Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size Glycosaminoglycan degradation 0.9228496388706512 2.7378280277947264 0.0061846407359877 0.9764144793748842 0.6617942144649182 7 P54802,P16278,P06865,P07686,P15586,Q9Y251 6 Degradation pathway of sphingolipids including diseases 0.918176921335358 2.7176812004862665 0.0065741147132276 0.9813866256899212 0.6617942144649182 7 P16278,P06865,P06280,Q99519,P17900 5 Sphingolipid metabolism in senescence 0.7860367113959864 2.6080363208706845 0.0091063291357884 0.9960158022295365 0.6916285996335741 11 P04062,P16278,Q06136,Q96G23,O15269,Q16739,Q13510 7 Sphingolipid pathway 0.7681166841316929 2.517807474379978 0.011808784933323 0.9992344788511798 0.6916285996335741 11 P04062,Q96G23,Q8TCT0,Q9NRX5,O95470,O15269,Q16739,Q13510 8 Sphingolipid metabolism integrated pathway 0.8101585878516483 2.5127246345874705 0.0119802806202984 0.9993106655688672 0.6916285996335741 9 Q96G23,Q8TCT0,O95470,O15269,Q16739,P27544,Q13510 7 Sphingolipid metabolism overview 0.8101585878516483 2.5127246345874705 0.0119802806202984 0.9993106655688672 0.6916285996335741 9 Q96G23,Q8TCT0,O95470,O15269,Q16739,P27544,Q13510 7 1q211 copy number variation syndrome 0.7359136683713818 2.2927086563352597 0.0218647838458403 0.9999984116992904 0.6916285996335741 10 Q9Y624,Q96J84,Q16625 3 Mitochondrial complex iv assembly 0.6839113030010858 2.211205061466438 0.0270216400512941 0.9999999347889108 0.6916285996335741 13 P14406,Q7KZN9,Q15526,Q9Y2R0,P13073 5 Metabolism of spingolipids in er and golgi apparatus 0.8513779527558962 2.056782572530976 0.0397071451874799 0.9999999999764584 0.6916285996335741 5 O95470,Q10472,Q8TCT0,Q16739 4 Calcium regulation in cardiac cells 0.5594672463939526 1.9909049958768896 0.0464913328711149 0.9999999999996748 0.6916285996335741 21 P10644,P54709,P17612,P62942,P16615,P04899,P0DP25,P20020 8 Statin inhibition of cholesterol production 0.7529432768663223 1.97157685524165 0.0486579314789483 0.9999999999999176 0.6916285996335741 7 Q8WTV0,Q07954,P04114,P01130,Q14534 5 Familial hyperlipidemia type 3 0.88356838307641 1.9486147253832744 0.0513414522632305 0.999999999999985 0.6916285996335741 4 Q07954,P98155,P01130 3 Proteoglycan biosynthesis 0.8823911026115598 1.9438521242940396 0.051913285986443 0.9999999999999896 0.6916285996335741 4 Q8TB61,Q9NX62 2 Hippo signaling regulation pathways 0.5742622947644551 1.8850352183498045 0.0594250831327893 1.0 0.6916285996335741 17 P10644,P19022,P17612,P42345,P00533,P08069,P04899 7 Genes controlling nephrogenesis 0.6753140239764424 1.8450522711262227 0.0650299352382175 1.0 0.6916285996335741 9 Q9Y5K6,P05556,Q12948,O94813,Q96J84 5 Complement system in neuronal development and plasticity 0.6285271190288262 1.8349349243814 0.0665153322017713 1.0 0.6916285996335741 12 P15529,P06756,Q5KU26,Q08431 4 Glycerophospholipid biosynthetic pathway 0.7415850803246935 1.8170541231842692 0.0692088264319743 1.0 0.6916285996335741 6 Q9BTU6,O14735 2 Development of ureteric collection system 0.7388664011922723 1.8043912867937328 0.0711699880295513 1.0 0.6916285996335741 6 Q5SZK8,O94813 2 Electron transport chain oxphos system in mitochondria 0.5038438632053917 1.7978697078859232 0.0721976575120817 1.0 0.6916285996335741 50 