.0 0.5948496685725213 5 P04439,Q5ZPR3 2 +Photoreceptor cell maintenance 0.9209836065573772 1.669152617236176 0.0950871377464788 1.0 0.5948923540444598 3 Q15555,P51790 2 +Vesicle tethering 0.7619349915762648 1.668684442841735 0.0951799338821923 1.0 0.5948975770858961 5 Q14849 1 +Transition metal ion homeostasis 0.5146692862400096 1.6665039081722075 0.0956130904365395 1.0 0.5964523452593773 27 Q8NEW0,P30519,P02786,P09601,Q9Y487,Q04656,Q8N511,Q15904,P05067 9 +Kidney epithelium development 0.5884152119569467 1.664195925649838 0.0960732820358714 1.0 0.5981455848353683 13 Q15375,O00592 2 +Photoreceptor cell development 0.7607238733221666 1.6633352610374272 0.0962453441642414 1.0 0.5981455848353683 5 P54802,Q15555 2 +Synaptic vesicle transport 0.607725752298516 1.663239910643341 0.09626442156287 1.0 0.5981455848353683 11 Q96A57,P14672 2 +Neural retina development 0.6885062403013432 1.6626534128838548 0.0963818326944758 1.0 0.5981455848353683 7 P54802,Q15555,Q8NBN7 3 +Golgi vesicle budding 0.7603937621640962 1.6618768513815771 0.0965374689907112 1.0 0.5981455848353683 5 Q15363,Q9H4A5 2 +Negative regulation of endocytosis 0.5874142405399877 1.6582895042990673 0.0972590464594829 1.0 0.5981455848353683 13 O00560,P05067 2 +Central nervous system neuron development 0.5971972061262973 1.6566229597249855 0.0975957274658869 1.0 0.5981455848353683 12 O14949,Q04656,O94813 3 +Regulation of receptor mediated endocytosis 0.5133603301481796 1.6559127630441948 0.0977394865708485 1.0 0.5981455848353683 25 P50897,O00560,P05067,P06756 4 +Toll like receptor signaling pathway 0.5761721406297273 1.6555514369590587 0.0978126916713033 1.0 0.5981455848353683 14 Q5KU26,Q06481,O75955,Q9NQC3 4 +Diet induced thermogenesis 0.9760734185512944 1.6528891983559728 0.0983534158746799 1.0 0.5981455848353683 2 Q92673 1 +Regulation of stress activated protein kinase signaling cascade 0.512024779431725 1.6525970509959078 0.0984128986671273 1.0 0.5981455848353683 30 O75844,Q53EL6,O00560,O75915,P00533,P08069,P78318,Q96J02,Q14596,P05067 10 +Membrane fusion 0.5021011281130116 1.6484815441613263 0.099253894875005 1.0 0.5981455848353683 41 O95249,Q13190,P51809,Q9BZG1,O60499,Q9P2W9,O15400,O00429,P08754,Q14964,Q5SQN1,P51149,Q8IWA4,Q86Y82,Q92692,Q13277,P31751,Q9UNK0 18 +Cellular copper ion homeostasis 0.7568897637795111 1.6463859805485472 0.0996843175900563 1.0 0.5981455848353683 5 P05067,O60826,Q04656,O75880 4 +Positive regulation of nf kappab transcription factor activity 0.511657197428619 1.6432785739138305 0.1003253092854938 1.0 0.5983628180999899 26 Q86UE4,P02786,O75955,P60900,P05067,Q96HY6 6 +Positive regulation of protein localization to cell surface 0.7561612498862926 1.6431629053598915 0.1003492325227408 1.0 0.5983628180999899 5 Q13277 1 +Lipid import into cell 0.684365026917144 1.642475103462878 0.1004915816092231 1.0 0.5986004064733558 7 P11166 1 +Lymphocyte activation 0.3868935980705046 1.6416554167428 0.1006614360355029 1.0 0.5990517505980476 99 P62942,P05556,Q08722,P05141,Q96J02,Q5ZPR3,P04062,P24390,P02786,Q5HYI8,Q14254,P10644,Q9BXW9,Q9NUQ9,Q04656,Q92542,P30825,Q9NPF0,O96005,P51809,P04439,P15529,P78318,P11279 24 +Regulation of cardiac muscle contraction by calcium ion signaling 0.8084475257842103 1.6407700259688422 0.1008451625291813 1.0 0.5990517505980476 4 P16615,P0DP25 2 +Endochondral bone morphogenesis 0.7038301578697682 1.6398151176534663 0.1010436139188952 1.0 0.5996799435241592 6 O75844,Q9NX62 2 +Cellular response to lipoprotein particle stimulus 0.7548011573598408 1.637143440336571 0.101600501693216 1.0 0.6013396088296694 5 P01130,O15118 2 +Body fluid secretion 0.5835566028708726 1.6354949844977564 0.1019453252402353 1.0 0.6013396088296694 13 P52789,Q9UNS2,Q04656,Q13505,P19021 5 +Response to hepatocyte growth factor 0.8071428621546385 1.6353582908144098 0.1019739605636338 1.0 0.6013396088296694 4 Q99538,Q06481 2 +Cognition 0.5028614542542641 1.634643093058785 0.1021238884074968 1.0 0.6016752587505438 39 P98155,Q99538,Q92542,P14672,P00533,P50897,P17900,P01130,P05067,Q13641 10 +Plasma membrane to endosome transport 0.8063703568393058 1.6321530105232045 0.1026472568087637 1.0 0.6035542600068124 4 Q99523,P61020 2 +Endocytic recycling 0.5085263942525847 1.6299194896876674 0.1031185139239927 1.0 0.6035542600068124 20 Q9H223,Q96L92,O60826,Q15904,P51149,Q92673,Q9H4M9,Q9UID3 8 +Positive regulation of glucose import 0.7529947033329987 1.6291441285443875 0.1032825113352204 1.0 0.6035542600068124 5 Q16625 1 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.53471316983812 1.6231969139504558 0.1045473173509503 1.0 0.603671898269442 17 P98164,Q92896,Q07954,Q92673,Q05D32 5 +Mitochondrial fusion 0.6000142978980951 1.6200318314649322 0.1052254392993772 1.0 0.603671898269442 11 O60313,P02786,Q9Y6C9 3 +Sphingoid metabolic process 0.7502797476810704 1.617112553434491 0.105853987594072 1.0 0.603671898269442 5 Q13510,P04062,O15269 3 +Positive regulation of neural precursor cell proliferation 0.6790384823633566 1.6164669789240085 0.1059933872089546 1.0 0.603671898269442 7 P48681,P98164,P55209 3 +Transcytosis 0.6311846453292169 1.6151686290924017 0.1062741821201465 1.0 0.603671898269442 9 Q07954,P20339,P98164 3 +Endoplasmic reticulum calcium ion homeostasis 0.6307425501343117 1.6128389026187433 0.1067795118156418 1.0 0.603671898269442 9 P16615,P05067,Q96A33 3 +Positive regulation of leukocyte chemotaxis 0.5987288814562732 1.612811820536947 0.1067853972358698 1.0 0.603671898269442 11 Q99538,Q07021,Q4KMQ2 3 +Oligosaccharide lipid intermediate biosynthetic process 0.7489456628239493 1.611196401860056 0.1071369218162017 1.0 0.603671898269442 5 Q9BT22,Q9BV10 2 +Detection of stimulus 0.5688121867396337 1.6107311605082086 0.1072383309147864 1.0 0.603671898269442 14 P01889,Q8WTV0,P04439,Q15555,P0DP25 5 +Sarcoplasmic reticulum calcium ion transport 0.6971382241702092 1.6080996016215194 0.1078133664584526 1.0 0.603671898269442 6 P16615,O75844,P0DP25 3 +Fc gamma receptor signaling pathway 0.6970155693521132 1.607517491531834 0.1079408954974987 1.0 0.603671898269442 6 Q06481 1 +Substrate dependent cell migration cell extension 0.6968170333833146 1.6065751947053135 0.1081475875587503 1.0 0.603671898269442 6 O00560 1 +Regulation of bone mineralization 0.6767771108557068 1.6054070924215518 0.1084042445917745 1.0 0.603671898269442 7 O75844,Q14596,Q4KMQ2 3 +Positive regulation of leukocyte mediated immunity 0.5057414713787949 1.6037447754656684 0.108770321897712 1.0 0.603671898269442 22 P02786,Q9NUQ9,P04439,O15400,P11279 5 +Muscle cell migration 0.5672817382423692 1.6013871728568296 0.1092911920056891 1.0 0.603671898269442 14 Q04656,Q07954,O15511,O94813,Q13685,Q92673,O14786 7 +Protein processing 0.4889580498051266 1.6012314426519 0.109325667127391 1.0 0.603671898269442 46 O75844,O75976,O75787,P42892,P16870,O75503,Q99538,Q9UG56,Q92896,Q92542,Q15005,Q9BXS4,P67812,Q9H9S5 14 +Protein lipid complex assembly 0.7462360573921807 1.599172261290767 0.1097823319649724 1.0 0.603671898269442 5 P04114,P17612 2 +Cellular response to inorganic substance 0.5003058290336019 1.5972772263957424 0.110203924902555 1.0 0.603671898269442 37 P09601,Q99538,Q04656,Q6NUK1,Q92542,P00533,O95831,P05067 8 +Phosphatidylethanolamine metabolic process 0.9026229508196734 1.5963684733048245 0.1104065506206297 1.0 0.603671898269442 3 P35790,Q8NCC3 2 +Positive regulation of neuron projection development 0.5049055327979869 1.5957847038155304 0.1105368695339683 1.0 0.603671898269442 29 O15031,Q9P273,Q86VR2,Q9UQB8,P98155,Q9NV96,P08069,Q13308,Q14108,Q9H4M9 10 +Cellular response to mineralocorticoid stimulus 0.797247601173068 1.5942495067844622 0.1108801620934363 1.0 0.603671898269442 4 O95831,P20020 2 +Glycosphingolipid biosynthetic process 0.9613241560144254 1.5918245816821075 0.1114241252019057 1.0 0.603671898269442 2 Q99805 1 +Regulation of receptor recycling 0.6739482372127676 1.59155659504138 0.1114843694028975 1.0 0.603671898269442 7 P01130,P42892 2 +Enzyme linked receptor protein signaling pathway 0.4047837084348925 1.589729048176018 0.1118958930166906 1.0 0.603671898269442 126 P62942,Q9UIQ6,P05556,O95470,Q15043,O14654,P36896,O14786,Q15375,Q92572,Q53EL6,O00560,P14672,P08069,Q92673,Q9NQC3,Q9UQB8,P98164,Q99538,Q06481,Q99523,P00533,P04899,Q05D32,P10586,Q92896,P11717,Q07954,P51149,O00400,P31751,P43490 32 +Regulation of endoplasmic reticulum tubular network organization 0.7957249361330058 1.587914095984872 0.1123057655709094 1.0 0.603671898269442 4 Q6DD88,Q15042 2 +Apoptotic cell clearance 0.6256392338537877 1.585909051873717 0.1127599421531198 1.0 0.603671898269442 9 Q07954,P06756,Q08431 3 +Long term synaptic potentiation 0.6022277273913914 1.585771825371789 0.1127910791449271 1.0 0.603671898269442 10 Q99538,Q13277,Q13501,P05067 4 +Regulation of lipase activity 0.5641115833520866 1.582006263793316 0.1136481405546745 1.0 0.603671898269442 14 Q07954,P50897,Q99523,P00533 4 +Acute phase response 0.9587020648967592 1.5809630082246124 0.1138864960759042 1.0 0.603671898269442 2 P02786 1 +Neuron projection regeneration 0.5926827838498367 1.578784921495262 0.1143853983304978 1.0 0.603671898269442 11 P07196,P00374,Q96G23,P10586 4 +Mononuclear cell migration 0.502566027411756 1.5755920477831031 0.1151198499770298 1.0 0.603671898269442 25 Q9Y624,P04062,P55011,Q99538,Q08722,O94813,Q4KMQ2,P05067 8 +Receptor internalization 0.501513282123108 1.575569278530692 0.1151251008402274 1.0 0.603671898269442 21 P20339,P02786,O75955,P05556,O00560,Q07954 6 +Negative regulation of lipid localization 0.7404231981867035 1.5733412018094588 0.1156398338492197 1.0 0.603671898269442 5 P06756 1 +Mitochondrial fission 0.5729698503347636 1.572683089439185 0.1157922174088601 1.0 0.603671898269442 13 Q9NUQ9,Q9UDX5,P11233 3 +Mitochondrial electron transport cytochrome c to oxygen 0.689055758972774 1.5696802043829237 0.1164895288251977 1.0 0.603671898269442 6 P13073,Q7KZN9 2 +Torc1 signaling 0.6459261559655578 1.569475886437086 0.1165370938809204 1.0 0.603671898269442 8 Q8NHS3,Q9HB90,P42345 3 +Proton transporting v type atpase complex assembly 0.895737704918034 1.5690183333026422 0.1166436672258637 1.0 0.603671898269442 3 Q9P0T7,Q8N511 2 +Positive regulation of oxidoreductase activity 0.5985299326411795 1.5654345685701947 0.1174810482396038 1.0 0.603671898269442 10 P00374,Q8WTV0,Q04656,P16435,P04899,P0DP25 6 +Glomerular basement membrane development 0.8947801587685194 1.5652125300921105 0.1175330844814732 1.0 0.603671898269442 3 P14543 1 +Regulation of fc gamma receptor signaling pathway involved in phagocytosis 0.9544411668305488 1.5633104458666305 0.1179795925134019 1.0 0.603671898269442 2 Q06481 1 +Central nervous system neuron differentiation 0.538258081962787 1.5632734040513168 0.1179883011499876 1.0 0.603671898269442 16 O14949,Q04656,O14786,O94813 4 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.8940983606557321 1.562502389934109 0.1181696832901821 1.0 0.603671898269442 3 P04439,P10321 2 +Regulation of response to osmotic stress 0.7895364561110404 1.5621399911896892 0.1182550136247608 1.0 0.603671898269442 4 O95202 1 +Diencephalon development 0.6679210149293562 1.5619915329907736 0.118289983513028 1.0 0.603671898269442 7 O14949,O14786,Q15042 3 +Positive regulation of organic acid transport 0.7377989282941936 1.5616638042725262 0.1183672099625079 1.0 0.603671898269442 5 P55011,Q15042 2 +Iron ion transport 0.5895920446611869 1.5613484611953117 0.1184415551640609 1.0 0.603671898269442 11 Q8N4V1,P02786,Q04656,O15173 4 +Walking behavior 0.7890409751153735 1.560074655497783 0.1187422400335309 1.0 0.603671898269442 4 O75844 1 +Lipid translocation 0.7887494303490927 1.5588592786353004 0.1190296902276446 1.0 0.603671898269442 4 Q9NV96 1 +Positive regulation of biomineralization 0.7884805901461474 1.557738474322488 0.1192952560878319 1.0 0.603671898269442 4 P04920,Q4KMQ2 2 +Triglyceride catabolic process 0.95280235988201 1.5565203262013243 0.1195844130903438 1.0 0.603671898269442 2 Q92673 1 +Small gtpase mediated signal transduction 0.3735928109812397 1.556479690034287 0.1195940685255791 1.0 0.603671898269442 91 Q15392,Q13501,P09601,P80303,P05556,O14786,O00560,Q5HYI8,Q9H0H5,P06756,Q02818,Q9NUQ9,Q14964,O94813,Q9Y624,Q9P035,Q9HB90,O75955,Q15555,Q96AG4,P57105,P11233 22 +Ceramide transport 0.7365095076840729 1.5559226643072184 0.1197264832754712 1.0 0.603671898269442 5 P07602 1 +Metencephalon development 0.4998527540533189 1.5557420796937 0.119769436035392 1.0 0.603671898269442 28 P54802,O14949,Q04656,Q92542,Q9BRK5,Q5KU26 6 +Cellular response to peptide 0.3930289120460792 1.5546441739164591 0.1200308370527352 1.0 0.6042641905791004 77 Q15043,O14654,P08670,P05067,Q92572,P56192,P14672,P08069,Q92673,P20020,Q9UQB8,Q99538,Q06481,P04899,P49815,Q9BSK2,Q07954,P16435,Q96A49,P31751,P43490 21 +Vesicle targeting to from or within golgi 0.5690328036927654 1.549230740313284 0.1213262622779152 1.0 0.6066476031777972 13 P49755,Q15363,Q9HCU5,Q9Y6B6,Q9NR31 5 +Insulin like growth factor receptor signaling pathway 0.6846866155593142 1.5488614511893777 0.1214150294255773 1.0 0.6066476031777972 6 P08069,P49815,P11717 3 +Oxidative phosphorylation 0.4516681382666653 1.5473152293374404 0.1217872511653341 1.0 0.6069658919788496 60 O14949,Q9H3K2,P13073,O75964,P14406,Q04656,P09622,O96000,Q9Y6M9,Q7KZN9,P00403,Q9UDW1,O43676,Q9BSK2,P03886,O75438,O95169,P03915 18 +Positive regulation of response to external stimulus 0.4454506647015461 1.5425816451981995 0.1229323142908549 1.0 0.6100087589223279 62 P51809,P11279,Q53EL6,Q99538,Q07021,Q08722,P53634,Q99735,Q92692,P01130,O94813,Q4KMQ2,Q9NUD5,Q13277,O14786,P05067,Q13641 17 +Maintenance of blood brain barrier 0.6406271123686739 1.542452865285962 0.1229635834958595 1.0 0.6100087589223279 8 Q9Y624,P55011,Q16625 3 +Vesicle targeting rough er to cis golgi 0.5860071309369219 1.5410890090811054 0.1232951244533158 1.0 0.6107168147691423 11 P49755,Q15363,Q9HCU5,Q9Y6B6,Q9NR31 5 +Dendrite extension 0.6829404046339232 1.5405311802692974 0.123430928486983 1.0 0.6109217110805608 6 Q7L576,O60271,Q92581,Q96PU5 4 +Positive regulation of nitric oxide synthase activity 0.7837259788805617 1.537904292587999 0.1240720175904508 1.0 0.6131565177942143 4 Q8WTV0,P0DP25 2 +Regulation of calcium ion dependent exocytosis 0.7320111232686123 1.535875812783462 0.1245688413181689 1.0 0.6146726426294696 5 P16615,P04899,Q15042 3 +Cell activation 0.402160423992508 1.5353781926485257 0.124690957209202 1.0 0.6148062516664088 128 P09601,P62942,P05556,Q08722,P05141,P15260,Q96J02,P05067,Q5ZPR3,P04062,P24390,P02786,P53634,Q5HYI8,Q14254,P01130,P10644,Q9BXW9,Q9NUQ9,Q04656,Q92542,P30825,Q9NPF0,Q92692,O96005,Q9Y624,P51809,P04439,Q07954,P15529,P78318,Q9BWH2,P11279 33 +Biomineralization 0.5562124399870612 1.5335649866206835 0.1251367076059026 1.0 0.616064963091769 14 Q14596,O75844,P04920,Q4KMQ2 4 +Embryonic pattern specification 0.6618309889860587 1.53204388976289 0.1255116044947746 1.0 0.6163409133943354 7 Q15363,Q9Y2W6 2 +Cellular hyperosmotic response 0.6810288220112226 1.531405766918968 0.1256691397073934 1.0 0.6163409133943354 6 O95202,P11166 2 +Glycolipid transport 0.8855737704918004 1.5285967919067387 0.1263644318192893 1.0 0.6167660295119965 3 P61916,P07602 2 +Positive regulation of regulated secretory pathway 0.7814882720644265 1.528561824291388 0.1263731060240753 1.0 0.6167660295119965 4 P11279 1 +Negative regulation of immune effector process 0.6147235665738775 1.5280854786672575 0.1264913163853549 1.0 0.6167660295119965 9 P15529,P04439,Q08722,P09601 4 +Neutral amino acid transport 0.7300661502646107 1.5271996982306897 0.1267113613384152 1.0 0.6167660295119965 5 P08195,Q96QD8,Q15758 3 +Protein insertion into er membrane 0.5747476709808511 1.5268889871781088 0.1267886185163218 1.0 0.6167660295119965 12 Q8N4V1,Q15629 2 +Vesicle targeting 0.4951219795902245 1.5230976890612644 0.1277342669364847 1.0 0.6171572518844014 23 P49755,O95772,Q14849,Q15363,Q9HCU5,O00743,Q9Y6B6,Q9NR31 8 +Natural killer cell activation 0.6361540461187931 1.5195934725853963 0.1286131794485816 1.0 0.6171572518844014 8 Q5HYI8,P51809,P11279 3 +Detection of external biotic stimulus 0.883278688524592 1.519462325501956 0.1286461642073086 1.0 0.6171572518844014 3 P04439,P01889 2 +Phagocytosis recognition 0.8832786885245894 1.5194623255019464 0.1286461642073111 1.0 0.6171572518844014 3 Q5KU26,Q08431 2 +Phosphatidylcholine catabolic process 0.8832786885245895 1.5194623255019464 0.1286461642073111 1.0 0.6171572518844014 3 P01130,Q8NCC3 2 +Tor signaling 0.494219588987346 1.5189578336476215 0.1287731100705555 1.0 0.6171572518844014 22 P04062,O75844,Q6IAA8,Q8NHS3,Q9HB90,Q9NWS0,P42345,P49815,Q96A49 9 +Positive regulation of mitochondrial calcium ion concentration 0.727847138755707 1.5172950658415696 0.1291922034194592 1.0 0.6171572518844014 5 Q9BPX6,Q8IYU8 2 +Cardiac septum morphogenesis 0.6777611406267032 1.5157917665440717 0.129572014626804 1.0 0.6171572518844014 6 O94813,P98164 2 +Regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.4929759628934105 1.5118256930959235 0.130578211355604 1.0 0.6171572518844014 32 Q92896,O00560,Q07954,Q92673,P36896 5 +Endosome to plasma membrane protein transport 0.7772636119866859 1.510910766738159 0.1308111873238486 1.0 0.6171572518844014 4 Q15904 1 +Ornithine transport 0.94133071124222 1.5089840902982714 0.1313028485784579 1.0 0.6171572518844014 2 P30825 1 +Nervous system process 0.3776379708341334 1.508593943524007 0.1314025828654295 1.0 0.6171572518844014 100 O75844,Q9Y6M9,P05067,P04062,P98155,P53634,P14672,P50897,P01130,Q13641,P98164,Q15042,Q99538,Q92542,P07686,P00533,Q14108,P17900,O00264,P10253,Q15555,O14773,O76024 23 +Membrane protein intracellular domain proteolysis 0.8803278688524538 1.5077145818042996 0.1316275918593108 1.0 0.6171572518844014 3 Q92542,Q8TCT8 2 +Regulation of alcohol biosynthetic process 0.7763261113258919 1.5069915405707155 0.1318128255649044 1.0 0.6171572518844014 4 P04114 1 +Regulation of cholesterol biosynthetic process 0.7763261113258919 1.5069915405707155 0.1318128255649044 1.0 0.6171572518844014 4 P04114 1 +Regulation of golgi organization 0.6566300693261566 1.5064107376565024 0.1319617659290193 1.0 0.6171572518844014 7 Q9P2W9 1 +Golgi organization 0.4686255280600299 1.5035752996242988 0.1326907550370895 1.0 0.619766421902478 51 Q9P2W9,P62820,Q9BTU6,P40616,Q9H4A5,Q6DD88,Q14789,P49257,Q7Z3D4,Q9UID3,Q8TBA6,Q9Y3B3,Q7RTS9,P61019,Q5VU43,P49755,Q13190,O15260,Q12907,Q15363,Q8NHH9 21 +Neuron development 0.434877980825862 1.502339833337276 0.1330093662981317 1.0 0.6197813346017047 178 Q9Y6M7,Q13277,O14786,P05067,Q96PU5,P54802,P04062,Q15375,P98155,Q8NHS3,P50897,P07942,Q9NQX7,Q9NQC3,Q13641,O14949,P98164,Q06481,Q04656,Q96G23,O94813,Q9HCE1,Q14108,Q92581,O00264,Q9NZJ7,O15031,P35613,P42892,P10586,O75503,Q9NV96,O75955,Q15555,Q8NBN7,Q16739,Q9H4M9 37 +Regulation of microglial cell activation 0.9387086201245494 1.498118511676435 0.1341024623229882 1.0 0.6215411861255913 2 P53634 1 +Regulation of t cell activation 0.4880032551939369 1.498045726468787 0.134121370535891 1.0 0.6215411861255913 37 P10644,P02786,Q9NUQ9,P04439,Q08722,P30825,P15529,O96005,Q5ZPR3 9 +Positive regulation of cholesterol storage 0.8770491803278714 1.4946572900912665 0.1350039061733241 1.0 0.6215411861255913 3 P04114,Q8WTV0 2 +Vasculogenesis 0.6542303400131049 1.4945659881548423 0.1350277481718322 1.0 0.6215411861255913 7 P06756 1 +Retina development in camera type eye 0.5155139891422972 1.4936857179846172 0.1352577831845887 1.0 0.6215411861255913 17 P54802,Q8NF37,Q15555,Q8NBN7,O14786,P20020 6 +Retrograde transport endosome to golgi 0.4895502206820837 1.49304480472877 0.1354254590742716 1.0 0.6215411861255913 34 O95249,Q13190,O60499,O75503,Q8NBN3 5 +Lipoprotein catabolic process 0.6535653288834791 1.4912816562051334 0.1358875629369142 1.0 0.6215411861255913 7 P04114,P50897 2 +Positive regulation of cell adhesion molecule production 0.8758925545050447 1.4900500548161904 0.1362110751680543 1.0 0.6215411861255913 3 Q5KU26 1 +Cell adhesion molecule production 0.8758925545050447 1.4900500548161904 0.1362110751680543 1.0 0.6215411861255913 3 Q5KU26 1 +Cerebellar cortex morphogenesis 0.7215033630940009 1.4889445348722268 0.1365019749030571 1.0 0.6215411861255913 5 Q04656 1 +Cerebellar cortex formation 0.7215033630940009 1.4889445348722268 0.1365019749030571 1.0 0.6215411861255913 5 Q04656 1 +Negative regulation of low density lipoprotein receptor activity 0.9364142903965986 1.488611470243027 0.1365897094054076 1.0 0.6215411861255913 2 P05067 1 +Regulation of macrophage derived foam cell differentiation 0.9364142903965909 1.4886114702429951 0.136589709405416 1.0 0.6215411861255913 2 P04114 1 +Regulation of defense response to virus 0.5381312119093801 1.4879878468110386 0.1367540987130913 1.0 0.6215411861255913 15 Q96J02,O75844,Q07021,O43657 4 +Positive regulation of inflammatory response 0.5579020154598127 1.482661119495683 0.1381644695866684 1.0 0.6226543223861001 13 P51809,P53634,Q08722,Q99735,P01130,P05067 6 +Regulation of steroid biosynthetic process 0.5835050673605374 1.4824094902460483 0.1382313703219613 1.0 0.6226543223861001 10 P04114,P05023,P16435,Q13510 4 +Sterol import 0.8737704918032803 1.4815958717358098 0.1384478581453012 1.0 0.6226543223861001 3 P01130,Q8WTV0 2 +Excretion 0.6703417229211953 1.4802712918085663 0.138800861390427 1.0 0.6226543223861001 6 Q96J84,P09601 2 +Protein containing complex remodeling 0.8733567501922974 1.479947360647414 0.1388872951099047 1.0 0.6226543223861001 3 P04114 1 +Regulation of exocytosis 0.486480763614315 1.4792794646655585 0.1390656389173123 1.0 0.6226543223861001 36 O43633,P20339,P51809,P09601,Q15042,Q8WUM4,P16615,O00560,P04899,P0DP25,P11279,P51149,P11233,Q4J6C6,P51151 15 +Calcium ion import into sarcoplasmic reticulum 0.9341199606686332 1.4791049107641026 0.1391122779345028 1.0 0.6226543223861001 2 O75844 1 +Vascular wound healing 0.8731147540983549 1.4789831244844402 0.1391448251151075 1.0 0.6226543223861001 3 P43121,Q9Y251 2 +Regulation of membrane permeability 0.5005695778143778 1.478634892227662 0.1392379219580624 1.0 0.6226543223861001 18 Q9Y624,P52789,P12235,P45880,P05141,P42345 6 +Cellular response to copper ion 0.9337921992789326 1.4777468794892128 0.1394755414513939 1.0 0.6226543223861001 2 P05067 1 +Cellular response to iron ion 0.9337921992789248 1.4777468794891788 0.139475541451403 1.0 0.6226543223861001 2 P09601 1 +Cellular response to estradiol stimulus 0.6695655616123506 1.476550077115212 0.1397962823075085 1.0 0.6226543223861001 6 O95831,P00533 2 +Glycerolipid biosynthetic process 0.4824467950356475 1.4762279823015367 0.139882699990882 1.0 0.6226543223861001 40 Q8NF37,Q96N66,Q8WTV0,Q8NCC3,Q9UG56,Q9UBF8,Q9NX62,O43292,Q9NTJ5,Q9BTU6,Q9NPH0,O14735,Q92643,P48651,P35790,Q9H490,P01130 17 +Macromolecule depalmitoylation 0.6694457605392001 1.4759756163818254 0.1399504382051923 1.0 0.6226543223861001 6 Q9UMR5 1 +Export from cell 0.3943325500920737 1.473223767902925 0.1406907082395216 1.0 0.6229849909329489 124 O43633,P20339,Q9UPT5,P09601,P55011,P05023,Q9BRK5,Q5SQN1,Q86YV9,P62820,P54920,Q13277,P51151,Q9UBV2,Q9H4A5,O00186,P27824,O00560,Q16850,P50897,P0DP25,P20645,P19021,P20020,P16870,Q15042,O15126,Q7Z6M1,P16615,Q7L0J3,P04899,Q96KC8,Q9HCU5,P49755,P51809,P54709,Q15758,Q8WUM4,O43760,O00429,Q32P28,Q4KMQ2,P11279,P51149,P11233,Q4J6C6 46 +Maternal placenta development 0.6688511108658196 1.4731238497452062 0.1407176435892558 1.0 0.6229849909329489 6 P07858,P35613 2 +Response to dietary excess 0.8712047854226763 1.471372138816765 0.1411905038821461 1.0 0.6229849909329489 3 Q92673 1 +Nucleobase transport 0.871147540983603 1.4711440083288685 0.1412521756509863 1.0 0.6229849909329489 3 Q9Y277,P12235 2 +Mitochondrial adp transmembrane transport 0.8711475409835948 1.4711440083288354 0.1412521756509952 1.0 0.6229849909329489 3 P12235,P12236 2 +Negative regulation of oxidoreductase activity 0.8702729947327714 1.4676586370521174 0.1421969715872133 1.0 0.6242408940806116 3 Q15070 1 +Nerve development 0.6259460689254254 1.4672650472902682 0.1423039680396338 1.0 0.6242408940806116 8 Q9H061,P42892 2 +Aminophospholipid transport 0.9305145853818464 1.4641673917623754 0.1431482174082483 1.0 0.6250520271545451 2 Q9NV96 1 +Jnk cascade 0.4985128948454341 1.4641567976869598 0.1431511113463786 1.0 0.6250520271545451 18 Q53EL6,Q9P035,O00560,P00533,P08069,Q96J02,P05067 7 +Smad protein signal transduction 0.6027108353310808 1.464113644723022 0.1431628997202283 1.0 0.6250520271545451 9 Q07954,Q9UIQ6,O00400,P08670 4 +Positive regulation of autophagy of mitochondrion 0.666892188576384 1.4637253448243146 0.1432690076187339 1.0 0.6250520271545451 6 P27544,P12235,P21796 3 +Protein o linked glycosylation via serine 0.8688406383851377 1.4619496837896506 0.1437549985904205 1.0 0.6250520271545451 3 Q10472 1 +Tolerance induction 0.7651234026019793 1.4600988054228576 0.1442629208918293 1.0 0.6263334464760026 4 Q96J02 1 +Receptor localization to synapse 0.5713227010651146 1.4577209201753367 0.1449174831732027 1.0 0.6279110506680835 11 O15400,Q13277 2 +T cell differentiation 0.4861866185918795 1.454310089855773 0.1458603543383196 1.0 0.6288131564475405 24 P24390,Q04656,Q5HYI8,P15529,O96005 5 +Manganese ion transmembrane transport 0.8668852459016313 1.454155080800173 0.1459033154780891 1.0 0.6288131564475405 3 Q9HC07,Q9HD20 2 +Manganese ion transport 0.8668852459016313 1.454155080800173 0.1459033154780891 1.0 0.6288131564475405 3 Q9HC07,Q9HD20 2 +Semaphorin plexin signaling pathway involved in neuron projection guidance 0.865573770491791 1.4489266681609685 0.1473580627283921 1.0 0.6316842772150227 3 O15031,P42892 2 +Protein deneddylation 0.6449588514231328 1.4487027468680806 0.1474206130413591 1.0 0.6316842772150227 7 Q99627,Q9BT78 2 +Regulation of establishment or maintenance of cell polarity 0.6448683243887643 1.4482541703767189 0.1475459797297726 1.0 0.6316842772150227 7 Q9NUQ9 1 +Phosphatidylserine metabolic process 0.6633433295482217 1.446682925185508 0.1479857488493747 1.0 0.632028606845286 6 Q9NRX5,P48651,Q8NCC3 3 +Decidualization 0.9259259259259348 1.445159304989496 0.1484131441327905 1.0 0.6324548437546443 2 P07858 1 +Skeletal system morphogenesis 0.5083253527854463 1.4448212473910065 0.1485081013546614 1.0 0.6324548437546443 17 O75844,O75386,Q92896,Q9NX62,O95470,P16435 6 +Regulation of macroautophagy 0.4578787201769708 1.4429316813884665 0.1490397174693432 1.0 0.6334320538600581 53 P04062,O15118,P17612,P09601,Q15042,Q93050,P12235,Q9Y487,P05141,P36543,P42345,P08754,Q13137,P49815,O15269,P21796,P27544,P61421 18 +Synaptic vesicle priming 0.7607674476446771 1.4418375937570245 0.1493481947084936 1.0 0.6334320538600581 4 Q7L0J3,Q5SQN1 2 +Regulation of synaptic transmission glutamatergic 0.7607072183282022 1.4415849958529987 0.1494194836939435 1.0 0.6334320538600581 4 Q15042 1 +Negative regulation of receptor binding 0.924942641756801 1.4410867414792383 0.149560178753846 1.0 0.6334320538600581 2 P16615 1 +Regulation of cell adhesion 0.3699871642904584 1.4404009256453445 0.1497540019530903 1.0 0.6334320538600581 97 Q08722,O00592,Q96J02,Q13277,P07237,O14786,Q5ZPR3,Q15375,P02786,Q07021,P10644,P06756,Q9NUQ9,P30825,Q9Y624,O15031,P04439,O75955,P15529,P14543 20 +Neuron projection extension involved in neuron projection guidance 0.8633816515285813 1.4401864311463857 0.1498146610613524 1.0 0.6334320538600581 3 O94813 1 +Regulation of tube size 0.5755146556664196 1.4380100699105676 0.1504311969748109 1.0 0.6352084942754906 10 Q9HB40,P42892 2 +Camera type eye photoreceptor cell differentiation 0.9229760734185508 1.4329423515133002 0.1518743127409021 1.0 0.6400488137595413 2 P54802 1 +Retinal rod cell differentiation 0.9229760734185508 1.4329423515133002 0.1518743127409021 1.0 0.6400488137595413 2 P54802 1 +Retinal rod cell development 0.9229760734185508 1.4329423515133002 0.1518743127409021 1.0 0.6400488137595413 2 P54802 1 +Fc receptor signaling pathway 0.6191276325446656 1.432192351785736 0.1520887799610344 1.0 0.6405353629999555 8 Q06481 1 +Endosomal lumen acidification 0.9223205506391424 1.4302277882106755 0.1526516524312104 1.0 0.642069921701886 2 Q9P0T7 1 +Neuron cellular homeostasis 0.708276596099513 1.42967731692909 0.1528096534207907 1.0 0.6421569599035847 5 P51790 1 +Regulation of smoothened signaling pathway 0.5962304834099006 1.4294641239656771 0.1528708793092472 1.0 0.6421569599035847 9 P16435,O75386,Q9BZG1,P17612 4 +Pyramidal neuron development 0.8605143294188284 1.428752376045751 0.1530754180252591 1.0 0.6421821525326857 3 O14949 1 +Water homeostasis 0.595581008619324 1.4259862854834122 0.1538723008342568 1.0 0.6442717890594224 9 P04062,Q96PU5,O76024,Q16739 4 +Atp synthesis coupled electron transport 0.4790784996627279 1.4255424958285603 0.154000445177076 1.0 0.6443912547545309 37 O14949,Q9H3K2,P09622,O96000,Q9Y6M9,Q7KZN9,P00403,Q9UDW1,O43676,P03886,O75438,P13073,P03915 13 +Mast cell activation 0.6399686923581988 1.423954284666812 0.1544597060385162 1.0 0.6458951767053402 7 P51809,P09601 2 +Response to thyroglobulin triiodothyronine 0.9206817436906009 1.4234419295011969 0.1546080848552147 1.0 0.646097998015752 2 P16278 1 +Regulation of membrane invagination 0.9203539823008924 1.4220848561279356 0.1550016185208556 1.0 0.6469067549751406 2 Q06481 1 +Negative regulation of cell volume 0.9203539823008854 1.4220848561279071 0.1550016185208638 1.0 0.6469067549751406 2 P51790 1 +Sphingosine biosynthetic process 0.7557195833370925 1.4206579475581436 0.1554162233910754 1.0 0.64780125587427 4 P04062,Q13510 2 +Positive regulation of adaptive immune response 0.5157738334453723 1.4157139796217977 0.1568592636781443 1.0 0.6502696921652784 16 P02786,P01889,Q9NUQ9,P04439,O15400 5 +Potassium ion homeostasis 0.7543456871105182 1.4148902775102656 0.1571006690515033 1.0 0.6502696921652784 4 P54709,P05023,P55011 3 +Potassium ion import across plasma membrane 0.7543456871105182 1.4148902775102656 0.1571006690515033 1.0 0.6502696921652784 4 P54709,P05023,P55011 3 +Regulation of neurogenesis 0.4481661751207438 1.414203137918968 0.1573022669141395 1.0 0.6502696921652784 56 Q15375,O15031,P98164,Q06481,Q96G23,Q9NQC3,Q92673,P55209,P01130 9 +Response to leptin 0.7048271003053528 1.414188350538515 0.1573066074941875 1.0 0.6502696921652784 5 Q16739 1 +Transmembrane receptor protein serine threonine kinase signaling pathway 0.4605002139217643 1.4127274968974564 0.1577358634242076 1.0 0.6502696921652784 50 Q9UIQ6,Q06481,O00560,Q92896,Q07954,Q92673,P36896 7 +Protein targeting to mitochondrion 0.4725267998816531 1.412121774482573 0.1579141083882524 1.0 0.6502696921652784 42 Q9NS69,Q8N4H5,O96008,P51572,O60830,P55786,Q3ZCQ8,O14925,O95831,Q9P0J0,Q9Y512,Q15388,Q53H12,Q99595 14 +Positive regulation of osteoblast proliferation 0.7534006551843541 1.4109222514432498 0.1582675402804936 1.0 0.6502696921652784 4 P06756,Q9Y251 2 +Phosphatidylinositol biosynthetic process 0.4791518703540161 1.4109094384853242 0.1582713187683189 1.0 0.6502696921652784 21 Q96N66,Q9NX62,O43292,Q9BTU6,O14735,Q92643,Q9UBF8,Q9H490 8 +Phosphatidylinositol metabolic process 0.4791518703540161 1.4109094384853242 0.1582713187683189 1.0 0.6502696921652784 21 Q96N66,Q9NX62,O43292,Q9BTU6,O14735,Q92643,Q9UBF8,Q9H490 8 +Positive regulation of blood circulation 0.8558169661114918 1.4100171384094653 0.1585346223896584 1.0 0.6506251516503045 3 P16615 1 +Response to light intensity 0.917076368403802 1.4085160801340462 0.1589783088786727 1.0 0.6516923812397514 2 Q8NBN7 1 +Regulation of systemic arterial blood pressure by hormone 0.8536145760536846 1.4012317915558372 0.1611447703785216 1.0 0.652673289320581 3 P42892 1 +Positive regulation of cell population proliferation 0.3872576195447772 1.40037033821864 0.1614024476085518 1.0 0.652673289320581 122 P09601,P05141,Q08722,Q13277,Q5ZPR3,P02786,P43307,O00560,P07942,Q9NQC3,P06756,P98164,Q99538,Q04656,P30825,P00533,P55209,Q96HY6,Q9Y251,Q9BSK2,P04439,P15529,P31751,P43490 24 +Regulation of programmed necrotic cell death 0.6127753705864962 1.3994354806696527 0.1616824333750735 1.0 0.652673289320581 8 P12235 1 +Renal system process 0.5529021655754556 1.3991991261128127 0.1617532785760531 1.0 0.652673289320581 12 P17612,Q99538,P43121,O76024,Q96J84 5 +Regulation of synaptic vesicle exocytosis 0.5904079628495835 1.3982525785140256 0.1620372327701447 1.0 0.652673289320581 9 P20339,P16615,Q15042,P0DP25 4 +Cellular iron ion homeostasis 0.5341603685451013 1.3972581374776123 0.1623359595790408 1.0 0.652673289320581 14 P02786,P09601,Q9Y487,Q8N511,Q15904 5 +Secondary alcohol metabolic process 0.4694637715160381 1.396455469452681 0.16257738133245 1.0 0.6528333819608306 43 Q15392,P61916,P04114,P05067,Q14534,P04062,O15118,P98155,Q16850,P35610,Q14849,P01130,P00387,Q15800,Q9H2C2,Q14739,Q8WTV0,P14324,P16435,Q9BQE5 20 +Regulation of mast cell activation involved in immune response 0.8524170758587428 1.3964546997282086 0.16257761297556 1.0 0.6528333819608306 3 P09601 1 +Regulation of hormone levels 0.4413276341500942 1.394461993671653 0.1631781387887803 1.0 0.6539921503435505 58 Q6NUM9,O75844,P51809,O75787,P42892,P16870,Q8TC12,P05023,Q9HB40,O95470,Q14849,P62820,P08069,Q53GQ0,P16435,Q8NBN7,Q15043,P07858 18 +Response to chemokine 0.7494090577203154 1.3941557705965733 0.1632705708463184 1.0 0.6539921503435505 4 O94813 1 +Homologous chromosome pairing at meiosis 0.5892067716940309 1.3918045516174558 0.1639815912926379 1.0 0.6552173650846662 9 Q92791,Q9BTX1,Q9BXW9 3 +Regulation of cytosolic calcium ion concentration 0.476380052673038 1.3903473478021848 0.1644234266263537 1.0 0.6561722065674785 21 Q14344,P06756,P17612,P62942,P0DP25,O95202,P20020 7 +Positive regulation of cell activation 0.4659528504558127 1.3891501415662997 0.1647870991858604 1.0 0.6568131513452441 45 P51809,P02786,Q9NUQ9,P04439,P53634,Q08722,P30825,Q14254,P15529,Q9NPF0,P11279,Q5ZPR3 12 +Regulation of toll like receptor 3 signaling pathway 0.8500468885597903 1.3869990688585871 0.1654420467657482 1.0 0.6569948437861421 3 O75955 1 +Protein localization to membrane raft 0.8500468885597903 1.3869990688585871 0.1654420467657482 1.0 0.6569948437861421 3 O75955 1 +Regulation of heterotypic cell cell adhesion 0.8500468885597903 1.3869990688585871 0.1654420467657482 1.0 0.6569948437861421 3 O75955 1 +Regulation of synaptic vesicle recycling 0.6984908136482959 1.3857051863751426 0.1658369438778293 1.0 0.6581590122366122 5 Q9Y263,Q7L576,Q96CW1,P0DP25 4 +Negative regulation of autophagy 0.4767200297462008 1.3830798407964988 0.1666403862086274 1.0 0.6592262896728416 24 Q9NNW5,O15118,P09601,Q07820,P10619,P42345,Q86UE8 7 +Negative regulation of lipid transport 0.746705129090572 1.3827924253261872 0.166728522226351 1.0 0.6592262896728416 4 P06756 1 +Mammary gland epithelium development 0.5873922960591952 1.3820586524300031 0.1669536927633927 1.0 0.6592262896728416 9 Q9NQC3 1 +Cellular response to arsenic containing substance 0.609142829929714 1.380669345890214 0.1673806506920776 1.0 0.6592262896728416 8 P09601 1 +Regulation of systemic arterial blood pressure mediated by a chemical signal 0.7460858920250681 1.380189451761931 0.1675283209065661 1.0 0.6592262896728416 4 P42892 1 +Entry of bacterium into host cell 0.6971162390232352 1.379520940571569 0.1677341943481822 1.0 0.6592262896728416 5 Q9BTY2 1 +Fc receptor mediated stimulatory signaling pathway 0.6310048292781996 1.3793928614424305 0.1677736590341705 1.0 0.6592262896728416 7 Q06481 1 +Maintenance of protein localization in organelle 0.5096094363337891 1.374951704353852 0.1691464180348658 1.0 0.6615375769520544 16 O15258,P52789,O43731,P24390,O43292 5 +Positive regulation of immune system process 0.3789743719539902 1.374189671130976 0.1693828065106124 1.0 0.6615375769520544 114 P09601,Q08722,Q9NUD5,Q96J02,P05067,Q5ZPR3,P02786,O15400,P53634,Q07021,Q14254,P01889,Q9NUQ9,Q99538,Q06481,P30825,Q9NPF0,P51809,P04439,Q7KYR7,P15529,Q4KMQ2,P11279 23 +Organic hydroxy compound transport 0.4759878220045288 1.3731383474371934 0.1697093416583406 1.0 0.6615375769520544 29 O15118,P61916,Q8WTV0,Q07954,P04114,Q14849,Q86Y82,Q9H2C2,P01130 9 +Cellular response to nutrient 0.6479306929294769 1.3724456353598928 0.169924751871662 1.0 0.6615375769520544 6 P20020,P09601 2 +Biological process involved in interaction with host 0.4313492294158058 1.3721568654526743 0.1700146101273216 1.0 0.6615375769520544 61 O43633,P05556,Q96J02,P07858,P07237,O14786,O15118,P02786,P01130,Q9H9H4,P06756,P08195,P00533,Q9BTY2,Q14108,Q16531,Q92692,Q9Y624,P35613,Q15758,Q8WTV0,P15529,P11279,P51149 24 +Alpha beta t cell proliferation 0.908226810881686 1.37190158570611 0.170094076706138 1.0 0.6615375769520544 2 P04439 1 +Regulation of chemotaxis 0.4757119574307449 1.3709231543748686 0.1703989125286811 1.0 0.6615375769520544 27 Q9NUQ9,Q99538,O94813,Q4KMQ2,Q13277,O14786,Q13641 7 +Cellular response to calcium ion 0.5852060640362619 1.370306922897779 0.1705911129207882 1.0 0.6615375769520544 9 Q99538,Q92542 2 +Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules 0.7435924009613168 1.3697058140611849 0.1707787530545572 1.0 0.6615375769520544 4 P19022,Q9P273 2 +Calcium ion export across plasma membrane 0.8449467851304873 1.3666514544106707 0.171734580921453 1.0 0.6629458505457605 3 P0DP25 1 +Positive regulation of exocytosis 0.5082470240379633 1.3659261364386 0.1719621482788353 1.0 0.6629458505457605 16 P20339,P51809,Q8WUM4,O00560,P11279,P51149,P51151 7 +Semaphorin plexin signaling pathway 0.6281469901468533 1.3651587234929736 0.1722031684557659 1.0 0.6634796287911551 7 O15031,P42892 2 +Autophagy of mitochondrion 0.4748143431512333 1.364020738419972 0.1725610387537735 1.0 0.6639779647317412 29 P52789,P04062,Q13501,P12235,Q9Y4P8,P05141,Q9BWH2,P49815,P21796,P27544 10 +Calcium ion transport 0.451320245819395 1.3635036722324017 0.1727238279142138 1.0 0.6639779647317412 52 Q9HC07,O75844,P06756,P17612,P08195,P62942,P16615,O76024,Q8IYU8,P04899,Q4KMQ2,P21796,Q9BPX6,O95202,P0DP25,P20020 16 +Positive regulation of monocyte chemotaxis 0.8436689144560369 1.361553087307288 0.1733389689441407 1.0 0.6639779647317412 3 Q99538 1 +Microglia differentiation 0.9056047197640232 1.3610599577773157 0.1734947424099553 1.0 0.6639779647317412 2 P05067 1 +Cerebellar purkinje cell layer formation 0.9056047197640112 1.3610599577772655 0.1734947424099711 1.0 0.6639779647317412 2 Q04656 1 +Cerebellar purkinje cell layer morphogenesis 0.9056047197640112 1.3610599577772655 0.1734947424099711 1.0 0.6639779647317412 2 Q04656 1 +Cellular potassium ion homeostasis 0.843278688524587 1.359996189312617 0.1738311297877195 1.0 0.6639779647317412 3 P05023,P55011 2 +Adaptive immune response 0.4636579178592674 1.35758359052792 0.1745958527669038 1.0 0.6639779647317412 44 P02786,P10321,Q9NUQ9,P04439,O15400,P53634,Q03518,Q96FW1,P15529,Q9NZ08 10 +Hindbrain morphogenesis 0.6046485069313257 1.3574181534401082 0.1746483833391221 1.0 0.6639779647317412 8 Q04656 1 +Protein localization to endosome 0.5371003888196363 1.3572660630359776 0.1746966864012542 1.0 0.6639779647317412 13 Q9NV96,Q92673 2 +Endocrine process 0.7402819485291074 1.355782152263974 0.1751684916030598 1.0 0.6639779647317412 4 P42892 1 +Regulation of nik nf kappab signaling 0.4952793804585544 1.3556629637177262 0.1752064284738108 1.0 0.6639779647317412 17 O43657,P05067 2 +Regulation of the force of heart contraction 0.7387826776913465 1.3494744340147444 0.1771846267304679 1.0 0.6691227964503196 4 P16615,P10253 2 +Positive regulation of mitochondrial translation 0.6902818075464717 1.3487470228496574 0.1774182361721727 1.0 0.6696141013989415 5 Q567V2,Q9Y2R0 2 +Phosphatidylethanolamine biosynthetic process 0.9023271058669284 1.3475132722507304 0.1778149817954997 1.0 0.669854465123806 2 P35790 1 +Glial cell development 0.4719183229833379 1.346805564714909 0.1780428620606831 1.0 0.669854465123806 24 Q92542,Q07954,P15260,P01130,P05067 5 +Hyperosmotic response 0.6024893874533596 1.346235470220532 0.1782265892578025 1.0 0.669854465123806 8 O95202,P11166,P55011 3 +Azole transmembrane transport 0.9019993444772304 1.3461589512609942 0.1782512601409829 1.0 0.669854465123806 2 P30825 1 +Osteoblast proliferation 0.6423638612569488 1.345549820579541 0.178447743840588 1.0 0.669854465123806 6 P06756,Q9Y251 2 +Regulation of osteoblast proliferation 0.6423638612569488 1.345549820579541 0.178447743840588 1.0 0.669854465123806 6 P06756,Q9Y251 2 +Inorganic ion import across plasma membrane 0.6240421017738037 1.344691542989472 0.1787248668338472 1.0 0.6702441527815408 7 Q15043,P05023,P55011,Q92581 4 +Extracellular vesicle biogenesis 0.5571650342627148 1.3354518388164192 0.1817285080126387 1.0 0.6756331714561838 10 O43633,Q8WUM4,Q99816,O00560,Q9Y3E7,P51149 6 +Bone mineralization 0.5569038619285251 1.3339864838426172 0.1822082862024314 1.0 0.6759566980102417 10 O75844,Q14596,Q4KMQ2 3 +Glycosyl compound catabolic process 0.556890153919974 1.3339095684207731 0.1822334953361974 1.0 0.6759566980102417 10 P08236,Q9BTY2,P04066,P06280 4 +Positive regulation of anion transport 0.6398083824477425 1.3331897555256862 0.1824695403737695 1.0 0.6764443877810401 6 P55011,Q15042 2 +Regulation of synapse structure or activity 0.4702924236017822 1.330976172187693 0.1831968513912454 1.0 0.6778200188879029 31 Q15375,P19022,Q12834,P50897,O00264,P05067,Q13641 7 +Synaptic vesicle recycling 0.5133715493658639 1.3295514405343567 0.183666106506682 1.0 0.6778200188879029 15 Q7L576,P20339,P27824,P14672,Q9Y263,P0DP25,Q00535,Q96CW1 8 +Negative regulation of protein maturation 0.685939685856166 1.3291747048968037 0.1837903383193277 1.0 0.6778200188879029 5 Q9BXS4 1 +Positive regulation of neutrophil migration 0.7338390375121197 1.328668221749332 0.1839574535499708 1.0 0.6778200188879029 4 Q07021 1 +Positive regulation of granulocyte chemotaxis 0.7338390375121197 1.328668221749332 0.1839574535499708 1.0 0.6778200188879029 4 Q07021 1 +Response to corticosterone 0.8354098360655738 1.328603016627227 0.1839789762968222 1.0 0.6778200188879029 3 P20020,P0DP25 2 +Mast cell activation involved in immune response 0.6387582419813145 1.3281081933916343 0.1841423671082864 1.0 0.6779834791255009 6 P09601 1 +Epithelial cell differentiation involved in prostate gland development 0.8348620953668332 1.3264179757718522 0.1847012878397373 1.0 0.6786750196990551 3 P07602 1 +Triglyceride biosynthetic process 0.7332696871610425 1.326271331705604 0.184749839185351 1.0 0.6786750196990551 4 P01130 1 +Astrocyte differentiation 0.5225625387535675 1.3249873565962678 0.1851753448322561 1.0 0.6798520463790382 14 Q07954,P05067,P15260 3 +Protein targeting to membrane 0.4694915279426995 1.324659025449903 0.185284269127151 1.0 0.679866101522144 31 Q9H9H4,P40855,P43307,O00560,O60725,Q15629,P31751 7 +Response to endoplasmic reticulum stress 0.3741214239629304 1.3228982383934829 0.1858692212429837 1.0 0.6809966147950529 77 P27824,P16615,O75955,Q8TCT9,O95831,P33908,O76024,Q15363,P07237,O60313,Q9H3N1,O95881,Q9Y4P3,Q9BUN8,Q4ZIN3,Q96HY6,Q96A33 17 +Foam cell differentiation 0.7322892470901262 1.3221435048309207 0.1861203693233788 1.0 0.681388041399512 4 P04114,P06756 2 +Positive regulation of monooxygenase activity 0.6191210801693711 1.320122606357553 0.1867940862140853 1.0 0.6817354483898295 7 P16435,Q04656,Q8WTV0,P0DP25 4 +Vacuolar proton transporting v type atpase complex assembly 0.8954441166830547 1.319087120535603 0.1871399884470412 1.0 0.6817354483898295 2 Q8N511 1 +Regulation of necrotic cell death 0.5540636648411441 1.3180414442874564 0.1874897745663821 1.0 0.6817354483898295 10 P12235,Q13510 2 +Protein kinase b signaling 0.4686782054204512 1.3169197154027998 0.1878655371689732 1.0 0.6817354483898295 30 Q86UE4,P98164,P05556,Q07021,P42345,P00533,P08069,Q9NQC3,Q13641,Q9Y251 10 +Negative regulation of cell killing 0.8323667701984685 1.3164641747221562 0.1880182951487086 1.0 0.6817354483898295 3 P04439 1 +Protein maturation by protein folding 0.6826787955822746 1.314466403644029 0.1886892968567166 1.0 0.6817354483898295 5 O76024 1 +Response to nerve growth factor 0.538441389539716 1.3139701568985531 0.1888562473104993 1.0 0.6817354483898295 12 P05067,Q99523 2 +Positive regulation of transforming growth factor beta production 0.894133071124221 1.3136763374094906 0.188955147235825 1.0 0.6817354483898295 2 P15529 1 +Exocytosis 0.4051282379367216 1.3124120448202037 0.1893811450428624 1.0 0.6817354483898295 68 O43633,P20339,Q9UPT5,P09601,Q9BRK5,Q5SQN1,P54920,Q13277,P51151,O00186,O00560,P0DP25,Q15042,Q7Z6M1,O15126,P16615,Q7L0J3,P04899,P49755,P51809,O43760,Q8WUM4,P11279,P51149,P11233,Q4J6C6 26 +Detection of other organism 0.8938053097345231 1.3123238413892118 0.1894108911925376 1.0 0.6817354483898295 2 P04439 1 +Negative regulation of natural killer cell mediated immunity 0.8938053097345231 1.3123238413892118 0.1894108911925376 1.0 0.6817354483898295 2 P04439 1 +Protection from natural killer cell mediated cytotoxicity 0.8938053097345231 1.3123238413892118 0.1894108911925376 1.0 0.6817354483898295 2 P04439 1 +T cell tolerance induction 0.8938053097345134 1.3123238413891722 0.1894108911925509 1.0 0.6817354483898295 2 Q96J02 1 +Lymphocyte anergy 0.8938053097345134 1.3123238413891722 0.1894108911925509 1.0 0.6817354483898295 2 Q96J02 1 +Positive regulation of leukocyte degranulation 0.8312965033781969 1.3121952022399743 0.1894542802515766 1.0 0.6817354483898295 3 P11279 1 +Natural killer cell activation involved in immune response 0.8312965033781969 1.3121952022399743 0.1894542802515766 1.0 0.6817354483898295 3 P11279 1 +Natural killer cell degranulation 0.8312965033781969 1.3121952022399743 0.1894542802515766 1.0 0.6817354483898295 3 P11279 1 +Calcium ion regulated exocytosis of neurotransmitter 0.8934775483448076 1.3109714265556538 0.1898674173431884 1.0 0.6819835218173715 2 P16615 1 +Aromatic amino acid transport 0.8928220255653994 1.3082668430262914 0.1907828171730528 1.0 0.6835964259634694 2 P30825 1 +Alanine transport 0.8928220255653883 1.3082668430262463 0.1907828171730681 1.0 0.6835964259634694 2 Q96QD8 1 +Modified amino acid transport 0.6809766588585764 1.3067857927391775 0.1912854716174592 1.0 0.68363529293452 5 P98164,Q9H2D1 2 +Regulation of mitochondrial membrane permeability 0.5195546836173414 1.3061847325070688 0.1914897435148168 1.0 0.68363529293452 14 P52789,P12235,P45880 3 +Positive regulation of amine transport 0.8291803278688483 1.3037550385611911 0.192317116993236 1.0 0.6839469102965196 3 P55011,Q15042 2 +Positive regulation of amino acid transport 0.8291803278688483 1.3037550385611911 0.192317116993236 1.0 0.6839469102965196 3 P55011,Q15042 2 +Neuroinflammatory response 0.8291803278688393 1.3037550385611547 0.1923171169932485 1.0 0.6839469102965196 3 P53634,P01130 2 +Cellular response to low density lipoprotein particle stimulus 0.8291803278688394 1.3037550385611547 0.1923171169932485 1.0 0.6839469102965196 3 P01130,O15118 2 +Regulation of spontaneous synaptic transmission 0.8291803278688344 1.3037550385611345 0.1923171169932553 1.0 0.6839469102965196 3 P05067,P55011 2 +Spontaneous synaptic transmission 0.8291803278688344 1.3037550385611345 0.1923171169932553 1.0 0.6839469102965196 3 P05067,P55011 2 +Regulation of endoplasmic reticulum unfolded protein response 0.5727040987347146 1.3029236182699844 0.1926008397059637 1.0 0.6843963707585757 9 O76024,Q96HY6 2 +Astrocyte development 0.5940432468884009 1.3024161413789592 0.1927741676485372 1.0 0.6844188409928281 8 Q07954,P05067,P15260 3 +Amyloid beta clearance by cellular catabolic process 0.8285145332204329 1.301099769406049 0.193224306699163 1.0 0.6844188409928281 3 Q07954 1 +Regulation of postsynaptic membrane neurotransmitter receptor levels 0.5937367689431317 1.300823968640647 0.1933187157076783 1.0 0.6844188409928281 8 Q14254,Q13277,Q92796 3 +Negative regulation of cellular response to growth factor stimulus 0.5509853762080148 1.300740294712524 0.1933473647211143 1.0 0.6844188409928281 10 O94813,P98164,Q92673 3 +Protein o linked glycosylation via threonine 0.8908554572271454 1.3001551082166052 0.1935478131774299 1.0 0.6844188409928281 2 Q10472 1 +Er overload response 0.7270092777383085 1.2999078554539074 0.1936325524250417 1.0 0.6844188409928281 4 Q96A33 1 +Regulation of receptor signaling pathway via stat 0.6150675140659709 1.2998593366279898 0.1936491841473082 1.0 0.6844188409928281 7 Q9H490 1 +Vesicle localization 0.4267477233627779 1.2996226769715755 0.1937303235232588 1.0 0.6844188409928281 60 O43633,P49755,Q92572,P19022,Q8WUM4,O00560,Q96A57,P14672,O95772,Q14849,Q15363,P62820,O00743,Q9HCU5,Q9Y6B6,Q13561,P51149,Q9NR31 18 +Embryonic heart tube development 0.6327797154381858 1.2991534716675264 0.1938912655778768 1.0 0.6844188409928281 6 P42892 1 +Organic acid transport 0.4580081084090986 1.2983295639015702 0.1941741115526971 1.0 0.6844188409928281 43 Q96QD8,P55011,P05556,O75915,O60831,O43808,Q9Y619,Q6P4A7,P98164,Q15042,P08195,O14678,P30825,Q7L0J3,P23786,Q9H2D1,Q15758,Q9UBX3,P11166,P31751 20 +Positive regulation of immune effector process 0.4631590008011508 1.2952143617785736 0.1952462918092656 1.0 0.6854718105198502 37 P01889,P02786,P09601,Q9NUQ9,P04439,O15400,Q06481,P15529,P11279 9 +Odontogenesis of dentin containing tooth 0.5926428368040291 1.2951397480208289 0.1952720252606576 1.0 0.6854718105198502 8 P35613 1 +Secondary metabolic process 0.5926287844787704 1.2950667183791669 0.1952972147763521 1.0 0.6854718105198502 8 P19021 1 +Membrane repolarization 0.6138074598149698 1.293556044336616 0.1958188137023779 1.0 0.6854718105198502 7 O75844,Q96PU5,P05023 3 +Neurotransmitter secretion 0.4615333371593921 1.2902833957767252 0.1969522797972371 1.0 0.6873843796300634 19 P20339,Q15042,P16615,Q7L0J3,Q5SQN1,P50897,P54920,Q13277,P0DP25,Q4J6C6 10 +Sterol homeostasis 0.5169906142941497 1.2901380614115414 0.1970027268254965 1.0 0.6873843796300634 14 O15118,P61916,Q8WTV0,P04114,Q9H4M9,P01130 6 +Cardiac chamber development 0.4619775554969039 1.288019391268987 0.1977392131513617 1.0 0.6878257434936932 20 O75844,P98164,P16870,P62942,P08069,Q13308,O94813,O14786 8 +Oligodendrocyte progenitor proliferation 0.8251419435811929 1.2876510783185815 0.1978674503727227 1.0 0.6878257434936932 3 P98164 1 +Regulation of granulocyte chemotaxis 0.569863314309927 1.2875717866902794 0.1978950656625913 1.0 0.6878257434936932 9 Q07021,O94813 2 +Lymphocyte migration 0.5484672231788371 1.2865727099835145 0.1982432606904551 1.0 0.6878257434936932 10 Q9Y624,P04062,P05067 3 +Negative regulation of synapse organization 0.887250081940361 1.2852918361839234 0.1986903219210809 1.0 0.6878257434936932 2 Q15375 1 +Presynaptic endocytosis 0.5480230312119726 1.2840722715318376 0.1991166690748689 1.0 0.6878257434936932 10 P27824,P14672,P0DP25 3 +Regulation of cellular response to osmotic stress 0.8240043647307231 1.283115488884714 0.1994516180791019 1.0 0.6878257434936932 3 O95202 1 +Positive regulation of b cell proliferation 0.7228599540832839 1.2824275982993478 0.1996926880039358 1.0 0.6878257434936932 4 Q9NPF0,P02786,Q96QE3 3 +Vasoconstriction 0.6755163844790466 1.282133992235713 0.1997956464612627 1.0 0.6878257434936932 5 P42892 1 +Negative regulation of amyloid beta clearance 0.8236975829156508 1.2818923964302382 0.1998803956215555 1.0 0.6878257434936932 3 P15260 1 +Negative regulation of neuron apoptotic process 0.4635340004793481 1.280607583147769 0.2003315351216927 1.0 0.6878257434936932 25 P04062,P09601,Q99538,O76024,P50897,Q01105,P07196,O14786 8 +Terpenoid metabolic process 0.4724477895633606 1.2792880927347692 0.2007956241244033 1.0 0.6878257434936932 18 Q07954,P98164,Q9HB40,P51648 4 +Gliogenesis 0.43183078985814 1.2787508906383342 0.2009847925184382 1.0 0.6878257434936932 57 P04062,Q96N66,P98164,Q96G23,Q92542,Q9NQC3,P07686,Q07954,P15260,P07942,P01130,P05067,P31751 13 +Detection of biotic stimulus 0.7218103828590952 1.2780052629373622 0.2012475705853045 1.0 0.6878257434936932 4 P04439,P01889 2 +Prostate gland growth 0.8852835136021124 1.2771893529919742 0.2015354049557447 1.0 0.6879294727587333 2 P07602 1 +Dendritic cell chemotaxis 0.721071915039875 1.2748936022623405 0.2023469038653926 1.0 0.6900274755430813 4 Q4KMQ2 1 +Cellular response to dsrna 0.5461684669368347 1.2736283452919297 0.2027951617461569 1.0 0.6907213004137843 10 Q5KU26,Q9NUD5 2 +Response to mineralocorticoid 0.5884773324812558 1.2734788633096985 0.2028481682765961 1.0 0.6907213004137843 8 O95831,P07196,P20020,P0DP25 4 +Hindbrain development 0.4624250824345383 1.2728313259467263 0.2030779025265832 1.0 0.6908714021922815 33 P54802,O14949,Q04656,Q92542,Q9BRK5,Q5KU26 6 +Cellular response to insulin like growth factor stimulus 0.7202581240714356 1.271464420249706 0.2035634773727788 1.0 0.6908714021922815 4 P08069,Q9BSK2 2 +Regulation of cardiac conduction 0.820655737704918 1.269766602153731 0.2041677805767061 1.0 0.6908714021922815 3 P16615,P20020 2 +Extracellular exosome assembly 0.7195801902262849 1.268607616533971 0.2045810464546495 1.0 0.6908714021922815 4 Q8WUM4,Q99816,O00560 3 +High density lipoprotein particle clearance 0.8829891838741475 1.2677409461867175 0.2048904772125384 1.0 0.6908714021922815 2 P01130 1 +Positive regulation of triglyceride metabolic process 0.8829891838741475 1.2677409461867175 0.2048904772125384 1.0 0.6908714021922815 2 P01130 1 +Regulation of triglyceride biosynthetic process 0.8829891838741475 1.2677409461867175 0.2048904772125384 1.0 0.6908714021922815 2 P01130 1 +Positive regulation of triglyceride biosynthetic process 0.8829891838741475 1.2677409461867175 0.2048904772125384 1.0 0.6908714021922815 2 P01130 1 +Calcium ion transmembrane transport 0.4589807410332028 1.2665200621339825 0.2053269514428186 1.0 0.6908714021922815 38 Q9HC07,P06756,Q9BPX6,P62942,P16615,Q8IYU8,Q4KMQ2,P0DP25,P21796,O95202,P20020 11 +Regulation of neurotransmitter uptake 0.8191509011908249 1.2637689791470523 0.2063129584233904 1.0 0.6908714021922815 3 O75955 1 +Ovulation cycle process 0.6254480666295319 1.2635914469642442 0.2063767050783718 1.0 0.6908714021922815 6 O94813,P19021 2 +Regulation of coagulation 0.67084308329855 1.2610207712048915 0.2073013636327307 1.0 0.6912538769794512 5 Q9UNN8,Q9Y251 2 +Positive regulation of small gtpase mediated signal transduction 0.6070697774586981 1.259817810394344 0.207735093288722 1.0 0.6912677066377387 7 Q9Y624,P06756,Q15555 3 +Copi coated vesicle budding 0.7174173546927569 1.259492903815571 0.2078523517456065 1.0 0.6912677066377387 4 Q15363 1 +Negative regulation of defense response to virus 0.6245273239975666 1.2591215332662138 0.2079864377831151 1.0 0.6912677066377387 6 Q96J02,O43657 2 +N glycan processing 0.71715405988049 1.2583832636223309 0.2082531816743795 1.0 0.6912677066377387 4 P33908,Q16706 2 +Tetrapyrrole catabolic process 0.7167407915612777 1.2566415485066291 0.208883462579112 1.0 0.6912677066377387 4 P09601 1 +Regulation of hormone biosynthetic process 0.8170491803278631 1.2553938446575912 0.2093358227397326 1.0 0.6912677066377387 3 P05023,P16435 2 +Regulation of steroid hormone biosynthetic process 0.8170491803278631 1.2553938446575912 0.2093358227397326 1.0 0.6912677066377387 3 P05023,P16435 2 +Immune effector process 0.3833062414092227 1.2546613490941665 0.2096017223439721 1.0 0.6917103409227698 73 P02786,P09601,P01889,Q9NUQ9,P04439,O15400,P53634,Q08722,Q06481,Q04656,Q07954,P15529,P11279,P05067 14 +Positive regulation of epithelial cell apoptotic process 0.8166754815517192 1.253904876808512 0.2098765822389148 1.0 0.6917103409227698 3 Q4KMQ2 1 +Chemosensory behavior 0.8793838085873564 1.25290376890718 0.2102407301156721 1.0 0.6918020777661665 2 Q13641 1 +Olfactory behavior 0.8793838085873564 1.25290376890718 0.2102407301156721 1.0 0.6918020777661665 2 Q13641 1 +Regulation of phospholipase a2 activity 0.6690262256113955 1.252809327022456 0.2102751064561703 1.0 0.6918020777661665 5 Q07954,P50897 2 +Humoral immune response mediated by circulating immunoglobulin 0.8156914792213077 1.2499844872338588 0.2113052141737479 1.0 0.6931711107961336 3 P15529 1 +Positive regulation of axonogenesis 0.4906647559728744 1.2489522565160909 0.211682536783722 1.0 0.6934888259348047 16 O15031,O94813,O14786 3 +Neurotransmitter transport 0.4592513224007385 1.2478605328848835 0.2120821361461411 1.0 0.6937584278463489 25 P20339,Q96QD8,Q15042,O00186,P16615,P05556,O75955,Q7L0J3,Q5SQN1,P50897,P54920,Q13277,P0DP25,Q4J6C6 14 +Sulfate transport 0.8144503648647408 1.2450403208842096 0.2131169293018198 1.0 0.6945157977013071 3 Q9UBX3 1 +Positive regulation of reproductive process 0.6040871196888926 1.2448654080359984 0.2131812282112433 1.0 0.6945157977013071 7 P36896 1 +Placenta development 0.4574515654333244 1.244519832016945 0.213308304986848 1.0 0.6945157977013071 22 P07858,P35613,P00533 3 +Glutamate receptor signaling pathway 0.8142780476095475 1.2443539227642235 0.213369333308488 1.0 0.6945157977013071 3 P05067 1 +Regulation of protein localization to membrane 0.4527942884655892 1.2441811594033554 0.2134328962482916 1.0 0.6945157977013071 42 P19022,Q13501,O15400,P00533,Q07954,Q9BXS4,O00264,Q13277,P31751,Q9UNK0 10 +Homologous chromosome segregation 0.5340232323547359 1.243484369063521 0.2136893974238214 1.0 0.695000860701207 11 Q92791,Q9BTX1,Q9BXW9 3 +Cardiac septum development 0.5263982567466547 1.2426168463832514 0.214009059016599 1.0 0.6952525837999631 12 O14786,Q13308,O94813,P98164 4 +Regulation of autophagy of mitochondrion 0.50935377221077 1.242250291605005 0.2141442293939313 1.0 0.6952525837999631 14 P12235,P05141,P49815,P21796,P27544 5 +Positive regulation of endocytic recycling 0.8767617174696966 1.2421214818963806 0.2141917437523308 1.0 0.6952525837999631 2 Q92673 1 +Regulation of immune response 0.372222327377258 1.24160584494388 0.2143820241785516 1.0 0.6952525837999631 118 P09601,Q08722,Q9NUD5,Q96J02,Q5ZPR3,P02786,O15400,Q9NZ08,O43657,Q9NQC3,O00115,P01889,Q9NUQ9,Q06481,P51809,P04439,O75955,P15529,Q5KU26,P11279,Q8TCT8 21 +Acute inflammatory response 0.6665435985315846 1.2415863000458045 0.2143892390366766 1.0 0.6952525837999631 5 P02786,Q9BQE5 2 +Negative regulation of axon extension 0.8130030088697249 1.239275431337742 0.2152435140724229 1.0 0.6956522278016355 3 Q9NQC3 1 +Neuron death 0.3746822435978035 1.237242841511528 0.2159969409201698 1.0 0.6968998557668722 75 Q15392,P09601,Q96A26,O75915,Q4ZIN3,O14786,P05067,P04062,Q15375,Q99720,O95831,Q01105,Q92673,P50897,Q9NR28,Q99538,Q92542,O76024,P07196,P31751 20 +Aorta development 0.5812040912047555 1.235599105509742 0.2166076173687634 1.0 0.6978260342422962 8 Q07954 1 +Response to metal ion 0.4200568211029684 1.2323129128558066 0.2178322180456855 1.0 0.7003760529510635 60 P35613,O15118,P02786,P09601,Q99538,Q04656,Q6NUK1,O60888,P00533,Q92542,P19021,P0DP25,P05067,Q96PU5 14 +Regulation of epithelial cell apoptotic process 0.5591142750245323 1.2293608124048323 0.2189365560644502 1.0 0.7025300501889528 9 Q53EL6,O76024,Q4KMQ2,P09601 4 +Regulation of vasoconstriction 0.8097479441949667 1.2263140373041646 0.220080520906416 1.0 0.703485072199725 3 P42892 1 +Sodium ion import across plasma membrane 0.8728285807931897 1.225962191487296 0.2202129032623845 1.0 0.703485072199725 2 Q92581 1 +Transepithelial chloride transport 0.8728285807931819 1.225962191487264 0.2202129032623965 1.0 0.703485072199725 2 P51798 1 +Regulation of exosomal secretion 0.5584149159802304 1.225567205991522 0.2203615850170452 1.0 0.7035831230622145 9 O43633,Q8WUM4,Q99816,O00560,Q9Y3E7,P51149 6 +Regulation of secretion 0.3661216271090931 1.2235238466516225 0.2211319029495155 1.0 0.704184345049733 77 P20339,P55011,P09601,P51151,Q9H4A5,O00560,Q16850,P0DP25,P19021,Q15042,P16615,Q7L0J3,P04899,Q96KC8,P49755,P51809,Q8WUM4,O00429,Q32P28,P11279,P51149,P11233,Q4J6C6 23 +Embryonic axis specification 0.6171666575167198 1.223359921244901 0.2211937840687985 1.0 0.704184345049733 6 Q9Y2W6 1 +Regulation of peptidase activity 0.3432729793469165 1.2179404313430862 0.2232466103502186 1.0 0.7075856552452544 85 Q15392,P61289,Q96A26,O75915,Q9P0J0,P07858,P05067,Q15375,O95831,Q92673,Q9NR28,Q9BXK5,Q99538,Q06481,Q92542,Q96HY6,Q9NZJ7,Q07954,P78318,P16435 20 +Mitochondrial electron transport ubiquinol to cytochrome c 0.7070249312317705 1.2156898682848984 0.2241030851597192 1.0 0.7098359106143053 4 O14949 1 +Cell morphogenesis involved in differentiation 0.3694941631505655 1.2154984640954685 0.2241760342224494 1.0 0.7098359106143053 117 P62820,P07237,O14786,P05067,Q96PU5,Q15375,P19022,P98155,P07942,Q9NQC3,Q13641,P06756,Q06481,O94813,Q92581,O00264,O15031,P35613,P42892,O75955 20 +Regulation of ossification 0.5289262399298288 1.2139746386500854 0.224757408904868 1.0 0.7099028220256285 11 O75844,Q14596,Q4KMQ2 3 +Bicarbonate transport 0.8698787282858071 1.213854535779189 0.2248032766875438 1.0 0.7099028220256285 2 P04920 1 +Positive regulation of mitochondrial membrane potential 0.6604031886057871 1.2138167600168552 0.2248177047897399 1.0 0.7099028220256285 5 P31751 1 +Cell junction maintenance 0.5561096190269954 1.213057323042957 0.2251079050585511 1.0 0.7103527013774474 9 Q9BRK5 1 +Regulation of receptor binding 0.7057731630671186 1.2104136178975762 0.226120219014513 1.0 0.7108147291372452 4 P16615,P10586 2 +Regulation of adaptive immune response 0.4524993176635435 1.2071709038249223 0.2273663333028521 1.0 0.7124164271464001 22 P02786,Q9NUQ9,P04439,O15400,P15529 5 +Regulation of systemic arterial blood pressure 0.5965633960903399 1.2071064111466414 0.2273911661803453 1.0 0.7124164271464001 7 O75787,P42892 2 +Regulation of notch signaling pathway 0.6135887502417998 1.205960444898235 0.2278327424079127 1.0 0.7124164271464001 6 P15529 1 +Serine transport 0.7046210950530525 1.205557682965217 0.2279880840510721 1.0 0.7124164271464001 4 Q96QD8,Q15758 2 +Nephron development 0.4620050355624404 1.2045893118207536 0.2283618848474304 1.0 0.7124164271464001 18 O00592,P14543 2 +Learning 0.4495818251026328 1.201586708349791 0.2295236937292262 1.0 0.7124492185815696 19 Q99538,P50897,P05067,Q13641 4 +Zinc ion transport 0.8666011143887418 1.2004142039708166 0.2299785151499094 1.0 0.7124492185815696 2 Q8NEW0 1 +Retinol metabolic process 0.6121228447101313 1.198828951416706 0.2305944626558349 1.0 0.7124492185815696 6 Q9Y394,Q6NUM9,Q8NBN7,Q8TC12 4 +Regulation of chondrocyte differentiation 0.7027251006893169 1.1975663549960822 0.2310858808080622 1.0 0.7124492185815696 4 Q92896 1 +Response to interleukin 12 0.8656178302196122 1.1963848052815476 0.2315464281132007 1.0 0.7124492185815696 2 Q08722 1 +Establishment of endothelial intestinal barrier 0.5736683058791803 1.1962815546465442 0.2315867043440926 1.0 0.7124492185815696 8 Q9Y624,P62820 2 +Axonogenesis involved in innervation 0.8652900688299057 1.1950419567158188 0.232070637850811 1.0 0.7124492185815696 2 P42892 1 +Innervation 0.8652900688299057 1.1950419567158188 0.232070637850811 1.0 0.7124492185815696 2 P42892 1 +Outflow tract septum morphogenesis 0.8652900688299017 1.1950419567158028 0.2320706378508172 1.0 0.7124492185815696 2 P98164 1 +Regulation of retinal ganglion cell axon guidance 0.8652900688299006 1.1950419567157984 0.232070637850819 1.0 0.7124492185815696 2 O94813 1 +Regulation of cellular respiration 0.4606395367855077 1.1947992254306246 0.2321654830469472 1.0 0.7124492185815696 18 P14406,Q9NZ45,Q9BSK2 3 +Cardiac ventricle development 0.4919312562427709 1.1909595918803804 0.2336694484136399 1.0 0.7140329058988363 15 O75844,P98164,P16870 3 +Positive regulation of tor signaling 0.5932725238626331 1.1905737060012105 0.2338209790340988 1.0 0.7140749826552261 7 Q9HB90,Q6IAA8 2 +Regulation of cell size 0.449784396343527 1.1900292201254452 0.234034907538631 1.0 0.7141376494657565 38 Q15375,P54105,P55011,Q04656,P51790,Q4KMQ2,Q9NQC3 7 +Response to peptide 0.3537501844956238 1.1879390491475976 0.2348574237856395 1.0 0.7156347972064542 100 Q15043,O14654,P08670,P05067,Q92572,P56192,O00186,P42345,P14672,P08069,Q92673,P20020,Q9UQB8,Q99538,Q06481,Q99523,P09960,P04899,P49815,Q9BSK2,P35613,Q07954,P11166,P16435,Q96A49,P07196,P31751,P43490 28 +Cranial nerve development 0.7000999945173881 1.1865026321893235 0.2354238626115934 1.0 0.715651878397594 4 Q9H061 1 +Natural killer cell mediated immunity 0.530638609428043 1.1859240022906536 0.2356523133731087 1.0 0.715651878397594 10 P51809,P01889,P11279,P04439 4 +Regulation of protein localization to cell periphery 0.4516000144767806 1.1858155377223618 0.2356951540759644 1.0 0.715651878397594 33 O15258,Q13501,O15400,P00533,Q07954,Q9BXS4,O00264,Q13277,Q9UNK0 9 +Lung alveolus development 0.79934970215354 1.1849496203187215 0.2360373667021409 1.0 0.7158582865429675 3 Q04656 1 +Negative regulation of endoplasmic reticulum unfolded protein response 0.6091574708740716 1.1843981979968887 0.2362554732067683 1.0 0.7159795458263085 6 Q96HY6 1 +Glial cell proliferation 0.6537186340924475 1.183572838921127 0.2365821973903843 1.0 0.7159795458263085 5 Q96G23 1 +Growth plate cartilage development 0.7985106633455596 1.1816150121011493 0.2373584941633411 1.0 0.7164429222224252 3 O75844 1 +Bone growth 0.7985106633455596 1.1816150121011493 0.2373584941633411 1.0 0.7164429222224252 3 O75844 1 +Regulation of cell development 0.338755370869982 1.1797593480556017 0.2380959420933239 1.0 0.7167466311834026 83 Q9Y624,Q15375,O15031,Q9UQB8,P98164,Q06481,Q07021,Q96G23,P42345,P01130,O94813,Q15154,Q92673,P55209,P07196,O14786,P07237,Q9NQC3 18 +Renal filtration 0.797952809775391 1.1793982091991235 0.2382396478899053 1.0 0.7167466311834026 3 P43121 1 +Pyrimidine containing compound transmembrane transport 0.7977026423171907 1.1784041668770442 0.2386355173224621 1.0 0.7167466311834026 3 Q9BSK2 1 +Secretion 0.3804786032521446 1.17837134285606 0.2386485971399368 1.0 0.7167466311834026 135 O43633,P20339,P52789,Q9UNS2,Q9UPT5,P09601,P55011,Q9BRK5,Q5SQN1,Q86YV9,P62820,Q13505,P54920,Q13277,P51151,Q9UBV2,Q9H4A5,O00186,P27824,O00560,Q16850,P50897,P11234,P0DP25,P20645,P19021,P16870,Q15042,O15126,Q7Z6M1,P16615,Q04656,P00403,Q7L0J3,P04899,Q96KC8,Q9HCU5,P49755,P51809,Q15758,Q8WUM4,O43760,O00429,Q32P28,P11279,P51149,P11233,Q4J6C6 48 +Positive regulation of cell projection organization 0.4017209576272066 1.1783412318800917 0.2386605962997621 1.0 0.7167466311834026 65 O15031,Q9P273,Q86VR2,Q16625,Q9UQB8,P98155,Q9NV96,Q04656,Q15555,P42345,P08069,Q13308,O94813,Q14108,P07196,Q9H4M9,O14786,P11233 18 +Isoprenoid metabolic process 0.4485895183039711 1.1776317286533575 0.2389434550411897 1.0 0.7167466311834026 22 P98164,Q9HB40,Q07954,Q8NBN7,P51648 5 +Regulation of tolerance induction 0.7975050599663728 1.1776191050330729 0.2389484898599068 1.0 0.7167466311834026 3 Q96J02 1 +Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 0.7974792406298861 1.177516518202541 0.238989408480847 1.0 0.7167466311834026 3 P0DP25 1 +Collagen catabolic process 0.6977715195328953 1.1766900243816785 0.2393192509069117 1.0 0.7174032595536665 4 P07858 1 +Vesicle fusion to plasma membrane 0.7970163232574352 1.175677314649537 0.2397238471227758 1.0 0.7182832640283635 3 Q13277 1 +Positive regulation of trophoblast cell migration 0.8603736479842852 1.1749168944074155 0.2400279658712776 1.0 0.7188615329728217 2 P36896 1 +Glycosylceramide catabolic process 0.7965767323917523 1.1739309402909166 0.2404226882631477 1.0 0.7193775996180862 3 P06280 1 +Regulation of immune effector process 0.4424079288380115 1.1731031524870217 0.2407544424770231 1.0 0.7197044770720253 44 P51809,P02786,P09601,P01889,Q9NUQ9,P04439,O15400,Q07021,Q08722,Q06481,P15529,P11279 12 +Long term memory 0.6964635028072899 1.1711782954290737 0.2415271176583848 1.0 0.7208231587452127 4 P01130 1 +Negative regulation of macroautophagy 0.5138753818475197 1.1681150850114543 0.2427603462767611 1.0 0.7221370405938735 12 P42345,O15118,P09601 3 +Organelle disassembly 0.4389555859382343 1.1639184237867488 0.2444570724910697 1.0 0.724744638838098 46 P52789,P04062,Q13190,Q13501,Q86VR2,Q9Y4P8,P12235,Q9Y6I9,P05141,Q9BWH2,P49815,P21796,P27544,Q96HY6 14 +Regulation of cartilage development 0.6488819503895916 1.1616841628619288 0.2453637810431179 1.0 0.7252123748202036 5 Q92896 1 +Negative regulation of leukocyte proliferation 0.5875204126603856 1.161654876676275 0.2453756816159515 1.0 0.7252123748202036 7 P10644 1 +Regulation of cellular response to insulin stimulus 0.4554434220594658 1.157502643159403 0.2470670600382816 1.0 0.7271505056358707 18 Q06481,P04899,P20020,Q92673 4 +Glycerophospholipid catabolic process 0.586352694215712 1.1557811855260995 0.247770670655218 1.0 0.7284294312662017 7 P01130,Q8NCC3 2 +Cell surface receptor signaling pathway involved in cell cell signaling 0.3679244388672538 1.155204634464475 0.2480066373395624 1.0 0.7284294312662017 75 Q9P0T7,P20339,P50402,P19022,Q9P1Z2,O75787,Q15042,Q9UQB8,P16870,Q9BZK7,Q96K76,P00533,Q07954,Q8TAA9,P49815,Q16531,P05067,Q13641 18 +Positive regulation of protein localization 0.3673499717612479 1.1550251744632956 0.2480801175243385 1.0 0.7284294312662017 120 Q92544,Q13501,P02786,Q9H4A5,O00264,P55786,Q9NV96,P00533,Q07954,Q96D46,Q9NR31,Q92673,Q9Y6B6,Q9Y282,Q13277,Q9NQC3,P31751 17 +Magnesium ion transport 0.7917556050862719 1.154788067548046 0.248177224688624 1.0 0.7284294312662017 3 Q8N4V1 1 +Very low density lipoprotein particle assembly 0.7914974116303319 1.1537634276673416 0.2485971718533437 1.0 0.7293311132513745 3 P04114 1 +Cytoplasmic pattern recognition receptor signaling pathway 0.4952411345247525 1.1534256696222265 0.2487357103517573 1.0 0.7293380918829644 14 Q9NUD5,O43657,Q96J02 3 +Immune response regulating signaling pathway 0.4189600343196183 1.1527944457383994 0.2489947646946593 1.0 0.7293380918829644 57 Q96J02,P04439,Q06481,Q07021,Q08722,O75955,Q7KYR7,Q14254,O43657,Q5KU26,Q9NUD5,Q9NQC3,Q5ZPR3 13 +Regulation of peptidyl tyrosine phosphorylation 0.4474540495684193 1.1524252019492216 0.2491463897977819 1.0 0.7293380918829644 27 Q15375,Q9H223,P05067,P00533 4 +Cell cell adhesion mediated by cadherin 0.5856186567065468 1.1520884680041985 0.2492847214224838 1.0 0.7293380918829644 7 O75955,P19022 2 +Endoplasmic reticulum unfolded protein response 0.4442556249649477 1.1499908550979323 0.2501476378281253 1.0 0.7306493552918396 21 O76024,Q15363,Q9BUN8,Q9Y4P3,Q96HY6 5 +Er nucleus signaling pathway 0.5030895089685975 1.149922080345366 0.2501759656780684 1.0 0.7306493552918396 13 O76024,P16615,Q96A33,Q15363 4 +Regulation of long term synaptic potentiation 0.601109876207923 1.1452093452068572 0.2521224480979065 1.0 0.7337372473104459 6 Q99538,Q13501,P05067 3 +Ventricular septum development 0.5635655482634848 1.1434768379751103 0.2528406660199935 1.0 0.7347016716808327 8 P98164 1 +L serine transport 0.7888524590163979 1.1432703534423496 0.2529263599989511 1.0 0.7347016716808327 3 Q96QD8,Q15758 2 +Regulatory t cell differentiation 0.8525073746312778 1.142790798556842 0.2531254600670833 1.0 0.7349500005269131 2 P15529 1 +Leukocyte cell cell adhesion 0.4426723874484282 1.142446229439669 0.2532685845577058 1.0 0.7349679861261711 40 P10644,Q9Y624,P02786,Q9NUQ9,P04439,Q08722,P30825,P15529,Q96J02,Q5ZPR3 10 +Protein insertion into mitochondrial inner membrane 0.6895915312409148 1.1422289095418872 0.2533588822169363 1.0 0.7349679861261711 4 Q9P0J0,Q53H12 2 +Skeletal muscle cell differentiation 0.599637981890993 1.138038386110922 0.2551044539615414 1.0 0.7379888580847409 6 P61201,P50402,Q9BYT8 3 +Respiratory gaseous exchange by respiratory system 0.5219996749462058 1.1369690335992984 0.2555512311146344 1.0 0.7383478848059715 10 P10253 1 +Cell activation involved in immune response 0.443360385935154 1.1364016201796945 0.2557885180385284 1.0 0.7387035371389465 38 P02786,P09601,Q04656,Q07954,P15529,P11279,P05067 7 +Positive regulation of natural killer cell mediated cytotoxicity 0.7869354808637646 1.1356693339286643 0.2560949794485463 1.0 0.7389288233954711 3 P11279 1 +Positive regulation of natural killer cell mediated immunity 0.7869354808637646 1.1356693339286643 0.2560949794485463 1.0 0.7389288233954711 3 P11279 1 +Regulation of neuron projection regeneration 0.6420798080788928 1.1308984956788388 0.2580978165466217 1.0 0.7419881607448529 5 Q96G23,P10586 2 +Leukocyte proliferation 0.4404399774486058 1.1304129430870409 0.2583022627913756 1.0 0.7419881607448529 41 P10644,P02786,P04439,Q92542,P30825,P15529,Q96J02,Q5ZPR3 8 +Glycerophospholipid biosynthetic process 0.4437981979931859 1.127647517632782 0.2594688103696314 1.0 0.7433010399050467 35 Q8NF37,Q96N66,Q9UG56,Q9UBF8,Q9NX62,O43292,Q9NTJ5,Q9NPH0,Q9BTU6,O14735,Q92643,P48651,P35790,Q9H490 14 +Glucosylceramide metabolic process 0.7847419955632338 1.1269762998988235 0.2597525015231179 1.0 0.7433010399050467 3 Q16739 1 +Lymphocyte mediated immunity 0.4430125614017514 1.124597435386698 0.260759660983197 1.0 0.7447480118765128 36 P51809,P01889,P02786,Q9NUQ9,P04439,O15400,P53634,Q07021,P15529,P11279 10 +Response to growth factor 0.3507193624201087 1.1242923861997076 0.2608890073088645 1.0 0.7447886091266747 102 P62942,P05556,P36896,P05067,O14786,P56192,Q53EL6,O00560,P08069,Q92673,P98164,Q99538,Q06481,Q04656,Q99523,P00533,O94813,Q05D32,P50402,Q9H223,Q92896,Q9H4M9,O00400 23 +Dendritic cell migration 0.6404811444221736 1.1236634614505274 0.2611558227209931 1.0 0.7452214456030457 5 Q4KMQ2 1 +Regulation of response to wounding 0.4413833128396462 1.1230798523989558 0.2614035821020981 1.0 0.7452709443007812 22 Q16625,P55011,P10586,P05556,Q04656,Q96G23,P42345,Q4KMQ2,Q9Y251 9 +Negative regulation of lyase activity 0.7829508196721291 1.1198812681291532 0.2627643616464579 1.0 0.7471747936223896 3 P04899,P08754 2 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.558883984210403 1.1189778715616687 0.2631495794888643 1.0 0.7475197081705806 8 Q9NUD5,O43657 2 +Response to thyroid hormone 0.5788874899503991 1.1182112034815952 0.2634768004748087 1.0 0.7477999209228412 7 P07858 1 +Forebrain development 0.4087048389465279 1.1174244976227692 0.2638128655135572 1.0 0.7481830017567741 60 O94901,Q96QD8,O75569,Q96N66,Q15154,O14786,P05067,P19022,P08069,P07942,Q9NQC3,O14949,P98164,Q15042,Q04656,P00533,O94813,P11166,P07196 19 +Positive regulation of lipid transport 0.5585269170846374 1.1171086781854445 0.2639478604113461 1.0 0.7482378216481148 8 Q9NV96 1 +Respiratory chain complex iii assembly 0.7821534466984084 1.116723869256179 0.2641124087848951 1.0 0.7483763348355176 3 Q9BSK2 1 +Axonal fasciculation 0.7818704641640952 1.1156034914709512 0.2645918969418037 1.0 0.7489442279114339 3 Q9NQC3 1 +Regulation of mitochondrial fusion 0.6831653770535603 1.115173864431816 0.2647759235173055 1.0 0.7489442279114339 4 P02786 1 +Positive regulation of i kappab kinase nf kappab signaling 0.4406627982231707 1.1138392387857337 0.2653481600102443 1.0 0.7497271240305182 38 Q86UE4,Q8TB61,P02786,P09601,O43657,Q8WVQ1 6 +Positive regulation of mast cell activation 0.8452966240576855 1.113430618265883 0.2655235310879575 1.0 0.7497271240305182 2 P51809 1 +Regulation of blood circulation 0.44045823654697 1.1113118960116195 0.2664341206504546 1.0 0.7497271240305182 23 O75844,P17612,P42892,P05023,P16615,Q14126,P0DP25,P10253,P20020 9 +Embryo implantation 0.511222764285855 1.111149865559797 0.266503846833745 1.0 0.7497271240305182 11 P35613,P36896 2 +Response to oxygen levels 0.4005199534836741 1.1088224589376885 0.2675067797959982 1.0 0.7497271240305182 63 Q92544,P52789,P30519,P02786,P09601,Q9Y487,P55786,Q96A26,Q04656,Q8N511,P14672,O95831,Q15904,P11166,P07237,Q9Y4P3,P19021 17 +Prenylation 0.8433300557194494 1.1054393116803287 0.2689692775638839 1.0 0.7497271240305182 2 P49356 1 +Macrophage differentiation 0.5928852072753542 1.105129950168874 0.2691032845754355 1.0 0.7497271240305182 6 P05067 1 +Sodium ion export across plasma membrane 0.8430022943297277 1.1041081252920664 0.2695462370353572 1.0 0.7497271240305182 2 P05023 1 +Cell part morphogenesis 0.3604420786262133 1.103846999080585 0.2696595132573578 1.0 0.7497271240305182 116 P05556,O14786,P05067,Q96PU5,P48681,Q15375,P19022,P98155,P08069,Q9NQC3,Q13641,P98164,Q06481,Q04656,O94813,Q9HCE1,Q92581,O00264,Q92692,O15031,P35613,P42892,O75955,P07196 24 +Regulation of extent of cell growth 0.4380553939580441 1.1032472496876349 0.269919807426781 1.0 0.7497271240305182 21 Q15375 1 +Response to camp 0.5358711130126992 1.1029499869886377 0.2700488847492175 1.0 0.7497271240305182 9 P05067 1 +Regulation of vacuole organization 0.5097458032954243 1.1025522675947634 0.2702216485486706 1.0 0.7497271240305182 11 P20339,Q15042,Q9H0U4,Q14108,P11234 5 +Peroxisomal transport 0.59226594266732 1.102111485036107 0.2704132069166691 1.0 0.7497271240305182 6 O75381,P50542,P40855,O14678 4 +Response to zinc ion 0.6355503006431733 1.1013505909095729 0.2707441006367821 1.0 0.7500829066463998 5 P19021 1 +Negative regulation of vascular associated smooth muscle cell proliferation 0.6351802572629954 1.0996762960521536 0.2714731862230106 1.0 0.7517808397588424 5 P09601,Q53EL6 2 +Head morphogenesis 0.5915091906148118 1.098422773588878 0.2720199224993735 1.0 0.7523787134522685 6 O75787,Q15042 2 +Fatty acid elongation 0.841035725991478 1.0961252795410708 0.2730239531326703 1.0 0.7541383231491223 2 Q9NZ01 1 +Regulation of lymphocyte activation 0.4171165996132913 1.095272623569072 0.2733972174178076 1.0 0.7548470334937251 55 P10644,P11279,Q9BXW9,P02786,Q9NUQ9,P04439,Q08722,P30825,Q14254,P15529,Q96J02,O96005,Q5ZPR3 13 +Protein quality control for misfolded or incompletely synthesized proteins 0.5077363849718012 1.090851339281775 0.2753383017965038 1.0 0.7585875103584258 11 Q16740 1 +Regulation of bicellular tight junction assembly 0.5893196949651046 1.0877498213864454 0.2767055669143294 1.0 0.7600492556653317 6 Q9Y624 1 +Multicellular organism growth 0.4375383488439846 1.084723323485273 0.2780442145981874 1.0 0.7608578782722818 24 O75844,Q9BZK7,Q99538,P42345,O95470,Q8WWQ0,Q15363,P05067 8 +Positive regulation of peptidase activity 0.4311768956293979 1.0843312710692836 0.278217944962051 1.0 0.761011368270405 45 P61289,Q9NR28,Q9BXK5,Q99538,Q96A26,Q92542,O95831,Q9P0J0,Q96HY6,P05067,Q9NZJ7 11 +Biological process involved in symbiotic interaction 0.3325133450053756 1.0818713227973336 0.2793097090347669 1.0 0.7628267419202732 84 P05556,Q96J02,P07237,P07858,O14786,O15118,P02786,P01130,Q9H9H4,P06756,P08195,P00533,Q9BTY2,Q14108,Q92692,Q9Y624,P35613,Q8WTV0,P11717,P15529,P11279,P51149 22 +Positive regulation of protein binding 0.4380543178654052 1.0817732213488471 0.279353308333456 1.0 0.7628267419202732 26 P62942,O75955,Q07954,Q96D46,Q9BUN8,O14786,P05067 7 +Positive regulation of erad pathway 0.6747968678216133 1.0799748313182205 0.2801533881199787 1.0 0.7633606622327238 4 Q4ZIN3 1 +Collagen metabolic process 0.499025761071645 1.079454881338122 0.2803849967895928 1.0 0.7633606622327238 12 Q9UBG0,Q92791,P05556,Q32P28,P07858 5 +Heart morphogenesis 0.4385861370239878 1.079212839322688 0.2804928573391845 1.0 0.7633606622327238 30 O75844,P98164,Q53EL6,P16870,P62942,Q9NQC3,Q15363,O94813,O14786,P10253 10 +Determination of adult lifespan 0.5868205896760166 1.0755670881108388 0.2821209132454427 1.0 0.7646471158622622 6 O75844 1 +Establishment of pigment granule localization 0.8357915437561452 1.0748747700092325 0.2824307991443628 1.0 0.7646471158622622 2 P62820 1 +Dendrite arborization 0.7709855906434345 1.0725784407788486 0.2834603021125161 1.0 0.7646471158622622 3 Q13641 1 +Protein localization to early endosome 0.5697760458611493 1.0723230654675384 0.2835749502324654 1.0 0.7646471158622622 7 Q92673 1 +Gpi anchor metabolic process 0.5697672778266968 1.072278895923998 0.2835947828799399 1.0 0.7646471158622622 7 Q9H490,Q92643 2 +Urogenital system development 0.4273949884402009 1.0720004434570083 0.2837198329580426 1.0 0.7646471158622622 47 O75844,Q15375,P98164,P39210,Q5SZK8,O95470,O76024,O00592,O94813,P07602,P14543,Q9NZJ7 12 +Production of molecular mediator involved in inflammatory response 0.4903660367843572 1.0718166348333955 0.2838023999358929 1.0 0.7646471158622622 13 Q06481,Q8IV08 2 +Phosphatidic acid metabolic process 0.6726340579456543 1.070885482441917 0.2842209242795004 1.0 0.765455936371394 4 Q9NPH0 1 +Phagosome acidification 0.8344804981973117 1.0695709011731194 0.2848124989612488 1.0 0.7666218462486599 2 Q14964 1 +Activin receptor signaling pathway 0.6721967404622224 1.0690480633975232 0.2850480125232657 1.0 0.7666218462486599 4 P62942,P36896 2 +Regulation of activin receptor signaling pathway 0.6721967404622224 1.0690480633975232 0.2850480125232657 1.0 0.7666218462486599 4 P62942,P36896 2 +Negative regulation of response to external stimulus 0.4357716640395982 1.0684826716535645 0.2853028428114013 1.0 0.7667736145188845 37 P04062,P55011,P80303,P01889,P04439,Q96G23,P01130,O94813,O43657,Q96J02,O14786 11 +Alcohol metabolic process 0.3306253649441253 1.067673409532682 0.2856678569801847 1.0 0.76679890738789 83 Q15392,P61916,P04114,Q9BW91,P05067,Q14534,P04062,O15118,P98155,Q16850,P35610,Q14849,P01130,Q13510,P00387,Q15800,Q9H2C2,Q6NUM9,Q14739,P00374,Q8WTV0,Q8TC12,P14324,Q9NX62,P16435,Q8NBN7,P51648,O15269,Q9BQE5 29 +Stress activated protein kinase signaling cascade 0.4353028581810222 1.064579684707997 0.2870661771037757 1.0 0.7671796899932951 37 O75844,Q53EL6,Q9P035,O00560,O75915,P00533,P08069,P78318,Q96J02,Q14596,P05067 11 +Attachment of gpi anchor to protein 0.6274143762790352 1.064549310337615 0.2870799287567878 1.0 0.7671796899932951 5 Q9H490,Q92643 2 +Histone h3 k36 demethylation 0.8331694526384787 1.0642706601995495 0.2872061052099137 1.0 0.7671796899932951 2 Q8IUF8 1 +Cytosolic transport 0.4011527626215301 1.0642177858890072 0.2872300516185995 1.0 0.7671796899932951 61 O95249,Q13190,O60499,O75503,Q99523,Q8NBN3,Q92673,P11279 8 +Pore complex assembly 0.4891144364832679 1.0641231065371786 0.2872729346074418 1.0 0.7671796899932951 13 Q9BTX1,Q9NQC3 2 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.5842297008861511 1.0629367851213176 0.2878106197937664 1.0 0.7671796899932951 6 P52789 1 +Vascular associated smooth muscle cell proliferation 0.5284792435214895 1.062640115882013 0.2879451874170997 1.0 0.7671796899932951 9 Q53EL6,P04899,P09601,P08754 4 +Positive regulation of exosomal secretion 0.5479620765708453 1.0617720925228582 0.2883391619907161 1.0 0.7671796899932951 8 O43633,Q8WUM4,Q99816,O00560,P51149 5 +Nik nf kappab signaling 0.4332594373014398 1.0614402772678448 0.2884898607926005 1.0 0.7671796899932951 22 O43657,P05067,P00533 3 +Leukocyte migration 0.4315533085320776 1.0614380127476597 0.2884908894402891 1.0 0.7671796899932951 42 Q9Y624,P04062,P35613,P55011,P09601,Q99538,Q08722,O94813,Q4KMQ2,P05067 10 +Cell cell signaling by wnt 0.3934508347418626 1.0613290682705003 0.2885403798796142 1.0 0.7671796899932951 64 Q9P0T7,P20339,P50402,P19022,Q9P1Z2,O75787,P16870,Q9BZK7,Q96K76,P00533,Q07954,Q8TAA9,P49815,Q16531,P05067,Q13641 16 +Negative regulation of transmembrane transport 0.4332306186760398 1.061221395491658 0.2885892982447386 1.0 0.7671796899932951 22 P62942,Q06481,Q04656,P31751,P0DP25,P21796,Q96PU5 7 +Heart valve morphogenesis 0.6698820810717252 1.0593254401750347 0.2894515927976668 1.0 0.768225835530227 4 O94813 1 +Post golgi vesicle mediated transport 0.4321151312277047 1.059126840373444 0.2895420177627781 1.0 0.768225835530227 41 Q92572,Q9BZG1,Q9H4A5,O15126,Q99523,O60826,O15127,O14828,Q92673,P11279 10 +Cellular response to increased oxygen levels 0.5670684838148066 1.05868300378889 0.289744170851075 1.0 0.768225835530227 7 Q15904,Q8N511,Q9Y487 3 +Vesicle mediated transport 0.4765363304495339 1.0586436448894234 0.2897621021322853 1.0 0.768225835530227 346 O43731,P20339,Q8IX05,Q13501,O60499,P05556,Q96L92,Q5SQN1,Q9Y282,P05067,P51151,P24390,P02786,P98155,O95197,Q9H0U4,Q8NBN3,P08069,Q14849,P50897,Q92673,Q9UID3,Q8TBA6,Q9BZG1,Q9UBG0,O15126,Q06481,Q99523,Q7L0J3,P04899,P61019,P49815,P49755,O75503,Q8WUM4,O60826,O00429,P11717,Q07954,P08754,Q12907,Q5KU26,P11279,Q9UBF8,O95772,Q96CW1,Q4J6C6,O43633,Q9UPT5,P09601,Q9P2W9,P51572,Q08722,Q9BRK5,Q15036,O15127,O00743,Q13277,Q08380,O15118,P61020,Q9H4A5,O15400,O00560,P01130,P06756,P98164,Q96JJ3,P16615,Q15904,Q14108,O95249,Q13190,O15260,P51790,Q4KMQ2,Q86Y82,P11233,P31751,Q08431,Q9NR31,Q96PU5,P14672,O95070,P0DP25,Q9Y6B6,P20645,Q9UNK0,Q92544,Q15042,Q9Y3B3,P51809,Q9H223,Q8WTV0,O43760,O75955,Q6NUQ1,Q15363,O14828,Q9H4M9,Q8NHH9,Q6IAA8,P62820,Q9NX40,P51148,O14786,Q92572,P19022,P27824,Q6DD88,O15258,Q7Z6M1,Q14964,Q9NPF0,Q9HCU5,P57105,P51149 117 +Tight junction organization 0.4519193845289204 1.0557832481999057 0.2910672532975853 1.0 0.7697931568201469 17 Q9Y624,P17612,Q9BTW9,Q16625,Q8WUM4,P36404 6 +Interleukin 10 production 0.6252975750139953 1.054978936831292 0.291434958116509 1.0 0.7699015235366292 5 Q08722 1 +Positive regulation of tumor necrosis factor superfamily cytokine production 0.47926838718671 1.052497048814886 0.292571563816022 1.0 0.7709350086866992 14 P15260 1 +Blastoderm segmentation 0.6678306645654273 1.0507123622330106 0.2933907165275875 1.0 0.7727787236225422 4 Q9Y2W6 1 +Cellular response to osmotic stress 0.4939590554110461 1.049146741753228 0.2941105861551889 1.0 0.7734169595537742 12 O95202,P11166,P14672 3 +Cell cell adhesion mediated by integrin 0.8289085545722885 1.0470706994726768 0.2950669718999481 1.0 0.7743526930487094 2 O00592 1 +Fatty acid derivative biosynthetic process 0.4781246438288394 1.0452584883128275 0.2959035178878357 1.0 0.7743526930487094 14 P50897,Q9UMR5 2 +Positive regulation of phosphatase activity 0.5802594304015586 1.043583091411736 0.2966783192091504 1.0 0.7744504849102026 6 P42345,P0DP25 2 +Positive regulation of phosphoprotein phosphatase activity 0.5802594304015586 1.043583091411736 0.2966783192091504 1.0 0.7744504849102026 6 P42345,P0DP25 2 +Regulation of l glutamate import across plasma membrane 0.8279252704031458 1.043107247123611 0.2968986246061682 1.0 0.7744504849102026 2 P05556 1 +L glutamate import across plasma membrane 0.8279252704031458 1.043107247123611 0.2968986246061682 1.0 0.7744504849102026 2 P05556 1 +Regulation of amino acid transmembrane transport 0.8279252704031458 1.043107247123611 0.2968986246061682 1.0 0.7744504849102026 2 P05556 1 +Regulation of potassium ion transmembrane transporter activity 0.5443136411475108 1.0426525048864554 0.2971092624285221 1.0 0.7746875528617934 8 P54709,Q96PU5 2 +Positive regulation of stress activated protein kinase signaling cascade 0.4924027383595381 1.0398329104873192 0.298417536193529 1.0 0.7767375147492536 12 O00560,P05067,O75915 3 +Negative regulation of cell differentiation 0.3617420254970118 1.0383222680433768 0.2991200449287201 1.0 0.7767995064808874 74 Q15375,Q06481,Q96G23,Q99523,Q9NQC3,Q92673,Q14596,P01130,P05067 9 +Insulin receptor signaling pathway 0.4333768474168276 1.037610544205838 0.2994514069462997 1.0 0.7770849011750359 32 Q92572,Q9UQB8,P08069,P04899,Q92673,Q15043,O14654,P31751,P43490 9 +Steroid catabolic process 0.6645098667775319 1.0367778378445638 0.299839406359458 1.0 0.7771984429880127 4 Q15036,Q8WTV0 2 +Synapse organization 0.3910982180864837 1.0362631258476018 0.300079403931925 1.0 0.7771984429880127 64 O15258,Q15375,O15031,P19022,P10586,Q99538,O00560,Q9BRK5,Q12834,P08069,P07196,O00264,O14786,P05067,Q13641 15 +Intraciliary transport involved in cilium assembly 0.825958702064896 1.0351870348635237 0.3005815724338956 1.0 0.7771984429880127 2 A0AVF1 1 +Negative regulation of developmental process 0.3392408161336823 1.034835655973525 0.3007456680864531 1.0 0.7771984429880127 96 Q15375,P06756,P02786,Q06481,Q96G23,Q99523,P01130,Q92673,Q14596,Q9NQC3,P05067 11 +Macropinocytosis 0.7610738237170234 1.033535392277081 0.3013534166012359 1.0 0.7771984429880127 3 Q06481 1 +Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.663532788276917 1.0326799256772032 0.3017537108837205 1.0 0.7771984429880127 4 O43657 1 +Cell migration involved in sprouting angiogenesis 0.5229719714320064 1.0325882188448194 0.3017966438067534 1.0 0.7771984429880127 9 O94813,O14786,P09601 3 +Fat soluble vitamin metabolic process 0.5773112921587917 1.0292137176228913 0.3033792576341376 1.0 0.7776456329920023 6 Q99538,P98164,P38435 3 +Regulation of lipid catabolic process 0.5222201399890224 1.0284847894465416 0.3037218421740244 1.0 0.7776456329920023 9 P01130,Q92673,P31751 3 +Response to uv a 0.6621777508851132 1.026998455198828 0.3044211914958874 1.0 0.7776456329920023 4 P00533 1 +Response to dsrna 0.4475063019753492 1.0250551538041863 0.3053371643320699 1.0 0.7779543584340923 17 P08195,Q9NUD5,Q5KU26 3 +Nuclear pore organization 0.482512036379885 1.0235162970987357 0.3060637984317518 1.0 0.778775204829574 13 Q9NQC3 1 +Regulation of reproductive process 0.4469559560456213 1.0212217515199844 0.3071493891345098 1.0 0.7792637852836065 17 Q07021,P36896 2 +Intracellular sterol transport 0.520879112600379 1.021165211565903 0.307176171351553 1.0 0.7792637852836065 9 P01130,O15118,Q9H2C2 3 +Neural tube patterning 0.6174889000251448 1.0196977399600835 0.3078718338700597 1.0 0.7801108081885687 5 O75386,O75787 2 +Embryonic camera type eye development 0.8220255653883961 1.0193741653568715 0.3080253662621586 1.0 0.7801942421103775 2 O75386 1 +Positive regulation of cytokine production 0.3942331729193963 1.0171057408486617 0.3091031295841346 1.0 0.7820055319827013 62 O75787,P09601,Q9NUQ9,P04439,O75955,P15529,P15260,Q92673,Q9NUD5,P05067,Q5ZPR3,Q9Y251 12 +Adenylate cyclase modulating g protein coupled receptor signaling pathway 0.4734037061994726 1.0153695318983464 0.3099297110136672 1.0 0.7822247717850759 14 P48960,P08754,P04899,P07602,Q9NZJ7 5 +Sperm capacitation 0.8203867584398754 1.0127966563514144 0.3111572981408677 1.0 0.7822247717850759 2 P09622 1 +Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning 0.8203867584398548 1.0127966563513315 0.3111572981409072 1.0 0.7822247717850759 2 O75386 1 +Smoothened signaling pathway involved in dorsal ventral neural tube patterning 0.8203867584398548 1.0127966563513315 0.3111572981409072 1.0 0.7822247717850759 2 O75386 1 +Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning 0.8203867584398548 1.0127966563513315 0.3111572981409072 1.0 0.7822247717850759 2 O75386 1 +Cardiac epithelial to mesenchymal transition 0.8200589970501693 1.011481963399193 0.3117858094858503 1.0 0.7822247717850759 2 Q9NQC3 1 +Positive regulation of endothelial cell apoptotic process 0.8200589970501615 1.011481963399161 0.3117858094858656 1.0 0.7822247717850759 2 Q4KMQ2 1 +Endothelial cell apoptotic process 0.8200589970501615 1.011481963399161 0.3117858094858656 1.0 0.7822247717850759 2 Q4KMQ2 1 +Cell cell adhesion 0.3448918785676128 1.011271524465134 0.3118864910493826 1.0 0.7822247717850759 105 Q08722,Q14126,O00592,Q96J02,Q5ZPR3,Q15375,P02786,P07942,P10644,P06756,Q96JJ3,Q9NUQ9,P30825,P00533,Q14574,Q9Y624,O15031,P35613,P10586,P04439,P15529,Q96J84 22 +Regulation of lipid metabolic process 0.4083528932249585 1.0104115224834302 0.3122981696909459 1.0 0.7827107399391257 55 Q8NBJ4,O75844,Q6IAA8,Q96N66,P61916,Q8WTV0,Q06481,Q96G23,P04114,P16435,P31751,P07602,Q92673,Q9H2C2,P01130,Q13510,Q9NZJ7 17 +Cartilage development involved in endochondral bone morphogenesis 0.6579908237930201 1.0094558758556238 0.3127560527483304 1.0 0.7829794524879835 4 O75844 1 +Synaptic signaling 0.3303332845763149 1.0086156781056124 0.313158985359123 1.0 0.7836849037865249 82 P20339,Q13501,P55011,P05556,Q12834,Q5SQN1,P54920,Q13277,P05067,P19022,P17612,O00560,P50897,P0DP25,Q13641,Q9UQB8,Q15042,Q99538,P16615,Q92542,Q7L0J3,P04899,O75955,P51790,Q96A49,P57105,Q4J6C6 27 +Cellular response to gamma radiation 0.4993055985355977 1.0079829269957243 0.3134626585397444 1.0 0.7841415073834519 10 Q86UE8 1 +Positive regulation of bone mineralization 0.7544049139929017 1.0073511799340142 0.3137660431367002 1.0 0.784597036355359 3 Q4KMQ2 1 +Negative regulation of microtubule polymerization 0.6146701573751525 1.0069728796919224 0.3139478071366175 1.0 0.7847482087970552 5 Q15691,P04350,Q9BTW9 3 +Regulation of axon guidance 0.6570750856194807 1.0056217497009294 0.3145975573859234 1.0 0.7854618289191582 4 O94813 1 +Aerobic respiration 0.3294353934690555 1.0037893795430748 0.3154801445813469 1.0 0.7870578693778376 87 O75964,P14406,Q7KZN9,Q15070,Q9Y6M9,Q15526,Q9UDW1,P03886,O75438,P03915,O14949,Q13423,Q04656,O96000,P00403,O43676,O95169,Q9BSK2,Q9H3K2,P09622,P13073 21 +Ire1 mediated unfolded protein response 0.5559818041846376 1.0028314835793553 0.3159421755457128 1.0 0.7874417987444146 7 Q96HY6,P57088 2 +Associative learning 0.4861145124523626 1.002185786974901 0.3162538710010603 1.0 0.7874697041977903 12 Q99538,P05067,P50897,Q13641 4 +Positive regulation of amyloid precursor protein biosynthetic process 0.8171091445427889 0.9996621030934316 0.3174740578083466 1.0 0.7876952063531643 2 Q92542 1 +Positive regulation of hormone biosynthetic process 0.8167813831530634 0.9983501804339672 0.3181095825552811 1.0 0.7876952063531643 2 P16435 1 +Positive regulation of steroid hormone biosynthetic process 0.8167813831530634 0.9983501804339672 0.3181095825552811 1.0 0.7876952063531643 2 P16435 1 +Positive regulation of steroid biosynthetic process 0.8167813831530634 0.9983501804339672 0.3181095825552811 1.0 0.7876952063531643 2 P16435 1 +Positive regulation of steroid metabolic process 0.8167813831530634 0.9983501804339672 0.3181095825552811 1.0 0.7876952063531643 2 P16435 1 +Positive regulation of hormone metabolic process 0.8167813831530634 0.9983501804339672 0.3181095825552811 1.0 0.7876952063531643 2 P16435 1 +Branching involved in blood vessel morphogenesis 0.6552082411862169 0.997808561345324 0.3183721979010305 1.0 0.7876952063531643 4 Q14344,O14786 2 +Regulation of wnt signaling pathway 0.4213502425172786 0.9972899950690174 0.3186237686376032 1.0 0.7876952063531643 45 Q9P0T7,P50402,P19022,O75787,Q9BZK7,Q96K76,P00533,Q07954,P49815,P05067,Q13641 11 +Negative regulation of cytokine production involved in inflammatory response 0.7518032786884971 0.9971568758825444 0.3186883694006794 1.0 0.7876952063531643 3 Q06481,Q53EL6 2 +Organ growth 0.4228269734788135 0.9946831866492192 0.3198903743383401 1.0 0.7892337267714424 20 P10644,O75844,P07602,Q9NZJ7 4 +Lipid homeostasis 0.4271147123920423 0.9937140335641712 0.320362108585174 1.0 0.7894458138523686 27 Q6IAA8,O15118,P61916,O15260,Q8WTV0,Q15067,Q9Y6C9,P04114,P01130,Q9BWH2,Q9Y6B6,Q9H4M9,Q9NQC3 13 +Leukotriene biosynthetic process 0.7508196721311428 0.9933058520157052 0.3205609265569089 1.0 0.7894458138523686 3 Q99735,P09960 2 +Negative regulation of blood pressure 0.6538563688603095 0.992153377731148 0.3211227114725754 1.0 0.7897157051085443 4 Q9HB40 1 +Postsynaptic cytoskeleton organization 0.6535211355885331 0.9907513860532728 0.3218069926182521 1.0 0.7904058492311792 4 P07196 1 +Activation of phospholipase d activity 0.7501639344262241 0.9907394870583696 0.3218128043251966 1.0 0.7904058492311792 3 P40616,Q14344 2 +Adipose tissue development 0.4768727128850781 0.98881135506782 0.3227554475635328 1.0 0.7911874139241752 13 O15173,Q92673 2 +Response to lead ion 0.610452155622372 0.9879442394186466 0.3231799576089234 1.0 0.7913138326162472 5 P05067 1 +Positive regulation of smoothened signaling pathway 0.6526070487837619 0.9869292987347378 0.3236772998535528 1.0 0.7916387628118992 4 P16435 1 +Amyloid beta clearance by transcytosis 0.6101383403939569 0.9865292065601838 0.3238734903867348 1.0 0.7916387628118992 5 Q07954 1 +Dicarboxylic acid transport 0.4514041610014412 0.985292375317074 0.324480476880788 1.0 0.792697962591321 16 P98164,P55011,Q15042,P05556,Q9UBX3,O75915,Q9H2D1,O60831 8 +Regulation of cyclic nucleotide phosphodiesterase activity 0.7483111841884182 0.9834926959578184 0.325365008362239 1.0 0.7932007263506158 3 P0DP25 1 +Regulation of ion transport 0.3603862825303218 0.9826457139721424 0.3257818371437211 1.0 0.7932007263506158 73 P54709,P51809,O75844,P20020,P55011,Q15042,P62942,P05023,P05556,Q04656,O75915,Q7L0J3,O76024,P0DP25,Q4KMQ2,P21796,P05067,Q96PU5 18 +Lipid phosphorylation 0.8128482464765817 0.98262950487643 0.3257898175782325 1.0 0.7932007263506158 2 Q8TCT0 1 +Neuron apoptotic process 0.4117976756752143 0.9797560613206554 0.3272065458106263 1.0 0.7952999623078443 51 P04062,Q15375,P09601,Q9NR28,Q99538,Q96A26,Q99720,Q92542,O95831,O76024,Q01105,P50897,P07196,O14786,P05067,P31751 16 +Negative regulation of organic acid transport 0.746911257758833 0.9780213901968836 0.3280637448935946 1.0 0.7960899370482993 3 P31751 1 +Phosphatidylcholine acyl chain remodeling 0.8115372009177306 0.977398671028476 0.3283718206881136 1.0 0.7960899370482993 2 Q96N66 1 +Interleukin 12 production 0.6080494117580952 0.9771125431328548 0.3285134386871138 1.0 0.7960899370482993 5 Q08722,P01889 2 +Response to corticosteroid 0.4253010105198865 0.976930785370881 0.3286034196211149 1.0 0.7960899370482993 28 P04062,P16278,O95831,O94813,P16435,P0DP25,P07196,Q9H7B4,P19021,P20020 10 +Amide transport 0.4257834674258338 0.9763830201131726 0.3288746927386803 1.0 0.7960899370482993 32 P98164,P16870,Q03518,P07602,Q9H2D1,Q9NZJ7 6 +Layer formation in cerebral cortex 0.6500491964578363 0.9762401033220156 0.3289454941614012 1.0 0.7960899370482993 4 P35222,Q00535,Q96N66 3 +Carbohydrate mediated signaling 0.6068438823952846 0.971680271597883 0.3312096343964263 1.0 0.8000728621771778 5 Q5KU26,Q9NWS0 2 +Regulation of ire1 mediated unfolded protein response 0.5646078568275154 0.9673360812664744 0.3333760520326516 1.0 0.8006153468764302 6 Q96HY6,P57088 2 +Regulation of endocytic recycling 0.7437630280598273 0.9657312488228362 0.3341786786418952 1.0 0.8006153468764302 3 Q92673 1 +Cobalamin transport 0.8082595870206477 0.9643428190131312 0.3348740799896852 1.0 0.8006153468764302 2 Q9NPF0 1 +Nuclear pore complex assembly 0.5104380321416366 0.9641707031594754 0.3349603499035329 1.0 0.8006153468764302 9 Q9NQC3 1 +Regulation of growth 0.3493730525756018 0.9637823487491364 0.3351550580255442 1.0 0.8006153468764302 115 O75844,Q6IAA8,O75629,O95470,Q9P0J0,Q96J02,P36896,P05067,Q96PU5,O14786,Q9NVI7,Q15375,P02786,O00560,P50897,Q9NQC3,Q99538,P00533,O94813,Q9BSK2,O76024 21 +Regulation of mitochondrial fission 0.5102123053544214 0.9629386479580934 0.3355783130275733 1.0 0.8006153468764302 9 Q9NUQ9 1 +Regulation of fibroblast migration 0.4912745265722114 0.9622687345460864 0.335914630032089 1.0 0.8006153468764302 10 Q06481 1 +Fibroblast migration 0.4384816063357769 0.9621686515712768 0.3359648933643675 1.0 0.8006153468764302 17 O95470,Q06481,Q5SNT2 3 +Salivary gland development 0.7427715035869125 0.9618646375615086 0.3361176039327551 1.0 0.8006153468764302 3 P00533 1 +Regulation of release of cytochrome c from mitochondria 0.4855695135387437 0.961579404991868 0.3362609209249128 1.0 0.8006153468764302 11 Q9H3K2,Q96A26 2 +Polysaccharide metabolic process 0.4171978632253924 0.9595635989283328 0.3372748966610426 1.0 0.8027341083518339 19 Q7LGA3,O43505,P10253,P31751 4 +Peroxisome organization 0.5092831912444388 0.957867532884038 0.3381295599919005 1.0 0.8044722778917266 9 O75381,P40855,O14678,O00429,P50542,Q7Z434 6 +Dna replication checkpoint signaling 0.5623929385170378 0.9565574885334202 0.338790654638833 1.0 0.8054526809476703 6 Q9Y619 1 +Epithelial tube morphogenesis 0.4200637295882579 0.9555902617687134 0.3392792833835705 1.0 0.8057935957979858 41 Q15375,O15031,P98164,P17612,O75386,O00592,O94813,Q13308,P49815,Q15363,O60313,O14786,P11233 13 +Tumor necrosis factor superfamily cytokine production 0.4273858858814672 0.9552875535177106 0.3394322999767369 1.0 0.8057935957979858 18 P05067,P15260 2 +Positive regulation of peptidyl threonine phosphorylation 0.5462629737536209 0.9539002851127908 0.340134119148777 1.0 0.8062761512544663 7 P05067 1 +Response to catecholamine 0.4710991089068784 0.9532708010549744 0.3404528817024852 1.0 0.8067361508180867 13 Q92542,P05067,P17612 3 +Purinergic nucleotide receptor signaling pathway 0.8053097345132906 0.9526192443643118 0.340783023068949 1.0 0.806927297303531 2 Q4KMQ2 1 +Gamma aminobutyric acid signaling pathway 0.8053097345132738 0.952619244364246 0.3407830230689823 1.0 0.806927297303531 2 P55011 1 +Regulation of vascular permeability 0.5458682104418175 0.951913907778335 0.3411406455634012 1.0 0.8069463369715555 7 Q16625 1 +Developmental growth involved in morphogenesis 0.4161438846414007 0.9510675401072484 0.341570091221697 1.0 0.8069463369715555 45 Q15375,O94813,Q92581,Q9NQC3,P05067 5 +Establishment of protein localization to endoplasmic reticulum 0.4194526432089395 0.9508316337583712 0.3416898513711643 1.0 0.8069463369715555 23 Q9Y5M8,P33908,Q15042,Q15629 4 +Tube morphogenesis 0.3452598909720875 0.9505648009593562 0.34182534401342 1.0 0.8069463369715555 111 P52789,P55011,P09601,O95470,P04114,O00592,Q08431,O14786,Q86UE4,Q15375,Q9NZ08,Q13685,P01130,P06756,P98164,P00533,O94813,Q9Y251,O15031,P35613,P43121,Q07954,Q15363,O60313,P11233 25 +Regulation of small gtpase mediated signal transduction 0.419401445525858 0.949891706551944 0.3421672813099197 1.0 0.8069463369715555 41 Q9Y624,Q14344,Q9H0H5,P06756,Q13501,Q9NUQ9,P05556,O75955,Q15555,Q5HYI8,Q96AG4,O94813,P49815,O14786 14 +Regulation of tor signaling 0.4461096070533048 0.9496035668407862 0.3423137254165582 1.0 0.8069463369715555 16 P04062,O75844,Q6IAA8,Q9HB90,Q9NWS0,P49815 6 +Regulation of potassium ion transport 0.4834817662645176 0.9493964432775892 0.3424190186393598 1.0 0.8069463369715555 11 P54709,Q4KMQ2,Q96PU5 3 +Positive regulation of defense response 0.419268524464192 0.9487479166043946 0.342748837229929 1.0 0.8071504288461634 41 P51809,Q9NUD5,P11279,P53634,Q08722,Q99735,P01130,P05067 8 +Response to arsenic containing substance 0.4769364045740755 0.9472150725209206 0.3435291964461728 1.0 0.8083995532230964 12 Q96QD8,P09601 2 +Interleukin 6 production 0.4621324314479184 0.9439688317261526 0.345185575917815 1.0 0.8092864599447904 14 P04062,Q08722,P05067 3 +Dna methylation involved in gamete generation 0.8030154047853317 0.9435189610375688 0.3454155214715988 1.0 0.8092864599447904 2 Q9Y2W6 1 +Positive regulation of carbohydrate metabolic process 0.5441305268500283 0.94317155020462 0.3455931628069191 1.0 0.8092864599447904 7 P05067 1 +Positive regulation of neurotransmitter transport 0.737886912095576 0.9428464885583688 0.3457594290681496 1.0 0.8092864599447904 3 Q15042 1 +Epithelial tube formation 0.4203550656109485 0.94082515511831 0.3467944676290686 1.0 0.8098113051675803 27 O15031,P98164,P17612,O75386,O00592,Q15363,P49815,O60313,P11233 9 +Lipid droplet organization 0.5061294796083193 0.9406567640533358 0.3468807824147903 1.0 0.8098113051675803 9 Q15042,O95674,Q8N0X7,Q96CS3,Q9NP72,Q14534 6 +Cell growth 0.3348789473452871 0.9406521366933568 0.3468831545245578 1.0 0.8098113051675803 99 Q9NVI7,Q15375,Q6IAA8,P02786,O00560,Q9NQC3,P00533,Q9P0J0,O94813,P50897,Q92581,O14786,Q96J02,P36896,P05067,Q96PU5,Q9BSK2 17 +Neuromuscular junction development 0.5060244569215689 0.9400836940539008 0.3471746321212885 1.0 0.810199384990121 9 P05067 1 +Protein localization to microtubule end 0.8017043592264999 0.93832606605621 0.3480768681687696 1.0 0.8105504896269873 2 Q15555 1 +Cell adhesion mediated by integrin 0.5429386275129239 0.9371764114826876 0.3486678213254759 1.0 0.8114093667307947 7 O00592,P06756 2 +Regulation of water loss via skin 0.5989119867249102 0.9359815959558307 0.3492826634990664 1.0 0.8118970715686169 5 Q16739 1 +Regulation of generation of precursor metabolites and energy 0.4190492276486482 0.9323709334279152 0.3511448609445258 1.0 0.8134886060982794 38 Q9NZ45,Q9H3K2,P14406,Q04656,P05067,Q9BSK2 6 +Embryonic morphogenesis 0.3529927352295104 0.9322160763121689 0.3512248688873851 1.0 0.8134886060982794 74 P54802,P10644,O15031,O75569,P06756,P98164,P42892,O75386,P05556,Q5SZK8,P09622,Q9NX62,Q15363,O60313,P07942,P11233 16 +Regulation of cellular response to growth factor stimulus 0.420235830638461 0.9317647588478436 0.3514581108966532 1.0 0.8135450269572764 33 Q92896,P98164,O00560,Q92673 4 +Glutamine transport 0.7994100294985413 0.9292514961084344 0.352758765566094 1.0 0.8146970629267843 2 Q96QD8 1 +Apical junction assembly 0.4150293716644395 0.9291178052696076 0.3528280379655841 1.0 0.8146970629267843 21 Q9Y624,P17612,Q16625,Q9BTW9,Q8WUM4,P36404,Q16513 7 +Myeloid leukocyte migration 0.417812799510027 0.9285098066941744 0.3531431832147702 1.0 0.8146970629267843 25 Q99538,O94813,Q08722,P35613 4 +Positive regulation of response to wounding 0.4670595958687869 0.9284054461247754 0.3531972945550903 1.0 0.8146970629267843 13 Q16625,P05556,Q04656,P42345,Q4KMQ2,Q9Y251 6 +Retinal metabolic process 0.7987545067191254 0.9266618475290394 0.3541021323646163 1.0 0.8150031867424431 2 Q8NBN7 1 +Neuronal stem cell population maintenance 0.5967675118116884 0.9263444868080772 0.3542669836283296 1.0 0.8150031867424431 5 Q9BXW9,P19022 2 +Positive regulation of hydrolase activity 0.3304316037256474 0.9246796498616586 0.3551325679575821 1.0 0.8150031867424431 95 Q14344,P61289,P51572,Q96A26,P05556,Q8TC07,O75915,Q9P0J0,P07602,P05067,P42345,O95831,P0DP25,Q8IZ81,Q15042,Q9BXK5,Q9NR28,Q99538,Q92542,P00533,P49815,Q96HY6,Q9NZJ7,Q9Y624,Q15555,P31751 26 +Blood vessel morphogenesis 0.342333982625592 0.9240128740826608 0.3554796129610837 1.0 0.8150031867424431 77 Q86UE4,P52789,P06756,P98164,P35613,P09601,P55011,P43121,Q07954,P04114,Q9NZ08,O94813,Q13685,O95470,Q08431,O14786,P01130,Q9Y251 18 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.4724850960135683 0.9205566744930016 0.3572819308840618 1.0 0.8150031867424431 12 Q9NUD5,O43657 2 +Cardiac muscle contraction 0.4417844480296017 0.9204486838673128 0.3573383377270245 1.0 0.8150031867424431 16 P17612,P16615,P05023,P42345,Q14126,P0DP25,P10253,Q96PU5 8 +Positive regulation of secretion 0.415938604728396 0.920085600168986 0.357528028687053 1.0 0.8150031867424431 41 P49755,P20339,P51809,P55011,Q15042,Q9H4A5,Q8WUM4,O00560,O00429,P04899,P11279,P51149,P51151 13 +Ganglion development 0.7319776760684464 0.9199095146634488 0.3576200463547052 1.0 0.8150031867424431 3 O14786 1 +Peroxisome fission 0.7964601769911657 0.9176090845160948 0.3588235601173948 1.0 0.8158092785717318 2 P40855 1 +External encapsulating structure organization 0.4181590805425799 0.9165774233937248 0.3593641193093435 1.0 0.8158092785717318 30 P13674,P39210,Q92791,P05556,Q04656,O75955,Q07954,P07942,P14543,P05067 10 +Negative regulation of adenylate cyclase activity 0.7961324156014404 0.9163172469472513 0.3595005246404439 1.0 0.8158092785717318 2 P04899 1 +Regulation of body fluid levels 0.4089205367696815 0.915829090380616 0.3597565431662399 1.0 0.8158092785717318 48 Q14344,P52789,Q9UNS2,Q9UNN8,Q86YV9,Q13505,P04062,P17612,O00186,P49257,P19021,Q04656,P00403,P04899,Q9Y251,Q9Y624,P38435,O76024,Q9BWH2,Q4KMQ2,Q16739 21 +Regulation of atp metabolic process 0.41553416803844 0.9155961385395016 0.3598787574089688 1.0 0.8158092785717318 24 P14406,P05067,Q9BSK2 3 +Regulation of anatomical structure size 0.325587769543144 0.9152547931727596 0.3600578855685983 1.0 0.8158092785717318 90 P20339,Q15375,P54105,P42892,P55011,Q9NUQ9,P07196,Q04656,P42345,P51790,Q9HB40,O15511,O94813,Q4KMQ2,Q96J84,O14786,Q9NQC3,P20020 18 +Heterotypic cell cell adhesion 0.4776282500365326 0.9152437926406852 0.3600636592601252 1.0 0.8158092785717318 11 P06756,O75955,P05556,Q08722,Q14254,Q14126 6 +Regulation of phospholipase activity 0.4775264816581311 0.9146501363401064 0.3603753293438529 1.0 0.8158092785717318 11 Q07954,P50897 2 +Apoptotic dna fragmentation 0.5536633981955339 0.9141203370954244 0.3606536173626038 1.0 0.8158092785717318 6 O00115 1 +Transepithelial transport 0.5934558140221402 0.9114755190195564 0.3620448788111825 1.0 0.816398675169107 5 P51798 1 +Neurofilament cytoskeleton organization 0.7948213700426072 0.9111534824613812 0.3622145100098417 1.0 0.816398675169107 2 P07196 1 +Regulation of membrane repolarization 0.5932050055378426 0.9103501337112572 0.3626378870557316 1.0 0.8165567053105596 5 O75844 1 +Regulation of short term neuronal synaptic plasticity 0.794165847263204 0.9085737693341396 0.3635751577862249 1.0 0.818075720250118 2 Q15042 1 +Skin epidermis development 0.4485223625464777 0.9080232942852204 0.3638659145820162 1.0 0.8184452717076018 15 O75844,Q04656,P36896,Q9Y251 4 +Lipid biosynthetic process 0.3559432580043466 0.907166940095972 0.364318523418413 1.0 0.8188938596225551 129 Q15392,Q96N66,P05023,O95470,P04114,Q9BTU6,Q99805,Q14534,P04062,Q8NCC3,Q9UG56,Q16850,P42345,P35610,Q9NRX5,Q14849,P08069,Q9NPH0,Q53GQ0,Q9H490,P01130,Q53H12,P19021,Q13510,Q8NF37,Q06136,Q15800,Q96G23,P07686,O14735,Q9H2C2,Q92643,P35790,P27544,Q14739,Q8NBX0,Q8WTV0,Q9P035,Q9NX62,O43292,P16435,P48651,O15269,Q16739,Q9NZ01 45 +Regulation of anion transmembrane transport 0.5516791427486525 0.9044859051832724 0.3657378048664941 1.0 0.8192939811847243 6 P05556,O75915 2 +Protein localization to phagophore assembly site 0.72770431535203 0.9033737771210848 0.3663275524914553 1.0 0.819662111329112 3 Q9Y4P8 1 +Cell communication by electrical coupling 0.5514023683016359 0.9031424368812035 0.3664503038175462 1.0 0.819662111329112 6 P05023,P0DP25 2 +Cellular response to oxygen levels 0.4158594266574862 0.902314766935315 0.3668896833756443 1.0 0.819662111329112 37 P09601,Q9Y487,P55786,Q96A26,Q04656,P14672,Q8N511,O95831,Q15904,Q9Y4P3 10 +Phosphatidylcholine metabolic process 0.469087558057907 0.9002146906844307 0.368006009682833 1.0 0.8201070366602733 12 P35790,P01130,Q8WTV0,Q8NCC3 4 +Positive regulation of striated muscle cell differentiation 0.7918715175352325 0.8995563344268743 0.3683564035602316 1.0 0.8201070366602733 2 P42345 1 +Anterior posterior axis specification 0.5168878440897868 0.898993661980883 0.3686560366048592 1.0 0.8201070366602733 8 Q9Y2W6 1 +Regulation of synaptic vesicle endocytosis 0.7915437561455405 0.8982696145394498 0.369041827750511 1.0 0.8201070366602733 2 P0DP25 1 +Regulation of cation channel activity 0.4383518000446322 0.8973144879123108 0.3695511277749692 1.0 0.8204790701148496 16 P62942,P05556,P05067,P0DP25 4 +Midbrain development 0.408804984516299 0.8966671615426968 0.3698965484343015 1.0 0.8204790701148496 19 O14949 1 +Cotranslational protein targeting to membrane 0.4618852266985017 0.8965630407224151 0.3699521272038568 1.0 0.8204790701148496 13 P43307 1 +Response to insulin 0.3804004672003666 0.8964565792065375 0.3700089607807846 1.0 0.8204790701148496 63 Q15043,O14654,Q92572,P56192,O00186,P42345,P14672,P08069,Q92673,P20020,Q9UQB8,Q06481,Q99523,P04899,P49815,Q9BSK2,P11166,Q96A49,P31751,P43490 20 +Carbohydrate catabolic process 0.4050306000843933 0.8914422806848626 0.372691943634948 1.0 0.8249939121612386 49 O00462,P16278,P07686,P08236,Q99519,P10253,Q14108,P17900,P05067,Q9BRR6 10 +Maintenance of protein location 0.4146462911053646 0.8885716211726964 0.3742333484037612 1.0 0.8250202018511724 30 O43731,P52789,O94901,O15258,P24390,Q14145,O60826,P36404,O43292,Q92673,P63208 11 +Cellular response to insulin stimulus 0.3974589623507361 0.8882097054206464 0.3744279590966892 1.0 0.8250202018511724 54 Q92572,P56192,Q9UQB8,Q06481,P14672,P08069,P04899,P31751,P49815,Q92673,Q9BSK2,Q15043,O14654,P20020,P43490 15 +Response to peptide hormone 0.3219368511937151 0.8878331410345036 0.374630513126938 1.0 0.8250202018511724 88 Q15043,O14654,Q92572,P56192,P42345,P14672,P08069,Q92673,P20020,Q9UQB8,Q06481,Q99523,P09960,P04899,Q9BSK2,P35613,P11166,P16435,P07196,P31751,P43490 21 +Regulation of developmental growth 0.4067548613394695 0.8857220236968187 0.3757673374784172 1.0 0.8250202018511724 47 O75844,Q15375,Q99538,O95470,Q9NQC3,P05067,Q96PU5 7 +Calcium mediated signaling using intracellular calcium source 0.7876106194690246 0.8828586065675604 0.3773126707613836 1.0 0.8250202018511724 2 P17612 1 +N terminal protein amino acid modification 0.5135711231142002 0.8816538406657506 0.3779640299027853 1.0 0.8250202018511724 8 Q86UY6 1 +Phospholipid biosynthetic process 0.4051008819619069 0.880980423780913 0.378328415733147 1.0 0.8250202018511724 48 Q8NF37,Q96N66,Q9UG56,P14324,Q9UBF8,Q9NX62,P07686,Q9NTJ5,Q9NRX5,O43292,Q9BTU6,Q9NPH0,O14735,Q92643,P48651,P35790,Q9H490,O15269 18 +Respiratory electron transport chain 0.4025618309907345 0.8805251213879323 0.3785749023551878 1.0 0.8250202018511724 50 P04062,O14949,Q9H3K2,P09622,O96000,Q9Y6M9,Q7KZN9,P00403,Q9UDW1,O43676,P03886,O75438,P13073,P03915 14 +Heart process 0.4125948238185805 0.88008387958003 0.3788138713180884 1.0 0.8250202018511724 27 O75844,P20020,P17612,P05023,P16615,P42345,Q02487,Q14126,P04899,P0DP25,P10253,Q96PU5 12 +Response to nicotine 0.5858762646066837 0.8775135148004921 0.3802077814409377 1.0 0.8250202018511724 5 P09601 1 +Positive regulation of nik nf kappab signaling 0.4515747872506052 0.8771040046968333 0.3804301497132933 1.0 0.8250202018511724 14 P05067,P00533 2 +Regulation of ryanodine sensitive calcium release channel activity 0.5852344221876817 0.8746423963085306 0.3817685118891436 1.0 0.8259905841251791 5 P62942,P0DP25 2 +Copii coated vesicle budding 0.4068756311246285 0.8745552195378175 0.3818159622919643 1.0 0.8259905841251791 20 P49755,Q15363,P62820,Q9HCU5,Q9Y6B6,Q9NR31 6 +Negative regulation of bmp signaling pathway 0.5298330079427542 0.8713516203507061 0.3835621930851365 1.0 0.8277596486079639 7 P98164,Q92673 2 +Cholesterol catabolic process 0.7843330055719537 0.870058991001394 0.3842681671094521 1.0 0.8277596486079639 2 Q8WTV0 1 +Sulfur compound catabolic process 0.4929062904047703 0.8685633324988664 0.3850860175917163 1.0 0.8279856462539014 9 P16278 1 +Vasculature development 0.3255527589488309 0.8684821517884865 0.3851304389516137 1.0 0.8279856462539014 94 P52789,P55011,P09601,O95470,P04114,Q08431,O14786,Q86UE4,Q9NZ08,Q13685,P01130,P06756,P98164,Q04656,O94813,Q9Y251,P35613,P43121,Q07954,Q15363 20 +Positive regulation of immune response 0.3343640889981564 0.8660886358650806 0.386441556670074 1.0 0.8295093311057715 78 P51809,Q9NUD5,P02786,P01889,Q9NUQ9,P04439,Q06481,O15400,Q08722,P15529,P11279,Q5ZPR3 12 +Negative regulation of neuron death 0.4093636682150083 0.863458880037868 0.3878852183928027 1.0 0.8314028306686015 41 P04062,P09601,Q99538,O76024,Q01105,Q92673,P50897,P07196,Q4ZIN3,O14786 10 +Cell projection assembly 0.318463688188925 0.8629160095663095 0.3881836477098621 1.0 0.8314028306686015 86 P20339,Q16625,P05556,O00592,P62820,Q15154,A0AVF1,O14786,O00560,P42345,A6NIH7,Q04656,O94813,Q15691,Q9H223,Q9Y277,Q15555,Q4KMQ2,Q9H4M9,P11233 20 +Anatomical structure maturation 0.4103175562295698 0.8622617252814346 0.3885435097762293 1.0 0.8314028306686015 27 P04062,O75787,Q9Y2W6,O75503,P09622,P05067 6 +Epithelial cell apoptotic process 0.4625807504643848 0.8612801808858948 0.3890837485925649 1.0 0.8314028306686015 12 Q53EL6,O76024,Q4KMQ2,P09601 4 +Fatty acid derivative metabolic process 0.4036521749556265 0.8580693079995586 0.3908541937733378 1.0 0.8331156909877262 19 P50897,Q9UMR5 2 +Platelet derived growth factor receptor signaling pathway 0.4908085620429061 0.8571421489940506 0.3913663296238825 1.0 0.8331156909877262 9 Q07954,O95470 2 +Negative regulation of defense response 0.4079053058520341 0.8569121398926757 0.3914934430444132 1.0 0.8331156909877262 24 P04062,P01889,P04439,O43657,Q96J02,P01130 6 +Tube formation 0.4099902996268726 0.8563843620110629 0.3917852116518303 1.0 0.8331156909877262 28 O15031,P98164,P17612,O75386,O00592,Q15363,P49815,O60313,P11233 9 +Regulation of protein binding 0.3998567012271219 0.8553880770664628 0.3923363419910683 1.0 0.8331156909877262 50 P48681,P17612,P10586,P62942,P16615,O75955,Q07954,Q96D46,Q92673,Q9BUN8,Q9NVN8,O14786,P05067,Q15691 14 +Sterol biosynthetic process 0.4050022422258174 0.8532254404179621 0.3935342979340914 1.0 0.8331156909877262 21 Q15392,Q14739,P00387,Q15800,Q16850,P04114,P16435,Q9H2C2,Q14534 9 +Reactive oxygen species biosynthetic process 0.4718372347945599 0.8517000980882604 0.3943805661730866 1.0 0.8331156909877262 10 Q9BSK2,P51790,P00403 3 +Regulation of inflammatory response 0.4100205813146377 0.8516963489629553 0.3943826475637868 1.0 0.8331156909877262 30 P04062,P51809,P53634,Q08722,P60900,Q99735,P01130,P05067 8 +Positive regulation of intracellular protein transport 0.398098415751199 0.8514179861642953 0.3945372039726607 1.0 0.8331156909877262 51 Q92544,Q05D32,P55786,Q9NV96,Q15154,Q92673,Q9Y6B6,Q9Y282,Q9NR31,P50402,P31751 11 +Developmental cell growth 0.4048161197298791 0.850340907295384 0.3951355795557951 1.0 0.8331156909877262 45 Q15375,O94813,Q92581,Q9NQC3,P05067 5 +Germ cell migration 0.7134426229508182 0.8485356319659302 0.3961397372148096 1.0 0.8331156909877262 3 P78310,P05556 2 +Cell cell adhesion via plasma membrane adhesion molecules 0.4393719819138306 0.8483211697181109 0.3962591309813632 1.0 0.8331156909877262 15 O15031,P35613,P19022,Q9P273,P10586,P05556,Q14126,Q92692,Q14574 9 +Muscle adaptation 0.4539576438641032 0.8478174733033399 0.3965396303831472 1.0 0.8331156909877262 13 P09601 1 +Regulation of heart contraction 0.4042284630866539 0.8473724546044767 0.3967875529172231 1.0 0.8331156909877262 21 O75844,P17612,P05023,P16615,Q14126,P0DP25,P10253,P20020 8 +Regulation of lamellipodium assembly 0.438869005168373 0.8450420792387301 0.3980873453304623 1.0 0.8331156909877262 15 Q04656,Q16625 2 +Iron ion transmembrane transport 0.5785528567401551 0.8448038193348787 0.3982203818086081 1.0 0.8331156909877262 5 Q8N4V1,Q04656 2 +Paraxial mesoderm development 0.6183329973374343 0.84463943635542 0.3983121834592897 1.0 0.8331156909877262 4 Q96A65,Q12948 2 +Regulation of dendrite extension 0.7121311475409676 0.8435219234619519 0.3989366098163041 1.0 0.8331156909877262 3 O60271,Q96PU5 2 +Neutrophil degranulation 0.7774500163880838 0.8433129527573323 0.3990534405576516 1.0 0.8331156909877262 2 P51809 1 +Neutrophil activation involved in immune response 0.7774500163880838 0.8433129527573323 0.3990534405576516 1.0 0.8331156909877262 2 P51809 1 +Negative regulation of calcium ion dependent exocytosis 0.7774500163880671 0.8433129527572664 0.3990534405576884 1.0 0.8331156909877262 2 P04899 1 +Intracellular distribution of mitochondria 0.7771222549983589 0.8420439917596988 0.3997633297257765 1.0 0.8331156909877262 2 O00429 1 +Positive regulation of lipid localization 0.4458810044182288 0.8410809720685897 0.4003025740661567 1.0 0.8331156909877262 14 Q07954,P04114,Q9NV96,Q8WTV0 4 +Regulation of macrophage activation 0.5772549283370647 0.8390186879796417 0.4014588227671036 1.0 0.8331156909877262 5 P53634 1 +Mitochondrion localization 0.4295274731478514 0.8378881601280542 0.4020935189849433 1.0 0.8331156909877262 16 O75153,Q9BUK6,Q6PJG6,O00429,Q8IWA4,O60313,P07196,Q92692 8 +Positive regulation of erk1 and erk2 cascade 0.4205683172230754 0.8373631255209681 0.4023884862734719 1.0 0.8331156909877262 17 P05067,Q13641,P00533 3 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.7105031450683155 0.8373054373417502 0.4024209037145929 1.0 0.8331156909877262 3 O75844 1 +Negative regulation of mitochondrion organization 0.4451469860765789 0.8364400338611699 0.4029073986541909 1.0 0.8331156909877262 14 Q9H3K2,O60313,P02786 3 +Hyperosmotic salinity response 0.6161793915543549 0.8357820062508645 0.4032775510177924 1.0 0.8331156909877262 4 O95202 1 +Cellular response to salt stress 0.6161793915543549 0.8357820062508645 0.4032775510177924 1.0 0.8331156909877262 4 O95202 1 +Cellular hyperosmotic salinity response 0.6161793915543549 0.8357820062508645 0.4032775510177924 1.0 0.8331156909877262 4 O95202 1 +Response to axon injury 0.4202862829373561 0.8354005316200073 0.403492230602164 1.0 0.8331156909877262 17 P07196,P00374,Q96G23,P10586 4 +Regulation of erbb signaling pathway 0.4447801664909112 0.8341210596224522 0.4042127689252699 1.0 0.8331156909877262 14 Q99538,Q9NQC3,P00533 3 +T cell migration 0.5222860145682987 0.833552134924175 0.4045334076408591 1.0 0.8331156909877262 7 Q9Y624,P05067 2 +Fatty acid transmembrane transport 0.5041658572419448 0.8325621881117278 0.4050916916079694 1.0 0.8331156909877262 8 P23786,P11166,P31751 3 +Negative regulation of smooth muscle cell proliferation 0.5366607390319342 0.8317542606864495 0.4055476662589712 1.0 0.8331156909877262 6 Q53EL6,P09601 2 +Cellular response to acid chemical 0.4443520978227526 0.8314151358331957 0.4057391514413369 1.0 0.8331156909877262 14 Q6IAA8,Q9HB90,Q04656,P42345,P00533 5 +Response to platelet derived growth factor 0.4859079439716853 0.8304840512933453 0.4062651613767789 1.0 0.8331156909877262 9 Q04656 1 +Heart valve development 0.5363504495420066 0.8302557618622209 0.4063941940708246 1.0 0.8331156909877262 6 O94813 1 +Negative regulation of regulated secretory pathway 0.6147742294073147 0.8300092953866401 0.4065335281673869 1.0 0.8331156909877262 4 P04899,P09601 2 +Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.4365068768142082 0.8296473612053569 0.406738190915664 1.0 0.8331156909877262 15 P36896 1 +Cell communication by electrical coupling involved in cardiac conduction 0.6138549867033626 0.8262356853325736 0.4086704088670609 1.0 0.8331156909877262 4 P05023,P0DP25 2 +Response to estradiol 0.3991254553928999 0.824188117767665 0.4098326774675584 1.0 0.8331156909877262 19 O95831,P04114,P19021 3 +Response to acid chemical 0.4028298399214534 0.8236853516936914 0.4101183647437807 1.0 0.8331156909877262 23 Q6IAA8,Q9HB90,Q04656,P42345,P00533,O95831,P08069 7 +Positive regulation of transport 0.3717808836361502 0.822242005436674 0.4109391762540615 1.0 0.8331156909877262 160 O43633,P20339,Q16625,P55011,Q9P2W9,P05556,Q08722,Q15154,Q08431,Q9Y282,Q9NR31,Q96PU5,P51151,P19022,P17612,Q9H4A5,O00560,P50897,Q92673,P0DP25,Q9Y6B6,P20020,Q92544,Q15042,Q06481,P04899,Q05D32,P50402,P49755,P51809,P54709,Q8WUM4,P55786,Q9NV96,O75955,Q9H4M9,O00429,Q07954,Q12907,O76024,Q4KMQ2,P11279,P51149,Q96CW1,P31751 45 +Cell fate specification 0.5344374488971396 0.8210215504490965 0.4116339930770403 1.0 0.8331156909877262 6 O14786 1 +Response to increased oxygen levels 0.4833467656186677 0.8165669347800166 0.4141759574482471 1.0 0.8331156909877262 9 Q15904,Q8N511 2 +Pigment granule localization 0.6114745835494606 0.816474508100295 0.4142287975962975 1.0 0.8331156909877262 4 P62820,Q13561 2 +Middle ear morphogenesis 0.705019397945793 0.8164272597316596 0.4142558109344996 1.0 0.8331156909877262 3 P54802 1 +Cardiac chamber morphogenesis 0.454882090359288 0.8152768601184349 0.4149138511109074 1.0 0.8331156909877262 12 O14786,O94813,P98164,P16870 4 +Axon ensheathment in central nervous system 0.7699115044248014 0.8142392121869406 0.4155079258471565 1.0 0.8331156909877262 2 Q92542 1 +Leukocyte mediated immunity 0.3976262412689484 0.8127424637064826 0.416365729558493 1.0 0.8331156909877262 48 P51809,P02786,P09601,P01889,Q9NUQ9,P04439,O15400,P53634,Q07021,P15529,P11279 11 +Regulation of peptidyl threonine phosphorylation 0.4999459284346568 0.8105830238231517 0.4176051690457885 1.0 0.8331156909877262 8 P05067 1 +Locomotor rhythm 0.7034527707704146 0.8104806287666361 0.4176639940003226 1.0 0.8331156909877262 3 P54802 1 +Rhythmic behavior 0.6094626067999179 0.8082364608714785 0.4189544720777653 1.0 0.8331156909877262 4 P54802 1 +Prostate gland development 0.5700113001758519 0.8068061138541175 0.4197781961962818 1.0 0.8331156909877262 5 P07602 1 +Organic cation transport 0.5314221182448787 0.8064821923035584 0.4199648718445359 1.0 0.8331156909877262 6 Q70HW3,O43808,Q96QD8,Q9HC21 4 +Regulation of neurotransmitter levels 0.4029856987286322 0.8049156422696218 0.4208683611639863 1.0 0.8331156909877262 27 P20339,P21964,Q15042,O00186,P16615,P05556,O75955,Q7L0J3,Q5SQN1,P50897,P54920,Q13277,P0DP25,Q4J6C6 14 +Complement activation 0.608540042735527 0.8044629008776063 0.4211296868102308 1.0 0.8331156909877262 4 P15529 1 +Regulation of complement activation 0.608540042735527 0.8044629008776063 0.4211296868102308 1.0 0.8331156909877262 4 P15529 1 +Regulation of humoral immune response 0.608540042735527 0.8044629008776063 0.4211296868102308 1.0 0.8331156909877262 4 P15529 1 +Peripheral nervous system axon regeneration 0.7018466112313686 0.804392498794458 0.4211703319610587 1.0 0.8331156909877262 3 Q96G23 1 +Plasma membrane organization 0.4040643957534279 0.8042397447740339 0.4212585291731106 1.0 0.8331156909877262 30 P16615,Q4KMQ2,Q9H2C2,Q16739,P31751 5 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.4319569891979433 0.800020699981351 0.4236988040466181 1.0 0.8338595421161635 15 O95831,Q96A26,Q9NZJ7,Q9BXK5 4 +Establishment of lymphocyte polarity 0.6069368121737537 0.7979111504164418 0.4249220522149817 1.0 0.8338595421161635 4 Q14254 1 +Phenol containing compound metabolic process 0.45739434860086 0.7974036965968148 0.4252166130852006 1.0 0.8338595421161635 11 P07858,Q04656 2 +Positive regulation of smooth muscle cell proliferation 0.4797877177588068 0.7972472614453885 0.4253074427778274 1.0 0.8338595421161635 9 P08069,P04899,P09601 3 +Response to purine containing compound 0.4455246626657824 0.7960554308811267 0.4259998177218509 1.0 0.8338595421161635 13 P05067 1 +Protein localization to golgi apparatus 0.5289227610799117 0.794446416963132 0.4269355911551631 1.0 0.8341695262835989 6 P49755,Q92673 2 +Negative regulation of anion transmembrane transport 0.762372992461485 0.7854118293448604 0.4322121472969862 1.0 0.8398678269023997 2 O75915 1 +Negative regulation of anion transport 0.762372992461485 0.7854118293448604 0.4322121472969862 1.0 0.8398678269023997 2 O75915 1 +Adenylate cyclase inhibiting g protein coupled receptor signaling pathway 0.477268285228179 0.7835863303069414 0.4332828793603727 1.0 0.841208567401636 9 P04899,P07602,Q9NZJ7 3 +Regulation of platelet activation 0.6030774018658361 0.7821711870328508 0.4341139751831357 1.0 0.8416514464408867 4 Q9Y624 1 +Cellular extravasation 0.60303413573495 0.7819949953501315 0.4342175147858915 1.0 0.8416514464408867 4 Q9Y624,Q08722 2 +Axoneme assembly 0.6956367930204201 0.7809386314476442 0.4348385895380677 1.0 0.8419547547805328 3 Q15555 1 +Positive regulation of vasculature development 0.4121255792350436 0.7786773858687225 0.4361697806325952 1.0 0.8433682483278703 17 Q86UE4,P52789,P09601,Q9NZ08,O14786 5 +Negative regulation of muscle cell apoptotic process 0.5635652083860123 0.7782557672468134 0.4364182463070163 1.0 0.8433682483278703 5 P09601 1 +Tetrapyrrole metabolic process 0.3929168672653639 0.7777829459805365 0.4366969834028031 1.0 0.8433682483278703 19 P30519,Q9P0S9,P09601,Q7KZN9,O00264 5 +Myeloid cell development 0.4425381389185894 0.7777557775092075 0.4367130028465076 1.0 0.8433682483278703 13 P05067 1 +Viral life cycle 0.3211583600742654 0.7730935918168058 0.4394669933067583 1.0 0.8470030375870349 97 O43633,P20339,P05556,P62820,Q96J02,P07858,P07237,O14786,O15118,P02786,Q9H0U4,P01130,Q9H9H4,P06756,P08195,P00533,Q14108,Q16531,Q92692,Q9Y624,P35613,Q15758,Q8WTV0,Q9P035,Q8WUM4,P15529,P11279,P51149 28 +Cellular response to carbohydrate stimulus 0.402074171289098 0.7727477255233514 0.4396716958134585 1.0 0.8470030375870349 18 P62995,Q99808,P17612,Q9NWS0,P08069,Q15043,Q5KU26 7 +Positive regulation of catabolic process 0.3584151035549371 0.7723030100435412 0.4399349830600589 1.0 0.8470057754212862 146 P09601,P05141,P21796,Q969T7,Q96J02,Q4ZIN3,P05067,Q96PU5,Q86UE4,P04062,P53634,Q9BXS4,Q92673,P01130,P98164,Q15042,Q9HCE1,P27544,Q96HY6,Q13190,P12235,Q07954,Q13137,O15269,P31751 25 +Phosphatidylinositol phosphate biosynthetic process 0.5240915123298756 0.7712249129400635 0.4405736299134406 1.0 0.8474786832917178 6 Q9NX62 1 +L glutamate transmembrane transport 0.523368059837249 0.7677528773792448 0.4426340150019618 1.0 0.849404180720931 6 P05556,O75915 2 +Long chain