diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..ccbcbe1eccc182592d15b56e9c90a4c2554181cf --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9f0112786cbe4220df388f97486d46fc63e27310ebe592ce4c83d9ad0ff4a20a +size 91795 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2b79c8a98c691d63999ea7388fe681a2d076fcc8 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 54, + "title": "Average number of proteins per term", + "value": 2.925925925925926 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e3b11ec2b327be077a7abc8c39baf6d87140db6a --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9a48e58ba91ee85b9c138dbf59d1e60d53b7679a --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Histidine acid phosphatase active site [IPR033379] 0.9112163361941416 3.774608539685007 0.0001602591211349 0.0086173420717791 0.0004120948829183 2 Q9NPH0 1 +Serine carboxypeptidase, serine active site [IPR018202] 0.928063943161633 3.4914091978951616 0.0004804797541608 0.0256182795111275 0.0010810794468619 3 P10619,Q9HB40 2 +Cysteine peptidase, asparagine active site [IPR025661] 0.8375258952352787 3.415809383287499 0.0006359274485003 0.033767707982858 0.0011841407661731 2 P07858 1 +Cysteine peptidase, histidine active site [IPR025660] 0.8375258952352787 3.415809383287499 0.0006359274485003 0.033767707982858 0.0011841407661731 2 P07858 1 +Tyrosine-protein kinase, active site [IPR008266] 0.5039046824819963 0.7275656328464342 0.4668795247401656 0.9999999999999982 0.5042298867193789 6 P00533,Q15375 2 +Cysteine peptidase, cysteine active site [IPR000169] 0.3242274804786542 0.1150851018273285 0.9083776684574136 1.0 0.9083776684574136 5 P07858 1 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..13404243e8b5d738db396d9909ac03eb23142db6 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EGFR", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LONP2", "LYN", "MAP2K1", "MAP2K4", "MAPK1", "MAPK3", "MARK2", "MARK3", "MDH1", "MDH2", "MTM1", "MTMR2", "MTMR6", "NEK9", "NME1", "NME2", "NME3", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKACA", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK3", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "VRK2", "WNK1", "WNK3", "YES1"], "leading_proteins": ["ACP6", "CTSA", "CTSB", "EGFR", "EPHA7", "SCPEP1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f3b26703d03c02d60d7c3cab91f02c62159068dd --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2f3edf63834fe0a5e071094d61ce969207ccdfb9d472142c9ce862a5a39b913a +size 129005 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..9b5bfa1b38a5d78aee661add66ee54b24fc81273 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ae2284aefa57ecdae5f09bc91a5d717435b418500b1836b00761451b55580eb9 +size 83704 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ca71c519d12a7c9c28c19191a8433fcb4371ada0 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 32, + "title": "Average number of proteins per term", + "value": 4.8125 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d1922971db2ceb3bac6c562d7f2475bf9c91d60f --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..35a8cd4c4cb2ae4b7a5802cd0648114a40dad5c4 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Peptidase M16, zinc-binding site [IPR001431] 0.6633327506371302 1.686605855825602 0.0916791652295807 0.9539046802072472 0.1173493314938633 5 P22695 1 +EF-Hand 1, calcium-binding site [IPR018247] 0.4342020042712126 1.6657396078612288 0.095765289398237 0.9600977327493908 0.1178649715670609 40 Q9NWM8,Q14257,O43852,O95202,O95302,Q9Y680,P80303,Q96D71,P41208 9 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f438b00ccceb97894483e8bcad0a95140f3294d9 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Legume lectin, beta chain, Mn/Ca-binding site [IPR019825]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "AKT2", "APEX1", "APOBEC3C", "ARG2", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EGFR", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LRP2", "LYN", "MACF1", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MARK3", "MCCC1", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDP1", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA1", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK4", "TAOK3", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CALU", "CETN2", "FKBP14", "FKBP7", "FKBP9", "LETM1", "NUCB2", "RCN2", "REPS1", "UQCRC2"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..145d3e094c2aef400b7d961308f40852f8d581eb --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Syntaxin/epimorphin, conserved site [IPR006012]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..55b5d56dbff236570d6889eca070a9743cb6d845 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e7c61e37439bab44793ccbe078f853bcc02a8d3b593d2b7f5f6fbbcb970e200a +size 188603 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..d6cfeb0e6aa7a379b9fe3f412f0a4b44d6ee9c81 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Syntaxin/epimorphin, conserved site [IPR006012]", "1": "Intermediate filament protein, conserved site [IPR018039]", "2": "14-3-3 protein, conserved site [IPR023409]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..fc901f3f4cec900e139499a2422e24cdc5a73351 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:53c97a927b531fc282f3e85668fc5ad869d7b32b42bf043fd8e2c03538bb2959 +size 140703 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..d266536315d05635a7adb8f34d9fbda5b986c0cf --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0857a8f3bac41a59412ea6c527d00648ae0999da3d201b22ee4409914931f0c +size 137274 diff --git a/interpro_conserved_site/basic/plot_2.png b/interpro_conserved_site/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..a3d85df8553f6037d66e3b5de42ff3d00ddff5a8 --- /dev/null +++ b/interpro_conserved_site/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:52689023012a788f116709f2352b27c20cb6327b4e0f111c5be0893fa37b8a57 +size 147926 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..91cafd82073cddd784c741435c6b8a25d78aeef6 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ef61941aa834599164b54667a5b2fc7ade4c6bed4ef1b71f5855d4fc7004cc4c +size 157745 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..92585e6119931e043e4d4d8413fe63b0be003991 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Syntaxin/epimorphin, conserved site [IPR006012] 5 7 2.224055222359276 0.0261447290634726 2.592233009708738 5.847087378640777 0.9961908981999794 0.2839139128702306 1.4759357288864456 1.4239341993278547 1.138258151200134 0.2914162845337057 0.0065763731833925 1.0 0.0067896670197663 0.0033170374819039 0.0002481332774246 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c215033d5575780b6b88f463e604bd14cd34ff3a --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 283, + "title": "Average number of proteins per term", + "value": 2.791519434628975 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9138d80181fd0de1a5dd987baa507e8905159472 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7d42d022b9693ce9fdcda5f35cff9775d75231de --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,38 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tetraspanin, conserved site [IPR018503] 0.9931932524415508 4.155886145014982 3.2402916714247e-05 0.0091282561846006 0.0003229657593592 2 O60637 1 +Haem oxygenase conserved site [IPR018207] 0.9884581237052384 4.134340525064857 3.559753356729978e-05 0.0100237057184999 0.0003229657593592 2 P30519 1 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.9298609055933712 3.8629089509389702 0.000112044776811 0.0312129446533976 0.000570234758197 2 Q9BTY2 1 +Glycoside hydrolase, family 35, conserved site [IPR019801] 0.878958271678012 3.6195142888690848 0.000295156513306 0.0801472009739617 0.0010708883752 2 Q8IW92 1 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.8372299496892588 3.4143355224980856 0.000639377848987 0.1655661447073886 0.0019046729606666 2 P01889 1 +Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728] 0.8245042912104191 3.350700672962252 0.0008060738146637 0.2040436086053851 0.0022364597014691 2 Q07820 1 +Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726] 0.8245042912104191 3.350700672962252 0.0008060738146637 0.2040436086053851 0.0022364597014691 2 Q07820 1 +Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717] 0.8245042912104191 3.350700672962252 0.0008060738146637 0.2040436086053851 0.0022364597014691 2 Q07820 1 +Lysosome-associated membrane glycoprotein, conserved site [IPR018134] 0.8215448357502237 3.335828848130437 0.0008504550412573 0.2139863953422815 0.0023366871521925 2 P11279 1 +S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082] 0.6975436519680418 2.68641779577407 0.0072222717454841 0.8714348431767069 0.0127743931498251 2 O43865 1 +Syntaxin/epimorphin, conserved site [IPR006012] 0.8003042116259121 2.224055222359276 0.0261447290634726 0.9994454756363224 0.0383365716319314 7 Q9P2W9,O15400,Q13190,O60499,O43752 5 +Intermediate filament protein, conserved site [IPR018039] 0.7135668716136672 1.9189046535137235 0.0549964016038293 0.9999998883985572 0.0720554706198319 8 P07196,P07197,Q03252,P08670,P20700 5 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.5870337477797574 1.7668402143455937 0.0772549917896627 0.999999999868743 0.0967396578605069 3 P09429,P26583 2 +Thioredoxin, conserved site [IPR017937] 0.6020714407881019 1.7370770296151825 0.082373575256361 0.9999999999728072 0.1026948096808377 12 O95881,Q9H3N1,Q9H1E5,Q96JJ7 4 +Ribosomal protein L24/L26, conserved site [IPR005825] 0.531222255105066 1.727812117522502 0.084021914194591 0.9999999999836516 0.1042903584081985 2 P61254 1 +Acyl-CoA-binding protein, ACBP, conserved site [IPR022408] 0.5693306546100935 1.66761679612558 0.0953918218459337 0.9999999999995232 0.1173734155756489 3 Q5T8D3 1 +Polyprenyl synthetase, conserved site [IPR033749] 0.5025155371411735 1.5525571184939484 0.1205289769136332 1.0 0.1457679507117872 2 P14324 1 +Histidine triad, conserved site [IPR019808] 0.4957087895827238 1.5106704336568098 0.130872438945913 1.0 0.1576038307306101 2 Q96C86 1 +Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.6165657392515493 1.4537394324587989 0.1460185612404818 1.0 0.1743597165867357 5 P48735 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.4844628588339824 1.441228827558501 0.1495200467613431 1.0 0.1777906438380676 2 P50570 1 +Clathrin adaptor complex, small chain [IPR000804] 0.5227945529899511 1.40321961517455 0.1605513601142192 1.0 0.1885312651963653 3 P61923,Q92572 2 +Cadherin conserved site [IPR020894] 0.5958205583373564 1.3493507345968594 0.1772243368501906 1.0 0.2063970671959011 5 Q14574 1 +Mrp, conserved site [IPR000808] 0.452796685409892 1.2445037434601405 0.2133142224753199 1.0 0.2444045544960143 2 Q8TB37 1 +Guanylate kinase, conserved site [IPR020590] 0.5718099741354987 1.1204242288385686 0.2625330248783444 1.0 0.2948287541292518 7 Q9NZW5,Q8N3R9 2 +Proteasome beta-type subunit, conserved site [IPR016050] 0.5300299926105169 0.984278440277717 0.3249786270691954 1.0 0.3620824860652846 8 P20618,P28072,P28074,P49721 4 +Mini-chromosome maintenance, conserved site [IPR018525] 0.5511173795097929 0.950494527332202 0.3418610333485175 1.0 0.379398715441688 6 Q14566,P33991 2 +Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415] 0.4410894020130244 0.933657963969784 0.3504803551514592 1.0 0.3874450801088397 3 Q07954,P98164 2 +Calreticulin/calnexin, conserved site [IPR018124] 0.4319123741859104 0.8813993006966623 0.3781017360397611 1.0 0.414739501159893 3 P27824,O14967 2 +Heat shock protein Hsp90, conserved site [IPR019805] 0.4215512137359524 0.8227669298898195 0.4106405460006643 1.0 0.4469664404545693 3 P07900,P14625 2 +EGF-like calcium-binding, conserved site [IPR018097] 0.4412200177672381 0.7283939102174816 0.4663724900379082 1.0 0.5037534911478169 4 O94813,Q07954,P98164 3 +Annexin repeat, conserved site [IPR018252] 0.4697631358326972 0.7161584847481479 0.4738934943566915 1.0 0.5079994655414534 5 P20073 1 +Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.4080544862303685 0.5609705784009773 0.5748175943297416 1.0 0.6002707719384386 4 Q8WWV3,Q08257,Q99536 3 +Adenylate kinase, conserved site [IPR033690] 0.4318720379146832 0.5357309951737191 0.5921444789224499 1.0 0.6160914982906373 5 Q9UIJ7,P54819,P00568,P27144 4 +Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.3594334313163412 0.486582801285782 0.6265540140699368 1.0 0.6471342554080004 3 P27361 1 +4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900] 0.3181414619710055 0.437821837091724 0.6615154398203353 1.0 0.678293005323025 2 P21912 1 +DnaJ domain, conserved site [IPR018253] 0.3546671125754954 0.2350111741233596 0.8142000603874835 1.0 0.819995078610882 10 O60884,Q96EY1,Q96KC8,Q9NVH1 4 +14-3-3 protein, conserved site [IPR023409] 0.3333333333333356 0.0716513779866233 0.942879351393718 1.0 0.942879351393718 6 P62258,Q04917,P31946,P61981,P63104 5 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0240c8d30f8f6e80c52580b722c99c36b2fa6a6d --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Disintegrin, conserved site [IPR018358]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AACS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAM9", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BTRC", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CDC40", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCP2", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DUS3L", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FOXK2", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD13", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRP2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MIF", "MKRN2", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF2", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCDH19", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM3", "PHF14", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RECQL5", "REL", "RIDA", "RNF114", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A2", "SLC27A4", "SLC5A6", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ACBD5", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "ANXA7", "AP3S1", "CANX", "CLGN", "COPZ1", "CRYZ", "DCPS", "DNAJA2", "DNAJA3", "DNAJC1", "DNAJC11", "DNM2", "DSC3", "FDPS", "FUCA2", "GLB1L2", "HLA-B", "HMGB1", "HMGB2", "HMOX2", "HSP90AA1", "HSP90B1", "IDH2", "LAMP1", "LMNB1", "LMNB2", "LRP1", "LRP2", 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@@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c4a1452c792564c0a2b8f6bcf17e8aa7185b806c07003b408bd69b3a6da9a2e4 +size 127960 diff --git a/interpro_domain/basic/plot_8.png b/interpro_domain/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..1012a61fec4bbbe0122fbcac591633bf83e1d195 --- /dev/null +++ b/interpro_domain/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6c6553f6614bf22428b15fe19ce3845a37fb868f613cecfb078542c6bc19dd7c +size 132655 diff --git a/interpro_domain/basic/plot_9.png b/interpro_domain/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..0b726a777c4334b24736620b930a236528f46ce9 --- /dev/null +++ b/interpro_domain/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2e1919a6e1337525817f2ef227c6c867795aea257363eb186938e8bb79e998cf +size 133407 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..57ca929b57fa340bd9aeecc651025c921ba3b980 --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1f71f7c265395846d3c61f4e4b0638a31278d681e1444169b9d9298a3789573d +size 985484 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fbcfe1246d997de35fd5dffdacf8d73974a87ce0 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,9 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +RNA recognition motif domain [IPR000504] 47 120 2.4974366780400623 0.0125094804533363 39.713592233009706 116.0 0.2316956716939257 0.5316884276370477 13.873754985119357 5.729331786381952 1.713447249572458 0.3950212299678106 0.007522076530849 1.0 0.8195646169006738 0.0250887792630903 0.0001059935006596 +Zinc finger, RanBP2-type [IPR001876] 4 9 2.294609664777456 0.0217555039000301 3.2742718446601944 8.616504854368932 0.6239078002715212 0.4100405386528319 1.463145369641179 0.7330740021954685 1.0299872364022182 0.3121093098016552 0.0003636238723029 1.0 0.1854358412925483 0.0001164002838048 0.0028394369313259 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 3 5 2.209303478871933 0.0271535393873814 1.5266990291262137 3.325242718446602 0.960965150554702 0.3355014533934438 0.8283600459505593 0.8041420014919527 1.008146449418134 0.2788845881573986 0.2214576049043232 0.0378187125466048 0.075113296023457 0.1775366954381628 0.0053334351931861 +GOLD domain [IPR009038] 5 6 2.1506581055845944 0.0315031953899556 2.8762135922330097 6.247572815533981 0.4192390492462461 0.3068843884052658 1.4199402534298398 0.930533270242389 1.3963570929114475 0.294203492723015 0.3342830117953164 1.0 0.1191939669275513 0.2721697661507766 0.0027834726260547 +Target SNARE coiled-coil homology domain [IPR000727] 5 10 2.138132103184896 0.0325060230459637 3.5024271844660193 8.266990291262136 0.5942034778060385 0.4012381903331891 1.9023475359698396 2.183694577914796 1.0582363712887182 0.3038263160802639 0.1789878690111356 1.0 0.2166826538338764 0.1211421538065826 0.0063149437065281 +L27 domain, C-terminal [IPR014775] 2 5 2.057322430533189 0.0396552211238911 1.6844660194174756 3.7305825242718447 0.5658993396363393 0.4543767507253494 1.1049102482158044 1.0157672744340132 0.9802951934421584 0.315121957589178 1.0 1.0 1.0 1.0 0.3290745839784397 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 3 6 2.006584755689639 0.0447938958400222 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.4978685671145173 1.0 1.0 0.4160065505344545 0.2906426697670494 +Phospholipid/glycerol acyltransferase [IPR002123] 4 5 1.977458461092137 0.0479898314262929 2.4611650485436893 6.109223300970874 0.4541526786138767 0.3733328307275969 1.647577392422315 1.6678607828333205 1.200305691546449 0.3080828121567173 0.3939928003913119 1.0 1.0 0.3236592382947187 0.1812716861639223 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..075405d7570ed29415b2441aa132d61025cd0f90 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 2760, + "title": "Average number of proteins per term", + "value": 2.205797101449275 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..896caa66e9b04a673a3fa8ceb22b870b3396df91 