O14949,P13073,P12235,O75964,P12236,P14406,P05141,O96000,Q9Y6M9,Q7KZN9,P00403,Q9UDW1,O43676,Q15526,P03886,O75438,O95169,P03915 18 Kennedy pathway from sphingolipids 0.7831364829396239 1.7619430999855912 0.0780789115965101 1.0 0.6916285996335741 5 O95470,P35790,Q9UG56,P48651 4 Proximal tubule transport 0.658326133858625 1.7571950399294558 0.0788845704262055 1.0 0.6916285996335741 9 P08195,P04920,P36543,P11166 4 Alzheimers disease and mirna effects 0.3833087008892544 1.7135357707050087 0.086614018414834 1.0 0.6916285996335741 82 P12235,P49721,P12236,P45880,O95197,P16615,Q92542,P60900,Q07954,P21796,Q9Y277,Q9NQC3,P05067,P31751 14 Ferroptosis 0.5179930125711968 1.693192598146867 0.0904188130456642 1.0 0.6916285996335741 22 Q9NZ45,Q96QD8,P02786,P09601,P45880,P08195,P16435,Q9Y277 8 Nonalcoholic fatty liver disease 0.4965094628667714 1.6813972863225664 0.0926857722879215 1.0 0.6916285996335741 47 O14949,O95169,P14406,O96000,Q9Y6M9,P00403,Q9P0J0,Q86Y39,Q9UDW1,O43676,P31751,Q96J02,O75438,P13073 14 Alzheimers disease 0.3835858807736104 1.6566014271427512 0.0976000836388382 1.0 0.6916285996335741 81 P12235,P49721,P12236,P45880,O95197,P16615,Q92542,P60900,Q07954,P21796,Q9Y277,Q9NQC3,P05067,P31751 14 Ebola virus infection in host 0.4966134963692284 1.6523165858379032 0.0984700299248744 1.0 0.6916285996335741 45 P20339,O75569,P61916,O15118,P10321,P06756,P01889,P04439,P05556,Q07021,P00533,Q08431,P51149,P07858,P51151 15 Oxidation by cytochrome p450 0.8091177435224507 1.6435493097303682 0.1002693319178882 1.0 0.6916285996335741 4 P16435,O43169,Q16850 3 Copper homeostasis 0.6599297436731786 1.6405784883398211 0.1008849434303271 1.0 0.6916285996335741 8 P05067 1 Endothelin pathways 0.656411329159041 1.6227570606422237 0.1046413481888117 1.0 0.6916285996335741 8 P16615,P42892 2 Insulin signaling in adipocytes diabetic condition 0.7492928052531338 1.6127360987528714 0.1068018542966657 1.0 0.6916285996335741 5 P14672,P31751 2 Insulin signaling in adipocytes normal condition 0.7492928052531338 1.6127360987528714 0.1068018542966657 1.0 0.6916285996335741 5 P14672,P31751 2 Neural crest cell migration in cancer 0.6517443829891443 1.5990730993446156 0.1098043611090613 1.0 0.6916285996335741 8 Q99523 1 S1p receptor signal transduction 0.6252986821495262 1.5841095954509734 0.1131687811730453 1.0 0.6916285996335741 9 Q9H0H5,P04899,Q13510,P31751 4 Familial hyperlipidemia type 4 0.7898329665405838 1.5633758281032788 0.117964222193414 1.0 0.7097470748214686 4 Q07954 1 Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.6432248177332794 1.555708005918485 0.1197775419701223 1.0 0.7097470748214686 8 P20339,P51148,P61020,P31943 4 P53 transcriptional gene network 0.642119144404633 1.550067999929637 0.1211251956570207 1.0 0.7097470748214686 8 P04066 1 Complement system 0.5659314890753475 1.5307217734671954 0.1258381701586266 1.0 0.7097470748214686 13 P98164,P17612,Q07021,P08754,P15529,P04899,P07942 7 Vitamin b12 metabolism 0.6130989027182362 1.5194538375559516 0.1286482992342308 1.0 0.7097470748214686 9 P04114,P01130,P98164 3 Allograft rejection 0.5874623004181045 1.5043361654764025 0.1324948315288572 1.0 0.7097470748214686 10 P04439,P10321 2 Lipid particles composition 0.938708620124549 1.4981185116764326 0.1341024623229889 1.0 0.7097470748214686 2 P04114 1 Regulatory