fatty acyl coa metabolic process 0.4916624618222817 0.7675469990779058 0.4427563607035059 1.0 0.849404180720931 8 Q9NZ01 1 +Anoikis 0.4738531342195999 0.7650912022309279 0.4442172383041352 1.0 0.8501911316855318 9 Q07820,P05556,P42345 3 +Regulation of lamellipodium organization 0.4008295572428351 0.7638005435780267 0.4449861128546319 1.0 0.8501911316855318 18 Q04656,Q16625 2 +Camera type eye development 0.3995458849548336 0.7632862218166678 0.4452927172979588 1.0 0.8501911316855318 34 P48681,P54802,Q8NF37,O75569,Q9P273,Q15042,Q15293,O75386,Q15555,P00533,Q8NBN7,O14786,P20020 13 +Molting cycle 0.4262438041781401 0.7628808102277721 0.4455344815867446 1.0 0.8501911316855318 15 O75844,Q04656,P36896,Q9Y251 4 +Organic hydroxy compound metabolic process 0.3302109810573325 0.7541764266443239 0.4507432905996011 1.0 0.8543502370490433 110 P61916,P04114,P07858,P05067,Q14534,P04062,O15118,P98155,Q14849,P01130,Q13510,P98164,Q99538,P38571,Q04656,Q9H2C2,Q14739,P21964,Q8WTV0,Q9NX62,P38435,P16435,Q8NBN7,P51648,Q9BQE5 25 +Long chain fatty acyl coa biosynthetic process 0.5204317320180751 0.7536756212935447 0.4510440239287008 1.0 0.8543502370490433 6 Q9NZ01 1 +Regulation of perk mediated unfolded protein response 0.6882246633988462 0.753129202859282 0.451372277400583 1.0 0.8543502370490433 3 P57088 1 +Neural tube formation 0.394381761964462 0.7530669841034479 0.4514096630443083 1.0 0.8543502370490433 24 O15031,P98164,P17612,O75386,Q15363,P49815,O60313,P11233 8 +Regulation of aerobic respiration 0.4318049257247734 0.7522582698835234 0.4518957578722729 1.0 0.8544966834114087 14 P14406,Q9BSK2 2 +Tissue morphogenesis 0.3319213222842119 0.7505172448240451 0.4529432416288239 1.0 0.8550014094242375 76 P62942,P05556,O00592,O14786,Q15375,P17612,P42345,Q8TAA9,P10644,P98164,Q04656,Q5SZK8,P00533,O94813,P49815,O15031,O75386,Q13308,Q15363,O60313,P11233 21 +Dna catabolic process endonucleolytic 0.4880309828797163 0.7487325149037155 0.4540184419157089 1.0 0.8560318568209621 8 O00115 1 +Regulation of microtubule based movement 0.5944376444336681 0.7471098727861052 0.454997241179492 1.0 0.8573775570026606 4 P11279 1 +Positive regulation of protein catabolic process 0.3491070431758614 0.7454193302506192 0.4560182617344723 1.0 0.8575529462675295 70 Q8NF37,P04062,Q13190,P98164,P51572,P53634,O60826,Q12834,Q07954,Q9P0J0,Q92673,Q16531,Q96J02,P51149,Q4ZIN3,P01130,Q96HY6,Q96PU5 18 +Formation of primary germ layer 0.4230990598175346 0.7424735706042084 0.4578004590566245 1.0 0.8594982772209971 15 P10644,P05556,P07942,P06756 4 +Morphogenesis of an epithelium 0.3539709464917918 0.7409835526967622 0.4587034128603522 1.0 0.8602742633910408 68 Q15375,O15031,P98164,P17612,O75386,Q04656,Q5SZK8,P42345,P00533,O00592,Q8TAA9,O94813,P49815,Q13308,Q15363,O60313,O14786,P11233 18 +Cytokine production involved in immune response 0.4474170922569849 0.7395491392764165 0.4595736125863559 1.0 0.8602742633910408 11 P04439 1 +Retina homeostasis 0.5924400465907987 0.7390400229144882 0.4598826947066192 1.0 0.8602742633910408 4 Q15555,P51790 2 +Regulation of b cell proliferation 0.5032297571590432 0.7386328712211455 0.460129958269365 1.0 0.8602742633910408 7 P02786 1 +Negative regulation of multicellular organismal process 0.3210506858822977 0.7377017074362292 0.4606957343274678 1.0 0.8602742633910408 100 Q9UNN8,P55011,P09601,Q9UIQ6,P05023,P15260,Q96J02,O14786,P04062,Q15375,P53634,Q07021,Q16850,Q92673,P01130,Q9NQC3,Q99538,Q06481,P16615,Q96G23,P00533,O94813 22 +Adenylate cyclase activating g protein coupled receptor signaling pathway 0.5170778023336817 0.7376271224214369 0.4607410690783327 1.0 0.8602742633910408 6 P04899,P48960 2 +Neuron differentiation 0.3948682735339799 0.7376125723049842 0.460749913315903 1.0 0.8602742633910408 207 Q9P2K5,Q9Y6M7,Q13277,O14786,P05067,Q96PU5,P54802,P04062,Q15375,P98155,Q8NHS3,P50897,P07942,Q9NQX7,Q9NQC3,Q13641,O14949,P98164,Q06481,Q04656,Q96G23,O94813,Q9HCE1,Q14108,Q92581,O00264,Q9NZJ7,O15031,P35613,P42892,P10586,O75503,Q9NV96,O75955,Q15555,Q8NBN7,Q16739,Q9H4M9 38 +Monocyte chemotaxis 0.4857143189726671 0.7367489689229734 0.4612750216036492 1.0 0.8602742633910408 8 Q99538,O94813 2 +Neutrophil chemotaxis 0.4416563183928028 0.7365053490381842 0.4614232134986717 1.0 0.8602742633910408 12 P35613,Q07021,O94813 3 +Regulation of lipid storage 0.4514360944477473 0.7361576421759869 0.4616347666734184 1.0 0.8602742633910408 10 P04114,P06756,Q8WTV0 3 +I kappab kinase nf kappab signaling 0.3831335025260863 0.7359748946122596 0.4617459763767679 1.0 0.8602742633910408 53 Q86UE4,Q13501,P02786,P09601,Q8TB61,O43657,Q8IUH4,Q8WVQ1 8 +Response to calcium ion 0.3894697861255848 0.7359621041020136 0.4617537605090611 1.0 0.8602742633910408 21 Q99538,Q92542,P0DP25 3 +Voluntary musculoskeletal movement 0.6831346203734963 0.7341567586024844 0.4628532042777316 1.0 0.8602742633910408 3 P42345 1 +Mitochondrial electron transport nadh to ubiquinone 0.390384596243605 0.7287614424142868 0.466147601058704 1.0 0.8633005528911412 23 P09622,O96000,Q9Y6M9,O43676,P03886,O75438,P03915 7 +Protein import 0.3063390971154352 0.7285017771000679 0.4663064812149087 1.0 0.863347632220734 83 Q9NS69,Q13501,P40855,O60830,Q06481,O14925,O95831,Q99595,Q96P70 9 +Regulation of response to endoplasmic reticulum stress 0.3883823802201951 0.72777759877458 0.4667497394849405 1.0 0.8636739315583752 21 O95881,O76024,O60313,Q4ZIN3,Q96HY6 5 +Head development 0.357919873033849 0.7273162944711687 0.4670322185050726 1.0 0.8638018806027064 150 O94901,O75569,Q96QD8,Q96N66,P05556,Q9BRK5,O95470,Q15154,O14786,P05067,P48681,P54802,Q15375,P04062,P19022,P35610,P08069,O15511,P50897,P0DP25,Q9Y320,Q9UID3,P07942,Q9NQC3,P20020,O14949,Q9BXW9,Q9UQB8,P98164,O75787,Q15042,Q04656,Q92542,P00533,O94813,P61421,O15031,O75503,O75386,P07196,P08754,P11166,Q5KU26 43 +Artery morphogenesis 0.4498490784943056 0.727208719306276 0.467098105632119 1.0 0.8638018806027064 10 Q07954,P04114,P01130 3 +B cell differentiation 0.4492046665159003 0.7235770430516975 0.4693254394899671 1.0 0.8659600755955899 10 Q5HYI8,P05141 2 +Exocrine system development 0.5508411812658407 0.722272917284768 0.4701267003282954 1.0 0.8659600755955899 5 P00533 1 +Biological adhesion 0.374278159831833 0.7220638863775406 0.4702552001052644 1.0 0.8659600755955899 175 Q08722,Q14126,O00592,P62820,Q08431,Q96J02,Q13277,P07237,O14786,P05067,Q5ZPR3,Q15375,Q08380,P19022,P02786,Q07021,P07942,Q9UM22,Q13641,P10644,Q92544,P06756,Q96JJ3,Q9NUQ9,P16615,Q5SZK8,P30825,P00533,Q14574,Q9Y251,Q9Y624,O15031,P35613,P48960,P10586,Q8WTV0,P04439,O75955,P43121,P15529,Q96J84,P14543 42 +Positive regulation of peptidyl serine phosphorylation 0.3852112528921866 0.720340139923948 0.4713155961959698 1.0 0.8659600755955899 19 P02786,P05067,P00533 3 +Response to l glutamate 0.5502754801600093 0.719796764273211 0.4716501374627366 1.0 0.8662989038178431 5 P08069,O95831 2 +G protein coupled receptor signaling pathway 0.3900458757853136 0.7189687400950273 0.4721601805546851 1.0 0.8667435323519461 45 P42892,P16870,P48960,Q99720,Q06481,Q99523,P11717,P07602,Q92673,P0DP25,Q9NZJ7 11 +Vascular associated smooth muscle cell migration 0.5872456466866365 0.7181249316409104 0.4726802588530807 1.0 0.8668339219353655 4 Q04656 1 +Positive regulation of wound healing 0.4476807532598057 0.71499371958426 0.4746129240535133 1.0 0.8692726516710582 10 P05556,Q4KMQ2,Q16625,Q9Y251 4 +Protein targeting to peroxisome 0.5863301212808922 0.7144493142570982 0.4749493874190587 1.0 0.8696426796529553 4 O75381,P40855 2 +Negative regulation of ion transport 0.4027224533559105 0.7135342640368987 0.4755152184162048 1.0 0.8699400305244426 17 P62942,Q04656,P0DP25,P21796,Q96PU5 5 +Protein import into peroxisome membrane 0.7423795476893047 0.7102871646182692 0.4775260776482675 1.0 0.8718928016672396 2 P40855 1 +Protein import into peroxisome matrix 0.7423795476892787 0.7102871646181725 0.4775260776483274 1.0 0.8718928016672396 2 O75381 1 +Sensory system development 0.39152685309876 0.709909501092 0.4777602582172997 1.0 0.8720742410856975 41 P48681,P54802,Q8NF37,O75569,Q9P273,Q15042,Q15293,O75386,Q5SZK8,Q15555,Q16706,P00533,Q8NBN7,Q9NP72,O14786,P20020 16 +Myeloid cell activation involved in immune response 0.4803893380488686 0.709265574691904 0.4781596871408333 1.0 0.8722014031180816 8 P09601 1 +Regulation of b cell mediated immunity 0.4312785574632219 0.7089695143244897 0.4783433952577698 1.0 0.8722014031180816 13 P15529,P02786 2 +Neural precursor cell proliferation 0.3906543450917416 0.7087106372673012 0.4785040624000729 1.0 0.8722014031180816 27 P48681,Q9H0H5,O15031,P19022,P98164,Q06481,Q15154,P55209 8 +Nucleoside bisphosphate biosynthetic process 0.3892523750454276 0.7079559277167674 0.4789726268177516 1.0 0.8724270444366188 25 P09622,Q8TB61,P50897,Q9UMR5 4 +Positive regulation of receptor catabolic process 0.7417240249098889 0.707859614701484 0.4790324411561091 1.0 0.8724270444366188 2 Q96J02 1 +Vesicle cargo loading 0.4415789895297334 0.7058182063213254 0.4803011984210403 1.0 0.8735668814123928 11 Q15363,P62820,Q9NR31 3 +Porphyrin containing compound metabolic process 0.4173394565935712 0.7051780173429716 0.4806994596950735 1.0 0.8735668814123928 15 O00264,P30519,P09601,Q7KZN9 4 +Negative regulation of ion transmembrane transport 0.4094875461795126 0.7034906239473929 0.4817500478330196 1.0 0.8735668814123928 16 P62942,Q04656,P0DP25,P21796,Q96PU5 5 +C4 dicarboxylate transport 0.479030782567432 0.7022684924605954 0.4825117384911555 1.0 0.8735668814123928 8 Q9UBX3,P55011 2 +Regionalization 0.3884879853979657 0.7020801836189191 0.4826291597106031 1.0 0.8735668814123928 25 P98164,O75787,Q9Y2W6,O75386,Q15363,O14786 6 +Regulation of transmembrane transport 0.3498105864244914 0.6939928454726038 0.4876866957147916 1.0 0.8780689802061846 68 P54709,P52789,O75844,Q16625,P62942,Q06481,P05556,Q04656,O75915,P0DP25,Q4KMQ2,P31751,P21796,P05067,Q96PU5 15 +Calcium ion regulated exocytosis 0.4439056924482694 0.6937624706962044 0.4878311817685929 1.0 0.8780689802061846 10 P16615,Q9BRK5,Q15042 3 +Epoxide metabolic process 0.7374631268436541 0.6921395845577879 0.4888496748441824 1.0 0.8784917889158889 2 P34913 1 +Very long chain fatty acid metabolic process 0.443216370857383 0.6898907945032328 0.4902628652665621 1.0 0.8784917889158889 10 Q9P035,Q15067,O14678,P50542,Q9NZ01 5 +Regulation of myeloid leukocyte mediated immunity 0.4763890345820809 0.6886808612667494 0.491024122712127 1.0 0.8784917889158889 8 P09601 1 +Negative regulation of anoikis 0.5797301256094981 0.6880521627946049 0.4914199334555842 1.0 0.8786249606405222 4 P05556 1 +Negative regulation of smoothened signaling pathway 0.5794555682161824 0.6869579909407114 0.4921092013860257 1.0 0.8786249606405222 4 O75386 1 +Dna catabolic process 0.4592658032089102 0.6864520663807011 0.4924280812120272 1.0 0.8786249606405222 9 O00115 1 +Regulation of reactive oxygen species biosynthetic process 0.475652861061848 0.6848988881811304 0.4934077276470399 1.0 0.8787513456668725 8 P51790,Q9BSK2 2 +Negative regulation of lipid metabolic process 0.4418450128526012 0.682193322280126 0.495116716603011 1.0 0.880162143364902 10 Q92673 1 +Intracellular lipid transport 0.4264352139536175 0.679506162344735 0.496817204401061 1.0 0.8810061664666842 13 O15118,P01130,P61916,Q9H2C2 4 +Xenophagy 0.5766754573425499 0.675897069430204 0.4991059984996391 1.0 0.8834575492294403 4 Q13137 1 +Central nervous system development 0.3796341521260643 0.675761299162226 0.4991922097216674 1.0 0.8834575492294403 189 O94901,O75569,Q96QD8,Q96N66,P05556,Q9BRK5,Q15154,P15260,O14786,P05067,P48681,P54802,Q15375,P04062,P19022,P98155,P42345,P35610,P08069,O15511,P50897,P0DP25,Q9Y320,Q9UID3,P07942,Q9NQC3,P19021,P01130,P20020,O14949,Q9BXW9,P98164,O75787,Q15042,Q06481,Q04656,Q92542,P00533,O94813,O15031,O75503,O75386,P07196,Q07954,O14773,Q86XL3,P11166,P51648,Q5KU26 49 +Alpha beta t cell activation 0.4122478956835648 0.6723105100185102 0.5013860402562254 1.0 0.8849839821057358 15 P04439,Q04656 2 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.3882357782169938 0.6710530703323028 0.5021867218323788 1.0 0.885538531158456 34 P01889,P02786,Q9NUQ9,P04439,O15400,P53634,Q07021,P15529 8 +Regulation of actin cytoskeleton reorganization 0.4397026116966684 0.6701816831434422 0.5027419789096212 1.0 0.885538531158456 10 Q9Y624,Q9UQB8,Q9Y5K6,Q9NRX4,O14786 5 +Positive regulation of actin cytoskeleton reorganization 0.5748481886890171 0.6686457527338723 0.5037214794965892 1.0 0.8858169234196581 4 O14786 1 +Negative regulation of gtpase activity 0.4886718336126944 0.6668326669547407 0.5048790240407268 1.0 0.8860722752358823 7 Q9Y624 1 +Regulation of calcium mediated signaling 0.5020183336873927 0.6660352178637343 0.5053885901154724 1.0 0.8864880729431815 6 P0DP25 1 +Cellular response to starvation 0.3874411045050774 0.6656266756885817 0.5056497514539839 1.0 0.8864880729431815 33 P04062,Q96QD8,P56192,P21964,Q9Y4P8,Q9HB90,P42345,P11166,Q9Y4P3 9 +Chemical synaptic transmission postsynaptic 0.4240740587354758 0.6651756369751745 0.5059381612778213 1.0 0.8864880729431815 13 Q9UQB8,P05067,Q15042 3 +Regulation of postsynaptic membrane potential 0.4240740587354758 0.6651756369751745 0.5059381612778213 1.0 0.8864880729431815 13 Q9UQB8,P05067,Q15042 3 +Fatty acyl coa metabolic process 0.4174828134061206 0.6624534768985434 0.5076806411328261 1.0 0.8873780241794791 14 Q9UMR5 1 +T cell differentiation involved in immune response 0.500465049175269 0.6587002086012675 0.510088299011237 1.0 0.8899032379459796 6 P15529,Q04656 2 +Cardiac muscle cell membrane repolarization 0.5354473833611137 0.6553414407008451 0.512247945203977 1.0 0.8915071179780809 5 O75844 1 +Lipophagy 0.5347915511027592 0.6525122612656595 0.5140707656745263 1.0 0.8934776418991162 5 O15269 1 +Cellular modified amino acid catabolic process 0.4990329227328977 0.6519463940058764 0.5144357544566205 1.0 0.8936318194360575 6 Q9UHG3 1 +Organelle transport along microtubule 0.3837380859500667 0.6504329314457615 0.5154126111830335 1.0 0.8945172240302388 28 Q92572,O94901,Q5SNT2,P62820,O60313,P07196,P11279 7 +Morphogenesis of embryonic epithelium 0.3829635510726455 0.6489797323732748 0.5163514765593606 1.0 0.8945172240302388 27 O15031,P98164,P17612,O75386,Q15363,P49815,O60313,P11233 8 +Regulation of superoxide metabolic process 0.5336358074555073 0.6475313419260945 0.5172881167044392 1.0 0.8946571388419792 5 P04899,P00374 2 +Regulation of transforming growth factor beta1 production 0.7250081940347664 0.6468044890369072 0.5177584866874656 1.0 0.8946571388419792 2 O75787 1 +Transforming growth factor beta1 production 0.7250081940347664 0.6468044890369072 0.5177584866874656 1.0 0.8946571388419792 2 O75787 1 +Regulation of rho protein signal transduction 0.4148002908983519 0.6457236217645981 0.5184583597869334 1.0 0.8946571388419792 14 Q9Y624,O75955,O14786 3 +Cellular response to peptide hormone stimulus 0.3502083503140926 0.6450709401813808 0.518881214732009 1.0 0.8946571388419792 66 Q92572,P56192,Q9UQB8,Q06481,P14672,P08069,P04899,P16435,P49815,Q92673,Q9BSK2,Q15043,O14654,P31751,P20020,P43490 16 +Regulation of protein autophosphorylation 0.4678581932893831 0.644984824819379 0.5189370198719372 1.0 0.8946571388419792 8 Q15375 1 +Peptidyl threonine modification 0.3839802387446107 0.6448310565386773 0.5190366736858785 1.0 0.8946571388419792 30 Q10472,P36896,P05067,P0DP25 4 +Developmental growth 0.3151194120079492 0.6439557939037605 0.5196041001605811 1.0 0.8949922972929657 101 P10644,Q15375,O75844,Q99538,O95470,Q15363,O94813,P16435,P07602,Q92581,Q9NQC3,P05067,Q96PU5,Q9NZJ7 14 +Regulation of phospholipid catabolic process 0.5684229217564041 0.6432703908804565 0.5200486653713021 1.0 0.8949922972929657 4 P01130 1 +Protein n linked glycosylation 0.3837094180491863 0.6413143839065698 0.5213184457244573 1.0 0.8952506040327884 18 Q9HC07,Q9BV10,Q9BT22,P26572,Q2TAA5,P46977 6 +Regulation of vesicle size 0.6568073613028947 0.6378744520519006 0.5235554095418145 1.0 0.8974244685548483 3 P20339 1 +Positive regulation of epithelial to mesenchymal transition 0.4959722546175256 0.6375426218611767 0.5237714565295686 1.0 0.8975569674939813 6 Q12948,O00560,P42345 3 +Cell killing 0.3749798920878148 0.6356606331592065 0.524997640374619 1.0 0.8989438156652754 20 P01889,Q9NUQ9,P04439,O15400,P53634,P11279 6 +Cellular component maintenance 0.4189978254961525 0.6344488251321317 0.5257879542023898 1.0 0.8993872864192196 13 Q9BRK5 1 +Regulation of nervous system process 0.4243662849465356 0.6343283004179334 0.5258665909448619 1.0 0.8993872864192196 12 P53634,P05067 2 +Positive regulation of protein containing complex disassembly 0.4656812154415494 0.6338828057770327 0.526157307551878 1.0 0.8993872864192196 8 P48681,P04062,Q13137 3 +Regulation of glucocorticoid metabolic process 0.720419534578848 0.6303470066392529 0.5284675744207108 1.0 0.900831815264184 2 P05023 1 +Oogenesis 0.4234142058057536 0.6287376472303303 0.5295208269556682 1.0 0.90213230345107 12 P07686 1 +Homophilic cell adhesion via plasma membrane adhesion molecules 0.4281240695333015 0.6285421219479255 0.5296488620354249 1.0 0.90213230345107 11 O15031,P35613,P19022,Q9P273,P05556,Q14126,Q92692,Q14574 8 +Regulation of mitochondrial gene expression 0.4482994840572408 0.6278288239313956 0.5301160816663599 1.0 0.9026904270333462 9 Q567V2,Q9Y2R0 2 +Negative regulation of blood circulation 0.6532569548846319 0.6251549455433337 0.5318693688625833 1.0 0.904596824073064 3 P16615 1 +Cardiac conduction 0.4047972219891803 0.6244243951715837 0.5323489081147956 1.0 0.904609437058724 15 O75844,P17612,P16615,P05023,Q14126,P0DP25,P20020 7 +Glycolytic process through fructose 6 phosphate 0.4474835256818528 0.6234876591842475 0.5329641094212751 1.0 0.9048027037301636 9 Q9BRR6 1 +Negative regulation of protein localization to cell surface 0.5633505017482956 0.6233798260332782 0.5330349519115247 1.0 0.9048027037301636 4 Q96PU5 1 +Dna templated transcription termination 0.4796309367522685 0.6226588858234346 0.5335087059506947 1.0 0.9053218646545068 7 O75844 1 +Protein localization to endoplasmic reticulum exit site 0.5628074778615754 0.6212582252653822 0.5344297350271956 1.0 0.9058321760768412 4 P51572,Q5JRA6,Q92538 3 +Detection of muscle stretch 0.6521291481546541 0.6211289673608235 0.5345147712718687 1.0 0.9058321760768412 3 P19022 1 +Mitochondrion distribution 0.5626855836611862 0.6207821940802525 0.5347429403497901 1.0 0.9058321760768412 4 O75153,O00429 2 +Ear development 0.3768734418200242 0.6195021746100488 0.5355855897775563 1.0 0.9063940394563672 24 P54802,P42892,P39210,Q5SZK8,Q9Y6M7 5 +Cellular response to nitrogen compound 0.3399764252733127 0.618254980947857 0.5364072726301004 1.0 0.9071944174232992 136 Q6IAA8,Q15043,Q9NUD5,O14654,P05067,Q92572,P56192,P17612,P42345,P14672,P08069,O95831,Q92673,P20020,Q9UQB8,Q99538,Q06481,Q04656,Q92542,P00533,P04899,O94813,P49815,Q9BSK2,Q9HB90,O75955,P08754,Q07954,P16435,Q5KU26,P31751,P43490 32 +Positive regulation of mitochondrial fission 0.4786333873935374 0.6178075632323063 0.5367021972979487 1.0 0.907218843564262 7 P11233 1 +Regulation of viral entry into host cell 0.4916074090998713 0.6170758986128075 0.5371846648779897 1.0 0.9073140636295884 6 P07237 1 +Positive regulation of protein dephosphorylation 0.4036054174459819 0.6167910106771327 0.5373725820133521 1.0 0.9073140636295884 15 P04062,Q86XL3 2 +Positive regulation of dephosphorylation 0.4036054174459819 0.6167910106771327 0.5373725820133521 1.0 0.9073140636295884 15 P04062,Q86XL3 2 +Response to progesterone 0.6507749326840279 0.6163041346916638 0.53769381048744 1.0 0.9074490510355724 3 Q969T9 1 +Notch signaling pathway 0.3963086605695226 0.6158998836734038 0.5379605983492688 1.0 0.9074490510355724 16 P05067,Q92542 2 +Positive regulation of canonical wnt signaling pathway 0.370919565206304 0.6144910120541769 0.5388909105870494 1.0 0.908000781669114 19 Q9P0T7,O75787,Q96K76,P00533,Q9BZK7 5 +Response to bmp 0.379421557630101 0.6108645528748967 0.5412892534186995 1.0 0.909909103435137 18 Q05D32,P98164,O00400,Q92673 4 +Membrane raft organization 0.4447187093302288 0.6088016016563907 0.5426559518577019 1.0 0.9100871682307085 9 O75955,O15118,P50897 3 +Tissue remodeling 0.3874105005874709 0.6082388505117232 0.5430290709757937 1.0 0.9100871682307085 17 P02786,Q92791,P38571,Q04656,O14773 5 +Endosome to lysosome transport 0.3871928375172289 0.6067512392560288 0.5440160121161566 1.0 0.9100871682307085 17 P51809,Q99523,P20645,P51149,Q9UNK0 5 +Specification of symmetry 0.558822293816947 0.6057356958294804 0.5446902764313135 1.0 0.9100871682307085 4 Q10567,Q15363 2 +Bone development 0.37658914726934 0.6050897257242377 0.545119380548615 1.0 0.9100871682307085 26 O75844,Q92896,Q7RTS9,Q9NX62,Q15904,P16435 6 +Regulation of cytokinesis 0.3730556038486197 0.6050568179188467 0.5451412449911932 1.0 0.9100871682307085 22 Q9H0H5,P08069,P41208,P0DP25,Q16513 5 +Paraxial mesoderm formation 0.7132087840052397 0.6047689773517261 0.5453325091645025 1.0 0.9100871682307085 2 Q96A65 1 +Paraxial mesoderm morphogenesis 0.7132087840052397 0.6047689773517261 0.5453325091645025 1.0 0.9100871682307085 2 Q96A65 1 +Mesenchyme morphogenesis 0.7132087840052397 0.6047689773517261 0.5453325091645025 1.0 0.9100871682307085 2 Q96A65 1 +Negative regulation of proteolysis 0.3463994189231953 0.6031370558313596 0.5464175169050536 1.0 0.9100871682307085 66 Q06481,Q92896,Q07954,Q9BXS4,Q92673,Q86UE8,P07858,P05067 8 +Regulation of neural precursor cell proliferation 0.4013961320454388 0.6026620477638035 0.5467335340583861 1.0 0.9100871682307085 15 P48681,P98164,P19022,Q06481,P55209 5 +Artery development 0.4078418303544552 0.6024934883808283 0.5468456963407478 1.0 0.9100871682307085 14 Q07954,P04114,P01130 3 +Regulation of striated muscle cell differentiation 0.4594417077175502 0.6021856218369777 0.5470505853808694 1.0 0.9100871682307085 8 Q9BYT8,P42345,P11413,Q13547,P49840,Q15014,O94826 7 +Lamellipodium assembly 0.369072634035868 0.600899582997866 0.5479068709745252 1.0 0.9106910453068352 19 Q04656,Q16625 2 +Positive regulation of synaptic vesicle recycling 0.7118977384464067 0.6001569345174239 0.5484016515400065 1.0 0.9109878350106212 2 Q96CW1 1 +Cellular response to leucine starvation 0.6461943116835704 0.6000615043111545 0.5484652467571518 1.0 0.9109878350106212 3 P42345 1 +Membrane biogenesis 0.3751271686501106 0.5998343370932 0.5486166468995379 1.0 0.9109878350106212 25 P19022,O75955,Q9NRX5,Q86XL3,Q16739 5 +Negative regulation of release of cytochrome c from mitochondria 0.4878563400262201 0.5995616236780643 0.548798429467968 1.0 0.9109878350106212 6 Q9H3K2 1 +Diol biosynthetic process 0.4586923964040928 0.5983920209728735 0.5495783885004748 1.0 0.9111218556153566 8 Q13510,P04062,O15269 3 +Diol metabolic process 0.4586923964040928 0.5983920209728735 0.5495783885004748 1.0 0.9111218556153566 8 Q13510,P04062,O15269 3 +Positive regulation of phospholipase activity 0.4582035366661332 0.5959185978291407 0.5512296083721282 1.0 0.9116896412084898 8 P40616,Q14344,P00533,Q9Y263,P18085 5 +Basement membrane organization 0.4581749229708773 0.5957738633022118 0.5513263064473044 1.0 0.9116896412084898 8 P07942,P14543 2 +Bile acid metabolic process 0.4262179590353483 0.5950222490094671 0.5518285988840048 1.0 0.91228704476888 10 Q9H2C2 1 +Regulation of sterol transport 0.4579058187712113 0.5944128836497354 0.5522359934507151 1.0 0.9124941613365712 8 Q07954,Q9H2C2 2 +Renal water homeostasis 0.6442879174630354 0.5933375077180734 0.5529553019446685 1.0 0.9126717966857204 3 O76024 1 +Positive regulation of cysteine type endopeptidase activity 0.378138155363339 0.5928581085682165 0.5532761153572099 1.0 0.9128138715240476 32 Q9NR28,Q9BXK5,Q99538,Q96A26,O95831,Q9P0J0,Q9NZJ7 7 +Regulation of dna damage response signal transduction by p53 class mediator 0.4217466894420173 0.5921967454644881 0.5537188485316413 1.0 0.9131297244983654 11 Q9UNS2,O75844 2 +Tube development 0.3402305058187197 0.5920949811205461 0.5537869875545156 1.0 0.9131297244983654 139 P52789,P55011,P09601,O95470,P04114,O00592,P04920,Q08431,O14786,Q86UE4,Q15375,Q9NZ08,Q13685,P01130,P06756,P98164,O75787,P38571,Q04656,P00533,O94813,Q9Y251,O15031,P35613,P42892,P43121,Q07954,Q15363,O60313,P11233 30 +Fatty acyl coa biosynthetic process 0.421701439117246 0.591939615401358 0.553891024722768 1.0 0.9131297244983654 11 Q9UMR5 1 +Sympathetic ganglion development 0.7066535562111004 0.5818313405548584 0.5606802915293048 1.0 0.9159843401357404 2 O14786 1 +Cranial ganglion development 0.7066535562111004 0.5818313405548584 0.5606802915293048 1.0 0.9159843401357404 2 O14786 1 +Dorsal root ganglion development 0.7066535562111004 0.5818313405548584 0.5606802915293048 1.0 0.9159843401357404 2 O14786 1 +Synaptic vesicle clustering 0.7066535562111 0.5818313405548567 0.5606802915293059 1.0 0.9159843401357404 2 P19022 1 +Male genitalia development 0.7066535562110917 0.5818313405548281 0.5606802915293252 1.0 0.9159843401357404 2 Q15392 1 +Lung associated mesenchyme development 0.7066535562110752 0.5818313405547707 0.5606802915293638 1.0 0.9159843401357404 2 Q13308 1 +Regulation of core promoter binding 0.7066535562110738 0.5818313405547662 0.5606802915293669 1.0 0.9159843401357404 2 Q12948 1 +Extracellular matrix assembly 0.4711639599639824 0.5816405873917899 0.5608087981637289 1.0 0.9159843401357404 7 Q04656 1 +Establishment of endothelial barrier 0.3834382300664287 0.5811392905093973 0.5611465799266351 1.0 0.9159843401357404 17 Q9Y624,P62820,Q9Y251 3 +Lens fiber cell development 0.7063257948213655 0.5806926124915855 0.5614476415544789 1.0 0.9159843401357404 2 P08670 1 +Lens fiber cell differentiation 0.7063257948213655 0.5806926124915855 0.5614476415544789 1.0 0.9159843401357404 2 P08670 1 +Positive regulation of protein phosphorylation 0.3136224756556225 0.5788336671885063 0.5627014117749398 1.0 0.9166747501314748 105 Q15375,Q13501,P02786,Q9H223,P98155,O75955,O00560,P00533,P0DP25,Q99627,Q96HY6,P05067,P31751 13 +Mesoderm morphogenesis 0.4547297389219925 0.5783793368683566 0.5630080413460989 1.0 0.9167125646785588 8 P10644,P05556 2 +Ventricular cardiac muscle tissue development 0.4702668952037039 0.5773168365397378 0.5637254421032136 1.0 0.917496610204523 7 O75844,P98164 2 +Folic acid metabolic process 0.4701805873362743 0.5769010772259849 0.5640062828548715 1.0 0.917496610204523 7 Q9H2D1 1 +Fat cell differentiation 0.374822930512915 0.5766800901402004 0.5641555845743973 1.0 0.917496610204523 29 P14672,Q99523,Q9BRK5,P31751 4 +Endodermal cell differentiation 0.46967626268287 0.5744724926182397 0.5656481095616841 1.0 0.917759589064862 7 P06756 1 +Endoderm formation 0.46967626268287 0.5744724926182397 0.5656481095616841 1.0 0.917759589064862 7 P06756 1 +Response to amino acid starvation 0.4028912980383854 0.571904510076543 0.5673866684087385 1.0 0.917759589064862 14 Q9HB90,Q96QD8 2 +Cellular respiration 0.3113868044340986 0.5697867285154725 0.5688223579755773 1.0 0.917759589064862 103 O75964,P14406,Q7KZN9,Q15070,Q9Y6M9,Q15526,P04062,Q9UDW1,P03886,O75438,P03915,O14949,Q9NZ45,Q13423,Q04656,O96000,P00403,O43676,O95169,Q9BSK2,Q9H3K2,P09622,P13073 23 +Chromosome organization involved in meiotic cell cycle 0.3891618805841202 0.5688031468842789 0.5694897388387155 1.0 0.917759589064862 16 Q92791,Q9BTX1,Q9BXW9 3 +Protection from non homologous end joining at telomere 0.5488734947441861 0.5673702362749645 0.5704626671394628 1.0 0.917759589064862 4 Q92889 1 +Vesicle mediated transport to the plasma membrane 0.3734452155863614 0.5666707302022915 0.5709379104924079 1.0 0.917759589064862 44 Q9BZG1,Q9H223,Q9H4A5,Q96L92,O60826,Q15904,P51149,Q9UID3,Q92673,Q9H4M9,Q13277,Q4J6C6 12 +Cellular component morphogenesis 0.3317699319437162 0.5658493917219887 0.5714961670863772 1.0 0.917759589064862 130 P05556,O14786,P05067,Q96PU5,P48681,Q15375,P19022,P98155,P08069,Q9NQC3,Q13641,P10644,P98164,Q06481,Q04656,O94813,Q9HCE1,Q92581,O00264,Q92692,O15031,P35613,P42892,O75955,P07196,Q16527 26 +Cellular defense response 0.6361566779973699 0.5649054036788113 0.5721381080362822 1.0 0.917759589064862 3 Q08380 1 +Negative regulation of cell activation 0.3727655223480829 0.5638399449513163 0.572863064115632 1.0 0.917759589064862 18 P10644,P01130,P09601 3 +Lipopolysaccharide mediated signaling pathway 0.4361774788693724 0.5636832802738709 0.5729696981547994 1.0 0.917759589064862 9 Q86UE4 1 +Calcium ion transport into cytosol 0.4070798815746239 0.5628322984478531 0.5735490846231259 1.0 0.917759589064862 13 P62942,O95202,P0DP25 3 +Establishment of protein localization to organelle 0.3611932317662961 0.5620990132121488 0.5740485606416115 1.0 0.917759589064862 173 Q9NS69,P52789,Q13501,Q8N4H5,O60830,Q15070,Q99595,Q96P70,Q9Y5M8,P40855,O14925,O95831,Q9H1Z9,Q92673,P0DP25,P20645,P33908,Q15042,Q06481,Q99523,Q15005,Q14108,Q15629,P55786,P11279,P11233 26 +Ether metabolic process 0.4512315270935827 0.5607847462832533 0.5749442865197172 1.0 0.917759589064862 8 P07099,Q6IAN0,O00116,P34913,P43034,Q8WVX9,O15228 7 +Regulation of morphogenesis of an epithelium 0.7000983284169076 0.559209022651744 0.5760190761357147 1.0 0.917759589064862 2 P35222 1 +Negative regulation of response to endoplasmic reticulum stress 0.4064445347334612 0.5590381611609379 0.576135676486691 1.0 0.917759589064862 13 O76024,Q96HY6,O60313 3 +Positive regulation of coagulation 0.6339934064680703 0.5574110087098237 0.5772466456476888 1.0 0.9185864171206526 3 Q9Y251 1 +Protein deglycosylation 0.4787288635222826 0.5572587507549578 0.5773506542610549 1.0 0.9185864171206526 6 P33908,O00754 2 +Regulation of dna binding transcription factor activity 0.3417764115969424 0.5523013081235583 0.580741934518787 1.0 0.9198872611170502 66 Q86UE4,P02786,P09601,O75955,Q86VP1,P60900,Q14254,O76024,Q96J02,Q96HY6,P05067 11 +Regulation of presynaptic cytosolic calcium ion concentration 0.6978039986889759 0.5513684634645332 0.5813811147344854 1.0 0.9205783105099948 2 P20020 1 +Substrate adhesion dependent cell spreading 0.3677138324259856 0.5503222569363801 0.5820983610952304 1.0 0.9209083633957068 24 P06756,P62820,P07942,P07237,O14786 5 +Animal organ regeneration 0.3992000583781196 0.549198939167827 0.5828689323520679 1.0 0.9210012514375984 14 P11717 1 +Positive regulation of atp metabolic process 0.5096719607363634 0.5458110973385142 0.5851957942389259 1.0 0.9218750430103312 5 P05067 1 +Positive regulation of nucleotide metabolic process 0.5096719607363634 0.5458110973385142 0.5851957942389259 1.0 0.9218750430103312 5 P05067 1 +Non canonical wnt signaling pathway 0.4762159116566469 0.545696600017781 0.5852745094517591 1.0 0.9218750430103312 6 Q8TAA9 1 +Estrogen biosynthetic process 0.6945263847918826 0.5402391206435703 0.5890321368744407 1.0 0.9240320122465164 2 Q53GQ0 1 +Protein localization to microtubule organizing center 0.4316569744390942 0.5399738981767168 0.5892150333153316 1.0 0.9240320122465164 9 Q14789,Q15154,Q13561 3 +Multicellular organismal signaling 0.3641825521171775 0.5389575255745194 0.5899161625902583 1.0 0.924644241969876 22 P04062,O75844,P17612,P05023,P16615,P42345,Q14126,P0DP25,P20020 9 +Positive regulation of organelle assembly 0.3666431655676861 0.5355019358428501 0.5923028193315618 1.0 0.924976575658006 25 Q9P2W9,O00560,Q15555 3 +Positive regulation of lipase activity 0.4307680846790339 0.5353268634659002 0.5924238536135589 1.0 0.924976575658006 9 P40616,Q14344,P00533,Q9Y263,P18085 5 +Dendrite morphogenesis 0.3687469974779915 0.5342152344544606 0.5931926301746437 1.0 0.9256657061018544 28 P98155,P05556,O14786,Q13641,Q96PU5 5 +Segmentation 0.4022596971492899 0.5341153758662015 0.5932617123973238 1.0 0.9256657061018544 13 Q15363,Q9Y2W6 2 +Fatty acid alpha oxidation 0.6268878078536724 0.5330108656520759 0.5940260587897424 1.0 0.9258423192266344 3 A1L0T0 1 +Regulation of canonical wnt signaling pathway 0.3713423445878623 0.5330016437586063 0.5940324424471566 1.0 0.9258423192266344 35 Q9P0T7,P50402,P19022,O75787,Q96K76,P00533,Q9BZK7,Q13641 8 +Glial cell differentiation 0.3699221615425051 0.5316721846722663 0.594953060034991 1.0 0.926293945936548 43 Q92542,Q07954,P15260,P01130,P05067,P31751 6 +Mononuclear cell differentiation 0.3699908775015115 0.5287067843439933 0.5970088701370431 1.0 0.92790948381957 42 P04062,Q9BXW9,P24390,P01889,P05556,P05141,Q04656,Q5HYI8,P15529,O96005 10 +Negative regulation of ryanodine sensitive calcium release channel activity 0.5382521379929776 0.5270738558183551 0.598142301364601 1.0 0.92790948381957 4 P0DP25 1 +Positive regulation of sequestering of calcium ion 0.5382521379929776 0.5270738558183551 0.598142301364601 1.0 0.92790948381957 4 P0DP25 1 +Negative regulation of calcium ion transport into cytosol 0.5382521379929774 0.5270738558183544 0.5981423013646014 1.0 0.92790948381957 4 P0DP25 1 +Apical protein localization 0.5375632968920953 0.5244858365829108 0.5999406683652313 1.0 0.9298074230126212 4 Q9HD26,P54920 2 +Protein folding in endoplasmic reticulum 0.4282100703628193 0.5219827605967071 0.601682333730901 1.0 0.9301421480954966 9 P07237 1 +Peptidyl tyrosine autophosphorylation 0.6235316511977069 0.5216052819475459 0.6019451849463295 1.0 0.9301421480954966 3 P00533 1 +Axon extension 0.366152557431314 0.5196322682194908 0.6033199031393883 1.0 0.9301421480954966 27 O94813,O14786,Q92581,Q9NQC3 4 +Regulation of vascular endothelial growth factor receptor signaling pathway 0.6869878728285754 0.5149702404119071 0.6065738158902902 1.0 0.9312091667295992 2 P18031 1 +Negative regulation of vascular endothelial growth factor receptor signaling pathway 0.6869878728285754 0.5149702404119071 0.6065738158902902 1.0 0.9312091667295992 2 P18031 1 +Erad pathway 0.3689718821597529 0.5138431549443316 0.6073616533747916 1.0 0.931856652952294 35 Q9UBV2,Q8TCJ2,P51572,P27824,Q8TCT9,P33908,O76024,Q9BUN8,Q4ZIN3,Q96A33 10 +Receptor signaling pathway via stat 0.393398019694566 0.5137067576000903 0.607457026665609 1.0 0.931856652952294 14 Q9H490,Q9NX40 2 +Steroid biosynthetic process 0.3687555053531464 0.5117878138959803 0.6087995199234311 1.0 0.9321526986201868 39 Q15392,Q14739,P00387,P05023,Q15800,Q16850,P08069,P04114,Q14849,P16435,Q53GQ0,Q9H2C2,Q13510,Q14534 14 +Multi organism reproductive process 0.3441653508080117 0.5116196562840714 0.6089172259241291 1.0 0.9321526986201868 153 O94901,Q96QD8,P45880,Q9Y2W6,Q9UIQ6,P05556,O95470,P04114,P04920,Q08431,A0AVF1,P07858,P36896,P05067,P17612,O95067,Q15067,Q07021,P42345,Q9BTX1,P19021,Q9H0H5,Q9BXW9,Q04656,P07686,Q92692,P35613,P09622,P11717,P15529,Q15363,P11166,P41208,Q9BQE5 34 +Canonical wnt signaling pathway 0.3683178553233895 0.5071544901756474 0.6120464242723151 1.0 0.935348055425846 37 Q9P0T7,P20339,P50402,P19022,O75787,Q96K76,P00533,Q9BZK7,Q13641 9 +Developmental maturation 0.3680135850271413 0.5048293986935598 0.6136786653115691 1.0 0.9365835501220297 38 P04062,O75787,Q9Y2W6,O75503,P09622,P51790,Q12834,P07196,P05067,Q9NZJ7 10 +Positive regulation of smooth muscle cell migration 0.5317155468744112 0.5026471157765682 0.6152123972208197 1.0 0.937990492489746 4 Q04656 1 +Regulation of production of molecular mediator of immune response 0.362992816937661 0.5015532357944924 0.6159818215325918 1.0 0.93892233824089 26 P04439,P02786 2 +Positive regulation of intracellular transport 0.3391211908879979 0.5002500789449947 0.6168990002113683 1.0 0.9399954690403732 65 Q92544,Q05D32,Q9P2W9,P55786,Q9NV96,Q9H4M9,Q15154,Q92673,Q9Y6B6,Q9Y282,Q9NR31,P50402,P31751 13 +Cellular response to leucine 0.6823992133726803 0.4998211685856528 0.6172010037617695 1.0 0.9399954690403732 2 P42345 1 +Response to leucine 0.6823992133726803 0.4998211685856528 0.6172010037617695 1.0 0.9399954690403732 2 P42345 1 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.4660982684024977 0.4995551911743747 0.6173883158022324 1.0 0.9399954690403732 6 O76024,O60313 2 +Leukocyte differentiation 0.3524060981228026 0.4929347873156834 0.6220586661981033 1.0 0.940347458916144 57 P04062,Q14739,P24390,P02786,P01889,P05141,Q04656,Q5HYI8,Q15904,P15529,O96005,P05067 12 +Lens development in camera type eye 0.4968420029678076 0.4927847692909258 0.6221646735784965 1.0 0.940347458916144 5 P35222,Q99797,P08670 3 +Negative regulation of organ growth 0.5290259101344539 0.4926839698760558 0.6222359059676135 1.0 0.940347458916144 4 P49840,P11413,Q13043 3 +Regulation of phosphatidylcholine metabolic process 0.4963675269626729 0.4908458908816023 0.6235354496232892 1.0 0.940347458916144 5 P01130,Q8WTV0 2 +Folic acid containing compound metabolic process 0.3947398927676772 0.4896556270339895 0.6243776062221928 1.0 0.940347458916144 13 Q9NRN7,Q9H2D1,Q92820 3 +Negative regulation of chemotaxis 0.4960495163651685 0.4895473154385708 0.6244542651491571 1.0 0.940347458916144 5 O94813 1 +Immune response to tumor cell 0.5278814981950359 0.4884607965263247 0.6252234877016263 1.0 0.940347458916144 4 P04439 1 +Neutrophil migration 0.3941370577194883 0.4861110805528027 0.6268884111368136 1.0 0.940347458916144 13 P35613,Q07021,O94813 3 +Positive regulation of response to endoplasmic reticulum stress 0.4210593373400095 0.4849229688841582 0.6277309886859455 1.0 0.940347458916144 9 P51572,Q4ZIN3,P57088 3 +Response to steroid hormone 0.3311336744635224 0.4833889742782263 0.6288195753936341 1.0 0.9408947236798064 68 P04062,O15118,Q9P1Z2,P16278,P05023,Q96HY6,O95831,O94813,Q969T9,O15173,P16435,P0DP25,Q9H7B4,P19021,P20020 15 +Plasma membrane tubulation 0.4944225721784796 0.4829155694184228 0.6291556864210348 1.0 0.941042343458422 5 Q9UNF0,P50570,Q9Y371,Q9UKS6 4 +Cellular response to vitamin 0.4943179289199156 0.4824897020978512 0.6294581121030431 1.0 0.941059516338014 5 P20020 1 +Multicellular organism reproduction 0.3202981761822315 0.4796411785419989 0.6314825604011163 1.0 0.9425582278089104 123 O94901,Q9Y2W6,P05556,O95470,P04114,P04920,A0AVF1,P07858,P05067,P17612,O95067,Q15067,P42345,Q9BTX1,P19021,Q9H0H5,Q9BXW9,P07686,O94813,Q92692,P35613,P09622,P11717,Q15363,P41208,Q9BQE5 26 +Pointed end actin filament capping 0.6758439855784932 0.4784965085097144 0.6322968587492648 1.0 0.9425582278089104 2 P28289 1 +Response to estrogen 0.3974628963042309 0.4784151906161344 0.6323547238662346 1.0 0.9425582278089104 12 P04062,P09601 2 +Lysosomal membrane organization 0.6755162241887848 0.4774402954330574 0.6330486261254382 1.0 0.9431211515721832 2 Q9Y3E7 1 +Negative regulation of epithelial cell apoptotic process 0.4609997937230105 0.4765737677088073 0.6336656667559264 1.0 0.9432082830750316 6 O76024,P09601 2 +Regulation of fatty acid oxidation 0.5243890750943396 0.4756334102944016 0.6343355686910725 1.0 0.9435541029805814 4 Q06481 1 +Torc2 signaling 0.6096412817444485 0.4752657814765396 0.6345975455737758 1.0 0.943726786739484 3 Q96A49 1 +Positive regulation of nervous system development 0.3640983671461764 0.4742297480734381 0.635336082097445 1.0 0.9446079326794694 40 O15031,P98164,Q9UQB8,P42345,O94813,P55209,P07196,O14786,Q13641 9 +Release of sequestered calcium ion into cytosol by endoplasmic reticulum 0.5232739375272909 0.4715571519091159 0.6372429168217373 1.0 0.945967654674753 4 P0DP25 1 +Regulation of binding 0.2986713480811851 0.4706302466319476 0.6379048041622588 1.0 0.9461738553463832 96 O75844,P09601,P62942,Q96D46,Q9BUN8,O14786,P05067,P48681,P40855,P17612,Q92673,P0DP25,P16615,P60228,Q9NVN8,Q96HY6,Q15691,P10586,O75503,O75955,Q07954 21 +Sensory organ development 0.3435050130521911 0.4670283496119641 0.6404795953196041 1.0 0.9490860424322244 61 O75569,P39210,Q9Y6M7,Q9NP72,O14786,P48681,P54802,Q9P273,P20020,Q8NF37,Q15042,Q5SZK8,Q16706,P00533,P42892,Q15293,O75386,Q15555,Q13308,Q8NBN7 20 +Presynaptic modulation of chemical synaptic transmission 0.6722386102917017 0.4669317360100793 0.6405487186982675 1.0 0.9490860424322244 2 Q00535 1 +Striated muscle contraction 0.3586820110867306 0.4655690076417622 0.6415240312684776 1.0 0.9503134779656014 18 P17612,P16615,P05023,P42345,Q14126,P0DP25,P10253,Q96PU5 8 +Sequestering of calcium ion 0.3730744607657824 0.4642140276793231 0.64249441197081 1.0 0.9512829963037966 16 P62942,O95202,P0DP25 3 +Positive regulation of excitatory postsynaptic potential 0.6712553261225997 0.4637983353282887 0.642792236123102 1.0 0.9513207447907452 2 Q9UQB8 1 +Response to salt stress 0.44626817539482 0.4635234639628108 0.6429892001596123 1.0 0.9513355863898568 7 O95202 1 +Cellular response to biotic stimulus 0.3622829843032079 0.4619889819714641 0.6440892217073577 1.0 0.9517732144072288 34 Q86UE4,O75844,Q8WTV0,Q9NUQ9,Q96A33 5 +Coenzyme a biosynthetic process 0.4891926247679481 0.4617342384498135 0.6442719148288152 1.0 0.9517732144072288 5 Q8WVC6 1 +Response to inorganic substance 0.3043915676383946 0.4615703495801811 0.6443894615404169 1.0 0.9517732144072288 104 P35613,O15118,P02786,P09601,Q96QD8,Q99538,Q99720,Q04656,Q92542,O60888,Q6NUK1,O95831,P04114,P05067,P0DP25,P19021,Q96PU5 17 +Regulation of bmp signaling pathway 0.3895825418222032 0.4594337760549482 0.6459226979657113 1.0 0.952883871078782 13 Q92673 1 +Ovulation cycle 0.4013625796925441 0.4592176923174603 0.6460778467549249 1.0 0.952883871078782 10 O95470,O94813,P19021 3 +Cytokine mediated signaling pathway 0.3592191784383857 0.4576725885884362 0.6471876842924358 1.0 0.9534323416599648 47 Q06481,Q8TCT8,P15260,Q16739 4 +Glycerolipid metabolic process 0.3440540578581471 0.4555432062697996 0.6487184913091273 1.0 0.9534440668228308 60 Q96N66,Q9NTJ5,P04114,Q9BTU6,Q9BVG9,Q8NCC3,Q9UG56,Q9NRX5,Q9NPH0,Q92673,Q9H490,P01130,Q53H12,Q8NF37,O14735,Q92643,P35790,Q9BZK7,Q8WTV0,Q9NX62,O43292,P48651,Q9UBF8 23 +Negative regulation of erbb signaling pathway 0.4153343366555805 0.4555332572521218 0.6487256471213696 1.0 0.9534440668228308 9 Q99538,P00533 2 +Negative regulation of response to biotic stimulus 0.3647293922554681 0.4552024144578285 0.648963623645719 1.0 0.9534440668228308 17 P04439,O43657,P01889,Q96J02 4 +Positive regulation of potassium ion transport 0.4561314984536683 0.4548144195445583 0.6492427555769977 1.0 0.9534440668228308 6 Q4KMQ2 1 +Centriole centriole cohesion 0.6030387362223624 0.4537573460944429 0.650003486910437 1.0 0.9540222570419488 3 Q9C0F1 1 +Transforming growth factor beta receptor signaling pathway 0.3556071190262749 0.4527837112248367 0.6507044939197844 1.0 0.9540222570419488 25 Q06481,Q92896 2 +Actin mediated cell contraction 0.3774948058313641 0.4520373458212397 0.6512420785951576 1.0 0.9544370200344529 15 Q14126,P16615,Q9UM22,Q96PU5 4 +Sprouting angiogenesis 0.3831054887399044 0.4514301398093067 0.6516795647569185 1.0 0.9544779989784584 14 P57105,O94813,O14786,P09601 4 +Ameboidal type cell migration 0.302371688434913 0.4510801512217455 0.6519317827050086 1.0 0.9544779989784584 78 P19022,P09601,Q8WTV0,Q99538,Q5SNT2,P05556,Q06481,P42785,Q9NQC3,Q15555,O95470,Q07021,P57105,O94813,Q13685,O14786,P36896,Q13641 18 +Multicellular organism aging 0.4143509865553642 0.4505122515970118 0.6523411221354456 1.0 0.9544779989784584 9 O75844 1 +Very long chain fatty acid catabolic process 0.516784492962553 0.4480298717146385 0.6541316382832509 1.0 0.9546294461164636 4 Q15067,O14678 2 +Positive regulation of dna binding transcription factor activity 0.3603037512937949 0.4440854918125371 0.6569807753262942 1.0 0.9572091521589632 41 Q86UE4,P02786,O75955,P60900,P05067,Q96HY6 6 +Regulation of response to biotic stimulus 0.3392616802731427 0.4411228557619089 0.6591240578761806 1.0 0.9593828405302977 62 P11279,O75844,P01889,Q96J02,P04439,Q06481,Q07021,Q9NZ08,O43657,Q9NUD5,Q8IZ81 11 +Positive regulation of neurotrophin trk receptor signaling pathway 0.6627335299901636 0.437022087440084 0.6620953297925762 1.0 0.9607659686918294 2 Q7L576 1 +Regulation of neurotrophin trk receptor signaling pathway 0.6627335299901636 0.437022087440084 0.6620953297925762 1.0 0.9607659686918294 2 Q7L576 1 +Cellular response to chemical stress 0.2888372701697513 0.4359051972532003 0.6629055141578479 1.0 0.961336155606024 82 O75569,P09601,P39210,O75915,P07237,P04062,Q99720,P14672,O95831,Q9BPX6,Q969S3,Q9BXW9,Q9NR28,P16615,Q04656,Q6NUK1,P00533,P00374,P11166,O95202 20 +Regulation of striated muscle contraction 0.3967499739368996 0.4345282521558797 0.6639048834891164 1.0 0.9616538141989924 10 P17612,P16615,P05023,Q14126,P0DP25 5 +Regulation of ras protein signal transduction 0.3569220989256804 0.4337621836015015 0.6644611454048093 1.0 0.9616538141989924 30 Q9Y624,Q13501,O75955,Q15555,Q5HYI8,Q96AG4,O14786 7 +Post embryonic development 0.374532300537177 0.4337210183088699 0.6644910418100938 1.0 0.9616538141989924 15 P04114,Q96A33,Q9NX62,P11717 4 +Glycerol ether metabolic process 0.4509353462421969 0.4318018136138057 0.6658854612826559 1.0 0.962355266169351 6 Q6IAN0,O00116,P43034,Q8WVX9,O15228 5 +Receptor catabolic process 0.4106363096645693 0.4316207351705918 0.6660170855835807 1.0 0.962355266169351 9 Q99538 1 +Inner ear receptor cell development 0.4504265696322095 0.4295608535253928 0.6675151184343602 1.0 0.9640093320108014 6 P54802 1 +Positive regulation of intracellular signal transduction 0.3318484187461583 0.4290455670626637 0.6678900640533683 1.0 0.9640093320108014 144 O75569,Q6IAA8,P09601,P62942,P05556,O75915,Q8IUH4,Q9NUD5,O14786,P05067,Q86UE4,P19022,P02786,Q53EL6,Q07021,O00560,P08069,O43657,Q9NQC3,Q13641,Q969S3,P06756,Q8TB61,P98164,Q07820,P00533,P04899,Q9Y251,Q9Y624,P61927,Q9HB90,Q15555,O60826,Q96AG4,Q8WVQ1 35 +Negative regulation of protein modification by small protein conjugation or removal 0.3582275073513903 0.4260589194071224 0.6700649135305365 1.0 0.9656159335328672 36 Q13501,Q96FW1 2 +Postsynapse organization 0.3569400129543378 0.4257685121054327 0.6702765334481238 1.0 0.9657057672329428 32 O15258,Q15375,P19022,Q9UQB8,Q99538,P08069,P07196,O14786 8 +Negative regulation of calcium ion transport 0.4094380165576387 0.4255529677658332 0.6704336176145502 1.0 0.9657170056442942 9 P0DP25,P21796 2 +Positive regulation of cell junction assembly 0.3917972136733363 0.4250423393200158 0.6708058103422128 1.0 0.9657580228992934 11 O75955,Q13641 2 +Positive regulation of receptor clustering 0.6588003933136612 0.4248994664091388 0.6709099636589 1.0 0.9657580228992934 2 Q15334 1 +Protein trimerization 0.5099932847400606 0.423778683518462 0.6717272254790305 1.0 0.9660960483219484 4 Q99720,Q15758 2 +Positive regulation of ossification 0.4795483515728579 0.4232559482731757 0.6721085307507093 1.0 0.9660960483219484 5 Q4KMQ2 1 +Cardiac muscle cell action potential 0.3783241703914964 0.4228426983481007 0.6724100325041671 1.0 0.9660960483219484 14 Q14126,P16615,Q96PU5,P0DP25 4 +Negative regulation of calcium ion transmembrane transport 0.4230422388047021 0.4220420577975469 0.6729943192932564 1.0 0.9660960483219484 8 P0DP25,P21796 2 +Regulation of dendrite development 0.3456665331438831 0.421583093278925 0.6733293488045282 1.0 0.9660960483219484 20 P98155,Q96PU5,Q12834 3 +Regulation of cellular component size 0.290973578883307 0.4214309585853111 0.6734404166050951 1.0 0.9660960483219484 81 P20339,Q15375,P54105,P55011,Q9NUQ9,P07196,Q04656,P42345,P51790,O15511,O94813,Q4KMQ2,Q96J84,O14786,Q9NQC3 15 +Skeletal system development 0.3551112497909799 0.4213024139728868 0.6735342677279312 1.0 0.9660960483219484 47 O75844,O75386,Q04656,Q92896,Q7RTS9,Q9NX62,P07686,O95470,Q15904,P16435,Q15043,Q96HY6 12 +Negative regulation of viral entry into host cell 0.5921311475409854 0.4190116286645071 0.6752076337738893 1.0 0.9663115167099326 3 Q12899,Q14258 2 +Negative regulation of viral life cycle 0.5921311475409854 0.4190116286645071 0.6752076337738893 1.0 0.9663115167099326 3 Q12899,Q14258 2 +Peptidyl tyrosine modification 0.3572038855409725 0.4161803223036995 0.6772780577153745 1.0 0.9663237219587026 38 Q15375,Q9H223,P42345,P00533,O14786,P05067 6 +Positive regulation of epithelial cell proliferation 0.3494695627287944 0.4148078698793359 0.6782825579519516 1.0 0.9673706577611896 24 P09601,Q04656,P00533,P07942,Q9NQC3 5 +Carbohydrate derivative biosynthetic process 0.3348414629635773 0.4128587427563037 0.6797101100481693 1.0 0.9678724855605562 150 Q9HC07,Q8NBZ7,O75964,Q9BT22,Q9UMR5,Q9Y287,Q2TAA5,Q7LGA3,Q99805,Q9H9S5,O15118,P14672,Q9BXS4,Q10472,P50897,Q9H490,Q9NQX7,P33908,P46977,Q8TB61,P06865,Q04656,Q92542,Q10471,P00403,Q8WVC6,Q92643,Q8WVQ1,O43505,Q8NBX0,Q9BV10,P09622,Q16739,Q9NZ01 34 +Hydrogen peroxide biosynthetic process 0.5895828863296935 0.4110418873857447 0.6810418205272264 1.0 0.968115337701379 3 P00403 1 +Atp metabolic process 0.2999132458445515 0.4103804862809082 0.6815268585395085 1.0 0.968115337701379 103 P52789,O75964,P14406,Q7KZN9,Q9Y6M9,P05067,Q9BRR6,Q9UDW1,P03886,O75438,P03915,O14949,Q04656,O96000,P00403,O43676,O95169,Q9BSK2,Q9H3K2,P09622,P13073 21 +Protein demethylation 0.4456339056886871 0.4085633896126732 0.682860102297878 1.0 0.9682337939818167 6 Q8IUF8,Q9Y2K7 2 +Regulation of cellular component movement 0.3371649438947556 0.4071196055441187 0.6839201445031766 1.0 0.9682337939818167 154 P09601,Q08722,Q14126,O00592,P36896,P05067,O00560,Q13685,Q92673,P07942,Q9NQC3,P06756,Q9NUQ9,Q99538,Q06481,P16615,Q96G23,Q04656,P00533,O94813,Q96HY6,O15031,Q15555,P43121,Q07954,Q4KMQ2,P11279,P31751 28 +Glycerol 3 phosphate metabolic process 0.6529006882989126 0.4070040488691167 0.6840050144530689 1.0 0.9682337939818167 2 P43304 1 +Response to interleukin 1 0.3699468600596584 0.4055596581923611 0.6850661755235428 1.0 0.9684776427996724 15 P05067 1 +Cobalamin metabolic process 0.5045709478657401 0.4047022791669602 0.6856963666581888 1.0 0.9684776427996724 4 Q9NPF0 1 +Labyrinthine layer development 0.4193760262725748 0.4044732013306715 0.6858647805965934 1.0 0.9684776427996724 8 Q02750,Q15363,P31749,P28482,Q15738,P62993,Q9NR09 7 +Catechol containing compound metabolic process 0.4443396446812643 0.4029287690907348 0.6870006265219424 1.0 0.9684776427996724 6 Q04656 1 +Dopamine metabolic process 0.4443396446812643 0.4029287690907348 0.6870006265219424 1.0 0.9684776427996724 6 Q04656 1 +Mitochondrial outer membrane permeabilization 0.4047249319052508 0.4018182031881377 0.6878178244926076 1.0 0.9689663559761932 9 P45880 1 +Cell chemotaxis 0.3551601503115577 0.4002539767451595 0.6889694621798799 1.0 0.9699550491494326 37 P35613,P55011,Q96JJ3,Q99538,O94813,Q4KMQ2,O14786,Q13641 8 +Cardiac ventricle morphogenesis 0.4318287204436992 0.3971708586458026 0.6912414700687 1.0 0.9705346836340464 7 P16870 1 +Leukocyte chemotaxis 0.3497941836313154 0.3962523811694308 0.6919188524598052 1.0 0.9705346836340464 27 P35613,P55011,Q99538,O94813,Q4KMQ2 5 +Regulation of cyclin dependent protein kinase activity 0.3557312252964478 0.3959132012627575 0.6921690619478928 1.0 0.9705346836340464 17 P25054,Q9P287,O75832,O95067,P53350,P42574,P49736,Q16543,P00533,P08238,P14635,P20248,P31749,O00410,O95373,Q9BZE4 16 +Neural plate development 0.648639790232704 0.3943002441677409 0.6933593830375924 1.0 0.9705346836340464 2 P35222 1 +Foregut morphogenesis 0.648639790232704 0.3943002441677409 0.6933593830375924 1.0 0.9705346836340464 2 P35222 1 +Neuron projection organization 0.3429650869375787 0.3929940683515937 0.6943238624319994 1.0 0.9705346836340464 21 P05067 1 +Dorsal ventral neural tube patterning 0.5011791766561754 0.3929046644034061 0.6943898963744366 1.0 0.9705346836340464 4 O75386 1 +Cellular response to growth hormone stimulus 0.4708005249343824 0.3890608662434704 0.6972311215141216 1.0 0.9729503156926502 5 P40763,Q05397,P18031,P07948 4 +Cellular carbohydrate catabolic process 0.3474870532511406 0.388999479750457 0.6972765312367499 1.0 0.9729503156926502 18 P10253,Q14108 2 +Positive regulation of establishment of protein localization 0.2884991160960909 0.3878644699696719 0.6981163326486988 1.0 0.9729503156926502 81 P49755,Q92544,P17612,Q9H4A5,Q05D32,P55786,Q9NV96,O00429,Q15154,Q92673,Q9Y6B6,Q9Y282,Q9NR31,P50402,P31751 15 +Regulation of cytoplasmic mrna processing body assembly 0.6463454605047458 0.3875380119289303 0.6983579496771668 1.0 0.9729503156926502 2 Q9HBH5 1 +Negative regulation of lipase activity 0.5816069473817373 0.3864751653961072 0.6991447917462454 1.0 0.9729503156926502 3 Q99523 1 +Copper ion homeostasis 0.4404010635613555 0.3858792561165471 0.6995860942790555 1.0 0.9729503156926502 6 P05067 1 +Lymphocyte activation involved in immune response 0.3491265344678134 0.3851796818241175 0.7001042957675949 1.0 0.9729503156926502 28 P15529,P11279,Q04656,P02786 4 +Dopamine receptor signaling pathway 0.4401651909458446 0.3848629453137113 0.7003389605806694 1.0 0.9729503156926502 6 Q92542,P08754 2 +Pigment metabolic process 0.345020198348188 0.3823647842342257 0.7021908075816872 1.0 0.9729503156926502 24 P30519,P09601,Q04656,Q7KZN9,O00264 5 +Coronary vasculature development 0.414398211344556 0.3808267371731886 0.7033318181923947 1.0 0.9730225688380242 8 O14786,Q13308,P98164 3 +Formation of translation preinitiation complex 0.4001132224308631 0.3788065402386207 0.7048315302998724 1.0 0.9736995548202608 9 P55010 1 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.385759262923754 0.3765129193106331 0.7065356126993458 1.0 0.9747485489284538 10 Q92896 1 +Positive regulation of protein tyrosine kinase activity 0.4675196850393836 0.3764221372209316 0.706603091046486 1.0 0.9747485489284538 5 P18031,Q15334,Q92796,Q13177 4 +Ectoderm development 0.5767213114754136 0.3717189995383307 0.7101020774852391 1.0 0.9775770448403628 3 P35222,Q9HCM4 2 +Small rna loading onto risc 0.4661374204755349 0.3711289506814483 0.7105414888799089 1.0 0.9775770448403628 5 Q5KU26 1 +Positive regulation of peptidyl tyrosine phosphorylation 0.3583164853563042 0.3705816889316192 0.7109491225930762 1.0 0.9777061807088882 16 Q9H223,Q92796,P42345,P18031,O14786 5 +Striated muscle cell differentiation 0.3512686834159865 0.3687603151206388 0.7123063870707818 1.0 0.9778895668912844 41 P10644,O75844,P19022,P05556,O75955,Q9P2K5,Q8IV08,Q99523,Q9H4M9,Q16527,Q9H7B4 11 +Post translational protein modification 0.3776942911255021 0.3676017049615904 0.7131702433383071 1.0 0.9778895668912844 12 Q9Y4P8,O60725,Q32P28,Q9HA64,P46977 5 +Rab protein signal transduction 0.4651851808715046 0.3674936044605187 0.7132508615332374 1.0 0.9778895668912844 5 Q14964,P51151 2 +Cellular response to ionizing radiation 0.3366117626048848 0.3673607349447271 0.7133499561230439 1.0 0.9778895668912844 19 Q86UE8 1 +Regulation of gliogenesis 0.3734335719091221 0.3665101090826458 0.7139844706653291 1.0 0.9781375562757336 13 P01130,Q96G23 2 +Vesicle mediated transport between endosomal compartments 0.3433169156546868 0.3609100378679749 0.7181666995035134 1.0 0.9799963131429724 18 P51149,Q92673,Q9UNK0 3 +Response to oxidative stress 0.2883326987985045 0.3602496948907883 0.7186604148226259 1.0 0.9799963131429724 93 Q15392,O75569,P09601,P39210,O43169,Q9P2K5,O75915,P07237,P05067,P04062,P30519,Q99720,O95831,P52272,P03915,Q969S3,Q9BXW9,Q9NR28,P16615,Q04656,Q6NUK1,P00533,P00374,Q15165 24 +Hippocampus development 0.3624783937976712 0.360232912220581 0.7186729641688143 1.0 0.9799963131429724 15 P08069,O14949,Q13144,P07196 4 +Muscle cell development 0.3457442883692964 0.3599791730651816 0.7188627084460162 1.0 0.9799963131429724 28 P10644,O75844,P16615,P05556,Q16527,Q9H7B4 6 +Histone h3 k4 demethylation 0.5726746303400019 0.3596704106695486 0.71909362207461 1.0 0.9799963131429724 3 Q8IUF8 1 +Regulation of cell migration involved in sprouting angiogenesis 0.4627237939408839 0.358139469403787 0.7202389430629825 1.0 0.9808671253435456 5 P09601 1 +Neuron projection extension 0.3493030340652124 0.3571486165656751 0.7209805504728024 1.0 0.9808671253435456 35 Q9NQC3,O94813,Q92581,O14786,Q96PU5 5 +Uv protection 0.462143617939875 0.355943663679521 0.7218827554719878 1.0 0.9816816365668044 5 Q92889,Q9BRK5 2 +Bone resorption 0.4223027347705179 0.3544686631522632 0.7229876846118943 1.0 0.9817345789126092 7 P02786 1 +Mesonephric tubule morphogenesis 0.5708196721311515 0.3542011366052225 0.7231881518508763 1.0 0.9817345789126092 3 P35222,Q13418 2 +Embryonic placenta development 0.3711589093448095 0.3536601907163891 0.7235935600394454 1.0 0.9817345789126092 13 P00533 1 +Positive regulation of lamellipodium assembly 0.3751230124996685 0.353499210745711 0.7237142203558806 1.0 0.9817345789126092 12 Q16625 1 +Mammalian oogenesis stage 0.6332350049164137 0.3499813421101437 0.7263527000806056 1.0 0.9829155929666464 2 Q96MU7 1 +Regulation of phosphoprotein phosphatase activity 0.3485430722750544 0.3493112015041922 0.7268556898965348 1.0 0.9829155929666464 17 Q15257,P62942,P42345,P04899,P0DP25 5 +Electron transport chain 0.3190960265357554 0.34883251378566 0.7272150523497913 1.0 0.9829155929666464 68 P04062,O14949,Q9H3K2,P09622,O96000,Q9Y6M9,Q7KZN9,Q9P0J0,P00403,P16435,Q9UDW1,O43676,Q15526,P03886,O75438,P13073,P03915 17 +Negative regulation of protein polymerization 0.3399722374161964 0.3459123349769421 0.7294085982886394 1.0 0.9829517894936116 24 Q9NUQ9,P45880 2 +Cellular component disassembly involved in execution phase of apoptosis 0.3934302419860179 0.3458623178016498 0.7294461889660435 1.0 0.9829517894936116 9 O00115 1 +Ubiquitin dependent erad pathway 0.3452224436229399 0.3449226603764034 0.730152514337072 1.0 0.9829517894936116 30 Q9UBV2,Q8TCJ2,P51572,P27824,O76024,Q9BUN8,P33908,Q96A33 8 +Negative regulation of striated muscle cell differentiation 0.4589895013123438 0.344067855888357 0.7307952560178683 1.0 0.9829517894936116 5 P49840,P11413,Q13547,O94826 4 +Positive regulation of torc1 signaling 0.4867169563791298 0.3438407400735776 0.730966059975213 1.0 0.9829517894936116 4 Q9P2J5,Q9NWS0,Q96EE3 3 +Cerebral cortex development 0.3450710344805625 0.3437861255857953 0.7310071351533383 1.0 0.9829517894936116 30 Q96QD8,P19022,Q96N66,P00533,O94813,P11166,P07196,P07942,Q9NQC3 9 +Integrin mediated signaling pathway 0.3476515379445123 0.3435837828840785 0.7311593224192345 1.0 0.9829517894936116 17 O14786,P06756,Q08722 3 +Action potential 0.3344665975368562 0.3424590045476132 0.7320054905056204 1.0 0.9829517894936116 20 P04062,P05023,P16615,P42345,Q14126,P0DP25,Q96PU5 7 +Histone lysine demethylation 0.4584019327118677 0.3418672116470777 0.7324508258502056 1.0 0.9829517894936116 5 Q8IUF8,Q9Y2K7 2 +Female meiosis chromosome segregation 0.5665573770491845 0.3417641753128008 0.7325283718533182 1.0 0.9829517894936116 3 P53350,P33981 2 +Negative regulation of proteasomal ubiquitin dependent protein catabolic process 0.3327171290107589 0.3402652822684748 0.7336567596746559 1.0 0.9829517894936116 19 O00560,Q86UE8 2 +Regulation of cell junction assembly 0.3470765617029037 0.3397301188376416 0.7340597778242115 1.0 0.9829517894936116 35 Q9Y624,Q15375,O75955,P05067,Q13641 5 +Extracellular matrix disassembly 0.3921018891862102 0.339374278854651 0.7343277925533944 1.0 0.9829517894936116 9 Q07954 1 +Rho protein signal transduction 0.3389491078225165 0.3385737585353393 0.7349308538512846 1.0 0.9829517894936116 24 Q9Y624,Q9P035,O75955,P05556,P57105,O14786 6 +Detection of abiotic stimulus 0.4052891435505144 0.3382252857356358 0.7351934222729701 1.0 0.9829517894936116 8 Q15555 1 +Bone remodeling 0.4043484640174115 0.3338785008730079 0.7384712435971907 1.0 0.9829517894936116 8 Q92791,O14773,P02786 3 +Response to osmotic stress 0.3330907915217651 0.3328769710644006 0.7392271534837564 1.0 0.9829517894936116 20 O95202,P11166,P55011,P14672 4 +Positive regulation of fatty acid transport 0.6266797771222639 0.3319184302350738 0.7399508532770795 1.0 0.9833160459181042 2 P14174 1 +Copii coated vesicle cargo loading 0.4039013818522078 0.3318161836503032 0.7400280632078629 1.0 0.9833160459181042 8 Q9NR31 1 +Vesicle budding from membrane 0.3459411904767364 0.3308778214013156 0.7407367752262699 1.0 0.9836849212320936 35 P49755,Q9H4A5,P14672,Q15363,P62820,Q9HCU5,Q9Y6B6,P51149,Q9NR31,Q96CW1 10 +Immune response regulating cell surface receptor signaling pathway 0.3444879694860924 0.3300209624738583 0.7413841228998681 1.0 0.984030027556 32 P04439,Q06481,Q08722 3 +Regulation of collagen metabolic process 0.5622808299346312 0.3294714642061728 0.7417993592908341 1.0 0.9841968042902453 3 P05556 1 +Vitamin metabolic process 0.3416106494756076 0.3294216444916985 0.7418370100045193 1.0 0.9841968042902453 28 P04062,Q9NRN7,P98164,Q99538,P38435,P11166,Q9H2D1 7 +Regulation of protein maturation 0.3763676071836293 0.3279741818202976 0.7429311837982984 1.0 0.9845978863441344 10 Q9BXS4 1 +Protein k48 linked ubiquitination 0.3896846197483877 0.3276213063166837 0.7431980102026454 1.0 0.9845978863441344 9 Q96J02 1 +Regulation of receptor internalization 0.3734419572378188 0.3266530800672952 0.7439302917221868 1.0 0.9845978863441344 11 O00560 1 +Negative regulation by host of viral transcription 0.4814693342079313 0.3265642052760016 0.7439975204453435 1.0 0.9845978863441344 4 Q13148,Q9H1E3,Q13547 3 +Smooth muscle cell proliferation 0.3306674726476191 0.3261090903990768 0.744341819525816 1.0 0.9845978863441344 19 Q14344,Q53EL6,P09601,P08754,P08069,P04899 6 +Negative regulation of protein containing complex assembly 0.3453165969300826 0.3260169231390287 0.7444115512296212 1.0 0.9845978863441344 35 Q9NUQ9,O94813,Q92673,P45880 4 +Regulation of low density lipoprotein particle clearance 0.4261425431117609 0.325474998922583 0.7448216014293068 1.0 0.9845978863441344 6 P01130 1 +Cellular response to hormone stimulus 0.3119667078881488 0.3248222834945002 0.745315578477385 1.0 0.9845978863441344 127 P05023,P04114,O15173,Q15043,O14654,P07858,Q92572,P56192,O15118,P17612,P42785,P14672,P08069,O95831,Q969T9,Q92673,P20020,Q9UQB8,Q9P1Z2,Q06481,P04899,O94813,Q9H7B4,Q96HY6,Q9BSK2,P16435,Q16739,P31751,P43490 29 +Polysaccharide biosynthetic process 0.3614107024009664 0.3238463571406204 0.7460543578757377 1.0 0.9845978863441344 14 Q7LGA3,O43505 2 +Cellular response to virus 0.3343990943381721 0.3232751633980784 0.7464868617604923 1.0 0.9845978863441344 22 O43657 1 +Regulation of cellular response to transforming growth factor beta stimulus 0.3562154516150478 0.322798811149204 0.7468476134173689 1.0 0.9845978863441344 15 Q92896 1 +Positive regulation of cell migration involved in sprouting angiogenesis 0.4801820018804349 0.322370975744086 0.7471716695299959 1.0 0.9845978863441344 4 P09601 1 +Response to ether 0.5596721311475382 0.3220660834730705 0.7474026318910074 1.0 0.9845978863441344 3 Q14103,Q6PKG0 2 +Glycosyl compound metabolic process 0.3386934480513522 0.3215379562359466 0.7478027531309435 1.0 0.9845978863441344 26 P04066,P06280,O60725,P08236,Q9BTY2 5 +Myeloid leukocyte differentiation 0.3376252016246737 0.3212564472369517 0.7480160585388824 1.0 0.9845978863441344 25 Q15904,P04062,P02786,P05067 4 +Regulation of action potential 0.3749740308289141 0.3208623089094627 0.7483147380149795 1.0 0.9845978863441344 10 P04062,P16615,Q14126 3 +T cell activation involved in immune response 0.3881602312341153 0.3202460241741272 0.7487818365521315 1.0 0.9846317673485148 9 Q04656 1 +C terminal protein amino acid modification 0.5589895636007752 0.3201402660866518 0.7488620026827475 1.0 0.9846317673485148 3 O60725 1 +Regulation of mitochondrial membrane permeability involved in apoptotic process 0.3747257346195655 0.3195977594070066 0.7492732730975638 1.0 0.984972323444044 10 P45880 1 +Cd40 signaling pathway 0.4791309872353699 0.3189608822082381 0.7497561761173182 1.0 0.9850918238365792 4 Q9BXW9 1 +Face development 0.4009382155173427 0.3182073248463077 0.7503276769001785 1.0 0.98513730267335 8 Q15042 1 +Cellular response to unfolded protein 0.3408564488873698 0.3178655343060608 0.7505869373493614 1.0 0.98513730267335 29 P48723,O76024,Q15363,Q9BUN8,Q9Y4P3,Q96HY6 6 +Positive regulation of calcium ion transport 0.3647013757778259 0.3175485862088148 0.750827379082156 1.0 0.98513730267335 13 O76024,P0DP25 2 +Myoblast fusion 0.4241399589112837 0.3171693760307387 0.7511150855902624 1.0 0.98513730267335 6 Q9H4M9,O75955 2 +Syncytium formation 0.4241399589112837 0.3171693760307387 0.7511150855902624 1.0 0.98513730267335 6 Q9H4M9,O75955 2 +Cell morphogenesis 0.3391845047048697 0.3169703895429883 0.7512660703514227 1.0 0.98513730267335 167 O75844,P62820,P07237,O14786,P05067,Q96PU5,Q15375,P19022,P98155,P07942,Q9NQC3,Q13641,P06756,P98164,P38571,Q06481,Q04656,P07686,P00533,O94813,Q9HCE1,Q92581,O00264,Q9Y624,O15031,P35613,P42892,O75955 28 +Synaptonemal complex organization 0.4136572554169523 0.3165543935679455 0.7515817459246978 1.0 0.98513730267335 7 P54652,P46379,Q92791,P53350,O60216,Q96KQ7 6 +Regulation of rig i signaling pathway 0.4130791515867961 0.3140497943481137 0.7534832200416648 1.0 0.9851946106102316 7 Q9NUD5 1 +Anatomical structure homeostasis 0.3445196289474251 0.3140278037354889 0.7534999218020659 1.0 0.9851946106102316 38 Q9Y624,P02786,Q16625,P55011,P38571,Q15555,P51790,O14773,P11166,P51149,P10253,P20020 12 +Columnar cuboidal epithelial cell development 0.4507874015748129 0.3136904330789273 0.7537561675833451 1.0 0.9851946106102316 5 P49840,P31749,P19022,Q9NQ88 4 +Ether biosynthetic process 0.450787401574803 0.3136904330788911 0.7537561675833726 1.0 0.9851946106102316 5 O15228,O00116,Q6IAN0,Q8WVX9 4 +Regulation of alpha beta t cell activation 0.3735450556584742 0.3135955184290825 0.7538282637412166 1.0 0.9851946106102316 10 P04439 1 +Medium chain fatty acyl coa metabolic process 0.6191412651589567 0.3117581888233924 0.7552243018873264 1.0 0.9857841018783524 2 O00154 1 +Regulation of anaphase promoting complex dependent catabolic process 0.5548211623287365 0.3084869725128516 0.7577118116457 1.0 0.9886320511367552 3 Q12834 1 +Monovalent inorganic anion homeostasis 0.5541844846282507 0.3067234775355443 0.7590538581156796 1.0 0.989983751643212 3 P55011 1 +Regulation of immune system process 0.3473331991020005 0.3060877362233394 0.7595378451766923 1.0 0.9904153034565658 181 P09601,Q08722,Q9NUD5,Q96J02,P36896,P05067,Q5ZPR3,P02786,O15400,P53634,Q9NZ08,O43657,Q9NQC3,P01130,O00115,P10644,P01889,Q9NUQ9,Q99538,Q06481,P30825,O94813,O96005,P51809,P04439,O75955,P15529,Q4KMQ2,Q5KU26,P11279,Q8TCT8 31 +Defense response 0.3593464681021078 0.3048875562870355 0.76045179348408 1.0 0.9907493851087504 201 O75844,P09601,Q08722,Q8IV08,P62820,P15260,Q9NUD5,Q96J02,P05067,P04062,Q9NVI7,Q08380,P02786,P10321,O00584,P53634,Q07021,P60900,Q9NZ08,O43657,Q9BPX6,Q99735,Q8IZ81,P01130,Q9UNK0,P01889,P38571,Q06481,Q9HCE1,Q9Y624,P51809,P48960,P04439,Q03518,P15529,Q13137,Q4KMQ2,Q5KU26,P11279,Q9BQE5 40 +Regulation of cell projection assembly 0.3413919072949098 0.3013996044605949 0.763109795893032 1.0 0.992502396549442 47 Q16625,Q04656,Q15555,O00592,O94813,Q9Y277 6 +Positive regulation of lipid storage 0.4202434107679402 0.3011433574509338 0.7633051801665851 1.0 0.992502396549442 6 P04114,Q8WTV0 2 +Gland development 0.3167741224663649 0.300966843253944 0.7634397782083822 1.0 0.992502396549442 67 P52789,Q9UNS2,O75844,P09601,Q04656,P00533,P11717,P07602,Q13505,Q9NQC3,P19021,P31751,Q9NZJ7 13 +Keratinocyte migration 0.4732003758316278 0.2999482007439671 0.764216667139278 1.0 0.9928067405936936 4 Q15555 1 +Regulation of keratinocyte migration 0.4732003758316278 0.2999482007439671 0.764216667139278 1.0 0.9928067405936936 4 Q15555 1 +Positive regulation of multicellular organismal process 0.3542315854132133 0.2998994690478002 0.7642538393388141 1.0 0.9928067405936936 193 P52789,P09601,P05023,P04920,P62820,P15260,Q9NUD5,Q96J02,P36896,P05067,Q5ZPR3,O14786,Q86UE4,P04062,P02786,Q07021,O00560,Q9NZ08,Q92673,Q9NQC3,Q13641,P98164,O75787,Q9NUQ9,Q06481,P16615,O94813,P55209,P23786,Q9Y251,P51809,O15031,P04439,O75955,Q07954,P15529,P16435,Q4KMQ2 38 +Neutral lipid metabolic process 0.3572098969015629 0.2998549907749525 0.7642877675307767 1.0 0.9928067405936936 14 Q8WTV0,Q8NCC3,P04114,Q92673,P01130 5 +Necrotic cell death 0.34674075669665 0.2991830534006458 0.7648003788784252 1.0 0.992985936207049 16 P12235,Q13510,P00403 3 +Positive regulation of epithelial cell migration 0.339060123442802 0.2989768049691744 0.7649577435190147 1.0 0.992985936207049 30 Q8WTV0,P09601,Q99538,Q15555,Q13685,Q9NQC3 6 +Rna interference 0.3834421500593181 0.2976044091789676 0.7660051089495112 1.0 0.99315311184155 9 Q5KU26,O75569 2 +Regulation of skeletal muscle cell differentiation 0.550819672131142 0.2974766806080122 0.7661026088085054 1.0 0.99315311184155 3 P17844,Q9BYT8 2 +Placenta blood vessel development 0.4191007548408305 0.2964783116850748 0.7668648276157968 1.0 0.9935606989478448 6 Q02750,Q15363,P31749,P28482,Q15738 5 +Positive regulation of vascular associated smooth muscle cell proliferation 0.5502687309379486 0.2959744564613604 0.7672495886975055 1.0 0.9938601500368768 3 P04899 1 +Mechanoreceptor differentiation 0.4078948779164006 0.2917702183925397 0.7704623172089342 1.0 0.9954311029961056 7 P54802 1 +Negative regulation of cell size 0.469099784576952 0.2870360195704432 0.7740847404954203 1.0 0.9978493338197336 4 P42345 1 +Protein k63 linked ubiquitination 0.3548852953208268 0.2866942928539747 0.7743464078811035 1.0 0.9978493338197336 14 Q96FW1 1 +Negative regulation of proteasomal protein catabolic process 0.3261454891002637 0.2850288011805276 0.7756220765768767 1.0 0.9987060536177976 20 O00560,Q86UE8 2 +Female sex differentiation 0.3543687854910884 0.2837816533741612 0.7765777152545248 1.0 0.9990543540251676 14 O94813,P98164 2 +Axis specification 0.3676027538704647 0.2836680755436944 0.7766647621568352 1.0 0.9990543540251676 10 Q9Y2W6 1 +Cell projection organization 0.3769615816501859 0.2834145180229953 0.7768591006628314 1.0 0.9991056704150808 236 P20339,Q86VR2,Q16625,P05556,Q12834,O00592,P62820,Q15154,A0AVF1,Q13277,O14786,P05067,Q96PU5,P48681,P04062,Q15375,Q9P273,P19022,P98155,O00560,P42345,A6NIH7,P08069,O15511,Q9Y5Y2,P07942,Q9NQX7,Q9NQC3,Q13641,Q9BZG1,Q9UQB8,P98164,Q99538,Q06481,Q04656,Q96G23,O94813,Q9HCE1,Q14108,Q92581,O00264,Q92692,Q15691,P61421,O15031,P35613,Q9H223,P42892,P10586,P00374,Q9H4M9,Q9NV96,O75955,Q15555,Q13308,Q4KMQ2,P07196,Q9Y277,P11233 59 +Regulation of neurotransmitter transport 0.3584248449606809 0.2830131952997422 0.7771667219676446 1.0 0.9993026285845146 13 P20339,Q15042,P16615,O75955,P05556,P0DP25 6 +Regulation of lipoprotein particle clearance 0.4057606734209414 0.2826957310806917 0.7774100889296376 1.0 0.9994169048660224 7 P01130 1 +Pallium development 0.3407383926333652 0.2824549208302666 0.7775947077960539 1.0 0.999455625816148 41 O14949,O94901,Q96QD8,P19022,Q96N66,P00533,O94813,P11166,P07196,P07942,Q9NQC3 11 +Mitochondrial outer membrane permeabilization involved in programmed cell death 0.3669885820416929 0.2806026365268856 0.7790151935950911 1.0 1.0 10 P45880 1 +Dendritic transport 0.4416010498687718 0.2805853798761518 0.7790284309105173 1.0 1.0 5 Q14254,Q00839,P23246,Q00577 4 +Regulation of peptidyl serine phosphorylation 0.3329676140136332 0.2804424186451635 0.7791380967702779 1.0 1.0 26 P05067 1 +Regulation of histone h2b ubiquitination 0.5439344262295136 0.2789454675314304 0.7802866747744417 1.0 1.0 3 O75150,Q6PD62 2 +Activation of immune response 0.335427644153657 0.2781227178979464 0.7809181570936317 1.0 1.0 52 P04439,Q06481,Q07021,Q08722,Q7KYR7,P15529,Q9NUD5,Q5ZPR3 8 +Acylglycerol homeostasis 0.543595981637645 0.2780482880753078 0.7809752911045476 1.0 1.0 3 Q8WTV0 1 +Positive regulation of fibroblast proliferation 0.4043696857492099 0.2768128464870177 0.7819238164165263 1.0 1.0 7 P14174,P00533 2 +Genitalia development 0.4136817831384534 0.2745754821114782 0.7836424050182382 1.0 1.0 6 P98164 1 +Dorsal ventral pattern formation 0.438622019213669 0.270069679711762 0.7871066477414936 1.0 1.0 5 O75386 1 +Regulation of meiotic cell cycle 0.4386034297737417 0.2700044096079413 0.7871568611828885 1.0 1.0 5 Q12834 1 +Response to extracellular stimulus 0.2752956226700436 0.2693196525783703 0.7876837101395533 1.0 1.0 85 Q96QD8,Q9Y4P8,P80303,P09601,P04062,P56192,P02786,P42345,P35610,P08069,O95831,Q92673,P01130,P20020,Q06481,Q02487,P04899,Q9H773,P21964,Q96C86,Q9HB90,P11166,P16435,Q9Y4P3 24 +Demethylation 0.3416326550961944 0.268362857806806 0.7884200263943106 1.0 1.0 16 P16435,Q8IUF8,Q16850,Q9Y2K7 4 +Positive regulation of endothelial cell migration 0.3235453779900614 0.2673569619689223 0.7891943330158377 1.0 1.0 20 Q99538,Q8WTV0,Q13685,P09601 4 +Coronary vasculature morphogenesis 0.4624818668985793 0.2666145711011662 0.7897659355083777 1.0 1.0 4 P98164 1 +Coronary artery morphogenesis 0.4624818668985793 0.2666145711011662 0.7897659355083777 1.0 1.0 4 P98164 1 +Positive regulation of plasma membrane bounded cell projection assembly 0.3297904800273064 0.2656120461661609 0.7905380072641695 1.0 1.0 25 P11233,Q04656,Q15555,Q16625 4 +Response to gamma radiation 0.3349208006997001 0.2632350589619548 0.792369410238958 1.0 1.0 17 Q86UE8 1 +Interleukin 6 mediated signaling pathway 0.537704918032788 0.2626415370904635 0.7928268816642976 1.0 1.0 3 Q13546,Q6PD62 2 +Growth hormone receptor signaling pathway via jak stat 0.5377049180327823 0.2626415370904485 0.7928268816643091 1.0 1.0 3 P18031,P07948 2 +Endoderm development 0.357855921677349 0.2610781548858007 0.7940322374935143 1.0 1.0 12 P06756 1 +Positive regulation of filopodium assembly 0.4097501160141897 0.2589202972668417 0.7956967371207706 1.0 1.0 6 P11233 1 +Regulation of erad pathway 0.4097246565742398 0.258819588699322 0.7957744431382192 1.0 1.0 6 Q4ZIN3 1 +Nucleus localization 0.3534199292496909 0.2559097570724521 0.7980205203873776 1.0 1.0 13 O94901,Q5SNT2,Q15154 3 +Cellular pigmentation 0.3869568201751979 0.2554959197547329 0.7983400946287316 1.0 1.0 8 P62820,Q13561 2 +Neurogenesis 0.3855456651835838 0.2535793026984662 0.7998205881441676 1.0 1.0 258 O94901,Q96N66,Q86VR2,P05556,Q9P2K5,Q9Y6M7,Q12834,Q15154,P15260,Q13277,O14786,P05067,Q96PU5,P54802,P04062,Q15375,Q9P273,P19022,P98155,Q8NHS3,P42345,P50897,Q92673,P07942,Q9NQX7,Q9NQC3,P01130,Q13641,O14949,Q9H0H5,P98164,Q06481,Q04656,Q96G23,Q92542,P07686,O94813,Q9HCE1,Q14108,P55209,Q92581,O00264,Q9NZJ7,O15031,P35613,P00374,P42892,P10586,O75503,O75386,Q9NV96,O75955,Q15555,Q07954,Q8NBN7,Q16739,P07196,Q9H4M9,P31751 59 +Centriole assembly 0.3609914917319795 0.2509587289409589 0.8018460177649454 1.0 1.0 10 P41208,Q9C0F1 2 +Regulation of muscle contraction 0.3379315231710724 0.2463250262357745 0.8054306385320438 1.0 1.0 16 P17612,P16615,P05023,Q14126,P0DP25,P20020 6 +Regulation of system process 0.3301444483719983 0.2461445481009938 0.805570339262411 1.0 1.0 54 P04062,O75844,Q9UQB8,P17612,P42892,P05023,P53634,P16615,Q02487,Q14126,P10253,P0DP25,P05067,P20020 14 +Phospholipid metabolic process 0.3097440315834671 0.2456392162273307 0.8059615289659048 1.0 1.0 68 Q92484,Q96N66,Q8WTV0,Q8NCC3,Q9UG56,Q8NHP8,P07686,Q9NRX5,Q9NX62,O43292,Q9BTU6,Q9NPH0,O14735,Q92643,O15269,P35790,Q9H490,P01130 18 +Negative regulation of bicellular tight junction assembly 0.5922648312028759 0.2454718768145193 0.8060910811861444 1.0 1.0 2 O75116 1 +Negative regulation of myosin light chain phosphatase activity 0.5922648312028759 0.2454718768145193 0.8060910811861444 1.0 1.0 2 O75116 1 +Cellular response to retinoic acid 0.3967706035083546 0.2451299623604803 0.806355803907473 1.0 1.0 7 Q9P0J0 1 +Apoptotic mitochondrial changes 0.3308415172198856 0.2448059099671288 0.8066067176460265 1.0 1.0 29 P52789,Q9H3K2,P12235,P45880,Q96A26,O60313 6 +Positive regulation of ion transport 0.3342126708085672 0.2443502992503517 0.8069595306448638 1.0 1.0 34 P54709,P51809,P55011,Q15042,O76024,Q4KMQ2,P0DP25,P20020 8 +Cellular response to mechanical stimulus 0.3511460364788659 0.2437318438177105 0.8074385091596696 1.0 1.0 13 Q9Y624,Q96QD8,P11166 3 +Gastrulation 0.3286334354203312 0.2424223639755823 0.8084529071587601 1.0 1.0 27 P10644,P06756,P09622,P05556,P07942 5 +Fertilization 0.3339152956020323 0.2421177370480985 0.8086889348406645 1.0 1.0 34 P45880,Q9Y2W6,P07686,P15529,P04114 5 +Positive regulation of myoblast fusion 0.4542852800028931 0.2420637596097481 0.808730758861389 1.0 1.0 4 O75955 1 +Regulation of myoblast fusion 0.4542852800028931 0.2420637596097481 0.808730758861389 1.0 1.0 4 O75955 1 +Regulation of syncytium formation by plasma membrane fusion 0.4542852800028931 0.2420637596097481 0.808730758861389 1.0 1.0 4 O75955 1 +Positive regulation of syncytium formation by plasma membrane fusion 0.4542852800028931 0.2420637596097481 0.808730758861389 1.0 1.0 4 O75955 1 +Negative regulation of response to wounding 0.4053986212199489 0.2418350016940987 0.8089080163124232 1.0 1.0 6 Q96G23 1 +Regulation of myotube differentiation 0.5294257830980241 0.2416729500793498 0.8090335910434805 1.0 1.0 3 P42345 1 +Anterior posterior pattern specification 0.3181464279976095 0.2413787363970456 0.8092615914909143 1.0 1.0 19 Q15363,O75787,Q9Y2W6 3 +Erk1 and erk2 cascade 0.335280331791812 0.2413010702123653 0.8093217814852649 1.0 1.0 38 Q15375,P06756,P00533,P05067,Q13641,Q96P70 6 +Box c d snornp assembly 0.4539598842509564 0.2411065577518545 0.8094725303389139 1.0 1.0 4 P55769 1 +Small nucleolar ribonucleoprotein complex assembly 0.4539598842509564 0.2411065577518545 0.8094725303389139 1.0 1.0 4 P55769 1 +Vesicle docking involved in exocytosis 0.383650743981854 0.2410576979914222 0.809510398190679 1.0 1.0 8 O00186,P11234,P61026,Q7Z6M1 4 +Regulation of cilium assembly 0.3420478153634353 0.2403857824023281 0.8100311991186435 1.0 1.0 15 Q15555 1 +Regulation of cell growth involved in cardiac muscle cell development 0.5288524590163983 0.2402510124517667 0.8101356692739556 1.0 1.0 3 P49840,P11413 2 +Negative regulation of cardiac muscle tissue growth 0.5288524590163983 0.2402510124517667 0.8101356692739556 1.0 1.0 3 P49840,P11413 2 +Negative regulation of cell growth involved in cardiac muscle cell development 0.5288524590163983 0.2402510124517667 0.8101356692739556 1.0 1.0 3 P49840,P11413 2 +Ribonucleoprotein complex disassembly 0.4297900262467169 0.2395612118273478 0.8106704376777505 1.0 1.0 5 P55072,P33176,Q14562,Q9UBB9 4 +Quaternary ammonium group transport 0.5277765285575862 0.2375931835625483 0.8121966378767345 1.0 1.0 3 Q96QD8 1 +N terminal peptidyl methionine acetylation 0.5883316945263762 0.2365313053039318 0.8130204182114651 1.0 1.0 2 Q14CX7 1 +Mesoderm development 0.3529575120327607 0.2356750839115857 0.8136848054950638 1.0 1.0 12 P10644,P05556 2 +Cellular lipid metabolic process 0.3523435998976535 0.2347674918982329 0.8143892003278101 1.0 1.0 198 O75844,Q6IAA8,P61916,Q96N66,A1L0T0,Q9BT22,Q9HB40,P04114,O95470,Q99519,Q9BTU6,P07602,Q2TAA5,Q99805,P04062,Q8NCC3,P04066,Q9UG56,P06280,Q9NRX5,Q9NPH0,P50897,Q92673,Q99735,Q9H490,P01130,P19021,Q13510,Q92484,P98164,P16278,P06865,Q06481,Q06136,Q96G23,Q15800,Q8NHP8,Q8TCT0,P07686,O14735,Q9H2C2,P17900,P35790,Q92643,P23786,P27544,Q9NZJ7,Q6NUM9,Q8NBX0,Q8WTV0,Q9BV10,Q9P035,Q9NX62,O43292,Q07954,P16435,Q8NBN7,P51648,Q16739,O15269,Q9NZ01,P31751 62 +Regulation of cholesterol efflux 0.4516315799500223 0.2342971183027164 0.8147543229325602 1.0 1.0 4 Q07954 1 +Regulation of membrane tubulation 0.5870206489675431 0.2335953293428894 0.8152991540889847 1.0 1.0 2 P50570 1 +Camera type eye morphogenesis 0.3800528447453044 0.2255279336984681 0.8215685970998128 1.0 1.0 8 P54802,Q8NBN7,Q9P273,Q15555 4 +Attachment of spindle microtubules to kinetochore 0.3281078100896293 0.2214754651634109 0.8247222382397204 1.0 1.0 17 Q9H0H5,Q15005,Q8NBT2,Q96DB5,Q9BZD4 5 +Mapk cascade 0.281465893001059 0.2212122285522101 0.8249271881041405 1.0 1.0 97 Q6IAA8,O75915,Q96J02,O14786,P05067,Q96P70,P04062,Q15375,P19022,Q53EL6,O00560,P08069,Q92673,Q13641,Q969S3,P06756,O75787,P00533,Q14596,Q9P035,P78318,P57105 22 +Regulation of modification of postsynaptic structure 0.4463981729225243 0.2192486284201582 0.8264563768512394 1.0 1.0 4 Q9UQB8 1 +Regulation of modification of synaptic structure 0.4463981729225243 0.2192486284201582 0.8264563768512394 1.0 1.0 4 Q9UQB8 1 +Negative regulation of peptidase activity 0.3323188327892118 0.2166644502217289 0.8284698545020808 1.0 1.0 39 Q06481,P07858,P05067,Q92673 4 +Positive regulation of production of molecular mediator of immune response 0.3187911285706589 0.2160135899477961 0.8289771543936952 1.0 1.0 22 P02786 1 +Positive regulation of dopamine receptor signaling pathway 0.5788266142248484 0.2157504209011979 0.8291822964533146 1.0 1.0 2 O14744 1 +Regulation of dopamine receptor signaling pathway 0.5788266142248484 0.2157504209011979 0.8291822964533146 1.0 1.0 2 O14744 1 +Morphogenesis of an endothelium 0.5170491803278721 0.2118644012017369 0.8322128238499735 1.0 1.0 3 P35222,P67870 2 +Lamellipodium organization 0.324041381057363 0.2101943862865954 0.8335159607937139 1.0 1.0 27 Q16625,P05556,Q04656,P42345,O94813 5 +Positive regulation of transmembrane transport 0.3259515854071459 0.2098870403541446 0.8337558372491951 1.0 1.0 29 P54709,Q16625,Q4KMQ2,P0DP25,P31751 5 +Regulation of heart rate 0.3523964677845106 0.2094470681956078 0.8340992523602313 1.0 1.0 10 Q14126,P16615,P17612,P0DP25 4 +Axonal transport of mitochondrion 0.420659205133425 0.209124134337458 0.8343513347406406 1.0 1.0 5 O60313 1 +Postsynaptic actin cytoskeleton organization 0.5131147540983693 0.2027846388865151 0.8393033648844646 1.0 1.0 3 Q9UJU6,Q16352 2 +Negative regulation of exocytosis 0.3860836860001418 0.2019637058206939 0.8399450980235783 1.0 1.0 7 P51149,P04899,P09601 3 +Homeostatic process 0.3944317722306983 0.2013878871523114 0.8403952858419981 1.0 1.0 287 Q13501,P62942,P05556,P36896,P05067,Q96TC7,Q8NEW0,P17612,P02786,O95067,Q15067,P42785,P35610,P50897,Q9NQC3,O00115,Q9P0T7,Q06481,Q7L0J3,P10253,O75503,P09622,O14773,Q16739,Q9HC07,Q16625,P09601,Q9UIQ6,P04114,P30519,O15118,Q93050,Q9HD20,P01130,P06756,P16615,Q04656,Q92542,P07686,Q15904,Q8NE01,Q92581,O15260,Q15555,P51790,P11166,Q4KMQ2,O95202,P52789,P61916,P39210,Q8N511,P04920,Q96A33,Q96PU5,P04062,P14672,P0DP25,Q9Y6B6,Q92544,O75787,P38571,P23786,Q9Y624,P54105,Q8WTV0,Q9Y487,O76024,Q9H4M9,Q6IAA8,P55011,P05023,P05141,Q9Y6M7,Q9Y6C9,Q9NX40,Q15043,Q16891,P19022,Q8IYU8,Q9BPX6,P20020,Q9P0S9,Q14964,P54709,Q9P035,Q9BWH2,P51149 88 +Regulation of protein secretion 0.3277725380159948 0.2008378654075731 0.8408253538068917 1.0 1.0 33 P49755,P55011,Q9H4A5,Q16850,O00429,Q96KC8,P19021 7 +Erbb signaling pathway 0.3191762109211651 0.2006776187293405 0.8409506613646962 1.0 1.0 24 Q99538,Q9NQC3,P00533 3 +Regulation of carbohydrate catabolic process 0.3391593103706823 0.2000773133655247 0.8414201159358619 1.0 1.0 14 P05067 1 +Negative regulation of inflammatory response 0.3623133856350869 0.2000604299974314 0.8414333199894373 1.0 1.0 9 P01130 1 +Regulation of innate immune response 0.3296978043792815 0.1967300280249883 0.8440388103067269 1.0 1.0 45 P11279,P04439,Q06481,Q9NZ08,Q9NUD5 5 +Muscle cell proliferation 0.3185727680391529 0.1966035842185365 0.8441377655561688 1.0 1.0 24 P10644,Q14344,Q53EL6,P09601,P08754,P08069,P04899 7 +Positive regulation of lamellipodium organization 0.3342282988781324 0.1964581652061431 0.8442515738921248 1.0 1.0 15 Q16625 1 +Netrin activated signaling pathway 0.5689937725335864 0.1954966297508105 0.8450041758499118 1.0 1.0 2 A0MZ66 1 +Negative regulation of perk mediated unfolded protein response 0.567354965585056 0.1922449707878015 0.8475503212201965 1.0 1.0 2 P18031 1 +Regeneration 0.3241175098341737 0.1906409277056754 0.8488069225395614 1.0 1.0 30 Q96G23,P09601,P11717 3 +Response to cadmium ion 0.3330666052687653 0.1900377019885834 0.8492795869077274 1.0 1.0 15 Q04656,O15118,P09601 3 +Long chain fatty acid biosynthetic process 0.5660439200262116 0.1896692371566892 0.8495683283843432 1.0 1.0 2 O00154 1 +Positive regulation of endoplasmic reticulum unfolded protein response 0.5071609324207946 0.1894154482807184 0.8497672176506927 1.0 1.0 3 P57088 1 +Positive regulation of ire1 mediated unfolded protein response 0.5071609324207946 0.1894154482807184 0.8497672176506927 1.0 1.0 3 P57088 1 +Cellular response to glucose starvation 0.3476045099457078 0.1868419250423367 0.8517845742691834 1.0 1.0 10 P11166 1 +Sphingomyelin metabolic process 0.3821867949034284 0.186656650268857 0.8519298467247161 1.0 1.0 7 O15269 1 +Epithelial structure maintenance 0.5644051130776787 0.1864815918064032 0.8520671132693574 1.0 1.0 2 P78310 1 +Positive regulation of neurogenesis 0.3282270459049599 0.1849994881076368 0.8532294370744702 1.0 1.0 39 O15031,P98164,Q9UQB8,P42345,O94813,P55209,P07196,O14786 8 +Adhesion of symbiont to host 0.4338245675802197 0.1845982466376279 0.8535441612889825 1.0 1.0 4 Q8WTV0 1 +Neutrophil mediated immunity 0.5047375724728699 0.1841029882997367 0.8539326622267267 1.0 1.0 3 P51809 1 +Organelle localization 0.3344014127781494 0.1838291481719151 0.8541474888604776 1.0 1.0 175 O43633,O94901,Q6IAA8,P09601,O60499,Q5SNT2,P05556,Q96D46,Q86YV9,Q15154,P62820,O00743,Q13277,Q9NR31,Q9BZD4,Q92572,P19022,O00186,O75153,O15400,O00560,P42345,P14672,Q14849,Q8WWQ0,Q9Y6B6,Q9UNK0,Q9BZG1,Q7Z6M1,P16615,Q96A57,Q6PJG6,Q8IWA4,Q9HCU5,Q92692,P49755,Q13190,O75381,P51809,Q8WUM4,O00429,Q96DB5,Q15363,O60313,Q86Y82,Q13561,P07196,P11279,P51149,O95772 50 +Cdp diacylglycerol metabolic process 0.4332794292653418 0.1831453703508869 0.8546839573801721 1.0 1.0 4 O14735,O95674 2 +Positive regulation of wnt signaling pathway 0.3137052336289747 0.1822367259446075 0.8553969523960208 1.0 1.0 22 Q9P0T7,O75787,Q96K76,P00533,Q9BZK7 5 +Regulation of cell division 0.3199874071462604 0.1821546032750227 0.8554613982318835 1.0 1.0 27 Q9H0H5,O43663,P08069,P41208,P0DP25,Q16513 6 +Negative regulation of dendrite morphogenesis 0.5026229508196771 0.179528853725004 0.8575224633611995 1.0 1.0 3 Q04917,Q9Y4G8 2 +Digestive system development 0.3690012107310525 0.1790922041773434 0.8578653032116073 1.0 1.0 8 P04920 1 +Body morphogenesis 0.3571815230490863 0.1774380325440755 0.85916433559983 1.0 1.0 9 O75787,Q15042 2 +Superoxide metabolic process 0.3571138148844269 0.1771426245051013 0.859396361800016 1.0 1.0 9 P04899,P00374,Q04656 3 +Cellular response to ether 0.5594886922320469 0.177132390009249 0.8594044006317008 1.0 1.0 2 Q6PKG0 1 +Neurotransmitter receptor transport endosome to postsynaptic membrane 0.5588331694526297 0.1759100717177046 0.860364592654393 1.0 1.0 2 Q96QK1 1 +Regulation of cardiac muscle cell action potential 0.3793730459381705 0.1757555931482571 0.8604859580060635 1.0 1.0 7 Q14126,P16615 2 +Regulation of myosin light chain phosphatase activity 0.5006557377049179 0.1753252737289778 0.8608240537719734 1.0 1.0 3 O14920,O75116 2 +Regulation of cardiac muscle contraction 0.356112637408196 0.1727840385020282 0.8628211837668858 1.0 1.0 9 Q14126,P16615,P17612,P0DP25 4 +Oxidative demethylation 0.556866601114383 0.1722773557297542 0.8632194856939117 1.0 1.0 2 Q9C0B1 1 +Oxidative rna demethylation 0.556866601114383 0.1722773557297542 0.8632194856939117 1.0 1.0 2 Q9C0B1 1 +Programmed necrotic cell death 0.3296175915179158 0.1711458614013011 0.8641090756294572 1.0 1.0 15 P12235 1 +Cellular process involved in reproduction in multicellular organism 0.324633843657956 0.1705715051555156 0.8645607051189836 1.0 1.0 50 P17612,O95067,Q9Y2W6,P05556,Q92692,P09622,P42345,P07686,O94813,A0AVF1 10 +Regulation of protein catabolic process 0.2989966119763136 0.1690897389336873 0.8657260558609745 1.0 1.0 125 P61289,P10619,Q9P0J0,Q96J02,Q4ZIN3,Q96PU5,P04062,Q8NHS3,P53634,O00560,Q92673,Q86UE8,P01130,Q9P0T7,P98164,P00533,Q96HY6,Q13190,Q07954 19 +Negative regulation of telomerase activity 0.4273243945473 0.1675489615926002 0.8669381261805527 1.0 1.0 4 P27544 1 +Telencephalon development 0.3263393725632416 0.167423565435849 0.8670367843264026 1.0 1.0 43 O14949,O94901,Q96QD8,P19022,Q96N66,P00533,O94813,P11166,P07196,P07942,Q9NQC3 11 +Signal release 0.3258852675705573 0.1674174068921917 0.8670416297475616 1.0 1.0 46 P20339,P51809,Q15042,P16870,P16615,Q7L0J3,P62820,P50897,P0DP25,Q13277 10 +Negative regulation of cation channel activity 0.3854869254274372 0.1671720777885993 0.8672346539280633 1.0 1.0 6 P0DP25 1 +Peptidyl serine modification 0.3076363400730521 0.1655773639322874 0.8684895623384712 1.0 1.0 65 Q9BV86,P02786,Q10471,Q10472,Q86UE8,P05067,P31751 7 +Regulation of wound healing 0.323828465460686 0.1648910868614992 0.8690297080250358 1.0 1.0 16 P55011,Q16625,P05556,Q4KMQ2,Q9Y251 5 +Protein containing complex localization 0.3254897759443108 0.1640427531915267 0.8696974874864412 1.0 1.0 39 O15400,Q96D46,Q13277 3 +Positive regulation of membrane permeability 0.3409652404895651 0.1640251465338623 0.8697113478356084 1.0 1.0 11 P45880 1 +Regulation of membrane protein ectodomain proteolysis 0.4940983606557371 0.1616755061469189 0.871561394011354 1.0 1.0 3 Q9UKS6,O43847 2 +Positive regulation of membrane protein ectodomain proteolysis 0.4940983606557371 0.1616755061469189 0.871561394011354 1.0 1.0 3 Q9UKS6,O43847 2 +Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.353350790742738 0.1608539999452667 0.8722083931390745 1.0 1.0 9 O76024,O60313 2 +Endoplasmic reticulum to cytosol transport 0.3402879577584699 0.1608280913972551 0.8722287995003537 1.0 1.0 11 P51572,Q9BUN8,Q9UBV2,Q8TCT9 4 +Humoral immune response 0.3377328374169447 0.1594355971108836 0.8733256951512558 1.0 1.0 12 P15529,P04439 2 +Regulation of camp mediated signaling 0.5496558505407964 0.1593967001408814 0.8733563385801806 1.0 1.0 2 P63096 1 +Extrinsic apoptotic signaling pathway 0.3250050320596918 0.1573533326113972 0.8749663903786697 1.0 1.0 44 P61289,P06756,P09601,P36896,Q99523,Q9P0J0,Q9NQX7,O14786 8 +Negative regulation of cytokine production 0.3151992575610861 0.1573485828008535 0.8749701335519304 1.0 1.0 26 P04062,P09601,Q06481,Q07021,Q96J02 5 +Regulation of protein localization to centrosome 0.4908196721311483 0.1550608626438563 0.876773336021659 1.0 1.0 3 P25054,Q9UNZ2 2 +Regulation of signaling receptor activity 0.3304288107790326 0.1540492827651595 0.8775708773012105 1.0 1.0 14 O14786,P05067 2 +Response to oxygen radical 0.4029045141595716 0.1534114676319126 0.878073802072187 1.0 1.0 5 Q04656 1 +Cellular response to oxygen radical 0.4029045141595716 0.1534114676319126 0.878073802072187 1.0 1.0 5 Q04656 1 +Interstrand cross link repair 0.4026518860225889 0.1526536263268162 0.8786714328575322 1.0 1.0 5 Q9BXW9 1 +Negative regulation of cell cell adhesion 0.3059368806094287 0.1517509185947811 0.8793833949620748 1.0 1.0 20 P10644,O00592 2 +Dendritic cell apoptotic process 0.5447394296951721 0.1510096575553392 0.8799680976383719 1.0 1.0 2 Q9Y4G8 1 +Vesicle transport along microtubule 0.3381309519429427 0.1507066954099646 0.8802070913914544 1.0 1.0 11 P62820 1 +Regulation of lipid kinase activity 0.4019028871391039 0.1504127056891452 0.8804390176188301 1.0 1.0 5 Q05639,Q05397,P07948,A4D1P6 4 +Establishment of protein localization to plasma membrane 0.3086768285205844 0.1494975764092705 0.88116102162375 1.0 1.0 22 Q9BZG1,Q9H4A5,Q15904,Q9HD26,P51149,Q4J6C6 6 +Negative regulation of biomineralization 0.5414618157980915 0.1455957733224596 0.8842405048291186 1.0 1.0 2 O75116 1 +Cellular glucose homeostasis 0.3080168412273356 0.145251771043757 0.8845120919261364 1.0 1.0 22 P62995,P52789,Q99808,P17612,O00186,Q9NWS0,P08069,Q15043 8 +Defense response to symbiont 0.3180826713276479 0.1445316892580191 0.8850806347375846 1.0 1.0 55 Q9NVI7,O75844,Q96J02,Q07021,Q9HCE1,O43657,P15260,Q9NUD5 8 +Regulation of superoxide anion generation 0.4180382655812151 0.1442523969748754 0.885301166770077 1.0 1.0 4 P04899 1 +Response to tumor necrosis factor 0.3214555282615803 0.1422564610730711 0.8868774357242919 1.0 1.0 36 P04114,Q8TCT8,P14672,P04062 4 +Anaphase promoting complex dependent catabolic process 0.3375400026451278 0.140737137509182 0.8880776055798116 1.0 1.0 10 P30260,Q9UJX4,Q9UJX3,P53350,Q12834 5 +Spermatid differentiation 0.30570739478152 0.1402262529130886 0.8884812300065121 1.0 1.0 21 A0AVF1,P09622,Q92692 3 +Positive regulation of cytokine production involved in inflammatory response 0.5375286791215895 0.1392858221252768 0.8892242929759673 1.0 1.0 2 O60684 1 +Hippo signaling 0.4158740570678865 0.1390058130136015 0.8894455555268019 1.0 1.0 4 Q4VCS5,Q01085,Q13043 3 +Positive regulation of aspartic type peptidase activity 0.4819672131147531 0.1379068901763067 0.8903140048702969 1.0 1.0 3 P07948,O75116 2 +Protein peptidyl prolyl isomerization 0.3068093047068887 0.1375154003953293 0.8906234206303105 1.0 1.0 22 O95302,Q9NWM8,Q9Y680 3 +Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis 0.5355621107833402 0.1362069527764869 0.8916576788742485 1.0 1.0 2 Q13177 1 +Meiotic sister chromatid cohesion centromeric 0.5352343493936311 0.1356987269244597 0.8920594541789577 1.0 1.0 2 O60566 1 +R loop disassembly 0.4142341751393854 0.1350769817795468 0.8925510092449402 1.0 1.0 4 P78362,Q9BUQ8,Q9NY93 3 +Locomotory exploration behavior 0.5322844968862603 0.1311877724201195 0.8956267685548551 1.0 1.0 2 Q15334 1 +Regulation of gene silencing by rna 0.3008461554408882 0.1302903456899988 0.8963367179853698 1.0 1.0 19 O75844 1 +Negative regulation of nf kappab transcription factor activity 0.321844015381264 0.1295519404269546 0.8969209286729136 1.0 1.0 15 Q86VP1 1 +Cell junction assembly 0.296799031801827 0.125540900088839 0.900095347556682 1.0 1.0 69 Q9Y624,Q15375,O15031,Q16625,O75955,O00560,O14786,P05067,Q13641 9 +Postsynaptic membrane organization 0.3735683419327644 0.1255199920823992 0.9001118988106886 1.0 1.0 6 P19022 1 +Positive regulation of glial cell proliferation 0.5283513602097571 0.1253490764814399 0.9002472011206588 1.0 1.0 2 P07948 1 +Gdp metabolic process 0.4750819672131113 0.1252806057168323 0.9003014056028662 1.0 1.0 3 Q00013,Q14168 2 +Negative regulation of cell morphogenesis involved in differentiation 0.4747540983606552 0.1246950173370898 0.9007650022021056 1.0 1.0 3 Q9P258,O43707 2 +Negative regulation of retinoic acid receptor signaling pathway 0.527040314650928 0.1234472975387588 0.9017529054449276 1.0 1.0 2 A5YKK6 1 +Response to lithium ion 0.5270403146509255 0.1234472975387551 0.9017529054449304 1.0 1.0 2 Q13144 1 +Positive regulation of small molecule metabolic process 0.3274909135122271 0.1228394791235363 0.9022342111661874 1.0 1.0 13 P16435,P05067,P31751,P00403 4 +Regulation of release of sequestered calcium ion into cytosol 0.3334478575455601 0.1225601135583879 0.9024554410187012 1.0 1.0 10 P62942,P0DP25 2 +Regulation of calcium ion transport into cytosol 0.3334478575455601 0.1225601135583879 0.9024554410187012 1.0 1.0 10 P62942,P0DP25 2 +Germ cell development 0.3190799899330604 0.1214134412994975 0.903363571023168 1.0 1.0 37 P17612,Q9Y2W6,P09622,Q92692,P07686,A0AVF1 6 +Signal complex assembly 0.4704918032786923 0.1172120300266968 0.906692034050425 1.0 1.0 3 P16333,Q05397 2 +Cellular response to extracellular stimulus 0.3194694335790005 0.1171175196300674 0.9067669266214567 1.0 1.0 47 P04062,Q96QD8,P56192,P21964,P09601,Q9Y4P8,Q96C86,Q9HB90,P42345,O95831,Q02487,P11166,Q9Y4P3,P20020 14 +Xenobiotic metabolic process 0.328141466527368 0.1137831643797943 0.9094096847883736 1.0 1.0 12 P16435,O43169 2 +Negative regulation of jnk cascade 0.3890711743276067 0.113434385021942 0.9096861803241398 1.0 1.0 5 Q96J02 1 +Positive regulation of reactive oxygen species biosynthetic process 0.4044685231487547 0.1125234707766309 0.910408360930192 1.0 1.0 4 P51790 1 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.3884514435695522 0.1117174905317186 0.911047410708526 1.0 1.0 5 P25054,P53350,O00410,O95373 4 +Regulation of cysteine type endopeptidase activity 0.3171447605919582 0.111259268644689 0.9114107537281144 1.0 1.0 51 Q15392,Q15375,Q9NR28,Q9BXK5,Q99538,Q96A26,O75915,O95831,Q9P0J0,P78318,P16435,Q9NZJ7 12 +Substantia nigra development 0.3137965097135406 0.1097588063273286 0.912600661383034 1.0 1.0 16 P60953,P61586,P24539,P27348,O75489,P62258,Q04917,P00367,P12277,P09543,Q16352,P63167,P11413,P0DP25,O15027 15 +Positive regulation of smooth muscle contraction 0.5168797115699677 0.1094538115893911 0.912842554604661 1.0 1.0 2 Q14247 1 +Membrane depolarization during action potential 0.5165519501802578 0.1090241787016936 0.9131833128116024 1.0 1.0 2 Q04917 1 +Response to dexamethasone 0.3300860321445678 0.1078879732602179 0.914084557381308 1.0 1.0 10 P04062,P16435,Q9H7B4 3 +Negative regulation of mrna 3 end processing 0.3682310469314007 0.1076725211428847 0.9142554677135482 1.0 1.0 6 Q6PJT7,O75150,Q6PD62,P50750,P18615 5 +Regulation of phosphatase activity 0.2987690711954022 0.1070522164238386 0.9147475550097344 1.0 1.0 20 Q15257,P62942,P42345,P04899,P0DP25 5 +Muscle cell differentiation 0.3062887110506402 0.1070265893124326 0.9147678856833434 1.0 1.0 62 P10644,O75844,P19022,Q53EL6,P16615,P05556,O75955,Q9P2K5,Q8IV08,Q99523,Q9H4M9,Q16527,Q9H7B4 13 +Regulation of phosphatidylinositol 3 kinase activity 0.4017710724827771 0.1065510635903009 0.9151451430734046 1.0 1.0 4 Q05397,P07948,A4D1P6 3 +Cytoplasmic sequestering of nf kappab 0.4014430960970814 0.1058325544989046 0.9157152070730884 1.0 1.0 4 Q9UNN5,O60826,Q9UN86 3 +Response to vitamin d 0.3861548556430551 0.1054117492357665 0.916049093464413 1.0 1.0 5 Q8TB36,Q14258,P20020,Q15648 4 +Negative regulation of establishment of protein localization to mitochondrion 0.4011151197113759 0.1051157098451075 0.9162839937105228 1.0 1.0 4 P49257,O95429,P31689 3 +Regulation of protein localization to chromatin 0.5126188135037584 0.1039733153714567 0.9171905250214848 1.0 1.0 2 Q7Z5K2 1 +Positive regulation of oligodendrocyte differentiation 0.4003784403356261 0.1035116525191206 0.9175569018005632 1.0 1.0 4 P42345 1 +Regulation of nk t cell differentiation 0.5116355293346332 0.1027406500585232 0.9181688102545318 1.0 1.0 2 O00203 1 +Antigen processing and presentation of lipid antigen via mhc class ib 0.5116355293346332 0.1027406500585232 0.9181688102545318 1.0 1.0 2 O00203 1 +Synaptic vesicle endosomal processing 0.5116355293346332 0.1027406500585232 0.9181688102545318 1.0 1.0 2 O00203 1 +Nk t cell differentiation 0.5116355293346332 0.1027406500585232 0.9181688102545318 1.0 1.0 2 O00203 1 +Synaptic vesicle recycling via endosome 0.5116355293346332 0.1027406500585232 0.9181688102545318 1.0 1.0 2 O00203 1 +Antigen processing and presentation via mhc class ib 0.5116355293346332 0.1027406500585232 0.9181688102545318 1.0 1.0 2 O00203 1 +Carbohydrate metabolic process 0.3040860980054548 0.1024667278400781 0.9183862211471712 1.0 1.0 139 P52789,O75844,Q8NBZ7,Q99519,Q7LGA3,P05067,Q9BRR6,P04066,P06280,P14672,O00754,P33908,P16278,P06865,P08195,P07686,Q9BTY2,Q14108,P17900,O43505,P10253,O00462,Q9UBX3,Q9NX62,P08236,P11166,P31751 27 +Response to aldosterone 0.3996458548029362 0.1019248518707133 0.9188163237459156 1.0 1.0 4 O95831 1 +Myeloid leukocyte mediated immunity 0.3227476688188453 0.1000395380074764 0.920312936082424 1.0 1.0 13 O00186,P51809,P09601 3 +Peptidyl arginine methylation 0.3657414776491037 0.0995250369492352 0.9207214099726716 1.0 1.0 6 Q7L592,Q6P2P2 2 +Peptidyl arginine n methylation 0.3657414776491037 0.0995250369492352 0.9207214099726716 1.0 1.0 6 Q7L592,Q6P2P2 2 +Smoothened signaling pathway 0.3114095588806117 0.0970242680781672 0.9227071222281298 1.0 1.0 16 Q9BZG1,P17612,O75386,P16435,A0AVF1 5 +Regulation of stress granule assembly 0.5050803015404672 0.0948262444991488 0.9244528407022188 1.0 1.0 2 Q13283 1 +Positive regulation of vacuole organization 0.3818522695358827 0.0938407039006444 0.925235697293764 1.0 1.0 5 Q15042 1 +Protein localization to cilium 0.3255064001038256 0.0934206310832472 0.9255694009559304 1.0 1.0 11 Q9UPT5,O75386,Q9H4M9,A0AVF1,P18085 5 +Cellular response to muramyl dipeptide 0.4554098360655773 0.0926635608367868 0.9261708466534222 1.0 1.0 3 Q92974,P08670 2 +Response to muramyl dipeptide 0.4554098360655773 0.0926635608367868 0.9261708466534222 1.0 1.0 3 Q92974,P08670 2 +Energy derivation by oxidation of organic compounds 0.2910245445227924 0.0921151561975592 0.9266065467458976 1.0 1.0 122 P13073,O75964,P14406,Q7KZN9,Q15070,Q9Y6M9,Q15526,P04062,Q9UDW1,P03886,O75438,P03915,O14949,Q9NZ45,Q13423,Q04656,O96000,P00403,O43676,P10253,P46020,Q9BSK2,O95169,Q9H3K2,P09622,P31751 26 +Regulation of trans synaptic signaling 0.3129754494499078 0.091915048073338 0.9267655354406904 1.0 1.0 54 P20339,Q13501,P55011,P19022,P17612,Q9UQB8,Q15042,Q99538,P05556,P16615,Q92542,O75955,Q12834,P04899,Q96A49,P0DP25,Q13277,P05067 18 +Connective tissue replacement 0.5024582104228071 0.0918064421272868 0.926851825603775 1.0 1.0 2 O75116 1 +Regulation of connective tissue replacement 0.5024582104228071 0.0918064421272868 0.926851825603775 1.0 1.0 2 O75116 1 +Positive regulation of connective tissue replacement 0.5024582104228071 0.0918064421272868 0.926851825603775 1.0 1.0 2 O75116 1 +Positive regulation of tissue remodeling 0.5024582104228071 0.0918064421272868 0.926851825603775 1.0 1.0 2 O75116 1 +Positive regulation of voltage gated calcium channel activity 0.5018026876433882 0.0910643635703484 0.9274414487028262 1.0 1.0 2 Q00535 1 +Positive regulation by host of viral transcription 0.3555482600131294 0.0889756130268128 0.9291012912205768 1.0 1.0 7 O14646,P51532,P50750,Q13573,Q12824,Q9H1E3 6 +Negative regulation of extrinsic apoptotic signaling pathway 0.2987241757109736 0.0868334419022488 0.9308039052144856 1.0 1.0 22 P61289,P06756,P09601 3 +Dsrna processing 0.2970446697250918 0.0863882655890472 0.9311577747609148 1.0 1.0 21 O75844,O75569,Q9UGR2,P00533 4 +Oligodendrocyte development 0.3248139882734452 0.0853722235404733 0.9319654749286584 1.0 1.0 10 Q13144,Q92542,P18074 3 +Activation induced cell death of t cells 0.4504918032786966 0.0853053781454854 0.9320186159790766 1.0 1.0 3 P62753,P31749 2 +Myoblast differentiation 0.3612736065375672 0.0851930619154098 0.9321079063191042 1.0 1.0 6 Q14254 1 +Leukotriene metabolic process 0.3905888204521371 0.0829978883439882 0.9338532186795274 1.0 1.0 4 Q99735,P09960 2 +Positive regulation of attachment of spindle microtubules to kinetochore 0.4488524590163976 0.082922718400469 0.9339129895786024 1.0 1.0 3 Q9P258,P14635 2 +Cleavage furrow formation 0.4939364142903859 0.082554942036224 0.9342054299631336 1.0 1.0 2 P61586 1 +Synapse maturation 0.3896662416072535 0.0811419848726022 0.9353290366489432 1.0 1.0 4 P07196 1 +Collagen biosynthetic process 0.3767183619405589 0.0804535969030426 0.9358765008506118 1.0 1.0 5 Q92791 1 +Negative regulation of dna binding transcription factor activity 0.3034146623678253 0.0802682939025288 0.9360238746233072 1.0 1.0 26 O75381,P09601,Q86VP1,O60826,O76024,Q96J02 6 +Gastrulation with mouth forming second 0.4468852459016364 0.0801095544034806 0.9361501238575068 1.0 1.0 3 P35222,Q99496 2 +Ensheathment of neurons 0.2990719477148035 0.0794848733270418 0.9366469628800522 1.0 1.0 23 P53634,Q92542,P07686 3 +Negative regulation of actin filament polymerization 0.2982271846880628 0.0793174731353842 0.9367801085346056 1.0 1.0 18 Q9NUQ9 1 +Positive regulation of protein localization to centrosome 0.4906588003933038 0.0792211550357143 0.9368567181875928 1.0 1.0 2 P25054 1 +Regulation of anoikis 0.3592073581277537 0.078692916834823 0.9372768795564556 1.0 1.0 6 P05556 1 +Regulation of dephosphorylation 0.3131271855256249 0.078407626668527 0.9375038070060469 1.0 1.0 37 P04062,Q15257,P62942,Q9UPR3,P42345,P78318,Q86XL3,P04899,P0DP25 9 +Sperm dna condensation 0.4886922320550591 0.0772794697002497 0.9384012228639252 1.0 1.0 2 Q96SB4 1 +Sugar mediated signaling pathway 0.3876680878976617 0.0771682623743452 0.938489689292701 1.0 1.0 4 P17480,Q9NWS0,Q12824 3 +Pteridine containing compound metabolic process 0.3029711403886284 0.0768294413983499 0.938759229104601 1.0 1.0 17 Q9H2D1,Q92820 2 +Regulation of torc2 signaling 0.4863979023270939 0.0750690099416345 0.9401598047135866 1.0 1.0 2 Q9NWS0 1 +Cellular response to vitamin d 0.3860282059691509 0.0739539642507612 0.94104701610563 1.0 1.0 4 Q8TB36,P20020,Q15648 3 +Toxin transport 0.3191224784399156 0.0727500181862417 0.9420050452100746 1.0 1.0 12 Q93050 1 +Regulation by virus of viral protein levels in host cell 0.3840315452173817 0.0700975310800101 0.9441160317832 1.0 1.0 4 Q9P035 1 +Cellular response to oxidised low density lipoprotein particle stimulus 0.480170435922644 0.0693614330172707 0.9447019269467768 1.0 1.0 2 Q5JRA6 1 +Negative regulation of lymphocyte migration 0.480170435922644 0.0693614330172707 0.9447019269467768 1.0 1.0 2 Q5JRA6 1 +Regulation of type b pancreatic cell development 0.4801704359226361 0.0693614330172637 0.9447019269467825 1.0 1.0 2 P49840 1 +Anion homeostasis 0.3833885614307123 0.0688690199259928 0.945093878467558 1.0 1.0 4 P55011 1 +Glycerophospholipid metabolic process 0.3120794029270159 0.0685935554376792 0.9453131488015802 1.0 1.0 51 Q96N66,Q8WTV0,Q8NCC3,Q9UG56,Q9NX62,O43292,Q9NRX5,Q9BTU6,Q9NPH0,O14735,Q92643,P35790,Q9H490,P01130 14 +Response to nutrient 0.3001725380537799 0.0683169047642134 0.9455333675115204 1.0 1.0 25 P02786,P09601,Q96C86,P42345,P08069,P16435,P20020 7 +Histone h4 deacetylation 0.3830764184978643 0.0682749769821474 0.9455667431131592 1.0 1.0 4 Q9UKL0,Q13547,Q9H4L7 3 +Histone h3 k9 dimethylation 0.478859390363803 0.0682132811763298 0.9456158547479672 1.0 1.0 2 Q9NWS0 1 +Granulocyte chemotaxis 0.305741387760205 0.0674184768904662 0.9462485602216816 1.0 1.0 16 P35613,O94813 2 +Negative regulation of glycolytic process 0.4765650606358458 0.0662478990090475 0.947180462609042 1.0 1.0 2 P40763 1 +Multicellular organismal homeostasis 0.2963427503433894 0.0661704355821617 0.947242134159754 1.0 1.0 66 Q9Y624,P04062,Q13501,P02786,Q16625,Q9UIQ6,P38571,Q06481,Q15555,P51790,O76024,O14773,P11166,Q16739,P23786 15 +Estrogen metabolic process 0.3706421939832435 0.065209153820836 0.948007472948134 1.0 1.0 5 O95470 1 +Positive regulation of g protein coupled receptor signaling pathway 0.3812063255872598 0.0647481576483366 0.948374518979423 1.0 1.0 4 Q15043 1 +Pigmentation 0.3006560186984856 0.0643777821556807 0.9486694205935178 1.0 1.0 17 P62820,Q04656,O75787,Q8TAA9 4 +Cell fate determination 0.4347705380558649 0.0638801435787101 0.9490656631101833 1.0 1.0 3 Q07820 1 +Regulation of protein dephosphorylation 0.3055186195409196 0.0636468387304614 0.9492514354071098 1.0 1.0 30 P04062,Q15257,P62942,P42345,Q86XL3,P04899,P0DP25 7 +T cell lineage commitment 0.3684383202099704 0.0598425330392139 0.95228104979117 1.0 1.0 5 P78527,P61586,P40763,P42345 4 +Rig i signaling pathway 0.3173936289932031 0.0585056426950196 0.953345867975082 1.0 1.0 11 Q9NUD5 1 +Cellular response to topologically incorrect protein 0.3080885139661278 0.0566871287965354 0.9547944272608112 1.0 1.0 34 P48723,O76024,Q15363,Q9BUN8,Q9Y4P3,Q96HY6 6 +Protein autophosphorylation 0.308674911052929 0.0557043048552836 0.955577370051086 1.0 1.0 35 Q15375,P17612,P42345,P00533,P0DP25,P36896 6 +Circulatory system development 0.3122311272549856 0.0554959653361493 0.9557433441939782 1.0 1.0 156 P52789,O75844,P55011,P09601,Q9NRG4,O95470,P04114,Q14126,Q08431,O14786,Q86UE4,Q9NZ08,Q13685,P01130,Q9NQC3,P19021,P10644,P06756,P98164,P16870,Q5SZK8,Q04656,P00533,O94813,P10253,Q9Y251,P35613,P42892,P43121,Q07954,Q15363 31 +T cell homeostasis 0.3514932720708855 0.0551577060492344 0.956012823293804 1.0 1.0 6 P62753,O95067,P42574,P49327,P31749 5 +Endothelial cell development 0.2900896359902385 0.0550797371828051 0.9560749390207628 1.0 1.0 20 Q9Y624,P62820,Q9Y251 3 +Negative regulation of chromatin binding 0.4268852459016369 0.0543103461460987 0.9566879066880528 1.0 1.0 3 Q7Z5K2,Q08209 2 +Negative regulation of transforming growth factor beta production 0.4605047525401429 0.0539905185237395 0.9569427183467628 1.0 1.0 2 Q9Y5K6 1 +Golgi localization 0.375204985241063 0.0538027131340113 0.9570923478842208 1.0 1.0 4 P48444,P60953,Q9Y678 3 +Maintenance of cell polarity 0.3751645936092769 0.0537309693270667 0.9571495084783463 1.0 1.0 4 O15511 1 +Response to uv b 0.4598492297607303 0.0535436219016117 0.9572987752247072 1.0 1.0 2 Q01831 1 +Positive regulation of isotype switching to igg isotypes 0.4598492297607252 0.0535436219016081 0.9572987752247102 1.0 1.0 2 Q96QE3 1 +Negative regulation of autophagosome assembly 0.4255737704917987 0.0527931014995237 0.9578967580432318 1.0 1.0 3 Q8WVM8,O75396 2 +Coenzyme a metabolic process 0.3439701293329872 0.0507037616251259 0.9595615791634956 1.0 1.0 7 Q8WVC6 1 +Paranodal junction assembly 0.453949524745972 0.0496997549595117 0.9603616517338364 1.0 1.0 2 O15228 1 +Epidermis development 0.3108150646630597 0.0494565977928361 0.9605554247894414 1.0 1.0 48 O75844,P16615,Q04656,Q9Y6M7,P00533,P51648,Q16739,P36896,Q13510,Q9Y251 10 +Steroid esterification 0.4221701551300723 0.0489530039230755 0.9609567484397864 1.0 1.0 3 Q6IAA8 1 +Necroptotic signaling pathway 0.4503441494591806 0.0475044159180774 0.9621112109173188 1.0 1.0 2 Q13546 1 +Maintenance of postsynaptic specialization structure 0.4496886266797699 0.0471174429762407 0.9624196252922604 1.0 1.0 2 Q15334 1 +Negative regulation of stress activated protein kinase signaling cascade 0.3249621541971824 0.0470170143754153 0.962499667013994 1.0 1.0 9 P78318,Q96J02 2 +Immune response 0.3450082238079612 0.0462158943717401 0.9631381741342406 1.0 1.0 210 P09601,Q08722,Q96FW1,Q9NUD5,Q96J02,P05067,Q5ZPR3,P02786,P10321,O00584,O15400,P53634,Q9NZ08,O43657,Q9NQC3,O00115,Q9UNK0,P01889,Q9NUQ9,Q06481,Q04656,P51809,P48960,Q9Y487,P04439,Q03518,O75955,Q07954,P15529,Q13137,Q5KU26,P11279,Q8TCT8 33 +Neuromuscular synaptic transmission 0.4464110127826809 0.0452375921496022 0.963917930705562 1.0 1.0 2 O60333 1 +Cellular response to external stimulus 0.3068341136368346 0.0448383939718434 0.96423612188967 1.0 1.0 55 Q9Y624,P04062,Q96QD8,P56192,P21964,P09601,Q9Y4P8,Q96C86,Q9HB90,P42345,O95831,P08069,Q02487,P11166,Q9Y4P3,P20020 16 +Regulation of dna ligation 0.4173770491803211 0.0437811096559955 0.9650788849550728 1.0 1.0 3 P18887,Q9UBB9 2 +Maintenance of centrosome location 0.4431333988855999 0.0434475064535526 0.9653448087570152 1.0 1.0 2 P43034 1 +Maintenance of organelle location 0.4431333988855999 0.0434475064535526 0.9653448087570152 1.0 1.0 2 P43034 1 +Regulation of genetic imprinting 0.4428056374958896 0.0432733335518472 0.9654836480469732 1.0 1.0 2 Q6PD62 1 +Genomic imprinting 0.4428056374958896 0.0432733335518472 0.9654836480469732 1.0 1.0 2 Q6PD62 1 +Negative regulation of protein targeting to mitochondrion 0.41662139570101 0.0429906073235173 0.9657090212028336 1.0 1.0 3 P49257 1 +Meiotic chromosome segregation 0.2929098126469698 0.042130004501558 0.9663950612653504 1.0 1.0 23 Q92791,Q9BTX1,Q9BXW9,Q9BZD4 4 +Postsynapse to nucleus signaling pathway 0.4382169780399793 0.0409249153615445 0.9673557544971212 1.0 1.0 2 P52292 1 +Regulation of postsynapse organization 0.3004865345875939 0.0408092006419951 0.967448004419028 1.0 1.0 16 Q15375,P19022 2 +Release of cytochrome c from mitochondria 0.3070620015568785 0.0396693311486626 0.9683567526201592 1.0 1.0 14 Q9H3K2,Q3ZCQ8,O60313,Q96A26 4 +Meiotic cell cycle checkpoint signaling 0.4131147540983528 0.0394097368945616 0.9685637170222908 1.0 1.0 3 Q08J23,P33981 2 +Monosaccharide catabolic process 0.3066133717999705 0.037614299044399 0.9699952070015104 1.0 1.0 14 P16278 1 +Execution phase of apoptosis 0.299452537762197 0.0356722577707807 0.9715436915597224 1.0 1.0 16 O00115 1 +Behavioral response to cocaine 0.4254342838413588 0.0352193834174665 0.9719048060865968 1.0 1.0 2 Q00535 1 +Pronephros development 0.4195345788266075 0.0329690773540079 0.9736992469263102 1.0 1.0 2 P61619 1 +Transcription coupled nucleotide excision repair 0.3627418825844489 0.0328819139060716 0.9737687556086764 1.0 1.0 4 P19447,Q93009,P18074 3 +Apoptotic process involved in heart morphogenesis 0.4185512946574847 0.0326158846070112 0.9739809024852404 1.0 1.0 2 Q12948 1 +Response to glucagon 0.4185512946574808 0.0326158846070095 0.9739809024852416 1.0 1.0 2 P08574 1 +Positive regulation of chemokine c x c motif ligand 2 production 0.4172402490986507 0.0321543712135852 0.9743489438423354 1.0 1.0 2 P14174 1 +Chemokine c x c motif ligand 2 production 0.4172402490986507 0.0321543712135852 0.9743489438423354 1.0 1.0 2 P14174 1 +Positive regulation of dna ligation 0.4172402490986489 0.0321543712135847 0.9743489438423358 1.0 1.0 2 P18887 1 +Regulation of hippo signaling 0.4156014421501083 0.0315923696744004 0.9747971284718592 1.0 1.0 2 Q01085 1 +Negative regulation of circadian rhythm 0.4146181579809779 0.0312629861290066 0.9750598087595664 1.0 1.0 2 P23246 1 +Male meiosis i 0.4129793510324341 0.0307268194746232 0.9754874024094712 1.0 1.0 2 P54652 1 +Cellular response to xenobiotic stimulus 0.2952899654957368 0.0297006400629288 0.9763058014517724 1.0 1.0 26 P16435,P27544,O43169,P02786 4 +Establishment of mitochondrion localization 0.3102487002917653 0.0290921353402447 0.9767911082340384 1.0 1.0 11 Q92692,O60313 2 +Negative regulation of mrna splicing via spliceosome 0.3042354647693797 0.0268182187827432 0.9786047219565296 1.0 1.0 14 P26368,Q07021 2 +Negative regulation of lipid biosynthetic process 0.341213670430889 0.025645042363449 0.9795404592598602 1.0 1.0 6 P05023 1 +Neuronal action potential 0.3533254417394913 0.0254131558832116 0.9797254176201556 1.0 1.0 5 P04062 1 +Cell cell junction assembly 0.2984008744256948 0.0251496247121211 0.979935617886903 1.0 1.0 29 Q9Y624,P19022,P17612,Q16625,Q9BTW9,Q8WUM4,P36404,Q16513,O43815 9 +Embryonic hindlimb morphogenesis 0.3900360537528622 0.0247302466778722 0.9802701290938896 1.0 1.0 2 P35222 1 +Hindlimb morphogenesis 0.3900360537528622 0.0247302466778722 0.9802701290938896 1.0 1.0 2 P35222 1 +Development of secondary female sexual characteristics 0.3900360537528607 0.0247302466778719 0.9802701290938898 1.0 1.0 2 Q99623 1 +Branching involved in mammary gland duct morphogenesis 0.3900360537528607 0.0247302466778719 0.9802701290938898 1.0 1.0 2 Q99623 1 +Endoplasmic reticulum plasma membrane tethering 0.3967213114754067 0.0245156680489863 0.9804412861753464 1.0 1.0 3 O95292,A0FGR8 2 +Endoplasmic reticulum localization 0.3967213114754067 0.0245156680489863 0.9804412861753464 1.0 1.0 3 O95292,A0FGR8 2 +Positive regulation of collagen metabolic process 0.3828253031792759 0.0233489341410251 0.9813719385382232 1.0 1.0 2 P08670 1 +Dna catabolic process exonucleolytic 0.380530973451322 0.0229522539846621 0.9816883587044308 1.0 1.0 2 Q9GZR2 1 +Corpus callosum development 0.3947540983606544 0.0229248671612989 0.9817102044798268 1.0 1.0 3 Q00535,P43034 2 +Constitutive secretory pathway 0.3723369387086138 0.0216890586364254 0.98269599166456 1.0 1.0 2 Q8TBQ9 1 +Histone h4 r3 methylation 0.3703703703703647 0.0214191917944283 0.9829112642391004 1.0 1.0 2 O14744 1 +Apoptotic process involved in morphogenesis 0.3513779527559031 0.0212805746632416 0.9830218395039054 1.0 1.0 5 Q14160,Q12948,P30154,P20248 4 +Mammary gland duct morphogenesis 0.3901639344262279 0.0193692955043531 0.984546504449802 1.0 1.0 3 Q14160,Q99623 2 +Regulation of response to interferon gamma 0.3901639344262233 0.0193692955043497 0.9845465044498044 1.0 1.0 3 Q16543,P08238 2 +Regulation of apoptotic process involved in development 0.3510324483775739 0.0193438838353598 0.9845667762301088 1.0 1.0 2 Q12948 1 +Regulation of pigmentation 0.3510324483775746 0.0193438838353598 0.9845667762301088 1.0 1.0 2 Q96AX1 1 +Female meiosis i 0.3898360655737679 0.0191235731718008 0.9847425261956336 1.0 1.0 3 Q15645,O95067 2 +Meiotic chromosome condensation 0.3532305673991456 0.0185433551728975 0.985205391076146 1.0 1.0 4 Q15021,O95347,Q15003 3 +Peptidyl proline modification 0.2995440102184828 0.0183034042034775 0.9853968117606876 1.0 1.0 31 O95302,Q9BV86,Q9Y680,P13674,Q9NWM8,P07237 6 +Uronic acid metabolic process 0.333988856112743 0.0181993136692253 0.9854798501591562 1.0 1.0 2 Q9NUJ1 1 +Negative regulation of sister chromatid cohesion 0.3885245901639308 0.0181515255214315 0.9855179732870374 1.0 1.0 3 Q7Z5K2,Q14674 2 +Response to ketone 0.305031735843417 0.0178071835013596 0.9857926740640428 1.0 1.0 38 P04062,Q96C86,P16278,O95831,P08069,O94813,Q969T9,P16435,P0DP25,P07196,Q9H7B4,P20020 12 +Threonine metabolic process 0.3254670599803266 0.017801751036917 0.98579700785659 1.0 1.0 2 O43175 1 +Meiotic spindle organization 0.3490813648293909 0.016496997134763 0.9868378977023008 1.0 1.0 5 P30153,Q14674,O95067,O14965 4 +Regulation of calcium ion transport 0.2956949489598532 0.0159552218602777 0.9872701149216992 1.0 1.0 28 P17612,P62942,O76024,P0DP25,P21796,P20020 6 +Sulfur compound biosynthetic process 0.3035020400915629 0.0157700503814885 0.9874178417985892 1.0 1.0 36 P09622,Q8TB61,P50897,Q9UMR5 4 +Fungiform papilla development 0.382950819672128 0.0142105879458263 0.9886619728811076 1.0 1.0 3 P35222,Q13547 2 +Fungiform papilla morphogenesis 0.382950819672128 0.0142105879458263 0.9886619728811076 1.0 1.0 3 P35222,Q13547 2 +Tongue morphogenesis 0.382950819672128 0.0142105879458263 0.9886619728811076 1.0 1.0 3 P35222,Q13547 2 +Tongue development 0.382950819672128 0.0142105879458263 0.9886619728811076 1.0 1.0 3 P35222,Q13547 2 +Hair follicle placode formation 0.382950819672128 0.0142105879458263 0.9886619728811076 1.0 1.0 3 P35222,Q13547 2 +Regulation of anion channel activity 0.3822950819672006 0.013766833175546 0.9890160033174478 1.0 1.0 3 P08183,Q9HD26 2 +Negative regulation of protein serine threonine kinase activity 0.2843394084977458 0.0119091647067689 0.9904980859555088 1.0 1.0 21 P10644,Q92673 2 +Pattern specification process 0.3013347767157648 0.0115491437052173 0.990785321394052 1.0 1.0 34 O75569,P98164,O75787,Q9Y2W6,O75386,Q15363,O14786 7 +Outflow tract morphogenesis 0.3147836512511091 0.0105578978736811 0.9915761727919044 1.0 1.0 9 P98164 1 +Response to transforming growth factor beta 0.299300562380532 0.0102430198601346 0.9918273955087208 1.0 1.0 32 Q06481,Q92896 2 +Establishment of golgi localization 0.3750819672131075 0.009152530028489 0.9926974395525878 1.0 1.0 3 Q9Y678,P60953 2 +Single fertilization 0.2902669696977174 0.0082827268128013 0.9933914157168762 1.0 1.0 25 P15529,P07686,P45880 3 +Erythrocyte homeostasis 0.3023219906400353 0.0078385272153369 0.9937458242008904 1.0 1.0 36 P36896,O00115 2 +Negative regulation of autophagy of mitochondrion 0.3681967213114702 0.0051867073740238 0.9958616248199212 1.0 1.0 3 P49815,Q9NQ88 2 +Negative regulation of mitophagy 0.3681967213114702 0.0051867073740238 0.9958616248199212 1.0 1.0 3 P49815,Q9NQ88 2 +Cell cell signaling 0.317429903778805 0.0032376936533351 0.9974166987347068 1.0 1.0 170 P20339,Q13501,P55011,Q9UIQ6,P05556,Q12834,Q5SQN1,P62820,Q13277,O14786,P05067,P19022,P17612,Q96K76,O00560,Q8TAA9,P50897,P0DP25,Q13641,Q9P0T7,Q9UQB8,O75787,P16870,Q15042,Q9P1Z2,Q99538,P16615,Q92542,P00533,Q7L0J3,P04899,P49815,Q16531,Q9BZK7,P50402,P51809,P48960,O75955,P51790,Q07954,Q13308,Q96A49,P57105,P43490 44 +Skin development 0.3038788234971415 0.0030796013079091 0.9975428375469236 1.0 1.0 40 P04062,O75844,Q04656,Q16739,P36896,Q13510,Q9Y251 7 +Negative regulation of transport 0.2756585379943808 0.0011816175927773 0.9990572057853412 1.0 1.0 74 P06756,P09601,Q06481,Q04656,Q08722,O00560,P31751,P21796,P05067,Q96PU5 10 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..182de8d30b04476eee5c95ae094e8592a3411c36 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in coronary vascular morphogenesis", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular valve development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Bronchus development", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell differentiation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to progesterone stimulus", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondroblast differentiation", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Commissural neuron axon guidance", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion import", "Copper ion transmembrane transport", "Copper ion transport", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial nerve morphogenesis", "Cranial nerve structural organization", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna cytosine deamination", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Elastic fiber assembly", "Elastin metabolic process", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardium development", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facial nerve morphogenesis", "Facial nerve structural organization", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat pad development", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated inhibitory signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus cell migration", "Hypothalamus development", "Hypothalamus gonadotrophin releasing hormone neuron differentiation", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immune effector process", "Immune response", "Immune response inhibiting cell surface receptor signaling pathway", "Immune response inhibiting signal transduction", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological memory formation process", "Immunological memory process", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 17 production", "Interleukin 18 mediated signaling pathway", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lacrimal gland development", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein particle remodeling", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteolysis", "Lymph vessel development", "Lymph vessel morphogenesis", "Lymphangiogenesis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Mast cell proliferation", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane fusion involved in viral entry into host cell", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Motor neuron migration", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immune response to tumor cell", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic process involved in development", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of atpase coupled calcium transmembrane transporter activity", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axon extension involved in axon guidance", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cardiocyte differentiation", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of complement activation", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of g0 to g1 transition", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of histone acetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of humoral immune response", "Negative regulation of humoral immune response mediated by circulating immunoglobulin", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 beta production", "Negative regulation of interleukin 1 mediated signaling pathway", "Negative regulation of interleukin 1 production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein metabolic process", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage derived foam cell differentiation", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotaxis", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of pathway restricted smad protein phosphorylation", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of smad protein signal transduction", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor 2 signaling pathway", "Negative regulation of toll like receptor 4 signaling pathway", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of triglyceride catabolic process", "Negative regulation of triglyceride metabolic process", "Negative regulation of trophoblast cell migration", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest cell migration involved in autonomic nervous system development", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Nodal signaling pathway", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Noradrenergic neuron development", "Noradrenergic neuron differentiation", "Norepinephrine metabolic process", "Nose development", "Notch receptor processing", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Otic vesicle development", "Otic vesicle formation", "Otic vesicle morphogenesis", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parasympathetic nervous system development", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification process", "Penetration of zona pellucida", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagosome maturation", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axon extension involved in axon guidance", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cd8 positive alpha beta t cell differentiation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion mediated by integrin", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cell adhesion mediated by integrin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of enamel mineralization", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage derived foam cell differentiation", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of memory t cell differentiation", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immune response to tumor cell", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide mediated signal transduction", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of peroxisome proliferator activated receptor signaling pathway", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phospholipid translocation", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of regulatory t cell differentiation", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tooth mineralization", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein palmitoylation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside catabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cd8 positive alpha beta t cell differentiation", "Regulation of cdc42 protein signal transduction", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement activation classical pathway", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of defense response", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of enamel mineralization", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of humoral immune response mediated by circulating immunoglobulin", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphangiogenesis", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage derived foam cell differentiation", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immune response to tumor cell", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pattern recognition receptor signaling pathway", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sensory perception", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell division", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of ventricular cardiac muscle cell membrane depolarization", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoprotein", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 18", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lithium ion", "Response to luteinizing hormone", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to staurosporine", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cell programmed cell death", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of extracellular ligand from receptor", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal complex assembly", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Smoothened signaling pathway involved in ventral spinal cord patterning", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spinal cord patterning", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Tolerance induction to self antigen", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Trigeminal ganglion development", "Trigeminal nerve