term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 Sphingolipid metabolism 18 27 3.5774645834441707 0.00034694321028 11.00242718446602 26.135922330097088 1.1708540815039898 0.1757583754913391 4.192861933829232 2.1968580551223003 2.1941615995620167 0.2567064655985949 2.1214966321541079e-10 0.0356328568827733 2.690584339783567e-05 2.30996546554735e-08 4.7437155331330864e-11 Glycosphingolipid metabolism 12 17 3.5430376436759747 0.0003955462364386 7.514563106796117 15.521844660194176 0.6340330218232789 0.1371235236408302 2.3948329397108954 1.2175929202976112 2.2116324239586063 0.2290247571497847 2.7278873335113235e-09 0.0108643857486399 1.4194050004739812e-05 3.292573095472588e-09 1.6712170470498703e-09 Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 14 23 3.431459714842592 0.0006003422891591 6.014563106796117 17.274271844660195 0.870961683103299 0.329566970411291 2.8591161566949044 2.4465188670593117 1.2657234914365352 0.3108311955329007 2.526351715661311e-07 0.0295498589150116 1.4885597454595322e-05 0.0003789274231414 4.0901831486735546e-08 Slc mediated transmembrane transport 17 26 3.348977649640557 0.0008111033845985 8.672330097087379 21.910194174757283 1.4735742044813558 0.239038892478899 4.348519601656105 3.146764860695784 1.3934177975338422 0.3068823132077037 1.0038780594540254e-07 0.3867386931517215 0.0731929968318565 0.0007457783870921 1.446687272672473e-06 Glycosaminoglycan metabolism 9 14 3.230258711052642 0.0012367824898804 6.563106796116505 14.388349514563108 0.750167459040055 0.1742505874253542 2.387954817808654 2.3973407990867264 1.8682770414846892 0.2409021330213527 0.0004795230822878 0.2870659866655126 0.0045315560193572 6.419800009101929e-06 0.0019108778393583 Transport of small molecules 57 150 3.1871449064614983 0.0014368476869268 41.730582524271846 151.96601941747574 1.4265613612661356 0.380396759556163 14.87709311863932 12.598305121005488 1.746958952072276 0.4128488770716938 4.3075851783952457e-17 0.1064647583825767 0.1545448473936569 4.168446221106459e-07 5.305958966387291e-16 Trans golgi network vesicle budding 12 37 2.8667009318927232 0.0041477476669917 10.53640776699029 36.62378640776699 0.049458611821428 0.5755399655007756 4.812618396852807 3.083264760841391 1.1838693038940356 0.3533924794481698 9.22287925594324e-05 0.0043748091677711 0.0005115527825537 0.0002471633761616 2.258666281935264e-05 Rab geranylgeranylation 14 18 2.849092241587196 0.0043844166861044 7.703883495145631 20.33009708737864 0.0425571144344789 0.6104117024455028 4.535157640190479 2.923418498732157 0.9174138709438756 0.3132937075649342 0.1743595432330578 1.0 1.0 0.7349303615645701 0.0457670040656382 Cargo recognition for clathrin mediated endocytosis 13 34 2.818370214481606 0.0048268120284227 8.473300970873787 32.9126213592233 0.0802035091430913 0.5538966462673686 4.054455271697202 4.1286514785567014 1.088296749159732 0.3439390512580828 2.455399956807989e-06 0.0539251864958397 0.1724639155075248 0.000574878823084 1.9600289467223417e-05 Cell surface interactions at the vascular wall 9 16 2.80285422430059 0.0050652558484634 4.95873786407767 15.691747572815531 0.5051863749151446 0.4839549723278067 2.507415479651395 2.585363930808798 0.9576767064205626 0.3154426595544552 0.0070970061158242 1.0 1.0 0.0068401475593005 0.006476918487605 Intra golgi and retrograde golgi to er traffic 33 89 2.712439219735556 0.0066790028776517 23.762135922330096 91.83252427184466 0.7836914286379623 0.5449079285432085 8.961715947260837 10.213669235838784 1.1120768516172963 0.4008074869702365 4.287536326407647e-05 0.0109309682074606 0.0965212586027388 0.0045446840158695 6.363963400527423e-05 Plasma lipoprotein assembly remodeling and clearance 11 20 2.646084940744717 0.0081429366582064 3.495145631067961 16.83495145631068 -0.156267225907303 0.3789468896930614 