circuits of the stat3 signaling pathway 0.5851465852376309 1.4915100646507342 0.1358276307743833 1.0 0.7097470748214686 10 P15260,P42345,P00533 3 Camkk2 pathway 0.5848159408305514 1.4896775478452744 0.1363090408597522 1.0 0.7097470748214686 10 P42345,O76024,Q13501,P09601 4 Transcription factors regulate mirnas related to cardiac hypertrophy 0.759425786471756 1.4362101105385046 0.1509425629142229 1.0 0.7397442663362056 4 P31751 1 Overlap between signal transduction pathways contributing to lmna laminopathies 0.5397771116460306 1.4321194607798964 0.1521096358975431 1.0 0.7397442663362056 14 O60725,P42167,P55209,O75844 4 Familial hyperlipidemia type 2 0.8580288061333038 1.4188394548177132 0.1559458270282609 1.0 0.7397442663362056 3 P04114 1 Ccl18 signaling pathway 0.5704241158759769 1.4096393943181116 0.1586461885456527 1.0 0.7397442663362056 10 Q86UE4,P11166,P19022,P00403 4 Small cell lung cancer 0.5257986290956892 1.4093117213315165 0.1587430144046187 1.0 0.7397442663362056 15 P07942,P06756,P31751 3 Metabolic pathway of ldl hdl and tg including diseases 0.7394609198560657 1.3523280642963025 0.1762703904226916 1.0 0.7430209417992328 4 P04114,P01130 2 Immune response to tuberculosis 0.8401551283680877 1.3475341404289558 0.1778082655855253 1.0 0.7430209417992328 3 P15260 1 Head and neck squamous cell carcinoma 0.5134489341173961 1.3300495135735733 0.1835019581336749 1.0 0.7430209417992328 15 P62942,P42345,P00533,P08069,P49815,P31751 6 Familial hyperlipidemia type 1 0.8350904281212077 1.3273288336239877 0.1843999298153491 1.0 0.7430209417992328 3 Q07954 1 Familial hyperlipidemia type 5 0.8350904281212077 1.3273288336239877 0.1843999298153491 1.0 0.7430209417992328 3 Q07954 1 Relationship between inflammation cox2 and egfr 0.6385190287778142 1.3269504674669617 0.184525068327624 1.0 0.7430209417992328 6 P31751 1 Ranklrank signaling pathway 0.4994101881029774 1.3072461676013545 0.1911291204825276 1.0 0.7437856270126948 16 Q13501 1 Cholesterol biosynthesis with skeletal dysplasias 0.6795623532404351 1.3004024335365096 0.1934630763112617 1.0 0.7437856270126948 5 Q15392,Q14739,Q16850 3 Glycerolipids and glycerophospholipids 0.6776826983658406 1.2919166802234037 0.1963860005468354 1.0 0.7437856270126948 5 Q9UG56,P48651,O14735 3 Type ii diabetes mellitus 0.6298203736793333 1.2848060451820502 0.1988600693733997 1.0 0.7437856270126948 6 P14672,Q15526 2 Adipogenesis 0.5045191179785312 1.272466845736696 0.2032072966619686 1.0 0.7437856270126948 15 Q9NZ45,O75844,P43490 3 Autosomal recessive osteopetrosis pathways 0.8209917851830573 1.271106049485221 0.2036909234921256 1.0 0.7437856270126948 3 P51798 1 Familial partial lipodystrophy fpld 0.6073300406491229 1.2611220613437042 0.2072648733080109 1.0 0.7437856270126948 7 O75844,P31751 2 Mitochondrial complex iii assembly 0.5850144703106582 1.2554528406288192 0.2093144175389416 1.0 0.7437856270126948 8 O14949,Q6DKK2,Q9UDW1 3 Extracellular vesiclemediated signaling in recipient cells 0.6035507175631032 1.2421753192066889 0.2141718837247002 1.0 0.7437856270126948 7 Q08431,P00533 2 Network map of sarscov2 signaling pathway 0.4583362302617132 1.2385807448838029 0.2155008025285125 1.0 0.7437856270126948 26 Q08380,O95067,Q07021,P42345,Q96B36,Q96J02,P07858,Q7Z434 8 