development", "Trigeminal nerve morphogenesis", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent glycoprotein erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urea cycle", "Urea metabolic process", "Ureter development", "Ureter morphogenesis", "Ureteric bud elongation", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Vestibulocochlear nerve development", "Vestibulocochlear nerve morphogenesis", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APLP2", "APOB", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC2", "ASCC3", "ASF1B", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRD8", "BRIX1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C17orf75", "C19orf70", "C1QBP", "C20orf27", "C2CD5", "CAB39", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASP2", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX4", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC25", "CCDC47", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2AP", "CD2BP2", "CD302", "CD320", "CD3EAP", "CD46", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CDYL", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPI", "CENPV", "CEP290", "CEP44", "CEP55", "CERK", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLIP1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT4", "CNOT9", "CNP", "CNPY2", "COA3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPE", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT2", "CPVL", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D4", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPH2", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM83D", "FAM91A1", "FAM98A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FREM2", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLM1", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INTS10", "INTS12", "INTS13", "INTS14", "INTS2", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRS4", "ISCU", "IST1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIRREL1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMB1", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8E", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYSMD3", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAP4K5", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED12", "MED16", "MED17", "MED24", "MED4", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL7A", "MFGE8", "MFN1", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL28", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS15", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MVB12A", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NBR1", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NENF", "NES", "NEU1", "NF1", "NFATC2IP", "NFS1", "NHP2", "NID1", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PAM", "PANK4", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHPT1", "PI4K2A", "PI4KB", "PICALM", "PIGA", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIN4", "PINX1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNN", "PNP", "PNPT1", "PODXL", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL5", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF219", "RNF220", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAGC", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCB", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERINC1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMPDL3A", "SMS", "SMU1", "SMYD2", "SMYD3", "SMYD5", "SNAP23", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TAX1BP1", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLCD1", "TLK2", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM199", "TMEM201", "TMEM206", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM43", "TMEM59", "TMEM87A", "TMEM9", "TMEM97", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TROVE2", "TRRAP", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN6", "TSR1", "TSR2", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TULP3", "TWF1", "TWISTNB", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", 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2.9859829576381497e-06 +Intrinsic component of endoplasmic reticulum membrane 26 48 3.202884448022022 0.0013605856172058 21.439320388349515 53.03155339805825 1.5445183869163015 0.2945609219212759 9.936629672422429 6.151523176643304 2.1054078800196185 0.3580268322643601 2.92512810570086e-08 0.4570575797650001 0.1209939299005533 0.000235412956108 1.301346043430078e-09 +Endoplasmic reticulum golgi intermediate compartment membrane 19 25 3.201707078813921 0.00136615841847 10.49271844660194 25.839805825242717 1.5441023898993702 0.2324243418613106 5.505729177420246 3.7718384126099376 1.49831312620529 0.2965572765953523 1.4997273427381434e-06 0.0285808600856777 0.0978881295505725 4.818233124362865e-05 1.5821786335632432e-06 +Golgi associated vesicle 13 35 3.166475027002164 0.0015429859415849 6.745145631067961 30.33009708737864 0.696501539533066 0.3869218626415568 3.3093865809086713 3.3403631844705557 1.2881306559419168 0.3350067162782171 4.2805215713128e-07 1.726903454015469e-05 4.573392792239334e-05 3.5183752430174114e-05 3.6886684783408488e-06 +Azurophil granule membrane 12 22 3.149787940092445 0.0016338901219155 7.856796116504855 21.259708737864077 1.0757479237162697 0.2373572682944545 3.393508570011604 2.63895903142419 1.639408148995933 0.2881313440808664 1.96915913986456e-08 0.1991580424676108 0.0009611330378982 1.2462086263855016e-05 1.6583857576792126e-07 +Recycling endosome 20 35 3.139638461794798 0.0016915645464712 11.66504854368932 38.48300970873787 0.3314123370484901 0.5655153978404952 4.733627044629046 5.712973030267684 1.060328776827888 0.3489425897551162 7.633764685619644e-05 0.1536755608549872 0.1631943729313839 0.0002043047119152 0.0002228521240553 +Transport vesicle membrane 26 45 3.112929719554743 0.0018524012381344 12.62135922330097 42.37378640776699 0.5402420874587609 0.5343084089707166 5.404271063272784 4.511161156897919 1.052801184280702 0.3556606283757049 2.153502623539549e-07 0.4649456287210195 0.007977720576706 0.0002892307138279 2.2102003843970397e-07 +Endosome 83 218 3.079615146595827 0.0020726823261629 49.68446601941748 210.85679611650485 0.3589512364806963 0.6263779709054735 15.417095902733692 27.960293924368397 1.2603534839168704 0.3964197633252465 5.6930679458260354e-18 0.0013292234300135 0.0002590973706164 1.063485711716893e-12 8.788775776425895e-16 +Exocytic vesicle 21 38 3.0721105388579284 0.0021255099833641 12.106796116504857 38.40533980582524 0.7408080162244459 0.4227017753873355 4.952517495270036 4.6543925000719675 1.3317240485888555 0.365166844745196 0.0001185458090394 0.1387460234363573 0.041853968264628 2.4786764349824583e-05 0.0003044586703262 +Clathrin coated endocytic vesicle membrane 9 18 3.035760431955564 0.0023992991766845 3.796116504854369 13.682038834951456 0.0573666642471241 0.400612365903674 2.3816010903207343 1.646817383208435 1.3652035545006669 0.3297171871883064 7.883013850517869e-07 0.0121686135974036 0.0443091130960601 1.693641470299462e-05 4.065628476628564e-06 +Intrinsic component of mitochondrial membrane 22 41 3.028340998060357 0.0024590044119603 20.225728155339805 46.883495145631066 1.6360090381123027 0.2606204408334349 9.735582728924424 5.567853242112672 2.0682718238883013 0.3438986948818692 1.5102493358374857e-05 0.0005428611587646 0.0009512079801521 0.000626517772181 1.7132007441787937e-07 +Golgi cisterna 13 25 3.027565884370666 0.0024653196632387 8.524271844660195 22.490291262135923 0.9086972174309816 0.318868202549777 4.2525712614684625 5.269200019661922 1.391079392561209 0.3149122340418913 1.0671140254006452e-06 0.297366720714231 0.0052630916622981 6.238783903159406e-05 8.850050427314066e-06 +Endoplasmic reticulum lumen 25 62 3.010889192584627 0.0026048389079786 18.07766990291262 59.737864077669904 0.9896277047863468 0.3946249358858228 7.513340007333169 6.273245958458151 1.4320597420402308 0.3846324865730224 1.570162647884523e-05 0.0473127294122767 0.0002139788138078 0.0008241549035924 1.507120619652375e-07 +Presynapse 34 89 3.0045546831410466 0.0026596994368748 22.813106796116504 90.997572815534 0.4365135448276876 0.6534842370695999 7.919284748658944 8.50627945845188 0.826940228235506 0.3445781590237917 0.0054689477033407 0.3963415280031773 0.2891134304910702 0.0037098572651095 0.0027507481052712 +Inner mitochondrial membrane protein complex 30 73 2.989914589518752 0.0027905546398894 27.97087378640777 75.4635922330097 1.520604987560478 0.2664687480104057 12.043574857699111 6.447783897817093 2.3558486082891616 0.3692317407906862 5.808566043247967e-06 0.0036241696225553 0.0002703653485467 0.000353075219544 2.457177671187907e-11 +Snare complex 8 15 2.942336853945686 0.0032574537650398 6.20873786407767 15.79368932038835 0.8138466711937282 0.3737991711938105 3.1112263618988054 3.010283181947674 1.1802712183474584 0.3261149602927671 4.450799146958895e-05 0.187449079081247 0.3404254693467198 6.880235330436636e-05 0.0001790277584403 +Clathrin coated endocytic vesicle 9 23 2.941714110813911 0.0032640111109012 4.774271844660194 18.74271844660194 -0.0983362729934113 0.4816370533307881 3.136849294900222 2.1033538609603957 1.2416005860349415 0.3436375292109884 9.523282940683004e-06 0.0196403757049561 0.0693457394610891 9.297701577536192e-05 4.558635539447923e-05 +Apical plasma membrane 23 47 2.9320994772462825 0.0033667888523176 13.313106796116504 44.91504854368932 0.8056122914935105 0.4638533528605782 6.08368206230376 5.803837594461636 1.1490032654706197 0.3657186109722784 5.660699907577763e-06 0.1757629685498992 0.194273291085049 0.0015810476080818 5.787687850410522e-07 +Intrinsic component of mitochondrial inner membrane 16 29 2.9263193860859724 0.0034299860516271 13.946601941747574 31.446601941747577 1.7062420859184484 0.2149692261988765 6.992163651608136 3.3601842163433866 1.8185871159494191 0.3070405082296492 4.987837786007759e-07 9.216009865795702e-05 0.0001113664394611 0.0001846255682835 6.28778052108814e-08 +Endoplasmic reticulum golgi intermediate compartment 26 48 2.8813978482174063 0.0039591554662925 14.888349514563108 49.49271844660194 1.4759277407874345 0.3201471070907981 6.47003250199477 5.053350843348441 1.420924643396655 0.3585240832471577 1.7609537397086275e-06 0.0115248505448644 0.0681614338573012 0.0005983999159821 1.8762718809256141e-07 +Synaptic vesicle membrane 11 15 2.792682817797455 0.0052272920065807 5.099514563106796 14.07766990291262 0.7734258277348643 0.4227625879426745 2.579286376297321 2.2325453295101236 1.0485572818049853 0.3297289695807819 0.0112551624208181 0.2552681350600493 0.1163398228410075 0.0600215848699845 0.008913025090531 +Golgi cisterna membrane 9 17 2.7741586542619765 0.0055344680195363 6.233009708737864 17.101941747572816 0.7930989258143627 0.3092897028410761 3.2184356191878685 3.952300069740005 1.3504727992091758 0.2953094162507478 3.663734989749192e-05 0.2220822570468345 0.0890100643743446 0.0082403851981354 0.0001665225081846 +Multivesicular body 6 16 2.7596272958332846 0.0057867337659096 3.7742718446601944 12.094660194174756 0.0270444117783637 0.5442226252774409 2.4800207883335372 2.61498122866677 0.9464580912617488 0.3033802150556732 0.0011582598375614 1.0 0.0588586045542952 0.016869226769582 0.0032541181407787 +Endosome lumen 5 7 2.746617744393607 0.0060213268213233 1.604368932038835 3.8932038834951457 0.8845546079995737 0.2641736972645504 1.2526788149416888 1.4642180149570363 1.3478975321629194 0.2569719391794136 0.0001017286916656 0.0040679264544396 0.0155240337321844 5.543951850167897e-06 0.0002747300414667 +Phagocytic vesicle 22 39 2.723783851304121 0.0064538729560028 11.54126213592233 41.59708737864078 0.3919256884663005 0.5681630099638236 4.854259100699266 4.0100348958770144 0.9938295058309184 0.3509625084864278 4.701393760823703e-05 1.0 0.6211264656767345 0.0001483335777357 8.861976501870863e-05 +Vesicle membrane 103 265 2.7224697123729973 0.0064795972618794 59.03398058252427 252.66747572815535 0.5350285241159404 0.6113983912197217 17.512237349079548 29.567983380691818 1.3292572988488431 0.402876017449685 5.588896424026618e-24 0.0031057834639576 2.721379678963953e-06 3.02841432143008e-17 6.363433126616618e-23 +Clathrin coated vesicle membrane 9 29 2.717859151456284 0.0065705801866924 5.987864077669903 23.8373786407767 -0.1745074444216576 0.5217181929114124 3.796056755917445 2.6366094957976225 1.1352900407304896 0.3325344982200064 0.0001508043365829 0.0345877004093447 0.1163398228410075 0.000643303268372 0.000641595952047 +Golgi associated vesicle membrane 7 22 2.715228178725984 0.0066230120592531 4.201456310679611 19.589805825242717 0.79417597045559 0.3511132904952779 2.457541951272857 2.384047500904294 1.2111660039755976 0.3110721945776767 0.0001662947885833 0.0009094910101507 0.0065760397653667 0.0155108289838298 0.0005666628036471 +Azurophil granule lumen 15 46 2.6934412430650685 0.00707186090331 12.118932038834952 41.25728155339806 -0.033426136567579 0.3776020138210581 4.31782609196223 3.0753988435553 1.7699755963815147 0.3570217435028845 2.50707218043467e-09 0.0002276914442852 2.17584853501014e-06 1.6472742946342745e-11 3.3011814298220175e-08 +Copii coated er to golgi transport vesicle 11 31 2.676981497923902 0.0074288737225109 10.810679611650484 32.4247572815534 0.9209697551014924 0.3949407296339237 5.01338814607213 3.9617918728777735 1.2509556054930144 0.3456813773327062 1.3193339809715342e-05 0.0410390344011431 0.1355867800667393 0.0055274737909119 7.825314737739928e-05 +Specific granule membrane 7 14 2.6751422879890367 0.0074697539807739 4.703883495145631 15.434466019417476 0.8701513897757543 0.3699585460258285 2.477017558764293 2.6655071934549124 0.9998631482292508 0.308737972868479 0.0007090128938225 1.0 1.0 0.006410021202963 0.0022658484440293 +Cis golgi network 8 13 2.671263453195295 0.0075566311943155 5.446601941747573 14.91747572815534 1.304763677188147 0.2415633778835601 2.9087352716231463 3.2280604409731746 1.23405443481851 0.2890539664507128 0.0197211042902028 0.01497108596825 0.0538434207197609 0.0142235096743441 0.0105883475769395 +Golgi stack 17 33 2.631811956644486 0.0084930856024214 9.67233009708738 31.25242718446602 0.7055900861920908 0.4265468940333196 4.557817503574521 5.847941213698429 1.2226912303929196 0.3463938041520717 3.737229490195611e-05 0.377722993581858 0.0145704521374391 0.0005983999159821 6.98878723699714e-05 +Trans golgi network 20 63 2.6304220606126205 0.008527892131753 15.419902912621358 63.34466019417476 0.3899535194812628 0.596168565313415 5.947659406670704 9.796108085479462 0.9254595120691144 0.3511819564605877 0.0003968356182633 0.068526741281428 0.0410933730804736 0.0030335725815751 0.000576187275183 +Outer mitochondrial membrane protein complex 10 16 2.6279921993703264 0.0085890485287676 7.157766990291262 15.730582524271844 1.3245491566248977 0.2112996285983387 3.5767402396348245 0.8689557679680192 1.477430451036954 0.2853006280851536 0.0009961844667822 0.0001122733832082 0.0008717411361388 0.01180448121602 2.1902966903943494e-06 +Clathrin coated vesicle 13 52 2.6065810827075344 0.0091451168936564 9.936893203883496 47.157766990291265 0.2628715125167937 0.534532305855711 4.553447222704333 4.879804116719352 1.1779559306555245 0.358217133589648 0.000404817549901 0.1162566833370341 0.1126980972536071 0.0007423140273619 0.0023204633922893 +Nuclear outer membrane endoplasmic reticulum membrane network 134 290 2.6030726838301077 0.0092392363813358 98.3519417475728 305.0218446601942 1.8626549185660248 0.4346737740195964 40.114822105305365 33.029069404441934 2.648813561163414 0.4525721946789457 2.338434950921255e-23 0.0089582662882427 0.0007819326934647 1.1904550277117685e-08 2.6631915973360843e-25 +Trans golgi network transport vesicle 4 15 2.586843897323755 0.0096859461926579 4.007281553398058 12.91019417475728 -0.165056273529708 0.5953281491980702 2.4210736181324606 1.5961704659812874 0.9219447964283688 0.3231276900084591 0.004837457692714 0.1263420182810564 0.0293903981750984 0.0043549454623746 0.010278445998416 +Golgi apparatus 138 318 2.5494480708623626 0.0107893578035673 79.29126213592232 307.80825242718447 1.0941692666231844 0.5225509759640199 24.90716006851961 39.34912971804267 1.7376904428153446 0.4394682295132952 1.6126506870535938e-17 4.3870532118964073e-07 5.106165356184952e-10 1.1687218276631704e-16 8.706187517251843e-17 +Intrinsic component of synaptic vesicle membrane 8 10 2.5423451060065334 0.0110111393810283 3.648058252427184 9.116504854368932 0.724313202500786 0.4129003553732678 2.1933086936710184 1.7154408466980504 1.018214829869002 0.3297596143558817 0.0041077133853001 0.1221118561195742 0.0274603336438859 0.0038040834633598 0.0015706126808535 +Nuclear envelope lumen 2 6 2.540377613047107 0.0110732841191236 1.5922330097087378 4.730582524271845 0.2740214243637495 0.4274662744917171 1.0138544466097483 0.5098416377826835 1.1584731829510644 0.3162624936844113 0.0012042824030618 0.028497516818446 0.0013376518177504 0.0002661275452166 0.0020376306093415 +Lumenal side of membrane 6 10 2.530453400448448 0.0113915215668103 3.686893203883495 9.509708737864075 0.6270696996832885 0.3351332813726532 1.8490414883089543 0.9791034697552432 1.2332692274886168 0.3003490996154719 0.000182778198458 1.0 1.0 0.0017432511761074 5.493155547881244e-05 +Presynaptic active zone 7 15 2.5178410895788192 0.0118076580368149 4.803398058252427 14.970873786407768 0.3940654670567658 0.5114928405011878 2.7795522630987173 1.9568466345271975 0.9528581059832693 0.3105803383532612 0.135866136448837 0.2107016729382093 0.0803922289273931 0.1151104414767163 0.0022658484440293 +Neuromuscular junction 8 17 2.51398608179525 0.0119375144943234 4.62621359223301 16.633495145631066 0.4855035135155566 0.54061233402628 2.386469186408936 2.9236472131013795 0.8090611388618595 0.3124321260069755 0.0289328707312566 0.0180235679120217 0.0080456420559546 0.0198035379531722 0.0558327828623465 +Trans golgi network membrane 14 26 2.508335271230718 0.0121301511905067 7.097087378640777 25.808252427184467 0.4300178223009387 0.4839581535123586 3.4857952056404495 4.861642003007495 1.0577526504941306 0.3235584371830635 0.0004795230822878 0.0444222413024675 0.1454623761357323 0.0002733113837236 0.0001215966677287 +Organelle membrane contact site 11 15 2.5012939860321466 0.012374041206572 6.817961165048544 16.400485436893202 0.815819301321945 0.3904411977369264 3.451940177462974 2.047328298639296 1.2919706717077657 0.3464717655445403 0.0516532455250465 1.0 0.2872333566147377 0.2076979954646016 0.0257423149537502 +Organelle subcompartment 177 357 2.48638566528343 0.0129048029454741 115.97815533980582 370.4077669902912 1.8466078375892352 0.461199583276842 45.24176702976874 43.040100266333 2.697642340677977 0.4541841641473397 1.2517633602396815e-27 0.0005104284725754 3.664194850294712e-05 5.389200027611487e-12 1.1773865327873497e-29 +Clathrin coated pit 7 27 2.4782393180144786 0.0132032552646439 6.813106796116505 23.92233009708738 -0.3634603746412232 0.5290548253531329 3.4198908541960824 3.6938398480544263 1.0001526474813611 0.326415656204558 0.0019593441096619 0.0025436512836883 0.0021465314893355 0.000423196822916 0.005918859062877 +Intrinsic component of golgi membrane 7 9 2.469851581090409 0.0135169120173401 4.655339805825243 10.08495145631068 1.3178763872097854 0.2129685736028588 2.6046347098798024 1.9780511021437377 1.2704958978874823 0.2699640456705705 0.0064867153896704 0.1835089509173778 0.0614247268920475 0.0182997950486615 0.0037452233271246 +Golgi lumen 3 5 2.422299795437222 0.0154226212746992 1.745679012345679 4.548148148148148 1.1368717941323 0.2457507117503182 1.2159484823715767 1.4039724163790972 1.161880305109492 0.2643265801751675 0.0389596508032961 0.1430638950507344 0.266209970857853 0.0070923684446229 0.0674365169251515 +Membrane microdomain 28 67 2.385284488326457 0.0170659182867525 14.75485436893204 63.49029126213592 0.5762129399877682 0.5023556315347317 6.545256989336744 6.436953608643344 1.167657055169838 0.3823949317010994 1.1817835347037028e-05 0.6107582205032194 0.5597140736485569 0.0002611032613839 7.307469487811582e-06 +Specific granule 13 35 2.3715247747092616 0.0177148590158313 8.742718446601941 34.25242718446602 0.2855678993885875 0.5987101990719559 3.996578681039245 4.349352025395783 0.8117156191720855 0.3097397590453908 5.569352233518209e-05 1.0 1.0 5.499583675645157e-05 8.94857496989466e-05 +Protein lipid complex 4 6 2.3351912489235613 0.0195334320946165 0.9733009708737864 4.152912621359223 0.8806614337674874 0.2932450111231078 0.8822773800999041 1.1227636940840768 1.0732388951245535 0.2459144485958364 0.0003209345081955 0.0742352733278267 0.1432798584585485 0.0004862334359502 0.0007388687073799 +Autophagosome 9 27 2.323740726112037 0.0201393942921643 7.490291262135922 28.23058252427185 0.2382857558920592 0.551676712271876 3.4770262532301657 5.388565442188036 0.9533210099421008 0.3228297396792804 0.0344992377291448 0.3624074851394556 0.2248900268904883 0.0750173773780456 0.0817388517598971 +Lumenal side of endoplasmic reticulum membrane 5 8 2.31825749810287 0.0204353308096139 3.0776699029126213 7.361650485436893 0.5475818769285827 0.3637002691484017 1.5990854205757892 0.8689828861838115 1.1522443815379428 0.2937666584254462 0.0005886601589281 1.0 1.0 0.0087554356838108 0.0001429815632908 +Er to golgi transport vesicle membrane 7 21 2.2983537185112124 0.0215416653581546 6.495145631067961 21.890776699029125 0.3958870084748403 0.5141628679854253 3.1618901389258056 2.1225127942575894 0.9657155478739712 0.3164691847513972 0.0003325595650647 1.0 1.0 0.0901467992310857 0.00110124435718 +Plasma membrane raft 8 20 2.227478191435436 0.0259153317564764 3.7766990291262137 20.32281553398058 0.7112808016258366 0.472560537547523 2.42331730763724 2.337985988096463 0.7987766314420426 0.3131348956705554 0.1344768283620574 1.0 1.0 0.2210522410556178 0.0430335103135439 +Tim23 mitochondrial import inner membrane translocase complex 3 6 2.214705542183876 0.0267802822128617 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 0.0006977887477165 0.0012105019492812 0.0047533286028597 9.701143498590324e-05 9.569573614901708e-05 +Blood microparticle 5 16 2.169945383252802 0.030010983723556 4.735436893203883 17.08252427184466 0.278306270999014 0.48728609275096 2.8336409309630577 1.4740425350178823 1.0421411126986748 0.31816279579515 0.0064867153896704 0.1835089509173778 0.3339976348230559 0.0032788281256578 0.0150707717640174 +Endoplasmic reticulum 201 470 2.1440998301067022 0.0320248886894005 139.71116504854368 475.50728155339806 1.972579372344309 0.4597126503683645 50.29410175615224 47.94654634280014 2.8130551221954065 0.458598772128197 4.3865262256677e-32 0.0012829219468262 1.884067644639376e-05 1.246386055117701e-13 1.837698054016852e-36 +Microbody membrane 13 25 2.132352520839161 0.0329778774331206 9.83980582524272 26.8373786407767 1.0322166739723002 0.3740701224912098 5.101262737371427 4.075770333088885 1.3138416014090577 0.3534887732287703 0.1990528229728135 1.0 0.4242240140575919 0.4035011436345253 0.2992569105103682 +Integral component of synaptic vesicle membrane 5 6 2.1302046647184887 0.0331547201228328 2.2475728155339807 4.910194174757281 0.8567274645780141 0.3149754325120096 1.3818760752746044 1.4445051429216968 1.1133243513780926 0.2989777184888048 0.0041482574964162 0.0786913117950012 0.0113213926532688 0.0074273483269255 0.0010053263520343 +Pore complex 5 9 2.1300632707733427 0.0331663901435532 3.2111650485436893 8.830097087378642 1.029129610796519 0.2182996080526768 1.893158762220583 0.772882004264421 1.343874754683687 0.2717215815078918 0.0004396452857286 1.0 1.0 0.0074273483269255 0.0010053263520343 +Receptor complex 11 30 2.1257165254393144 0.0335268701016595 4.546116504854369 19.37135922330097 -1.0257716368983243 0.3014359024485322 2.884560417457156 4.82966712727482 1.2452382063769163 0.3057220790362489 0.0023680945653168 0.0006456008807191 0.0027791372809613 0.0002179029982872 0.0048055107883881 +Respirasome 19 43 2.1003259358750506 0.0357001792725946 15.08495145631068 43.37378640776699 1.2524823540042158 0.2922262294299136 6.290312072426717 4.489587979561489 1.7783434517583476 0.3462844006183536 7.034299690096876e-06 0.3371313972628795 0.0089732445190698 0.0010205325993841 1.6606015152181676e-08 +Copi coated vesicle membrane 4 13 2.046487925421765 0.0407083892437867 2.9611650485436893 12.451456310679612 0.9351146201256926 0.2894293018559171 1.7580457491925867 1.2208038158644114 1.2401568068418547 0.2855671555488221 0.0003209345081955 0.0026008925831016 0.0100519320580488 0.0561137872346343 0.0007388687073799 +Calcium channel complex 5 8 2.035569700633689 0.0417935828996938 2.4150485436893203 7.298543689320389 0.1538765288718164 0.4525613292140901 1.4615016707365889 1.3130036030733032 1.08449347730351 0.3081575616966512 0.6140637333650861 1.0 1.0 1.0 0.0981468657129251 +Chloride channel complex 3 6 2.0283561142883606 0.0425239157005581 1.6310679611650485 5.075242718446602 0.2943428743278045 0.4119582773335843 1.172005925149341 1.1561018739840807 1.1032422410077494 0.2897431462530468 0.0010133941165421 0.0561990347849709 0.0056684159955205 0.00262770885776 0.0019884945269669 +Basolateral plasma membrane 19 41 2.0147257471889546 0.0439333928958531 11.907766990291265 41.713592233009706 0.4173504135492652 0.5464661760255546 5.696723454799589 5.533263026209871 1.098008793343998 0.3512755123780914 5.892434542531897e-05 0.4271480977769256 0.303304644259416 0.0215851652574667 2.4336071963900105e-06 +Cytochrome complex 6 16 1.990432740439204 0.0465432862846928 6.021844660194175 16.08495145631068 1.0267019648816196 0.2321293206617183 2.9315837025395948 1.6175814223208935 1.624269406530766 0.2919563386676546 0.0056546641425135 0.1305522111527444 0.031373049189738 0.0049571663496986 0.000373895250662 +Platelet alpha granule 6 16 1.98205877291908 0.0474726630507509 4.211165048543689 15.902912621359222 0.6039612674990132 0.4510107266729922 2.510477385063311 2.1030009215071965 0.8798256715017497 0.2887985186703408 0.0013423636387488 0.1835089509173778 0.0614247268920475 0.0808776862517318 0.0037452233271246 +Late endosome membrane 18 42 1.9784348451114036 0.0478796720433252 8.400485436893204 35.220873786407765 -0.1907871949509251 0.3412955054288843 4.360825137615114 6.285848739997517 1.5677242851178623 0.3272837423268039 1.839479876590532e-06 0.1162566833370341 0.0011140245722043 1.383236352886924e-06 5.99569383373438e-06 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2a58c82ab8752614063a1dd40cdc0ccf33b628ac --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 901, + "title": "Average number of proteins per term", + "value": 28.197558268590456 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ddb16144af07a0057404ea1bb4035bc69c580820 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cb67de398d68425378a587bc7951366161d1430b --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,313 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Intrinsic component of plasma membrane 0.703357072894725 5.122987981254324 3.007315252837149e-07 0.0002709224389107 0.000183749868948 99 Q9UNN8,Q96QD8,P55011,Q9UIQ6,P05023,O60637,Q08722,P05141,O00592,Q9BTU6,P15260,Q15043,Q99805,P36896,P05067,O14786,Q15375,O15118,P02786,P10321,P19022,P27824,O00560,P14672,Q9H1Z9,O43657,Q92673,P0DP25,P20645,P01130,Q13641,Q9UNK0,P20020,P06756,P01889,Q9NR28,P16615,Q92542,P30825,P00533,Q9NPF0,Q9H813,O96005,O00264,Q8NBJ4,O15031,P35613,P12235,P48960,P10586,Q8WTV0,P04439,Q7KYR7,P51790,P11717,Q07954,P15529,P11166,Q96J84,P11279 60 +Intrinsic component of organelle membrane 0.7120707894558753 5.065242940034482 4.078798422810086e-07 0.0003674322930591 0.000183749868948 116 P20339,O94901,O75844,L0R6Q1,O96008,O60499,Q5SNT2,O60830,Q8N4V1,Q9BUR5,Q15070,Q9Y512,O95470,Q9Y287,Q6UXV4,Q99442,Q13505,Q9Y282,Q9BUN8,Q96A33,Q99595,Q16891,O15118,P10321,P61020,P27824,Q9UG56,Q9HC21,O14925,O95070,Q9NVH1,Q9BPX6,Q9H490,Q9NQC3,Q6P4A7,P20020,O15258,Q8TB61,P01889,P57088,Q10471,Q7L0J3,Q8IWA4,Q9HCU5,Q15629,Q92643,Q9Y2R0,O43505,Q6ZRP7,Q9H3K2,Q14739,P12235,P42892,Q9P035,P04439,Q03518,Q8TCT9,O43292,O76024,Q86XL3,Q9BWH2,P51149,Q86Y82,P57105,Q9NZ01,Q5XKP0,Q9Y4P3,Q8TCT8 68 +Endocytic vesicle 0.6565024269877066 4.7843288076304455 1.7155964435744409e-06 0.0015445596596438 0.0003932715729407 87 P20339,O43493,Q16625,P04114,Q969Q5,P51148,P51151,P02786,P10321,P61020,Q93050,O15400,P42345,Q14254,P20645,P01130,Q9UNK0,P06756,P98164,P01889,Q06481,Q04656,P00533,Q14964,Q14108,P51809,Q9H223,Q8WTV0,Q9Y487,P04439,Q03518,Q9H4M9,P51790,P11717,Q07954,P51149,Q86Y82,Q5KU26,P11279,O00461,P11233 41 +Transport vesicle 0.6682242466015644 4.780806474200355 1.7459337311453993e-06 0.0015718510111557 0.0003932715729407 100 O43731,P20339,O43493,O60499,P62820,Q13277,Q9NR31,P05067,P51151,Q92572,P24390,P10321,P61020,O15400,Q9H0U4,P14672,P50897,Q92673,P0DP25,Q9Y6B6,P20645,P19021,P20020,Q8TBA6,P01889,P16870,Q9GZM5,O15126,Q7Z6M1,Q9Y3B3,Q04656,Q96A57,Q99523,Q92542,Q7L0J3,Q9BT78,P61421,P49755,O95249,Q13190,P51809,O15260,O43760,P04439,Q9NV96,P51790,P11717,O76024,Q15363,P51149,Q86Y82,P11279,O00461 53 +Cell surface 0.654705600697587 4.730299708952482 2.24188615627341e-06 0.0020179029817484 0.0004039878853606 91 Q9UNN8,Q8IX05,Q08722,Q14126,Q08431,P07858,P36896,P05067,Q5ZPR3,P07237,P19022,P02786,P10321,Q9HDC9,Q07021,P14672,Q13685,Q92673,P01130,P19021,Q13641,O15258,P06756,P98164,O75787,P01889,P08195,Q99523,P00533,Q96JJ7,Q9H813,O96005,O15031,P42892,Q8WTV0,P04439,O75955,Q7KYR7,P43121,P51790,P11717,P15529,Q8TCT9,Q4KMQ2,P11279,P11233 46 +Vacuolar lumen 0.7366856579520243 4.673312935148979 2.963796527089002e-06 0.0026668223227313 0.0004450634451513 72 P61916,O75629,P10619,Q8IV08,Q9UMR5,P04114,Q99519,P07602,P07858,P54802,P04062,O00584,P04066,O00560,P06280,P53634,Q92820,P50897,O00754,P15586,Q9UM22,Q13510,P16278,P38571,P06865,Q99538,Q8NHP8,P07686,Q9BTY2,P11117,Q14108,P17900,P10253,Q9Y251,O00462,P38435,P08236,O14773 38 +Early endosome 0.6407092811439488 4.520987107592414 6.155193724932673e-06 0.0055304967957513 0.0007922613637378 99 Q9HC07,Q9UIQ6,Q8N4V1,Q8IV08,P04114,P62820,Q15043,Q96J02,Q9BUN8,P51148,P05067,P02786,P10321,P61020,O15400,Q92673,P01130,Q13510,Q9UNK0,Q92544,P01889,Q06481,Q04656,Q96A57,Q99523,Q92542,P00533,Q92581,Q9H223,P04439,Q9NV96,O75955,P51790,P11717,Q07954,Q86Y82,Q9H4M9,P31751 38 +Coated vesicle 0.6127622430061543 4.296737626692797 1.7333014733944552e-05 0.0154958657993117 0.0019521307844106 93 O43731,O43493,Q8N511,P04114,Q9Y282,Q9NR31,P05067,P24390,P02786,P10321,P53634,P14672,O95070,Q9Y6B6,P20645,P01130,P98164,P01889,Q9Y3B3,Q04656,Q99523,P00533,Q14108,Q13190,P51809,P42892,P04439,P11717 28 +Lysosomal lumen 0.8728207829923926 4.237700544318262 2.258206844030219e-05 0.0201410766060162 0.0022607159627459 39 P61916,P10619,Q8IV08,Q9UMR5,P04114,Q99519,P07602,P07858,P54802,P04062,O00584,P04066,P06280,P50897,O00754,P15586,Q9UM22,Q13510,P16278,P38571,P06865,Q99538,Q8NHP8,P07686,P11117,Q14108,P17900,P10253,Q9Y251,O00462,P38435,P08236,O14773 33 +Golgi apparatus subcompartment 0.5811528197989161 4.0013629235752015 6.297867562565784e-05 0.0551655704251629 0.0050047752676832 90 Q9HC07,Q8NBZ7,O43493,O60499,O15127,Q9BTU6,P05067,P51151,P04062,Q9H4A5,P14672,Q8NBN3,Q14789,Q9BXS4,Q10472,Q92673,Q969E2,Q9Y6B6,P20645,Q9UID3,P19021,Q9UNK0,Q8TBA6,Q9BZG1,O15126,Q7Z6M1,Q04656,Q96A57,Q99523,Q10471,O95249,P51809,P04439,Q9NX62,P11717,Q15363,O14828,Q8WVQ1,O00461 39 +Azurophil granule 0.6499080124828176 3.993071773434899 6.522281536636143e-05 0.0570741893168808 0.0050047752676832 73 Q6IAA8,P61916,O75629,P10619,P07602,Q13277,O00584,O15400,P04066,O00560,P06280,P53634,Q92820,Q07065,O00754,P15586,Q9NQX7,P16278,P06865,Q92542,P07686,Q9BTY2,P17900,P10253,Q9NZJ7,P51809,O00462,O15260,Q9NV96,P08236,P11279 31 +Golgi membrane 0.6133727386994995 3.977080287932478 6.976661424018538e-05 0.0609268608018287 0.0050047752676832 130 Q15392,O43731,Q9HC07,L0R6Q1,O60499,Q9P2W9,P51572,Q8N4V1,Q9BUR5,Q8IV08,Q9NTJ5,P62820,Q9Y287,Q8IUH4,Q7LGA3,Q9Y282,Q9H9S5,P51151,P40616,P24390,P10321,Q9H4A5,Q96S66,O95197,Q9H0U4,P42345,Q8NBN3,O95070,Q14789,Q9BXS4,Q10472,Q92673,Q8IZA0,P49257,P33908,Q8NF37,Q8TBA6,Q969X5,O15258,Q8TB61,P01889,Q9Y3B3,Q86SF2,Q16706,Q10471,P00533,P26572,Q14964,P61019,Q14108,Q9HD26,Q9Y3E0,Q9Y678,O43505,Q6ZRP7,P49755,Q13190,O95249,P35613,O15260,P04439,Q92896,P51790,P11717,P08754,Q12907,Q15363,P11166,Q86Y82,Q16739,Q9UBF8,O00461,O00400 73 +Vacuolar membrane 0.6141658139334001 3.9688808866707537 7.221096390663817e-05 0.0629929077704614 0.0050047752676832 132 Q9HC07,Q6IAA8,Q16625,Q9Y6I9,Q9UIQ6,P10619,Q8IV08,P51798,Q8N511,Q99519,Q9BTU6,P07602,Q15043,P04062,Q15012,O15118,P98155,Q93050,O15400,Q8NHS3,Q14849,Q9BXS4,Q07065,P20645,Q9NQX7,P01130,Q9UNK0,Q9P0T7,P98164,O75787,P08195,Q99523,Q92542,P11117,Q14108,P10253,Q9Y251,Q9NZJ7,O00462,P51809,P42892,O15260,Q8WTV0,O75503,Q9Y487,Q9NV96,O75955,P51790,Q07954,Q13137,P11279,O95772,Q8TCT8,P36543 54 +Late endosome 0.6247680169681005 3.8285907561135937 0.0001288791058915 0.1096383564982828 0.0082942910291629 74 Q9HC07,Q6IAA8,Q13501,Q9BRK5,Q8IV08,P07602,Q9BUN8,Q96PU5,Q15012,O15118,O15400,P14672,Q14849,Q9BXS4,Q92673,P20645,P01130,Q9UNK0,Q9P0T7,P10644,Q99538,Q04656,Q96A57,P00533,Q14108,Q14596,Q9NZJ7,P51809,Q9NV96,P51790,P11717,P11279,O95772,Q8TCT8 34 +Side of membrane 0.5920833292607294 3.78921707901369 0.0001511228145834 0.1273074360092113 0.0090774437293098 78 P20339,Q8IX05,P62942,P10619,Q08431,P07858,P07237,Q5ZPR3,P02786,P10321,P27824,P14672,P01130,P20020,Q9H0H5,P06756,P98164,O75787,P01889,Q9NR28,P17900,O96005,P42892,P04439,O75955,Q7KYR7,P43121,P51790,Q8TCT9,P11279,Q8TCT8 31 +Endosome membrane 0.5831957530923768 3.6333588467828535 0.0002797555185725 0.2228290860733753 0.0157537326396145 133 Q9HC07,P20339,Q6IAA8,P05556,Q8N4V1,Q8IV08,P04114,Q9Y287,O15127,Q15043,Q96J02,Q99805,P51148,Q15012,O15118,P02786,P10321,P61020,Q93050,O15400,Q14849,Q9BXS4,Q92673,Q969E2,P01130,Q9UNK0,Q9P0T7,Q9H9H4,O75787,P01889,Q7Z6M1,Q06481,Q04656,Q99523,Q92542,P00533,Q15904,Q9NPF0,Q14108,Q92581,P51809,Q9H223,P42892,Q9Y487,P04439,Q9NV96,Q9H4M9,P51790,P11717,P51149,O14828,Q86Y82,P11279,O00461,O95772,Q8TCT8 56 +Pigment granule 0.6441358728178945 3.4071620274737997 0.0006564214718649 0.4465755032467335 0.0347903380088426 63 P20339,P04843,P05023,P05556,P62820,P51148,P07858,Q13277,P07237,P51151,P02786,P61020,Q93050,P27824,O00560,Q92820,O43852,P57088,P08195,Q04656,Q92542,P61019,P55209,P49755,P54709,P35613,Q15758,Q8WUM4,O75955,O14773,P11166,P11279,P51149 33 +Endocytic vesicle membrane 0.72461331492547 3.389981950709742 0.0006989722555161 0.4674051110768251 0.0349874445677823 44 P20339,O43493,P04114,P51151,P02786,P10321,Q93050,P20645,P01130,Q9BZG1,P98164,P01889,Q06481,Q04656,P00533,Q14964,Q14108,P61421,P51809,Q8WTV0,Q9Y487,P04439,Q03518,P11717,Q07954,Q5KU26,P11279,P51149 28 +Vacuole 0.6186942770947383 3.3457826854201382 0.0008205067454514 0.5226856709498389 0.0389092935606174 231 Q13501,O75629,Q8IV08,Q9UMR5,P07602,P07858,Q15012,O00584,P98155,P04066,P06280,Q14849,Q9BXS4,P50897,Q9NQX7,O00115,Q9P0T7,P16278,P06865,Q99523,Q8NHP8,Q9BTY2,P11117,P17900,Q14596,P10253,O00462,P42892,O75503,Q9NV96,P09622,Q07954,O14773,Q13137,P11279,O95772,Q8TCT8,Q9HC07,Q16625,Q9UIQ6,P10619,P04114,Q99519,Q13277,P54802,O15118,Q93050,O15400,P53634,O00560,Q92820,O00754,P15586,Q9UM22,P01130,P98164,Q99538,Q96A57,Q92542,P07686,Q14108,Q9Y251,O15260,Q9UHG3,P51790,P38435,P08236,P61916,P51798,Q8N511,Q9BTU6,P04062,Q8NCC3,Q8NHS3,Q07065,P20645,Q13510,Q9UNK0,O75787,P08195,P38571,Q9NZJ7,P51809,Q8WTV0,Q9Y487,Q9HB90,O75955,P36543,Q6IAA8,Q9Y6I9,Q969Q5,Q9NX40,Q15043 93 +Secretory granule membrane 0.5744585592727407 3.293046765116803 0.0009910798855656 0.5907404666441186 0.0424451287945365 73 Q6IAA8,Q08722,Q969Q5,P07602,Q08431,P51148,Q13277,P30519,P10321,P61020,Q93050,Q07065,Q9NQX7,P19021,P06756,O75787,P01889,P16870,Q06481,Q92542,Q96JJ7,O00264,P10253,Q9NZJ7,P51809,O00462,P35613,O15260,P48960,Q9NV96,P11717,P15529,Q15363,Q4KMQ2,P11279 35 +Recycling endosome membrane 0.7576961677723052 3.2806462969975887 0.0010356953663117 0.6068818572074408 0.0424451287945365 21 Q9H223,P01889,P02786,P10321,P04439,O15127,O14828,Q92673,Q92581,Q86Y82,Q9H4M9 11 +Early endosome membrane 0.6980021776521199 3.274957434686508 0.0010567789520925 0.6142868423835437 0.0424451287945365 47 Q9HC07,Q8N4V1,Q8IV08,Q15043,Q96J02,P10321,P61020,O15400,Q92673,P01889,Q06481,Q04656,P00533,Q92581,Q9H223,P04439,Q9NV96,P51790,Q86Y82,Q9H4M9 20 +Phagocytic vesicle membrane 0.7540859402563138 3.2646919345833103 0.0010958319059051 0.6276369369008005 0.0424451287945365 22 P20339,P51809,Q9BZG1,P10321,P01889,Q9Y487,Q93050,P04439,Q06481,Q04656,Q03518,Q14964,P11279,P51149,P51151 15 +Outer membrane 0.5256019098937634 3.251133717981689 0.0011494578147261 0.6452199192028947 0.0424451287945365 80 Q9NS69,P52789,Q8N4H5,P09601,O96008,P45880,O43169,Q9BUR5,Q9Y6C9,Q9Y512,Q6UXV4,Q13505,Q9NQZ5,P21796,Q8WY22,Q96TC7,Q16891,Q99720,P42345,Q9NVH1,Q53H12,Q9NZ45,P00387,Q07820,Q8IWA4,O00264,P50402,Q9NZJ7,Q6NUM9,P57105,O00429,Q9BWH2,O60313,Q9Y277,Q5XKP0 35 +Apical part of cell 0.6484449433491785 3.239166000516374 0.0011987978000143 0.6606640829691062 0.0424451287945365 58 Q16625,P55011,P05023,Q9Y6M7,O00592,P04920,Q15043,Q13277,P07858,P05067,Q86UE4,P19022,Q14254,P01130,P20020,O75787,P98164,P08195,Q99538,Q04656,P30825,Q9NV96,O75955,P51790,P11166,P41208,P36543 27 +Coated vesicle membrane 0.6317702422340659 3.2184760512526007 0.0012887373215182 0.6871092466851731 0.0424451287945365 61 O43731,O43493,Q8N511,P04114,Q9NR31,P24390,P02786,P10321,Q9Y6B6,P20645,P01130,P98164,P01889,Q9Y3B3,P00533,Q14108,Q13190,P51809,P04439,P11717 20 +External side of plasma membrane 0.7362842586227467 3.213090739383795 0.0013131479593684 0.6939246039929449 0.0424451287945365 29 Q8IX05,P06756,O75787,P02786,P98164,P42892,O75955,Q7KYR7,P43121,P14672,P51790,Q08431,P11279,O96005,P07858,P01130,Q5ZPR3 17 +Intrinsic component of endoplasmic reticulum membrane 0.6845841590947875 3.202884448022022 0.0013605856172058 0.7067478209757025 0.0424451287945365 48 O75844,Q8N4V1,O95470,Q9Y282,Q9BUN8,Q96A33,P10321,P27824,Q9H490,Q9NQC3,Q8TB61,P01889,P57088,Q9HCU5,Q15629,Q92643,Q9P035,P04439,Q03518,O43292,Q8TCT9,O76024,Q86XL3,Q9NZ01,Q9Y4P3,Q8TCT8 26 +Endoplasmic reticulum golgi intermediate compartment membrane 0.7404123558777279 3.201707078813921 0.00136615841847 0.7082185774052878 0.0424451287945365 25 P51572,Q8N511,Q9Y282,P24390,P53634,Q9H0U4,O95070,Q10472,P49257,Q9Y3B3,Q15904,P26572,P61019,P49755,Q13190,O15260,Q03518,Q12907,Q15363 19 +Golgi associated vesicle 0.7173009771239458 3.166475027002164 0.0015429859415849 0.7512492756196288 0.0463410111122687 35 O43731,O43493,P24390,Q9Y3B3,Q04656,Q99523,Q8N511,P14672,P11717,Q9Y287,Q8TCT8,Q8IUH4,P05067 13 +Azurophil granule membrane 0.7353127928384073 3.149787940092445 0.0016338901219155 0.7708409476734217 0.0474882258014796 22 P51809,O00462,Q6IAA8,O15260,Q9NV96,Q92542,P07602,Q07065,P11279,Q9NQX7,P10253,Q9NZJ7 12 +Recycling endosome 0.7132919315074979 3.139638461794798 0.0016915645464712 0.7824638354257596 0.0476281142615807 35 P05556,O15127,P05067,P02786,P10321,O15400,Q92673,Q969E2,Q9UID3,Q9UNK0,P01889,Q96A57,Q92581,Q9H223,P04439,P51790,O14773,O14828,Q86Y82,Q9H4M9 20 +Transport vesicle membrane 0.6824295785241139 3.112929719554743 0.0018524012381344 0.8118585618787919 0.050576167138156 45 P20339,O60499,P62820,Q9NR31,P10321,P61020,Q92673,P0DP25,Q9Y6B6,P19021,P20020,P01889,P16870,O15126,Q9Y3B3,Q7L0J3,P49755,Q13190,P51809,O43760,P04439,Q9NV96,O76024,Q15363,Q86Y82,P51149 26 +Endosome 0.5884436991218869 3.079615146595827 0.0020726823261629 0.8457876619412743 0.0547166998574596 218 O43493,Q13501,Q8IV08,Q9Y287,P07602,Q99805,P07858,P05067,Q15012,P02786,Q14849,Q9BXS4,Q92673,Q9P0T7,Q06481,Q99523,Q14596,P42892,P04439,Q9NV96,P11717,Q07954,O14773,P11279,O00461,O95772,Q8TCT8,Q9HC07,Q9UIQ6,Q9BRK5,P04114,O15127,O15118,P10321,P61020,Q93050,O15400,P01130,P10644,P98164,Q99538,Q04656,Q96A57,Q92542,Q15904,Q14108,Q92581,P35613,P51790,Q86Y82,P31751,Q8N4V1,Q9BTU6,Q96J02,Q9BUN8,Q96PU5,P14672,P20645,Q13510,Q9UNK0,Q92544,O75787,P01889,P00533,Q9NZJ7,P51809,Q9H223,Q9Y487,O75955,O14828,Q9H4M9,P36543,Q6IAA8,Q969Q5,P62820,Q9NX40,Q15043,P51148,O14786,Q14254,Q969E2,Q9H9H4,Q7Z6M1 83 +Exocytic vesicle 0.6963582899509526 3.0721105388579284 0.0021255099833641 0.8529705907381938 0.0547166998574596 38 P20339,O60499,Q13277,P05067,P61020,O15400,P50897,P0DP25,P20020,O15126,Q96A57,Q92542,Q7L0J3,Q9BT78,P61421,O43760,P51790,O76024,Q86Y82,P11279,P51149 21 +Clathrin coated endocytic vesicle membrane 0.7411901627373952 3.0357604319555636 0.0023992991766845 0.8851772999026895 0.0584540267520546 18 O43493,P98164,P02786,P00533,P11717,P04114,Q14108,P20645,P01130 9 +Intrinsic component of mitochondrial membrane 0.682392763353733 3.028340998060357 0.0024590044119603 0.8912051726697043 0.0584540267520546 41 O96008,O60830,Q9BUR5,Q15070,Q9Y512,Q6UXV4,Q13505,Q99595,Q16891,Q9UG56,Q9HC21,O14925,Q9NVH1,Q9BPX6,Q6P4A7,Q8IWA4,Q9Y2R0,Q9H3K2,P12235,Q9BWH2,P57105,Q5XKP0 22 +Golgi cisterna 0.7127610978699915 3.027565884370666 0.0024653196632387 0.8918239811516354 0.0584540267520546 25 O95249,Q8NBZ7,Q9H4A5,P04439,Q99523,Q10471,Q8NBN3,Q10472,Q9BXS4,Q92673,Q8WVQ1,Q9Y6B6,O00461 13 +Endoplasmic reticulum lumen 0.602626029356275 3.010889192584627 0.0026048389079786 0.9046329264264528 0.0599097298156055 62 O14657,O43493,Q9Y680,P04114,Q08431,P07237,P05067,P19022,P13674,O00584,P27824,P53634,O95881,Q9NZ08,Q07065,Q14257,P07942,O43852,Q02818,Q06481,Q9BTY2,Q9NWM8,Q8NBJ4,Q9BV10,O76024 25 +Presynapse 0.489018840689761 3.0045546831410466 0.0026596994368748 0.9092440907359456 0.0599097298156055 89 P20339,O60499,Q5SQN1,Q9BTU6,Q13277,P05067,P19022,P61020,P27824,O15400,Q07021,P14672,P50897,P0DP25,Q13641,P20020,Q9UQB8,O15126,Q96A57,Q92542,Q7L0J3,Q9BT78,P61421,O43760,O75955,O00429,P51790,O76024,P11166,Q96A49,Q86Y82,P07196,P11279,P51149 34 +Inner mitochondrial membrane protein complex 0.5434464068260806 2.989914589518752 0.0027905546398894 0.9193635422301168 0.0613241397692772 73 O75964,P14406,O60830,Q9BUR5,Q9Y6M9,Q96CU9,Q9P0J0,Q9Y512,Q13505,Q99595,Q16891,O14925,Q8IYU8,Q9UDW1,Q9NVH1,Q9BPX6,P03886,O75438,P03915,O14949,O96000,P00403,Q86Y39,O43676,O95169,P12236,Q3ZCQ8,P22695,Q5XKP0,P13073 30 +Snare complex 0.785658129646093 2.942336853945686 0.0032574537650398 0.9471213972316768 0.067646413204667 15 O95249,Q13190,Q9P2W9,O60499,O15400,Q86Y82,Q13277,Q9UNK0 8 +Clathrin coated endocytic vesicle 0.7011891323908348 2.941714110813911 0.0032640111109012 0.9474339078520532 0.067646413204667 23 O43493,P98164,P02786,P00533,P11717,P04114,Q14108,P20645,P01130 9 +Apical plasma membrane 0.6516501800565124 2.9320994772462825 0.0033667888523176 0.952097844931118 0.067646413204667 47 Q16625,P55011,P05023,Q9Y6M7,O00592,P04920,Q15043,Q13277,P07858,Q86UE4,P19022,Q14254,P20020,O75787,P98164,P08195,Q04656,P30825,Q9NV96,O75955,P51790,P11166,P36543 23 +Intrinsic component of mitochondrial inner membrane 0.6920960686732514 2.9263193860859724 0.0034299860516271 0.9547580093859684 0.067646413204667 29 Q16891,Q9NVH1,Q9H3K2,O60830,Q9UG56,Q9BUR5,Q9HC21,O14925,Q15070,Q9Y512,Q6UXV4,Q13505,Q9Y2R0,Q5XKP0,Q6P4A7,Q99595 16 +Endoplasmic reticulum golgi intermediate compartment 0.6417901791571462 2.8813978482174063 0.0039591554662925 0.971964376708099 0.0758978526623317 48 P80303,P51572,Q8N511,Q9Y282,P07237,P24390,P53634,Q9H0U4,O95070,Q14789,Q10472,P49257,P33908,O15258,Q969X5,Q02818,Q9Y3B3,Q15904,P26572,P61019,P49755,Q13190,O15260,Q03518,Q12907,Q15363 26 +Synaptic vesicle membrane 0.7581748308157169 2.792682817797455 0.0052272920065807 0.9911039052311904 0.0981206270401935 15 P20339,P61020,O60499,O15126,O43760,Q7L0J3,O76024,Q86Y82,P0DP25,P51149,P20020 11 +Golgi cisterna membrane 0.717518656795522 2.7741586542619765 0.0055344680195363 0.9932647865545894 0.1017664425633119 17 Q8NBZ7,Q9H4A5,Q99523,Q10471,Q8NBN3,Q10472,Q8WVQ1,Q9Y6B6,O00461 9 +Multivesicular body 0.7340186278462809 2.7596272958332846 0.0057867337659096 0.9946410710514572 0.104276942461692 16 Q9P0T7,P10644,P14672,Q92673,P11279,Q96PU5 6 +Endosome lumen 0.924891940272528 2.746617744393607 0.0060213268213233 0.9956675185910864 0.1063767738433799 7 P98164,Q9UIQ6,P04114,P07858,P05067 5 +Phagocytic vesicle 0.6447680067321752 2.7237838513041215 0.0064538729560028 0.9970730229210965 0.1084969793706751 39 P20339,P08670,P51151,P10321,Q93050,P42345,Q9UNK0,Q9BZG1,P06756,P01889,Q06481,Q04656,Q14964,P61421,P51809,Q9Y487,P04439,Q03518,P51790,Q86Y82,P11279,P51149 22 +Vesicle membrane 0.5796281651638823 2.7224697123729973 0.0064795972618794 0.9971405144866764 0.1084969793706751 265 O43731,O43493,O60499,Q8IV08,Q9Y287,P07602,Q99805,Q15012,P24390,P02786,Q14849,Q9BXS4,Q92673,Q9NQX7,P19021,Q9P0T7,P16870,Q06481,Q99523,Q7L0J3,P10253,O00462,P42892,P48960,P04439,Q9NV96,P11717,Q07954,Q5KU26,P11279,O00461,O95772,Q8TCT8,Q9HC07,Q9UIQ6,Q08722,P04114,O15127,Q13277,P30519,O15118,P10321,P61020,Q93050,O15400,P01130,P06756,P98164,Q04656,Q92542,Q15904,Q14108,Q92581,Q13190,P35613,O15260,Q03518,P51790,P15529,Q4KMQ2,Q86Y82,P11233,Q8N4V1,Q8N511,Q08431,Q8IUH4,Q96J02,Q9NR31,P14672,Q07065,P0DP25,Q9Y6B6,P20645,Q9UNK0,O75787,P01889,Q9Y3B3,P00533,Q96JJ7,O00264,Q9NZJ7,P51809,Q9H223,Q8WTV0,Q9Y487,O43760,O76024,Q15363,O14828,Q9H4M9,Q6IAA8,P55011,Q969Q5,P62820,Q15043,P51148,Q92572,Q14254,Q969E2,P20020,Q9H9H4,Q7Z6M1,Q14964 103 +Clathrin coated vesicle membrane 0.6608879095273261 2.717859151456284 0.0065705801866924 0.997366989965538 0.1084969793706751 29 O43493,P98164,P02786,P00533,P11717,P04114,Q14108,P20645,P01130 9 +Golgi associated vesicle membrane 0.6665919789883343 2.715228178725984 0.0066230120592531 0.9974892717139552 0.1084969793706751 22 O43731,P24390,Q9Y3B3,Q8N511,Q9Y287,Q8IUH4,Q8TCT8 7 +Azurophil granule lumen 0.6232575065996737 2.6934412430650685 0.00707186090331 0.9983290843562884 0.1137811906050416 46 O00584,O75629,P16278,P04066,O00560,P10619,P06280,Q92820,P53634,P07686,P08236,Q9BTY2,O00754,P15586,P17900 15 +Copii coated er to golgi transport vesicle 0.652312591002687 2.676981497923902 0.0074288737225109 0.99879153136861 0.1153987238318365 31 Q13190,P10321,P01889,P04439,Q9Y3B3,P53634,O95070,Q9Y6B6,Q9Y282,Q9NR31,P05067 11 +Specific granule membrane 0.7537995361818844 2.6751422879890367 0.0074697539807739 0.9988355551954992 0.1153987238318365 14 P30519,P06756,Q9NV96,Q08722,Q4KMQ2,Q07065,O00264 7 +Cis golgi network 0.7691080772702139 2.671263453195295 0.0075566311943155 0.99892386546777 0.1153987238318365 13 O95249,Q8TBA6,O43731,P24390,Q16706,Q14789,Q9UNK9,O00461 8 +Golgi stack 0.6429232461747059 2.631811956644486 0.0084930856024214 0.9995403066829494 0.1248182697487037 33 O95249,Q8TBA6,Q8NBZ7,Q9BZG1,Q9H4A5,P04439,Q99523,Q10471,Q8NBN3,Q14789,Q10472,Q9BXS4,Q15363,Q92673,Q8WVQ1,Q9Y6B6,O00461 17 +Trans golgi network 0.5553167360367668 2.6304220606126205 0.008527892131753 0.9995546191777648 0.1248182697487037 63 Q9HC07,O43493,O60499,Q9BTU6,O15127,P05067,P04062,Q9H4A5,P14672,Q92673,Q969E2,P20645,P19021,Q9UNK0,Q04656,Q96A57,P51809,Q9NX62,P11717,O14828 20 +Outer mitochondrial membrane protein complex 0.7111146758831479 2.6279921993703264 0.0085890485287676 0.9995786970699412 0.1248182697487037 16 Q16891,Q9NS69,Q8N4H5,O96008,Q9BUR5,Q9Y512,Q8IWA4,Q13505,Q9NVH1,Q5XKP0 10 +Clathrin coated vesicle 0.5940848857285079 2.6065810827075344 0.0091451168936564 0.9997458684098656 0.1300711246809935 52 O43493,P98164,P02786,P42892,Q04656,Q99523,P14672,P00533,P11717,P04114,Q14108,P20645,P01130 13 +Nuclear outer membrane endoplasmic reticulum membrane network 0.5790425737232465 2.6030726838301073 0.0092392363813358 0.9997667143188008 0.1300711246809935 290 Q15392,O43731,P04843,P62942,O75915,Q8IV08,Q99442,Q9Y282,Q70UQ0,Q9BRR6,P51151,Q86UE4,P24390,P43307,O95197,Q9H0U4,P42345,P35610,Q9NRX5,Q14849,Q53GQ0,Q92673,Q9Y320,Q9NQC3,O43852,Q8NF37,Q8TB61,P00387,O14678,Q96G23,Q99523,P61019,Q9H2C2,P49755,P51571,Q8TC12,P04439,O00429,P08754,Q12907,P51648,O95772,Q8TCT8,Q9BQE5,O75844,Q6UXD5,P09601,Q9P2W9,P04114,P30519,P10321,O00560,Q10472,Q9HD20,Q9H490,P16615,Q15904,Q14108,Q92581,Q15629,Q13190,P35613,O15260,Q9BV10,Q03518,P38435,Q86XL3,Q8WVQ1,Q8N4V1,Q9BUR5,Q8N511,O60725,Q9BUN8,Q4ZIN3,Q96A33,Q14534,Q9Y5M8,Q99720,O95070,Q9NZ08,Q07065,Q9Y6B6,O75787,P01889,Q15042,Q9Y3B3,Q10471,P00533,Q15005,Q6NUQ4,Q96KC8,Q96JJ7,Q92643,P67812,O00264,P27544,Q96HY6,P51809,Q14739,Q6NUQ1,Q8TCT9,O76024,Q15363,P16435,O15269,Q9NZ01,Q9Y4P3,Q8NHH9,Q96N66,Q9Y6I9,A1L0T0,Q9BT22,O95470,Q9H3N1,Q2TAA5,O14681,P27824,Q6DD88,Q16850,Q99735,P46977,P57088,Q06136,Q15800,O14735,Q9HCU5,P50402,Q6NUM9,Q9P035,O43292,Q96AG4,P48651,O00400,Q8NFQ8 134 +Trans golgi network transport vesicle 0.721190970093612 2.586843897323755 0.0096859461926579 0.9998446107411856 0.1342621156859201 15 O43493,Q99523,Q04656,P11717 4 +Golgi apparatus 0.5832869780802002 2.5494480708623626 0.0107893578035673 0.9999430897157234 0.1445946230627598 318 O43731,Q15392,O43493,L0R6Q1,P80303,O60499,Q8IV08,Q9Y287,Q7LGA3,Q9Y282,Q99805,P05067,P51151,Q8NEW0,Q15012,P24390,Q6P4E1,O95197,Q9H0U4,P06280,Q68CQ7,Q8NBN3,P42345,Q9BXS4,P50897,Q92673,Q8IZA0,Q7Z3D4,Q9NQX7,Q9UID3,P19021,O43852,Q8NF37,Q8TBA6,Q969S3,Q9BZG1,Q8TB61,Q9UQB8,P16870,Q92520,P16278,O15126,Q86SF2,Q99523,Q16706,P61019,P49815,Q9H2C2,Q5VU43,Q8IY95,Q15691,Q8NBJ4,P49755,O75503,P04439,Q9NV96,Q92896,Q9NX62,P11717,Q07954,O14773,O00429,P08754,Q12907,Q96A49,Q96M27,Q16739,O00461,Q9HC07,Q9P2W9,Q9BRK5,O15127,Q9H9S5,O15118,P10321,Q9H4A5,Q93050,P53634,Q10472,P01130,P98164,Q9GZM5,Q04656,Q96A57,Q92542,Q14108,A2RU67,O43505,Q6ZRP7,O95249,Q13190,P35613,O15260,P51790,P11166,Q86Y82,Q8WVQ1,Q8NBZ7,Q8N4V1,Q9BUR5,Q9BTU6,Q8IUH4,Q9NR31,Q96PU5,P04062,P14672,O95070,Q9UNK9,Q9Y6B6,P20645,P33908,Q9UNK0,Q92544,Q02818,P01889,Q15042,Q9Y3B3,Q10471,P00533,Q6NUQ4,P51809,Q15363,O14828,P05023,P62820,Q9NX40,Q92572,O14681,Q14789,Q969E2,O15258,Q7Z6M1,Q7RTS9,P26572,Q14964,O14735,P51149,O00400 138 +Intrinsic component of synaptic vesicle membrane 0.7858703227625479 2.5423451060065334 0.0110111393810283 0.9999535001671797 0.1445946230627598 10 P20339,P61020,O60499,Q7L0J3,O76024,Q86Y82,P51149,P20020 8 +Nuclear envelope lumen 0.903317155914868 2.540377613047107 0.0110732841191236 0.9999560597338158 0.1445946230627598 6 P05067,Q92673 2 +Lumenal side of membrane 0.7834549569085915 2.5304534004484474 0.0113915215668103 0.999967120745181 0.1466251561670873 10 P01889,P10321,P04439,P10619,Q8TCT9,Q8TCT8 6 +Presynaptic active zone 0.7090000687014807 2.5178410895788192 0.0118076580368149 0.9999775002822924 0.1493847299914643 15 P19022,P27824,O75955,Q07021,Q7L0J3,Q13277,P05067 7 +Neuromuscular junction 0.674032673541463 2.51398608179525 0.0119375144943234 0.9999800127153572 0.1493847299914643 17 P10644,Q15375,O43760,P05556,Q7L0J3,P07196,P57105,P05067 8 +Trans golgi network membrane 0.6329114082756829 2.508335271230718 0.0121301511905067 0.9999832329351144 0.1497159756526929 26 Q9HC07,Q9H4A5,O60499,Q7Z6M1,Q04656,Q9NX62,P11717,O15127,O14828,Q969E2,P20645,Q9UID3,P05067,P51151 14 +Organelle membrane contact site 0.7060918385482444 2.5012939860321466 0.012374041206572 0.9999865773188188 0.1506623125286676 15 Q96N66,Q96S66,O96008,P51572,P27824,Q9NTJ5,Q14849,Q9Y320,Q5XKP0,O95772,Q96TC7 11 +Organelle subcompartment 0.5869863706482007 2.48638566528343 0.0129048029454741 0.9999917302208006 0.1544231792640015 357 O43731,Q15392,O43493,O60499,P04843,P62942,Q8IV08,O75915,Q99442,Q9Y282,Q70UQ0,P05067,Q9BRR6,P51151,Q86UE4,P24390,P43307,O95197,Q9H0U4,P42345,Q8NBN3,Q9NRX5,Q14849,Q9BXS4,P35610,Q53GQ0,Q92673,Q9Y320,Q9UID3,Q9NQC3,P19021,O43852,Q8NF37,Q8TBA6,Q9BZG1,Q8TB61,O15126,P00387,O14678,Q96G23,Q99523,Q16706,P61019,Q9H2C2,P49755,P51571,Q8TC12,P04439,Q9NX62,P11717,O00429,P08754,Q12907,P51648,Q9UBF8,O00461,O95772,Q8TCT8,Q4J6C6,Q9BQE5,Q9HC07,O75844,Q6UXD5,Q8TCJ2,P09601,Q9P2W9,P51572,Q9NTJ5,P04114,O15127,Q9BVG9,Q9NP72,P40616,P30519,Q9UBV2,P10321,Q9H4A5,Q96S66,O00560,Q10472,Q8WWQ0,Q8N0U8,Q9HD20,P49257,Q9H490,P16615,Q04656,Q96A57,Q15904,Q14108,Q92581,Q15629,O95249,Q13190,P35613,O15260,Q9BV10,Q03518,P38435,Q86XL3,Q8WVQ1,Q8NBZ7,Q8N4V1,Q9BUR5,Q8N511,O60725,Q9BTU6,Q9BUN8,Q4ZIN3,Q96A33,Q14534,Q9Y5M8,P04062,Q99720,P14672,O95070,Q9NZ08,Q07065,Q9Y6B6,P20645,Q9UNK0,O75787,P01889,Q15042,Q9Y3B3,Q10471,P00533,Q15005,Q6NUQ4,Q96KC8,Q96JJ7,Q92643,P67812,O00264,P27544,Q96HY6,P51809,Q14739,Q6NUQ1,Q8TCT9,O76024,Q15363,P16435,O14828,O15269,Q9NZ01,Q9Y4P3,Q8NHH9,Q96N66,Q9Y6I9,A1L0T0,Q9BT22,O95470,Q9H3N1,Q2TAA5,O14681,P27824,Q6DD88,Q16850,Q14789,Q969E2,Q99735,P46977,P57088,Q7Z6M1,Q06136,Q15800,O14735,Q9HCU5,P50402,Q6NUM9,Q9P035,O43292,Q96AG4,P48651,O00400,Q8NFQ8 177 +Clathrin coated pit 0.6277353782727793 2.4782393180144786 0.0132032552646439 0.9999937025452889 0.1544952336810934 27 P98164,P02786,P98155,Q99523,Q07954,P01130,P05067 7 +Intrinsic component of golgi membrane 0.8011689421559 2.469851581090409 0.0135169120173401 0.999995270998634 0.1561376631746602 9 O15258,Q8TB61,Q10471,O95070,Q9Y282,O43505,Q6ZRP7 7 +Golgi lumen 0.9389587986519788 2.422299795437222 0.0154226212746992 0.999999171833072 0.1758959717532159 5 O00461,P05067,Q9NX62 3 +Membrane microdomain 0.5121016146526794 2.3852844883264575 0.0170659182867525 0.999999816143568 0.1898320046464694 67 P20339,Q6IAA8,P09601,P05023,P05141,P05556,O00592,Q9BTU6,P21796,P05067,P19022,P17612,O15118,O00560,P14672,Q14254,P50897,P20020,P10644,Q04656,P00533,Q9Y251,P35613,Q8WTV0,O75955,O14773,P11166,Q86Y82 28 +Specific granule 0.6035973769255025 2.3715247747092616 0.0177148590158313 0.9999998985961018 0.1946474143080983 35 P30519,P06756,Q9NV96,Q08722,P51790,Q92820,Q99519,Q4KMQ2,Q07065,Q8WVQ1,O00264,Q13277,Q9Y251 13 +Protein lipid complex 0.8560586015319194 2.3351912489235613 0.0195334320946165 0.9999999809039544 0.2112988882907123 6 P98155,P04114,Q9UHG3,P01130 4 +Autophagosome 0.6054324951175999 2.3237407261120375 0.0201393942921643 0.9999999890596256 0.2134775794969424 27 Q13501,O75787,Q9Y6I9,Q96A57,Q969Q5,Q13137,P11279,P51149,Q14596 9 +Lumenal side of endoplasmic reticulum membrane 0.7987427244349 2.31825749810287 0.0204353308096139 0.9999999916663644 0.2140957332495596 8 P01889,P10321,P04439,Q8TCT9,Q8TCT8 5 +Er to golgi transport vesicle membrane 0.6040466443034713 2.2983537185112124 0.0215416653581546 0.9999999969894516 0.2210514173594975 21 Q13190,P01889,P10321,P04439,Q9Y3B3,Q9Y6B6,Q9NR31 7 +Plasma membrane raft 0.5936248537187082 2.2274781914354356 0.0259153317564764 0.999999999946834 0.2623563360964636 20 P10644,P19022,P17612,P09601,Q8WTV0,O75955,Q14254,P11166 8 +Tim23 mitochondrial import inner membrane translocase complex 0.828840563609303 2.214705542183876 0.0267802822128617 0.9999999999761208 0.2651542227888841 6 O60830,Q99595,P12236 3 +Blood microparticle 0.6341905236869797 2.169945383252802 0.030010983723556 0.9999999999988064 0.284630487736042 16 Q08380,P02786,O00560,P38435,P11166 5 +Endoplasmic reticulum 0.5662987315300845 2.1440998301067022 0.0320248886894005 0.9999999999998164 0.2929697796013872 470 O43731,Q15392,O43493,Q13501,P80303,P04843,P62942,Q8IV08,O75915,Q99442,Q9Y282,Q70UQ0,Q9Y2B0,P05067,Q9BRR6,P51151,Q86UE4,O60506,P24390,P43307,O00584,O95197,Q9H0U4,P42345,P35610,Q9NRX5,Q14849,Q53GQ0,Q92673,Q9Y320,Q14257,Q9NQC3,O43852,Q8NF37,Q8TB61,Q9UQB8,P00387,Q06481,O14678,Q96G23,Q99523,Q7L0J3,Q9BTY2,P61019,Q9H2C2,Q8IY95,Q8NBJ4,P49755,P51571,Q8TC12,O75503,P04439,Q9NV96,Q8WUM4,O00429,P08754,Q12907,Q32P28,P51648,Q9UBF8,O95772,Q8TCT8,Q9BQE5,O75844,Q6UXD5,Q9Y680,Q8TCJ2,P09601,Q9P2W9,P51572,Q14145,P10619,Q9BRK5,Q8TED1,Q9NTJ5,P04114,O15173,Q9H9S5,O95302,P30519,O15118,P10321,P53634,O00560,Q10472,Q9HD20,Q9H490,Q13641,P98164,P16615,Q04656,Q96A57,Q92542,Q15904,Q9H8H3,Q14108,Q92581,Q15629,Q13190,P35613,O15260,Q9BV10,P48723,Q03518,P38435,Q86XL3,Q8WVQ1,P52789,P61916,Q8N4V1,Q9BUR5,Q8N511,O60725,Q08431,Q8IUH4,Q9BUN8,Q4ZIN3,Q9NR31,Q96A33,Q14534,Q9Y5M8,P04062,Q99720,P14672,O95070,Q9NZ08,Q9UNK9,Q07065,Q9Y6B6,P07942,P33908,Q13510,Q9UNK0,Q02818,O75787,P01889,Q15042,Q9Y3B3,Q10471,P00533,Q15005,Q6NUQ4,Q96KC8,Q96JJ7,Q92643,P67812,O00264,P27544,Q96HY6,P51809,Q14739,Q9H223,Q6NUQ1,Q8TCT9,O76024,Q15363,P16435,O15269,Q9NZ01,Q9Y4P3,Q8NHH9,O14657,Q96N66,Q9Y6I9,A1L0T0,P05023,Q9BT22,O95470,P62820,Q9H3N1,Q2TAA5,P07237,P19022,O14681,P13674,Q92791,P27824,Q6DD88,Q16850,O95881,Q01105,Q99735,P46977,O15258,P57088,Q06136,Q15800,Q9NPF0,O14735,Q9HCU5,Q9NWM8,P50402,O95169,Q6NUM9,Q9P035,Q15293,O43292,Q96AG4,P48651,O00400,Q8NFQ8 201 +Microbody membrane 0.5791861655722617 2.132352520839161 0.0329778774331206 0.9999999999999244 0.2929697796013872 25 Q5T8D3,O43808,P40855,O75381,P39210,Q15067,O14678,Q14596,P50542,P28288,P51648,Q8TB36,Q7Z434 13 +Integral component of synaptic vesicle membrane 0.8099770265835337 2.1302046647184887 0.0331547201228328 0.999999999999936 0.2929697796013872 6 O60499,Q7L0J3,O76024,Q86Y82,P20020 5 +Pore complex 0.7315730048761059 2.1300632707733427 0.0331663901435532 0.9999999999999366 0.2929697796013872 9 P12235,P45880,P05141,P21796,Q9Y277 5 +Receptor complex 0.5754747468483419 2.1257165254393144 0.0335268701016595 0.9999999999999548 0.2932787374912161 30 Q15375,P06756,O15031,P02786,P98155,O00560,Q07954,P01130,Q14596,P36896,P05067 11 +Respirasome 0.5545773026239635 2.1003259358750506 0.0357001792725946 0.999999999999994 0.3045876516075176 43 P14406,Q9Y6M9,Q7KZN9,Q9P0J0,Q15526,Q9UDW1,P03886,O75438,P03915,O14949,Q13423,O96000,P00403,Q86Y39,O43676,Q6DKK2,O95169,P22695,P13073 19 +Triglyceride rich plasma lipoprotein particle 0.913086257789433 2.067331653934954 0.0387029135163936 0.9999999999999996 0.31526620487002 4 P98155,P04114,Q9UHG3 3 +Copi coated vesicle membrane 0.6545365292745462 2.046487925421765 0.0407083892437867 1.0 0.32748445275582 13 O43731,Q9Y3B3,P24390,Q8N511 4 +Calcium channel complex 0.7395593083580904 2.0355697006336895 0.0417935828996938 1.0 0.3284133724076394 8 P17612,P62942,Q8IYU8,P0DP25,Q9BPX6 5 +Chloride channel complex 0.7874789060859254 2.0283561142883606 0.0425239157005581 1.0 0.3284133724076394 6 Q9H813,Q9C0H2,Q4KMQ2 3 +Basolateral plasma membrane 0.5474011916717054 2.0147257471889546 0.0439333928958531 1.0 0.3284133724076394 41 P55011,P05023,Q9Y6M7,P04920,Q15043,P19022,P02786,Q14254,P01130,P20020,P08195,Q04656,P30825,P00533,P54709,P35613,O75955,Q07954,P11166 19 +Cytochrome complex 0.605150511476174 1.990432740439204 0.0465432862846928 1.0 0.3370280039924689 16 O14949,P14406,P00403,Q7KZN9,Q9UDW1,P13073 6 +Platelet alpha granule 0.6038101055087068 1.98205877291908 0.0474726630507509 1.0 0.3370280039924689 16 P51809,Q8NBX0,Q9NUQ9,Q06481,Q96JJ7,P05067 6 +Late endosome membrane 0.5411712210448107 1.978434845111403 0.0478796720433252 1.0 0.3370280039924689 42 Q9HC07,Q9P0T7,P51809,Q15012,Q6IAA8,O15118,Q9NV96,Q8IV08,P51790,Q14849,Q9BXS4,Q14108,Q92673,Q15043,P11279,O95772,Q8TCT8,Q9UNK0 18 +Proton transporting v type atpase complex 0.659860386119617 1.9503749840750688 0.0511314412494714 1.0 0.3543802197367213 11 O75787,Q9Y487,Q93050,Q8N511,Q15904 5 +Mib complex 0.6664909983098974 1.932654607211292 0.0532787605851798 1.0 0.3595431083933347 10 Q16891,Q9NVH1,Q9BUR5,Q9Y512,Q13505,Q5XKP0 6 +Copi coated vesicle 0.6216129929591195 1.9278675017542863 0.0538716089157604 1.0 0.3595431083933347 14 O43731,Q9Y3B3,P24390,Q8N511 4 +Brush border membrane 0.7162900212978897 1.9218528725331003 0.0546242732362656 1.0 0.3610278144839066 8 Q04656,P98164 2 +Endoplasmic reticulum tubular network 0.6414940564194886 1.9077593937409092 0.056422321259038 1.0 0.3610278144839066 12 Q15042,Q6DD88,Q9H2C2,Q9NQC3,Q8NHH9 5 +Phagophore assembly site 0.7388534874653613 1.9048654662946427 0.0567975612745357 1.0 0.3610278144839066 7 Q13501,Q9Y4P8,Q86Y82,P51149,Q14596 5 +Golgi medial cisterna 0.8116055767772079 1.8859693827941728 0.0592990806306634 1.0 0.3709601533692896 5 P04439,Q9BXS4 2 +Multivesicular body membrane 0.7067853547936215 1.874990704107228 0.0607940024013564 1.0 0.3709601533692896 8 Q92673 1 +Autophagosome membrane 0.6120360544715024 1.8711222051915897 0.0613281444455602 1.0 0.3709601533692896 14 O75787,Q9Y6I9,Q13137,P11279,P51149 5 +Acrosomal membrane 0.8592981305345964 1.8500145622480395 0.0643114507663489 1.0 0.3779057550712592 4 P15529,P35613,Q08431 3 +Intrinsic component of mitochondrial outer membrane 0.6500489175239048 1.8451211500014144 0.0650199172159959 1.0 0.3779057550712592 10 O96008,Q9BWH2,Q8IWA4,Q15388,P57105,Q8IXI1 6 +Micos complex 0.8014519468524839 1.841898172713854 0.0654900459618395 1.0 0.3779057550712592 5 Q16891,Q5XKP0,Q9BUR5 3 +Intrinsic component of presynaptic membrane 0.8547064611347925 1.8312639640745885 0.0670611535696834 1.0 0.3779057550712592 4 P27824,P19022,Q92542 3 +Presynaptic active zone membrane 0.8547064611347903 1.8312639640745765 0.0670611535696852 1.0 0.3779057550712592 4 P27824,Q13277,P19022 3 +Zymogen granule 0.7969160104986915 1.822151101780351 0.0684320616907161 1.0 0.3786120037103471 5 P49755,Q15363,O15126,Q13277 4 +Postsynaptic density membrane 0.7424029519892359 1.8208604186426969 0.0686280772641283 1.0 0.3786120037103471 6 Q15375,Q99720 2 +Presynaptic membrane 0.5772341701418182 1.81443659321358 0.0696105362944734 1.0 0.3786120037103471 16 P19022,P27824,Q92542,Q9BTU6,Q13277 5 +Tertiary granule membrane 0.6338554238839178 1.8082560080245915 0.0705666652591308 1.0 0.3807219484938733 11 P10253,Q08722,Q4KMQ2 3 +Endolysosome 0.6317086106084184 1.7964241837606048 0.0724270805256377 1.0 0.3846340233151031 11 P07858,P01130 2 +Membrane protein complex 0.5116802268260809 1.79551014896884 0.0725724572292647 1.0 0.3846340233151031 283 Q9NS69,O94901,Q8N4H5,O96008,P04843,P14406,P62942,P05556,O60499,O60830,Q96CU9,Q9Y512,Q5SQN1,Q9C0H2,Q6UXV4,Q13505,P36896,Q99595,P17612,P02786,P08069,Q53GQ0,Q53H12,O14949,O14678,Q86Y39,P04899,O43676,P56134,Q9H813,P61421,P49755,P51571,P12235,P12236,P04439,P11717,Q07954,P08754,Q96CW1,O43633,Q14344,P45880,Q9P2W9,P21796,Q13277,P10321,Q93050,O15400,O00560,O14925,Q9UDW1,Q9H490,O75438,P06756,Q92542,Q15904,O95249,Q13190,Q03518,Q4KMQ2,Q86Y82,Q9Y277,Q5XKP0,O75964,Q8N4V1,Q9BUR5,P51798,Q8N511,Q9Y6M9,Q9BUN8,Q9NR31,Q9Y5M8,P0DP25,Q9Y6B6,P03886,Q9UNK0,O75787,P01889,P08195,Q9Y3B3,P00533,Q15005,Q92643,P67812,P51809,Q9Y487,O75955,Q8TCT9,O15269,P13073,P36543,Q6IAA8,P05023,P05141,Q9P0J0,Q16891,Q92572,P19022,Q14254,Q8IYU8,Q9NVH1,Q9BPX6,P46977,P03915,Q9H9H4,Q9NR28,O96000,P00403,Q8IWA4,O95169,P54709,Q3ZCQ8,P22695,O43292 115 +Smooth endoplasmic reticulum 0.6266743227145191 1.7686198263043993 0.0769573398446261 1.0 0.4008009433526484 11 O00264,P04114,P05067 3 +Sarcolemma 0.5279416461286 1.7641302295359529 0.0777100560175831 1.0 0.4023951751255313 26 Q96QD8,P19022,P35613,P05023,P05556,O75955,Q92542,P14672,P11166,P11279,Q9H9S5 11 +Caveola 0.5809055098170497 1.756691307297656 0.0789704400073267 1.0 0.4042748093556899 15 Q8WTV0,P09601,O75955,Q14254,P11166 5 +Postsynaptic specialization membrane 0.6310847361919782 1.7431054075680434 0.0813152042158202 1.0 0.409301670382425 10 Q15375,P19022,Q99720 3 +Proton transporting two sector atpase complex proton transporting domain 0.6251655595220771 1.7110363626575946 0.0870744004080599 1.0 0.433447705898685 10 O75787,O75964,Q9Y487,Q93050,P56134 5 +Mitochondria associated endoplasmic reticulum membrane 0.6472896302163365 1.6996843633516543 0.0891903121187014 1.0 0.4367416914073369 9 Q96N66,Q96S66,O96008,P51572,P27824,Q9Y320 6 +Organelle envelope lumen 0.5127755755767294 1.6892236230433548 0.0911765835777338 1.0 0.4396082602503854 36 Q16891,O00584,O14925,P11717,O95831,Q8IYU8,O60313,Q92673,Q9BPX6,Q14596,P05067 11 +Endoplasmic reticulum exit site 0.529362576560812 1.6794360262145185 0.0930670970203673 1.0 0.4436690709806928 18 P04439,P04114,Q9HCU5,Q9Y6B6,Q9NR31 5 +Nuclear inner membrane 0.5143642301182507 1.672103928224207 0.0945038301611309 1.0 0.4464110394100952 20 O94901,O75844,Q14739,Q99720,Q9H1E5,P50402 6 +Basement membrane 0.7625609287456138 1.6714481359697626 0.0946331948139047 1.0 0.4464110394100952 5 P14543,Q5SZK8 2 +Organelle inner membrane 0.4666326056676816 1.6479644666258606 0.0993599630411086 1.0 0.4638514336789578 212 Q567V2,O94901,O75844,O75964,O96008,P39210,P14406,O60830,Q5SNT2,Q9UDX5,Q70HW3,Q9BUR5,Q7KZN9,Q15070,Q9Y512,Q96CU9,Q5T9A4,Q9Y6M9,P53701,Q9Y6C9,Q13505,Q9P0J0,Q15526,Q99595,Q16891,Q9NVI7,Q99720,Q9UG56,Q9HC21,O14925,O95831,Q8IYU8,Q9Y619,Q9UDW1,Q9NVH1,Q9BPX6,P03886,O75438,Q6P4A7,P03915,O14949,P05141,Q13423,Q6NUK1,O96000,P00403,Q9H1E5,Q86Y39,Q7Z7H8,O43676,Q9Y2R0,P23786,Q9H2D1,Q6DKK2,P50402,Q9BSK2,O95169,Q9H3K2,Q14739,P12235,P12236,Q3ZCQ8,Q9UBX3,P22695,Q9H061,Q8NBN7,O60313,O95202,Q5XKP0,P13073 70 +Low density lipoprotein particle 0.9127868852458992 1.6366884039174123 0.1016955931614256 1.0 0.4681168994725067 3 P04114,P01130 2 +Mhc class i peptide loading complex 0.807305921363679 1.636034767756926 0.1018323110950181 1.0 0.4681168994725067 4 P04439 1 +Vacuolar proton transporting v type atpase v0 domain 0.8019022630370494 1.6136005382626333 0.1066141000298108 1.0 0.4792342742421526 4 Q93050,O75787,Q9Y487 3 +Proton transporting v type atpase v0 domain 0.8019022630370494 1.6136005382626333 0.1066141000298108 1.0 0.4792342742421526 4 Q93050,O75787,Q9Y487 3 +Zymogen granule membrane 0.8015742866513487 1.612237817607353 0.1069101988042982 1.0 0.4792342742421526 4 O15126,Q13277,Q15363 3 +Secondary lysosome 0.96066863323501 1.589109313157637 0.1120357155504945 1.0 0.4829865057942371 2 Q13501 1 +Autolysosome 0.96066863323501 1.589109313157637 0.1120357155504945 1.0 0.4829865057942371 2 Q13501 1 +Respiratory chain complex iv 0.623954179304684 1.577002421230013 0.1147949679609663 1.0 0.4861684230340372 9 P14406,P13073,P00403 3 +Dendritic shaft 0.7412308260316046 1.5769330109155564 0.1148109398547441 1.0 0.4861684230340372 5 Q96J84,P05067 2 +Basal part of cell 0.4824317697459549 1.5751753476734938 0.1152159758550575 1.0 0.4861684230340372 48 P55011,P05023,Q9Y6M7,P04920,Q15043,P19022,P02786,Q14254,P01130,P20020,P08195,Q04656,P30825,P00533,P54709,P35613,O75955,Q07954,P11166 19 +Ciliary base 0.6884710902811544 1.5668963073107172 0.1171389309564439 1.0 0.4861684230340372 6 P10644,O75386,A0AVF1 3 +Ciliary transition zone 0.6682520704546598 1.563617367292445 0.1179074538078115 1.0 0.4861684230340372 7 Q15555,P41208,A6NIH7 3 +Mhc protein complex 0.8940983606557321 1.562502389934109 0.1181696832901821 1.0 0.4861684230340372 3 P04439,P10321 2 +Mhc class i protein complex 0.8940983606557321 1.562502389934109 0.1181696832901821 1.0 0.4861684230340372 3 P04439,P10321 2 +Mitochondrial permeability transition pore complex 0.7369481320327571 1.5578758954643752 0.1192626702661883 1.0 0.4884348450447076 5 P12235,P21796 2 +Sarcoplasm 0.5327697158737069 1.5274240530798362 0.1266555991053313 1.0 0.5048358659864852 16 P52789,P16615,O43852 3 +Acrosomal vesicle 0.4931467910054073 1.5223594684560855 0.1279190347949363 1.0 0.5048358659864852 19 Q9H0H5,P35613,P45880,Q9Y487,P09622,P07686,P15529,Q08431 8 +Proton transporting two sector atpase complex 0.49450894079298 1.5210947619206543 0.1282360587740583 1.0 0.5048358659864852 22 O75787,O75964,Q9Y487,Q93050,Q8N511,Q15904 6 +Cop9 signalosome 0.6362840448333302 1.5202584423376375 0.1284460342699847 1.0 0.5048358659864852 8 Q99627,Q9BT78 2 +Plasma membrane protein complex 0.4302753166300803 1.513903938222714 0.1300502051526795 1.0 0.5050656674248459 66 P62942,P05023,P05556,P36896,P19022,P02786,P10321,O00560,Q14254,P08069,P0DP25,P06756,P01889,Q9NR28,P08195,O14678,Q92542,P00533,P04899,P61421,P49755,P54709,P04439,O75955,P08754,Q07954,Q96CW1 27 +Perinuclear region of cytoplasm 0.4408175679873279 1.4975489586684416 0.1342504764277601 1.0 0.5125410138195418 188 Q9UNN8,Q9UNS2,O75569,P09601,O60499,Q9UIQ6,P05556,Q12834,Q5SQN1,P07858,P05067,Q8NEW0,Q86UE4,O15118,P17612,P02786,Q93050,O15400,Q9H0U4,P14672,O95831,Q14254,Q10472,Q9UNK9,Q07065,Q86UE8,Q01105,P20645,P07942,Q9NQX7,P19021,Q9UNK0,Q9BZG1,P16278,Q99538,Q04656,Q99523,Q10471,P00533,P26572,P49815,Q8IY95,Q9H223,P42892,Q99627,Q9Y487,O75503,Q9H4M9,O00429,P11717,Q13137,Q96A49,Q96J84,P11279,O75935 55 +Schaffer collateral ca1 synapse 0.5380936943227147 1.4877492659217817 0.1368170298233952 1.0 0.5142895969957353 15 P35222,Q15375,Q9UQB8,O60716,P05556,P47756,Q16352,P07196,Q13277 9 +Secretory granule 0.4685224366323661 1.4819749921265233 0.1383469492150286 1.0 0.5142895969957353 240 Q6IAA8,P61916,O75629,P45880,Q9Y6I9,Q08722,P10619,Q969Q5,Q99519,P07602,Q08431,Q13277,P07858,P05067,P30519,Q08380,P10321,P61020,O00584,Q93050,O15400,P04066,P53634,P06280,O00560,Q92820,P14672,O00754,Q07065,P15586,Q9NQX7,P19021,Q13510,Q9H0H5,P06756,O75787,P01889,P16870,P16278,P06865,Q06481,Q9NUQ9,Q04656,Q92542,P07686,Q9H8H3,Q9BTY2,Q96JJ7,P17900,O00264,P10253,Q9Y251,Q9NZJ7,O00462,P51809,P35613,P42892,P48960,O15260,Q8NBX0,Q9Y487,Q9NV96,P09622,P51790,P11717,P15529,P08236,O76024,Q15363,Q4KMQ2,Q8WVQ1,P11279 72 +Secretory vesicle 0.4805077483056549 1.4814239528366242 0.1384936357818988 1.0 0.5142895969957353 266 O75629,O60499,P07602,P07858,P05067,O00584,P04066,P06280,P50897,Q9NQX7,P19021,P16870,P16278,P06865,Q06481,Q7L0J3,Q9BTY2,P17900,P10253,O00462,P42892,P48960,Q9NV96,P09622,P11717,P11279,P45880,Q08722,P10619,Q99519,Q13277,P30519,Q08380,P10321,P61020,Q93050,O15400,P53634,O00560,Q92820,O00754,P15586,P06756,Q9NUQ9,Q04656,Q96A57,Q92542,P07686,Q9H8H3,Q9BT78,Q9Y251,P35613,O15260,P51790,P15529,P08236,Q4KMQ2,Q86Y82,Q8WVQ1,P61916,Q08431,P14672,Q07065,P0DP25,Q13510,Q9H0H5,O75787,P01889,Q96JJ7,O00264,Q9NZJ7,P51809,Q8NBX0,Q9Y487,O43760,O76024,Q15363,Q6IAA8,Q9Y6I9,Q969Q5 80 +Endolysosome lumen 0.9344477220583494 1.480462955140305 0.1387497398679826 1.0 0.5142895969957353 2 P07858 1 +Nadh dehydrogenase complex 0.48912373717557 1.4784967206157222 0.1392748742141614 1.0 0.5142895969957353 23 O96000,Q9Y6M9,Q9P0J0,Q86Y39,O43676,P03886,O75438,O95169,P03915 9 +Photoreceptor connecting cilium 0.711197477843502 1.4427826291511578 0.1490817140034481 1.0 0.5341073921944289 5 P41208 1 +Transporter complex 0.452470361238628 1.4332822145233626 0.1517772025939949 1.0 0.5348010316653354 55 P62942,P05023,P51798,Q9Y6M9,Q96CU9,Q9P0J0,Q9C0H2,P17612,Q8IYU8,Q9UDW1,P0DP25,Q9BPX6,P03886,O75438,P03915,O14949,O14678,O96000,Q86Y39,O43676,Q9H813,O95169,P54709,Q9NV96,P22695,Q4KMQ2 26 +Endoplasmic reticulum tubular network membrane 0.8609836065573744 1.4306238404793477 0.1525380510297329 1.0 0.5348010316653354 3 Q9NQC3,Q8NHH9 2 +Microvillus membrane 0.7048048373865358 1.414088344523985 0.1573359649147467 1.0 0.5398383912436167 5 O00592 1 +Intrinsic component of presynaptic active zone membrane 0.8544262295081958 1.4044695577063877 0.1601790706230041 1.0 0.5410554951390797 3 P27824,P19022 2 +Integral component of presynaptic active zone membrane 0.8544262295081958 1.4044695577063877 0.1601790706230041 1.0 0.5410554951390797 3 P27824,P19022 2 +Microvillus 0.4768268998318389 1.3936643109633318 0.1634189982333511 1.0 0.5427935015651815 21 Q8IX05,P06756,Q04656,O00592 4 +Anchored component of synaptic vesicle membrane 0.7471302066251063 1.384579116480616 0.1661812007795999 1.0 0.5430171939684257 4 P20339,P51149,P61020 3 +Neurofilament 0.7468022302394154 1.3832005714166262 0.1666033745849464 1.0 0.5430171939684257 4 P07196,Q16352,O14786 3 +Platelet alpha granule lumen 0.5575823575033287 1.3791863794479713 0.1678372964715444 1.0 0.5439618853268401 11 Q9Y6I9,P05067,Q8NBX0,Q9NUQ9 4 +Plasma membrane region 0.4273743941172967 1.3712915298420498 0.1702840950541102 1.0 0.5449123598356977 182 Q16625,P09601,P55011,P05023,P05556,Q9Y6M7,O00592,P04920,Q9BTU6,Q15043,Q13277,P07858,O14786,P05067,Q86UE4,Q15375,P40855,P17612,P02786,P19022,P98155,P27824,Q99720,P14672,P08069,Q14254,P01130,P20020,P10644,Q9H0H5,Q9BZG1,Q9UQB8,P06756,P98164,O75787,P08195,Q06481,Q04656,Q99523,Q92542,P30825,P00533,Q15691,P61421,P54709,P35613,Q15758,Q8WTV0,Q9H4M9,Q9NV96,O75955,P57105,O00429,P51790,Q07954,P11166,Q96A49,P11233,O75935,Q96CW1,P31751,P36543 62 +Photoreceptor inner segment 0.6270779708384235 1.3598309833124576 0.1738834153014303 1.0 0.5536005554296423 7 P35613,Q15555,P11166 3 +Vesicle lumen 0.3863973142144647 1.3377447415439483 0.1809796606418319 1.0 0.5654518116239367 127 O75629,P10619,P04114,Q99519,P05067,Q08380,O00584,P04066,P53634,P06280,O00560,Q92820,O00754,P15586,P16278,Q9NUQ9,P07686,Q9BTY2,P17900,Q9Y251,P08236,Q8WVQ1 22 +External encapsulating structure 0.4666364095838813 1.3368038780657712 0.1812866630015757 1.0 0.5654518116239367 39 Q08380,Q9NZJ7,P53634,Q5SZK8,Q92896,P14543,P07602,Q08431,Q5KU26,P07942,P07858,Q9Y251 12 +Derlin 1 retrotranslocation complex 0.7280008658854915 1.3040844732505716 0.1922047822257424 1.0 0.5857345288259825 4 Q9BUN8,Q8TCT9 2 +Intrinsic component of postsynaptic specialization membrane 0.8282481622912405 1.300037477346868 0.1935881246037905 1.0 0.5857345288259825 3 Q15375 1 +Platelet alpha granule membrane 0.8882333661094842 1.2893443609446422 0.1972783952031933 1.0 0.5866265151091657 2 Q06481 1 +Early phagosome 0.8225110480121012 1.2771621283445358 0.2015450143619317 1.0 0.5928338153505527 3 Q06481 1 +9plus0 non motile cilium 0.5462382910375349 1.2740216806392484 0.2026557326614542 1.0 0.5928338153505527 10 P35613,Q15555,P41208 3 +Gtpase complex 0.7192522138405971 1.2672254972143278 0.205074671315198 1.0 0.5967500848265247 4 Q14344,P04899,P08754 3 +Anchored component of membrane 0.5871257070605012 1.2664449287511752 0.2053538341886871 1.0 0.5967500848265247 8 P51149,P61020 2 +Phagophore assembly site membrane 0.8183606557377021 1.260619735707533 0.2074458846204914 1.0 0.5975724724167517 3 P51149,Q9Y4P8 2 +Integral component of cytoplasmic side of endoplasmic reticulum membrane 0.8800393313667758 1.2556004656743305 0.2092608624597294 1.0 0.5975724724167517 2 Q8TCT8 1 +Uniplex complex 0.8138218398771018 1.2425367572065085 0.2140385873665293 1.0 0.5975724724167517 3 Q8IYU8 1 +Platelet dense tubular network 0.8767617174696894 1.242121481896351 0.2141917437523417 1.0 0.5975724724167517 2 P16615 1 +Platelet dense tubular network membrane 0.8767617174696894 1.242121481896351 0.2141917437523417 1.0 0.5975724724167517 2 P16615 1 +Pole plasm 0.664697620019495 1.2332395448937297 0.2174864055877976 1.0 0.5975724724167517 5 Q9Y2W6 1 +Cortical endoplasmic reticulum 0.8109300597057731 1.2310205068171078 0.2183151946178716 1.0 0.5975724724167517 3 Q9H2C2 1 +Atpase dependent transmembrane transport complex 0.8085245901639317 1.221444157971185 0.2219178965552022 1.0 0.5975724724167517 3 P54709,P05023 2 +Endoplasmic reticulum protein containing complex 0.4239793991389777 1.2020370202699482 0.2293491852606375 1.0 0.6095681885540838 57 Q8TCJ2,P04843,P62942,Q8N4V1,Q9BUN8,P07237,Q9Y5M8,Q9UBV2,P13674,P14314,Q53GQ0,Q9H490,P46977,Q15005,Q92643,P67812,P51571,P04439,Q03518,Q6NUQ1,O43292,Q8TCT9,O15269 23 +Semaphorin receptor complex 0.8652900688299058 1.19504195671582 0.2320706378508106 1.0 0.6102066802297057 2 O15031 1 +Cell body membrane 0.85414618157981 1.1494757745738315 0.2503598504168458 1.0 0.6277482246291154 2 P55011 1 +Dendritic spine membrane 0.8541461815798093 1.1494757745738284 0.2503598504168471 1.0 0.6277482246291154 2 O75787 1 +Perikaryon 0.4444148907849855 1.1460452239618126 0.2517764403071405 1.0 0.6277482246291154 22 P19021,Q9BTU6,P05067,Q04656 4 +Lipid droplet 0.4469663271988188 1.145968845686996 0.2518080429540548 1.0 0.6277482246291154 31 Q8NF37,Q8NBX0,Q15042,O43760,P51572,Q99720,P00387,P04114,Q9H8H3,P51149,Q01105,Q07065,Q9H4M9,P51148 14 +Protein complex involved in cell adhesion 0.7875366723832864 1.138052746106688 0.2550984580306112 1.0 0.6297087963988514 3 P06756 1 +Integrin complex 0.7875366723832864 1.138052746106688 0.2550984580306112 1.0 0.6297087963988514 3 P06756 1 +Intrinsic component of nuclear inner membrane 0.5797523230496185 1.1225651610246934 0.2616222186838142 1.0 0.6353682453749774 7 O94901,Q14739 2 +Cell pole 0.7810540663572534 1.112371712456552 0.2659783619213993 1.0 0.6433450982640282 3 Q9BTU6 1 +Cation transporting atpase complex 0.8430022943297277 1.1041081252920664 0.2695462370353572 1.0 0.6441940572118218 2 P05023 1 +Sodium potassium exchanging atpase complex 0.8430022943297277 1.1041081252920664 0.2695462370353572 1.0 0.6441940572118218 2 P05023 1 +Postsynaptic density intracellular component 0.6792390947851679 1.098653975158463 0.2719190249849026 1.0 0.6452569535723175 4 P35222,O60716,Q9UQB8 3 +Glial cell projection 0.6791776656181653 1.0983955831500674 0.2720317902261819 1.0 0.6452569535723175 4 P05067 1 +Filopodium 0.440817070121165 1.097493019084809 0.2724259307417738 1.0 0.6452569535723175 32 Q8IX05,P05067,O00592 3 +Non motile cilium 0.4934833346852911 1.090971465605483 0.2752854385306618 1.0 0.6471071501879568 13 O75386,P35613,Q15555,P41208 4 +9plus2 motile cilium 0.4345964085887367 1.08981960872751 0.2757926145085188 1.0 0.6471071501879568 19 P10644,P54709,Q13501,P05023,P41208 5 +Signal peptidase complex 0.7721311475409698 1.0770996728582196 0.281435739221012 1.0 0.652508285545038 3 P67812,Q15005 2 +Chitosome 0.8344804981973262 1.0695709011731775 0.2848124989612226 1.0 0.652508285545038 2 Q04656 1 +Lamellar body 0.834480498197315 1.0695709011731331 0.2848124989612426 1.0 0.652508285545038 2 Q07065 1 +High density lipoprotein particle 0.7697692112120612 1.0677795885993486 0.2856199473905256 1.0 0.652508285545038 3 P04114 1 +Gpi anchor transamidase complex 0.6274143762790352 1.064549310337615 0.2870799287567878 1.0 0.652508285545038 5 Q9H490,Q92643 2 +Postsynaptic endosome 0.8321861684693668 1.0602978982460571 0.2890090951160964 1.0 0.652508285545038 2 Q86Y82 1 +Excitatory synapse 0.6700557559855576 1.0600547994717084 0.2891196696205134 1.0 0.652508285545038 4 Q7L576,Q15334,Q9UQB8 3 +Neuron projection terminus 0.4783650779103909 1.04678025120832 0.2952009407942531 1.0 0.6550313093565209 14 P20339,Q7L576,Q9UQB8,P51790,Q13641,P61421 6 +Specific granule lumen 0.4476453094426684 1.0260233590698895 0.3048805736246178 1.0 0.6635202822120306 17 Q9Y251,Q99519,Q92820 3 +Mmxd complex 0.7562006029251838 1.014394334922815 0.3103946264147783 1.0 0.6722729769223925 3 P05141 1 +Platelet dense granule lumen 0.809570632579501 0.9695614739942924 0.3322651242304602 1.0 0.6884387681779623 2 Q08380 1 +Platelet dense granule 0.809570632579501 0.9695614739942924 0.3322651242304602 1.0 0.6884387681779623 2 Q08380 1 +Dendrite membrane 0.7439036154607317 0.9662796546440178 0.3339042638110649 1.0 0.6884387681779623 3 O75787 1 +Postsynaptic specialization intracellular component 0.6046287797941671 0.9617030229305518 0.3361988034465417 1.0 0.6914908496981165 5 P35222,O60716,Q9UQB8 3 +Respiratory chain complex iii 0.5437346848582016 0.9411803759688152 0.3466124314862067 1.0 0.7017928107170163 7 O14949,Q9UDW1 2 +Gamma secretase complex 0.8010488364470847 0.9357316317948484 0.3494113800101577 1.0 0.7027224406007859 2 Q92542 1 +Cell projection membrane 0.3859989041836575 0.9310356460490194 0.3518351255016705 1.0 0.703627789378457 62 Q9BZG1,P40855,P55011,P06756,O75787,P98164,Q15691,Q06481,P05556,Q04656,P51790,P00533,O00592,P31751,Q9H4M9,P20020 16 +Photoreceptor outer segment 0.5967343872228146 0.926195680002179 0.3543442971893182 1.0 0.703627789378457 5 P35613 1 +Myelin sheath abaxonal region 0.6373837995708368 0.9234580924283516 0.3557685300174251 1.0 0.703627789378457 4 Q96A65,P05556 2 +Ciliary basal body 0.4399733879520339 0.9082423641269616 0.3637501861179237 1.0 0.7063338743367442 16 Q9UPT5,Q8WWQ0,Q15154,P41208,A0AVF1,Q15691,O75419 7 +Insulin responsive compartment 0.7244336517425565 0.8907489143166888 0.3730638869599734 1.0 0.7121410215062203 3 P14672 1 +Sorting endosome 0.6270681304493884 0.8806814461354269 0.3784902618333363 1.0 0.717092370802609 4 P01130 1 +Beta catenin destruction complex 0.5839895013123348 0.8690758550077865 0.3848056421603649 1.0 0.7238202162557177 5 P35222,P25054,Q9HB71,P48729 4 +Copii vesicle coat 0.4727131788690999 0.856676565403604 0.3916236581225549 1.0 0.727531785501901 10 Q9Y6B6,Q9NR31 2 +Mitochondrial envelope 0.4362608118238663 0.8452718636909231 0.3979590666358552 1.0 0.7354179599769453 274 Q9NS69,Q8N4H5,O96008,P14406,O60830,O43169,Q15070,Q9Y512,Q96CU9,Q5T9A4,Q6UXV4,Q13505,Q9NQZ5,Q99595,O00584,O14949,Q86Y39,O43676,Q9Y2R0,Q14596,Q9H2D1,Q9BSK2,P12235,P12236,Q9UBX3,Q9H061,P09601,P45880,Q96A26,Q7KZN9,P21796,Q8WY22,O14925,Q9Y619,Q9UDW1,O75438,Q9NZ45,Q13423,Q9H3K2,Q8NBN7,Q9Y277,O95202,Q5XKP0,Q567V2,P52789,O75964,P39210,Q9UDX5,Q70HW3,Q9BUR5,Q9Y6M9,P53701,Q9UG56,Q9HC21,O95831,P0DP25,P03886,Q6P4A7,Q9BXK5,Q6NUK1,O00264,P23786,Q6DKK2,Q9NZJ7,O60313,P13073,P05141,Q9Y6C9,Q9P0J0,Q15526,O14786,Q16891,Q9NVI7,Q8IYU8,Q9NVH1,Q9BPX6,P03915,Q9P0S9,Q9NR28,O96000,P00403,Q7Z7H8,Q8IWA4,O95169,Q3ZCQ8,P22695,Q9BWH2,P57105 88 +Collagen containing extracellular matrix 0.4093135530001524 0.8431695783870328 0.3991336097988083 1.0 0.7354179599769453 34 Q08380,P53634,Q5SZK8,P14543,P07602,Q08431,P07942,P07858,Q9NZJ7 9 +Mitochondrial protein containing complex 0.3610232079591763 0.8368317012919495 0.40268717537286 1.0 0.7399545093366666 143 Q567V2,Q9NS69,Q8N4H5,O75964,O96008,P14406,O60830,P05141,Q9BUR5,Q9Y6M9,Q96CU9,Q9Y512,Q9P0J0,Q13505,P21796,Q99595,Q16891,O14925,Q8IYU8,Q9UDW1,Q9NVH1,Q9BPX6,P03886,O75438,P03915,O14949,O96000,P00403,Q86Y39,Q7Z7H8,Q8IWA4,O43676,O95169,P12235,P12236,Q3ZCQ8,P09622,P22695,Q5XKP0,P13073 40 +Tight junction 0.4049762380576699 0.8343930895244764 0.4040595100928301 1.0 0.7399545093366666 24 Q9Y624,Q86UE4,Q92796,Q9BTW9,Q16625,P78310,Q8WUM4,O43815 8 +Hrd1p ubiquitin ligase erad l complex 0.7013047638910351 0.8023406141453494 0.4223559549730733 1.0 0.7520607024322906 3 Q9BUN8 1 +Er ubiquitin ligase complex 0.7013047638910351 0.8023406141453494 0.4223559549730733 1.0 0.7520607024322906 3 Q9BUN8 1 +Somatodendritic compartment 0.3548413735725233 0.7918123203196914 0.4284701174578469 1.0 0.7554825358699023 139 P20339,Q96QD8,P55011,P05556,P04114,Q9BTU6,Q13277,P05067,Q15375,P17612,P27824,P42345,P08069,Q14254,Q16637,P50897,Q92673,P01130,P19021,Q13641,P20020,Q9UQB8,P04350,P98164,O75787,P08195,Q04656,Q7L0J3,O00264,P21964,P10586,O76024,O60313,Q96J84 34 +Guanyl nucleotide exchange factor complex 0.6012741148116575 0.7748327596643526 0.4384384887625261 1.0 0.7616632350935906 4 Q6IAA8 1 +Camp dependent protein kinase complex 0.6930470702672666 0.7711986418840311 0.4405891990829707 1.0 0.761940246398765 3 P10644 1 +Centriolar satellite 0.3966112275754495 0.7551325086544484 0.4501694792734456 1.0 0.7711077962459592 27 Q9UPT5,Q9Y5K6,Q03518,P53350,Q14145,O75955,O00592,O60271,Q15154,Q14498,Q13045,Q86UY6 12 +Apical junction complex 0.3970266071583515 0.7510653745232985 0.4526133128587284 1.0 0.7726464534883964 29 Q9Y624,Q86UE4,Q92796,Q16625,Q9BTW9,P78310,Q8WUM4,O60716,Q92692,Q16513,O43815 11 +Cilium 0.3315885767555316 0.7463280223028397 0.4554692877122936 1.0 0.7742977891108992 76 Q13501,Q9UPT5,P05023,Q15154,A0AVF1,P05067,P17612,A6NIH7,Q8WWQ0,Q15388,Q9Y5Y2,O75419,P10644,Q9BZG1,P04350,Q9NUQ9,P48729,Q92973,Q15691,P54709,P35613,O75386,P09622,Q15555,P41208,Q9H4M9 26 +Cell body 0.3201711012120232 0.714254980941759 0.4750695245629877 1.0 0.7962839548248799 101 Q15375,Q96QD8,O75787,P55011,P10586,P08195,P27824,Q04656,Q7L0J3,P04114,P05067,Q16637,Q9BTU6,P50897,Q92673,O00264,P19021 17 +Anaphase promoting complex 0.4600033934501608 0.690412012776058 0.4899351244622494 1.0 0.8084460860348005 9 P30260,Q9UJX4,Q9UJX3,Q96DE5,Q12834 5 +Mitochondrial crista 0.670619286302385 0.6879778728197037 0.4914667156341341 1.0 0.8084460860348005 3 O60313 1 +Ciliary plasm 0.427532215075132 0.6861718071300359 0.4926047738436243 1.0 0.8084460860348005 13 P10644,P17612,P04350,O75386,Q15555 5 +Cell leading edge 0.3230665682490741 0.6336929500774579 0.5262812267118191 1.0 0.8194955547683269 112 P20339,Q16625,P05556,O00592,Q13277,P07237,P05067,P19022,Q14254,O15511,P20020,Q9BZG1,P06756,O75787,Q06481,Q04656,P00533,P51809,O75955,P51790,P31751 21 +Motile cilium 0.3768153936591643 0.6126979561530963 0.5400760742057493 1.0 0.8337551560592199 25 P09622,Q13501,P41208 3 +Growth cone membrane 0.7145198295640729 0.6093930432338895 0.5422639479640428 1.0 0.8342704157720926 2 Q9UPT5 1 +Ion channel complex 0.3700882404088439 0.6083704427310939 0.5429418103561168 1.0 0.8342704157720926 19 P62942,P51798,Q8IYU8,Q9C0H2,Q4KMQ2,P0DP25,Q9BPX6,Q9H813 8 +Proton transporting v type atpase v1 domain 0.4871189148508973 0.5961269611849255 0.5510904141098485 1.0 0.8401564519678062 6 Q15904 1 +Endoplasmic reticulum plasma membrane contact site 0.7082923631596152 0.5875367676119387 0.5568432644437347 1.0 0.8456361172869071 2 Q9NTJ5 1 +Flotillin complex 0.4668339322352903 0.5608122256102436 0.5749255514874867 1.0 0.8519867136352393 7 O75955 1 +Plasma membrane signaling receptor complex 0.394281479311991 0.5573678429214006 0.5772761316427859 1.0 0.8540653441874385 15 P36896,O00560,P02786 3 +Intrinsic component of synaptic membrane 0.4146710254079354 0.552133039006075 0.580857207300062 1.0 0.8575664564373361 11 Q15375,P19022,P27824,Q92542,P51790,O14786,P20020 7 +Actin based cell projection 0.3698466604767207 0.5459890248883151 0.5850734814445491 1.0 0.8604944362622212 46 Q8IX05,P06756,Q04656,O00592,P05067,P36543 6 +Dendritic tree 0.3101954001563323 0.5312184926036017 0.5952673796254433 1.0 0.8664554265630442 105 P20339,Q96QD8,P05556,Q9BTU6,Q13277,P05067,Q15375,P17612,P27824,P42345,Q14254,P50897,Q13641,P20020,Q9UQB8,P98164,O75787,Q04656,Q7L0J3,P21964,O76024,O60313,Q96J84 23 +Cytoplasmic side of endosome membrane 0.6833824975418092 0.5030522625065484 0.6149275283320392 1.0 0.879415733421578 2 P20339 1 +Cell trailing edge 0.4656963915588016 0.4977368430777782 0.618669536211393 1.0 0.8806022940386494 6 O75955 1 +Extrinsic component of cytoplasmic side of plasma membrane 0.3512086644872308 0.470907997545134 0.6377064366211842 1.0 0.8948588465170936 19 Q9H0H5,P04899,Q96A49,P08754 4 +Ruffle membrane 0.3608623581045526 0.4640804709113414 0.6425900928929629 1.0 0.8948588465170936 30 Q06481,P06756,P51790,P31751 4 +Cytoplasmic side of membrane 0.3612157372358445 0.4539521604344696 0.6498632597643086 1.0 0.9008104569963724 42 Q9H0H5,P20339,Q9NR28,P62942,P08754,Q8TCT9,P04899,Q96A49,P17900,Q8TCT8,P20020 11 +Ciliary tip 0.5128235775491645 0.433838170240477 0.6644059613045898 1.0 0.9125453828284076 4 Q15555 1 +Cleavage furrow 0.3450794418010157 0.4270782600994608 0.6693223268923609 1.0 0.9160963712406948 19 Q9H0H5,P05556,O75935,P11233,O95630 5 +Immunological synapse 0.3754068694948276 0.4055197666208156 0.6850954917885075 1.0 0.9254957987709074 14 P10644,O15400,Q96L92,P20020 4 +Postsynaptic endocytic zone 0.6512618813503703 0.4020957865995969 0.687613533502075 1.0 0.9260684509497302 2 P09497 1 +Neuron spine 0.3510627051215247 0.3890303363551206 0.697253705398178 1.0 0.9347828688695128 30 Q7L576,O75787,P17612,Q9UQB8,P27824,P05556,P18085,P05067,P20020,O43815 10 +Wnt signalosome 0.6433956079973713 0.3789254820924784 0.7047432008413745 1.0 0.9366421064822944 2 P35222 1 +Oxidoreductase complex 0.3405019538542154 0.3639584569393072 0.7158890314451756 1.0 0.9429949452727348 56 O14949,P13674,P09622,O43169,O96000,Q9Y6M9,P22695,Q9P0J0,Q86Y39,Q9UDW1,O43676,P07237,P03886,O75438,O95169,P03915 16 +Nuclear pore central transport channel 0.4909806493932401 0.3580894237195112 0.7202763936334504 1.0 0.9429949452727348 4 Q8NFH5,Q7Z3B4,P61970 3 +Synaptic membrane 0.3484533426799071 0.3467403046907092 0.7287864277466298 1.0 0.9477977649873408 42 Q15375,P19022,O75787,Q9UQB8,P27824,Q99720,P05556,Q92542,P51790,Q9BTU6,P57105,Q13277,O14786,P20020 14 +Caspase complex 0.4192900100384428 0.3411612522784445 0.732982191466919 1.0 0.9477977649873408 7 Q9H490,Q92643 2 +Dendrite cytoplasm 0.377400037062423 0.3332587010959386 0.738939010973428 1.0 0.9521605339280246 10 Q14254,P27824 2 +T tubule 0.4153342022459639 0.3238419591410542 0.7460576877046383 1.0 0.9548266713378964 7 P05023,P14672 2 +Ccr4 not core complex 0.6227466404457481 0.3213172410518245 0.7479699921273704 1.0 0.9559162594422136 2 A5YKK6 1 +Neuron projection membrane 0.4138540512473125 0.3174079033959031 0.7509341109980023 1.0 0.9569895813425744 7 O75787 1 +Endoplasmic reticulum quality control compartment 0.4496905264901197 0.3096853203192787 0.7568002670401146 1.0 0.961744768128552 5 Q9BUN8 1 +Sarcoplasmic reticulum membrane 0.3982831730682614 0.3061039369349352 0.7595255104760132 1.0 0.9624929464681968 8 P16615 1 +Apicolateral plasma membrane 0.4169735746207285 0.2878365536643448 0.7734718551158388 1.0 0.971304138479378 6 Q16625 1 +Myofilament 0.5452459016393468 0.2824342878532778 0.7776105267967088 1.0 0.9730931731164372 3 P28289,Q9NYL9 2 +Striated muscle thin filament 0.5452459016393468 0.2824342878532778 0.7776105267967088 1.0 0.9730931731164372 3 P28289,Q9NYL9 2 +Outer kinetochore 0.5370491803278653 0.260951374509147 0.7941300058102514 1.0 0.9774742284631646 3 P53350,P14635 2 +Rough endoplasmic reticulum 0.333057687352241 0.2356897149748494 0.8136734513550088 1.0 0.992289388002096 34 Q9Y5M8,Q9UQB8,P51571,P04843,P27824,Q8TCT9,P05067,Q99442,Q9H9S5,Q07065,Q96A33 11 +Epsilon dna polymerase complex 0.4447359790095117 0.214544739538655 0.8301222819829741 1.0 0.9999200214794915 4 Q9NR33,Q07864,Q9NRF9 3 +Dynactin complex 0.4205770281849657 0.2088555082181289 0.8345610374365005 1.0 0.9999306854331788 5 Q13561 1 +Cell cell contact zone 0.3185302938770338 0.2051078653520345 0.8374878514125121 1.0 0.9999306854331788 23 P19022,P05556,O75955,Q14254,Q14126,P11166,Q92692 7 +Nuclear outer membrane 0.3510707608112786 0.2031532010529312 0.8390152901764407 1.0 0.9999306854331788 10 Q99720,P50402 2 +Protein kinase complex 0.3252816137914148 0.1989025869097748 0.8423389458865513 1.0 0.9999306854331788 30 P10644,O95067,P12956,P08069,P36896,P46020 6 +Proton transporting atp synthase complex coupling factor f o 0.3893043965487384 0.1810136379486873 0.8563568713113499 1.0 1.0 6 O75964 1 +Extrinsic component of postsynaptic specialization membrane 0.558833169452629 0.1759100717177032 0.8603645926543941 1.0 1.0 2 P52292 1 +Lamellipodium 0.3118964182013302 0.1622137448974639 0.8711375362880376 1.0 1.0 62 P51809,P06756,P19022,P05556,O75955,Q14254,O15511,O00592,Q13277,P07237,P05067 11 +Tertiary granule 0.3253722738922959 0.159772818139739 0.8730600369623005 1.0 1.0 42 O75787,Q93050,O15400,Q08722,Q92820,Q9H8H3,Q4KMQ2,Q8WVQ1,P11279,P10253,Q13510 11 +Cytoplasmic side of endoplasmic reticulum membrane 0.3732941497405914 0.1526537697481716 0.8786713197494422 1.0 1.0 7 Q8TCT8 1 +Presynaptic endocytic zone 0.4819672131147461 0.1379068901762932 0.8903140048703075 1.0 1.0 3 P09496,P09497 2 +Nuclear envelope 0.32681168181371 0.1343148454605917 0.8931536146311696 1.0 1.0 169 O14657,O94901,O75844,P80303,Q5SNT2,Q15154,O15173,Q9BW91,P05067,Q96P70,Q86UE4,O15118,O14681,Q99543,Q99720,O00560,Q92673,Q9BTX1,Q99735,Q9NQC3,P42167,P57088,Q99523,P00533,Q9H1E5,Q96KC8,Q6ZRP7,P50402,Q6NUM9,Q14739,Q9P035,Q8NFH4,P11717,Q96AG4,P41208,Q8NFQ8 36 +Escrt complex 0.3458823109654899 0.1293063214294942 0.8971152696518088 1.0 1.0 9 O43633,Q9H9H4,Q99816,Q9Y3E7 4 +Core mediator complex 0.3904199475065636 0.1171933596074437 0.906706828925244 1.0 1.0 5 O75448,Q9NPJ6,Q9NVC6,Q9Y2X0 4 +Flemming body 0.2957252081778394 0.0990094585900278 0.9211307601386438 1.0 1.0 19 Q9H0H5,Q9UPT5,Q8WUM4,Q96A65,Q99816,P11233 6 +Juxtaparanode region of axon 0.4540983606557317 0.0906704670443248 0.9277544378285568 1.0 1.0 3 Q15334,Q14168 2 +Rna polymerase ii transcription repressor complex 0.4945919370698054 0.08323648625708 0.9336635015492614 1.0 1.0 2 P35222 1 +Proximal dendrite 0.4936086529006765 0.0822160269016922 0.9344749289669698 1.0 1.0 2 P49840 1 +Distal axon 0.3104021875023781 0.0760278697674656 0.9393969254931966 1.0 1.0 55 P20339,Q99720,P51790,O15511,Q96A49,Q13561,P0DP25,P07196,Q13277,P05067,Q13641,P61421 12 +Neurofibrillary tangle 0.4818092428711783 0.0708225355414995 0.943538996089152 1.0 1.0 2 P07197 1 +Sin3 complex 0.3830764184978686 0.0682749769821555 0.9455667431131528 1.0 1.0 4 Q96ST3,Q13547,Q9UBU8 3 +Protein phosphatase type 2a complex 0.3614752699394895 0.0434625938768609 0.9653327820954788 1.0 1.0 5 Q15257 1 +Leading edge membrane 0.3095589328490827 0.0411600300258686 0.9671683180702536 1.0 1.0 41 P06756,O75787,Q06481,P05556,P51790,P00533,P31751,P20020 8 +Pml body 0.2941732155760966 0.0315378279715025 0.9748406247802252 1.0 1.0 25 Q13501 1 +Escrt i complex 0.4023365338246168 0.0292832755059251 0.9766386653956716 1.0 1.0 3 Q9H9H4 1 +Cul4 ring e3 ubiquitin ligase complex 0.3411962316240206 0.0255968145972578 0.9795789268221612 1.0 1.0 6 P61962 1 +Meiotic spindle 0.3898360655737705 0.0191235731718025 0.9847425261956324 1.0 1.0 3 P54652,Q9NQS7 2 +Transcription factor tfiih holo complex 0.387868852459011 0.0176719721379638 0.9859005401495932 1.0 1.0 3 P18074,Q96T76 2 +Crd mediated mrna stability complex 0.3350836888742965 0.0090831377503526 0.9927528042785224 1.0 1.0 6 O60506,Q00839,P67809,Q08211,Q9NZI8 5 +Hops complex 0.3701639344262238 0.0062775568722595 0.9949912671892074 1.0 1.0 3 Q96AX1,Q9P253 2 +Dendritic growth cone 0.3665573770491755 0.0043028344675975 0.9965668454044074 1.0 1.0 3 Q7L576,P08238 2 +Dendrite terminus 0.3665573770491755 0.0043028344675975 0.9965668454044074 1.0 1.0 3 Q7L576,P08238 2 +Anchored component of plasma membrane 0.3622950819672073 0.0021092834915446 0.9983170365156792 1.0 1.0 3 P36551,Q15334 2 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..073b5a1db9f0b17cc4a26e4553c30c6f4fa6639e --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Activin receptor complex", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc complex", "Blood microparticle", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Cbm complex", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Chylomicron", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Deuterosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Glycosylphosphatidylinositol n acetylglucosaminyltransferase gpi gnt complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner acrosomal membrane", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mks complex", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Phosphorylase kinase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Procentriole replication complex", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilium bundle", "Stereocilium membrane", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC2", "ASCC3", "ASF1B", "ASH2L", "ASNA1", "ASPH", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG7", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BIRC6", "BMS1", "BOLA2*", "BOP1", "BPHL", "BRCA1", "BRD2", "BRD4", "BRD8", "BRD9", "BRI3BP", "BRIX1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD31", "BYSL", "C14orf2", "C17orf75", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "CAB39", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CASP2", "CASP3", "CAST", "CBFB", "CBL", "CBX1", "CBX3", "CBX4", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC25", "CCDC47", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2AP", "CD2BP2", "CD302", "CD320", "CD3EAP", "CD46", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CDYL", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPI", "CENPM", "CENPV", "CEP170", "CEP290", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLIP1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLTA", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNOT1", "CNOT4", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPE", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT2", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTC", "CWC15", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DPF2", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC1", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM162A", "FAM208A", "FAM234B", "FAM3C", "FAM49B", "FAM83D", "FAM91A1", "FAM98A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FREM2", "FRG1", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLM2", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT2", "GPAA1", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSR", "GSTK1", "GSTM3", "GSTZ1", "GTF2E1", "GTF3C1", "GTF3C3", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HP1BP3", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INTS10", "INTS12", "INTS13", "INTS14", "INTS2", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ISCU", "ISOC1", "IST1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPK1", "IVD", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIRREL1", "KLC1", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMB1", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8E", "LRWD1", "LSG1", "LSM2", "LSM3", "LSM6", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYSMD3", "LZTS2", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED12", "MED16", "MED17", "MED24", "MED4", "MEPCE", "MESD", "METTL1", "METTL13", "METTL7A", "MFGE8", "MFN1", "MFSD8", "MGAT1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRC2", "MRE11", "MRFAP1", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL58", "MRPL9", "MRPS15", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTX1", "MTX2", "MUT", "MVB12A", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBN", "NBR1", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NENF", "NES", "NEU1", "NF1", "NFS1", "NHLRC2", "NHP2", "NID1", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NKRF", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NTHL1", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OXA1L", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PAM", "PARG", "PARK7", "PARN", "PARP1", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF14", "PHF5A", "PHF6", "PHIP", "PHKA1", "PHPT1", "PI4K2A", "PI4KB", "PICALM", "PIGA", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIN4", "PINX1", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL5", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT1", "RHOT2", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF219", "RNF40", "RNMT", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAGC", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCB", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERINC1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPOUT1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SRFBP1", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6", "TAF6L", "TAP1", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLK2", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM206", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM43", "TMEM59", "TMEM87A", "TMEM9", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM3", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TROVE2", "TRRAP", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPAN6", "TSR1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", 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0000000000000000000000000000000000000000..725a2af9833c846c2f08d0383e8e65c87ed6ea96 --- /dev/null +++ b/msigdb_gomf/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:990711d77fb353550319e2477149fe3486838b1d2efa660412e368b4c142d0cf +size 150173 diff --git a/msigdb_gomf/consensus.joblib b/msigdb_gomf/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d962ae1a38cdf04453d3005f6f8795e7f6f9d974 --- /dev/null +++ b/msigdb_gomf/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:717dce372a7415cf15af4375fa5e0cb6002df396b341a8763214fa7bd29df4d0 +size 158431 diff --git a/msigdb_gomf/df_merge.tsv b/msigdb_gomf/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..84af42a1bff9ac691ae1db826816e543856505f7 --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,85 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Ion transmembrane transporter activity 46 101 4.554337984653065 5.255080748112206e-06 37.34466019417476 101.497572815534 2.0154097423383375 0.2561362875319209 17.172953606300336 11.579295798802024 2.277787478419462 0.3756175790939143 2.2548917595111053e-15 0.4416690501766495 0.0777952445251919 1.2254485516389158e-07 1.306563128734923e-13 +Inorganic molecular entity transmembrane transporter activity 37 77 4.2311224809677 2.3252800457340683e-05 28.058252427184467 75.9635922330097 1.5031303400189615 0.2894264293069549 11.721339963426631 9.38477049228959 2.153051736566399 0.3821536813265525 1.031341013497967e-11 0.6941857055956011 0.6823587853277227 2.464607775054489e-05 1.1581291023128146e-10 +Transporter activity 83 175 3.8587309699073966 0.0001139773198646 62.22330097087379 172.27912621359224 2.173366592838491 0.2707201784543502 25.984753572620328 19.29276868436311 2.593156143256053 0.3916539604106395 5.95515364620819e-23 0.1022539316501712 0.0001188721116846 1.7686012276778093e-13 9.94269478446906e-22 +Cation transmembrane transporter activity 34 72 3.737308552482976 0.0001860006158544 25.62135922330097 70.51699029126213 1.766742880952279 0.2698419237572138 12.29126021871486 8.422243011776631 2.00238274385689 0.3706372466673562 2.0938762330580918e-10 0.6755398045514229 0.655123576832411 0.0001542585439863 1.54325944315088e-09 +Hydrolase activity hydrolyzing o glycosyl compounds 15 24 3.7150677713923415 0.0002031492399341 8.830097087378642 20.84223300970874 0.5983257656540719 0.2104301479001341 3.2223833352824554 2.4557961681485057 1.9540573665272416 0.2728112677124137 3.233838739632877e-10 0.0221752921752284 1.4997404178049758e-08 3.8477713450735775e-12 3.998615960432592e-10 +Molecular transducer activity 29 47 3.6914157994025216 0.0002230092245463 10.91747572815534 33.40533980582524 1.343848990749489 0.2329582295822712 4.7124072380860955 5.830391636254363 1.6098335072319665 0.2956883791113679 1.7414825047001674e-07 0.0076763500746692 0.0033327951560453 2.796101886343095e-07 2.6681961803426005e-06 +Active transmembrane transporter activity 34 73 3.602080723786034 0.0003156802976034 26.354368932038835 73.12621359223301 1.313035419122872 0.3239574057550545 11.878456281473593 8.663537710607383 1.88741562841277 0.3851687956916088 2.4218025298389673e-09 1.0 0.8606155698177973 0.0012599322682099 1.5142678953014604e-10 +Calcium ion binding 35 87 3.5349985459767947 0.0004077774022888 21.00485436893204 81.67961165048544 0.6464856503310022 0.4940276647939897 7.408010340962093 8.52860815905726 1.2261945166831902 0.3858741960292539 2.4949457921423957e-06 0.3860509975104039 0.0503965066473864 4.253583866897333e-05 5.6578800989406145e-08 +Steroid binding 11 20 3.4347457714236755 0.0005931099696998 8.424757281553399 21.398058252427184 1.4469817519716153 0.1523451695819165 3.035656818503787 2.066091501771892 1.85140774519605 0.2395996334984524 3.932880989186788e-07 1.0 0.3777229935777695 2.0229101637934145e-05 2.672510894072328e-06 +Hydrolase activity acting on glycosyl bonds 16 32 3.293862159281605 0.0009882094625619 10.133495145631068 28.40776699029126 0.6089784953463463 0.2409908190925149 3.36301188653944 3.2424277527979313 1.935823411407979 0.3010513017078077 2.48450009527639e-08 0.0479057539651017 4.387476342178553e-07 1.5805080749987167e-10 4.968296136325956e-08 +Anion transmembrane transporter activity 25 48 3.274704394998974 0.0010577259070569 18.594660194174757 45.61893203883495 1.6222323024349488 0.2373683627198559 9.346785472607134 6.017202751823004 1.8117646078257517 0.3183345645365742 4.320526335342405e-12 0.4570575797650001 0.0072395357132445 3.561701863714233e-07 2.4475618696375087e-10 +Metal ion transmembrane transporter activity 15 25 3.245640815634117 0.0011718659212947 9.563106796116504 24.67233009708738 0.8657396859235934 0.3700615753207195 4.93288923178502 4.839352380624028 1.4450904591933955 0.3424002804304004 0.0001168624926141 1.0 1.0 0.0758363007333116 0.0002620160776042 +Active ion transmembrane transporter activity 24 42 3.2281840993784634 0.0012457877076932 16.271844660194176 41.71116504854369 1.2957221273899948 0.3267733012969381 7.788084220174416 5.097264791179653 1.6571109350293016 0.3632481416270505 1.5454309145886532e-09 1.0 1.0 0.0022388598446307 1.653174009709179e-09 +Lipid transporter activity 8 20 3.1885210595757743 0.0014300259297193 6.546116504854369 19.805825242718445 0.7389006587243017 0.301332987440896 3.074370954053146 3.741159812966952 1.4134673193588587 0.2984913911167897 0.0037833067448725 1.0 0.0377829414296325 0.0005267369669417 0.0119325151844266 +Secondary active transmembrane transporter activity 13 25 3.158689395947852 0.0015848029602665 9.080097087378642 21.490291262135923 1.2627683473613005 0.2947710034053126 5.466215032972134 3.0675886156990426 1.4241587428281404 0.3340388164945335 1.0658052002576389e-05 1.0 1.0 0.0621642703962852 7.884368051330089e-05 +Exogenous protein binding 12 19 3.149164870688138 0.0016373779035299 4.509708737864078 15.157766990291265 0.7214109752050332 0.2527966464979699 2.499010078306418 1.9009100692398744 1.5211756979359785 0.2791170769282048 1.2325214263745618e-06 0.1952735388158895 0.3530974878629287 1.0512375529822254e-05 9.950941556486035e-07 +Gated channel activity 8 15 3.12241838577368 0.0017937183045075 4.317961165048544 13.019417475728156 0.8697524591818097 0.2583579989367679 2.2914716766946497 2.0107989163575497 1.3733766112751231 0.2762671399351702 0.000634598204816 0.2516504230112798 0.1132051672598368 0.0005812813538685 0.0022571444000092 +Cargo receptor activity 11 13 3.053047515038257 0.002265300666469 3.7063106796116503 7.95873786407767 0.9623237890522576 0.1578680760704802 1.9530058934839476 1.7914972745396005 1.6202205206532496 0.203966946010782 4.863777252803205e-09 0.0078974776787256 0.0023694947377154 5.193706499695607e-10 2.244530345295761e-09 +Peptide binding 19 69 3.026879070228865 0.0024709278898862 17.133495145631066 70.30339805825243 1.21997288878307 0.3503559587509399 5.621054768990946 6.443005397350486 1.219878183292811 0.3773673755377006 1.8276464888580293e-06 0.0333931709842731 0.0135319942444888 1.2580496545182384e-05 7.944966026214162e-06 +Antiporter activity 9 12 3.0208441354025557 0.0025207108044078 4.621359223300971 10.405339805825244 1.056576117278179 0.2813324268221227 2.679901841610502 1.304685592846984 1.2558310293487471 0.3063102364368053 2.3601455817660627e-06 1.0 1.0 0.0023536569339089 1.1813705775689822e-05 +Organic anion transmembrane transporter activity 19 28 2.9562889644430363 0.0031136522709971 12.951456310679612 30.182038834951456 1.56101282472555 0.2452312368187786 6.880574373146614 3.5222410835885483 1.575669523214114 0.314839840161206 7.034299690096876e-06 1.0 0.0483217377147592 0.0010205325993841 5.3235976749312936e-05 +Sterol binding 6 15 2.94961989766368 0.0031816509469566 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 0.0005119989488627 1.0 0.2941077913158182 0.0002012784147989 0.0014896299843671 +Amyloid beta binding 6 12 2.914945653663914 0.0035575048610529 3.5898058252427183 10.560679611650484 1.053866189591651 0.2544642672774957 2.009490338022764 1.9342863324228672 1.0942484681219342 0.2534200432416059 0.0006097953864012 0.1635258499471353 0.0052800410185589 0.0018532910789756 0.0017617577033715 +Snap receptor activity 8 13 2.9034494914737734 0.003690764983212 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 5.724009218244796e-06 0.151306852499084 0.2802926639431586 1.3832178397026686e-05 2.4597593044142757e-05 +Inorganic anion transmembrane transporter activity 12 22 2.899944072366285 0.0037322924768712 7.427184466019417 19.274271844660195 1.0921593405593897 0.2441056926448881 3.717191605498929 3.7816647851785734 1.4014196343960104 0.2816216967014333 9.841406294574505e-08 0.2220822570468345 0.0890100643743446 0.000237318493112 7.915219655591412e-07 +Nucleobase containing compound transmembrane transporter activity 10 14 2.839095760968071 0.0045241577534378 6.529126213592233 14.04126213592233 1.4296604886183193 0.212054291115069 3.2696940585469636 1.915888183904924 1.3255809572534116 0.2748813593420038 3.02291150747393e-05 1.0 0.0034893000144238 0.0009447024772989 0.000109129133689 +Cholesterol binding 6 12 2.8224725414374725 0.0047654902662201 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 0.0001540376426488 1.0 0.2518545844225215 6.929711507029932e-05 0.0004675519327548 +Voltage gated channel activity 6 11 2.7962182954163453 0.0051704464010671 3.2257281553398056 10.116504854368932 0.8578192560085278 0.2690365421745596 1.8168622808181427 1.411127559025233 1.234834479111217 0.2694186191218866 0.0003538454783329 1.0 1.0 0.0012549484261259 0.0010440793255692 +Sterol transporter activity 4 9 2.785972239279423 0.0053367441910372 2.621359223300971 8.364077669902912 0.5454888897585024 0.2973249899153176 1.425267849835305 1.6080715320593837 1.318674977748992 0.2709274408896192 0.0019559053195249 1.0 0.0202898922491691 0.0020705519968491 0.0042957165481444 +Anion channel activity 7 13 2.782389611744491 0.005396021839011 4.20873786407767 11.21116504854369 1.03959259790327 0.2192420598609839 2.3076742714116403 2.0905640066649145 1.3937691950814175 0.2662450395835827 1.030202474140748e-05 0.1263420182810564 0.0293903981750984 4.579056907329786e-05 3.828861199610836e-05 +Proteoglycan binding 6 7 2.7533638884353837 0.0058986292308658 1.362530413625304 3.1289537712895377 0.2680687531458016 0.4279813903596159 1.1106462996140136 1.3688980509063906 1.3416152040458127 0.3356932777486967 2.3250828389268664e-06 0.0786913117950012 0.1515272625734178 7.112875051220841e-08 7.746328029618005e-06 +Glycolipid binding 7 10 2.744503914746648 0.0060602431650687 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 2.3250828389268664e-06 0.0786913117950012 0.0113213926532688 3.906142953800441e-05 7.746328029618005e-06 +Protein transporter activity 9 16 2.740946195997126 0.0061262538446213 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 0.0003912809217482 0.0002227197090729 0.0016986126979642 2.2879176712764704e-05 0.0010205277760807 +Nucleotide transmembrane transporter activity 9 12 2.738736070528469 0.00616758637374 5.606796116504855 12.029126213592232 1.4217258291760082 0.2036087501116975 3.0234925518113496 1.8899648667798992 1.291115513359647 0.2666064512499804 8.662380537547521e-07 1.0 0.0010099703116007 0.0001186481206876 3.3887188864580013e-06 +Organophosphate ester transmembrane transporter activity 9 12 2.738736070528469 0.00616758637374 5.665048543689321 12.143203883495143 1.4298365636921646 0.2056324024803549 3.029697948284232 1.927415248708952 1.2819429632405106 0.2680490563295835 1.3133735168909995e-06 1.0 0.0011613234829685 0.0001505310959671 5.100313122590283e-06 +Growth factor binding 11 18 2.6926023777863337 0.0070896765253469 4.310679611650485 12.949029126213592 -0.0488380105863232 0.5194853451197696 2.1509949209095054 2.534197950354086 1.057563900891323 0.317878019437427 0.0004260933278178 0.0432831882721129 0.0285769937968429 0.0002471633761616 0.0017102987040416 +Alcohol binding 6 14 2.6879755971433177 0.007188664994763 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 0.0037651169531106 1.0 0.3837329617110586 0.0012377122057681 0.0025854516113679 +Voltage gated anion channel activity 5 7 2.672641952459373 0.0075256526697959 2.854368932038835 6.25 1.127126362633441 0.1649553590552043 1.5417035527207152 0.9966570336472054 1.4583344406160936 0.2334940994157564 7.792590264445566e-07 1.0 1.0 6.292953854873037e-05 2.2585304294532336e-06 +Tetrapyrrole binding 8 16 2.66769947877198 0.0076372537012694 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 0.0058138374452246 0.2295798469686227 0.4072036678679048 0.0096445533674611 0.001050513287845 +Serine hydrolase activity 7 17 2.610115452642781 0.0090511669945858 6.934466019417476 18.83009708737864 1.2767207242593377 0.1489147276149277 2.386872767465543 1.965791668457755 1.709796217367629 0.2208345231085202 0.0006145986943434 1.0 1.0 0.0009951056419778 0.0019780921583714 +Heparin binding 6 15 2.584990354968809 0.0097381721502654 3.4344660194174756 11.91504854368932 0.417671776261347 0.5410412518682232 1.977562601051691 1.5719219414069263 0.9122022863658426 0.3149614964035694 0.0017786180375354 0.1913705796369965 0.0666692325567911 0.0040251974639471 0.0048940429574069 +Carbohydrate derivative transmembrane transporter activity 7 10 2.541894030170329 0.0110253595061173 4.672330097087379 10.12135922330097 1.0096229459917263 0.2944050311743799 2.686158589641687 1.471354338494036 1.2935479322863277 0.3146313980204608 0.0034600956668483 1.0 0.2223047329091382 0.0242110622206542 0.0074494564855197 +Glycosaminoglycan binding 8 21 2.502058840973285 0.0123473401661167 4.978155339805825 17.45631067961165 0.1337124269810174 0.5629551361084434 2.38360266105164 2.069316753377374 0.9690169198659552 0.3148101721496325 0.004519526542567 0.2695684389372801 0.1290920553826253 0.0047615333276254 0.003940654279348 +Organic acid transmembrane transporter activity 5 18 2.482224493998229 0.0130564989255517 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.0566839588636807 1.0 0.1388614812827933 0.0824194625829831 0.1114390039799233 +Lipoprotein particle receptor activity 5 6 2.457760279708928 0.0139806460958473 0.558252427184466 1.9611650485436891 1.168446998823525 0.1996268153441312 0.915881905289026 1.1378085741458248 1.8266476741437696 0.265806683699643 1.655833142626512e-06 0.0516364610584135 0.0047533286028597 3.2862197875785204e-06 4.765057901286244e-06 +Sphingolipid binding 4 7 2.4486302869455416 0.0143400557041237 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 0.0005886601589281 0.083126337411673 0.1596960736798767 0.0007869115437374 0.0013369974246366 +Exopeptidase activity 12 31 2.4321085323644724 0.0150112085036775 9.74514563106796 31.84223300970874 1.193034763402526 0.2308543476384821 3.0338864063053523 1.9513159274241312 1.6646797512653713 0.2911825093455628 4.776658765296743e-06 0.2552681350600493 0.1163398228410075 1.936666177042337e-07 5.478593541938059e-06 +Monooxygenase activity 5 8 2.4270632195989776 0.0152216031444927 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 0.0222514049812011 1.0 0.2297987482657219 0.0267619345648551 0.0015706126808535 +Low density lipoprotein particle receptor activity 4 5 2.414318944472498 0.0157646558165691 0.9836734693877552 1.6448979591836734 -0.5593575058371455 0.2177029191255377 0.866460531450471 1.026398741884836 2.0898844560946817 0.275956017068443 2.2663533407456415e-05 0.0470522829573702 0.0039135152062846 1.828578586842436e-06 5.436360967141595e-05 +Sodium ion transmembrane transporter activity 5 6 2.4007014086982017 0.0163636828423245 3.033980582524272 6.733009708737864 0.6330876716410718 0.3951789521880264 1.773267150762252 1.4834287460359985 1.0827590126064015 0.3202441368223486 0.0050795814366564 1.0 1.0 0.6257540014635683 0.0119603409362114 +Protein transmembrane transporter activity 3 11 2.3925490726591065 0.0167317904499293 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 0.0041482574964162 6.765318543664244e-05 0.0005309775927247 0.00062382482254 0.0078812527225172 +Macromolecule transmembrane transporter activity 3 12 2.383612677760753 0.0171436352973199 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 0.0076717987785406 0.0001122733832082 0.0008717411361388 0.0011993766429203 0.0143001062154138 +Purine nucleotide transmembrane transporter activity 6 9 2.382519896999604 0.0171946027526734 4.334951456310679 9.441747572815531 0.9917737457277228 0.2833655940290197 2.4104227054611673 1.6217588601139772 1.262135146193827 0.3001583617421954 0.0003209345081955 1.0 0.1432798584585485 0.0062267265321947 0.0007388687073799 +Udp glycosyltransferase activity 7 16 2.3819977475857907 0.0172190027721996 5.111650485436893 16.645631067961165 0.3599735227181602 0.3819150449260511 2.50187506268716 3.5246228662547776 1.2344018614792536 0.2994506580113357 0.082829950054497 1.0 0.5166489093314391 0.0350926445127817 0.0709982362471757 +Hexosaminidase activity 3 5 2.358486769314308 0.0183496138858061 2.5194174757281553 4.973300970873787 0.3568105957806153 0.2227497456156347 1.091499214132507 0.3065083294438748 1.6445593916296413 0.2548912926080147 0.0002842581971033 1.0 0.0031504918831051 3.848915456526504e-05 0.0005688349419973 +Hexosyltransferase activity 14 35 2.346442211562219 0.0189536051065308 9.633495145631068 33.87864077669903 0.7349501031127185 0.3949358882560483 4.261380470236419 4.330948695045228 1.2646745007039175 0.3422146027467064 0.017105851352188 1.0 0.6695171460893661 0.0584431730757671 0.0091850044185398 +Vitamin transmembrane transporter activity 4 7 2.3339267999330717 0.0195995551677619 2.7766990291262137 6.252427184466019 1.4438342367310928 0.182339474606115 1.52603324115363 1.3650879028699858 1.0282691527982806 0.2346378729908682 0.0007725705229972 1.0 0.1677870330809631 0.0102137155300364 0.0017429018144962 +Proton transmembrane transporter activity 17 36 2.2948994741164546 0.021738885963094 12.769417475728156 35.478155339805824 1.2352045534927034 0.2879171268332734 5.319202861157036 2.7149368379617917 1.7021108079122016 0.3308025072902738 1.2682634409901412e-06 1.0 1.0 0.002033856678576 2.0440750709764312e-06 +Phospholipid binding 23 88 2.2920253665442805 0.0219041794615408 18.890776699029125 88.4635922330097 0.777309720287493 0.452120200534915 6.970479526806733 10.51702894240924 1.1988133109990275 0.3785217149858343 0.0380033433311808 0.7716358223716289 0.558792881991245 0.0636016933799903 0.0980140802923759 +Serine type exopeptidase activity 4 7 2.2629813579191578 0.0236368384878251 3.783980582524272 6.997572815533981 1.020609253431403 0.1137432544246352 1.3363606860118669 0.0492066381861973 1.87035730934538 0.1990592265121372 1.1721396217376793e-05 1.0 1.0 3.848915456526504e-05 2.8311070051942505e-05 +Atpase coupled transmembrane transporter activity 9 19 2.255542490020529 0.0240992983839165 8.072815533980583 22.696601941747577 0.8561067713091313 0.3392846662603397 4.166386392056555 3.892074110340729 1.3163009809214623 0.3229730128136945 0.0085995143684978 1.0 1.0 0.0515621560092188 0.0065824357934952 +Passive transmembrane transporter activity 10 36 2.2263314474911646 0.025991988545988 10.728155339805824 34.00242718446602 0.8598494327527568 0.3171523987434088 5.464704354730218 4.259483301090722 1.5882390061019254 0.3339692919660049 0.0064016428527453 0.4243503559946278 0.2997470465879412 0.020682535454445 0.0223997067615021 +Lipid transfer activity 2 7 2.21778476840654 0.0265695111537351 1.966019417475728 6.618932038834951 0.4006158968389467 0.3501200832710581 1.370213887212628 1.5743486325272755 1.2182069511780798 0.2776659407244052 0.1290050643080269 1.0 0.2590666885683055 0.1724444479617574 0.1889957663081205 +Glutamate receptor binding 3 8 2.2139125682530785 0.0268347939915234 2.2936893203883497 7.946601941747573 0.3900848348942944 0.57584767506371 1.7330759961215054 1.3318587299338784 0.7276949643591468 0.2861931388127574 0.0711695975173982 0.1093006244161378 0.2070995190727305 0.4452488918515388 0.0269295467729808 +Oxidoreductase activity acting on a heme group of donors 4 7 2.212169116767165 0.0269549818848215 3.111650485436894 6.483009708737864 0.8850005512180296 0.2757097651603665 1.538237610319269 1.0226572421183926 1.2777814224392188 0.2966482201944345 0.0025369657709893 1.0 1.0 0.307957256786686 0.0005289198821125 +Fad binding 5 8 2.208647709556677 0.0271991541407272 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 0.2841520442022208 1.0 1.0 1.0 0.3621483333283614 +Solute anion antiporter activity 3 6 2.208215191257248 0.027229275923142 2.3737864077669903 5.444174757281553 0.825822657258252 0.3439291028288794 1.663745987721657 0.8585888447978746 1.0247623924866192 0.2999489358207081 0.0006977887477165 1.0 1.0 0.027832231049335 0.0013781701696679 +Ceramide binding 4 5 2.203693904126801 0.027545878156888 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 0.0001046031266164 0.0607401038440192 0.1180585699575878 0.0002022933287296 0.0002457979454447 +Mannose binding 3 7 2.196558184894554 0.0280520153766457 2.487864077669903 6.235436893203883 0.6101269701833572 0.2582145467051042 1.3337836904766196 0.6757998162537485 1.36750331402198 0.2531492078603038 0.0001631307300422 1.0 0.0743799864466655 2.1797401302891516e-05 0.0003286021100258 +Scavenger receptor activity 4 5 2.1940638235075065 0.0282308215615361 2.128640776699029 4.245145631067961 0.8895147156183107 0.1752904943890176 1.2029313295363038 0.9324780265795692 1.5451274177295422 0.2106852326062687 6.657801000522381e-05 1.0 1.0 0.000142755965642 0.0001575214550341 +Protein lipid complex binding 5 7 2.1890935088455894 0.0285900442384827 1.3810679611650485 4.075242718446602 0.904959910455646 0.2381476109936121 0.9668941495076666 1.0318560378441015 1.279214127988033 0.237092245379572 3.198666701588262e-06 0.0561990347849709 0.0056684159955205 5.522373670119844e-06 9.139729707100432e-06 +Amide binding 25 100 2.1716230789209887 0.0298841047714981 22.521844660194176 102.53398058252426 0.8716704131409604 0.4134472412494542 7.596116055031058 7.786365397071367 1.2519470693533183 0.3815633057547212 2.360925023096113e-07 0.0168795268332449 0.0143035008339637 5.679112212529196e-07 7.003810490024876e-07 +Ionotropic glutamate receptor binding 2 6 2.155643077108069 0.0311115461482718 1.5072815533980584 5.189320388349515 0.4352952890916908 0.5486234361141443 1.2157723137108922 0.7294648419243608 0.7662696198250318 0.294972539733417 0.0826221138440168 0.0561990347849709 0.1094892401774078 0.2550529546148332 0.018020673376298 +Primary active transmembrane transporter activity 20 49 2.13111218511338 0.0330799011016464 17.696601941747574 52.529126213592235 1.0080198242353189 0.3544097082146772 7.649017203625277 6.455721193615876 1.66885648871365 0.3767837436492733 2.54724436067405e-05 1.0 0.6883336871670287 0.0086623262039441 2.6596484244335136e-07 +Calcium ion transmembrane transporter activity 5 13 2.129128429385784 0.0332436362420549 4.682038834951456 13.276699029126211 0.2388683150344522 0.4966462427664995 2.540615268048159 1.6898155172183935 1.0404105676043174 0.3190267550516111 0.0404851232425755 1.0 1.0 0.1048323445251165 0.0252009464097718 +Transition metal ion transmembrane transporter activity 4 5 2.1249822999486008 0.0335880898518403 2.2597087378640777 4.444174757281553 1.267846808399692 0.205487024774009 1.5353529408674886 1.9618423203326616 1.2931295194130703 0.2516620757205828 0.0023896230640102 1.0 1.0 0.0195244436529747 0.0052134507581354 +Transmembrane receptor protein kinase activity 5 7 2.105043403405139 0.0352875300862771 1.5266990291262137 3.405339805825242 -0.2400877987855226 0.4551118965545555 1.0891190778455828 1.2141042609169368 1.2003769712866084 0.3284266388044581 0.0437521233428844 0.0221752921752284 0.0775813155228076 0.1099245732268714 0.0818539267356338 +Sulfur compound transmembrane transporter activity 4 6 2.081396169717824 0.0373976589844766 2.9635922330097086 6.752427184466019 1.4746434057995097 0.1672652154050841 1.7026919602194592 1.5538455059459366 1.0954441166028872 0.2266277553273111 0.0282735799915187 1.0 0.2445730022705269 0.1552222190730896 0.0498364179528963 +Growth factor receptor binding 4 16 2.040369606682168 0.0413135267175075 5.233009708737864 16.303398058252426 0.6012049824390195 0.4932334837741021 2.455245557470486 2.477606131434232 0.8745174126419827 0.327387299755004 0.1824709554563119 0.2333020504203794 0.4129317333780675 0.1480244683995481 0.1272114080331624 +Serine type carboxypeptidase activity 3 5 1.9992451218437648 0.0455818386546318 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 1.2847188903596574e-05 1.0 1.0 0.0001354907423541 2.639864710894744e-05 +Peptide antigen binding 4 5 1.979649149221524 0.0477429661770791 2.25 5.218446601941747 1.3488418251083294 0.2076946662826 1.4985834735457568 1.269832767279765 0.9581301458127084 0.2397273125927817 0.0025369657709893 1.0 1.0 0.0051503840765812 0.0048822579474643 +Acetylglucosaminyltransferase activity 3 6 1.9702564349656115 0.0488089885926557 1.9951456310679612 5.055825242718447 -0.0810216128987761 0.3234962710075558 0.9926798720162284 1.0117225763032276 1.4217293374315634 0.2924894113397103 0.1025260209837266 1.0 0.2372212797486779 0.0294507732567689 0.0446088038944012 +Retromer complex binding 3 5 1.9670428593842328 0.049178269880947 1.7864077669902914 4.62378640776699 0.1266826261911074 0.4322045282144987 1.2199831722291083 0.628387698804986 1.1917576639553151 0.3183570223820515 0.0031730005700217 1.0 0.0743799864466655 0.0148625463558957 0.0053031795330487 +Extracellular matrix structural constituent 2 5 1.9656508344793464 0.0493389577287917 0.9710610932475884 1.9967845659163987 -0.2419122395269483 0.3832927981467602 0.7953634729766188 0.977227498494202 1.5943749197444836 0.3297256713914189 0.3190464947710471 1.0 1.0 0.7001645379952894 0.427430123643528 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..54c0297bbde66c8067b3fec4a849c27aa140049e --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 1386, + "title": "Average number of proteins per term", + "value": 16.085858585858585 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3a24100e67756de012a7d3b460ce38f96509aca5 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1170d086951c0b7e3ebd023945c686bebad209b7 --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,410 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ion transmembrane transporter activity 0.6458956756912515 4.554337984653065 5.255080748112206e-06 0.0072571002059767 0.0036417709584424 101 Q9HC07,Q96QD8,P55011,O75964,P45880,Q70HW3,Q8N4V1,P05141,P51798,P05023,Q7KZN9,Q9Y6M7,Q9C0H2,P04920,P21796,Q8IUH4,Q15526,Q8NEW0,Q93050,Q9HC21,Q9Y619,Q9UDW1,Q9HD20,Q6P4A7,P06756,Q8TB61,Q13423,P08195,P16615,Q04656,Q6NUK1,P30825,Q92581,Q9H813,Q9H2D1,P12235,P12236,Q9Y487,Q9UBX3,P51790,P11166,Q4KMQ2,Q9Y277,O95202,P13073,P36543 46 +Inorganic molecular entity transmembrane transporter activity 0.6460283077965556 4.2311224809677 2.3252800457340683e-05 0.0317149444090987 0.0107427938112918 77 Q9HC07,Q96QD8,P55011,O75964,P45880,P05023,Q8N4V1,P05141,P51798,Q9Y6M7,Q7KZN9,Q9C0H2,P04920,P21796,Q8IUH4,Q15526,Q15043,Q93050,Q9UDW1,Q9HD20,P20020,P06756,Q13423,P08195,P16615,Q04656,Q92581,Q9H813,P12235,Q9Y487,Q9UBX3,P51790,Q4KMQ2,Q9Y277,O95202,P13073,P36543 37 +Transporter activity 0.6344382540125756 3.8587309699073966 0.0001139773198646 0.1461344802919505 0.0351269754329481 175 Q9NS69,L0R6Q1,O60830,Q9C0H2,Q99595,Q8NEW0,Q14849,Q8TB61,P30825,Q7L0J3,O43676,Q9H2C2,P17900,Q9H813,Q9H2D1,Q9BSK2,P12235,P12236,Q9NV96,Q9UBX3,Q9HC07,P45880,Q7KZN9,P04114,O15173,P21796,O15118,Q93050,O14925,Q9Y619,Q9UDW1,Q9HD20,O75438,P06756,P98164,Q13423,P16615,Q04656,Q8NE01,Q92581,Q03518,P51790,P38435,P11166,Q4KMQ2,Q9Y277,O95202,Q96QD8,P61916,O75964,P39210,Q70HW3,Q8N4V1,P51798,Q9Y6M9,P04920,Q8IUH4,P04062,Q8NHS3,Q9HC21,P14672,P03886,Q6P4A7,P08195,Q6NUK1,Q8WTV0,Q9Y487,P13073,P36543,P55011,P05023,P05141,Q9Y6M7,Q9P0J0,Q15526,Q15043,P20020,P03915,O96000,P00403,O95169,Q8IXU6,O00400 83 +Cation transmembrane transporter activity 0.6283981133141441 3.737308552482976 0.0001860006158544 0.2272663309439782 0.0386363481526505 72 Q9HC07,Q96QD8,P55011,O75964,Q70HW3,P05141,Q8N4V1,P05023,Q9Y6M7,Q7KZN9,Q15526,Q8IUH4,Q15043,Q8NEW0,Q93050,Q9HC21,Q9Y619,Q9UDW1,Q9HD20,P20020,P06756,Q13423,P08195,P16615,Q04656,P30825,Q92581,P12235,Q9Y487,P51790,Q4KMQ2,O95202,P13073,P36543 34 +Hydrolase activity hydrolyzing o glycosyl compounds 0.8270341407555475 3.7150677713923415 0.0002031492399341 0.2454196033576729 0.0386363481526505 24 P54802,P04062,O00462,P16278,P06865,P04066,P06280,P07686,P08236,Q99519,Q9BTY2,O00754,P17900,P10253,Q9Y251 15 +Molecular transducer activity 0.7567124687264241 3.6914157994025216 0.0002230092245463 0.2659111843165209 0.0386363481526505 47 Q9UNN8,Q8IX05,Q9Y6I9,Q08722,O15173,P15260,Q9BUN8,P36896,Q15375,O15118,P98155,Q99720,Q92673,P20645,P06756,O75787,Q9UBG0,Q99523,P00533,Q14108,Q15629,O15031,P48960,P10586,Q8WTV0,P11717,Q07954,P15529,Q5KU26 29 +Active transmembrane transporter activity 0.6070977424357991 3.602080723786034 0.0003156802976034 0.3544173052350257 0.0486147658309278 73 Q96QD8,P55011,P05023,P05141,P51798,Q9Y6M7,Q7KZN9,Q9Y6M9,Q9P0J0,P04920,Q15526,Q15043,Q9UDW1,Q9HD20,P03886,O75438,P20020,P03915,P08195,P16615,Q04656,O96000,P00403,O43676,Q92581,O95169,P12235,P12236,Q03518,Q9UBX3,P51790,O95202,P13073,P36543 34 +Calcium ion binding 0.5345431607953923 3.5349985459767947 0.0004077774022888 0.4318073496514557 0.0565179479572294 87 Q9Y680,P80303,Q9BRK5,Q14126,Q96A33,O95302,P19022,P98155,P27824,Q8IYU8,P0DP25,Q9BPX6,Q14257,Q9UM22,P01130,P19021,P33908,O43852,O75071,P98164,Q02818,P16615,Q6NUK1,Q9NPF0,O94813,Q9NWM8,Q14574,Q9H223,P48960,Q07954,P41208,Q8WVQ1,Q9H4M9,O95202,P14543 35 +Steroid binding 0.7844980132054404 3.4347457714236755 0.0005931099696998 0.5605776684909343 0.074731856182182 20 P04062,P61916,O15118,P45880,P38435,Q14849,O15173,Q14108,P21796,O00264,O95772 11 +Hydrolase activity acting on glycosyl bonds 0.743208509116144 3.2938621592816055 0.0009882094625619 0.7459782830830713 0.1127698543985381 32 P54802,P04062,O00462,P16278,P06865,O75503,P04066,P06280,P07686,P08236,Q99519,Q9BTY2,O00754,P17900,P10253,Q9Y251 16 +Anion transmembrane transporter activity 0.6943535695479309 3.274704394998974 0.0010577259070569 0.7693338776311663 0.1127698543985381 48 Q96QD8,P55011,P45880,P05141,P51798,Q9Y6M7,P04920,Q9C0H2,P21796,Q9HC21,Q9Y619,Q8TB61,P08195,Q6NUK1,P30825,Q92581,Q9H813,Q9H2D1,P12235,P12236,Q9UBX3,P51790,P11166,Q4KMQ2,Q9Y277 25 +Metal ion transmembrane transporter activity 0.7474785425647983 3.2456408156341174 0.0011718659212947 0.8031195499491958 0.115110784190855 25 Q9HC07,Q96QD8,P06756,P55011,P08195,P05023,Q8N4V1,P16615,Q04656,Q9Y6M7,Q92581,Q8IUH4,Q15043,Q9HD20,O95202 15 +Active ion transmembrane transporter activity 0.7078904799534788 3.2281840993784634 0.0012457877076932 0.8223141514873492 0.115110784190855 42 Q96QD8,P55011,P05023,P05141,P51798,Q9Y6M7,Q7KZN9,P04920,Q15526,Q15043,Q9UDW1,Q9HD20,P20020,P08195,P16615,Q04656,P00403,Q92581,P12235,P12236,P51790,O95202,P13073,P36543 24 +Lipid transporter activity 0.7433026662545416 3.1885210595757743 0.0014300259297193 0.8624041423455419 0.1238759961619347 20 O15118,Q9NV96,P04114,Q14849,P11166,Q4KMQ2,Q9H2C2,P17900 8 +Secondary active transmembrane transporter activity 0.7335288442942894 3.158689395947852 0.0015848029602665 0.8890060166454558 0.1260780985718033 25 Q96QD8,P12235,P55011,P12236,P08195,P05141,P51798,Q9Y6M7,Q9UBX3,P51790,P04920,Q92581,O95202 13 +Exogenous protein binding 0.7374829570249272 3.149164870688138 0.0016373779035299 0.8968185037916846 0.1260780985718033 19 Q9Y624,P11279,P06756,O15118,P02786,P35613,Q8WTV0,P00533,P15529,Q14108,Q92692,P01130 12 +Gated channel activity 0.819409463523347 3.1224183857736794 0.0017937183045075 0.9169511189053382 0.1308470300025008 15 Q9H813,P06756,P45880,P51790,Q9C0H2,Q4KMQ2,P21796,Q9Y277 8 +Cargo receptor activity 0.8435910626171204 3.053047515038257 0.002265300666469 0.9568584320599562 0.151900224996056 13 Q08380,P98164,P02786,O15260,Q8WTV0,P98155,Q07954,Q14108,Q92673,Q5KU26,P01130 11 +Peptide binding 0.5693122559519896 3.0268790702288655 0.0024709278898862 0.9675788450601536 0.151900224996056 69 O43731,Q9UIQ6,Q9Y287,P40855,P24390,P10321,Q9NZ08,Q92673,Q9NQX7,P01130,P01889,Q92973,O00264,P42892,P04439,Q03518,P55786,Q07954,O14773 19 +Antiporter activity 0.8543489717740538 3.0208441354025553 0.0025207108044078 0.969745668018717 0.151900224996056 12 P12235,P12236,P08195,P51798,P51790,Q9UBX3,P04920,Q92581,O95202 9 +Organic anion transmembrane transporter activity 0.6980351466097601 2.9562889644430363 0.0031136522709971 0.9867300678521193 0.1763907284992772 28 Q96QD8,Q9H9B4,P05141,Q9Y6M7,O43808,Q9HC21,Q9Y619,Q99808,Q8TB61,P08195,Q6NUK1,P30825,Q9H2D1,P12235,Q15758,P12236,Q9UBX3,P11166,O00400 19 +Sterol binding 0.7870086238169932 2.94961989766368 0.0031816509469566 0.987927175961933 0.1763907284992772 15 O15118,P45880,Q14849,Q14108,P21796,O95772 6 +Amyloid beta binding 0.8328089066214175 2.914945653663914 0.0035575048610529 0.992841773981606 0.1847484776051261 12 Q07954,Q9Y287,Q92673,O00264,Q9NQX7,P01130 6 +Snap receptor activity 0.8139813902862456 2.9034494914737734 0.003690764983212 0.9940529705024672 0.1847484776051261 13 O95249,Q13190,Q9P2W9,O60499,O15400,Q86Y82,Q13277,Q9UNK0 8 +Inorganic anion transmembrane transporter activity 0.6953688603340122 2.899944072366285 0.0037322924768712 0.9943868036093708 0.1847484776051261 22 P55011,Q9Y277,P45880,P51798,Q9Y6M7,Q9UBX3,P51790,Q9C0H2,P04920,Q4KMQ2,P21796,Q9H813 12 +Nucleobase containing compound transmembrane transporter activity 0.7844414421327605 2.839095760968071 0.0045241577534378 0.9981354021883192 0.2084945052196024 14 P12235,L0R6Q1,Q8TB61,P12236,P05141,Q9HC21,Q6NUK1,O00400,Q9H2D1,Q9BSK2 10 +Cholesterol binding 0.8142332183633793 2.8224725414374725 0.0047654902662201 0.9986675789413442 0.2084945052196024 12 O15118,P45880,Q14849,Q14108,P21796,O95772 6 +Voltage gated channel activity 0.8240727212558339 2.7962182954163453 0.0051704464010671 0.999242001496584 0.2084945052196024 11 P06756,P45880,P51790,Q4KMQ2,P21796,Q9Y277 6 +Sterol transporter activity 0.8686038067966668 2.785972239279423 0.0053367441910372 0.9993987713062956 0.2084945052196024 9 Q14849,P04114,O15118,Q9H2C2 4 +Anion channel activity 0.790422563837393 2.782389611744491 0.005396021839011 0.9994464382606152 0.2084945052196024 13 Q9H813,P45880,P51790,Q9C0H2,Q4KMQ2,P21796,Q9Y277 7 +Proteoglycan binding 0.926460932370321 2.7533638884353833 0.0058986292308658 0.9997252660756244 0.2084945052196024 7 P07858,O00560,Q07954,O94813,P14543,Q9Y251 6 +Glycolipid binding 0.8274932753173779 2.7445039147466477 0.0060602431650687 0.9997806960348652 0.2084945052196024 10 O14773,P50897,P07602,Q92643,Q9H490,Q9UM22,Q9NZJ7 7 +Protein transporter activity 0.7307457467551126 2.740946195997126 0.0061262538446213 0.9997999820644295 0.2084945052196024 16 Q9NS69,P98164,O96008,O60830,Q07820,O14925,P08069,Q9HD20,Q99595 9 +Nucleotide transmembrane transporter activity 0.7975979996216999 2.738736070528469 0.00616758637374 0.9998111853513002 0.2084945052196024 12 P12235,Q8TB61,P12236,P05141,Q9HC21,Q6NUK1,O00400,Q9H2D1,Q9BSK2 9 +Organophosphate ester transmembrane transporter activity 0.7975979996216999 2.738736070528469 0.00616758637374 0.9998111853513002 0.2084945052196024 12 P12235,Q8TB61,P12236,P05141,Q9HC21,Q6NUK1,O00400,Q9H2D1,Q9BSK2 9 +Growth factor binding 0.6843660823117402 2.6926023777863337 0.0070896765253469 0.9999478449629706 0.2252177368076478 18 Q15375,P06756,P98164,Q9BZZ5,O00560,Q99523,Q92896,P11717,P00533,O14786,P36896 11 +Alcohol binding 0.7561756318571303 2.6879755971433177 0.007188664994763 0.9999545761988377 0.2252177368076478 14 O15118,P45880,Q14849,Q14108,P21796,O95772 6 +Voltage gated anion channel activity 0.9077730580894192 2.672641952459373 0.0075256526697959 0.9999716249692108 0.2252177368076478 7 P45880,P51790,Q4KMQ2,P21796,Q9Y277 5 +Tetrapyrrole binding 0.717984895799517 2.6676994787719797 0.0076372537012694 0.9999757200991968 0.2252177368076478 16 P30519,P09601,O43169,Q16850,Q7KZN9,P53701,O15173,O00264 8 +Serine hydrolase activity 0.6899410011443934 2.610115452642781 0.0090511669945858 0.9999966348413316 0.25089834908992 17 O75976,Q9H3G5,P53634,P10619,Q9HB40,O14773,Q16740 7 +Heparin binding 0.7208621574969793 2.584990354968809 0.0097381721502654 0.9999987130750786 0.2646491490248597 15 P10586,Q06481,P04114,O94813,Q13685,P05067 6 +Carbohydrate derivative transmembrane transporter activity 0.7857786370089603 2.541894030170329 0.0110253595061173 0.9999997878585786 0.2883235523675225 10 P12235,L0R6Q1,Q8TB61,P12236,P05141,Q6NUK1,O00400 7 +Glycosaminoglycan binding 0.6344577574699011 2.502058840973285 0.0123473401661167 0.9999999667743564 0.3002353240392591 21 P10586,Q06481,P04114,Q13685,O94813,P15586,O14786,P05067 8 +Organic acid transmembrane transporter activity 0.6506736069953538 2.482224493998229 0.0130564989255517 0.9999999877223242 0.3077837970721782 18 Q96QD8,Q9UBX3,P30825,Q9Y619,Q9H2D1 5 +Lipoprotein particle receptor activity 0.8841483426321016 2.457760279708928 0.0139806460958473 0.999999996648655 0.3196536660343472 6 P98164,P98155,Q07954,Q92673,P01130 5 +Sphingolipid binding 0.8568785669975245 2.4486302869455416 0.0143400557041237 0.999999997978045 0.3196536660343472 7 P21796,Q9UM22,P07602,P45880 4 +Exopeptidase activity 0.617217458286679 2.4321085323644724 0.0150112085036775 0.9999999992133785 0.3196536660343472 31 O75844,O75976,Q9H3G5,P02786,P16870,Q9UIQ6,P55786,P53634,P10619,Q92820,Q9HB40,O14773 12 +Monooxygenase activity 0.8220606642293182 2.4270632195989776 0.0152216031444927 0.9999999994149692 0.3196536660343472 8 P30519,P09601,Q16850,P19021,Q14534 5 +Low density lipoprotein particle receptor activity 0.937007874015746 2.414318944472498 0.0157646558165691 0.9999999997276334 0.3261166113696247 5 P98155,P01130,Q07954,Q92673 4 +Sodium ion transmembrane transporter activity 0.8710206760748297 2.4007014086982017 0.0163636828423245 0.9999999998828633 0.3269251759214897 6 Q96QD8,P55011,P08195,P05023,Q92581 5 +Protein transmembrane transporter activity 0.7435720806664305 2.3925490726591065 0.0167317904499293 0.9999999999302748 0.3269251759214897 11 Q9NS69,O60830,Q99595 3 +Macromolecule transmembrane transporter activity 0.7289525512132546 2.383612677760753 0.0171436352973199 0.9999999999609864 0.3269251759214897 12 Q9NS69,O60830,Q99595 3 +Purine nucleotide transmembrane transporter activity 0.7830045664665212 2.382519896999604 0.0171946027526734 0.9999999999636922 0.3269251759214897 9 P12235,Q8TB61,P12236,P05141,Q6NUK1,O00400 6 +Udp glycosyltransferase activity 0.6692805308535092 2.3819977475857907 0.0172190027721996 0.9999999999649204 0.3269251759214897 16 P06865,Q10471,P07686,P26572,Q10472,Q16739,O43505 7 +Hexosaminidase activity 0.923409555322116 2.358486769314308 0.0183496138858061 0.9999999999928848 0.3436833087260447 5 P54802,P06865,P17900 3 +Hexosyltransferase activity 0.6001735075201075 2.346442211562219 0.0189536051065308 0.999999999996968 0.3485698662698774 35 P04062,Q9BV10,P04843,P06865,Q9BT22,Q86SF2,Q10471,P07686,P26572,Q10472,Q2TAA5,Q16739,O43505,P46977 14 +Vitamin transmembrane transporter activity 0.8313522789553256 2.3339267999330713 0.0195995551677619 0.9999999999987832 0.3485698662698774 7 P04062,P11166,Q9H2D1,P38435 4 +Proton transmembrane transporter activity 0.59173731284016 2.2948994741164546 0.021738885963094 0.999999999999941 0.3638883923483492 36 P12235,Q13423,O75964,Q9Y487,Q93050,P05141,P51790,Q7KZN9,P00403,Q9UDW1,P56134,Q15526,Q92581,O95202,O00400,P13073,P36543 17 +Phospholipid binding 0.4283567768033673 2.2920253665442805 0.0219041794615408 0.9999999999999534 0.3638883923483492 88 Q9Y4P8,P45880,P04114,P07602,Q08431,P21796,Q9H4A5,Q8NCC3,O00560,P50897,Q9H490,Q9UM22,Q9H0H5,Q06481,Q14108,Q92643,Q9NZJ7,Q8WTV0,O75386,O43292,O14773,Q9BWH2,O60313 23 +Serine type exopeptidase activity 0.8157389464913245 2.2629813579191578 0.0236368384878251 0.999999999999996 0.3638883923483492 7 Q9HB40,O14773,O75976,P10619 4 +Atpase coupled transmembrane transporter activity 0.597679909084588 2.255542490020529 0.0240992983839165 0.999999999999998 0.3638883923483492 19 P05023,O14678,Q04656,P51798,P16615,Q03518,Q9HD20,P20020,P36543 9 +Passive transmembrane transporter activity 0.5825423265525268 2.2263314474911646 0.025991988545988 1.0 0.3638883923483492 36 P06756,Q9Y277,O75964,P45880,P39210,P51790,Q9C0H2,Q4KMQ2,P21796,Q9H813 10 +Lipid transfer activity 0.8058605198105646 2.21778476840654 0.0265695111537351 1.0 0.3638883923483492 7 Q14849,P04114 2 +Glutamate receptor binding 0.7766669066540388 2.2139125682530785 0.0268347939915234 1.0 0.3638883923483492 8 O75955,Q13501,P0DP25 3 +Oxidoreductase activity acting on a heme group of donors 0.8046367929608051 2.2121691167671655 0.0269549818848215 1.0 0.3638883923483492 7 Q15526,P16435,P13073,Q7KZN9 4 +Fad binding 0.7755603151677096 2.208647709556677 0.0271991541407272 1.0 0.3638883923483492 8 Q15392,Q15067,P00387,O95831,Q14534 5 +Solute anion antiporter activity 0.8273851960123155 2.208215191257248 0.027229275923142 1.0 0.3638883923483492 6 P04920,P12235,P12236 3 +Ceramide binding 0.8861548556430399 2.203693904126801 0.027545878156888 1.0 0.3638883923483492 5 P21796,Q9UM22,P07602,P45880 4 +Mannose binding 0.8012391812218981 2.196558184894554 0.0280520153766457 1.0 0.3638883923483492 7 O75503,O00462,P11717 3 +Scavenger receptor activity 0.8838582677165292 2.1940638235075065 0.0282308215615361 1.0 0.3638883923483492 5 Q07954,Q08380,Q5KU26,Q14108 4 +Protein lipid complex binding 0.7996167339506208 2.1890935088455894 0.0285900442384827 1.0 0.3638883923483492 7 P98155,Q92673,Q5KU26,P01130,Q9BQE5 5 +Amide binding 0.429215240596268 2.1716230789209887 0.0298841047714981 1.0 0.3638883923483492 100 O43731,Q9Y680,P45880,Q9UIQ6,Q9Y287,P07602,P21796,P24390,P10321,P40855,Q9NZ08,Q92673,Q9UM22,Q9NQX7,P01130,P01889,Q92973,O00264,Q9NZJ7,P42892,P04439,P55786,Q03518,Q07954,O14773 25 +Ionotropic glutamate receptor binding 0.8156366127691527 2.1556430771080692 0.0311115461482718 1.0 0.3638883923483492 6 O75955,Q13501 2 +Primary active transmembrane transporter activity 0.5451711625204244 2.1311121851133796 0.0330799011016464 1.0 0.3638883923483492 49 P05023,P51798,Q9Y6M9,Q7KZN9,Q9P0J0,Q15526,Q9UDW1,Q9HD20,P03886,O75438,P20020,P03915,P16615,Q04656,O96000,P00403,O43676,Q03518,P13073,P36543 20 +Calcium ion transmembrane transporter activity 0.6692034300984987 2.129128429385784 0.0332436362420549 1.0 0.3638883923483492 13 Q9HC07,P06756,P08195,P16615,O95202 5 +Transition metal ion transmembrane transporter activity 0.8674540682414623 2.1249822999486008 0.0335880898518403 1.0 0.3638883923483492 5 Q9HC07,Q8N4V1,Q04656,Q9HD20 4 +Transmembrane receptor protein kinase activity 0.7814449501566243 2.105043403405139 0.0352875300862771 1.0 0.3690982309239837 7 Q15375,P36896,P00533,P11717,O14786 5 +Beta n acetylhexosaminidase activity 0.9202438518440672 2.0959134767399252 0.0360898669909932 1.0 0.3690982309239837 4 P17900,P06865 2 +Sulfur compound transmembrane transporter activity 0.7991634442692309 2.081396169717824 0.0373976589844766 1.0 0.3690982309239837 6 Q70HW3,Q8TB61,Q9UBX3,Q9HC21 4 +Growth factor receptor binding 0.613169796532413 2.040369606682168 0.0413135267175075 1.0 0.4004234128004577 16 Q9NZ08,P05067,O00560,Q92542 4 +Sterol transfer activity 0.900148962933613 2.015465711852649 0.0438558752382143 1.0 0.4113501632019249 4 Q14849,P04114 2 +Serine type carboxypeptidase activity 0.8379041046482153 1.9992451218437648 0.0455818386546318 1.0 0.4118164058887908 5 Q9HB40,O75976,P10619 3 +Tap binding 0.8943916038045201 1.9923005301448091 0.0463380935769188 1.0 0.4118164058887908 4 P04439,Q03518,P10321 3 +Solute cation antiporter activity 0.8934076746474231 1.9883364979058331 0.046774486798377 1.0 0.4121575907332155 4 O95202,Q92581,P51790 3 +Peptide antigen binding 0.8333333333333242 1.979649149221524 0.0477429661770791 1.0 0.4121575907332155 5 P04439,Q03518,P01889,P10321 4 +Acetylglucosaminyltransferase activity 0.7747574550216899 1.9702564349656115 0.0488089885926557 1.0 0.4121575907332155 6 P06865,O43505,P07686 3 +Retromer complex binding 0.8303976955834732 1.9670428593842328 0.049178269880947 1.0 0.4121575907332155 5 P20645,Q99523,P11717 3 +Extracellular matrix structural constituent 0.830073761777692 1.9656508344793464 0.0493389577287917 1.0 0.4121575907332155 5 P14543,Q08431 2 +Protein carrier chaperone 0.696034992084382 1.9510985881317249 0.0510453191488537 1.0 0.413027278826671 9 Q15070,Q8N4V1 2 +Low density lipoprotein particle binding 0.8835683830764102 1.948614725383276 0.0513414522632302 1.0 0.413027278826671 4 Q5KU26,P01130,Q92673 3 +Transmembrane receptor protein tyrosine kinase activity 0.7685761498573596 1.9418942062791784 0.0521499089427615 1.0 0.413027278826671 6 Q15375,O14786,P00533,P11717 4 +Atp transmembrane transporter activity 0.8221784776902731 1.9316628644980705 0.0534011311406275 1.0 0.4152098650859754 5 P05141,P12235,Q6NUK1,P12236 4 +Metalloexopeptidase activity 0.5502429164726413 1.9275818149891708 0.0539071625884375 1.0 0.4152098650859754 20 O75844,O75976,P02786,P16870,Q9UIQ6,P55786 6 +Amino acid transmembrane transporter activity 0.6654126956267968 1.9269403127734075 0.0539870688108949 1.0 0.4152098650859754 10 Q96QD8,Q15758,P08195,P30825,Q9Y619 5 +L amino acid transmembrane transporter activity 0.6888769558689335 1.9146053115812345 0.0555428572400027 1.0 0.4152098650859754 9 Q96QD8,Q15758,P08195,P30825,Q9Y619 5 +Peptidase activity 0.4243622456397512 1.912276583439837 0.0558407276881867 1.0 0.4152098650859754 119 O75844,Q9H3G5,Q9UIQ6,Q96FW1,P10619,Q9HB40,Q16740,P07858,P02786,P49721,P53634,P60900,Q92820,Q9BXS4,Q9NZ08,P16870,Q99538,Q92542,Q15005,Q92643,Q9BT78,P67812,O75976,P42892,P55786,O14773,Q8TCT8 27 +Solute cation symporter activity 0.6836878899484374 1.8880574727643809 0.0590182352386581 1.0 0.4152098650859754 9 Q15043,Q96QD8,P55011,Q9Y6M7 4 +Symporter activity 0.6482366697888909 1.88712676551476 0.0591432774681683 1.0 0.4152098650859754 11 Q96QD8,Q15758,P55011,Q9Y6M7,Q9BXP2,Q15043,O00400 7 +Glycosphingolipid binding 0.8677295511010665 1.8843662458163923 0.0595154523121768 1.0 0.4152098650859754 4 Q9UM22,P07602 2 +Phospholipid transporter activity 0.7560122986383278 1.8839832493110715 0.0595672412871322 1.0 0.4152098650859754 6 Q9NV96 1 +Antigen binding 0.7341531773500503 1.8825042628212512 0.0597675816401095 1.0 0.4152098650859754 7 P04439,Q03518,P01889,P10321 4 +Clathrin heavy chain binding 0.7487177227828767 1.850199906310103 0.0642847424723349 1.0 0.4324040940111422 6 Q07954 1 +Membrane insertase activity 0.7478132091776011 1.8460027090004496 0.0648918120882522 1.0 0.4324040940111422 6 Q15070 1 +P type transmembrane transporter activity 0.8547064611347917 1.8312639640745856 0.0670611535696839 1.0 0.4405059661022838 4 P16615,Q04656,P05023 3 +Insulin like growth factor binding 0.7968734049090698 1.8219654482602852 0.0684602284522317 1.0 0.4422907699120412 5 P06756,P11717 2 +Coreceptor activity 0.7959317585301816 1.8178614211537856 0.0690853160565176 1.0 0.4427600290954616 5 P05556,Q92692,P06756,O14786 4 +Aspartic type peptidase activity 0.7905316881172055 1.794296212880302 0.0727659022601889 1.0 0.4500351861993165 5 Q8TCT8,Q92542 2 +Ephrin receptor binding 0.6651279670270109 1.7924703153473838 0.0730576600972916 1.0 0.4500351861993165 9 Q15375 1 +Oxidoreduction driven active transmembrane transporter activity 0.529553710270621 1.785577533248949 0.0741676872691816 1.0 0.4507172756629428 30 O96000,Q9Y6M9,Q7KZN9,Q9P0J0,P00403,Q9UDW1,O43676,Q15526,P03886,O75438,P13073,P03915 12 +Atpase coupled cation transmembrane transporter activity 0.6184224633680144 1.7777853857191068 0.0754391096217588 1.0 0.4507172756629428 12 P16615,Q04656,P05023,Q9HD20,P20020,P36543 6 +Atpase binding 0.5255582320447569 1.7554157762955858 0.0791882154845122 1.0 0.4507172756629428 30 P54709,P40855,Q9Y487,Q93050,P36543,Q92542,P00533,O76024,Q16740,Q9BUN8,P11233,Q8NFQ8 12 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.8358486841120019 1.7539474668979131 0.0794395090868211 1.0 0.4507172756629428 4 Q9UHG3,Q6ZRP7 2 +G protein alpha subunit binding 0.7776765779609135 1.7379972990073371 0.0822112897020184 1.0 0.4507172756629428 5 Q02818,P80303,P11717 3 +Endopeptidase activity 0.4478288838448945 1.7341548515672032 0.0828906112750802 1.0 0.4507172756629428 67 O75844,Q16740,P07858,P49721,P53634,P60900,Q9BXS4,Q9NZ08,Q99538,Q92542,Q92643,P67812,Q9UPU5,P42892,P22695,O43292,Q8TCT9,O14773,Q8TCT8 19 +Wide pore channel activity 0.8307641849786709 1.7330187466283995 0.0830923368292573 1.0 0.4507172756629428 4 P45880,Q9Y277,P21796 3 +Porin activity 0.8307641849786709 1.7330187466283995 0.0830923368292573 1.0 0.4507172756629428 4 P45880,Q9Y277,P21796 3 +Amide transmembrane transporter activity 0.8302585348863665 1.7309355424377704 0.0834632615221937 1.0 0.4507172756629428 4 Q03518,Q9H2D1 2 +Pdz domain binding 0.6192441062563713 1.727433570062427 0.0840898259921785 1.0 0.4507172756629428 11 Q9Y624,Q15067,P20020,P51790 4 +Snare binding 0.5209584813992385 1.7135067856801685 0.0866193460655448 1.0 0.4564806602541643 27 P49755,Q13190,P51809,O60499,O15400,Q5SQN1,Q86Y82,P54920,Q13277,Q9UNK0 10 +Er retention sequence binding 0.9885283513602112 1.7043961568165238 0.0883071014356775 1.0 0.4636122825373071 2 O43731 1 +Nedd8 specific protease activity 0.9279455462518648 1.6966867483959007 0.0897558993270712 1.0 0.4660567207078017 3 Q96FW1 1 +Adp transmembrane transporter activity 0.8219088225647632 1.6964883034424338 0.089793443409839 1.0 0.4660567207078017 4 P05141,P12235,P12236 3 +Phosphotransferase activity for other substituted phosphate groups 0.7140409341923581 1.688038164630451 0.0914039030586775 1.0 0.4692067023678778 6 Q9NRN7,P48651,O14735,Q9H9S5 4 +Integrin binding 0.5154343750940945 1.676897152151266 0.0935625951426308 1.0 0.4785157079988428 21 Q9Y624,P06756,Q08431,P07942,P07237 5 +Solute proton antiporter activity 0.918688524590164 1.6600675707150243 0.0969008599101219 1.0 0.4876053774019969 3 Q92581,P51790 2 +Carbohydrate binding 0.4918521312013534 1.6573922222825337 0.0974402028608969 1.0 0.4876053774019969 48 P52789,Q8IX05,O00462,P35613,P13674,Q9UBG0,O75503,P27824,Q10471,P11717,P08236,Q10472,P10253,O00754,Q5KU26,P19021 16 +Glucosidase activity 0.7591513609384504 1.656386481302205 0.0976435770140486 1.0 0.4876053774019969 5 P10253 1 +Galactoside binding 0.976728941330712 1.655601621589015 0.0978025215856819 1.0 0.4876053774019969 2 P06280 1 +Galactosidase activity 0.976728941330712 1.655601621589015 0.0978025215856819 1.0 0.4876053774019969 2 P06280 1 +Collagen binding 0.603869108958807 1.6416535879477523 0.1006618152516987 1.0 0.4956025039070997 11 Q9UBG0,Q92791,P05556,P14543,Q53GQ0,P07858 6 +Mannosidase activity 0.8074778615939517 1.6367480555000005 0.1016831234072617 1.0 0.4956025039070997 4 O00462,P33908,O00754 3 +Voltage gated chloride channel activity 0.912459016393442 1.6353888382205717 0.101967560774276 1.0 0.4956025039070997 3 Q4KMQ2,P51790 2 +Mannosyltransferase activity 0.6828601167688106 1.635133164867058 0.1020211351049076 1.0 0.4956025039070997 7 Q9BT22,Q9BV10 2 +Gamma catenin binding 0.7509079367264014 1.6198974125060304 0.1052543157799199 1.0 0.4963578338057683 5 P19022,Q14574 2 +Carboxypeptidase activity 0.578514993040721 1.6056290546345913 0.10835543769334 1.0 0.4963578338057683 13 Q9HB40,O75976,P10619,P16870 4 +Sulfatide binding 0.9632907243526738 1.5999698453167135 0.1096052731257741 1.0 0.4963578338057683 2 P50897 1 +Lysophosphatidic acid binding 0.9632907243526738 1.5999698453167135 0.1096052731257741 1.0 0.4963578338057683 2 P50897 1 +Lipoprotein particle receptor binding 0.5869928628634307 1.5978486570128243 0.1100766628886178 1.0 0.4963578338057683 12 Q07954 1 +Glycosyltransferase activity 0.4856591602653191 1.58764937701844 0.1123656461355855 1.0 0.497218577993342 47 P04062,Q9BV10,P06865,Q9BT22,Q68CQ7,Q10471,P07686,P26572,Q10472,Q2TAA5,Q16739,O43505,P46977,P43490 14 +Phospholipase d activity 0.9564077351688024 1.5714581268056862 0.1160762733970193 1.0 0.4986651225616475 2 Q8IV08 1 +Intramembrane lipid transporter activity 0.8960523723634819 1.57026887950231 0.1163525709923773 1.0 0.4986651225616475 3 Q9NV96 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.5015491817328159 1.5677869782918712 0.1169308548575291 1.0 0.4986651225616475 27 P30519,P13674,P09601,Q15800,Q8IUF8,Q16850,P16435,Q8NB78,P07237,P19021,Q9Y2K7,Q14534 12 +Peptidase activator activity 0.5902933247779345 1.5653072162922497 0.1175108919085412 1.0 0.4996015220406079 11 P53634,P05067,Q9BXK5 3 +Protein disulfide isomerase activity 0.6210436510051922 1.5616013455978175 0.1183819322960797 1.0 0.5001903875771799 9 Q6ZRP7,Q96JJ7,Q92643 3 +Cation cation antiporter activity 0.8931147540983583 1.5585921194310928 0.119092949423138 1.0 0.5001903875771799 3 O95202,Q92581 2 +Extracellular matrix binding 0.6662736813886587 1.553898090162374 0.1202087273706786 1.0 0.5033513478421772 7 P14543,P06756 2 +Potassium ion transmembrane transporter activity 0.7867521425844739 1.550530760362627 0.1210141763556225 1.0 0.5051977362316048 4 P55011,Q92581 2 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.9472304162569648 1.5334320070824283 0.1251694475248768 1.0 0.5132687996138439 2 P09601 1 +Ganglioside binding 0.885573770491799 1.5285967919067331 0.1263644318192907 1.0 0.5139690646125206 3 Q9UM22,P07602 2 +Neutral amino acid transmembrane transporter activity 0.7300661502646107 1.5271996982306897 0.1267113613384152 1.0 0.5139690646125206 5 P08195,Q96QD8,Q15758 3 +G protein beta gamma subunit complex binding 0.7288653679961602 1.5218407659796331 0.1280489841417187 1.0 0.5144228754215134 5 P04899,P41208,P08754 3 +Neurexin family protein binding 0.9439528023598864 1.5198498626018362 0.1285487138668823 1.0 0.514937911617049 2 P16870 1 +Gtp dependent protein binding 0.6575207111214719 1.510804041086148 0.130838384826162 1.0 0.5182836429460365 7 O00429,Q9BZG1,P61020 3 +L ornithine transmembrane transporter activity 0.94133071124222 1.5089840902982714 0.1313028485784579 1.0 0.5182836429460365 2 P30825 1 +Lipid binding 0.4046339821461225 1.5080962585673323 0.1315298926606178 1.0 0.5182836429460365 134 P61916,Q9Y4P8,P45880,P05023,Q96L92,P04114,P07602,O15173,P21796,Q9NQZ5,Q08431,Q13277,P04062,O15118,Q9H4A5,Q15067,Q8NCC3,O00560,A6NIH7,Q14849,P50897,Q9H490,Q9UM22,Q9H0H5,Q06481,Q14108,O14735,Q92643,O00264,Q9NZJ7,Q8WTV0,O75386,P11717,P38435,O14773,O43292,Q9BWH2,O60313,O95772,Q9BQE5 40 +Aspartic endopeptidase activity intramembrane cleaving 0.8803278688524538 1.5077145818042996 0.1316275918593108 1.0 0.5182836429460365 3 Q92542,Q8TCT8 2 +Glucosyltransferase activity 0.6317726690178878 1.4971605396111356 0.1343514902977631 1.0 0.5260202416742931 8 Q16739 1 +Phosphatidylserine binding 0.5760308044637314 1.4845157587002793 0.1376721456299476 1.0 0.5281645502840059 11 Q06481,Q14108,Q08431 3 +Apolipoprotein binding 0.7196966616709707 1.4808611325471412 0.1386435821108058 1.0 0.5281645502840059 5 P98155,Q07954,Q8WTV0 3 +G protein coupled receptor activity 0.8733872932067237 1.4800690581953466 0.1388548180058824 1.0 0.5281645502840059 3 P48960 1 +Palmitoyl protein hydrolase activity 0.6694457605392001 1.4759756163818254 0.1399504382051923 1.0 0.5281645502840059 6 Q9UMR5 1 +Syntaxin binding 0.5000415678566638 1.4749195772685415 0.1402341663091733 1.0 0.5281645502840059 18 P49755,O60499,O15400,Q5SQN1,P54920,Q9UNK0 6 +Protein tyrosine kinase activity 0.5119805876408745 1.4696918966689922 0.1416452183933352 1.0 0.5294000871317752 17 Q15375,O14786,P00533,P11717 4 +Solute sodium symporter activity 0.8701639344262315 1.4672239768036048 0.1423151365159576 1.0 0.5294000871317752 3 Q96QD8,P55011 2 +Laminin 1 binding 0.93117010816126 1.4668831578357315 0.1424078428703876 1.0 0.5294000871317752 2 P14543 1 +Palmitoyltransferase activity 0.7165218978331538 1.4666472875450205 0.1424720292208889 1.0 0.5294000871317752 5 P23786,Q8IUH4 2 +Manganese ion transmembrane transporter activity 0.8668852459016313 1.454155080800173 0.1459033154780891 1.0 0.5366626668989858 3 Q9HC07,Q9HD20 2 +Protein macromolecule adaptor activity 0.3622562965754871 1.4515608609125448 0.1466237481366246 1.0 0.5366626668989858 87 O95249,Q13190,O60499,Q9P2W9,O15400,O00560,Q92542,Q9NRX5,P61962,Q96D46,Q86Y82,Q9BTX1,Q13277,Q9UNK0 14 +Syndecan binding 0.9272369714847588 1.4505897411889328 0.1468941336278781 1.0 0.5366626668989858 2 O00560 1 +Acylglycerol o acyltransferase activity 0.7622535209970487 1.448069220288705 0.1475976926932931 1.0 0.5369301891677278 4 Q96N66,Q8NCC3 2 +Mhc class ib protein binding 0.9236315961979678 1.4356570342255817 0.1510999568863611 1.0 0.5417410670545094 2 Q9NUQ9 1 +O acyltransferase activity 0.6186790572443926 1.4298817256530645 0.1527509677582228 1.0 0.5456516528682909 8 P23786,Q96N66,P35610,Q8NCC3 4 +Hormone binding 0.5949706190685587 1.4227168952262943 0.1548182408510638 1.0 0.5502002097937808 9 P05023,P98164,P42892,P00533 4 +Metal ion proton antiporter activity 0.9183874139626352 1.4139431485459386 0.1573785955352025 1.0 0.554582842759544 2 Q92581 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.8501639344262308 1.3874660234930405 0.1652997046113093 1.0 0.5640932884429952 3 Q16850,Q14534 2 +Intracellular calcium activated chloride channel activity 0.849211697476546 1.383667043424167 0.1664604292735823 1.0 0.5640932884429952 3 Q9C0H2 1 +Ion gated channel activity 0.849211697476546 1.383667043424167 0.1664604292735823 1.0 0.5640932884429952 3 Q9C0H2 1 +Gtpase activity 0.361985838690055 1.3771944954455444 0.1684521232455478 1.0 0.568064824375497 81 P20339,Q14344,Q15286,Q9H089,Q969Q5,P62820,P51148,Q9NP72,Q8IXI1,Q9NR31,P51151,P40616,P61026,P61020,Q6DD88,Q9H0U4,Q5HYI8,P11234,Q9Y6B6,Q9BUF5,Q9BZG1,P04350,P36404,Q14964,P04899,P61019,Q8IWA4,Q9HB90,O00429,P08754,Q8NHH9,O60313,P51149,P18085,P11233 35 +Mhc protein binding 0.5855575510976302 1.372196944535813 0.1700021363515929 1.0 0.5702864438761761 9 Q9NUQ9,Q03518 2 +Nadh dehydrogenase activity 0.4735973679424959 1.36570204083031 0.17203250352621 1.0 0.5730988851445227 22 O96000,Q9Y6M9,O95831,Q9P0J0,O43676,P03886,O75438,P03915 8 +Vitamin d binding 0.9056047197640118 1.361059957777268 0.1734947424099704 1.0 0.5731709341738941 2 P38435 1 +Abc type transporter activity 0.643296533225559 1.3500588040519703 0.1769971212444621 1.0 0.5773693784995687 6 Q03518,Q9HD20 2 +Azole transmembrane transporter activity 0.9019993444772304 1.3461589512609942 0.1782512601409829 1.0 0.5773693784995687 2 P30825 1 +D glucose transmembrane transporter activity 0.9013438216978038 1.3434505066715507 0.1791261419587406 1.0 0.5773693784995687 2 P11166 1 +Sugar transmembrane transporter activity 0.9013438216978038 1.3434505066715507 0.1791261419587406 1.0 0.5773693784995687 2 P11166 1 +Carbohydrate transmembrane transporter activity 0.9013438216978038 1.3434505066715507 0.1791261419587406 1.0 0.5773693784995687 2 P11166 1 +Metalloendopeptidase activity 0.5252154487470333 1.341551417279176 0.1797414876038918 1.0 0.5778961472826032 14 P42892 1 +Gpi anchor binding 0.8383606557377015 1.3403749531892124 0.1801234744776945 1.0 0.5778961472826032 3 Q9H490,Q92643 2 +Mitochondrial ribosome binding 0.7348122019925523 1.332764807426864 0.1826089980944525 1.0 0.5804955765112643 4 Q15070 1 +Chloride channel inhibitor activity 0.8957718780727696 1.3204400128863742 0.186688151747858 1.0 0.5840852783804316 2 O15400 1 +Chloride channel regulator activity 0.8957718780727696 1.3204400128863742 0.186688151747858 1.0 0.5840852783804316 2 O15400 1 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.7309826053227687 1.316641735336546 0.1879587422574287 1.0 0.5841049703336237 4 P04843,P46977 2 +Oligosaccharyl transferase activity 0.7309826053227687 1.316641735336546 0.1879587422574287 1.0 0.5841049703336237 4 P04843,P46977 2 +Metallopeptidase activity 0.4618005499875171 1.3120907260864434 0.1894895246962165 1.0 0.5863081698489431 41 O75844,O75976,P02786,P16870,P42892,Q9UIQ6,P55786 7 +Aromatic amino acid transmembrane transporter activity 0.8928220255653994 1.3082668430262914 0.1907828171730528 1.0 0.5863081698489431 2 P30825 1 +Calcium cation antiporter activity 0.892822025565388 1.3082668430262443 0.1907828171730687 1.0 0.5863081698489431 2 O95202 1 +Metallocarboxypeptidase activity 0.6782055929179087 1.294277534387522 0.195569573544343 1.0 0.5978894733092142 5 P16870 1 +Sphingosine n acyltransferase activity 0.8865945591609428 1.2825906237396891 0.1996355368202187 1.0 0.60171761872746 2 Q96G23 1 +Pattern recognition receptor activity 0.8829891838741504 1.26774094618673 0.2048904772125339 1.0 0.6067985082758719 2 Q5KU26 1 +Cytokine binding 0.6082993195548657 1.2659786941565667 0.2055207102529008 1.0 0.6067985082758719 7 P06756,O14786,P15260 3 +Cytokine receptor binding 0.4575812728272282 1.261003894321884 0.2073074440748592 1.0 0.6072168258785758 19 P62942,Q3ZCQ8,O00560,Q9NZ08,Q96J02 5 +Thiol oxidase activity 0.8182096347242913 1.2600179218050829 0.2076628971619372 1.0 0.6072168258785758 3 Q6ZRP7 1 +Insulin like growth factor i binding 0.8170491803278541 1.2553938446575557 0.2093358227397455 1.0 0.6105379651418491 3 P06756,P98164 2 +Fibronectin binding 0.8154098360655766 1.248862460527031 0.2117153839067325 1.0 0.6123568368513637 3 P05556,P06756 2 +Phosphoric diester hydrolase activity 0.54011704659401 1.239503958578974 0.215158923682877 1.0 0.6133412234034169 10 P09601,Q8IV08 2 +Oxidoreductase activity acting on nad p h heme protein as acceptor 0.8088524590163884 1.2227492460129763 0.2214244205231987 1.0 0.6133412234034169 3 P16435,Q7KZN9 2 +Acetylgalactosaminyltransferase activity 0.8078688524590086 1.218834159706932 0.2229071433476881 1.0 0.6133412234034169 3 Q10472,Q10471 2 +Polypeptide n acetylgalactosaminyltransferase activity 0.8078688524590086 1.218834159706932 0.2229071433476881 1.0 0.6133412234034169 3 Q10472,Q10471 2 +Myosin binding 0.5778502545758103 1.2181089098361988 0.2231825884828153 1.0 0.6133412234034169 8 Q96J84 1 +Oxidative phosphorylation uncoupler activity 0.870862012454946 1.2178892554230356 0.2232660598134912 1.0 0.6133412234034169 2 P12235 1 +Nucleobase transmembrane transporter activity 0.870862012454946 1.2178892554230356 0.2232660598134912 1.0 0.6133412234034169 2 P12235 1 +Volume sensitive anion channel activity 0.8067310051950789 1.2143058216427822 0.2246309633940395 1.0 0.6133412234034169 3 Q9C0H2 1 +Inorganic anion exchanger activity 0.8698787282858071 1.213854535779189 0.2248032766875438 1.0 0.6133412234034169 2 P04920 1 +Serine transmembrane transporter activity 0.7046210950530525 1.205557682965217 0.2279880840510721 1.0 0.619591146068208 4 Q96QD8,Q15758 2 +Peptidase activator activity involved in apoptotic process 0.8035918026264092 1.2018165914818335 0.229434595783458 1.0 0.6210578542651306 3 P53634 1 +Iron ion transmembrane transporter activity 0.8666011143887252 1.200414203970748 0.229978515149936 1.0 0.6210578542651306 2 Q8N4V1 1 +Structural constituent of postsynapse 0.6983264834921576 1.1790286467826336 0.238386769002507 1.0 0.6304091670326057 4 P07196 1 +Nitric oxide synthase regulator activity 0.6519865142033934 1.17573438791219 0.2397010324864237 1.0 0.6304091670326057 5 P0DP25 1 +Signaling receptor binding 0.4090991382695965 1.1638555683650162 0.244482548301046 1.0 0.635746363874765 178 Q14344,P43490,Q13501,P62942,P51572,P05556,P04114,Q08431,O14654,Q96J02,Q9BUN8,P07237,P05067,Q5ZPR3,P48681,P04062,Q15375,P27824,Q07021,O00560,P06280,P08069,Q9NZ08,P0DP25,P07942,O15258,P06756,P01889,Q92520,P16870,Q96JJ3,Q9NUQ9,Q92542,Q9NPF0,P04899,O94813,Q9Y624,O75381,Q8WUM4,P04439,Q03518,O75955,Q92896,Q7KYR7,O75386,P08754,Q07954,P08236,Q3ZCQ8,P11233,Q96CW1,Q9BQE5 52 +Lamin binding 0.5665746442557291 1.1592145600033466 0.2463687380153887 1.0 0.6370654307636731 8 Q5SNT2,O94901,Q14739,P42167 4 +Magnesium ion transmembrane transporter activity 0.7917556050862719 1.154788067548046 0.248177224688624 1.0 0.638170006342176 3 Q8N4V1 1 +P type calcium transporter activity 0.854146181579821 1.1494757745738764 0.2503598504168274 1.0 0.6423435122334035 2 P16615 1 +L serine transmembrane transporter activity 0.7888524590163979 1.1432703534423496 0.2529263599989511 1.0 0.6451265925362654 3 Q96QD8,Q15758 2 +Laminin binding 0.6430086354269131 1.135102179447255 0.2563325085061008 1.0 0.6495006522659154 5 P14543,O94813 2 +Protein prenyltransferase activity 0.8433300557194494 1.1054393116803287 0.2689692775638839 1.0 0.6596480950322556 2 P49356 1 +Acid phosphatase activity 0.6796969757441912 1.100580051729866 0.2710794714538995 1.0 0.6596480950322556 4 P11117 1 +Arylesterase activity 0.8403802032120652 1.0934659810332987 0.2741892575309337 1.0 0.6655452030435624 2 Q9HDC9 1 +Modified amino acid binding 0.4342007885483116 1.074146470860586 0.2827570393693037 1.0 0.6726866882079355 21 Q8WTV0,Q06481,Q14108,Q08431,Q99735 5 +Protein self association 0.4980957348280702 1.073893372310449 0.2828704741657164 1.0 0.6726866882079355 12 Q9Y282,P53634 2 +Histone h3 methyl lysine 36 demethylase activity 0.8331694526384787 1.0642706601995495 0.2872061052099137 1.0 0.6756828350545012 2 Q8IUF8 1 +Oxidoreductase activity acting on nad p h 0.4363695431556225 1.0639555035251087 0.2873488574037444 1.0 0.6756828350545012 28 Q13423,O96000,Q9Y6M9,O95831,Q9P0J0,Q7KZN9,P16435,O43676,P03886,O75438,P03915 11 +Activin binding 0.82956407735171 1.0497142215718187 0.2938495231786699 1.0 0.675971608352617 2 P36896 1 +C x3 c chemokine binding 0.8289085545722863 1.0470706994726686 0.2950669718999519 1.0 0.675971608352617 2 P06756 1 +Signaling receptor regulator activity 0.439525832557202 1.0429056759966004 0.2969919805662737 1.0 0.6781362252950849 18 Q9NPF0,Q15375,P05067,P43490 4 +Catalytic activity acting on a glycoprotein 0.7615272243294473 1.035318195484628 0.3005203350809102 1.0 0.6797177447121754 3 O43505 1 +Semaphorin receptor activity 0.7555671079888169 1.011908974436724 0.3115815778849251 1.0 0.6876625269880672 3 O15031 1 +Anion cation symporter activity 0.7540983606557246 1.0061493543429243 0.3143437303701519 1.0 0.690460238182299 3 Q15043,P55011 2 +O methyltransferase activity 0.5344517976875965 0.9909658536520884 0.3217022541025449 1.0 0.6954857744731874 8 P21964 1 +Lipid kinase activity 0.8128482464765817 0.98262950487643 0.3257898175782325 1.0 0.6978067007696034 2 Q8TCT0 1 +2 acylglycerol 3 phosphate o acyltransferase activity 0.8115372009177306 0.977398671028476 0.3283718206881136 1.0 0.6981645954002125 2 Q96N66 1 +Chaperone binding 0.4228466923329834 0.9737212388902704 0.3301949687794703 1.0 0.7002506157239756 40 P98164,P01889,P02786,P55011,P53634,Q04656,Q96KC8,Q14108 8 +Cytochrome b5 reductase activity acting on nad p h 0.8085873484103585 0.965647016826301 0.3342208400689466 1.0 0.702387353513826 2 P16435 1 +Mannosyl oligosaccharide mannosidase activity 0.8069485414618258 0.959129165034525 0.337493679513454 1.0 0.7050548314065197 2 P33908 1 +Fibroblast growth factor binding 0.6025777422662455 0.9524699884910236 0.3408586793245098 1.0 0.7072307328499561 5 Q92896 1 +N acyltransferase activity 0.4158835507119756 0.9497139181509048 0.3422576357393434 1.0 0.7090718731460838 19 Q96QD8,Q96G23,Q86UY6 3 +Monosaccharide binding 0.4209658655428346 0.940584520182567 0.3469178177529 1.0 0.7108206871113752 29 O00462,P35613,O75503,P11717,Q5KU26,P19021 6 +L glutamine transmembrane transporter activity 0.7994100294985413 0.9292514961084344 0.352758765566094 1.0 0.7138659131274584 2 Q96QD8 1 +G protein activity 0.4577919175664425 0.9164722674966314 0.359419246536472 1.0 0.718568864350028 14 P20339,P61020,Q15286,Q9H0U4,P51149,P62820,P11234,P51148,P11233 9 +Chemokine binding 0.7283262652618043 0.9057776064371283 0.3650535760990434 1.0 0.7211600467437929 3 P06756 1 +1 phosphatidylinositol 4 kinase activity 0.793182563094084 0.9047069395289214 0.3656206637416783 1.0 0.7211600467437929 2 Q9BTU6 1 +Opsonin binding 0.6327942870962241 0.9044002638759432 0.3657831983123278 1.0 0.7211600467437929 4 P06756 1 +Lysophospholipid acyltransferase activity 0.7258083767293722 0.8960520405651836 0.3702249697676425 1.0 0.7278465363091525 3 Q96N66 1 +Prenyltransferase activity 0.6293618591377979 0.8901742768905337 0.3733723145182541 1.0 0.7319576066793497 4 P49356,P53611 2 +Thiolester hydrolase activity 0.4440571651073155 0.8788802545649941 0.3794662057798654 1.0 0.7407607904378781 15 Q9UMR5 1 +Channel regulator activity 0.44355259614538 0.8755880827604036 0.381254006327363 1.0 0.7413979862693579 15 P62942,O15400,Q96PU5,Q9UNK0 4 +Nadp retinol dehydrogenase activity 0.5853869195406713 0.8753244821739036 0.3813973767749294 1.0 0.7413979862693579 5 Q9Y394,Q8NBN7,Q8TC12 3 +G protein coupled receptor binding 0.4118345163728776 0.8682411521026491 0.3852623302778466 1.0 0.7457731700629824 29 P48681,Q8WUM4,O75386,Q07021,O00560,P08754,P04899,P0DP25,Q96J02,P11233 10 +Channel inhibitor activity 0.5439418588097873 0.8669694773038972 0.3859587337470445 1.0 0.7460792259043287 6 P62942,Q96PU5 2 +Low density lipoprotein particle receptor binding 0.4689872174632237 0.8648623853923566 0.3871143250422255 1.0 0.7472708280063016 11 P04114,Q96CW1 2 +Dicarboxylic acid transmembrane transporter activity 0.5268656085671872 0.8564781614773065 0.3917333473586959 1.0 0.7517708989333184 7 Q9UBX3,Q02978,Q15758 3 +Deoxyribonuclease activity 0.4134482824332677 0.8546777839396549 0.3927295527400452 1.0 0.7517708989333184 18 Q8IV08 1 +Nucleotidase activity 0.541212263963093 0.8537565598153622 0.3932398883178012 1.0 0.7517708989333184 6 Q9NX62 1 +Protein phosphatase 2a binding 0.4642774335309201 0.8374327329653819 0.4023493729750236 1.0 0.7653423426119048 11 Q15257,Q9UPR3,P78318,Q86XL3,O43815 5 +Demethylase activity 0.5041821061166532 0.8326468818038277 0.4050439102951959 1.0 0.769028574889235 8 Q8IUF8,Q16850,Q9Y2K7 3 +Dopamine receptor binding 0.5738188976377978 0.823722513298566 0.4100972443170354 1.0 0.7754362627877369 5 Q14344,Q15334,P50570,Q96QK1 4 +Ubiquitin binding 0.4040634255186869 0.80670527615727 0.4198363036260053 1.0 0.785316519506314 29 Q13501,Q96FW1 2 +C4 dicarboxylate transmembrane transporter activity 0.5306343705105958 0.8026871769381317 0.4221555663910477 1.0 0.7864349664220324 6 Q9UBX3,Q02978,Q15758 3 +Phosphatidylglycerol binding 0.7006557377049114 0.7998841908202716 0.4237778981571587 1.0 0.788397539390365 3 O60313,Q00169 2 +Molecular carrier activity 0.4031664190732975 0.7930301203826156 0.4277602741787687 1.0 0.7936756894401251 33 P40855,Q8N4V1,Q04656,Q15070,Q96P70 5 +Phosphatidylinositol 3 kinase binding 0.5609141667360675 0.7665488482054419 0.4433497981503209 1.0 0.8051350376740479 5 O14654,P0DP25 2 +Potassium chloride symporter activity 0.7538511963290894 0.7531436749828534 0.4513635817263601 1.0 0.8051350376740479 2 P55011 1 +Cation chloride symporter activity 0.7538511963290894 0.7531436749828534 0.4513635817263601 1.0 0.8051350376740479 2 P55011 1 +Calcium activated cation channel activity 0.7531956735496792 0.7506762727026541 0.452847506009804 1.0 0.805708142913464 2 Q4KMQ2 1 +Glycolipid mannosyltransferase activity 0.6872131147540905 0.7493504666850352 0.4536459976167788 1.0 0.8060940419190454 3 Q2TAA5,Q9H553 2 +Armadillo repeat domain binding 0.6864341553494089 0.7464433728742174 0.4553996268404638 1.0 0.8081739856605415 3 Q9P1Z2 1 +Leukotriene c4 synthase activity 0.7505735824319997 0.7408285047144036 0.4587974295586383 1.0 0.8100550794500289 2 Q99735 1 +Calcium channel inhibitor activity 0.6832786885245787 0.7346922957105936 0.4625269134372085 1.0 0.8114712683847733 3 Q9NRX4,P62942 2 +Signal sequence binding 0.3922171128100388 0.7255611530283338 0.4681078430070022 1.0 0.8181557003880265 26 O43731,P40855,P24390 3 +Lysophosphatidic acid phosphatase activity 0.7456571615863774 0.7224604207031685 0.4700114508769699 1.0 0.818179208073649 2 Q9NPH0 1 +Inositol phosphate phosphatase activity 0.6796721311475362 0.7213121107397482 0.4707175073851042 1.0 0.818179208073649 3 Q10713,Q9UNW1 2 +Atpase activator activity 0.4424522376837322 0.7108568821585406 0.4771729275991032 1.0 0.8242230929271466 11 P54709,Q96KC8,Q8NFQ8 3 +Peroxisome targeting sequence binding 0.7423795476893047 0.7102871646182692 0.4775260776482675 1.0 0.8242230929271466 2 P40855 1 +Mhc class i protein binding 0.478000544494342 0.6969666010060932 0.4858236957405268 1.0 0.8317886762258345 8 Q03518 1 +Fk506 binding 0.4928637342197978 0.687429636124843 0.4918120273496797 1.0 0.8317886762258345 7 Q9Y680 1 +Macrolide binding 0.4928637342197978 0.687429636124843 0.4918120273496797 1.0 0.8317886762258345 7 Q9Y680 1 +Peptide hormone binding 0.6699475380079618 0.6855193375436943 0.4930162623507694 1.0 0.8317886762258345 3 P42892 1 +Molecular adaptor activity 0.3232629948469493 0.6580178389647505 0.5105266683675691 1.0 0.8441592511372517 110 O95249,Q13190,P51809,O60499,Q9P2W9,O15400,O00560,Q92542,Q7KZN9,Q9NRX5,P61962,Q96D46,Q86Y82,Q9BTX1,Q13277,Q9UNK0 16 +Syntaxin 1 binding 0.6563934426229412 0.6363880579485217 0.5245235225995342 1.0 0.8460066508088399 3 O00186,O75150 2 +Protease binding 0.3785560376089013 0.6322721438930239 0.5272090625972599 1.0 0.8476934579580072 24 P06756,P07602,Q9BUN8,P01130,Q9NZJ7 5 +Insulin receptor binding 0.4806226040694959 0.6274862887695579 0.5303405211151855 1.0 0.8494698755270578 7 P08069,O14654,Q8WWQ0,P18031 4 +G protein coupled serotonin receptor binding 0.7187807276302808 0.6245028843553523 0.5322973766773424 1.0 0.8494698755270578 2 P08754 1 +Phosphatidylcholine transfer activity 0.7181252048508642 0.6221702672824113 0.5338299145628191 1.0 0.8494698755270578 2 Q00169 1 +Phospholipid transfer activity 0.7181252048508642 0.6221702672824113 0.5338299145628191 1.0 0.8494698755270578 2 Q00169 1 +Phosphatidylinositol transfer activity 0.7181252048508642 0.6221702672824113 0.5338299145628191 1.0 0.8494698755270578 2 Q00169 1 +Phosphatidylcholine transporter activity 0.6508196721311355 0.6164633690993533 0.5375887410373792 1.0 0.8525148685100773 3 P48739,Q00169 2 +Molecular function activator activity 0.4204587694619475 0.6114116096623515 0.5409271186703493 1.0 0.8558504411839087 12 P54709,Q96KC8,Q8NFQ8 3 +Gdp binding 0.3745268780311488 0.5952649173669269 0.551666402729909 1.0 0.8659225755194269 25 P20339,P62070,P61026,Q15286,P61020,Q9HB90,P08754,P51149,P61019,P11234,P51148,Q9NP72,P11233,P51151 14 +Phosphatidylinositol binding 0.3659815044418426 0.5723422556050464 0.5670901279048617 1.0 0.8717886527287082 53 Q9H0H5,Q9Y4P8,Q9H4A5,Q8WTV0,O75386,Q06481,O00560,O43292,Q9BWH2,Q92643,Q9H490 11 +Protein kinase a regulatory subunit binding 0.4805884764592594 0.5658392203672274 0.571503082094714 1.0 0.8717886527287082 6 P17612,Q96M27 2 +Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor 0.6991150442478097 0.5558437918285067 0.5783176457688453 1.0 0.8750526823532965 2 O95881 1 +Carbon sulfur lyase activity 0.4769039421098907 0.54885841757755 0.5831026166219571 1.0 0.8771250588553836 6 P53701 1 +Protein phosphatase activator activity 0.5429000626052987 0.5446187854664984 0.5860157319625434 1.0 0.8771250588553836 4 P0DP25 1 +Phosphatase activator activity 0.5429000626052987 0.5446187854664984 0.5860157319625434 1.0 0.8771250588553836 4 P0DP25 1 +17 beta hydroxysteroid dehydrogenase nadpplus activity 0.6945263847918826 0.5402391206435703 0.5890321368744407 1.0 0.8778533624861848 2 Q53GQ0 1 +Nf kappab binding 0.4023878142264719 0.5348765628751442 0.5927352158739885 1.0 0.8791687479920814 13 Q86UE4 1 +Dynactin binding 0.538865201705469 0.5293798605993693 0.596541966054855 1.0 0.8791687479920814 4 Q9UNH7,P43034,Q9Y5X3 3 +Phosphatidylcholine binding 0.4123752460292262 0.5188670919952664 0.603853427472564 1.0 0.8831855320979127 10 P21796,P45880 2 +Nadplus kinase activity 0.62262483208514 0.5185370589106068 0.6040836106990053 1.0 0.8831855320979127 3 Q8TCT0 1 +High density lipoprotein particle binding 0.6220310113116327 0.5165310204045782 0.6054835791036732 1.0 0.8833293550202109 3 Q9BQE5 1 +Guanyl nucleotide exchange factor activity 0.3648288309661391 0.4991976979033223 0.6176401162163918 1.0 0.8869146266945817 29 Q15042,Q02818,Q6IAA8,P80303 4 +Phospholipase binding 0.5301666061771513 0.4969030050550689 0.6192574523040979 1.0 0.8869146266945817 4 P07196 1 +Phosphatidylinositol phosphate 4 phosphatase activity 0.6794493608652923 0.4901782133006512 0.6240077962007393 1.0 0.8869146266945817 2 Q9NTJ5 1 +Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity 0.6794493608652847 0.4901782133006273 0.6240077962007562 1.0 0.8869146266945817 2 Q10713 1 +Phosphatidylinositol phosphate 5 phosphatase activity 0.6794493608652847 0.4901782133006273 0.6240077962007562 1.0 0.8869146266945817 2 Q10713 1 +Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity 0.6794493608652847 0.4901782133006273 0.6240077962007562 1.0 0.8869146266945817 2 Q10713 1 +Inositol trisphosphate phosphatase activity 0.6794493608652847 0.4901782133006273 0.6240077962007562 1.0 0.8869146266945817 2 Q10713 1 +Phosphatidylinositol 4 5 bisphosphate phosphatase activity 0.6794493608652847 0.4901782133006273 0.6240077962007562 1.0 0.8869146266945817 2 Q10713 1 +Phosphatidylinositol trisphosphate phosphatase activity 0.6794493608652847 0.4901782133006273 0.6240077962007562 1.0 0.8869146266945817 2 Q10713 1 +Inositol polyphosphate 5 phosphatase activity 0.6794493608652847 0.4901782133006273 0.6240077962007562 1.0 0.8869146266945817 2 Q10713 1 +Inositol tetrakisphosphate phosphatase activity 0.6794493608652845 0.490178213300626 0.6240077962007571 1.0 0.8869146266945817 2 Q9UNW1 1 +Copper ion binding 0.4042474143310972 0.4747515966482806 0.6349640368801424 1.0 0.8898484884892592 10 P19021,O60888 2 +Phosphatidylinositol kinase activity 0.6010692607899196 0.4474097363691744 0.6545792471905756 1.0 0.9050131278321192 3 Q9BTU6 1 +Dolichyl phosphate mannose protein mannosyltransferase activity 0.6640445755489943 0.4410964772491905 0.6591431536977468 1.0 0.905423598637341 2 O60762 1 +Cytoskeletal anchor activity 0.4482697940186641 0.4200862564470866 0.6744224423171754 1.0 0.9187497859912528 6 O00560 1 +Guanyl nucleotide binding 0.3060495610499406 0.4196618768309293 0.6747324787764271 1.0 0.9187497859912528 110 P20339,Q14344,Q969Q5,P62820,P51148,Q9NP72,Q9NR31,P51151,P40616,Q9Y5M8,P61020,Q6DD88,Q9H0U4,Q9Y5P6,Q5HYI8,Q9Y6B6,Q9BZG1,P04350,Q14964,P04899,P61019,Q8IWA4,Q9NVN8,Q9H223,Q9HB90,O00429,P08754,Q8WZA9,Q8NHH9,O60313,Q9H4M9,P51149,P55010,P11233 34 +Clathrin binding 0.345069901201509 0.4080459531698432 0.6832399380726022 1.0 0.9236243198984562 21 Q07954 1 +Nuclear import signal receptor activity 0.3849528138127012 0.4078247948440449 0.6834023087514276 1.0 0.9236243198984562 12 Q92973,Q96P70 2 +Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.6515896427400867 0.4030752316480061 0.6868928808937564 1.0 0.9252026558977128 2 O95864 1 +Sphingolipid transporter activity 0.6506063585709538 0.4001402204062425 0.6890532416986113 1.0 0.9272114495090052 2 P48739 1 +Dipeptidyl peptidase activity 0.5845902606104965 0.3955959283205492 0.6924031413132126 1.0 0.9280210787730148 3 P53634 1 +Tau protein kinase activity 0.5836065573770415 0.3925793826730779 0.6946301697078374 1.0 0.9280210787730148 3 Q00535,O75116 2 +Misfolded protein binding 0.3845367129398801 0.3856751060735928 0.6997373015963413 1.0 0.931431817035954 11 P48723 1 +Pre mrna intronic binding 0.4691601049868856 0.3827283957793774 0.7019211578545059 1.0 0.9327308578875878 5 Q13148,P22626,P14866,Q9BWF3 4 +Serine type endopeptidase inhibitor activity 0.4127539160185156 0.3730707472084821 0.7090957898639978 1.0 0.9327308578875878 8 P05067 1 +Organic cation transmembrane transporter activity 0.4664278072810268 0.372239365786729 0.7097146389300504 1.0 0.9327308578875878 5 O43808,Q70HW3,Q9HC21 3 +Phosphatidylinositol 3 phosphate binding 0.4664054459949815 0.372153828109977 0.7097783208337805 1.0 0.9327308578875878 5 Q9Y4P8 1 +Cation channel activity 0.3372967123669794 0.3622699705888602 0.7171502962805896 1.0 0.9327308578875878 20 P06756,Q4KMQ2 2 +D1 dopamine receptor binding 0.573442622950817 0.3619447454300907 0.7173933215707926 1.0 0.9327308578875878 3 Q15334,Q96QK1 2 +Chemokine receptor binding 0.4631495319854297 0.359752984091698 0.7190318655113486 1.0 0.9327308578875878 5 Q96J02 1 +Histone h3 methyl lysine 4 demethylase activity 0.5726746303400019 0.3596704106695486 0.71909362207461 1.0 0.9327308578875878 3 Q8IUF8 1 +Cysteine type peptidase activity 0.3466900723126518 0.3584833241038679 0.7199816452294625 1.0 0.9327308578875878 49 Q99538,P53634,Q96FW1,Q92820,P07858 5 +Electron transfer activity 0.3441348040738171 0.3575750184201887 0.7206613762430294 1.0 0.9327308578875878 52 P14406,O96000,Q9Y6M9,Q7KZN9,Q9P0J0,P00403,P16435,Q9UDW1,O43676,Q15526,P03886,O75438,P13073,P03915 14 +Protein kinase activity 0.2797162446642663 0.3539003874194201 0.723413536686258 1.0 0.9353089196335388 83 P46020,Q15375,Q13501,P11717,P00533,Q86UE8,P36896,P31751 8 +Phosphoserine residue binding 0.4880288619219377 0.3482050697701237 0.7276861806269495 1.0 0.9364652240937344 4 P62258,P31946,O95104 3 +Protein demethylase activity 0.4584019327118677 0.3418672116470777 0.7324508258502056 1.0 0.9375984509292156 5 Q8IUF8,Q9Y2K7 2 +Lipase activity 0.3532654834669294 0.339179058780481 0.7344748439003235 1.0 0.9375984509292156 16 P09601,Q8NCC3,P38571,Q8NHP8,Q8IV08 5 +14 3 3 protein binding 0.4804854050508219 0.3233576313339005 0.7464244126831705 1.0 0.9482531952143668 4 Q9UBF8,P78362,O14974 3 +Structural constituent of eye lens 0.5595143391495451 0.3216204470859329 0.7477402517011258 1.0 0.9490549348514288 3 P08670 1 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.3341130383486782 0.3124979424867354 0.7546621264847122 1.0 0.9560893119815458 23 O96000,Q9Y6M9,Q9P0J0,O43676,P03886,O75438,P03915 7 +Protein phosphatase regulator activity 0.3282185094189755 0.309293939603526 0.7570979406179896 1.0 0.9581173766739643 19 Q86XL3,Q01105,P0DP25 3 +Cdp alcohol phosphatidyltransferase activity 0.5504498057645812 0.2964678155259977 0.7668728422560165 1.0 0.9618875650378632 3 O14735 1 +Transferrin receptor binding 0.4624467038373185 0.2665074726083432 0.78984840514317 1.0 0.975386289583575 4 Q13596,O14920,O60749 3 +Phosphatidylinositol phosphate binding 0.33362479676676 0.2535770683765089 0.7998223144702636 1.0 0.9806949996772204 31 Q9H0H5,Q9Y4P8,Q9H4A5,O75386,O00560,Q9BWH2 6 +Sh3 domain binding 0.3214829120126848 0.2534395532699003 0.7999285659986066 1.0 0.9806949996772204 20 P98164 1 +Ubiquitin like protein binding 0.3339802542267773 0.2390137830020179 0.8110948951579127 1.0 0.9849516400844636 35 Q13501,Q96FW1 2 +Cytokine activity 0.403812589644244 0.2356727712225696 0.813686600214077 1.0 0.9849516400844636 6 P43490 1 +Profilin binding 0.4480157428665096 0.2238614808677781 0.8228650888926019 1.0 0.9874806649919908 4 P42858,Q14247,Q16643 3 +Glucocorticoid receptor binding 0.5771878072762938 0.2122865279111762 0.8318835050866327 1.0 0.991393411908919 2 Q02790 1 +Jun kinase binding 0.5689937725335887 0.1954966297508153 0.8450041758499081 1.0 0.9984448318226534 2 O60271 1 +Cullin family protein binding 0.4128848326956307 0.1841451217836909 0.8538996096151756 1.0 1.0 5 O60826,Q16531 2 +N6 methyladenosine containing rna binding 0.4120734908136498 0.1815897679595835 0.8559046793292475 1.0 1.0 5 Q9H6S0,Q96MU7,P22626,Q7Z739 4 +Calcium dependent protein serine threonine phosphatase activity 0.5026229508196672 0.1795288537249831 0.857522463361216 1.0 1.0 3 Q13555,P49593 2 +Cyclin dependent protein serine threonine kinase regulator activity 0.3885789300951709 0.1783651822350939 0.8584361913650795 1.0 1.0 6 P11802,O95067,P49736,P20248,P14635 5 +Oxidative rna demethylase activity 0.556866601114383 0.1722773557297542 0.8632194856939117 1.0 1.0 2 Q9C0B1 1 +N acetyltransferase activity 0.329595134284354 0.1710237044231202 0.8642051267513375 1.0 1.0 15 Q86UY6 1 +Carbon nitrogen lyase activity 0.4082436919383887 0.1696622424536996 0.8652757696500419 1.0 1.0 5 P19021 1 +Solute proton symporter activity 0.4260413250245835 0.1642551223749155 0.8695303089369577 1.0 1.0 4 Q00325,Q9H936,O00400 3 +Metalloaminopeptidase activity 0.3394581709052063 0.156923482629169 0.8753051526746216 1.0 1.0 11 Q9UIQ6,P55786 2 +Quaternary ammonium group binding 0.3283729072619463 0.1434498075108858 0.8859349489823516 1.0 1.0 14 P21796,Q14108,P45880 3 +Phosphatase regulator activity 0.3054943796737051 0.1388754307843768 0.8895485862018311 1.0 1.0 21 Q86XL3,Q01105,P0DP25 3 +Alcohol dehydrogenase nadpplus activity 0.3695090840421099 0.1385900731614732 0.889774088075225 1.0 1.0 7 Q9Y394,Q8NBN7,Q8TC12 3 +Cysteine type endopeptidase activity 0.3134744882737178 0.1379910198489446 0.8902475147732236 1.0 1.0 27 Q9UPU5,Q99538,P53634,O43292,Q92643,P07858 6 +Class i dna apurinic or apyrimidinic site endonuclease activity 0.5355621107833395 0.1362069527764858 0.8916576788742494 1.0 1.0 2 P78549 1 +Translation initiation factor binding 0.3134845474198715 0.1353362605089302 0.8923460170535429 1.0 1.0 17 P55010,Q9UNK9 2 +Oxidoreductase activity acting on a sulfur group of donors 0.3099817839391926 0.1309933824940984 0.8957805423017122 1.0 1.0 25 Q9UHG3,P09622,Q9H3N1,Q96JJ7,P07237,Q6ZRP7 6 +Single stranded dna 3 5 exodeoxyribonuclease activity 0.5316289741068411 0.1302007245830912 0.896407621326553 1.0 1.0 2 Q07864 1 +Guanylate kinase activity 0.4750819672131113 0.1252806057168323 0.9003014056028662 1.0 1.0 3 Q00013,Q14168 2 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.3339183851847315 0.1246326456207546 0.9008143824261234 1.0 1.0 10 Q9H0H5 1 +Receptor tyrosine kinase binding 0.3119176503418189 0.099722020284093 0.920565018023241 1.0 1.0 16 Q13501 1 +Protein arginine n methyltransferase activity 0.3657414776491037 0.0995250369492352 0.9207214099726716 1.0 1.0 6 Q7L592,Q6P2P2 2 +Ether hydrolase activity 0.3818375498966835 0.093801665297397 0.925266708803686 1.0 1.0 5 P34913,P09960 2 +Epoxide hydrolase activity 0.3818375498966835 0.093801665297397 0.925266708803686 1.0 1.0 5 P34913,P09960 2 +Calmodulin dependent protein phosphatase activity 0.502458210422801 0.0918064421272801 0.9268518256037804 1.0 1.0 2 P49593 1 +Toxic substance binding 0.4955752212389264 0.0842681157599039 0.9328432621466508 1.0 1.0 2 P34913 1 +Epidermal growth factor receptor binding 0.3606826386609696 0.0833256198493612 0.9335926294338684 1.0 1.0 6 Q92600,Q13596,P62993,P18085,O60749 5 +Myosin v binding 0.4896755162241772 0.0782448583655459 0.9376332795550169 1.0 1.0 2 P61026 1 +Plus end directed microtubule motor activity 0.3560879553659289 0.069035533569275 0.9449613352601824 1.0 1.0 6 P33176,Q96Q89,Q12756,Q86Y91,O60333 5 +Protein tyrosine kinase activator activity 0.467059980334304 0.0586846640563718 0.9532032745947157 1.0 1.0 2 Q13177 1 +Copper chaperone activity 0.3775641355684846 0.058037660154371 0.9537186306043832 1.0 1.0 4 Q04656,O75880 2 +Metallochaperone activity 0.3775641355684846 0.058037660154371 0.9537186306043832 1.0 1.0 4 Q04656,O75880 2 +Spectrin binding 0.3671259842519687 0.0566883366027326 0.9547934651180592 1.0 1.0 5 P35611,Q12955,P11171,Q13561 4 +E box binding 0.4252459016393402 0.0524170696025398 0.9581963732376872 1.0 1.0 3 O14744,Q13547 2 +Ubiquinone binding 0.4470665355621059 0.0456062969752321 0.963624050136078 1.0 1.0 2 P21912 1 +Tpr domain binding 0.3666775992128544 0.0392255161929746 0.9687105903078492 1.0 1.0 4 O76094,Q9UNE7,P08238 3 +Mdm2 mdm4 family protein binding 0.3439448638004569 0.0332758466342592 0.9734546146843492 1.0 1.0 6 P61289,P04637,P61927,P60866,Q96JB5 5 +Bubble dna binding 0.4172402490986492 0.032154371213585 0.9743489438423356 1.0 1.0 2 Q01831 1 +Long chain fatty acid coa ligase activity 0.3614299770416472 0.0308210197477463 0.9754122770475148 1.0 1.0 4 P33121,O60488,O95573 3 +Arachidonate coa ligase activity 0.3614299770416472 0.0308210197477463 0.9754122770475148 1.0 1.0 4 P33121,O60488,O95573 3 +Dna apurinic or apyrimidinic site endonuclease activity 0.3597900951131491 0.0282824808001062 0.9774368533071792 1.0 1.0 4 P23396,Q96FZ2,P78549 3 +Ubiquitin like protein ligase binding 0.2740360170591284 0.0266469578194636 0.9787413196176302 1.0 1.0 106 P10644,Q13501,Q9UPR3,Q96FW1,Q9NQC3,P00533,Q96HY6,Q8TCT9,O76024,O14828,Q96J02,Q9BUN8,P36896,P11233,Q9UNK0 15 +Protein tyrosine kinase inhibitor activity 0.3982300884955679 0.0265713930688588 0.9788015902244392 1.0 1.0 2 O95684 1 +Enzyme activator activity 0.2716002246920665 0.0249652850805479 0.980082653465366 1.0 1.0 103 Q9H0H5,P61289,O75569,Q15042,Q9BXK5,Q9P035,P53634,O43169,P10619,P07602,Q9HCU5,P0DP25,P17900,Q99735,Q8IZ81,O14786,P05067,Q9NZJ7 18 +Lipase activator activity 0.3880694854146129 0.0243324661104332 0.9805874165809674 1.0 1.0 2 Q9Y263 1 +Monocarboxylic acid transmembrane transporter activity 0.361193051458532 0.0203121823844188 0.983794337655122 1.0 1.0 2 P53985 1 +5 deoxyribose 5 phosphate lyase activity 0.3251392985906187 0.0177883595098055 0.9858076910576914 1.0 1.0 2 P12956 1 +Vascular endothelial growth factor receptor binding 0.3195673549655768 0.017579864218073 0.9859740202217524 1.0 1.0 2 Q9Y5K6 1 +Trna cytosine methyltransferase activity 0.3189118321861609 0.0175575898284308 0.9859917898707458 1.0 1.0 2 Q08J23 1 +Death domain binding 0.3512627090849458 0.0157501522713417 0.9874337162218908 1.0 1.0 4 Q13546,Q07820,P63244 3 +Calcium channel regulator activity 0.3427416711989013 0.0037970830797413 0.9969703733147024 1.0 1.0 5 P62942 1 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e4fdc430329ec0b58d1a2edb6238bd6a4280f72f --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "3 phosphoadenosine 5 phosphosulfate binding", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin activated receptor activity", "Activin binding", "Activin receptor activity type i", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel activator activity", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Copper ion transmembrane transporter activity", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidine deaminase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor activity", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxycytidine deaminase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix protein binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Icosanoid binding", "Identical protein binding", "Ige binding", "Immune receptor activity", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inhibin binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interferon receptor activity", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neuregulin binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neuropeptide binding", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol n acetylglucosaminyltransferase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphorylation dependent protein binding", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Platelet derived growth factor receptor binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion antiporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Potassium proton antiporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein hormone receptor activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Superoxide generating nadph oxidase activator activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toll like receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein serine threonine kinase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor activated receptor activity", "Vascular endothelial growth factor binding", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOBEC3C", "APOL2", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC2", "ASCC3", "ASF1B", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAT1", "BCAT2", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRD8", "BRD9", "BRIX1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf35", "C20orf27", "C2CD5", "CAB39", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASP2", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX4", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2AP", "CD2BP2", "CD302", "CD320", "CD3EAP", "CD46", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CDYL", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPV", "CEP290", "CEP44", "CEP55", "CERK", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHORDC1", "CHRAC1", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLIP1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT4", "CNOT9", "CNP", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "CPD", "CPE", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT2", "CPVL", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPH2", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM83D", "FAM98A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GIGYF2", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3L", "GOPC", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRGQ", "IRS4", "ISCU", "IST1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIRREL1", "KLC1", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L3HYPDH", "LAMB1", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8E", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGT1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAP4K5", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED12", "MED16", "MED17", "MED24", "MED4", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL7A", "MFGE8", "MFN1", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPRIP", "MPST", "MPV17", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL58", "MRPL9", "MRPS15", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MVB12A", "MYBBP1A", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NBR1", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCK1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NENF", "NES", "NEU1", "NF1", "NFS1", "NHP2", "NID1", "NIFK", "NIP7", "NIPBL", "NISCH", "NKRF", "NKTR", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PALD1", "PALLD", "PAM", "PANK4", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHPT1", "PI4K2A", "PI4KB", "PICALM", "PIGA", "PIGK", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIN4", "PINX1", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL5", "REEP4", "REL", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF219", "RNF220", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAGC", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCB", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERINC1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMPDL3A", "SMS", "SMYD2", "SMYD3", "SMYD5", "SNAP23", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPCS3", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNE2", "TAB1", "TACO1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TAX1BP1", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX264", "TFAM", "TFCP2", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TLN1", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM165", "TMEM192", "TMEM201", "TMEM206", "TMEM30A", "TMEM43", "TMEM59", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TROVE2", "TRRAP", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSR1", "TST", "TSTA3", "TTC1", "TTC26", "TTC4", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TULP3", "TWF1", "TWISTNB", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VLDLR", "VPS18", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VRK1", "VRK3", "WARS", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512B", "ZNF622", "ZNF638", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAMP", "AASDHPPT", "ABCD4", "ACOX1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACVR1B", "ADD1", "ADGRE5", "AIFM1", "AKT2", "ALG1", "ALG11", "ALG12", "ALG2", "ANGEL1", "ANK3", "ANKLE2", "ANO6", "AP2M1", "API5", "APLP2", "APMAP", "APOB", "APOL2", "APP", "ARF4", "ARL1", "ARL2", "ARV1", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5J2", "ATP5L", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1E1", "ATP7A", "B4GAT1", "BCAP31", "BCL2L13", "BSG", "BTN2A1", "C1QBP", "CALCOCO1", "CALM3", "CALU", "CAMK2G", "CANT1", "CANX", "CCDC22", "CCDC47", "CCNA2", "CCNB1", "CCNB2", "CD276", "CD2AP", "CD302", "CD320", "CD46", "CD47", "CDH2", "CDIPT", "CDK4", "CDK5", "CDK5RAP3", "CERK", "CERS2", "CETN2", "CLCN3", "CLCN7", "CLN5", "CLPP", "CNNM3", "CNOT9", "COLEC12", "COMT", "COPS4", "COX15", "COX2", "COX4I1", "COX7A2", "CPD", "CPE", "CPT2", "CPVL", "CTSA", "CTSB", "CTSC", "CTTN", "CUTA", "CYB5B", "CYB5R3", "CYP51A1", "DBN1", "DCAF7", "DCTN2", "DDB1", "DDRGK1", "DERL1", "DHCR24", "DHRS7", "DLD", "DNAJC1", "DNM1L", "DNM2", "DPM1", "DSC3", "DSG2", "ECE1", "EFCAB14", "EGFR", "EHD1", "EHD4", "EIF5", "ELMO2", "ELMOD2", "EPB41", "EPDR1", "EPHA7", "EPHX2", "ERAP1", "ERGIC3", "F11R", "FADS2", "FAM3C", "FAM49B", "FGFR1OP", "FKBP14", "FKBP1A", "FKBP4", "FKBP7", "FKBP9", "FKRP", "FLOT1", "FNTB", "FTO", "FUCA1", "FUCA2", "FUNDC2", "GAA", "GALNT1", "GALNT2", "GALNT7", "GBA", "GGCX", "GGH", "GLA", "GLB1", "GLG1", "GLT8D1", "GM2A", "GMPPB", "GNA13", "GNAI2", "GNAI3", "GNL3L", "GNS", "GOLPH3L", "GOSR1", "GPAA1", "GRB2", "GUSB", "HACD3", "HCCS", "HDAC1", "HEXA", "HEXB", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMCES", "HMOX1", "HMOX2", "HNRNPA2B1", "HNRNPL", "HPSE", "HSD17B12", "HSP90AB1", "HSPA13", "HTT", "IFNGR1", "IGBP1", "IGF1R", "IGF2R", "IKBKB", "IMPAD1", "IPO9", "IRGQ", "IRS4", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "KDELR1", "KDELR3", "KDM1B", "KDM2A", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF5B", "KIRREL1", "LAMB1", "LAMP1", "LAMTOR1", "LBR", "LDLR", "LETM1", "LGALS3BP", "LGMN", "LIPA", "LLGL1", "LNPEP", "LRP1", "LRP2", "LSG1", "LTA4H", "M6PR", "MAN1A1", "MAN2B1", "MANBA", "MBOAT7", "MCL1", "MCM2", "MFGE8", "MFN1", "MFSD8", "MGAT1", "MGST2", "MICU1", "MICU2", "MINPP1", "MMGT1", "MPP1", "MPP2", "MPV17", "MRC2", "MSMO1", "MTCH1", "MTDH", "NAA40", "NAGLU", "NAMPT", "NAPA", "NCSTN", "ND1", "ND5", "NDC1", "NDUFA13", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB8", "NDUFB9", "NECTIN2", "NEDD4L", "NEFL", "NES", "NEU1", "NID1", "NMD3", "NNT", "NPC1", "NPC2", "NPEPPS", "NRP1", "NSUN2", "NTHL1", "NUCB1", "NUCB2", "OPA1", "OTUB1", "OXA1L", "P3H4", "P4HA1", "P4HB", "PAFAH1B1", "PAK2", "PAM", "PCYOX1", "PDCD6IP", "PEX14", "PEX19", "PGRMC1", "PGRMC2", "PHIP", "PHKA1", "PHPT1", "PI4K2A", "PI4KB", "PIGK", "PIGU", "PITPNA", "PITPNB", "PLA2G15", "PLAA", "PLBD2", "PLD3", "PLXNB2", "PMPCA", "POLE", "POR", "PPM1F", "PPP1R12A", "PPT1", "PPT2", "PREB", "PRKACA", "PRKAR1A", "PRKRA", "PRMT5", "PRMT9", "PROCR", "PRRC1", "PSAP", "PSMA6", "PSMB2", "PSME3", "PTDSS1", "PTPA", "PTPN1", "PTPRF", "QSOX2", "RAB10", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABGGTB", "RABL3", "RACGAP1", "RACK1", "RALA", "RALB", "RBM4", "RCN2", "RDH11", "RDH13", "RER1", "RHOT2", "RIOX2", "RIPK1", "RNF40", "ROCK2", "RPL37", "RPN1", "RPS20", "RPS3", "RRAGC", "RRAS2", "RTN4", "SACM1L", "SAR1A", "SAR1B", "SCAF4", "SCAMP3", "SCARB1", "SCARB2", "SCO1", "SCPEP1", "SDCBP", "SDF4", "SDHB", "SEC11A", "SERINC1", "SET", "SFXN1", "SFXN4", "SIGMAR1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A10", "SLC25A11", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC29A1", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SLIT2", "SMG5", "SNAP47", "SNX1", "SNX2", "SNX27", "SNX5", "SNX6", "SOAT1", "SORL1", "SORT1", "SPAG9", "SPCS2", "SPPL2A", "SQLE", "SQSTM1", "SRP72", "SRPK2", "SRPRB", "STARD3", "STARD3NL", "STARD7", "STRN", "STT3A", "STUB1", 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alkaline phosphatase level 7 23 2.5499041594704623 0.0107752536172458 5.424757281553398 21.550970873786408 0.2837846270756372 0.4096308965627429 3.0903339262997473 2.8582743162812116 1.1598915940568888 0.2934678757183479 0.000932826900428 0.2183067054048652 0.3896854720293997 0.3513790442708272 0.0029392451780606 +Diarrhea 22 75 2.531459101988478 0.0113589063246795 15.235436893203884 71.36893203883496 -0.0937123546508902 0.4891141680274506 5.321271341758422 8.34189367719314 1.2527606286184891 0.3588826008598239 4.136333909737944e-06 0.0796260892263804 0.1434578911288594 0.000583369042449 1.00126607460285e-05 +Clumsiness 6 18 2.5309626916897523 0.0113749947035275 6.75 20.57766990291262 0.9027704056640264 0.2559090219975202 2.4698423753801175 2.2221930931993956 1.527926415027724 0.282470536898918 0.0033520678687566 0.0230489069918226 0.0803922289273931 0.006410021202963 0.0089113675821019 +Abnormality of glycolipid metabolism 5 7 2.5093130774636907 0.0120966218458944 3.83495145631068 7.228155339805825 0.3163887308740252 0.1681411938672545 1.311614193945771 0.5964160722258837 1.870431483654663 0.2292796295173983 7.792590264445566e-07 0.0009934566258862 1.612359251599596e-06 1.828578586842436e-06 2.2585304294532336e-06 +Abnormal epiphyseal ossification 8 17 2.499748318144785 0.0124281565381862 6.451456310679611 16.274271844660195 1.1227269321938518 0.3276999393402902 3.140724178369711 2.4155680760400804 1.043634905787503 0.3148370578580727 0.0017786180375354 1.0 1.0 0.0213813720021448 0.0002155385692345 +Foam cells 5 6 2.4988841536368662 0.0124585030366954 2.9611650485436893 5.398058252427185 -0.064606162326146 0.1366553329191208 1.1817572081322671 0.893230265545378 1.9405286208577948 0.1862104272675829 5.388804179699288e-06 1.0 0.0743799864466655 0.0007187465088185 3.274702614006158e-07 +Shoulder girdle muscle weakness 4 10 2.476660795672654 0.01326178730194 4.004854368932039 12.42233009708738 0.8387402263996985 0.3756529644451753 2.0785487207705367 2.2836026739757753 0.9187113892871612 0.2934865228782298 0.0429676975440949 0.1471951297158956 0.2732850813359189 0.0449350347407693 0.0203628052401783 +Abnormality of the spleen 33 117 2.456247441800484 0.0140396449319886 25.813106796116504 118.70145631067962 0.3588217969137363 0.458825127767632 7.787937091054707 11.816587724549532 1.4144879662363967 0.3705037351683085 4.788327882312828e-06 0.2350253809266401 0.2446636778603497 0.0008264802532387 3.477101626903786e-05 +Exaggerated startle response 3 8 2.453424150099833 0.0141503378294127 2.987864077669903 8.699029126213592 0.0610274034602423 0.2634753902852135 1.4337635656228835 1.0620090089420118 1.617556501702403 0.2831541938798349 0.0025369657709893 1.0 0.0003602808960722 0.000371706641515 0.0048822579474643 +Left ventricular hypertrophy 10 23 2.435833156038939 0.0148575357205107 7.567961165048544 23.54126213592233 0.6997255266541987 0.4097452846499351 3.537969183053948 3.034709621147107 1.2051726960058406 0.3398649994618895 0.0049659548920841 0.2731012734555347 0.1323300889211223 0.0756483536674149 0.0002997300731055 +Horizontal nystagmus 7 22 2.4263249182640387 0.0152526078430847 6.274271844660194 23.053398058252423 1.1086320165192889 0.2915732095622053 2.6115907074401723 2.1860242554539786 1.3408731048130669 0.3129960018850027 0.0013711927142081 0.2295798469686227 0.4072036678679048 0.1423397245441582 0.0042301612836837 +Urinary glycosaminoglycan excretion 4 7 2.414673830850893 0.0157493059014077 2.9490291262135924 6.563106796116505 0.4749855796693131 0.2196485727407601 1.2846457065606351 0.9261036754709504 1.6390629541794843 0.2603486997442626 0.0002281841207161 0.0697581245313758 0.0088504827764808 1.972516813028553e-05 0.0005289198821125 +Progressive neurologic deterioration 7 21 2.394614568467157 0.016637844642483 6.75 20.466019417475728 0.5813429756502071 0.2930928839947513 2.6727908035631316 1.300228015706032 1.5791549964390388 0.3142214461904322 0.0002819083381744 0.0180235679120217 0.0080456420559546 0.0036383017284534 0.0009402069411773 +Aplasia hypoplasia involving the vertebral column 9 15 2.3882202604678686 0.0169301916737811 4.679611650485437 14.847087378640778 0.8883735186508074 0.3527358077962234 2.3127489306396716 2.051146083169333 0.9597872998017484 0.2871451112966173 4.450799146958895e-05 0.187449079081247 0.0640285846884502 0.0036383017284534 2.990302515741305e-05 +Hepatosplenomegaly 14 38 2.3859486767882743 0.0170351282415095 8.516990291262136 37.93689320388349 -0.2491143078233153 0.3795771447816016 3.305218390901912 4.60907695182212 1.4437156893960243 0.3360994118928947 2.043260229072247e-05 0.3624074851394556 0.2248900268904883 0.0018302022360233 8.889504015902889e-06 +Acute coronary syndrome 6 20 2.3845034660857505 0.0171021869012142 4.315533980582524 18.70145631067961 0.2769714958633372 0.5546791842077856 2.372465731449787 1.7054162193144966 0.8386723383602402 0.2931039621058641 0.0026303379772288 0.2030241760545403 0.3655284832956332 0.0265672828357611 0.0070893533545687 +Morphological abnormality of the pyramidal tract 7 20 2.3810845210877405 0.0172617508253225 5.978155339805825 21.21359223300971 0.941567362517309 0.4190895040605777 2.5839325217273803 2.130000617333851 0.9433759961177594 0.3444076850385922 0.0949259124848601 0.2516504230112798 0.4407605172427877 0.1774767594454888 0.0698685551762488 +Abnormal vertebral morphology 29 105 2.3746709135032047 0.0175646023302327 25.18446601941747 107.1383495145631 0.7050611944944222 0.5078087978506296 8.434496402822974 10.278065304429203 1.0858158093436174 0.3796440707216367 3.804317261864715e-05 0.7901335193339849 0.3678300586898117 0.0019382116177299 0.00017335396163 +Neuronal loss in central nervous system 8 15 2.372987534424928 0.0176448594125111 4.087378640776699 12.526699029126211 0.982175765643533 0.2959736314179056 1.731247914675439 1.993135251988059 1.1236470294677874 0.2967990988512021 0.0065645821697015 0.134742527043449 0.2518545844225215 0.0352396407582777 0.0027845492980534 +Abnormal csf protein level 6 12 2.3532746052258 0.0186088857842892 4.434466019417476 12.20631067961165 1.1239853500963992 0.2260559983233297 2.11400242863219 2.084072511592451 1.241935948510828 0.248039542652958 0.0197211042902028 0.1715759324473242 0.3143397790261298 0.2436114581565515 0.0024204837857025 +Abnormal circulating cholesterol concentration 15 33 2.350127008356255 0.0187670061762568 9.691747572815531 31.70873786407767 0.976903841313624 0.2790879029908041 4.4525142732793395 3.04459115485426 1.5883623188049951 0.3063455707490317 4.2868060033552826e-05 0.3041527321586795 0.5166489093314391 0.0350926445127817 2.4429617975879658e-06 +Macroglossia 8 32 2.3469946022268484 0.0189255289530418 8.597087378640778 33.800970873786405 0.2378332400826553 0.526108686434358 3.4819634097071916 3.0993577519995683 1.045257905641647 0.335668429128709 0.0222857384693091 0.0860918177088635 0.0166529196858764 0.0118203030842149 0.0592672698942381 +Neurofibrillary tangles 4 6 2.343296673850751 0.0191141774016754 1.9878345498783456 4.347931873479319 0.5966090900062281 0.2642083372508564 1.0995898071170882 1.1496807364853057 1.4348037417662018 0.2714513638042118 0.0001573276205306 0.001984476440523 0.0002902447274798 0.0002778449152815 0.0003671727016274 +Xerostomia 6 17 2.340213948774496 0.0192726958062199 4.225728155339806 15.218446601941748 0.9400183964262208 0.3676147626670514 2.1144482637513415 1.4041718405623504 0.8665256443899695 0.3037909474394171 0.0612241796762722 0.0135379522122687 0.048990890514732 0.2256009180273313 0.0081853110588452 +Disproportionate short stature 11 24 2.336186266210209 0.0194815357708024 8.58252427184466 24.70145631067961 1.4449047806081987 0.2464238748623315 3.3320283680556178 3.793287097673045 1.0910515137563812 0.2952991105687103 0.0274577162870054 0.3498897642406863 0.0540767090111314 0.0646269414847783 0.0283278119546019 +Frontotemporal dementia 2 13 2.3353270714398096 0.0195263409981094 3.4344660194174756 10.344660194174756 0.5931524822816645 0.4529040772840182 1.8896952177098856 1.3751065734754873 0.9402199282689112 0.308701646569884 0.0862378295439867 0.0068317681715133 0.0019068669696529 0.0242110622206542 0.0351238878380088 +Abnormal morphology of the conjunctival vasculature 3 10 2.334719220423968 0.0195580935146109 2.6359223300970873 7.330097087378641 0.3791669082255805 0.3264494094231241 1.4642904354684148 1.4524057679745994 1.3542312898692437 0.2989163062985944 0.0063366759162665 0.0036723611473879 0.0007461625149634 0.0009779431698101 0.0118865434534573 +Limb ataxia 5 22 2.327288197589993 0.0199499315163467 6.597087378640777 24.114077669902912 0.989869123864314 0.3154216467413447 2.5039369509835696 2.8496458430585005 1.1323309577692284 0.292147514752726 0.0314574288370087 0.0325345581006573 0.1100932826860655 0.0138556470380734 0.0654262733188917 +Abnormal urine carbohydrate level 5 14 2.315310750306 0.0205959318513326 3.883495145631068 11.70631067961165 -0.1388020161424021 0.4168246977061866 1.9096127339504616 1.3287920569685254 1.2303643442685093 0.3136870898203888 0.0056546641425135 0.1305522111527444 0.0001585002786519 5.657491778833551e-05 0.0023211498250519 +Orthostatic hypotension 4 15 2.3050046177834003 0.021166314794633 3.6262135922330097 14.315533980582524 0.2234754096973065 0.4106322335953559 1.878879089774009 1.367959097892007 1.1506876393484995 0.291561214686976 0.004837457692714 0.1263420182810564 0.2372212797486779 0.0294507732567689 0.010278445998416 +Abnormality of head blood vessel 15 28 2.279847740361221 0.0226167204374654 7.512135922330097 24.881067961165048 0.5951213621611695 0.2501622891395578 2.541375726543966 2.628804376839775 1.8399520883426277 0.3043503409762604 5.957933032465546e-07 0.2516504230112798 0.0025924072114898 1.508991918600535e-06 1.1181812197101042e-07 +Abnormal heart sound 3 6 2.277230915389504 0.022772439908844 1.6262135922330097 5.065533980582524 0.0895700854459297 0.4481870945716114 1.1828434692827956 1.0014923118961363 1.1311355032809087 0.3141022336032418 0.0282735799915187 1.0 0.2445730022705269 0.0049571663496986 0.0498364179528963 +Delusions 5 18 2.2743712431698766 0.0229436749434037 5.912621359223301 18.439320388349515 1.0629964764413025 0.2985925736346436 2.390745896997379 2.2281751696560335 1.2165016471530676 0.297036724651636 0.0025464211549204 0.1553991536419083 0.2872333566147377 0.0097601039903573 0.0062013164624522 +Abnormality of the vasculature of the eye 21 77 2.252772211813748 0.0242735151491102 16.27912621359223 72.06553398058253 0.403343228775578 0.4479390001832676 5.629952078086087 5.671259209870798 1.3806507490937323 0.3789287537753926 0.0003739659566392 0.0235321811235652 0.0015450193882808 0.0004298223584173 0.0007007982102795 +Hypersplenism 5 9 2.2498737623935745 0.0244569599235811 2.7184466019417477 7.970873786407767 0.2142260937784027 0.1548364087136437 1.1589036979530396 1.1444786041391362 1.8316571038254568 0.2005205006822401 2.4133268249961338e-05 0.0742352733278267 0.1432798584585485 0.0561137872346343 6.703246650942136e-05 +Retinal detachment 4 19 2.24594862893186 0.0247072985507581 3.941747572815534 14.580097087378642 0.5369031517500233 0.5057677956850462 2.153458463438811 2.8955761353524423 0.8356573249695263 0.3047965741525345 0.140650865622387 1.0 1.0 0.0242455864981032 0.2339293848293204 +Hypoplastic vertebral bodies 4 6 2.235920973555381 0.0253569481882476 1.9757281553398056 5.771844660194175 0.8508946908089206 0.2775138956505893 1.1057630163966317 0.6800795892498206 1.1536023105486033 0.2559235656158802 0.0001046031266164 1.0 0.1180585699575878 0.003355333516566 0.0002457979454447 +Biliary tract abnormality 8 27 2.222035189094219 0.0262809275909696 8.184466019417476 26.4004854368932 1.3038634098573934 0.2674323053300255 3.1080777089644696 2.335313487465734 1.3483489456318312 0.3101233364725878 0.0010250492172407 0.2660187864050092 0.4620800234731917 0.2020945775525867 0.0035432778392652 +Abnormal biliary tract morphology 7 24 2.219690757201995 0.0264397666946329 7.427184466019417 23.174757281553397 1.329418499193971 0.249884151345828 2.8924137189053876 2.044064029481889 1.3393824039546371 0.2984385007787948 0.0012099624570291 0.225839943305071 0.4014202890149608 0.1367305798708485 0.00375910232126 +Supranuclear gaze palsy 6 18 2.209328960301314 0.0271517682543089 5.186893203883495 19.1626213592233 0.8242716574954257 0.3183493558985887 2.2612229396433574 2.139608194404574 1.2188387108542005 0.2935859783151378 0.0008496078188353 0.01497108596825 0.0538434207197609 0.0678108138951911 0.0004730993907641 +Parkinsonism 11 31 2.207738545992631 0.0272625041689651 7.453883495145631 30.097087378640776 0.7249761134976155 0.4663275088289313 3.116711838694066 3.708464636913605 0.8967824567735009 0.3291722600978801 0.0078463200520247 0.0080720369936571 0.0093429514575269 0.1553404749607282 0.0085630435153123 +Abnormal enchondral ossification 11 29 2.2048262867444683 0.0274662866991306 8.825242718446601 28.097087378640776 0.9354465670440578 0.4238671948965085 3.7994051258084856 4.343870948544361 0.9586864854575652 0.3408490652683477 0.0024097590606623 1.0 1.0 0.0574018644712506 0.0008638998624017 +Increased cerebral lipofuscin 4 5 2.203693904126791 0.0275458781568886 3.0970873786407767 5.118932038834951 1.0434065701738664 0.1270836154757583 1.1278862704044743 0.4599818751628888 1.7720117842909846 0.2267161680252343 2.2663533407456415e-05 0.0470522829573702 0.0039135152062846 6.292953854873037e-05 5.436360967141595e-05 +Ectopic calcification 21 60 2.199974217790156 0.0278087243056694 13.553398058252426 56.53155339805825 0.5275931647443897 0.4410566614950294 4.995100814049753 5.994858194438004 1.2985638579898735 0.3743313818119885 7.883719389655285e-06 0.1587221484945262 0.4176554250980517 6.04402342627505e-05 2.479216025371993e-06 +Progressive external ophthalmoplegia 5 8 2.1884502964224897 0.0286368180060647 3.378640776699029 10.228155339805824 0.6986896615619974 0.3934319655103426 1.8174798771838792 2.269764004486748 0.9524665755192452 0.2940766219203315 0.094236132613279 1.0 1.0 0.4846912912858679 0.0015706126808535 +Progressive psychomotor deterioration 3 8 2.1822388811828843 0.0290919071302144 3.349514563106796 8.320388349514563 0.5379615244672443 0.2176134167318772 1.5053866894387542 0.6226094824456632 1.5848775742530583 0.2457660654605461 0.0010133941165421 0.0561990347849709 0.0056684159955205 0.00262770885776 0.0019884945269669 +Hyperintensity of cerebral white matter on mri 5 20 2.1707688285151265 0.0299486513552396 5.844660194174757 19.76456310679612 0.5239793769920946 0.3497882694217939 2.383223245915457 2.1845455756818453 1.3844482033830876 0.3203944687906004 0.0090993160258402 0.1952735388158895 0.0091243340822671 0.0230341265569123 0.020723717832043 +Myoclonus 24 94 2.166096221015928 0.0303038349250339 19.92718446601942 92.40291262135922 0.7794869182612147 0.4142145469430702 6.660238401732631 11.33633180094438 1.369340457412049 0.3858779422292388 0.0311168570237082 0.3495133154240509 0.1000698604955009 0.0219601648980681 0.0066402686755561 +Amyotrophic lateral sclerosis 5 18 2.164785513393328 0.030404114724849 4.453883495145631 16.203883495145632 1.0855969203541704 0.3037117925086244 2.3812188822255287 1.5445439412417563 1.0118111691913367 0.2917679915833991 0.2303471602230429 0.0164667175849867 0.0588586045542952 0.2616785322574622 0.0469837238449897 +Central scotoma 7 10 2.151855715734968 0.0314087200332398 3.657766990291262 9.152912621359222 1.2790732929494344 0.2261272578521709 2.0233738200365714 2.077016218281829 1.2675536526802949 0.279373459017325 0.0041077133853001 0.1221118561195742 0.2297987482657219 0.1383652025719425 0.0015706126808535 +Abnormal larynx physiology 5 16 2.147645266058479 0.031741946543021 3.7694174757281553 14.78640776699029 0.7777362681295714 0.3936810823701626 2.010346212391085 1.51625807571557 0.9784109402665334 0.3028779878197117 0.1776374851388814 0.0128452267182733 0.0466281418945222 0.2166326226637888 0.0287420990175065 +Ascites 11 27 2.147474842361636 0.0317554979344321 6.538834951456311 25.800970873786408 0.2860997134153194 0.2561597752608451 2.6559964399945706 3.331112387328855 1.6846905274497244 0.2824645045304154 0.0005383957541448 1.0 1.0 0.0285848308842562 0.0001400096616651 +Abnormal thoracic spine morphology 7 26 2.142824786025649 0.0321271702683843 6.558252427184466 27.104368932038835 0.8238927765093872 0.4398474942511601 2.7009535990178555 2.5649391710658156 0.8855000478727516 0.3360788168488923 0.0033632287867975 1.0 0.4515227909961177 0.0168986737095617 0.0028431464975424 +Nasogastric tube feeding in infancy 2 7 2.127937304987828 0.0333422820546962 3.0097087378640777 8.495145631067961 1.0003947416243104 0.2675726652756056 1.510449978803449 1.1668877069106371 1.1016283190777107 0.2724768109071007 0.1110936103302734 0.1305522111527444 0.031373049189738 0.1552222190730896 0.1645088237572309 +Avascular necrosis 8 24 2.1274918357596624 0.033379238948531 5.070388349514563 21.203883495145632 0.6420454351604097 0.3947374085674277 2.2614105153836106 2.2592172512550373 1.1319127818663337 0.3183649666305153 0.0004298772769539 1.0 1.0 0.0120464435451714 0.0015622461376846 +Epiphyseal stippling 5 12 2.1217192882989964 0.033861317896044 4.638349514563107 12.094660194174756 1.0555865796987824 0.32401635996293 2.3050778042540805 1.737163917644219 0.9677864882437331 0.2966156619887163 0.0056546641425135 1.0 1.0 0.0049571663496986 0.0023211498250519 +Slurred speech 4 9 2.121330138942727 0.0338940297766565 2.45873786407767 8.864077669902912 0.5323927403653204 0.4147809462031548 1.4075891250208603 1.616351781434359 0.9973486618272436 0.2852319096618858 0.0251537295289499 1.0 0.2372212797486779 0.0294507732567689 0.010278445998416 +Decreased absent ankle reflexes 5 11 2.108224830475288 0.035011546447216 4.54126213592233 13.740291262135925 0.614698131143983 0.4646843865398717 2.302541095049457 2.6371188884218366 0.9410514279256472 0.3107404522460847 0.0251537295289499 0.1263420182810564 0.2372212797486779 0.1467432355955838 0.0446088038944012 +Abnormality of lysosomal metabolism 3 5 2.1075492366098976 0.0350699985079938 2.0509708737864076 4.776699029126213 0.6001877831871685 0.2139165882109918 1.054267347463803 0.832379194243084 1.5763659100060583 0.2506311014666729 0.0002842581971033 0.0424464003246627 0.0832836732680532 0.1981219124770219 0.0005688349419973 +Polar cataract 1 5 2.103920560760016 0.035385377126555 1.4101941747572817 3.191747572815534 1.0207696022312798 0.2606442232650584 0.8697689466453667 1.0379357100621716 1.1593360741722674 0.2587583005955745 0.0389765374255313 0.0006219606051344 0.002465796513642 0.0148625463558957 0.0542215392640632 +Psychomotor deterioration 5 9 2.096456073651692 0.0360417526591634 3.2645631067961167 8.910194174757281 0.9753014938956188 0.1960965459818884 1.3866235282600423 0.7031088807706056 1.4929387846379636 0.2609606457365817 5.737823424793828e-06 0.0607401038440192 0.0002296483500821 0.003355333516566 1.6279070379868977e-05 +Abnormality of visual evoked potentials 8 18 2.0957602470220453 0.0361034644208573 5.912621359223301 21.344660194174757 0.5310511795384435 0.4083718861321034 3.290488782756552 2.4160960308239137 1.1796429833196167 0.3304773196682204 0.0072874968128423 0.187449079081247 0.3404254693467198 0.2797556636969028 0.0168189007239576 +Increased intracranial pressure 5 20 2.09236766973354 0.0364056385728701 4.483009708737864 18.225728155339805 0.6089364319190148 0.5193135356051898 2.352895895910637 2.1988563231789326 0.7556358037224847 0.3144749703857186 0.0292170692699855 0.2443632781182481 0.4297892617739207 0.1655021226103433 0.0611543838186325 +Abnormal lower motor neuron morphology 3 10 2.090374685483724 0.0365841550528698 2.1771844660194173 8.701456310679612 0.8468629004048428 0.2893246976958152 1.3759952567341256 1.207057649999096 1.1584035743641086 0.2695692447215745 0.0785446319825815 0.1135912525516411 0.2147385524083838 0.4587195489148998 0.0308662830144804 +Thoracic kyphosis 6 16 2.081909547303188 0.0373507325580244 3.849514563106796 15.725728155339803 0.7266071624304212 0.4267138621860136 1.957478752201897 1.77496566461622 0.8648337345468261 0.3040731381323691 0.0029533055961325 1.0 0.2941077913158182 0.0107757845080475 0.0014896299843671 +Abnormal left ventricle morphology 10 27 2.079119476591896 0.0376063703656726 8.155339805825243 27.79368932038835 0.5948246759118737 0.4756129570470222 3.598158324912058 3.3281177777105677 1.054918773522773 0.3428402347836221 0.017650207478431 0.3274019772455256 0.1862598674919939 0.1374400519295191 0.0019425965813982 +Endocarditis 3 5 2.0680133246780894 0.0386387701479977 1.6699029126213591 5.055825242718447 1.0315066990472646 0.3137673633075574 1.128951309195931 0.7031759081548564 0.9300019606367588 0.2935479974969262 0.0010133941165421 1.0 1.0 0.2550529546148332 0.0019884945269669 +Echolalia 3 11 2.067186661764089 0.0387165685495667 2.9174757281553396 9.798543689320388 0.5058827478481593 0.4925214398455364 1.939118365602947 1.8645121737734769 0.8858392104742214 0.309610151743164 0.0471991190444314 0.151306852499084 0.0420348553288257 0.1988041978590851 0.0807266025333323 +Angina pectoris 3 5 2.065896545098012 0.0388382491651413 1.327669902912621 4.009708737864078 0.5754052050374406 0.3094934726297071 0.9887284212744736 0.8894761808679401 1.2599650807227574 0.2579742849945131 0.0063366759162665 0.0875404472016038 0.1677870330809631 0.0009779431698101 0.0118865434534573 +Ovoid vertebral bodies 2 8 2.0651181289571032 0.0389118244905428 2.6237864077669903 7.359223300970874 0.2693483252678329 0.2925663833748981 1.3659227234427256 1.183251804829311 1.455225024558189 0.2873440473038876 0.0510747715447815 1.0 0.1837383274168749 0.0135296171343662 0.0790607116166092 +Confusion 6 20 2.0611853332854224 0.0392853622262168 4.924757281553398 17.62378640776699 0.5770193034786405 0.489615172337713 2.480343831732211 2.1535063377225914 0.8853427180085949 0.3168581188371634 0.0026303379772288 0.2030241760545403 0.0748026769138462 0.0053616069246772 0.0070893533545687 +Chronic fatigue 3 7 2.0491644211199387 0.0404460398379911 2.0800970873786406 7.354368932038835 0.6505903571445167 0.3551914870642563 1.248646642239502 1.3902068505046723 1.081635717396615 0.2816956203568134 0.0063366759162665 0.0875404472016038 0.1677870330809631 0.0102137155300364 0.0118865434534573 +Coronal craniosynostosis 3 5 2.0379933767976808 0.0415505952440338 1.9975728155339805 5.660194174757281 0.3156922157886654 0.516342594521945 1.3247069403108018 1.1474192067777893 0.8923097804196743 0.2970323626650711 0.0051652853071714 1.0 1.0 0.357118555081159 0.0097510399506001 +Blindness 19 79 2.0356284258836133 0.0417876811630086 17.50485436893204 77.9878640776699 0.5531690923808372 0.4517712920686044 6.330499123572238 7.312865926515748 1.2869313794328858 0.374312554297374 0.0001616019725889 0.6202016441605769 0.0006412319841954 0.0032939370021869 0.000658491699027 +Abnormal pupillary function 1 6 2.032336996092376 0.0421195515743653 1.7985436893203883 6.25 0.9459174425459445 0.2892194993230557 1.1928988171245156 1.7202745886032773 1.109204161812943 0.2732247962160634 0.3593880565727997 0.1389130578490434 0.2590666885683055 0.5329697587184232 0.4482773855235765 +Fluctuations in consciousness 5 10 2.0274428340337 0.0426171451274053 2.871359223300971 7.104368932038835 1.0899440920546752 0.2545542015295898 1.680977263462837 1.481694234866534 1.1451509420956862 0.2733842157028129 0.0394770304777161 1.0 1.0 1.0 0.000200465132953 +Abnormality of epiphysis morphology 18 57 2.023673646668105 0.0430037418525757 14.885922330097088 57.24757281553398 0.6699051414631522 0.4959188251133739 5.664066249559964 8.729587504130462 1.029966158611096 0.3689041276003297 0.0007376110566052 0.6049821640239788 0.551216588314231 0.0427533229953518 0.0009678064521349 +Scotoma 8 13 2.018464145609672 0.0435429446555966 4.189320388349515 12.196601941747574 1.1271039056750725 0.2779036999445621 2.1128553643245884 2.0698220238662226 1.1901076059375446 0.2884356618441315 0.0050795814366564 0.1755724648168266 0.3209553841799009 0.0720513532108381 0.0028137185393519 +Periventricular white matter hyperintensities 3 8 2.0161424254446043 0.0437850848088636 2.978155339805826 8.604368932038835 0.7206271937008832 0.2495118997135797 1.313488091366194 1.3113693798075805 1.4898193087366574 0.2872267653893681 0.0025369657709893 0.0697581245313758 0.0088504827764808 0.0051503840765812 0.0048822579474643 +Dysgraphia 2 16 2.01601489707283 0.043798418059042 3.888349514563106 14.1747572815534 -0.020954539630261 0.7180644151789357 2.573607681679318 1.633551045654117 0.6042658996811474 0.2627585792299407 0.0950522892119901 0.0180235679120217 0.0080456420559546 0.0854582473740603 0.1542690309953486 +Abscess 2 10 2.0153266030491443 0.0438704392596196 2.808252427184466 8.75242718446602 -0.1682928545192191 0.5793581239440346 1.942031229281295 2.133156859315665 0.8090582976834073 0.2963934543352484 0.1383201070829027 1.0 1.0 0.0415700360883472 0.2015708610705285 +Aplasia hypoplasia of the femur 5 17 2.014586724702608 0.0439479695973707 4.206310679611651 14.701456310679612 0.6489043589718527 0.4831511175821769 2.1606945531522657 1.8800686352721176 0.788729448753014 0.3050726960031586 0.0029533055961325 0.1594721229818057 0.0466281418945222 0.0558093330619567 0.0071436537580251 +Diffuse white matter abnormalities 7 10 2.0074127643726083 0.0447057308131653 2.9514563106796117 8.87135922330097 0.5952845668725205 0.3852144131329246 1.9847899342355348 1.8774220853320651 1.0510828155917642 0.2960660984241839 0.0862378295439867 1.0 0.2223047329091382 0.1300982938321277 0.0074494564855197 +Abnormality of lipoprotein cholesterol concentration 7 16 2.005044633022285 0.0449582757048605 3.594660194174758 13.79126213592233 0.146670453757452 0.3159030988618912 2.0804850608489107 1.8940687593815968 1.3545369944331518 0.2589389983473483 0.0011050740067169 1.0 1.0 0.1637924032376012 6.616615234342882e-05 +Abnormal rib cage morphology 26 79 1.99804653532074 0.0457116152528038 17.694174757281555 75.7135922330097 0.5488633555797945 0.5379800174608891 5.594611229067785 9.71314341791714 0.9782995531616954 0.3690468558866111 0.0032814474502129 0.7089186794102116 0.4404840466987137 0.0202380391419625 0.0114840723707354 +Abnormal large intestine physiology 5 20 1.9968392970045503 0.045842643165421 5.104368932038835 20.50242718446602 0.3008286810865617 0.501154789704215 2.3382177969194613 2.943232146467361 0.9913296101531662 0.3267316971730095 0.0112121181580077 0.0213158974187442 0.0748026769138462 0.0053616069246772 0.0252009464097718 +Muscle stiffness 5 19 1.993117292029152 0.046248604915525 5.109223300970874 19.216019417475728 1.2530133657268057 0.2695837776665858 2.5817154639007844 2.4582801786037667 1.0397164239726309 0.2961148999712332 0.0231337505866085 0.2333020504203794 0.4129317333780675 0.1480244683995481 0.0493599670032898 +Abnormal endocardium morphology 5 14 1.992826500796682 0.0462804488130565 3.766990291262136 14.5752427184466 0.4111751310040221 0.5391262081434103 1.9531099596461143 1.4352255968673668 0.8293137150283321 0.3006328742463684 0.0064867153896704 0.1835089509173778 0.3339976348230559 0.2707185745648809 0.0150707717640174 +Toe walking 7 21 1.9879862124217755 0.0468132148569908 6.740291262135922 22.805825242718445 1.1386089770349623 0.3130572717722256 3.272869930973316 2.572476621751866 1.068544148592376 0.2998505070337083 0.0164354132133173 0.2183067054048652 0.08610744549237 0.1257511849434855 0.0029392451780606 +Capillary hemangioma 2 7 1.98798141980329 0.0468137449227212 2.533980582524272 7.133495145631068 1.1471796350867234 0.2683759543048971 1.4112277515033682 1.3471092449900268 0.9767941621718578 0.2786452679412407 0.1478553480374041 0.1471951297158956 0.0398064357050217 0.1899587232036964 0.2143350029099695 +Glomerulopathy 3 10 1.9652873114195848 0.0493809933363391 2.820388349514563 9.96359223300971 0.665958332940798 0.3017859836474246 1.512655943869742 0.8764085521210618 1.2285906000166364 0.2785070215881056 0.0127437063312673 0.1049896535105009 0.1993869387044997 0.1060727287920157 0.0233101974365333 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..8ac5a6384b9e5435a784914092ef5da381a7271b --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 4613, + "title": "Average number of proteins per term", + "value": 23.18816388467375 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f3354a5ad5a6435e9bc87b747d082ba3c03d090f --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..51f1e6ab900428f363fecb555d97c420c37ba69c --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1677 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Splenomegaly 0.5166300494290971 3.3377392849083383 0.0008446296078019 0.9797159976076556 0.7982383413766796 87 P61916,Q16625,P51798,Q99519,P07602,P15260,Q96J02,Q96A33,P54802,P04062,O15118,P04066,Q9NZ08,O00754,P15586,Q13510,P01889,P16278,P38571,Q15904,Q14108,P10253,Q96HY6,Q9NZJ7,Q14739,P21964,Q6NUQ1,P08236,P11166 29 +Mental deterioration 0.5307186172154933 3.333230038357919 0.0008584393405943 0.9809689106048936 0.7982383413766796 103 Q13501,P61916,P36543,O95470,O00592,Q9Y287,P07602,Q15526,P05067,P54802,P04062,O15118,Q8NHS3,P50897,Q92673,P03886,Q13510,P03915,P10644,P16278,P06865,P07686,P00403,Q14108,Q9H2C2,P17900,P27544,O95169,Q9NZJ7,P21964,Q9Y487,O75503,O76024,O60313,Q5XKP0,Q9BQE5 36 +Loss of speech 0.7301109980652044 3.104359164756639 0.0019069168859315 0.999850019529996 0.7982383413766796 19 O15118,P61916,Q13501,P50897,P07602,O00754,P17900 7 +Abnormal retinal artery morphology 0.7028560804707343 2.9522980100074867 0.0031541835687554 0.999999531272494 0.7982383413766796 23 P21964,P16278,P06865,P10619,P07686,Q99519,P07602,P17900,Q9Y4P3,P03886,Q13510,Q9NZJ7 12 +Dysostosis multiplex 0.9022070284730194 2.9389058147653264 0.0032937314910577 0.9999997542769872 0.7982383413766796 9 P54802,P16278,P04066,P10619,Q99519,O00754,P15586 7 +Abnormality of corneal stroma 0.7374019372707141 2.890437211072422 0.0038470637340428 0.999999981036102 0.7982383413766796 17 P04062,Q16625,P16278,P10619,P04114,P01130,O43505 7 +Corneal opacity 0.6130539855974549 2.880468152144739 0.0039708506740396 0.999999989310446 0.7982383413766796 56 O75844,Q16625,P10619,P04114,Q99519,P53701,Q9H9S5,Q9NVI7,P04062,P40855,P04066,P06280,O00754,P01130,Q13510,P16278,Q6NUK1,O43505,P08236,P51648,O95202,Q9Y4P3 22 +Chronic diarrhea 0.7140265820927372 2.8734971137877285 0.0040595478733977 0.9999999929116162 0.7982383413766796 18 P02786,Q04656,P07686,Q15904,Q96J02,Q13277,Q96A33,Q13510 8 +Abnormality of extrapyramidal motor function 0.5143607513413772 2.8683209957306772 0.0041265663248395 0.9999999948032644 0.7982383413766796 76 O75569,Q13501,O96008,O00592,P07602,Q9H6K4,Q15043,P05067,P04062,Q99720,Q92673,Q9BPX6,O14949,O75787,P16278,P06865,P07686,P17900,Q6DKK2,Q9NZJ7,P35637,P12235,P11166,Q9Y4P3 24 +Cherry red spot of the macula 0.8503722903961081 2.853448569059844 0.0043247527661678 0.9999999979250918 0.7982383413766796 10 P16278,P06865,P10619,P07686,Q99519,P07602,P17900,Q13510 8 +Arteriosclerosis 0.7071801268273213 2.8320913324087793 0.004624463755906 0.9999999994825612 0.7982383413766796 18 O75844,O15118,P61916,P16278,P38435,P04114,Q99519,P01130,Q13510 9 +Abnormality of femur morphology 0.5482648013899303 2.779341928143345 0.0054469156408094 0.999999999988576 0.7982383413766796 68 O75844,P55011,P51798,P07602,P15260,Q7LGA3,Q96A33,P04062,P04066,P06280,O95831,Q9Y619,O00754,Q9BXW9,Q9UHX1,P16278,Q04656,Q96HY6,Q9NZJ7,Q14739,Q9Y487,Q9BV10,Q6NUQ1,P16435,Q8WVQ1 25 +Oligosacchariduria 0.9303644797689646 2.770123277688588 0.0056035079692564 0.9999999999944746 0.7982383413766796 7 O00462,P16278,P04066,Q99519,P10253 5 +Bulbar signs 0.7880534185482962 2.770113524500893 0.0056036757704862 0.999999999994479 0.7982383413766796 13 P04062,Q9NZJ7,Q99720,P07602,Q15043,P03886,P03915 7 +Dementia 0.578341330717668 2.7231629248676947 0.0064660161362746 0.9999999999998992 0.7982383413766796 60 P61916,Q13501,O96008,O00592,Q9Y287,P07602,P05067,P04062,O15118,Q92673,P03886,Q13510,P03915,P06865,P00403,Q14108,P17900,P27544,Q9NZJ7,P35637,Q9Y487,O76024,O60313,P36543 24 +Cerebral inclusion bodies 0.7444858541310125 2.717100034546134 0.0065856699551538 0.9999999999999422 0.7982383413766796 15 O15118,P61916,Q9Y287,Q92673,P05067 5 +Abnormal cardiac ventricular function 0.712948285220706 2.638608557336527 0.0083247042423497 1.0 0.7982383413766796 16 O75844,P12235,P09622,P04114,P03886,Q9H9S5,P01130,P10253,P03915 9 +Abnormal tissue metabolite concentration 0.7263211205610608 2.6157087161023544 0.0089042482520631 1.0 0.7982383413766796 15 P40855,P06865,P06280,P07686,P07602,P17900 6 +Abnormal macrophage morphology 0.8939592908732729 2.6124494793655915 0.0089895977683476 1.0 0.7982383413766796 7 O15118,P61916,P16278,Q99519,P15260,Q13510 6 +Osteoarthritis 0.7834074657369359 2.594861656646929 0.0094628999384274 1.0 0.7982383413766796 11 P04062,O75844,P01889,P51798,Q14108,Q8WVQ1 6 +Coxa valga 0.6465527461590141 2.578870229464744 0.0099124016433858 1.0 0.7982383413766796 19 O75844,P16278,P04066,Q04656,Q9Y619,O00754,Q8WVQ1,Q96A33 8 +Abnormal form of the vertebral bodies 0.4462802081284696 2.5665271439900827 0.0102722585076355 1.0 0.7982383413766796 83 P51798,Q99519,Q96J02,P54802,P04066,O95831,Q8TAA9,Q9Y619,O00754,P15586,P10644,Q9UHX1,P16278,Q04656,Q6NUK1,Q96HY6,Q14739,Q9BV10,Q6NUQ1,P08236,P16435,Q8WVQ1,O95202,Q9Y4P3 24 +Abnormality of alkaline phosphatase level 0.640927348584508 2.5499041594704623 0.0107752536172458 1.0 0.7982383413766796 23 Q13501,Q96JJ3,P38571,P51798,Q8N511,Q92643,Q96A33 7 +Diarrhea 0.488079313423744 2.531459101988478 0.0113589063246795 1.0 0.7982383413766796 75 P39210,O00592,P15260,Q96J02,Q13277,Q96A33,P54802,P02786,P06280,Q5HYI8,Q86UE8,Q9Y6B6,P15586,P03886,Q13510,P01889,Q13423,P38571,Q04656,P07686,Q15904,P42892 22 +Clumsiness 0.6584038442117446 2.5309626916897523 0.0113749947035275 1.0 0.7982383413766796 18 Q13501,O75503,O14773,P07602,O00754,Q13510 6 +Abnormality of glycolipid metabolism 0.8705274315251416 2.5093130774636907 0.0120966218458944 1.0 0.7982383413766796 7 P06865,P06280,P07686,P07602,P17900 5 +Abnormal epiphyseal ossification 0.6716920702692337 2.499748318144785 0.0124281565381862 1.0 0.7982383413766796 17 P10644,Q14739,P40855,Q9UG56,P38435,P08236,Q99519,Q96HY6 8 +Foam cells 0.8936659008861194 2.4988841536368662 0.0124585030366954 1.0 0.7982383413766796 6 O15118,P61916,P16278,Q99519,Q13510 5 +Shoulder girdle muscle weakness 0.7725740599000183 2.476660795672654 0.01326178730194 1.0 0.7982383413766796 10 P12235,P07602,Q9H9S5,Q9NZJ7 4 +Abnormality of the spleen 0.4667304661943508 2.4562474418004836 0.0140396449319886 1.0 0.7982383413766796 117 P61916,Q16625,P10619,P51798,Q99519,P07602,P15260,Q96J02,Q96A33,P54802,P04062,O15118,P04066,Q5HYI8,Q9NZ08,O00754,P15586,Q13510,P01889,P16278,P38571,P07686,Q15904,Q14108,P10253,Q96HY6,Q9NZJ7,Q14739,P21964,Q6NUQ1,P08236,P11166,O95202 33 +Exaggerated startle response 0.827756827622884 2.453424150099833 0.0141503378294127 1.0 0.7982383413766796 8 P16278,P06865,P17900 3 +Left ventricular hypertrophy 0.6238986419905923 2.435833156038939 0.0148575357205107 1.0 0.7982383413766796 23 O75787,P12235,Q07021,P06280,Q6NUK1,P00533,P10253,P03886,Q9H9S5,P03915 10 +Horizontal nystagmus 0.6228258029543359 2.4263249182640387 0.0152526078430847 1.0 0.7982383413766796 22 P04062,O95831,O14773,Q9H061,P07602,O60313,Q9NZJ7 7 +Urinary glycosaminoglycan excretion 0.8492849272387561 2.4146738308508935 0.0157493059014077 1.0 0.7982383413766796 7 P54802,P04066,P16278,P15586 4 +Progressive neurologic deterioration 0.6183275875183115 2.394614568467157 0.016637844642483 1.0 0.7982383413766796 21 P54802,P04062,P16278,P07686,Q9Y287,P07602,Q5XKP0 7 +Aplasia hypoplasia involving the vertebral column 0.6863737812958823 2.3882202604678686 0.0169301916737811 1.0 0.7982383413766796 15 P10644,Q14739,P16278,P04066,Q6NUQ1,O95831,P08236,Q8TAA9,Q96HY6 9 +Hepatosplenomegaly 0.6007475929836249 2.3859486767882743 0.0170351282415095 1.0 0.7982383413766796 38 P04062,P16278,P38571,P51798,P10619,P07686,Q5HYI8,Q99519,P11166,P15260,O00754,Q96J02,Q96HY6,Q13510 14 +Acute coronary syndrome 0.6169331930356132 2.3845034660857505 0.0171021869012142 1.0 0.7982383413766796 20 O75844,P01889,P06280,P04114,Q9NZ08,P01130 6 +Morphological abnormality of the pyramidal tract 0.6164211658767178 2.3810845210877405 0.0172617508253225 1.0 0.7982383413766796 20 Q13501,P35637,O00400,O95831,P11166,Q9Y619,Q9Y4P3 7 +Abnormal vertebral morphology 0.4499738977645009 2.3746709135032047 0.0175646023302327 1.0 0.7982383413766796 105 P10619,P51798,Q99519,Q96J02,Q9H9S5,P54802,P04062,P04066,O95831,Q8TAA9,Q9Y619,O00754,P15586,P10644,Q9UHX1,P16278,Q5SZK8,Q04656,Q6NUK1,Q14108,Q96HY6,Q14739,Q9BV10,Q6NUQ1,P08236,P16435,Q8WVQ1,O95202,Q9Y4P3 29 +Neuronal loss in central nervous system 0.6837379424641786 2.3729875344249276 0.0176448594125111 1.0 0.7982383413766796 15 P04062,O15118,P35637,Q9BTW9,Q6PJG6,P07602,Q92581,Q9NZJ7 8 +Abnormal csf protein level 0.7232269158174787 2.3532746052257996 0.0186088857842892 1.0 0.7982383413766796 12 P55011,Q16625,Q9NZJ7,P07602,P03886,P03915 6 +Abnormal circulating cholesterol concentration 0.6033643866788139 2.350127008356255 0.0187670061762568 1.0 0.7982383413766796 33 Q9NVI7,Q14739,P61916,Q9BV10,P38571,Q15800,Q8N511,Q10471,Q15904,P04114,P07602,Q9Y6B6,P01130,P50402,Q9NZJ7 15 +Macroglossia 0.6041348282568082 2.3469946022268484 0.0189255289530418 1.0 0.7982383413766796 32 P16278,P04066,P07686,P10253,Q9H9S5,O00754,Q7LGA3,Q96A33 8 +Neurofibrillary tangles 0.8579035166163693 2.343296673850751 0.0191141774016754 1.0 0.7982383413766796 6 P05067,O15118,Q9Y287,Q92673 4 +Xerostomia 0.6457355938473732 2.3402139487744957 0.0192726958062199 1.0 0.7982383413766796 17 Q14739,P35637,Q13501,P55011,Q15165,Q68CQ7 6 +Disproportionate short stature 0.6088488504435285 2.3361862662102095 0.0194815357708024 1.0 0.7982383413766796 24 Q15392,P10644,Q14739,Q9UHX1,Q9BV10,P16278,Q7RTS9,P42345,Q8WVQ1,Q7LGA3,Q96HY6 11 +Frontotemporal dementia 0.7064285118870941 2.3353270714398096 0.0195263409981094 1.0 0.7982383413766796 13 Q13501,P05067 2 +Abnormal morphology of the conjunctival vasculature 0.7442123938687565 2.3347192204239677 0.0195580935146109 1.0 0.7982383413766796 10 O00462,P04066,P06280 3 +Limb ataxia 0.608159686302292 2.3272881975899935 0.0199499315163467 1.0 0.7982383413766796 22 Q13501,Q8IV08,O14773,Q14108,O00754 5 +Abnormal urine carbohydrate level 0.6886766597507528 2.315310750306 0.0205959318513326 1.0 0.7982383413766796 14 O00462,P16278,P04066,Q99519,P10253 5 +Orthostatic hypotension 0.6720327184396581 2.3050046177834003 0.021166314794633 1.0 0.7982383413766796 15 P04062,Q04656,P07602,P07686 4 +Angiokeratoma 0.9691702197441772 2.289084053533174 0.0220744691610341 1.0 0.7982383413766796 4 P16278,P04066,P06280 3 +Abnormality of head blood vessel 0.5984841808701774 2.279847740361221 0.0226167204374654 1.0 0.7982383413766796 28 P21964,Q9NZJ7,P16278,P06865,P10619,P07686,P04114,P01130,Q99519,P07602,P17900,Q9Y4P3,P03886,Q13510,P03915 15 +Abnormal heart sound 0.842917279593852 2.277230915389504 0.022772439908844 1.0 0.7982383413766796 6 P04114,P01130,P10253 3 +Delusions 0.6182021843931285 2.2743712431698766 0.0229436749434037 1.0 0.7982383413766796 18 P04062,P21964,P07602,O00754,Q9BQE5 5 +Abnormality of the vasculature of the eye 0.4525035961019896 2.252772211813748 0.0242735151491102 1.0 0.7982383413766796 77 P10619,Q99519,P07602,P02786,P04066,P06280,Q9NZ08,P03886,Q13510,P01889,P16278,P06865,P07686,P17900,Q9NZJ7,O00462,Q14739,P21964,P04439,Q15555,P38435 21 +Hypersplenism 0.7557855615983069 2.2498737623935745 0.0244569599235811 1.0 0.7982383413766796 9 P04062,P38571,P07602,Q14108,Q96J02 5 +Retinal detachment 0.5962577060634375 2.2459486289318593 0.0247072985507581 1.0 0.7982383413766796 19 P04439,O43505,P98164,Q9H9S5 4 +Hypoplastic vertebral bodies 0.8336054522433136 2.235920973555381 0.0253569481882476 1.0 0.7982383413766796 6 P10644,P16278,Q14739,Q8TAA9 4 +Biliary tract abnormality 0.5909625258163997 2.222035189094219 0.0262809275909696 1.0 0.7982383413766796 27 P04062,P09601,Q14108,P07602,Q96J02,O95202,Q5XKP0,Q9NZJ7 8 +Abnormal biliary tract morphology 0.591977470300442 2.219690757201995 0.0264397666946329 1.0 0.7982383413766796 24 P04062,P09601,Q14108,P07602,Q96J02,Q5XKP0,Q9NZJ7 7 +Supranuclear gaze palsy 0.6082020014796042 2.209328960301314 0.0271517682543089 1.0 0.7982383413766796 18 P04062,O15118,P61916,Q13501,Q99720,P07602 6 +Parkinsonism 0.5859034741066319 2.207738545992631 0.0272625041689651 1.0 0.7982383413766796 31 P04062,O75569,Q13501,O75787,P35637,Q99720,P07602,Q92673,Q15043,P05067,Q9NZJ7 11 +Abnormal enchondral ossification 0.5871987542331808 2.2048262867444683 0.0274662866991306 1.0 0.7982383413766796 29 P10644,Q14739,P40855,Q9UG56,P38435,P08236,Q99519,Q9Y619,Q8WVQ1,O95202,Q96HY6 11 +Increased cerebral lipofuscin 0.8861548556430369 2.203693904126791 0.0275458781568886 1.0 0.7982383413766796 5 O75503,O14773,P07602,P50897 4 +Ectopic calcification 0.5200926002168313 2.1999742177901553 0.0278087243056694 1.0 0.7982383413766796 60 O75844,Q16625,P04114,Q99519,P05067,P04062,P40855,O00584,P53634,P03886,P01130,P03915,P10644,P38571,Q04656,P23786,Q14739,P38435,P08236,P11166,O60313 21 +Progressive external ophthalmoplegia 0.7713215281215454 2.1884502964224897 0.0286368180060647 1.0 0.7982383413766796 8 P12235,Q07021,O60313,P03886,P03915 5 +Progressive psychomotor deterioration 0.7700199849413886 2.1822388811828843 0.0290919071302144 1.0 0.7982383413766796 8 P16278,P07602,P07686 3 +Vacuolated lymphocytes 0.9412922269596552 2.1794907018881817 0.0292952346560511 1.0 0.7982383413766796 4 P16278,P04066,Q99519 3 +Thickened ribs 0.9406362741882556 2.1768968452291046 0.0294882648735894 1.0 0.7982383413766796 4 P16278,O00754,P54802 3 +Hyperintensity of cerebral white matter on mri 0.585309790963662 2.1707688285151265 0.0299486513552396 1.0 0.7982383413766796 20 O75503,P07602,P17900,P10253,Q9NZJ7 5 +Myoclonus 0.4235576404313567 2.166096221015928 0.0303038349250339 1.0 0.7982383413766796 94 O96008,Q96CU9,O00592,Q99519,P07602,P05067,P04062,P50897,Q92673,Q01105,P03886,Q13510,P03915,P00403,Q14108,Q9H2C2,P27544,Q9NZJ7,P00374,O75503,Q9UBX3,O14773,P11166,P13073 24 +Amyotrophic lateral sclerosis 0.6013965402093541 2.164785513393328 0.030404114724849 1.0 0.7982383413766796 18 Q13501,P35637,Q15165,Q99720,Q68CQ7 5 +Central scotoma 0.708399334936522 2.1518557157349676 0.0314087200332398 1.0 0.7982383413766796 10 Q8NHS3,Q9Y287,Q9H061,O60313,Q9H6K4,P03886,P03915 7 +Abnormal larynx physiology 0.630550601527475 2.147645266058479 0.031741946543021 1.0 0.7982383413766796 16 Q13501,P35637,Q15165,Q68CQ7,Q13510 5 +Ascites 0.5804585894997555 2.147474842361636 0.0317554979344321 1.0 0.7982383413766796 27 P10644,P04062,Q14739,O15118,P61916,O75787,P38571,P08236,Q99519,Q14108,Q13510 11 +Abnormal thoracic spine morphology 0.580284087167649 2.1428247860256495 0.0321271702683843 1.0 0.7982383413766796 26 P04062,O75844,Q9UHX1,P08236,O00754,P51648,Q96J02 7 +Nasogastric tube feeding in infancy 0.7863772296060677 2.127937304987828 0.0333422820546962 1.0 0.7982383413766796 7 P07602,Q9UHX1 2 +Avascular necrosis 0.5787809758553497 2.1274918357596624 0.033379238948531 1.0 0.7982383413766796 24 P04062,O75844,Q04656,P51798,Q9NZ08,Q9Y619,Q14108,O00754 8 +Epiphyseal stippling 0.6802120465358632 2.1217192882989964 0.033861317896044 1.0 0.7982383413766796 12 P10644,P40855,P38435,P08236,Q99519 5 +Slurred speech 0.7298215920823063 2.121330138942727 0.0338940297766565 1.0 0.7982383413766796 9 P16278,O00592,Q99519,O75787 4 +Decreased absent ankle reflexes 0.6892395852141336 2.108224830475288 0.035011546447216 1.0 0.7982383413766796 11 P12235,Q13501,O75787,O60313,P07196 5 +Abnormality of lysosomal metabolism 0.8633336530886874 2.1075492366098976 0.0350699985079938 1.0 0.7982383413766796 5 P07602,P51798,Q13510 3 +Polar cataract 0.8624769558695676 2.103920560760016 0.035385377126555 1.0 0.7982383413766796 5 Q9Y287 1 +Psychomotor deterioration 0.7248430072916434 2.096456073651692 0.0360417526591634 1.0 0.7982383413766796 9 Q9Y487,P06865,P50897,P07602,Q9NZJ7 5 +Abnormality of visual evoked potentials 0.590918612610591 2.0957602470220453 0.0361034644208573 1.0 0.7982383413766796 18 Q15042,Q8TC12,O75503,Q15067,P51798,P07602,O60313,Q9NZJ7 8 +Increased intracranial pressure 0.5739014823605151 2.0923676697335396 0.0364056385728701 1.0 0.7982383413766796 20 P10644,P01889,Q96JJ3,Q9NZ08,P07602 5 +Abnormal lower motor neuron morphology 0.6965356234609018 2.090374685483724 0.0365841550528698 1.0 0.7982383413766796 10 Q99720,Q13501,Q13510 3 +Thoracic kyphosis 0.6198749648489469 2.081909547303188 0.0373507325580244 1.0 0.7982383413766796 16 P04062,Q9UHX1,O95831,P08236,P51648,O00754 6 +Abnormal left ventricle morphology 0.5709043582683966 2.079119476591896 0.0376063703656726 1.0 0.7982383413766796 27 O75787,P12235,Q07021,P06280,Q6NUK1,P00533,P10253,P03886,Q9H9S5,P03915 10 +Endocarditis 0.8540173223080607 2.0680133246780894 0.0386387701479977 1.0 0.7982383413766796 5 P10644,P04062,Q9NZ08 3 +Echolalia 0.681549517657855 2.067186661764089 0.0387165685495667 1.0 0.7982383413766796 11 P53701,Q13501,Q9UHX1 3 +Angina pectoris 0.8535196145781652 2.065896545098012 0.0388382491651413 1.0 0.7982383413766796 5 P04114,O75844,P06280 3 +Ovoid vertebral bodies 0.7456545829025897 2.0651181289571032 0.0389118244905428 1.0 0.7982383413766796 8 P54802,P16278 2 +Confusion 0.5693917669896784 2.0611853332854224 0.0392853622262168 1.0 0.7982383413766796 20 Q9NZ08,P11166,Q9Y619,O00754,Q92673,P05067 6 +Chronic fatigue 0.7694601574269975 2.0491644211199387 0.0404460398379911 1.0 0.7982383413766796 7 Q5HYI8,P07602,Q13423 3 +Coronal craniosynostosis 0.846969167646754 2.0379933767976808 0.0415505952440338 1.0 0.7982383413766796 5 P16435,Q6NUK1,Q9NX62 3 +Blindness 0.4238503867733489 2.0356284258836133 0.0417876811630086 1.0 0.7982383413766796 79 P51798,Q9Y6M9,P07602,P53701,Q9H9S5,Q8NHS3,Q9NZ08,P50897,P03886,P01889,P16278,P06865,Q5SZK8,P07686,Q86Y39,O43676,P17900,O43505,Q15555 19 +Abnormal pupillary function 0.7883535078710663 2.0323369960923756 0.0421195515743653 1.0 0.7982383413766796 6 P07602 1 +Fluctuations in consciousness 0.6844812795470098 2.0274428340336996 0.0426171451274053 1.0 0.7982383413766796 10 P04062,P00403,Q15526,P03886,P03915 5 +Abnormality of epiphysis morphology 0.5107243550646048 2.023673646668105 0.0430037418525757 1.0 0.7982383413766796 57 Q9HC07,P10644,Q14739,P40855,P16278,Q9UG56,Q04656,P51798,Q6NUQ1,P38435,O95831,P08236,Q99519,Q9Y619,Q8WVQ1,Q7LGA3,O95202,Q96HY6 18 +Scotoma 0.6495945708792639 2.018464145609672 0.0435429446555966 1.0 0.7982383413766796 13 Q8NHS3,P04439,Q9H061,O60313,Q9Y287,Q9H6K4,P03886,P03915 8 +Periventricular white matter hyperintensities 0.7355629808088302 2.0161424254446043 0.0437850848088636 1.0 0.7982383413766796 8 O75503,P17900,P07602 3 +Dysgraphia 0.6092531275759778 2.01601489707283 0.043798418059042 1.0 0.7982383413766796 16 Q13501,P05067 2 +Abscess 0.682170670414189 2.0153266030491443 0.0438704392596196 1.0 0.7982383413766796 10 Q5HYI8,P53634 2 +Aplasia hypoplasia of the femur 0.5942336817346394 2.014586724702608 0.0439479695973707 1.0 0.7982383413766796 17 Q9UHX1,Q9BV10,O95831,P15260,Q8WVQ1 5 +Diffuse white matter abnormalities 0.6806632334216463 2.0074127643726083 0.0447057308131653 1.0 0.7982383413766796 10 P16278,O43819,Q3ZCQ8,Q9Y5P6,Q15526,Q9H9S5,O95169 7 +Abnormality of lipoprotein cholesterol concentration 0.6074923939122813 2.0050446330222855 0.0449582757048605 1.0 0.7982383413766796 16 P38571,Q15800,Q8N511,Q10471,P04114,Q9Y6B6,P01130 7 +Abnormal rib cage morphology 0.4207091667678189 1.99804653532074 0.0457116152528038 1.0 0.7982383413766796 79 O75844,P51798,P07237,P54802,P17612,P04066,P08069,O95831,Q8TAA9,Q9Y619,O00754,P15586,O75419,Q9UHX1,P16278,Q04656,Q7RTS9,Q96HY6,Q14739,Q9BV10,O60826,P08236,P16435,P48651,Q8WVQ1,O95202 26 +Abnormal large intestine physiology 0.5601346200813977 1.9968392970045503 0.045842643165421 1.0 0.7982383413766796 20 P21964,P06280,Q8TAA9,P07602,Q92581 5 +Muscle stiffness 0.5593293179233743 1.993117292029152 0.046248604915525 1.0 0.7982383413766796 19 O00592,P11166,P07602,P23786,P46020 5 +Abnormal endocardium morphology 0.6326499531749368 1.992826500796682 0.0462804488130565 1.0 0.7982383413766796 14 P10644,P04062,P01889,P06280,Q9NZ08 5 +Toe walking 0.5590512650115464 1.9879862124217755 0.0468132148569908 1.0 0.7982383413766796 21 P50402,Q99720,O95831,P07602,Q86UE8,Q9H9S5,Q9NZJ7 7 +Capillary hemangioma 0.756423681982656 1.98798141980329 0.0468137449227212 1.0 0.7982383413766796 7 Q7LGA3,Q9UHX1 2 +Bone marrow foam cells 0.8930796982617203 1.9870148230669251 0.0469207542234997 1.0 0.7982383413766796 4 Q99519,O15118,P61916 3 +Glomerulopathy 0.6726623514939102 1.9652873114195852 0.0493809933363391 1.0 0.7982383413766796 10 Q14108,Q9NZ08,P06280 3 +Erlenmeyer flask deformity of the femurs 0.885864217776311 1.9578963231236584 0.0502421794489804 1.0 0.7982383413766796 4 P04062,P51798,P07602 3 +Airway obstruction 0.6131129618821367 1.954341361756445 0.0506608603880003 1.0 0.7982383413766796 15 O75844,P21964,P09601,P06280,Q96HY6 5 +Abnormal larynx morphology 0.5526848389427649 1.9473514820040423 0.0514926105508473 1.0 0.7982383413766796 27 Q14739,P21964,Q9UHX1,Q5SZK8,P16435,P07602,Q96HY6,Q13510,Q9NZJ7 9 +Underdeveloped supraorbital ridges 0.6585985538453737 1.9435307073057584 0.0519520689012034 1.0 0.7982383413766796 11 O75381,P40855,Q6NUK1,P50542,P16435,Q99519,Q08J23 7 +Episodic vomiting 0.6683578199690695 1.9425387648335544 0.0520719118208359 1.0 0.7982383413766796 10 P00403,Q9Y619,Q2TAA5,P03886,P03915 5 +Hypocholesterolemia 0.693543982216185 1.9384157419149204 0.0525725213989702 1.0 0.7982383413766796 9 Q9NVI7,Q9BV10,P07602,Q9Y6B6,Q9NZJ7 5 +Hemiparesis 0.5514106614128925 1.9379682971050092 0.0526270904951462 1.0 0.7982383413766796 19 P01889,P42345,P00403,Q9NZ08,P11166,P49815,O60313,P03886,P03915 9 +Abnormal chorioretinal morphology 0.5511689078688831 1.931501553221204 0.0534210574239566 1.0 0.7982383413766796 24 P04439,Q9Y619,P53701,Q5XKP0,O43505,Q9H9S5 6 +Abnormality of the distal phalanges of the toes 0.7658681270453138 1.9294417579348624 0.0536760439243637 1.0 0.7982383413766796 6 Q7LGA3,O75844 2 +Occipital encephalocele 0.7657898509045737 1.9290815727125008 0.0537207362491165 1.0 0.7982383413766796 6 O43505,Q9H9S5 2 +Widened cerebral subarachnoid space 0.8213462733030684 1.928073671614356 0.0538459632712362 1.0 0.7982383413766796 5 P03915,P03886,Q9BV10 3 +Abdominal distention 0.5500695499830988 1.924740610875969 0.0542618171588311 1.0 0.7982383413766796 21 P04062,P38571,Q5SZK8,Q01844,P07602,Q9Y6B6,Q13277,Q96HY6,Q9NZJ7 9 +Fatigable weakness of swallowing muscles 0.6066255601494922 1.9148653887686768 0.0555096727902253 1.0 0.7982383413766796 15 Q15165,Q13501,P35637,Q68CQ7 4 +Sensorimotor neuropathy 0.5462588705010021 1.9107099687233795 0.0560418630222436 1.0 0.7982383413766796 30 Q9NZJ7,P39210,P05023,P00403,O95831,P07602,O60313,Q5KU26,Q9Y2R0,P03886,P03915 11 +Chorioretinal dysplasia 0.8168894173002215 1.9088302620650168 0.0562839916491559 1.0 0.7982383413766796 5 O43505,Q9H9S5 2 +Abnormal autonomic nervous system physiology 0.5433978758175636 1.9056604187329629 0.056694277781871 1.0 0.7982383413766796 33 P04062,P42892,Q04656,P06280,P07686,O00592,P07602,P0DP25,Q9NZJ7 9 +Depression 0.4086301754236495 1.9010488677945736 0.0572956120887455 1.0 0.7982383413766796 101 Q13501,Q96N66,P55011,O00592,P07602,P04062,P06280,Q68CQ7,P50897,O00754,P03886,P03915,P10644,P01889,P00403,Q6DKK2,Q9NZJ7,P12235,P21964,P35637,Q96C86,Q15165,O76024,P11166,Q9NZ01,Q9Y4P3 26 +Long toe 0.7116889613752371 1.8991973188607676 0.0575385371399783 1.0 0.7982383413766796 8 P10644,Q9UHX1 2 +Ventricular preexcitation 0.7586586092676305 1.896210123236138 0.0579322651008424 1.0 0.7982383413766796 6 P03915,P03886,P10253,P00403 4 +Mucosal telangiectasiae 0.6488000524697829 1.8902026432360168 0.0587308633219005 1.0 0.7982383413766796 11 Q8IZA0,P06280,P10619 3 +Undetectable electroretinogram 0.8122389543839514 1.8887123965430697 0.0589303766369913 1.0 0.7982383413766796 5 P50897 1 +Abnormal femoral neck head morphology 0.5228085333882567 1.8883007388874289 0.0589855881890795 1.0 0.7982383413766796 46 O75844,Q14739,Q9Y487,P16278,P04066,Q04656,Q6NUQ1,O95831,Q9Y619,P15260,O00754,Q7LGA3,Q8WVQ1,Q96HY6,Q96A33 15 +Anophthalmia 0.6375375474145132 1.8856005780572944 0.0593487994490633 1.0 0.7982383413766796 12 Q5SZK8,O43505,Q9H9S5 3 +Weak voice 0.7559357540985813 1.8836293566511015 0.0596151280546402 1.0 0.7982383413766796 6 P04062,O00592 2 +Vertebral hypoplasia 0.657192416880986 1.8832566208668955 0.0596655990959027 1.0 0.7982383413766796 10 P10644,Q14739,P16278,Q8TAA9,Q96HY6 5 +Disproportionate short limb short stature 0.5434190976193032 1.879504345337096 0.0601756607551939 1.0 0.7982383413766796 20 Q15392,P10644,Q14739,Q9BV10,Q7RTS9,P42345,Q8WVQ1,Q7LGA3 8 +Progressive spastic quadriplegia 0.7064989119360041 1.8735747315188287 0.0609890635163594 1.0 0.7982383413766796 8 P17900,P07602 2 +Amyloidosis 0.9724981394773222 1.871889368890542 0.0612219106844587 1.0 0.7982383413766796 3 Q9Y287 1 +Retinopathy 0.5413328821688751 1.8700673240713177 0.061474469380983 1.0 0.7982383413766796 29 P01889,Q8NHS3,Q15555,Q9NZ08,Q99519,P51648,Q15526,Q9Y6B6,O95202 9 +Hepatitis 0.5571296204823941 1.869499275815744 0.0615533842969227 1.0 0.7982383413766796 18 P08236,Q04656,Q9Y619,P11717 4 +Abnormal muscle fiber morphology 0.4643297233148159 1.8673892528911349 0.0618472495137718 1.0 0.7982383413766796 66 Q13501,Q70HW3,Q15526,Q9H9S5,P05067,Q99720,O95831,Q92673,Q9BPX6,P03886,P03915,O14979,P00403,O43676,P23786,Q9H2D1,P50402,P35637,P12235,O60313,P07196 21 +Hypomimic face 0.6438850017523731 1.8633327924406429 0.062415459211699 1.0 0.7982383413766796 11 P04062,O00592,P12235,O75787 4 +Increased bone mineral density 0.5409780260856023 1.8581196009668797 0.0631520319257568 1.0 0.7982383413766796 24 P54802,P04062,Q14739,Q13501,P51798,P48651,Q14108,Q15043,Q9Y4P3 9 +Heparan sulfate excretion in urine 0.8606793885808572 1.8556491870619 0.0635035778770833 1.0 0.7982383413766796 4 P54802,P15586 2 +Orthostatic hypotension due to autonomic dysfunction 0.6763856401903845 1.850566935369509 0.0642318801794517 1.0 0.7982383413766796 9 P04062,P07602 2 +Aplasia hypoplasia involving the pelvis 0.5956510722033443 1.847697782841456 0.0646460749051549 1.0 0.7982383413766796 15 O95831,O95202,P15260,Q8WVQ1 4 +Fatigable weakness of bulbar muscles 0.5683689755957444 1.84645864006538 0.0648256394908244 1.0 0.7982383413766796 17 Q15165,Q13501,P35637,Q68CQ7 4 +Osteomyelitis 0.5536624277693615 1.8459671937430473 0.0648969690150347 1.0 0.7982383413766796 18 P39210,Q6DD88,Q04656,P51798,P15260,O15269 6 +Elevated serum acid phosphatase 0.8581735644926851 1.845425051425564 0.0649757317622274 1.0 0.7982383413766796 4 P51798,P07602 2 +Sepsis 0.5381212524986969 1.8420103660664529 0.065473633603166 1.0 0.7982383413766796 20 P42892,P01889,P02786,Q9BV10,Q04656 5 +Gait ataxia 0.4613159725728071 1.836575794908207 0.0662725433283519 1.0 0.7982383413766796 66 Q13501,Q8IV08,O00592,P07602,Q9NVI7,O15118,P98155,O00754,Q9UID3,P03886,P03915,P04350,Q14108,Q92581,Q9NZJ7,P12235,O43292,O14773,P07196 19 +Joint subluxation 0.7450355945002602 1.833102651194944 0.0667873069363411 1.0 0.7982383413766796 6 Q9UHX1 1 +Vascular tortuosity 0.8543784847490867 1.829923488712946 0.0672613805661659 1.0 0.7982383413766796 4 Q04656,P03886,P05067 3 +Decerebrate rigidity 0.8539823358322176 1.8283041818533283 0.0675039125671892 1.0 0.7982383413766796 4 P16278,P07602 2 +Macular purpura 0.5784476511184842 1.8221559619324128 0.0684313244518797 1.0 0.7982383413766796 16 P10644,Q16625,P51798,P38435,Q99519 5 +Abnormality of the pubic bone 0.6954617768312142 1.8188519909605312 0.0689340139525931 1.0 0.7982383413766796 8 Q8IZA0,O95202,Q5SZK8,Q04656 4 +Hypoplasia of the iris 0.6692592024653483 1.813831885930416 0.0697036118579863 1.0 0.7982383413766796 9 Q7LGA3,P98164 2 +Psoriasiform dermatitis 0.8504427681206873 1.8138259548320113 