2.0090754595317124 2.280551318877052 1.3521243953392292 0.296420660396241 2.4040101743721253e-05 0.1755724648168266 0.3209553841799009 0.0155108289838298 9.884573920484636e-05 Transport of inorganic cations anions and amino acids oligopeptides 8 12 2.64203581057292 0.0082409342073555 3.45873786407767 9.99514563106796 1.347451847228265 0.1988162564497566 2.1544143797408783 1.7967002462592632 1.0339867286779445 0.2465647399589519 5.397781717796104e-05 1.0 0.3467918934582977 0.0901467992310857 0.0002155385692345 Death receptor signalling 4 26 2.554635928488877 0.0106298916418068 5.645631067961165 23.54126213592233 -0.1102863609457894 0.6465088441574995 3.539054689729852 5.442171393384637 0.8141573628490125 0.3087559956450991 0.5388434953655143 0.1131277718078383 0.1086360389997802 0.1660809858489837 0.6989088546616515 Heparan sulfate heparin hs gag metabolism 4 6 2.524953772025041 0.011571350951542 2.4320388349514563 4.83252427184466 0.8003221575390526 0.2230961855611341 1.2648123228701085 1.2708877857521428 1.4628061886044337 0.2633127679646707 0.0086829766575463 0.1430638950507344 0.0376249374527164 0.0009447024772989 0.0179733508374719 Golgi associated vesicle biogenesis 8 29 2.499463077618905 0.0124381659628698 8.759708737864077 29.70145631067961 0.0117084357140251 0.6100432040453254 4.8544872558395 2.3659596085838968 0.9746782938929878 0.3312452125247998 0.006435787265323 0.0285808600856777 0.0157478410048603 0.0104048104957299 0.0012031940780095 Keratan sulfate keratin metabolism 4 5 2.3820332336802346 0.0172173435471385 3.1359223300970873 5.439320388349515 0.1148000450757159 0.1857420338858874 1.294488268568909 0.7592200419566036 1.8452752770630356 0.2520366769461069 0.0004396452857286 1.0 0.0113213926532688 3.906142953800441e-05 0.0010053263520343 Stimuli sensing channels 4 9 2.3795046324231395 0.0173359251198075 3.075242718446602 8.648058252427184 0.6737384899082146 0.3285895756392196 1.7754169999219978 1.9694070657894505 1.2463928142905627 0.307032431313504 0.017765427736657 0.1675604235637086 0.3076603852203092 0.063688713570506 0.0353817250131281 Ion channel transport 14 26 2.3784457211338177 0.0173857963353225 9.031553398058252 27.74271844660194 0.8980727715308076 0.3472480807052641 4.2752930421976005 3.4432740668393595 1.4212023690700646 0.3452897078102002 2.285855094890736e-05 0.3274019772455256 0.5484830827387088 0.0008042937222718 7.80218620903672e-06 Tnf signaling 1 9 2.344166505038374 0.0190696560421688 2.483009708737864 7.453883495145631 -0.1605863100031888 0.5145933999381181 1.812095999809916 2.782628056181418 0.9651354531750088 0.3033674958721901 0.4727418979839556 0.1715759324473242 0.3143397790261298 0.2436114581565515 0.5711827040853724 Mitophagy 3 11 2.342370093218379 0.0191617033454838 3.662621359223301 11.783980582524272 1.3564301304992197 0.1917930287367771 1.8155907654273165 1.3363606860118669 1.2723890100166135 0.2636913304405313 0.0148145229851571 0.0001966568602221 0.0015052123544451 0.0024379570615939 0.0052134507581354 Pink1 prkn mediated mitophagy 3 8 2.3304843003025786 0.0197805688459686 3.2815533980582523 8.473300970873787 1.395617281862234 0.1554977461962819 1.6230588150315317 0.9738153254376878 1.3577427922485954 0.2414588001366878 0.0041482574964162 6.765318543664244e-05 0.0005309775927247 0.00062382482254 0.0010053263520343 Plasma lipoprotein clearance 6 16 2.3230546674345542 0.0201762158492737 2.8980582524271843 13.347087378640778 -0.2018368930286127 0.3332067151933208 1.7692892864455283 1.6527165816198162 1.437154699054494 0.2826032943885157 2.372098591585584e-05 0.1049896535105009 0.1993869387044997 0.0020705519968491 7.568702219565374e-05 Regulation of tnfr1 signaling 1 7 2.322539540135353 0.0202039019236397 1.8519417475728157 5.308252427184466 -0.1481549369001089 0.5006984721896415 