Orexin receptor pathway 0.4859941894642937 1.2177381948484158 0.2233234776172958 1.0 0.7577942723643073 16 P11166,P01130,P14672 3 Monoamine transport 0.8049180327868792 1.2070922262794723 0.2273966283166006 1.0 0.7630420194623712 3 Q92692,O15127 2 Zinc homeostasis 0.8666011143887418 1.2004142039708166 0.2299785151499094 1.0 0.7674421168538414 2 Q8NEW0 1 Vitamin d metabolism 0.8006894330937309 1.1902751825189506 0.2339382517429451 1.0 0.772124065861961 3 P38435 1 Amyotrophic lateral sclerosis als 0.5289384498535694 1.176297985518618 0.2394758204934088 1.0 0.7796091473946298 10 P07196,P20339,Q9BUN8 3 Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.6973208791845166 1.174791070189934 0.2400783136016575 1.0 0.7796091473946298 4 P09601 1 Nrp1triggered signaling pathways in pancreatic cancer 0.4959642296740347 1.1579859569973974 0.2468697672364028 1.0 0.7875121052336689 14 P31751,P00533 2 Myometrial relaxation and contraction pathways 0.4756285753644302 1.1482853019100034 0.2508508047543074 1.0 0.787815837654049 16 P10644,P16615,P0DP25 3 Mrna protein and metabolite inducation pathway by cyclosporin a 0.7872131147541015 1.1367699650013787 0.2556344622912943 1.0 0.7882397146984421 3 P08195,Q15758 2 Inclusion body myositis 0.7851465342198681 1.1285791732389714 0.259075400488745 1.0 0.7903108176525352 3 P05067 1 Hippomerlin signaling dysregulation 0.4350402297538417 1.0804863097418058 0.2799256799146103 1.0 0.812341361573203 21 P10644,P06756,P19022,P17612,P05556,P00533,P08069 7 Wnt signaling pathway 0.4969924873227971 1.0672949403098135 0.2858386721634638 1.0 0.8146163662634162 12 Q9BTU6,P49815,P42345 3 Nephrotic syndrome 0.4815769540533402 1.0671038361829996 0.2859249497480864 1.0 0.8146163662634162 14 O75844,Q14108,O00592 3 Omega3 omega6 fatty acid synthesis 0.6272965879265022 1.0640167130697709 0.2873211284102055 1.0 0.8147509932383292 5 Q15067,O95864,O95573,O60488 4 Vitamin a and carotenoid metabolism 0.7609574177186791 1.0330777274560137 0.3015675254466354 1.0 0.8393861076947825 3 Q8WTV0 1 Apoptosisrelated network due to altered notch3 in ovarian cancer 0.4556307869512864 1.0137750687805855 0.3106900942233181 1.0 0.8432257133518335 16 Q13501 1 Dopamine metabolism 0.8203867584398705 1.0127966563513948 0.311157298140877 1.0 0.8432257133518335 2 P21964 1 Embryonic stem cell pluripotency pathways 0.483413889967942 0.9860121632536571 0.3241271441882483 1.0 0.8521261494820475 12 P31751,P00533 2 7oxoc and 7betahc pathways 0.5309054057927108 0.9723822212769294 0.3308604332896636 1.0 0.8613780245989519 8 O15118 1 Spinal cord injury 0.4207072167160914 0.9660009530929556 0.3340437041181634 1.0 0.8622324670400457 22 O94813,Q08722,Q9NQC3 3 Hedgehog signaling pathway wp4249 0.6445023201972949 0.9530922895584072 0.3405433124307218 1.0 0.8684453744543471 4 P98164,P17612 2 Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.7377049180327601 0.942138889644895 0.3461215361003895 1.0 0.8684453744543471 3 Q14145,P09601 2 Influence of laminopathies on wnt signaling 0.4855246799328952 0.9295403282361092 0.3526091355163947 1.0 0.8701916451364852 10 O60725,O75844,P14672 3 Metapathway biotransformation phase i and ii 0.4149918931635254 0.9288340644136708 0.3529750878450974 1.0 0.8701916451364852 21 P21964,Q16850,O15217,Q7LGA3,Q86UY6 