0.0697045252687404 1.0 0.7982383413766796 4 P01889,P10321,P00533 3 +Motor neuron atrophy 0.5343286963577337 1.8099384742374724 0.0703053288552095 1.0 0.7982383413766796 24 Q13501,P35637,Q15165,Q99720,Q68CQ7,Q16637,Q13510 7 +Pulmonary infiltrates 0.6433561663640723 1.8092462060778551 0.0704127621206767 1.0 0.7982383413766796 10 Q13510,P04062,Q9NZ08,P15260 4 +Abnormality of the biliary system 0.40629800775862 1.8065389217088543 0.070834200221622 1.0 0.7982383413766796 107 P61916,Q16625,P09601,P39210,P07602,Q96J02,Q96A33,P04062,O15118,P40855,P04066,Q5HYI8,Q13510,P10644,O75787,P38571,Q04656,Q15904,Q14108,Q9NZJ7,Q14739,P21964,Q6NUQ1,P11166,O95202,Q5XKP0 26 +Abnormality of the tongue 0.3896738368333139 1.8017856249353548 0.0715791402600829 1.0 0.7982383413766796 88 O75844,P40855,P01889,Q15042,P16278,Q5SZK8,P04066,Q6NUK1,P07686,O95831,Q99519,Q9H9S5,O00754,Q7LGA3,Q96A33,P10253,Q13510 17 +Peripheral opacification of the cornea 0.8454608707978024 1.7934183869006046 0.072906049710598 1.0 0.7982383413766796 4 P04114 1 +Abnormal upper motor neuron morphology 0.6401880226810052 1.7922152276372303 0.073098496332107 1.0 0.7982383413766796 10 Q99720,Q13501 2 +Abnormal femoral head morphology 0.5316652587767718 1.791031982135789 0.0732881628900823 1.0 0.7982383413766796 23 P16278,Q04656,Q6NUQ1,O95831,P15260,Q8WVQ1,Q7LGA3 7 +Unilateral renal agenesis 0.5453672060113659 1.7894325773287532 0.0735451767255865 1.0 0.7982383413766796 18 P10644,Q7LGA3,Q86XL3,Q9UHX1 4 +Congenital hypothyroidism 0.8434574839350351 1.7852021575765364 0.0742285321402493 1.0 0.7982383413766796 4 P10644 1 +Abnormal ldl cholesterol concentration 0.585015509240115 1.7821439556707213 0.0747257593682235 1.0 0.7982383413766796 15 P38571,Q15800,Q8N511,P04114,Q9Y6B6,P01130 6 +Abnormal circulating lipid concentration 0.4371826234793061 1.7815167291264309 0.0748280744192499 1.0 0.7982383413766796 71 O75844,P61916,Q8N511,O95470,P04114,P07602,Q9NVI7,P40855,P06280,Q9Y6B6,P01130,P38571,Q15800,Q10471,Q15904,P23786,P50402,Q9NZJ7,Q14739,Q9BV10,P09622,Q9Y285,Q9Y4P3,P31751 24 +Personality changes 0.5584510493441593 1.7811845857801738 0.0748823009462362 1.0 0.7982383413766796 17 P04062,Q13501,P03886,P03915 4 +Ventricular hypertrophy 0.5231307780535378 1.77906377859933 0.0752293062424485 1.0 0.7982383413766796 37 O75844,O75787,P12235,Q9BV10,P36543,Q07021,P06280,Q6NUK1,P00533,P10253,P23786,P03886,Q9H9S5,P03915 14 +Mixed demyelinating and axonal polyneuropathy 0.7864173228346383 1.7763078864362534 0.0756821840618222 1.0 0.7982383413766796 5 P07196,P03915,P03886,P00403 4 +Increased ldl cholesterol concentration 0.6279972112958422 1.7759340818337368 0.07574378265255 1.0 0.7982383413766796 11 P38571,P04114,P01130,Q8N511 4 +Hyperlipoproteinemia 0.6279972112958422 1.7759340818337368 0.07574378265255 1.0 0.7982383413766796 11 P38571,P04114,P01130,Q8N511 4 +Mild short stature 0.8408531989874513 1.7745133402588174 0.0759782774650965 1.0 0.7982383413766796 4 P10644,Q8WVQ1 2 +Abnormal circulating igm level 0.5836215451774567 1.773518786165093 0.0761427817683206 1.0 0.7982383413766796 15 Q15904,P15260 2 +Cognitive impairment 0.4504717765970974 1.769795155909866 0.0767612711463561 1.0 0.7982383413766796 170 O75569,Q13501,P61916,O96008,P36543,O95470,O00592,Q9Y287,P07602,Q9H6K4,Q15526,P05067,Q9H9S5,P54802,P04062,O15118,P40855,Q8NHS3,Q99720,P06280,O95831,Q9NZ08,Q9Y619,P50897,Q92673,P03886,Q13510,P03915,P10644,P01889,P16278,P06865,P07686,P00403,Q14108,Q9H2C2,P17900,Q9Y2R0,P27544,Q6DKK2,O95169,Q9NZJ7,P12235,P21964,P35637,Q9Y487,O75503,O76024,P11166,O60313,P07196,Q5XKP0,Q9BQE5 53 +Infantile muscular hypotonia 0.4616062744368605 1.768713406686695 0.076941713806732 1.0 0.7982383413766796 64 P16870,Q9NZJ7,P16278,Q9Y487,P36543,Q99519,P10253,P07602,Q2TAA5,Q15526,Q15043,Q96J02,O00754,P17900,P03886,Q9H9S5,Q13510,P03915 18 +Cardiovascular calcification 0.6357573422406435 1.7683448811923208 0.0770032651013705 1.0 0.7982383413766796 10 P04114,O75844,P01130 3 +Abnormality of the chin 0.4056974632390384 1.7607469797141566 0.0782812373599752 1.0 0.7990280071710129 78 O75844,P55011,Q7LGA3,Q96J02,Q9NVI7,P19022,O00754,Q86UE8,Q9H490,P10644,Q9UHX1,P16278,Q6NUK1,Q7RTS9,Q92581,Q07954,Q9Y4P3,P11233,P36543 19 +Cytochrome c oxidase negative muscle fibers 0.7083325106792235 1.7587320992460376 0.0786230225807 1.0 0.7990280071710129 7 Q9Y2R0,P12235 2 +Recurrent aspiration pneumonia 0.7290771445796593 1.758664794701599 0.0786344604108244 1.0 0.7990280071710129 6 P04062,Q6NUK1,Q13510 3 +Ectopic anus 0.6042163328658031 1.7569752542420756 0.0789220271961981 1.0 0.7990280071710129 13 Q5SZK8,Q6NUK1,P16435,P48651,P53701,Q16531 6 +Unexplained fevers 0.7277272441641659 1.7523433644166715 0.0797147836807579 1.0 0.7990280071710129 6 Q9HC07,P07602 2 +Abnormality of exocrine pancreas physiology 0.5540176948226059 1.7518649395011034 0.0797970345098513 1.0 0.7990280071710129 17 Q5HYI8,Q9UHX1,P09601 3 +Dysdiadochokinesis 0.566117645376289 1.7434330430528806 0.0812580006335113 1.0 0.7990280071710129 16 O75503,P98155,Q13501 3 +Perseveration 0.6307704307080649 1.7414052493355128 0.0816125687224722 1.0 0.7990280071710129 10 P61916,Q13501 2 +Progressive gait ataxia 0.679743580640263 1.7403791122229126 0.0817924707837345 1.0 0.7990280071710129 8 O14773,P07602 2 +Resting tremor 0.5379651350137303 1.7387087293956154 0.0820860097732369 1.0 0.7990280071710129 18 P04062,P12235,O75787,O00592,P07602,Q9BPX6,Q9NZJ7 7 +Thoracic scoliosis 0.6211947484070806 1.7382632469489772 0.0821644392427356 1.0 0.7990280071710129 11 O75844,Q9UHX1 2 +Cutis laxa 0.5219585576191286 1.7364085994331813 0.082491612811095 1.0 0.7990280071710129 32 O75787,Q9Y487,Q9BV10,Q04656,Q6NUK1,O96000,P38435,Q15904,Q9Y4P3,P36543 10 +Abnormal pelvis bone morphology 0.8308192726704836 1.733245679680735 0.0830520110855019 1.0 0.7990280071710129 4 P16435,Q04656 2 +Calcification of the aorta 0.7226051230747892 1.7283223701978674 0.0839304446094519 1.0 0.7990280071710129 6 P04114,P01130 2 +Abnormal femoral neck morphology 0.5166388580848946 1.7276747002582151 0.0840465618560744 1.0 0.7990280071710129 37 O75844,P55011,Q9Y487,P16278,P04066,Q04656,O95831,Q9Y619,O00754,Q8WVQ1,Q96HY6,Q96A33 12 +Abnormal sella turcica morphology 0.6766821629052822 1.7250222702377325 0.0845234591587151 1.0 0.7990280071710129 8 P16278,P08236,O00754 3 +Abnormality of the upper respiratory tract 0.3941126240118124 1.7248329298616092 0.0845575854251614 1.0 0.7990280071710129 100 Q13501,P07602,Q13277,P54802,P04066,Q68CQ7,O00754,P15586,Q13510,P10644,Q9UHX1,P01889,P16278,Q5SZK8,P00533,Q96HY6,Q9NZJ7,Q14739,P21964,Q9BV10,Q03518,P08236,P16435 23 +Redundant skin 0.5219026472379364 1.7205449734028255 0.0853334260286813 1.0 0.7990280071710129 27 Q9BV10,Q9Y487,Q04656,Q6NUK1,O96000,P38435,Q9Y4P3,P36543 8 +Aplasia hypoplasia involving the femoral head and neck 0.617455224081464 1.7174913063834574 0.0858894415295712 1.0 0.7990280071710129 11 O95831,P15260,Q8WVQ1 3 +Cerebral amyloid angiopathy 0.9908226810881682 1.7138768677805876 0.0865513422582013 1.0 0.7990280071710129 2 Q9Y287 1 +Thoracolumbar kyphosis 0.7194621507206382 1.7135559413576134 0.0866103110636551 1.0 0.7990280071710129 6 P08236,O00754 2 +Abnormality of the larynx 0.5001586881863507 1.7127471195252542 0.0867590724038065 1.0 0.7990280071710129 47 Q14739,Q13501,Q9UHX1,P35637,P21964,Q15165,P36543,Q5SZK8,Q68CQ7,P16435,P07602,Q96HY6,Q13510,Q9NZJ7 14 +Purpura 0.5206457600543112 1.7124610351633016 0.0868117394015319 1.0 0.7990280071710129 22 P10644,P21964,Q16625,P51798,P38435,Q99519 6 +Hydrocephalus 0.4060811999928936 1.7119172278765469 0.0869119233310677 1.0 0.7990280071710129 77 P51798,Q99519,P53701,P07237,Q9H9S5,P04062,P40855,Q8TAA9,O00754,P07942,Q9H490,P10644,Q9BXW9,Q6NUK1,P23786,O43505,P21964,P08236,P11166,P16435,P48651,O95202 22 +Absent hypoplastic paranasal sinuses 0.93054843396743 1.7069712119506195 0.0878274033185151 1.0 0.7990280071710129 3 P04066 1 +Abnormal visual fixation 0.717763286722231 1.7055658106591811 0.0880889494936811 1.0 0.7990280071710129 6 Q5KU26,P04062 2 +Abnormally lax or hyperextensible skin 0.5027873604523698 1.7045818098086405 0.0882724462767814 1.0 0.7990280071710129 45 P04062,O75787,Q9UHX1,Q9Y487,Q9BV10,Q04656,Q15555,Q6NUK1,O96000,P38435,Q15904,Q9NWM8,Q9Y4P3,P36543 14 +Abnormal circulating androgen level 0.5838527888244986 1.7021180779971952 0.0887332356688923 1.0 0.7990280071710129 14 P51809,Q13423,P16870 3 +Reduced visual acuity 0.4038967519130464 1.70152434277949 0.088844570751662 1.0 0.7990280071710129 114 P51798,Q9Y6M9,P07602,P53701,Q15043,Q13277,Q9H9S5,Q8NHS3,Q9NZ08,P50897,P03886,Q9UHX1,P01889,P16278,P06865,Q5SZK8,P07686,Q86Y39,O43676,P17900,O43505,Q9NZJ7,P09622,Q15555,Q9H061,O60313 26 +Facial hypotonia 0.6226789102118718 1.697532350109051 0.0895960603759535 1.0 0.7990280071710129 10 P10253 1 +Sclerocornea 0.6225383413094858 1.6967684173037685 0.0897404519415445 1.0 0.7990280071710129 10 O95202,P53701,O75569,Q6NUK1 4 +Petechiae 0.5929748135496267 1.69105734481765 0.0908258508700623 1.0 0.7990280071710129 13 P10644,P51798,Q99519,Q16625 4 +Abnormal aortic valve physiology 0.5097781299787414 1.690654366914881 0.0909028345634992 1.0 0.7990280071710129 39 P04062,O75844,Q9UHX1,P01889,P16278,P04114,Q9NZ08,O00754,Q9Y4P3,P01130,Q96PU5 11 +Global brain atrophy 0.515290710405182 1.673527597476639 0.0942234783425286 1.0 0.7990280071710129 22 Q13501,Q9UHX1,P07602,Q15526,O95169,Q9NZJ7 6 +Corpus callosum atrophy 0.5898483396190596 1.6726464149675453 0.0943969238385631 1.0 0.7990280071710129 13 O75503,O00754,O60313,O00429 4 +Diminished movement 0.5282919210937159 1.6720351535783955 0.0945173903136442 1.0 0.7990280071710129 18 O95831,P04062,O00592,P12235 4 +Cerebral white matter atrophy 0.5282112979328584 1.671477635938467 0.094627372465069 1.0 0.7990280071710129 18 O75503,P51572,O00429,Q9Y263,O43175,O60313,Q9UNE7,Q2TAA5,O00754 9 +Neoplasm of the gallbladder 0.815646551095204 1.67059526509379 0.0948016483732372 1.0 0.7990280071710129 4 P07602 1 +Biliary tract neoplasm 0.815646551095204 1.67059526509379 0.0948016483732372 1.0 0.7990280071710129 4 P07602 1 +Cns demyelination 0.5991400844720374 1.6677754890450895 0.0953603033530829 1.0 0.7990280071710129 12 P40855,P07602,P51648 3 +Skin nodule 0.5146081102542339 1.66515945454139 0.095880947682106 1.0 0.7990280071710129 25 P16615,P06280,P04114,Q9NZ08,P01130,Q13510 6 +Skeletal muscle hypertrophy 0.5036313816797098 1.6610666302696455 0.0967000654970799 1.0 0.7990280071710129 41 P16278,P04066,P07686,P10253,Q9H9S5,O00754,Q7LGA3,Q96A33 8 +Generalized hyperkeratosis 0.7598439179974885 1.6594472982299795 0.0970256920780232 1.0 0.7990280071710129 5 P04066 1 +Type ii lissencephaly 0.8127918192811602 1.6587756628251182 0.0971610061951107 1.0 0.7990280071710129 4 O43505,Q9H9S5 2 +Corneal erosion 0.7596767001365429 1.658708332452022 0.0971745795352387 1.0 0.7990280071710129 5 P39210,P51648 2 +Aplastic clavicle 0.8123975073794579 1.657142299328419 0.0974907089523506 1.0 0.7990280071710129 4 Q04656,Q9Y619,P48651 3 +Epispadias 0.8123975073794578 1.657142299328419 0.0974907089523506 1.0 0.7990280071710129 4 P53701,Q9Y619,P48651 3 +Mitochondrial inheritance 0.7589452825927101 1.6554755560911547 0.097828070791561 1.0 0.7990280071710129 5 P03915,P03886,Q15526 3 +Agnosia 0.6138369413568053 1.649364584393029 0.0990729656687063 1.0 0.7990280071710129 10 O75787,P05067,Q92673 3 +Chronic pulmonary obstruction 0.6855003869822456 1.6480109083929146 0.0993504327416034 1.0 0.7990280071710129 7 P06280,P09601 2 +Blurred vision 0.7571253536926426 1.6474280978812652 0.09947008396053 1.0 0.7990280071710129 5 P04439,P03886 2 +Sea blue histiocytosis 0.9154098360655714 1.6470822200312285 0.0995411471557508 1.0 0.7990280071710129 3 P16278,O15118 2 +Erythema 0.5113904130608622 1.645080026969478 0.0999533088730311 1.0 0.7990280071710129 22 P01889,Q06136,P00533,Q07954,P53701,P51648,P07858,P03886,P03915 9 +Decreased muscle mass 0.5243582877265671 1.6447991282180945 0.1000112420274015 1.0 0.7990280071710129 18 Q9Y487,P04066,Q8TAA9,Q92581,O95202,P36543 6 +Steroid resistant nephrotic syndrome 0.7048535823167146 1.6446578267048133 0.1000403944718197 1.0 0.7990280071710129 6 Q92621,Q96J84,Q8N1F7 3 +Fatigable weakness of respiratory muscles 0.5503110647894518 1.641596284345735 0.1006736982173446 1.0 0.8005154153898651 16 Q15165,Q13501,P35637,Q68CQ7 4 +Infantile axial hypotonia 0.6354764417371657 1.6377586463591125 0.1014720512823883 1.0 0.8005154153898651 9 P17900,P07602,O00754,Q9NZJ7 4 +Poor wound healing 0.6833939236835943 1.6377379816265711 0.1014763638237898 1.0 0.8005154153898651 7 P15529,P04062,O15269 3 +Vertebral segmentation defect 0.5104330865625984 1.6359663987582431 0.1018466199586511 1.0 0.8005154153898651 28 Q9UHX1,Q5SZK8,Q8TAA9,Q9Y619,P16435,O95202,Q9H9S5 7 +Fractures of the long bones 0.8057395902925254 1.629535320546913 0.1031997440246614 1.0 0.8005154153898651 4 Q13501 1 +Hyperlipidemia 0.5093052598177075 1.629293330259756 0.1032509374298642 1.0 0.8005154153898651 29 O75844,P38571,P06280,O95470,P04114,P23786,P01130,P50402,P31751 9 +Bone pain 0.5097727968165288 1.6292829850893418 0.1032531264159917 1.0 0.8005154153898651 25 P10644,P04062,Q13501,P51798,P07602,Q14108 6 +Abnormal intraocular pressure 0.7517475085796395 1.6236184432790874 0.1044572667477088 1.0 0.8038817654024434 5 P04439 1 +Areflexia of lower limbs 0.5475045167465382 1.6234094724378918 0.1045019011356083 1.0 0.8038817654024434 16 P12235,Q13501,O75787,Q16637,O60313,Q9H6K4,P07196 7 +Barrel shaped chest 0.7516404199474979 1.623143879050848 0.1045586514722449 1.0 0.8038817654024434 5 P04066,Q14739,Q32P28,Q7RTS9 4 +Broad ribs 0.7000590979815562 1.6219533276856597 0.104813341841593 1.0 0.8044990780620114 6 P16278,Q04656,Q7RTS9 3 +Abnormal saccadic eye movements 0.5077310720134834 1.6163005312160774 0.1060293520427133 1.0 0.8055534526388001 23 P04062,P51798,Q8IV08,O14773,Q15526 5 +Hypokinesia 0.6077723563945845 1.6161930096859505 0.1060525896726427 1.0 0.8055534526388001 10 O95831,P04062,P12235 3 +Poor gross motor coordination 0.8020852216606986 1.6143606669013224 0.1064492180945952 1.0 0.8055534526388001 4 O75503 1 +Focal white matter lesions 0.6982151265828551 1.6132092618472331 0.1066990519309007 1.0 0.8055534526388001 6 P12235,P42345,O00584 3 +Hypercholesterolemia 0.5797332607332331 1.6128537023360934 0.1067762956812714 1.0 0.8055534526388001 13 Q15904,P04114,P01130,Q8N511 4 +Abnormality of circulating adrenocorticotropin level 0.6542140834796092 1.6116127629778425 0.1070462316209808 1.0 0.8055534526388001 8 P10644,Q13423 2 +Dyslexia 0.6536464516273813 1.608731927274506 0.1076749713673996 1.0 0.8065827267365204 8 P11166,Q13501 2 +Meningocele 0.5790130041628881 1.6085829867442545 0.1077075568327978 1.0 0.8065827267365204 13 Q5SZK8,Q8TAA9,Q9H9S5 3 +Abnormality of bladder morphology 0.5966714287645731 1.6012449796845574 0.1093226699953875 1.0 0.8115716290998516 11 P16435,Q5SZK8,Q9Y4P3,Q04656 4 +Intracellular accumulation of autofluorescent lipopigment storage material 0.9632907243526712 1.5999698453167026 0.1096052731257766 1.0 0.8115716290998516 2 O75503 1 +Retinal thinning 0.9616519174041296 1.593182183017894 0.1111193269916985 1.0 0.8150522186386842 2 P04439 1 +Abnormality of the shoulder girdle musculature 0.5036644696298528 1.5915367793454858 0.1114888250511618 1.0 0.8150522186386842 31 O14979,Q13501,P12235,Q9Y487,P07602,Q9H9S5,O60313,P50402,Q9NZJ7 9 +Vascular calcification 0.672606703536472 1.5849824789925908 0.1129703151791599 1.0 0.8219748642294394 7 P04114,P01130 2 +Inappropriate behavior 0.5410331185580546 1.581356142715991 0.1137966293610988 1.0 0.8240876785600451 16 P17900,Q13501,P07602,Q92581 4 +Degeneration of the lateral corticospinal tracts 0.6693766900810922 1.5691387863657678 0.1166156038593171 1.0 0.8325788817035349 7 Q13501,P35637 2 +Variable expressivity 0.4210617049239687 1.562688669611504 0.118125840712391 1.0 0.8325788817035349 70 Q70HW3,O95470,P07602,Q15526,Q9H9S5,P56192,P03886,Q6P4A7,Q53H12,Q13510,P03915,P00403,P17900,Q9NZJ7,P00374,P09622,P11166,Q9H061,Q8WVQ1,P07196 20 +Optic disc pallor 0.4903280442789061 1.5617977289470688 0.1183356469903507 1.0 0.8325788817035349 42 Q8NHS3,P04439,Q9UG56,P51798,O96000,Q9Y6M9,Q96CU9,O95831,Q86Y39,Q9Y287,O43676,O00754,Q9H061,O60313,Q13277,P03886 16 +Abnormal morphology of the abdominal musculature 0.5802090910580535 1.5585942547964462 0.1190924436969853 1.0 0.8325788817035349 12 O00462,Q04656,Q96JJ3,Q8WVQ1 4 +Bone fracture 0.6670007294125985 1.5574707913882886 0.119358750109483 1.0 0.8325788817035349 7 Q13501 1 +Abnormal sternal ossification 0.7368068844520349 1.5572469370785085 0.1194118683707157 1.0 0.8325788817035349 5 Q9Y619 1 +Retinal dysplasia 0.6430006212706716 1.5545646078677169 0.1200497983273325 1.0 0.8325788817035349 8 O43505,Q9H9S5 2 +Clitoral hypoplasia 0.6856097526223316 1.553263045004463 0.1203603050900115 1.0 0.8325788817035349 6 Q9Y619,Q15042,O75419 3 +Hypoplastic labia minora 0.6856097526223316 1.553263045004463 0.1203603050900115 1.0 0.8325788817035349 6 Q9Y619,Q15042,O75419 3 +Very long chain fatty acid accumulation 0.7355296532830539 1.551558333670994 0.1207679393755247 1.0 0.8325788817035349 5 Q5T8D3,P40855,O75381 3 +Stroke like episode 0.6852278463065946 1.5514422707874531 0.1207957318198793 1.0 0.8325788817035349 6 O76024,P03886,P03915 3 +Abnormality of fundus pigmentation 0.685113145897839 1.550895374343301 0.1209267591299554 1.0 0.8325788817035349 6 Q9Y619,P49815,P38435 3 +Abnormal protein o linked glycosylation 0.8911475409836052 1.5507700322695417 0.1209568046690696 1.0 0.8325788817035349 3 Q15904,Q8N511 2 +External ophthalmoplegia 0.5583058063289674 1.54642302424309 0.1220024371455341 1.0 0.8325788817035349 14 P12235,Q07021,O60313,P03886,P03915 5 +Supravalvular aortic stenosis 0.6412381606332636 1.5455721738864308 0.1222079257685864 1.0 0.8325788817035349 8 P04114,P01130 2 +Broad palm 0.6178015130641056 1.5444204529105217 0.1224865083460353 1.0 0.8325788817035349 9 P10644,O95831,Q14739,Q7RTS9 4 +Aspiration 0.5946440156287115 1.5440211245571445 0.1225832151492329 1.0 0.8325788817035349 10 P06865 1 +Segmental peripheral demyelination remyelination 0.7845908106012744 1.5415136721478109 0.1231918180030047 1.0 0.8325788817035349 4 P03886,P03915 2 +Posterior fossa cyst 0.94886922320551 1.540222925796292 0.1235060234565157 1.0 0.8325788817035349 2 Q9UHX1 1 +Decreased circulating androgen concentration 0.5856724975233897 1.5391959863808176 0.123756457182713 1.0 0.8325788817035349 11 P51809,P16870 2 +Vascular skin abnormality 0.3962135685343785 1.5390148023319206 0.123800682583441 1.0 0.8325788817035349 120 O75844,Q16625,P10619,P51798,Q99519,P53701,P07858,P04062,P04066,P06280,Q8IZA0,P03886,P03915,P10644,Q9BXW9,P01889,Q96JJ3,P16278,Q06136,Q04656,Q6NUK1,P00533,P00403,Q14108,O00462,Q14739,P21964,Q9Y487,P38435,Q07954,P51648,P36543 32 +Aplasia hypoplasia of the capital femoral epiphysis 0.6824674982065057 1.5382742489723318 0.1239815732651632 1.0 0.8325788817035349 6 Q7LGA3,Q8WVQ1 2 +Agitation 0.4910179408714757 1.538074234564168 0.1240304649850847 1.0 0.8325788817035349 39 P10644,P04062,Q13501,P35637,P42892,O96008,Q15165,Q68CQ7,P35610,P08069,O00592,Q92673,Q92804,P05067 14 +Schizophrenia 0.4970366707079777 1.5372995369807363 0.1242199748234009 1.0 0.8325788817035349 23 P04062,P21964,P16615,P07602,Q9BQE5,Q9NZJ7 6 +Young adult onset 0.5932135693176113 1.5361280135023925 0.1245069869336097 1.0 0.8325788817035349 10 O15118,P07602,P38435 3 +Central apnea 0.6153034079582678 1.5311645409182164 0.1257287319731121 1.0 0.8325788817035349 9 P11166,P07602,Q9NZJ7 3 +Mania 0.5556394808129737 1.5300431629357103 0.1260060453500771 1.0 0.8325788817035349 14 P12235,P21964,P16615,P03886,P03915 5 +Opsoclonus 0.8855414001234899 1.5284679741103342 0.1263963891628652 1.0 0.8325788817035349 3 P51798 1 +Saccadic oscillation 0.8855414001234899 1.5284679741103342 0.1263963891628652 1.0 0.8325788817035349 3 P51798 1 +Abnormal tongue morphology 0.4213459039922914 1.5266894928858252 0.1268382413747828 1.0 0.8325788817035349 69 O75844,P01889,Q15042,P16278,P04066,Q5SZK8,Q6NUK1,P07686,Q99519,P10253,Q9H9S5,O00754,Q7LGA3,Q96A33 14 +Slow saccadic eye movements 0.6143568119365249 1.5261375197595235 0.1269756197427409 1.0 0.8325788817035349 9 Q8IV08 1 +Stuttering 0.7295547992738554 1.5249178380285378 0.1272795920514666 1.0 0.8325788817035349 5 P03886,P03915 2 +Abnormal placenta morphology 0.5909537636052187 1.5236470431186104 0.127596904888249 1.0 0.8325788817035349 10 P16278,O75844 2 +Postural tremor 0.5318435541107077 1.5213633663294004 0.128168676673231 1.0 0.8325788817035349 16 O75569,P35637,O14773,Q14108,Q9H6K4,P03886,P03915 7 +Abnormality of skull ossification 0.5643590184253445 1.5213254848865565 0.1281781779441844 1.0 0.8325788817035349 13 P54802,O75844,Q9HC21,Q6NUK1 4 +Flattened epiphysis 0.7795998595464577 1.5206739222425376 0.128341685984755 1.0 0.8325788817035349 4 Q8WVQ1 1 +Coarse hair 0.4934309831026963 1.5200824573940892 0.1284902529796043 1.0 0.8325788817035349 20 P54802,Q9Y487,Q04656,Q6NUK1,P15586,Q96A33 6 +Hallucinations 0.4760086301617399 1.5187740742347977 0.1288193738391598 1.0 0.8325788817035349 48 P04062,Q13501,P21964,O75503,Q9BQE5,O76024,O00592,P07602,P50897,Q92673,O00754,O60313,Q6DKK2,P05067,Q9NZJ7 15 +Abnormal conjunctiva morphology 0.4945371136300584 1.5182855737719614 0.1289424228411368 1.0 0.8325788817035349 30 O00462,P02786,P01889,P04066,P06280,P10619,Q9NZ08,Q13510 8 +Mask like facies 0.5632914561754614 1.5149418549824116 0.129787129611941 1.0 0.8325788817035349 13 P04062,Q04656,Q9H9S5 3 +Submucous cleft of soft and hard palate 0.493920518864111 1.51417732336682 0.1299808714775505 1.0 0.8325788817035349 23 Q7LGA3,O75844,Q9Y619,Q9H9S5 4 +Coxa vara 0.5305845611839864 1.5131195920874163 0.1302492838421085 1.0 0.8325788817035349 16 Q9Y487,Q04656,O95831,Q8WVQ1,Q96HY6 5 +Poikilocytosis 0.562841423756641 1.512249760965261 0.1304703363582768 1.0 0.8325788817035349 13 P04114,P11166 2 +Short thorax 0.7261066956572615 1.50952206291222 0.1311654214373843 1.0 0.8345739159871086 5 Q5SZK8,Q99519,P11166 3 +Bilateral sensorineural hearing impairment 0.4936111113877929 1.5085218517431993 0.1314210183114026 1.0 0.8350484262679068 25 Q13501,P55011,Q9NZJ7,P35637,P00403,P07602,P03886,P03915 8 +Abnormality of the nasal bone 0.7760297799917375 1.5057525588227645 0.1321307060575085 1.0 0.8356812939697422 4 P10644 1 +Recurrent infection of the gastrointestinal tract 0.6753465245587658 1.5042420607716376 0.1325190514098067 1.0 0.8356812939697422 6 O00754,P15260 2 +Macular degeneration 0.551444641825534 1.5042256067115656 0.1325232865701706 1.0 0.8356812939697422 14 P04062,P51648,P50897,P04439 4 +Abnormal thalamic size 0.7756641521810284 1.5042237337023887 0.1325237686763216 1.0 0.8356812939697422 4 P11166,Q9H9S5,Q9UPT5 3 +Asymmetric septal hypertrophy 0.9400196656833824 1.503551262491557 0.1326969482698738 1.0 0.8356812939697422 2 P54802 1 +Generalized hyperpigmentation 0.5704353253938925 1.5017912036368712 0.1331510407690788 1.0 0.8356812939697422 12 P51648 1 +Short stepped shuffling gait 0.8783091619470993 1.4996756416989256 0.133698443193627 1.0 0.8375091991434627 3 O00592 1 +Ragged red muscle fibers 0.5284703874581298 1.499263091072588 0.1338053934031502 1.0 0.8375091991434627 16 P12235,Q70HW3,Q9H2D1,O95831,P03886,P03915 6 +Coronary artery aneurysm 0.938708620124549 1.4981185116764326 0.1341024623229889 1.0 0.8382312448454581 2 P04114 1 +Astrocytosis 0.6547598298551118 1.4971804177267571 0.13434631928617 1.0 0.8386191757335619 7 Q13501,P42345 2 +Abnormal neuron morphology 0.491876004409369 1.4948861476493187 0.13494415808492 1.0 0.8410657062326365 28 Q13501,P35637,Q15165,Q99720,Q68CQ7,Q16637,Q13510 7 +Metatarsus valgus 0.8762601157623793 1.491514231436321 0.1358265376398373 1.0 0.8433865626340146 3 Q9H9S5 1 +Centrocecal scotoma 0.7721329524874689 1.4894523188835624 0.1363683002526268 1.0 0.8433865626340146 4 P03886,O60313 2 +Multifocal cerebral white matter abnormalities 0.7215768336355681 1.4892731662412488 0.1364154508251844 1.0 0.8433865626340146 5 P10253 1 +Hypoplasia of the odontoid process 0.671867932787555 1.4875856139003791 0.1368602096666777 1.0 0.8433865626340146 6 P16278,P08236,O95831 3 +Psychosis 0.4905526492330257 1.4874642518987644 0.1368922380107562 1.0 0.8433865626340146 30 P10644,O15118,P61916,Q13501,O76024,Q9Y287,Q6DKK2,P03886,P03915 9 +Shuffling gait 0.5753258515127571 1.4805075819548412 0.1387378388346216 1.0 0.848803250058501 11 O75844,O00592 2 +Pustule 0.7694409756325047 1.4781841473205286 0.1393584958609226 1.0 0.8514711806707763 4 P07858,P53634 2 +Corneal dystrophy 0.7686855243175958 1.4750208444848023 0.1402069394810559 1.0 0.8543918253977686 4 P06280 1 +Atrophy degeneration involving the corticospinal tracts 0.5653268841069132 1.4719895752785557 0.1410236926943664 1.0 0.8559767031567268 12 Q9Y4P3,Q13501,P35637 3 +Aplasia hypoplasia of the abdominal wall musculature 0.6267140788841463 1.471209639487299 0.1412344310982056 1.0 0.8560969042216605 8 O00462,Q04656,Q8WVQ1 3 +Cogwheel rigidity 0.7673395486470833 1.4693836573914425 0.1417287574585564 1.0 0.8560969042216605 4 P12235 1 +Recurrent bacterial infections 0.4856841993585758 1.4679489713484264 0.1421180844922476 1.0 0.8560969042216605 19 Q15904,P53634,O00754,P15260 4 +Generalized clonic seizure 0.7666821750577775 1.466629915755254 0.1424767574080556 1.0 0.8560969042216605 4 P07602 1 +Abnormal cerebral artery morphology 0.5233013345767518 1.4653166166213738 0.1428345550549421 1.0 0.8560969042216605 16 P10644,P04114,P10253,P01130,P05067 5 +Abnormal circulating follicle stimulating hormone concentration 0.6028190174154917 1.4646912680649409 0.1430051683520263 1.0 0.8560969042216605 9 P51809,P16870 2 +Enlarged ovaries 0.7653756060652216 1.4611556470426843 0.1439727317602082 1.0 0.8560969042216605 4 P10644 1 +Slow pupillary light response 0.8683940231740942 1.4601694797153395 0.1442435010623315 1.0 0.8560969042216605 3 P07602 1 +Abnormal pupillary light reflex 0.8683940231740942 1.4601694797153395 0.1442435010623315 1.0 0.8560969042216605 3 P07602 1 +Pedal edema 0.6461548529211383 1.4546277661911395 0.1457723398208694 1.0 0.8560969042216605 7 P10644,Q14108 2 +Posterior embryotoxon 0.5097076771879718 1.4542325942117265 0.145881831235517 1.0 0.8560969042216605 17 Q7LGA3,P21964,P53701,P40855 4 +Deep plantar creases 0.713739915467916 1.45418218995059 0.1458958014118541 1.0 0.8560969042216605 5 P42345,Q9Y487 2 +Gingival fibromatosis 0.763575367437415 1.453610760832154 0.1460542518149679 1.0 0.8560969042216605 4 Q15392,Q96JJ3 2 +Clonic seizure 0.7123225232666249 1.4478279136749894 0.1476651840475535 1.0 0.860075118701218 5 P07602 1 +Negativism 0.9255981645362202 1.4438017578729614 0.1487947473946795 1.0 0.8602680106325914 2 Q9BQE5 1 +Social and occupational deterioration 0.9255981645362202 1.4438017578729614 0.1487947473946795 1.0 0.8602680106325914 2 Q9BQE5 1 +Microdontia 0.48485453995215 1.4418313469196682 0.1493499573977688 1.0 0.8602680106325914 29 Q9Y487,Q15555,Q6NUK1,Q9Y619,Q7LGA3,Q9Y4P3,Q96A33 7 +Deposits immunoreactive to beta amyloid protein 0.8637897811660277 1.4418137821869637 0.1493549137774024 1.0 0.8602680106325914 3 P05067 1 +Finger agnosia 0.8637897811660277 1.4418137821869637 0.1493549137774024 1.0 0.8602680106325914 3 P05067 1 +Abnormal circulating copper concentration 0.7106302547427696 1.4402383697650305 0.1497999710850217 1.0 0.8605569945394835 5 Q10567,Q15904,Q9Y487 3 +Abnormal metatarsal morphology 0.4841184893577911 1.4358529100946755 0.1510442004074823 1.0 0.8666254931339752 26 P10644,Q7RTS9,P08236,P16435,Q8WVQ1,O95202,O43505,Q9H9S5 8 +Abnormal protein glycosylation 0.5068024187714409 1.4344444390545863 0.1514454737720356 1.0 0.8676810950564302 17 O75787,Q9Y487,Q9BT22,Q10471,Q8N511,Q15904,P36543 7 +Delayed epiphyseal ossification 0.7588721390621394 1.4338874955112084 0.1516043708249475 1.0 0.8676810950564302 4 Q9UG56 1 +Abnormal circulating igg level 0.5399018264400262 1.4328924504198146 0.151888575122657 1.0 0.8682304796044822 14 Q15904,P15260 2 +Vertebral fusion 0.5665735065902016 1.4306317227069496 0.1525357907891118 1.0 0.8692009030140159 11 Q8TAA9,Q9UHX1,Q9H9S5 3 +Mandibular aplasia 0.7574345658867359 1.427855668341709 0.153333405862611 1.0 0.8692009030140159 4 Q9Y619,P53701 2 +Retinal degeneration 0.4470354776125945 1.4261202397028452 0.1538336374584719 1.0 0.8692009030140159 57 P04062,O75503,P04439,Q9UG56,P04114,O14773,P50897,O00754,Q9H2C2,Q7LGA3,O60313,P51648,Q9H9S5,Q13510 14 +Peripheral axonal neuropathy 0.465236771316889 1.4235843978009244 0.1545668149601302 1.0 0.8692009030140159 48 Q9NVI7,P56192,P12235,Q9NZJ7,P39210,P07196,Q6DD88,Q9HC21,Q8IV08,P00403,O95831,O76024,P07602,O60313,O15269,Q9BPX6,P03886,P03915 18 +Fat malabsorption 0.5725634976315122 1.4215704794347888 0.1551509797253045 1.0 0.8692009030140159 10 Q9Y6B6,P38571,Q96A33 3 +Atrioventricular canal defect 0.6169877572505573 1.4211662574001367 0.1552684316328891 1.0 0.8692009030140159 8 P19022,P17612,Q9UHX1,O60826,O75419 5 +Hypopigmented skin patches 0.4821247287405637 1.4206963626041762 0.1554050504367619 1.0 0.8692009030140159 26 Q9BXW9,P21964,Q9NZJ7,P53634,P42345,Q92889,P07602,P53701,Q8IZA0,P18074 10 +Emg neuropathic changes 0.4808792758814729 1.4200270294951394 0.1555998121542157 1.0 0.8692009030140159 22 P39210,Q04656,O14773,P07602,O60313,Q13510,Q9NZJ7 7 +Hypopigmentation of the fundus 0.7553322470434721 1.4190320260407476 0.1558896793457993 1.0 0.8692009030140159 4 Q9Y619,P38435 2 +Xanthelasma 0.8580288061333038 1.4188394548177132 0.1559458270282609 1.0 0.8692009030140159 3 P04114 1 +Tendon xanthomatosis 0.8580288061333038 1.4188394548177132 0.1559458270282609 1.0 0.8692009030140159 3 P04114 1 +Laryngomalacia 0.5374115884070118 1.4174488966051424 0.1563517254008934 1.0 0.8692009030140159 14 P16435,P21964,P07602,Q9NZJ7 4 +Short ribs 0.5934073514401543 1.414339945779482 0.1572621136347891 1.0 0.8692009030140159 9 Q9Y619,Q96HY6,Q9BV10 3 +Aplasia hypoplasia involving the sinuses 0.7529710286181739 1.4091181259987786 0.1588002419511482 1.0 0.8692009030140159 4 P04066 1 +Bilateral tonic clonic seizure with generalized onset 0.5923415363570207 1.4086256088515576 0.1589459023627559 1.0 0.8692009030140159 9 P04062,P11166,Q92581,Q9Y320,Q13510 5 +Ankle clonus 0.5349681875405327 1.402277775568528 0.1608323143298617 1.0 0.8692009030140159 14 O75787,Q8N0X7,Q9NW15,P07602,Q15043,Q9NP72,Q9NZJ7 7 +Pulmonary embolism 0.7021615169487831 1.402210804006109 0.1608523063302149 1.0 0.8692009030140159 5 Q9NZ08 1 +Hypolipoproteinemia 0.59045894095844 1.3985261628427323 0.1619551217578378 1.0 0.8692009030140159 9 Q9Y6B6,P38571,P04114,Q10471 4 +Thoracic hypoplasia 0.4785413717573975 1.39833756972556 0.1620117209482634 1.0 0.8692009030140159 32 P04062,Q14739,Q9UHX1,Q04656,P51798,Q92581,Q8WVQ1,Q96HY6,Q96A33 9 +Cutaneous syndactyly 0.5525395422844224 1.397068390916718 0.1623930060004506 1.0 0.8692009030140159 12 Q5SZK8 1 +Microretrognathia 0.5337301795768845 1.3945842441036356 0.1631412490678989 1.0 0.8692009030140159 14 Q9UHX1,Q16625 2 +Gastroparesis 0.6117766643613843 1.3942784717505152 0.1632335293163891 1.0 0.8692009030140159 8 O00592,P12235 2 +Mutism 0.500886836677392 1.3940581660210882 0.163300040643086 1.0 0.8692009030140159 17 Q13510,Q13501,P53701,Q92581 4 +Motor seizure 0.3664619899696504 1.3932594448752973 0.1635413496069693 1.0 0.8692009030140159 97 Q96N66,P55011,Q99519,P07602,P04062,P19022,Q8NHS3,Q9Y619,Q01105,Q9Y320,P03886,Q13510,P03915,O75787,P16278,Q6PJG6,P07686,P49815,Q92581,Q9NZJ7,Q96C86,O75503,Q9UBX3,O00429,O43292,P11166,Q9NZ01,Q5XKP0,Q96CW1,P13073,O60508 31 +Absent epiphyses 0.6335968055769587 1.3922916718683545 0.1638340923955636 1.0 0.8692009030140159 7 Q7LGA3,Q8WVQ1 2 +Abnormal coronary artery morphology 0.6112795414207861 1.3917107933736548 0.1640099925532827 1.0 0.8692009030140159 8 P16278,P04114 2 +Arthritis 0.4721375894345413 1.3904646109009948 0.1643878384174582 1.0 0.8692009030140159 40 P04062,O75844,P21964,P10321,P01889,P06280,P51798,Q9NZ08,Q14108,Q8WVQ1,Q96HY6,Q13510 12 +Vertical supranuclear gaze palsy 0.5889216373258109 1.3902734958437502 0.1644458429547768 1.0 0.8692009030140159 9 O15118,Q13501 2 +Peripheral axonal degeneration 0.4275528020659324 1.3900425791045503 0.1645159480989031 1.0 0.8692009030140159 63 P39210,Q8IV08,P07602,Q15526,Q9NVI7,P56192,Q6DD88,Q9HC21,O95831,Q9BPX6,P03886,P03915,P00403,Q6DKK2,Q9NZJ7,P12235,O76024,O60313,O15269,P07196 20 +Pleural effusion 0.5327161580024113 1.3882793376734557 0.1650520015080288 1.0 0.8692009030140159 14 Q14739,P01889,P15529,Q9NZ08,Q9UID3 5 +Metaphyseal widening 0.4765758777357651 1.3879488644083648 0.1651526167781409 1.0 0.8692009030140159 22 Q14739,P16278,Q04656,Q7RTS9,O95831,Q8WVQ1,Q96HY6 7 +Hemivertebrae 0.5664946133308421 1.3876959519426844 0.1652296492137563 1.0 0.8692009030140159 10 Q9Y619,Q9UHX1 2 +Prominent superficial blood vessels 0.550672210081857 1.3860906815866605 0.1657192154064608 1.0 0.8692009030140159 12 O75844,P36543,Q6NUK1,Q9Y487 4 +Abnormality of lower limb epiphysis morphology 0.4743737939006588 1.3850296115984824 0.1660434130469676 1.0 0.8692009030140159 19 Q04656,Q6NUQ1,O95831,Q8WVQ1,Q7LGA3 5 +Prominent sternum 0.8495081967213086 1.3848499437367587 0.16609835567359 1.0 0.8692009030140159 3 P16278,O95831 2 +Aortic valve stenosis 0.587855980151936 1.384549842393461 0.1661901574806767 1.0 0.8692009030140159 9 P16278,O75844 2 +Calvarial hyperostosis 0.6501741019492542 1.383272733687657 0.1665812552043015 1.0 0.8696842964827648 6 P10644 1 +Delayed fine motor development 0.6094064020006296 1.3820318037047703 0.1669619360776904 1.0 0.8696842964827648 8 Q5KU26,P16435,P51798 3 +Gingival bleeding 0.5410984418469695 1.3814609688362292 0.1671372708432441 1.0 0.8696842964827648 13 P10644,Q14108,Q96JJ3 3 +Scrotal hypoplasia 0.4741577283344764 1.378358144921003 0.1680927392836035 1.0 0.8696842964827648 20 Q8TCJ2,Q9BV10,Q5SZK8,Q15555,Q6NUK1,P16435,Q9NP72,P46977,P18074 9 +Vitritis 0.9095378564405188 1.377323723294398 0.1684121838003367 1.0 0.8696842964827648 2 P04439 1 +Narrow vertebral interpedicular distance 0.8469445639978959 1.3746220183867608 0.1692486587290953 1.0 0.8696842964827648 3 P10644 1 +Vertebral arch anomaly 0.8469445639978959 1.3746220183867608 0.1692486587290953 1.0 0.8696842964827648 3 P10644 1 +Severe short stature 0.4754973611551891 1.3738521901279253 0.1694875747968796 1.0 0.8696842964827648 24 Q15392,P16278,P10619,Q7RTS9,Q9Y619,P53701,P48651,Q8WVQ1,Q96HY6 9 +Increased vertebral height 0.9082268108816792 1.3719015857060812 0.1700940767061469 1.0 0.8708187677459668 2 O00754 1 +Juvenile onset 0.4664318284790431 1.3705529508909098 0.1705143582020678 1.0 0.8708343045730949 43 P54802,O15118,P39210,Q8NHS3,P16278,Q04656,P51798,P06280,O14773,Q96J84,Q13510 11 +Hypotension 0.475125451423413 1.368894993652733 0.1710321009077851 1.0 0.8708343045730949 25 P04062,Q13423,Q04656,P07686,P15529,P07602 6 +Abnormal cornea morphology 0.4056885537819532 1.3685149212055292 0.1711509546770115 1.0 0.8708343045730949 150 O75844,Q16625,P55011,P39210,P10619,P04114,Q99519,P53701,Q2TAA5,Q7LGA3,Q9H9S5,P04062,Q9NVI7,P40855,P04066,Q07021,P06280,Q9NZ08,O00754,P01130,Q13510,Q9BXW9,P01889,Q15042,P16278,Q06136,Q6NUK1,Q10471,O43505,Q14739,P12235,P21964,Q15555,P08236,P51648,O95202,Q9Y4P3 37 +Abnormal circulating long chain fatty acid concentration 0.7428665136110065 1.3666532475589106 0.1717340186034843 1.0 0.8708343045730949 4 O75381,P40855,P23786 3 +Bilateral coxa valga 0.9069157653228463 1.3664803181727356 0.171788254316392 1.0 0.8708343045730949 2 O00754 1 +Abnormal auditory evoked potentials 0.5836444602016524 1.3619068134574328 0.1732272956659006 1.0 0.8732992916209601 9 P07196,O60313,P07602,Q9NZJ7 4 +Disproportionate short trunk short stature 0.6930554838744437 1.361241270458429 0.1734374558401643 1.0 0.8732992916209601 5 P16278,Q9UHX1 2 +Bacterial endocarditis 0.905604719764012 1.36105995777727 0.1734947424099697 1.0 0.8732992916209601 2 P10644 1 +Abnormal ilium morphology 0.471722995042332 1.360344851027773 0.1737208215195407 1.0 0.8732992916209601 20 P01889,P16278,Q04656,O95831,Q8TAA9,O00754 6 +Nephropathy 0.4714107624516695 1.3580331353920652 0.1744531701734377 1.0 0.8732992916209601 20 P06280,O76024,Q14108,P03886,P03915 5 +Abnormality of the phalanges of the toes 0.5274823325452421 1.3556901778921149 0.1751977658546544 1.0 0.8732992916209601 14 Q7LGA3,O75844,Q8WVQ1 3 +Oromandibular dystonia 0.8419672131147531 1.3547637670654065 0.1754928340196466 1.0 0.8732992916209601 3 Q15043,Q99720 2 +Abnormality of the cerebrospinal fluid 0.3965354042897031 1.352694521072302 0.1761532415161941 1.0 0.8755866021928699 139 Q15392,Q16625,P55011,P39210,P51798,Q7KZN9,Q9Y6M9,Q9P0J0,Q99519,P07602,P53701,Q15526,P07237,Q9H9S5,P04062,P40855,Q9HC21,O95831,Q8TAA9,O00754,Q9H490,P07942,P03886,P03915,P10644,Q9BXW9,Q6NUK1,O96000,P00403,Q86Y39,O43676,P23786,O43505,O95169,Q9NZJ7,P21964,P08236,P11166,P16435,P48651,O95202,P13073 42 +Depletion of mitochondrial dna in muscle tissue 0.8413083537283337 1.3521351180176502 0.1763320948270488 1.0 0.8755866021928699 3 P12235 1 +Preaxial hand polydactyly 0.6237945362682522 1.3434563670484267 0.1791242454987345 1.0 0.8813633520693414 7 O95202,Q9UHX1 2 +Abnormal lung lobation 0.5045503405378818 1.341407485169131 0.1797881886618795 1.0 0.8813633520693414 16 Q5SZK8,P21964,Q9UHX1 3 +Temperature instability 0.579594650915916 1.3400996231774764 0.1802129585884819 1.0 0.8820001291582289 9 Q9HC21,P07602,Q9NZJ7 3 +Abnormal elasticity of skin 0.4226455658619171 1.339412999615354 0.1804362597529272 1.0 0.8820001291582289 63 P10644,P04062,O75844,O75787,Q9UHX1,Q9Y487,Q9BV10,Q04656,Q15555,Q6NUK1,O96000,P38435,Q15904,O00754,Q9NWM8,Q9Y4P3,P36543 17 +Platyspondyly 0.470297052327569 1.339242685572931 0.1804916804520633 1.0 0.8820001291582289 34 Q14739,P16278,P04066,Q04656,Q6NUK1,O95831,P08236,O00754,Q8WVQ1,Q96HY6 10 +Thickened calvaria 0.5786573936355506 1.3350481695159122 0.1818605814809026 1.0 0.8827847324356265 9 P16278,Q7RTS9,O00754 3 +Aplasia hypoplasia of the nasal bone 0.8367554115497007 1.3339709188624096 0.1822133874370466 1.0 0.8827847324356265 3 P10644 1 +Diaphyseal thickening 0.8367213114754061 1.3338348810856422 0.1822579766867615 1.0 0.8827847324356265 3 P08236,Q14739 2 +Prolonged neonatal jaundice 0.4919420171503508 1.3327617042971782 0.182610016757345 1.0 0.8827847324356265 17 Q15904,O15118,Q04656,P61916 4 +Adrenal hyperplasia 0.686710386000216 1.332649775908859 0.1826467622522196 1.0 0.8827847324356265 5 P10644,P16435 2 +Abnormal glycosylation 0.4685862197592307 1.332365810942911 0.1827400110355836 1.0 0.8827847324356265 21 O75787,Q9Y487,Q9BT22,Q10471,Q8N511,Q15904,Q2TAA5,P36543 8 +Phenotypic variability 0.3593530155557989 1.3317442683799554 0.1829442371406675 1.0 0.8827847324356265 94 Q70HW3,O95470,P07602,Q15526,Q9H9S5,P56192,P03886,Q6P4A7,Q13510,P03915,O14979,P00403,P17900,Q9NZJ7,P00374,P09622,Q92733,P11166,Q9H061,O60313,Q8WVQ1 21 +Vegetative state 0.8360771035528989 1.331264920798623 0.1831018564018902 1.0 0.8827847324356265 3 P07602 1 +Progressive peripheral neuropathy 0.8360771035528989 1.331264920798623 0.1831018564018902 1.0 0.8827847324356265 3 P07602 1 +Impaired distal tactile sensation 0.734112305020016 1.3298185950268706 0.1835780477183117 1.0 0.8827847324356265 4 P39210,O15269 2 +Dyschromatopsia 0.6201324390645586 1.3251747685873052 0.1851131918941468 1.0 0.8827847324356265 7 Q9H061,O60313,O00429,Q9H6K4 4 +Cerebral cortical atrophy 0.3595008370898766 1.3223358207593054 0.1860563497247118 1.0 0.8827847324356265 95 P04062,Q13501,Q16625,Q15042,P55011,O75503,O76024,Q9Y619,Q92673,Q9H9S5,Q7LGA3,O00754,Q92581,P03886,Q5KU26,P05067,Q9Y4P3,P03915 18 +Abnormality of the knee 0.3507704056439683 1.3200832185609623 0.1868072349921936 1.0 0.8827847324356265 85 Q13510,P21964,P16278,Q04656,P51798,Q9NX62,O95831,P08236,Q86XL3,Q9Y619,O00754,Q8WVQ1,Q7LGA3,P23786,Q9Y4P3,Q96HY6,Q96PU5 17 +Abnormal retinal vascular morphology 0.4465735033677329 1.3196084126561591 0.1869657926446213 1.0 0.8827847324356265 52 P21964,P16278,P06865,P04439,Q15555,P10619,P07686,P38435,Q99519,P07602,P17900,P03886,Q13510,Q9NZJ7 14 +Abnormal endocrine physiology 0.683686669000424 1.3190132820105132 0.1871646721332087 1.0 0.8827847324356265 5 Q13423 1 +Peripheral demyelination 0.5010761074923549 1.31832636162112 0.1873944198943395 1.0 0.8827847324356265 16 P03915,P07602,Q15526,P03886,Q9NZJ7 5 +Osteopetrosis 0.8327868852459049 1.3181399396857674 0.18745680658132 1.0 0.8827847324356265 3 P48651,P51798 2 +Follicular hyperkeratosis 0.5966668106162341 1.3160397400041035 0.1881607047260947 1.0 0.8827847324356265 8 Q07954,Q9NWM8,Q14574 3 +Abnormal brain n acetyl aspartate level by mrs 0.832214464931266 1.3158566629220754 0.1882221567082163 1.0 0.8827847324356265 3 P07602 1 +Reduced brain n acetyl aspartate level by mrs 0.832214464931266 1.3158566629220754 0.1882221567082163 1.0 0.8827847324356265 3 P07602 1 +Abnormal brain choline level by mrs 0.832214464931266 1.3158566629220754 0.1882221567082163 1.0 0.8827847324356265 3 P07602 1 +Retrocollis 0.8318032786885265 1.314216551970924 0.1887733399198063 1.0 0.8827847324356265 3 Q99720,P35637 2 +Type ii transferrin isoform profile 0.8941330711242231 1.3136763374094993 0.1889551472358221 1.0 0.8827847324356265 2 Q15904 1 +Muscle abnormality related to mitochondrial dysfunction 0.4674165014044479 1.3127979488374315 0.1892510413992325 1.0 0.8827847324356265 33 P12235,Q9UBX3,O96000,Q9Y6M9,Q96CU9,P00403,Q86Y39,O43676,O60313,Q15526,Q9Y2R0,P03886,P03915 13 +Hip osteoarthritis 0.8938053097345131 1.312323841389171 0.1894108911925514 1.0 0.8827847324356265 2 P51798 1 +Spinal deformities 0.7297474581829925 1.3114404250193503 0.1897090087612563 1.0 0.8827847324356265 4 P53007,Q9H9S5,Q9Y5P6 3 +Abnormality of the ribs 0.4222561434411352 1.3070610672781529 0.1911919723925184 1.0 0.8827847324356265 62 P54802,O75844,Q14739,Q9UHX1,Q9BV10,P16278,Q04656,P51798,Q7RTS9,O95831,Q8TAA9,Q9Y619,P16435,O00754,P15586,O95202,P07237,Q96HY6 18 +Lissencephaly 0.450487269129914 1.3065404263389662 0.1913688406570624 1.0 0.8827847324356265 49 Q16625,Q15042,Q9Y487,P98155,Q9BV10,Q9HC21,P23786,Q86XL3,P07942,O43505,Q9H9S5 11 +Congenital craniofacial dysostosis 0.8911832186168519 1.3015068502409328 0.1930850212696673 1.0 0.8827847324356265 2 P10644 1 +Absent nipple 0.8911832186168465 1.3015068502409115 0.1930850212696746 1.0 0.8827847324356265 2 P10586 1 +Hypotriglyceridemia 0.8908554572271392 1.300155108216578 0.1935478131774393 1.0 0.8827847324356265 2 Q9Y6B6 1 +Hypolipidemia 0.8908554572271392 1.300155108216578 0.1935478131774393 1.0 0.8827847324356265 2 Q9Y6B6 1 +Anteriorly placed anus 0.5506464659315468 1.2988342803612072 0.1940008074351782 1.0 0.8827847324356265 10 P53701,P16435,P48651,Q6NUK1 4 +Abnormal vitreous humor morphology 0.5927337092498378 1.29561200300839 0.1951091917304575 1.0 0.8827847324356265 8 P04439 1 +Fatigue 0.3497742335190502 1.294782447631884 0.1953952886425363 1.0 0.8827847324356265 86 Q13501,Q70HW3,Q9Y6X9,O00592,P07602,P04062,P17612,Q07021,P06280,Q68CQ7,Q5HYI8,Q9NZ08,Q53H12,P10644,Q13423,P01889,Q04656,P49815,Q9BZK7,Q9NZJ7,Q14739,P12235,P35637,Q15165,O00429,P15529,O60313,Q92804,Q4J6C6 29 +Renal steatosis 0.8267389877549268 1.2940191727722206 0.1956587983313273 1.0 0.8827847324356265 3 P04114 1 +Abnormal iliac wing morphology 0.5257913873247467 1.288605767184549 0.1975351774298528 1.0 0.8827847324356265 13 P16278,O95831,Q04656,Q8TAA9 4 +Ulnar deviation of the wrist 0.7239871835572825 1.2871768468013391 0.1980326553407552 1.0 0.8827847324356265 4 P16278,Q9BV10 2 +Upper airway obstruction 0.7236600344780436 1.2857985337895197 0.1985133820736129 1.0 0.8827847324356265 4 O75844,Q96HY6 2 +Polyneuropathy 0.4961390018844239 1.285466110021173 0.1986294521345608 1.0 0.8827847324356265 16 P04066,Q9HC21,O95831,O60313,P07602,P03886,Q9NZJ7 7 +Abnormal thyroid stimulating hormone level 0.8245901639344142 1.2854510569452569 0.1986347092848643 1.0 0.8827847324356265 3 P10644,P16870 2 +Decreased facial expression 0.4645956197275537 1.2843792081239425 0.199009304320096 1.0 0.8827847324356265 29 P04062,O75787,P12235,Q04656,O00592,Q9H9S5 6 +Abnormal systemic blood pressure 0.3566579095858178 1.2839297103231797 0.1991665506060422 1.0 0.8827847324356265 95 O75844,P04114,P07602,Q96J02,P04062,P06280,Q8TAA9,P03886,P01130,P10644,Q13423,P01889,P38571,Q04656,P07686,P00533,Q9NZJ7,P21964,P42892,P15529,P16435 21 +Abnormal atrioventricular valve physiology 0.4524012284690233 1.2828799971405396 0.1995341217593009 1.0 0.8827847324356265 46 P10644,P04062,O75844,P19022,P01889,P06280,Q6NUK1,Q15904,P04114,Q9NZ08,P53701,O00754,Q15526,Q9Y4P3,P01130,P36543 16 +Morphological abnormality of the corticospinal tract 0.5157121427337843 1.2821309205214195 0.1997967238202207 1.0 0.8827847324356265 14 Q9Y4P3,Q13501,P35637 3 +Inability to walk 0.3470695635160836 1.2815897800771647 0.1999865871550044 1.0 0.8827847324356265 84 Q96N66,O00592,Q99519,Q15043,Q9H9S5,Q9NVI7,Q99720,Q6DD88,Q13510,O14949,O75787,Q7RTS9,Q92581,P12235,P35637,Q96C86,O75503,O43292,P11166,O15269,P07196 21 +Redundant neck skin 0.5897304421369479 1.2799977870821762 0.200545914181812 1.0 0.8827847324356265 8 P36543,Q9Y487 2 +Hyperconvex nail 0.5893174052145014 1.277849337777785 0.2013025542261233 1.0 0.8827847324356265 8 O95202,Q9Y619,P42892 3 +Bilateral tonic clonic seizure with focal onset 0.8852835136021124 1.2771893529919742 0.2015354049557447 1.0 0.8827847324356265 2 P07602 1 +Hyperesthesia 0.8852835136021124 1.2771893529919742 0.2015354049557447 1.0 0.8827847324356265 2 P07602 1 +Abducens palsy 0.8852835136021124 1.2771893529919742 0.2015354049557447 1.0 0.8827847324356265 2 P07602 1 +Atrophic scars 0.6278508250534998 1.2752521369652288 0.2022200128343454 1.0 0.8827847324356265 6 Q07954,P53634 2 +Abnormality of facial musculature 0.3663383729226888 1.2746607795618212 0.2024293345231151 1.0 0.8827847324356265 78 Q15526,P04062,P12235,Q13501,Q9UHX1,P40855,O75787,P51798,O00592,O60313,Q9H9S5,O00754,P10253,Q13510 14 +Neurodegeneration 0.4632734060210238 1.2744600377046382 0.2025004266303152 1.0 0.8827847324356265 30 Q13501,P35637,Q8NHS3,Q15165,Q68CQ7,P08236,P17900,Q6DKK2 8 +Hepatic encephalopathy 0.8218063372364217 1.2743529196497707 0.2025383696007341 1.0 0.8827847324356265 3 P09622 1 +Perimembranous ventricular septal defect 0.6276197161031415 1.2741308079758844 0.2026170617012548 1.0 0.8827847324356265 6 Q9UHX1 1 +Acanthocytosis 0.7207668844928562 1.2736082695007915 0.2028022800645663 1.0 0.8827847324356265 4 P04114 1 +Focal segmental glomerulosclerosis 0.462197622574362 1.2730951046209713 0.2029842958818393 1.0 0.8827847324356265 24 Q12769,Q8N1F7,Q92621,Q8NFH4,P00403,O95470,O75431,Q14108,Q96J84,Q96AX1,P03886,P03915 12 +Conical tooth 0.6271334374753931 1.2717712310367577 0.2034544134747098 1.0 0.8829117679763278 6 P17612,Q9Y487 2 +Optic neuropathy 0.4603029493121571 1.2704931099434098 0.2039090355974935 1.0 0.8840529898601858 21 O96000,Q9Y6M9,Q9P0J0,P04114,Q86Y39,O43676,P03886,P01130,P03915 9 +Positive romberg sign 0.6087733230792125 1.2683533171925885 0.2046718047051929 1.0 0.8858516504532798 7 P07196,Q8IV08 2 +Abnormality of the synovia 0.3460687519991545 1.267952298710955 0.2048149858240646 1.0 0.8858516504532798 84 O75844,Q96A33,Q9BXW9,Q9UHX1,P55011,Q9Y487,P16278,Q04656,Q6NUQ1,P08236,P16435,Q8WVQ1,O95202,Q9H9S5,P36543 15 +Venous insufficiency 0.6085384934950409 1.267176920852488 0.2050920361335579 1.0 0.8858516504532798 7 Q04656,P21964 2 +Joint dislocation 0.3519581634008262 1.2661490516897926 0.2054597239590412 1.0 0.886518741628606 91 P10644,O75844,Q96A33,P21964,Q9UHX1,Q9Y487,Q04656,P51798,Q9NX62,Q9Y619,Q8WVQ1,O95202,Q9Y4P3,Q9H9S5,Q96PU5,P36543 16 +Abnormality of the common coagulation pathway 0.4821162879534692 1.2651347833567712 0.2058230158864593 1.0 0.886518741628606 17 P10644,P15529,P38435,Q9BV10 4 +Elevated hepatic transaminase 0.355024203592801 1.2618080375478589 0.2070178693001225 1.0 0.8881907163686776 95 Q9HC07,Q16625,P39210,Q8N511,Q2TAA5,P56192,P40855,Q5HYI8,Q9Y619,Q9Y6B6,Q13510,O75787,P01889,P38571,Q15904,P23786,P10253,Q14739,P12235,Q9BV10,P09622,Q6NUQ1,P15529,Q5XKP0 24 +Cataplexy 0.7178225323196001 1.261200479865657 0.2072366258090554 1.0 0.8881907163686776 4 O15118 1 +Abnormal lumbar spine morphology 0.5438992467364099 1.2608401554942112 0.2073664429935109 1.0 0.8881907163686776 10 P08236,O00754 2 +Abnormal circulating iga level 0.5281889642933353 1.2532460132637595 0.2101161890777245 1.0 0.89621453443121 12 Q15904,Q9BV10 2 +Communicating hydrocephalus 0.6685239523502121 1.2505389711071475 0.2111027284909359 1.0 0.89621453443121 5 P11166,O00754 2 +Vaginal atresia 0.878728285807945 1.250207516391021 0.211223751807142 1.0 0.89621453443121 2 Q5SZK8 1 +Aplasia hypoplasia of toe 0.4599665472066176 1.24932772114219 0.2115452327684623 1.0 0.89621453443121 31 P10644,P13073,Q9UHX1,Q9NX62,Q7LGA3,O95202,Q13510 7 +Abnormality of the wrist 0.4593950653470678 1.2447966330151736 0.2132065141161516 1.0 0.8987467687621064 31 O75844,Q9BV10,P16278,Q04656,Q7RTS9,O95831,P16435,Q8WVQ1,Q13510 9 +Coarse facial features 0.4048219153618907 1.2424489925745623 0.2140709489806065 1.0 0.8987467687621064 66 P54802,P16278,P04066,P10619,P06280,P07686,P08236,Q99519,O00754,Q7LGA3,Q96A33,P15586 12 +Prolonged partial thromboplastin time 0.6206735372427831 1.2404039756354974 0.2148260112603219 1.0 0.8987467687621064 6 Q9BV10 1 +Myelomeningocele 0.7122719693790904 1.2378064580951498 0.2157878332622513 1.0 0.8987467687621064 4 Q5SZK8 1 +Cardiac conduction abnormality 0.4582158327618125 1.236913375825884 0.216119243695362 1.0 0.8987467687621064 32 Q15526,P19022,P36543,P06280,P23786,P00403,Q07954,P0DP25,Q9H490,P03886,P50402,P03915 12 +Complete atrioventricular canal defect 0.8121311475409676 1.2358032384095845 0.2165317109532556 1.0 0.8987467687621064 3 Q9UHX1,P17612 2 +Abnormal upper limb bone morphology 0.3546924574047594 1.2345733904143132 0.2169893173661248 1.0 0.8987467687621064 97 O75844,P55011,P51798,Q7LGA3,Q6DD88,P53634,P10644,Q9BXW9,Q9UHX1,P16278,Q04656,Q6NUK1,Q14739,Q9BV10,Q9NX62,P08236,P16435,Q8WVQ1,O95202,Q9Y4P3 20 +Generalized muscle weakness 0.4570709359002415 1.232602154316845 0.2177242327887756 1.0 0.9007729917978672 34 Q13501,P35637,P12235,Q15165,Q68CQ7,O95831,Q9H9S5,P10253 8 +External ear malformation 0.4876371665458142 1.2287245544480652 0.2191750967226988 1.0 0.9043423266384704 16 O75381,Q9BXW9,P40855,Q5SZK8,Q15555,P08754 6 +Abnormal metabolic brain imaging by mrs 0.4531187376241651 1.2278816484980428 0.2194913994629845 1.0 0.9048380926923572 19 Q9NZJ7,P35610,P00403,P07602,Q15526,P03886,O95169,P03915 8 +Xanthomatosis 0.7097863632590582 1.2273295337564794 0.2196987595431863 1.0 0.9048842658684986 4 P04114 1 +Incoordination 0.4002697431376976 1.2253416979044367 0.2204465038048964 1.0 0.906047464398011 67 P04062,Q13501,O75787,P12235,O75503,O14773,Q9Y619,P07602,O00754,Q01105,Q6DKK2,Q9H9S5,Q13510,Q9NZJ7 14 +Increased circulating lactate dehydrogenase concentration 0.4968501141575819 1.2228526315872077 0.2213853623163124 1.0 0.906047464398011 15 P15529,P38571,P10253 3 +Aplasia hypoplasia involving bones of the lower limbs 0.3452832126028558 1.2218555653385483 0.2217622514663821 1.0 0.906047464398011 87 P10644,P13073,Q9UHX1,Q9BV10,Q04656,Q9NX62,Q10471,O95831,Q9Y619,P15260,Q8WVQ1,Q7LGA3,O95202,Q96HY6,Q96A33,Q13510 16 +Thoracic kyphoscoliosis 0.6168335362569117 1.2217403626465189 0.2218058274703667 1.0 0.906047464398011 6 O75844 1 +Abnormality of the supraorbital ridges 0.4531349744837855 1.216762474191568 0.2236946014586955 1.0 0.906047464398011 21 O75381,P40855,Q6NUK1,Q92889,P50542,Q99519,P16435,Q08J23 8 +Neuroinflammation 0.8072667594723555 1.216437893043503 0.223818156436576 1.0 0.906047464398011 3 Q9NZ08 1 +Pleuritis 0.8072667594723555 1.216437893043503 0.223818156436576 1.0 0.906047464398011 3 Q9NZ08 1 +Orchitis 0.8072667594723555 1.216437893043503 0.223818156436576 1.0 0.906047464398011 3 Q9NZ08 1 +Abnormal full field electroretinogram 0.5981790355546306 1.2152194776231953 0.2242823935484135 1.0 0.906047464398011 7 Q15555,P50897 2 +Abnormal light and dark adapted electroretinogram 0.5981790355546306 1.2152194776231953 0.2242823935484135 1.0 0.906047464398011 7 Q15555,P50897 2 +Acquired abnormal hair pattern 0.6154817619339068 1.2151674460985809 0.224302233761658 1.0 0.906047464398011 6 O75844 1 +Progressive sensorineural hearing impairment 0.528632196762398 1.2122708025410214 0.2254087365817203 1.0 0.9078195666027378 11 O76024,P03886,O60313,P03915 4 +Encephalocele 0.4848501935979442 1.210084665094698 0.2262464068356995 1.0 0.909124281126378 16 P14543,Q5SZK8,O43505,Q9H9S5 4 +Biliary cirrhosis 0.6141000658833287 1.2084475834759214 0.226875146230522 1.0 0.9092745869343164 6 P09601 1 +Chordee 0.6138274426764472 1.2071215151175607 0.2273853502295999 1.0 0.9105283165009936 6 P16435,P53701 2 +Abnormal umbilicus morphology 0.4098545206927393 1.206542396468741 0.2276084221752794 1.0 0.9106310940976272 63 O75844,Q9BXW9,P98164,Q14739,Q96JJ3,P21964,Q9Y487,Q04656,Q5SZK8,Q6NUK1,Q15555,P08236,Q99519,O00754,Q9Y4P3 15 +Acetabular dysplasia 0.5542105261605804 1.2027461241478494 0.2290745790969075 1.0 0.9156225390814896 9 P16278 1 +Tissue ischemia 0.4495621243237055 1.2014401429909507 0.2295805122791807 1.0 0.9156225390814896 19 O75844,P01889,P06280,Q9NZ08,P05067 5 +Calcinosis 0.6575676977739382 1.2009891156470331 0.2297554234632448 1.0 0.9156225390814896 5 O75844 1 +Abnormal heart valve morphology 0.3749027022502 1.1967044568734273 0.2314217692702889 1.0 0.9194302393091012 74 P10644,P04062,O75844,Q9BXW9,P21964,Q9UHX1,P01889,P16278,P51798,P06280,Q6NUK1,P08236,P53701,O95202,Q9Y4P3,Q96PU5,P36543 17 +Left ventricular systolic dysfunction 0.8022877533493283 1.196630285514216 0.2314506906276152 1.0 0.9194302393091012 3 P12235 1 +Turricephaly 0.5318194201871626 1.1926069513810715 0.2330233421441887 1.0 0.9195068244794524 10 P16435,P21964,Q6NUK1 3 +Low frustration tolerance 0.5520636810158317 1.1910838815251683 0.2336206568732191 1.0 0.9195068244794524 9 Q9UHX1 1 +Lower limb spasticity 0.3812446614975257 1.1902809930685696 0.2339359687144488 1.0 0.9195068244794524 72 Q7KZN9,Q96CU9,Q9P0J0,Q99519,P07602,Q15526,P04062,P56192,Q99720,O95831,Q9Y619,O00754,P07942,O75787,Q6DKK2,Q9NZJ7,P35637,P11166,O60313,Q5XKP0,O00400 21 +Parkinsonism with favorable response to dopaminergic medication 0.5309966290358707 1.1879504883257304 0.2348529167195723 1.0 0.9195068244794524 10 P04062,P07602 2 +Transient ischemic attack 0.5927454891724213 1.187925117121524 0.2348629131230297 1.0 0.9195068244794524 7 P06280 1 +Premature loss of primary teeth 0.7000931094201137 1.1864736157247928 0.2354353149624573 1.0 0.9195068244794524 4 P53634 1 +Intestinal pseudo obstruction 0.5305970446826285 1.1856887220204575 0.2357452499904349 1.0 0.9195068244794524 10 Q5HYI8,P03886,P03915 3 +Calvarial skull defect 0.5920820125931143 1.1845905191225448 0.236179387402299 1.0 0.9195068244794524 7 O95202,Q5SZK8 2 +Genu varum 0.5235200002382128 1.1826245932993376 0.2369579612599777 1.0 0.9195068244794524 11 Q9Y619,Q96HY6,Q8WVQ1 3 +Aortic regurgitation 0.4507376749677438 1.182579181269786 0.2369759673867015 1.0 0.9195068244794524 25 O75844,Q9UHX1,P01889,Q9NZ08,O00754,Q96PU5 6 +Patchy changes of bone mineral density 0.6989216208701462 1.1815366286566396 0.2373896113619384 1.0 0.9195068244794524 4 Q13501 1 +Cerebral dysmyelination 0.5913867941465467 1.181096004947216 0.2375645868288427 1.0 0.9195068244794524 7 P07602 1 +Limb girdle muscle weakness 0.4498315211930772 1.178847680773718 0.2384588341307056 1.0 0.9195068244794524 24 P12235,O60313,P07602,Q9H9S5,Q9NZJ7 5 +Coronary artery atherosclerosis 0.6077683092095048 1.177636025771175 0.2389417411910281 1.0 0.9195068244794524 6 P04114 1 +Bladder diverticulum 0.5697754493135223 1.1759460747066284 0.2396164255443524 1.0 0.9195068244794524 8 Q04656,Q9Y4P3 2 +Absent brainstem auditory responses 0.6975407009109837 1.1757173718906304 0.2397078343614949 1.0 0.9195068244794524 4 P07196,O60313 2 +Ambiguous genitalia 0.4460055340736537 1.1749631246908947 0.2400094689980276 1.0 0.9195068244794524 19 P51809,Q5SZK8,P16435,Q8TAA9,P53701 5 +Tritanomaly 0.7967213114754093 1.174505297099585 0.2401926914671204 1.0 0.9195068244794524 3 O60313,Q9H6K4 2 +Anomalous trichromacy 0.7967213114754093 1.174505297099585 0.2401926914671204 1.0 0.9195068244794524 3 O60313,Q9H6K4 2 +Ankyloblepharon 0.5488191574520205 1.17344753353162 0.2406163850321021 1.0 0.9195068244794524 9 Q92889,Q5SZK8,O75569 3 +Abnormality of the posterior pituitary 0.5692777478521948 1.1733450833399215 0.240657450022568 1.0 0.9195068244794524 8 O76024,Q8WWQ0,Q9UHX1,Q99496 4 +Abnormality of the gallbladder 0.4495434914835567 1.1716000375832634 0.241357672982315 1.0 0.9195068244794524 34 P04062,P40855,P21964,P04066,P07602,O95202,Q96A33,Q9NZJ7 8 +Abnormality of the radioulnar joints 0.7957449255232871 1.1706268082895916 0.2417488166965899 1.0 0.9195068244794524 3 Q8WVQ1 1 +Radioulnar dislocation 0.7957449255232871 1.1706268082895916 0.2417488166965899 1.0 0.9195068244794524 3 Q8WVQ1 1 +Abnormal spermatogenesis 0.5063724363263453 1.170037268908816 0.2419859711506731 1.0 0.9195068244794524 13 P04062,P51809,Q9BXW9,Q13423,Q92889,P16435 6 +Hemianopia 0.5472795106428497 1.1650739498924352 0.2439890604592578 1.0 0.9228189337719062 9 P03886,P03915 2 +Accessory spleen 0.5881433200240351 1.1647877515223917 0.2441049180622991 1.0 0.9228189337719062 7 Q15904 1 +Cutaneous cyst 0.6495334245730435 1.1646325983939925 0.2441677426365265 1.0 0.9228189337719062 5 Q8TAA9,P49815 2 +Pelvic kidney 0.5671785121368139 1.1623718736856388 0.2450844430392869 1.0 0.9228189337719062 8 Q9Y4P3,Q9UHX1 2 +Abnormal circulating citrulline concentration 0.6489180694906719 1.161847631189368 0.2452973623922503 1.0 0.9228189337719062 5 Q9Y619,P03886 2 +Posteriorly rotated ears 0.3615027495829139 1.1610526807829835 0.245620476376998 1.0 0.9228189337719062 112 Q9HC07,Q7LGA3,Q96J02,Q9H9S5,P04062,P40855,Q9Y619,Q86UE8,Q9H490,P98164,Q9UHX1,Q15042,Q5SZK8,Q6NUK1,Q10471,P23786,O43505,P42892,Q15555,P16435,Q8WVQ1,O95202,P11233 23 +Gingival overgrowth 0.4487951807210654 1.1605430193734632 0.2458277893149194 1.0 0.9228189337719062 31 P10644,Q14739,P16278,P08236,Q99519,O00754 6 +Progressive spasticity 0.487230423629817 1.1604336907086168 0.2458722764770304 1.0 0.9228189337719062 15 P17900,P07602,Q9NZJ7 3 +Eeg with irregular generalized spike and wave complexes 0.7918032786885253 1.1549772664145397 0.2480997361275703 1.0 0.9274587380522544 3 Q9NQZ5,P11166 2 +Agenesis of corpus callosum 0.3367596076340838 1.1523248599351668 0.2491876050765988 1.0 0.9289361018115088 83 P55011,P53701,Q7LGA3,Q9H9S5,P19022,Q9HC21,P03886,P03915,Q9BXW9,P98164,Q9UHX1,Q15042,P00403,P23786,O43505,P78318,Q86XL3,P48651,O95202 19 +Focal cortical dysplasia 0.7905479525904991 1.149996005415431 0.2501455165377619 1.0 0.9289361018115088 3 P42345 1 +Abnormal greater sciatic notch morphology 0.6017292169713644 1.1482264564360434 0.2508750902135959 1.0 0.9289361018115088 6 P08236,Q96HY6 2 +Low plasma citrulline 0.8538184201901009 1.1481384328249766 0.2509114205196487 1.0 0.9289361018115088 2 P03886 1 +Retinal arterial tortuosity 0.8538184201901009 1.1481384328249766 0.2509114205196487 1.0 0.9289361018115088 2 P03886 1 +Leber optic atrophy 0.8538184201901009 1.1481384328249766 0.2509114205196487 1.0 0.9289361018115088 2 P03886 1 +Multiple glomerular cysts 0.8538184201901009 1.1481384328249766 0.2509114205196487 1.0 0.9289361018115088 2 P03886 1 +Ankylosis 0.6453636455019738 1.1457606916084753 0.2518941838414625 1.0 0.9310800240870728 5 O75844,P16435,P48651 3 +Abnormal tongue physiology 0.4750366680831006 1.144312694193213 0.2524939806517823 1.0 0.9324322351731524 16 P04350,P08754,O95831,Q16637,P10253,Q13510 6 +Abnormal cardiac test 0.5020280820351706 1.1434148133446622 0.2528664049862592 1.0 0.9324322351731524 13 Q99519,P12235,P10253 3 +Recurrent gastroenteritis 0.7876559683216617 1.1385257336853756 0.2549010196417136 1.0 0.9342775475278065 3 O00754 1 +Color vision defect 0.5158931246411795 1.13831951758882 0.2549870870014108 1.0 0.9342775475278065 11 O00429,Q9Y6X9,O00592,Q9H061,O60313,Q9H6K4 6 +Abnormal heart rate variability 0.6885056184749345 1.1376557876929256 0.2552642417439172 1.0 0.9345507517180084 4 P07602 1 +Elevated gamma glutamyltransferase level 0.688001379489847 1.1355324393340036 0.2561522980502664 1.0 0.9357417975913908 4 Q5XKP0 1 +Decreased light and dark adapted electroretinogram amplitude 0.7868733499284775 1.1354230368699536 0.256198111935384 1.0 0.9357417975913908 3 P50897 1 +Peters anomaly 0.7865037140361447 1.1339578179015997 0.2568122424479919 1.0 0.9357621440857716 3 Q9H9S5 1 +Moderately reduced visual acuity 0.785587462535827 1.130326417719931 0.2583387068510248 1.0 0.9367979898023666 3 O60313 1 +Enlarged thorax 0.4399249128900672 1.1296210626565992 0.2586359319136067 1.0 0.9367979898023666 19 O75844,Q14739,P17612,P04066,Q7RTS9,P08236 6 +Wide pubic symphysis 0.849229760734203 1.1294341461076154 0.2587147351918726 1.0 0.9367979898023666 2 Q5SZK8 1 +Abnormality of the glenoid fossa 0.8492297607341983 1.1294341461075983 0.2587147351918797 1.0 0.9367979898023666 2 Q9Y619 1 +Abnormal acetabulum morphology 0.4396601314551622 1.12764466626692 0.2594700150495721 1.0 0.9367979898023666 19 P16278,P08236,Q6NUQ1,Q8WVQ1 4 +Ovarian cyst 0.4815988298917931 1.1238102884319896 0.2610935158778056 1.0 0.9367979898023666 15 P10644,P16435,P31751 3 +Emg chronic denervation signs 0.4988170301259747 1.1237186348291022 0.261132408386352 1.0 0.9367979898023666 13 P39210,P07602,Q13510,Q9NZJ7 4 +Abnormality of the clitoris 0.4407124907857558 1.1232897907068615 0.2613144383470576 1.0 0.9367979898023666 21 P51809,O75381,P40855,Q15042,P16435,Q9Y619,P53701,Q9UBM7,Q9UNW1,Q9NP72,O75419 11 +Hypertrophic cardiomyopathy 0.3489807772900806 1.122984841871029 0.2614439322688295 1.0 0.9367979898023666 100 Q7KZN9,Q9Y6M9,Q9P0J0,P53701,Q15526,P54802,Q9NVI7,P06280,P15586,P03886,P03915,Q9BXW9,Q13423,P01889,P16278,O96000,P00403,Q86Y39,O43676,P10253,P50402,P12235,P09622,Q9H061,O60313,Q5XKP0,Q9Y4P3 27 +High frequency sensorineural hearing impairment 0.6846037113454 1.121227784508852 0.2621909157916513 1.0 0.9367979898023666 4 O75844,Q13510 2 +Aphasia 0.4413005077208203 1.1191751391378142 0.2630654292636445 1.0 0.9367979898023666 38 Q13501,P55011,P21964,P00403,P53701,Q92673,Q7LGA3,P03886,P05067,P03915 10 +Broad femoral neck 0.6839800149910573 1.1186025296083884 0.2633097438232821 1.0 0.9367979898023666 4 Q8WVQ1 1 +Limited extraocular movements 0.5386545611869632 1.1181184961872996 0.2635163878194861 1.0 0.9367979898023666 9 O43819,O95169,Q15526 3 +Somatic sensory dysfunction 0.3436199784711833 1.1178464083540167 0.2636325969244111 1.0 0.9367979898023666 94 P39210,Q8IV08,P07602,P05067,P54802,P56192,Q6DD88,P06280,O95831,Q9NZ08,Q9Y619,Q9Y6B6,P01889,Q04656,P07686,Q9NZJ7,O14773,P11166,O15269,P07196,P51149,O00400 22 +Acne 0.4804478806335405 1.116318961436346 0.2642856280203944 1.0 0.9367979898023666 15 Q9NZ08,P21964,Q92542 3 +Mitochondrial myopathy 0.4420806368567141 1.1159799269413762 0.2644307269401345 1.0 0.9367979898023666 25 P12235,O96000,Q9Y6M9,Q96CU9,P00403,Q86Y39,O43676,O60313,P03886,P03915 10 +Abnormality of the metacarpal bones 0.4386788587846246 1.1153516275375042 0.2646997697196844 1.0 0.9367979898023666 41 P10644,Q9BXW9,Q14739,P16278,Q6NUK1,P51798,Q7RTS9,Q9NX62,P08236,P16435,Q8WVQ1,O95202 12 +Short femur 0.594817513958303 1.1145480147645856 0.2650441579610145 1.0 0.9367979898023666 6 Q9UHX1 1 +Abnormality of the odontoid process 0.5780198925121697 1.113842985575295 0.2653465523385301 1.0 0.9367979898023666 7 P16278,P08236,O95831 3 +Slow decrease in visual acuity 0.5378373054593348 1.113665506296192 0.265422712480315 1.0 0.9367979898023666 9 Q99496,O00429,O75306,P03886,P03915 5 +Atlantoaxial instability 0.8449688626679774 1.1120982398348234 0.26609591345726 1.0 0.936902854856558 2 Q7RTS9 1 +Rimmed vacuoles 0.4886575757910837 1.1118670763478964 0.2661953064015101 1.0 0.936902854856558 14 O14979,Q13501 2 +Visual fixation instability 0.7808785086796743 1.1116768474118754 0.2662771179549184 1.0 0.936902854856558 3 Q5KU26 1 +Flaring of rib cage 0.7807664504528543 1.1112333336568017 0.2664679266359862 1.0 0.936902854856558 3 P16278 1 +Nephrotic syndrome 0.4415156750324742 1.1086117216608689 0.267597719262211 1.0 0.9387287292445472 26 P51809,P56192,Q9BT22,P06280,O95470,Q14108,Q96J84 7 +Recurrent pancreatitis 0.6811328993675555 1.1066210819376678 0.2684577885670656 1.0 0.939805393579688 4 P03886,P03915 2 +Aplasia hypoplasia of the patella 0.6365814029518659 1.1060160869875455 0.2687195564993732 1.0 0.939805393579688 5 Q9Y619 1 +Macrovesicular hepatic steatosis 0.5926062936661838 1.103770458074941 0.2696927228381205 1.0 0.9414924151902492 6 P39210,Q5XKP0 2 +Diffuse cerebral atrophy 0.4873258390103726 1.1034527394702096 0.2698306044549663 1.0 0.9414924151902492 14 Q9NVC6,O75787,P16278,O00429,P07602,Q9NZJ7 6 +Convex nasal ridge 0.4380780702732783 1.103418360952317 0.2698455267369355 1.0 0.9414924151902492 21 O95202,Q96J02,O75844,Q04656 4 +Type i diabetes mellitus 0.4954451228280293 1.1030203906320053 0.2700183102745934 1.0 0.9414924151902492 13 Q96J02,P03886,P03915 3 +Abnormal response to endocrine stimulation test 0.7781091642656919 1.1007202076542686 0.2710184485759557 1.0 0.941687124547794 3 Q13423 1 +Abnormal sacrum morphology 0.4410277987486562 1.100513303572932 0.2711085364288113 1.0 0.941687124547794 28 Q14739,P01889,P04066,Q8TAA9,P53701,O95202 6 +Gray matter heterotopia 0.4411401322991234 1.1001386434579847 0.2712717189407301 1.0 0.941687124547794 29 Q6NUK1,Q86XL3,Q2TAA5,P07942,O43505,Q9H9S5,Q96PU5 7 +Neck muscle weakness 0.4867266198952368 1.0996659055137887 0.2714777150637615 1.0 0.941687124547794 14 Q86U42,P35637,Q99720,Q9Y6X9,Q9Y5P6,P53007,P07602,Q9NZJ7 8 +Flat face 0.4394181543609209 1.0991394287477256 0.2717072540154159 1.0 0.941687124547794 24 P40855,Q9Y487,Q15555,Q9NX62,P08236,O00754 6 +Sensory axonal neuropathy 0.5021495063714579 1.0981282003030488 0.2721485128719836 1.0 0.9418012677257768 12 Q15067,Q6DD88,O95831,Q8IV08 4 +Lower extremity joint dislocation 0.3484984240951908 1.0960302718331811 0.2730655270684123 1.0 0.9428348209612504 79 O75844,Q96A33,P21964,Q9UHX1,Q9Y487,Q04656,Q9NX62,Q8WVQ1,O95202,Q9Y4P3,Q9H9S5,Q96PU5,P36543 13 +Decreased circulating iga level 0.5743922747491846 1.09557519808325 0.2732647204910452 1.0 0.9428348209612504 7 Q15904,Q96J02 2 +Pain insensitivity 0.6333943219905899 1.0915962035036586 0.2750106255913465 1.0 0.947658351628725 5 P39210,O15269 2 +Rhizomelia 0.5010326514271426 1.0914529969609277 0.2750736034751491 1.0 0.947658351628725 12 Q15392,Q14739,Q7RTS9,Q9BV10 4 +Abnormality of the autonomic nervous system 0.4126758077331204 1.0909419072351645 0.2752984454616041 1.0 0.9477251708316266 57 P04062,P21964,P42892,Q6DD88,Q04656,P06280,P07686,O76024,O00592,P07602,O15269,P0DP25,Q9NZJ7 13 +Thick cerebral cortex 0.676963894754377 1.0890853148329378 0.2761162651503572 1.0 0.9498317159870232 4 Q9Y487 1 +Aplasia hypoplasia of the proximal phalanges of the hand 0.7740128241026005 1.0845298593351076 0.2781299352222715 1.0 0.952925602301064 3 Q9BXW9 1 +Abnormality of the alveolar ridges 0.552222738919526 1.0840949025951372 0.2783227227243408 1.0 0.952925602301064 8 Q15392,O43924,P53634 3 +Protuberant abdomen 0.631666843179456 1.0837815306172895 0.2784616761113883 1.0 0.952925602301064 5 P38571,P04062,Q7RTS9 3 +Elevated circulating long chain fatty acid concentration 0.772522203028611 1.078643463650298 0.2807466978400625 1.0 0.9546582402986696 3 P40855 1 +Abnormal circulating sex hormone concentration 0.4354384798346647 1.0779862634313917 0.2810398863840997 1.0 0.9546582402986696 22 P51809,Q13423,P16870 3 +Abnormal renal tubule morphology 0.436633671221407 1.0777828395183295 0.2811306794701476 1.0 0.9546582402986696 24 P06280,Q15526,Q9Y4P3,P23786,P03886,P03915 6 +Humeroradial synostosis 0.8364470665355614 1.077528045280708 0.2812444284773232 1.0 0.9546582402986696 2 P16435 1 +Elbow ankylosis 0.8364470665355614 1.077528045280708 0.2812444284773232 1.0 0.9546582402986696 2 P16435 1 +Abnormal macular morphology 0.4376830219454886 1.0728485065738926 0.2833390930112016 1.0 0.95625811201804 29 P04062,Q8NHS3,P04439,Q99519,P50897,P51648 6 +Abnormal labia minora morphology 0.5499552301364514 1.0722156254085868 0.283623193726197 1.0 0.95625811201804 8 P16435,Q9Y619,Q15042,O75419 4 +Abnormal lactate dehydrogenase level 0.4317397475874872 1.0684595467929554 0.2853132688005693 1.0 0.95625811201804 19 P38571,P15529,Q9H9S5,O43505,P10253 5 +Diminished motivation 0.4369042090968517 1.0681539207554382 0.2854510864270847 1.0 0.95625811201804 28 P17900,P06865,O00592,Q13501 4 +Abnormal arachnoid mater morphology 0.5491751801785171 1.068128554422676 0.285462527029104 1.0 0.95625811201804 8 Q9UHX1 1 +Hand tremor 0.5098107739097604 1.067743450643695 0.2856362527691791 1.0 0.95625811201804 10 Q16637,P56192 2 +Abnormality of pelvic girdle bone morphology 0.3759121519876573 1.0677032652634224 0.2856543850771427 1.0 0.95625811201804 140 O75844,P55011,P51798,P15260,Q7LGA3,Q96A33,Q9H9S5,Q9NVI7,O95831,Q8TAA9,Q9Y619,O00754,Q8IZA0,Q9BXW9,Q9UHX1,P01889,P16278,Q5SZK8,Q04656,Q96HY6,Q14739,Q9Y487,Q6NUQ1,P08236,P16435,Q8WVQ1,O95202,Q9Y4P3,P36543 29 +Hypohidrosis 0.5288384371776389 1.0645996743238209 0.2870571272736724 1.0 0.9595612522561238 9 P06280 1 +Sensory neuropathy 0.436039607400143 1.0634589371498275 0.28757387740311 1.0 0.9598550998523458 27 Q6DD88,Q8IV08,P00403,O95831,O60313,O15269,P51149,P03886,P03915 9 +Dyspnea 0.3461135836758162 1.0613739824713473 0.2885199759167687 1.0 0.9598550998523458 102 O75844,Q13501,P04114,P07602,P53701,Q15526,P04062,P56192,P06280,Q68CQ7,O95831,Q9Y619,P01130,P03886,Q13510,O75419,P10644,P03915,Q9UHX1,P04350,P01889,P00387,Q02487,P49815,P23786,Q9BZK7,P10253,Q9NZJ7,O95169,P51571,P12235,P35637,Q15165,Q92804 34 +Limited hip movement 0.4958841260628402 1.0606648138428083 0.2888422559727397 1.0 0.9598550998523458 12 Q7LGA3 1 +Soft skin 0.5083604356532059 1.0594971062732028 0.2893734464106088 1.0 0.9598550998523458 10 Q04656,O00754 2 +Truncal ataxia 0.4415890485575655 1.0577829330106847 0.2901544154425426 1.0 0.9598550998523458 18 O75503,P98155 2 +Abnormality of prothrombin 0.4800727096542427 1.0575867558718808 0.2902438831771363 1.0 0.9598550998523458 14 P15529,P38435,Q5XKP0,Q9BV10 4 +Slowly progressive 0.4148983308346226 1.0559823437883464 0.2909762815073151 1.0 0.9598550998523458 54 O14979,P56192,O75787,P12235,O00584,P05023,Q99720,Q04656,Q8IV08,O95831,Q9P0J0,Q16637,O14773,Q15526,P50402 15 +Metaphyseal cupping 0.766327072437486 1.0542106540254077 0.291786483337463 1.0 0.9598550998523458 3 O95831 1 +Recurrent respiratory infections 0.3606383101563746 1.0537299342062243 0.2920065799420812 1.0 0.9598550998523458 121 P09601,P51798,P07602,Q96J02,Q13277,P54802,P04062,P02786,P04066,P53634,P15586,Q13510,P01889,P16278,P00533,P10253,Q9NZJ7,O00462,Q9BV10,Q9Y487,Q03518,P08236,O95202 23 +Rigidity 0.4127534995015186 1.0530658586750976 0.2923108090250328 1.0 0.9598550998523458 55 Q15392,P04062,O75787,P04350,P12235,P16278,Q96CU9,O00592,Q9Y287,P07602,Q9H2C2,Q9H6K4,Q9BPX6,Q9NZJ7 14 +Abnormality of subcutaneous fat tissue 0.4515261395670827 1.0530459785354018 0.2923199198794122 1.0 0.9598550998523458 17 O75844,P17612,Q9Y487,Q6NUK1,P08069,P36543 6 +Abnormal patella morphology 0.4343231627611179 1.052814829224769 0.2924258671261537 1.0 0.9598550998523458 26 P21964,Q9NX62,Q9Y619,Q8WVQ1,Q96PU5 5 +Mortality aging 0.3462937278918718 1.0526815753387433 0.292486955739311 1.0 0.9598550998523458 103 O75844,Q9BT22,P07602,Q13277,Q9H9S5,P05067,P04062,P40855,Q9HC21,P16278,P38571,Q5SZK8,Q04656,Q6NUK1,P07686,Q15904,Q92581,Q9NZJ7,Q14739,Q6NUQ1,P16435,Q9Y4P3 22 +Precocious atherosclerosis 0.765762320366563 1.0519859928952806 0.2928059761217925 1.0 0.9598550998523458 3 P04114 1 +Premature coronary artery atherosclerosis 0.765762320366563 1.0519859928952806 0.2928059761217925 1.0 0.9598550998523458 3 P04114 1 +Aortic atherosclerotic lesion 0.765762320366563 1.0519859928952806 0.2928059761217925 1.0 0.9598550998523458 3 P04114 1 +Premature arteriosclerosis 0.765762320366563 1.0519859928952806 0.2928059761217925 1.0 0.9598550998523458 3 P04114 1 +Abnormal corneal epithelium morphology 0.4292260782521351 1.0496531926169126 0.2938775914309928 1.0 0.9598550998523458 19 O75844,P01889,P39210,Q9NZ08,P51648 5 +Patellar aplasia 0.6671916735757608 1.0480302622184468 0.2946246643945831 1.0 0.9598550998523458 4 Q9Y619 1 +Basal ganglia calcification 0.525799796477661 1.0480205660635458 0.2946291315838789 1.0 0.9598550998523458 9 O00429,P00403,O60313,P03886,P03915 5 +Episodic respiratory distress 0.7645901639344176 1.0473701337261714 0.2949289008758946 1.0 0.9598550998523458 3 P03886,P03915 2 +Chronic rhinitis 0.7640101843142657 1.0450869674293115 0.2959827768632586 1.0 0.9598550998523458 3 Q9BV10 1 +Scarring 0.4343087244373327 1.0448506995140594 0.2960919783973164 1.0 0.9598550998523458 31 P04439,P53634,Q04656,Q92542,Q07954 5 +Cerebral calcification 0.4336817908531857 1.044653090630429 0.2961833326767529 1.0 0.9598550998523458 35 Q16625,O00584,P53634,Q04656,P11166,O60313,P23786,P03886,P05067,P03915 10 +Abnormality of the auditory canal 0.4322627325880011 1.044228618648714 0.296379629182228 1.0 0.9598550998523458 24 Q5SZK8,P00533,P16435,Q9Y619,O95202,Q9H9S5 6 +Abnormal choroid morphology 0.4325608512061968 1.0425409032773572 0.2971609718589705 1.0 0.9598550998523458 25 P04439,Q9Y619,P53701,Q5XKP0,O43505,Q9H9S5 6 +Back pain 0.4326223207079013 1.039605669341248 0.2985231418904293 1.0 0.9598550998523458 26 P01889,P51798,Q5HYI8,P15529,Q8TAA9 5 +Recurrent skin infections 0.4683159173105116 1.0372465219445088 0.2996209818417719 1.0 0.9598550998523458 15 P53634,P02786 2 +Retinal coloboma 0.5430517815887197 1.036039137683137 0.3001838841002737 1.0 0.9598550998523458 8 Q9UHX1 1 +Hyperacusis 0.5623465079187785 1.0348936402182751 0.3007185850503227 1.0 0.9598550998523458 7 P17900 1 +Sound sensitivity 0.5623465079187785 1.0348936402182751 0.3007185850503227 1.0 0.9598550998523458 7 P17900 1 +Akinesia 0.5039973171768394 1.0346803676135936 0.300818207521897 1.0 0.9598550998523458 10 O00592 1 +Abnormal heart valve physiology 0.3474395350822453 1.0343876962700782 0.3009549539882736 1.0 0.9598550998523458 78 P10644,P04062,O75844,Q9UHX1,P01889,P16278,P06280,Q6NUK1,Q15904,P04114,Q9NZ08,P53701,O00754,Q15526,Q9Y4P3,P01130,Q96PU5,P36543 18 +Hyperkeratosis 0.3958633663919115 1.0341070248475333 0.3010861325571958 1.0 0.9598550998523458 62 P04062,O75844,P42167,Q96JJ3,Q06136,Q6DD88,P04066,P53634,P06280,P16615,Q07954,Q14126,Q99519,P51648,O15269,Q14574 16 +Myoclonic seizure 0.4123098691283771 1.0311478151053095 0.3024715080696576 1.0 0.9620863230706656 54 Q96N66,Q99519,P07602,P04062,Q8NHS3,Q9Y619,Q01105,P03886,Q13510,P03915,P16278,Q6PJG6,P07686,Q9NZJ7,O75503,O00429,O43292,P11166,Q5XKP0,Q96CW1,O60508 21 +Progressive visual loss 0.4293909731888956 1.026834007739336 0.3044986328786083 1.0 0.9620863230706656 23 P98164,O75503,O14773,Q99519,P50897,O60313,P03886 7 +Abnormal circulating ceruloplasmin concentration 0.7593442622950767 1.0267376079436283 0.3045440354245816 1.0 0.9620863230706656 3 O00400,Q8N511 2 +Juvenile aseptic necrosis 0.5760732578784475 1.0231801615467322 0.3062226709892308 1.0 0.9620863230706656 6 Q9Y619 1 +Increased total bilirubin 0.6609271302333645 1.0217565113342726 0.3068961570683393 1.0 0.9620863230706656 4 P23786,P14314 2 +Mitral valve calcification 0.6603548879530527 1.0193585395336198 0.3080327818158859 1.0 0.9620863230706656 4 O75844 1 +Cardiac valve calcification 0.6603548879530527 1.0193585395336198 0.3080327818158859 1.0 0.9620863230706656 4 O75844 1 +Abnormal sternum morphology 0.3510766176595206 1.0193184330883092 0.3080518156897138 1.0 0.9620863230706656 112 P55011,Q99519,Q7LGA3,Q96J02,Q96A33,P04062,Q9NVI7,O95831,Q9Y619,O00754,Q9H490,Q13510,Q9UHX1,Q96JJ3,P16278,P55795,Q04656,Q7RTS9,Q92581,P50402,Q14739,Q9Y487,Q15555,P08236,O95202,Q9Y4P3 26 +Abnormal mitochondria in muscle tissue 0.424752737222575 1.016164153600954 0.3095512232800756 1.0 0.9620863230706656 19 O96000,P00403,Q9Y6M9,Q86Y39,O43676,P03886,P03915 7 +Insulin resistant diabetes mellitus 0.5585888641675081 1.0159635813993904 0.3096467293729767 1.0 0.9620863230706656 7 O75844 1 +Stillbirth 0.4945586304999725 1.0140308029969276 0.31056805435834 1.0 0.9620863230706656 11 P04062,O75844,Q14739 3 +Abnormal speech prosody 0.5388332409891127 1.0139289554275557 0.3106166536194479 1.0 0.9620863230706656 8 P04062,P03886 2 +Ectopic kidney 0.4555982353505362 1.0135557491274905 0.3107947817666108 1.0 0.9620863230706656 16 Q8TAA9,Q9Y4P3,Q9UHX1 3 +Adrenocortical abnormality 0.8203867584398721 1.0127966563514013 0.3111572981408739 1.0 0.9620863230706656 2 P10644 1 +Primary hypercortisolism 0.8203867584398721 1.0127966563514013 0.3111572981408739 1.0 0.9620863230706656 2 P10644 1 +Multiple lipomas 0.5576472801330148 1.0112205036881134 0.3119109044537111 1.0 0.9620863230706656 7 Q8TAA9,P03915 2 +Patellar dislocation 0.4247890417587863 1.0094534473870458 0.3127572168737988 1.0 0.9620863230706656 20 Q9NX62,P21964,Q96PU5,Q8WVQ1 4 +Abnormality of limb epiphysis morphology 0.4298196457201593 1.0089032422976243 0.3130210400997819 1.0 0.9620863230706656 31 P10644,Q04656,Q6NUQ1,O95831,P16435,Q8WVQ1,Q7LGA3,O95202 8 +Hyporeflexia of upper limbs 0.8194034742707368 1.008853394970303 0.3130449491198634 1.0 0.9620863230706656 2 O75787 1 +Craniofacial dysostosis 0.6578453009067382 1.0088465161001992 0.313048248629757 1.0 0.9620863230706656 4 P10644 1 +Memory impairment 0.4261931673098567 1.0082917097808763 0.3133144417066436 1.0 0.9622633286236664 41 Q13501,P01889,Q9NZJ7,P00403,Q9NZ08,P07602,Q92673,P03886,P05067,P03915 10 +Fasciculations 0.4284126760100105 1.0071545633495482 0.3138605039462012 1.0 0.96259578489825 37 Q969X5,Q13501,P35637,Q9BTW9,O43819,P06280,Q9Y6X9,O95831,P07686,Q16637,Q9NW15,P07602,P07196,Q13510,Q9NZJ7 15 +Abnormality of the nasal skeleton 0.6142419947316972 1.00504057376236 0.3148773131094453 1.0 0.9632239405725436 5 P10644 1 +Femoral hernia 0.7538140497045145 1.0050348754244574 0.3148800568791232 1.0 0.9632239405725436 3 Q04656 1 +Abnormal subcutaneous fat tissue distribution 0.6135999782417271 1.0021434426514328 0.3162743188167254 1.0 0.9653268006059468 5 P36543,Q9Y487 2 +Diastema 0.5717212882748333 1.0019752526869374 0.3163555452933542 1.0 0.9653268006059468 6 Q9BSJ2,Q8WVM7,P17612,Q8TC12 4 +Laryngeal stenosis 0.656080269206105 1.001457672553947 0.3166055938363912 1.0 0.9653268006059468 4 Q5SZK8 1 +Areflexia 0.3581511643894499 0.994844740374864 0.3198117824313473 1.0 0.968549452864389 74 Q13501,P39210,P05023,Q9BT22,Q15526,Q9H6K4,Q9H9S5,P56192,O95831,Q16637,Q9Y6B6,Q13510,O75787,O43505,P10253,P12235,O60313,O15269,P07196,P51149 20 +Chorioretinal hypopigmentation 0.7511475409835886 0.994589330741976 0.3199360387249792 1.0 0.968549452864389 3 Q9Y619,P49815 2 +Decreased ldl cholesterol concentration 0.611668437256715 0.9934295281340229 0.3205006776058163 1.0 0.968549452864389 5 Q9Y6B6,P04114 2 +Abnormality of the tarsal bones 0.4265652373555025 0.992529324212289 0.3209393820304231 1.0 0.968549452864389 26 O75844,Q14739,O75787,Q9UHX1,Q04656,P16435,Q8WVQ1 7 +Anencephaly 0.4426498135482573 0.9912194652997812 0.3215784277169482 1.0 0.968549452864389 17 Q8TAA9,O43505 2 +Peripheral arterial stenosis 0.6535733099654812 0.990969576856238 0.321700436015691 1.0 0.968549452864389 4 P04114 1 +Metatarsus adductus 0.4693938681425936 0.9899721601356448 0.3221877267976223 1.0 0.968549452864389 14 Q15392,Q96L58,P08236,P50542,Q9UBM7,O95202,Q08J23 7 +Papule 0.4221809236827708 0.9898190722007282 0.3222625609584431 1.0 0.968549452864389 20 O75844,P01889,P16615,P38435,Q07954,Q9NZ08 6 +Deformed sella turcica 0.6108555912772785 0.9897635265237577 0.3222897162228924 1.0 0.968549452864389 5 P08236,Q96AX1,Q7RTS9 3 +Rhinitis 0.5692141332750087 0.9897631056388628 0.3222899219915103 1.0 0.968549452864389 6 Q9BV10 1 +Proximal amyotrophy 0.4691160983439845 0.98821258187684 0.3230485474825468 1.0 0.968593798276299 14 O14979,P35637,Q16637,Q9H9S5,P07196,P50402 6 +Heterogeneous 0.4180652792095224 0.9879336034113676 0.32318516689152 1.0 0.968593798276299 47 O75844,P61916,P12235,P21964,P53634,Q15555,P51798,P11717,Q14126,Q9Y619,P03886,P05067,Q9BQE5 13 +Scaphocephaly 0.652567708996779 0.9867648314451444 0.3237579392069065 1.0 0.968593798276299 4 P40855 1 +Conspicuously happy disposition 0.7490084324068799 0.9862191342408464 0.3240255917563135 1.0 0.968593798276299 3 Q92581 1 +Poor head control 0.3727558136679254 0.9846695231129792 0.3247864276395014 1.0 0.9689883472998858 69 P06865,Q5KU26,O96000,Q9Y6M9,Q9P0J0,Q86Y39,P07602,O43676,Q9H2C2,P17900,Q9NWM8,Q5XKP0,P03886,P13073,Q9NZJ7 15 +Short palm 0.4229424881304497 0.983008176066118 0.3256034146771833 1.0 0.9693557772586732 22 P10644,Q04656,Q9Y619,Q9UHX1 4 +Infectious encephalitis 0.532927876805482 0.9829798237486344 0.3256173688531749 1.0 0.9693557772586732 8 Q9NZ08,P01889 2 +Jaundice 0.4105849105353027 0.9827910949955728 0.3257102654998793 1.0 0.9693557772586732 52 P10644,Q14739,O15118,P61916,Q16625,P40855,P39210,O75787,P38571,Q04656,Q5HYI8,Q15904,P11166 13 +Deep palmar crease 0.4826046149086281 0.9811651746826764 0.3265112946956996 1.0 0.9695331032243812 12 Q9Y487,Q6NUK1,P42345,Q96AX1,Q9BZK7 5 +Adrenal overactivity 0.6509272162821145 0.97990830893891 0.327131381137026 1.0 0.9695331032243812 4 P10644 1 +Abnormality of circulating leptin level 0.6506830829333774 0.978888256586722 0.3276351952507601 1.0 0.9695331032243812 4 O75844 1 +Microtia third degree 0.8118649623074581 0.9787059308015428 0.3277253008121481 1.0 0.9695331032243812 2 Q9Y619 1 +Congenital sensorineural hearing impairment 0.6083012506317109 0.9782475618305856 0.32795189818362 1.0 0.9695331032243812 5 Q16740 1 +Abnormality on pulmonary function testing 0.4222887131947541 0.9780342243305562 0.3280573974778149 1.0 0.9695331032243812 22 P01889,P16278,Q9Y285,Q96J02,Q9H9S5 5 +Restrictive ventilatory defect 0.4748379719798558 0.9762865975559608 0.3289224596891733 1.0 0.9695331032243812 13 P16278,Q9Y285,P01889,Q9H9S5 4 +Kyphosis 0.3681731849056003 0.97302983975721 0.330538471815325 1.0 0.9718280018872596 139 Q9HC07,O75844,P55011,Q9BT22,Q99519,Q15526,Q7LGA3,P07237,Q9H9S5,P04062,P04066,O95831,O00754,Q86UE8,P10644,Q9UHX1,P01889,Q15042,P16278,Q04656,Q7RTS9,Q14108,Q9NWM8,P50402,Q14739,Q9Y487,P08236,P48651,P51648,Q8WVQ1,Q5KU26,O95202,Q9Y4P3,P36543 34 +Laryngeal dystonia 0.8098983939691891 0.9708669104283248 0.3316145577121938 1.0 0.9720993783109392 2 O75569 1 +Abnormal circulating gonadotropin concentration 0.4580589819421563 0.9702931419942789 0.3319003947192129 1.0 0.9720993783109392 15 P51809,P16870 2 +Absence of secondary sex characteristics 0.6481928734443826 0.968488335070854 0.3328005419454118 1.0 0.9726661575712264 4 P51809 1 +Sunken cheeks 0.7439481903970007 0.9664535417162184 0.3338172834355508 1.0 0.9740032438255508 3 Q07954 1 +Abnormality of the lymphatic system 0.3723702445355316 0.961687900543953 0.3362064019838469 1.0 0.9742189419579792 146 P61916,Q16625,P10619,P51798,Q99519,P07602,P15260,Q96J02,Q96A33,P54802,P04062,O15118,P04066,Q5HYI8,Q9NZ08,O00754,P15586,Q13510,P10644,P01889,P16278,P38571,P07686,Q15904,Q14108,P10253,Q96HY6,Q9NZJ7,Q14739,P21964,P08236,P11166,O95202,P31751 34 +Brushfield spots 0.7426229508196693 0.9612855056242277 0.3364086337305103 1.0 0.9742189419579792 3 O75381,P40855 2 +Neoplasm of the male external genitalia 0.4854568225240906 0.9609217925108716 0.3365914924703963 1.0 0.9742189419579792 11 P10644,P51809,Q13423 3 +Respiratory failure 0.3863778817220944 0.9597561230603634 0.3371779698052655 1.0 0.9742189419579792 63 P61916,Q13501,Q70HW3,Q9BT22,P07602,P53701,Q15526,Q9H9S5,Q68CQ7,Q16637,Q9Y619,Q13510,P23786,P10253,O95169,Q9NZJ7,P35637,Q15165,Q5XKP0 19 +Flared iliac wing 0.6041655529652036 0.959617290593474 0.3372478636293454 1.0 0.9742189419579792 5 P16278 1 +Paresthesia 0.4189451116781029 0.9587620884136072 0.3376786120131525 1.0 0.9742189419579792 21 P54802,P06280,Q9NZ08,P11166,P05067 5 +Brittle hair 0.4562309680030862 0.9583563896351706 0.337883078012366 1.0 0.9742189419579792 15 O75844,Q6NUK1,Q9Y487 3 +Microglossia 0.6457018509658745 0.9580941338443622 0.3380152932455749 1.0 0.9742189419579792 4 P48651,P08754 2 +Premature loss of teeth 0.4641571047314932 0.9567961088148604 0.338670176669815 1.0 0.9742189419579792 14 O75844,P53634 2 +Aplasia hypoplasia of the sacrum 0.7407087162934605 0.9538269855683528 0.3401712272431787 1.0 0.9742189419579792 3 P04066 1 +Neoplasm of the heart 0.8046542117338761 0.9500175298237972 0.3421033454701432 1.0 0.9742189419579792 2 P10644 1 +Abnormality of the subungual region 0.8046542117338755 0.9500175298237956 0.3421033454701438 1.0 0.9742189419579792 2 P16615 1 +Shagreen patch 0.804654211733866 0.9500175298237572 0.3421033454701634 1.0 0.9742189419579792 2 Q6NUK1 1 +Focal cortical dysplasia type ii 0.8046542117338562 0.950017529823718 0.3421033454701834 1.0 0.9742189419579792 2 P42345 1 +Hemimegalencephaly 0.8046542117338562 0.950017529823718 0.3421033454701834 1.0 0.9742189419579792 2 P42345 1 +Unusual infection by anatomical site 0.4771954982995446 0.9487669038646896 0.3427391780709801 1.0 0.9742189419579792 12 Q8TAA9,Q9NZ08,P02786,P01889 4 +Abnormal circulating non proteinogenic amino acid concentration 0.5261449353976516 0.9474443877433284 0.3434123816884917 1.0 0.9742189419579792 8 Q9Y619,P05067,P03886 3 +Oculomotor apraxia 0.4206575049287496 0.9465753350462665 0.3438552172772926 1.0 0.9742189419579792 26 Q13501,P05067,Q92673 3 +Narrow mouth 0.3573611572941045 0.946420970722887 0.3439339134730121 1.0 0.9742189419579792 73 Q15392,O75844,P55011,Q7LGA3,Q9NVI7,P04062,P08069,Q9Y619,Q86UE8,Q15042,Q5SZK8,Q6NUK1,P21964,Q96C86,Q9Y487,Q15555,Q9NX62,P16435,Q8WVQ1 19 +Abnormality of thyroid physiology 0.3506478663251027 0.943504946355056 0.3454226864623821 1.0 0.9742189419579792 75 O95470,Q96J02,O14654,P56192,P04066,Q07021,O95155,Q8WWQ0,P03886,P03915,P10644,Q13423,P54198,P16870,P00403,P49815,Q16531,P12235,P21964,Q9Y285,O00429,O76024,O60313,Q9Y4P3 24 +Hypermetric saccades 0.7380327868852183 0.9434137072594416 0.3454693346642721 1.0 0.9742189419579792 3 O14773,Q9NW15 2 +Impaired proprioception 0.4216397272339465 0.9433247838075433 0.3455148028010126 1.0 0.9742189419579792 31 P54802,P07196,Q8IV08,O14773,Q9Y619,Q9Y6B6,O00400 7 +Abnormal bone structure 0.3893308960702303 0.942729617986043 0.3458192198257386 1.0 0.9742189419579792 173 Q9HC07,O75844,Q13501,P51798,Q99519,P07602,Q15043,Q13277,P07237,P54802,P04062,P40855,Q6DD88,P53634,Q9UG56,P06280,Q9HC21,O95831,Q9Y619,O00754,Q9H490,Q13510,P10644,Q9BXW9,Q96JJ3,Q15042,P16278,Q04656,Q6NUK1,Q7RTS9,Q14108,Q9NWM8,Q96HY6,Q9NZJ7,P51809,Q14739,P12235,Q9BV10,Q9Y487,P38435,O43292,P08236,Q86XL3,P48651,Q8WVQ1,O95202,Q9Y4P3 47 +Profound global developmental delay 0.4692367254727198 0.9418064418890456 0.346291746466167 1.0 0.9742189419579792 13 Q9H490,P40855,O60313,Q92581 4 +Tetraplegia 0.4759841753497774 0.9415118321653604 0.3464426286347462 1.0 0.9742189419579792 12 O95831,P51572,Q13423 3 +Hallux valgus 0.4348656201393021 0.9369636100687134 0.3487772768115396 1.0 0.9742189419579792 17 P04062,Q9Y4P3,Q96J02 3 +Ureteral duplication 0.5425546837948482 0.9352454610019506 0.3496618149645707 1.0 0.9742189419579792 7 O75844,Q8TAA9 2 +Increased susceptibility to fractures 0.4054785244216875 0.9345603717557212 0.3500149095716001 1.0 0.9742189419579792 52 P10644,P04062,Q14739,Q13501,P39210,Q04656,P51798,P16435,Q14108,O15269,P07237 11 +Heart block 0.4161611362135731 0.9314047794509472 0.3516442194929796 1.0 0.9742189419579792 22 P19022,P23786,P06280,Q07954,P0DP25,Q9H490,P36543 7 +Movement abnormality of the tongue 0.6391716156238543 0.9308925156941142 0.3519091663818183 1.0 0.9742189419579792 4 P04350,P10253 2 +Abnormal social behavior 0.3810216883006693 0.9285664776714329 0.3531138013005832 1.0 0.9742189419579792 64 O96008,Q9Y6M9,Q96CU9,Q9P0J0,O00592,P07602,Q2TAA5,P05067,Q92673,P03886,Q9UHX1,O96000,Q10471,Q86Y39,O43676,Q9NZJ7,P11166,Q5KU26,Q5XKP0,Q9Y4P3 20 +Mandibular prognathia 0.4173823883700864 0.9270599106052904 0.3538954292411624 1.0 0.9742189419579792 40 P10644,Q9NVI7,Q9UHX1,P55011,P16278,Q6NUK1,Q7RTS9,O00754,Q92581 9 +Abnormal oral mucosa morphology 0.3831605362647191 0.9257029674995542 0.3546003652870315 1.0 0.9742189419579792 63 P10644,P04062,Q14739,P01889,Q96JJ3,P16278,P53634,P08236,Q9NZ08,Q99519,Q14108,O00754 12 +Epiphora 0.5966214023336156 0.9256881261165752 0.3546080803291933 1.0 0.9742189419579792 5 Q07954 1 +Supernumerary spleens 0.5219116545962106 0.9252792883241384 0.3548206494228338 1.0 0.9742189419579792 8 Q15904 1 +Abnormal peripheral myelination 0.4189396349189863 0.9245327349459902 0.3552090162010537 1.0 0.9742189419579792 29 Q9NZJ7,P39210,P07602,O15269,Q15526,P07196,P03886,P03915 8 +Azoospermia 0.4729358528668942 0.9232559100834622 0.3558738585723136 1.0 0.9742189419579792 12 P04062,P51809,Q9BXW9,Q13423,Q92889 5 +Urinary incontinence 0.4129985580318303 0.9231163541585984 0.3559465728491913 1.0 0.9742189419579792 45 Q13501,P35637,Q99720,Q3ZCQ8,Q10471,P07686,Q8TAA9,P11166,P07602,Q92581,Q9NZJ7 11 +Morning glory anomaly 0.7964601769911557 0.9176090845160562 0.358823560117415 1.0 0.9742189419579792 2 O60313 1 +Temporal optic disc pallor 0.7964601769911557 0.9176090845160562 0.358823560117415 1.0 0.9742189419579792 2 O60313 1 +Autoimmune antibody positivity 0.4779884577740415 0.9173450719273096 0.3589618460254113 1.0 0.9742189419579792 11 P15260 1 +Wormian bones 0.4114421140669437 0.9164283411892468 0.3594422761622604 1.0 0.9742189419579792 19 O95831,O75844,Q04656,Q9Y487 4 +Difficulty in tongue movements 0.7961324156014657 0.9163172469473508 0.3595005246403917 1.0 0.9742189419579792 2 P10253 1 +Dermatological manifestations of systemic disorders 0.3772652071839429 0.9147972669180732 0.3602980698813656 1.0 0.9742189419579792 65 P10644,O75844,Q14739,P61916,Q16625,P40855,O15118,P39210,O75787,P38571,P04066,Q04656,Q5HYI8,Q15904,P11166 15 +Anarthria 0.5384180876012126 0.9144499625818748 0.3604804589077257 1.0 0.9742189419579792 7 Q99720,O00592 2 +Cardiomegaly 0.4180206328675778 0.913715675625456 0.3608662649818521 1.0 0.9742189419579792 32 P54802,P04062,P10644,Q14739,P04066,P07686,Q99519,P23786,Q9Y4P3,P10253 10 +Multifactorial inheritance 0.4709291538266555 0.9112400496607292 0.3621689062640607 1.0 0.9742189419579792 12 P42892,P10321 2 +Pathologic fracture 0.4488528096015918 0.91018054153913 0.3627273043151655 1.0 0.9742189419579792 15 P04062,Q14108,O15269 3 +Impaired tactile sensation 0.5177549608164558 0.9035289074176476 0.3662452532517108 1.0 0.9742189419579792 8 P39210,Q6DD88,O15269 3 +Abnormality of thalamus morphology 0.4200450175129174 0.9022838645953588 0.3669060946494773 1.0 0.9742189419579792 18 Q9UPT5,O43819,Q9Y5P6,P11166,Q15526,O75306,Q9H9S5,O95169 8 +Hypoglycemic seizures 0.5353509158832235 0.899041976967277 0.3686303020684915 1.0 0.9742189419579792 7 Q13423 1 +Generalized myoclonic atonic seizure 0.7915437561455441 0.8982696145394647 0.369041827750503 1.0 0.9742189419579792 2 P11166 1 +Eeg with focal spike waves 0.7915437561455441 0.8982696145394647 0.369041827750503 1.0 0.9742189419579792 2 P11166 1 +Lumbar hyperlordosis 0.409963747643655 0.8978077689613239 0.3692880420981534 1.0 0.9742189419579792 20 Q96J02,P04066,Q96HY6,Q9H9S5 4 +Abnormal blood potassium concentration 0.4746055490464123 0.8976136435197152 0.369391562731344 1.0 0.9742189419579792 11 P11166,Q13423,P0DP25 3 +Emg abnormality 0.353226026374785 0.8968071342858884 0.3698218404027982 1.0 0.9742189419579792 73 P50402,P42167,Q13501,P12235,Q9NZJ7,P39210,Q6DD88,Q04656,Q14126,Q16637,O14773,P07602,O60313,O15269,Q9Y6B6,Q9H9S5,Q13510,P03915 18 +Acute hepatic failure 0.4618515294854879 0.8963557226773519 0.3700628071866219 1.0 0.9742189419579792 13 P39210,P38571,P01889,Q96J02 4 +Elevated pulmonary artery pressure 0.41418696494067 0.8962251006328336 0.3701325523721037 1.0 0.9742189419579792 26 P04062,O75844,P01889,P51798,Q6NUK1,O96000,Q14108,Q8IZA0,P03886,P03915 10 +Megalencephaly 0.7251694959916782 0.8935868886719044 0.3715429640333914 1.0 0.9742189419579792 3 P42345 1 +Omphalocele 0.4611820978005438 0.8922372926363484 0.3722657572869283 1.0 0.9742189419579792 13 Q5SZK8,P98164 2 +Abnormal visual electrophysiology 0.4095114962686764 0.8921104880052951 0.3723337138746723 1.0 0.9742189419579792 45 P12235,Q15042,O75503,Q15555,P51798,O14773,P07602,P50897,Q9NZJ7 9 +Truncal titubation 0.7899049491969825 0.8918416678491995 0.3724778042308503 1.0 0.9742189419579792 2 Q6PJG6 1 +Megalocornea 0.467473512221441 0.8905534593806991 0.3731687765973843 1.0 0.9742189419579792 12 O95202,Q9H9S5 2 +Ecchymosis 0.467279548672883 0.8893925761995123 0.3737921333596421 1.0 0.9742189419579792 12 P10644,P38435 2 +Intellectual disability progressive 0.473174508005406 0.8892690712818765 0.3738584894112773 1.0 0.9742189419579792 11 Q15067,O95831,Q92889,P53701,Q92581 5 +Photophobia 0.4144358654883184 0.8879791719165372 0.3745519550569853 1.0 0.9742189419579792 36 P01889,P04439,Q15555,Q9NZ08,Q9Y287,P07602,P51648 7 +Abnormal meningeal morphology 0.4125392287614038 0.8877084453364704 0.3746976018863606 1.0 0.9742189419579792 25 Q9UHX1,Q5SZK8,Q15904,Q8TAA9,Q9H9S5 5 +Abnormality of the gingiva 0.4032519031902877 0.8869359839242286 0.3751133669465287 1.0 0.9742189419579792 50 P10644,P04062,Q14739,Q96JJ3,P16278,P53634,P08236,Q99519,Q14108,O00754 10 +Postural instability 0.427268900387632 0.8840212581506147 0.3766847373670072 1.0 0.9742189419579792 17 O75503,O00592 2 +Aplasia hypoplasia of the tibia 0.6277770057701613 0.8836139913784655 0.37690462359772 1.0 0.9742189419579792 4 Q04656 1 +Visual loss 0.4014729983943919 0.8830650657876215 0.3772011176563052 1.0 0.9742189419579792 51 P98164,P01889,Q96JJ3,Q9NZJ7,Q8NHS3,O75503,P04439,P51798,O14773,Q99519,P53701,P07602,P50897,O60313,P03886,P03915 16 +Lymphedema 0.4361434183987464 0.8824350832756815 0.3775415705790497 1.0 0.9742189419579792 16 P08236,P06280 2 +Disproportionate tall stature 0.4121024281173347 0.8800050758603506 0.3788565598241757 1.0 0.9742189419579792 26 P55011,P16435,O00754,Q7LGA3,O95202,P36543 6 +Entropion 0.4715365017091937 0.8797196362153481 0.3790112091855309 1.0 0.9742189419579792 11 Q92889,O75844,P01889,P36543 4 +Abnormality of globe size 0.3831726534846113 0.8783445901732311 0.3797567444201442 1.0 0.9742189419579792 61 O75569,Q92889,P53701,Q9NP72,Q9H9S5,Q9P273,Q9Y5P6,P18074,Q9BXW9,Q9UHX1,P54198,Q15042,Q5SZK8,Q6NUK1,O43505,Q9BZK7,P21964,Q15555,P11166,Q96CW1 20 +Genu valgum 0.4134403909003978 0.8765235960254857 0.3807454545432538 1.0 0.9742189419579792 33 P16278,Q04656,Q9NX62,P08236,Q9Y619,O00754,Q7LGA3 7 +Anterior uveitis 0.72065573770491 0.876201070493372 0.3809207346806613 1.0 0.9742189419579792 3 P14174,P01889 2 +Poor motor coordination 0.4649825370458559 0.8756472008300458 0.381221856980197 1.0 0.9742189419579792 12 O75503 1 +Glucose intolerance 0.3301750196146084 0.8756156043650081 0.3812390394337213 1.0 0.9742189419579792 99 O75844,Q9Y6M9,Q96J02,Q5HYI8,Q8TAA9,P03886,P03915,P10644,P16870,Q96JJ3,Q06136,O96000,Q86Y39,O43676,P12235,Q15555,O76024,O60313,Q9Y4P3,P31751 20 +Malabsorption 0.3990219772787857 0.8734871010640465 0.3823976339259123 1.0 0.9742189419579792 52 Q14739,P40855,P01889,P09601,P38571,Q04656,P06280,O76024,Q9NZ08,Q9Y6B6,Q96A33 11 +Aplasia hypoplasia of the hallux 0.4257092200659741 0.8731562502245812 0.3825779174795598 1.0 0.9742189419579792 17 Q7LGA3,O95202,Q9UHX1 3 +Abnormal diaphysis morphology 0.3733508358989612 0.8723233145933459 0.3830320221133181 1.0 0.9742189419579792 65 Q9HC07,P51798,Q7LGA3,P07237,P17612,Q9Y619,O00754,P16278,Q04656,Q7RTS9,Q96HY6,Q14739,Q9Y487,Q9NX62,P08236,P16435,P48651,Q8WVQ1,Q9Y4P3 19 +Abnormality of bone mineral density 0.3570728218114989 0.8719702242676294 0.3832246215465842 1.0 0.9742189419579792 134 Q9HC07,O75844,Q13501,P51798,P07602,Q15043,Q13277,P07237,P54802,P04062,Q9HC21,P06280,O95831,O00754,Q9H490,Q13510,P10644,Q9BXW9,Q15042,P16278,Q04656,Q14108,Q9NWM8,Q96HY6,Q9NZJ7,P51809,Q14739,P12235,Q9Y487,O43292,P48651,Q8WVQ1,O95202,Q9Y4P3 34 +Recurrent sinopulmonary infections 0.5449275584110512 0.8717439232522269 0.3833480926697139 1.0 0.9742189419579792 6 P02786 1 +Cranial hyperostosis 0.4345560711028435 0.8717425636215325 0.3833488345655864 1.0 0.9742189419579792 16 P10644,Q92889,P48651,O00754,Q15043 5 +Dyskinesia 0.3598180007044561 0.8693637173395111 0.3846482218319134 1.0 0.9742189419579792 70 O75569,Q96N66,P55011,Q9Y4P8,Q9P0J0,O00592,Q15526,Q15043,P04062,Q01105,Q9BPX6,P03886,P03915,Q9H2C2,O95169,Q96C86,Q9UBX3,P11166,Q9NZ01 19 +Abnormal arterial physiology 0.4106971048409828 0.8690712603625613 0.3848081551063571 1.0 0.9742189419579792 26 O75844,Q14739,P01889,P06280,Q9NZ08,Q9Y4P3,P05067 7 +Congenital onset 0.3313286990172889 0.8690616601125882 0.3848134057965233 1.0 0.9742189419579792 101 Q8TCJ2,Q96N66,P55011,P07602,Q7LGA3,P08670,Q9H9S5,O95630,Q96PU5,P17612,Q9BTW9,P98155,Q9HC21,Q9Y5P6,P08069,P46977,Q969X5,Q9UHX1,Q15042,O14678,Q6NUK1,P36404,O43505,Q9NZJ7,Q96EK5,P51571,P12235,Q96C86,O43819,Q8NFH4,P78318,Q5KU26,Q5XKP0,P11233,Q4J6C6,O60508 36 +Abnormal size of the clitoris 0.425060308397761 0.868636508232132 0.3850459791678493 1.0 0.9742189419579792 17 P51809,O75381,P40855,P16435,Q9UBM7,P53701,Q9Y619,Q9UNW1,O75419 9 +Small earlobe 0.5110394456503865 0.8684270891885709 0.3851605704972782 1.0 0.9742189419579792 8 P21964 1 +Migraine 0.4085219070224956 0.8672024019433039 0.3858311204468887 1.0 0.9742189419579792 23 P12235,P01889,P00403,Q9NZ08,P11166,O60313,P03886,P05067,P03915 9 +3 methylglutaconic aciduria 0.4744858319992766 0.8667501135696515 0.3860789409486007 1.0 0.9742189419579792 10 Q9NVI7,Q3ZCQ8,Q5XKP0,Q9H6K4 4 +Abnormality of pulmonary circulation 0.4120365837828875 0.8662785997045731 0.3863373990475773 1.0 0.9742189419579792 31 P04062,O75844,P01889,P51798,Q6NUK1,O96000,Q9NZ08,Q14108,Q8IZA0,P03886,P03915 11 +Mitral stenosis 0.7177823325184824 0.865162454576973 0.3869496295171757 1.0 0.9742189419579792 3 O75844 1 +Aortic valve calcification 0.7177823325184824 0.865162454576973 0.3869496295171757 1.0 0.9742189419579792 3 O75844 1 +Excessive wrinkling of palmar skin 0.7175147216510971 0.8641355714408406 0.3875134202211456 1.0 0.9742189419579792 3 Q9Y487 1 +Thin ribs 0.4628290923181847 0.8627654324415348 0.3882664484501565 1.0 0.9742189419579792 12 O75844,Q9Y619 2 +Abnormal thyroid hormone level 0.716908933731617 0.8618117833736417 0.3887910996006007 1.0 0.9742189419579792 3 P16870 1 +Titubation 0.4913342200453962 0.8600035975878677 0.3897870593849604 1.0 0.9742189419579792 9 Q99720,P35637,Q6PJG6 3 +Abnormal metacarpal morphology 0.4112425625080566 0.8599083559800703 0.3898395620226091 1.0 0.9742189419579792 31 P10644,Q9BXW9,Q14739,P16278,Q9NX62,P08236,P16435,Q8WVQ1 8 +Bradykinesia 0.4082648467797497 0.8596769934223059 0.3899671202466228 1.0 0.9742189419579792 24 P04062,O75787,P12235,O00592,Q15043,Q6DKK2 6 +Vitiligo 0.5091708467630242 0.8586700821189236 0.3905225609512706 1.0 0.9742189419579792 8 P03886,P03915 2 +Abnormal pulmonary valve morphology 0.4485823600164479 0.8581669803373934 0.3908002661058432 1.0 0.9742189419579792 14 P10644,P21964 2 +Aplasia hypoplasia of the nipples 0.4406983639799245 0.8569699286065522 0.3914615040335349 1.0 0.9742189419579792 15 O95202,Q96A33,P10586 3 +Abnormality of the axillary hair 0.5266148927190031 0.855222129802405 0.3924281872587927 1.0 0.9742189419579792 7 Q02487,P51809,Q14574 3 +Proximal tubulopathy 0.4060783113495931 0.8546850650309286 0.3927255207936739 1.0 0.9742189419579792 22 P98164,O96000,Q9Y6M9,P00403,Q86Y39,O43676,P03886,P03915 8 +Bicornuate uterus 0.4722942057527683 0.8542961572242618 0.3929409158596386 1.0 0.9742189419579792 10 Q92889,Q5SZK8,Q9BXW9,P98164 4 +Macrogyria 0.5803043823335297 0.85261667669684 0.393871911414166 1.0 0.9742189419579792 5 O43505,Q9H9S5 2 +Blue irides 0.5078601409568012 0.8518291500037373 0.39430892485837 1.0 0.9742189419579792 8 P10644 1 +Tracheal stenosis 0.6197661911182419 0.8505404327445931 0.3950246909913155 1.0 0.9742189419579792 4 Q5SZK8 1 +Cranial asymmetry 0.5405011846659556 0.8503166268245207 0.3951490749910684 1.0 0.9742189419579792 6 O95202 1 +Abnormal waist to hip ratio 0.5399213455059261 0.8475122598414672 0.3967096565231673 1.0 0.9742189419579792 6 Q9Y6M1,O76024,P18031,P31751 4 +Widely spaced incisors 0.7127868852458972 0.8460281284327091 0.3975370527640498 1.0 0.9742189419579792 3 Q9BSJ2,Q8WVM7 2 +Clonus 0.4095490288074148 0.8453029303218267 0.3979417253948552 1.0 0.9742189419579792 32 Q9NVC6,O75787,P35637,Q99720,Q3ZCQ8,Q6PJG6,Q9Y619,P07602,Q15043,Q9NP72,O00400,Q9H9S5,Q9NZJ7 13 +Concentric hypertrophic cardiomyopathy 0.618440675665329 0.8450826099761949 0.3980647169678972 1.0 0.9742189419579792 4 P03886,P03915 2 +Abnormality of the tonsils 0.5244146221755618 0.844203706903965 0.3985555834826011 1.0 0.9742189419579792 7 P21964 1 +Insidious onset 0.7122944072800763 0.8441457741278073 0.3985879516825457 1.0 0.9742189419579792 3 P04062 1 +Contractures of the large joints 0.7121311475409811 0.8435219234620027 0.3989366098162756 1.0 0.9742189419579792 3 O75431,P50542 2 +Bruising susceptibility 0.4089558544709236 0.841564725360972 0.400031641047446 1.0 0.9742189419579792 31 P10644,P04062,Q9BXW9,P17612,Q04656,P51798,P38435,Q86YV9,Q14108,Q9NWM8,Q9BZK7 11 +Talipes equinovarus 0.3544705105965917 0.8404926354799006 0.4006322290593158 1.0 0.9742189419579792 71 P21964,Q9Y487,Q9BV10,O95202,Q9HC21,Q7RTS9,Q6NUQ1,P08236,Q8TAA9,Q9Y619,P16435,O00754,Q8WVQ1,Q9NWM8,Q96A33,P36543 16 +Abnormality of metacarpal epiphyses 0.5770955992432891 0.8383087899812891 0.4018573004536325 1.0 0.9742189419579792 5 O95202 1 +Spondyloepimetaphyseal dysplasia 0.5230563955353751 0.8374061889130481 0.4023642881429321 1.0 0.9742189419579792 7 O95831,Q96HY6 2 +Inverted nipples 0.5225130173151808 0.8346876690741882 0.4038935862494281 1.0 0.9742189419579792 7 Q2TAA5,Q9BV10 2 +Calf muscle pseudohypertrophy 0.7751556866601352 0.8344393938375627 0.4040334261860132 1.0 0.9742189419579792 2 Q9H9S5 1 +Decreased cervical spine mobility 0.7751556866601352 0.8344393938375627 0.4040334261860132 1.0 0.9742189419579792 2 Q9H9S5 1 +Abnormality of the tongue muscle 0.7751556866601352 0.8344393938375627 0.4040334261860132 1.0 0.9742189419579792 2 Q9H9S5 1 +Fusion of the cerebellar hemispheres 0.7751556866601352 0.8344393938375627 0.4040334261860132 1.0 0.9742189419579792 2 Q9H9S5 1 +Abnormal muscle fiber alpha dystroglycan 0.7751556866601352 0.8344393938375627 0.4040334261860132 1.0 0.9742189419579792 2 Q9H9S5 1 +Adducted thumb 0.4055553140403281 0.8336963157411231 0.4044521347790544 1.0 0.9742189419579792 25 Q86XL3,Q04656,P42892,Q92581 4 +Abnormal brainstem mri signal intensity 0.4199086322546112 0.8327727682474828 0.4049728956532363 1.0 0.9742189419579792 17 O96000,Q9Y6M9,O95831,Q86Y39,O43676,P03886 6 +Meningitis 0.5219968705413515 0.832105889898515 0.4053491775798679 1.0 0.9742189419579792 7 Q9NZ08,Q8TAA9,P02786 3 +Aplasia hypoplasia of the cerebral white matter 0.485937856851415 0.8306466590570385 0.4061732678870928 1.0 0.9742189419579792 9 P03915,P11166,P03886,P00403 4 +Dyspareunia 0.7741724024910035 0.8306430519343392 0.4061753062227646 1.0 0.9742189419579792 2 P01889 1 +Bimanual synkinesia 0.7741724024909927 0.8306430519342963 0.4061753062227888 1.0 0.9742189419579792 2 P19022 1 +Eunuchoid habitus 0.7741724024909842 0.8306430519342638 0.4061753062228073 1.0 0.9742189419579792 2 P04350 1 +Thick hair 0.5212304412146219 0.8282731094262701 0.4075158480986234 1.0 0.9742189419579792 7 Q9BUK6,Q04656,P36543,Q9Y487 4 +Disinhibition 0.3842237439516993 0.8271553037301838 0.4081490416030964 1.0 0.9742189419579792 58 P04062,Q96N66,Q13501,P55011,P19022,P35637,Q96C86,O00592,Q8TAA9,Q92673,Q9H2C2,Q9NZ01,P05067 13 +Pericardial effusion 0.5739027562611911 0.8240954898350777 0.4098853026382125 1.0 0.9742189419579792 5 P04062,Q14108 2 +Abnormal hypothalamus morphology 0.7068852459016381 0.823520234773428 0.410212215112993 1.0 0.9742189419579792 3 O43924,P19022 2 +Absent septum pellucidum 0.4068162851147323 0.8232414695511336 0.4103706907010471 1.0 0.9742189419579792 32 Q96N66,P55011,Q96C86,O95202,P48651,P53701,Q9NZ01,O43505,Q9H9S5 9 +Joint hemorrhage 0.7722058341527576 0.8230624734939438 0.4104724675683455 1.0 0.9742189419579792 2 P38435 1 +Vitreous hemorrhage 0.6124946424946438 0.8206554935686278 0.4118425286078693 1.0 0.9742189419579792 4 O15484,Q99496 2 +Abnormal circulating apolipoprotein concentration 0.7061080819862762 0.8205644844867158 0.4118943844484934 1.0 0.9742189419579792 3 Q9Y487 1 +Abnormal cutaneous elastic fiber morphology 0.7061080819862762 0.8205644844867158 0.4118943844484934 1.0 0.9742189419579792 3 Q9Y487 1 +Prominent veins on trunk 0.7061080819862762 0.8205644844867158 0.4118943844484934 1.0 0.9742189419579792 3 Q9Y487 1 +Generalized joint laxity 0.4612552415959079 0.8198473999165548 0.4123031057585122 1.0 0.9742189419579792 11 Q9UHX1,Q9Y487 2 +Abnormal gallbladder morphology 0.4053029574275922 0.8194951497858947 0.4125039680724316 1.0 0.9742189419579792 28 P04062,P40855,P21964,P07602,Q96A33,Q9NZJ7 6 +Premature rupture of membranes 0.53411490534007 0.819465360063998 0.4125209576170849 1.0 0.9742189419579792 6 O75844 1 +Stenosis of the external auditory canal 0.5013967631417225 0.8181358082496352 0.4132796440859216 1.0 0.9742189419579792 8 O95202,P16435,P55011 3 +Anorexia 0.4054814784392154 0.8179290257814426 0.4133977152456831 1.0 0.9742189419579792 29 P10644,P04062,Q13423,P06280,Q5HYI8,Q9NZ08,Q14108,P15260 8 +Extrapyramidal muscular rigidity 0.5336790969041416 0.8173630488351877 0.4137209857567052 1.0 0.9742189419579792 6 Q9BPX6,O75787 2 +Steppage gait 0.399109144321996 0.8161232658209586 0.4144296384755601 1.0 0.9753897562692648 20 P56192,Q13501,Q6DD88,P05023,O15269,P07196 6 +Limb myoclonus 0.5718182265736402 0.8148293355037349 0.4151700065411301 1.0 0.975458743666028 5 P11166 1 +Abnormality of the peripheral nervous system 0.3240190579808539 0.8128808956321 0.416286348806012 1.0 0.9772666295379814 97 P39210,O00592,Q99519,P07602,Q9NQZ5,P04062,Q99720,Q6DD88,P06280,O95831,Q9Y619,P0DP25,Q9BXW9,Q04656,P07686,Q9NZJ7,P21964,P42892,O76024,O60313,O15269,P07196,P51149 23 +Skin pit 0.448113707393393 0.8119342519358428 0.4168293591553818 1.0 0.9780436590965292 13 Q07954,P16615 2 +Thickened skin 0.3286640869465552 0.8098090689248507 0.4180499195334202 1.0 0.9792904756845444 103 O75844,O95470,Q14126,Q99519,P04062,P40855,Q6DD88,P04066,P53634,P06280,P42167,Q96JJ3,P16278,Q06136,P16615,Q04656,Q15800,Q9NWM8,Q14574,Q14739,Q15555,Q07954,P51648,O15269,P31751 25 +Abnormality of chorioretinal pigmentation 0.5698981748110645 0.8063040906383292 0.4200675324277156 1.0 0.981313959865234 5 Q5XKP0,Q9Y619,P49815 3 +Hyperostosis 0.4063938142828906 0.8038317554798072 0.4214941474054403 1.0 0.9819962131218668 18 P10644,Q92889,P48651,O00754,Q15043 5 +Aplasia hypoplasia involving the skeletal musculature 0.4980881518410124 0.800917927448364 0.4231791608111199 1.0 0.9837307854190216 8 O43505,Q9H9S5 2 +Subcutaneous hemorrhage 0.4015498130259543 0.7961507352041165 0.4259444280161208 1.0 0.9837307854190216 41 P10644,P04062,Q9BXW9,P21964,Q16625,P17612,Q04656,P51798,P38435,Q86YV9,Q99519,Q14108,P49257,Q9NWM8,Q9BZK7 15 +Hemoptysis 0.5675230494715615 0.7957717507036415 0.4261647140384441 1.0 0.9837307854190216 5 Q9NZ08,P01889 2 +Hypogonadotropic hypogonadism 0.4016344839320158 0.7943557151103192 0.4269883773610905 1.0 0.9837307854190216 27 P16870,Q15042,P03886,Q9Y4P3,P03915 5 +Reduced subcutaneous adipose tissue 0.4617048790677391 0.7942145068246581 0.4270705646153159 1.0 0.9837307854190216 10 O75844,Q6NUK1,P36543 3 +Renal dysplasia 0.4451625982239754 0.7938359049582192 0.4272909671990099 1.0 0.9837307854190216 13 O43505,Q9H9S5,Q15526 3 +Impairment of activities of daily living 0.3789644563252809 0.7931975303439783 0.4276627461764961 1.0 0.9837307854190216 59 Q13501,P35637,P21964,Q6DD88,Q99720,Q3ZCQ8,Q10471,P07686,Q8TAA9,P11166,P07602,Q92581,O15269,Q9NZJ7 14 +Elevated circulating follicle stimulating hormone level 0.605591416685838 0.792418992712215 0.4281164086617965 1.0 0.9837307854190216 4 P51809 1 +Mitochondrial respiratory chain defects 0.5666677802818475 0.7919828810309761 0.4283706581043449 1.0 0.9837307854190216 5 P03886,Q4J6C6,P03915 3 +Facial diplegia 0.4787069316439353 0.7913853517535332 0.4287191552550338 1.0 0.9837307854190216 9 P12235 1 +Tongue fasciculations 0.4610563755436342 0.7905411586569573 0.4292117951428893 1.0 0.9837307854190216 10 O95831,Q16637,Q13510 3 +Increased circulating cortisol level 0.6972731502443141 0.7871056853458842 0.4312200015178513 1.0 0.9837307854190216 3 P10644 1 +Retinal dystrophy 0.3884546803475553 0.7868585410966291 0.4313646794905055 1.0 0.9837307854190216 53 P40855,P98164,Q8NHS3,Q15555,P38435,P04114,Q9Y287,P53701,Q9H2C2,O43505,Q9H9S5 11 +Limited knee extension 0.6970467090444803 0.7862517031184412 0.4317200411374147 1.0 0.9837307854190216 3 Q04656 1 +Abnormality of the calf 0.3801271904270619 0.7859582501386907 0.4318919467479114 1.0 0.9837307854190216 58 Q9BV10,P16278,Q04656,P51798,Q9NX62,O95831,P08236,P16435,Q9Y619,O00754,Q8WVQ1,Q7LGA3,Q96HY6 13 +Aplasia hypoplasia of the uterus 0.4216534184388431 0.7849590118656312 0.4324776008013118 1.0 0.9837307854190216 16 O95202,Q16740 2 +Micropenis 0.3720476034583818 0.7846592893137913 0.4326533579427667 1.0 0.9837307854190216 62 Q8TCJ2,O95470,P53701,Q9NP72,Q9H9S5,Q9NVI7,P19022,Q9Y5P6,Q8WWQ0,Q9Y619,P46977,O75419,Q9BXW9,P16870,Q6NUK1,O43505,Q9BZK7,P51809,P42892,Q9BV10,P16435 21 +Proportionate short stature 0.4019512976456305 0.7829456016201429 0.4336590571798804 1.0 0.9837307854190216 34 Q15392,P10644,Q14739,P16278,P10619,Q7RTS9,Q9Y619,P53701,P48651,Q8WVQ1,Q96HY6 11 +Aplasia involving bones of the extremities 0.6031966248813678 0.7826567268074747 0.4338287200302584 1.0 0.9837307854190216 4 Q04656 1 +Frontal balding 0.696010183654819 0.7823449987406385 0.4340118481604411 1.0 0.9837307854190216 3 P11166 1 +Subcutaneous nodule 0.3935055244729163 0.7821787932807568 0.4341095056686248 1.0 0.9837307854190216 19 P35637,P01889,P06280,Q9NZ08,Q13510 5 +Abnormal mitral valve physiology 0.4012204596132909 0.7799677591196028 0.4354098527166159 1.0 0.9845812012655634 37 P04062,O75844,P01889,P06280,P04114,Q9NZ08,P53701,O00754,Q15526,Q9Y4P3,P01130 11 +Preaxial polydactyly 0.4543112079601731 0.779501465200066 0.435684374818619 1.0 0.98471926557486 11 O95202,Q9BXW9,Q9UHX1 3 +Increased circulating antibody level 0.4284645210046193 0.7773078609810145 0.436977158274721 1.0 0.9848746683286972 15 Q14108,P15260 2 +Abnormal serum insulin like growth factor 1 level 0.6946465226858674 0.7772112754131124 0.4370341309492398 1.0 0.9848746683286972 3 Q9BV10 1 +Hepatomegaly 0.3716993996322176 0.7756854045494974 0.4379347597443948 1.0 0.9851863180573686 165 Q9HC07,P61916,Q16625,P09601,P39210,Q9BT22,P51798,Q9Y6M9,Q99519,P07602,Q15526,Q96J02,Q96A33,P54802,P04062,Q9NVI7,P56192,O15118,P40855,P04066,Q9HC21,Q07021,Q9Y619,O00754,P15586,P03886,Q13510,P03915,O75787,P16278,P38571,Q01844,P07686,Q15904,Q86Y39,O43676,Q14108,P23786,P10253,Q96HY6,Q9NZJ7,Q14739,P09622,Q6NUQ1,P08236,P11166,P31751 47 +Limitation of joint mobility 0.3229095088500844 0.7748068034173533 0.4384538285219548 1.0 0.9851863180573686 99 O75844,Q9BT22,Q7LGA3,Q96J02,P54802,Q9HC21,Q8TAA9,O00754,P15586,O14979,P01889,Q15042,P16278,Q04656,Q7RTS9,P23786,P50402,P08236,O76024,P16435,P51648,Q9Y4P3 22 +Psychotic mentation 0.5626165333622772 0.7740640169998618 0.4388929350654948 1.0 0.985692847836966 5 P03886,P03915 2 +Decreased circulating copper concentration 0.7590953785644289 0.7729595625140862 0.4395463126525263 1.0 0.9860243822044108 2 Q15904 1 +Short palpebral fissure 0.3987138515411422 0.771543235822964 0.4403850054310001 1.0 0.9860243822044108 27 O75844,Q9BXW9,Q9UHX1,Q15555,Q6NUK1,Q9Y619 6 +Dysmetria 0.3881787180284828 0.7708000814598819 0.4408254389684187 1.0 0.9861783114657032 52 Q13501,O75787,P98155,O75503,Q8IV08,O14773,Q99519,O60313,Q6DKK2,Q6P4A7 10 +Abnormality of skeletal muscle fiber size 0.4194914640709987 0.7704497767490205 0.4410331360402657 1.0 0.9861783114657032 16 O95831,Q13501,O60313 3 +Hypoplasia of the uterus 0.4916613269528513 0.7675411140004287 0.4427598582671128 1.0 0.9879679256614182 8 Q16740 1 +Cavum septum pellucidum 0.452106914189402 0.7667147519362124 0.4432511307922158 1.0 0.9879679256614182 11 Q9BV10 1 +Nemaline bodies 0.5990409162676251 0.765759452296369 0.4438194447642076 1.0 0.9879679256614182 4 O43676 1 +Foot dorsiflexor weakness 0.3991375201993 0.7650252615486917 0.4442565022693303 1.0 0.9879679256614182 30 P56192,Q13501,Q14739,P39210,Q6DD88,P05023,Q99720,O15269,P07196 9 +Severe global developmental delay 0.3678224238813224 0.7628979460785336 0.4455242612314347 1.0 0.9879679256614182 63 P40855,P55011,Q9BZK7,O00584,Q15067,P00387,Q9BV10,Q9BT22,Q9HC21,P07942,Q7RTS9,Q9UID3,Q92581,Q7LGA3,Q9H490,P03886,Q96A33,P03915 18 +Abnormal tricuspid valve physiology 0.4096655214702249 0.7616083663946304 0.4462937799657402 1.0 0.9879679256614182 17 P10644,Q6NUK1,Q15904,P53701,P36543 5 +Ventricular arrhythmia 0.3992518870780973 0.7612532813828408 0.4465057992907026 1.0 0.9879679256614182 33 P50402,P19022,P12235,P42892,P00403,Q02487,Q14126,P04899,P0DP25,P23786,P03886,P10253,P03915 13 +Broad clavicles 0.690224232869827 0.7606106441675966 0.4468896602004124 1.0 0.9879679256614182 3 Q04656 1 +Hamartoma of tongue 0.7558177646673191 0.7605587848382802 0.4469206450679324 1.0 0.9879679256614182 2 P08754 1 +Abnormal lower limb bone morphology 0.3685504433217504 0.7601746819989048 0.4471501765479033 1.0 0.9879679256614182 162 O75844,P51798,P07602,P15260,Q7LGA3,Q9H9S5,Q96A33,P04062,P04066,P06280,O95831,Q9Y619,O00754,Q13510,P10644,O75787,Q9UHX1,P16278,Q04656,Q10471,O43505,Q96HY6,Q9NZJ7,Q14739,P21964,Q9BV10,Q9Y487,Q9NX62,Q6NUQ1,P08236,P16435,Q8WVQ1,O95202,P13073 34 +Abnormality of the abdominal wall 0.3383316402365569 0.7592347147433992 0.4477121631767449 1.0 0.9879679256614182 120 O75844,Q99519,P04066,O00754,P98164,Q9UHX1,Q96JJ3,P16278,Q5SZK8,Q04656,Q6NUK1,Q96HY6,O00462,Q14739,P21964,Q9Y487,Q15555,P08236,Q8WVQ1,Q9Y4P3 20 +Spastic paraparesis 0.3914274771472994 0.7584451457427864 0.4481845399162887 1.0 0.9879679256614182 20 P04062,Q5XKP0,Q9Y619,O75787 4 +Abnormal hdl cholesterol concentration 0.5958760320667602 0.752929443662994 0.4514923137595601 1.0 0.9900731447231368 4 P38571 1 +Alkalosis 0.5956262733767872 0.7519184237555774 0.4521001178743979 1.0 0.9900731447231368 4 Q9Y619 1 +Facial capillary hemangioma 0.7525401507702573 0.7482110418841542 0.4543328718219706 1.0 0.9900731447231368 2 P16435 1 +Aplasia hypoplasia of the earlobes 0.4706166411832128 0.7475900039538873 0.4547074959520731 1.0 0.9900731447231368 9 P21964 1 +Atresia of the external auditory canal 0.4158200147533276 0.7458387462898091 0.4557648309683815 1.0 0.9900731447231368 16 Q5SZK8,Q9H9S5 2 +Autoamputation 0.5184816461871662 0.7443403584829 0.4566705909942903 1.0 0.9900731447231368 6 P39210,O15269 2 +Functional abnormality of male internal genitalia 0.393893040087683 0.7436740987694497 0.4570736628369296 1.0 0.9900731447231368 25 P04062,P51809,Q13423,O76024,P16435,Q9Y4P3 6 +Cirrhosis 0.3962936057934327 0.7408361186605633 0.458792812425512 1.0 0.9900731447231368 38 P04062,P56192,O75787,P39210,P38571,P11717,Q15904,Q14108,Q96J02 9 +Iris coloboma 0.3967632938975054 0.7405595528692759 0.4589605399424703 1.0 0.9900731447231368 34 P98164,Q9UHX1,O95202,O43505,Q9H9S5 5 +Alveolar cell carcinoma 0.750245821042301 0.7396000170053479 0.4595427313534137 1.0 0.9900731447231368 2 P00533 1 +Abnormality of circulating glucocorticoid level 0.4361006749573756 0.7383838365042437 0.4602812339185425 1.0 0.9900731447231368 13 P10644,P16435,Q13423 3 +Specific learning disability 0.3585673100364137 0.7371598178358216 0.4610251659680537 1.0 0.9900731447231368 66 Q13501,P53701,Q9H6K4,Q9H9S5,P42345,Q9Y619,O00754,Q9BPX6,P03886,P03915,P10644,O75419,P04350,Q04656,P00403,P49815,O43505,P35637,P21964,P11166,P48651 21 +Torsion dystonia 0.6838575681647381 0.7368450037467283 0.4612166117489304 1.0 0.9900731447231368 3 P11166 1 +Hyperextensible skin 0.4218492809094212 0.7343714768025816 0.462722365845484 1.0 0.9900731447231368 15 P04062,Q04656,Q9UHX1 3 +Periventricular cysts 0.5159575921846005 0.7322746339357926 0.4640009585552898 1.0 0.9900731447231368 6 O95202 1 +Median cleft palate 0.7482792527040508 0.7322408469708866 0.4640215769375895 1.0 0.9900731447231368 2 Q14739 1 +Septo optic dysplasia 0.7482792527040283 0.732240846970803 0.4640215769376405 1.0 0.9900731447231368 2 Q8WWQ0 1 +Hypoplastic heart 0.7482792527040281 0.7322408469708008 0.4640215769376419 1.0 0.9900731447231368 2 O60826 1 +Low alkaline phosphatase 0.5907387514381213 0.7321786375180158 0.464059541382352 1.0 0.9900731447231368 4 P38571 1 +Hypopigmentation of the skin 0.3864997696005166 0.7312296831673749 0.4646388722932055 1.0 0.9900731447231368 50 Q9BXW9,P21964,Q96C86,Q9NZJ7,P53634,Q04656,P51798,P42345,Q92889,Q86YV9,P53701,P07602,P49815,Q8IZA0,P18074 15 +Generalized myoclonic seizure 0.3934094570655259 0.7306637952801626 0.4649845348579537 1.0 0.9900731447231368 42 P04062,Q96N66,Q8NHS3,P16278,Q99519,Q9Y619,P07602,Q01105,P11166,P03886,Q13510,Q9NZJ7 12 +Lacrimation abnormality 0.396039740054521 0.7294126011608457 0.4657493119444824 1.0 0.9900731447231368 18 Q07954,Q9Y4P3,P55011 3 +Developmental regression 0.3398899246632157 0.7285353201179647 0.466285955720547 1.0 0.9900731447231368 125 O95470,Q99519,P07602,Q15526,Q15043,P40855,P06280,O95831,Q9NZ08,P03886,Q13510,P03915,P01889,P16278,P55795,Q04656,P07686,Q92581,Q9H2C2,P17900,Q9NZJ7,O75503,O14773,O76024,Q9Y4P3,P13073 26 +Slender long bone 0.4205403817116698 0.7258914369676026 0.4679053263734616 1.0 0.9900731447231368 15 Q9Y487,Q9Y619,Q96J02,Q9H490,O75419 5 +Aplasia hypoplasia of the ribs 0.3890858120582829 0.7257316764734069 0.4680032789277364 1.0 0.9900731447231368 22 Q9UHX1,Q9BV10,Q8TAA9,Q9Y619,Q96HY6 5 +Aplasia hypoplasia of the clavicles 0.4204468044351128 0.7252853879129226 0.4682769681035656 1.0 0.9900731447231368 15 O75844,Q9Y619 2 +Zonular cataract 0.4494158452779159 0.7247670377176757 0.4685949607327511 1.0 0.9900731447231368 10 O76024,P11166,Q99797,Q9H6K4,P08670 5 +Microcytic anemia 0.5140174401769548 0.7230138899904982 0.4696713506341783 1.0 0.9900731447231368 6 Q9UBX3 1 +Distal joint laxity 0.6799999999999942 0.7225262047670556 0.4699710202345735 1.0 0.9900731447231368 3 O75340,Q9H553 2 +Cortical cataract 0.6796721311475374 0.7213121107397532 0.4707175073851011 1.0 0.9900731447231368 3 Q99797,Q9H6K4 2 +Metaphyseal dysplasia 0.4390379177259932 0.7209634002552286 0.4709320333617759 1.0 0.9900731447231368 12 Q9HC07,O95831 2 +Generalized osteosclerosis 0.679231794484791 0.7196822790741818 0.4717206395070028 1.0 0.9900731447231368 3 P51798 1 +Abnormality of the gastric mucosa 0.4193826308169076 0.7183953978629543 0.4725135236352895 1.0 0.9900731447231368 15 P04062,Q14739,O76024 3 +Cachexia 0.3858861644453655 0.7169472717987042 0.473406632214427 1.0 0.9900731447231368 20 P04062,P38571,Q99720,Q01844,P07602,Q92581,Q9NZJ7 7 +Bowing of the legs 0.3860621602787652 0.7167414019793313 0.4735336744721472 1.0 0.9900731447231368 49 P16278,Q04656,P51798,Q9NX62,P08236,P16435,Q9Y619,O00754,Q8WVQ1,Q7LGA3,Q96HY6 11 +Hypoplastic female external genitalia 0.4114682449610142 0.7167212952190279 0.4735460833581157 1.0 0.9900731447231368 16 Q15042,Q6NUK1,P16435,Q9Y619,O75419 5 +Abnormal middle phalanx morphology of the hand 0.4818263312876077 0.7166733499085022 0.473575673525362 1.0 0.9900731447231368 8 Q9UHX1 1 +Waddling gait 0.3921000061589014 0.715807103875271 0.47411046535734 1.0 0.9900731447231368 28 P50402,Q5T8D3,Q9BTV4,Q4J6C6,Q7RTS9,Q9H553,Q9Y6X9,Q9Y5P6,P53007,Q8WVQ1,P07196,Q9H9S5,Q13510 13 +Eeg with spike wave complexes 0.4380300954098768 0.7149869396763396 0.4746171134914561 1.0 0.9902923853777196 12 O75503,Q14108 2 +Spastic diplegia 0.3893756975905735 0.714743722051433 0.4747674158582571 1.0 0.9902923853777196 24 Q15042,Q99720,P07602,P51648,Q9NZJ7 5 +Osteolysis 0.3929050285704971 0.713031061330055 0.4758265366498644 1.0 0.990965152851388 31 O75844,Q13501,Q96JJ3,P53634,Q04656,Q14108,O00754 7 +Status epilepticus with prominent motor symptoms 0.7423795476893038 0.710287164618266 0.4775260776482695 1.0 0.9922647730592196 2 Q13510 1 +Delayed eruption of primary teeth 0.6750819672131059 0.7043641271790362 0.4812060400327418 1.0 0.9945356015551244 3 Q92889,Q13045 2 +Abnormal pyramidal sign 0.3333140752367291 0.700674453082495 0.4835062026348315 1.0 0.9947150583115024 119 O75569,Q13501,P51572,Q9P0J0,O00592,P07602,Q9H6K4,Q15043,Q9H9S5,Q15067,Q99720,P04066,O95831,Q9NZ08,Q9Y619,O00754,O75787,P01889,Q6PJG6,P17900,Q6DKK2,Q9NZJ7,P35637,O00429,O14773,P11166,O60313,P51648,P07196,O00400,Q96CW1 31 +Overriding aorta 0.4955356793012768 0.7005927338016 0.4835572143288731 1.0 0.9947150583115024 7 P53701 1 +Femoral bowing 0.4787008935836237 0.7005703899239242 0.4835711625745018 1.0 0.9947150583115024 8 P16435,Q7RTS9,O00754 3 +Action tremor 0.3793999907757068 0.7002891048353269 0.4837467744725356 1.0 0.9947150583115024 53 O75569,O75787,P04350,Q9NZJ7,P35637,P98155,Q99720,O14773,Q9Y287,P07602,Q14108,Q9H6K4,P03886,P03915 14 +Pneumothorax 0.5092216492963018 0.700177094672588 0.4838167142854028 1.0 0.9947150583115024 6 Q6NUK1,P36543 2 +Short nose 0.3125867580799105 0.6992263246932584 0.4844106015717508 1.0 0.994973124163519 93 P10644,P04062,O75844,P98164,P42892,Q9UHX1,Q15042,Q9Y487,Q6NUK1,Q9NX62,P38435,P16435,Q8WVQ1,Q5KU26,Q9H490,Q9Y4P3,P36543 17 +Premature skin wrinkling 0.383419167269732 0.6985102230791896 0.4848581667963032 1.0 0.994973124163519 20 O75844,P11166,Q6NUK1,Q9Y487 4 +Thickened nuchal skin fold 0.4352148885265869 0.6983103040656765 0.484983156648362 1.0 0.994973124163519 12 Q13501 1 +Abnormal sharpey fiber morphology 0.544913799391916 0.6963875524256126 0.486186156255344 1.0 0.995390586082954 5 Q04656 1 +Abnormal vascular physiology 0.3801069237792657 0.6943778150104064 0.4874453027375711 1.0 0.9962639762116966 52 P04062,O75844,Q14739,P01889,P06280,P51798,Q6NUK1,O96000,P00403,Q9NZ08,Q14108,Q8IZA0,Q9Y4P3,P03886,P05067,P03915 16 +Absent toe 0.382774284607775 0.6936950497064459 0.4878734711168919 1.0 0.9962639762116966 20 Q7LGA3,O95202,Q9UHX1 3 +Paroxysmal involuntary eye movements 0.3997854669301424 0.6932511771388736 0.4881519364779549 1.0 0.9963915411384098 17 O96000,Q9Y6M9,Q86Y39,P11166,O43676,P03886 6 +Raynaud phenomenon 0.5070699351387506 0.6899576485368676 0.4902208210192209 1.0 0.9992879572963616 6 O75844 1 +Abnormality of salivation 0.386569486956375 0.6880960211167199 0.4913923159410485 1.0 0.9997399564047696 45 Q14739,Q13501,P55011,O75787,P01889,P35637,Q15165,P55795,Q68CQ7,Q92581,P15586 11 +Anotia 0.5794295964647078 0.6868545045301648 0.4921744189523991 1.0 0.9997399564047696 4 Q9Y619 1 +Fever 0.3041952161039566 0.6864852294280659 0.4924071754405117 1.0 0.9997399564047696 84 Q9HC07,P10644,Q14739,P01889,P38571,P06280,Q9NZ08,P07602,P15260,P23786,P03886,P10253,Q13510,Q9NZJ7 14 +Olivopontocerebellar hypoplasia 0.5424754842072554 0.6857790293253564 0.4928524622613777 1.0 0.9997399564047696 5 Q9H9S5,Q9Y5P6 2 +Hyperthyroidism 0.4424387183711943 0.6855249872143137 0.4930126985216014 1.0 0.9997399564047696 10 P12235 1 +Progressive hearing impairment 0.4271832750480017 0.684051053397281 0.4939429281374159 1.0 0.9997399564047696 13 O76024,P03886,O60313,P03915 4 +Easy fatigability 0.3814646176065193 0.6839219798858092 0.4940244337568464 1.0 0.9997399564047696 20 P10644,P12235,Q9Y5P6,P53007,Q15526,Q9NWM8,Q53H12 7 +Hypoplastic nipples 0.4420655421096812 0.6834307064008402 0.4943347223901611 1.0 0.9997399564047696 10 Q96A33,P10586 2 +Varicose veins 0.5051646190790174 0.6809230179449225 0.4959202024947307 1.0 1.0 6 P21964 1 +Abnormality of the bladder 0.3280222304192361 0.6807607974066854 0.4960228594144218 1.0 1.0 114 Q13501,P07602,P04062,Q99720,Q8TAA9,Q9UHX1,P01889,Q5SZK8,Q04656,Q10471,P07686,Q92581,Q9NWM8,Q9NZJ7,P12235,P21964,P35637,Q3ZCQ8,O76024,Q86XL3,P11166,P16435,Q9Y4P3 23 +Leukoencephalopathy 0.305412819650798 0.6800214601509993 0.4964908727430781 1.0 1.0 86 Q15526,Q9UHX1,O00584,O75503,P07942,O96000,Q9Y6M9,O95831,Q86Y39,O43676,P07602,O60313,P17900,Q01105,O95202,P03886,Q9H9S5,Q9NZJ7 18 +Aplasia hypoplasia involving bones of the thorax 0.389143295723213 0.6792669526291062 0.4969687317662963 1.0 1.0 37 O75844,Q14739,Q9UHX1,Q9BV10,Q04656,Q7RTS9,Q8TAA9,Q9Y619,P16435,Q96HY6 10 +Abnormality of primary teeth 0.388890632741075 0.6782467203046306 0.4976152742127846 1.0 1.0 18 O75844,P53634 2 +Aplasia hypoplasia affecting the fundus 0.3826324200681801 0.6769947126162628 0.4984093090904822 1.0 1.0 22 Q9NVI7,Q9UHX1,Q9Y5P6,Q86YV9,Q99519,P07196,Q9H9S5 7 +Dermal atrophy 0.3859603206936264 0.6722224246245037 0.501442107080841 1.0 1.0 27 Q15392,P10644,O75844,P53634,Q07954,P53701,Q9NWM8 7 +Positional foot deformity 0.3089234172734621 0.6710097708720378 0.502214305041806 1.0 1.0 91 Q96A33,Q9NVI7,Q9HC21,Q8TAA9,Q9Y619,O00754,Q9UHX1,Q7RTS9,Q9NWM8,P21964,Q9BV10,Q9Y487,Q6NUQ1,P08236,P16435,Q8WVQ1,P07196,O95202,P36543 19 +Abnormality of hepatobiliary system physiology 0.3224742248134497 0.6706812110156241 0.5024236348088316 1.0 1.0 77 Q16625,P39210,Q9BT22,Q8N511,Q15526,Q96J02,Q96A33,P04062,P56192,O15118,P40855,Q9Y619,P03886,Q13510,P03915,O75787,P01889,P38571,P23786,O95169,P09622,Q6NUQ1,Q5XKP0 23 +Exercise induced muscle stiffness 0.7309078990495137 0.668161239503779 0.5040306743781566 1.0 1.0 2 P46020 1 +Simple ear 0.5378577102245108 0.6657559642363703 0.5055670958280578 1.0 1.0 5 P16435 1 +Crumpled long bones 0.7299246148803861 0.6645867618633188 0.5063148387318308 1.0 1.0 2 P07237 1 +Platybasia 0.4880547126985647 0.663806284131512 0.5068143031354193 1.0 1.0 7 P14543 1 +Progressive cerebellar ataxia 0.3873543818877026 0.6636022095615887 0.5069449427434962 1.0 1.0 36 Q13501,P35637,Q9Y487,Q7KZN9,Q9P0J0,O76024,O14773,Q9Y619,Q15526 9 +Abnormality of the nasal tip 0.3140380011729207 0.662559552954478 0.5076126819310272 1.0 1.0 98 P10644,O75844,P98164,P42892,Q9UHX1,P21964,P16278,P10586,Q15042,Q9Y487,O95831,P16435,Q86UE8,Q7LGA3,P23786,Q96A33 16 +Irregular capital femoral epiphysis 0.7289413307112382 0.6610182292136064 0.508600623170461 1.0 1.0 2 P50542 1 +Nasal regurgitation 0.7286135693215301 0.6598300475418747 0.5093628986434582 1.0 1.0 2 P53007 1 +Short long bone 0.38676926656941 0.6591271281653821 0.5098141366053777 1.0 1.0 34 P10644,Q9BXW9,Q9UHX1,Q9BV10,P16278,Q04656,Q8WVQ1,Q96HY6 8 +Abnormality of the septum pellucidum 0.3859883251376422 0.6590200923482781 0.5098828664244683 1.0 1.0 40 Q96N66,P55011,Q96C86,Q9BV10,Q9NZ01,P48651,P53701,O95202,O43505,Q9H9S5 10 +Abnormal leukocyte physiology 0.3600507475910603 0.6585873402693996 0.5101607945315292 1.0 1.0 62 P04062,P21964,P02786,P09601,Q9BV10,Q15904,Q14108,P15260,O00754,Q96J02 10 +Abnormal pulmonary thoracic imaging finding 0.3811030442463368 0.658310964964946 0.5103383336096363 1.0 1.0 23 P04062,P21964,Q9NZ08,P15260,Q13510 5 +Micronodular cirrhosis 0.4866550838408421 0.656948240886861 0.5112141979620608 1.0 1.0 7 P11717 1 +Protrusio acetabuli 0.6616393442622909 0.6552930879893183 0.5122790701801845 1.0 1.0 3 O75718,Q02809 2 +Overlapping toe 0.3855616931980299 0.6545013720138133 0.512788843498091 1.0 1.0 18 Q96A33,Q9UHX1,Q15042,Q9Y4P8 4 +Poikiloderma 0.4995312312998747 0.6542953850557254 0.5129215185452236 1.0 1.0 6 O75431,Q92889,P18074 3 +Esophageal varix 0.6610277937616951 0.653081820323459 0.5137035317175065 1.0 1.0 3 P04062 1 +Abnormal exteroceptive sensation 0.3801216071012893 0.6530752761528312 0.5137077504196219 1.0 1.0 48 P54802,P01889,P39210,P06280,P07686,O95831,Q9NZ08,P11166,P07602,O15269,P05067,Q9NZJ7 12 +Gynecomastia 0.3853007561791551 0.6526425322195629 0.513986758974341 1.0 1.0 18 P16870,P31751 2 +Epiphyseal dysplasia 0.4855978860319999 0.6517735030363734 0.5145472973389813 1.0 1.0 7 Q9HC07,Q8WVQ1 2 +Dysphasia 0.3850450752780938 0.6508214924675754 0.5151617245973783 1.0 1.0 18 P21964,Q13501 2 +Penetrating foot ulcers 0.6597113943512625 0.6483284752154522 0.5167725204779114 1.0 1.0 3 O15269 1 +Emg slow motor conduction 0.6597113943512625 0.6483284752154522 0.5167725204779114 1.0 1.0 3 O15269 1 +Trophic changes related to pain 0.6597113943512625 0.6483284752154522 0.5167725204779114 1.0 1.0 3 O15269 1 +Increased blood pressure 0.3175174541192581 0.6476687720225719 0.5171992061259492 1.0 1.0 78 P10644,P04062,O75844,P21964,P42892,P01889,P38571,P06280,P00533,P15529,P04114,Q8TAA9,P16435,P03886,Q9Y4P3,Q96J02,P01130,P03915 18 +Abnormal lymphocyte morphology 0.3853942542290448 0.647438303410271 0.5173483125840765 1.0 1.0 36 O75787,Q9BV10,P16278,P04066,Q99519,O00754 6 +Abnormalities of placenta or umbilical cord 0.4010506180751031 0.6473177905725475 0.5174262897284987 1.0 1.0 16 P16278,P15529,O75844 3 +Abnormal muscle fiber protein expression 0.4845110825289481 0.6464588281342171 0.5179822526371192 1.0 1.0 7 P50402,Q9H9S5,Q9Y5P6 3 +Atlantoaxial abnormality 0.5691897614682663 0.6462885487917656 0.518092502520159 1.0 1.0 4 Q7RTS9 1 +Athetosis 0.4148061471160603 0.6457601081159939 0.5184347265131399 1.0 1.0 14 O00584 1 +J shaped sella turcica 0.5683019380671986 0.6427944806745802 0.5203574649575899 1.0 1.0 4 Q96AX1,P08236 2 +Abnormal male reproductive system physiology 0.3841870848363849 0.637492359409822 0.5238041852396309 1.0 1.0 36 P04062,P51809,Q13423,P07686,O76024,O00592,P16435,Q9Y4P3 8 +Respiratory tract infection 0.3547701478595498 0.6373848184944098 0.5238742147026219 1.0 1.0 155 P09601,P51798,Q99519,P07602,P15260,Q96J02,Q13277,P54802,P04062,P02786,P04066,P53634,O00754,P15586,Q13510,P01889,P16278,Q6NUK1,P00533,P10253,Q9NZJ7,O00462,Q9BV10,Q9Y487,Q03518,Q8NFH4,P08236,O95202 28 +Abnormality of secondary sexual hair 0.4500454980755824 0.6371284919782245 0.5240411510704832 1.0 1.0 9 Q02487,P51809,Q14574 3 +Abnormality of humoral immunity 0.3700145927524575 0.6370178751813731 0.5241132002888755 1.0 1.0 55 P04062,P02786,P09601,Q9BV10,Q15904,Q14108,P15260,O00754,Q96J02 9 +Deformed tarsal bones 0.7210750573582674 0.6326896497254213 0.5269363301918282 1.0 1.0 2 O75787 1 +Abnormal shape of the palpebral fissure 0.4184097855820033 0.6308971784332299 0.5281077568661496 1.0 1.0 13 P55795,Q9BXW9,Q9UHX1 3 +Abnormal talus morphology 0.3822158292452203 0.6306951795828308 0.5282398515203517 1.0 1.0 18 Q969X5,O75844,Q9UHX1,Q9UPT5,P98175,Q99567,Q9Y263,P16435,O43175,P18074 10 +Abnormal motor evoked potentials 0.7204195345788369 0.6303470066392138 0.5284675744207363 1.0 1.0 2 P07196 1 +Exercise intolerance 0.3828325984531683 0.6303381297908212 0.5284733809867814 1.0 1.0 32 P12235,Q9Y2R0,Q07021,P00403,Q9H2D1,Q15526,P23786,P03886,P46020,P03915 10 +Spinal muscular atrophy 0.4325633920481964 0.6302871207334537 0.5285067479023393 1.0 1.0 10 Q99720,Q04656,Q13510 3 +Abnormal systemic arterial morphology 0.3457570270440475 0.628604375376987 0.5296080951507409 1.0 1.0 143 O75844,P61916,P55011,P10619,P04114,Q99519,P07602,P53701,Q7LGA3,P05067,Q96PU5,P04062,O15118,P19022,P01130,P03886,Q13510,P03915,P10644,Q9UHX1,P01889,P16278,P06865,P38571,Q04656,Q6NUK1,P07686,P17900,P10253,Q9NZJ7,P21964,P38435,Q9Y4P3 33 +Aplasia hypoplasia of the tongue 0.5291885220023138 0.6284238247951713 0.5297263337522669 1.0 1.0 5 P48651,P08754 2 +Supernumerary nipple 0.4317262776411952 0.6256237378605383 0.5315617650668669 1.0 1.0 10 Q7LGA3 1 +Abnormal pharynx morphology 0.3818840170286223 0.6241478437317896 0.5325304958467627 1.0 1.0 40 P54802,P01889,Q9BV10,P16278,Q03518,P08236,P15586,Q13277,Q13510 9 +Shield chest 0.4930618781045539 0.6238858246872662 0.5327025703138086 1.0 1.0 6 P04066 1 +Hydrocele testis 0.4928304618939518 0.622801633214843 0.5334148849486544 1.0 1.0 6 Q9UBX3 1 +Neoplasm of fatty tissue 0.4311789637758302 0.6225765273087863 0.5335628400392467 1.0 1.0 10 Q9BUK6,P27635,Q8TAA9,P53680,P03915 5 +Upper limb spasticity 0.462806797811172 0.6192572138692305 0.5357469260764001 1.0 1.0 8 Q99720,P35637,Q9BTW9 3 +Frequent falls 0.3815995612337355 0.6176803503168099 0.5367860672183182 1.0 1.0 38 P04062,O75787,P12235,P07602,Q9H9S5,Q13510 6 +Abnormal periventricular white matter morphology 0.3816383875633527 0.6165175129951034 0.5375530170044391 1.0 1.0 36 Q9UHX1,O75503,P07602,P17900,O95202,Q9H9S5,Q9NZJ7 7 +Onychogryposis 0.6506242784499913 0.6157680166305661 0.5380476391587843 1.0 1.0 3 P53634 1 +Ocular pain 0.6506036296395806 0.6156945457632612 0.5380961377672615 1.0 1.0 3 Q15043 1 +Long upper lip 0.7148475909537824 0.6105509246254929 0.5414969202533702 1.0 1.0 2 Q9BZK7 1 +Secondary microcephaly 0.3292714884190891 0.6080334508136129 0.5431652883139844 1.0 1.0 73 Q9HC07,Q5T8D3,Q9BT22,Q96CU9,Q15043,Q9NP72,O95630,Q9NVC6,Q9HC21,P50897,O75419,Q9UHX1,P55795,Q6PJG6,Q86Y39,P00374,Q9Y487,Q9BV10,P11166,Q5KU26,Q5XKP0,P36543 22 +Hammertoe 0.3789460968970223 0.6074951994725295 0.5435223274962806 1.0 1.0 18 P39210,Q96BR5,Q99720,Q9Y6X9,Q8N0X7,Q9UBM7,P07196,P51149 8 +Axial dystonia 0.6482726195614482 0.6074161137765992 0.5435747973863698 1.0 1.0 3 Q99720 1 +Pelvic girdle muscle weakness 0.4597734145734148 0.6038659017577724 0.5459328005057169 1.0 1.0 8 Q9H9S5 1 +Ectropion of lower eyelids 0.7125532612258232 0.6024614457465903 0.5468670193435583 1.0 1.0 2 O60716 1 +Abnormal gastrointestinal motility 0.3772627924590291 0.6000493344894816 0.5484733570554425 1.0 1.0 28 Q01844,P06280,P00403,Q5HYI8,O76024,P03886,P03915 7 +Abnormal circulating creatinine concentration 0.4878516739637331 0.5995398818973444 0.5488129231652241 1.0 1.0 6 P15529 1 +Abnormal labia morphology 0.3688177755499529 0.5990259702359058 0.5491555664820083 1.0 1.0 19 P51809,Q9Y619,Q6NUK1,Q15042 4 +Rieger anomaly 0.5220615260958126 0.598009897971935 0.5498333286980279 1.0 1.0 5 O95202 1 +Synostosis of joints 0.3792251450856268 0.5978691407930663 0.5499272520535152 1.0 1.0 38 Q9UHX1,Q04656,P16435,Q8TAA9,Q8WVQ1,O95202,Q9H9S5 7 +Focal t2 hyperintense brainstem lesion 0.3999860345749513 0.5936591794394396 0.5527400907107203 1.0 1.0 15 O96000,Q9Y6M9,Q86Y39,O43676,P03886 5 +Fibrosarcoma 0.6436065573770462 0.590939532929521 0.5545609364697142 1.0 1.0 3 P35222,Q13126 2 +Abnormality of fibula morphology 0.4169030346059937 0.5906268729185907 0.554770455091325 1.0 1.0 12 Q04656,Q96HY6,Q8WVQ1 3 +Beaking of vertebral bodies 0.4213741474499189 0.5900801496627325 0.555136916327708 1.0 1.0 11 P16278,P08236,P04066,Q6NUQ1 4 +Abnormality of facial soft tissue 0.3229877494690532 0.5898764607799373 0.5552734764796732 1.0 1.0 116 O75844,Q13501,P51798,O00592,Q99519,Q15526,Q9H9S5,P04062,P40855,O00754,Q13510,O75787,Q9UHX1,P10253,P12235,Q8NFH4,P16435,O60313,Q9Y4P3 19 +Diplopia 0.3697762740398894 0.5886078955025363 0.556124336196044 1.0 1.0 21 P04062,O00592,P11166,O14773 4 +Neuropathic arthropathy 0.5543214897521541 0.5883089849597264 0.5563249158245742 1.0 1.0 4 O15269 1 +Gastrointestinal obstruction 0.3914641672175492 0.583938693713782 0.5592615591439385 1.0 1.0 16 Q5HYI8,P42892 2 +Ascending tubular aorta aneurysm 0.4843596563486875 0.5833009848579734 0.5596906996640967 1.0 1.0 6 O75844 1 +Skeletal dysplasia 0.3762727518915766 0.5826012684759866 0.5601617512961474 1.0 1.0 42 Q9HC07,Q14739,P40855,P16278,P10619,O95831,Q99519,P51648,Q8WVQ1,P07237,Q96HY6 11 +Abnormal retinal morphology 0.3867581588379681 0.5820664139922501 0.5605219468197162 1.0 1.0 213 P55011,P10619,Q7KZN9,P04114,Q9P0J0,Q99519,Q9Y287,P07602,P53701,Q7LGA3,Q9H9S5,P04062,P40855,Q8NHS3,Q9UG56,Q9NZ08,Q9Y619,P50897,O00754,Q9Y6B6,P03886,Q13510,P98164,Q9UHX1,Q96JJ3,P01889,P16278,P06865,Q15042,P07686,Q9H2C2,P17900,O43505,Q9NZJ7,P21964,Q9BV10,O75503,P04439,Q9Y487,Q15555,P38435,O14773,O76024,O60313,P51648,O95202,Q5XKP0,Q9Y4P3,P36543 49 +Hypoplasia of the brainstem 0.3764215490557077 0.5819688720091298 0.5605876481557164 1.0 1.0 31 Q96EK5,Q9UPT5,P98155,Q9Y5P6,Q9Y320,P07942,O43505,Q9H9S5,O60508 9 +Retinal neovascularization 0.7066535562110734 0.5818313405547648 0.5606802915293678 1.0 1.0 2 O15484 1 +Vitreoretinopathy 0.7066535562110734 0.5818313405547648 0.5606802915293678 1.0 1.0 2 O15484 1 +Deviation of the hallux 0.3747659182043097 0.5806911003286417 0.5614486608871512 1.0 1.0 28 P04062,P55011,Q7LGA3,Q96J02,Q9Y4P3 5 +Pruritus 0.3697550368683654 0.5803987471620761 0.5616457498050373 1.0 1.0 22 P38571,P16615,Q07954,Q13277,Q96A33 5 +Emg myopathic abnormalities 0.3739727423790792 0.5795523325885367 0.5622165459280266 1.0 1.0 27 Q13501,P12235,Q9H9S5,Q9Y6B6,P50402 5 +Abdominal pain 0.299022602124526 0.5785142797648114 0.5629169593650547 1.0 1.0 87 P10644,P04062,Q13423,P42892,P01889,Q70HW3,Q04656,P06280,Q8NFH4,P07686,Q5HYI8,P15529,Q9NZ08,Q14108,P23786 15 +Spastic paraparetic gait 0.5514895148677164 0.5774028196397091 0.5636673698937706 1.0 1.0 4 O75787 1 +Retinal vascular tortuosity 0.4036780297209479 0.5767555287557028 0.5641046151354294 1.0 1.0 14 Q9Y4P3,P21964,P03886 3 +Abnormality of circulating fibrinogen 0.4228994070463964 0.576661795699261 0.564167945387057 1.0 1.0 10 P10644 1 +Retinal atrophy 0.3727885652655665 0.5760020448779685 0.5646137994183293 1.0 1.0 26 P04062,P04439,P51648,Q7LGA3,Q9H9S5 5 +Enuresis 0.7046869878728238 0.5750108609619112 0.5652839516411017 1.0 1.0 2 Q92796 1 +Cortical dysplasia 0.373992874876749 0.5747064894889172 0.5654898178121568 1.0 1.0 28 Q96N66,P55011,Q96C86,P42345,Q9NZ01,O43505,Q96PU5 7 +Temporal cortical atrophy 0.5507267845915549 0.5744734962935927 0.5656474305604595 1.0 1.0 4 P00387,O43924 2 +Hypertensive crisis 0.4821368113985904 0.5729987670033747 0.566645528824135 1.0 1.0 6 P21964 1 +Optic nerve hypoplasia 0.4028984004439506 0.5719482859695787 0.5673570101086003 1.0 1.0 14 Q9NVI7,Q9UHX1,Q9Y5P6,Q8WWQ0,P07196,Q9H9S5 6 +Hypointensity of cerebral white matter on mri 0.4819071977478412 0.5719361595385829 0.5673652257279764 1.0 1.0 6 P07602 1 +Skin dimple 0.3695765076056568 0.5714704460881865 0.5676807882529391 1.0 1.0 23 O95202,Q8TAA9,P53701 3 +Protruding tongue 0.4178782704780895 0.5702564008200802 0.5685038072977704 1.0 1.0 11 O60826,Q99519,Q6NUK1 3 +Male sexual dysfunction 0.4134025239105371 0.5702347079430086 0.5685185184022048 1.0 1.0 12 O00592 1 +Abnormal aortic valve morphology 0.3754885157728623 0.5699825001015333 0.5686895674339429 1.0 1.0 40 P04062,O75844,P21964,P01889,Q9UHX1,P06280,Q6NUK1,Q9Y4P3 8 +Apraxia 0.3514873792207423 0.5687386744216664 0.5695334978108542 1.0 1.0 62 P04062,Q13501,P55011,O75787,P35637,O43292,O14773,P11166,Q9Y619,Q92673,Q7LGA3,Q6DKK2,P05067 13 +Death in infancy 0.3600676616333111 0.5686626426542623 0.5695851044160927 1.0 1.0 57 Q9BT22,P07602,Q13277,P04062,P40855,Q15067,Q9HC21,Q8WWQ0,P16278,P38571,Q5SZK8,Q6PJG6,Q6NUK1,Q15904,Q9NZJ7,O75381,O60826,O00429,O60508 19 +Alveolar ridge overgrowth 0.7027204195345937 0.5682191600823353 0.569886162921788 1.0 1.0 2 Q15392 1 +Tongue nodules 0.702720419534574 0.5682191600822679 0.5698861629218337 1.0 1.0 2 O43924 1 +Lung adenocarcinoma 0.5490502801236845 0.5680469262816611 0.5700031044357534 1.0 1.0 4 P30154,P00533 2 +Dilatation of the ventricular cavity 0.7023926581448656 0.5670900361444519 0.5706530120473414 1.0 1.0 2 Q9Y5P6 1 +Spondyloepiphyseal dysplasia 0.7023926581448656 0.5670900361444519 0.5706530120473414 1.0 1.0 2 Q9NSE4 1 +Recurrent bronchitis 0.5140855392710971 0.5643018112349651 0.5725487489849939 1.0 1.0 5 Q03518 1 +Osteolysis involving bones of the upper limbs 0.4519113989488909 0.5641986914522948 0.5726189182731793 1.0 1.0 8 O75844,P53634 2 +Hypocalcemia 0.3950501784286682 0.5622453840240302 0.573948843951573 1.0 1.0 15 P10644,P21964,Q9BV10 3 +Muscle spasm 0.3622662284372328 0.5617381478804101 0.5742944390759712 1.0 1.0 55 P04062,Q13501,P35637,P12235,Q15165,P05023,P09622,P06280,Q68CQ7,O00592,Q16637,Q92804,P07196,P23786,Q9H9S5 15 +Cerebellar atrophy 0.32848316379327 0.5614017881004488 0.5745236653450803 1.0 1.0 126 Q13501,Q8TCJ2,P51572,Q9BT22,P51798,Q8IV08,Q96CU9,Q9H6K4,Q15043,Q9H9S5,Q9NVI7,P98155,Q8NHS3,O00754,Q9Y320,Q9H490,P46977,O75787,P04350,P00387,Q6PJG6,Q14108,Q92581,Q92643,Q6DKK2,P12235,O75503,O00429,O43292,O14773,O60313,Q5XKP0,O00400,P13073 34 +Breech presentation 0.4509965784560129 0.5596055968316428 0.5757484864810007 1.0 1.0 8 Q969X5,O60313,Q9Y619,Q9UBM7 4 +Arrhinencephaly 0.4115117528396178 0.5592508302845248 0.5759905472097913 1.0 1.0 12 Q8TAA9 1 +Abnormal shoulder morphology 0.3716727225812173 0.5567712510209517 0.5776837285415741 1.0 1.0 28 P55011,Q04656,Q9Y619,Q7LGA3,Q9Y4P3,Q96PU5 6 +Abnormal sputum 0.4781583427941424 0.5546304142298231 0.5791474813933073 1.0 1.0 6 Q9NZ08,P01889 2 +Broad nasal tip 0.3599980236563004 0.5533457902192139 0.5800266516273267 1.0 1.0 56 P10644,P98164,Q9UHX1,Q15042,P10586,P16278,Q9Y487,O95831,Q86UE8,Q7LGA3 10 +Attenuation of retinal blood vessels 0.4651516315433928 0.5527492841368786 0.5804351007198658 1.0 1.0 7 P04439 1 +Prolonged bleeding following procedure 0.698131760078658 0.5524860421150923 0.5806153948094206 1.0 1.0 2 P49257 1 +Increased hepatocellular lipid droplets 0.6320572546377599 0.5507291581671461 0.5818193532655074 1.0 1.0 3 Q9Y6B6 1 +Bell shaped thorax 0.6320165232728094 0.5505888539938157 0.581915551279099 1.0 1.0 3 Q8WVQ1 1 +Arterial stenosis 0.3704550268142434 0.5475946137743596 0.5839702886437919 1.0 1.0 18 P04114,Q04656,P01130,P01889 4 +Abnormal brain lactate level by mrs 0.4042040463974019 0.5456799358032015 0.5852859662625858 1.0 1.0 13 O43819,O00429,P00403,Q15526,P03886,O95169,P03915 7 +Recurrent bacterial skin infections 0.630466211536327 0.5452567716071735 0.5855769307006311 1.0 1.0 3 P53634 1 +Oral ulcer 0.4475097724346776 0.5421454397523044 0.5877183178094683 1.0 1.0 8 Q9NZ08 1 +Central hypothyroidism 0.4127903181799967 0.5415357067847231 0.5881383931747188 1.0 1.0 11 P35222,Q8N3U4,P16870,Q99496,O14654 5 +Undetectable visual evoked potentials 0.6948541461815841 0.5413482266459724 0.5882675854573745 1.0 1.0 2 Q8TC12 1 +Arteriovenous malformation 0.4624178558200351 0.5396834136991213 0.5894153804023348 1.0 1.0 7 P08236,Q9BXW9 2 +Insulin resistance 0.391488287992551 0.5396803739028773 0.5894174771152969 1.0 1.0 15 O75844,Q9Y6M1,O76024,O75431,P18031,P31751 6 +Hyperkalemia 0.5414875945885916 0.5392720343126791 0.5896991624214407 1.0 1.0 4 Q13423 1 +Amblyopia 0.3972937206908496 0.5375097862096997 0.590915526924626 1.0 1.0 14 P53701,Q9UHX1 2 +Emphysema 0.4308493052669291 0.5357512651741762 0.5921304679418455 1.0 1.0 9 P06280 1 +Abnormality of the diencephalon 0.370079816368142 0.5356353487045434 0.5922105934958726 1.0 1.0 30 Q8N3U4,P19022,Q9UPT5,O43819,O43924,Q99496,Q9Y5P6,Q8WWQ0,P11166,Q15526,O75306,Q9Y4P3,Q9H9S5,O95169 14 +Punctate cataract 0.6271226362641336 0.5338118227164973 0.5934717332448403 1.0 1.0 3 Q9H6K4 1 +Diastasis recti 0.6270363313128765 0.5335174082928714 0.593675463749074 1.0 1.0 3 Q96JJ3 1 +Symptomatic seizures 0.4457165141318089 0.5331952581588555 0.593898423629474 1.0 1.0 8 Q13423 1 +Spastic paraplegia 0.3704483286919035 0.5326219204777908 0.5942953249629959 1.0 1.0 42 P04062,P56192,Q7KZN9,O95831,Q9P0J0,P11166,Q9Y619,O60313,O00754,Q15526,P07942,O00400 12 +Peptic ulcer 0.4146669127932143 0.5313916572908273 0.5951474015290472 1.0 1.0 10 P04062,O76024 2 +Prominent occiput 0.3901692532837162 0.5313480865948306 0.5951775886836952 1.0 1.0 15 P14543,Q04656 2 +Decreased number of peripheral myelinated nerve fibers 0.401673397950787 0.5306334854983411 0.5956727865955758 1.0 1.0 13 P39210,P07196,O15269 3 +Female sexual dysfunction 0.5049834994297494 0.5263041262842265 0.5986769165356574 1.0 1.0 5 O00592 1 +Middle age onset 0.4127548608148619 0.5209393077306386 0.6024090516283234 1.0 1.0 10 P07602 1 +Choanal stenosis 0.5363946129825653 0.5201023819800363 0.602992218286575 1.0 1.0 4 P16435 1 +Abnormal ureter morphology 0.3635784735755267 0.5193068166372302 0.6035468005643967 1.0 1.0 24 O75844,O76024,Q8TAA9,Q7LGA3,P23786 5 +Chromosomal breakage induced by crosslinking agents 0.6225649553589855 0.5183346705924097 0.6042247869324493 1.0 1.0 3 P13073 1 +Short nail 0.5024380129506697 0.5157744257777357 0.6060119663434385 1.0 1.0 5 O75844 1 +Abnormal foot bone ossification 0.6217416134510825 0.5155542887883541 0.6061657433913765 1.0 1.0 3 Q8WVQ1 1 +Connective tissue nevi 0.6216565330343522 0.5152672518861576 0.6063662796959044 1.0 1.0 3 Q6NUK1 1 +Aganglionic megacolon 0.3579303396126264 0.5101406984920297 0.6099528942536483 1.0 1.0 20 Q9BXW9,Q96EK5,P21964,P54198,P42892,Q04656,Q92889 7 +Difficulty running 0.3980862980180609 0.5093862569204204 0.6104815075012482 1.0 1.0 13 Q9BPX6,Q9Y5P6,Q9Y6X9,P07196,Q9H9S5 5 +Functional motor deficit 0.3284692890204395 0.5004371064231746 0.6167673310610686 1.0 1.0 132 Q13501,P07602,P53701,Q15526,Q9H9S5,P04062,Q99720,Q07021,Q9HC21,Q9BPX6,P03886,Q13510,P03915,P10644,O75787,Q7RTS9,P00403,Q9H2C2,P23786,Q9Y2R0,Q9H2D1,Q9NWM8,P46020,Q9NZJ7,P12235,P35637,Q9Y285,O43292,O14773 29 +Aplasia hypoplasia affecting the eye 0.3014843517368431 0.4986469210931233 0.618028143853341 1.0 1.0 97 O75569,Q92889,Q86YV9,Q99519,P53701,Q7LGA3,Q9NP72,Q9H9S5,Q9NVI7,Q9P273,Q9Y5P6,P08069,Q8WWQ0,P18074,Q9BXW9,P98164,Q9UHX1,Q15042,Q5SZK8,Q6NUK1,O43505,Q9BZK7,P21964,Q15555,P11166,P07196,O95202,Q9Y4P3,Q96CW1 29 +Difficulty walking 0.3301551957241284 0.49834377525178 0.6182417585379043 1.0 1.0 69 Q13501,Q9Y6X9,Q92889,P07602,Q15526,Q9H9S5,Q15067,Q99720,Q9HC21,Q9Y5P6,Q9BPX6,Q13510,Q9BUK6,Q7RTS9,Q9H2C2,Q9NZJ7,P35637,O00429,O43292,O14773 20 +Periventricular heterotopia 0.4086004796777664 0.4983173051809364 0.6182604124647058 1.0 1.0 10 Q6NUK1,Q96PU5 2 +Dystrophic toenail 0.4968091982668271 0.4926506642820457 0.6222594429634891 1.0 1.0 5 O75844 1 +Hypoplastic labia majora 0.3998074576572283 0.4918012749290513 0.6228598351615249 1.0 1.0 12 P16435,Q9Y619,Q6NUK1 3 +Abnormal labia majora morphology 0.3998074576572283 0.4918012749290513 0.6228598351615249 1.0 1.0 12 P16435,Q9Y619,Q6NUK1 3 +Primary adrenal insufficiency 0.3838319753240139 0.4915123221053283 0.6230641391197131 1.0 1.0 15 P40855,Q13423 2 +Abnormal aldolase level 0.6144657037153058 0.4911975275481838 0.623286747489812 1.0 1.0 3 Q9H9S5 1 +Demyelinating peripheral neuropathy 0.3698060599585498 0.4890567337172312 0.6248015315730222 1.0 1.0 17 O00462,Q92889,P07196,P03886,P03915 5 +Abnormal aortic arch morphology 0.4032327643986034 0.48806066089568 0.6255068745554766 1.0 1.0 11 Q9UHX1 1 +Hepatic failure 0.3647678975412106 0.4872820344250902 0.6260584774474083 1.0 1.0 43 P04062,O15118,P40855,P01889,P39210,P38571,P09622,Q9Y619,Q96J02,P23786,P03886,Q13510 12 +Abnormal brainstem morphology 0.2924571773202461 0.4862863540998774 0.6267641529031529 1.0 1.0 87 Q9UPT5,Q9Y6M9,Q96CU9,Q15526,Q9H9S5,Q9BTW9,P98155,Q9Y5P6,O95831,Q9NPL8,Q9Y320,Q9UID3,P07942,P03886,O96000,Q86Y39,O43676,O43505,O95169,Q96EK5,O43819,O00429,Q9UNW1,O60313,Q5KU26,O60508 26 +Cervical spinal canal stenosis 0.6774827925270348 0.4837920314513764 0.628533470880192 1.0 1.0 2 Q9NSE4 1 +Poor eye contact 0.3651321572054861 0.4829158853975439 0.6291554620545099 1.0 1.0 35 Q9UHX1,O96000,Q9Y6M9,Q10471,Q9P0J0,Q86Y39,O43676,Q5KU26,Q5XKP0,P03886 10 +Horizontal eyebrow 0.4943453706900857 0.4826013740492587 0.6293788033011878 1.0 1.0 5 P11233,Q16531,P00533 3 +Aplasia hypoplasia of the optic nerve 0.3609896275862912 0.4815377674244368 0.6301343442367773 1.0 1.0 18 Q9NVI7,Q9UHX1,Q9Y5P6,Q8WWQ0,P07196,Q9H9S5 6 +Skin plaque 0.4620485075211835 0.4812851144613572 0.6303138750791994 1.0 1.0 6 Q06136,P16615 2 +Hypochromic anemia 0.4019662984800837 0.4810263442974673 0.6304977753302716 1.0 1.0 11 Q96JJ3 1 +Hypokalemia 0.4498713345243542 0.4803517964856854 0.6309772639687348 1.0 1.0 7 P0DP25 1 +Hyperkinetic movements 0.4015008585733586 0.4784444115923006 0.6323339302105864 1.0 1.0 11 P07602,Q92581 2 +Abnormal urinary electrolyte concentration 0.3752293814892418 0.4780892009311786 0.6325867179341909 1.0 1.0 16 P05023,Q9Y4P3,Q13423 3 +Abnormal bleeding 0.3091485946221591 0.4732510373882079 0.6360340895046166 1.0 1.0 109 O75844,Q16625,P51798,Q99519,P05067,Q96PU5,P04062,Q9NZ08,P10644,Q9UHX1,Q96JJ3,P01889,Q04656,P11117,Q14108,P23786,Q14739,P21964,Q9Y487,P38435,P15529,O76024,Q4KMQ2 23 +Bundle branch block 0.3908297946089975 0.466720924929486 0.6406995568794311 1.0 1.0 13 Q9H490,P06280,P36543 3 +Inappropriate crying 0.4468690507451055 0.4663227935855692 0.6409844657225185 1.0 1.0 7 P07602 1 +Chorea 0.2909888909342312 0.4656490543790963 0.641466724230499 1.0 1.0 82 Q96N66,P55011,Q9BPX6,P35637,P03915,Q99720,Q04656,Q9P0J0,P11166,P07602,Q01105,Q15526,P17900,Q9NZ01,Q5XKP0,P03886,O95169,Q9NZJ7 18 +Cholestasis 0.3270655514710136 0.4631796551257218 0.6432355979111577 1.0 1.0 69 P10644,Q14739,O15118,P61916,Q16625,P40855,P39210,O75787,P38571,Q04656,Q5HYI8,Q15904,P11166,Q13510 14 +Malnutrition 0.4461828187930367 0.4631260405263541 0.6432740254659235 1.0 1.0 7 Q9Y6B6 1 +Abnormal urine protein level 0.3412698239491445 0.4620066045041919 0.6440765842397811 1.0 1.0 62 P04062,P98164,P09601,P06280,Q8NFH4,O95470,P15529,Q99519,Q14108,Q15526,Q96J84,Q9Y4P3,P03886,P03915 14 +Central hypoventilation 0.4308685428951684 0.4599491915114048 0.6455526902733799 1.0 1.0 8 O43819,O95169,Q15526 3 +Abnormal fear anxiety related behavior 0.3117443756632724 0.4557531785460837 0.6485674767103804 1.0 1.0 114 Q13501,P55011,O00592,Q7LGA3,P19022,P06280,Q68CQ7,O00754,Q86UE8,P03886,P03915,P10644,P55795,P00403,P17900,Q6DKK2,P12235,P21964,P35637,O75503,Q15165,O76024,P11166,Q9Y4P3 24 +Paraplegia paraparesis 0.3240616474748958 0.4555582417569651 0.6487076771248192 1.0 1.0 70 Q13501,Q7KZN9,Q96CU9,Q9P0J0,Q15526,P04062,P56192,O95831,Q9Y619,O00754,P07942,Q13510,O75787,Q6DKK2,P35637,P11166,O60313,Q5XKP0,O00400 19 +Pectus carinatum 0.3619643791457471 0.4553013112513072 0.6488924830362284 1.0 1.0 37 Q9NVI7,P55011,P16278,P55795,Q04656,P08236,Q99519,Q9Y619,O00754 9 +Abnormality of somatosensory evoked potentials 0.603189249990602 0.4542437583429623 0.6496533910859901 1.0 1.0 3 Q9NQZ5 1 +Limb girdle muscle atrophy 0.3886171944811492 0.4538035537247924 0.649970225587704 1.0 1.0 13 O14979,P50402,Q9H9S5 3 +Abnormal blood monovalent inorganic cation concentration 0.3499302759262803 0.4521705571093156 0.6511461171828885 1.0 1.0 20 Q9BV10,P11166,Q13423,P0DP25 4 +Head titubation 0.4550912961104206 0.4501896244652029 0.652573716945229 1.0 1.0 6 Q99720 1 +Abnormality of female external genitalia 0.3612344475513783 0.4493703853202531 0.6531644910011098 1.0 1.0 37 Q15392,P10644,P51809,O75381,P40855,Q15042,Q5SZK8,Q6NUK1,O95155,P50542,Q9Y619,P53701,P16435,Q9UBM7,Q9UNW1,Q9NP72,O75419 17 +Generalized onset motor seizure 0.3539074970406217 0.4480182201484552 0.6541400471480432 1.0 1.0 52 P04062,Q96N66,Q8NHS3,P16278,Q99519,Q9Y619,P07602,Q01105,Q92581,P11166,P03886,Q13510,Q9NZJ7 13 +Accelerated skeletal maturation 0.3990199125395203 0.4466548979226685 0.6551242513520064 1.0 1.0 10 P10644 1 +Limited elbow extension 0.3872569482246003 0.4458851091629776 0.6556802391281731 1.0 1.0 13 P16435,Q96J02,Q04656,Q7RTS9 4 +Truncus arteriosus 0.398591639456618 0.4443634140688253 0.6567798602358077 1.0 1.0 10 Q9UHX1 1 +Paraplegia 0.3588934500641927 0.4403634927874735 0.6596738615431934 1.0 1.0 44 P04062,P56192,Q7KZN9,O95831,Q9P0J0,P11166,Q9Y619,O60313,O00754,Q15526,P07942,O00400 12 +Wide anterior fontanel 0.3516682659354945 0.4387315341611222 0.6608560749551344 1.0 1.0 23 O75381,P98164,P40855,Q9Y487,Q6NUK1,P42345,P16435,O75419 8 +Craniofacial osteosclerosis 0.5982504007315226 0.4383804745624348 0.6611104981404625 1.0 1.0 3 P51798 1 +Abnormal pulmonary interstitial morphology 0.3559427244690653 0.4364502597520961 0.6625100802760984 1.0 1.0 28 P04062,P56192,P09601,Q14108,Q8IZA0 5 +Hyperactive deep tendon reflexes 0.425820457837496 0.4354376063001686 0.6632448185907522 1.0 1.0 8 P11166,O75787 2 +Abnormal peripheral action potential amplitude 0.3967197974596994 0.4343673548383831 0.6640216997851491 1.0 1.0 10 P39210,Q6DD88,O15269 3 +Aphthous ulcer 0.4395383197622947 0.4323719928970557 0.6654710702987408 1.0 1.0 7 Q9NZ08 1 +Tongue atrophy 0.4813381072333986 0.430337065104229 0.6669504686381573 1.0 1.0 5 P07196,Q9NQT5,Q9Y6X9 3 +Neurogenic bladder 0.450155545445665 0.4283680164703318 0.6683832065144859 1.0 1.0 6 Q8TAA9 1 +Eeg with abnormally slow frequencies 0.3478107447980341 0.4277379528819006 0.6688419149095557 1.0 1.0 21 O75503,Q13501,Q9H2C2 3 +Elevated circulating alanine aminotransferase concentration 0.3922655785474386 0.4276000910358669 0.668942299661087 1.0 1.0 11 Q15904,P10253 2 +Perisylvian polymicrogyria 0.5108667202742637 0.4268757187633198 0.6694698519385465 1.0 1.0 4 Q15042 1 +Abnormality of the coagulation cascade 0.3584850008874517 0.426747543902072 0.6695632172611186 1.0 1.0 39 P10644,Q9BV10,Q9Y487,Q6NUQ1,P38435,P15529,Q9Y619,Q4KMQ2,Q5XKP0 9 +Lack of peer relationships 0.5936618727523146 0.4238264356644087 0.6716923972460735 1.0 1.0 3 P11166 1 +Paraparesis 0.3539851232792927 0.4216633750709421 0.6732707409679819 1.0 1.0 28 P04062,Q13501,O75787,Q9Y619,Q5XKP0,Q13510 6 +Short clavicles 0.3911125381955905 0.4213071419783858 0.6735308156952775 1.0 1.0 11 O75844 1 +Decreased circulating antibody level 0.3572984596988928 0.4208291801081646 0.6738798221445421 1.0 1.0 42 P02786,P09601,Q9BV10,Q15904,O00754,Q96J02 6 +Arnold chiari malformation 0.3478240741045739 0.4190564093125111 0.6751749071159052 1.0 1.0 22 P16435,Q8TAA9,O00754,Q15043,Q9Y4P3,O75419 6 +Abnormal carotid artery morphology 0.3518090697503455 0.4183716263384731 0.6756754282774753 1.0 1.0 18 O75844,Q04656,P04114,P01130,Q9Y4P3 5 +Dolichocephaly 0.3527292856985468 0.4181551060658801 0.6758337169971034 1.0 1.0 27 O75381,Q9BXW9,P40855,Q7RTS9,Q92889,Q96J02,O95202,Q4J6C6 8 +Abnormality of ocular smooth pursuit 0.3436926249851846 0.4172278728239631 0.6765117396311451 1.0 1.0 19 Q9BTW9,Q9UBB4,O14773,O00754,P46977 5 +Bronchitis 0.4474399238543297 0.4164516771537944 0.6770795205103739 1.0 1.0 6 Q03518 1 +Hypoventilation 0.3716511389360828 0.4159985999656611 0.677411027688047 1.0 1.0 15 Q9H9S5,Q15526 2 +Gastric ulcer 0.5911538286219733 0.4159482618701183 0.6774478628860954 1.0 1.0 3 P04062 1 +Abnormal pericardium morphology 0.3932277513035697 0.4158056082719296 0.6775522546868289 1.0 1.0 10 P04062,Q9NZ08,Q14108 3 +Abnormality of temperature regulation 0.3002912577253065 0.4156207152788201 0.6776875658680324 1.0 1.0 103 Q9HC07,P51798,P07602,P15260,Q2TAA5,Q9HC21,P06280,Q9NZ08,P03886,Q13510,P03915,P10644,P01889,P38571,Q04656,P23786,P10253,Q9NZJ7,Q14739,Q8NFH4,Q5XKP0 21 +Chronic infection 0.3898137528835295 0.4142343885066786 0.6787024594724018 1.0 1.0 11 P10644 1 +Eeg with polyspike wave complexes 0.4468044657612721 0.4136727542437612 0.6791137832634715 1.0 1.0 6 Q14108 1 +Microcornea 0.3528939639018525 0.4134422599061479 0.6792826179476688 1.0 1.0 28 Q9P273,Q9BZK7,Q15042,Q15555,Q9NWM8,Q9NP72,O43505,Q9H9S5,P18074 9 +Increased csf lactate 0.3535588834471458 0.4134270799723918 0.6792937376546988 1.0 1.0 48 P13073,P39210,Q9HC21,O96000,Q9Y6M9,Q7KZN9,Q9P0J0,O95831,P00403,Q86Y39,O43676,Q15526,P03886,O95169,P03915 15 +Contractures of the joints of the upper limbs 0.320354243543272 0.412914947001498 0.6796689296172751 1.0 1.0 70 Q15392,O75844,Q9H4L7,Q9Y6X9,Q7LGA3,Q99720,O95155,Q9Y619,Q8IZA0,P18074,O75419,Q15042,P23786,P50402,P35637,P42892,P16435,P48651,Q8WVQ1,P07196 20 +Open mouth 0.3533797523573797 0.4066654418136413 0.6842537254817238 1.0 1.0 30 P10644,Q86XL3,Q92581 3 +Kinetic tremor 0.3549732771215756 0.4042002289707445 0.6860654853820845 1.0 1.0 34 P98155,Q14108,Q9Y287,P07602 4 +Increased connective tissue 0.419152725114464 0.4034072231938119 0.6866486738503801 1.0 1.0 8 O95831,P31751 2 +Abnormal iris pigmentation 0.3495720216711493 0.4031371853377452 0.686847306386636 1.0 1.0 18 P10644,O75381,P40855,O95155,Q86YV9,Q9Y4P3 6 +Difficulty climbing stairs 0.3797506868580661 0.4025229599451996 0.6872991944718532 1.0 1.0 13 P12235 1 +Abnormal shape of the occiput 0.3521352907222921 0.4022232593670242 0.6875197259599899 1.0 1.0 29 P14543,Q96J02,Q04656,O00754 4 +Epidermoid cyst 0.5033562454185225 0.4004650151075719 0.6888140462856556 1.0 1.0 4 P49815 1 +Stomatitis 0.3690669016144721 0.4001831330964431 0.6890216368181203 1.0 1.0 15 P10644,Q9NZ08 2 +Osteopenia 0.3167818078469905 0.3987688371551434 0.690063540898012 1.0 1.0 71 P10644,P04062,O75844,Q9Y487,Q9H490,Q04656,Q9NWM8,P07602,O00754,Q14108,Q13277,P07237,Q9Y4P3,Q9NZJ7 14 +Atypical absence seizure 0.6496230744018525 0.3972152082146029 0.691208768256987 1.0 1.0 2 Q96CW1 1 +Dilation of virchow robin spaces 0.649623074401829 0.3972152082145336 0.691208768257038 1.0 1.0 2 P27635 1 +Skin vesicle 0.3830000160343166 0.3969459361316995 0.6914073288848313 1.0 1.0 12 P16615 1 +Abnormality of the pharynx 0.349116199243567 0.3948985548743642 0.6929177565443045 1.0 1.0 51 P54802,P21964,P01889,Q9BV10,P16278,Q03518,P08236,P15586,Q13277,Q13510 10 +Craniosynostosis 0.3540887767005914 0.3911263788628523 0.6957038231234263 1.0 1.0 40 P21964,Q6NUK1,P51798,Q9NX62,P16435,Q9Y619,O00754,Q86UE8 8 +Exercise induced myoglobinuria 0.4710129077144367 0.3898826175437653 0.6966233480020587 1.0 1.0 5 Q9H9S5 1 +Emotional lability 0.3431424802892342 0.3893770745074297 0.6969972284546637 1.0 1.0 56 P10644,Q92804,Q13501,P35637,Q15165,Q68CQ7,Q7KZN9,Q96CU9,Q9P0J0,P07602,Q15526,Q9NZJ7 12 +Aplasia hypoplasia involving the nose 0.3487046255563399 0.3881517609196602 0.6979037291418382 1.0 1.0 27 Q5KU26,O75844,Q5SZK8 3 +Hypoplasia of the radius 0.3879806478076337 0.3881394624693736 0.6979128298606516 1.0 1.0 10 P10644 1 +Centrally nucleated skeletal muscle fibers 0.4404332129964086 0.3860178214177496 0.6994834702391128 1.0 1.0 6 P22626,Q9Y5L0,P06753,P50570,Q9BPX6 5 +Generalized onset seizure 0.2949379751952527 0.3852831378159575 0.7000276531452032 1.0 1.0 99 Q96N66,P55011,P05023,Q99519,P07602,P04062,Q9NVI7,Q8NHS3,Q9Y619,Q01105,P03886,Q13510,P03915,P16278,Q14108,Q92581,Q9NZJ7,P00374,Q96C86,O75503,P11166,Q9NZ01 22 +Elfin facies 0.4398843901014094 0.3836537621723723 0.7012350871604116 1.0 1.0 6 Q9Y4P3 1 +Hyperventilation 0.4398509120165654 0.3835096506974275 0.7013419160418599 1.0 1.0 6 P11166,P03886 2 +Macular atrophy 0.4282971084274308 0.3812327690992742 0.7030305356217494 1.0 1.0 7 P04439 1 +Limb pain 0.4143985095157568 0.3808281461514877 0.7033307726260363 1.0 1.0 8 Q6DD88,O15269 2 +Disseminated intravascular coagulation 0.3863964792611581 0.3798426343374697 0.704062232396184 1.0 1.0 10 P10644,P15529 2 +Abnormality of the scrotum 0.350949460441643 0.3798267097267016 0.704074054100821 1.0 1.0 46 P51809,P55011,Q9BV10,Q5SZK8,Q15555,Q6NUK1,P16435,Q9Y619,Q7LGA3 9 +Distal peripheral sensory neuropathy 0.4682643081690929 0.3792814139005108 0.704478899976817 1.0 1.0 5 P03886,P03915 2 +Hyperpigmentation of the fundus 0.6433956079973835 0.3789254820925143 0.7047432008413479 1.0 1.0 2 O15484 1 +Odontogenic neoplasm 0.643395607997371 0.3789254820924775 0.7047432008413752 1.0 1.0 2 Q01968 1 +Melena 0.643395607997371 0.3789254820924775 0.7047432008413752 1.0 1.0 2 Q02241 1 +Hypothermia 0.4000948117343962 0.3787151146031017 0.70489942817094 1.0 1.0 9 Q04656,P03886,Q5XKP0 3 +Arthralgia 0.3515506692555052 0.3773737905448685 0.7058958416263237 1.0 1.0 34 P01889,P06280,P04114,Q9NZ08,Q9Y4P3,P01130,Q96HY6,Q13510 8 +Hypoproteinemia 0.6427400852179546 0.3770241966993422 0.70615562319096 1.0 1.0 2 Q9UJS0 1 +Abnormality of lens shape 0.6427400852179543 0.377024196699341 0.7061556231909609 1.0 1.0 2 Q01968 1 +Opisthotonus 0.3425925619442368 0.3728853020975148 0.7092338116142409 1.0 1.0 23 P04062,Q99720,P11117,P07602,Q2TAA5,O60313,Q9NZJ7 7 +Joint stiffness 0.3387222103929126 0.3720668177861074 0.7098431011877329 1.0 1.0 58 P54802,O75844,P01889,Q15042,P16278,P08236,O76024,Q8TAA9,P16435,O00754,P51648,P15586 12 +Abnormal epidermal morphology 0.3397455111770002 0.3700959925011463 0.7113109679792187 1.0 1.0 21 O75844,P01889,P16615,Q07954,Q14574 5 +Tetraparesis 0.3498759887598651 0.3643074754054393 0.7156284183100596 1.0 1.0 34 P17900,Q13501,P07602 3 +Joint hypermobility 0.2902282339965979 0.3642420603712361 0.7156772613898863 1.0 1.0 95 P55011,Q7LGA3,P07237,Q96PU5,Q9Y619,Q01105,Q86UE8,Q9H490,Q9UHX1,Q15042,Q04656,Q15904,Q92581,Q9NWM8,P21964,Q9Y487,Q9Y285,Q8WVQ1,Q9Y4P3 19 +Abnormality of the intrinsic pathway 0.3768655964166366 0.3630479070063628 0.7165690975963794 1.0 1.0 12 P38435,Q9BV10,Q9Y487 3 +Decreased adipose tissue 0.3570240793375385 0.3625122343493288 0.7169692827032146 1.0 1.0 16 O75844,Q6NUK1,P08069,Q92889,P18074,P36543 6 +Genetic anticipation 0.6374959029826406 0.3619812721843168 0.7173660254383876 1.0 1.0 2 Q9UBB4 1 +Low back pain 0.6374959029826218 0.3619812721842639 0.7173660254384271 1.0 1.0 2 Q8WVX9 1 +Tube feeding 0.3389384629875054 0.3610620679961122 0.7180530485552539 1.0 1.0 57 Q96N66,P55011,Q9UHX1,P35637,Q9BV10,Q99720,Q9NZ01,P07602,Q01105,Q96J02,Q9H490,Q9NZJ7 12 +Hyporeflexia 0.3047891428508612 0.3599354446830167 0.718895409960258 1.0 1.0 114 Q13501,P39210,P05023,O00592,P07602,Q9H9S5,P54802,P04062,Q99720,Q6DD88,Q9HC21,O95831,Q16637,P03886,P03915,O14979,O75787,Q04656,Q9H2C2,O43505,Q9NZJ7,P12235,P35637,O15269,P07196 25 +Motor axonal neuropathy 0.3624199712990191 0.3598811811993375 0.718935990683587 1.0 1.0 15 Q6DD88,Q9Y6X9,O95831,O60313,O15269 5 +Abnormal cartilage morphology 0.3720415395530465 0.358638596839935 0.7198654689342772 1.0 1.0 13 Q7LGA3 1 +Aplasia hypoplasia involving the metacarpal bones 0.342648073379025 0.3575092782221968 0.7207105815278734 1.0 1.0 25 P10644,Q14739,Q9BXW9,Q9NX62,P16435,Q8WVQ1 6 +Episodic hypertension 0.6358570960340804 0.3573420731881996 0.7208357365188887 1.0 1.0 2 P21912 1 +Loss of ability to walk 0.371510162416001 0.3556402229008988 0.7221100169304155 1.0 1.0 13 Q99519 1 +Retinal hemorrhage 0.4330012303456906 0.3542620635347972 0.7231424954458572 1.0 1.0 6 Q9Y487 1 +Abnormality of corneal size 0.3487639688655872 0.3473989013837971 0.7282916585790962 1.0 1.0 39 Q9P273,Q9BZK7,Q15042,O95202,Q15555,P36404,Q9Y5P6,Q9Y4P3,Q9NWM8,Q9NP72,O43505,Q9H9S5,P18074 13 +Spina bifida occulta 0.354539579435905 0.3470656401963118 0.7285420061028751 1.0 1.0 16 Q8TAA9,Q9UHX1 2 +Mottled pigmentation 0.568371610044579 0.3470355701908943 0.728564596270781 1.0 1.0 3 O75844 1 +Breast aplasia 0.5674975125318077 0.3444916502118248 0.7304765743755641 1.0 1.0 3 Q9Y619 1 +Abnormal delivery 0.3356892274633705 0.3414784396767567 0.7327434331566653 1.0 1.0 21 O75844,Q9Y619,Q9Y487 3 +Difficulty standing 0.429728882304961 0.3404629043843399 0.7335079539655442 1.0 1.0 6 Q7RTS9 1 +Upper extremity joint dislocation 0.3341726179200474 0.3404088015622454 0.7335486913705034 1.0 1.0 20 P10644,Q9Y619,Q8WVQ1 3 +Abnormality of blood circulation 0.3018703756822095 0.3396065559717383 0.7341528403343403 1.0 1.0 75 P10644,P04062,O75844,Q14739,P21964,Q9UHX1,P01889,Q9Y487,Q04656,P23786,P38435,P15529,O76024,Q9NZ08,Q13277,P05067 16 +Cystic liver disease 0.4575476690122526 0.338674322053328 0.7348550866821237 1.0 1.0 5 P14314,P49815 2 +Abnormal csf metabolite level 0.3389455972609073 0.3378947064338917 0.7354425368496949 1.0 1.0 55 P39210,Q9HC21,O96000,Q9Y6M9,Q7KZN9,Q9P0J0,O95831,P00403,Q86Y39,O43676,P11166,Q15526,P03886,P13073,P03915 15 +Thick eyebrow 0.34631143466386 0.3359909397233062 0.7368776987758667 1.0 1.0 45 Q9UHX1,P04066,O95831,P08236,O00754,Q92581,P15586 7 +Abnormal blood transition element cation concentration 0.3715502478278801 0.3340402308083034 0.738349200761488 1.0 1.0 12 Q10567,Q9Y487,O43819,Q6PGP7,Q15904,P28288 6 +Multiple prenatal fractures 0.4275898373326188 0.3315061239118034 0.7402622160484589 1.0 1.0 6 Q14739,Q32P28 2 +Dysphagia 0.31675572100693 0.3304196943816554 0.7410828624448751 1.0 1.0 133 Q13501,P61916,P55011,Q99519,P07602,Q15526,P05067,P04062,O15118,Q99720,Q01105,Q8IZA0,P15586,P03886,Q13510,P03915,Q9UHX1,P01889,Q04656,Q14108,Q92581,O95169,Q9NZJ7,Q14739,P12235,O76024,O60313 27 +Proximal upper limb amyotrophy 0.4166847817352339 0.3297350098912835 0.7416001977558926 1.0 1.0 7 O14979,P50402,Q9Y6X9 3 +Abnormality of the musculature of the upper arm 0.4166847817352339 0.3297350098912835 0.7416001977558926 1.0 1.0 7 O14979,P50402,Q9Y6X9 3 +Abnormal circulating albumin concentration 0.3443854575170273 0.3292424402412522 0.7419724467987656 1.0 1.0 32 Q9BV10,Q9BT22,Q8NFH4,O95470,P15260,Q9Y6B6,Q5XKP0 7 +Hyperpituitarism 0.3311051415719311 0.3291256867381097 0.7420606896312867 1.0 1.0 19 P10644,P51809 2 +Abnormality of the vertebral endplates 0.4162770395844045 0.3279536730993327 0.7429466905990689 1.0 1.0 7 P51798 1 +Abnormal muscle glycogen content 0.561389295147133 0.3269326289757848 0.7437188416040743 1.0 1.0 3 Q9BUK6 1 +Vertebral compression fracture 0.3509044068356443 0.3246286117076088 0.7454621700414599 1.0 1.0 16 P04062,Q96HY6,Q14108 3 +Abnormal blood phosphate concentration 0.4154960315373412 0.3245469652404996 0.7455239715998403 1.0 1.0 7 P10644 1 +High forehead 0.2857503477159111 0.3243711761056924 0.7456570391614128 1.0 1.0 93 Q14739,P40855,P55011,O95202,Q04656,P23786,Q9NX62,Q10471,Q15904,Q99519,Q2TAA5,Q9H2C2,Q7LGA3,Q9H490,Q9Y4P3 15 +Papilledema 0.3304040703108014 0.3242952633681925 0.7457145053711458 1.0 1.0 19 Q7LGA3,P04062 2 +Abnormal ciliary body morphology 0.560327868852463 0.3239208286917087 0.7459979744331571 1.0 1.0 3 P11047,Q99496 2 +Abnormality of the carpal bones 0.3507877723797216 0.3239120551912581 0.7460046169011665 1.0 1.0 16 P16435,Q04656,Q8WVQ1 3 +Cavernous hemangioma 0.4804854050508288 0.3233576313339236 0.746424412683153 1.0 1.0 4 P50570,Q02750,P21912 3 +Arthropathy 0.424550801622337 0.3188695494050154 0.7498254359555412 1.0 1.0 6 O15269 1 +Aplasia hypoplasia of the scapulae 0.4519937988318645 0.318111367553237 0.7504004611214448 1.0 1.0 5 P16435 1 +Neck flexor weakness 0.5574838531381807 0.3159094590325244 0.7520712320575329 1.0 1.0 3 Q99720 1 +Down sloping shoulders 0.3316169281887489 0.3130284075535965 0.7542590798229001 1.0 1.0 21 Q7LGA3,Q04656,Q9Y4P3 3 +Hepatic cysts 0.5560162818993988 0.3118090662834665 0.7551856334331561 1.0 1.0 3 P49815 1 +Reticulocytosis 0.3673798947384949 0.311537852028828 0.7553917717919676 1.0 1.0 12 P11166 1 +Impaired tandem gait 0.3585754981399701 0.3076252246865659 0.7583675238779564 1.0 1.0 14 Q7LGA3,O75787 2 +Abnormality of adrenal physiology 0.3425230069761344 0.3074526150011207 0.7584988851651555 1.0 1.0 34 P10644,P51809,P40855,Q13423,P38571,P16435 6 +Calcific stippling 0.5544262295082014 0.3073925559349873 0.758544593599404 1.0 1.0 3 P50542,P51659 2 +Abnormal pleura morphology 0.3356273843709695 0.3069578554874477 0.7588754510117828 1.0 1.0 25 Q14739,P01889,Q6NUK1,P15529,P08236,Q9NZ08 6 +Impaired vibratory sensation 0.3320620150511248 0.306904814361706 0.7589158244781098 1.0 1.0 22 Q9Y6B6,O14773,Q9Y619,P07196 4 +Aplasia hypoplasia of the humerus 0.3694625152168167 0.305857568636878 0.7597130939793546 1.0 1.0 11 Q04656 1 +Tarsal synostosis 0.4744473388256393 0.3039129822449181 0.7611941869240171 1.0 1.0 4 Q04656 1 +Synostosis involving bones of the lower limbs 0.4744473388256393 0.3039129822449181 0.7611941869240171 1.0 1.0 4 Q04656 1 +Joint laxity 0.2988144771574101 0.3021855509650525 0.7625106183378025 1.0 1.0 75 Q9HC07,Q96A33,Q8WVM7,Q9Y5P6,Q8WWQ0,Q9Y619,O00754,O75419,Q9UHX1,P16278,Q9BUK6,P55795,Q04656,Q16531,Q9BZK7,Q96HY6,Q96C86,Q9Y487,Q32P28,Q8WVQ1,Q9Y4P3,P36543 22 +Incomitant strabismus 0.3617059642689012 0.3009942046443374 0.763418913754927 1.0 1.0 13 Q7LGA3,O60313 2 +Asymmetric growth 0.3840945704561357 0.3007182174995196 0.7636293758787256 1.0 1.0 9 Q15555 1 +Abnormality of earlobe 0.335541671885044 0.2988416515566278 0.7650608689275047 1.0 1.0 26 Q15392,P21964,P10586,P16435,P53701,Q7LGA3,Q9BZK7 7 +Abnormal bronchus morphology 0.3307972353939641 0.298087558937623 0.7656363367203516 1.0 1.0 22 Q13277,Q03518,Q96HY6,P00533 4 +Severe muscular hypotonia 0.3331367240010849 0.2972285481111111 0.766292027946605 1.0 1.0 24 O75381,P40855,O95831,P53007,Q01105,Q9NWM8,O43505,Q9H9S5 8 +Nail dysplasia 0.3388024944991996 0.2970704671803476 0.7664127108959489 1.0 1.0 30 P16615,P42892,Q9Y619,P10321 4 +Abnormal ossification involving the femoral head and neck 0.4453628306839526 0.2940201573041707 0.7687425004933282 1.0 1.0 5 Q14739,Q9NUQ7,Q7RTS9 3 +Cyanosis 0.3397308309552708 0.2932609863445076 0.7693226716907937 1.0 1.0 17 O75844,P04066 2 +Weight loss 0.2927827090425094 0.2924091630593743 0.7699738031282786 1.0 1.0 77 P10644,P04062,O75844,Q9BXW9,P42892,Q13423,P01889,P38571,Q99720,Q04656,Q06136,Q01844,Q5HYI8,Q9NZ08,P07602,P15260,Q92581,Q9NZJ7 18 +Brain imaging abnormality 0.3416947936353046 0.2909158232503568 0.7711156992570194 1.0 1.0 42 Q13501,Q9NZJ7,Q9BV10,Q9BT22,O00429,P35610,P00403,P11166,P07602,Q15526,P03886,Q9BZK7,O95169,P03915 14 +Dental malocclusion 0.3333722245356024 0.2909053796748262 0.7711236867837474 1.0 1.0 25 P10644,Q5SZK8,P51798 3 +Dilatation of the cerebral artery 0.3689451232626382 0.2903865399852665 0.7715205398302589 1.0 1.0 10 P10644,P10253 2 +Nonketotic hypoglycemia 0.4699260958483738 0.2896222789300434 0.7721052210483892 1.0 1.0 4 P31751 1 +Type ii diabetes mellitus 0.340320280750895 0.2873741414247627 0.7738258586894067 1.0 1.0 35 P16870,Q15555,O76024,Q9Y4P3,P03886,P31751,P03915 7 +Eyelid myoclonus 0.3680746326460969 0.286026921746552 0.7748575019728079 1.0 1.0 10 Q01105,Q13510 2 +Decreased circulating cortisol level 0.3680019018441062 0.2856631481918191 0.775136132470202 1.0 1.0 10 Q13423 1 +Periauricular skin pits 0.3650762667493752 0.2831875963638229 0.77703303602441 1.0 1.0 11 Q07954 1 +Restless legs 0.467573965921103 0.2822814245435036 0.7777277277239687 1.0 1.0 4 O00592 1 +Biventricular hypertrophy 0.5449908840778188 0.2817543622681172 0.7781318672992941 1.0 1.0 3 Q9BV10 1 +Abnormality of the hallux 0.3363500031034425 0.2792363097123059 0.7800634802789688 1.0 1.0 51 P10644,P04062,P55011,Q9UHX1,Q8WVQ1,Q7LGA3,Q96J02,O95202,Q9Y4P3 9 +Esodeviation 0.3400273454762364 0.2784650288562611 0.7806554067121416 1.0 1.0 38 Q9NVI7,P04062,Q9NSE4,O60762,Q9P273,P62070,Q9UHX1,P00387,O43924,Q9H553,P53007,P50542,O43175,Q16531,Q5KU26,P18074 16 +Emg impaired neuromuscular transmission 0.4034396145283764 0.2728933898919156 0.7849351678458065 1.0 1.0 7 P53007,O60313,Q9Y5P6 3 +Restlessness 0.3389987585261374 0.2716798168612155 0.7858682215860362 1.0 1.0 44 P10644,P04062,Q13501,P35637,P42892,O96008,Q15165,Q68CQ7,P35610,P08069,O00592,Q92673,Q92804,P05067 14 +Dilated cardiomyopathy 0.338524226715751 0.2684441451531819 0.7883574630976642 1.0 1.0 37 P42167,P12235,P16278,P00403,Q14126,P53701,Q15526,P23786,P03886,Q9H9S5,P03915 11 +Dysgenesis of the cerebellar vermis 0.6014421501147228 0.2670990988108752 0.7893928614398149 1.0 1.0 2 Q10713 1 +Abnormality of fontanelles 0.3375499427863508 0.2647767374830491 0.7911814582940566 1.0 1.0 46 O75844,O75381,P40855,P98164,Q9Y487,P36543,Q04656,Q9BT22,Q6NUK1,P42345,P16435,Q9Y619,P48651,O75419 14 +Gastrointestinal hemorrhage 0.3357405319163775 0.2642592664608683 0.7915801455453071 1.0 1.0 32 Q14739,P21964,P01889,Q9UHX1,Q04656,Q9NZ08 6 +Pain 0.3441630174838953 0.2635689721583388 0.7921120699217843 1.0 1.0 181 O75844,Q13501,Q70HW3,P51798,P04114,P07602,Q15043,Q9H9S5,P04062,P19022,Q6DD88,P06280,Q68CQ7,Q5HYI8,Q9NZ08,Q8TAA9,P01130,Q13510,P10644,Q13423,P01889,Q04656,Q15800,Q01844,P07686,Q14108,P23786,Q96HY6,P46020,Q9NZJ7,P50402,Q14739,P12235,P42892,P21964,P35637,Q15165,Q8NFH4,Q07954,P15529,O60313,O15269,Q92804,Q9Y4P3 44 +Large for gestational age 0.3761608868155697 0.2632444185819041 0.7923621966561258 1.0 1.0 9 P31751 1 +Adult onset 0.3200865068659675 0.2602693490894892 0.7946560139452137 1.0 1.0 63 Q9UJV9,Q8IV08,P18031,P07602,Q9NQZ5,P43304,P04062,O15118,P14314,Q07021,P42345,Q9Y6M1,Q16637,O14979,P49815,Q9H0U3,Q9NZJ7,Q86U42,P12235,P38435,O76024,P31751 22 +Abnormal peripheral nervous system morphology 0.3269725348130117 0.2601735741710593 0.7947298872760733 1.0 1.0 155 Q13501,P39210,P51798,Q8IV08,Q99519,P07602,Q15526,Q15043,Q9H9S5,Q9NVI7,P56192,P40855,Q99720,Q6DD88,Q9HC21,O95831,Q16637,Q9Y619,Q9BPX6,P03886,Q13510,P03915,P10644,Q9UHX1,Q04656,P00403,Q6DKK2,Q9NZJ7,P12235,P35637,Q9BV10,Q07954,O76024,P48651,O60313,O15269,P07196 37 +Tetraplegia tetraparesis 0.3372195157750679 0.2591141580084131 0.7955471612504117 1.0 1.0 45 Q13501,Q13423,Q7RTS9,Q9UBX3,O95831,P07602,P17900,Q9NZJ7 8 +Flat nasal alae 0.459804704324786 0.2585038814436678 0.7960180537445747 1.0 1.0 4 Q92889,P18074 2 +Progressive 0.2865269701275217 0.2581586877967597 0.7962844398209294 1.0 1.0 100 Q13501,P39210,Q9Y6M9,O95470,Q15043,P54802,P04062,P56192,Q99720,O95831,Q16637,P15586,P07942,Q13510,Q9NR28,P27544,P12235,O60313,Q5XKP0,O00400 20 +Abnormal atrioventricular conduction 0.3569527333195156 0.2563648196176068 0.7976691501919733 1.0 1.0 12 P06280,P0DP25 2 +Aplasia hypoplasia of the breasts 0.3991854502713169 0.2551128152361195 0.7986359664511331 1.0 1.0 7 Q9Y619,O75419 2 +Retinal telangiectasia 0.4085465598472947 0.2541689795013123 0.7993650145875681 1.0 1.0 6 P03886 1 +Abnormality of cranial sutures 0.2757218687265657 0.2526177584480799 0.8005636057681174 1.0 1.0 87 O75844,P21964,P40855,Q9Y487,Q04656,P51798,Q9NX62,Q6NUK1,O95831,P16435,Q9Y619,O00754,Q86UE8,P36543 14 +Insomnia 0.3440210203244652 0.2516563547955893 0.8013066952110128 1.0 1.0 15 O00592,Q10471 2 +Scapular winging 0.3265841796074092 0.2513883189411798 0.8015138979352687 1.0 1.0 24 Q13501,Q9Y487,O00429,Q9Y5P6,Q9H553,O60313,P07196,P50402 8 +Excessive wrinkled skin 0.3609930296809239 0.2509662620444614 0.8018401935473682 1.0 1.0 10 P36543,Q9Y487 2 +Visual field defect 0.3365443287213655 0.2498120100423919 0.8027327314953565 1.0 1.0 43 O75381,P40855,P01889,Q8TC12,Q8NHS3,P04439,Q15555,P00403,Q9Y287,Q9H061,O60313,Q9H6K4,P03886,P03915 14 +Coloboma 0.3355813289631064 0.2481394658198999 0.8040265009723582 1.0 1.0 46 Q96EK5,Q9P273,P98164,Q9UHX1,Q15042,O43924,O60826,Q9Y5P6,P78318,Q9UBM7,P53701,O95202,Q9NP72,O43505,Q9H9S5 15 +Abnormality of the upper arm 0.324726686001438 0.2471899895658469 0.8047611921353237 1.0 1.0 23 O14979,Q9BV10,Q04656,Q7RTS9,P16435,P50402 6 +Broad based gait 0.3246813274041081 0.2468787911362678 0.8050020305895969 1.0 1.0 23 P98155,O14773 2 +Tremor by anatomical site 0.3246418565564091 0.2466080241063291 0.8052115939799644 1.0 1.0 23 P56192,P35637,P04350,Q99720,Q16637,P07196 6 +Myoclonic spasms 0.4063012799474835 0.2453577815987008 0.8061794154219482 1.0 1.0 6 Q6PJG6,Q99496,P31749,Q12824,Q10713 5 +Gastroesophageal reflux 0.3023427274372716 0.24420486949696 0.8070721559080636 1.0 1.0 122 P55011,P07602,Q96J02,Q96A33,Q96PU5,Q6DD88,Q9Y619,Q01105,Q8IZA0,Q9UHX1,Q04656,Q6NUK1,Q92581,Q9H2C2,Q9NZJ7,Q14739,P12235,P21964,Q9BV10,P16435,O15269,O95202,Q9Y4P3 23 +Polycystic liver disease 0.5304240408184067 0.2441581843616644 0.8071083111574826 1.0 1.0 3 P14314 1 +Respiratory distress 0.3293118029747139 0.2385025380057303 0.8114913470996741 1.0 1.0 54 P53701,P07602,Q15526,P04062,O95831,Q9Y619,P03886,Q13510,P03915,O75419,Q9UHX1,P04350,P49815,P23786,P10253,O95169,Q9NZJ7,P51571,P08754 19 +Adrenal insufficiency 0.3299489631964271 0.2383926649621008 0.8115765559723653 1.0 1.0 29 P51809,P40855,Q13423,P38571,P16435 5 +Cervical spine instability 0.5886594559160951 0.2372687616476852 0.812448294810201 1.0 1.0 2 Q96L58 1 +Large fleshy ears 0.5275409836065648 0.2370131849064267 0.8126465615799638 1.0 1.0 3 Q9BZK7,O43776 2 +Aspiration pneumonia 0.3254787591194416 0.2355147254370342 0.8138092510041246 1.0 1.0 25 P16278,P04062,Q6NUK1,Q13510 4 +Limited wrist movement 0.4281749647710062 0.2340938417584218 0.814912126690615 1.0 1.0 5 O75844 1 +Abnormality of krebs cycle metabolism 0.4281190362613774 0.2339051436291992 0.8150586199333851 1.0 1.0 5 P03886 1 +Albuminuria 0.5255737704918022 0.2321953498893038 0.8163862893233238 1.0 1.0 3 P40763,Q5JRA6 2 +Duodenal stenosis 0.4272616991541923 0.2310178960947397 0.8173008989745925 1.0 1.0 5 Q9BXW9,O75419 2 +Impaired temperature sensation 0.4268836098533219 0.229747800590346 0.8182877487575233 1.0 1.0 5 O15269,P07686 2 +Abnormal paranasal sinus morphology 0.319298968020081 0.2289291865244637 0.8189239553206189 1.0 1.0 21 P10644,P04066,O00754 3 +Long nose 0.368643478472593 0.2285718908202454 0.8192016740897712 1.0 1.0 9 Q9H490 1 +Congenital hip dislocation 0.3231617473379632 0.2278043638692045 0.8197983340125901 1.0 1.0 24 Q9UHX1,Q9Y487 2 +Hydroureter 0.3442753978462862 0.2277650972244833 0.8198288619159373 1.0 1.0 14 Q7LGA3,O76024,Q9BXW9,Q16531 4 +Late onset 0.3683800154746752 0.2273723760274655 0.8201341985279804 1.0 1.0 9 Q9Y6M1,O76024,P18031,P31751 4 +Babinski sign 0.270555821600601 0.2262989975827782 0.8209688779835598 1.0 1.0 83 Q13501,O75787,Q15043,P35637,P07196,Q99720,O00400,O95831,O14773,P11166,P07602,O00754,Q9H6K4,O60313,Q6DKK2,Q9NZJ7 16 +Increased circulating gonadotropin level 0.3558203149451626 0.2258394369211133 0.821326303124156 1.0 1.0 10 P51809 1 +Abnormal circulating progesterone level 0.4010246450620887 0.2249270980943709 0.82203598815099 1.0 1.0 6 Q13144,P16435 2 +Decreased circulating progesterone 0.4010246450620887 0.2249270980943709 0.82203598815099 1.0 1.0 6 Q13144,P16435 2 +Limitation of knee mobility 0.4009808690559674 0.224759259868492 0.8221665610903541 1.0 1.0 6 Q04656 1 +Weakness of facial musculature 0.3205646641743307 0.2204212524175863 0.8255430953653933 1.0 1.0 60 Q13501,Q92796,P51798,Q9H553,Q15526,Q15043,Q9H9S5,P40855,Q9Y5P6,Q13510,Q9UHX1,Q9BUK6,P53007,O75381,Q86U42,P12235,O43819,O00429,P48651,O60313,P07196 21 +Abnormal cranial nerve physiology 0.2989911963922286 0.2190643043046506 0.8265999564494746 1.0 1.0 72 Q9BXW9,Q13501,P40855,Q9UHX1,P01889,P12235,P51798,Q9NZ08,P48651,P07602,Q15043,Q9H9S5,Q13510,Q9NZJ7 14 +Abnormality of the anus 0.3302265650533004 0.2189973567493221 0.826652106802529 1.0 1.0 50 Q9BXW9,P21964,P16615,Q5SZK8,Q6NUK1,O60826,P00533,Q92889,O95155,Q8TAA9,P16435,P53701,P48651,Q16531,Q9H9S5,O75419 16 +Proptosis 0.3200496424475712 0.2153730761423899 0.829476459577356 1.0 1.0 60 O75844,P98164,Q96JJ3,Q6NUK1,Q9NX62,P16435,O00754,Q8WVQ1,Q15043,Q96J02,O95202,P07237,Q5KU26 13 +Chorioretinal coloboma 0.3890347997373565 0.2137133228905068 0.8307706212047159 1.0 1.0 7 O15078,O60826,Q01082,P31749,Q6W2J9,Q10713 6 +Aplasia hypoplasia of metatarsal bones 0.3889745122845697 0.2134719612966518 0.8309588567229089 1.0 1.0 7 P10644,Q8WVQ1 2 +Bloody diarrhea 0.4217665012390833 0.2127531386517909 0.8315195168037857 1.0 1.0 5 P00533,Q6PGP7 2 +Bilateral talipes equinovarus 0.4213081347165486 0.2112487902013225 0.8326931406118869 1.0 1.0 5 O00754 1 +Achilles tendon contracture 0.3506367359065261 0.2106252643562399 0.8331796964319098 1.0 1.0 11 O60313,Q9H9S5 2 +Abnormality of retinal pigmentation 0.29819496409515 0.2098773289764333 0.8337634170092163 1.0 1.0 72 Q7KZN9,Q96CU9,Q9P0J0,Q92889,Q9Y6X9,P53701,Q15526,Q9NP72,Q9H9S5,P40855,Q96S66,Q8NHS3,Q15067,Q9UG56,Q9Y5P6,P03886,P03915,P18074,Q96JJ3,Q15042,P00403,O75381,Q15555,O76024,P51648 25 +Bifid scrotum 0.3967277407775667 0.2085864085743793 0.8347711215853171 1.0 1.0 6 P16435,Q96EK5 2 +Abnormality of the achilles tendon 0.3475941383769933 0.2083282543199382 0.8349726718306658 1.0 1.0 12 O60313,Q9H9S5 2 +Abnormality of the spinal cord 0.3042455824628706 0.2069624964954415 0.8360391478031755 1.0 1.0 69 Q9BXW9,P21964,Q9UHX1,P16278,Q5SZK8,Q9HC21,Q8TAA9,O00754,Q9H9S5,P07196,O95202,Q9Y4P3,P05067 13 +Obstructive sleep apnea 0.3472729005746146 0.2067065517485743 0.8362390403533784 1.0 1.0 12 P08754,Q96A33,Q16531 3 +Abnormality of the humerus 0.3310363873427175 0.2059818311391525 0.8368051036356001 1.0 1.0 16 P16435,Q04656,Q7RTS9,Q9BV10 4 +Abnormality of amino acid metabolism 0.5143813407835613 0.2056864759391005 0.8370358233219135 1.0 1.0 3 Q92889 1 +Abnormal basal ganglia mri signal intensity 0.3232352534202803 0.2045869480426875 0.837894853665246 1.0 1.0 27 P16278,Q7KZN9,Q9P0J0,Q15526,Q9BPX6,P03886,P03915 7 +Abnormal insulin level 0.3196287650899708 0.2037387981550125 0.8385576214991557 1.0 1.0 24 O75844,Q15555,P16870 3 +Albinism 0.5118032786885327 0.1998012249993348 0.8416360432344581 1.0 1.0 3 Q86YV9,O00203 2 +Primary gonadal insufficiency 0.3621942643144856 0.1995302079484345 0.8418480158687054 1.0 1.0 9 P51809,Q13144,O76024 3 +Increased blood urea nitrogen 0.4172746422347948 0.1981408875491403 0.8429348353119765 1.0 1.0 5 P15529 1 +Abnormality of the musculature of the thigh 0.3734527513231432 0.1975586223728079 0.8433904112172239 1.0 1.0 8 O14979,P50402 2 +Simple febrile seizure 0.5107468978485493 0.1974138947129555 0.843503657167415 1.0 1.0 3 P11166 1 +Neonatal onset 0.3173384706852369 0.1971175228146626 0.8437355712206327 1.0 1.0 23 Q9H490,Q13277,Q15904 3 +Pituitary hypothyroidism 0.393501805054146 0.1964998135951697 0.8442189785519192 1.0 1.0 6 P35222,Q99496,P31749,Q969G3,Q12824 5 +Decreased number of large peripheral myelinated nerve fibers 0.4153662766875144 0.1920215539015008 0.847725322016045 1.0 1.0 5 O15269 1 +Bilateral ptosis 0.3285543558806542 0.1917018040183671 0.847975792795864 1.0 1.0 16 Q5T8D3,O43819,O00429,O60313,Q15526,O95169 6 +Progressive inability to walk 0.312053426593462 0.1910383682746847 0.8484955331559465 1.0 1.0 20 Q99519,Q9H9S5,Q92581 3 +Abnormality of the optic nerve 0.3693995830267855 0.1891103166298652 0.8500063558799642 1.0 1.0 235 Q96CU9,Q9Y287,P07602,Q9H6K4,Q7LGA3,Q15067,P06280,P50897,Q9UHX1,P04350,P16278,Q6PJG6,Q86Y39,P49815,O43676,Q9H2C2,O75381,P04439,O60826,O00429,Q9H061,Q5KU26,Q8TCJ2,P51572,Q7KZN9,P04114,Q92889,Q99519,Q13277,Q9NP72,Q9H9S5,O95630,Q9BTW9,Q96S66,Q9Y5P6,O95155,Q8WWQ0,O00754,Q9H490,P01130,P10644,O43505,P21964,Q15555,P38435,O95202,Q5XKP0,P51798,Q9Y6M9,Q96PU5,P04062,P40855,Q8NHS3,Q9UG56,Q9HC21,O95831,Q9NZ08,P07942,P03886,P01889,Q15042,Q9NZJ7,O76024,O60313,P55011,Q9P0J0,Q15526,Q15043,Q9NVI7,Q9BPX6,P03915,O96000,P00403,O95169,Q3ZCQ8,O43292,P78318,P07196 78 +Short chin 0.3446459905539759 0.1815549665652337 0.8559319928498166 1.0 1.0 11 Q96J02,O75844,P42345 3 +Full cheeks 0.3251151517682389 0.1814904688373487 0.8559826136921476 1.0 1.0 33 P16870,Q9UHX1,Q96JJ3 3 +Pneumonia 0.3252449761311022 0.1810299507312829 0.8563440671117464 1.0 1.0 51 P04062,Q9BV10,P16278,Q6NUK1,O00754,P15260,Q13510 7 +Nyctalopia 0.3172262466933455 0.1790904941296239 0.8578666459257807 1.0 1.0 25 Q9Y287,Q15555,P38435 3 +Abnormal venous morphology 0.3195064805964312 0.1788552624587292 0.858051351646852 1.0 1.0 27 P04062,P21964,Q9Y487,Q04656,Q6NUK1,P36543 6 +Photopsia 0.5601442150114622 0.1783604141271862 0.8584399357282877 1.0 1.0 2 Q99496 1 +Uveal melanoma 0.5601442150114622 0.1783604141271862 0.8584399357282877 1.0 1.0 2 Q99496 1 +Choroidal melanoma 0.5601442150114622 0.1783604141271862 0.8584399357282877 1.0 1.0 2 Q99496 1 +Mydriasis 0.5601442150114622 0.1783604141271862 0.8584399357282877 1.0 1.0 2 Q99496 1 +Metamorphopsia 0.5601442150114622 0.1783604141271862 0.8584399357282877 1.0 1.0 2 Q99496 1 +Inferior lens subluxation 0.5601442150114622 0.1783604141271862 0.8584399357282877 1.0 1.0 2 Q99496 1 +Decreased lacrimation 0.3798493864596161 0.1775919517614267 0.859043445633547 1.0 1.0 7 Q10567,Q92889,P55011 3 +Pointed chin 0.3212376909272275 0.1767550971435589 0.8597007608936253 1.0 1.0 29 Q7LGA3,Q9H490,Q9Y4P3,P11233,P36543 5 +Abnormal ovarian morphology 0.3180088141858257 0.1763067112749 0.8600529897888669 1.0 1.0 26 P10644,P51809,P16435,P31751 4 +Neonatal hyperbilirubinemia 0.5009836065573734 0.1760224018666402 0.8602763430791998 1.0 1.0 3 P36551,P43034 2 +Abnormal anterior horn cell morphology 0.3876234139412416 0.1748897246928438 0.8611662843480099 1.0 1.0 6 Q13510 1 +Epistaxis 0.3254841515723483 0.1742260308597402 0.8616878287176515 1.0 1.0 16 P10644,P04062,P38435 3 +Spastic gait 0.3124529092161214 0.1740199542481459 0.8618497802711398 1.0 1.0 22 Q15043,Q9NVI7,Q9Y619,O75787 4 +Male reproductive system neoplasm 0.3253049001827885 0.173212325873074 0.862484535437547 1.0 1.0 16 P10644,P51809,Q13423 3 +Sclerosis of skull base 0.4989410224996167 0.1717020284494981 0.863671791027611 1.0 1.0 3 Q14739 1 +Rapidly progressive 0.3436402713106073 0.1684529136853043 0.86622698368818 1.0 1.0 10 Q14108 1 +Dysarthria 0.3159177811448326 0.1670218204558657 0.8673528798429491 1.0 1.0 149 O75569,Q13501,P61916,Q9Y4P8,Q8IV08,Q7KZN9,Q96CU9,Q9P0J0,P07602,Q15526,P04062,O15118,P98155,O00754,P15586,P07686,Q14108,Q6DKK2,Q9NZJ7,P12235,P35637,O75503,O43292,O14773,O76024,P11166,P51648,P07196,Q5XKP0,Q9Y4P3 30 +Weakness of muscles of respiration 0.3221846449543428 0.1654857998215416 0.8685616258392466 1.0 1.0 32 Q969X5,P12235,Q15067,Q7RTS9,Q9Y6X9,O95831,P10253,Q15526,P50402,Q13510 10 +Abnormality of the musculature of the lower limbs 0.3151751659028897 0.1653290174309021 0.8686850204747318 1.0 1.0 25 P50402,O14979,Q9Y5P6,P53007,O00592,Q9NW15,P07196,Q9H9S5 8 +Large basal ganglia 0.3322913008976533 0.1637326173547031 0.8699416391103034 1.0 1.0 14 Q9NZ01,Q96N66,P55011 3 +Abnormal visual field test 0.4061679790026233 0.1632916244626643 0.8702888281067833 1.0 1.0 5 P35222,P31749,Q99496,Q12824 4 +Heteronymous hemianopia 0.4061679790026233 0.1632916244626643 0.8702888281067833 1.0 1.0 5 P35222,P31749,Q99496,Q12824 4 +Visual acuity test abnormality 0.4061679790026228 0.163291624462663 0.8702888281067844 1.0 1.0 5 P25054,P31749,Q99496,Q12824 4 +Hemifacial spasm 0.4061679790026224 0.1632916244626618 0.8702888281067853 1.0 1.0 5 P31749,Q10713,Q99496,Q12824 4 +Abnormality of the metaphysis 0.3224066904154388 0.1620251438378892 0.8712860535623896 1.0 1.0 52 Q9HC07,Q14739,P16278,Q9UG56,Q04656,P51798,Q7RTS9,O95831,Q8WVQ1,P07237,Q96HY6 11 +Impaired social interactions 0.3242083609593196 0.1536852204650801 0.8778579386878045 1.0 1.0 46 Q9UHX1,O96000,Q9Y6M9,Q96CU9,Q9P0J0,O00592,Q10471,Q86Y39,O43676,Q2TAA5,P11166,Q5KU26,Q5XKP0,P03886 14 +Mildly elevated creatine kinase 0.310738888899222 0.1535278340263607 0.877982042118687 1.0 1.0 23 Q13501,Q9H9S5 2 +Abnormality of dna repair 0.3816002459878209 0.1533243782289592 0.8781424769187907 1.0 1.0 6 Q92889,Q9BXW9 2 +Hypertrichosis 0.2803847275751427 0.1529526883044563 0.878435585436177 1.0 1.0 102 Q7KZN9,Q9P0J0,Q99519,Q15526,Q96A33,P54802,P19022,P53634,O00754,Q86UE8,P15586,Q9H490,P03886,P03915,Q9UHX1,Q15042,P16278,Q6NUK1,P00403 19 +Abnormal caudate nucleus morphology 0.3401502226968975 0.1525077305934773 0.8787864936278269 1.0 1.0 10 O43819,O95169,Q15526 3 +Abnormality of lower limb joint 0.3241495526610456 0.1510230942760282 0.8799574982427423 1.0 1.0 163 O75844,P55011,P51798,P07602,Q7LGA3,Q96A33,Q9H9S5,Q96PU5,O95831,Q9Y619,O00754,Q13510,O75787,Q9UHX1,P16278,Q04656,P23786,Q96HY6,Q9NZJ7,P21964,Q9Y487,Q9NX62,Q6NUQ1,P08236,Q86XL3,P16435,Q8WVQ1,O95202,Q9Y4P3,P36543 30 +Abnormality of the ankles 0.3238101662423087 0.1495095724241023 0.8811515565603287 1.0 1.0 40 O75844,O75787,P07602,O00754,Q15043,Q9Y4P3,Q9NZJ7 7 +Melanoma 0.3069926119057005 0.1484038343505026 0.8820240742064807 1.0 1.0 21 P53634 1 +Abnormality of the anterior fontanelle 0.321114973853418 0.1479495782996218 0.8823825608843454 1.0 1.0 34 O75381,P98164,P40855,Q9Y487,P36543,Q04656,Q6NUK1,P42345,P16435,Q9Y619,O75419 11 +Abnormal morphology of the musculature of the neck 0.3325912997971301 0.1479316875263687 0.882396680295823 1.0 1.0 13 Q99720,O75569,P35637 3 +Extrapyramidal dyskinesia 0.4867686844131932 0.1470828930679315 0.8830665923733618 1.0 1.0 3 P11166 1 +Mixed hearing impairment 0.3715094615777815 0.1459913251600912 0.8839282365745473 1.0 1.0 7 Q9NWM8,O00754 2 +Neoplasm of the tracheobronchial system 0.4186097473709191 0.1456494546549257 0.8841981250649078 1.0 1.0 4 Q14145,P00533 2 +Septate vagina 0.5414618157980889 0.1455957733224554 0.884240504829122 1.0 1.0 2 Q9UBM7 1 +Abnormal shape of the frontal region 0.2766397204551329 0.1446385319626867 0.8849962730025163 1.0 1.0 98 Q15392,P51798,Q99519,Q96J02,P07237,Q9NVI7,P19022,Q15067,P04066,Q9Y619,O00754,P15586,Q9BXW9,P16278,Q14739,Q9Y487,P16435,P48651,O95202,P14543,P13073 21 +Corneal neovascularization 0.3790728360545567 0.1444553736494049 0.8851408934365528 1.0 1.0 6 P21964,P18074 2 +Abnormality of upper limb epiphysis morphology 0.3285573835202304 0.1443970080128208 0.885186979310769 1.0 1.0 14 P10644,O95202,P16435 3 +Otitis media 0.3202491606223266 0.1431755554697543 0.8861515348148146 1.0 1.0 52 Q14739,P21964,Q03518,P51798,O00754,Q86UE8,O95202,Q96A33 8 +Fetal ultrasound soft marker 0.3146345740512682 0.1419202841003229 0.8871429720936872 1.0 1.0 17 O75381,P16435,P40855,Q13501 4 +Multiple joint dislocation 0.5388397246804225 0.1413665575820017 0.8875803720993218 1.0 1.0 2 Q96L58 1 +Flattened femoral epiphysis 0.5388397246804224 0.1413665575820017 0.8875803720993218 1.0 1.0 2 Q9NUQ7 1 +Choking episodes 0.5385119632907192 0.1408442592534311 0.8879929777118505 1.0 1.0 2 P53007 1 +Staring gaze 0.5385119632907192 0.1408442592534311 0.8879929777118505 1.0 1.0 2 P53007 1 +Thin skin 0.3137109410187347 0.1395741956662751 0.8889964298925248 1.0 1.0 27 P10644,O75844,P17612,Q9H4L7,Q92889,Q9Y619,P48651,Q96PU5 8 +Aplasia hypoplasia of the cerebellar vermis 0.3034578000425143 0.1394754156516554 0.8890744815095357 1.0 1.0 66 Q15042,Q9Y487,P07942,Q9HC21,Q6NUK1,P23786,Q8NFH4,Q9H490,P14543,O43505,Q9H9S5 11 +Neonatal insulin dependent diabetes mellitus 0.5375286791215932 0.1392858221252827 0.8892242929759626 1.0 1.0 2 A5YKK6 1 +Moderate albuminuria 0.5375286791215902 0.1392858221252777 0.8892242929759666 1.0 1.0 2 Q5JRA6 1 +Abnormal clavicle morphology 0.3069473213281333 0.1383975298113435 0.8899262491562301 1.0 1.0 22 O75844,Q14739,Q04656,Q9Y619,P48651 5 +Falls 0.3692953358493489 0.1378034115931547 0.8903957880250943 1.0 1.0 7 O75787 1 +Pes planus 0.2874877218465207 0.1375019863483292 0.8906340227798621 1.0 1.0 74 Q9BXW9,O75787,Q9UHX1,Q9Y487,P98155,P55795,P53634,Q04656,Q7RTS9,Q15555,Q86UE8,Q9NWM8,Q8WVQ1,Q9Y4P3,P36543 15 +Abnormal vagina morphology 0.3135176574209055 0.1355253336906783 0.8921965356430421 1.0 1.0 17 P51809,Q5SZK8 2 +Central adrenal insufficiency 0.4144129350298056 0.1355032949159417 0.8922139593190717 1.0 1.0 4 Q9NRG9,Q9NSE4 2 +Follicular thyroid carcinoma 0.4803278688524579 0.1348437103130829 0.8927354455852776 1.0 1.0 3 Q9UNW1,P21912 2 +Adrenal hypoplasia 0.3684214858462531 0.1345958459298286 0.8929314261883485 1.0 1.0 7 O75844,O60826 2 +Hypoplasia of penis 0.278193925927558 0.1338633456081171 0.8935106353236948 1.0 1.0 101 P51809,Q9NVI7,P19022,P42892,P16870,Q9BV10,Q15042,Q5SZK8,Q15555,Q6NUK1,O95470,P16435,Q9Y619,P53701,Q9Y4P3,O43505,Q9H9S5,P46977 18 +Congenital nonbullous ichthyosiform erythroderma 0.4135504318865747 0.1334508007533059 0.8938368714629146 1.0 1.0 4 P04062 1 +Abnormal circulating estrogen level 0.3323019483816927 0.1333423505685602 0.8939226357138974 1.0 1.0 12 P51809 1 +Abnormal proximal phalanx morphology of the hand 0.3955402831514731 0.1317396369714453 0.8951902329590493 1.0 1.0 5 Q9BXW9 1 +Abnormal blood sodium concentration 0.3318006861084999 0.1309656278880206 0.8958024981302903 1.0 1.0 12 Q13423 1 +Dental crowding 0.3134901201241796 0.1306390921730998 0.8960608166366311 1.0 1.0 28 O75844,Q5SZK8,Q92643,Q96A33,P36543 5 +High anterior hairline 0.3054368166160057 0.1287731592400314 0.8975371444915357 1.0 1.0 22 Q7LGA3,O95202,P98164 3 +Abnormal nipple morphology 0.3132060301736388 0.1267922213581107 0.8991048525052501 1.0 1.0 58 Q2TAA5,Q7LGA3,Q9NP72,Q96A33,P19022,Q15067,P08069,Q8WWQ0,P18074,O14678,Q5SZK8,Q6NUK1,P23786,Q9BZK7,Q96EK5,P10586,Q9BV10,Q15555,O60826,O95202 20 +Reduced circulating prolactin concentration 0.3933727034120752 0.1255287677896658 0.9001049517556894 1.0 1.0 5 P31749,Q12824,Q99496,Q969G3 4 +Pulmonary fibrosis 0.2999127291099869 0.1245290749847202 0.9008963810368882 1.0 1.0 19 Q8IZA0,P09601 2 +Angular cheilitis 0.4097056512861957 0.1244380458028258 0.9009684512412028 1.0 1.0 4 Q14574 1 +Erythrocyte inclusion bodies 0.474426229508201 0.1241108537368246 0.9012275045665304 1.0 1.0 3 P08865,P11413 2 +Multiple rows of eyelashes 0.4744262295081858 0.1241108537367977 0.9012275045665517 1.0 1.0 3 O60716,Q9Y2Z4 2 +Absent thumbnail 0.5273680760406365 0.1239206652625843 0.9013780905502944 1.0 1.0 2 Q9H936 1 +Red green dyschromatopsia 0.4742999780687803 0.1238862916346671 0.9014053070188416 1.0 1.0 3 O60313 1 +Abnormality of the pubic hair 0.3730425150527995 0.1237389683650651 0.9015219564530356 1.0 1.0 6 P51809 1 +Hand polydactyly 0.3100366443209063 0.1230758206091854 0.9020470580499004 1.0 1.0 26 Q14739,Q9BXW9,Q9UHX1,P54198,P21964,Q15067,O43924,O60826,Q9UBM7,O95202 10 +Broad columella 0.4088946122670297 0.1225654899183087 0.9024511834027078 1.0 1.0 4 P36543 1 +Abnormal proportion of cd4 positive t cells 0.3725915709446192 0.1222154965514276 0.9027283539825746 1.0 1.0 6 O75787 1 +Multifocal seizures 0.4081901189422949 0.1209470647643692 0.9037329634752772 1.0 1.0 4 Q10471 1 +Abnormality of lower lip 0.2923650911576659 0.1197255006124535 0.9047005990886072 1.0 1.0 71 P04062,Q15042,P04066,P06280,Q6NUK1,Q99519,Q9Y619,P11166,Q7LGA3,P15586 10 +Abnormality of the nail 0.2855477517410569 0.1189213103937235 0.9053376983150252 1.0 1.0 112 P10644,O75844,Q14739,P42892,P10321,Q9BV10,Q15042,Q9Y487,P16615,P53634,P04066,Q6NUK1,P23786,P00533,Q9Y619,P53701,O95202,Q14574 18 +Prenatal maternal abnormality 0.3266527400931737 0.1187721984822173 0.9054558351391102 1.0 1.0 13 P15529,Q14739,Q8TAA9 3 +Atrial arrhythmia 0.3638009565545211 0.1178653730659786 0.9061743302441684 1.0 1.0 7 P12235 1 +Telangiectasia of the skin 0.3004632793927869 0.1174791245084913 0.9064803857128428 1.0 1.0 20 Q8IZA0,P06280,Q96JJ3 3 +Round face 0.302013553192221 0.1169899143151341 0.906868045807756 1.0 1.0 21 P10644,P16870 2 +Shallow orbits 0.3428689791941705 0.1168847540460529 0.9069513798416158 1.0 1.0 9 O75844 1 +Neuralgia 0.4060347654968794 0.1160426860272469 0.9076187117344257 1.0 1.0 4 P31749,Q99496,Q12824 3 +Transient global amnesia 0.4060347654968794 0.1160426860272469 0.9076187117344257 1.0 1.0 4 P31749,Q99496,Q12824 3 +Secondary growth hormone deficiency 0.4060347654968794 0.1160426860272469 0.9076187117344257 1.0 1.0 4 P31749,Q99496,Q12824 3 +Hypothalamic hypothyroidism 0.4060347654968794 0.1160426860272469 0.9076187117344257 1.0 1.0 4 P31749,Q99496,Q12824 3 +Brain stem compression 0.4060347654968794 0.1160426860272469 0.9076187117344257 1.0 1.0 4 P31749,Q99496,Q12824 3 +Progressive pulmonary function impairment 0.4060347654968794 0.1160426860272469 0.9076187117344257 1.0 1.0 4 P31749,Q99496,Q12824 3 +Intracranial meningioma 0.4060347654968794 0.1160426860272469 0.9076187117344257 1.0 1.0 4 P31749,Q99496,Q12824 3 +Ear pain 0.4060347654968794 0.1160426860272469 0.9076187117344257 1.0 1.0 4 P31749,Q99496,Q12824 3 +Elbow flexion contracture 0.3076404043904331 0.1157645590208598 0.9078391394203682 1.0 1.0 25 Q7LGA3,P23786,P16435,P50402 4 +Flat acetabular roof 0.3897117188830069 0.1152157436763742 0.9082741201296092 1.0 1.0 5 Q8WVQ1 1 +Abnormality of the nasal dorsum 0.3163519643396662 0.1151407122522113 0.9083335907639154 1.0 1.0 53 P10644,O75844,P16278,Q04656,O00754,Q8WVQ1,Q96J02,O95202 8 +Constipation 0.2720176086457704 0.1141031017925721 0.909156063410669 1.0 1.0 95 P55011,O00592,Q7LGA3,P04062,Q8TAA9,Q86UE8,P03886,P03915,Q13423,P55795,Q04656,Q10471,P00403,P12235,P42892,P21964,O76024,P16435,Q9Y4P3 19 +Retinal arteriolar tortuosity 0.3313945708995365 0.1135703541890879 0.9095783891911836 1.0 1.0 10 P21964 1 +Arm dystonia 0.4675897451413993 0.1122548715263999 0.9106213228722968 1.0 1.0 3 Q99720 1 +Chronic otitis media 0.3056924776111198 0.1119404080640931 0.9108706569301596 1.0 1.0 24 Q03518,O95202,P21964 3 +Abnormality of the zygomatic bone 0.2806692570675202 0.1116864901110518 0.911071991633984 1.0 1.0 76 Q9HC07,P10644,Q14739,P98164,P21964,Q15042,Q9Y487,O95831,P16435,O00754,Q8WVQ1,Q9H490,Q9Y4P3 13 +Progressive microcephaly 0.3188687789600453 0.1093269126205077 0.9129432013454865 1.0 1.0 42 Q5T8D3,Q9Y487,Q9BV10,P36543,Q9BT22,Q9HC21,O75419,Q6PJG6,P11166,P50897,Q15043,Q5KU26,O95630 13 +U shaped upper lip vermilion 0.4655737704918005 0.1088769240991246 0.9133001097215384 1.0 1.0 3 O60762,P28482 2 +Cerebellar malformation 0.308824183630199 0.1069738307647863 0.9148097406272816 1.0 1.0 60 Q9Y487,Q8TAA9,O43505,P16435,O00754,P23786,P14543,Q9Y4P3,Q9H9S5,P36543 10 +Abnormality of the extraocular muscles 0.5149131432317164 0.1068962008444158 0.9148713272093328 1.0 1.0 2 P43243 1 +Misalignment of incisors 0.4016011529805714 0.1061786073992194 0.9154406438088304 1.0 1.0 4 Q9BSJ2,Q8WVM7 2 +Chronic constipation 0.3061283313665966 0.1060165667157117 0.9155692079244004 1.0 1.0 25 Q7LGA3,P04062,P55795,P55011 4 +Pulmonary artery dilatation 0.3283279653281122 0.1059226579781016 0.9156437167290634 1.0 1.0 11 Q7LGA3 1 +Grammar specific speech disorder 0.5126188135037634 0.1039733153714631 0.9171905250214796 1.0 1.0 2 Q9UQN3 1 +Senile plaques 0.5126188135037634 0.1039733153714631 0.9171905250214796 1.0 1.0 2 Q9UQN3 1 +Alexia 0.5126188135037634 0.1039733153714631 0.9171905250214796 1.0 1.0 2 Q9UQN3 1 +Expressive aphasia 0.5126188135037634 0.1039733153714631 0.9171905250214796 1.0 1.0 2 Q9UQN3 1 +Elevated tissue non specific alkaline phosphatase 0.5126188135037599 0.1039733153714589 0.9171905250214828 1.0 1.0 2 Q13043 1 +Reduced vital capacity 0.5126188135037595 0.1039733153714583 0.9171905250214832 1.0 1.0 2 P06753 1 +Apneic episodes precipitated by illness fatigue stress 0.5122910521140498 0.1035610972960434 0.9175176614650132 1.0 1.0 2 P53007 1 +Cheilitis 0.385454649820957 0.1035070405952858 0.9175605619231576 1.0 1.0 5 Q14574 1 +Bilateral cleft lip 0.4622950819672095 0.1034979773258156 0.9175677547351022 1.0 1.0 3 O60716,Q9NXE4 2 +Delayed closure of the anterior fontanelle 0.320374939634995 0.1031509174655863 0.9178431942188124 1.0 1.0 14 Q04656,P40855,Q9Y487 3 +Abnormal tricuspid valve morphology 0.3276071849201302 0.102711898491376 0.9181916299632228 1.0 1.0 11 P21964 1 +Impaired smooth pursuit 0.3232589412316159 0.102471493043551 0.9183824389733632 1.0 1.0 13 O00754,P46977,Q9BTW9 3 +Death in adulthood 0.316520607912402 0.1019115424207647 0.918826888139948 1.0 1.0 15 P05067,Q92581 2 +Synostosis involving bones of the hand 0.3230292393244812 0.1013780980596661 0.9192503221052444 1.0 1.0 13 P16435,Q04656 2 +Abnormal oral physiology 0.3093617228105927 0.1011366155290828 0.9194420120608288 1.0 1.0 59 P10644,Q14739,Q13501,P55011,O75787,P01889,P35637,Q15165,P55795,Q68CQ7,Q92581,P15586 12 +Aplasia hypoplasia of the eyelid 0.3252590315436108 0.1004609624665909 0.9199783734426648 1.0 1.0 12 Q5SZK8 1 +Abnormal glomerular mesangium morphology 0.2959552613250269 0.100397271592795 0.9200289357774468 1.0 1.0 19 Q8N1F7,Q92621,Q8NFH4,O95470,Q96J84 5 +Muscular hypotonia of the trunk 0.2797023611150415 0.1000585175362489 0.9202978682117248 1.0 1.0 76 Q9NVI7,Q96N66,Q16625,Q9HC21,Q5XKP0,P07602,Q2TAA5,O00754,Q15043,O60313,P17900,Q96PU5,Q9NZJ7 13 +Birth length greater than 97th percentile 0.5093411996066751 0.0999108188104913 0.9204151271622818 1.0 1.0 2 Q15022 1 +Duodenal adenocarcinoma 0.4599999999999935 0.0998171644748236 0.9204894808270834 1.0 1.0 3 P25054,P78549 2 +Adenocarcinoma of the small intestine 0.4599999999999935 0.0998171644748236 0.9204894808270834 1.0 1.0 3 P25054,P78549 2 +Scaling skin 0.3385933404706714 0.0995760926850227 0.9206808747462464 1.0 1.0 9 O75844 1 +Abnormality of the humeroradial joint 0.348646693157194 0.0991483126957023 0.9210205130489966 1.0 1.0 8 P10644,P16435 2 +Abnormal cerebral vascular morphology 0.2922918767891596 0.0971956294945361 0.922571038771776 1.0 1.0 70 P10644,P04062,O75844,Q04656,P06280,P38435,P15529,P04114,O76024,P10253,P03886,Q9Y4P3,P23786,P01130,P05067,P03915 16 +Pulmonary hypoplasia 0.3067623249059094 0.0937308420557729 0.9253229697042628 1.0 1.0 27 O75844,Q14739,Q5SZK8,Q6NUK1,Q8TAA9 5 +Flared metaphysis 0.3266689368749703 0.0932241915994851 0.92572545595804 1.0 1.0 10 Q14739,Q96HY6 2 +Cholecystitis 0.346699551338865 0.0919166816265207 0.9267642375480633 1.0 1.0 8 P07602 1 +Muscle fiber inclusion bodies 0.3262801063467633 0.0915719005972825 0.9270381776982716 1.0 1.0 10 P07196,O43676,Q9Y5P6 3 +Primary amenorrhea 0.3064133513744007 0.0914670812749713 0.9271214618991936 1.0 1.0 27 P16870,Q16740,P51809 3 +Neuronal loss in basal ganglia 0.3558547893305503 0.0900252713599812 0.9282671327220852 1.0 1.0 7 O43819,O95169,Q15526 3 +Reduced tendon reflexes 0.3155264098618267 0.089886498437656 0.9283774104034416 1.0 1.0 157 Q13501,P39210,P05023,Q9BT22,P04114,O00592,P07602,Q9H6K4,Q15526,Q9H9S5,P54802,P04062,P56192,P40855,Q15067,Q99720,Q6DD88,Q9HC21,O95831,Q16637,Q8TAA9,Q9Y6B6,P03886,Q13510,P03915,O14979,O75787,Q04656,Q9H2C2,O43505,P10253,P50402,Q9NZJ7,P12235,P35637,O60313,O15269,P07196,P51149 39 +Abnormal abdomen morphology 0.3494024746112359 0.0888866217796369 0.9291720157379916 1.0 1.0 212 Q9HC07,P61916,Q16625,P09601,P39210,Q9BT22,P10619,P51798,Q9Y6M9,Q99519,P07602,P15260,Q15526,Q96J02,Q96A33,P54802,P04062,Q9NVI7,P56192,O15118,P40855,P04066,Q9HC21,Q07021,Q5HYI8,Q9NZ08,Q9Y619,O00754,P15586,P03886,Q13510,P03915,P10644,O75787,P01889,P16278,P38571,Q01844,P07686,Q15904,Q86Y39,O43676,Q14108,P23786,P10253,Q96HY6,Q9NZJ7,Q14739,P21964,P09622,Q6NUQ1,P08236,P11166,P31751 54 +Facial hemangioma 0.3933609800295243 0.0886548458752247 0.9293562189385534 1.0 1.0 4 P16435,O60826 2 +Focal tonic seizure 0.4985250737463064 0.0874305266601775 0.9303293055117444 1.0 1.0 2 Q9H936 1 +Hyperconvex fingernails 0.3617424079955709 0.086679190536429 0.9309265176971496 1.0 1.0 6 O95202 1 +Abnormal head movements 0.3231463172778856 0.0831031408363189 0.9337695284611592 1.0 1.0 11 Q99720,P11166 2 +Delayed ability to sit 0.3183993170572968 0.0796142109294164 0.9365440924083764 1.0 1.0 13 P10253,Q10471 2 +Decreased testicular size 0.2940813548434977 0.0786733238115468 0.9372924642099268 1.0 1.0 20 P51809,Q92889,Q8WWQ0,Q9NP72,O43505 5 +Thick lower lip vermilion 0.3144093262453253 0.0782945482178936 0.93759375404415 1.0 1.0 48 P04066,P06280,Q99519,Q9Y619,P15586 5 +Cutaneous melanoma 0.3879960642833688 0.0778162009160929 0.9379742590596672 1.0 1.0 4 P11802,Q01831,Q99496 3 +Congenital bilateral hip dislocation 0.4863979023271015 0.0750690099416415 0.9401598047135812 1.0 1.0 2 Q02809 1 +Colon cancer 0.2971576189026907 0.0732772250769063 0.9415855147243783 1.0 1.0 18 Q5HYI8 1 +Keratoconjunctivitis 0.3218249075763837 0.0728835906218873 0.9418987519984348 1.0 1.0 10 Q9NZ08,P01889 2 +Decreased activity of mitochondrial complex iv 0.3107241427158277 0.0726539056388868 0.942081529528537 1.0 1.0 15 Q9Y2R0,Q70HW3 2 +Abnormality of skin pigmentation 0.2959782668122896 0.0707640970172122 0.9435855065910892 1.0 1.0 131 O75844,P55011,P51798,P07602,P53701,Q7LGA3,P04062,P53634,Q8IZA0,P03886,P03915,P10644,Q9BXW9,Q13423,Q06136,P16615,Q04656,P00403,Q9NZJ7,Q14739,P21964,Q15555,P51648 23 +Dermal translucency 0.3311917669616487 0.0705267375159112 0.9437744200710922 1.0 1.0 9 O75844 1 +Slender build 0.3162651741973216 0.0697627054753001 0.944382531543803 1.0 1.0 13 P10644,Q3ZCQ8,P17612 3 +Conjunctival hamartoma 0.4801704359226434 0.0693614330172702 0.9447019269467772 1.0 1.0 2 P21912 1 +Asymmetry of the thorax 0.4801704359226416 0.0693614330172685 0.9447019269467788 1.0 1.0 2 Q14696 1 +Dysgerminoma 0.480170435922641 0.0693614330172679 0.9447019269467792 1.0 1.0 2 P35222 1 +Ovarian papillary adenocarcinoma 0.480170435922641 0.0693614330172679 0.9447019269467792 1.0 1.0 2 P35222 1 +Sirenomelia 0.4801704359226382 0.0693614330172654 0.9447019269467812 1.0 1.0 2 P21281 1 +Venous malformation 0.4801704359226372 0.0693614330172646 0.9447019269467818 1.0 1.0 2 Q92990 1 +Blepharophimosis 0.3137093170288094 0.0687407750364519 0.9451959611630916 1.0 1.0 44 O75844,P55011,Q15555,Q9Y619,Q86UE8,Q7LGA3,Q9Y4P3 7 +Upper limb undergrowth 0.2962849533886412 0.0683759126764731 0.9454863958453528 1.0 1.0 18 P10644,Q14739,Q9BV10 3 +Abnormality of mouth size 0.2906703518974192 0.0679145038534671 0.9458536930056948 1.0 1.0 124 Q15392,O75844,P55011,Q7LGA3,P04062,Q9NVI7,P42345,P08069,Q9Y619,Q01105,Q86UE8,P15586,Q9H490,O75419,Q15042,P16278,P55795,Q5SZK8,Q6NUK1,Q16531,P51571,P21964,Q96C86,Q9Y487,Q15555,Q9NX62,P08754,P11166,P16435,P48651,Q8WVQ1,Q9Y4P3 32 +Abnormality of the dorsal column of the spinal cord 0.4377049180327836 0.0676397518996848 0.946072410404277 1.0 1.0 3 P54886,Q8WVX9 2 +Death in childhood 0.3009688789499696 0.0648095886824219 0.948325606838584 1.0 1.0 26 Q8TCJ2,Q04656,Q6NUQ1,P07686,O75431,Q9NPL8,Q96AX1,Q9H9S5,P18074 9 +Lens subluxation 0.4350819672131129 0.0642740097578197 0.9487520478621918 1.0 1.0 3 Q99496,O75533 2 +Congenital malformation of the left heart 0.4339499113233188 0.0628481233787028 0.9498874446687882 1.0 1.0 3 O60826 1 +Stroke 0.3063110916285403 0.0622402339990471 0.9503715224839548 1.0 1.0 31 O75844,P06280,O76024,Q9Y4P3,P03886,P05067,P03915 7 +Hypoplasia of the frontal lobes 0.3381923989585937 0.0612401403157446 0.9511679623576677 1.0 1.0 8 P35606,Q86XL3,Q9UBM7 3 +Recurrent fractures 0.3078740152311113 0.0606401447229581 0.9516458014704798 1.0 1.0 33 P16435,Q04656,Q13501,P51798 4 +Abnormal platelet morphology 0.368438320209971 0.0598425330392153 0.9522810497911688 1.0 1.0 5 P12814,Q86YV9,O00203,P27797 4 +Decreased cd4 cd8 ratio 0.4314754098360587 0.0597871866451458 0.9523251308968366 1.0 1.0 3 O00203,Q9H0U3 2 +Lactose intolerance 0.4311475409836056 0.0593873411523067 0.9526435955609928 1.0 1.0 3 Q14566,P42345 2 +Severe varicella zoster infection 0.4311475409836003 0.0593873411523002 0.952643595560998 1.0 1.0 3 P17812,Q9H0U3 2 +Abnormality of the palm 0.2825755900184442 0.0591818838824423 0.9528072389155952 1.0 1.0 114 Q14126,Q96J02,P07858,P40855,P53634,P42345,P08069,O95831,Q9Y619,Q9UID3,P10644,P42167,Q9UHX1,Q06136,P16615,Q04656,Q6NUK1,Q7RTS9,Q02487,Q9BZK7,Q14739,Q9Y487,Q15555,P16435,P48651,O95202 26 +Generalized limb muscle atrophy 0.3376026272578052 0.0591702408058352 0.952816512495297 1.0 1.0 8 Q9Y606,P49589,O43819,P06753,Q9Y5P6,Q9Y2Z4,Q6PI48 7 +Alternating esotropia 0.4308196721311478 0.0589888310039847 0.9529610041887124 1.0 1.0 3 P25054,Q14738 2 +Reticular hyperpigmentation 0.4657489347754708 0.05771260551634 0.9539775526832625 1.0 1.0 2 P09884 1 +Tracheobronchomalacia 0.4654211733857626 0.0574722177012661 0.9541690365804604 1.0 1.0 2 P63000 1 +Abnormality of body mass index 0.4288524590163919 0.0566257332231694 0.9548433352816884 1.0 1.0 3 P42858,Q9UJS0 2 +Myopathy 0.2636867988951686 0.0554397698411877 0.9557881127893711 1.0 1.0 90 Q13501,Q14126,Q9H9S5,Q07021,O00754,Q9Y6B6,P03886,P03915,P10644,O14979,P42167,P00403,Q86Y39,O43676,P23786,Q9NWM8,P50402,P12235,O76024,O60313,Q9Y4P3 21 +Bilateral cleft palate 0.4621435594886823 0.0551254541135334 0.9560385175227886 1.0 1.0 2 O60716 1 +Non midline cleft palate 0.4621435594886823 0.0551254541135334 0.9560385175227886 1.0 1.0 2 O60716 1 +Bilateral cleft lip and palate 0.4621435594886823 0.0551254541135334 0.9560385175227886 1.0 1.0 2 O60716 1 +Abnormality of the proximal phalanx of the thumb 0.4614880367092629 0.0546684340748546 0.9564026176991978 1.0 1.0 2 Q15233 1 +Symphalangism of middle phalanx of finger 0.4614880367092629 0.0546684340748546 0.9564026176991978 1.0 1.0 2 Q15233 1 +Adipose tissue loss 0.3266898668140484 0.0534485721529037 0.957374505510422 1.0 1.0 9 Q92889,O75844,P18074 3 +Cerebral hamartoma 0.4247425684127635 0.0518423439626895 0.9586543152929904 1.0 1.0 3 P49815 1 +Synostosis of carpals tarsals 0.3259942394394448 0.0508507636362418 0.959444439638106 1.0 1.0 9 Q04656 1 +Carpal synostosis 0.3259942394394448 0.0508507636362418 0.959444439638106 1.0 1.0 9 Q04656 1 +Red eye 0.2893474998152184 0.0507536111916828 0.9595218561085256 1.0 1.0 20 Q9NZ08,P01889,P02786 3 +Limited elbow movement 0.3091932800280632 0.0506015502508907 0.9596430274882136 1.0 1.0 37 Q04656,Q7RTS9,P16435,P48651,Q7LGA3,Q96J02,P23786,P50402 8 +Deviation of the 2nd finger 0.3645558609043065 0.0506010863319156 0.9596433971684162 1.0 1.0 5 Q8WVQ1 1 +Aplasia hypoplasia of the lungs 0.3054850524927686 0.0505207594196541 0.9597074069017348 1.0 1.0 32 O75844,Q14739,Q5SZK8,Q6NUK1,Q8TAA9,O95202 6 +Abnormality of the inner ear 0.3152969577037554 0.0497408776897885 0.9603288810736332 1.0 1.0 11 Q9Y619 1 +Abnormal activity of mitochondrial respiratory chain 0.3103869083273661 0.0482128540428416 0.9615466060567734 1.0 1.0 49 Q70HW3,Q3ZCQ8,Q9UBX3,O96000,Q9Y6M9,Q7KZN9,Q9P0J0,Q86Y39,O43676,Q15526,Q9Y2R0,P03886,P13073 13 +Agenesis of cerebellar vermis 0.4196721311475339 0.046223416797651 0.9631321785142593 1.0 1.0 3 O43924,Q10713 2 +Abnormal peripheral nervous system physiology 0.3104015655070566 0.0461668724921865 0.9631772462298628 1.0 1.0 48 P39210,Q6DD88,Q99720,O95831,Q99519,Q9Y619,P07602,O60313,O15269,P07196,P51149,Q9NZJ7 12 +Right ventricular hypertrophy 0.3702853394555575 0.0452533679885774 0.9639053562846842 1.0 1.0 4 Q15233,P11047,O95630 3 +Constriction of peripheral visual field 0.2918938787402488 0.0440905820646665 0.9648321999094164 1.0 1.0 18 Q9H061,P40855,Q15555 3 +Anal atresia 0.3044045434953408 0.0433859360397925 0.965393888559742 1.0 1.0 32 Q5SZK8,Q8TAA9,P21964,Q9H9S5 4 +Abnormality of upper limb joint 0.2813746613722655 0.0433069461235023 0.9654568542130756 1.0 1.0 114 Q15392,O75844,Q7LGA3,Q96J02,O95831,Q9Y619,Q8IZA0,Q13510,P10644,Q15042,P16278,Q04656,Q7RTS9,P23786,P50402,P42892,Q9BV10,P16435,P48651,Q8WVQ1,P07196,O95202,Q9Y4P3 23 +Abnormal liver morphology 0.3535868239749349 0.0429279799445685 0.9657589445335356 1.0 1.0 226 Q9HC07,P61916,Q16625,P09601,P39210,Q9BT22,P10619,P51798,Q7KZN9,Q8N511,P04114,Q9Y6M9,Q99519,P07602,P15260,Q15526,Q96J02,Q96A33,P54802,P04062,Q9NVI7,P56192,O15118,P40855,P04066,P53634,Q9HC21,Q07021,Q5HYI8,Q9Y619,O00754,P15586,Q9Y6B6,P01130,P03886,Q13510,P03915,O75787,P16278,P38571,Q04656,Q01844,P07686,Q15904,Q86Y39,O43676,Q14108,P23786,P10253,Q96HY6,Q9NZJ7,Q14739,P09622,Q6NUQ1,P11717,P08236,P11166,Q5XKP0,P31751 59 +Abnormality of the ureter 0.2938102028257134 0.0404858440205385 0.9677057926242578 1.0 1.0 66 O75844,P21964,Q9UHX1,Q04656,O76024,Q86XL3,Q8TAA9,P16435,Q7LGA3,P23786 10 +Congenital ichthyosiform erythroderma 0.3599250026610674 0.0399355870689886 0.9681444793448042 1.0 1.0 5 P04062 1 +Progressive visual field defects 0.4319895116355251 0.0379970677349368 0.9696900199500842 1.0 1.0 2 P35222 1 +Abnormality of malar bones 0.2900905158503689 0.0354148170070211 0.9717489698604612 1.0 1.0 68 Q9HC07,P10644,Q14739,P98164,P21964,Q15042,Q9Y487,O95831,P16435,O00754,Q8WVQ1,Q9H490 12 +Cone shaped epiphysis 0.3122351391954601 0.0342399066106602 0.9726858443112087 1.0 1.0 10 P10644,O95831 2 +Minimal change glomerulonephritis 0.3027805375232782 0.0340797541209873 0.972813552976977 1.0 1.0 15 Q92621,Q96J84,Q8NFH4,Q8N1F7 4 +Elliptocytosis 0.4068852459016342 0.0333976164365781 0.9733575104119788 1.0 1.0 3 P11171,O60488 2 +Hyperextensibility of the finger joints 0.3630363905724192 0.0333482408387806 0.9733968845065362 1.0 1.0 4 Q9Y263,P48651 2 +Abnormality of hand joint mobility 0.3630363905724192 0.0333482408387806 0.9733968845065362 1.0 1.0 4 Q9Y263,P48651 2 +Abnormal nasolacrimal system morphology 0.3056595449323299 0.0332642163729407 0.9734638891559396 1.0 1.0 14 P53701,Q5SZK8,Q6NUK1 3 +Congenital hepatic fibrosis 0.4195345788266075 0.0329690773540079 0.9736992469263102 1.0 1.0 2 Q10713 1 +Neonatal breathing dysregulation 0.4195345788266075 0.0329690773540079 0.9736992469263102 1.0 1.0 2 Q10713 1 +Corticospinal tract hypoplasia 0.4188790560471903 0.0327329390277922 0.9738875564124164 1.0 1.0 2 Q13045 1 +Renal cortical microcysts 0.4156014421501087 0.0315923696744007 0.9747971284718588 1.0 1.0 2 Q6PGP7 1 +Abnormal lung development 0.3087101397046084 0.0314100598270184 0.974942518529062 1.0 1.0 47 O75844,P21964,Q9UHX1,Q5SZK8,Q6NUK1,Q8TAA9,O95202 7 +Abnormal enzyme coenzyme activity 0.3271495715311483 0.0306117506841749 0.975579170851669 1.0 1.0 182 Q9HC07,Q13501,Q16625,P61916,P39210,P10619,P51798,Q8N511,P07602,Q9H9S5,Q96A33,P04062,P56192,O15118,P40855,Q5HYI8,Q9Y619,O00754,Q9Y6B6,P03886,Q13510,O75787,P01889,Q96JJ3,P16278,P38571,P07686,Q15904,Q92643,P23786,O43505,P10253,Q9NZJ7,Q14739,P12235,Q9BV10,P09622,P15529,Q5XKP0 39 +Total anomalous pulmonary venous return 0.4016393442622955 0.0286728061042957 0.9771255450326446 1.0 1.0 3 Q15392,P62244 2 +Eversion of lateral third of lower eyelids 0.4015077023926439 0.0273964015900536 0.9781435682881068 1.0 1.0 2 P61978 1 +Fibrous tissue neoplasm 0.2886981294528971 0.0269427368365089 0.9785054068110152 1.0 1.0 22 P10644,Q07954 2 +Flat occiput 0.3042443439938035 0.0268582278044343 0.9785728108705232 1.0 1.0 14 O00754 1 +Decreased activity of mitochondrial complex i 0.2986328901844441 0.0266043719546143 0.9787752861796752 1.0 1.0 29 Q70HW3,Q9UBX3,Q9Y6M9,Q86Y39,O43676 5 +Squamous cell carcinoma 0.3041214952223021 0.0263048856640871 0.9790141580646085 1.0 1.0 14 Q92889,P53634,P14324,Q9H4L7 4 +Lipodystrophy 0.3049607442246376 0.0256453815366862 0.9795401887277468 1.0 1.0 36 O75844,P42167,Q9Y487,P04066,Q6NUK1,Q14126,P31751 7 +Abnormal blood gas level 0.3940983606557339 0.0224036075961932 0.9821260026295436 1.0 1.0 3 A5YKK6,P06753 2 +Nuclear cataract 0.3558476600749659 0.0223497194940045 0.9821689883511392 1.0 1.0 4 O76024,P08670 2 +Central nervous system cyst 0.304800913739099 0.0215133258379881 0.9828361734420488 1.0 1.0 54 Q9UHX1,Q9Y487,O95202,P23786,P14543,O43505,Q9H9S5 7 +Hyperaldosteronism 0.3680760406424012 0.0211195077017946 0.9831503234692872 1.0 1.0 2 Q01968 1 +Abnormal 2nd finger morphology 0.3394789908835599 0.0208786437438827 0.9833424627344456 1.0 1.0 6 Q8WVQ1 1 +Spontaneous abortion 0.3621763356276513 0.0204195004920801 0.9837087279498684 1.0 1.0 2 P50570 1 +Abnormality of the breast 0.2727726011790058 0.020107478820324 0.9839576341165852 1.0 1.0 105 P10644,P51809,P16870,P10586,Q9BV10,Q5SZK8,Q15555,Q6NUK1,P23786,Q5HYI8,Q9Y619,Q2TAA5,Q7LGA3,O95202,Q96A33,P31751 16 +Pace of progression 0.3095091715687144 0.0200529724014488 0.9840011151796628 1.0 1.0 156 Q13501,P39210,P05023,Q8IV08,Q9Y6M9,O95470,Q9P0J0,Q15526,Q15043,P54802,P04062,P56192,O00584,P98155,Q8NHS3,Q99720,O95831,Q16637,P15586,P07942,Q13510,O14979,O75787,Q9NR28,Q04656,Q14108,P27544,P50402,P12235,O14773,O60313,P07196,Q5XKP0,O00400 34 +Retinal fold 0.3556211078334892 0.0197507394679561 0.9842422144176576 1.0 1.0 2 P35222 1 +Delirium 0.3493936414290304 0.019209816531378 0.9846737265889244 1.0 1.0 2 Q9UJS0 1 +Portal vein thrombosis 0.3398885611274895 0.0185370800728834 0.98521039702112 1.0 1.0 2 P35222 1 +Delayed ossification of carpal bones 0.3333333333333264 0.0181651319397626 0.9855071187255804 1.0 1.0 2 Q9NUQ7 1 +Edema of the dorsum of hands 0.3277613897082828 0.0178992376053691 0.985719237220178 1.0 1.0 2 Q9Y263 1 +Edema of the dorsum of feet 0.3277613897082828 0.0178992376053691 0.985719237220178 1.0 1.0 2 Q9Y263 1 +Intestinal malrotation 0.2960106953479466 0.0178956932238091 0.985722064774606 1.0 1.0 28 Q14739,P98164,P21964,Q9BV10,O95202 5 +Abnormality of peripheral nerves 0.3067657411215712 0.0173400735896857 0.9861653163009332 1.0 1.0 43 P39210,Q6DD88,Q99720,O95831,Q99519,Q9Y619,P07602,O15269,P07196,Q9NZJ7 10 +Nausea and vomiting 0.2981665419825704 0.0155583285635748 0.987586750644387 1.0 1.0 140 Q13501,P39210,Q9Y6M9,O00592,P07602,Q2TAA5,Q13277,P06280,Q68CQ7,Q5HYI8,Q9NZ08,Q9Y619,Q8IZA0,Q9Y6B6,P03886,P03915,Q13423,P01889,P38571,Q04656,Q01844,O96000,P00533,P00403,Q86Y39,P11117,O43676,P23786,Q9NZJ7,P35637,P42892,Q15165,P09622,P22695,P15529,Q9Y4P3 36 +Proximal muscle weakness in lower limbs 0.2949804754999648 0.0138431681283788 0.98895510264059 1.0 1.0 16 Q16637,P12235,P50402 3 +Limb joint contracture 0.2675689428300366 0.0127078130664123 0.9898609050447028 1.0 1.0 99 O75844,Q7LGA3,Q9H9S5,Q99720,Q9HC21,Q9Y619,Q8IZA0,Q15042,P23786,P50402,P35637,P42892,Q86XL3,P16435,P48651,O60313,Q8WVQ1,P07196,P36543 19 +Polymicrogyria 0.2841823922707796 0.0098593983239963 0.9921334657466808 1.0 1.0 70 Q15392,Q96N66,Q16625,P55011,Q9NP72,Q9H9S5,P40855,P42345,Q9Y5P6,Q01105,Q9Y320,Q15042,P67870,P23786,O43505,O75381,Q96C86,Q9Y487,Q9NZ01,P36543 20 +Abnormality of the sense of smell 0.2873864011969499 0.0097889141948415 0.9921897012312808 1.0 1.0 23 P04062,O00592,Q04656 3 +Abnormal cellular phenotype 0.3242580729764473 0.0093376883308686 0.9925497109154948 1.0 1.0 180 O75844,Q13501,P09601,Q70HW3,P51798,Q7KZN9,Q9Y6M9,Q9P0J0,P07602,P15260,Q15526,Q96J02,P04062,P02786,O00754,P15586,P03886,Q13510,P03915,Q9BXW9,O75787,O96000,P00403,Q15904,Q86Y39,O43676,Q14108,Q92643,Q9Y2R0,P23786,Q9NZJ7,Q14739,P12235,P21964,P35637,Q9BV10,O75503,P09622,Q9UBX3,O14773,P11166,P13073 42 +Abnormality of the peritoneum 0.2820519079691751 0.0092836098324116 0.9925928574442922 1.0 1.0 20 Q8N1F7,Q92621,Q01844,Q8NFH4,Q5HYI8 5 +Weakness due to upper motor neuron dysfunction 0.2912270380105912 0.0085153503381375 0.99320581554454 1.0 1.0 131 Q13501,Q7KZN9,Q96CU9,Q9P0J0,P07602,Q15526,Q9H9S5,P04062,P56192,O95831,Q9NZ08,Q9Y619,O00754,P07942,P03886,Q13510,P03915,O75787,Q13423,P01889,Q7RTS9,P00403,P17900,Q6DKK2,Q9NZJ7,P35637,Q9UBX3,P11166,O60313,Q5XKP0,O00400 31 +Paralysis 0.3045283265545812 0.0065892043484142 0.9947426136263148 1.0 1.0 51 P50402,P04062,Q13501,P35637,Q15165,Q9HC21,P51798,Q68CQ7,P11166,P17900,P10253 11 +Head tremor 0.3012469362834488 0.0038816679700487 0.9969028848340882 1.0 1.0 13 Q99720,P35637 2 +Midface retrusion 0.2566138989849963 0.0038112571461137 0.996959064127812 1.0 1.0 86 Q9HC07,P10644,Q14739,P98164,Q15042,Q9BV10,Q9Y487,Q6NUK1,O95831,P16435,P53701,O00754,Q8WVQ1,Q96J02,Q96A33 15 +Male hypogonadism 0.3284128367950717 0.0037046272812414 0.9970441418499324 1.0 1.0 7 O76024,Q92889 2 +Broad thumb 0.2894465899665551 0.0034712977873637 0.9972303106519316 1.0 1.0 25 Q7LGA3 1 +Simplified gyral pattern 0.2922625695955798 0.0031249807089945 0.997506630197656 1.0 1.0 27 P98155,Q5KU26 2 +Polydactyly 0.3034090475992096 0.0029971952741043 0.9976085877454955 1.0 1.0 39 Q8N3U4,Q9BXW9,Q14739,P17612,Q9UHX1,P54198,Q15067,P21964,O43924,O60826,O95155,Q99519,Q9UBM7,O95202,O75419 15 +Alacrima 0.342191601049868 0.0027301329041687 0.997821671812898 1.0 1.0 5 Q9NRG9,Q7Z392,P55011,Q96IJ6 4 +Optic atrophy 0.3230758010408266 0.00216990071971 0.99826867107592 1.0 1.0 179 Q8TCJ2,P51572,P51798,Q7KZN9,Q96CU9,Q92889,Q9P0J0,Q99519,P07602,Q9H6K4,Q15526,Q15043,Q9NP72,Q9H9S5,Q96PU5,O95630,Q9NVI7,P40855,Q9BTW9,Q15067,Q8NHS3,Q9HC21,P06280,Q9Y5P6,P50897,Q9BPX6,Q9H490,P07942,P03886,P03915,P10644,P04350,P01889,Q15042,P16278,Q6PJG6,P00403,Q86Y39,P49815,Q9H2C2,O43505,O95169,Q9NZJ7,O75381,P21964,Q3ZCQ8,Q15555,O60826,O00429,O43292,O76024,Q9H061,O60313,Q5KU26,O95202,Q5XKP0 56 +Abnormal facial expression 0.2979298611599877 0.0015053916753825 0.998798871677918 1.0 1.0 32 P04062,O75787,P12235,Q04656,O00592,Q9H9S5 6 +Anteverted ears 0.3590163934426187 0.00052171457431 0.999583732014896 1.0 1.0 3 Q6W2J9,P27635 2 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5fa796bd843a3c7b8605b6cbd1b35d67155edc17 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowman capsule morphology", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal coccyx morphology", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal endothelium morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal descemet membrane morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal haptoglobin level", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal perifollicular morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of olfactory lobe morphology", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of venous physiology", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Achilles tendon contracture", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical adenoma", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal fissure", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior chamber synechiae", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior synechiae of the anterior chamber", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Anuria", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanges of the toes", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hallux", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Budd chiari syndrome", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac rhabdomyoma", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central opacification of the cornea", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 2nd finger", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Conjunctival icterus", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crossed fused renal ectopia", "Crumpled long bones", "Cryptophthalmos", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular hemoglobin concentration", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased thyroid stimulating hormone level", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Exudative retinal detachment", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Helicobacter pylori infection", "Hemangioblastoma", "Hemangiomatosis", "Hematochezia", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemolytic uremic syndrome", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the primary teeth", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic iris stroma", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired renal concentrating ability", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal bleeding", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular iliac crest", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct aplasia", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limbal dermoid", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microangiopathic hemolytic anemia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thymus", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncommunicating hydrocephalus", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuchal rigidity", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic endocrine tumor", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid hyperplasia", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Photosensitive tonic clonic seizure", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Placental abruption", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posterior uveitis", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged pr interval", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent coccyx", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Reflex seizure", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal angiomyolipoma", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal nonattachment", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rhizomelic arm shortening", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shortening of all phalanges of the toes", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowed slurred speech", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue neoplasm", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous lipoma", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Thinning of descemet membrane", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thrombophlebitis", "Thymus hyperplasia", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Wide pubic symphysis", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced primary teeth", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AKT1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG12", "ALG2", "ANAPC1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO10", "ANO6", "ANXA11", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APOB", "APOL2", "APP", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARPC1B", "ARV1", "ASAH1", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATG7", "ATIC", "ATL3", "ATP1A1", "ATP2A2", "ATP5A1", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATXN10", "AURKA", "B3GALT6", "B4GAT1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCL10", "BCOR", "BCS1L", "BLVRA", "BMS1", "BRAT1", "BRCA1", "BRD4", "BUB1B", "BUB3", "C19orf70", "C1QBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CAP2", "CAPN1", "CAPN5", "CARS", "CAST", "CBFB", "CBL", "CCDC22", "CCDC47", "CCT5", "CD2AP", "CD320", "CD3EAP", "CD46", "CDC40", "CDC42", "CDC45", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CELF2", "CEP290", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHEK2", "CHMP1A", "CHMP2B", "CHORDC1", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN7", "CLIP1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNOT1", "CNP", "COA3", "COA7", "COG7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COX15", "COX2", "COX4I1", "COX5A", "CPE", "CPNE1", "CPOX", "CPSF1", "CPT2", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSB", "CTSC", "CUL3", "CUL4B", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DKC1", "DLAT", "DLD", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJC13", "DNAJC21", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DYM", "DYNC1H1", "DYNC1I2", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGFR", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "ELP4", "EMC1", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOSC2", "EXOSC3", "EXOSC9", "EZR", "FAH", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FDFT1", "FDPS", "FDXR", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXC1", "FOXRED1", "FREM2", "FRG1", "FSCN1", "FTO", "FTSJ1", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATB", "GATC", "GBA", "GCDH", "GDAP1", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GINS1", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNAI2", "GNAI3", "GNPAT", "GNS", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GUSB", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIRA", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP2", "IGF2R", "IKBKB", "IMPAD1", "IMPDH1", "INF2", "IRS4", "ISCU", "ITCH", "ITM2B", "ITPA", "IVD", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIAA0319L", "KIF11", "KIF1A", "KIF1B", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "KIRREL1", "KMT2A", "LAMB1", "LAMC1", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LEMD2", "LEMD3", "LETM1", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LSS", "LZTFL1", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MANBA", "MAP1B", "MAP2K1", "MAPK1", "MAPRE2", "MARS", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MECR", "MED12", "MED17", "MESD", "MFSD8", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MOGS", "MORC2", "MPG", "MPI", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBN", "NCAPD2", "NCAPH", "NCDN", "NCSTN", "ND1", "ND5", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NEU1", "NF1", "NFS1", "NHLRC2", "NHP2", "NID1", "NIPBL", "NNT", "NONO", "NOP10", "NOP56", "NOVA2", "NPC1", "NPC2", "NPM1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NT5C2", "NTHL1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDXK", "PEPD", "PEX14", "PEX19", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PHKA1", "PICALM", "PIGA", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PISD", "PITRM1", "PKN1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPT1", "PODXL", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PSPH", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRICH1", "QRSL1", "RAB18", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RABL3", "RAC1", "RAD21", "RAD50", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RIPK1", "RNASEH2A", "RNASET2", "RNF2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS28", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RREB1", "SALL2", "SAMHD1", "SAR1B", "SARS", "SARS2", "SASS6", "SBDS", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SDHA", "SDHB", "SEC23A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEPT9", "SERPINB6", "SERPINB8", "SERPINH1", "SET", "SETD1A", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC2A1", "SLC33A1", "SLC39A14", "SLC9A6", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SORL1", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD7", "STAT1", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "STX3", "SUCLA2", "SUCLG1", "SURF1", "SUZ12", "SYNE2", "TACO1", "TAF15", "TAF6", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TCOF1", "TDP2", "TECR", "TELO2", "TENM3", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM50", "TIMMDC1", "TJP2", "TKT", "TLK2", "TMCO1", "TMEM126A", "TMEM165", "TMEM199", "TMEM43", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOR1AIP1", "TP53", "TPI1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRRAP", "TSC2", "TSFM", "TSR2", "TTC19", "TTC37", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "UBA1", "UBA5", "UBE4A", "UBE4B", "UBTF", "UFC1", "UFD1", "UFSP2", "UGP2", "UMPS", "UNC45A", "UNG", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP7", "USP8", "USP9X", "VAC14", "VAMP7", "VANGL1", "VAPB", "VARS1", "VCL", "VCP", "VIM", "VLDLR", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WBP11", "WDR1", "WDR36", "WDR4", "WDR73", "WFS1", "WIPI2", "XPC", "XPNPEP3", "XRCC1", "YARS", "YARS2", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZNF687"], "leading_proteins": ["AAAS", "ABCD3", "ABCD4", "ACBD5", "ACOX1", "ACP2", "ACSL4", "ACTN1", "AGK", "AIFM1", "AKT1", "AKT2", "ALDH18A1", "ALDH3A2", "ALG1", "ALG11", "ALG12", "ALG2", "ANKLE2", "ANO10", "ANO6", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "APC", "APOB", "APOL2", "APP", "ARL2", "ARV1", "ASAH1", "ATAD3A", "ATL3", "ATP1A1", "ATP2A2", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATXN10", "B3GALT6", "B4GAT1", "BCAP31", "BCOR", "BRAT1", "C19orf70", "C1QBP", "CALM3", "CALR", "CANT1", "CAPN5", "CARS", "CCDC22", "CCDC47", "CD46", "CDC40", "CDC45", "CDH2", "CDK4", "CEP290", "CERS1", "CHMP2B", "CLCC1", "CLCN7", "CLN5", "CLPP", "CNOT1", "COA3", "COA7", "COLEC12", "COMT", "COPB2", "COX15", "COX2", "COX4I1", "CPE", "CPOX", "CPT2", "CRTAP", "CSNK2B", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSB", "CTSC", "CYB5R3", "DARS2", "DCPS", "DDB1", "DDRGK1", "DDX41", "DHCR24", "DHCR7", "DHFR", "DIABLO", "DLD", "DLG3", "DNM1L", "DNM2", "DPM1", "DSC2", "DSC3", "DSG2", "DYM", "ECE1", "EGFR", "EIF2B5", "ELMO2", "EMD", "EPB41", "ERAP1", "ERCC2", "ERCC4", "ERGIC1", "EWSR1", "EXOC7", "EXOSC3", "FANCD2", "FAR1", "FARSA", "FDPS", "FKBP14", "FKRP", "FLII", "FOXRED1", "FREM2", "FUCA1", "FUS", "G6PD", "GAA", "GALNT2", "GBA", "GGCX", "GLA", "GLB1", "GLMN", "GLT8D1", "GM2A", "GMPPA", "GMPPB", "GNAI2", "GNAI3", "GNS", "GPAA1", "GPD2", "GUSB", "HCCS", "HEXA", "HEXB", "HIRA", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HPS6", "HS2ST1", "HSD17B4", "HTT", "IARS2", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP2", "IGF2R", "IMPAD1", "IRS4", "ITCH", "ITM2B", "KDSR", "KEAP1", "KIAA0319L", "KIF23", "KIFBP", "KIRREL1", "LAMB1", "LAMC1", "LBR", "LDLR", "LETM1", "LIPA", "LMAN1", "LRP1", "LRP2", "MAGT1", "MAN2B1", "MANBA", "MAP2K1", "MAPK1", "MAPRE2", "MARS", "MATR3", "MBOAT7", "MCM6", "MED17", "MESD", "MFSD8", 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1.5419829368340558e-29 +Calcium signaling pathway 11 16 3.0019577332214 0.0026824941790373 5.735436893203883 16.946601941747574 1.0005800740695592 0.3113014190776675 2.984654368989517 2.3866666657890168 1.2450167285670062 0.3187454651207294 0.0002591159261027 1.0 1.0 0.0203556588144228 0.0002609651056342 +Cell adhesion molecules cams 11 13 2.991327845914966 0.0027776710616469 4.043689320388349 9.91019417475728 0.3640395302172229 0.4325707543794381 2.3114392567097153 2.512916721209252 1.1817978240178808 0.3174557953274378 0.0002828884783443 1.0 1.0 0.0003015006992345 4.524440963497809e-05 +Other glycan degradation 8 9 2.963568005414778 0.003040948601237 3.966019417475728 7.12378640776699 0.0449593300314452 0.158186848086018 1.7909726921672984 0.8075596903062239 1.9584092358200416 0.2320333335657103 1.6429826451855105e-08 0.0652597674910206 1.3836932757398312e-07 2.80712260492779e-10 2.246895762258043e-09 +Snare interactions in vesicular transport 8 13 2.9034494914737734 0.003690764983212 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 7.432523468103786e-06 0.1553991536419083 0.2872333566147377 1.693641470299462e-05 3.170481154810999e-05 +Sphingolipid metabolism 9 13 2.8384968273667446 0.0045326569980954 5.672330097087379 11.759708737864075 0.9805985471070467 0.1821702203806468 2.452838935293596 1.3449033287601222 1.7625559835482287 0.2542774311591588 3.990390837107398e-06 0.1135912525516411 0.0237627189197599 0.0002861885476851 1.1237436337996233e-07 +Glycosaminoglycan degradation 6 7 2.7378280277947264 0.0061846407359877 3.407766990291262 5.864077669902913 0.1350713234786387 0.1703873780123549 1.3379225542760151 0.7043353086258667 1.932540087143412 0.2532951180616937 1.1299958364989336e-07 1.0 0.0056684159955205 3.213939723308515e-09 3.903860956515125e-07 +Antigen processing and presentation 7 18 2.568413658527497 0.0102165159675478 5.337378640776699 16.74757281553398 0.2387870946403815 0.5680791453500826 2.8523982282892524 1.5499354612429144 0.9338462051385796 0.3189030666688743 0.0008496078188353 0.1715759324473242 0.3143397790261298 0.0023536569339089 0.0004730993907641 +Cardiac muscle contraction 9 18 2.5397786141386693 0.0110922657192034 7.728155339805825 19.856796116504853 1.0644813600437804 0.240240383706381 3.4195161605095614 1.765741250102918 1.6465694074711887 0.3002212677564749 0.0020343441612113 0.1952735388158895 0.0693457394610891 0.0044406378118471 4.558635539447923e-05 +Vibrio cholerae infection 6 19 2.187738957360351 0.028688622602307 4.266990291262136 20.3495145631068 0.719353425420958 0.4383869162647907 2.394690257024947 1.7733668152523894 0.9402989147235556 0.3258958759345889 0.0008496078188353 0.01497108596825 0.0538434207197609 0.0142235096743441 0.0024204837857025 +Natural killer cell mediated cytotoxicity 3 15 2.120215959389047 0.0339878371304869 4.859223300970874 15.269417475728156 0.0010910938828692 0.6578096713542636 2.9270395558972484 2.707009357328761 0.724843022952491 0.2863674189596557 0.2782501333142744 0.2731012734555347 0.4724360815693985 0.2146915796551673 0.3996311858230128 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..acdfad71ac572483c290601dbc0554868d0f083d --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 179, + "title": "Average number of proteins per term", + "value": 16.368715083798882 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..963d42eae81f484dfa2bd04ed18fa603a55f58b4 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f83281b23c85158d3fa09a22b68da968a938de34 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,77 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Lysosome 0.8421265339501762 4.557507055536889 5.1764352084759935e-06 0.0009261551538453 0.0009265819023173 55 P61916,P10619,Q9UMR5,Q99519,P07602,P07858,P54802,P04062,Q15012,O15118,Q8NCC3,Q93050,Q8NHS3,P04066,P53634,P06280,P50897,O00754,P15586,P20645,Q13510,O00115,P16278,P38571,P06865,Q99538,Q99523,P07686,Q15904,P11117,Q14108,P17900,P10253,Q9NZJ7,O00462,O75503,P11717,P08236,O14773,P11279 40 +Calcium signaling pathway 0.7771598949057235 3.0019577332214 0.0026824941790373 0.3817186300503669 0.0660646931994962 16 P12235,P20020,P45880,P12236,P16615,P05141,P00533,P21796,Q9Y277,P0DP25,P46020 11 +Cell adhesion molecules cams 0.8313077877616114 2.991327845914966 0.0027776710616469 0.3921912088878188 0.0660646931994962 13 Q9Y624,P06756,P19022,P10321,P10586,P01889,Q16625,P04439,Q92896,Q92692,Q5ZPR3 11 +Other glycan degradation 0.907687253613658 2.963568005414778 0.003040948601237 0.4202504742092904 0.0660646931994962 9 O00462,P16278,P06865,P04066,P07686,Q99519,Q9BTY2,O00754 8 +Snare interactions in vesicular transport 0.8139813902862456 2.9034494914737734 0.003690764983212 0.4841138030265542 0.0660646931994962 13 O95249,Q13190,Q9P2W9,O60499,O15400,Q86Y82,Q13277,Q9UNK0 8 +Sphingolipid metabolism 0.8012969770699399 2.8384968273667446 0.0045326569980954 0.5565587493943464 0.0737586911508262 13 P04062,P16278,P06280,Q8TCT0,O95470,Q99519,O15269,Q16739,Q13510 9 +Glycosaminoglycan degradation 0.9228496388706512 2.7378280277947264 0.0061846407359877 0.6706018994855916 0.0922542243118178 7 P54802,P16278,P06865,P07686,P15586,Q9Y251 6 +Antigen processing and presentation 0.6643744564807833 2.5684136585274975 0.0102165159675478 0.8408904365606255 0.1075739034230033 18 P61289,P01889,P10321,Q99538,Q03518,P04439,P07858 7 +Cardiac muscle contraction 0.6598069177100052 2.5397786141386693 0.0110922657192034 0.8642050989266523 0.1103064202076339 18 P54709,O14949,P14406,P05023,P16615,P00403,Q9UDW1,Q92581,P13073 9 +Vibrio cholerae infection 0.5876620997784137 2.187738957360351 0.028688622602307 0.9945403201509606 0.1901949424375173 19 O43731,P24390,Q9Y487,Q93050,Q15904,P36543 6 +Natural killer cell mediated cytotoxicity 0.6406872256087024 2.120215959389047 0.0339878371304869 0.9979493835950995 0.2097869947019709 15 P04439,P10321,P15260 3 +Renin angiotensin system 0.8825944629497979 1.9446749530379632 0.0518141119289048 0.9999268971610904 0.2622388986715609 4 Q9UIQ6 1 +Small cell lung cancer 0.6467488003968639 1.9371050566566328 0.0527325026359348 0.9999385386842607 0.2622388986715609 12 P07942,P06756,P31751 3 +Cytokine cytokine receptor interaction 0.8065516286339577 1.864056045243796 0.0623138342615352 0.9999900392039752 0.2632800467047091 5 P36896,P15260 2 +Type i diabetes mellitus 0.7429981049878112 1.8236292940046093 0.068208134787848 0.9999967782953966 0.2632800467047091 6 P04439,P10321,P16870 3 +Ecm receptor interaction 0.7210533220790986 1.8199053349357288 0.0687734223495142 0.999997109919902 0.2632800467047091 7 Q7L0J3,P07942,P06756,Q08722 4 +Autoimmune thyroid disease 0.851358453146788 1.8175731551358516 0.069129397738108 0.9999973010962044 0.2632800467047091 4 P04439,P10321 2 +Allograft rejection 0.851358453146788 1.8175731551358516 0.069129397738108 0.9999973010962044 0.2632800467047091 4 P04439,P10321 2 +Graft versus host disease 0.851358453146788 1.8175731551358516 0.069129397738108 0.9999973010962044 0.2632800467047091 4 P04439,P10321 2 +Glycosphingolipid biosynthesis ganglio series 0.8343719252213722 1.747872378036836 0.0804861288124014 0.99999970012999 0.2962225875574962 4 P16278,P06865,P07686 3 +Glycosphingolipid biosynthesis globo series 0.9327868852458968 1.715811307348588 0.0861965839405818 0.99999990167881 0.3000234103689222 3 P06865,P06280 2 +Glioma 0.5945023193692693 1.7000401522320248 0.0891233732140934 0.9999999446317356 0.3010015812325043 13 P31751,P0DP25,P42345,P00533 4 +Endocytosis 0.4870302890020659 1.68881744369244 0.0912544199079932 0.9999999635939324 0.3016616452166201 52 O43633,P20339,Q96J02,P51148,Q96PU5,P02786,P61020,P10321,P08069,P01130,Q9H9H4,P01889,P00533,Q9H223,Q8WUM4,P04439,O00429,Q9H4M9,Q96CW1 19 +Dilated cardiomyopathy 0.6841103791365741 1.6412331066995225 0.1007490358404898 0.99999999444501 0.3016616452166201 7 P05556,P16615,P06756,P50402 4 +O glycan biosynthesis 0.8081338143653544 1.6394689348657658 0.1011156352681408 0.9999999948360156 0.3016616452166201 4 Q10472,O43505,Q10471 3 +Glycerophospholipid metabolism 0.5590391291913233 1.6201762459406983 0.1051944225435264 0.9999999977121152 0.3086852727096922 15 Q8NF37,Q96N66,Q8NCC3,Q9UG56,P48651,O14735,P35790 7 +Parkinsons disease 0.4752988404743426 1.6031696056883642 0.1088972139128285 0.999999998910878 0.3087888518933935 53 O14949,P13073,P12235,P45880,P12236,P14406,P05141,O96000,Q9Y6M9,P00403,Q9UDW1,O43676,P21796,Q9Y277,P03886,O75438,O95169,P03915 18 +Hypertrophic cardiomyopathy hcm 0.6759541972552163 1.6013797326024977 0.1092928389130438 0.9999999989940996 0.3087888518933935 7 P16615,P06756,P50402 3 +Aldosterone regulated sodium reabsorption 0.6887058775351238 1.5680143211550048 0.1168777901686048 0.9999999997823672 0.3218634529258504 6 P54709,P05023,Q96PU5 3 +Oxidative phosphorylation 0.4597532447855864 1.548071844934661 0.1216049998906416 0.9999999999167308 0.3248849997078337 57 O75964,P14406,Q9Y6M9,Q7KZN9,Q93050,Q9UDW1,P03886,O75438,P03915,O14949,O96000,P00403,Q15904,Q86Y39,O43676,O95169,Q9Y487,P13073,P36543 19 +Huntingtons disease 0.3889879041741704 1.456308954578282 0.1453072312329888 0.9999999999993776 0.3747275316588627 76 O14949,P13073,P12235,P45880,P12236,P14406,P05141,O96000,Q9Y6M9,P00403,P22695,Q9UDW1,O43676,P21796,Q9Y277,O75438,O95169 17 +Galactose metabolism 0.5407049822050749 1.3790817821010002 0.1678695401313628 0.9999999999999948 0.403409396861822 13 P16278,P10253,P06280 3 +Melanogenesis 0.5597376038702618 1.3498776258756022 0.1770552396558293 0.9999999999999992 0.403409396861822 10 P35222,P17612,P08754,P04899,P0DP25,P63096 6 +Porphyrin and chlorophyll metabolism 0.5261291705251319 1.3472520715321408 0.1778990625555321 0.9999999999999994 0.403409396861822 14 P08236,P30519,P09601,Q7KZN9 4 +Jak stat signaling pathway 0.5800445841012973 1.3425239865790086 0.1794261583275274 0.9999999999999996 0.403409396861822 9 P15260 1 +Protein export 0.5110594800846496 1.31466252428858 0.1886233467309044 1.0 0.403409396861822 15 Q9Y5M8,Q15005,P67812,Q15070 4 +Non small cell lung cancer 0.5498438310441198 1.294319359190912 0.1955551322183242 1.0 0.4118161019656474 10 P31751 1 +Pancreatic cancer 0.4955035832965925 1.2812319284125124 0.2001122145468352 1.0 0.4165126326032966 16 P11233,P31751 2 +Amyotrophic lateral sclerosis als 0.5282007946290102 1.2097707645233398 0.2263668673956171 1.0 0.4596390604851798 11 P07196,P20339,Q9BUN8 3 +Gap junction 0.4716089052535758 1.1925152006661366 0.2330592940813141 1.0 0.4596390604851798 17 P17612,P04350,P08754,P00533,P04899,Q9BUF5 6 +Starch and sucrose metabolism 0.5097895116677195 1.1909549922110498 0.233671254213136 1.0 0.4596390604851798 13 P52789,P10253,P08236 3 +Endometrial cancer 0.5123068185260478 1.1587643370581524 0.2465522579456167 1.0 0.4768615135069374 12 P31751 1 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.6019562730648029 1.1493325154251055 0.250418895361185 1.0 0.4768615135069374 6 Q9H490,Q92643 2 +Hedgehog signaling pathway 0.7672131147540877 1.0577018554415096 0.2901913890927239 1.0 0.5342859566474859 3 P98164,P17612 2 +Viral myocarditis 0.49527296622726 1.0570084527668346 0.2905077297237612 1.0 0.5342859566474859 12 P04439,P10321 2 +Epithelial cell signaling in helicobacter pylori infection 0.432464734188501 1.0503177479053083 0.2935720479844457 1.0 0.5342859566474859 23 Q9Y624,Q9Y487,Q93050,P00533,Q15904 5 +Alzheimers disease 0.4081362489531038 1.046134503846057 0.295498936916766 1.0 0.5342859566474859 57 O14949,P13073,P14406,P16615,Q92542,O96000,Q9Y6M9,P00403,Q07954,O75438,Q9UDW1,O43676,P0DP25,P05067,O95169 15 +Long term depression 0.4915815543456365 0.996661631569404 0.3189287794056759 1.0 0.5660152101921337 11 Q14344,P08754,P08069,P04899,P30154 5 +Steroid hormone biosynthesis 0.8151425762045383 0.9917948351537618 0.3212976176588418 1.0 0.5660152101921337 2 P21964 1 +Apoptosis 0.419653499041479 0.9779649807263662 0.3280916444383959 1.0 0.5701786830531346 19 P10644,O94919,P31751 3 +Prostate cancer 0.437614539537291 0.9561248926505604 0.3390091398669881 1.0 0.5834868849633738 17 P31751,P42345,P00533 3 +Melanoma 0.4877760001532101 0.942354094441188 0.3460113815330734 1.0 0.5898670218516204 10 P31751,P00533 2 +N glycan biosynthesis 0.4313489431974208 0.9124522257267674 0.3615307077581704 1.0 0.604803707371145 17 Q9BV10,P04843,Q9BT22,Q16706,P26572,Q2TAA5,P33908,P46977 8 +Olfactory transduction 0.7244371791702184 0.8907625153776108 0.3730565887174113 1.0 0.617706693231713 3 P0DP25 1 +Vasopressin regulated water reabsorption 0.451352975402945 0.8756999956087071 0.3811931477460342 1.0 0.6203052131503647 14 P20339,P51148,P61020,Q13561 4 +Steroid biosynthesis 0.4741261317659648 0.8647057530268675 0.3872003110293269 1.0 0.6244041051734192 10 Q15392,P38571,Q15800,Q16850,Q14534 5 +Proximal tubule bicarbonate reclamation 0.5134430542652217 0.7893976051141973 0.4298796551962662 1.0 0.6521811843356163 7 P05023,Q9UBX3 2 +Alpha linolenic acid metabolism 0.7554900032776108 0.7593215982700555 0.4476602005140604 1.0 0.6622411230745191 2 Q15067 1 +Type ii diabetes mellitus 0.4505011049758866 0.7308845290072881 0.4648496865733351 1.0 0.671033015295379 10 P52789,P14672,O14654 3 +Axon guidance 0.3905294529145681 0.7124985147742419 0.476156130830657 1.0 0.6768053832498717 26 Q15375,O15031,P05556,P04899,O94813,O14786 6 +Abc transporters 0.5428141769652735 0.6872511566462826 0.4919244723105214 1.0 0.6933423664849081 5 Q03518 1 +Arrhythmogenic right ventricular cardiomyopathy arvc 0.4163988901350233 0.6556894793212164 0.5120239394280266 1.0 0.7077860390273621 14 P06756,P19022,P16615,P05556,Q14126,P50402 6 +Adipocytokine signaling pathway 0.4001446222786111 0.6413057256138763 0.5213240699705366 1.0 0.7123435765246264 16 O14654,P11166,P14672,P31751 4 +Nicotinate and nicotinamide metabolism 0.551008022074144 0.5755532097922003 0.5649172152455297 1.0 0.7603021167590212 4 Q13423 1 +Riboflavin metabolism 0.4629442351903816 0.5421956109234278 0.5876837585751229 1.0 0.7792251317403481 7 Q9NPH0,P11117 2 +Progesterone mediated oocyte maturation 0.3579706192766004 0.4637341650898841 0.642838216219082 1.0 0.8219145764515406 26 P30260,Q9UJX4,Q9UJX3,P17612,O95067,P53350,P08754,P08069,P04899,P63096,P31751 11 +Gnrh signaling pathway 0.3905538410010759 0.4182626140174407 0.6757551207356194 1.0 0.8578735220686232 11 P0DP25,P00533 2 +Leukocyte transendothelial migration 0.33243752918029 0.30952842224837 0.7569195951355394 1.0 0.9032573835284105 22 Q9Y624,P04899,P05556,Q16625 4 +Adherens junction 0.3330911676822106 0.2969069208421473 0.7665375722392964 1.0 0.9055597323567076 24 Q9UQB8,P10586,O60716,P00533,P08069,P67870,Q92692 7 +P53 signaling pathway 0.3356367226061304 0.1813137155421368 0.8561213410058655 1.0 0.9823443592310892 14 P11802,O14681,O14757,O95067,P04637,P06493,P42574,P49327,P14635,P31350,P49815,P24941,Q07812 13 +Wnt signaling pathway 0.3075004447805682 0.1235427583483524 0.9016773173400034 1.0 1.0 24 P35222,P17612,P48729,P67870,Q8TAA9,P63208,P30154,Q9BZK7 8 +Folate biosynthesis 0.4033101553217536 0.1099449874432824 0.9124530039619976 1.0 1.0 4 Q92820 1 +Phosphatidylinositol signaling system 0.3303056316551452 0.0671291003738781 0.9464789273919004 1.0 1.0 9 O14735,P0DP25 2 +Acute myeloid leukemia 0.3147224543837154 0.0473583803042481 0.9622275994832924 1.0 1.0 11 P31751 1 +Retinol metabolism 0.379185791376016 0.0117183568129637 0.9906503180043252 1.0 1.0 3 Q6NUM9 1 +Basal cell carcinoma 0.3681967213114719 0.0051867073740246 0.9958616248199206 1.0 1.0 3 P35222,P25054 2 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9df1cf81c63efb8567209048e5a6426ba61c94a2 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Complement and coagulation cascades", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ACVR1B", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALYREF", "ANAPC1", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEX1", "APP", "APRT", "AQR", "ARF6", "ARFGAP1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATG7", "ATIC", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "AURKA", "B3GALT6", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCAT1", "BCAT2", "BCL10", "BDH2", "BIRC6", "BLVRA", "BLVRB", "BPNT1", "BRCA1", "BRD8", "BUB1B", "BUB3", "BUD31", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CASP3", "CBL", "CBR1", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CD276", "CD46", "CD47", "CDC20", "CDC23", "CDC27", "CDC40", "CDC42", "CDC45", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDS2", "CERK", "CETN2", "CFL1", "CFL2", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHORDC1", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT4", "CNOT9", "COMT", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPE", "CPOX", "CPT2", "CRKL", "CRNKL1", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CXADR", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DBT", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH3", "DIS3", "DLAT", "DLD", "DLST", "DNA2", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DPM1", "DPYSL2", "DPYSL5", "DSC2", "DSG2", "DSP", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERCC2", "ERCC3", "ERCC4", "ERO1A", "ESPL1", "EXO1", "EXOC4", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAH", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GCAT", "GCDH", "GFPT1", "GGA2", "GGCT", "GGH", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNPAT", "GNPDA1", "GNS", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPI", "GRB2", "GRHPR", "GSK3A", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADH", "HADHA", "HADHB", "HCCS", "HDAC1", "HDAC2", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IGF1R", "IGF2BP1", "IGF2R", "IKBKB", "ILK", "IMPDH1", "IMPDH2", "IQGAP1", "IQGAP2", "IRS4", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KDELR1", "KDELR3", "KDSR", "KEAP1", "LAMB1", "LAMC1", "LAMP1", "LAP3", "LAPTM4A", "LARS", "LARS2", "LDHA", "LDHB", "LDLR", "LGMN", "LIG1", "LIG3", "LIPA", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LRP1", "LRP2", "LSM2", "LSM3", "LSM6", "LSS", "LTA4H", "LYN", "LYPLA1", "M6PR", "MAD2L1", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MAP2K1", "MAP2K4", "MAPK1", "MAPK3", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MFSD8", "MGAT1", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPG", "MPHOSPH6", "MPI", "MPST", "MPV17", "MRE11", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVB12A", "MYH10", "MYH14", "MYH9", "MYL6", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCBP1", "NCK1", "NCKAP1", "NCL", "NCSTN", "ND1", "ND5", "NDUFA10", "NDUFA11", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEU1", "NF1", "NLN", "NME1", "NME2", "NME3", "NNT", "NPC1", "NPC2", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NT5C2", "NTHL1", "NUDT5", "NUDT9", "OAT", "OCLN", "OCRL", "OGDH", "ORC3", "ORC5", "OXA1L", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK2", "PANK4", 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1.1708540815039898 0.1757583754913391 4.192861933829232 2.1968580551223003 2.1941615995620167 0.2567064655985949 2.1214966321541079e-10 0.0356328568827733 2.690584339783567e-05 2.30996546554735e-08 4.7437155331330864e-11 +Glycosphingolipid metabolism 12 17 3.5430376436759747 0.0003955462364386 7.514563106796117 15.521844660194176 0.6340330218232789 0.1371235236408302 2.3948329397108954 1.2175929202976112 2.2116324239586063 0.2290247571497847 2.7278873335113235e-09 0.0108643857486399 1.4194050004739812e-05 3.292573095472588e-09 1.6712170470498703e-09 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 14 23 3.431459714842592 0.0006003422891591 6.014563106796117 17.274271844660195 0.870961683103299 0.329566970411291 2.8591161566949044 2.4465188670593117 1.2657234914365352 0.3108311955329007 2.526351715661311e-07 0.0295498589150116 1.4885597454595322e-05 0.0003789274231414 4.0901831486735546e-08 +Slc mediated transmembrane transport 17 26 3.348977649640557 0.0008111033845985 8.672330097087379 21.910194174757283 1.4735742044813558 0.239038892478899 4.348519601656105 3.146764860695784 1.3934177975338422 0.3068823132077037 1.0038780594540254e-07 0.3867386931517215 0.0731929968318565 0.0007457783870921 1.446687272672473e-06 +Glycosaminoglycan metabolism 9 14 3.230258711052642 0.0012367824898804 6.563106796116505 14.388349514563108 0.750167459040055 0.1742505874253542 2.387954817808654 2.3973407990867264 1.8682770414846892 0.2409021330213527 0.0004795230822878 0.2870659866655126 0.0045315560193572 6.419800009101929e-06 0.0019108778393583 +Transport of small molecules 57 150 3.1871449064614983 0.0014368476869268 41.730582524271846 151.96601941747574 1.4265613612661356 0.380396759556163 14.87709311863932 12.598305121005488 1.746958952072276 0.4128488770716938 4.3075851783952457e-17 0.1064647583825767 0.1545448473936569 4.168446221106459e-07 5.305958966387291e-16 +Trans golgi network vesicle budding 12 37 2.8667009318927232 0.0041477476669917 10.53640776699029 36.62378640776699 0.049458611821428 0.5755399655007756 4.812618396852807 3.083264760841391 1.1838693038940356 0.3533924794481698 9.22287925594324e-05 0.0043748091677711 0.0005115527825537 0.0002471633761616 2.258666281935264e-05 +Rab geranylgeranylation 14 18 2.849092241587196 0.0043844166861044 7.703883495145631 20.33009708737864 0.0425571144344789 0.6104117024455028 4.535157640190479 2.923418498732157 0.9174138709438756 0.3132937075649342 0.1743595432330578 1.0 1.0 0.7349303615645701 0.0457670040656382 +Cargo recognition for clathrin mediated endocytosis 13 34 2.818370214481606 0.0048268120284227 8.473300970873787 32.9126213592233 0.0802035091430913 0.5538966462673686 4.054455271697202 4.1286514785567014 1.088296749159732 0.3439390512580828 2.455399956807989e-06 0.0539251864958397 0.1724639155075248 0.000574878823084 1.9600289467223417e-05 +Cell surface interactions at the vascular wall 9 16 2.80285422430059 0.0050652558484634 4.95873786407767 15.691747572815531 0.5051863749151446 0.4839549723278067 2.507415479651395 2.585363930808798 0.9576767064205626 0.3154426595544552 0.0070970061158242 1.0 1.0 0.0068401475593005 0.006476918487605 +Intra golgi and retrograde golgi to er traffic 33 89 2.712439219735556 0.0066790028776517 23.762135922330096 91.83252427184466 0.7836914286379623 0.5449079285432085 8.961715947260837 10.213669235838784 1.1120768516172963 0.4008074869702365 4.287536326407647e-05 0.0109309682074606 0.0965212586027388 0.0045446840158695 6.363963400527423e-05 +Plasma lipoprotein assembly remodeling and clearance 11 20 2.646084940744717 0.0081429366582064 3.495145631067961 16.83495145631068 -0.156267225907303 0.3789468896930614 2.0090754595317124 2.280551318877052 1.3521243953392292 0.296420660396241 2.4040101743721253e-05 0.1755724648168266 0.3209553841799009 0.0155108289838298 9.884573920484636e-05 +Transport of inorganic cations anions and amino acids oligopeptides 8 12 2.64203581057292 0.0082409342073555 3.45873786407767 9.99514563106796 1.347451847228265 0.1988162564497566 2.1544143797408783 1.7967002462592632 1.0339867286779445 0.2465647399589519 5.397781717796104e-05 1.0 0.3467918934582977 0.0901467992310857 0.0002155385692345 +Death receptor signalling 4 26 2.554635928488877 0.0106298916418068 5.645631067961165 23.54126213592233 -0.1102863609457894 0.6465088441574995 3.539054689729852 5.442171393384637 0.8141573628490125 0.3087559956450991 0.5388434953655143 0.1131277718078383 0.1086360389997802 0.1660809858489837 0.6989088546616515 +Heparan sulfate heparin hs gag metabolism 4 6 2.524953772025041 