1.5547987465385102 2.243573314566278 1.0080178191740088 0.2991677663727714 0.3593880565727997 0.1389130578490434 0.2590666885683055 0.1724444479617574 0.4482773855235765 Sphingolipid de novo biosynthesis 5 10 2.282222523224599 0.0224762059938359 4.08252427184466 10.614077669902912 1.3205451179619188 0.2079933246203462 1.939118365602947 1.3614298144224892 1.289169434780902 0.261809046515659 0.0056546641425135 1.0 0.2445730022705269 0.1552222190730896 0.0023211498250519 Rac2 gtpase cycle 14 33 2.266519261790439 0.0234196091782377 8.905339805825243 34.74757281553398 0.8419178475366841 0.4471774138928159 4.131135699306596 3.707034631516275 0.9898490308362274 0.3561406142763811 0.0003965025521504 0.0576595399457578 0.1827953867238 0.0136037852653257 0.0004978062317691 Immunoregulatory interactions between a lymphoid and a non lymphoid cell 5 7 2.1635416786070425 0.0304995417008429 2.4441747572815533 5.640776699029126 0.4367607020315134 0.3723162326956727 1.3914754509602176 1.0870318448371576 1.21665608087566 0.3078849576437732 0.0195634506709255 1.0 1.0 0.0242110622206542 0.0074494564855197 Mitochondrial protein import 8 34 2.158760492573839 0.0308687529809377 13.468446601941748 34.5873786407767 1.6025718162972953 0.1874419874946837 6.078090089851624 2.2108812815475147 1.8878681708577505 0.2901223460226844 0.0005590165980303 8.566885380985011e-06 0.0002457945313068 1.0845222485789932e-05 0.0001061774836938 Gpcr ligand binding 4 9 2.1559951626468226 0.0310840428817211 3.4611650485436893 9.330097087378642 1.051447004644797 0.2131328881138611 1.5951828582954857 1.3192992367203638 1.3003237502897853 0.2397874119507845 0.0373709737660068 0.0204708743585679 0.0720571885403784 0.0247625444605767 0.0707827064406983 Clathrin mediated endocytosis 15 56 2.155437887730876 0.0311275842077021 13.347087378640778 54.61165048543689 -0.1902727778750813 0.6211571238833282 6.558431633951774 5.961418039601661 0.9253143323693156 0.3262498062687709 2.2910637981964108e-05 0.1115719060554689 0.317502679856318 0.0023720934204197 0.000195788501881 Antigen presentation folding assembly and peptide loading of class i mhc 6 15 2.135050989474599 0.0327568453520257 4.368932038834951 15.359223300970871 0.4885439583196688 0.552320665891318 2.1553288725341515 1.853123151913033 0.7873077885530996 0.3087027768162914 0.0003077778908145 1.0 1.0 0.0195244436529747 0.0001024209024739 Synaptic adhesion like molecules 3 7 2.1330126248595915 0.0329236905612431 1.6674757281553398 5.951456310679611 1.045730316736721 0.2890276876766184 1.4188777313077996 1.1438195320406324 0.8614150619700692 0.2468687149363868 0.0085378879713771 0.0516364610584135 0.1008375048293403 0.027832231049335 0.0013781701696679 Binding and uptake of ligands by scavenger receptors 3 9 2.1245225336070743 0.0336264738504255 1.6286407766990292 7.286407766990291 0.4072923013026871 0.3929582954559311 1.6430066853321073 0.8979532869647183 1.127021484187218 0.2797911593020417 0.0041482574964162 1.0 1.0 0.0074273483269255 0.0078812527225172 Mitochondrial calcium ion transport 5 15 2.1223919530960296 0.0338048373750501 6.502427184466019 16.12135922330097 1.0650233237312683 0.2089377868120644 3.410790121717641 1.246287729205551 1.626144580445205 0.28031724173526 0.00917939970768 1.0 1.0 0.090818300458346 0.0003689915939861 Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 3 11 2.07570086410296 0.0379216259840724 2.342233009708738 10.851941747572816 0.4093935303592591 0.5118730029355861 2.0859825428338192 2.5513980779067897 0.8583599781783465 0.2979240057989124 0.0889016456319048 0.1835089509173778 0.3339976348230559 0.2707185745648809 0.1451121707049519 Rhoa gtpase cycle 14 46 2.0745038573021537 0.0380325408937787 11.383495145631068 46.157766990291265 0.7285935948010234 0.4866370775942555 5.135874153241841 