5 Endometrial cancer 0.4635856002098338 0.90702534973203 0.364393392055087 1.0 0.8910672421104153 13 P31751 1 Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.5158133572125382 0.8933749025246317 0.3716564382359735 1.0 0.9051632608650324 8 P08069,P05556,P42345 3 Oxidative phosphorylation 0.4146356933114568 0.8884871296880261 0.3742787758823831 1.0 0.9078890788472266 30 O75787,O75964,O96000,Q9Y6M9,Q15904,Q86Y39,P03886,O75438,P03915 9 Hair follicle development cytodifferentiation part 3 of 3 0.6277043371624207 0.8833133185550849 0.3770670097800228 1.0 0.9097792906823498 4 Q02487,P00533 2 Vasopressinregulated water reabsorption 0.451352975402945 0.8756999956087071 0.3811931477460342 1.0 0.9097792906823498 14 P20339,P51148,P61020,Q13561 4 Purinergic signaling 0.719016393442611 0.869900451697827 0.3843548086015129 1.0 0.9097792906823498 3 P04899,P08754 2 Nucleotidebinding oligomerization domain nod pathway 0.5109779133660078 0.8681057176141896 0.3853364613027308 1.0 0.9097792906823498 8 Q13685 1 Cannabinoid receptor signaling 0.6207393925503735 0.8545503608352751 0.3928001180822651 1.0 0.9118595569725294 4 P10644 1 Type ii interferon signaling ifng 0.5077829158807411 0.8514261716591275 0.3945326585871989 1.0 0.9118595569725294 8 Q03518,P15260 2 Nanomaterial induced apoptosis 0.5354195283284036 0.825761183199195 0.4089395774947046 1.0 0.9199072000468294 6 O95831 1 Angiopoietinlike protein 8 regulatory pathway 0.4003112148078476 0.7802450233622523 0.4352466657380205 1.0 0.9228956332562892 28 O75955,P42345,P14672,Q14254,P11166,P49815,O14654,P31751 8 Neuroinflammation 0.6889889702736267 0.7559870286995404 0.4496569728149744 1.0 0.936526936483602 3 P00403 1 Target of rapamycin tor signaling 0.4508702388887594 0.7329660626285499 0.4635791285605084 1.0 0.9409149444260896 10 P62942,Q9HB90,P49815,P42345 4 Splicing factor nova regulated synaptic proteins 0.4206864855705903 0.7268377303707421 0.4673253667143879 1.0 0.9409149444260896 15 Q9UNS2,P19022,Q06481 3 Vitamin d receptor pathway 0.4273717256649001 0.7243844513195657 0.4688297429019892 1.0 0.9409149444260896 14 P14672,Q96KA5,P48960 3 Insulin signaling 0.3903922228744368 0.7001605715624324 0.4838270318780928 1.0 0.9409149444260896 41 P10586,Q9H4M9,O75955,P42345,P14672,Q14254,P08069,P11166,O14654,P31751 10 Follicle stimulating hormone fsh signaling pathway 0.4948866998953752 0.6973932281010153 0.485556738354038 1.0 0.9409149444260896 7 P17612,P42345 2 Pi3kaktmtor signaling pathway and therapeutic opportunities 0.6670047736970617 0.6747744643745531 0.499819066384298 1.0 0.9499100632703243 3 P42345 1 Gastric cancer network 2 0.41255714903757 0.6743037630662891 0.5001182121191443 1.0 0.9499100632703243 15 Q86UE4,P00533 2 Primary focal segmental glomerulosclerosis fsgs 0.3811708965031605 0.6659832841332403 0.5054217849068812 1.0 0.9515767981985478 22 O00592,P06756,P19022,Q14108 4 Physiological and pathological hypertrophy of the heart 0.5008204791598372 0.6603777479614789 0.5090114482685744 1.0 0.9515767981985478 6 P63000,P61586,P40763,Q9P2K5,Q08209 5 Arrhythmogenic right ventricular cardiomyopathy 0.4163988901350233 0.6556894793212164 0.5120239394280266 1.0 0.9515767981985478 14 P06756,P19022,P16615,P05556,Q14126,P50402 6 Striated muscle