0.011571350951542 2.4320388349514563 4.83252427184466 0.8003221575390526 0.2230961855611341 1.2648123228701085 1.2708877857521428 1.4628061886044337 0.2633127679646707 0.0086829766575463 0.1430638950507344 0.0376249374527164 0.0009447024772989 0.0179733508374719 +Golgi associated vesicle biogenesis 8 29 2.499463077618905 0.0124381659628698 8.759708737864077 29.70145631067961 0.0117084357140251 0.6100432040453254 4.8544872558395 2.3659596085838968 0.9746782938929878 0.3312452125247998 0.006435787265323 0.0285808600856777 0.0157478410048603 0.0104048104957299 0.0012031940780095 +Keratan sulfate keratin metabolism 4 5 2.3820332336802346 0.0172173435471385 3.1359223300970873 5.439320388349515 0.1148000450757159 0.1857420338858874 1.294488268568909 0.7592200419566036 1.8452752770630356 0.2520366769461069 0.0004396452857286 1.0 0.0113213926532688 3.906142953800441e-05 0.0010053263520343 +Stimuli sensing channels 4 9 2.3795046324231395 0.0173359251198075 3.075242718446602 8.648058252427184 0.6737384899082146 0.3285895756392196 1.7754169999219978 1.9694070657894505 1.2463928142905627 0.307032431313504 0.017765427736657 0.1675604235637086 0.3076603852203092 0.063688713570506 0.0353817250131281 +Ion channel transport 14 26 2.3784457211338177 0.0173857963353225 9.031553398058252 27.74271844660194 0.8980727715308076 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0.2414588001366878 0.0041482574964162 6.765318543664244e-05 0.0005309775927247 0.00062382482254 0.0010053263520343 +Plasma lipoprotein clearance 6 16 2.3230546674345542 0.0201762158492737 2.8980582524271843 13.347087378640778 -0.2018368930286127 0.3332067151933208 1.7692892864455283 1.6527165816198162 1.437154699054494 0.2826032943885157 2.372098591585584e-05 0.1049896535105009 0.1993869387044997 0.0020705519968491 7.568702219565374e-05 +Regulation of tnfr1 signaling 1 7 2.322539540135353 0.0202039019236397 1.8519417475728157 5.308252427184466 -0.1481549369001089 0.5006984721896415 1.5547987465385102 2.243573314566278 1.0080178191740088 0.2991677663727714 0.3593880565727997 0.1389130578490434 0.2590666885683055 0.1724444479617574 0.4482773855235765 +Sphingolipid de novo biosynthesis 5 10 2.282222523224599 0.0224762059938359 4.08252427184466 10.614077669902912 1.3205451179619188 0.2079933246203462 1.939118365602947 1.3614298144224892 1.289169434780902 0.261809046515659 0.0056546641425135 1.0 0.2445730022705269 0.1552222190730896 0.0023211498250519 +Rac2 gtpase cycle 14 33 2.266519261790439 0.0234196091782377 8.905339805825243 34.74757281553398 0.8419178475366841 0.4471774138928159 4.131135699306596 3.707034631516275 0.9898490308362274 0.3561406142763811 0.0003965025521504 0.0576595399457578 0.1827953867238 0.0136037852653257 0.0004978062317691 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 5 7 2.1635416786070425 0.0304995417008429 2.4441747572815533 5.640776699029126 0.4367607020315134 0.3723162326956727 1.3914754509602176 1.0870318448371576 1.21665608087566 0.3078849576437732 0.0195634506709255 1.0 1.0 0.0242110622206542 0.0074494564855197 +Mitochondrial protein import 8 34 2.158760492573839 0.0308687529809377 13.468446601941748 34.5873786407767 1.6025718162972953 0.1874419874946837 6.078090089851624 2.2108812815475147 1.8878681708577505 0.2901223460226844 0.0005590165980303 8.566885380985011e-06 0.0002457945313068 1.0845222485789932e-05 0.0001061774836938 +Gpcr ligand binding 4 9 2.1559951626468226 0.0310840428817211 3.4611650485436893 9.330097087378642 1.051447004644797 0.2131328881138611 1.5951828582954857 1.3192992367203638 1.3003237502897853 0.2397874119507845 0.0373709737660068 0.0204708743585679 0.0720571885403784 0.0247625444605767 0.0707827064406983 +Clathrin mediated endocytosis 15 56 2.155437887730876 0.0311275842077021 13.347087378640778 54.61165048543689 -0.1902727778750813 0.6211571238833282 6.558431633951774 5.961418039601661 0.9253143323693156 0.3262498062687709 2.2910637981964108e-05 0.1115719060554689 0.317502679856318 0.0023720934204197 0.000195788501881 +Antigen presentation folding assembly and peptide loading of class i mhc 6 15 2.135050989474599 0.0327568453520257 4.368932038834951 15.359223300970871 0.4885439583196688 0.552320665891318 2.1553288725341515 1.853123151913033 0.7873077885530996 0.3087027768162914 0.0003077778908145 1.0 1.0 0.0195244436529747 0.0001024209024739 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pathways 3 11 2.07570086410296 0.0379216259840724 2.342233009708738 10.851941747572816 0.4093935303592591 0.5118730029355861 2.0859825428338192 2.5513980779067897 0.8583599781783465 0.2979240057989124 0.0889016456319048 0.1835089509173778 0.3339976348230559 0.2707185745648809 0.1451121707049519 +Rhoa gtpase cycle 14 46 2.0745038573021537 0.0380325408937787 11.383495145631068 46.157766990291265 0.7285935948010234 0.4866370775942555 5.135874153241841 5.803151375541917 0.959659542192298 0.3649179877597411 0.0030215583338199 0.1354750356227081 0.3700525131557232 0.0161335998015439 0.0021062495932256 +Metabolism of fat soluble vitamins 6 7 2.0740425870762857 0.0380753558729074 1.6650485436893203 4.580097087378641 0.3536798037155611 0.3331745511018804 1.178052427490116 1.3130753903966457 1.3422038796699125 0.2910915635007025 0.0282735799915187 1.0 1.0 0.0049571663496986 0.0119362160344991 +Ire1alpha activates chaperones 7 23 2.0702909471576394 0.0384251068330212 6.050970873786408 24.223300970873787 0.9379365742980283 0.4047880585679882 2.6930013625985207 2.1985522104416564 1.0262193137091864 0.3353529084578252 0.00815731977733 0.0188245552589776 0.0666692325567911 0.0901467992310857 0.00110124435718 +Rhog gtpase cycle 14 34 2.0690186613910337 0.038544335562217 9.8373786407767 35.66504854368932 0.6614029400837433 0.4973720188279035 4.308521802053122 2.993429981792782 0.9950331841901028 0.3588671909523165 2.432398493335676e-05 0.290515894493261 0.497470817800254 0.0015979936813088 3.1066114222159566e-05 +Lysosome vesicle biogenesis 4 15 2.061157677833976 0.0392879996893673 4.155339805825243 14.065533980582524 0.0338045297007374 0.5442845091130821 2.9436694673613903 1.5836165002042342 1.0229669221105775 0.3256487992521382 0.0086829766575463 0.1430638950507344 0.0376249374527164 0.0415700360883472 0.0179733508374719 +Diseases of glycosylation 8 18 2.031272662355672 0.0422273429493671 6.359223300970874 19.17718446601942 0.13180823173309 0.3045208720095976 2.4657040544471793 2.991113672999948 1.5111068586159069 0.284004628008759 0.0115004056660911 1.0 0.1656331484196294 0.0023719924306961 0.0109943535003159 +Peptide hormone metabolism 4 13 2.0293034004445576 0.042427397182154 4.021844660194175 14.021844660194176 0.5560275504881529 0.5205961274891826 2.4979619838894513 2.4069092486442756 0.8833525414026219 0.3339695456705046 0.0950522892119901 0.187449079081247 0.0640285846884502 0.2797556636969028 0.0558327828623465 +P75 ntr receptor mediated signalling 2 17 2.0270470814230683 0.0426575979695316 3.701456310679612 15.682038834951456 -0.0299058777713717 0.6575383124807638 3.016250133767169 3.3360880116976555 0.736249447013267 0.2885137825083352 0.6431230145127514 0.3241278561278478 0.1827953867238 0.3128952059925546 0.7602385831063151 +Ovarian tumor domain proteases 0 10 2.017770566901416 0.0436151615927278 3.3009708737864076 8.611650485436893 -0.0545895007385164 0.62605422182602 2.3558848087632325 1.442981068232173 0.7775147818170627 0.2913094692521883 0.7554179000805259 0.151306852499084 0.2802926639431586 0.5661975770404395 0.8163778738551817 +Intra golgi traffic 7 13 2.003696302526662 0.0451026025991612 4.424757281553398 13.87135922330097 0.7636302424906817 0.4243971711811651 2.688824171738392 3.845367291797066 0.9598354803720488 0.3140361333882177 0.0889016456319048 1.0 1.0 0.0808776862517318 0.051296284939533 +Signaling by erbb4 2 7 2.0023158840678628 0.0452507687292471 2.453883495145631 7.257281553398058 0.4395977843708076 0.5106764734442939 1.5549199917041956 1.4851433811168728 0.8250198774172108 0.2950845076560141 0.1776374851388814 1.0 1.0 0.5870305126491255 0.2535314416198171 +Transport of vitamins nucleosides and related molecules 6 8 1.9881454117558848 0.0467956102099333 3.2985436893203883 7.703883495145631 0.5884630304197642 0.3368828823659784 1.766928610360549 0.9135891377639136 1.2550983698791685 0.3076045725047946 0.00917939970768 1.0 0.1837383274168749 0.0135296171343662 0.017002584405276 +Integrin cell surface interactions 4 5 1.964149361777372 0.049512773234563 1.633495145631068 4.203883495145631 0.3179111363730327 0.4479127776597527 1.2499104501809644 0.9864049002328192 1.1220147725505705 0.3186356661300093 0.0612241796762722 1.0 1.0 0.0596874537258691 0.1028731839020021 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9dbb14457a4896768a376fc300469d1bfe8a669a --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 1393, + "title": "Average number of proteins per term", + "value": 18.91313711414214 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..56ccde8ae026fff056bd0eea2dd83d4c14a35a5f --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..253fb52a384bea567cc5f513cc89b57ea104f3ab --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,388 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Sphingolipid metabolism 0.7985316912232199 3.5774645834441707 0.00034694321028 0.3833019436823583 0.2754979536795349 27 P04062,P16278,P06865,Q96G23,P10619,P06280,Q8TCT0,O95470,P07686,Q99519,P07602,O15269,Q16739,P17900,P51648,P27544,Q13510,Q9NZJ7 18 +Glycosphingolipid metabolism 0.8543705453583452 3.5430376436759747 0.0003955462364386 0.423687314196379 0.2754979536795349 17 P04062,P16278,P06865,P06280,P10619,P07686,Q8TCT0,Q99519,P07602,Q16739,P17900,Q13510 12 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.7805585276663239 3.431459714842592 0.0006003422891591 0.5667879445794802 0.2787589362662429 23 Q8NBJ4,O43493,P19022,Q02818,Q06481,P04114,O76024,Q9BTY2,Q08431,Q07065,P07942,P07237,P05067,O43852 14 +Slc mediated transmembrane transport 0.7627748302774398 3.348977649640557 0.0008111033845985 0.6770718680282526 0.2824667536864471 26 Q8NEW0,Q96QD8,Q8TB61,P55011,P35613,P12235,P08195,P12236,Q70HW3,P05141,Q9UBX3,Q9Y6M7,P14672,P30825,P04920,P11166,Q92581 17 +Glycosaminoglycan metabolism 0.8601170024293641 3.230258711052642 0.0012367824898804 0.8216316126686056 0.3335881379815213 14 P54802,Q8TB61,P16278,P06865,P07686,Q7LGA3,O43505,P15586,Q9Y251 9 +Transport of small molecules 0.5553251303823121 3.1871449064614983 0.0014368476869268 0.8650658170073868 0.3335881379815213 150 P61289,Q9UNS2,Q96QD8,P61916,P55011,P09601,P45880,Q70HW3,Q8N4V1,P05023,P51798,P05141,Q9Y6M7,P04114,Q9C0H2,P04920,P21796,Q15043,Q9BUN8,P07237,Q96PU5,Q8NEW0,P30519,O15118,P02786,P40855,P49721,P98155,Q93050,P60900,P14672,Q8IYU8,Q9HD20,Q9Y6B6,Q9BPX6,P01130,P10644,Q8TB61,P08195,P38571,P16615,Q04656,P30825,Q15904,Q92581,P35613,P12235,Q8WTV0,P12236,Q9Y487,Q9UBX3,P51790,P11166,Q4KMQ2,Q9Y277,O95202,P36543 57 +Trans golgi network vesicle budding 0.6691367111055603 2.8667009318927232 0.0041477476669917 0.9969414923900636 0.4703934264606346 37 P51809,Q92572,O43493,O75976,P02786,Q99523,P11717,P15586,P20645,P51148,P05067,O00115 12 +Rab geranylgeranylation 0.7099870811458552 2.849092241587196 0.0043844166861044 0.9978035670124916 0.4703934264606346 18 P20339,Q9BZG1,P61020,Q15286,P53611,Q9H0U4,Q14964,Q969Q5,P62820,P61019,P51149,P51148,Q9NP72,P51151 14 +Cargo recognition for clathrin mediated endocytosis 0.6680840768851692 2.818370214481606 0.0048268120284227 0.9988173867835688 0.4703934264606346 34 O14657,P51809,O43493,P98164,P02786,Q99627,P00533,P11717,P04114,Q14108,Q9BT78,P20645,P01130 13 +Cell surface interactions at the vascular wall 0.7416206065629521 2.80285422430059 0.0050652558484634 0.9991530187021224 0.4703934264606346 16 P54709,Q9UNN8,Q9Y624,P35613,P06756,P08195,Q92896,Q08722,P04114 9 +Intra golgi and retrograde golgi to er traffic 0.4639913958171924 2.712439219735556 0.0066790028776517 0.9999117255877672 0.5472853534452307 89 O43731,O43493,O60499,Q9P2W9,P62820,P54920,Q9NP72,P51151,P24390,Q9H0U4,Q10472,P20645,Q9UID3,P33908,Q8TBA6,Q9H0H5,P04350,Q15042,Q7Z6M1,Q9Y3B3,Q16706,Q10471,Q14964,P49755,O95249,Q13190,O15260,Q6NUQ1,P11717,Q15363,Q13561,O00461,O75935 33 +Plasma lipoprotein assembly remodeling and clearance 0.656724681975513 2.646084940744717 0.0081429366582064 0.9999886868651716 0.5600322688361531 20 O15118,P61916,P17612,Q8WTV0,P98155,P38571,P35610,P04114,Q9Y6B6,P07237,P01130 11 +Transport of inorganic cations anions and amino acids oligopeptides 0.778603712798119 2.64203581057292 0.0082409342073555 0.9999901415760178 0.5600322688361531 12 Q96QD8,P55011,P08195,Q70HW3,Q9UBX3,P30825,P04920,Q92581 8 +Death receptor signalling 0.639736399518879 2.554635928488877 0.0106298916418068 0.9999996573999134 0.5600322688361531 26 Q13501,Q8TCT8,Q86VP1,Q9NQC3 4 +Heparan sulfate heparin hs gag metabolism 0.8997239380630869 2.5249537720250412 0.011571350951542 0.9999999090427548 0.5600322688361531 6 P54802,Q7LGA3,P16278,Q9Y251 4 +Golgi associated vesicle biogenesis 0.6289904955206881 2.499463077618905 0.0124381659628698 0.9999999732042144 0.5600322688361531 29 P51809,Q92572,O43493,O75976,P02786,Q99523,P11717,P51148 8 +Keratan sulfate keratin metabolism 0.9291338582677175 2.3820332336802346 0.0172173435471385 0.9999999999688632 0.5600322688361531 5 P16278,P06865,P15586,P07686 4 +Stimuli sensing channels 0.7823809080928247 2.3795046324231395 0.0173359251198075 0.9999999999736806 0.5600322688361531 9 Q9C0H2,Q4KMQ2,P51798,P51790 4 +Ion channel transport 0.6139583970839317 2.3784457211338177 0.0173857963353225 0.9999999999754772 0.5600322688361531 26 P20020,Q9Y487,Q93050,P05023,P16615,Q04656,P51798,P51790,Q15904,Q9C0H2,Q4KMQ2,Q9HD20,Q96PU5,P36543 14 +Tnf signaling 0.7750890090549937 2.344166505038374 0.0190696560421688 0.9999999999977512 0.5600322688361531 9 Q86VP1 1 +Mitophagy 0.7338458558109968 2.342370093218379 0.0191617033454838 0.9999999999980268 0.5600322688361531 11 Q9NS69,Q13501,Q8N4H5 3 +Pink1 prkn mediated mitophagy 0.8013476739328663 2.3304843003025786 0.0197805688459686 0.9999999999991808 0.5600322688361531 8 Q9NS69,Q13501,Q8N4H5 3 +Plasma lipoprotein clearance 0.659438575574383 2.3230546674345542 0.0201762158492737 0.9999999999995332 0.5600322688361531 16 O15118,P61916,P98155,P38571,P04114,P01130 6 +Regulation of tnfr1 signaling 0.8288373194448538 2.322539540135353 0.0202039019236397 0.9999999999995512 0.5600322688361531 7 Q86VP1 1 +Sphingolipid de novo biosynthesis 0.7338489434599519 2.282222523224599 0.0224762059938359 0.9999999999999823 0.5600322688361531 10 Q96G23,O95470,O15269,P51648,P27544 5 +Rac2 gtpase cycle 0.5918616794594586 2.266519261790439 0.0234196091782377 0.9999999999999954 0.5600322688361531 33 Q9H0H5,P42167,Q6IAA8,Q14739,P02786,P05556,P43121,Q14126,Q86XL3,Q8TAA9,O15173,Q13505,P51149,P50402 14 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.7940737013891415 2.1635416786070425 0.0304995417008429 1.0 0.5600322688361531 7 P01889,P10321,P04439,Q5KU26,Q92692 5 +Mitochondrial protein import 0.5760672413196853 2.158760492573839 0.0308687529809377 1.0 0.5600322688361531 34 Q9NS69,P12235,Q8N4H5,P12236,O60830,Q13505,P21796,Q99595 8 +Gpcr ligand binding 0.7367842725539563 2.1559951626468226 0.0310840428817211 1.0 0.5600322688361531 9 P07602,P05067,P42892,P48960 4 +Clathrin mediated endocytosis 0.5284309367473291 2.155437887730876 0.0311275842077021 1.0 0.5600322688361531 56 O14657,P51809,Q9UNS2,O43493,P98164,P02786,P61020,Q99627,P00533,P11717,P04114,Q14108,Q9BT78,P20645,P01130 15 +Keratan sulfate degradation 0.9330928173171495 2.14701763512888 0.031791877681675 1.0 0.5600322688361531 4 P15586,P06865,P16278 3 +Antigen presentation folding assembly and peptide loading of class i mhc 0.6431788001365121 2.135050989474599 0.0327568453520257 1.0 0.5600322688361531 15 P01889,P10321,P04439,Q03518,Q9NZ08,Q9Y6B6 6 +Synaptic adhesion like molecules 0.7874724147537816 2.1330126248595915 0.0329236905612431 1.0 0.5600322688361531 7 O95197,O75955,P10586 3 +Binding and uptake of ligands by scavenger receptors 0.7304616113571022 2.1245225336070743 0.0336264738504255 1.0 0.5600322688361531 9 Q07954,P04114,Q5KU26 3 +Mitochondrial calcium ion transport 0.6410524215829597 2.1223919530960296 0.0338048373750501 1.0 0.5600322688361531 15 P45880,Q8IYU8,P21796,Q9Y277,O95202 5 +Mucopolysaccharidoses 0.9219416202033408 2.1026811121687876 0.0354936542108996 1.0 0.5600322688361531 4 P16278,P54802,P15586 3 +Hs gag degradation 0.9219416202033408 2.102681112168785 0.0354936542108998 1.0 0.5600322688361531 4 P16278,P54802,Q9Y251 3 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.6831419285574363 2.07570086410296 0.0379216259840724 1.0 0.5600322688361531 11 Q96J02,P05067,P09601 3 +Scavenging by class a receptors 0.9150674634900792 2.075251150299164 0.0379632642557201 1.0 0.5600322688361531 4 Q5KU26 1 +Rhoa gtpase cycle 0.5452821732563689 2.0745038573021537 0.0380325408937787 1.0 0.5600322688361531 46 Q9H0H5,P30519,P42167,Q13190,P02786,Q14739,Q07021,O75955,P43121,Q8NBN3,Q15904,Q8TAA9,O15173,Q96HY6 14 +Metabolism of fat soluble vitamins 0.7747866053840955 2.0740425870762857 0.0380753558729074 1.0 0.5600322688361531 7 Q6NUM9,P98164,Q8TC12,Q07954,P04114,P01130 6 +Ire1alpha activates chaperones 0.5708090845871606 2.0702909471576394 0.0384251068330212 1.0 0.5600322688361531 23 O43731,Q9Y5M8,P43307,O95070,O76024,O14773,Q9HCU5 7 +Rhog gtpase cycle 0.5640604847640781 2.0690186613910337 0.038544335562217 1.0 0.5600322688361531 34 Q13190,P42167,Q6IAA8,Q14739,P02786,Q96JJ3,O95202,P43121,Q14126,Q86XL3,Q8TAA9,O15173,P51149,P50402 14 +Lysosome vesicle biogenesis 0.630810237741013 2.0611576778339757 0.0392879996893673 1.0 0.5600322688361531 15 P15586,P20645,P05067,O00115 4 +Vitamin d calciferol metabolism 0.9061987536897322 2.039752077800832 0.0413750250718856 1.0 0.5600322688361531 4 Q99538,P98164,P38435 3 +Diseases of glycosylation 0.5812026979461198 2.031272662355672 0.0422273429493671 1.0 0.5600322688361531 18 Q9BV10,P16278,P06865,Q9BT22,P10619,P07686,Q99519,O43505 8 +Peptide hormone metabolism 0.6515041814254363 2.0293034004445576 0.042427397182154 1.0 0.5600322688361531 13 Q8NEW0,Q15005,O75787,P16870 4 +P75 ntr receptor mediated signalling 0.5961695386678405 2.0270470814230683 0.0426575979695316 1.0 0.5600322688361531 17 Q13501,Q9NQC3 2 +Intra golgi traffic 0.6469966325024751 2.003696302526662 0.0451026025991612 1.0 0.5600322688361531 13 O95249,Q8TBA6,Q13190,Q16706,Q14964,O00461,P33908 7 +Signaling by erbb4 0.7594700394783866 2.0023158840678628 0.0452507687292471 1.0 0.5600322688361531 7 Q96J02,Q92542 2 +Endosomal vacuolar pathway 0.89439160380452 1.9923005301448071 0.046338093576919 1.0 0.5600322688361531 4 P04439,Q9UIQ6,P10321 3 +Transport of vitamins nucleosides and related molecules 0.7298191866214465 1.9881454117558852 0.0467956102099333 1.0 0.5600322688361531 8 Q99808,P12235,Q8TB61,P12236,P05141,O00400 6 +Integrin cell surface interactions 0.8297244094488081 1.964149361777372 0.049512773234563 1.0 0.5600322688361531 5 Q9Y624,P35613,Q08722,P06756 4 +Ldl clearance 0.6374523655087663 1.9492296782242844 0.0512680022266474 1.0 0.5600322688361531 13 O15118,P61916,P38571,P35610,P04114,P01130 6 +Iron uptake and transport 0.5795192589043012 1.9193132452154469 0.0549447027578706 1.0 0.5600322688361531 17 P30519,P02786,P09601,Q9Y487,Q93050,Q15904 6 +Tbc rabgaps 0.6320524139271476 1.9182658094723584 0.0550773154050494 1.0 0.5600322688361531 13 P20339,P61020,Q8TC07,P51149,P49815,P51148 6 +Ecm proteoglycans 0.8187993215909071 1.9170811133771757 0.0552276276273056 1.0 0.5600322688361531 5 P07942,P06756,P05067 3 +Laminin interactions 0.8176113754862795 1.9119499271015343 0.0558826169190418 1.0 0.5600322688361531 5 P14543,P07942,P06756 3 +Transferrin endocytosis and recycling 0.6596714354606796 1.896453079018506 0.0579001588306473 1.0 0.5618794316825064 10 Q93050,Q15904,P02786,Q9Y487 4 +Dap12 interactions 0.8706808931736802 1.8963662591299784 0.057911630260202 1.0 0.5618794316825064 4 P10321 1 +Diseases of carbohydrate metabolism 0.7076616950925929 1.8793213814454797 0.0602006239146222 1.0 0.5645998259723031 8 P54802,P16278,P10253,P15586 4 +Class a 1 rhodopsin like receptors 0.730733960552054 1.866204504871962 0.0620127590622845 1.0 0.5645998259723031 7 P07602,P05067,P42892 3 +Peptide ligand binding receptors 0.730733960552054 1.866204504871962 0.0620127590622845 1.0 0.5645998259723031 7 P07602,P05067,P42892 3 +Visual phototransduction 0.6771236026437589 1.8543626668228737 0.0636872921497375 1.0 0.5660432702641692 9 Q07954,P04114,P01130,P49356 4 +Class i peroxisomal membrane protein import 0.7017782563137709 1.8502082354404932 0.0642835424500214 1.0 0.5667530040055687 8 Q5T8D3,O43808,P40855,O75381,P51648,Q8TB36 6 +Transport to the golgi and subsequent modification 0.4263168044782229 1.8465247295726752 0.0648160520607703 1.0 0.5678538397525351 75 O43731,P62820,O00743,P24390,P04066,Q9H0U4,P53634,Q14789,Q9Y6B6,P33908,P04350,Q9Y3B3,Q16706,P26572,Q9HCU5,P49755,Q13190,O95249,Q12907,Q15363,Q13561,O75935 22 +Amyloid fiber formation 0.6750333674166854 1.843607436492341 0.0652403714773377 1.0 0.5679989841745717 9 P05067,Q9Y287,Q92542,Q92673 4 +Inflammasomes 0.8475143832831594 1.8018344531766208 0.0715714553567434 1.0 0.581664795586131 4 P05067 1 +Purinergic signaling in leishmaniasis infection 0.8475143832831594 1.8018344531766208 0.0715714553567434 1.0 0.581664795586131 4 P05067 1 +The nlrp3 inflammasome 0.8475143832831594 1.8018344531766208 0.0715714553567434 1.0 0.581664795586131 4 P05067 1 +Insulin processing 0.6913849321224974 1.7985589982678036 0.072088468122007 1.0 0.581664795586131 8 Q8NEW0 1 +Hyaluronan uptake and degradation 0.7821266631878687 1.7575180506624468 0.0788295478710705 1.0 0.581664795586131 5 P06865,P07686 2 +Hyaluronan metabolism 0.7821266631878687 1.7575180506624468 0.0788295478710705 1.0 0.581664795586131 5 P06865,P07686 2 +Protein protein interactions at synapses 0.5924620271220249 1.754058810752915 0.0794204304665844 1.0 0.581664795586131 14 O95197,O75955,P10586 3 +Rnd1 gtpase cycle 0.6008136060825368 1.7370690191807778 0.0823749890014768 1.0 0.581664795586131 13 Q9BXS4,O75976,P02786,P51648 4 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.6196485503367489 1.7296799811704906 0.0836874672996612 1.0 0.581664795586131 11 P51648,P05067,P09601 3 +Ddx58 ifih1 mediated induction of interferon alpha beta 0.5594546675073563 1.7006295069375974 0.0890125797673822 1.0 0.581664795586131 16 Q86VP1,P05067 2 +Trafficking and processing of endosomal tlr 0.9278490585189982 1.6963054037467258 0.0898280576581855 1.0 0.581664795586131 3 P07858 1 +Basigin interactions 0.7674996552991553 1.6932322818117858 0.09041126216573 1.0 0.581664795586131 5 P54709,P08195,P35613 3 +Plasma lipoprotein assembly 0.8209248934076635 1.6924232105067607 0.0905653099531256 1.0 0.581664795586131 4 Q9Y6B6,P04114,P07237 3 +Response to elevated platelet cytosolic ca2 0.5175993287998615 1.6921829372237591 0.0906110988098998 1.0 0.581664795586131 29 Q08380,O94919,Q9NZJ7,Q8NBX0,Q9NUQ9,Q06481,P07602,Q96JJ7,P05067,O43852 10 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.7657480314960408 1.6855105153987882 0.0918901177576783 1.0 0.583261600246269 5 Q99808,P05141,P12235,P12236 4 +Rac3 gtpase cycle 0.5153286434617459 1.6854400298025811 0.0919037059822895 1.0 0.583261600246269 32 Q9H0H5,P42167,Q6IAA8,Q9UQB8,P02786,Q14739,P05556,P43121,Q14126,Q8TAA9,O15173,P51149,P50402 13 +Rab gefs exchange gtp for gdp on rabs 0.5167370437465205 1.680917451377672 0.0927789497431201 1.0 0.583261600246269 25 P20339,P61020,Q15042,Q14964,P51149,P62820,P51148,P31751,P51151 9 +Transport of bile salts and organic acids metal ions and amine compounds 0.8161358328944346 1.6726200724020457 0.0944021128528538 1.0 0.583261600246269 4 Q8NEW0,P35613 2 +Glycerophospholipid biosynthesis 0.5141320981637392 1.6617350011463248 0.0965659199250157 1.0 0.583261600246269 26 Q96N66,Q8NCC3,Q9UG56,Q8IV08,Q9NPH0,O14735,P48651,Q9NQZ5,P35790,Q53H12 10 +Translation of sars cov 1 structural proteins 0.6857458158607872 1.6492072081902456 0.0991051917402561 1.0 0.583261600246269 7 P26572,P27824,Q10472 3 +Pexophagy 0.9158673222428688 1.648894574971721 0.099169234751637 1.0 0.583261600246269 3 Q13501 1 +Non integrin membrane ecm interactions 0.7044250711600267 1.6426304185667286 0.1004594231721682 1.0 0.583261600246269 6 P07942,P06756 2 +O linked glycosylation 0.8081338143653544 1.6394689348657658 0.1011156352681408 1.0 0.583261600246269 4 Q10472,O43505,Q10471 3 +O linked glycosylation of mucins 0.8081338143653544 1.6394689348657658 0.1011156352681408 1.0 0.583261600246269 4 Q10472,O43505,Q10471 3 +Diseases associated with n glycosylation of proteins 0.7037154925987579 1.639272408921872 0.1011565395603988 1.0 0.583261600246269 6 Q9BT22,Q9BV10 2 +Degradation of the extracellular matrix 0.5821349799197791 1.6270820527538217 0.1037196722011466 1.0 0.584565695002343 13 P07858,P14543,P35613,Q92542 4 +Retrograde transport at the trans golgi network 0.5583087488362987 1.6155851101240288 0.1061840453340714 1.0 0.5885170448831135 15 O43493,O60499,Q7Z6M1,P11717,P54920,P20645,Q9UID3,P51151 8 +Amino acid transport across the plasma membrane 0.7999344047228452 1.6054224069321728 0.1084008765510979 1.0 0.589853207170623 4 P08195,Q96QD8,P30825 3 +Cristae formation 0.5033762079515715 1.5965332150290596 0.1103697961473537 1.0 0.5959113412142008 19 Q16891,Q9NVH1,O75964,Q9BUR5,Q9Y512,Q6UXV4,Q13505,Q5XKP0 8 +Cargo concentration in the er 0.5649590126185462 1.5871904691241718 0.11246951271429 1.0 0.5979772183626185 14 P49755,Q13190,P53634,Q12907,Q15363,Q9HCU5,Q9Y6B6 7 +Selective autophagy 0.5024426482942947 1.582095512777265 0.1136277678463575 1.0 0.5993404775214262 31 Q9NS69,Q14596,Q13501,Q8N4H5 4 +Vldl clearance 0.9528023598820106 1.556520326201328 0.1195844130903429 1.0 0.6147784182941445 2 P98155 1 +Interferon gamma signaling 0.5586290088105412 1.5484069146220691 0.1215243574880722 1.0 0.6147784182941445 14 P04439,P10321,P15260 3 +Rab regulation of trafficking 0.4969750100696309 1.5471124796816786 0.1218361251522046 1.0 0.6147784182941445 33 P20339,P61020,Q15042,Q8TC07,Q9H0U4,Q14964,P51149,P62820,P49815,P51148,P31751,P51151 12 +Sialic acid metabolism 0.7328536002108438 1.5396323586148395 0.1236499932478674 1.0 0.6151587164081403 5 P16278,P10619 2 +Phospholipid metabolism 0.489006776978688 1.5134931693695717 0.1301544349087791 1.0 0.6285549187543373 38 Q8NF37,P20339,Q96N66,Q8NCC3,Q9UG56,Q9UBF8,Q8IV08,Q9NTJ5,Q9BTU6,Q9NPH0,O14735,P48651,Q9NQZ5,P35790,Q53H12 15 +Signaling by insulin receptor 0.5526862506014404 1.511873233227322 0.1305661145856171 1.0 0.6285549187543373 14 Q93050,Q15904,P31751,Q9Y487 4 +Chylomicron clearance 0.938708620124549 1.4981185116764326 0.1341024623229889 1.0 0.6285549187543373 2 P04114 1 +Chondroitin sulfate dermatan sulfate metabolism 0.8771319921285258 1.4949871382287532 0.1349177988653065 1.0 0.6285549187543373 3 P06865 1 +Diseases associated with glycosaminoglycan metabolism 0.8771319921285258 1.4949871382287532 0.1349177988653065 1.0 0.6285549187543373 3 P06865 1 +Signal amplification 0.7194881889763722 1.47992814399911 0.1388924239409894 1.0 0.6285549187543373 5 Q14344,P04899,Q13685,P08754 4 +Nrif signals cell death from the nucleus 0.9331366764995171 1.4750308581324645 0.1402042474203955 1.0 0.6285549187543373 2 Q13501 1 +Cs ds degradation 0.9324811537200977 1.4723148948609663 0.1409358629181012 1.0 0.6285549187543373 2 P06865 1 +Toll like receptor cascades 0.4878488669496259 1.4640449268348017 0.1431816733669639 1.0 0.6289124849027741 28 P04114,P07858,P05067 3 +Constitutive signaling by akt1 e17k in cancer 0.6468889518885207 1.458263245082858 0.1447679970620012 1.0 0.6289124849027741 7 P49815,P42345,P31751 3 +Cell death signalling via nrage nrif and nade 0.5709081947936959 1.4553589911848526 0.1455699031689541 1.0 0.6289124849027741 11 Q13501 1 +Chylomicron assembly 0.8659016393442609 1.4502338145640012 0.1469933284771565 1.0 0.6304357872442852 3 Q9Y6B6,P04114 2 +Pregnenolone biosynthesis 0.7618743690874628 1.4464794632373132 0.1480427681075877 1.0 0.6306531375347698 4 Q14849 1 +Metabolism of steroid hormones 0.6628518837406878 1.4443213180230767 0.1486486118783356 1.0 0.6312122250566702 6 Q14849 1 +Eph ephrin mediated repulsion of cells 0.5575202147750739 1.426303576721099 0.1537807326340206 1.0 0.6389895268114132 12 Q15375 1 +Copii mediated vesicle transport 0.4795220755583513 1.4017372028284083 0.1609937368646068 1.0 0.6512551503109455 30 P49755,Q13190,P53634,Q9H0U4,Q12907,Q15363,P62820,O00743,P54920,Q9Y6B6,Q9HCU5 11 +Insulin receptor recycling 0.5874933371987242 1.3826015442646584 0.1667870753063016 1.0 0.6620316620680722 9 Q93050,Q15904,Q9Y487 3 +Notch3 activation and transmission of signal to the nucleus 0.7465762058020724 1.382250512452081 0.1668947952390447 1.0 0.6620316620680722 4 Q92542 1 +Rhoc gtpase cycle 0.4755735928336413 1.3778790385198096 0.1682406377401992 1.0 0.6620316620680722 33 Q9H0H5,P42167,Q13190,Q14739,P02786,Q07021,O75955,P43121,Q8TAA9 9 +Activated notch1 transmits signal to the nucleus 0.9082268108816776 1.3719015857060757 0.1700940767061487 1.0 0.6630458772210152 2 Q92542 1 +Rhod gtpase cycle 0.4756289534559578 1.370285830595661 0.1705976944078213 1.0 0.6630458772210152 27 Q9H0H5,P42167,Q14739,P43121,Q9Y6M7,Q8TAA9,O15173,P50402 8 +Ion homeostasis 0.5818884848043626 1.3524553055823385 0.1762297073465171 1.0 0.6664107248520128 9 P54709,P16615,P20020,P05023 4 +Cardiac conduction 0.5818884848043626 1.3524553055823385 0.1762297073465171 1.0 0.6664107248520128 9 P54709,P16615,P20020,P05023 4 +Synthesis of pe 0.9023271058669284 1.3475132722507304 0.1778149817954997 1.0 0.6664107248520128 2 P35790 1 +Cellular hexose transport 0.9013438216978038 1.3434505066715507 0.1791261419587406 1.0 0.6689617044196401 2 P11166 1 +Rhoj gtpase cycle 0.4679881590699679 1.3379882811122934 0.1809002569649196 1.0 0.6719841545390214 19 P42167,Q6IAA8,P02786,Q9Y6M7,Q8TAA9,P51149 6 +Neutrophil degranulation 0.4239229279052921 1.334347208533866 0.1820900927033539 1.0 0.6730558009720208 181 P61916,O75629,Q08722,P10619,Q99519,P07602,P07858,P30519,P10321,P61020,O00584,Q93050,P04066,P53634,P06280,O00560,Q92820,O00754,Q07065,P15586,Q9NQX7,Q13510,P06756,O75787,P01889,P16278,Q92542,P07686,Q9H8H3,Q9BTY2,P17900,O00264,P10253,Q9Y251,O00462,O15260,P48960,P04439,Q9NV96,P11717,P08236,Q4KMQ2,Q8WVQ1,P11279 44 +Sars cov 1 infection 0.5332868746725579 1.3341488237846948 0.1821550875566775 1.0 0.6730558009720208 13 O43633,P27824,P14314,P26572,Q10472 5 +Energy dependent regulation of mtor by lkb1 ampk 0.6202384479777394 1.3257042449841578 0.184937680792022 1.0 0.6743931658201221 7 Q9HB90,Q6IAA8,P42345 3 +Protein localization 0.3981267578318891 1.307006559366949 0.1912104837748431 1.0 0.6793616878574689 70 Q9NS69,Q13190,P12235,Q8N4H5,P09601,P12236,P39210,O60830,O14925,Q13505,P51648,P21796,P05067,Q99595 14 +Ripk1 mediated regulated necrosis 0.5444729030284858 1.303825351260108 0.1922931368377693 1.0 0.6793616878574689 11 Q14254,O75955,O00560 3 +Mtor signalling 0.4982571356787957 1.299572419087025 0.1937475577820862 1.0 0.6793616878574689 16 Q6IAA8,P62942,Q9HB90,P42345,P49815,P31751 6 +Scavenging by class b receptors 0.8829891838741493 1.2677409461867244 0.2048904772125359 1.0 0.6850358449829325 2 P04114 1 +Negative regulation of nmda receptor mediated neuronal transmission 0.6261437029570145 1.2669679922472 0.2051667350013652 1.0 0.6850358449829325 6 P07196,Q13555,Q92796,Q14168 4 +Ras activation upon ca2 influx through nmda receptor 0.6719160104986835 1.2658691567103395 0.2055599305117486 1.0 0.6850358449829325 5 P07196,Q13555,Q92796,Q14168 4 +Unblocking of nmda receptors glutamate binding and activation 0.6719160104986835 1.2658691567103395 0.2055599305117486 1.0 0.6850358449829325 5 P07196,Q13555,Q92796,Q14168 4 +Long term potentiation 0.6719160104986835 1.2658691567103395 0.2055599305117486 1.0 0.6850358449829325 5 P07196,Q13555,Q92796,Q14168 4 +Formation of fibrin clot clotting cascade 0.8180327868852408 1.259313199967798 0.2079172272963241 1.0 0.6854460422185756 3 Q9UNN8,Q07021 2 +Heme degradation 0.7167407915612777 1.2566415485066291 0.208883462579112 1.0 0.6854460422185756 4 P09601 1 +Assembly and cell surface presentation of nmda receptors 0.5430524700913999 1.2560656222301874 0.209092178928423 1.0 0.6854460422185756 10 P04350,Q92796,Q13555,Q15334,Q14168,P07196,Q9BUF5 7 +Metabolism of porphyrins 0.5635157562030013 1.2532192560066349 0.210125923987396 1.0 0.6854460422185756 9 P09601,Q7KZN9 2 +Platelet homeostasis 0.5840460667205248 1.2504088480491065 0.2111502340506836 1.0 0.6854521076939956 8 P04114,P16615 2 +Pi3k akt signaling in cancer 0.5193151966389232 1.249150087718901 0.2116101836772395 1.0 0.6854521076939956 13 P42345,P00533,P49815,Q96B36,P31751 5 +Akt phosphorylates targets in the cytosol 0.6194102809979128 1.2342655286179036 0.2171039765279911 1.0 0.690469952747698 6 P49815,P31751 2 +Extracellular matrix organization 0.4569720835828529 1.2290533618548352 0.2190517996333643 1.0 0.6935225942873587 33 Q9Y624,P06756,P35613,P14543,Q08722,Q92542,P07237,P07942,P07858,P05067 10 +Metabolism of carbohydrates 0.3534371394850752 1.2288904405684309 0.2191128860702687 1.0 0.6935225942873587 96 P54802,O00462,Q9Y251,Q8TB61,P16278,P06865,Q9UBX3,P07686,P08236,P11166,O00754,Q7LGA3,Q9BTX1,O43505,P10253,P15586,Q9BRR6 17 +Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.7071170875696797 1.216078313163793 0.223955090991776 1.0 0.6955571243846478 4 P67812,Q15005,P61009 3 +Incretin synthesis secretion and inactivation 0.7071170875696797 1.216078313163793 0.223955090991776 1.0 0.6955571243846478 4 P67812,Q15005,P61009 3 +G alpha i signalling events 0.4536609579371238 1.2159386220463568 0.2240083040612088 1.0 0.6955571243846478 22 P10644,P17612,P04899,P07602,P05067,Q9NZJ7 6 +Bicarbonate transporters 0.8698787282858071 1.213854535779189 0.2248032766875438 1.0 0.695891032057219 2 P04920 1 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.6595497284950118 1.2099559907866242 0.2262957805665635 1.0 0.6979426914654373 5 O14654,P31751 2 +Metal ion slc transporters 0.8666011143887418 1.2004142039708166 0.2299785151499094 1.0 0.7001967134988535 2 Q8NEW0 1 +Zinc transporters 0.8666011143887418 1.2004142039708166 0.2299785151499094 1.0 0.7001967134988535 2 Q8NEW0 1 +Asparagine n linked glycosylation 0.3659045485986935 1.199049281565064 0.2305087836141266 1.0 0.7001967134988535 114 O43731,P04843,Q9BT22,P10619,Q99519,P62820,O00743,P54920,Q2TAA5,Q9BUN8,Q9UBV2,P24390,P27824,P04066,Q9H0U4,P53634,P14314,Q9Y5P6,Q14789,Q9Y6B6,P33908,P46977,P04350,P16278,Q9Y3B3,Q16706,P26572,Q9HCU5,P49755,O95249,Q13190,Q9BV10,Q12907,Q15363,Q13561,O75935 36 +Ldl remodeling 0.865617830219612 1.1963848052815462 0.2315464281132011 1.0 0.7001967134988535 2 P04114 1 +Vldl assembly 0.865617830219612 1.1963848052815462 0.2315464281132011 1.0 0.7001967134988535 2 P04114 1 +Interferon alpha beta signaling 0.5528535416416467 1.1953753253845816 0.2319404216968417 1.0 0.7001967134988535 9 P04439,P10321 2 +Synthesis of very long chain fatty acyl coas 0.5942099043838026 1.19528388966093 0.2319761319718907 1.0 0.7001967134988535 7 Q9NZ01,Q9P035 2 +Synthesis of pa 0.610832975914821 1.1925526235879074 0.2330446296711663 1.0 0.7001967134988535 6 Q8NF37,Q9NPH0,Q99943,P43304 4 +Vesicle mediated transport 0.4470186470444738 1.1863459572781143 0.2354857044649236 1.0 0.7009221929906809 242 O43731,P20339,O43633,O43493,O14657,Q9UPT5,Q9UNS2,O60499,Q9P2W9,Q9UIQ6,Q8TC07,P04114,P62820,O00743,P54920,P51148,Q9NP72,P05067,P51151,P40616,Q92572,P24390,P02786,P61020,P53634,Q9H0U4,P14672,O15511,Q10472,Q14789,P15586,Q9Y6B6,Q9UID3,P20645,P01130,P33908,O00115,Q8TBA6,Q9H0H5,Q9H9H4,P98164,P04350,Q15042,Q7Z6M1,Q9Y3B3,Q99523,Q16706,Q10471,P00533,Q14964,P49815,Q14108,Q9HCU5,Q9BT78,P49755,Q13190,O95249,O75976,P51809,O15260,Q8WTV0,Q99627,Q6NUQ1,P11717,Q07954,Q12907,Q15363,P51149,Q13561,Q5KU26,P11233,O00461,O75935,Q96CW1,P31751 75 +Adora2b mediated anti inflammatory cytokines production 0.5912918145588447 1.1806185602354395 0.2377542870526126 1.0 0.7045574580755225 7 P10644,P04899,P17612 3 +Autophagy 0.4352394163112011 1.168281329961521 0.242693303731261 1.0 0.7057865805796382 49 O43633,Q9NS69,Q9H9H4,Q6IAA8,Q13501,Q8N4H5,Q9Y4P8,O96008,P04350,Q9HB90,Q9Y4P1,P42345,Q8IWA4,Q15388,P49815,P21796,Q14596,P08670 18 +Plasma lipoprotein remodeling 0.7917594307881701 1.15480325026893 0.2481710058066868 1.0 0.711987217903463 3 P04114 1 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.6020451340391642 1.1497653778785226 0.2502405187198264 1.0 0.711987217903463 6 P07942 1 +Membrane trafficking 0.4401487078309645 1.1483794642316263 0.2508119474864068 1.0 0.711987217903463 234 O43731,P20339,O43633,O43493,O14657,Q9UPT5,Q9UNS2,O60499,Q9P2W9,Q9UIQ6,Q8TC07,P04114,P62820,O00743,P54920,P51148,Q9NP72,P05067,P51151,P40616,Q92572,P24390,P02786,P61020,P53634,Q9H0U4,P14672,O15511,Q10472,Q14789,P15586,Q9Y6B6,Q9UID3,P20645,P01130,P33908,O00115,Q8TBA6,Q9H0H5,Q9H9H4,P98164,P04350,Q15042,Q7Z6M1,Q9Y3B3,Q99523,Q16706,Q10471,P00533,Q14964,P49815,Q14108,Q9HCU5,Q9BT78,P49755,Q13190,O95249,O75976,P51809,O15260,Q6NUQ1,P11717,Q12907,Q15363,P51149,Q13561,Q99627,P11233,O00461,O75935,Q96CW1,P31751 72 +Vitamin c ascorbate metabolism 0.7884688890043796 1.141749180965813 0.2535582915451777 1.0 0.711987217903463 3 P11166 1 +Copi dependent golgi to er retrograde traffic 0.4363136113664667 1.140445057344014 0.2541009303375012 1.0 0.711987217903463 46 O43731,P35606,Q9H0H5,O75396,P24390,P04350,P49755,O15260,Q9P2W9,Q9Y3B3,Q9H0U4,Q6NUQ1,Q15363,P62820,Q86Y91,P54920,Q9Y678,P18085 18 +N glycan trimming and elongation in the cis golgi 0.8482464765650596 1.1254307109279535 0.260406563317535 1.0 0.7262809110161973 2 P33908 1 +Signaling by notch1 0.55896680723047 1.1194114257672991 0.2629646587769874 1.0 0.7262809110161973 8 Q96J02,Q9BZK7,Q92542 3 +Cytosolic sulfonation of small molecules 0.5956359422050174 1.1185367585791015 0.263337816284839 1.0 0.7262809110161973 6 Q8TB61 1 +Maturation of sars cov 1 spike protein 0.636574791577675 1.1059861712667922 0.2687325049160778 1.0 0.7298018950913705 5 P26572,P27824 2 +Pre notch processing in golgi 0.7793442622950724 1.1056056833272552 0.2688972288282261 1.0 0.7298018950913705 3 P16615,Q15363 2 +Er to golgi anterograde transport 0.3765376812076771 1.0976272145865118 0.2723673042163119 1.0 0.731711873960243 71 O43731,P62820,O00743,P54920,P35606,P24390,P53634,Q9H0U4,Q14789,Q9Y6B6,P49257,P04350,Q9Y3B3,Q9HCU5,Q9Y678,P49755,Q13190,O95249,Q12907,Q15363,Q13561,O75935,P18085 23 +Post translational modification synthesis of gpi anchored proteins 0.5531363236007469 1.0888804655174682 0.2762066016373086 1.0 0.7342667864136849 8 Q9H490,Q92643 2 +Mtorc1 mediated signalling 0.506712176198781 1.0848857268594028 0.2779722703547145 1.0 0.7361508218573536 11 P62942,Q9HB90,Q6IAA8,P42345 4 +Synthesis of pc 0.6303941405058934 1.0780248256245577 0.2810226773752817 1.0 0.7361508218573536 5 Q8NF37,Q9NQZ5,P35790 3 +Synthesis secretion and deacylation of ghrelin 0.7721311475409698 1.0770996728582196 0.281435739221012 1.0 0.7361508218573536 3 P67812,Q15005 2 +Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.7721311475409698 1.0770996728582196 0.281435739221012 1.0 0.7361508218573536 3 P67812,Q15005 2 +Heme signaling 0.5695374106555912 1.0711209203033736 0.2841150627685185 1.0 0.7370061125447789 7 P09601 1 +Syndecan interactions 0.6719366017795848 1.067955144854293 0.2855407456857437 1.0 0.738931698960112 4 P06756 1 +Attachment of gpi anchor to upar 0.6274143762790352 1.064549310337615 0.2870799287567878 1.0 0.7391910180373482 5 Q9H490,Q92643 2 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.5664447686412102 1.055540756981023 0.2911780794761132 1.0 0.7439599254168856 7 P31751 1 +Rhob gtpase cycle 0.433130538775306 1.055402627862798 0.2912412215474291 1.0 0.7439599254168856 23 Q9H0H5,P02786,O75955,P43121,Q8TAA9 5 +Molecules associated with elastic fibres 0.8289085545722863 1.0470706994726686 0.2950669718999519 1.0 0.7459678618087714 2 P06756 1 +Elastic fibre formation 0.8289085545722863 1.0470706994726686 0.2950669718999519 1.0 0.7459678618087714 2 P06756 1 +Glycogen breakdown glycogenolysis 0.578017158765637 1.0326539549077152 0.3017658687914217 1.0 0.7546855569595161 6 P10253 1 +Sensory perception 0.4299381197616668 1.0263705585649503 0.3047169501213354 1.0 0.7566322843476295 24 Q07954,P04114,P01130,P49356 4 +Regulation of insulin secretion 0.4955156160521951 1.0196134042777794 0.3079118452918283 1.0 0.7612197091751719 11 P10644,P11166,P17612 3 +Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.7573788609528871 1.0190187372822834 0.308194071131207 1.0 0.7612197091751719 3 Q9Y624 1 +Dna damage recognition in gg ner 0.4651671169070345 1.016698798415541 0.3092967375399478 1.0 0.7612197091751719 15 Q99627,P41208,Q9BT78 3 +Negative regulators of ddx58 ifih1 signaling 0.5382114865188876 1.010670216427024 0.3121742965604115 1.0 0.7647561091094776 8 Q86VP1 1 +Amino acids regulate mtorc1 0.493443509610046 1.0075252224675195 0.3136824432221861 1.0 0.7647561091094776 11 Q9HB90,Q6IAA8,P42345,P36543 4 +Met activates ptk2 signaling 0.6137315063388873 1.0027369399128907 0.3159878017572803 1.0 0.7647561091094776 5 P07942 1 +Intrinsic pathway of fibrin clot formation 0.8177646673221884 1.0022867931767432 0.3162050992254879 1.0 0.7647561091094776 2 Q07021 1 +Hemostasis 0.3527260744724697 0.9882556260992034 0.3230274715165393 1.0 0.7700464512792394 117 P20339,Q9UNN8,Q9Y6I9,P05556,Q08722,P04114,Q6UXV4,P07602,P05067,Q08380,P17612,O94919,Q07021,P42785,Q13685,P20020,O43852,P10644,Q9H0H5,P06756,P04350,Q92520,Q9NUQ9,P08195,Q06481,P16615,Q8IWA4,Q96JJ7,Q9NZJ7,Q9Y624,P54709,P35613,Q8NBX0,Q92896,Q9H4M9 35 +Glucagon like peptide 1 glp1 regulates insulin secretion 0.6500121794019793 0.9760854766236504 0.3290221078348572 1.0 0.7720058519329988 4 P10644 1 +Signalling to ras 0.7451595664149214 0.9711806593724358 0.3314583231976544 1.0 0.7720058519329988 3 P11233 1 +Rnd2 gtpase cycle 0.4578026278497853 0.9686192024902484 0.3327352188803476 1.0 0.7720058519329988 15 Q8TAA9,P02786,P51648 3 +Signal transduction by l1 0.4852201720947851 0.9595408123254896 0.3372863698302653 1.0 0.7720058519329988 11 P06756,O14786,P00533 3 +N glycan antennae elongation in the medial trans golgi 0.8069485414618404 0.9591291650345852 0.3374936795134236 1.0 0.7720058519329988 2 P04066 1 +Reactions specific to the complex n glycan synthesis pathway 0.8069485414618404 0.9591291650345852 0.3374936795134236 1.0 0.7720058519329988 2 P04066 1 +Ion transport by p type atpases 0.5095083766354207 0.9590965742180392 0.3375100960712105 1.0 0.7720058519329988 9 P16615,Q04656,P05023,Q9HD20,P20020 5 +Regulation of mecp2 expression and activity 0.4900644917242789 0.9553806719450452 0.3393852246455839 1.0 0.7737538755013068 10 Q9HCE1,Q14739,P17612 3 +Ros and rns production in phagocytes 0.5271014564088347 0.9524542344055418 0.3408666655347772 1.0 0.7745958647470549 8 Q93050,P36543,Q9Y487 3 +Rhoq gtpase cycle 0.4156844183616218 0.9482215558193644 0.3430166756475872 1.0 0.7759960883681369 19 Q6IAA8,P02786,Q9Y6M7,Q8TAA9,P51149 5 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.6395304111292421 0.9323852089106298 0.3511374860043981 1.0 0.7797813798686457 4 Q8NB78,Q9HCE1 2 +Cd28 dependent pi3k akt signaling 0.734566525227432 0.9299483807181024 0.3523978115878674 1.0 0.7797813798686457 3 P31751 1 +Cdc42 gtpase cycle 0.4192086046488459 0.9289695449838 0.3529048696405099 1.0 0.7797813798686457 28 Q9H0H5,P42167,Q6IAA8,Q9UQB8,P02786,Q14739,Q8TAA9,P51149 8 +Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.6382634718385796 0.9271153909633169 0.3538666258842475 1.0 0.7797813798686457 4 P17612 1 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.5034130004884613 0.9258357613357384 0.3545313393722318 1.0 0.7797813798686457 9 O60725,P38435 2 +Nod1 2 signaling pathway 0.5406773866733929 0.9258059140016984 0.3545468532049531 1.0 0.7797813798686457 7 Q96J02 1 +N glycan trimming in the er and calnexin calreticulin cycle 0.4630967110679774 0.9040170553173704 0.3659863578106428 1.0 0.7809372435712464 13 P27824,Q9BUN8,Q9UBV2 3 +Nr1h2 and nr1h3 mediated signaling 0.5503533897430565 0.898051583401303 0.3691580495353941 1.0 0.7809372435712464 6 Q8NB78,Q9HCE1 2 +Thromboxane signalling through tp receptor 0.7902327105867084 0.8931264991745852 0.3717894335741123 1.0 0.7809372435712464 2 Q13685 1 +Golgi to er retrograde transport 0.3662674534566192 0.8796717277003533 0.3790371695168801 1.0 0.7809372435712464 68 O43731,Q9H0H5,P49755,P24390,P04350,Q15042,O15260,Q9P2W9,Q9Y3B3,Q9H0U4,Q10471,Q6NUQ1,Q10472,P62820,Q15363,Q13561,P54920,O75935 18 +Adenylate cyclase inhibitory pathway 0.719016393442611 0.869900451697827 0.3843548086015129 1.0 0.7809372435712464 3 P04899,P08754 2 +Adp signalling through p2y purinoceptor 12 0.719016393442611 0.869900451697827 0.3843548086015129 1.0 0.7809372435712464 3 P04899,P08754 2 +Gaba receptor activation 0.719016393442611 0.869900451697827 0.3843548086015129 1.0 0.7809372435712464 3 P04899,P08754 2 +Gaba b receptor activation 0.719016393442611 0.869900451697827 0.3843548086015129 1.0 0.7809372435712464 3 P04899,P08754 2 +Alpha oxidation of phytanate 0.6231697996483945 0.8645744412799157 0.3872724058093237 1.0 0.7809372435712464 4 P51648 1 +Complex i biogenesis 0.4096258153016124 0.8568487669574243 0.3915284701943444 1.0 0.7809372435712464 27 O96000,Q9Y6M9,Q9P0J0,Q86Y39,O43676,P03886,O75438,P03915 8 +Rac1 gtpase cycle 0.4089362377953443 0.8548747695947612 0.3926204796384118 1.0 0.7809372435712464 40 Q14344,Q9H0H5,Q6IAA8,P42167,P02786,Q9UQB8,Q14739,Q15758,P05556,P43121,Q8TAA9,P51149,Q16513,P50402 14 +Synthesis of pips at the golgi membrane 0.5262391517365076 0.8533399400703988 0.3934708173079015 1.0 0.7809372435712464 7 Q9UBF8,Q9BTU6 2 +Beta catenin phosphorylation cascade 0.539075813227886 0.8434239891422038 0.3989913600907044 1.0 0.7809372435712464 6 P48729,P30154 2 +Signaling by ctnnb1 phospho site mutants 0.539075813227886 0.8434239891422038 0.3989913600907044 1.0 0.7809372435712464 6 P48729,P30154 2 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.5390758132278858 0.843423989142203 0.3989913600907049 1.0 0.7809372435712464 6 P48729,P30154 2 +Aquaporin mediated transport 0.6165899061945411 0.8374694658180033 0.4023287332421814 1.0 0.7809372435712464 4 P10644,P17612 2 +Ra biosynthesis pathway 0.7091803278688319 0.832260338598832 0.4052620122826824 1.0 0.7812051000278988 3 Q8NBN7,Q8TC12 2 +P38mapk events 0.7725335955424651 0.8243247728644154 0.4097550462594408 1.0 0.7856264333132535 2 P11233 1 +Unfolded protein response upr 0.4061623470412935 0.8238678376723865 0.4100146568691567 1.0 0.7856264333132535 38 O43731,Q9Y5M8,P43307,O95070,O76024,O14773,Q9HCU5 7 +Copi mediated anterograde transport 0.3960329520680462 0.8198447917524873 0.4123045927893245 1.0 0.7867675311719576 50 O43731,Q13190,O95249,P24390,P04350,Q9Y3B3,Q9H0U4,Q14789,Q15363,P62820,Q13561,O75935 12 +Rhof gtpase cycle 0.3982522709741034 0.8176565526249278 0.4135533257665591 1.0 0.7869942387880012 19 P42167,Q8TAA9,P43121,Q9Y6M7 4 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.4949344576900835 0.7845277049374402 0.4327305320081778 1.0 0.8012281388023212 8 P30260,Q9UJX4,Q9UJX3,Q96DE5,Q12834 5 +Neuronal system 0.3929486172316609 0.7801566944136523 0.4352986488998265 1.0 0.8012281388023212 49 P10644,Q96QD8,P21964,P17612,P04350,P10586,O95197,O75955,O75915,P08754,Q14254,P04899,P07196 13 +Diseases associated with glycosylation precursor biosynthesis 0.493755598428757 0.7784067940779635 0.4363292347365504 1.0 0.8012281388023212 8 P16278,P10619 2 +Glucagon signaling in metabolic regulation 0.6930470702672666 0.7711986418840311 0.4405891990829707 1.0 0.8012281388023212 3 P10644 1 +Vasopressin regulates renal water homeostasis via aquaporins 0.6930470702672666 0.7711986418840311 0.4405891990829707 1.0 0.8012281388023212 3 P10644 1 +Creb1 phosphorylation through the activation of adenylate cyclase 0.6930470702672666 0.7711986418840311 0.4405891990829707 1.0 0.8012281388023212 3 P10644 1 +Pka mediated phosphorylation of creb 0.6930470702672666 0.7711986418840311 0.4405891990829707 1.0 0.8012281388023212 3 P10644 1 +Pka activation in glucagon signalling 0.6930470702672666 0.7711986418840311 0.4405891990829707 1.0 0.8012281388023212 3 P10644 1 +Miscellaneous transport and binding events 0.5142751111672509 0.7242430987527575 0.4689165033342164 1.0 0.8331641443170452 6 Q8N4V1 1 +Ras processing 0.5492170821599924 0.7151671619426417 0.4745057575273215 1.0 0.8420035583640987 5 P49356 1 +Translocation of slc2a4 glut4 to the plasma membrane 0.3929419718160962 0.7114261754218293 0.4768201833786791 1.0 0.8439777832865312 32 Q9UIQ6,P11233,P31751 3 +Miro gtpase cycle 0.5848591443774216 0.7085506356452341 0.4786033791175836 1.0 0.8460590191761346 4 Q8IWA4 1 +G protein mediated events 0.4410580779068545 0.7028137226472395 0.4821718441855247 1.0 0.8502093404435899 11 P10644,P17612,P08754,P04899,P52292,P63096 6 +Anti inflammatory response favouring leishmania parasite infection 0.4452451906276188 0.7012905865615989 0.4831216871658033 1.0 0.8508072189911049 10 P10644,P04899,P17612 3 +Downregulation of erbb2 signaling 0.4755730591973248 0.6844890392115948 0.4936664083402893 1.0 0.860076937593782 8 P31751 1 +Signaling by notch3 0.4894884946471711 0.6708399595410935 0.5023224882932746 1.0 0.863398596406271 7 Q92542 1 +Rnd3 gtpase cycle 0.4107707778753945 0.6627957912306685 0.5074613495316167 1.0 0.8673541839233645 15 Q14254,O75976,Q8TAA9,Q07065 4 +Apc c cdc20 mediated degradation of cyclin b 0.4379801591473926 0.660537235022641 0.5089091319276617 1.0 0.8687627705578833 10 P30260,Q9UJX4,Q9UJX3,Q96DE5,Q12834 5 +Chl1 interactions 0.6604931451287968 0.6511501932992226 0.5149495381468618 1.0 0.874081115350221 3 O14786 1 +Respiratory electron transport 0.3767064703143592 0.6508211440507434 0.5151619495351984 1.0 0.874081115350221 51 O14949,P13073,O96000,Q9Y6M9,P00403,Q9P0J0,Q86Y39,Q9UDW1,O43676,Q15526,P03886,O75438,O95169,P03915 14 +Fcgr3a mediated il10 synthesis 0.530172457535807 0.6326430119081077 0.5269667924063237 1.0 0.8770556626700932 5 P10644 1 +Signaling by notch1 pest domain mutants in cancer 0.4816790838997293 0.6326342466594548 0.5269725176649112 1.0 0.8770556626700932 7 Q9BZK7,Q92542 2 +Glutamate neurotransmitter release cycle 0.6537030371341039 0.6267492834790475 0.5308235929386347 1.0 0.8798795178606484 3 Q96QD8 1 +Adrenaline noradrenaline inhibits insulin secretion 0.7187807276302822 0.624502884355357 0.5322973766773393 1.0 0.8798795178606484 2 P04899 1 +Activation of nmda receptors and postsynaptic events 0.3743493795399621 0.6226302050314723 0.533527557463422 1.0 0.8798795178606484 21 P10644,P17612,Q92796,P04350,Q14168,P52292,P07196,Q9BUF5 8 +Metabolism of lipids 0.3636850986947122 0.6223088062689374 0.533738831724514 1.0 0.8798795178606484 170 Q15392,P20339,Q5T8D3,Q96N66,P10619,Q8IV08,Q9UMR5,Q9Y6X9,Q9NTJ5,O95470,Q99519,Q9BTU6,P07602,Q9NQZ5,Q14534,P04062,O43808,P17612,Q8NCC3,Q15067,Q9UG56,P06280,Q16850,P35610,Q14849,Q9NPH0,Q53GQ0,P50897,Q9Y6B6,Q53H12,Q13510,Q8NF37,P98164,P16278,P06865,Q99538,Q06136,Q96G23,Q15800,Q8TCT0,P07686,P09960,O14735,Q9H2C2,P17900,P35790,P23786,P27544,Q9BZK7,Q9NZJ7,Q14739,Q9P035,Q15165,P14324,P38435,Q06520,P48651,P51648,Q16739,Q9UBF8,O15269,Q9NZ01,O95772 63 +Striated muscle contraction 0.5623867087262396 0.6196153316823436 0.5355110704146377 1.0 0.8807165538224208 4 P28289,P08670 2 +Activation of ampk downstream of nmdars 0.4886773875943623 0.6033890978648769 0.5462498731287617 1.0 0.8889323285845387 6 P04350,Q9BVA1,Q9BUF5,P54619,P68371 5 +Prevention of phagosomal lysosomal fusion 0.6456593643621257 0.5981725394912386 0.5497248123749832 1.0 0.8893921761188752 3 P51149 1 +Cell cell junction organization 0.4581425531374338 0.5956101345503552 0.5514357047389598 1.0 0.8903194936100822 8 Q9Y624,P19022 2 +Wax and plasmalogen biosynthesis 0.5546080682190766 0.5894151984866989 0.555582783502931 1.0 0.8939691717331827 4 O00116,Q6IAN0,Q8WVX9 3 +Inla mediated entry of listeria monocytogenes into host cells 0.7066535562110734 0.5818313405547648 0.5606802915293678 1.0 0.8976759902560674 2 O60716 1 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.3676090890784742 0.581117290072484 0.5611614064235972 1.0 0.8976759902560674 20 Q9BV10,P16278,Q9BT22,P10619,Q99519 5 +Regulated necrosis 0.3663526231701473 0.5809277465504332 0.5612891511220637 1.0 0.8976759902560674 19 O43633,Q8WUM4,O75955,O00560,Q9Y3E7,Q14254,Q9UNE7 7 +Camk iv mediated phosphorylation of creb 0.7033759423139905 0.5704798378927001 0.5683522932158955 1.0 0.8993373837832134 2 P52292 1 +Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.7033759423139905 0.5704798378927001 0.5683522932158955 1.0 0.8993373837832134 2 P52292 1 +Phosphorylation of emi1 0.5457527058051586 0.5554560826772882 0.5785827414084128 1.0 0.9033248659186428 4 P53350,Q12834,P14635 3 +Fatty acyl coa biosynthesis 0.3933718531215328 0.5516015139455278 0.58122139895041 1.0 0.9033248659186428 15 Q9P035,Q9UMR5,Q9Y6X9,P50897,Q53GQ0,Q9NZ01 6 +Calnexin calreticulin cycle 0.4640279400912163 0.5473731246691854 0.5841224151958992 1.0 0.9040916937420972 7 P27824,Q9UBV2 2 +Platelet calcium homeostasis 0.6289657595942091 0.540111435229674 0.5891201849973542 1.0 0.9077491706903308 3 P16615 1 +Reduction of cytosolic ca levels 0.6289657595942091 0.540111435229674 0.5891201849973542 1.0 0.9077491706903308 3 P16615 1 +Negative regulation of the pi3k akt network 0.4031163806137432 0.5392074531147133 0.5897437182159004 1.0 0.9077491706903308 13 P31751 1 +Bmal1 clock npas2 activates circadian gene expression 0.5380704918383289 0.5263910889804934 0.5986165057902473 1.0 0.9107743905961002 4 P43490 1 +Golgi cisternae pericentriolar stack reorganization 0.4080871387225339 0.5151384668369617 0.6064562641013924 1.0 0.9107743905961002 11 P62820,Q9H0U4,O95067 3 +G1 s specific transcription 0.4264493452454292 0.5128235388794826 0.6080747625155807 1.0 0.9117848699507038 9 P00374,Q9Y619 2 +G alpha s signalling events 0.5332903792299929 0.5085048628019331 0.6110993296997567 1.0 0.914351628648508 4 P04899,P08754 2 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.346906668645807 0.4845674177551633 0.6279832306379218 1.0 0.9286418686609608 60 O14949,P13073,O75964,O96000,Q9Y6M9,P00403,Q9P0J0,Q86Y39,Q9UDW1,O43676,Q15526,P03886,O75438,O95169,P03915 15 +Ca dependent events 0.4480378952905395 0.471776270165362 0.6370864904439864 1.0 0.9361408029414272 7 P10644,P17612,P52292 3 +Activation of kainate receptors upon glutamate binding 0.6712553261225769 0.4637983353282158 0.6427922361231542 1.0 0.936722515374026 2 Q92796 1 +Ionotropic activity of kainate receptors 0.6712553261225769 0.4637983353282158 0.6427922361231542 1.0 0.936722515374026 2 Q92796 1 +Nrcam interactions 0.6712553261225769 0.4637983353282158 0.6427922361231542 1.0 0.936722515374026 2 Q92796 1 +Polo like kinase mediated events 0.6052640100058274 0.4609674507531565 0.6448219577387015 1.0 0.936722515374026 3 O95067 1 +Gap junction assembly 0.488517060367466 0.4590138515743072 0.6462242191489154 1.0 0.936722515374026 5 Q9BVA1,P68371,Q9BUF5,P04350 4 +Transport of connexons to the plasma membrane 0.488517060367466 0.4590138515743072 0.6462242191489154 1.0 0.936722515374026 5 Q9BVA1,P68371,Q9BUF5,P04350 4 +Translation of sars cov 2 structural proteins 0.3573000748524228 0.456034147961915 0.6483654227178168 1.0 0.9372652472605194 18 P04843,P27824,P48729,P14314,Q16706,P26572,Q10472,P46977 8 +Myogenesis 0.4809592142700263 0.4288356569624342 0.6680428278577655 1.0 0.9497867051796188 5 O60271,P19022 2 +Initiation of nuclear envelope ne reformation 0.3607150265598138 0.4286311786108588 0.6681916518851589 1.0 0.9497867051796188 17 Q86XL3,P42167,Q14739,P50402 4 +Suppression of phagosomal maturation 0.4496261029385915 0.4260396730730746 0.6700789375319647 1.0 0.950529490816728 6 P51149 1 +Cell cell communication 0.3534591703256455 0.4236193955538437 0.6718434079372231 1.0 0.950800401075612 27 Q9Y624,P19022,Q08722,Q96J84,Q92692 5 +Ptk6 regulates proteins involved in rna processing 0.658144870534245 0.4228938504248273 0.6723727097582533 1.0 0.950800401075612 2 Q07666 1 +Pi metabolism 0.3823925457731479 0.4177174586425986 0.6761537060831961 1.0 0.950800401075612 13 P20339,Q9NTJ5,Q9BTU6,Q9UBF8,Q10713,P48739 6 +Cytochrome p450 arranged by substrate type 0.5796939877016007 0.3806704672405708 0.7034477855494348 1.0 0.9665384254259248 3 P16435 1 +Free fatty acids regulate insulin secretion 0.6424123238282461 0.3760752841878694 0.7068609282138141 1.0 0.9665384254259248 2 O60488 1 +Apoptotic factor mediated response 0.4360059585111146 0.3670328719312865 0.7135944982949929 1.0 0.9715376615761604 6 Q07021 1 +Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.4625984251968551 0.3576646881245136 0.7205942620437746 1.0 0.9727126543673156 5 Q13546,Q7Z434,O14920,Q14258 4 +Phosphorylation of the apc c 0.3820798903015868 0.357374599427063 0.7208113896495916 1.0 0.9727126543673156 10 P30260,Q9UJX4,Q9UJX3,P53350,Q96DE5 5 +Pyruvate metabolism 0.3664880102515816 0.3531808616917972 0.7239528547115079 1.0 0.9727126543673156 14 P09622,P21796 2 +Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.4204461720752344 0.3462563564250073 0.7291500647418605 1.0 0.9727126543673156 7 P30260,Q9UJX4,Q9UJX3,Q96DE5 4 +Rhoh gtpase cycle 0.3374880526744792 0.3450601583847522 0.7300491449822979 1.0 0.9727126543673156 22 Q6IAA8,P02786,Q9Y6M7,Q9BXS4,Q8TAA9 5 +Cd28 co stimulation 0.3931687960796903 0.3445837174442916 0.7304073485055365 1.0 0.9727126543673156 9 P31751 1 +Opioid signalling 0.3455901980079885 0.3303885302650803 0.7411064069515669 1.0 0.9797330140699878 17 P10644,P17612,Q13555,P08754,P04899,P52292,P63096,P30154 8 +Signaling by retinoic acid 0.3874360692388326 0.3167524635658144 0.7514314367343198 1.0 0.9797330140699878 9 P09622 1 +Dna damage reversal 0.4765496884224252 0.3106372792450967 0.756076383526967 1.0 0.9797330140699878 4 Q6P6C2,Q9C0B1,Q9H1I8 3 +Transcriptional regulation by ventx 0.3662043846483869 0.305238035373756 0.7601848657332289 1.0 0.9797330140699878 12 P35222,P30260,Q9UJX4,Q9UJX3,Q96DE5,Q9HCE1 6 +Slc transporter disorders 0.3425623030468656 0.3046601363146001 0.7606250136643664 1.0 0.9797330140699878 35 P35613,P08195,P11166,Q92581,Q9BTX1 5 +Association of tric cct with target proteins during biosynthesis 0.3344441259046028 0.3020627602770386 0.7626042202044792 1.0 0.9797330140699878 18 P04062,O95302 2 +Platelet activation signaling and aggregation 0.3395253532596154 0.3009906606354366 0.7634216162324932 1.0 0.9797330140699878 50 Q08380,O94919,Q9NZJ7,Q8NBX0,Q9NUQ9,Q06481,Q13685,P07602,Q96JJ7,P05067,O43852 11 +Metabolism of steroids 0.3417379900994807 0.2925868302007192 0.7698379814393899 1.0 0.9805549693910052 43 Q15392,P04062,Q14739,P98164,Q99538,Q15800,Q16850,P38435,Q14849,Q53GQ0,Q9H2C2,Q9Y6B6,O95772,Q9BZK7,Q14534 15 +Leishmania infection 0.3403215616787733 0.2824583838439862 0.777592052763292 1.0 0.9805549693910052 37 P10644,Q9UQB8,P17612,P09601,Q96JJ3,O15511,P04899,P05067 8 +Darpp 32 events 0.3774602314466391 0.2693218893083232 0.7876819890513531 1.0 0.9805549693910052 9 P10644,P17612 2 +Synthesis of pips at the plasma membrane 0.4022349141590288 0.2678335827490798 0.7888274194928064 1.0 0.981104102994178 7 Q9BTU6 1 +Intrinsic pathway for apoptosis 0.3287310820034153 0.2649154863088858 0.7910745680870124 1.0 0.9813622454342436 18 Q07021,P31751 2 +G alpha z signalling events 0.4618918694471153 0.2648195733144472 0.7911484577334211 1.0 0.9813622454342436 4 P04899,P08754 2 +Pp2a mediated dephosphorylation of key metabolic factors 0.5354098360655793 0.2567479115260105 0.7973733828946643 1.0 0.987484729040388 3 P30154,Q14738 2 +Sars cov 2 infection 0.3268434272084228 0.2531852123013061 0.8001250931950545 1.0 0.987484729040388 24 O43633,P04843,P27824,P48729,P14314,Q16706,P26572,Q10472,P46977,Q9H0U3 10 +Intraflagellar transport 0.3737108182389768 0.2518510617889308 0.8011561874710278 1.0 0.987484729040388 9 A0AVF1,Q92973 2 +Anchoring of the basal body to the plasma membrane 0.3320988551673334 0.2423965129685691 0.8084729360748848 1.0 0.9898885406776926 31 P04350,P17612,O94927,Q15154,P41208,Q13561,O75935 7 +Neurotransmitter receptors and postsynaptic signal transmission 0.3314276948603549 0.2374945820164369 0.8122731219128614 1.0 0.9925407533549264 31 P10644,P17612,Q92796,P04350,Q96CW1,Q14168,P08754,P04899,P52292,P07196,P63096,Q9BUF5 12 +Apoptotic cleavage of cell adhesion proteins 0.394101670052233 0.234192409194208 0.8148356077663259 1.0 0.9939281975643536 7 Q16625 1 +Antigen processing cross presentation 0.3299782396156218 0.2290858292174432 0.8188022072642345 1.0 0.9963991432358466 52 P06756,P10321,P49721,P01889,Q9UBG0,Q9UIQ6,P04439,Q03518,P60900 9 +Glycogen metabolism 0.3674599919680572 0.2231922103002186 0.8233859143226168 1.0 0.9965044123817596 9 P10253 1 +Tnfr1 induced nfkappab signaling pathway 0.3987528716770623 0.2162538971431278 0.8287898434881207 1.0 1.0 6 O15111,Q6GQQ9,Q15750,Q13546,O14920 5 +Nef and signal transduction 0.576204523107169 0.2102250918816498 0.8334919966316399 1.0 1.0 2 P63000 1 +Dag and ip3 signaling 0.3876539042816775 0.208198762981297 0.835073774426135 1.0 1.0 7 P10644 1 +Mitochondrial biogenesis 0.3263114059918363 0.206238197589744 0.8366048517816105 1.0 1.0 30 Q16891,Q9NVH1,O75964,Q9BUR5,Q9Y512,Q6UXV4,P56134,Q13505,Q5XKP0 9 +Dap12 signaling 0.5735824319895025 0.2047900260086076 0.8377361799590712 1.0 1.0 2 P63000 1 +Cholesterol biosynthesis 0.3344901406095359 0.1979092189885653 0.8431160911342945 1.0 1.0 15 Q15392,Q14739,Q15800,Q16850,Q9H2C2,Q14534 6 +Activation of nima kinases nek9 nek6 nek7 0.4160104986876729 0.1940813228535851 0.8461122057687169 1.0 1.0 5 P53350,P06493,P14635,O95067 4 +Potential therapeutics for sars 0.3290584338428193 0.1933148097754267 0.8467124285651555 1.0 1.0 38 P54709,P21964,P62942,P05023,P05556,Q99720,P15260,Q96CW1,P49356 9 +Signaling by ptk6 0.3378896680336729 0.1932853464184816 0.8467355018059992 1.0 1.0 14 Q96JJ3 1 +Budding and maturation of hiv virion 0.3432087676928047 0.1863545321824335 0.8521667458530053 1.0 1.0 12 O43633,Q9H9H4,Q8WUM4,Q9Y3E7,Q96PU5 5 +Pre notch expression and processing 0.3569188357459057 0.1762923922717684 0.8600642385210422 1.0 1.0 9 P16615,Q9HCE1 2 +Tnfr1 induced proapoptotic signaling 0.5565388397246737 0.1716768964635143 0.8636915500731488 1.0 1.0 2 Q13546 1 +Signaling by erbb2 0.3383601392295291 0.1624890087117913 0.8709207830353585 1.0 1.0 12 P31751 1 +Notch1 intracellular domain regulates transcription 0.3833278634722622 0.1594487030895492 0.8733153701706495 1.0 1.0 6 Q13573,Q13616,Q13547,P63208,Q9BZK7 5 +Signaling by gpcr 0.3252163577640229 0.1585089068650558 0.8740558027266636 1.0 1.0 43 P10644,P42892,P48960,P00533,P07602,P05067,P31751 7 +Metabolism of folate and pterines 0.362681964272679 0.1534591092909994 0.8780362343577566 1.0 1.0 8 Q9H2D1 1 +Role of lat2 ntal lab on calcium mobilization 0.5447394296951732 0.1510096575553409 0.8799680976383706 1.0 1.0 2 P62993 1 +Peroxisomal lipid metabolism 0.3394461951379813 0.1493197281083683 0.8813013490033115 1.0 1.0 10 Q15067,O43808,P51648 3 +Signaling by egfr 0.3373490828354784 0.139881513925693 0.8887536074242672 1.0 1.0 10 Q13685 1 +Interleukin 15 signaling 0.5375286791215899 0.1392858221252771 0.8892242929759671 1.0 1.0 2 P62993 1 +Regulation of tp53 expression and degradation 0.3353057199211028 0.137592073362944 0.8905628204823293 1.0 1.0 11 P04637,P30153,P06493,P42345,P20248,P31749,P24941,P30154,Q93009,P31751 10 +Sars cov infections 0.3090268275489347 0.1338617259341487 0.8935119161096705 1.0 1.0 62 O43633,P04843,P62942,P05023,P05556,Q14145,P15260,P27824,Q99720,P14314,Q10472,P46977,P49356,P48729,Q16706,P26572,P54709,P21964,Q96CW1 19 +Cyclin d associated events in g1 0.3573070607553436 0.1322194719111376 0.8948106999757188 1.0 1.0 8 P11802,P30153,P07948,Q13616,P24941,P63208,P30154 7 +Organelle biogenesis and maintenance 0.2645195836658015 0.132060477645867 0.8949364563243631 1.0 1.0 84 O75964,Q9BUR5,Q9Y512,Q15154,Q6UXV4,Q13505,A0AVF1,Q16891,P17612,A6NIH7,Q9NVH1,P04350,Q92973,P56134,Q9BZK7,O94927,P41208,Q13561,O75935,Q5XKP0 20 +Rho gtpase cycle 0.31214153037106 0.1259914051888364 0.8997387280256066 1.0 1.0 148 Q6IAA8,Q9Y6M7,Q14126,O15173,Q13505,P30519,P02786,Q07021,Q8NBN3,Q9BXS4,Q8TAA9,Q07065,Q9H0H5,P42167,Q96JJ3,Q15904,Q9BT78,Q96HY6,Q13190,O75976,Q14739,O75955,P43121,Q86XL3,P51648,O95202 26 +Atf6 atf6 alpha activates chaperones 0.5270403146509236 0.123447297538752 0.9017529054449328 1.0 1.0 2 P14625 1 +Atf6 atf6 alpha activates chaperone genes 0.5270403146509236 0.123447297538752 0.9017529054449328 1.0 1.0 2 P14625 1 +Rhot1 gtpase cycle 0.5257292690920908 0.121567648107036 0.9032414364766004 1.0 1.0 2 P52306 1 +Signaling by vegf 0.3124120495411107 0.109536303362589 0.912777129069194 1.0 1.0 30 P06756,P17612,Q96JJ3,P42345,Q13685,O14786,P31751 7 +Dcc mediated attractive signaling 0.4017710724827653 0.1065510635902752 0.915145143073425 1.0 1.0 4 P16333,P63000,Q05397 3 +Diseases of mitotic cell cycle 0.3397493218442101 0.104218492739512 0.9169959588018188 1.0 1.0 9 P30260,Q9UJX4,Q9UJX3,Q96DE5 4 +Josephin domain dubs 0.5126188135037582 0.1039733153714564 0.9171905250214848 1.0 1.0 2 P54727 1 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.510324483775801 0.1011156715686448 0.9194586376947947 1.0 1.0 2 P11802 1 +Ptk6 regulates cell cycle 0.510324483775801 0.1011156715686448 0.9194586376947947 1.0 1.0 2 P11802 1 +Ngf stimulated transcription 0.4508196721311422 0.0857861040032869 0.9316364531521396 1.0 1.0 3 Q00535,P50570 2 +Postmitotic nuclear pore complex npc reformation 0.2998425761169689 0.0842459753602472 0.9328608650350284 1.0 1.0 23 Q8N1F7,Q92621,Q8NFH4,Q92973,Q9BTX1 5 +Depolymerisation of the nuclear lamina 0.3332352903134883 0.078428340148863 0.9374873307771444 1.0 1.0 9 P42167 1 +Er quality control compartment erqc 0.4854146181579689 0.074139585640137 0.9408993171318248 1.0 1.0 2 Q9UBV2 1 +Notch hlh transcription pathway 0.3830764184978685 0.0682749769821552 0.9455667431131528 1.0 1.0 4 Q13573,Q9BZK7,Q13547 3 +Maturation of sars cov 2 nucleoprotein 0.3707349081364871 0.0654368282083526 0.947826202232218 1.0 1.0 5 P48729,P78362,P49840,Q96SB4 4 +Transmission across chemical synapses 0.3116246603641918 0.0641803798706172 0.948826599776641 1.0 1.0 38 P10644,Q96QD8,P21964,P17612,Q92796,P04350,Q96CW1,O75915,Q14168,P08754,P04899,P52292,P07196,Q9BUF5 14 +Adherens junctions interactions 0.3480482358378862 0.0638737765938865 0.9490707328755196 1.0 1.0 7 Q92692,O60716,P19022 3 +Aflatoxin activation and detoxification 0.4347083448611313 0.0638016334568836 0.9491281776004736 1.0 1.0 3 Q99735 1 +Synthesis of ip2 ip and ins in the cytosol 0.4660766961651876 0.0579540416164666 0.9537852364355308 1.0 1.0 2 Q01968 1 +Cyclin a b1 b2 associated events during g2 m transition 0.3172255095331993 0.0577988382782091 0.9539088635535136 1.0 1.0 11 O95067,P53350,P63151,P06493,P30153,P14635,P20248,P24941,Q9Y570,P30154 10 +Ikba variant leads to eda id 0.4621435594886796 0.0551254541135315 0.95603851752279 1.0 1.0 2 O14920 1 +Loss of function of mecp2 in rett syndrome 0.3654734484762512 0.0527606517559223 0.9579226131591628 1.0 1.0 5 P17612 1 +Interactions of vpr with host cellular proteins 0.3067518656000466 0.047626696052929 0.9620137557933064 1.0 1.0 34 Q9BTX1,P12235,Q8NFH4,P12236 4 +Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.4503441494591832 0.0475044159180791 0.9621112109173172 1.0 1.0 2 O00767 1 +Caspase activation via death receptors in the presence of ligand 0.4503441494591806 0.0475044159180774 0.9621112109173188 1.0 1.0 2 Q13546 1 +Regulation by c flip 0.4503441494591806 0.0475044159180774 0.9621112109173188 1.0 1.0 2 Q13546 1 +Mhc class ii antigen presentation 0.309420721942519 0.0465323012801653 0.9628859892629348 1.0 1.0 51 Q9H0H5,P27824,Q99538,P53634,P10619,Q13561,Q9Y6B6,P51149,P07858 9 +Response of eif2ak1 hri to heme deficiency 0.4193442622950779 0.0458706889117419 0.96341331643635 1.0 1.0 3 P05198,P20042 2 +Transcriptional regulation by mecp2 0.307115257825478 0.0399136613624383 0.9681619595904492 1.0 1.0 14 Q9HCE1,Q14739,P17612 3 +Assembly of the hiv virion 0.4023365338246168 0.0292832755059251 0.9766386653956716 1.0 1.0 3 Q9H9H4 1 +Fbxw7 mutants and notch1 in cancer 0.3854473942969429 0.023826990633872 0.9809906107456374 1.0 1.0 2 P63208 1 +Regulation of bach1 activity 0.3854473942969429 0.023826990633872 0.9809906107456374 1.0 1.0 2 P63208 1 +Transcriptional regulation of white adipocyte differentiation 0.304898282335723 0.0193221784387238 0.9845840913947574 1.0 1.0 13 Q9NVC6,Q9BZK7,P14672 3 +Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.3235004916420773 0.0177233407767001 0.9858595603239282 1.0 1.0 2 P18887 1 +Regulation of tp53 activity through methylation 0.3347554972103627 0.008218680092887 0.993442515866529 1.0 1.0 6 Q9H9B1,Q9NRG4,P04637,O14744,Q96KQ7 5 +Recruitment of mitotic centrosome proteins and complexes 0.2994725139689342 0.0051909018493209 0.9958582781578936 1.0 1.0 33 P04350,P17612,O94927,Q15154,P41208,Q13561,O75935 7 +Constitutive signaling by overexpressed erbb2 0.3665573770491768 0.0043028344675984 0.9965668454044068 1.0 1.0 3 Q16543,P62993 2 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..067a5457830883d3ddd5394e40fed29b7be228a5 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "Butyrophilin btn family interactions", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd22 mediated bcr regulation", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Chylomicron remodeling", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen degradation", "Collagen formation", "Common pathway of fibrin clot formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of particulate exogenous antigens phagosomes", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Dectin 2 family", "Defective cftr causes cystic fibrosis", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 activates ptk6 signaling", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythropoietin activates phosphoinositide 3 kinase pi3k", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Erythropoietin activates stat5", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna editing c to u conversion", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 promotes hif1a stabilization", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Reelin signalling pathway", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of fzd by ubiquitination", "Regulation of gene expression in beta cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of signaling by nodal", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 and foxp3 control the development of regulatory t lymphocytes tregs", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in bcr signaling", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of keratinocytes", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx1 regulates transcription of genes involved in interleukin signaling", "Runx1 regulates transcription of genes involved in wnt signaling", "Runx2 regulates bone development", "Runx2 regulates chondrocyte maturation", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates immune response and cell migration", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scavenging of heme from plasma", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sodium proton exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 dependent activation of irf3 irf7", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldl clearance", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "APLP2", "APOB", "APOBEC3C", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCL10", "BCS1L", "BDH2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRD8", "BSG", "BTN2A1", "BUB1B", "BUB3", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASP2", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX4", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD46", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDS2", "CENPI", "CENPM", "CEP290", "CERK", "CERS1", "CERS2", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHTOP", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLINT1", "CLIP1", "CLNS1A", "CLTA", "CLTB", "CLTC", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT4", "CNOT9", "COG7", "COLEC12", "COLGALT1", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7C", "CPD", "CPE", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT2", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTC", "CWC15", "CXADR", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCD", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DPH2", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DSC1", "DSC2", "DSC3", "DSG2", "DSP", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFTUD2", "EGFR", "EHD1", "EHMT1", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERLIN2", "ERO1A", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120B", "FAM3C", "FAM49B", "FAM91A1", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNTB", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF3C1", "GTF3C3", "GTF3C4", "GUSB", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILK", "IMMT", "IMPAD1", "IMPDH1", "IMPDH2", "INCENP", "INTS10", "INTS12", "INTS13", "INTS14", "INTS2", "INTS3", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISCU", "IST1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0391", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KIRREL1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "LAMB1", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LRP1", "LRP2", "LRPPRC", "LRRC1", "LRRC8E", "LSM2", "LSM3", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LYN", "LYPLA1", "LZTFL1", "M6PR", "MAD2L1", "MAGED2", "MAGT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MAP2K1", "MAP2K4", "MAPK1", "MAPK3", "MAPRE1", "MARC1", "MARCKS", "MARS", "MASTL", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED12", "MED16", "MED17", "MED24", "MED4", "METAP2", "METTL1", "METTL7A", "MFGE8", "MFN1", "MGAT1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPRIP", "MPST", "MPV17", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL58", "MRPL9", "MRPS15", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVB12A", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1C", "MYO6", "MYO9B", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NBR1", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCK1", "NCKAP1", "NCL", "NCSTN", "ND1", "ND5", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEK9", "NELFCD", "NELFE", "NEU1", "NF1", "NFS1", "NHLRC2", "NHP2", "NID1", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NT5C2", "NT5C3B", "NTHL1", "NUB1", "NUBP2", "NUCB1", "NUDC", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD7B", "OXA1L", "P3H1", "P3H3", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PANK4", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KB", "PICALM", "PIGA", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIN1", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "POFUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RALB", "RALGAPB", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "REL", "REPS1", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT1", "RHOT2", "RIF1", "RINT1", "RIOX2", "RIPK1", "RNASET2", "RNF14", "RNF2", "RNF220", "RNF40", "RNMT", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAGC", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP8", "RRP9", "RSF1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERINC1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD2", "SMYD3", "SNAP23", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SORL1", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX18", "STX3", "STX5", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF1", "SURF4", "SUZ12", "SV2A", "SYMPK", "SYNE2", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARS", "TARS2", "TAX1BP1", "TBC1D10B", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL3", "TCEA1", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFG", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM30A", "TMEM59", "TMEM87A", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNKS1BP1", "TNPO1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM3", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRMT10C", "TRMT11", "TRRAP", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSR1", "TST", "TSTA3", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TULP3", "TWF1", "TWISTNB", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBR4", "UBTF", "UBXN1", "UCHL5", "UCK2", "UFD1", "UFL1", "UGCG", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VLDLR", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WBP11", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR4", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WIPI2", "XAB2", "XPC", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZFYVE16", "ZMYM2", "ZNF512B", "ZNF638", "ZW10"], "leading_proteins": ["AAMP", "ACBD5", "ACOX1", "ACP6", "ACSL4", "ADGRE5", "ADPGK", "AGK", "AGPAT1", "AGPS", "AKT1", "AKT1S1", "AKT2", "ALDH3A2", "ALG1", "ALG11", "ALG12", "ALKBH5", "ANAPC16", "ANAPC5", "ANAPC7", "ANKLE2", "ANO6", "AP2M1", "AP3S1", "APLP2", "APOB", "APOO", "APOOL", "APP", "ARF4", "ARL1", "ARL6IP5", "ARPC5", "ARV1", "ASAH1", "ASCC2", "ATG4B", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5J2", "ATP5L", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1E1", "ATP7A", "B4GAT1", "BAIAP2", "BSG", "C19orf70", "C1QBP", "CALU", "CAMK2G", "CANT1", "CANX", "CCNA2", "CCNB1", "CCNB2", "CD47", "CDC20", "CDC27", "CDC37", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CERK", "CERS1", "CERS2", "CETN2", "CHKA", "CHMP2A", "CHMP3", "CHUK", "CKAP4", "CLCN3", "CLCN7", "COLEC12", "COMT", "COPB2", "COPG1", "COPS3", "COPS4", "COPS8", "COX15", "COX2", "COX4I1", "CPD", "CPE", "CPT2", "CREG1", "CSNK1A1", "CTNNB1", "CTNND1", "CTSA", "CTSB", "CTSC", "CUL1", "CYP51A1", "DCTN2", "DCTN3", "DDRGK1", "DERL1", "DHCR24", "DHFR", "DHRS7B", "DLD", "DLG3", "DNAJC11", "DNASE2", "DNM2", "DSG2", "ECE1", "EGFR", "EHD1", "EHMT1", "EHMT2", "EIF2S1", "EIF2S2", "ELMO2", "EMD", "ENDOD1", "EPHA7", "ERAP1", "EXOC7", "F11R", "FAM3C", "FAM49B", "FAR1", "FDPS", "FKBP1A", "FKBP9", "FLOT1", "FLOT2", "FNTB", "FTO", "FUCA1", "FUCA2", "GAA", "GALNT1", "GALNT2", "GBA", "GDAP1", "GGCX", "GGH", "GLA", "GLB1", "GLG1", "GM2A", "GMPPB", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNS", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOSR1", "GPD2", "GRB2", "GSK3A", "GUSB", "HACD3", "HAUS5", "HDAC1", "HEXA", "HEXB", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HMOX2", "HPSE", "HS2ST1", "HSD17B12", "HSP90B1", "ICMT", "IFNGR1", "IGF2R", "IKBKB", "IMMT", "IRS4", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "KDELR1", "KDELR3", "KDM1B", "KDSR", "KEAP1", "KHDRBS1", "KIF18B", "KIRREL1", "KPNA2", "LAMB1", "LAMP1", "LAMTOR1", "LBR", "LDLR", "LETM1", "LGALS3BP", "LGMN", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LPCAT1", "LRP1", "LRP2", "LTA4H", "LYN", "M6PR", "MAGT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MAVS", "MBOAT7", "MCAM", "MED17", "METTL7A", "MFGE8", "MFN1", "MGAT1", "MGST2", "MICU1", "MICU2", "MMGT1", "MORC2", "MOV10", "MPP2", "MPV17", "MRC2", "MSMO1", "MTCH1", "MTOR", "MTX1", "NAGLU", "NAMPT", "NAPA", "NBR1", "NCK1", "NCSTN", "ND1", "ND5", "NDC1", "NDUFA11", "NDUFA13", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB8", "NDUFB9", "NECTIN2", "NEDD4L", "NEFL", "NEU1", "NID1", "NPC1", "NPC2", "NRP1", "NUCB1", "NUP205", "NUP37", "NUP93", "OCLN", "OCRL", "OTUD7B", "P4HB", "PCM1", "PDCD6IP", "PEX14", "PEX19", "PGRMC1", "PGRMC2", "PI4K2A", "PI4KB", "PIGK", "PIGU", "PISD", "PITPNB", "PKN2", "PLA2G15", "PLD3", "PLK1", "PMPCA", "PON2", "POR", "PPME1", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP6C", "PPT1", "PPT2", "PRCP", "PREB", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCSH", "PRMT5", "PROCR", "PSAP", "PSMA6", "PSMB2", "PSME3", "PTDSS1", "PTK2", "PTPRF", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABEPK", "RABGGTB", "RAC1", "RACGAP1", "RAD23B", "RALA", "RAP1GDS1", "RDH11", "RDH13", "RETSAT", "RINT1", "RIPK1", "RNASET2", "RPN1", "RRAGC", "RTN3", "RTN4", "SACM1L", "SAMM50", "SAR1B", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SDCBP", "SEC11A", "SEC22B", "SEL1L", "SGPL1", "SIGMAR1", "SKP1", "SLC12A2", "SLC1A5", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC29A1", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SMYD2", "SNW1", "SOAT1", "SORL1", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPPL2A", "SPTLC1", "SQLE", "SQSTM1", "SRPK1", "SRPK2", "SRPRB", "SSR1", "STARD3", "STARD3NL", "STARD7", "STT3A", "STUB1", "STX10", "STX18", "STX5", "SULT2A1", "SURF1", "SURF4", "TAB1", "TAP1", "TAX1BP1", "TBC1D15", "TBL1XR1", "TECR", "TEX264", "TFRC", "TGOLN2", "TIMM17A", "TIMM17B", "TIMM23", "TMED10", "TMED2", "TMED7", "TMEM30A", "TMEM59", "TMEM87A", "TMOD1", "TMPO", "TMX3", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOR1B", "TP53", "TPP1", "TRIM25", "TSC2", "TTC26", "TTYH3", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UGCG", "UNC119B", 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syndrome 0.7359136683713818 2.2927086563352597 0.0218647838458403 0.9999984116992904 0.6916285996335741 10 Q9Y624,Q96J84,Q16625 3 +Mitochondrial complex iv assembly 0.6839113030010858 2.211205061466438 0.0270216400512941 0.9999999347889108 0.6916285996335741 13 P14406,Q7KZN9,Q15526,Q9Y2R0,P13073 5 +Metabolism of spingolipids in er and golgi apparatus 0.8513779527558962 2.056782572530976 0.0397071451874799 0.9999999999764584 0.6916285996335741 5 O95470,Q10472,Q8TCT0,Q16739 4 +Calcium regulation in cardiac cells 0.5594672463939526 1.9909049958768896 0.0464913328711149 0.9999999999996748 0.6916285996335741 21 P10644,P54709,P17612,P62942,P16615,P04899,P0DP25,P20020 8 +Statin inhibition of cholesterol production 0.7529432768663223 1.97157685524165 0.0486579314789483 0.9999999999999176 0.6916285996335741 7 Q8WTV0,Q07954,P04114,P01130,Q14534 5 +Familial hyperlipidemia type 3 0.88356838307641 1.9486147253832744 0.0513414522632305 0.999999999999985 0.6916285996335741 4 Q07954,P98155,P01130 3 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O14949,O95169,P14406,O96000,Q9Y6M9,P00403,Q9P0J0,Q86Y39,Q9UDW1,O43676,P31751,Q96J02,O75438,P13073 14 +Alzheimers disease 0.3835858807736104 1.6566014271427512 0.0976000836388382 1.0 0.6916285996335741 81 P12235,P49721,P12236,P45880,O95197,P16615,Q92542,P60900,Q07954,P21796,Q9Y277,Q9NQC3,P05067,P31751 14 +Ebola virus infection in host 0.4966134963692284 1.6523165858379032 0.0984700299248744 1.0 0.6916285996335741 45 P20339,O75569,P61916,O15118,P10321,P06756,P01889,P04439,P05556,Q07021,P00533,Q08431,P51149,P07858,P51151 15 +Oxidation by cytochrome p450 0.8091177435224507 1.6435493097303682 0.1002693319178882 1.0 0.6916285996335741 4 P16435,O43169,Q16850 3 +Copper homeostasis 0.6599297436731786 1.6405784883398211 0.1008849434303271 1.0 0.6916285996335741 8 P05067 1 +Endothelin pathways 0.656411329159041 1.6227570606422237 0.1046413481888117 1.0 0.6916285996335741 8 P16615,P42892 2 +Insulin signaling in adipocytes diabetic condition 0.7492928052531338 1.6127360987528714 0.1068018542966657 1.0 0.6916285996335741 5 P14672,P31751 2 +Insulin signaling in adipocytes normal condition 0.7492928052531338 1.6127360987528714 0.1068018542966657 1.0 0.6916285996335741 5 P14672,P31751 2 +Neural crest cell migration in cancer 0.6517443829891443 1.5990730993446156 0.1098043611090613 1.0 0.6916285996335741 8 Q99523 1 +S1p receptor signal transduction 0.6252986821495262 1.5841095954509734 0.1131687811730453 1.0 0.6916285996335741 9 Q9H0H5,P04899,Q13510,P31751 4 +Familial hyperlipidemia type 4 0.7898329665405838 1.5633758281032788 0.117964222193414 1.0 0.7097470748214686 4 Q07954 1 +Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.6432248177332794 1.555708005918485 0.1197775419701223 1.0 0.7097470748214686 8 P20339,P51148,P61020,P31943 4 +P53 transcriptional gene network 0.642119144404633 1.550067999929637 0.1211251956570207 1.0 0.7097470748214686 8 P04066 1 +Complement system 0.5659314890753475 1.5307217734671954 0.1258381701586266 1.0 0.7097470748214686 13 P98164,P17612,Q07021,P08754,P15529,P04899,P07942 7 +Vitamin b12 metabolism 0.6130989027182362 1.5194538375559516 0.1286482992342308 1.0 0.7097470748214686 9 P04114,P01130,P98164 3 +Allograft rejection 0.5874623004181045 1.5043361654764025 0.1324948315288572 1.0 0.7097470748214686 10 P04439,P10321 2 +Lipid particles composition 0.938708620124549 1.4981185116764326 0.1341024623229889 1.0 0.7097470748214686 2 P04114 1 +Regulatory circuits of the stat3 signaling pathway 0.5851465852376309 1.4915100646507342 0.1358276307743833 1.0 0.7097470748214686 10 P15260,P42345,P00533 3 +Camkk2 pathway 0.5848159408305514 1.4896775478452744 0.1363090408597522 1.0 0.7097470748214686 10 P42345,O76024,Q13501,P09601 4 +Transcription factors regulate mirnas related to cardiac hypertrophy 0.759425786471756 1.4362101105385046 0.1509425629142229 1.0 0.7397442663362056 4 P31751 1 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.5397771116460306 1.4321194607798964 0.1521096358975431 1.0 0.7397442663362056 14 O60725,P42167,P55209,O75844 4 +Familial hyperlipidemia type 2 0.8580288061333038 1.4188394548177132 0.1559458270282609 1.0 0.7397442663362056 3 P04114 1 +Ccl18 signaling pathway 0.5704241158759769 1.4096393943181116 0.1586461885456527 1.0 0.7397442663362056 10 Q86UE4,P11166,P19022,P00403 4 +Small cell lung cancer 0.5257986290956892 1.4093117213315165 0.1587430144046187 1.0 0.7397442663362056 15 P07942,P06756,P31751 3 +Metabolic pathway of ldl hdl and tg including diseases 0.7394609198560657 1.3523280642963025 0.1762703904226916 1.0 0.7430209417992328 4 P04114,P01130 2 +Immune response to tuberculosis 0.8401551283680877 1.3475341404289558 0.1778082655855253 1.0 0.7430209417992328 3 P15260 1 +Head and neck squamous cell carcinoma 0.5134489341173961 1.3300495135735733 0.1835019581336749 1.0 0.7430209417992328 15 P62942,P42345,P00533,P08069,P49815,P31751 6 +Familial hyperlipidemia type 1 0.8350904281212077 1.3273288336239877 0.1843999298153491 1.0 0.7430209417992328 3 Q07954 1 +Familial hyperlipidemia type 5 0.8350904281212077 1.3273288336239877 0.1843999298153491 1.0 0.7430209417992328 3 Q07954 1 +Relationship between inflammation cox2 and egfr 0.6385190287778142 1.3269504674669617 0.184525068327624 1.0 0.7430209417992328 6 P31751 1 +Ranklrank signaling pathway 0.4994101881029774 1.3072461676013545 0.1911291204825276 1.0 0.7437856270126948 16 Q13501 1 +Cholesterol biosynthesis with skeletal dysplasias 0.6795623532404351 1.3004024335365096 0.1934630763112617 1.0 0.7437856270126948 5 Q15392,Q14739,Q16850 3 +Glycerolipids and glycerophospholipids 0.6776826983658406 1.2919166802234037 0.1963860005468354 1.0 0.7437856270126948 5 Q9UG56,P48651,O14735 3 +Type ii diabetes mellitus 0.6298203736793333 1.2848060451820502 0.1988600693733997 1.0 0.7437856270126948 6 P14672,Q15526 2 +Adipogenesis 0.5045191179785312 1.272466845736696 0.2032072966619686 1.0 0.7437856270126948 15 Q9NZ45,O75844,P43490 3 +Autosomal recessive osteopetrosis pathways 0.8209917851830573 1.271106049485221 0.2036909234921256 1.0 0.7437856270126948 3 P51798 1 +Familial partial lipodystrophy fpld 0.6073300406491229 1.2611220613437042 0.2072648733080109 1.0 0.7437856270126948 7 O75844,P31751 2 +Mitochondrial complex iii assembly 0.5850144703106582 1.2554528406288192 0.2093144175389416 1.0 0.7437856270126948 8 O14949,Q6DKK2,Q9UDW1 3 +Extracellular vesiclemediated signaling in recipient cells 0.6035507175631032 1.2421753192066889 0.2141718837247002 1.0 0.7437856270126948 7 Q08431,P00533 2 +Network map of sarscov2 signaling pathway 0.4583362302617132 1.2385807448838029 0.2155008025285125 1.0 0.7437856270126948 26 Q08380,O95067,Q07021,P42345,Q96B36,Q96J02,P07858,Q7Z434 8 +Orexin receptor pathway 0.4859941894642937 1.2177381948484158 0.2233234776172958 1.0 0.7577942723643073 16 P11166,P01130,P14672 3 +Monoamine transport 0.8049180327868792 1.2070922262794723 0.2273966283166006 1.0 0.7630420194623712 3 Q92692,O15127 2 +Zinc homeostasis 0.8666011143887418 1.2004142039708166 0.2299785151499094 1.0 0.7674421168538414 2 Q8NEW0 1 +Vitamin d metabolism 0.8006894330937309 1.1902751825189506 0.2339382517429451 1.0 0.772124065861961 3 P38435 1 +Amyotrophic lateral sclerosis als 0.5289384498535694 1.176297985518618 0.2394758204934088 1.0 0.7796091473946298 10 P07196,P20339,Q9BUN8 3 +Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.6973208791845166 1.174791070189934 0.2400783136016575 1.0 0.7796091473946298 4 P09601 1 +Nrp1triggered signaling pathways in pancreatic cancer 0.4959642296740347 1.1579859569973974 0.2468697672364028 1.0 0.7875121052336689 14 P31751,P00533 2 +Myometrial relaxation and contraction pathways 0.4756285753644302 1.1482853019100034 0.2508508047543074 1.0 0.787815837654049 16 P10644,P16615,P0DP25 3 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.7872131147541015 1.1367699650013787 0.2556344622912943 1.0 0.7882397146984421 3 P08195,Q15758 2 +Inclusion body myositis 0.7851465342198681 1.1285791732389714 0.259075400488745 1.0 0.7903108176525352 3 P05067 1 +Hippomerlin signaling dysregulation 0.4350402297538417 1.0804863097418058 0.2799256799146103 1.0 0.812341361573203 21 P10644,P06756,P19022,P17612,P05556,P00533,P08069 7 +Wnt signaling pathway 0.4969924873227971 1.0672949403098135 0.2858386721634638 1.0 0.8146163662634162 12 Q9BTU6,P49815,P42345 3 +Nephrotic syndrome 0.4815769540533402 1.0671038361829996 0.2859249497480864 1.0 0.8146163662634162 14 O75844,Q14108,O00592 3 +Omega3 omega6 fatty acid synthesis 0.6272965879265022 1.0640167130697709 0.2873211284102055 1.0 0.8147509932383292 5 Q15067,O95864,O95573,O60488 4 +Vitamin a and carotenoid metabolism 0.7609574177186791 1.0330777274560137 0.3015675254466354 1.0 0.8393861076947825 3 Q8WTV0 1 +Apoptosisrelated network due to altered notch3 in ovarian cancer 0.4556307869512864 1.0137750687805855 0.3106900942233181 1.0 0.8432257133518335 16 Q13501 1 +Dopamine metabolism 0.8203867584398705 1.0127966563513948 0.311157298140877 1.0 0.8432257133518335 2 P21964 1 +Embryonic stem cell pluripotency pathways 0.483413889967942 0.9860121632536571 0.3241271441882483 1.0 0.8521261494820475 12 P31751,P00533 2 +7oxoc and 7betahc pathways 0.5309054057927108 0.9723822212769294 0.3308604332896636 1.0 0.8613780245989519 8 O15118 1 +Spinal cord injury 0.4207072167160914 0.9660009530929556 0.3340437041181634 1.0 0.8622324670400457 22 O94813,Q08722,Q9NQC3 3 +Hedgehog signaling pathway wp4249 0.6445023201972949 0.9530922895584072 0.3405433124307218 1.0 0.8684453744543471 4 P98164,P17612 2 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.7377049180327601 0.942138889644895 0.3461215361003895 1.0 0.8684453744543471 3 Q14145,P09601 2 +Influence of laminopathies on wnt signaling 0.4855246799328952 0.9295403282361092 0.3526091355163947 1.0 0.8701916451364852 10 O60725,O75844,P14672 3 +Metapathway biotransformation phase i and ii 0.4149918931635254 0.9288340644136708 0.3529750878450974 1.0 0.8701916451364852 21 P21964,Q16850,O15217,Q7LGA3,Q86UY6 5 +Endometrial cancer 0.4635856002098338 0.90702534973203 0.364393392055087 1.0 0.8910672421104153 13 P31751 1 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.5158133572125382 0.8933749025246317 0.3716564382359735 1.0 0.9051632608650324 8 P08069,P05556,P42345 3 +Oxidative phosphorylation 0.4146356933114568 0.8884871296880261 0.3742787758823831 1.0 0.9078890788472266 30 O75787,O75964,O96000,Q9Y6M9,Q15904,Q86Y39,P03886,O75438,P03915 9 +Hair follicle development cytodifferentiation part 3 of 3 0.6277043371624207 0.8833133185550849 0.3770670097800228 1.0 0.9097792906823498 4 Q02487,P00533 2 +Vasopressinregulated water reabsorption 0.451352975402945 0.8756999956087071 0.3811931477460342 1.0 0.9097792906823498 14 P20339,P51148,P61020,Q13561 4 +Purinergic signaling 0.719016393442611 0.869900451697827 0.3843548086015129 1.0 0.9097792906823498 3 P04899,P08754 2 +Nucleotidebinding oligomerization domain nod pathway 0.5109779133660078 0.8681057176141896 0.3853364613027308 1.0 0.9097792906823498 8 Q13685 1 +Cannabinoid receptor signaling 0.6207393925503735 0.8545503608352751 0.3928001180822651 1.0 0.9118595569725294 4 P10644 1 +Type ii interferon signaling ifng 0.5077829158807411 0.8514261716591275 0.3945326585871989 1.0 0.9118595569725294 8 Q03518,P15260 2 +Nanomaterial induced apoptosis 0.5354195283284036 0.825761183199195 0.4089395774947046 1.0 0.9199072000468294 6 O95831 1 +Angiopoietinlike protein 8 regulatory pathway 0.4003112148078476 0.7802450233622523 0.4352466657380205 1.0 0.9228956332562892 28 O75955,P42345,P14672,Q14254,P11166,P49815,O14654,P31751 8 +Neuroinflammation 0.6889889702736267 0.7559870286995404 0.4496569728149744 1.0 0.936526936483602 3 P00403 1 +Target of rapamycin tor signaling 0.4508702388887594 0.7329660626285499 0.4635791285605084 1.0 0.9409149444260896 10 P62942,Q9HB90,P49815,P42345 4 +Splicing factor nova regulated synaptic proteins 0.4206864855705903 0.7268377303707421 0.4673253667143879 1.0 0.9409149444260896 15 Q9UNS2,P19022,Q06481 3 +Vitamin d receptor pathway 0.4273717256649001 0.7243844513195657 0.4688297429019892 1.0 0.9409149444260896 14 P14672,Q96KA5,P48960 3 +Insulin signaling 0.3903922228744368 0.7001605715624324 0.4838270318780928 1.0 0.9409149444260896 41 P10586,Q9H4M9,O75955,P42345,P14672,Q14254,P08069,P11166,O14654,P31751 10 +Follicle stimulating hormone fsh signaling pathway 0.4948866998953752 0.6973932281010153 0.485556738354038 1.0 0.9409149444260896 7 P17612,P42345 2 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.6670047736970617 0.6747744643745531 0.499819066384298 1.0 0.9499100632703243 3 P42345 1 +Gastric cancer network 2 0.41255714903757 0.6743037630662891 0.5001182121191443 1.0 0.9499100632703243 15 Q86UE4,P00533 2 +Primary focal segmental glomerulosclerosis fsgs 0.3811708965031605 0.6659832841332403 0.5054217849068812 1.0 0.9515767981985478 22 O00592,P06756,P19022,Q14108 4 +Physiological and pathological hypertrophy of the heart 0.5008204791598372 0.6603777479614789 0.5090114482685744 1.0 0.9515767981985478 6 P63000,P61586,P40763,Q9P2K5,Q08209 5 +Arrhythmogenic right ventricular cardiomyopathy 0.4163988901350233 0.6556894793212164 0.5120239394280266 1.0 0.9515767981985478 14 P06756,P19022,P16615,P05556,Q14126,P50402 6 +Striated muscle contraction pathway 0.5687590181174207 0.644592859437771 0.5191910634556742 1.0 0.9591901713875792 4 P28289,P08670 2 +Thyroid hormones production and peripheral downstream signaling effects 0.4029823151051108 0.6128032625980033 0.540006433335245 1.0 0.9745816132184064 15 P06756,P49815,P17612,P42345 4 +Micrornas in cardiomyocyte hypertrophy 0.3701353164162613 0.5997689258831905 0.5486602453364609 1.0 0.9745816132184064 20 P08069,Q9P2K5,P42345,P31751 4 +Mitochondrial complex i assembly model oxphos system 0.3744673816208842 0.5948121636939542 0.5519690359019647 1.0 0.9745816132184064 25 O96000,Q9Y6M9,Q9P0J0,O43676,P03886,O75438,O95169,P03915 8 +Leukocyteintrinsic hippo pathway functions 0.5173884514435773 0.578216298729118 0.5631180961677269 1.0 0.9745816132184064 5 P63000,P51153,Q13043,P27348 4 +Synaptic vesicle pathway 0.4020280844731249 0.5665865162205455 0.5709951380529663 1.0 0.9745816132184064 14 Q13277,P12235,Q96CW1,O00429 4 +Nrf2 pathway 0.3649342232392136 0.5445324505934248 0.5860751240466306 1.0 0.9778712014479696 22 Q13501,P09601,P14672,P11166,O15217,Q15043 6 +Vitamin dsensitive calcium signaling in depression 0.505365859833272 0.5278895834807134 0.5975759749041305 1.0 0.9795110961471052 5 P20020 1 +Ectoderm differentiation 0.3559297274620254 0.5049660326626888 0.6135826936086022 1.0 0.9795110961471052 19 P16278,O00592 2 +Sarscov2 and covid19 pathway 0.5310146585137632 0.5000457886811278 0.6170428366070861 1.0 0.9795110961471052 4 O14786,Q8WTV0 2 +Estrogen signaling pathway 0.4627502461437448 0.484442294558248 0.6280720082938851 1.0 0.9795110961471052 6 P17612,Q02750,P31749,P28482,O14920 5 +Malignant pleural mesothelioma 0.3321004077669397 0.469526947671158 0.638693027670822 1.0 0.9795110961471052 67 P06756,P19022,P08195,P05556,Q08722,Q07820,P42345,P00533,P08069,Q02487,O00592,P11166,P31751,P07942,Q14574 15 +Regulation of apoptosis by parathyroid hormonerelated protein 0.4589665209846126 0.46746324454812 0.6401684830633649 1.0 0.9795110961471052 6 Q9BXK5 1 +Omega9 fatty acid synthesis 0.4509353462422059 0.4318018136138448 0.6658854612826275 1.0 0.9795110961471052 6 O95573,O00767,O95864,P33121,O60488 5 +Nanoparticlemediated activation of receptor signaling 0.4248824452452148 0.4309071454308271 0.6665358877042165 1.0 0.9795110961471052 8 P00533 1 +Dna damage response only atm dependent 0.3609683825609417 0.4303026208213859 0.6669755208993886 1.0 0.9795110961471052 17 P01130 1 +Eicosanoid synthesis 0.6601114388725193 0.428923461857923 0.6679789254484452 1.0 0.9795110961471052 2 P09960 1 +Tyrobp causal network in microglia 0.5104248906744155 0.4253082502419359 0.6706119800484138 1.0 0.9795110961471052 4 P61916 1 +Folate metabolism 0.3715481087438639 0.4153665728829376 0.6778735731614072 1.0 0.9795110961471052 15 P04114,P01130,Q8WTV0 3 +Hepatitis b infection 0.3500264749426656 0.4114750317485565 0.6807242458627387 1.0 0.979885561722635 25 Q15904,Q9Y277 2 +Nonsmall cell lung cancer 0.3747695787565608 0.4017482203601388 0.6878693328292029 1.0 0.979885561722635 14 P31751 1 +Drug induction of bile acid pathway 0.6506063585709783 0.4001402204063146 0.6890532416985582 1.0 0.979885561722635 2 Q06520 1 +Nuclear receptors in lipid metabolism and toxicity 0.6506063585709538 0.4001402204062425 0.6890532416986113 1.0 0.979885561722635 2 P28288 1 +Tgfbeta signaling pathway 0.3526001031469378 0.3886091568297575 0.6975652920302775 1.0 0.9890362356485624 33 Q96J02,P05556,P05067,Q96PU5 4 +Complement and coagulation cascades 0.5766120770818973 0.3713916788335088 0.7103458224366339 1.0 0.992054765907683 3 P15529 1 +H19 action rbe2f1 signaling and cdkbetacatenin activity 0.4359234183571067 0.3666808041340195 0.7138571267818459 1.0 0.992054765907683 6 Q16527 1 +Notch signaling pathway 0.3799045277419427 0.3608554738836996 0.7182074906272369 1.0 0.992054765907683 11 Q92542 1 +Arachidonate epoxygenase epoxide hydrolase 0.6368403802032219 0.3601220350532738 0.7187558751675762 1.0 0.992054765907683 2 P34913 1 +Glycosylation and related congenital defects 0.3818707753348827 0.3562914876598813 0.721622283483047 1.0 0.9928470597352174 10 Q9BV10,Q9BT22,Q9Y5P6,Q2TAA5,Q9H0U3 5 +Neuroinflammation and glutamatergic signaling 0.3369726102519064 0.3244471348885355 0.7455995395115056 1.0 1.0 24 P09622,P15260,P11166 3 +T cell receptor and costimulatory signaling 0.4804854050508339 0.3233576313339398 0.7464244126831407 1.0 1.0 4 P49840,Q08209,P48729 3 +Progeriaassociated lipodystrophy 0.3857386617413525 0.3085895559697726 0.7576337665040913 1.0 1.0 9 O75844 1 +Triacylglyceride synthesis 0.5544262295081933 0.3073925559349643 0.7585445935994215 1.0 1.0 3 O00116,Q99943 2 +Hair follicle development organogenesis part 2 of 3 0.5499303727562399 0.2950535298314504 0.7679529879973175 1.0 1.0 3 P05556 1 +Focal adhesion pi3kaktmtorsignaling pathway 0.3402265320533773 0.2783080809453814 0.7807758733778933 1.0 1.0 41 P06756,P05556,P14672,P42345,P08069,P00533,P11166,P61019,O14654,P07942,P31751 11 +Caloric restriction and aging 0.4402050504237926 0.2756438521609506 0.7828216247892004 1.0 1.0 5 P43490 1 +Selenium micronutrient network 0.3604127596214891 0.2744908835278578 0.7837074085717128 1.0 1.0 12 P04114,P01130 2 +G protein signaling pathways 0.346489942589683 0.2658576609305184 0.7903488336004645 1.0 1.0 15 P10644,P04899,P17612,P08754 4 +Pi3kakt signaling pathway 0.338646738182492 0.265666583053352 0.7904960016270492 1.0 1.0 40 P06756,P05556,Q07820,P42345,P00533,P08069,P07942,P31751 8 +Sulfation biotransformation reaction 0.4621187274516081 0.2655092591998454 0.790617177939952 1.0 1.0 4 Q06520,P00390,P11413 3 +Ras signaling 0.3356515051886627 0.2635974037033215 0.7920901593364986 1.0 1.0 32 P20339,P17612,P61020,P00533,P0DP25,P51148,P11233,P31751 8 +Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition 0.4220266811588908 0.21360837043069 0.8308524713969312 1.0 1.0 5 P19022 1 +Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.3920572609366161 0.1911391877703267 0.8484165461835507 1.0 1.0 6 P18031,P00533 2 +Phase i biotransformations non p450 0.5039836342390711 0.1824655555033809 0.855217383291438 1.0 1.0 3 P38571 1 +Autophagy 0.3883426927235624 0.1775045647369254 0.8591120800266032 1.0 1.0 6 P42345,Q9Y4P8 2 +Map3k1 role in promoting and blocking gonadal determination 0.5003278688524566 0.1746295349442683 0.861370739643488 1.0 1.0 3 P35222,P61586 2 +Glycogen synthesis and degradation 0.3232527708745475 0.1616602736206255 0.8715733900133025 1.0 1.0 16 P52789,P0DP25 2 +Cardiac hypertrophic response 0.3338630177754303 0.1407788615571635 0.8880446427719018 1.0 1.0 12 P31751 1 +Mirna regulation of prostate cancer signaling pathways 0.3686802363755685 0.1355441959384514 0.8921816233447202 1.0 1.0 7 P35222,Q02750,P42345,Q8NCF5,P28482,P62993 6 +Angiogenesis 0.4803278688524663 0.1348437103130983 0.8927354455852654 1.0 1.0 3 Q05397,P28482 2 +Initiation of transcription and translation elongation at the hiv1 ltr 0.3683519369665131 0.1343411460484151 0.8931328182719942 1.0 1.0 7 Q92769,Q08209,P50750,Q13547,P18615,Q8IXH7 6 +Thyroid stimulating hormone tsh signaling pathway 0.3060955518945714 0.1248276633623664 0.9006599864806861 1.0 1.0 18 P62753,P11802,Q14344,P27695,P40763,Q14160,Q15418,Q02750,P42345,P08754,P08069,P42224,P04899,P31749,P28482,P24941,P63096 17 +Hippoyap signaling pathway 0.5260570304817999 0.122035489177529 0.9028709120124736 1.0 1.0 2 Q13043 1 +Bdnftrkb signaling 0.3537116560683669 0.1183131700746827 0.9058195224829004 1.0 1.0 8 P42345 1 +Wnt signaling in kidney disease 0.5168797115699667 0.1094538115893897 0.912842554604662 1.0 1.0 2 P35222 1 +Serotonin htr1 group and fos pathway 0.3603403680253864 0.1055933482257589 0.91590500259235 1.0 1.0 7 P04899,P08754 2 +Mapk and nfkb signaling pathways inhibited by yersinia yopj 0.4622950819672204 0.1034979773258335 0.917567754735088 1.0 1.0 3 O14920,P28482 2 +Vitamin d in inflammatory diseases 0.4622950819672203 0.1034979773258332 0.9175677547350882 1.0 1.0 3 O14920,Q08209 2 +Thymic stromal lymphopoietin tslp signaling pathway 0.3271550220465017 0.1007036580582285 0.9197857074285424 1.0 1.0 11 Q9BTU6 1 +Neural crest differentiation 0.3634301704396601 0.0920639772790255 0.926647208831596 1.0 1.0 6 P19022 1 +Somatroph axis gh and its relationship to dietary restriction and aging 0.3875910970595399 0.0770164072738196 0.9386104926180108 1.0 1.0 4 P42345 1 +Regucalcin in proximal tubule epithelial kidney cells 0.3516086671043944 0.0756499017497625 0.9396976343236628 1.0 1.0 7 P42574,Q13283,P42345,Q8NE86,P31749,P28482 6 +Praderwilli and angelman syndrome 0.3684383202099724 0.0598425330392189 0.952281049791166 1.0 1.0 5 P11802,Q15154,Q7L576,O95714 4 +Pregnane x receptor pathway 0.366797900262464 0.05590463609752 0.9554177775363206 1.0 1.0 5 Q06520,P08183,P62195,Q99615 4 +Nodlike receptor nlr signaling pathway 0.4621435594886796 0.0551254541135315 0.95603851752279 1.0 1.0 2 O14920 1 +Altered glycosylation of muc1 in tumor microenvironment 0.4621435594886796 0.0551254541135315 0.95603851752279 1.0 1.0 2 O14920 1 +Ovarian infertility 0.4575549000327634 0.0520109626759746 0.9585199582859096 1.0 1.0 2 P11802 1 +Liver x receptor pathway 0.4503441494591832 0.0475044159180791 0.9621112109173172 1.0 1.0 2 O00767 1 +Nocgmppkg mediated neuroprotection 0.3664252200282965 0.0388114703040504 0.969040699745692 1.0 1.0 4 P07196,Q13555 2 +Benzoapyrene metabolism 0.333988856112743 0.0181993136692253 0.9854798501591562 1.0 1.0 2 P07099 1 +Hostpathogen interaction of human coronaviruses apoptosis 0.3512627090849463 0.0157501522713423 0.9874337162218904 1.0 1.0 4 Q07820,P31749,P42574 3 +Brainderived neurotrophic factor bdnf signaling pathway 0.3058204790543557 0.0120489925198822 0.9903865275068582 1.0 1.0 42 Q13501,Q99523,Q96P70 3 +Srebf and mir33 in cholesterol and lipid homeostasis 0.3318439627028109 0.0006495234232512 0.9994817553251476 1.0 1.0 6 P01130 1 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..390012a962a2d5f842467961b9a0eba8563bc3d3 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes associated with the development of rheumatoid arthritis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpcrs class b secretinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanomaterialinduced inflammasome activation", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoblast signaling", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 altering angiogenesis via nrp1", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Scfa and skeletal muscle substrate metabolism", "Selective expression of chemokine receptors during tcell polarization", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Tamoxifen metabolism", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCD3", "ABCF1", "ABCF2", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ACVR1B", "ADAR", "ADGRE5", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "AMOT", "ANAPC1", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APC", "APEX1", "APLP2", "APMAP", "APOB", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL8B", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ATG3", "ATG7", "ATIC", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AURKA", "B3GALT6", "BAG3", "BAG4", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAT1", "BCAT2", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BLVRA", "BLVRB", "BRCA1", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "C1QBP", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZB", "CARM1", "CASP2", "CASP3", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD46", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDS2", "CDYL", "CEBPZ", "CECR2", "CELF1", "CELF2", "CEP170", "CEP290", "CEP44", "CERK", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHRAC1", "CHUK", "CIP2A", "CISD1", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLIP1", "CLPTM1L", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA3", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPT2", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DARS", "DBNL", "DCAF1", "DCAF7", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DPF2", "DPM1", "DPYSL2", "DSC1", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EGFR", "EHD1", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "ELP4", "EMD", "EML4", "ENAH", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPRS", "ERCC2", "ERCC3", "ERCC4", "ESD", "ESPL1", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOSC2", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FAM91A1", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FKBP10", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXC1", "FOXRED1", "FREM2", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAPDH", "GART", "GBA", "GCC2", "GCDH", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GIGYF2", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNPAT", "GNS", "GOT1", "GOT2", "GPD1L", "GPD2", "GPHN", "GPI", "GPS1", "GRB2", "GRSF1", "GSK3A", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GTPBP4", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HIRA", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF2", "ILK", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF4A", "KIF5B", "KIRREL1", "KLC1", "KMT2A", "KPNA1", "KPNA4", "KPNB1", "KTN1", "LAMB1", "LAMC1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRP2", "LRPPRC", "LRRC59", "LRRC8E", "LRWD1", "LSM2", "LSS", "LTA4H", "LYN", "LZTFL1", "MACF1", "MAD2L1", "MAGT1", "MAP1B", "MAP2K1", "MAP2K4", "MAP4", "MAP4K5", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MEPCE", "MFGE8", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOGS", "MORF4L1", "MOV10", "MPG", "MPI", "MPP1", "MPP2", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVB12A", "MYBBP1A", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO6", "MYO9B", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAPG", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCL", "NCSTN", "ND1", "ND5", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NEU1", "NF1", "NFATC2IP", "NIPBL", "NKRF", "NME1", "NME2", "NME3", "NONO", "NOP2", "NPC1", "NPC2", "NRP1", "NSD1", "NSDHL", "NSF", "NTHL1", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "ORC3", "ORC5", "OTUD7B", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAPSS1", "PARK7", "PARN", "PARP1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA6", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PIGT", "PIK3C2A", "PIN1", "PISD", "PKM", "PKN1", "PKN2", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMPCA", "PMVK", "PNP", "PNPT1", "PODXL", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PURA", "PUS1", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB13", "RAB14", "RAB21", "RAB2A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RALB", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RECQL5", "REL", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RIF1", "RIPK1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF40", "RNMT", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAGC", "RRAS2", "RRBP1", "RRM1", "RRM2", "RTCB", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SASS6", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEL1L", "SERBP1", "SERINC1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SEZ6L2", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SFSWAP", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SKP1", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SMYD2", "SMYD3", "SMYD5", "SNAP23", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPEN", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSR3", "SSR4", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STRAP", "STRN", "STUB1", "STX3", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUPT5H", "SURF1", "SUZ12", "SYNE2", "TAB1", "TACO1", "TAF6", "TALDO1", "TAP1", "TARDBP", "TBC1D4", "TBCA", "TBK1", "TBL1XR1", "TBL2", "TCP1", "TDP2", "TECR", "TELO2", "TERF2IP", "TFAM", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TLN1", "TMED10", "TMEM165", "TMEM43", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRRAP", "TSC2", "TSG101", "TTC19", "TTC26", "TTI1", "TTK", "TUBB", "TUBB2A", "TUBB2B", 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b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:45df2549bf8f4afa20f33061c56a73b427d2d654513982fc0f8ec6280916f2e9 +size 70599 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..50e875358036ad746167f3ffb9eb3aaf07ea003f --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +er 42 83 3.437816867540868 0.0005864241550885 29.17233009708738 87.61893203883496 1.3358083950399515 0.3757472714196316 13.465054065187209 8.223393744963309 2.0429537263872786 0.4010648005920765 5.3617300497203787e-08 0.4978494903048275 0.3974571713547065 0.0571380716972498 1.5214506613391847e-10 +mitochondria 6 10 2.5125329547597657 0.0119867909059987 4.441747572815534 10.567961165048544 1.1937677940164793 0.2159787381789819 2.254231157409949 0.7391563798220593 1.4011905974754153 0.2980089661914649 0.0001046031266164 1.0 1.0 0.0382400085743442 8.104989222609044e-07 +vesicles 69 169 2.4469369194443664 0.0144076052532202 42.101941747572816 169.6626213592233 0.6789633151163722 0.6006686966705359 14.133870910307197 18.74575061031192 1.1351302778834993 0.3922666308151308 3.7325899312640367e-06 0.0831631571470204 0.048100779771128 9.573649443746544e-05 8.51427358209001e-08 +golgi 30 59 2.338468600381462 0.0193629526912244 15.631067961165048 61.19417475728155 0.6692399314943925 0.523533703348586 6.922582002252161 5.868805558877078 1.075539554450533 0.3729249549278102 0.0025228712403731 0.3867386931517215 0.2533609509960167 0.0983363279904071 9.953029542124808e-05 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9ffc48877991845f5a1b318294d8c22502e67e5f --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 94.05882352941177 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..382a8319669c2e079a424fa83007503938673a3a --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e2c479e296b8ba4796fda267d4d46dff83eedda2 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +er 0.5219052580089375 3.4378168675408673 0.0005864241550885 0.0099225780018599 0.0099692106365059 83 Q15392,Q8TCJ2,Q96N66,P04843,O60499,Q9P2W9,P51572,Q8N4V1,O75915,Q9NTJ5,O95470,Q969Q5,O15173,Q9BVG9,Q9NR31,Q96A33,P51151,Q9Y5M8,P27824,Q6DD88,Q16850,Q5HYI8,Q07065,Q9Y6B6,Q9NQC3,P46977,Q8NF37,P00387,Q06136,P61019,O14735,O00264,O96005,P49755,Q13190,Q14739,Q9Y487,Q15363,P48651,O15269,O00400,Q8NHH9 42 +mitochondria 0.77982190913155 2.5125329547597657 0.0119867909059987 0.1853580606668154 0.0816430964349148 10 Q9NVH1,P45880,Q969Q5,P21796,Q9Y277,Q9NR31 6 +vesicles 0.5046743345319566 2.4469369194443664 0.0144076052532202 0.2186334024683845 0.0816430964349148 169 Q15392,P20339,O43633,Q13501,O60499,P05023,Q14145,Q96L92,P51798,O95470,Q15036,O15127,O15173,Q9BTU6,P54920,P62820,Q13277,P51151,O43808,P17612,P02786,P61020,Q93050,O15400,Q9H0U4,P42345,Q8NBN3,P08069,Q5HYI8,Q969T9,Q969E2,Q8IZA0,P20020,Q9UNK0,Q8NF37,O15258,Q9H9H4,O75787,O15126,P00387,Q06481,Q7Z6M1,Q06136,P30825,Q15904,P61019,O14735,Q8IY95,O96005,O00264,P61421,P49755,O95249,Q15758,P04439,Q8IXU6,O60826,O00429,Q13308,P11166,Q15363,Q96A49,Q86Y82,O15269,Q9UBF8,P11279,P51149,O00400,P31751 69 +golgi 0.5388272974667938 2.338468600381462 0.0193629526912244 0.2827987497126793 0.0822925489377039 59 Q9NTJ5,P62820,O15127,P54920,Q9NR31,P40616,P35606,P61026,Q9H0U4,Q8NBN3,Q969E2,Q9Y6B6,Q8IZA0,O15258,O75787,O15126,Q15904,Q5VW38,P61019,O14735,Q9Y3E0,Q9Y678,P49755,Q13190,Q9Y487,Q8IXU6,Q96A49,Q9UBF8,P18085,P36543 30 +membrane 0.4008113005246407 1.937126199766659 0.0527299186988072 0.6018424530417592 0.1612664854873919 82 O60499,P05023,P04920,O15127,Q13277,P08670,P19022,P02786,P08069,Q969E2,P0DP25,Q16513,Q9NQC3,P20020,Q9UQB8,O15126,P48729,P30825,Q15758,P04439,Q13308,P31751 22 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d0cf1932b9671b02f1d6af6d3a46c8ee2ec8ff61 --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AGAP3", "AHCY", "AHSA1", "AKAP12", "AKAP13", "AKAP8L", "AKR1A1", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH9A1", "ALG2", "ANAPC16", "ANKRD17", "ANXA11", "AP2B1", "AP2S1", "APC", "APLP2", "ARF4", "ARF6", 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sha256:953c4920e7e7a04534728ff2c03177cc1fce0035ce2c3113d9ac14224ba545cf +size 80527 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1fe9fc408670ce52b24ceec1048d9069a2b78420 --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,14 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +SNARE protein 8 11 2.879879141696191 0.0039782764156328 4.660194174757281 11.12378640776699 0.9288896561072936 0.3201954718639376 2.5506648592929815 2.745113440103806 1.1546709449924732 0.3042666981599379 1.309094402163559e-06 0.1305522111527444 0.2445730022705269 4.450565670464667e-06 5.837517180193655e-06 +transmembrane signal receptor 7 10 2.6543959267717736 0.0079450543716215 3.266990291262136 7.169902912621359 1.6693846681257831 0.1085289610325799 1.5770125590990791 1.7927217985188668 1.0928815816574815 0.16461969248918 0.0326350405088471 0.0720814043883259 0.2213471409258044 0.183699096822524 0.0778250722651817 +membrane trafficking regulatory protein 6 18 2.5832155630767204 0.009788414273959 4.949029126213592 18.78640776699029 1.0645815505395402 0.2320552342124929 2.3097144002673033 2.893415643517755 1.4460865220385617 0.2677048300346334 0.0052379390540773 0.0266825716175236 0.0919415891551245 0.008923404115777 0.0135499856307104 +secondary carrier transporter 8 16 2.5233985425377026 0.0116226593753874 6.104368932038835 14.6626213592233 1.264699085385324 0.2718921136589474 3.483843477892234 2.781747184831951 1.2916784116683784 0.322278600042778 0.0077238280354757 1.0 0.497470817800254 0.2468458051395524 0.0211829876625836 +mitochondrial carrier protein 5 7 2.394140497752913 0.016659365945937 3.2936893203883497 7.065533980582524 1.4583792806536486 0.1840967072966826 2.0141872967986307 1.116111686789906 1.1161599809390137 0.2507152229846449 5.737823424793828e-06 1.0 0.1180585699575878 0.2731207001200411 1.6279070379868977e-05 +apolipoprotein 4 6 2.3778689260666472 0.0174130143652277 0.6503856041131105 2.437017994858612 0.932382076838194 0.2433812620783314 0.949160692915208 1.2312417090911711 1.6649876261886865 0.2763167407189011 0.0002281841207161 0.0697581245313758 0.1349531130589082 1.972516813028553e-05 4.367834065541858e-05 +glycosidase 4 6 2.357464036042313 0.018400237535231 2.349514563106796 4.621359223300971 -0.2307336370526829 0.2597902373581335 1.0699672244692364 0.6012366681705257 1.6034021241460206 0.2766391836749902 2.090417284066789e-06 0.0331691185540615 2.930872407836843e-05 1.6178346926680584e-07 5.11944457815466e-06 +oxygenase 4 7 2.332156140923156 0.0196924785265799 3.138349514563106 6.771844660194175 1.5409868347565758 0.1477866581414416 1.2914149665013366 1.041089559555361 1.2379399582807478 0.2357869798067575 0.0148145229851571 1.0 0.2070995190727305 0.0195244436529747 0.0052134507581354 +transporter 14 58 2.259346171744388 0.0238618599380864 16.281553398058254 57.34708737864078 1.7781248355514696 0.2510912048406951 6.627271511266295 3.5084386843827997 1.4364723564792363 0.3433005081320681 7.209507500014056e-05 0.0002327170452096 0.0008957475254315 0.0021116550101023 0.000517584433991 +transfer/carrier protein 9 12 2.168343848751596 0.0301325345345258 4.33252427184466 11.024271844660197 0.5751131114698911 0.3717158985009051 2.2946984989028927 1.3525930522279908 1.248808855129494 0.3186564966906889 3.23304802908002e-05 1.0 0.2070995190727305 0.0024379570615939 1.0761884384293304e-05 +primary active transporter 14 20 2.1593672880862385 0.0308216836277324 8.614077669902912 23.45631067961165 1.2392440710771837 0.271771563990288 4.792195908457348 3.1431129799052804 1.4794913205770832 0.3014776193450941 0.0033632287867975 0.0356328568827733 0.1194965359594502 0.0168986737095617 0.0007324740008612 +protein-binding activity modulator 1 6 2.151742194132527 0.0314176649233046 1.529126213592233 4.25 0.2668550947983373 0.5086627191257674 1.193276558571054 0.9441310794299864 0.9807813955882424 0.3127844875765326 0.2082427723091965 0.0963063052639835 0.1837383274168749 0.090818300458346 0.2715157705871365 +calmodulin-related 9 13 2.134861545666673 0.0327723212210384 5.053398058252427 12.385922330097088 1.3935892727836532 0.1814075830019033 2.0222219603900085 1.786979844553702 1.206053991839631 0.2252292235861566 4.335162619001001e-05 0.1135912525516411 0.0016986126979642 0.0002861885476851 1.1237436337996233e-07 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0b99b5c7b201847016f9c0ebc72957b8a4e853c6 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 160, + "title": "Average number of proteins per term", + "value": 13.15 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bebf05be719dae4686782dd03df41ea2381c9e98 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6828f795b04be23526da117485bcaa6d073effb0 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,50 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +SNARE protein 0.8412756027996111 2.879879141696191 0.0039782764156328 0.4715429418200388 0.2359177075572174 11 O95249,Q13190,Q9P2W9,O60499,O15400,Q86Y82,Q13277,Q9UNK0 8 +transmembrane signal receptor 0.808808681960062 2.6543959267717736 0.0079450543716215 0.72092801476935 0.2359177075572174 10 Q15375,O75787,Q99720,P00533,O15173,P15260,P14543 7 +membrane trafficking regulatory protein 0.6667416293273035 2.5832155630767204 0.009788414273959 0.7927566800525909 0.2359177075572174 18 O43731,P24390,Q8WTV0,O00560,Q14108,P11279 6 +secondary carrier transporter 0.6931754924213731 2.5233985425377026 0.0116226593753874 0.8459559795459508 0.2359177075572174 16 Q8TB61,P55011,Q9UBX3,Q9Y6M7,P04920,Q92581,Q15043,O95202 8 +mitochondrial carrier protein 0.8447082258551566 2.394140497752913 0.016659365945937 0.9319798314289728 0.2359177075572174 7 Q9NZJ7,Q70HW3,Q9HC21,Q6NUK1,Q9BSK2 5 +apolipoprotein 0.865792637995706 2.3778689260666472 0.0174130143652277 0.939832603856264 0.2359177075572174 6 P98155,P04114,Q07954,Q9BQE5 4 +glycosidase 0.861132479900875 2.357464036042313 0.018400237535231 0.9487715589406508 0.2359177075572174 6 P06865,Q9BTY2,P04066,P07686 4 +oxygenase 0.8309609909006196 2.3321561409231557 0.0196924785265799 0.9585071210968404 0.2359177075572174 7 P30519,P19021,P09601,Q14534 4 +transporter 0.5335274712754837 2.259346171744388 0.0238618599380864 0.9790200173233772 0.2359177075572174 58 Q567V2,Q92544,P54105,Q15012,P39210,Q9HD45,O60830,Q15070,Q9Y619,Q92973,Q99805,Q9H2D1,Q99595,Q96P70 14 +transfer/carrier protein 0.6887776178253803 2.168343848751596 0.0301325345345258 0.9925186053789258 0.2359177075572174 12 Q9Y5M8,P12235,P12236,O15126,P05141,O15127,O14828,Q969E2,P17900 9 +primary active transporter 0.5836444751985536 2.1593672880862385 0.0308216836277324 0.993322863690576 0.2359177075572174 20 P54709,Q9NS69,O75381,Q8N4H5,Q9H9B4,O96008,Q15758,P05023,P16615,Q04656,O60888,Q9BUN8,Q6P4A7,P20020 14 +protein-binding activity modulator 0.8147676742097105 2.151742194132527 0.0314176649233046 0.9939487225595032 0.2359177075572174 6 Q9NRX5 1 +calmodulin-related 0.6702261763147686 2.1348615456666735 0.0327723212210384 0.9951627941353788 0.2359177075572174 13 Q02818,P80303,Q9BRK5,Q8IYU8,P41208,P0DP25,Q9BPX6,Q14257,O43852 9 +G-protein coupled receptor 0.8811048894238112 1.9386464538859 0.0525444029109023 0.9998224099966916 0.2810997957438713 4 Q8NBN3 1 +amino acid transporter 0.8234908136482825 1.9373202231070876 0.0527062117019758 0.9998271973805338 0.2810997957438713 5 Q96QD8,O14925,O75915,P30825 4 +phospholipase 0.7399070117902538 1.8092400358842908 0.0704137202797392 0.99999155979848 0.3218460516082741 6 Q8IV08 1 +heterotrimeric G-protein 0.7265246700758065 1.746708625150985 0.0806878934833781 0.9999985741405846 0.3257000487649373 6 Q6DD88,P04899,Q8NHH9,P08754 4 +oxidase 0.6013252738704925 1.740064919137808 0.0818476193110124 0.999998834902305 0.3257000487649373 13 O75880,P14406,Q15800,Q8NB78,Q6ZRP7,P13073 6 +voltage-gated ion channel 0.9190163934426194 1.6613656741477172 0.0966400273938941 0.9999999133567116 0.3562275316611141 3 P45880,P21796 2 +galactosidase 0.976728941330712 1.655601621589015 0.0978025215856819 0.9999999294889096 0.3562275316611141 2 P06280 1 +serine protease 0.5523535720090658 1.6548123343756238 0.0979625712068064 0.9999999314623296 0.3562275316611141 16 Q9H3G5,P10619,Q9HB40,O14773,Q16740 5 +ion channel 0.7474953399669051 1.6047617929248943 0.1085462372261381 0.999999989629216 0.3695191054506829 5 Q9C0H2,P51790 2 +major histocompatibility complex protein 0.8940983606557321 1.562502389934109 0.1181696832901821 0.9999999981735656 0.3702132069056633 3 P04439,P10321 2 +cell adhesion molecule 0.9524745984922978 1.5551622650348211 0.1199074288251687 0.9999999986679 0.3702132069056633 2 Q08722 1 +glycosyltransferase 0.4984892607711253 1.5534348092931498 0.1203192922443405 0.9999999987640218 0.3702132069056633 21 Q9BV10,P04843,Q9BT22,Q86SF2,Q68CQ7,Q10471,Q10472,Q8NBN7,Q16739,P46977 10 +metalloprotease 0.4821967590849791 1.421244244916728 0.1552457661036452 0.9999999999981084 0.4314414265786471 26 O75844,P42892,P02786,P55786,Q9UIQ6 5 +membrane traffic protein 0.4492334593123335 1.4026731625570437 0.1607143237327208 0.9999999999993308 0.4358354541904294 55 O43633,Q00765,O43493,Q9UPT5,P51572,Q9NX40,P54920,P40855,P43307,A6NIH7,Q92673,P49257,P20645,Q99523,Q9HD26,Q10567,Q9H223,Q8WUM4,O00429,P11717,Q12907,O60313,Q9H4M9,Q96CW1 24 +kinase 0.4722883746182963 1.3645298606890084 0.1724008627375295 0.9999999999999292 0.4524009148795998 20 P52789,Q8TCT0,Q8WVC6,P35790,Q9BRR6 5 +aspartic protease 0.8301874820885911 1.307771867472136 0.1909506988980451 0.999999999999998 0.4749203115985922 3 Q8TCT8 1 +immunoglobulin receptor superfamily 0.8810226155358992 1.259646331305143 0.2077969739389309 1.0 0.4929280359259671 2 Q5ZPR3 1 +decarboxylase 0.8168993663959419 1.2547969182363257 0.2095524916232887 1.0 0.4929280359259671 3 Q8NBZ7 1 +protein modifying enzyme 0.4595562066264723 1.2463523186746226 0.2126350781215549 1.0 0.4929280359259671 27 O00462,Q6P2P2,P13674,Q92791,Q9UMR5,O60725,P50897,P33908 8 +methyltransferase 0.5077299820113217 1.1314591793994628 0.2578618752954187 1.0 0.5342932150538537 12 Q9BV86,Q9H8H3 2 +integrin 0.8289085545722863 1.0470706994726686 0.2950669718999519 1.0 0.5749364420624281 2 P06756 1 +kinase activator 0.6501238143366325 0.9765518010940694 0.3287910908385456 1.0 0.611704355048457 4 P46020 1 +cysteine protease 0.418237064467459 0.9213194329007312 0.356883678258804 1.0 0.6158606431762558 28 Q99538,P53634,Q96FW1,Q92820,P07858 5 +small GTPase 0.4499936478089205 0.7544667983146375 0.4505689745859309 1.0 0.6931830378245091 11 Q9HB90,Q8IXI1,P11233,P11234 4 +ATP synthase 0.3785514836757691 0.6708820577407038 0.5022956672607337 1.0 0.7275480771936453 19 O75964,Q9Y487,Q93050,Q15904,P56134 5 +acyltransferase 0.4242368679683575 0.666163029828063 0.5053069006721564 1.0 0.7275480771936453 13 Q8NF37,Q8NCC3,P53611,P35610,P23786,P49356 6 +oxidoreductase 0.380345874238374 0.614043214175841 0.5391867712366825 1.0 0.7437058913609413 41 O14949,Q15067,P09622,O43169,O96000,Q9Y6M9,O95831,P00403,Q86Y39,P16435,O43676,Q08431,O95169,P03915 14 +tubulin 0.4886773875943626 0.6033890978648769 0.5462498731287617 1.0 0.7470083735094177 6 P04350,Q9BVA1,Q9BUF5,P07437,P68371 5 +ATP-binding cassette (ABC) transporter 0.4632651967679662 0.5437282805411953 0.5866284683708787 1.0 0.7765752716092093 7 Q9NVZ3,Q03518,O14678 3 +transferase 0.3673830425638241 0.5108305091040006 0.6094697438782797 1.0 0.7928061708985752 31 Q9NRN7,Q99735,Q06520,P48651,O14735,Q2TAA5,O15217,Q7LGA3,Q9BVG9,O43505,P43490 11 +chaperone 0.3238073753207717 0.3560773482504062 0.7217826404261629 1.0 0.8401596093724164 66 O14657,Q9NVH1,P49321,Q9Y680,Q9Y2R0,O15260,P62942,P27824,Q99543,Q7KZN9,P78318,Q96KC8,Q96JJ7,Q15526,Q9NWM8,P07237 16 +G-protein 0.4501312335958072 0.3112928467210015 0.7555780048258929 1.0 0.8513554983953723 5 P40616,Q9NTK5,P18085,P08240 4 +nucleic acid metabolism protein 0.426509186351704 0.2284919524246473 0.8192638117040476 1.0 0.8917157134193716 5 Q9Y2W1,Q96FV9,P49750,Q9UGR2 4 +tight junction 0.4749262536873037 0.0648778890063789 0.9482712255137384 1.0 1.0 2 Q07157 1 +Hsp90 family chaperone 0.3666775992128534 0.0392255161929729 0.9687105903078506 