5.803151375541917 0.959659542192298 0.3649179877597411 0.0030215583338199 0.1354750356227081 0.3700525131557232 0.0161335998015439 0.0021062495932256 Metabolism of fat soluble vitamins 6 7 2.0740425870762857 0.0380753558729074 1.6650485436893203 4.580097087378641 0.3536798037155611 0.3331745511018804 1.178052427490116 1.3130753903966457 1.3422038796699125 0.2910915635007025 0.0282735799915187 1.0 1.0 0.0049571663496986 0.0119362160344991 Ire1alpha activates chaperones 7 23 2.0702909471576394 0.0384251068330212 6.050970873786408 24.223300970873787 0.9379365742980283 0.4047880585679882 2.6930013625985207 2.1985522104416564 1.0262193137091864 0.3353529084578252 0.00815731977733 0.0188245552589776 0.0666692325567911 0.0901467992310857 0.00110124435718 Rhog gtpase cycle 14 34 2.0690186613910337 0.038544335562217 9.8373786407767 35.66504854368932 0.6614029400837433 0.4973720188279035 4.308521802053122 2.993429981792782 0.9950331841901028 0.3588671909523165 2.432398493335676e-05 0.290515894493261 0.497470817800254 0.0015979936813088 3.1066114222159566e-05 Lysosome vesicle biogenesis 4 15 2.061157677833976 0.0392879996893673 4.155339805825243 14.065533980582524 0.0338045297007374 0.5442845091130821 2.9436694673613903 1.5836165002042342 1.0229669221105775 0.3256487992521382 0.0086829766575463 0.1430638950507344 0.0376249374527164 0.0415700360883472 0.0179733508374719 Diseases of glycosylation 8 18 2.031272662355672 0.0422273429493671 6.359223300970874 19.17718446601942 0.13180823173309 0.3045208720095976 2.4657040544471793 2.991113672999948 1.5111068586159069 0.284004628008759 0.0115004056660911 1.0 0.1656331484196294 0.0023719924306961 0.0109943535003159 Peptide hormone metabolism 4 13 2.0293034004445576 0.042427397182154 4.021844660194175 14.021844660194176 0.5560275504881529 0.5205961274891826 2.4979619838894513 2.4069092486442756 0.8833525414026219 0.3339695456705046 0.0950522892119901 0.187449079081247 0.0640285846884502 0.2797556636969028 0.0558327828623465 P75 ntr receptor mediated signalling 2 17 2.0270470814230683 0.0426575979695316 3.701456310679612 15.682038834951456 -0.0299058777713717 0.6575383124807638 3.016250133767169 3.3360880116976555 0.736249447013267 0.2885137825083352 0.6431230145127514 0.3241278561278478 0.1827953867238 0.3128952059925546 0.7602385831063151 Ovarian tumor domain proteases 0 10 2.017770566901416 0.0436151615927278 3.3009708737864076 8.611650485436893 -0.0545895007385164 0.62605422182602 2.3558848087632325 1.442981068232173 0.7775147818170627 0.2913094692521883 0.7554179000805259 0.151306852499084 0.2802926639431586 0.5661975770404395 0.8163778738551817 Intra golgi traffic 7 13 2.003696302526662 0.0451026025991612 4.424757281553398 13.87135922330097 0.7636302424906817 0.4243971711811651 2.688824171738392 3.845367291797066 0.9598354803720488 0.3140361333882177 0.0889016456319048 1.0 1.0 0.0808776862517318 0.051296284939533 Signaling by erbb4 2 7 2.0023158840678628 0.0452507687292471 2.453883495145631 7.257281553398058 0.4395977843708076 0.5106764734442939 1.5549199917041956 1.4851433811168728 0.8250198774172108 0.2950845076560141 0.1776374851388814 1.0 1.0 0.5870305126491255 0.2535314416198171 Transport of vitamins nucleosides and related molecules 6 8 1.9881454117558848 0.0467956102099333 3.2985436893203883 7.703883495145631 0.5884630304197642 0.3368828823659784 1.766928610360549 0.9135891377639136 1.2550983698791685 0.3076045725047946 0.00917939970768 1.0 0.1837383274168749 0.0135296171343662 0.017002584405276 Integrin cell surface interactions 4 5 1.964149361777372 0.049512773234563 1.633495145631068 4.203883495145631 0.3179111363730327 0.4479127776597527 1.2499104501809644 0.9864049002328192 1.1220147725505705 0.3186356661300093 0.0612241796762722 1.0 1.0 0.0596874537258691 0.1028731839020021