contraction pathway 0.5687590181174207 0.644592859437771 0.5191910634556742 1.0 0.9591901713875792 4 P28289,P08670 2 Thyroid hormones production and peripheral downstream signaling effects 0.4029823151051108 0.6128032625980033 0.540006433335245 1.0 0.9745816132184064 15 P06756,P49815,P17612,P42345 4 Micrornas in cardiomyocyte hypertrophy 0.3701353164162613 0.5997689258831905 0.5486602453364609 1.0 0.9745816132184064 20 P08069,Q9P2K5,P42345,P31751 4 Mitochondrial complex i assembly model oxphos system 0.3744673816208842 0.5948121636939542 0.5519690359019647 1.0 0.9745816132184064 25 O96000,Q9Y6M9,Q9P0J0,O43676,P03886,O75438,O95169,P03915 8 Leukocyteintrinsic hippo pathway functions 0.5173884514435773 0.578216298729118 0.5631180961677269 1.0 0.9745816132184064 5 P63000,P51153,Q13043,P27348 4 Synaptic vesicle pathway 0.4020280844731249 0.5665865162205455 0.5709951380529663 1.0 0.9745816132184064 14 Q13277,P12235,Q96CW1,O00429 4 Nrf2 pathway 0.3649342232392136 0.5445324505934248 0.5860751240466306 1.0 0.9778712014479696 22 Q13501,P09601,P14672,P11166,O15217,Q15043 6 Vitamin dsensitive calcium signaling in depression 0.505365859833272 0.5278895834807134 0.5975759749041305 1.0 0.9795110961471052 5 P20020 1 Ectoderm differentiation 0.3559297274620254 0.5049660326626888 0.6135826936086022 1.0 0.9795110961471052 19 P16278,O00592 2 Sarscov2 and covid19 pathway 0.5310146585137632 0.5000457886811278 0.6170428366070861 1.0 0.9795110961471052 4 O14786,Q8WTV0 2 Estrogen signaling pathway 0.4627502461437448 0.484442294558248 0.6280720082938851 1.0 0.9795110961471052 6 P17612,Q02750,P31749,P28482,O14920 5 Malignant pleural mesothelioma 0.3321004077669397 0.469526947671158 0.638693027670822 1.0 0.9795110961471052 67 P06756,P19022,P08195,P05556,Q08722,Q07820,P42345,P00533,P08069,Q02487,O00592,P11166,P31751,P07942,Q14574 15 Regulation of apoptosis by parathyroid hormonerelated protein 0.4589665209846126 0.46746324454812 0.6401684830633649 1.0 0.9795110961471052 6 Q9BXK5 1 Omega9 fatty acid synthesis 0.4509353462422059 0.4318018136138448 0.6658854612826275 1.0 0.9795110961471052 6 O95573,O00767,O95864,P33121,O60488 5 Nanoparticlemediated activation of receptor signaling 0.4248824452452148 0.4309071454308271 0.6665358877042165 1.0 0.9795110961471052 8 P00533 1 Dna damage response only atm dependent 0.3609683825609417 0.4303026208213859 0.6669755208993886 1.0 0.9795110961471052 17 P01130 1 Eicosanoid synthesis 0.6601114388725193 0.428923461857923 0.6679789254484452 1.0 0.9795110961471052 2 P09960 1 Tyrobp causal network in microglia 0.5104248906744155 0.4253082502419359 0.6706119800484138 1.0 0.9795110961471052 4 P61916 1 Folate metabolism 0.3715481087438639 0.4153665728829376 0.6778735731614072 1.0 0.9795110961471052 15 P04114,P01130,Q8WTV0 3 Hepatitis b infection 0.3500264749426656 0.4114750317485565 0.6807242458627387 1.0 0.979885561722635 25 Q15904,Q9Y277 2 Nonsmall cell lung cancer 0.3747695787565608 0.4017482203601388 0.6878693328292029 1.0 0.979885561722635 14 P31751 1 Drug induction of bile acid pathway 0.6506063585709783 0.4001402204063146 0.6890532416985582 1.0 0.979885561722635 2 Q06520 1 Nuclear receptors in lipid metabolism and toxicity 0.6506063585709538 0.4001402204062425 0.6890532416986113 1.0 