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..37c52c8508f7823b2151d6c7c22f4b05a4241e3e --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,214 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +MENTAL domain [IPR019498] 0.9840189405149452 4.114090076092235 3.8870963980697226e-05 0.1017312198805546 0.0003390041754266 2 O95772 1 +EXPERA domain [IPR033118] 0.9807635395087309 4.099207935302771 4.145664567301033e-05 0.1081191342203453 0.0003488425062729 2 Q15125 1 +BRICHOS domain [IPR007084] 0.944362237348328 3.9309278997994506 8.461864745479275e-05 0.2082878092805101 0.0005406191365167 2 Q9NQX7 1 +Acyl-CoA oxidase, C-terminal [IPR002655] 0.9419946729801724 3.9198616066090968 8.859983161046969e-05 0.2169403220049971 0.0005545023474941 2 O15254 1 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.933708197691625 3.8810104254918114 0.0001040233811211 0.2495779262330891 0.0006018962932795 2 P98179 1 +Syntaxin 6, N-terminal [IPR015260] 0.9301568511393914 3.8643028078108688 0.0001114069480996 0.2647173573813474 0.0006252710063003 2 O43752 1 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.9298609055933712 3.8629089509389702 0.000112044776811 0.2660107599862146 0.0006252710063003 2 Q9BTY2 1 +Phospholipase D/Transphosphatidylase [IPR001736] 0.919206865936669 3.812569669754608 0.0001375294448477 0.3158700349145585 0.0006802531680643 2 Q8IV08 1 +MD-2-related lipid-recognition domain [IPR003172] 0.9097366084640433 3.7675590807623056 0.0001648515342331 0.3655696323616805 0.0007795454458345 2 P17900 1 +Fatty acid hydroxylase [IPR006694] 0.8919798757028712 3.6824813168592607 0.0002309748001783 0.4714215691533372 0.0009644333562664 2 Q15800 1 +Glycoside hydrolase 35, catalytic domain [IPR031330] 0.878958271678012 3.6195142888690848 0.000295156513306 0.5572509829188822 0.0011489872732364 2 Q8IW92 1 +Protein Kinase B, pleckstrin homology domain [IPR039026] 0.8768866528558753 3.609451137931989 0.00030684556345 0.571311064229264 0.0011795477415086 2 P31751 1 +Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.8733353063036422 3.592170606118514 0.0003279350336662 0.5955588868688628 0.0012347894855645 2 Q9Y282 1 +Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.8733353063036422 3.592170606118514 0.0003279350336662 0.5955588868688628 0.0012347894855645 2 Q9Y282 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.872151524119563 3.586402146092756 0.0003352717927862 0.6036688994885755 0.001255563294559 2 O60506 1 +Marvel domain [IPR008253] 0.8620893755548992 3.5372018971977615 0.0004043904064392 0.6725248996425378 0.0014384638487442 2 O43760 1 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.9381290704558922 3.5371710376352663 0.0004044376618208 0.6725676250268993 0.0014384638487442 3 Q15629,P27544 2 +START domain [IPR002913] 0.8588339745486853 3.5212192482186646 0.0004295672812955 0.6945167768851523 0.0014959541726854 2 Q14849 1 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.8564664101805293 3.509575425911525 0.0004488227408609 0.7103346065183698 0.0015369116188292 2 P13674 1 +CARG-binding factor, N-terminal [IPR012956] 0.8546907369044109 3.5008314264767675 0.000463809124602 0.7220767103315802 0.0015767692631447 2 Q99729 1 +Peptidase C1A, papain C-terminal [IPR000668] 0.8375258952352787 3.415809383287499 0.0006359274485003 0.8272168729394015 0.0020220734537569 2 P07858 1 +Ion transporter-like, CBS domain [IPR044751] 0.8357502219591609 3.4069621349070593 0.000656902395256 0.8369415201559783 0.0020673325095857 2 Q8NE01 1 +CNNM, transmembrane domain [IPR002550] 0.8357502219591609 3.4069621349070593 0.000656902395256 0.8369415201559783 0.0020673325095857 2 Q8NE01 1 +FAD linked oxidase, N-terminal [IPR006094] 0.8333826575910049 3.3951505319561024 0.000685908769598 0.8494948161028446 0.0021308821817202 2 Q15392 1 +FAD-binding domain, PCMH-type [IPR016166] 0.8333826575910049 3.3951505319561024 0.000685908769598 0.8494948161028446 0.0021308821817202 2 Q15392 1 +OCRE domain [IPR041591] 0.9062741812003592 3.3914374905273688 0.0006952702100755 0.8533363167018931 0.0021439623872879 3 P98175 1 +Far upstream element-binding protein, C-terminal [IPR015096] 0.8313110387688682 3.3848010224160276 0.0007122986863901 0.8600744630639443 0.002177125553086 2 Q96AE4 1 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.9006415066528335 3.365390638073433 0.0007643536061947 0.8788132591734212 0.0022852895206181 3 Q5HYI7 1 +Metaxin, glutathione S-transferase domain [IPR033468] 0.9006415066528335 3.365390638073433 0.0007643536061947 0.8788132591734212 0.0022852895206181 3 Q5HYI7 1 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8129624149156576 3.2925430535509124 0.0009928569510655 0.93553587694464 0.0027320889181863 2 Q9NVI7 1 +Zinc finger, CHHC-type [IPR012996] 0.8836589698046172 3.286342570350879 0.0010149749094632 0.9393571386564322 0.0027708513848847 3 P31943,P52597 2 +Glycoside hydrolase family 20, catalytic domain [IPR015883] 0.7972773009766232 3.2128220751674084 0.0013143768681074 0.973485573993947 0.0033129499141337 2 P06865 1 +Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019] 0.7972773009766232 3.2128220751674084 0.0013143768681074 0.973485573993947 0.0033129499141337 2 P06865 1 +Tim44-like domain [IPR007379] 0.7931340633323494 3.1916298870767115 0.001414724863634 0.9799074308733008 0.0034894018084271 2 O43615 1 +GMP phosphodiesterase, delta subunit [IPR008015] 0.7916543356022516 3.1840475720210653 0.0014523114244291 0.981890037184748 0.0035789102959146 2 A6NIH7 1 +Legume-like lectin [IPR005052] 0.7818881325836071 3.1338225885305415 0.0017254514339324 0.99148868821401 0.0040567539357599 2 P49257 1 +RBM1CTR [IPR012604] 0.7801124593074902 3.124656681780255 0.001780126904276 0.9926828068053783 0.0041496201484814 2 P38159 1 +Calcium uniporter protein, C-terminal [IPR006769] 0.7795205682154509 3.1215990367196276 0.0017987173644535 0.9930494196357216 0.0041823588255197 2 Q9NWR8 1 +Choline/carnitine acyltransferase domain [IPR039551] 0.7753773305711777 3.100162633875612 0.0019341441033688 0.995220440311542 0.0044190709646507 2 P50416 1 +BAG domain [IPR003103] 0.7703462562888459 3.074055032673328 0.0021117047458996 0.9970750199112216 0.0046870319783144 2 Q9UL15 1 +Reticulon [IPR003388] 0.9076174121753812 3.0696759518874 0.0021429113799458 0.9973168975727064 0.0047429313621896 4 O95197,O75298 2 +MHC class I, alpha chain, C-terminal [IPR010579] 0.8374777975133186 3.0673504806201164 0.0021596547415498 0.997438322184836 0.0047609002289757 3 P10321,P01889 2 +MHC class I-like antigen recognition-like [IPR011161] 0.8374777975133186 3.0673504806201164 0.0021596547415498 0.997438322184836 0.0047609002289757 3 P10321,P01889 2 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.8374777975133186 3.0673504806201164 0.0021596547415498 0.997438322184836 0.0047609002289757 3 P10321,P01889 2 +Immunoglobulin C1-set [IPR003597] 0.8374777975133186 3.0673504806201164 0.0021596547415498 0.997438322184836 0.0047609002289757 3 P10321,P01889 2 +Sam68, tyrosine-rich domain [IPR032335] 0.7647232909144748 3.044774515718151 0.0023285481608448 0.9983944471202072 0.0050209319718216 2 O75525 1 +KHDRBS, Qua1 domain [IPR032571] 0.7647232909144748 3.044774515718151 0.0023285481608448 0.9983944471202072 0.0050209319718216 2 O75525 1 +Major facilitator superfamily domain [IPR020846] 0.8903873242925471 2.9923722357133564 0.0027681850927916 0.9995243294870684 0.0057445044030864 4 P53985,Q9H2V7 2 +Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252] 0.7546611423498109 2.9921083548600893 0.0027705790682743 0.9995274707294162 0.0057451526885329 2 Q86UL3 1 +Exosome complex component, N-terminal domain [IPR025721] 0.754365196803791 2.990554083716606 0.0027847181145901 0.9995456048339416 0.0057614857543244 2 Q13868 1 +tRNA/rRNA methyltransferase, SpoU type [IPR001537] 0.7460787215152445 2.9469114278787636 0.0032096512375598 0.999859862220148 0.0064345300250386 2 Q13395 1 +Peptidase M41 [IPR000642] 0.7416395383249516 2.923433195990935 0.0034619450319559 0.9999303164268548 0.0068055329688023 2 Q9Y4W6 1 +Armadillo repeat-containing domain [IPR006911] 0.8059213337985696 2.9141905853198766 0.0035661212271633 0.9999477821509856 0.0069619454319254 3 Q96D09 1 +ERAP1-like C-terminal domain [IPR024571] 0.8694107195735827 2.897247467907772 0.0037645267678543 0.9999698612847928 0.0072354414201099 4 P55786,Q6P179,Q9UIQ6 3 +DNA/RNA non-specific endonuclease [IPR001604] 0.7998815867377108 2.8845408168090345 0.0039198494098777 0.9999804012339129 0.0074592814667599 3 P22413,O94919 2 +Extracellular Endonuclease, subunit A [IPR020821] 0.7998815867377108 2.8845408168090345 0.0039198494098777 0.9999804012339129 0.0074592814667599 3 P22413,O94919 2 +Iron-binding zinc finger, CDGSH type [IPR018967] 0.7309854986682485 2.866803369803754 0.0041464054381159 0.9999895391484692 0.0078276874207934 2 Q9NZ45 1 +Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610] 0.7309854986682485 2.866803369803754 0.0041464054381159 0.9999895391484692 0.0078276874207934 2 Q9NZ45 1 +G-protein gamma-like domain [IPR015898] 0.7244746966558191 2.831998689716729 0.0046258038224202 0.9999972304875268 0.0085801199931989 2 P63218 1 +SUN coiled coil domain 2 [IPR040994] 0.7126368748150378 2.7683296060084825 0.005634444014416 0.9999998312827412 0.0100459079326797 2 O94901 1 +Syntaxin, N-terminal domain [IPR006011] 0.7693901716992214 2.733170426971842 0.0062727865345508 0.999999971330128 0.0109298553253538 3 Q13277,O15400 2 +Tim10-like [IPR004217] 0.8291382884216717 2.711427233937351 0.0066994243685443 0.9999999912361176 0.0115348791373564 4 Q9Y5J7,O60220,Q9Y5J9 3 +Fibronectin type II domain [IPR000562] 0.7637411548797794 2.7048138608204697 0.0068342673293761 0.9999999939748832 0.011708614419043 3 Q9UBV2 1 +PB1 domain [IPR000270] 0.7005031074282372 2.7025442350406443 0.0068811027630739 0.9999999947102104 0.0117669415279331 2 Q13501 1 +S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878] 0.6975436519680418 2.68641779577407 0.0072222717454841 0.9999999979507684 0.012304611121936 2 O43865 1 +NOPS [IPR012975] 0.7599171107163949 2.685562030966976 0.0072407932693858 0.9999999980536164 0.0123285560909963 3 Q15233,P23246 2 +Domain of unknown function DUF5600 [IPR040990] 0.6916247410476516 2.6540687744850087 0.0079527616086401 0.9999999997312844 0.0131671397959488 2 Q9H223 1 +EH domain-containing protein, N-terminal [IPR031692] 0.6916247410476516 2.6540687744850087 0.0079527616086401 0.9999999997312844 0.0131671397959488 2 Q9H223 1 +PABP, RNA recognition motif 2 [IPR045305] 0.6836342113051241 2.610193325028139 0.0090491067451028 0.9999999999872976 0.0146006222795595 2 P11940 1 +Complex 1 LYR protein domain [IPR008011] 0.7442273534635792 2.60609566154253 0.0091580880188069 0.9999999999906232 0.0147469795402024 3 Q9Y6M9,Q9NU23 2 +Copine, C-terminal [IPR010734] 0.7438317973008529 2.6040822526445155 0.0092120645811273 0.999999999991932 0.0147907494147245 3 Q86YQ8 1 +Copine, C2B domain [IPR037768] 0.7438317973008529 2.6040822526445155 0.0092120645811273 0.999999999991932 0.0147907494147245 3 Q86YQ8 1 +v-SNARE, coiled-coil homology domain [IPR042855] 0.7415051495341378 2.5922294802773456 0.0095356141823355 0.9999999999967246 0.0151690461920726 3 O15498 1 +Longin domain [IPR010908] 0.7415051495341378 2.5922294802773456 0.0095356141823355 0.9999999999967246 0.0151690461920726 3 O15498 1 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.7412572751722831 2.5909657147567917 0.0095707025975679 0.9999999999970296 0.0152073340064983 3 Q9UL46 1 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.7412572751722831 2.5909657147567917 0.0095707025975679 0.9999999999970296 0.0152073340064983 3 Q9UL46 1 +FAD dependent oxidoreductase [IPR006076] 0.8012627464775712 2.58028635628249 0.0098718418256296 0.9999999999987168 0.0155337989958596 4 Q9H9P8 1 +Intermediate filament head, DNA-binding domain [IPR006821] 0.8001113877104402 2.574824670971394 0.0100290910770823 0.9999999999991722 0.0157542921871072 4 P07196,P08670 2 +Glycosyl transferase, family 1 [IPR001296] 0.7341703148233145 2.554751423755589 0.0106263654858649 0.9999999999998436 0.0166168661422023 3 Q9BT22 1 +N-acetylgalactosaminyltransferase [IPR045885] 0.7261693309650715 2.5136753532074296 0.0119480363654349 0.999999999999996 0.0182392590534294 3 Q10471,Q10472 2 +RNA recognition motif domain [IPR000504] 0.3892435785590482 2.4974366780400623 0.0125094804533363 0.9999999999999992 0.018928819107022 120 P09012,Q9BWF3,P98179,Q15287,P26368,P55795,Q86V81,Q16629,P35637,P84103,P62995,P11940,O43251,P22626,Q8WXF1,Q13151,O43390,Q99729,Q86U42,Q15233,O60506,P31943,P38159,P07910,Q9Y6M1,P52272,Q92804,Q9UKM9,Q01085,P98175,P51991,Q13595,Q14011,P52597,P31483,P09651,Q96PK6,Q96E39,Q9UN86,Q14103,P31942,Q9UHX1,Q01844,P23246,O14979,P52756,Q07955 47 +Lamin tail domain [IPR001322] 0.7229709101140189 2.4971981474601592 0.0125178987629488 0.9999999999999992 0.0189311784031445 3 Q03252 1 +RH2 domain [IPR034744] 0.6549274933412299 2.4506110275458934 0.0142613972686596 1.0 0.0209704083439001 2 O60271 1 +RH1 domain [IPR034743] 0.6549274933412299 2.4506110275458934 0.0142613972686596 1.0 0.0209704083439001 2 O60271 1 +JNK/Rab-associated protein-1, N-terminal [IPR019143] 0.6549274933412299 2.4506110275458934 0.0142613972686596 1.0 0.0209704083439001 2 O60271 1 +Leucine-rich repeat N-terminal domain [IPR000372] 0.6490085824208396 2.417323851867716 0.0156350994586791 1.0 0.0227064016597605 2 Q13641 1 +Cysteine-rich flanking region, C-terminal [IPR000483] 0.6490085824208396 2.417323851867716 0.0156350994586791 1.0 0.0227064016597605 2 Q13641 1 +MIRO domain [IPR020860] 0.6448653447765662 2.3939443538449536 0.0166682774024784 1.0 0.0238612269869504 2 Q8IXI1 1 +EF hand associated, type-1 [IPR013566] 0.6448653447765662 2.3939443538449536 0.0166682774024784 1.0 0.0238612269869504 2 Q8IXI1 1 +EF hand associated, type-2 [IPR013567] 0.6448653447765662 2.3939443538449536 0.0166682774024784 1.0 0.0238612269869504 2 Q8IXI1 1 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.7432053991727349 2.300355265520252 0.0214281010250259 1.0 0.0294970368224795 4 P98194,P05023 2 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.7432053991727349 2.300355265520252 0.0214281010250259 1.0 0.0294970368224795 4 P98194,P05023 2 +Zinc finger, RanBP2-type [IPR001876] 0.7663127014310357 2.294609664777456 0.0217555039000301 1.0 0.0298848063745818 9 P52756,P35637,Q92804,P98175 4 +ZU5 domain [IPR000906] 0.6137910624445158 2.216533193274344 0.0266550071948874 1.0 0.0357125339115967 2 Q07157 1 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.7719188738787653 2.2093034788719335 0.0271535393873814 1.0 0.0362572659454149 5 P13674,Q32P28,O15460 3 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.6120153891683986 2.2062853785829413 0.0273640244874553 1.0 0.0364853659832737 2 P51116 1 +Pleckstrin homology domain, spectrin-type [IPR001605] 0.6114234980763597 2.2028668032758145 0.027604138010234 1.0 0.0366638214187902 2 O15020 1 +Pleckstrin homology domain 9 [IPR041681] 0.6114234980763597 2.2028668032758145 0.027604138010234 1.0 0.0366638214187902 2 O15020 1 +GOLD domain [IPR009038] 0.8068148148147992 2.1506581055845944 0.0315031953899556 1.0 0.0409363555914677 6 P49755,Q9Y3A6,Q9BVK6,Q15363,Q13445 5 +Target SNARE coiled-coil homology domain [IPR000727] 0.7102622255374266 2.138132103184896 0.0325060230459637 1.0 0.0419040745478093 10 O95721,O15400,Q13190,O60499,O43752 5 +L27 domain, C-terminal [IPR014775] 0.7397433713749744 2.057322430533189 0.0396552211238911 1.0 0.0497719010013368 5 Q9NZW5,Q8N3R9 2 +Survival motor neuron [IPR010304] 0.5844924533885827 2.0459348940320847 0.040762776664148 1.0 0.0509022680895796 2 O75940 1 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.7748375973755848 2.006584755689639 0.0447938958400222 1.0 0.0551432437638097 6 Q9HD20,P98194,P05023 3 +Phospholipid/glycerol acyltransferase [IPR002123] 0.7230450236966749 1.977458461092137 0.0479898314262929 1.0 0.0587109639789754 5 Q8NF37,Q9HCL2,Q92604,Q86UL3 4 +Glycosyltransferase 2-like [IPR001173] 0.716569193756951 1.9463075021183347 0.0516178129649156 1.0 0.0625121385621619 5 O60762,Q10471,Q10472 3 +Intermediate filament, rod domain [IPR039008] 0.7135668716136672 1.9189046535137235 0.0549964016038293 1.0 0.06582396722748 8 P07196,P07197,Q03252,P08670,P20700 5 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.6664475199010605 1.916040786767972 0.0553599043113868 1.0 0.0661156797487787 4 O60749 1 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.7337059404899926 1.9129118146008577 0.0557593428190625 1.0 0.0663916247543627 7 O15173,Q9UMX5,O00264,O43169 4 +Agenet-like domain [IPR008395] 0.612196566015396 1.90636067410109 0.0566034272472257 1.0 0.0671937458934809 3 P51116,Q06787 2 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.612196566015396 1.90636067410109 0.0566034272472257 1.0 0.0671937458934809 3 P51116,Q06787 2 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.612196566015396 1.90636067410109 0.0566034272472257 1.0 0.0671937458934809 3 P51116,Q06787 2 +Fxr1, tudor domain [IPR041560] 0.612196566015396 1.90636067410109 0.0566034272472257 1.0 0.0671937458934809 3 P51116,Q06787 2 +Class II aldolase/adducin N-terminal [IPR001303] 0.6059798697454104 1.8720631477449212 0.061197867666672 1.0 0.0716918993039111 3 Q9UEY8,P35611 2 +Ribosomal protein/NADH dehydrogenase domain [IPR007741] 0.5537141166025517 1.8633315364704444 0.0624156358084497 1.0 0.0729018852438939 2 Q8N983 1 +ALIX V-shaped domain [IPR025304] 0.5525303344184739 1.8562413636432544 0.0634191627074669 1.0 0.0740113695867267 2 Q9H3S7 1 +Sec23, C-terminal [IPR037550] 0.5489789878662394 1.834941972438521 0.0665142877824205 1.0 0.0769402490693548 2 Q15437 1 +LEM domain [IPR003887] 0.7340623298374231 1.8197067818968689 0.0688036699805563 1.0 0.079494476946408 6 P50402,Q86XL3 2 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.7328523705908714 1.8141091113681984 0.0696609290933736 1.0 0.0803108455713079 6 O60313,Q8IWA4 2 +Dynamin, N-terminal [IPR045063] 0.7328523705908714 1.8141091113681984 0.0696609290933736 1.0 0.0803108455713079 6 O60313,Q8IWA4 2 +Complement Clr-like EGF domain [IPR026823] 0.5327019828351653 1.7367788519166791 0.0824262132900091 1.0 0.0943968251785996 2 P98164 1 +Ribosomal protein L26/L24, KOW domain [IPR041988] 0.531222255105066 