1.0 1.0 4 P14625,Q12931,P08238 3 +phosphatase modulator 0.3449294387922472 0.0360643383685772 0.9712310576780334 1.0 1.0 6 Q9UPN7,P30153,O14974,P30154,Q96QC0 5 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6e690ef7c77ba121e75972f56ba76b63c6cba9b0 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "immunoglobulin receptor superfamily", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "serine/threonine protein kinase receptor", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANKRD17", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOB", "APOBEC3C", "APOL2", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARHGAP1", "ARHGDIA", "ARHGEF1", "ARIH1", "ARIH2", "ARL1", "ARL6IP5", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC3", "ASF1B", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATL2", "ATL3", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BAG6", "BAIAP2", "BAP18", "BAZ2A", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCLAF1", "BDH2", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPHL", "BPNT1", "BRCA1", "BRD7", "BRD9", "BRIX1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASP2", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX4", "CBX8", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CEP170", "CERK", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIP1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT4", "CNP", "COA3", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPD", "CPE", "CPOX", "CPSF1", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CUTC", "CYB5B", "CYB5R3", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DEK", "DENR", "DERL1", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DPF2", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DSC1", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC4", "EXOC5", "EXOC7", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "FAHD1", "FAM3C", "FAM98A", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GINS1", "GINS2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLT1B", "GOPC", "GOSR1", "GOT1", "GOT2", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR107", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM3", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTPBP1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HP1BP3", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HTRA2", "HUWE1", "IAH1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "ISCU", "ISOC1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L3HYPDH", "LAMB1", "LAMC1", "LAMP1", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LRP1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8E", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSS", "LTN1", "LYAR", "LYPLA1", "LYPLAL1", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MASTL", "MAT2A", "MAT2B", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED12", "MED17", "MED24", "MED4", "METAP2", "METTL1", "METTL13", "METTL7A", "MFGE8", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL58", "MRPL9", "MRPS15", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCBP1", "NCDN", "NCK1", "NCOA5", "ND1", "ND5", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NENF", "NEU1", "NF1", "NFS1", "NHP2", "NID1", "NIP7", "NIPBL", "NISCH", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PAM", "PANK4", "PARG", "PARN", "PARP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF14", "PHF3", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KB", "PICALM", "PIK3C2A", "PIN1", "PINX1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPT1", "PODXL", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RALB", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL5", "REEP4", "REEP5", "REL", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT1", "RHOT2", "RIF1", "RIPK1", "RNASEH2A", "RNF14", "RNF2", "RNMT", "RNPS1", "ROCK2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAGC", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "S100A10", "S100A11", "SACM1L", "SAE1", "SALL2", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERINC1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC6", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMPDL3A", "SMYD2", "SMYD3", "SNAP23", "SNAP47", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STK4", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL3", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TERF2IP", "TES", "TFCP2", "TFG", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM259", "TMEM87A", "TMOD1", "TMOD3", "TMPO", "TMX2", "TMX3", "TNPO1", 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sha256:b5759d2afe9afa8d61617506b770ea81264e69563a544aabcc15fa0e28938df5 +size 139073 diff --git a/pharos_dto/basic/plot_8.png b/pharos_dto/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..270615aee8ad1f85ce9cdf697c3f601fc917321a --- /dev/null +++ b/pharos_dto/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:184d1e203fec25404b2cea1a5e1b1adc39b162eaaad1c1987105d631a17d5164 +size 129439 diff --git a/pharos_dto/basic/plot_9.png b/pharos_dto/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..9d9b8e8ff32ee51fd826a93d2cfe21a96141e096 --- /dev/null +++ b/pharos_dto/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4729aac24f033b39b52e5f599558c3484c3e709019e977cf435dd9870474de23 +size 128395 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..87629abe92e9f02c73065cb2c6b4a7432d683c61 --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:485cb662ed80a758c9e3c0f12b1a2b6ca2a79363e4065652d40c24832456d636 +size 160285 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2ef12ff4c684855538bf06f08a6267c6dffa6c03 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,14 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +SLC superfamily of solute carriers 26 47 3.189438214307685 0.0014254960762083 18.888349514563107 44.33009708737864 2.1618907004737498 0.1690913715307362 9.633686860107934 5.825351940723624 1.7350998035598977 0.2760301582542676 4.231240708034901e-09 0.587145575543033 0.0080863475465696 0.0004762934947769 4.9798877483656784e-08 +Transporter 62 186 3.1349628860891383 0.001718758550864 57.59466019417476 188.27912621359224 1.4971900036635353 0.4160578104205245 21.77919356765414 18.57070590158326 1.926868489654782 0.421013047757716 3.456032289359342e-16 0.0020723570701327 1.4813588624641798e-05 4.813430227564482e-10 1.4176840955597331e-14 +SLC25 family of mitochondrial transporters 11 20 2.9277210348251104 0.0034145625858088 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 1.2287824403383438e-08 1.0 0.048990890514732 0.0002354199804627 9.150174799393413e-08 +SNARE protein 8 11 2.879879141696191 0.0039782764156328 4.555825242718447 10.6626213592233 0.9494792984446184 0.3117420251981136 2.5225757464631977 2.583604188764985 1.1633177546874711 0.3031193116521645 6.585458948037163e-07 0.1221118561195742 0.2297987482657219 2.6393235185604498e-06 2.980512657152744e-06 +Mitochondrial nucleotide transporter subfamily 7 9 2.5902639149174176 0.0095902377286658 4.216019417475728 9.065533980582524 1.5870110662923598 0.1668197633609344 2.720728714423222 1.1029864386277723 1.1616247375257451 0.2431804664231326 3.396553066670868e-08 1.0 0.0088504827764808 0.000371706641515 1.3888266358141086e-07 +Calcium-binding protein 10 18 2.4827832604132847 0.0130360377853353 6.135922330097087 18.021844660194176 1.3650952896045327 0.2072953623045914 2.3371152398743247 2.2037057261181348 1.237653756718734 0.2545563939054063 0.0004561421768018 0.0204708743585679 0.0009611330378982 0.0007908116200209 8.9707025860296e-06 +Receptor 16 30 2.3211008949804217 0.0202813991037271 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 0.003685923721347 0.0919108957066336 0.271213554068588 0.1145603052268967 0.0051834533037316 +Membrane trafficking regulatory protein 4 20 2.302687021670803 0.0212964589339237 4.560679611650485 20.218446601941743 0.5159227056829229 0.4386866271320015 2.6094874555832708 2.7661001804550924 1.1256129588723178 0.3307884378613797 0.0373709737660068 0.0204708743585679 0.0720571885403784 0.0247625444605767 0.0707827064406983 +Intracellular calcium-sensing protein 9 15 2.2156535466142566 0.026715238616239 5.330097087378641 14.50728155339806 1.3338669185027796 0.2094989649985028 2.1356354617596836 1.8597539737980884 1.176586593960994 0.2465515447823433 0.0002374402003709 0.1430638950507344 0.0034893000144238 0.0009447024772989 1.6299327440176916e-06 +Calmodulin 9 15 2.2156535466142566 0.026715238616239 5.330097087378641 14.50728155339806 1.3338669185027796 0.2094989649985028 2.1356354617596836 1.8597539737980884 1.176586593960994 0.2465515447823433 0.0002374402003709 0.1430638950507344 0.0034893000144238 0.0009447024772989 1.6299327440176916e-06 +Ion channel 3 8 2.1542839561205325 0.0312179102878349 2.9611650485436893 8.271844660194175 0.2358363301857469 0.3871382019519256 1.7759030526384678 1.9242659665051836 1.1979225459677625 0.2963208074862355 0.114653656389487 0.1991580424676108 0.3593428278464597 0.0998367022916053 0.1829577777968287 +Esterase 2 9 2.1415270614034347 0.0322315585865702 2.4199029126213594 10.856796116504857 0.6548503739556798 0.3454832165784889 1.4749994208625692 1.2546524785480109 1.099568757577031 0.2732488393636652 0.0249420258170647 0.0742352733278267 0.0100519320580488 0.0062267265321947 0.0397387250697101 +P-type ATPases 4 5 2.024601251842612 0.0429083256182216 3.2815533980582523 6.757281553398058 0.5021561418998097 0.3946150755400491 1.82441625577419 1.518277124105495 1.19746001211325 0.3286800838620415 0.0574232775214491 1.0 1.0 0.0983610682747182 0.0034992238505004 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..67098205c5a824bf19bb8398fbdbeab41c6f7512 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 1995, + "title": "Average number of proteins per term", + "value": 3.1092731829573936 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a31da1800e447e8444d50ddd354ae2b460100f2e --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5fa9620e0e23e2e684e86c4ca7545361c135634f --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,60 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +SLC superfamily of solute carriers 0.6862754880292982 3.189438214307685 0.0014254960762083 0.9419176564757632 0.3972912005326817 47 Q9HC07,Q96QD8,P55011,Q70HW3,P05141,Q9Y6M7,Q9Y6C9,P04920,Q8NEW0,Q9HC21,P14672,Q9Y619,Q8TB61,P08195,Q6NUK1,P30825,Q7L0J3,Q92581,Q9H2D1,Q9BSK2,Q9NZJ7,P12235,P12236,Q9UBX3,P11166,O95202 26 +Transporter 0.5749493484993762 3.1349628860891383 0.001718758550864 0.9676736772705606 0.3972912005326817 186 O43731,Q9HC07,O43493,Q96QD8,P55011,O60499,Q9P2W9,Q70HW3,P05023,P05141,Q9Y6M7,Q9Y6C9,Q15070,P04920,Q15043,Q99805,Q13277,Q8NEW0,Q15012,P24390,Q93050,Q9HD45,O15400,O00560,Q9HC21,P14672,Q9Y619,Q92673,Q9UNK0,Q92544,Q8TB61,P08195,P16615,Q04656,Q9Y3B3,Q99523,Q6NUK1,P30825,Q7L0J3,Q92973,Q92581,P17900,Q9H2D1,Q9BSK2,O95249,Q13190,Q9NZJ7,P51809,P12235,P54105,P12236,Q9Y487,O43760,Q03518,Q9UBX3,Q8NFH4,Q15363,P11166,Q86Y82,P11279,O95202,Q9BQE5 62 +SLC25 family of mitochondrial transporters 0.7009736508517049 2.9277210348251104 0.0034145625858088 0.9989123207605284 0.3972912005326817 20 P12235,P12236,Q70HW3,P05141,Q9HC21,Q6NUK1,Q9UBX3,Q9Y619,Q9H2D1,Q9BSK2,Q9NZJ7 11 +SNARE protein 0.8412756027996111 2.879879141696191 0.0039782764156328 0.9996482150692864 0.3972912005326817 11 O95249,Q13190,Q9P2W9,O60499,O15400,Q86Y82,Q13277,Q9UNK0 8 +Mitochondrial nucleotide transporter subfamily 0.8265398802813825 2.5902639149174176 0.0095902377286658 0.99999999552544 0.3972912005326817 9 P12235,P12236,Q70HW3,Q9HC21,Q6NUK1,Q9H2D1,Q9BSK2 7 +Calcium-binding protein 0.6507619775695699 2.4827832604132847 0.0130360377853353 0.9999999999957236 0.3972912005326817 18 Q02818,P43307,P80303,Q9BRK5,Q8IYU8,P41208,P0DP25,Q9BPX6,Q14257,O43852 10 +Receptor 0.6026222831398501 2.3211008949804217 0.0202813991037271 1.0 0.3972912005326817 30 Q567V2,O75381,O75787,Q9UQB8,Q8WTV0,P39210,P05556,P57105,A6NIH7,P11717,Q9NRX5,Q14108,P15260,P20645,Q9BUN8,Q13641 16 +Membrane trafficking regulatory protein 0.6047358808866952 2.302687021670803 0.0212964589339237 1.0 0.3972912005326817 20 O43731,P11279,O00560,P24390 4 +Intracellular calcium-sensing protein 0.6567913952444561 2.2156535466142566 0.026715238616239 1.0 0.3972912005326817 15 Q02818,P80303,Q9BRK5,Q8IYU8,P41208,P0DP25,Q9BPX6,Q14257,O43852 9 +Calmodulin 0.6567913952444561 2.2156535466142566 0.026715238616239 1.0 0.3972912005326817 15 Q02818,P80303,Q9BRK5,Q8IYU8,P41208,P0DP25,Q9BPX6,Q14257,O43852 9 +Ion channel 0.7641740623855201 2.1542839561205325 0.0312179102878349 1.0 0.3972912005326817 8 Q9C0H2,Q4KMQ2,P51790 3 +Esterase 0.7338747914935473 2.1415270614034347 0.0322315585865702 1.0 0.3972912005326817 9 P50897,Q9UMR5 2 +P-type ATPases 0.8438320209973755 2.0246012518426117 0.0429083256182216 1.0 0.3972912005326817 5 P16615,Q04656,P20020,P05023 4 +Phosphatase inhibitor 0.7569426878504968 1.8882837354257904 0.0589878696176437 1.0 0.3972912005326817 6 Q99733,P55209 2 +Oxygenase 0.7348925316005834 1.7858535855036024 0.0741229678070611 1.0 0.3972912005326817 6 P19021,Q14534 2 +G-protein 0.5292054167415932 1.7795607566735854 0.0751478734126886 1.0 0.3972912005326817 29 Q14344,P62070,Q6DD88,Q9HB90,P55060,O00429,P08754,P04899,O60313,P11234,P11233,Q8IXI1,Q8NHH9,Q96P70 14 +Heterotrimeric G-protein 0.7265246700758065 1.746708625150985 0.0806878934833781 1.0 0.3972912005326817 6 Q6DD88,P04899,Q8NHH9,P08754 4 +Signaling 0.5572700848490066 1.6865560245751663 0.0916887538144959 1.0 0.3992079321691926 16 Q96JJ3,O15173,Q99627,O00264,Q8IZ81,P43490 6 +Phosphatase modulator 0.6377267690647714 1.6495838866212724 0.0990280728949892 1.0 0.4070288902285709 9 Q99733,P55209 2 +Glycosidase 0.8097485367778436 1.646164623965241 0.0997298704024949 1.0 0.4070288902285709 4 P06865,P07686 2 +Galactosidase 0.9685349065880036 1.621686049415776 0.1048705873638831 1.0 0.4134052565528837 2 P16278 1 +TK group 0.6664708104613555 1.5548668838308703 0.119977775831455 1.0 0.427551284008901 7 P08069,Q15375,P00533 3 +Lipase 0.8806459522957094 1.508981108093672 0.1313036107049252 1.0 0.4432951399514544 3 Q8NCC3 1 +Glycosyltransferase 0.5225188971595057 1.46016986985536 0.1442433938655087 1.0 0.4596894101624441 16 Q9BV10,P04843,Q9BT22,Q86SF2,Q10471,Q8N128,Q10472,Q16739,P46977 9 +Chloride channel family 0.9121599475581778 1.388170462151852 0.1650851444468637 1.0 0.4910374478812186 2 P51790 1 +Hydrolase 0.3612807964039902 1.3463233262921728 0.1781982662501813 1.0 0.5050920004490764 95 Q9UMR5,Q5T9A4,Q99519,Q08431,Q969T7,Q9NVI7,Q8NCC3,Q9NPH0,P50897,P15586,Q92484,P16278,P06865,P38571,P07686,P11117,Q8IWA4,P10253,Q9Y251,O00462,Q96C86,P10586,Q9NX62 23 +Class I transporters 0.9013438216978038 1.3434505066715507 0.1791261419587406 1.0 0.5050920004490764 2 P11166 1 +SLC2 family of hexose and sugar alcohol transporters 0.9013438216978038 1.3434505066715507 0.1791261419587406 1.0 0.5050920004490764 2 P11166 1 +SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) 0.8928220255653994 1.3082668430262914 0.1907828171730528 1.0 0.5172893587453338 2 P30825 1 +Small GTPase 0.4659068097985671 1.3080994412118074 0.1908395829757221 1.0 0.5172893587453338 22 Q9HB90,P55060,O00429,O60313,P11234,Q8IXI1,P11233,Q96P70 8 +Acyltransferase 0.5840757708769873 1.2505635827249604 0.2110937441065732 1.0 0.5378442139113838 8 Q8NF37,P53611,P35610,P49356 4 +SLC4 family of bicarbonate transporters 0.8698787282858071 1.213854535779189 0.2248032766875438 1.0 0.554099263416208 2 P04920 1 +Miscellaneous SLC25 mitochondrial transporters 0.8695509668961 1.2125098933338498 0.2253172578196616 1.0 0.554099263416208 2 Q9NZJ7 1 +Methyltransferase 0.5272416825848969 1.204211414666594 0.2285078752103606 1.0 0.5578293296540524 11 Q9BV86,Q9H8H3 2 +Extracellular structure 0.5462237685387197 1.15933056010627 0.24632146955415 1.0 0.578811933757985 9 Q92791,Q32P28,Q5KU26 3 +Ca2+-ATPases 0.854146181579821 1.1494757745738764 0.2503598504168274 1.0 0.5841729843059307 2 P16615 1 +Na+/K+-ATPases 0.8430022943297277 1.1041081252920664 0.2695462370353572 1.0 0.5969547240681259 2 P05023 1 +SLC35 family of nucleotide sugar transporters 0.8393969190429555 1.0894786060889683 0.2759428841476459 1.0 0.6004817529530608 2 Q8TB61 1 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.7347540983606275 0.9306763456558282 0.3520210091613784 1.0 0.6759209944917709 3 P53007,Q9UBX3 2 +PI3/PI4 kinase family 0.793182563094084 0.9047069395289214 0.3656206637416783 1.0 0.6842525555015463 2 Q9BTU6 1 +Oxidase 0.4233334700082474 0.8566111436101447 0.391659825037056 1.0 0.7135720099990198 17 O15260,P14406,Q15800,O43169,Q15526,Q6ZRP7 6 +Phosphodiesterase 0.7114754098360644 0.8410170270056284 0.4003383956732342 1.0 0.7230327622046189 3 O43924,Q92484 2 +SLC12 family of cation-coupled chloride transporters 0.7538511963290894 0.7531436749828534 0.4513635817263601 1.0 0.7562407025875912 2 P55011 1 +Lipid kinase 0.5332788410108998 0.6459941748421273 0.5182831279137661 1.0 0.8002901239844917 5 Q8TCT0 1 +Protease inhibitor 0.4095914983235147 0.6133391501242388 0.5396521118016824 1.0 0.814667847858942 14 Q06481,P07942,P05067,Q5ZPR3 4 +Tubulin 0.4886773875943626 0.6033890978648769 0.5462498731287617 1.0 0.8193748096931426 6 P04350,Q9BVA1,Q9BUF5,P07437,P68371 5 +V-type ATPase 0.4723918667188593 0.5875660939018239 0.5568235749597592 1.0 0.8241989910351609 7 Q93050,Q9Y487 2 +SRPK family 0.684365781710909 0.5062916581477297 0.6126519181925778 1.0 0.8532718544334835 2 P78362 1 +Cysteine protease 0.3569191232948411 0.4233819786232812 0.6720165911427567 1.0 0.8914865712350559 44 Q99538,P53634,Q96FW1,Q8NHP8,Q92820,P07858,Q13510 7 +Metalloprotease 0.3516359834006795 0.3710527195504737 0.7105982654853831 1.0 0.9040133583607586 38 O75844,P42892,P02786,P55786,Q9UIQ6 5 +SET domain 0.4640403917669733 0.3631353036501266 0.7165038135449413 1.0 0.9051326152281208 5 Q9NRG4 1 +Protease 0.3063519683220577 0.3604889828493015 0.7184814940155988 1.0 0.905375762275778 116 O75844,Q9H3G5,Q9UIQ6,Q96FW1,P10619,Q9HB40,P07858,P02786,P53634,Q92820,Q9NZ08,Q13510,Q99538,Q8NHP8,Q92643,P67812,P42892,P55786,O14773,Q8TCT8 20 +F-type and V-type ATPases 0.3357643767388372 0.1819892467909462 0.855591164799963 1.0 0.9402612423265408 14 Q93050,P56134,Q9Y487 3 +Extracellular matrix glycoprotein 0.4008135822427867 0.1471695602228566 0.8829981863720096 1.0 0.9415515031102848 5 Q32P28 1 +CDK1 subfamily 0.5103244837758015 0.1011156715686453 0.9194586376947944 1.0 0.9583516660453112 2 P06493 1 +Chromodomain 0.4485245901639333 0.0824503748729837 0.9342885790212428 1.0 0.9652541248821228 3 P83916,P45973 2 +Reductase 0.2983224028074827 0.051993975025274 0.9585334941555153 1.0 0.9741628847589046 17 O95881,Q14739,Q9UDW1,P00374 4 +Hsp90 family chaperone 0.3666775992128534 0.0392255161929729 0.9687105903078506 1.0 0.9785203178046388 4 P14625,Q12931,P08238 3 +Kinase activator 0.3421916010498618 0.0027301329041564 0.9978216718129078 1.0 1.0 5 P20248,Q16543,P14635,O95067 4 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ef10e9664ece25d024fb595b057ff043967715d8 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L9, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AK1 subfamily", "AK2 subfamily", "AKT family", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family D member 4", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent DNA helicase Q5", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Abl interactor 1", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acid sphingomyelinase-like phosphodiesterase 3a", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 2/3 complex subunit 5", "Actin-related protein 3", "Activin receptor type-1b", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Adenylyl cyclase-associated protein 2", "Adhesion class", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amyloid-beta A4 protein", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Anion exchange protein 2", "Anion exchangers", "Ankyrin repeat and SAM domain-containing protein 1A", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atlastin-3", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical SLC22B subfamily", "Atypical group", "Aurora kinase a", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Beta-mannosidase", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, cytosolic", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 4", "Bromodomain-containing protein 7", "Bromodomain-containing protein 9", "Butyrophilin subfamily 2 member A1", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK2 family", "CAMKL family", "CAP-Gly domain-containing linker protein 1", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 4", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CD276 antigen", "CD97 antigen", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CHK1 subfamily", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-regulated heat-stable protein 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calpain-5", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-2", "Caspase-3", "Cat eye syndrome critical region protein 2", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cathepsin B", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell division cycle protein 20 homolog", "Cell surface glycoprotein MUC18", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Ceramide glucosyltransferase", "Ceramide kinase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 4", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Copper-transporting ATPase 1", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Coronin-7", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cu+-ATPases", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-A2", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytokine receptor", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA dC->dU-editing enzyme APOBEC-3C", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA repair endonuclease XPF", "DNA repair protein complementing XP-C cells", "DNA replication complex GINS protein PSF1", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyribonuclease-2-alpha", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Desmocollin-1", "Desmocollin-2", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 4", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase listerin", "EGFR family", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelial protein C receptor", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Epidermal growth factor receptor", "Epigenetic regulator", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Esterase", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FAK family", "FRAP subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Flap endonuclease 1", "Flavin reductase (NADPH)", "Focal adhesion kinase 1", "Folate transporter 1", "Forkhead box protein C1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GDP-mannose 4,6 dehydratase", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit beta", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate dehydrogenase 1-like protein", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi pH regulator family", "Golgi ph regulator b", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "H/ACA ribonucleoprotein complex subunit 3", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Heparanase", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone chaperone ASF1B", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SETD7", "Histone-lysine N-methyltransferase SMYD3", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "INSR family", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-3", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inhibitor of nuclear factor kappa-b kinase subunit beta", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 1 receptor", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon gamma receptor 1", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KHS subfamily", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIFC1", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lactadherin", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Legumain", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Leukocyte elastase inhibitor", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosomal-associated transmembrane protein 4A", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAP7 domain-containing protein 1", "MAPK family", "MAST family", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MST subfamily", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA", "Mediator of RNA polymerase II transcription subunit 12", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma-associated antigen D2", "Membralin", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Methyltransferase-like protein 7A", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 3", "Mitogen-activated protein kinase kinase kinase kinase 5", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "Myotubularin-related protein 6", "N-acetyl-D-glucosamine kinase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 50", "N-lysine methyltransferase SMYD2", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADH-ubiquinone oxidoreductase chain 5", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neurofibromin", "Neurolysin, mitochondrial", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 3", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "OCIA domain-containing protein 1", "OTU domain-containing protein 4", "OTU domain-containing protein 7B", "Obg-like ATPase 1", "Occludin", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P53-like transcription factor", "PAKA subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 3", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PEK family", "PH-interacting protein", "PHD finger protein 14", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PITSLRE subfamily", "PKA family", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Paxillin", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-glycine alpha-amidating monooxygenase", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phospholipase", "Phospholipase A-2-activating protein", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylase b kinase regulatory chain family", "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform", "Phosphorylated adapter RNA export protein", "Phosphoserine phosphatase", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presequence protease, mitochondrial", "Primase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable helicase with zinc finger domain", "Probable leucine--tRNA ligase, mitochondrial", "Probable serine carboxypeptidase CPVL", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl 3-hydroxylase 3", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein FRG1", "Protein HIRA", "Protein LSM14 homolog B", "Protein Mpv17", "Protein NDRG3", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein VAC14 homolog", "Protein Wiz", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c delta type", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Proto-oncogene c-Rel", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIPK family", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding protein", "RNA helicase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-2", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-alpha serine/threonine-protein kinase", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related GTP-binding protein C", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Ras-related protein Ral-B", "Reader", "Receptor", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 2", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC61 Molybdate transporter family", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLC9 family of sodium/hydrogen exchangers", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "STKR Type 1 subfamily", "STKR family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "Sal-like protein 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Secretory carrier-associated membrane protein 4", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Separin", "Septin-2", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine incorporator 1", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk1", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase greatwall", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase tbk1", "Serine/threonine-protein kinase tousled-like 2", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 6 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin B8", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sialidase-1", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium-coupled neutral amino acid transporter 2", "Sodium-dependent HCO3- transporters", "Sodium/hydrogen exchanger 6", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 9", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 2, facilitated glucose transporter member 4", "Solute carrier family 25 member 33", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sortilin-related receptor", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 1", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptic vesicle glycoprotein 2A", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 47", "Syntaxin-10", "Syntaxin-12", "Syntaxin-18", "Syntaxin-3", "Syntaxin-5", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 10B", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TLK family", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thyroid adenoma-associated protein", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Torsin-1B", "Trafficking protein particle complex subunit 4", "Trans-Golgi network integral membrane protein 2", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription initiation factor TFIID subunit 6", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor p66-alpha", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation initiation factor", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 4", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-3 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tuberin", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Type II PI4K subfamily", "Type II cytokine receptor", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase lyn", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm6", "UDP-glucose:glycoprotein glucosyltransferase 1", "UDP-glucuronic acid decarboxylase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 33", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 82", "Winged helix/forkhead transcription factor", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7B", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 7", "Zinc transporter ZIP14", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "tRNA pseudouridine synthase A"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT9", "ACOX1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG12", "ALYREF", "ANAPC1", "ANGEL1", "ANKS1A", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOBEC3C", "APOL2", "APP", "ARCN1", "ARFIP1", "ARHGDIA", "ARIH1", "ARIH2", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASF1B", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "BAG6", "BAIAP2", "BAX", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCLAF1", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRD9", "BRIX1", "BTN2A1", "BUB1B", "BUB3", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASP2", "CASP3", "CBL", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2BP2", "CDC20", "CDC37", "CDC40", "CDC42", "CDC45", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2AIP", "CEBPZ", "CECR2", "CEP170", "CERK", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIP1", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT4", "CNP", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CYB5B", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCPS", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DENR", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIS3", "DLD", "DLGAP5", "DLST", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DSC1", "DSC2", "DSC3", "DSG2", "DSP", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENO2", "EPHA7", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERC1", "ERCC4", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC4", "EXOC5", "EXOC7", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FNTB", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GCAT", "GCFC2", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GINS1", "GINS2", "GLB1", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNPDA1", "GNS", "GOSR1", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR107", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSPT1", "GSR", "GSS", "GTF3C3", "GTPBP1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HPSE", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "LAMB1", "LAMC1", "LAMP1", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LTN1", "LYN", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4K5", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MASTL", "MAT2A", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED12", "METTL1", "METTL7A", "MFGE8", "MFN1", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MIPEP", "MMS19", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL14", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL9", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCBP1", "NCL", "NCOA5", "ND1", "ND5", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB1", "NDUFB4", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS7", "NEDD4L", "NEK9", "NEU1", "NF1", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OLA1", "OPA1", "ORC3", "ORC5", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "P3H1", "P3H3", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAIP1", "PAK2", "PAM", "PANK4", "PAPSS1", "PARG", "PARK7", "PARN", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PINX1", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPT1", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKACA", "PRKAG1", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSPC1", "PSPH", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPRF", "PUDP", "PUM1", "PURA", "PUS1", "PWP1", "PXN", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGGTB", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RALB", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "RECQL5", "REEP4", "REEP5", "REL", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT1", "RHOT2", "RIPK1", "RNASEH2A", "RNF14", "RNH1", "RNPS1", "ROCK2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAGC", "RRAS2", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "S100A10", "S100A11", "SAE1", "SALL2", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERINC1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMN1*", "SMPDL3A", "SMYD2", "SMYD3", "SNAP23", "SNAP47", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORL1", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK26", "STK4", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TAP1", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM165", "TMEM259", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM3", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TROVE2", "TSC2", "TSFM", "TSG101", "TST", "TSTA3", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWISTNB", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UCHL5", "UCK2", "UGCG", "UGGT1", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP28", "USP33", "USP39", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP3", "UTP6", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VRK1", "VRK3", "WARS", "WDHD1", "WDR1", "WDR33", "WDR4", "WDR82", "WIZ", "XAB2", "XPC", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7B", "ZCCHC11", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF281", "ZNF622", "ZW10", "ZYX"], "leading_proteins": ["ACP2", "ACP6", "ALG1", "ALG12", "ANO6", "APLP2", "APOL2", "APP", "ASAH1", "ATAD3A", "ATAD3B", "ATL2", "ATL3", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5J2", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP7A", "BAIAP2", "CALM3", "CALU", "CBX1", "CBX5", "CCNA2", "CCNB1", "CCNB2", "CD276", "CDC37", "CDK1", "CERK", "CETN2", "CLCN3", "CLNS1A", "COLEC12", "COPS8", "COX7A2", "CPVL", "CSE1L", "CTSA", "CTSB", "CTSC", "CYB5B", "DCPS", "DERL1", "DHFR", "DNM1L", "ECE1", "EGFR", "ELMO2", "ELMOD2", "EPHA7", "ERAP1", "FAM177A1", "FNTB", "GAA", "GALNT1", "GALNT2", "GALNT7", "GGH", "GLB1", "GM2A", "GNA13", "GNAI2", "GNAI3", "GNS", "GOSR1", "HEXA", "HEXB", "HPSE", "HSP90AB1", "HSP90B1", "IFNGR1", "IGF1R", "IGF2R", "IMPAD1", "IPO9", "ITGB1", "KDELR1", "KDELR3", "LAMB1", "LAMP1", "LAPTM4A", "LBR", "LETM1", "LGMN", "LIPA", "LNPEP", "LPCAT1", "M6PR", "MANBA", "METTL7A", "MFGE8", "MFN1", "MICU1", "MICU2", "MPV17", "MPV17L2", "MSMO1", "MTCH1", "MTCH2", "NAMPT", "NAP1L1", "NAP1L4", "NEU1", "NPEPPS", "NT5C3B", "NTMT1", "NUCB1", "NUCB2", "NUP37", "OPA1", "OTUB1", "OXA1L", "P3H1", "P3H4", "PAM", "PDE6D", "PEX14", "PGRMC1", "PGRMC2", "PI4K2A", "PIGK", "PLA2G15", "PLBD2", "PPT1", "PPT2", "PTPRF", "QSOX2", "RABGGTB", "RALA", "RALB", "RCN2", "RHOT2", "RPN1", "RRAGC", "RRAS2", "SCARB1", "SCARB2", "SCPEP1", "SDCBP", "SDF4", "SEC11A", "SERINC1", "SLC12A2", "SLC25A1", "SLC25A10", "SLC25A15", "SLC25A19", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC2A1", "SLC2A4", "SLC30A7", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SMPDL3A", "SMYD2", "SOAT1", "SORL1", "SORT1", "SPPL2A", "SQLE", "SRPK2", "SSR1", "STT3A", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "SURF1", "SURF4", "SV2A", "SYNGR2", "SYNJ2BP", "TAP1", "TFRC", "TGOLN2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED2", "TMED7", "TMEM165", "TNPO1", "TPBG", "TPP1", "TRAP1", "TTYH3", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "UGCG", "UNC119B", "UQCR10", "VAMP7", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ddd662d46a4f8971ba47d18342352a728e89ddee --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio", "1": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7b3371738f7dca57e535263a32dbe6bb293a8da4 --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fe73fcd0f3c9b7105b5de5e4e295e6563e9eacca83f65e721ed3a42faf5ba32a +size 216920 diff --git a/pharos_protein_category/advanced/plot_1.png b/pharos_protein_category/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..c15319dc034545d00fc96e491ac42c9be5909442 --- /dev/null +++ b/pharos_protein_category/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:509362245c428b2f600f8b78fd4666d1809abff738b472b4d8ef362e3390ea50 +size 187610 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ddd662d46a4f8971ba47d18342352a728e89ddee --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio", "1": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..08a42ce80d62d54848b3de150e4b2edd7ae53ca3 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:340b76b5c1f53fabdbcc4e98eb90895e2b056eb355a2937d929de6e7f199c5ae +size 131435 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..8b2932e1a62b77b50427bd52ea5aa0f6f33cb888 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0913de86da5f9ddb10b19695bca0fcd2f78a70b1d738e04adafa6d3f944f869b +size 135391 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..075fd07435edcfd3fd88d17776701fe2eea62181 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:82f0d800cdcaae555460e4a123b3d87920fa27851b67141b29d32a23697d2fa0 +size 76412 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c20a7707303216d4f92406ea6e348fde1091299c --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tbio 368 2349 3.136180038353982 0.0017116409252029 467.6796116504854 2434.25 -0.5416405556668178 0.3215141878443288 119.73666199244032 234.70955636597876 4.704421961664106 0.4116627836259234 0.1288988280605582 0.3956299675377899 0.5629516029603951 0.4362654082786809 0.0270824079872848 +Tclin 27 85 1.970015422114884 0.0488366030960625 19.366504854368937 86.39077669902913 0.9399778874953114 0.4805096456956057 6.659845213621253 7.009024167820235 0.9745051203556824 0.3806460486794667 0.0034247521089803 0.6557816165564712 0.0596580279202176 0.0850434910787598 0.0003969010846899 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..072ce974dd092bfa4289f06b6cef780356e2a419 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 763.0 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a269f8ed0502cf3434c722a47db54812b6f763cc --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b2b460014318dff951f398c16667c2f257dd4bbd --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tbio 0.1880774005291687 3.136180038353982 0.0017116409252029 0.0068290054627655 0.0068465637008117 2349 Q9NS69,Q8IX05,O43493,Q13501,P80303,O75629,O60499,O60637,O43169,Q96FW1,Q8IV08,Q9UMR5,Q15070,Q96D46,Q9C0H2,Q9Y287,P07602,P15260,Q13505,Q7LGA3,Q9Y282,Q99595,Q9BRR6,Q8NEW0,Q86UE4,Q15012,P24390,P02786,P43307,O00584,P98155,O95197,Q86VP1,Q68CQ7,Q9NRX5,Q14849,Q9BXS4,O43657,P50897,Q92673,Q8IZA0,Q14257,Q9NQX7,Q9NQC3,O00115,O43852,Q9P0T7,O14949,Q8TB61,Q9UHX1,P16870,Q9UBG0,Q06481,Q5SZK8,Q96G23,Q8NHP8,P30825,P11117,P55209,Q9H2C2,P17900,Q9Y2R0,Q14596,Q9H2D1,Q86UY6,Q9BSK2,Q8NBJ4,O15031,O75976,P12235,P48960,P12236,O75503,P04439,Q9NV96,P09622,Q92896,Q9UBX3,Q07954,O14773,P26368,Q13137,Q9H061,P41208,P51648,Q5KU26,P11279,O00461,P14543,O95772,Q8TCT8,Q9BQE5,Q9HC07,Q9UNN8,O75844,Q6UXD5,Q9Y680,Q16625,Q9P2W9,Q96A26,Q99733,Q08722,Q9BRK5,Q7KZN9,Q9HB40,O00592,Q99519,O15127,O15173,Q16740,P21796,Q13277,Q8WY22,Q9H9S5,Q5ZPR3,Q96P70,P54802,Q08380,O15118,P10321,P61020,Q9H4A5,Q93050,O15400,O00560,O14925,O60888,Q10472,Q8TAA9,Q9Y619,Q9UDW1,P15586,Q9BTX1,Q9H490,Q9UM22,Q13641,P10644,Q9BV86,P98164,Q13423,Q96JJ3,Q9GZM5,P16615,Q04656,Q96A57,Q92542,Q8NE01,Q9H8H3,O94813,Q14108,Q92581,Q9BT78,O96005,O43505,Q6ZRP7,Q14574,O95249,Q13190,Q9H3K2,P35613,O15260,Q9BV10,P48723,Q03518,Q9UHG3,Q15555,P43121,P15529,Q86XL3,Q4KMQ2,Q86Y82,Q8WVQ1,Q96J84,Q9Y277,O95202,Q5XKP0,P55010,P11233,Q567V2,Q8NBZ7,Q96QD8,P61916,Q9H3G5,P39210,Q9UDX5,Q70HW3,Q9BUR5,Q8N511,Q14126,P62310,P04920,Q9BTU6,P53701,Q08431,Q8IUH4,Q96J02,Q9BUN8,Q4ZIN3,Q9NR31,Q96A33,Q96PU5,Q9NRN7,P40855,Q8NCC3,Q8NHS3,Q9HDC9,Q9UG56,Q9HC21,P60900,P14672,O95831,Q13685,Q969T9,Q9UNK9,Q07065,Q9Y6B6,P20645,P07942,P33908,Q6P4A7,Q9UNK0,Q92544,Q9H0H5,P42167,O75787,P01889,Q15042,Q9BXK5,P08195,Q96KA5,Q9UPR3,Q6NUK1,Q10471,P61962,Q9HCE1,Q92973,Q96KC8,Q96JJ7,Q92643,P67812,O00264,P27544,Q6DKK2,Q96HY6,P46020,Q9NZJ7,Q9Y624,P51809,P54105,Q14739,Q9H223,Q8NBX0,Q9Y487,O43760,O94927,Q9HB90,O75955,Q7KYR7,Q6NUQ1,Q8TCT9,O76024,Q15363,P16435,O14828,O60313,O15217,Q99627,Q9H4M9,Q9NZ01,Q16527,Q9Y4P3,Q8NHH9,P13073,P36543,O14657,P61289,Q9UNS2,Q6IAA8,Q96N66,Q7Z478,A1L0T0,P05141,Q9BT22,Q9Y6M7,Q9Y6C9,Q969Q5,P62820,Q9NX40,Q9H3N1,Q2TAA5,Q15526,Q15043,P51148,P07237,Q8IXH7,Q9BZD4,O95400,Q16891,Q9NVI7,Q92572,Q6P2P2,P19022,O14681,Q13395,Q92791,P27824,Q6DD88,Q07021,Q8IUF8,A6NIH7,O95881,Q14254,Q14789,Q16637,Q8IYU8,Q9NPH0,Q01105,Q9NVH1,Q9BPX6,Q99735,Q8IZ81,Q92484,P46977,P20020,O15258,O14979,Q9H9H4,Q9BXW9,Q9P1Z2,Q9NR28,P57088,Q06136,P55795,Q15800,Q01844,Q7RTS9,Q9NPF0,Q7Z7H8,Q8IWA4,O14735,Q9HCU5,P60228,Q92692,Q9NWM8,Q9HA64,P50402,P53611,Q6NUM9,Q9UPU5,P35637,Q96C86,Q9P035,Q15293,Q15165,O75386,Q3ZCQ8,Q92733,Q9Y285,P22695,O43292,P78318,Q96AG4,P48651,Q99436,Q13561,Q92804,P07196,P57105 368 +Tclin 0.4000631267606013 1.9700154221148836 0.0488366030960625 0.1814965451713407 0.097673206192125 85 P55011,P62942,P05023,P05556,Q9Y6M9,Q9P0J0,P49721,Q99720,P06280,P42345,P08069,P0DP25,P03886,O75438,P03915,O96000,P00533,Q7L0J3,Q86Y39,O43676,P10253,O95169,P54709,P00374,P21964,P38435,Q16739 27 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cf5a05870edf46be23b058f537c007df2eda14a3 --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC2", "ASCC3", "ASF1B", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRD8", "BRD9", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C14orf2", "C16orf58", "C17orf75", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C20orf27", "C2CD5", "C5orf15", "C5orf24", "C8orf33", "CAB39", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASP2", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX4", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC25", "CCDC47", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2AP", "CD2BP2", "CD302", "CD320", "CD3EAP", "CD46", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CDV3", "CDYL", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPI", "CENPM", "CENPV", "CEP170", "CEP290", "CEP44", "CEP55", "CERK", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLIP1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT4", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPE", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT2", "CPVL", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPH2", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM213A", "FAM234B", "FAM3C", "FAM49B", "FAM50A", "FAM83D", "FAM91A1", "FAM98A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FREM2", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLM2", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INTS10", "INTS12", "INTS13", "INTS14", "INTS2", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRGQ", "IRS4", "ISCU", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "IVD", "IWS1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA2013", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIRREL1", "KLC1", "KLHDC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L3HYPDH", "LAMB1", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8E", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAP4K5", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED12", "MED16", "MED17", "MED24", "MED4", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL7A", "MFGE8", "MFN1", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRC2", "MRE11", "MRFAP1", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL58", "MRPL9", "MRPS15", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MVB12A", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NBR1", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NENF", "NES", "NEU1", "NF1", "NFATC2IP", "NFS1", "NHLRC2", "NHP2", "NID1", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PAM", "PANK4", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF14", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHPT1", "PI4K2A", "PI4KB", "PICALM", "PIGA", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIN4", "PINX1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL5", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF219", "RNF220", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAGC", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCB", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERINC1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMPDL3A", "SMS", "SMU1", "SMYD2", "SMYD3", "SMYD5", "SNAP23", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TAX1BP1", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLCD1", "TLK2", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM43", "TMEM59", "TMEM87A", "TMEM9", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TROVE2", "TRRAP", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPAN6", "TSR1", "TSR2", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TULP3", "TWF1", "TWISTNB", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", 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0000000000000000000000000000000000000000..4617e33f0abe7b3fbb5197ddc3df7ecdde62115c --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,56 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ion transport 0.6569118297027197 3.1060203116758074 0.0018962368997061 0.2716489857053312 0.1571820091528754 52 Q96QD8,P55011,O75964,P45880,P05023,P51798,Q9Y6M7,P04920,Q9C0H2,P21796,Q15043,Q8NEW0,Q93050,Q9BPX6,P20020,Q9H0H5,P16615,Q04656,Q15904,Q8NE01,Q92581,Q9H813,P54709,Q9Y487,P51790,Q4KMQ2,Q9Y277,O95202,P36543 29 +Lipid transport 0.707311142088954 2.986313630133152 0.0028236289069378 0.3763793441615992 0.1571820091528754 24 O15118,P61916,P98155,Q9NV96,Q9BUR5,P04114,Q14849,Q4KMQ2,Q9H2C2,P01130,Q9BQE5 11 +Antiport 0.8712047899665506 2.79791622017404 0.0051433451769216 0.5773264540895208 0.1717877289091817 9 P12235,P12236,P51798,P51790,P04920,Q92581,O95202 7 +Sphingolipid metabolism 0.817338184285016 2.6956583866318646 0.0070249670999562 0.6918934595405343 0.1955282509487825 10 P04062,O95470,P07602,O15269,Q16739,P17900,Q9NZ01,Q13510 8 +Endocytosis 0.6164165686058041 2.5020894353692955 0.0123462731799512 0.8744010401089172 0.2945468030074095 38 P02786,Q9UBG0,P98155,Q99523,Q07954,Q92673,P01130,P05067 8 +Phospholipid metabolism 0.7299873470217492 2.389083674726875 0.0168904550100852 0.941854057121582 0.3082368797139737 12 Q8NF37,Q96N66,Q9UG56,Q9NRX5,Q9NPH0,O14735,P48651,P35790 8 +Phospholipid biosynthesis 0.7246535616352946 2.2946594196769916 0.0217526501219786 0.9745943934450928 0.3082368797139737 11 Q8NF37,Q96N66,Q9UG56,Q9NRX5,P48651,O14735,P35790 7 +Sodium transport 0.8441089596324284 2.2825031869169456 0.0224596495449245 0.9774838704795002 0.3082368797139737 6 Q96QD8,P55011,P05023,Q9Y6M7,Q92581 5 +Adaptive immunity 0.6550476664009695 2.205370856367865 0.0274280813841787 0.9903854663608628 0.3082368797139737 15 P01889,P10321,P04439,Q03518,Q96FW1,Q9NZ08 6 +Calcium transport 0.8214761850621448 2.1818134041029977 0.0291233069047469 0.9928154327849296 0.3082368797139737 6 Q9BPX6,P16615,O95202 3 +Sterol metabolism 0.5738506835736112 2.092801869904188 0.0363668448359149 0.9979428801506124 0.3082368797139737 24 Q15392,P04062,Q14739,O15118,P61916,P98155,P00387,Q15800,Q16850,P35610,P04114,Q9H2C2,P01130 13 +Cholesterol metabolism 0.5738506835736112 2.092801869904188 0.0363668448359149 0.9979428801506124 0.3082368797139737 24 Q15392,P04062,Q14739,O15118,P61916,P98155,P00387,Q15800,Q16850,P35610,P04114,Q9H2C2,P01130 13 +Amino-acid transport 0.7584285125923301 1.9974175882231016 0.0457798387574921 0.9996006862655727 0.3082368797139737 7 Q96QD8,Q15758,P08195,P30825,Q6P4A7 5 +ER-Golgi transport 0.5248261044832506 1.9222258409881168 0.0545773466275976 0.9999149757689906 0.3082368797139737 47 O43731,Q9P2W9,P51572,P62820,P54920,Q9Y282,Q9NR31,P35606,P24390,O95197,O95070,Q9Y6B6,P49257,Q969X5,P61019,Q9HCU5,Q9Y678,P49755,O95249,Q6NUQ1,Q15363,P18085 22 +Steroid metabolism 0.5442369648692612 1.8836421621024375 0.0596133947361452 0.999965152264964 0.3082368797139737 26 Q15392,P04062,Q14739,O15118,P61916,P98155,P00387,Q15800,P14324,Q16850,P35610,P04114,Q9H2C2,P01130 14 +Sugar transport 0.8588843592761052 1.8483261146081056 0.0645551800933605 0.9999855444332372 0.3082368797139737 4 P11166,P31751 2 +Cell adhesion 0.5254877798876582 1.8275742837632496 0.0676134682240188 0.9999916337547794 0.3082368797139737 40 P05556,Q08722,Q14126,O00592,Q08431,P05067,Q08380,P19022,Q14254,P07942,P06756,Q5SZK8,Q92692,Q14574,Q9Y251,P48960,P10586,P43121,P14543 19 +Respiratory chain 0.533985397414899 1.823223136160728 0.0682696023102618 0.999992561691555 0.3082368797139737 31 O14949,O96000,Q9Y6M9,P00403,Q9P0J0,Q86Y39,P22695,Q9UDW1,O43676,Q6DKK2,P03886,O75438,O95169,P03915 14 +Apoptosis 0.4199782711747368 1.795929028416437 0.0725058050724127 0.9999965248751128 0.3083717860664588 125 P61289,Q13501,P09601,Q9UDX5,Q96A26,O95470,Q9P0J0,P21796,Q96J02,P05067,Q15375,O14681,O95197,Q07021,Q86VP1,O95831,O00115,Q9UHX1,Q96JJ3,Q9BXK5,Q96KA5,Q6NUQ4,Q9NZJ7,Q9H3K2,P12236,O60313,P31751 27 +Immunity 0.4171806578385527 1.6929402767669324 0.0904668358151956 0.9999998673534176 0.3433627632076744 74 Q13501,P10321,Q96J02,O00584,P04439,Q03518,Q96FW1,Q8IV08,P15529,Q9NZ08,Q9NUD5 11 +Symport 0.6714130422977892 1.5791298843909998 0.1143062683140669 0.999999998428348 0.3895744246622283 7 Q96QD8,P55011,Q9Y6M7 3 +Neurotransmitter transport 0.9498525073746336 1.544297397370894 0.1225163027979419 0.9999999996681648 0.409204451345126 2 Q7L0J3 1 +Angiogenesis 0.5485661355466268 1.373698582356899 0.1695352771941731 0.9999999999999664 0.4815240424540087 12 Q13685,P35613,Q08431 3 +Potassium transport 0.843278688524587 1.359996189312617 0.1738311297877195 0.999999999999986 0.4815240424540087 3 P05023,P55011 2 +Autophagy 0.4730708546922459 1.3504633165429418 0.1768674128510159 0.9999999999999925 0.4815240424540087 29 Q13501,O14681,Q9Y4P8,Q9Y6I9,Q14964,Q969Q5,P62820,Q9BXS4,Q13137,P51149 10 +Translocation 0.4558907048369408 1.301568070162896 0.1930640808462418 0.9999999999999998 0.4885106288079149 45 Q9NS69,O60830,O14925,P41208,Q9BTX1,Q99595 6 +Zinc transport 0.8666011143887418 1.2004142039708166 0.2299785151499094 1.0 0.5227494440664737 2 Q8NEW0 1 +Electron transport 0.442521965928317 1.184394218333929 0.2362570478182926 1.0 0.5227494440664737 45 O14949,O43169,O96000,Q9Y6M9,P00403,Q9P0J0,Q9H1E5,Q86Y39,Q6DKK2,Q9UDW1,Q9H3N1,O43676,P22695,P03886,O75438,O95169,P03915 17 +Sensory transduction 0.6526499993368619 1.1787369475412823 0.2385029384175432 1.0 0.5227494440664737 5 P50897,O60313,Q9H6K4 3 +Vision 0.6526499993368619 1.1787369475412823 0.2385029384175432 1.0 0.5227494440664737 5 P50897,O60313,Q9H6K4 3 +Complement pathway 0.8603736479842745 1.1749168944073722 0.2400279658712949 1.0 0.5227494440664737 2 P15529 1 +Protein transport 0.4398691997892269 1.1651455285914716 0.2439600903140126 1.0 0.5227494440664737 231 O43731,P20339,Q9NS69,Q8N4H5,O96008,O60499,O60830,Q96L92,Q96D46,Q99442,Q13505,O60831,Q99595,P51151,P24390,Q9H0U4,Q9UID3,Q8TEX9,Q9P0T7,O15126,P61019,P49755,O75381,P49321,Q8WUM4,O60826,Q12907,P41208,Q96CW1,O43633,Q9UPT5,Q92621,Q9P2W9,P51572,Q15036,O15127,P54920,Q9NP72,Q96P70,Q8N1F7,P61020,O00186,O14925,Q15388,Q9HD20,P49257,Q9BTX1,Q12769,Q9Y4P1,P55060,Q9HD26,Q9Y3E0,Q15629,Q9Y678,Q10567,O95249,Q03518,Q9Y5J9,Q86Y82,Q96AX1,P18085,Q15286,Q9H089,Q9Y3E7,O75431,P50542,Q9NVU7,Q9C0E2,Q9BUN8,Q9NR31,P35606,O75396,O95070,Q9Y6B6,Q9Y3B3,Q92973,P51809,Q8NFH4,Q6NUQ1,Q15363,O14828,Q9H4M9,Q969Q5,P62820,A0AVF1,P51148,Q92572,A6NIH7,Q969E2,Q9H9H4,Q14964,Q9HCU5,Q3ZCQ8,P51149 94 +GPI-anchor biosynthesis 0.6019562730648029 1.1493325154251055 0.250418895361185 1.0 0.5227494440664737 6 Q9H490,Q92643 2 +Sodium/potassium transport 0.8430022943297277 1.1041081252920664 0.2695462370353572 1.0 0.5363032125133157 2 P05023 1 +Phagocytosis 0.7733077952882035 1.0817453811396127 0.2793656822209569 1.0 0.5363032125133157 3 Q96JJ3 1 +Transport 0.4924917358873266 1.0721377451714815 0.2836581675346048 1.0 0.5363032125133157 471 O43731,Q9NS69,P20339,Q8N4H5,O96008,O60499,O60830,O43169,Q96L92,Q96CU9,Q96D46,Q9C0H2,Q99442,Q13505,Q9Y282,Q99595,O60831,Q8NEW0,P51151,O43808,Q15012,P24390,P98155,O95197,Q9H0U4,Q14849,Q92673,Q9UID3,Q8TEX9,Q9P0T7,O14949,Q8TB61,O15126,O14678,Q99523,P30825,Q7L0J3,Q9H1E5,Q86Y39,P61019,O43676,P56134,Q9H2C2,Q9H813,Q9H2D1,Q9BSK2,P61421,P49755,O75381,P49321,P12235,Q15758,P12236,Q8WUM4,Q9NV96,Q9UBX3,O60826,P11717,Q12907,P41208,O00461,Q96CW1,Q9BQE5,O43633,Q5T8D3,Q9UPT5,Q9H9B4,P45880,Q9P2W9,Q92621,P04114,O15127,P21796,Q13277,Q96P70,O15118,P61020,Q93050,O14925,Q9Y619,Q9UDW1,Q9HD20,Q9BTX1,P01130,O75438,P98164,P16615,Q04656,Q15904,Q8NE01,Q92581,Q15629,O95249,Q13190,Q03518,P51790,P11166,Q4KMQ2,Q86Y82,Q9Y277,O95202,P31751,Q96QD8,P61916,O75964,Q70HW3,Q8N4V1,Q9BUR5,P51798,Q9Y6M9,P04920,Q9BUN8,Q9NR31,Q8NHS3,Q99720,Q9HC21,P14672,O95070,Q9Y6B6,P20645,P03886,Q6P4A7,Q9UNK0,Q9H0H5,P08195,Q9Y3B3,Q6NUK1,Q92973,P23786,Q6DKK2,Q9NZJ7,P51809,Q9Y487,Q8NFH4,Q6NUQ1,Q15363,O14828,Q9H4M9,P36543,P55011,P05023,P05141,Q9Y6M7,Q9Y6C9,Q9P0J0,Q969Q5,P62820,Q9H3N1,Q15043,A0AVF1,P51148,Q92572,A6NIH7,Q969E2,Q9BPX6,P20020,P03915,Q9H9H4,O96000,P00403,Q14964,Q9HCU5,O95169,P54709,Q3ZCQ8,Q8IXU6,P22695,P51149,O00400 169 +Notch signaling pathway 0.5737057196012557 1.0116434172977615 0.3117085786540263 1.0 0.5511874153464986 6 P05067 1 +Hydrogen ion transport 0.4346601513382969 1.0078015799050803 0.3135497272929184 1.0 0.5511874153464986 18 O75964,Q9Y487,Q93050,Q15904,P56134,P36543 6 +Leukotriene biosynthesis 0.8056374959029813 0.953920586944996 0.3401238417496401 1.0 0.5795987915529582 2 Q99735 1 +Exocytosis 0.4708931298158847 0.9110243605399828 0.3622825383388119 1.0 0.5994132463031304 12 P11233,Q9BRK5 2 +Aromatic hydrocarbons catabolism 0.7374631268436541 0.6921395845577879 0.4888496748441824 1.0 0.7172295155922301 2 P34913 1 +Detoxification 0.7374631268436541 0.6921395845577879 0.4888496748441824 1.0 0.7172295155922301 2 P34913 1 +Unfolded protein response 0.4565912850812052 0.5119950645020115 0.6086544637687026 1.0 0.8200810998211678 7 Q15629 1 +Neurogenesis 0.3651895796723978 0.4877178729910787 0.6257496902209558 1.0 0.8293666529119018 42 Q15375,P98164,Q9NQC3,Q12834,Q16637,O94813,P55209,O14786 8 +Polyamine biosynthesis 0.6430678466076627 0.3779742632553918 0.7054497131406179 1.0 0.8993137564464366 2 P52788 1 +Fertilization 0.5733354487652422 0.3616270118294351 0.7176307764042824 1.0 0.907911664087236 3 P15529 1 +Prostaglandin biosynthesis 0.5988200589970449 0.2608113547464513 0.794237987608496 1.0 0.9297849790329272 2 Q9H7Z7 1 +Lipid degradation 0.3484397459354675 0.2293542015479214 0.8185936292696676 1.0 0.9427940419864448 13 Q99519,Q8NHP8,Q8NCC3 3 +Glycogen metabolism 0.3710961835410067 0.1877417442349116 0.8510791049056663 1.0 0.9668721804030358 8 P31751 1 +Lipid biosynthesis 0.3238812484810685 0.1532768027091579 0.878179993254266 1.0 0.9724768218355188 47 Q15392,Q8NF37,Q14739,Q96N66,Q9P035,P00387,Q9UG56,Q15800,Q16850,Q96G23,Q9NRX5,P48651,Q53GQ0,O14735,Q16739,P35790,Q9NZ01,P27544 18 +Sterol biosynthesis 0.3361671700680082 0.1518498164933672 0.8793053898033734 1.0 0.9724768218355188 12 Q15392,Q14739,P00387,Q15800,Q16850 5 +Cholesterol biosynthesis 0.3361671700680082 0.1518498164933672 0.8793053898033734 1.0 0.9724768218355188 12 Q15392,Q14739,P00387,Q15800,Q16850 5 +Differentiation 0.2616618534382705 0.1042049748738458 0.9170066860900596 1.0 0.988936720100585 83 Q9H0H5,O94901,Q13501,Q9P273,Q9GZM5,Q9Y2W6,Q07820,Q99523,Q12834,Q16352,O94813,Q13685,O96005,Q16527,O14786,Q96TC7,Q96PU5 17 +Oogenesis 0.4129793510324416 0.0307268194746257 0.9754874024094692 1.0 1.0 2 Q9H6S0 1 +Hypusine biosynthesis 0.3998688954441038 0.0269772755528803 0.978477858915776 1.0 1.0 2 Q9BU89 1 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e776994d4bc31fe7c141132a1f6e5d101f0b9950 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Anion exchange", "Antiport", "Antiviral defense", "Apoptosis", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Bile acid catabolism", "Biological rhythms", "Biomineralization", "Blood coagulation", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Copper transport", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Hemostasis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubl conjugation pathway", "Unfolded protein response", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABCE1", "ABCF3", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACAT1", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOX1", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN4", "ACTR3", "ADAR", "ADGRE5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDOA", "ALDOC", "ALKBH5", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEX1", "API5", "APOB", "APOBEC3C", "APOL2", "APOO", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL8B", "ARMT1", "ARV1", "ASAH1", "ASCC2", "ASCC3", "ASF1B", "ASH2L", "ASNA1", "ASNS", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATIC", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "AUP1", "AURKA", "BABAM1", "BAG3", "BAG6", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BIRC6", "BMS1", "BOP1", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRD8", "BRD9", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C2CD5", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CAMK2G", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CASP2", "CASP3", "CBL", "CBX3", "CBX4", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CD2AP", "CD2BP2", "CD3EAP", "CD46", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDS2", "CDYL", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP290", "CEP55", "CERS1", "CERS2", "CETN2", "CFL1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLINT1", "CLIP1", "CLPTM1", "CLPTM1L", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNOT1", "CNOT4", "CNOT9", "COG7", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPZ1", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT2", "CREG1", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CXADR", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCP2", "DCPS", "DCTN1", "DCTN3", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJB1", "DNAJC13", "DNAJC2", "DNAJC3", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPY30", "DPYSL2", "DSC1", "DSC2", "DSC3", "DSG2", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMG1", "EML4", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN2", "ERO1A", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FAM50A", "FAM83D", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXC1", "FOXRED1", "FREM2", "FRG1", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCC2", "GCFC2", "GCN1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GHITM", "GINS1", "GINS2", "GINS3", "GINS4", "GLRX", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLIM4", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPHN", "GPI", "GPKOW", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSS", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTPBP10", "GTPBP4", "GYS1", "H2AFX", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRA", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HPSE", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILVBL", "IMPDH1", "IMPDH2", "INA", "INCENP", "INTS13", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BP1", "IST1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD5", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIF11", "KIF18B", "KIF1B", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIFBP", "KIFC1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "LAMB1", "LAMC1", "LAMP1", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDLR", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LRP1", "LRP2", "LRPPRC", "LRRC8E", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LZTS2", "M6PR", "MACF1", "MAD2L1", "MAGT1", "MAP1S", "MAP2K4", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MEAF6", "MECP2", "MECR", "MED1", "MED12", "MED16", "MED17", "MED24", "MED4", "MESD", "METTL1", "MFGE8", "MFSD3", "MFSD5", "MFSD8", "MGEA5", "MGST2", "MIA3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MMGT1", "MMS19", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MRC2", "MRE11", "MRI1", "MRPL58", "MRPS27", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MVB12A", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCK1", "NCKAP1", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEK9", "NELFCD", "NELFE", "NES", "NEU1", "NFS1", "NHP2", "NID1", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NMD3", "NME1", "NME2", "NME3", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP10", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NTHL1", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD7B", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PANK4", "PARG", "PARK7", "PARN", "PARP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCLAF", "PCM1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PI4KB", "PICALM", "PIGA", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMS1", "PMVK", "PNN", "PNP", "PNPT1", "PODXL", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POP1", "PPAT", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1R8", "PPP2R1A", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAG1", "PRKCD", "PRKDC", "PRKRA", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTK2", "PTK7", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PWP1", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABEP1", "RABGAP1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP2", "RANBP3", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBM10", "RBM14", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCOR1", "RECQL5", "REEP4", "REL", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN3", "RNASET2", "RNF14", "RNF2", "RNF219", "RNF220", "RNF40", "RNMT", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDF4", "SDHA", "SDHB", "SEC16A", "SEC22B", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SEPT9", "SERINC1", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD2", "SNAP23", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SON", "SORL1", "SORT1", "SPATA5", "SPC24", "SPC25", "SPECC1L", "SPEN", "SPOUT1", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SRFBP1", "SRM", "SRPK1", "SRPK2", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STK26", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "TACC3", "TACO1", "TAF6", "TAF6L", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TAX1BP1", "TBCB", "TBK1", "TBL1XR1", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TDP2", "TDRKH", "TECR", "TENM3", "TERF2IP", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TK1", "TLK2", "TLN1", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM14C", "TMEM206", "TMEM214", "TMEM30A", "TMEM59", "TMEM9", "TMX1", "TMX4", "TNPO1", "TNPO3", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TP53", "TP53BP1", "TPI1", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TROVE2", "TRRAP", "TSC2", "TSFM", "TSG101", "TSNAX", "TSR1", "TSR2", "TTC19", "TTC26", "TTC4", "TTLL12", "TTYH3", "TUBB2B", "TUFM", "TWISTNB", "TXLNA", "TXLNG", "TXNL1", "TXNRD1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VLDLR", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "WAPL", "WARS", "WBP11", "WDR12", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR5", "WDR6", "WDR61", "WDR75", "WIPI2", "XAB2", "XPC", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YIPF3", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "ZC3H11A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZMYM2", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF638", "ZNF687", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAMP", "ABCD4", "ACBD5", "ACP6", "ADGRE5", "AIFM1", "AKT2", "ANO6", "AP1B1", "AP2M1", "AP3S1", "APOB", "APOL2", "APOO", "APP", "ARF4", "ARV1", "ASAH1", "ATG4B", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5J2", "ATP5L", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1E1", "ATP7A", "BCAP31", "BCL2L13", "BSG", "C1QBP", "CALCOCO2", "CCDC22", "CD46", "CD47", "CDC20", "CDH2", "CDIPT", "CERS1", "CERS2", "CETN2", "CHKA", "CHMP2A", "CHMP3", "CLCN3", "CLCN7", "CLPTM1", "CLPTM1L", "CNNM3", "COPB2", "COPG1", "COX2", "CPT2", "CSE1L", "CSRP2", "CYB5B", "CYB5R3", "CYP51A1", "DERL1", "DHCR24", "DNASE2", "DOHH", "DSC3", "DSG2", "EHD1", "EI24", "ELMO2", "EPHA7", "EPHX2", "ERAP1", "ERGIC1", "ERGIC3", "EXOC7", "FAM162A", "FDPS", "FLOT2", "FOXRED1", "FREM2", "GBA", "GHITM", "GM2A", "GOLIM4", "GOLT1B", "GOPC", "GOSR1", "HACD3", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HPSE", "HSD17B12", "IGF2R", "INA", "IPO4", "IPO9", "ITCH", "ITGAV", "ITGB1", "KDELR1", "KDELR3", "LAMB1", "LAPTM4A", "LBR", "LDLR", "LETM1", "LGALS3BP", "LMAN1", "LMAN2", "LPCAT1", "LRP1", "LRP2", "LSG1", "M6PR", "MBOAT7", "MCAM", "MCL1", "MFGE8", "MFSD8", "MGST2", "MICU1", "MMGT1", "MRC2", "MSMO1", "MTCH1", "MTCH2", "MTFP1", "MTX1", "MTX2", "NAP1L1", "NAPA", "NASP", "ND1", "ND5", "NDC1", "NDUFA11", "NDUFA13", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB8", "NDUFB9", "NECTIN2", "NEDD4L", "NEU1", "NID1", "NMD3", "NPC1", "NPC2", "NRP1", "NUP160", "NUP205", "NUP37", "NUP93", "OPA1", "OPA3", "OTUB1", "PDCD6IP", "PEX14", "PEX5", "PIGK", "PIGU", "PISD", "PLA2G15", "PLBD2", "PLD3", "PODXL", "PPT1", "PRAF2", "PREB", "PSAP", "PSME3", "PTDSS1", "PTGES2", "PTPRF", "PUF60", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RACGAP1", "RALA", "RINT1", "RMDN3", "RNASET2", "RTN3", "RTN4", "SAR1A", "SAR1B", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SDAD1", "SDF4", "SEC22B", "SEC62", "SERINC1", "SFXN1", "SFXN4", "SGPL1", "SIGMAR1", "SLC12A2", "SLC1A5", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SLIT2", "SMN1*", "SMS", "SNX17", "SNX27", "SOAT1", "SORL1", "SORT1", "SPTLC1", "SQSTM1", "STARD3", "STX10", "STX12", "STX18", "STX3", "STX5", "STX8", "STXBP3", "SUN1", "SV2A", "TAP1", "TAX1BP1", "TDRKH", "TECR", "TENM3", "TEX264", "TFRC", "TIMM17A", "TIMM17B", "TIMM23", "TIMM50", "TIMM8B", "TMED10", "TMED2", "TMED7", "TMEM206", "TMEM214", "TMEM30A", "TMEM59", "TMEM9", "TMX1", "TMX4", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TRAM1", "TTC19", "TTC26", "TTYH3", "UGCG", "UNC119B", "UQCR10", "UQCRC2", "UQCRQ", "VAMP7", "VDAC1", "VDAC2", "VDAC3", "VLDLR", "VPS33A", "VPS37B", "VPS51", "WIPI2", "XPO4", "YIF1A", "YIPF3", "YTHDC2", "ZCCHC3"]} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/idx2term.json b/protein_atlas_disease_involvement/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/basic/idx2term.json b/protein_atlas_disease_involvement/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..4fc8b7537a048c235a13e829930e86c994d4ccf2 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Congenital disorder of glycosylation", "1": "Primary mitochondrial 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0000000000000000000000000000000000000000..76ddd8d111875fe2ef2443db526918f9c4c8a935 --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Gangliosidosis 4 5 2.3995361862334788 0.016415857197829 2.8567961165048543 4.902912621359223 0.2158556094961241 0.1574800557957235 1.2213224676890235 0.2960767122713962 1.9039254823866087 0.2239345049259472 1.0653029481854897e-07 0.0238038053541035 3.9836639152197847e-08 8.018093555049281e-09 2.6454681464607386e-07 +Mucopolysaccharidosis 3 5 2.1737601248579983 0.0297231546185543 2.254854368932039 4.752427184466019 0.4843930061917075 0.2034155563537636 0.9831595235232706 0.7286567852681505 1.626107445717624 0.2463507210616131 0.0006977887477165 1.0 0.1008375048293403 9.701143498590324e-05 0.0013781701696679 +Amyloidosis 3 6 1.9629157816088072 0.0496559606937196 1.087378640776699 3.703883495145631 0.4647215876526214 0.3864606223560753 0.9068969404042873 1.1014925734380785 1.1974619704686245 0.3115672738393393 0.0025369657709893 0.0022827689145391 0.0003602808960722 0.0051503840765812 0.0048822579474643 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..41bceff49f4dd6398c5070d5a8c42f6489942760 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 117, + "title": "Average number of proteins per term", + "value": 20.94017094017094 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..82264cd042c469be911e7ce1f80f538a6f59c922 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a28fae3005310a1844020c3f6ec75266d2337627 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,44 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Gangliosidosis 0.9333989501312282 2.3995361862334788 0.016415857197829 0.8558058426091893 0.5741811438029744 5 P16278,P06865,P17900,P07602 4 +Mucopolysaccharidosis 0.8790241508249612 2.1737601248579983 0.0297231546185543 0.970705027061058 0.5741811438029744 5 P54802,P16278,P15586 3 +Neuronal ceroid lipofuscinosis 0.9039029189898262 2.030542363855821 0.0423014395316252 0.9936353628239478 0.5741811438029744 4 O75503,O14773,P50897 3 +Amyloidosis 0.7731558260941838 1.9629157816088072 0.0496559606937196 0.9974173827521972 0.5741811438029744 6 Q9Y287,P05067,Q92673 3 +Alzheimer disease 0.7224022315759855 1.7273697542713455 0.0841012789848587 0.9999656321828276 0.5741811438029744 6 P05067,Q92673 2 +Spinocerebellar ataxia 0.6485401145695164 1.7062174140371815 0.0879676076586462 0.9999790491906436 0.5741811438029744 9 Q8IV08 1 +Congenital disorder of glycosylation 0.5174109566493825 1.697491057477008 0.0896038603447901 0.9999830192182624 0.5741811438029744 19 Q9HC07,O75787,Q9BV10,Q9BT22,Q8N511,Q10471,Q15904,Q2TAA5 8 +Lissencephaly 0.6116161222481457 1.6372298573783002 0.1015824506498941 0.999996394607743 0.5741811438029744 10 P07942,O43505,Q9H9S5 3 +Diabetes mellitus 0.5977667534427158 1.6074044015940208 0.1079656851595336 0.9999984345375432 0.5741811438029744 11 P03886,P14672,P31751 3 +Primary mitochondrial disease 0.3807545465549278 1.5628204571624054 0.1180948310483598 0.9999995885084672 0.5970260253519035 80 P39210,Q70HW3,Q7KZN9,Q9Y6M9,Q9P0J0,Q15526,Q07021,O95831,P03886,Q6P4A7,P03915,O14949,P00403,Q86Y39,O43676,Q9Y2R0,Q6DKK2,O95169,P12235,Q9UBX3,O60313,Q5XKP0,P13073 23 +Dystroglycanopathy 0.7721380368013993 1.489473595069963 0.1363627014814823 0.9999999644554796 0.5970260253519035 4 Q9H9S5 1 +Niemann-Pick disease 0.9151098000655522 1.400376668216513 0.161400553050538 0.9999999988626742 0.5970260253519035 2 O15118 1 +Gaucher disease 0.9056047197640238 1.361059957777317 0.1734947424099548 0.999999999792156 0.5970260253519035 2 P07602 1 +Amyotrophic lateral sclerosis 0.5147151474601025 1.3381968671252598 0.1808322701173268 0.9999999999267812 0.6044964458207783 15 Q99720,Q13501 2 +Parkinsonism 0.5263470866965891 1.2423130194185843 0.2141210935815012 0.999999999999429 0.6760550326168044 12 Q15043,P04062,Q96A57,O75787 4 +Neurodegeneration 0.3778269637991835 1.2132434196248922 0.225036768062983 0.9999999999998888 0.6760550326168044 128 Q13501,P39210,P05023,Q8IV08,Q9Y287,Q15526,Q15043,P05067,P54802,P04062,P56192,Q8NHS3,Q99720,O95831,Q16637,P50897,Q92673,P03886,Q13510,O75787,P06865,Q04656,Q96A57,P07686,Q14108,P27544,P35637,O75503,O14773,O60313,O15269,P07196,P51149 33 +Leber hereditary optic neuropathy 0.8538184201901009 1.1481384328249766 0.2509114205196487 0.999999999999998 0.6760550326168044 2 P03886 1 +MELAS syndrome 0.8538184201901009 1.1481384328249766 0.2509114205196487 0.999999999999998 0.6760550326168044 2 P03886 1 +Craniosynostosis 0.789269872395147 1.144925897709561 0.2522398549922409 0.9999999999999984 0.6760550326168044 3 P16435 1 +Ichthyosis 0.5832368791679339 1.140104137852471 0.2542429182490546 0.9999999999999988 0.6760550326168044 7 P04062,P51648,P18074 3 +Congenital muscular dystrophy 0.6393290692070042 1.1184497409595835 0.2633749604127322 0.9999999999999996 0.6826817904592528 5 Q9H9S5 1 +FDA approved drug targets 0.3609695503476757 1.1003739279368652 0.2711692333683728 1.0 0.6826817904592528 117 Q9UNN8,Q96QD8,P55011,P62942,P05023,P05556,P05141,P15260,P05067,Q14534,P02786,P49721,Q99720,Q16850,P42345,P35610,Q16637,P20645,P03886,P20020,P49356,P06756,Q13423,P16615,P00533,Q7L0J3,P23786,P10253,P00374,P12235,P21964,P12236,P38435,Q16739 34 +Peroxisome biogenesis disorder 0.7426229508196693 0.9612855056242277 0.3364086337305103 1.0 0.7394313968236312 3 O75381,P40855 2 +Zellweger syndrome 0.7426229508196693 0.9612855056242277 0.3364086337305103 1.0 0.7394313968236312 3 O75381,P40855 2 +Microphthalmia 0.5030808285549593 0.8269077655836338 0.408289341571864 1.0 0.8096585248120016 8 P53701 1 +Dystonia 0.4995622580723782 0.8085863989372484 0.4187530907408028 1.0 0.8165685269445655 8 Q15043,O75569,P04350,P11166 4 +Ehlers-Danlos syndrome 0.679999999999997 0.7225262047670662 0.469971020234567 1.0 0.8651394681498548 3 Q9NWM8,Q96L58 2 +Primary microcephaly 0.4991367636180879 0.7183727365897404 0.4725274924630014 1.0 0.8651394681498548 7 Q86XL3 1 +Cushing syndrome 0.6764241126670036 0.7093100107833248 0.4781321174759476 1.0 0.8651394681498548 3 P10644 1 +Oncogene 0.6721122828539559 0.6934496831419701 0.4880273922896616 1.0 0.8651394681498548 3 Q92520 1 +Parkinson disease 0.4506905689085348 0.558070302066113 0.5767963790238646 1.0 0.9780460339969878 8 Q96A57 1 +Leigh syndrome 0.3902652079559578 0.4166909646389349 0.6769044640577282 1.0 1.0 11 Q15526,Q7KZN9 2 +Holoprosencephaly 0.6463454605047554 0.3875380119289582 0.6983579496771462 1.0 1.0 2 Q8N3U4 1 +Rhizomelic chondrodysplasia punctata 0.5544262295082014 0.3073925559349873 0.758544593599404 1.0 1.0 3 O00116,P50542 2 +Cataract 0.3302550345685874 0.261193860348329 0.7939430125634515 1.0 1.0 26 Q8TC12,Q9UG56,Q15800,O00400,O76024,P11166,Q9H6K4,Q53H12,P08670,P18074 10 +Cardiomyopathy 0.3237664226592611 0.2590643097598509 0.7955856216216746 1.0 1.0 21 P19022,P12235,Q14126,O60313,Q9H9S5,Q53H12,P50402 7 +Xeroderma pigmentosum 0.459804704324786 0.2585038814436678 0.7960180537445747 1.0 1.0 4 Q92889,P18074 2 +Cockayne syndrome 0.5143813407835613 0.2056864759391005 0.8370358233219135 1.0 1.0 3 Q92889 1 +Albinism 0.5118032786885327 0.1998012249993348 0.8416360432344581 1.0 1.0 3 Q86YV9,O00203 2 +Hermansky-Pudlak syndrome 0.5118032786885327 0.1998012249993348 0.8416360432344581 1.0 1.0 3 Q86YV9,O00203 2 +Elliptocytosis 0.500819403474265 0.0899608453103438 0.928318329536964 1.0 1.0 2 O60488 1 +Charcot-Marie-Tooth disease 0.3016137289356862 0.0773347185562661 0.938357272184264 1.0 1.0 25 P54802,P56192,P39210,P05023,O95831,Q15526,P07196 7 +Intrahepatic cholestasis 0.4749262536873093 0.0648778890063836 0.9482712255137348 1.0 1.0 2 Q9UJS0 1 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..916e600b96726da5085107ca53f0b34fb7f5103b --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atherosclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Brugada syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hemolytic uremic syndrome", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Peters anomaly", "Phenylketonuria", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Senior-Loken syndrome", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABCB1", "ABCB7", "ABCD4", "ABHD12", "ABI1", "ACAA1", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACVR1B", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AKAP12", "AKAP13", "AKR1B1", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANO10", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA7", "AP1B1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APEX1", "APOB", "APOL2", "APP", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL2", "ARL3", "ARPC1B", "ARV1", "ASAH1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATIC", "ATL3", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5A1", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP7A", "ATXN10", "AURKA", "B3GALT6", "B4GAT1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCL10", "BCLAF1", "BCOR", "BCS1L", "BIRC6", "BLMH", "BLVRB", "BMS1", "BRAT1", "BRCA1", "BRD4", "BRD7", "BRI3BP", "BUB1B", "C19orf70", "C1QBP", "CAD", "CALM3", "CALR", "CAMK2G", "CANT1", "CANX", "CAP2", "CAPN1", "CAPN5", "CARM1", "CARS", "CASP2", "CASP3", "CAST", "CBFB", "CBL", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCT5", "CD320", "CD46", "CDC20", "CDC27", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDKAL1", "CEP290", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHMP1A", "CHMP2B", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLIP1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNOT1", "COA3", "COA7", "COG7", "COLGALT1", "COMT", "COPA", "COPB2", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT2", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DBN1", "DBT", "DCPS", "DCTN1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIS3", "DKC1", "DLD", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJB1", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DSC2", "DSC3", "DSG2", "DSP", "DYM", "DYNC1H1", "DYNC1I2", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGFR", "EHMT1", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENO2", "EPB41", "EPB41L3", "EPHA7", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOSC2", "EXOSC3", "EXOSC9", "EZR", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FAM3C", "FAM50A", "FAM83D", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FDPS", "FDXR", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FNTB", "FOXC1", "FOXRED1", "FREM2", "FSCN1", "FTO", "FTSJ1", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GATB", "GATC", "GBA", "GCDH", "GDAP1", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GINS1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPHN", "GPI", "GRB2", "GSK3A", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2I", "GUSB", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIP1", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2R", "IKBKB", "ILF3", "ILK", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INTS12", "IPO7", "IRS4", "ITGAV", "ITGB1", "ITM2B", "ITPA", "IVD", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIF11", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KMT2A", "KTN1", "LAMB1", "LAMC1", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LGMN", "LIPA", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRP1", "LRP2", "LRPPRC", "LSS", "LTA4H", "LYN", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK3", "MARS", "MASTL", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MECR", "MED1", "MED12", "MED17", "MESD", "MFGE8", "MFSD8", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MOGS", "MORC2", "MPI", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MYH10", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NAGLU", "NAMPT", "NANS", "NAXE", "NBN", "NCAPD2", "NCAPH", "NCSTN", "ND1", "ND5", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB3", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NEU1", "NF1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NME2", "NNT", "NONO", "NOP10", "NOP56", "NPC1", "NPC2", "NPM1", "NRP1", "NSD1", "NSD2", "NSDHL", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NTHL1", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", 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"PRDX4", "PRDX5", "PREPL", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PSPH", "PTDSS1", "PTK2", "PTPN11", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "RAB10", "RAB18", "RAB3GAP2", "RAB7A", "RABEP1", "RABL3", "RAC1", "RAD21", "RAD23B", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM28", "RBMX", "RDH11", "RDX", "REL", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RIPK1", "RNASEH2A", "RNASET2", "ROCK2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS28", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRAGC", "RRAS2", "RRM1", "RRM2", "SAMHD1", "SAR1B", "SARS", "SART1", 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sha256:5aa55a38492bbf563867621145174c39c2a38f7c5b4215cea7d4bc33907742a9 +size 142627 diff --git a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..25e9961850b0139408eee8321c4b74affb2b45fd --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e17c85d495cd6ba511c30b60f8263be3dec1bb0f6aecbd1a56c1f0453355f5b4 +size 78128 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5dd3d03c9fc613482285dc286fe9c1c8e5273b0a --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,9 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Receptor 37 54 4.322841301137454 1.5403253466272915e-05 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 2.489430372591037e-13 2.419535412604512e-06 7.144430804518502e-07 1.7874840566240033e-12 1.7635440427125932e-11 +Glycosidase 13 21 3.629554324074932 0.0002839109795025 7.798543689320389 18.135922330097088 0.5112745472223946 0.1951515073440806 2.9064203812520417 1.9684331341643595 1.9501681029822375 0.2619382904734375 7.90888391865223e-09 0.0180235679120217 1.4821215929702348e-07 2.4673681225950384e-10 7.195363185488947e-09 +Host cell receptor for virus entry 12 19 3.149164870688138 0.0016373779035299 4.509708737864078 15.157766990291265 0.7214109752050332 0.2527966464979699 2.499010078306418 1.9009100692398744 1.5211756979359785 0.2791170769282048 5.801111595855173e-07 0.1835089509173778 0.3339976348230559 6.129210716914754e-06 4.3721638653839083e-07 +Heparin-binding 4 9 2.2704680222501272 0.0231792013801597 2.3567961165048543 6.854368932038835 0.2151021415291715 0.4976817002921777 1.5599282492786453 1.096399818915653 1.0317858467489989 0.3203044603738155 0.0034600956668483 0.1178616319260966 0.2223047329091382 0.0033024410276518 0.0074494564855197 +Carboxypeptidase 4 7 2.235898256563046 0.0253584365498951 3.1359223300970873 6.150485436893204 0.9957728306848488 0.1212034427500092 1.2071674596015187 0.4479454254223922 1.8250051834990677 0.2074401112551974 0.0025369657709893 1.0 0.1349531130589082 0.000371706641515 0.0005289198821125 +Protease 20 86 2.099664084218721 0.0357584011180172 20.788834951456312 82.44417475728156 1.1215350835872162 0.3507517256058336 6.07090559629836 8.079357013764625 1.4678877461728397 0.3691345771929886 0.0010578407420123 0.3034250453076603 0.381028039814291 0.0004713467877644 0.0018163681606109 +Transducer 5 7 1.9936657172308023 0.0461885983044487 3.466019417475728 8.91747572815534 -0.1646169358897246 0.5259738353010212 2.4077767773055085 2.0164338021708255 0.961579508666748 0.3124316516206892 0.7538181922262696 0.2731012734555347 0.4724360815693985 0.4776854569740084 0.8373165589367211 +Ion channel 2 10 1.976010849520704 0.0481535484115875 3.3106796116504853 9.844660194174756 0.0369546464975766 0.4589231045677855 2.1923482388215443 2.4035058598872987 1.0709210139105 0.2964139590710569 0.397177145697452 0.2370066357192962 0.1009015630926116 0.1537817902530961 0.5157725074249294 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0e445482f6ac8d304005a79747ee9b1287794fe4 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 96, + "title": "Average number of proteins per term", + "value": 37.875 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..48d32e985d6373fe729c40394dc986ccff9db992 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ef2b069365715f285fde943f741919ab1a93ab1f --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,31 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Receptor 0.8138918503378824 4.322841301137454 1.5403253466272915e-05 0.0014776309481505 0.0014787123327622 54 O43731,Q9UNN8,Q8IX05,Q9NS69,O15173,P15260,P36896,Q9Y5M8,Q15375,P24390,P02786,O15118,P98155,Q99720,Q92673,P20645,P01130,P06756,O75787,P98164,Q9UBG0,Q99523,P30825,P00533,Q14108,O00264,Q9Y624,O15031,Q14739,P35613,P10586,P48960,P11717,Q07954,P15529,Q5KU26,P11279 37 +Glycosidase 0.8167444631455283 3.629554324074932 0.0002839109795025 0.0268911415110502 0.0136277270161216 21 P54802,P04062,O00462,P16278,P06865,P04066,P06280,P07686,P08236,Q99519,Q9BTY2,O00754,P10253 13 +Host cell receptor for virus entry 0.7374829570249272 3.149164870688138 0.0016373779035299 0.1455669314457985 0.0392970696847179 19 Q9Y624,P11279,P06756,O15118,P02786,P35613,Q8WTV0,P00533,P15529,Q14108,Q92692,P01130 12 +Heparin-binding 0.7599827022507596 2.2704680222501272 0.0231792013801597 0.8947480337813037 0.1947753807187027 9 P04114,O94813,P05067,P10586 4 +Carboxypeptidase 0.8098131958302832 2.235898256563046 0.0253584365498951 0.9150598399149736 0.1947753807187027 7 Q9HB40,O75976,P10619,P16870 4 +Protease 0.4111640334614039 2.0996640842187215 0.0357584011180172 0.96967205985619 0.1947753807187027 86 O75844,Q9H3G5,Q9UIQ6,Q96FW1,P10619,Q9HB40,Q16740,P07858,P53634,Q9NZ08,P16870,Q99538,Q15005,Q92643,P67812,O75976,P42892,P55786,O14773,Q8TCT8 20 +Transducer 0.7576311314658541 1.9936657172308023 0.0461885983044487 0.9893241878717398 0.2009887238048873 7 P02786,P48960,P08754,P04899,O14654 5 +Ion channel 0.6746953816495246 1.976010849520704 0.0481535484115875 0.9912416571524684 0.2009887238048873 10 Q9H813,Q9C0H2 2 +Metalloprotease 0.5403374359141812 1.856999742144416 0.063311190768369 0.9981243498291292 0.2337643966832086 27 O75844,O75976,P42892,P16870,Q9UIQ6,P55786 6 +Translocase 0.5286070150446363 1.7718885471051542 0.0764130599376278 0.9995148598880134 0.252953577724561 21 Q13423,P05023,P16615,Q04656,Q03518,Q9HD20,P03886,P20020,P03915 9 +Porin 0.8307641849786709 1.7330187466283995 0.0830923368292573 0.9997583104729436 0.2658954778536234 4 P45880,Q9Y277,P21796 3 +Chloride channel 0.7725296703045166 1.7153788552003593 0.0862757895483421 0.9998269176817404 0.2671766386013176 5 Q9H813,Q9C0H2 2 +Glycosyltransferase 0.5123898369904342 1.6792080506458074 0.0931115035208218 0.999915826819846 0.2793345105624656 35 P04062,Q9BV10,Q9BT22,Q68CQ7,Q10471,Q10472,Q2TAA5,Q16739,O43505,P46977,P43490 11 +Developmental protein 0.3852670304645663 1.6199132303567838 0.1052509173922005 0.9999769154650112 0.2886882305614642 80 Q9NP72,O14786,P48681,Q15375,Q13685,O00115,Q9H0H5,Q92520,Q5SZK8,Q07820,Q99523,P00533,P61962,O94813,O96005,Q8NB78,O15031,O75386,Q07954,Q16352,Q16527,P31751 22 +Monooxygenase 0.8294259036355813 1.3047344481633234 0.1919832871394426 0.9999999987047518 0.4607598891346624 3 P19021 1 +Serine protease 0.572000662867866 1.1875720469016002 0.2350020561343866 0.9999999999932176 0.5013377197533582 8 O14773 1 +Prenyltransferase 0.8433300557194494 1.1054393116803287 0.2689692775638839 0.9999999999999132 0.519103594613583 2 P49356 1 +Tyrosine-protein kinase 0.5096591686642108 1.10204787959509 0.2704408566988876 0.9999999999999286 0.519103594613583 11 Q15375,P00533 2 +Integrin 0.8289085545722863 1.0470706994726686 0.2950669718999519 0.9999999999999972 0.519103594613583 2 P06756 1 +Guanine-nucleotide releasing factor 0.4926065989678179 1.0410530198972932 0.2978509418044384 0.9999999999999982 0.519103594613583 12 P80303 1 +Serine protease inhibitor 0.4737628238499808 0.5344475768265395 0.593031909865215 1.0 0.7907092131536201 6 P05067 1 +Aminopeptidase 0.4048716435674816 0.4781218115837607 0.6325635085842753 1.0 0.8171573057289808 10 Q9UIQ6,P55786 2 +Endonuclease 0.3473569405693842 0.4244705907506512 0.6712226488768012 1.0 0.8413781679904093 21 O00115,O00584 2 +Thiol protease 0.3447062952023729 0.3316796073426062 0.7401312007855587 1.0 0.8950733569751734 32 Q99538,P53634,P07858,Q96FW1 4 +Nuclease 0.3421158730496954 0.3012109306767339 0.7632536551912708 1.0 0.8995603298556422 35 Q8IV08,O00584 2 +Rotamase 0.3226049959840804 0.2511876747151578 0.8016690133012996 1.0 0.927231629842467 21 O95302,Q9NWM8,Q9Y680 3 +Calcium channel 0.5650606358570877 0.1877523786047982 0.8510707681397138 1.0 0.9612093381342652 2 Q9UM00 1 +Decarboxylase 0.3622011812112586 0.1121643077782835 0.910693128808734 1.0 0.977692466903846 7 Q8NBZ7 1 +Signal transduction inhibitor 0.5054080629301756 0.0952095393408518 0.924148393111614 1.0 0.977692466903846 2 P49840 1 +Threonine protease 0.4165274056803102 0.0428927525543176 0.965787026059178 1.0 1.0 3 Q99436 1 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4f2c7deff6dec722388db9b1fac112206803e5f2 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "G-protein coupled receptor", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ACVR1B", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APEH", "APEX1", "APLP2", "APOB", "APOBEC3C", "APP", "APRT", "AQR", "ARFGAP1", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC3", "ASF1B", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATG3", "ATG4B", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAP18", "BAZ1B", "BAZ2A", "BCAT1", "BCAT2", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BPHL", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRD9", "BSG", "BTF3", "BUB1B", "BZW1", "BZW2", "CAD", "CALCOCO1", "CALD1", "CALR", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CBX8", "CCAR1", "CCAR2", "CCDC25", "CCDC47", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD302", "CD320", "CD46", "CDC37", "CDC42", "CDC5L", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CDYL", "CEBPZ", "CECR2", "CELF1", "CELF2", "CEP290", "CEP55", "CERK", "CERS1", "CERS2", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHKA", "CHMP1A", "CHORDC1", "CHRAC1", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT4", "CNOT9", "CNP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPS5", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPE", "CPNE1", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT2", "CPVL", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTDSPL2", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCD", "DCP2", "DCPS", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DPF2", "DPH2", "DPM1", "DPP3", "DPY30", "DPYSL2", "DRG1", "DRG2", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EGFR", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERMP1", "ERO1A", "ESD", "ESPL1", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "F11R", "FADS2", "FAH", "FAHD1", "FAM120A", "FAM120B", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FNTB", "FOXC1", "FOXRED1", "FREM2", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "IQGAP1", "IQGAP2", "IRF2BP1", "IRS4", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KAT7", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KLC1", "KMT2A", "KRR1", "KYAT3", "L3HYPDH", "LAMP1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LNPEP", "LONP1", "LPCAT1", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC8E", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "M6PR", "MACF1", "MAGED2", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MAP1S", "MAP2K1", "MAP2K4", "MAP4K5", "MAPK1", "MAPK3", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MASTL", "MAT2A", "MATR3", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED12", "MED16", "MED17", "MED24", "MED4", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL7A", "MFN1", "MGAT1", "MGEA5", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL58", "MRPL9", "MRPS15", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MYBBP1A", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCL", "NCOA5", "ND1", "ND5", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEK9", "NELFCD", "NELFE", "NES", "NEU1", "NF1", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NUSAP1", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OTUB1", "OTUD4", "OTUD7B", "P3H1", "P3H3", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PALLD", "PAM", "PANK4", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM7", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PHPT1", "PI4K2A", "PI4KB", "PIGA", "PIGK", "PIK3C2A", "PIN1", "PIN4", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS3", "PLXNB2", "PMPCB", "PMS1", "PMVK", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R8", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PPT2", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB18", "RAB1A", "RAB1B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RALA", "RALB", "RALGAPB", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL5", "REL", "RETSAT", "REXO4", "RFC1", "RFC3", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIOX2", "RIPK1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF219", "RNF220", "RNF40", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAGC", "RRAS2", "RREB1", "RRM1", "RRM2", "RRP1B", "RRP8", "RRP9", "RSF1", "RTCB", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARNP", "SARS", "SARS2", "SART3", "SCAF1", "SCAF4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SEC11A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMPDL3A", "SMS", "SMYD2", "SMYD3", "SMYD5", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAMBP", "STAT1", "STAT3", "STAU1", "STK26", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SULT2A1", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TCEA1", "TCERG1", "TCF25", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2IP", "TFAM", "TFCP2", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLK2", "TMCO1", "TMEM109", "TMEM206", "TMOD1", "TMOD3", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM3", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TROVE2", "TRRAP", "TSC2", "TSFM", "TSN", "TSNAX", "TST", "TSTA3", "TTK", "TTYH3", "TUFM", "TULP3", "TWF1", "TXNDC12", "TXNRD1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBR4", "UBR5", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGCG", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UROD", "USP10", "USP11", "USP14", "USP24", "USP28", "USP33", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP3", "UTRN", "UXS1", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VLDLR", "VPS4A", "VPS4B", "VRK1", "WARS", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF3", "ZADH2", "ZC3H14", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZDHHC13", "ZFR", "ZMPSTE24", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512B", "ZNF638", "ZNF687", "ZRANB2"], "leading_proteins": ["AAMP", "ACVR1B", "ADGRE5", "AKT2", "ALG1", "ALG11", "ALG12", "APOB", 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a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d128e9d60f29357bc43c1d485ce2f2748d1ff852 --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e66d703d5e95436ab73deb8661be84210aac8f0a23cd4cfa52d4e74772f730f9 +size 97475 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6e1f0ccb7c6466f2fcd29d797eafafc918371d2a --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 308 572 4.510621036636289 6.463810681589521e-06 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 5.955996784773168e-75 1.1441187315475326e-12 1.117380929956518e-19 1.0521480656734274e-51 1.2983735130900468e-78 +CD markers 23 27 3.576627489246228 0.0003480556064776 6.548543689320389 16.62378640776699 0.159361413045758 0.3347758559744795 3.625700175504636 4.1209525283344535 1.5119526885132668 0.3016304730463651 2.495222221849325e-07 0.0145949948181238 0.0195066935662917 3.933207093350709e-08 6.445659977586138e-09 +Predicted secreted proteins 33 62 3.2996359707076035 0.0009681031694372 15.29368932038835 51.737864077669904 1.393291060716792 0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 3.8804450947995733e-08 0.0002738189551016 0.0002507561403829 8.174816675563357e-06 8.4566559434241e-08 +Transporters 169 370 2.141903079072726 0.0322012820487704 108.9004854368932 367.3009708737864 1.469396346451591 0.4764419032567517 40.40141182476491 35.10022679965902 2.352674986871393 0.4490473364946538 1.44860614618735e-30 0.0120254404772823 0.0001730299353328 2.569806647138743e-17 3.651002182391541e-32 +Candidate cardiovascular disease genes 4 12 1.996996225022323 0.045825593073534 2.563106796116505 9.29368932038835 0.1164468151756199 0.468077533298839 1.894908368881901 1.612649926975264 1.0410221205625372 0.2788935851718957 0.0159423888090386 0.1635258499471353 0.048990890514732 0.0018532910789756 0.0081853110588452 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0c2fafdc6e0f0a6f8dd6b683732b94ca448a51fc --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 473.04761904761904 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..be24067d93d1d9de0167e844719d989f02ea0134 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dace741577e5843a2dde3c322b6627627accd6b4 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.7098573832194995 4.510621036636289 6.463810681589521e-06 0.0001357312506943 6.787001215670048e-05 572 O43731,Q9NS69,Q8IX05,O43493,O60499,O60830,O60637,O43169,Q8IV08,Q15070,Q8NC54,Q9C0H2,Q9Y287,P15260,Q13505,Q9Y282,Q99805,P36896,P05067,Q99595,Q8NEW0,Q86UE4,Q15375,Q15012,P24390,P02786,P43307,P98155,O95197,Q86VP1,Q68CQ7,Q8NBN3,Q9NRX5,Q14849,Q9BXS4,Q9NX00,O43657,Q92673,Q8IZA0,Q7Z3D4,Q9NQX7,Q9NQC3,P19021,Q9P0T7,O75071,Q8TB61,Q9UBG0,Q06481,Q5SZK8,Q96G23,Q99523,P30825,Q7L0J3,Q9H1E5,Q86Y39,P11117,O43676,Q9H2C2,Q9H813,Q9Y2R0,Q9BSK2,O15031,O75976,P12235,P42892,P48960,P12236,P04439,Q9NV96,Q92896,Q9UBX3,Q9NX62,P11717,Q07954,Q9H061,P51648,Q16739,Q5KU26,P11279,O00461,O95772,Q8TCT8,Q3SXM5,Q9BQE5,Q9HC07,Q9UNN8,O75844,Q6UXD5,Q16625,P09601,Q9P2W9,Q9UIQ6,Q96A26,Q08722,Q7KZN9,O00592,O15127,O15173,Q13277,Q8IYS2,Q8WY22,Q9H9S5,Q5ZPR3,P30519,O15118,P10321,Q93050,Q9HD45,O15400,P53634,O14925,Q10472,Q8TAA9,Q9Y619,Q9UDW1,Q9HD20,Q9BTX1,Q9H490,P01130,O75438,Q13641,Q9NZ45,P06756,P98164,Q13423,Q9GZM5,P16615,Q04656,Q96A57,Q92542,Q15904,Q8NE01,Q9H8H3,O94813,Q8WVC6,Q14108,Q92581,Q15629,O96005,A2RU67,Q6ZRP7,Q14574,O95249,Q13190,Q9H3K2,P35613,O15260,P10586,Q9BV10,Q03518,P43121,P51790,P38435,P15529,Q86XL3,P11166,Q4KMQ2,Q86Y82,Q8WVQ1,Q96J84,O95202,Q567V2,Q96QD8,O75964,Q9Y2W6,P39210,Q9UDX5,Q70HW3,Q8N4V1,Q9BUR5,P51798,Q8N511,O60725,Q14126,P04920,Q8IUH4,Q9H4I3,Q9BUN8,Q4ZIN3,Q96A33,Q14534,Q9Y5M8,P56192,O94919,Q8NCC3,Q8NHS3,Q9HDC9,Q99720,Q9UG56,Q9HC21,P14672,O95070,O95831,Q07065,P20645,P33908,P03886,Q6P4A7,Q9UNK0,Q92544,O75787,P01889,Q9BXK5,P08195,Q9Y3B3,Q96KA5,Q9UPR3,P00533,Q15005,Q6NUQ4,Q96KC8,Q96JJ7,Q92643,P67812,O00264,P27544,Q9NZJ7,Q9Y624,P51809,Q14739,Q8NBX0,Q8WTV0,Q9Y487,O43760,Q7KYR7,Q8TCT9,O76024,Q15363,P16435,O14828,O15269,Q9NZ01,Q8NHH9,P13073,Q96N66,P55011,A1L0T0,P05023,P05141,Q9BT22,Q9Y6M7,Q9Y6C9,O95470,Q9P0J0,Q9NX40,Q9H3N1,Q2TAA5,Q15526,Q15043,O14786,P19022,O14681,P27824,Q6DD88,Q16850,Q14789,Q969E2,Q9NVH1,Q99735,Q96SK2,P46977,P20020,P03915,O15258,Q9P0S9,Q9NR28,P57088,Q06136,Q15800,Q7RTS9,P00403,P26572,Q9NPF0,Q8IWA4,O14735,Q9HCU5,P60228,Q92692,P50402,O95169,P54709,Q6NUM9,Q9P035,Q3ZCQ8,Q8IXU6,O43292,Q96AG4,Q96SY0,P48651,Q92804,P57105,O00400,Q96GQ5,Q15392,O94901,Q86VR2,P04843,P62942,Q5SNT2,P05556,O75915,Q5SQN1,Q99442,Q9H6K4,Q70UQ0,Q96TC7,O60831,O43808 308 +CD markers 0.7983931118057896 3.5766274892462273 0.0003480556064776 0.0072837837588583 0.0024363892453436 27 Q9UNN8,Q8IX05,P05556,Q08722,P15260,O14786,Q5ZPR3,P19022,P02786,P06756,Q9UBG0,P08195,Q9NPF0,Q92692,Q9Y624,P54709,P35613,P48960,P43121,P11717,Q07954,P15529,P11279 23 +Predicted secreted proteins 0.6364988246549168 3.2996359707076035 0.0009681031694372 0.0201345510794288 0.0050825416395458 62 P61916,P80303,O75629,Q9BUR5,Q9HB40,P04114,Q9Y287,Q08431,P07858,O14786,Q9H9S5,P05067,Q08380,P02786,O94919,O00584,Q07021,O60888,Q8N128,Q9NZ08,Q92673,P07942,Q9UM22,P19021,Q02818,P00533,Q9BTY2,O94813,Q9Y251,P48960,P14543,Q9Y4P3,P43490 33 +Transporters 0.5622682339882132 2.141903079072726 0.0322012820487704 0.4970950715984449 0.0751363247804644 370 O94901,O96008,P04843,P62942,O60637,P05556,Q96L92,O75915,Q12834,Q15070,Q9Y512,Q9C0H2,Q9Y287,P07602,Q99442,Q9NQZ5,Q99805,P05067,O60831,Q8NEW0,O43808,P24390,P02786,O95067,Q14849,Q9BXS4,Q92673,Q9Y320,Q8TEX9,Q9P0T7,Q8TBA6,Q8TB61,O15126,O14678,Q99523,P30825,Q9H2C2,Q9H813,Q8IY95,Q9H2D1,Q9BSK2,P61421,P49755,O75381,P12235,Q15758,P48960,P12236,P04439,Q9NV96,Q9UBX3,O60826,P11717,Q07954,O00429,Q9H061,Q16739,P11279,Q8TCT8,Q96CW1,Q9HC07,O75844,Q5T8D3,Q8TCJ2,Q16625,Q9UPT5,P45880,Q9H9B4,Q92621,Q08722,Q9BRK5,O15127,Q13277,Q8WY22,Q96P70,O15118,Q93050,O00560,Q8TAA9,Q9Y619,Q9HD20,Q9BTX1,P06756,P98164,Q9GZM5,P16615,Q04656,Q96A57,Q15904,Q8NE01,Q14108,Q92581,Q15629,O96005,Q13190,P35613,O15260,Q03518,P11166,Q4KMQ2,O95202,Q96QD8,P61916,P39210,Q70HW3,Q8N4V1,Q9BUR5,P51798,Q8N511,P04920,Q8IUH4,Q9BUN8,Q96A33,P40855,Q8NHS3,Q99720,Q9HC21,P14672,Q07065,P20645,Q6P4A7,Q92544,O75787,P08195,Q9Y3B3,Q6NUK1,Q92973,Q96JJ7,Q9NZJ7,P54105,Q8WTV0,O75955,Q8NFH4,O76024,Q15363,O14828,O60313,Q8NHH9,P13073,P36543,Q96N66,P55011,P05023,P05141,Q9Y6M7,Q9Y6C9,Q9H3N1,Q15043,O14786,Q16891,O14681,Q6DD88,Q07021,Q8IYU8,Q969E2,Q9BPX6,P46977,P20020,O15258,P57088,P00403,Q8IWA4,Q9HCU5,P54709,Q8IXU6,Q96AG4,P57105,P51149,O00400 169 +Candidate cardiovascular disease genes 0.6575270845107175 1.996996225022323 0.045825593073534 0.6265925002017841 0.0874852231403832 12 P06865,Q9UNN8,P07858,Q07954 4 +FDA approved drug targets 0.3609695503476757 1.1003739279368652 0.2711692333683728 0.998696351083694 0.3839355710446054 117 Q9UNN8,Q96QD8,P55011,P62942,P05023,P05556,P05141,P15260,P05067,Q14534,P02786,P49721,Q99720,Q16850,P42345,P35610,Q16637,P20645,P03886,P20020,P49356,P06756,Q13423,P16615,P00533,Q7L0J3,P23786,P10253,P00374,P12235,P21964,P12236,P38435,Q16739 34 +RAS pathway related proteins 0.3548515049839167 0.4134829509368016 0.6792528110248657 0.999999999957399 0.8390770018542458 31 P20339,P17612,P61020,P00533,P0DP25,P51148,P11233,P31751 8 +Disease related genes 0.2531436765751413 0.2314945073701369 0.8169306520505419 0.9999999999999996 0.9530857607256324 991 Q13501,Q8IV08,Q9Y287,P07602,P15260,P07858,P36896,P05067,P02786,O00584,P98155,P04066,P06280,P50897,Q92673,Q86UE8,O14949,Q9UHX1,P16278,P06865,Q5SZK8,Q99523,Q86Y39,P11117,O43676,Q9H2C2,P17900,Q9Y2R0,Q9H2D1,P10253,O00462,P12235,P42892,O75503,P04439,P09622,Q9NX62,Q07954,O14773,Q9H061,P51648,Q9HC07,O75844,Q16625,P09601,P10619,Q7KZN9,P04114,Q99519,Q16740,Q9H9S5,P54802,O15118,P10321,P53634,Q5HYI8,Q8TAA9,Q9Y619,O00754,P15586,Q9H490,P01130,P10644,P98164,Q13423,Q96JJ3,P16615,Q04656,Q92542,P07686,Q15904,Q14108,Q92581,O43505,Q14574,P21964,P10586,Q9BV10,Q03518,Q15555,P38435,P15529,P08236,Q86XL3,P11166,Q4KMQ2,Q8WVQ1,Q5XKP0,P31751,P61916,P39210,Q70HW3,P51798,Q8N511,Q9Y6M9,Q14126,P53701,Q96J02,Q96A33,Q96PU5,P04062,P56192,P40855,Q8NHS3,Q99720,Q9HC21,P14672,O95831,Q969T9,P0DP25,Q9Y6B6,P07942,P03886,Q6P4A7,Q13510,O75787,P01889,Q15042,P38571,Q6NUK1,Q10471,P00533,Q92643,P23786,P27544,Q6DKK2,Q96HY6,P46020,Q14739,Q9Y487,Q9HB90,Q8NFH4,Q6NUQ1,O76024,P16435,O60313,O15269,Q9NZ01,Q9Y4P3,P13073,P36543,Q96N66,P05023,Q9BT22,O95470,Q9P0J0,Q2TAA5,Q15526,Q15043,P07237,Q9NVI7,O14681,Q6DD88,Q07021,Q16637,Q01105,Q9BPX6,P46977,P03915,O14979,Q9BXW9,Q9NR28,Q06136,P55795,Q15800,Q01844,Q7RTS9,P00403,Q9NPF0,Q9NWM8,P50402,O95169,P00374,P35637,Q96C86,Q3ZCQ8,Q92733,P22695,O43292,P78318,P48651,Q92804,P07196,P51149 184 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..84b83aded1ca8afbab5600e1c0b90084f709a8dc --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "G-protein coupled receptors", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC2", "ASCC3", "ASF1B", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRD8", "BRD9", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C14orf2", "C16orf58", "C17orf75", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C20orf27", "C2CD5", "C5orf15", "C5orf24", "C8orf33", "CAB39", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASP2", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX4", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC25", "CCDC47", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2AP", "CD2BP2", "CD302", "CD320", "CD3EAP", "CD46", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CDV3", "CDYL", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPI", "CENPM", "CENPV", "CEP170", "CEP290", "CEP44", "CEP55", "CERK", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLIP1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT4", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7C", "CPD", "CPE", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT2", "CPVL", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPH2", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM213A", "FAM234B", "FAM3C", "FAM49B", "FAM50A", "FAM83D", "FAM91A1", "FAM98A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FREM2", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLM2", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INTS10", "INTS12", "INTS13", "INTS14", "INTS2", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRGQ", "IRS4", "ISCU", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "IVD", "IWS1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA2013", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIRREL1", "KLC1", "KLHDC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L3HYPDH", "LAMB1", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8E", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAP4K5", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED12", "MED16", "MED17", "MED24", "MED4", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL7A", "MFGE8", "MFN1", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRC2", "MRE11", "MRFAP1", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL58", "MRPL9", "MRPS15", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MVB12A", "MYBBP1A", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NBR1", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NENF", "NES", "NEU1", "NF1", "NFATC2IP", "NFS1", "NHLRC2", "NHP2", "NID1", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PAM", "PANK4", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF14", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHPT1", "PI4K2A", "PI4KB", "PICALM", "PIGA", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIN4", "PINX1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL5", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF219", "RNF220", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAGC", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCB", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERINC1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMPDL3A", "SMS", "SMU1", "SMYD2", "SMYD3", "SMYD5", "SNAP23", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TAX1BP1", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLCD1", "TLK2", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM43", "TMEM59", "TMEM87A", "TMEM9", "TMEM97", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TROVE2", "TRRAP", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSR1", "TSR2", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TULP3", "TWF1", "TWISTNB", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAC14", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VLDLR", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR73", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "XAB2", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YIPF3", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCD4", "ACBD5", "ACP2", "ACVR1B", "ADGRE5", "AIFM1", "AKT2", "ALDH3A2", "ALG1", "ALG11", "ALG12", "ANKLE2", "ANO6", "AP2M1", "APLP2", "APMAP", "APOB", "APOL2", "APOO", "APP", "ARL6IP5", "ARV1", "ASAH1", "ATAD3A", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5L", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1E1", "ATP7A", "B4GAT1", "BCL2L13", "BRI3BP", "BSG", "BTN2A1", "C16orf58", "C19orf70", "C1QBP", "C5orf15", "CALM3", "CANT1", "CANX", "CCDC22", "CCDC47", "CCNB2", "CD276", "CD302", "CD320", "CD46", "CD47", "CDC20", "CDH2", "CDIPT", "CERS1", "CERS2", "CISD1", "CKAP4", "CLCN3", "CLCN7", "CLN5", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CNNM3", "COA3", "COLEC12", "COMT", "COX15", "COX2", "COX4I1", "CPD", "CPT2", "CREG1", "CTSA", "CTSB", "CTSC", "CUTA", "CYB5B", "CYP51A1", "DCAKD", "DCPS", "DDRGK1", "DERL1", "DHCR24", "DHFR", "DIABLO", "DLD", "DNAJC1", "DNAJC11", "DNM1L", "DSC3", "DSG2", "DYM", "ECE1", "EFCAB14", "EGFR", "EI24", "EIF3E", "ELMO2", "EMD", "ENDOD1", "EPDR1", "EPHA7", "ERAP1", "ERGIC3", "EWSR1", "EXOC7", "F11R", "FAM162A", "FAM177A1", "FAM234B", "FANCD2", "FKBP14", "FKBP1A", "FKRP", "FLOT1", "FNTB", "FREM2", "FUCA1", "FUCA2", "FUS", "GAA", "GALNT1", "GALNT2", "GBA", "GGCX", "GHITM", "GLA", "GLB1", "GLG1", "GLT8D1", "GM2A", "GNS", "GOLGA5", "GOLGB1", "GOLIM4", "GOSR1", "GPAA1", "GUSB", "HACD3", "HCCS", "HEXA", "HEXB", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMOX1", "HMOX2", "HNRNPDL", "HNRNPH2", "HPSE", "HSDL1", "ICMT", "IFNGR1", "IGBP1", "IGF2R", "IKBIP", "ILVBL", "IMMT", "IMPAD1", "INTS14", "IPO4", "IPO9", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "KDELR1", "KDELR3", "KDSR", "KIAA0319L", "KIAA2013", "KIRREL1", "LAMB1", "LAMP1", "LAPTM4A", "LBR", "LDLR", "LETM1", "LGALS3BP", "LIPA", "LNPEP", "LRP1", "LRP2", "LRRC59", "LYSMD3", "M6PR", "MAN1A1", "MAN2B1", "MANBA", "MAPRE2", "MARS", "MBOAT7", "MCAM", "METTL7A", "MFGE8", "MFN1", "MFSD8", "MGAT1", "MGST2", "MICU1", "MICU2", "MMGT1", "MPV17", "MPV17L2", "MRC2", "MSMO1", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTOR", "MTX1", "NAGLU", "NAMPT", "NCSTN", "ND1", "ND5", "NDC1", "NDUFA11", "NDUFA13", "NDUFB1", "NDUFB3", "NDUFB8", "NDUFB9", "NECTIN2", "NEDD4L", "NEFL", "NEU1", "NID1", "NNT", "NPC1", "NPC2", "NRP1", "NUCB1", "NUCB2", "NUP205", "NUP37", "OCIAD1", "OCLN", "OPA1", "OPA3", "OXA1L", "P4HB", "PAM", "PEX14", "PEX19", "PGRMC1", "PGRMC2", "PHKA1", "PIGK", "PIGU", "PISD", "PLA2G15", "PLD3", "PLXNB2", "PODXL", "POR", "PPT1", "PRAF2", "PRCC", "PREB", "PRKACA", "PRKAR1A", "PROCR", "PSAP", "PSMB2", "PTDSS1", "PTPRF", "PUF60", "QSOX2", "RAB3GAP1", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABL3", "RALA", "RER1", "RETREG3", "RETSAT", "RINT1", "RMDN3", "RNASET2", "RPN1", "RRAGC", "RTN3", "RTN4", "SAMM50", "SAR1B", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCPEP1", "SDCBP", "SDF4", "SEC11A", "SEC62", "SERINC1", "SET", "SEZ6L2", "SFXN1", "SFXN4", "SGPL1", "SIGMAR1", "SLC12A2", "SLC1A5", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC2A1", "SLC2A4", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A6", "SLIT2", "SMG5", "SMN1*", "SNAP47", "SNX27", "SOAT1", "SORL1", "SORT1", "SPCS2", "SPPL2A", "SPTLC1", "SQLE", "SQSTM1", "SRPRB", "SSR1", "STARD3", "STARD3NL", "STARD7", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "SUN1", "SURF1", "SURF4", "SV2A", "SYNGR2", "SYNJ2BP", "TAF15", "TAP1", "TAX1BP1", "TBL2", "TDRKH", "TECR", "TFRC", "TGOLN2", "TIMM17A", "TIMM17B", "TIMM23", "TIMM50", "TLK2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED7", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM59", "TMEM87A", "TMEM9", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TOMM22", "TOMM40", "TPBG", "TPP1", "TRABD", "TRAM1", "TSPAN3", "TSPAN6", "TTC19", "TTYH3", "UGCG", "UQCR10", "UQCRC2", "UQCRQ", "VAMP7", "VANGL1", "VDAC2", "VLDLR", "WBP2", "WFS1", "YIF1A", "YIPF3", "ZDHHC13", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/idx2term.json 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0000000000000000000000000000000000000000..4d66f9041489d835211bcaf3008c141e5f2a51c3 --- /dev/null +++ b/protein_atlas_subcellular_location_all/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:982dcee14c9095895f7c17e386ac4a13e553a80603b96d77b2c8bad7f8c9c5eb +size 78457 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7efa68a0443ea1d82d9b85e92e10728ce1e5394d --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Golgi apparatus 75 177 2.913704784475889 0.0035716749135425 46.45873786407767 176.03155339805826 1.3643789213018729 0.3972771337532677 14.511319530749702 26.453870355965975 1.6568954592349954 0.4161874156663988 1.1950571634932348e-08 4.761309416360381e-05 1.3030976654823444e-05 1.6978983877486e-09 2.2240240852523868e-08 +Centriolar satellite 5 30 1.9639503750429668 0.0495358471059947 6.354368932038835 28.046116504854368 0.5330334825095895 0.5754639941794782 3.863025543447266 4.860211896177677 0.8074973811315178 0.3370904262689401 0.3298668437263022 0.1069397385760632 0.1006907935425077 0.0625424494257227 0.4967319288630961 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3ddd3809ba2cf1446fefbe512f973e9ec4bab208 --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3053, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 144.0909090909091 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6425941c2f437b1b09953de2ae92a5c71123264f --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C310/C310_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a2471628fdcb55a0308375b68839aa2812dbf61c --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,13 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Golgi apparatus 0.5497721282611409 2.913704784475889 0.0035716749135425 0.1113717193465686 0.0469456777418537 177 Q9HC07,O43493,Q6IAA8,P80303,P09601,O60499,A1L0T0,O60637,Q9BRK5,Q9HB40,Q8NC54,Q9Y287,O15127,Q8IUH4,Q15043,Q8IYS2,P05067,Q9H9S5,Q8NEW0,O95302,Q15012,P24390,O14681,O95067,Q9H4A5,Q6P4E1,Q93050,Q9HD45,Q9H0U4,Q9UG56,Q8NBN3,O95070,Q14789,P50897,Q969E2,Q8IZA0,Q9UID3,P33908,P19021,O15258,Q8TBA6,Q969S3,O75071,Q02818,Q92520,Q9GZM5,P16278,Q04656,Q86SF2,Q99523,Q16706,Q10471,Q7RTS9,Q6NUQ4,Q5VU43,P67812,Q9NWM8,Q6ZRP7,Q8NBJ4,Q13190,O15260,P10586,O43760,P04439,O75955,Q92896,Q8IXU6,Q9NX62,P11717,Q6NUQ1,Q86Y82,Q8WVQ1,Q5KU26,O00461,Q96GQ5 75 +Centriolar satellite 0.553431587821386 1.9639503750429668 0.0495358471059947 0.8129836899606079 0.2797541687314017 30 P98155,O43169,O00592,P41208,Q86UY6 5 +Lysosomes 0.6458658461476646 1.9321808223691228 0.0533371913683407 0.8361503913735455 0.2797541687314017 12 O15400,P51149,P02786,Q8WTV0 4 +Endoplasmic reticulum 0.4703032297526097 1.851046772785744 0.064162824509139 0.8878989508298518 0.2797541687314017 191 O43731,Q9Y680,Q9H3G5,P04843,Q9P2W9,P05556,O43169,Q9BT22,O75915,Q8IV08,O95470,P62820,Q9H3N1,Q99442,Q15043,Q70UQ0,Q9BUN8,Q9NR31,Q4ZIN3,O60831,Q96A33,P07237,Q86UE4,O14681,P43307,P13674,Q92791,P27824,O95197,Q6DD88,Q9H0U4,Q16850,P35610,Q5HYI8,Q14849,Q96CN7,Q9Y6B6,Q14257,Q99735,Q9NQC3,O43852,Q8NF37,Q96KA5,Q96G23,Q96A57,Q15800,Q6NUQ4,Q96KC8,Q9HCU5,P35790,O96005,A2RU67,O00264,P27544,Q96HY6,P50402,P21964,O15260,Q9P035,Q9BV10,Q15293,Q03518,Q8TCT9,O43292,Q96AG4,Q86XL3,P48651,P51648,O15269,Q9NZ01,Q8NHH9 71 +Nuclear membrane 0.4747996687097117 1.772590473327984 0.0762965914722004 0.9271257623340136 0.2797541687314017 60 O94901,Q14739,O75976,O94919,Q86VR2,O15260,Q5SNT2,O00560,Q96G23,Q96SK2,Q9H1E5,Q96SY0,O14735,P67812,Q9BTX1,Q13277,P50402 17 +Vesicles 0.4876232956734171 1.344791726879465 0.17869250269408 0.9984909939499528 0.589685258890464 312 Q13501,O75629,O60499,Q9UMR5,Q9Y287,P07602,P07858,P05067,Q15012,P24390,P98155,P04066,Q14849,P50897,Q9P0T7,Q9NRY5,Q8TB61,P16870,P16278,P06865,Q06481,Q9H2C2,P17900,Q14596,P10253,O00462,P11717,Q07954,Q13137,Q5KU26,O95772,Q8TCT8,Q3SXM5,Q08722,P10619,P04114,O00592,Q99519,O15127,Q9NUD5,Q13277,Q5ZPR3,Q96P70,O95302,P30519,O15118,P61020,Q93050,Q9HD45,P53634,O00754,Q9HD20,P98164,Q99538,Q8TCT0,Q92581,Q9Y251,P35613,P21964,P51790,P08236,Q86Y82,P31751,P52789,Q8IUH4,Q96J02,Q14534,Q8NCC3,Q8NHS3,O95070,Q8N128,Q6P4A7,Q9UNK0,P38571,P46020,P51809,Q8NBX0,Q8WTV0,Q9Y487,Q9HB90,O75955,Q8WZA9,Q15363,P16435,O14828,Q6IAA8,P55011,A1L0T0,Q8IXH7,Q92572,P13674,Q92791,Q14254,Q969E2 94 +Endosomes 0.521834431235703 1.1728404553221752 0.2408597915274108 0.99988763635263 0.6049955210089695 11 P51148,P02786 2 +Cell Junctions 0.4125177344225892 0.937831997531852 0.3483307545203158 0.9999992707130444 0.6049955210089695 47 Q9Y624,P19022,Q16625,P00533,Q14126,O15511,Q99519,O43657,Q5KU26,Q92692,Q9BW91,Q14574,P43490 13 +Focal adhesion sites 0.3744273247956074 0.5735978696004579 0.5662399537401039 0.9999999999989304 0.8124312379749317 29 P06756,Q9Y487,O60888,Q9Y6M7,Q969Q5,P11233 6 +Microtubules 0.3491154123915687 0.4035254467122661 0.6865617186400739 1.0 0.9300071043776676 52 Q9P0T7,Q9Y624,P54105,Q02818,O75629,O60830,Q13685,P55209 8 +Lipid droplets 0.3753219261590354 0.3365491761785125 0.7364567746948163 1.0 0.934733598651113 11 Q9H8H3,Q01105,Q969E2 3 +Peroxisomes 0.3214957493973499 0.1087054978773483 0.9134360810254296 1.0 1.0 14 Q15067,O75381,P40855,O43808 4 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1a622eb9b910df33eb2f23d11d703a1f88cc84b6 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACVR1B", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG2", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOBEC3C", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC5", "ARV1", "ASCC2", "ASCC3", "ASF1B", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1B3", "ATP2B1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "AURKA", "BABAM1", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BDH2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRD8", "BRD9", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C14orf2", "C16orf58", "C17orf75", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C20orf27", "C2CD5", "C5orf15", "C5orf24", "C8orf33", "CAB39", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASP2", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX4", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC25", "CCDC47", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD276", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD46", "CD47", "CDC123", "CDC20", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKN2AIP", "CDS2", "CDV3", "CDYL", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPI", "CENPV", "CEP170", "CEP290", "CEP55", "CERK", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLINT1", "CLIP1", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "CORO1B", "COTL1", "COX15", "COX4I1", "COX5B", "COX6C", "CPD", "CPE", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF4", "CPSF6", "CPSF7", "CPT2", "CPVL", "CREG1", "CRKL", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAKD", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DPF2", "DPH2", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DTYMK", "DUSP12", "DUSP3", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERH", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETFA", "ETFB", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM234B", "FAM3C", "FAM49B", "FAM50A", "FAM83D", "FAM91A1", "FAM98A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FREM2", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLM2", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GPAA1", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM3", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTPBP1", "GTPBP4", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS2", "HAUS3", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HGH1", "HIBCH", "HINT2", "HIP1", "HIRA", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HPSE", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "IAH1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IFNGR1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INTS10", "INTS12", "INTS13", "INTS14", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRGQ", "ISCU", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "IWS1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA2013", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KLHDC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L3HYPDH", "LAMC1", "LAMTOR1", "LAMTOR2", "LANCL1", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAD2L1", "MAGED2", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAP4K5", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED12", "MED16", "MED17", "MED4", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL7A", "MFGE8", "MFN1", "MFSD3", "MFSD8", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPRIP", "MPST", "MRE11", "MRFAP1", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL58", "MRPL9", "MRPS15", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MVB12A", "MYBBP1A", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NBR1", "NCAPD2", "NCAPH", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB1", "NDUFB4", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEFL", "NEFM", "NELFCD", "NELFE", "NES", "NEU1", "NF1", "NFATC2IP", "NFS1", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PAM", "PANK4", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE4DIP", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF14", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHPT1", "PI4K2A", "PI4KB", "PICALM", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIN4", "PINX1", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIF", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTK2", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PXN", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "RECQL5", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNF14", "RNF2", "RNF219", "RNF220", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RRAGC", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCB", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERINC1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC9A6", "SLFN11", "SLIRP", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMPDL3A", "SMS", "SMU1", "SMYD2", "SMYD3", "SMYD5", "SNAP23", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPECC1", "SPECC1L", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SQLE", "SQSTM1", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRN", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TAX1BP1", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM126A", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM87A", "TMEM9", "TMEM97", "TMOD3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TROVE2", "TRRAP", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSR1", "TSR2", "TST", "TSTA3", "TTC1", "TTC19", "TTC37", "TTC38", "TTC4", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TULP3", "TWF1", "TWISTNB", "TXLNA", "TXLNG", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VLDLR", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR46", "WDR5", "WDR6", "WDR61", "WDR77", "WDR82", "WIPI2", "WIZ", "XAB2", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YIPF3", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZFR", "ZFYVE16", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAMP", "ACOX1", "AKT2", "ALDH3A2", "ALG1", "ALG12", "ANKLE2", "AP3S1", "APLP2", "APOB", "APP", "ARL6IP5", "ARPC5", "ARV1", "ATL2", "ATL3", "ATP13A1", "ATP6V0A1", "ATP6V0A2", "ATP7A", "BSG", "C16orf58", "C5orf15", "CALCOCO2", "CALU", "CANT1", "CANX", "CCDC47", "CCNB2", "CD276", "CD47", "CDH2", "CDIPT", "CERK", "CERS1", "CERS2", "CETN2", "CHKA", "CLCN3", "CLNS1A", "CLPTM1", "CLPTM1L", "COLEC12", "COMT", "CPD", "CPE", "CPVL", "CREG1", "CTSA", "CTSB", "CTSC", "CUTA", "CYB5B", "CYP51A1", "DDRGK1", "DERL1", "DNAJC1", "DSC3", "DSG2", "DYM", "EFCAB14", "EGFR", "EI24", "EMD", "ENDOD1", "F11R", "FAM114A2", "FAM177A1", "FAM234B", "FAM3C", "FKBP14", "FKBP7", "FKBP9", "FKRP", "FLOT1", "FLOT2", "FUCA1", "GAA", "GALNT2", "GALNT7", "GLB1", "GLG1", "GM2A", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLM2", "GOLPH3L", "GPAA1", "GUSB", "HACD3", "HEXA", "HK2", "HLA-A", "HM13", "HMOX1", "HMOX2", "HPSE", "HSDL1", "IGF2R", "IKBIP", "ILVBL", "IMPAD1", "INTS14", "IPO9", "IRGQ", "ISOC1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "KDELR1", "KDELR3", "KIAA0319L", "KIAA2013", "LAMTOR1", "LAPTM4A", "LBR", "LGMN", "LIPA", "LPCAT1", "LRP1", "LRP2", "LRRC59", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "METTL7A", "MFSD8", "MGST2", "MSMO1", "MTDH", "NAA40", "NAMPT", "NAP1L1", "NBR1", "NDC1", "NECTIN2", "NELFCD", "NEU1", "NPC1", "NUCB1", "NUCB2", "NUDT9", "OCLN", "P3H4", "P4HA1", "P4HB", "PAM", "PDE4DIP", "PEX14", "PEX19", "PGRMC1", "PHKA1", "PISD", "PLA2G15", "PLD3", "PODXL", "POR", "PPT1", "PPT2", "PRAF2", "PREB", "PSAP", "PTDSS1", "PTPRF", "QSOX2", "RAB1A", "RAB1B", "RAB24", "RAB5B", "RAB5C", "RAB7A", "RABL3", "RALA", "RCN1", "RCN2", "RER1", "RETREG3", "RINT1", "RPN1", "RRAGC", "RTN3", "RTN4", "SAR1A", "SAR1B", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCCPDH", "SCPEP1", "SDCBP", "SDF4", "SEC11A", "SEC62", "SET", "SFXN4", "SGPL1", "SLC12A2", "SLC25A17", "SLC30A7", "SLC35B2", "SLC35F2", "SLC39A14", "SLC4A7", "SLC9A6", "SOAT1", "SORT1", "SPPL2A", "SPTLC1", "SQLE", "SQSTM1", "SSR1", "STARD3", "STARD3NL", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "SUN1", "SURF4", "SYNGR2", "TAP1", "TECR", "TFRC", "TGOLN2", "TIMM17B", "TM9SF3", "TMED2", "TMEM165", "TMEM201", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM87A", "TMEM9", "TMX1", "TMX4", "TSPAN3", "TSPAN6", "VAMP7", "VLDLR", "VPS51", "YIF1A", "YIPF3", "ZCCHC3", "ZDHHC13", "ZNF622"]} \ No newline at end of file