0.979885561722635 2 P28288 1 Tgfbeta signaling pathway 0.3526001031469378 0.3886091568297575 0.6975652920302775 1.0 0.9890362356485624 33 Q96J02,P05556,P05067,Q96PU5 4 Complement and coagulation cascades 0.5766120770818973 0.3713916788335088 0.7103458224366339 1.0 0.992054765907683 3 P15529 1 H19 action rbe2f1 signaling and cdkbetacatenin activity 0.4359234183571067 0.3666808041340195 0.7138571267818459 1.0 0.992054765907683 6 Q16527 1 Notch signaling pathway 0.3799045277419427 0.3608554738836996 0.7182074906272369 1.0 0.992054765907683 11 Q92542 1 Arachidonate epoxygenase epoxide hydrolase 0.6368403802032219 0.3601220350532738 0.7187558751675762 1.0 0.992054765907683 2 P34913 1 Glycosylation and related congenital defects 0.3818707753348827 0.3562914876598813 0.721622283483047 1.0 0.9928470597352174 10 Q9BV10,Q9BT22,Q9Y5P6,Q2TAA5,Q9H0U3 5 Neuroinflammation and glutamatergic signaling 0.3369726102519064 0.3244471348885355 0.7455995395115056 1.0 1.0 24 P09622,P15260,P11166 3 T cell receptor and costimulatory signaling 0.4804854050508339 0.3233576313339398 0.7464244126831407 1.0 1.0 4 P49840,Q08209,P48729 3 Progeriaassociated lipodystrophy 0.3857386617413525 0.3085895559697726 0.7576337665040913 1.0 1.0 9 O75844 1 Triacylglyceride synthesis 0.5544262295081933 0.3073925559349643 0.7585445935994215 1.0 1.0 3 O00116,Q99943 2 Hair follicle development organogenesis part 2 of 3 0.5499303727562399 0.2950535298314504 0.7679529879973175 1.0 1.0 3 P05556 1 Focal adhesion pi3kaktmtorsignaling pathway 0.3402265320533773 0.2783080809453814 0.7807758733778933 1.0 1.0 41 P06756,P05556,P14672,P42345,P08069,P00533,P11166,P61019,O14654,P07942,P31751 11 Caloric restriction and aging 0.4402050504237926 0.2756438521609506 0.7828216247892004 1.0 1.0 5 P43490 1 Selenium micronutrient network 0.3604127596214891 0.2744908835278578 0.7837074085717128 1.0 1.0 12 P04114,P01130 2 G protein signaling pathways 0.346489942589683 0.2658576609305184 0.7903488336004645 1.0 1.0 15 P10644,P04899,P17612,P08754 4 Pi3kakt signaling pathway 0.338646738182492 0.265666583053352 0.7904960016270492 1.0 1.0 40 P06756,P05556,Q07820,P42345,P00533,P08069,P07942,P31751 8 Sulfation biotransformation reaction 0.4621187274516081 0.2655092591998454 0.790617177939952 1.0 1.0 4 Q06520,P00390,P11413 3 Ras signaling 0.3356515051886627 0.2635974037033215 0.7920901593364986 1.0 1.0 32 P20339,P17612,P61020,P00533,P0DP25,P51148,P11233,P31751 8 Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition 0.4220266811588908 0.21360837043069 0.8308524713969312 1.0 1.0 5 P19022 1 Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.3920572609366161 0.1911391877703267 0.8484165461835507 1.0 1.0 6 P18031,P00533 2 Phase i biotransformations non p450 0.5039836342390711 0.1824655555033809 0.855217383291438 1.0 1.0 3 P38571 1 Autophagy 0.3883426927235624 0.1775045647369254 0.8591120800266032 1.0 1.0 6 P42345,Q9Y4P8 2 Map3k1 role in promoting and blocking gonadal determination 0.5003278688524566 0.1746295349442683 0.861370739643488 1.0 1.0 3 P35222,P61586 2 Glycogen synthesis and degradation 0.3232527708745475 0.1616602736206255 0.8715733900133025 1.0 1.0 16 P52789,P0DP25 2 Cardiac hypertrophic response 0.3338630177754303 0.1407788615571635 0.8880446427719018 1.0 1.0 12 