1.727812117522502 0.084021914194591 1.0 0.0961843563571428 2 P61254 1 +Chromo domain subgroup [IPR017984] 0.5797148985920038 1.7259212568974331 0.0843615799380337 1.0 0.0964931457227406 3 Q13185 1 +Chromo shadow domain [IPR008251] 0.5797148985920038 1.7259212568974331 0.0843615799380337 1.0 0.0964931457227406 3 Q13185 1 +MoaB/Mog domain [IPR001453] 0.5294465818289504 1.7170428920415828 0.0859713353220361 1.0 0.0982936559605715 2 Q8NFF5 1 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.5921042699188893 1.67900339764601 0.0931513815886835 1.0 0.1062826842433925 12 Q9NWM8,O95302 2 +Acyl-CoA-binding protein, ACBP [IPR000582] 0.5693306546100935 1.66761679612558 0.0953918218459337 1.0 0.1085696611524854 3 Q5T8D3 1 +Gamma tubulin complex component protein, N-terminal [IPR041470] 0.5193844332642867 1.6558332801269482 0.0977555861484735 1.0 0.1111224949628447 2 Q9BSJ2 1 +Gamma tubulin complex component, C-terminal [IPR040457] 0.5193844332642867 1.6558332801269482 0.0977555861484735 1.0 0.1111224949628447 2 Q9BSJ2 1 +Man1/Src1, C-terminal [IPR018996] 0.5161290322580719 1.6359651667073782 0.1018468778277419 1.0 0.1156779353105217 2 Q9Y2U8 1 +Cobalamin (vitamin B12)-binding domain [IPR006158] 0.512873631251857 1.61606641863766 0.1060799537968657 1.0 0.1201397917436805 2 Q99707 1 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.6484624496376371 1.593375001809426 0.1110760902274721 1.0 0.1253865067598458 8 P13674,Q32P28,O15460 3 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.6484624496376371 1.593375001809426 0.1110760902274721 1.0 0.1253865067598458 8 P13674,Q32P28,O15460 3 +Band 7 domain [IPR001107] 0.6394900681885712 1.5478098975942485 0.1216680728204988 1.0 0.136672316233039 8 P35232,Q99623,Q9UJZ1,O75477,P27105,O75955,Q14254 7 +SPRY-associated [IPR006574] 0.5470692717584488 1.5417177334523475 0.1231422007000238 1.0 0.1382719584752098 3 P19474,Q12899 2 +Cadherin-like [IPR002126] 0.6722643194306391 1.5303029901533434 0.1259417484968206 1.0 0.141300498313506 6 Q14574,Q9BQT9 2 +RNA recognition motif domain, eukaryote [IPR003954] 0.5439528328747905 1.5185702575505584 0.1288707023856432 1.0 0.144527890525955 14 Q14011,P31483,Q96E39,Q9UHX1,Q01085,P38159 6 +K Homology domain, type 1 [IPR004088] 0.4532327512319146 1.5008510050544168 0.1333941029441849 1.0 0.1492370182918324 26 Q9Y6M1,P61978,Q96I24,Q9UNW9,Q96AE4,Q9Y2W6,Q92945,O75525 8 +Ribosomal L28e/Mak16 [IPR029004] 0.4909736608464121 1.481466140887323 0.1384824010959069 1.0 0.1546162730682456 2 Q9BXY0 1 +K Homology domain [IPR004087] 0.448745870999032 1.4641546252181492 0.1431517047959096 1.0 0.1595713672199962 26 P61978,Q9Y2W6,Q96I24,Q96AE4,Q9UNW9,Q92945,O75525 7 +EF-hand domain [IPR002048] 0.3900568231141103 1.4570445161149028 0.1451040924673845 1.0 0.1614217231801617 50 Q9NWM8,Q14257,O43852,O95202,Q8IYU8,Q9BPX6,O95302,Q9Y680,P80303,Q96D71,P41208,P0DP25 12 +Isopropylmalate dehydrogenase-like domain [IPR024084] 0.6165657392515493 1.4537394324587989 0.1460185612404818 1.0 0.1623735813955398 5 P48735 1 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.6549359092342563 1.4480172376224665 0.1476122297986726 1.0 0.1640135886651917 6 Q6P179,Q9UIQ6,P55786 3 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.6549359092342563 1.4480172376224665 0.1476122297986726 1.0 0.1640135886651917 6 Q6P179,Q9UIQ6,P55786 3 +Dynamin GTPase effector [IPR003130] 0.4844628588339824 1.441228827558501 0.1495200467613431 1.0 0.1657996500848963 2 P50570 1 +Dynamin stalk domain [IPR000375] 0.4844628588339824 1.441228827558501 0.1495200467613431 1.0 0.1657996500848963 2 P50570 1 +GTPase effector domain [IPR020850] 0.4844628588339824 1.441228827558501 0.1495200467613431 1.0 0.1657996500848963 2 P50570 1 +HD/PDEase domain [IPR003607] 0.4835750221959239 1.4357350496758188 0.1510777477451093 1.0 0.1673252743886443 2 Q9Y3Z3 1 +HD domain [IPR006674] 0.4835750221959239 1.4357350496758188 0.1510777477451093 1.0 0.1673252743886443 2 Q9Y3Z3 1 +Immunoglobulin-like domain [IPR007110] 0.5254876598115047 1.4028776658405122 0.1606533219402117 1.0 0.1771822027314645 14 P35613,P10321,P01889,Q08722,P10586 5 +EH domain [IPR000261] 0.6056421758811881 1.3988396074302227 0.1618610860731362 1.0 0.1784091843298146 5 Q96D71 1 +Ricin B, lectin domain [IPR000772] 0.5804463098664464 1.2716902110575286 0.2034832100053356 1.0 0.2225975662365146 5 Q10471,Q10472,Q9UBG0 3 +Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468] 0.4563480319621275 1.2666263885965403 0.2052889121755021 1.0 0.2241287174067982 2 A0FGR8 1 +Extended synaptotagmin, C-terminal C2 domain [IPR037752] 0.4563480319621275 1.2666263885965403 0.2052889121755021 1.0 0.2241287174067982 2 A0FGR8 1 +Extended synaptotagmin, C2B domain [IPR037749] 0.4563480319621275 1.2666263885965403 0.2052889121755021 1.0 0.2241287174067982 2 A0FGR8 1 +Synaptotagmin, SMP domain [IPR039010] 0.4563480319621275 1.2666263885965403 0.2052889121755021 1.0 0.2241287174067982 2 A0FGR8 1 +Extended synaptotagmin, C2A domain [IPR037733] 0.4563480319621275 1.2666263885965403 0.2052889121755021 1.0 0.2241287174067982 2 A0FGR8 1 +Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.4956705121667296 1.247404944828639 0.2122490543578865 1.0 0.2313615284469853 3 Q1KMD3 1 +EF-hand, Ca insensitive [IPR014837] 0.5368670417530291 1.2354984891096823 0.2166450384232103 1.0 0.2357808777792037 4 P12814,Q13813,P35609 3 +Exportin-2, central domain [IPR013713] 0.4928952042628827 1.231423996035744 0.2181643267657111 1.0 0.2372472584213407 3 P55060,O15397 2 +Phox homology [IPR001683] 0.5139833969739249 1.2153224774442273 0.2242431222424588 1.0 0.2435698612314782 12 Q9UNH7,Q9Y5X3,O60749,Q9Y2I1,Q96L92 5 +Adenylate kinase, active site lid domain [IPR007862] 0.4757252812315008 1.132511480897292 0.2574194603582267 1.0 0.2782913084953802 3 P54819,P27144 2 +BRO1 domain [IPR004328] 0.4748371817643563 1.1273960290393763 0.2595750772434553 1.0 0.2805118297540864 3 Q8WUM4,Q9H3S7 2 +CBS domain [IPR000644] 0.5878868573644737 1.1267978601098294 0.2598279554801754 1.0 0.280675208268213 6 P51798,Q6P4Q7,Q8NE01,P51790 4 +Guanylate kinase-like domain [IPR008144] 0.5318389393384428 1.0747801847053888 0.2824731540270391 1.0 0.3038292693353966 9 Q9NZW5,Q8N3R9 2 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.5318389393384428 1.0747801847053888 0.2824731540270391 1.0 0.3038292693353966 9 Q9NZW5,Q8N3R9 2 +G-patch domain [IPR000467] 0.4730656086770872 1.070999408587347 0.2841696955663804 1.0 0.305535005751153 14 P98175 1 +GCF, C-terminal [IPR022783] 0.460035523978697 1.042219464173372 0.2973099409046993 1.0 0.3187938760283489 3 Q9UBB9,Q9Y5B6 2 +Zinc finger, TFIIB-type [IPR013137] 0.4190588931636642 1.034351057981658 0.3009720756164249 1.0 0.3224700810175981 2 P29083 1 +Major sperm protein (MSP) domain [IPR000535] 0.449970396684436 0.9844549918404628 0.3248918508418728 1.0 0.3470207075555607 3 Q8NHP6,Q9P0L0 2 +MCM, AAA-lid domain [IPR041562] 0.5511173795097929 0.950494527332202 0.3418610333485175 1.0 0.3638783077678011 6 Q14566,P33991 2 +MCM OB domain [IPR033762] 0.5511173795097929 0.950494527332202 0.3418610333485175 1.0 0.3638783077678011 6 Q14566,P33991 2 +MCM domain [IPR001208] 0.5511173795097929 0.950494527332202 0.3418610333485175 1.0 0.3638783077678011 6 Q14566,P33991 2 +MCM N-terminal domain [IPR027925] 0.5511173795097929 0.950494527332202 0.3418610333485175 1.0 0.3638783077678011 6 Q14566,P33991 2 +Tyrosine-protein kinase, catalytic domain [IPR020635] 0.5125625248564332 0.9285009741391738 0.3531477627240336 1.0 0.3757470412946541 5 P00533,Q15375 2 +CTP synthase, N-terminal [IPR017456] 0.4004143237644341 0.9189094158107276 0.3581429545350945 1.0 0.3806216998524685 2 Q9NRF8 1 +CTP synthase GATase domain [IPR033828] 0.4004143237644341 0.9189094158107276 0.3581429545350945 1.0 0.3806216998524685 2 Q9NRF8 1 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.4381957788590276 0.9171517297058368 0.3590631370818675 1.0 0.3814527553294666 3 O60884 1 +Peptidase M16, N-terminal [IPR011765] 0.5208137989518438 0.8674936169096782 0.3856716076624442 1.0 0.4087763583518994 7 P22695 1 +Peptidase M16, C-terminal [IPR007863] 0.5208137989518438 0.8674936169096782 0.3856716076624442 1.0 0.4087763583518994 7 P22695 1 +Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585] 0.3909440662918101 0.8607193500466025 0.3893926331701252 1.0 0.4125618685410923 2 Q08170 1 +YTH domain [IPR007275] 0.4644323662822995 0.849440460543837 0.3956362472427126 1.0 0.4187794792603966 4 Q9H6S0 1 +Tudor domain [IPR002999] 0.4995045335926743 0.8277468926461052 0.4078138564825961 1.0 0.431251434441366 8 Q9Y2W6 1 +EGF-like calcium-binding domain [IPR001881] 0.4412200177672381 0.7283939102174816 0.4663724900379082 1.0 0.4914807455153214 4 O94813,Q07954,P98164 3 +SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.3897524406361425 0.6464938837746047 0.5179595568496664 1.0 0.5431490793712308 3 Q08J23 1 +Heat shock protein Hsp90, N-terminal [IPR020575] 0.4216760438258672 0.628744940200858 0.5295160516318691 1.0 0.5535849630696813 4 P07900,Q12931,P14625 3 +Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791] 0.351583308671212 0.62487861461398 0.532050729011007 1.0 0.5555844958763163 2 Q9NVE7 1 +Zinc finger, CCHC-type [IPR001878] 0.4524391634987446 0.592793557036529 0.553319320142466 1.0 0.5760699070513792 8 Q9NUD5,Q9BWF3 2 +Ubiquitin conjugation factor E4, core [IPR019474] 0.3427049422906263 0.5736804620750109 0.5661840519574255 1.0 0.5881324739941642 2 O95155 1 +Ribosomal protein S10 domain [IPR027486] 0.3335306303640212 0.5218490304424658 0.6017754486613156 1.0 0.6234610504148765 2 Q96GC5 1 +Mu homology domain [IPR028565] 0.3991708617115717 0.5176834424786756 0.6046791524273711 1.0 0.6262343192118366 4 Q9Y2T2,P48444,Q9BXS5 3 +Kinesin-like [IPR022164] 0.3605683836589701 0.4923732887593158 0.6224554786834315 1.0 0.644160900324811 3 O60333,Q9Y3P9 2 +Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798] 0.3255401006214936 0.4777243120508526 0.6328464379215304 1.0 0.6544234427363896 2 Q9UKA9 1 +Disulphide isomerase [IPR005788] 0.4117298578199 0.4445670211804441 0.6566326846707065 1.0 0.6782583120101608 5 Q8NBS9,Q15084,P13667,P07237 4 +Ubiquitin-like domain, USP-type [IPR028135] 0.3131103876886736 0.4112635459794106 0.6808792968496677 1.0 0.7017277293895007 2 Q9Y4E8 1 +Zinc finger, CW-type [IPR011124] 0.3068955312222636 0.3791536653070074 0.7045737569199475 1.0 0.723715507666191 2 Q8NB78 1 +ELMO domain [IPR006816] 0.2994968925717752 0.3420127644115601 0.7323412862825727 1.0 0.750840248937556 2 Q8IZ81 1 +SCP2 sterol-binding domain [IPR003033] 0.3294849023090564 0.3409870631055401 0.733113320885675 1.0 0.7513526794075244 3 P22307,P51659 2 +PTBP1, RNA recognition motif 2-like [IPR021790] 0.32563647128478 0.3234329558770134 0.7463673744153048 1.0 0.7643688138724457 3 P14866,Q9UKA9 2 +Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.3822077355076195 0.3140181992903598 0.7535072163663357 1.0 0.7702518211744764 9 O15254 1 +4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.3182356423919413 0.2905300439097321 0.7714107697476891 1.0 0.7876780334826571 3 P21912,Q16134 2 +Sec63 domain [IPR004179] 0.3164594434576614 0.2828079465982913 0.7773240624086541 1.0 0.793422489736644 3 Q8N3C0,Q9UGP8 2 +AP complex, mu/sigma subunit [IPR022775] 0.3994074074074105 0.280881675235135 0.7788011561285986 1.0 0.7946362997837086 6 P61923,P48444,P53680,Q9Y2T2,Q92572 5 +Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346] 0.3132030787448152 0.2688331756776374 0.7880580623149833 1.0 0.8023018266283121 3 Q93009,Q9Y4E8 2 +Zinc finger, FYVE-related [IPR017455] 0.3658175355450178 0.2554069818584166 0.7984087788335268 1.0 0.8122404089865588 5 Q96T51,Q15075,Q9P2R3,O14964 4 +FYVE zinc finger [IPR000306] 0.3658175355450178 0.2554069818584166 0.7984087788335268 1.0 0.8122404089865588 5 Q96T51,Q15075,Q9P2R3,O14964 4 +PDZ domain [IPR001478] 0.2951029588646456 0.2270356230805525 0.8203960421283751 1.0 0.8324606898067336 28 Q8N3R9,P57105,Q9NZW5,Q96L92,O43464 5 +Immunoglobulin subtype [IPR003599] 0.3341364760225641 0.1508249394079215 0.8801138125082721 1.0 0.8891340126364682 10 P35613,P10586 2 +Immunoglobulin subtype 2 [IPR003598] 0.3396992012125734 0.1425996856824079 0.8866063457335072 1.0 0.8943835943802922 9 P35613,P10586 2 +L27 domain [IPR004172] 0.345465400172536 0.1383653299568307 0.8899516961056846 1.0 0.8974302817872449 8 Q9NZW5,Q8N3R9 2 +Protein kinase, C-terminal [IPR017892] 0.3505639390289486 0.1347075644088488 0.8928430921752482 1.0 0.9000171418567147 7 P31751 1 +BTB/POZ domain [IPR000210] 0.3434074074074103 0.0982918332120302 0.9217005629331184 1.0 0.9274128886968308 6 Q08380,Q96RE7,Q9P2R3,Q9NXV2,Q96CX2 5 +GAT domain [IPR004152] 0.2593250444049662 0.0773428502645813 0.9383508033945492 1.0 0.943134820600494 3 O60784,Q9UJY4 2 +14-3-3 domain [IPR023410] 0.3333333333333356 0.0716513779866233 0.942879351393718 1.0 0.9473414669991488 6 P62258,Q04917,P31946,P61981,P63104 5 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6ab4093efb862b53b806e3d505117e60fb871529 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-3' exoribonuclease 1, SH3-like domain [IPR041385]", "5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal [IPR039137]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA lid domain [IPR041083]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC-type uncharacterised transport system [IPR019196]", "ABC1 atypical kinase-like domain [IPR004147]", "ABT1/ESF2, RNA recognition motif [IPR034353]", "ADAM, cysteine-rich domain [IPR006586]", "ADAM10/ADAM17 catalytic domain [IPR034025]", "ADAM17, membrane-proximal domain [IPR032029]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adenomatous polyposis coli protein basic domain [IPR009234]", "Adenomatous polyposis coli, N-terminal dimerisation domain [IPR032038]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin [IPR001599]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-2-macroglobulin, TED domain [IPR041813]", "Alpha-2-macroglobulin, bait region domain [IPR011625]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha-macroglobulin, receptor-binding [IPR009048]", "Alpha-macroglobulin-like, TED domain [IPR011626]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B(0)AT2, solute-binding domain [IPR042934]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Basic-leucine zipper domain [IPR004827]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-lactamase-related [IPR001466]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brd8, Bromo domain [IPR037966]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C19orf47, SAM domain [IPR040772]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCDC93, coiled-coil domain [IPR019159]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COQ9 [IPR013718]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPPED1, metallophosphatase domain [IPR041867]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CUT domain [IPR003350]", "CXC domain [IPR026489]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, N-terminal [IPR013164]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium binding and coiled-coil domain-like [IPR012852]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Calsyntenin, C-terminal [IPR045588]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cdc6, C-terminal [IPR015163]", "Cell division control protein 73, C-terminal [IPR031336]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centrosomin, N-terminal motif 1 [IPR012943]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Clusterin, C-terminal [IPR016015]", "Clusterin, N-terminal [IPR016014]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coactivator CBP, pKID [IPR003102]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complement Clr-like EGF domain [IPR026823]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-A, N-terminal APC/C binding region [IPR032447]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "Cytosolic fatty-acid binding [IPR000463]", "D domain of beta-TrCP [IPR021977]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEP domain [IPR000591]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIX domain [IPR001158]", "DJ-1/PfpI [IPR002818]", "DM10 domain [IPR006602]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase 3-like, TOPRIM domain [IPR034144]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IA, DNA-binding domain [IPR003602]", "DNA topoisomerase, type IA, central [IPR013497]", "DNA topoisomerase, type IA, domain 2 [IPR003601]", "DNA topoisomerase, type IA, zn finger [IPR013498]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-binding protein SMUBP-2, R3H domain [IPR034072]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DUS-like, FMN-binding domain [IPR035587]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dis3-like cold-shock domain 2 [IPR041505]", "Dishevelled C-terminal [IPR024580]", "Dishevelled protein domain [IPR003351]", "Disintegrin domain [IPR001762]", "Disks large homologue 1, N-terminal PEST domain [IPR019590]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4171 [IPR025228]", "Domain of unknown function DUF4195 [IPR025243]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5050 [IPR032485]", "Domain of unknown function DUF5577 [IPR041477]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Drought induced 19 protein type, zinc-binding domain [IPR008598]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase RNF114, RING finger, HC subclass [IPR042716]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB-1 binding [IPR009232]", "EB1, C-terminal [IPR004953]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELK domain [IPR005539]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXOG, C-terminal [IPR041003]", "EXPERA domain [IPR033118]", "EYA domain [IPR006545]", "EYA domain, metazoan [IPR042577]", "EZH2, SET domain [IPR044439]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease Xrn1, D2/D3 domain [IPR041106]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM3C (ILEI) domain [IPR039475]", "FAM69, protein-kinase domain [IPR022049]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FNBP1L, F-BAR domain [IPR035494]", "FNBP1L, SH3 domain [IPR035493]", "FOX1, RNA recognition motif [IPR034237]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Follistatin/Osteonectin EGF domain [IPR015369]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fox-1 