P31751 1 Mirna regulation of prostate cancer signaling pathways 0.3686802363755685 0.1355441959384514 0.8921816233447202 1.0 1.0 7 P35222,Q02750,P42345,Q8NCF5,P28482,P62993 6 Angiogenesis 0.4803278688524663 0.1348437103130983 0.8927354455852654 1.0 1.0 3 Q05397,P28482 2 Initiation of transcription and translation elongation at the hiv1 ltr 0.3683519369665131 0.1343411460484151 0.8931328182719942 1.0 1.0 7 Q92769,Q08209,P50750,Q13547,P18615,Q8IXH7 6 Thyroid stimulating hormone tsh signaling pathway 0.3060955518945714 0.1248276633623664 0.9006599864806861 1.0 1.0 18 P62753,P11802,Q14344,P27695,P40763,Q14160,Q15418,Q02750,P42345,P08754,P08069,P42224,P04899,P31749,P28482,P24941,P63096 17 Hippoyap signaling pathway 0.5260570304817999 0.122035489177529 0.9028709120124736 1.0 1.0 2 Q13043 1 Bdnftrkb signaling 0.3537116560683669 0.1183131700746827 0.9058195224829004 1.0 1.0 8 P42345 1 Wnt signaling in kidney disease 0.5168797115699667 0.1094538115893897 0.912842554604662 1.0 1.0 2 P35222 1 Serotonin htr1 group and fos pathway 0.3603403680253864 0.1055933482257589 0.91590500259235 1.0 1.0 7 P04899,P08754 2 Mapk and nfkb signaling pathways inhibited by yersinia yopj 0.4622950819672204 0.1034979773258335 0.917567754735088 1.0 1.0 3 O14920,P28482 2 Vitamin d in inflammatory diseases 0.4622950819672203 0.1034979773258332 0.9175677547350882 1.0 1.0 3 O14920,Q08209 2 Thymic stromal lymphopoietin tslp signaling pathway 0.3271550220465017 0.1007036580582285 0.9197857074285424 1.0 1.0 11 Q9BTU6 1 Neural crest differentiation 0.3634301704396601 0.0920639772790255 0.926647208831596 1.0 1.0 6 P19022 1 Somatroph axis gh and its relationship to dietary restriction and aging 0.3875910970595399 0.0770164072738196 0.9386104926180108 1.0 1.0 4 P42345 1 Regucalcin in proximal tubule epithelial kidney cells 0.3516086671043944 0.0756499017497625 0.9396976343236628 1.0 1.0 7 P42574,Q13283,P42345,Q8NE86,P31749,P28482 6 Praderwilli and angelman syndrome 0.3684383202099724 0.0598425330392189 0.952281049791166 1.0 1.0 5 P11802,Q15154,Q7L576,O95714 4 Pregnane x receptor pathway 0.366797900262464 0.05590463609752 0.9554177775363206 1.0 1.0 5 Q06520,P08183,P62195,Q99615 4 Nodlike receptor nlr signaling pathway 0.4621435594886796 0.0551254541135315 0.95603851752279 1.0 1.0 2 O14920 1 Altered glycosylation of muc1 in tumor microenvironment 0.4621435594886796 0.0551254541135315 0.95603851752279 1.0 1.0 2 O14920 1 Ovarian infertility 0.4575549000327634 0.0520109626759746 0.9585199582859096 1.0 1.0 2 P11802 1 Liver x receptor pathway 0.4503441494591832 0.0475044159180791 0.9621112109173172 1.0 1.0 2 O00767 1 Nocgmppkg mediated neuroprotection 0.3664252200282965 0.0388114703040504 0.969040699745692 1.0 1.0 4 P07196,Q13555 2 Benzoapyrene metabolism 0.333988856112743 0.0181993136692253 0.9854798501591562 1.0 1.0 2 P07099 1 Hostpathogen interaction of human coronaviruses apoptosis 0.3512627090849463 0.0157501522713423 0.9874337162218904 1.0 1.0 4 Q07820,P31749,P42574 3 Brainderived neurotrophic factor bdnf signaling pathway 0.3058204790543557 0.0120489925198822 0.9903865275068582 1.0 1.0 42 Q13501,Q99523,Q96P70 3 Srebf and mir33 in cholesterol and lipid homeostasis 0.3318439627028109 0.0006495234232512 0.9994817553251476 1.0 1.0 6 P01130 1