C-terminal domain [IPR025670]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Furin-like cysteine-rich domain [IPR006211]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-butyrobetaine hydroxylase-like, N-terminal [IPR010376]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycosyltransferase subfamily 4-like, N-terminal domain [IPR028098]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Growth factor receptor domain 4 [IPR032778]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Hermansky-Pudlak syndrome 3 protein, C-terminal domain [IPR029438]", "Hermansky-Pudlak syndrome 3 protein, N-terminal domain [IPR029437]", "Hermansky-Pudlak syndrome 3, central region [IPR028167]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone chaperone domain CHZ [IPR019098]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox protein Hox1A3 N-terminal [IPR022067]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "Hpc2-related domain [IPR014840]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Int12, PHD finger [IPR039054]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kazal domain [IPR002350]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-1 [IPR015143]", "L27-2 [IPR015132]", "L27-N [IPR015145]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM2, LYR domain [IPR045293]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipocalin/cytosolic fatty-acid binding domain [IPR000566]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MABP domain [IPR023341]", "MAGE homology domain [IPR002190]", "MAM domain [IPR000998]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MMS22-like, C-terminal [IPR029424]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP5, SH3 domain [IPR035601]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MTMR6, PH-GRAM domain [IPR035998]", "MYND-like zinc finger [IPR031615]", "MYST, zinc finger domain [IPR040706]", "Mab-21 domain [IPR024810]", "Macro domain [IPR002589]", "Macroglobulin domain MG3 [IPR041555]", "Macroglobulin domain [IPR002890]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med12 [IPR019035]", "Mediator complex, subunit Med12, LCEWAV-domain [IPR021990]", "Mediator complex, subunit Med12, catenin-binding [IPR021989]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NACHT nucleoside triphosphatase [IPR007111]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDPK7, first NDPk domain [IPR035525]", "NDPK7, second NDPk domain [IPR037993]", "NDUFA6, LYR domain [IPR045299]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFRKB winged helix-like domain [IPR025220]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Nck1, SH2 domain [IPR035882]", "Nck1, SH3 domain 1 [IPR035562]", "Nck1, SH3 domain 2 [IPR035564]", "Nck1, SH3 domain 3 [IPR035565]", "Nck2, SH2 domain [IPR035883]", "Nck2, SH3 domain 1 [IPR035559]", "Nck2, SH3 domain 2 [IPR035560]", "Nck2, SH3 domain 3 [IPR035561]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurabin-1/2, PDZ domain [IPR040645]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Neuropilin, C-terminal [IPR022579]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal [IPR018849]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Olduvai domain [IPR010630]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, C-terminal [IPR032630]", "P-type ATPase, N-terminal [IPR032631]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PDZ-associated domain of NMDA receptors [IPR019583]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRELI/MSF1 domain [IPR006797]", "PRKAA1, UBA-like autoinhibitory domain [IPR028797]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Patatin-like phospholipase domain [IPR002641]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C1A, propeptide [IPR012599]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M12B, ADAM/reprolysin [IPR001590]", "Peptidase M12B, propeptide [IPR002870]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D-like domain [IPR025202]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine interaction domain, Shc-like [IPR006019]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polycomb repressive complex 2 subunit EZH1/EZH2, tri-helical domain [IPR041343]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET CXC domain [IPR041355]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein FAM210A/B-like domain [IPR009688]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein MMS22-like, N-terminal [IPR029425]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein OS9-like domain [IPR012913]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein disulfide-isomerase A5, N-terminal TRX-like b domain [IPR041865]", "Protein kinase B alpha, catalytic domain [IPR034676]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Proto-oncogene c-Rel, RHD, N-terminal subdomain [IPR042845]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine 5'-phosphate oxidase, putative [IPR011576]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal [IPR019576]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM15B, RNA recognition motif 1 [IPR034475]", "RBM15B, RNA recognition motif 2 [IPR034535]", "RBM15B, RNA recognition motif 3 [IPR034536]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RII binding domain [IPR018459]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 2-O ribose methyltransferase, substrate binding [IPR013123]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab interacting lysosomal protein, dimerization domain [IPR021563]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rabaptin coiled-coil domain [IPR018514]", "Rabaptin, GTPase-Rab5 binding domain [IPR015390]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Rapamycin-insensitive companion of mTOR, N-terminal domain [IPR028267]", "Rapamycin-insensitive companion of mTOR, domain 4 [IPR029453]", "Rapamycin-insensitive companion of mTOR, domain 5 [IPR029452]", "Rapamycin-insensitive companion of mTOR, middle domain [IPR029451]", "Raptor, N-terminal CASPase-like domain [IPR029347]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "RecQ helicase-like 5 [IPR010716]", "Receptor L-domain [IPR000494]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reprolysin domain, adamalysin-type [IPR034027]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Rhs repeat-associated core [IPR022385]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SAS-6 coiled-coil domain [IPR041513]", "SATB, CUT1-like DNA-binding domain [IPR032355]", "SATB, ubiquitin-like oligomerisation domain [IPR032392]", "SCAF4, RNA recognition motif [IPR034369]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD7, SET domain [IPR044436]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 adaptor protein C, SH2 domain [IPR035676]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SH3PXD2, PX domain [IPR037961]", "SH3PXD2B, SH3 domain 1 [IPR035477]", "SH3PXD2B, SH3 domain 2 [IPR035478]", "SH3PXD2B, SH3 domain 3 [IPR035479]", "SH3PXD2B, SH3 domain 4 [IPR035480]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Sequestosome-1, PB1 domain [IPR034866]", "Sequestosome-1, UBA domain [IPR033741]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Siah interacting protein, N-terminal [IPR015120]", "Sialidase [IPR011040]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm8 [IPR034103]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Somatomedin B domain [IPR001212]", "Somatomedin B, chordata [IPR020436]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spindle assembly abnormal protein 6, N-terminal [IPR032396]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Strawberry notch, AAA domain [IPR039187]", "Strawberry notch, helicase C domain [IPR026937]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfatase-modifying factor enzyme [IPR005532]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAFH/NHR1 [IPR003894]", "TAFII55 protein, conserved region [IPR006751]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TGS [IPR004095]", "THADA/TRM732, DUF2428 [IPR019442]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUG ubiquitin-like domain [IPR021569]", "TUP1-like enhancer of split [IPR011494]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "TauD/TfdA-like domain [IPR003819]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Teneurin intracellular, N-terminal [IPR009471]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Tesmin/TSO1-like CXC domain [IPR033467]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat protein 5, OB fold domain [IPR032076]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tex protein, YqgF-like domain [IPR032639]", "Tex, S1 domain [IPR044146]", "Tex-like protein, N-terminal [IPR018974]", "Tfc3, extended winged-helix domain [IPR035625]", "Thg1 C-terminal domain [IPR025845]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Tox-GHH domain [IPR028916]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription initiation factor TFIID component TAF4, C-terminal [IPR007900]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tuberin, N-terminal [IPR024584]", "Tuberin-type domain [IPR018515]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Lyn, SH2 domain [IPR035852]", "Tyrosine-protein kinase Lyn, SH3 domain [IPR035748]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glucuronate decarboxylase N-terminal [IPR021761]", "UDP-glycosyltransferase family, conserved site [IPR035595]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubinuclein middle domain [IPR026947]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific peptidase 1 [IPR033815]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Unconventional myosin-Ie/If, SH3 domain [IPR035507]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat protein mio, zinc-ribbon like domain [IPR031488]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WIBG, Mago-binding [IPR015362]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, D1 domain [IPR040992]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZCRB1, RNA recognition motif [IPR034219]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "ZZEF1, zinc finger, ZZ-type [IPR041986]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger C2HC RNF-type [IPR034734]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, AN1-type [IPR000058]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "mRNA decapping enzyme 2 , NUDIX hydrolase domain [IPR044099]", "mRNA decapping protein 2, Box A domain [IPR007722]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNAHis guanylyltransferase catalytic domain [IPR024956]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "APLP2", "APMAP", "APOBEC3C", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP17", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMC10", "ARMCX3", "ARMT1", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAP18", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCOR", "BCS1L", "BIRC6", "BLM", "BLVRA", "BMS1", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRIX1", "BROX", "BSG", "BTF3", "BTRC", "BUB1B", "BUD23", "BZW1", "BZW2", "C19orf47", "C1orf35", "C2CD2L", "C2CD5", "C3orf58", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC93", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CD109", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC34", "CDC37", "CDC42", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP170", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHP1", "CHRAC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLSTN3", "CLTC", "CLU", "CLUH", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNPY2", "COA3", "COIL", "COLEC12", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREB1", "CRKL", "CRYZ", "CRYZL1", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNBL1", "CTPS1", "CTPS2", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC22", "CWF19L1", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCP1A", "DCP2", "DCTN1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM129B", "FAM208A", "FAM210B", "FAM3C", "FAM49B", "FAM8A1", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1L", "FNBP4", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA4", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRASP2", "GPS1", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HPS3", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS11", "INTS12", "INTS14", "INTS3", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPRIP", "IVD", "IWS1", "JMJD6", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KIN", "KMT2A", "KNOP1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8C", "LRSAM1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBD3", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED25", "MEPCE", "METAP1", "METTL13", "MFAP1", "MFF", "MFN1", "MFSD10", "MGME1", "MIA2", "MIA3", "MICU1", "MICU2", "MINDY3", "MIOS", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MMS22L", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDZ", "MPHOSPH8", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL11", "MRPL12", "MRPL15", "MRPL2", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA40", "NAA50", "NACC1", "NAE1", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCK1", "NCK2", "NCKIPSD", "NCL", "NCLN", "NCSTN", "NDUFA10", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NTHL1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCID2", "PCK2", "PCM1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDXK", "PDZD11", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "POP1", "POR", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP1R9B", "PPP3CA", "PPP4C", "PPP4R3A", "PPP5C", "PPP6C", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRELID1", "PREP", "PREPL", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "PYCR3", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDX", "RECQL", "RECQL4", "RECQL5", "REL", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIF1", "RILPL1", "RIOX1", "RIOX2", "RNASEH2A", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRP12", "RSF1", "RTCA", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF11", "SCAF4", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A2", "SLC27A4", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAU1", "STAU2", "STIP1", "STK4", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TKT", "TLN1", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMF1", "TMLHE", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSR1", "TST", "TSTA3", "TTC4", "TTC5", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UBA1", "UBA2", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBLCP1", "UBN2", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "URB2", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VCP", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS29", "VPS37B", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WASF2", "WASHC4", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "WNK3", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YBX1", "YES1", "YKT6", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZYX", "ZZEF1"], "leading_proteins": ["ACBD5", "ACOX3", "ACTN1", "ACTN2", "ADD1", "ADD3", "AFG3L2", "AHCYL1", "AK2", "AK4", "AKT2", "ALG1", "ALYREF", "ANKFY1", "ANKLE2", "AP1M1", "AP2S1", "AP3M1", "AP3S1", "ARCN1", "ASCC3", "ATAD3A", "ATP13A1", "ATP1A1", "ATP2C1", "BAG5", "BSG", "CALM3", "CALU", "CBX3", "CD47", "CERS1", "CETN2", "CIRBP", "CISD1", "CLCN3", "CLCN7", "CLSTN3", "CNNM3", "CNNM4", "COPZ1", "CPNE8", "CPT1A", "CSE1L", "CTPS2", "CTSB", "CYB5B", "DHCR24", "DNAJA2", "DNM2", "DPM1", "DSC3", "EBP", "EEA1", "EGFR", "EHD4", "ELMOD2", "EMD", "ENDOD1", "ENPP1", "EPHA7", "ERAP2", "ERGIC3", "ERLIN1", "ESYT2", "ETFDH", "EWSR1", "EXOSC2", "FKBP14", "FKBP7", "FKBP9", "FLAD1", "FLOT1", "FLOT2", "FMR1", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR2", "G3BP2", "GALNT1", "GALNT2", "GGA2", "GLB1L2", "GM2A", "GNG5", "GPAM", "GPAT4", "GPRASP2", "GTF2E1", "HEXA", "HGS", "HLA-B", "HLA-C", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPUL2", "HSD17B4", "HSP90AA1", "HSP90B1", "HTRA2", "IDH2", "IGF2BP2", "IPO8", "ITM2C", "KCTD12", "KCTD5", "KDM1B", "KHDRBS3", "KHSRP", "KIF1B", "L2HGDH", "LEMD3", "LETM1", "LGALS3BP", "LMAN1", "LMNB1", "LMNB2", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LYRM2", "MAK16", "MCM4", "MCM6", "MCUB", "MFN1", "MICU1", "MICU2", "MOSPD2", "MPP5", "MPP6", "MRC2", "MRPL43", "MRPL48", "MSMO1", "MTR", "MTX3", "NACC1", "NDUFB9", "NEFL", "NEFM", "NENF", "NISCH", "NONO", "NOVA2", "NPEPPS", "NSUN2", "NUCB2", "OPA1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PANK4", "PAXBP1", "PDCD6IP", "PDIA4", "PDIA6", "PGRMC1", "PGRMC2", "PHB", "PHB2", "PLD3", "PSME2", "PSPC1", "PTBP2", "PTPN23", "PTPRF", "PUF60", "RABGAP1", "RALY", "RBFOX2", "RBM10", "RBM14", "RBM3", "RBM4", "RBM5", "RBMX", "RBMXL1", "RCN2", "REPS1", "RHOT2", "RNPS1", "RPL26", "RTN2", "RTN3", "RUFY1", "SAMHD1", "SCP2", "SDHB", "SEC23B", "SEC63", "SEL1L", "SFPQ", "SLC16A1", "SLIT2", "SMNDC1", "SNAP29", "SNRPA", "SNX2", "SNX27", "SNX5", "SNX6", "SPAG9", "SPNS1", "SPTAN1", "SPTBN2", "SQSTM1", "SRSF1", "SRSF3", "SRSF4", "SRSF7", "STARD3", "STARD3NL", "STOM", "STOML2", "STX10", "STX3", "STX5", "STX6", "STX7", "SUN1", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAF15", "TARBP1", "TDRKH", "TFIP11", "TIA1", "TIAL1", "TIMM44", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TOM1", "TPBG", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM21", "TRIM26", "TUBGCP2", "TXNDC5", "U2AF2", "UBE4B", "UNC119B", "UQCRC2", "USP15", "USP7", "VAPA", "VIM", "YKT6", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZCCHC3"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6bc77b3f5c84d1db75e9b908ed2b0fcaab0b6f4d --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..fe5e48dc53dc7222a31f507a23f720f3ed6b8027 --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:423670eda3b797a0656a19d8b7816e8f1c33eab24b97ceac8cb4e75888dca25a +size 185711 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..26c19af7758438ae984653258563fba4d71a6510 --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Small GTPase [IPR001806]", "2": "14-3-3 protein [IPR000308]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..8a204e8e5b02b51baa5463cee75edd13cd3287b6 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8ea1c126ad4d95f60ce100db1a454c2ec1772ba19cc31c39cb6b4453062b42d7 +size 131040 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..fb0cfc0270c8fa5b206714de1d14929711f8f1ac --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ca9446ea4b0697cbd9ef90fc8e09eac51282b1d26a0e03141c758e56d7be12bf +size 138671 diff --git a/interpro_family/basic/plot_2.png b/interpro_family/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..708135933271b6ce04711bb3a57ffde640fe0d7a --- /dev/null +++ b/interpro_family/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9c1c6b40912343c783f644114cddf77da09457e0947e42583baf1fbb2193f1ac +size 139793 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c26c4036c130782e960a37f936f912535ab937fe --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3aadb390b2dce12fda8083798f6ccab0b171c759dad5004a9c8c3c1e2888c202 +size 1063483 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0d223723779c0b4fae21ad383af9f911e158cedd --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transmembrane emp24 domain-containing protein [IPR015720] 4 5 2.5293928122342586 0.0114260068407543 2.6432038834951457 5.099514563106796 0.3626508447128717 0.2724944971681708 1.287119696753696 0.8431907483703972 1.4713835809049645 0.2794327521776852 0.2214576049043232 1.0 0.075113296023457 0.1775366954381628 0.0003311660608568 +Major facilitator superfamily [IPR011701] 2 5 2.3735115686865047 0.0176198410751546 1.900485436893204 4.145631067961165 1.0239318262629833 0.2378354197978781 1.3191273068698348 1.552684909115802 1.329586452483978 0.2573287434106264 0.5283863001864543 1.0 1.0 0.4439075633632242 0.1088149775417643 +Mitochondrial carrier protein [IPR002067] 9 11 2.203298741563527 0.0275736996229398 5.686893203883495 11.07766990291262 0.8032246115450145 0.31892620527414 3.2338505495684404 1.5403272908315857 1.3918146051602212 0.3274613788058813 0.4653827497861043 1.0 1.0 1.0 0.2539261987860491 +Syntaxin [IPR045242] 4 7 2.1173190114090885 0.0342327824695878 2.674757281553398 5.815533980582524 0.7134969984167514 0.3462495636510407 1.4434464182805606 1.4295601388514203 1.142372356309129 0.3001529293380739 0.0674209136026369 1.0 0.1277572387780678 0.0435926191526008 0.0037486095651754 +P-type ATPase [IPR001757] 3 6 2.006584755689639 0.0447938958400222 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.4978685671145173 1.0 1.0 0.4160065505344545 0.2906426697670494 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d023a9cf66792940ef1ea9d1d1fd4764323f460a --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 2585, + "title": "Average number of proteins per term", + "value": 1.2893617021276595 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1b44671e858fcf880420aa9504690d0c852305c1 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..45c25fdde92bd592acac411dc4612e00c9fa6abf --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,146 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.9982243267238828 4.178716716838638 2.9315856539646745e-05 0.0729822816718373 0.000187114788037 2 O60830 1 +ER lumen protein retaining receptor [IPR000133] 0.9952648712636876 4.165294637411708 3.109507189025251e-05 0.0772362264812816 0.000192181430887 2 P24390 1 +Tetraspanin/Peripherin [IPR018499] 0.9931932524415508 4.155886145014982 3.2402916714247e-05 0.0803507179607393 0.0001955178121166 2 O60637 1 +Tetraspanin, animals [IPR000301] 0.9931932524415508 4.155886145014982 3.2402916714247e-05 0.0803507179607393 0.0001955178121166 2 O60637 1 +Haem oxygenase-like [IPR016053] 0.9884581237052384 4.134340525064857 3.559753356729978e-05 0.0879142435617551 0.0002035832395386 2 P30519 1 +Haem oxygenase [IPR002051] 0.9884581237052384 4.134340525064857 3.559753356729978e-05 0.0879142435617551 0.0002035832395386 2 P30519 1 +Mitochondrial carrier UCP-like [IPR002030] 0.9878662326131992 4.1316433478322505 3.601789658391752e-05 0.0889048481262603 0.0002050798737212 2 Q9H2D1 1 +Palmitoyl protein thioesterase [IPR002472] 0.9831311038768868 4.110033986392665 3.956008880212636e-05 0.0972095861786938 0.0002139389739612 2 P50897 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.976620301864457 4.080227888392884 4.499157010440235e-05 0.1097970647653727 0.0002260168446333 2 Q9Y487 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.976620301864457 4.080227888392884 4.499157010440235e-05 0.1097970647653727 0.0002260168446333 2 Q9Y487 1 +CD36 family [IPR002159] 0.9736608464042622 4.066643745957304 4.7695070153785935e-05 0.1159968885806278 0.0002330657019802 2 Q14108 1 +Mpv17/PMP22 [IPR007248] 0.9644865344776564 4.024389032126617 5.7123421085991666e-05 0.1372827357388222 0.0002596013247522 2 Q9NR77 1 +Integral membrane protein 2 [IPR040145] 0.944362237348328 3.9309278997994506 8.461864745479275e-05 0.1964761880017771 0.0003380822313302 2 Q9NQX7 1 +Peroxisomal acyl-coenzyme A oxidase [IPR034171] 0.9419946729801724 3.9198616066090968 8.859983161046969e-05 0.2047038447318318 0.0003458714710449 2 O15254 1 +Acyl-CoA oxidase [IPR012258] 0.9419946729801724 3.9198616066090968 8.859983161046969e-05 0.2047038447318318 0.0003458714710449 2 O15254 1 +Sulfotransferase [IPR005331] 0.9381473808819184 3.901846674795281 9.54616200947722e-05 0.2186874890722181 0.0003634289955007 2 Q8NCH0 1 +Peptidase A22B, signal peptide peptidase [IPR007369] 0.9340041432376452 3.8824011745223057 0.0001034300557987 0.2346182286095537 0.0003863680552596 2 Q8TCT9 1 +Presenilin/signal peptide peptidase [IPR006639] 0.9340041432376452 3.8824011745223057 0.0001034300557987 0.2346182286095537 0.0003863680552596 2 Q8TCT9 1 +Cytochrome P450 [IPR001128] 0.9322284699615272 3.8740531011870742 0.0001070400732414 0.2417282128072793 0.0003941575346569 2 Q16850 1 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.9298609055933712 3.8629089509389702 0.000112044776811 0.2514759729384633 0.0004039550182099 2 Q9BTY2 1 +Glycoside hydrolase, family 29 [IPR000933] 0.9298609055933712 3.8629089509389702 0.000112044776811 0.2514759729384633 0.0004039550182099 2 Q9BTY2 1 +Derlin [IPR007599] 0.9236460491269608 3.8335824241853502 0.0001262904571137 0.2785422404603754 0.0004358536142227 2 Q9BUN8 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.923054158034922 3.830783874374155 0.0001277356689437 0.2812328274870745 0.0004379266634212 2 O96005 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.923054158034922 3.830783874374155 0.0001277356689437 0.2812328274870745 0.0004379266634212 2 O96005 1 +Isocitrate dehydrogenase NADP-dependent [IPR004790] 0.9183190292986094 3.808360560697651 0.0001398911944685 0.3034697349803593 0.0004672076714486 2 P48735 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.9091447173720046 3.7647375725011463 0.0001667240882374 0.3501525913720036 0.0005268725771318 2 Q5VW38 1 +Calcium uptake protein 1/2/3 [IPR039800] 0.8887244746966565 3.6667857459366022 0.0002456184243404 0.4700653670828426 0.0007000260495259 2 Q9BPX6 1 +Beta-galactosidase 1-like [IPR026283] 0.878958271678012 3.6195142888690848 0.000295156513306 0.5337774614236884 0.0008082410878136 2 Q8IW92 1 +Glycoside hydrolase, family 35 [IPR001944] 0.878958271678012 3.6195142888690848 0.000295156513306 0.5337774614236884 0.0008082410878136 2 Q8IW92 1 +Golgi phosphoprotein 3-like [IPR008628] 0.8736312518496605 3.5936120730748673 0.0003261252773885 0.5696564084578694 0.0008700039649631 2 Q9H4A5 1 +Endoplasmic reticulum vesicle transporter [IPR045888] 0.8733353063036422 3.592170606118514 0.0003279350336662 0.5716656041175328 0.0008734026812748 2 Q9Y282 1 +HnRNP R/Q splicing factor [IPR006535] 0.872151524119563 3.586402146092756 0.0003352717927862 0.5797152844094173 0.0008870804343423 2 O60506 1 +Glycoside hydrolase family 47 [IPR001382] 0.8718555785735445 3.5849593825121535 0.0003371306689843 0.5817306659555024 0.0008901764855204 2 P33908 1 +Porin, eukaryotic type [IPR001925] 0.9478981645944308 3.581339209087271 0.0003418374907002 0.5867906774772172 0.0008984307230581 3 P45880,P21796 2 +Prefoldin beta-like [IPR002777] 0.8691920686593677 3.571962813909166 0.0003543157300414 0.5999110815586876 0.0009223929418305 2 O15212 1 +Prolyl 4-hydroxylase [IPR045054] 0.8564664101805293 3.509575425911525 0.0004488227408609 0.6866602540041082 0.0011123746741377 2 P13674 1 +TAF15/EWS/TLS family [IPR034870] 0.9283599763173472 3.4927588620644237 0.0004780579927339 0.7094778310800378 0.0011647313018069 3 P35637,Q92804 2 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.928063943161633 3.4914091978951616 0.0004804797541608 0.7112917590514528 0.0011683556551647 3 P10619,Q9HB40 2 +Phosphatidyl serine synthase [IPR004277] 0.8443326427937272 3.449633329741995 0.0005613484491584 0.7657797052466013 0.0013324937934569 2 Q9BVG9 1 +Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434] 0.8384137318733368 3.4202293341384453 0.0006256836445495 0.801684963687793 0.0014518781159429 2 Q9H0P0 1 +Ancient conserved domain protein family [IPR045095] 0.8357502219591609 3.4069621349070593 0.000656902395256 0.8170698104315124 0.0015080752146864 2 Q8NE01 1 +Chloride channel, voltage gated [IPR001807] 0.8342704942290634 3.3995819313572606 0.0006748895683159 0.825386182685864 0.0015384387425897 2 P51790 1 +Histidine phosphatase superfamily, clade-2 [IPR000560] 0.9013908806066208 3.3688608126527777 0.0007547953415145 0.8579935338993967 0.0016762422317999 3 Q9NPH0 1 +Lysosome-associated membrane glycoprotein [IPR002000] 0.8215448357502237 3.335828848130437 0.0008504550412573 0.889126087125661 0.0018445486947771 2 P11279 1 +Tumour protein D52 [IPR007327] 0.8185853802900285 3.3209292401082053 0.0008971828059014 0.9017518204349976 0.0019151259729605 2 P55327 1 +Nonaspanin (TM9SF) [IPR004240] 0.8869153345174701 3.301560473118662 0.0009614860602991 0.9168107454035554 0.002028931808876 3 Q99805,Q9HD45 2 +Prenylated rab acceptor PRA1 [IPR004895] 0.8135543060076966 3.295535836921605 0.0009823417333223 0.921181020495428 0.0020645149436083 2 O75915 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.8129624149156576 3.2925430535509124 0.0009928569510655 0.9232966706126348 0.002079371491441 2 Q9NVI7 1 +Oligosaccharyl transferase, STT3 subunit [IPR003674] 0.8102989050014818 3.2790616073394685 0.0010415289561431 0.9323735031434088 0.0021569881233723 2 P46977 1 +Beta-hexosaminidase [IPR025705] 0.7972773009766232 3.2128220751674084 0.0013143768681074 0.9666233614452192 0.0025893295174552 2 P06865 1 +Heterogeneous nuclear ribonucleoprotein C [IPR017347] 0.7878070435039977 3.164299730586728 0.0015545660868203 0.9820771730282182 0.0029767061736523 2 P07910 1 +Glycosyl transferase, family 8 [IPR002495] 0.7824800236756466 3.136875550834098 0.0017075859098341 0.9879402595367576 0.0032102615104881 2 Q68CQ7 1 +MCU family [IPR039055] 0.7795205682154509 3.1215990367196276 0.0017987173644535 0.9904753408407486 0.0033378925966349 2 Q9NWR8 1 +Acyltransferase ChoActase/COT/CPT [IPR000542] 0.7753773305711777 3.100162633875612 0.0019341441033688 0.9932930024114832 0.003536564591609 2 P50416 1 +Cytochrome c oxidase subunit VII [IPR039297] 0.7741935483870999 3.0940273507038145 0.0019745928209919 0.9939601044804692 0.0035920636469136 2 P14406 1 +Cytochrome c oxidase subunit VIIa, metazoa [IPR003177] 0.7741935483870999 3.0940273507038145 0.0019745928209919 0.9939601044804692 0.0035920636469136 2 P14406 1 +SCAMP [IPR007273] 0.841918294849028 3.088669678111134 0.0020105484627122 0.994497206843608 0.0036446478093345 3 O15127,O15126 2 +TB2/DP1/HVA22-related protein [IPR004345] 0.8407341622261706 3.082990104483001 0.0020493196930833 0.9950229949316268 0.0037019506684977 3 Q9H6H4,Q00765 2 +Molecular chaperone regulator BAG [IPR039773] 0.7703462562888459 3.074055032673328 0.0021117047458996 0.9957656630876952 0.003793437642912 2 Q9UL15 1 +Membrane bound O-acyl transferase, MBOAT [IPR004299] 0.768866528558748 3.0663600413123024 0.0021668222420248 0.9963290790813716 0.0038843519387199 2 Q96N66 1 +Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238] 0.8288928359976209 3.025971832194549 0.0024783538967374 0.998362356248284 0.0043611605330607 3 O60220,Q9Y5J9 2 +Prolyl 3-hydroxylase [IPR039575] 0.7608759988162207 3.0246784278049264 0.0024889760975523 0.9984068204831495 0.0043738974929795 2 Q32P28 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.8277934748260662 3.0206575627601797 0.0025222643836846 0.998538497019062 0.0044143895950066 3 P28072 1 +Sorting nexin-5/6/32 [IPR014637] 0.7593962710861231 3.0169356805394956 0.0025534398547335 0.9986519330057628 0.0044598932597879 2 Q9Y5X3 1 +Bcl2-like [IPR002475] 0.8247483718176392 3.0059192419254313 0.002647793096171 0.9989443754011356 0.0045936544655047 3 Q07820,Q9BXK5 2 +Bcl-2 family [IPR026298] 0.8247483718176392 3.0059192419254313 0.002647793096171 0.9989443754011356 0.0045936544655047 3 Q07820,Q9BXK5 2 +Sodium/potassium-transporting ATPase subunit beta [IPR000402] 0.757028706717967 3.004531657754652 0.0026599007620642 0.9989769881911158 0.0046084741755603 2 P05026 1 +E3 ubiquitin-protein ligase, SMURF1 type [IPR024928] 0.7561408700799084 2.999875181416238 0.0027009026245079 0.999080130662017 0.0046606163213263 2 Q96PU5 1 +Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708] 0.7531814146197131 2.984333976251145 0.0028419638397259 0.9993618489561767 0.0048652162421797 2 Q8N8Q8 1 +Small GTPase superfamily, SAR1-type [IPR006687] 0.746966558153303 2.9515988267976465 0.0031613336368665 0.9997211933491676 0.0053030807600908 2 Q9NR31 1 +Eukaryotic porin/Tom40 [IPR027246] 0.8762709104185928 2.928480630424927 0.0034062305504045 0.9998522717652676 0.0056388553290908 4 P45880,P21796 2 +Peptidase, FtsH [IPR005936] 0.7416395383249516 2.923433195990935 0.0034619450319559 0.9998721502033926 0.0057140808307164 2 Q9Y4W6 1 +Aminopeptidase N-type [IPR034016] 0.8694107195735827 2.897247467907772 0.0037645267678543 0.9999416857848968 0.0061203155313858 4 P55786,Q6P179,Q9UIQ6 3 +CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131] 0.7309854986682485 2.866803369803754 0.0041464054381159 0.9999783551111432 0.0066254766723063 2 Q9NZ45 1 +G-protein, gamma subunit [IPR001770] 0.7244746966558191 2.831998689716729 0.0046258038224202 0.9999937657075296 0.0072647040589042 2 P63218 1 +Tricarboxylate/iron carrier [IPR004686] 0.785079928952027 2.811413611100922 0.0049324334262952 0.999997188772379 0.0076395089316795 3 Q6P4A7,Q96NB2 2 +SUN domain-containing protein 1-5 [IPR045119] 0.7126368748150378 2.7683296060084825 0.005634444014416 0.9999995464795652 0.0085458322690716 2 O94901 1 +Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349] 0.6978395975140615 2.6880318793358637 0.0071874534396048 0.9999999920226432 0.0104337193434736 2 P27361 1 +Adenosylhomocysteinase-like [IPR000043] 0.6975436519680418 2.68641779577407 0.0072222717454841 0.9999999927140442 0.0104650069854689 2 O43865 1 +Translin family [IPR002848] 0.6948801420538662 2.6718766245331276 0.0075428375226618 0.9999999968382586 0.0108504368369954 2 Q99598 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.6928085232317297 2.660548855795568 0.0078013408383017 0.9999999983875972 0.0111540188423728 2 O75880 1 +Copper chaperone SCO1/SenC [IPR003782] 0.6928085232317297 2.660548855795568 0.0078013408383017 0.9999999983875972 0.0111540188423728 2 O75880 1 +Prohibitin [IPR000163] 0.687481503403378 2.631347914933012 0.0085046922344913 0.9999999997421516 0.01195466526708 2 Q99623 1 +Tropomyosin [IPR000533] 0.7489638839549992 2.63016673504039 0.0085342999819915 0.9999999997613068 0.0119897638333956 3 P09493,P67936 2 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.6836342113051241 2.610193325028139 0.0090491067451028 0.9999999999376602 0.0126034164526351 2 P11940 1 +Copine [IPR045052] 0.7438317973008529 2.6040822526445155 0.0092120645811273 0.9999999999592494 0.0127753148831621 3 Q86YQ8 1 +Proteasome activator PA28 [IPR009077] 0.7412572751722831 2.5909657147567917 0.0095707025975679 0.9999999999840158 0.013173730678761 3 Q9UL46 1 +Synaptobrevin [IPR001388] 0.6738680082864799 2.5562471567625007 0.0105807935300652 0.9999999999988568 0.0143501318337978 2 P51809 1 +Transmembrane emp24 domain-containing protein [IPR015720] 0.8415284360189529 2.5293928122342586 0.0114260068407543 0.9999999999998744 0.0153275701522314 5 Q15363,Q9BVK6,P49755,Q9Y3A6 4 +Integral membrane protein EMC3/TMCO1-like [IPR002809] 0.6463450725066637 2.402301600011877 0.0162922696305993 1.0 0.0206752660751592 2 Q9P0I2 1 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.7036708111308363 2.397077371617355 0.0165264336095645 1.0 0.0209108325407363 3 P12235,P12236 2 +Mitochondrial Rho GTPase [IPR021181] 0.6448653447765662 2.3939443538449536 0.0166682774024784 1.0 0.0210696807263602 2 Q8IXI1 1 +Flotillin family [IPR027705] 0.6424977804084098 2.380555589159094 0.0172865526289789 1.0 0.0217343086312794 2 Q14254 1 +Major facilitator superfamily [IPR011701] 0.8073049919776228 2.3735115686865047 0.0176198410751546 1.0 0.0220781818610154 5 P53985,Q9H2V7 2 +Erlin1/2 [IPR033294] 0.6383545427641364 2.35707436906902 0.0184195575595826 1.0 0.0228916136016929 2 O75477 1 +E3 ubiquitin ligase Bre1 [IPR013956] 0.6300680674755897 2.309917507110105 0.0208927216240131 1.0 0.0255234808119441 2 Q5VTR2 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.7355641101569391 2.2628196630414865 0.0236468082863914 1.0 0.0284708893434195 4 P55209,Q99733,Q01105 3 +Mitochondrial carrier protein [IPR002067] 0.6970632542247585 2.203298741563527 0.0275736996229398 1.0 0.0324728991003642 11 P12235,P12236,Q9BQT8,Q6NUK1,Q9H936,O43808,O75746,Q9UJS0,Q8TBP6 9 +Spectrin, beta subunit [IPR016343] 0.6114234980763597 2.2028668032758145 0.027604138010234 1.0 0.0324791519146359 2 O15020 1 +Syntaxin [IPR045242] 0.7772072975084021 2.1173190114090885 0.0342327824695878 1.0 0.0392076839538699 7 O60499,Q13190,O43752,O15400 4 +P-type ATPase [IPR001757] 0.7748375973755848 2.006584755689639 0.0447938958400222 1.0 0.0496749123751426 6 Q9HD20,P98194,P05023 3 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.612196566015396 1.90636067410109 0.0566034272472257 1.0 0.060587933513076 3 P51116,Q06787 2 +Tight junction protein ZO [IPR005417] 0.558745190884884 1.8934105654988864 0.0583032914586545 1.0 0.0621501065652049 2 Q07157 1 +Prefoldin alpha-like [IPR004127] 0.5543060076945908 1.8668748085771771 0.0619190725296987 1.0 0.0653309397915393 2 Q99471 1 +Vacuolar protein-sorting protein Bro1-like [IPR045251] 0.5525303344184739 1.8562413636432544 0.0634191627074669 1.0 0.0667774075758867 2 Q9H3S7 1 +THRAP3/BCLAF1 family [IPR029199] 0.5504587155963371 1.8438219642794256 0.0652090906308404 1.0 0.0684668965396923 2 Q9Y2W1 1 +Protein transport protein Sec23 [IPR037364] 0.5489789878662394 1.834941972438521 0.0665142877824205 1.0 0.0696675177947962 2 Q15437 1 +JmjC domain-containing [IPR039994] 0.5380290026635168 1.7690009400085134 0.0768937177162003 1.0 0.0803436783736369 2 Q9H6W3 1 +KH domain-containing BBP-like [IPR045071] 0.6347539219640743 1.752811485920388 0.079634370931521 1.0 0.0831400843529813 4 Q07666,O75525 2 +Plakophilin/Delta catenin [IPR028435] 0.5720540946121662 1.6829354917397676 0.0923875799671853 1.0 0.09622155286671 3 O00192 1 +Adaptor protein complex, sigma subunit [IPR016635] 0.5226398342705014 1.675670064329758 0.0938028365806942 1.0 0.0976561951514678 2 Q92572 1 +Gamma-tubulin complex component protein [IPR007259] 0.5193844332642867 1.6558332801269482 0.0977555861484735 1.0 0.1016076357835963 2 Q9BSJ2 1 +Paraneoplastic encephalomyelitis antigen [IPR002343] 0.513465522343896 1.619686618872188 0.105299612072133 1.0 0.1093609872263816 2 Q15717 1 +Sister chromatid cohesion protein Pds5 [IPR039776] 0.4948209529446659 1.5051986100726136 0.1322730224178949 1.0 0.1370993436047548 2 Q29RF7 1 +Small GTPase [IPR001806] 0.420639884947542 1.5040560271083514 0.1325669412855024 1.0 0.1373489151194483 35 Q15907,P51148,P61020,Q8IXI1,Q15382,P20339,P51151,P61026,P61106,Q969Q5,Q9H0U4,P51149,P20340,Q9BZG1,P61019 15 +Proteasome B-type subunit [IPR023333] 0.6434962453815168 1.476133390356379 0.1399080867124535 1.0 0.1447228508009974 7 P20618,P28072,P28074,P49721 4 +NSF attachment protein [IPR000744] 0.489493933116312 1.4723293293783424 0.1409319668618467 1.0 0.1457236537351495 2 Q99747 1 +Dynein family light intermediate chain [IPR022780] 0.4856466410180605 1.4485513730155362 0.1474629094039092 1.0 0.1523547645120325 2 O43237 1 +Dynein 1 light intermediate chain [IPR008467] 0.4856466410180605 1.4485513730155362 0.1474629094039092 1.0 0.1523547645120325 2 O43237 1 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.6549359092342563 1.4480172376224665 0.1476122297986726 1.0 0.1524481078823686 6 Q6P179,Q9UIQ6,P55786 3 +Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237] 0.480023675643688 1.4137444414499112 0.157436951604684 1.0 0.162335269205468 2 Q9UBW8 1 +Adenylate kinase 3/4, mitochondrial [IPR028586] 0.4755844924533945 1.3862232402087018 0.1656787471422991 1.0 0.170697314213967 2 P27144 1 +Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756] 0.452796685409892 1.2445037434601405 0.2133142224753199 1.0 0.2191642548087051 2 Q8TB37 1 +Mrp/NBP35 ATP-binding protein [IPR019591] 0.452796685409892 1.2445037434601405 0.2133142224753199 1.0 0.2191642548087051 2 Q8TB37 1 +CPSF6/7 family [IPR034772] 0.4385912992009539 1.1559617704231318 0.2476967944919619 1.0 0.2540857991117942 2 Q8N684 1 +Adenylate kinase subfamily [IPR006259] 0.4757252812315008 1.132511480897292 0.2574194603582267 1.0 0.2638498433885868 3 P54819,P27144 2 +Ras GTPase-activating protein-binding protein [IPR039539] 0.4297129328203691 1.100638688812491 0.2710539401459919 1.0 0.2771655202837773 2 Q9UN86 1 +Mini-chromosome maintenance protein [IPR031327] 0.5511173795097929 0.950494527332202 0.3418610333485175 1.0 0.3486038545190996 6 Q14566,P33991 2 +CTP synthase [IPR004468] 0.4004143237644341 0.9189094158107276 0.3581429545350945 1.0 0.3649190135881826 2 Q9NRF8 1 +Chaperone DnaJ [IPR012724] 0.4381957788590276 0.9171517297058368 0.3590631370818675 1.0 0.3657124544352355 3 O60884 1 +Calreticulin/calnexin [IPR001580] 0.4319123741859104 0.8813993006966623 0.3781017360397611 1.0 0.3843464363597257 3 P27824,O14967 2 +Protein disulphide isomerase [IPR005792] 0.4114860864416758 0.766286825538246 0.4435056555542536 1.0 0.4495929880814688 3 P13667,P07237 2 +Annexin [IPR001464] 0.4697631358326972 0.7161584847481479 0.4738934943566915 1.0 0.4802095973783016 5 P20073 1 +RNA (C5-cytosine) methyltransferase [IPR023267] 0.3897524406361425 0.6464938837746047 0.5179595568496664 1.0 0.5244518035473512 3 Q08J23 1 +Heat shock protein Hsp90 family [IPR001404] 0.4216760438258672 0.628744940200858 0.5295160516318691 1.0 0.5357334612400712 4 P07900,Q12931,P14625 3 +UBAP2/protein lingerer [IPR022166] 0.3495116898490754 0.6128488069997403 0.5399763154712083 1.0 0.5454625930023733 2 Q14157 1 +ClpA/B family [IPR001270] 0.3438887244747056 0.5804511615255458 0.5616104123747854 1.0 0.566652192033107 2 Q9H078 1 +Ubiquitin conjugation factor E4 [IPR045132] 0.3427049422906263 0.5736804620750109 0.5661840519574255 1.0 0.5710440009012661 2 O95155 1 +Adenylate kinase/UMP-CMP kinase [IPR000850] 0.4318720379146832 0.5357309951737191 0.5921444789224499 1.0 0.5969943361991158 5 Q9UIJ7,P54819,P00568,P27144 4 +Small GTPase superfamily, ARF/SAR type [IPR006689] 0.4156755931769937 0.4694621332609136 0.6387393453646595 1.0 0.6429677600341296 9 Q8N8L6 1 +Aminotransferase class-III [IPR005814] 0.3154779520568296 0.4237009204409915 0.6717839438223161 1.0 0.6754420438664672 2 P80404 1 +HnRNP-L/PTB [IPR006536] 0.32563647128478 0.3234329558770134 0.7463673744153048 1.0 0.749265888490704 3 P14866,Q9UKA9 2 +Glutathione Transferase family [IPR040079] 0.358743563823084 0.2993353152787519 0.7646842114455321 1.0 0.767058085598254 11 Q5HYI7 1 +YTH domain containing protein [IPR045168] 0.2773830669034863 0.1325004977080905 0.8945884293819328 1.0 0.8959748508145279 3 Q7Z739,Q9Y5A9 2 +14-3-3 protein [IPR000308] 0.3333333333333356 0.0716513779866233 0.942879351393718 1.0 0.9436094167064504 6 P62258,Q04917,P31946,P61981,P63104 5 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..45cf755afddf3f89a42bb6baf0315c346aed3f73 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 [IPR039210]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "4-aminobutyrate aminotransferase, eukaryotic [IPR004631]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease 1 [IPR016494]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5'-deoxynucleotidase YfbR/HDDC2 [IPR039356]", "5-formyltetrahydrofolate cyclo-ligase [IPR002698]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchor protein 9/Pericentrin [IPR028745]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABT1/Esf2 [IPR039119]", "ADF/Cofilin [IPR017904]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AMP deaminase 2 [IPR029749]", "AMP deaminase [IPR006329]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "ARMET-like [IPR045333]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP12, ATP synthase F1-assembly protein [IPR011419]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Acetoacetyl-CoA synthase [IPR005914]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Actin-related protein 6 [IPR030054]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active regulator of SIRT1 [IPR023262]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenomatous polyposis coli (APC) family [IPR026818]", "Adenomatous polyposis coli [IPR026836]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-catulin 1 [IPR030045]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid beta precursor protein binding family B member 1/2/3 [IPR039576]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAX [IPR026304]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Armadillo-type fold containing protein ARMC8/Vid28 [IPR038739]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arylesterase [IPR002640]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Atypical kinase COQ8B [IPR034638]", "Aurora kinase B [IPR028772]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 9 [IPR007241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "BTB-kelch protein [IPR017096]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-adducin [IPR027773]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [IPR013109]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bromodomain-containing protein 8 [IPR038002]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 10 [IPR039740]", "CCR4-NOT transcription complex subunit 11 [IPR019312]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDC50/LEM3 family [IPR005045]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calsyntenin [IPR026914]", "Calumenin [IPR027239]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cationic amino acid transport permease [IPR004755]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle control protein 50A [IPR030351]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein Cdc6/18 [IPR016314]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Cellular repressor of E1A-stimulated genes (CREG) [IPR014631]", "Centrin 2 [IPR037629]", "Centrosomal protein of 135kDa [IPR026732]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 55kDa [IPR038926]", "Ceramide glucosyltransferase [IPR025993]", "Cerebellar degeneration-related protein 2 [IPR026079]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin complexes subunit BAP18 [IPR037931]", "Chromatin modification-related protein Eaf6 [IPR015418]", "Chromatin modification-related protein Eaf7/MRGBP [IPR012423]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homolog 2 [IPR042796]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Clusterin [IPR016016]", "Clusterin-like [IPR000753]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 127 [IPR034607]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 93 [IPR039116]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-7 [IPR031223]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme [IPR000277]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic protein NCK [IPR017304]", "Cytoplasmic protein NCK1 [IPR028526]", "Cytoplasmic protein NCK2 [IPR028524]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA replication/checkpoint protein [IPR021110]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IA [IPR000380]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-binding protein SATB1/SATB2 [IPR039673]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrogenase/reductase SDR member 4-like [IPR029511]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dimethylallyltransferase [IPR039657]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Dishevelled family [IPR008339]", "Dishevelled-2 [IPR008341]", "Dishevelled-related protein [IPR015506]", "Disks large 1-like [IPR016313]", "Divalent ion tolerance protein, CutA [IPR004323]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dymeclin [IPR019142]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Ecd family [IPR010770]", "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [IPR029890]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosome-associated-trafficking regulator 1 [IPR026757]", "Endosulphine [IPR006760]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exosome-associated factor Rrp47/DNA strand repair C1D [IPR011082]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Eyes absent family [IPR028472]", "Eyes absent homologue 4 [IPR028478]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FUN14 [IPR007014]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Formin-binding protein 1-like [IPR030116]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase 2-like [IPR045130]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GPCR-associated sorting protein [IPR043374]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI-anchor transamidase [IPR028361]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GRIP1-associated protein 1 [IPR026204]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "Galactokinase [IPR000705]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycoside hydrolase, family 79 [IPR005199]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycosyltransferase 61 [IPR007657]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "Guided entry of tail-anchored proteins factor CAMLG [IPR016719]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HEXIM [IPR024872]", "HIRA-interacting protein 3 [IPR037647]", "HMG domain-containing protein 4 [IPR042477]", "HMG-CoA lyase [IPR043594]", "HS1-associating protein X-1 [IPR017248]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase SMUBP-2/Hcs1-like [IPR004483]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Hermansky-Pudlak syndrome 3 protein [IPR017216]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "High mobility group protein HMGN3 [IPR031073]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase EZH1/2-like [IPR045318]", "Histone-lysine N-methyltransferase EZH1/EZH2 [IPR021654]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "Histone-lysine N-methyltransferase, SET [IPR017155]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "IPP transferase [IPR018022]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 1,4,5-trisphosphate receptor-interacting protein [IPR024797]", "Inositol 1,4,5-trisphosphate receptor-interacting protein family [IPR026250]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 12 [IPR039053]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 7 [IPR033060]", "Integrator complex subunit 9 [IPR027074]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intermembrane space protein MIX23 [IPR019171]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intracellular lipid binding protein [IPR031259]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intraflagellar transport protein 52 homolog [IPR039975]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Kelch-like ECH-associated protein 1 [IPR030563]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine zipper protein 1 [IPR026734]", "Leucine zipper putative tumor suppressor [IPR045329]", "Leucine zipper putative tumour suppressor 2 [IPR028597]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat flightless-interacting protein 1/2 [IPR019139]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Lon protease [IPR027065]", "Lon protease homologue 2, peroxisomal [IPR027501]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MIOS/Sea4 [IPR037593]", "MKRN-like [IPR045072]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Magnesium transporter protein 1 [IPR006844]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannosyltransferase ALG2 [IPR027054]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D1 [IPR030083]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Menin [IPR007747]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthiotransferase [IPR005839]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microsomal glutathione S-transferase 1-like [IPR040162]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein Mtm1-like [IPR045315]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial outer membrane transport complex protein, metaxin [IPR017410]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple PDZ domain protein [IPR032078]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin [IPR030561]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyl phosphatidylinositol deacetylase-related [IPR003737]", "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase [IPR039516]", "N-acetyltransferase Ard1-like [IPR045047]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B/Dorsal [IPR000451]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Nck-associated protein 1 [IPR019137]", "Nectin-2 [IPR033318]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurabin-2 [IPR029921]", "Neurabin-like family [IPR043446]", "Neural cell adhesion [IPR009138]", "Neural cell adhesion molecule 1 [IPR033019]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neuropilin [IPR014648]", "Neuropilin-1 [IPR027146]", "Neutral amino acid SLC6 transporter [IPR002438]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear factor related to kappa-B-binding protein [IPR024867]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase 7 [IPR011410]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC family [IPR037898]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "ORC ubiquitin ligase 1 [IPR039209]", "Occludin [IPR002958]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 2 [IPR007220]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "P-type ATPase, subfamily IV [IPR006539]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic antigen Ma [IPR026523]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Partner of Y14 and mago [IPR039333]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxisome membrane protein, Pex16 [IPR013919]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phospholipid-transporting ATPase IG [IPR030363]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pianissimo family [IPR028268]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Pre-rRNA-processing protein TSR2 [IPR019398]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Progesterone-induced-blocking factor 1 [IPR026205]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase 3 [IPR039839]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM210A/B-like [IPR045866]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein MMS22-like [IPR042320]", "Protein Mon2-like [IPR026829]", "Protein NDRG3 [IPR030692]", "Protein Nucling [IPR030227]", "Protein OS-9-like [IPR045149]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SMG8 [IPR028802]", "Protein SMG9 [IPR039177]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein flightless-1 [IPR029919]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF3512 [IPR021900]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein strawberry notch [IPR026741]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein virilizer [IPR026736]", "Protein wntless [IPR009551]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Proto-oncogene c-Rel [IPR030505]", "Protocadherin-19 [IPR030716]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA methyltransferase [IPR003750]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxamine 5'-phosphate oxidase [IPR000659]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "Quinone oxidoreductase-like protein 1 [IPR042633]", "RAB11-binding protein RELCH [IPR040362]", "RAD3/XPD family [IPR001945]", "RFT1 [IPR007594]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein Fox-1 [IPR017325]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase Rpc34 [IPR007832]", "RNA polymerase Rpc34-like [IPR016049]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding protein Nova-1 [IPR033086]", "RNA-binding protein Nova-2 [IPR033087]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab-like protein 6 [IPR040385]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3 [IPR037872]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rabaptin [IPR003914]", "Rabaptin-5 [IPR029880]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "Ragulator complex protein LAMTOR3 [IPR015019]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab-23 [IPR034114]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Regulatory associated protein of TOR [IPR004083]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulon-4-interacting protein 1 [IPR037397]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retinoid X receptor/HNF4 [IPR000003]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease P protein subunit Rpp29/RNP1 [IPR002730]", "Ribonuclease P protein subunit Rpp38 [IPR042848]", "Ribonuclease P/MRP subunit Rpp29 [IPR016848]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA small subunit methyltransferase H [IPR002903]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis factor [IPR031389]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L55, mitochondrial [IPR018615]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "Root UVB sensitive family [IPR006968]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAP30-binding protein [IPR012479]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SH3 and PX domain-containing protein 2B [IPR030512]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SHC-transforming protein 1 [IPR029586]", "SIKE family [IPR008555]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SPRY domain-containing protein 7 [IPR035766]", "SSNA1 family [IPR033362]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sarcolemmal membrane-associated protein [IPR030498]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 8 [IPR030646]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase MARK3 [IPR033628]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase RAC alpha [IPR039027]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sialidase family [IPR026856]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Slowmo/Ups family [IPR037365]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium/solute symporter [IPR001734]", "Sodium:dicarboxylate symporter [IPR001991]", "Sodium:neurotransmitter symporter [IPR000175]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sororin protein [IPR018605]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Sperm-associated antigen 5 [IPR028728]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 3B subunit 5/RDS3 complex subunit 10 [IPR009846]", "Splicing factor 3B, subunit 5 [IPR017089]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntaxin-3 [IPR031186]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TB2/DP1/HVA22-related protein [IPR004345]", "TCF25/Rqc1 [IPR006994]", "TE2IP/Rap1 [IPR039595]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TRAPP III complex, Trs85 [IPR024420]", "TREX component Tex1/THOC3 [IPR040132]", "TRIC channel [IPR007866]", "Tankyrase 1-binding protein-like [IPR040006]", "Target of Myb protein 1 [IPR014645]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomere-associated protein Rif1 [IPR028566]", "Teneurin-3/4 [IPR027691]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 21A/21B [IPR040364]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "Tetratricopeptide repeat protein TTC27/Emw1 [IPR044244]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "The WD repeat Cdc20/Fizzy family [IPR033010]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 16 [IPR040090]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A [IPR030549]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TFIID component TAF4 [IPR045144]", "Transcription initiation factor TFIID subunit 7 [IPR037817]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulator TACO1-like [IPR002876]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery-associated protein 16 [IPR021346]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 11 [IPR026120]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 177 [IPR026620]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Trimethyllysine dioxygenase [IPR012776]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "TspO/MBR-related protein [IPR004307]", "Tuberin [IPR003913]", "Tuberin/Ral GTPase-activating protein subunit alpha [IPR027107]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine protein kinase, EGF/ERB/XmrK receptor [IPR016245]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm1/8 [IPR044642]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UAP56-interacting factor [IPR009782]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronic acid decarboxylase [IPR044516]", "UDP-glucuronosyl/UDP-glucosyltransferase [IPR002213]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubinuclein-2 [IPR026943]", "Ubiquilin-1/2 [IPR028430]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquinone biosynthesis protein COQ9 [IPR012762]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein C17orf80 [IPR037694]", "Uncharacterized protein C19orf47-like [IPR039161]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vasodilator-stimulated phosphoprotein [IPR034367]", "Vasodilator-stimulated phosphoprotein/ENA/VASP-like [IPR017354]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle transport protein, Use1 [IPR019150]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "Vps52 [IPR007258]", "WASH complex subunit 7 [IPR027307]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat HIR1 [IPR031120]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat-containing protein 11 [IPR039694]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 73 [IPR042795]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC-type and RNA-binding motif-containing protein 1 [IPR044598]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger ZZ-type and EF-hand domain-containing protein 1 [IPR040099]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "cAMP response element binding (CREB) protein [IPR001630]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "cAMP-responsive element-binding protein 1 [IPR029802]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA isopentenyltransferase, eukaryotes [IPR030666]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-specific 2-thiouridylase [IPR004506]", "tRNAHis guanylyltransferase Thg1 [IPR007537]"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANKLE2", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEX1", "API5", "APLP2", "APOL2", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARID1A", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC6", "ARMC8", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD3A", "ATAD3B", "ATG4B", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATXN2L", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG4", "BAG5", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD7", "BRD8", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C12orf43", "C12orf73", "C14orf2", "C16orf58", "C17orf80", "C19orf25", "C19orf47", "C19orf70", "C1D", "C1QBP", "C1orf123", "C1orf35", "C2CD2L", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf59", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CAST", "CBL", "CBR1", "CBX2", "CBX3", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC8", "CCDC86", "CCDC93", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC37", "CDC40", "CDC42", "CDC45", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDK5RAP3", "CDK6", "CDKAL1", "CDR2L", "CDS2", "CEBPZ", "CELF2", "CENPB", "CEP135", "CEP170", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHERP", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CIAPIN1", "CIP2A", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG7", "COIL", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CREG1", "CRNKL1", "CRTAP", "CRYZL1", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DECR1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX29", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EFHD1", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM210B", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GCAT", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GM2A", "GMFB", "GNA13", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GRIPAP1", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDHD2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN3", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPS3", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IGHMBP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO4", "IPO5", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMF2", "LNPEP", "LONP1", "LONP2", "LRPAP1", "LRPPRC", "LRRC47", "LRRFIP2", "LSG1", "LSM12", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARK3", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METAP1", "METTL15", "MFAP1", "MFF", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGST1", "MGST2", "MGST3", "MICU1", "MICU2", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKRN2", "MLEC", "MMAB", "MMS19", "MMS22L", "MOB4", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPI", "MPST", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MTX3", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA10", "NAA15", "NAA40", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCK1", "NCK2", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NHP2", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRP1", "NSA2", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT21", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PAWR", "PAXBP1", "PBDC1", "PBRM1", "PC", "PCBD1", "PCDH19", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDP1", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PEBP1", "PECR", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKMYT1", "PKP2", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIE", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP1R9B", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM5", "RBM6", "RBM8A", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REL", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF40", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTFDC1", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARS", "SARS2", "SART1", "SATB2", "SBDS", "SBNO1", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B5", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIKE1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLK", "SLMAP", "SLTM", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMG8", "SMG9", "SMPD4", "SMU1", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPRYD7", "SPTBN1", "SPTBN2", "SQLE", "SRFBP1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STARD3", "STAT1", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TARSL2", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TECR", "TENM3", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TK1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM177", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMX2", "TNKS1BP1", "TNPO1", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPT1", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM28", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TST", "TSTA3", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UACA", "UAP1", "UBA1", "UBA2", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBN2", "UBQLN1", "UBR4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USE1", "USMG5", "USP10", "USP14", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS52", "VPS53", "VTA1", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WBP11", "WBP2", "WDR11", "WDR12", "WDR18", "WDR33", "WDR41", "WDR46", "WDR73", "WDR74", "WDR82", "WDR91", "WFS1", "WLS", "WTAP", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YEATS2", "YEATS4", "YIF1A", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H14", "ZC3H7B", "ZCCHC3", "ZCRB1", "ZFYVE16", "ZMPSTE24", "ZMYND8", "ZNF326", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZZEF1"], "leading_proteins": ["ABAT", "ACOX3", "ACP6", "AFG3L2", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "ANXA7", "AP3S1", 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sha256:f077b86ecab4765daeb1a73829cb09775e6665f6bada56cf895d2bccd3d2f819 +size 376114 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..291ff556c7865da7316bbb29b2e3eedd32f596c3 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,12 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier domain superfamily [IPR023395] 14 21 3.2536089466079976 0.001139490218085 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0001363014485767 0.0007818203448131 0.0058560324261939 0.002055769463525 6.527780116797021e-05 +Glycoside hydrolase superfamily [IPR017853] 10 17 2.950158294331291 0.0031761115730013 7.094660194174757 15.565533980582524 0.5992585613623983 0.1928722204186086 2.565315823223627 1.245604487832095 1.9386029676344616 0.2695693578719223 9.760868426110005e-06 1.0 0.0260710687649276 2.8484663686520977e-05 1.2856393626457652e-08 +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 49 132 2.3409387963601187 0.0192353200870507 41.78155339805825 126.65533980582524 0.1165973051667422 0.543214063567699 13.579176287791377 6.87987395678373 1.6323826073741117 0.3875195330163939 0.022357027479976 1.0 0.8634038105452405 0.056003069988558 0.0008219571738365 +Zinc finger, RanBP2-type superfamily [IPR036443] 4 9 2.294609664777456 0.0217555039000301 3.2742718446601944 8.616504854368932 0.6239078002715212 0.4100405386528319 1.463145369641179 0.7330740021954685 1.0299872364022182 0.3121093098016552 0.0003636238723029 1.0 0.1854358412925483 0.0001164002838048 0.0028394369313259 +Glycosyl hydrolase, all-beta [IPR013780] 3 8 2.072221188026134 0.0382448183257733 3.628640776699029 7.919902912621359 0.108448733903935 0.2677010542317815 1.6191976609214136 0.9906808437954988 1.5895506376095985 0.2857304479214345 0.0065763731833925 1.0 1.0 0.0379575415698398 0.0027834726260547 +RNA-binding domain superfamily [IPR035979] 47 133 2.0574370076841166 0.0396442083991581 42.40291262135922 128.71601941747574 0.0615554024640467 0.5527296641044032 14.098054374547743 6.713949807605091 1.6556654950344032 0.3906506493803742 0.0208667599350938 1.0 0.8606572512943966 0.0532242531221608 0.000721867035513 +Alpha/Beta hydrolase fold [IPR029058] 10 23 2.0556423433449837 0.0398170031792295 7.793689320388349 25.487864077669904 0.3803730368869525 0.1931612116461074 2.8504230618688027 2.5849355029363217 1.9090082785106757 0.2379814650369476 5.4658489612813245e-06 0.0040269256520789 0.0004676667677534 5.028282040848048e-07 7.978277875658614e-05 +SNARE [IPR010989] 4 6 2.054729234948855 0.0399051645632431 2.4854368932038833 5.364077669902913 0.7966086592831925 0.3585374753437345 1.5079985943563208 1.7302199405020957 1.098385457365192 0.3157194502762394 0.0854309101739854 1.0 0.144637307685789 0.0557098434243155 0.00630824692371 +P-type ATPase, A domain superfamily [IPR008250] 3 6 2.006584755689639 0.0447938958400222 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.4978685671145173 1.0 1.0 0.4160065505344545 0.2906426697670494 +P-type ATPase, cytoplasmic domain N [IPR023299] 3 6 2.006584755689639 0.0447938958400222 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.4978685671145173 1.0 1.0 0.4160065505344545 0.2906426697670494 +P-type ATPase, transmembrane domain superfamily [IPR023298] 3 6 2.006584755689639 0.0447938958400222 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.5133658415211507 1.0 1.0 0.4301270919610729 0.3089323218960526 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..79636954dee280086896e15ce3f1e15c7ec9a761 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 1018, + "title": "Average number of proteins per term", + "value": 4.8870333988212185 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6f724fb865a02e4ad7d2f3cecdb18ea532de39f6 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4bec0e49f8830956dcbf5908e01f5fc50825ab0a --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,124 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tetraspanin, EC2 domain superfamily [IPR008952] 0.9931932524415508 4.155886145014982 3.2402916714247e-05 0.0324485755947874 0.0004004890937151 2 O60637 1 +Haem oxygenase-like, multi-helical [IPR016084] 0.9884581237052384 4.134340525064857 3.559753356729978e-05 0.0355901645246979 0.0004071717884439 2 P30519 1 +Cytochrome P450 superfamily [IPR036396] 0.9322284699615272 3.8740531011870742 0.0001070400732414 0.1032450358590391 0.0007313207688578 2 Q16850 1 +Rhomboid-like superfamily [IPR035952] 0.9236460491269608 3.8335824241853502 0.0001262904571137 0.1206495809095239 0.0007839249106208 2 Q9BUN8 1 +Alkaline-phosphatase-like, core domain superfamily [IPR017850] 0.8907960935187935 3.676777379824307 0.0002361989992532 0.2137488299317342 0.0011672358312609 2 P15586 1 +Golgi phosphoprotein 3-like domain superfamily [IPR038261] 0.8736312518496605 3.5936120730748673 0.0003261252773885 0.2825483211896458 0.0014887692035045 2 Q9H4A5 1 +Seven-hairpin glycosidases [IPR036026] 0.8718555785735445 3.5849593825121535 0.0003371306689843 0.2905440607865369 0.0015118899604671 2 P33908 1 +Chloride channel, core [IPR014743] 0.8342704942290634 3.3995819313572606 0.0006748895683159 0.4970525171349548 0.0025493548753677 2 P51790 1 +FAD-binding, type PCMH-like superfamily [IPR036318] 0.8333826575910049 3.3951505319561024 0.000685908769598 0.5026666267711882 0.0025493548753677 2 Q15392 1 +FAD-binding, type PCMH, subdomain 2 [IPR016169] 0.8333826575910049 3.3951505319561024 0.000685908769598 0.5026666267711882 0.0025493548753677 2 Q15392 1 +Mitochondrial carrier domain superfamily [IPR023395] 0.7184800626575154 3.2536089466079976 0.001139490218085 0.6867214190873032 0.0037540486796457 21 Q70HW3,Q9H2D1,P12236,Q02978,Q9Y6C9,Q9Y619,Q9BQT8,Q9NZJ7,Q6NUK1,Q9BSK2,Q9UBX3,Q9H936,O43808,O43772 14 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.7916543356022516 3.1840475720210653 0.0014523114244291 0.7722547633251694 0.0044531717773158 2 A6NIH7 1 +Beta-hexosaminidase-like, domain 2 [IPR029018] 0.8528182526482155 3.140761886470309 0.0016850897472979 0.8203721930425935 0.0049214395519546 3 P54802 1 +Choline/Carnitine o-acyltransferase, domain 2 [IPR042231] 0.7753773305711777 3.100162633875612 0.0019341441033688 0.8606637609557426 0.0053650100741949 2 P50416 1 +Cytochrome c oxidase, subunit VIIa superfamily [IPR036539] 0.7741935483870999 3.0940273507038145 0.0019745928209919 0.8662954424695288 0.0054181549643392 2 P14406 1 +BAG domain superfamily [IPR036533] 0.7703462562888459 3.074055032673328 0.0021117047458996 0.8837472308253287 0.0057288415415793 2 Q9UL15 1 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.8374777975133186 3.0673504806201164 0.0021596547415498 0.8892971818203806 0.0058138585186737 3 P10321,P01889 2 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.8374777975133186 3.0673504806201164 0.0021596547415498 0.8892971818203806 0.0058138585186737 3 P10321,P01889 2 +Bcl-2-like superfamily [IPR036834] 0.8247483718176392 3.0059192419254313 0.002647793096171 0.9327291441862846 0.0068067004340962 3 Q07820,Q9BXK5 2 +Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702] 0.757028706717967 3.004531657754652 0.0026599007620642 0.9335553883659278 0.0068206019541093 2 P05026 1 +Regulatory factor, effector binding domain superfamily [IPR011256] 0.7555489789878692 2.996769356211492 0.0027285706759594 0.9380533290778056 0.0069442123703167 2 Q9Y6I9 1 +Glycoside hydrolase superfamily [IPR017853] 0.7353359736467893 2.950158294331291 0.0031761115730013 0.9607744559670348 0.0078668651613512 17 P04062,P04066,P16278,P10253,O60502,Q9BTY2,P06865,Q8IW92,P54802,P06280 10 +Porin domain superfamily [IPR023614] 0.8762709104185928 2.928480630424927 0.0034062305504045 0.9689905031129852 0.0082586663723612 4 P45880,P21796 2 +Peptidase M41-like [IPR037219] 0.7416395383249516 2.923433195990935 0.0034619450319559 0.9707060584083592 0.008371163996511 2 Q9Y4W6 1 +DNA/RNA non-specific endonuclease superfamily [IPR044929] 0.7998815867377108 2.8845408168090345 0.0039198494098777 0.9816522457107292 0.0091772771294498 3 P22413,O94919 2 +His-Me finger superfamily [IPR044925] 0.7998815867377108 2.8845408168090345 0.0039198494098777 0.9816522457107292 0.0091772771294498 3 P22413,O94919 2 +MitoNEET, CDGSH iron-sulfur domain [IPR042216] 0.7309854986682485 2.866803369803754 0.0041464054381159 0.9854449326561544 0.0095715209433152 2 Q9NZ45 1 +G-protein gamma-like domain superfamily [IPR036284] 0.7244746966558191 2.831998689716729 0.0046258038224202 0.9910847644793528 0.0104645962027196 2 P63218 1 +Carboxypeptidase-like, regulatory domain superfamily [IPR008969] 0.7167801124593114 2.7906709819251994 0.0052598910449446 0.995339818508887 0.011664033629724 2 O75976 1 +Tim10-like domain superfamily [IPR035427] 0.8291382884216717 2.711427233937351 0.0066994243685443 0.9989330611721025 0.0138405751889245 4 Q9Y5J7,O60220,Q9Y5J9 3 +ESCRT assembly domain [IPR037202] 0.7010949985202762 2.705765687437289 0.0068147110701954 0.9990519676375236 0.0139424531889879 2 Q9H9H4 1 +Fibronectin type II domain superfamily [IPR036943] 0.7637411548797794 2.7048138608204697 0.0068342673293761 0.9990707818161172 0.0139424531889879 3 Q9UBV2 1 +Kringle-like fold [IPR013806] 0.7637411548797794 2.7048138608204697 0.0068342673293761 0.9990707818161172 0.0139424531889879 3 Q9UBV2 1 +Prefoldin [IPR009053] 0.8259491564363725 2.6965295523715587 0.007006618014308 0.9992212672659097 0.0141522562273126 4 O15212 1 +Adenosylhomocysteinase-like superfamily [IPR042172] 0.6975436519680418 2.68641779577407 0.0072222717454841 0.9993757447528492 0.0144289348461672 2 O43865 1 +START-like domain superfamily [IPR023393] 0.8237249359763998 2.6861232794351846 0.0072286412294158 0.9993798086817912 0.0144289348461672 4 O95433,Q14849 2 +Translin, C-terminal [IPR016069] 0.6948801420538662 2.6718766245331276 0.0075428375226618 0.9995506526218688 0.0148810244148638 2 Q99598 1 +Translin superfamily [IPR036081] 0.6948801420538662 2.6718766245331276 0.0075428375226618 0.9995506526218688 0.0148810244148638 2 Q99598 1 +Translin, N-terminal [IPR016068] 0.6948801420538662 2.6718766245331276 0.0075428375226618 0.9995506526218688 0.0148810244148638 2 Q99598 1 +GOLD domain superfamily [IPR036598] 0.8063369854900743 2.6043141173998365 0.0092058341918364 0.9999185028252976 0.0174842149389728 4 Q15363,Q13445,Q9Y3A6 3 +Proteasome activator superfamily [IPR036252] 0.7412572751722831 2.5909657147567917 0.0095707025975679 0.9999439854139244 0.0178477439953752 3 Q9UL46 1 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.7412572751722831 2.5909657147567917 0.0095707025975679 0.9999439854139244 0.0178477439953752 3 Q9UL46 1 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.7412572751722831 2.5909657147567917 0.0095707025975679 0.9999439854139244 0.0178477439953752 3 Q9UL46 1 +Lamin tail domain superfamily [IPR036415] 0.7229709101140189 2.4971981474601592 0.0125178987629488 0.9999973037591674 0.0223565279661086 3 Q03252 1 +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 0.3733073951012552 2.3409387963601187 0.0192353200870507 0.9999999974118824 0.0319438105197678 132 P09012,Q9BWF3,P98179,Q15287,P26368,P55795,Q86V81,Q16629,P35637,P84103,P62995,P11940,O43251,P22626,Q16540,Q8WXF1,Q13151,Q53F19,O43390,Q99729,Q86U42,Q15233,O60506,P31943,P38159,P07910,Q9Y6M1,P52272,Q92804,Q9UKM9,Q01085,P98175,P51991,Q13595,Q14011,P52597,P31483,P09651,Q96PK6,Q96E39,Q9UN86,Q14103,P31942,Q9UHX1,Q01844,P23246,O14979,P52756,Q07955 49 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.7663127014310357 2.294609664777456 0.0217555039000301 0.9999999998114326 0.0354063426248175 9 P52756,P35637,Q92804,P98175 4 +NAP-like superfamily [IPR037231] 0.7355641101569391 2.2628196630414865 0.0236468082863914 0.9999999999737048 0.0381496843669516 4 P55209,Q99733,Q01105 3 +Ricin B-like lectins [IPR035992] 0.7263843648208406 2.217513477988969 0.0265880230717407 0.999999999998781 0.0422915741984877 4 Q10471,Q10472,Q9UBG0 3 +Glycosyl hydrolase, all-beta [IPR013780] 0.7449403005726932 2.072221188026134 0.0382448183257733 1.0 0.0573390648831181 8 Q9BTY2,P04066,P06280 3 +RNA-binding domain superfamily [IPR035979] 0.3553640736337132 2.0574370076841166 0.0396442083991581 1.0 0.0589165024092598 133 P09012,Q9BWF3,P98179,Q15287,P26368,P55795,Q86V81,Q16629,P35637,P84103,P62995,P11940,O43251,P22626,Q8WXF1,Q13151,O43390,Q99729,Q86U42,Q15233,O60506,P31943,P38159,P07910,Q9Y6M1,P52272,Q92804,Q9UKM9,Q01085,P98175,P51991,Q13595,Q14011,P52597,P31483,P09651,Q96PK6,Q96E39,Q9UN86,Q14103,P31942,Q9UHX1,Q01844,P23246,O14979,P52756,Q07955 47 +Alpha/Beta hydrolase fold [IPR029058] 0.5346953883324507 2.0556423433449833 0.0398170031792295 1.0 0.0590010323674755 23 P10619,Q9NUJ1,Q9H6V9,P50897,Q96JX3,P07099,Q9HB40,Q9UMR5,P42785,Q8N2K0 10 +SNARE [IPR010989] 0.7854685617853587 2.054729234948855 0.0399051645632431 1.0 0.0590457231473568 6 O60499,Q13190,O43752,O15400 4 +P-type ATPase, A domain superfamily [IPR008250] 0.7748375973755848 2.006584755689639 0.0447938958400222 1.0 0.0645894985341963 6 Q9HD20,P98194,P05023 3 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.7748375973755848 2.006584755689639 0.0447938958400222 1.0 0.0645894985341963 6 Q9HD20,P98194,P05023 3 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.7748375973755848 2.006584755689639 0.0447938958400222 1.0 0.0645894985341963 6 Q9HD20,P98194,P05023 3 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.7337059404899926 1.9129118146008577 0.0557593428190625 1.0 0.0766032536974436 7 O15173,Q9UMX5,O00264,O43169 4 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.6059798697454104 1.8720631477449212 0.061197867666672 1.0 0.0822977929784307 3 Q9UEY8,P35611 2 +LEM/LEM-like domain superfamily [IPR011015] 0.7340623298374231 1.8197067818968689 0.0688036699805563 1.0 0.090963813039229 6 P50402,Q86XL3 2 +Lambda repressor-like, DNA-binding domain superfamily [IPR010982] 0.5389168393015755 1.7743623342579604 0.0760032359391773 1.0 0.0997052760129929 2 O60869 1 +MoaB/Mog-like domain superfamily [IPR036425] 0.5294465818289504 1.7170428920415828 0.0859713353220361 1.0 0.1120599479613736 2 Q8NFF5 1 +Acyl-CoA binding protein superfamily [IPR035984] 0.5693306546100935 1.66761679612558 0.0953918218459337 1.0 0.1226122154534855 3 Q5T8D3 1 +Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241] 0.5193844332642867 1.6558332801269482 0.0977555861484735 1.0 0.1253339882860782 2 Q9BSJ2 1 +MAN1, winged-helix domain [IPR041885] 0.5161290322580719 1.6359651667073782 0.1018468778277419 1.0 0.1301198048225132 2 Q9Y2U8 1 +Cobalamin-binding domain superfamily [IPR036724] 0.512873631251857 1.61606641863766 0.1060799537968657 1.0 0.1346899683214582 2 Q99707 1 +Band 7/SPFH domain superfamily [IPR036013] 0.6394900681885712 1.5478098975942485 0.1216680728204988 1.0 0.1527226857352254 8 P35232,Q99623,Q9UJZ1,O75477,P27105,O75955,Q14254 7 +Ribosomal protein L37ae/L37e [IPR011331] 0.5007398638650564 1.5416413124067232 0.123160780572995 1.0 0.154406003230676 2 P61513 1 +Cadherin-like superfamily [IPR015919] 0.6722643194306391 1.5303029901533434 0.1259417484968206 1.0 0.1576982779455884 6 Q14574,Q9BQT9 2 +Histidine phosphatase superfamily [IPR029033] 0.6709630680238808 1.5241389129708818 0.1274740138727168 1.0 0.1594208183322183 6 Q9NPH0,P11117 2 +Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438] 0.4930452796685489 1.4942494012462662 0.1351104448364459 1.0 0.1671232476834775 2 Q53H12 1 +NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064] 0.4930452796685489 1.4942494012462662 0.1351104448364459 1.0 0.1671232476834775 2 Q53H12 1 +p53-like tetramerisation domain superfamily [IPR036674] 0.4900858242083536 1.4759846369708634 0.1399480165297899 1.0 0.1728969427516094 2 P04637 1 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.6549359092342563 1.4480172376224665 0.1476122297986726 1.0 0.1812656814656799 6 Q6P179,Q9UIQ6,P55786 3 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.6549359092342563 1.4480172376224665 0.1476122297986726 1.0 0.1812656814656799 6 Q6P179,Q9UIQ6,P55786 3 +K Homology domain, type 1 superfamily [IPR036612] 0.4353066706318103 1.4066492410033555 0.159531424075255 1.0 0.1940298562826877 28 Q9Y6M1,P61978,Q96I24,Q9UNW9,Q96AE4,Q9Y2W6,Q92945,O75525 8 +Immunoglobulin-like domain superfamily [IPR036179] 0.5254876598115047 1.4028776658405122 0.1606533219402117 1.0 0.1951611953879899 14 P35613,P10321,P01889,Q08722,P10586 5 +Adenylate kinase, active site lid domain superfamily [IPR036193] 0.4755844924533945 1.3862232402087018 0.1656787471422991 1.0 0.2010261794885107 2 P27144 1 +EF-hand domain pair [IPR011992] 0.3674594465840595 1.3850206792773976 0.1660461442374865 1.0 0.2012321128973348 57 Q9NWM8,Q14257,O43852,O95202,Q8IYU8,Q9BPX6,O95302,Q9H223,Q9Y680,P80303,Q96D71,P41208,P0DP25 13 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.6013118203178641 1.3770336085205728 0.1685018572493906 1.0 0.2037231480758665 5 O60476,P33908 2 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.4521766516843603 1.36857000633834 0.1711337249834073 1.0 0.2064148483804604 20 Q9H9P8,Q9UHG3,Q96CU9,O95831 4 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.3257676348187125 1.2221368108109856 0.2216558947000855 1.0 0.2602603238808386 90 O75153,Q9UBV2,O00231,P30260,Q92791,Q6DKK2,Q5VZ89,P13674,O75718,Q5R3I4,Q6P2P2,Q32P28,Q96TC7,Q96DB5,Q9UJX3,Q9Y262,Q96EK5,Q9UGR2,O15460,Q9H0B6,O43242,Q96BR5 22 +PX domain superfamily [IPR036871] 0.5139833969739249 1.2153224774442273 0.2242431222424588 1.0 0.2629948138742201 12 Q9UNH7,Q9Y5X3,O60749,Q9Y2I1,Q96L92 5 +BRO1 domain superfamily [IPR038499] 0.4748371817643563 1.1273960290393763 0.2595750772434553 1.0 0.3009651806763525 3 Q8WUM4,Q9H3S7 2 +FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156] 0.4974951350928168 1.0248743449513118 0.305422481243274 1.0 0.3485651187283105 4 O95831 1 +Rho GTPase activation protein [IPR008936] 0.5445294826010013 0.9847328269455614 0.3247553236429024 1.0 0.3683072429365551 7 O15031,Q9H0H5,Q14C86 3 +PapD-like superfamily [IPR008962] 0.449970396684436 0.9844549918404628 0.3248918508418728 1.0 0.3683072429365551 3 Q8NHP6,Q9P0L0 2 +Growth factor receptor cysteine-rich domain superfamily [IPR009030] 0.5168505367599278 0.9500592934528442 0.3420821253881354 1.0 0.3865034446671719 5 P00533,Q15375 2 +PUA domain superfamily [IPR036974] 0.4033737792246298 0.9371660754446108 0.3486731372147322 1.0 0.3935135850161834 2 Q9Y221 1 +Signal recognition particle, SRP9/SRP14 subunit [IPR009018] 0.4013021604024955 0.924383167203568 0.3552868555296444 1.0 0.400533797263763 2 P49458 1 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.4381957788590276 0.9171517297058368 0.3590631370818675 1.0 0.404343222952811 3 O60884 1 +Calreticulin/calnexin, P domain superfamily [IPR009033] 0.4319123741859104 0.8813993006966623 0.3781017360397611 1.0 0.4231475691206696 3 P27824,O14967 2 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.5208137989518438 0.8674936169096782 0.3856716076624442 1.0 0.430497474342509 7 P22695 1 +Immunoglobulin-like fold [IPR013783] 0.3455348951251329 0.7869119601871419 0.4313334056296942 1.0 0.4793639813657519 34 P35613,P10321,P01889,P08236,Q15375,Q08722,O15031,Q8IZA0,P10586 9 +AH/BAR domain superfamily [IPR027267] 0.4304422236226649 0.7562927593107285 0.4494736883801851 1.0 0.4973524073598135 13 P53365,Q9UNH7,Q9Y5X3,O60749,Q9UQB8 5 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.4966773716380429 0.7496009187508161 0.453495097326825 1.0 0.5001711907678308 7 A1L0T0,Q13423 2 +LDL receptor-like superfamily [IPR036055] 0.4412200177672409 0.7283939102174976 0.4663724900378985 1.0 0.5132618322795467 4 Q07954,P98164,P14314 3 +Annexin superfamily [IPR037104] 0.4697631358326972 0.7161584847481479 0.4738934943566915 1.0 0.5204137834467227 5 P20073 1 +MFS transporter superfamily [IPR036259] 0.456992076437169 0.6772913252510637 0.498221133722037 1.0 0.5465399936735277 9 P53985,Q9H2V7,Q16625,Q7L0J3 4 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.3579433380748402 0.6476600719344319 0.5172048344245956 1.0 0.5649297440388823 20 Q68CQ7,Q16739 2 +HSP90, C-terminal domain [IPR037196] 0.4216760438258672 0.628744940200858 0.5295160516318691 1.0 0.5752906516128524 4 P07900,Q12931,P14625 3 +AF1104-like superfamily [IPR036075] 0.351583308671212 0.62487861461398 0.532050729011007 1.0 0.5774281899074682 2 Q9NVE7 1 +HAD-like superfamily [IPR036412] 0.3531922453305088 0.6120931120993757 0.5404761544569869 1.0 0.5840814492964042 20 P16615,Q969T7,P05023,P98194,Q9HD20,Q3ZCQ8,Q9H0P0,Q9BSH5 8 +HAD superfamily [IPR023214] 0.3531922453305088 0.6120931120993757 0.5404761544569869 1.0 0.5840814492964042 20 P16615,Q969T7,P05023,P98194,Q9HD20,Q3ZCQ8,Q9H0P0,Q9BSH5 8 +Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930] 0.3468481799348996 0.5974548989849213 0.5502037099617376 1.0 0.5920796794302843 2 Q6YHK3 1 +Six-bladed beta-propeller, TolB-like [IPR011042] 0.4417432552623914 0.541227353997924 0.5883508855704662 1.0 0.62980147372317 8 P13798,Q07954,P98164,Q8NBF2,Q9HDC9,Q15165,Q9P273 7 +Ribosomal protein S10 domain superfamily [IPR036838] 0.3335306303640212 0.5218490304424658 0.6017754486613156 1.0 0.6421461286553661 2 Q96GC5 1 +AP-2 complex subunit mu, C-terminal superfamily [IPR036168] 0.3991708617115717 0.5176834424786756 0.6046791524273711 1.0 0.6444945462563522 4 Q9Y2T2,P48444,Q9BXS5 3 +Acyl-CoA N-acyltransferase [IPR016181] 0.4193930222844492 0.4875580265566193 0.6258629321880635 1.0 0.6622957016293646 9 O60502 1 +Alpha/beta knot methyltransferases [IPR029028] 0.3651919344957998 0.3606807865094238 0.7183380893932247 1.0 0.7492501793056382 4 Q13395 1 +tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026] 0.3651919344957998 0.3606807865094238 0.7183380893932247 1.0 0.7492501793056382 4 Q13395 1 +SCP2 sterol-binding domain superfamily [IPR036527] 0.3294849023090564 0.3409870631055401 0.733113320885675 1.0 0.7615401639404257 3 P22307,P51659 2 +Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100] 0.3822077355076195 0.3140181992903598 0.7535072163663357 1.0 0.7778916927583618 9 O15254 1 +Acyl-CoA dehydrogenase-like, C-terminal [IPR036250] 0.3822077355076195 0.3140181992903598 0.7535072163663357 1.0 0.7778916927583618 9 O15254 1 +NTF2-like domain superfamily [IPR032710] 0.3978566360374689 0.3049043666827734 0.7604389898971236 1.0 0.7835292426267932 7 Q13555,Q9BRJ2,O43615,Q9UN86 4 +Myosin S1 fragment, N-terminal [IPR008989] 0.3479419603198043 0.2875279123407428 0.7737081328488209 1.0 0.7955907871112118 4 Q7Z406,Q9UM54,P35580 3 +Longin-like domain superfamily [IPR011012] 0.3447920036923487 0.2505228535386942 0.8021830334915097 1.0 0.8215516379218882 12 O15498,P48444,Q92572,P51809 4 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.3853119707748186 0.229902284897061 0.8181677007905375 1.0 0.8320626567480192 6 P42892 1 +PDZ superfamily [IPR036034] 0.2879783833832763 0.1882676961856257 0.8506668072272279 1.0 0.8625286949774084 29 Q8N3R9,P57105,Q9NZW5,Q96L92,O43464 5 +Homeobox-like domain superfamily [IPR009057] 0.2910960773457074 0.144236774992017 0.8853135023094612 1.0 0.8958739019393951 19 Q96KC8 1 +L27 domain superfamily [IPR036892] 0.345465400172536 0.1383653299568307 0.8899516961056846 1.0 0.8996731148317645 8 Q9NZW5,Q8N3R9 2 +HotDog domain superfamily [IPR029069] 0.3273104265402735 0.1242656525425919 0.9011049417689788 1.0 0.9082424066542776 5 Q9NPJ3,O14734,Q9Y305,P51659 4 +GAT domain superfamily [IPR038425] 0.2593250444049662 0.0773428502645813 0.9383508033945492 1.0 0.9439141480787068 3 O60784,Q9UJY4 2 +14-3-3 domain superfamily [IPR036815] 0.3333333333333356 0.0716513779866233 0.942879351393718 1.0 0.9475332475012884 6 P62258,Q04917,P31946,P61981,P63104 5 +Concanavalin A-like lectin/glucanase domain superfamily [IPR013320] 0.2707665139698581 0.0614520698691979 0.9509991849221128 1.0 0.954750660996756 20 Q12907,Q9BQT9,Q1KMD3,Q9BUJ2,P49257 5 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..489b8aa3bacb0da6d6998949cae5457e31fbe88f --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "5-formyltetrahydrofolate cyclo-ligase-like domain superfamily [IPR024185]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "AN1-like Zinc finger [IPR035896]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "APC, N-terminal coiled-coil domain superfamily [IPR036149]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP12 orthogonal Bundle domain superfamily [IPR023335]", "ATP12, ATP synthase F1-assembly protein, N-terminal [IPR042272]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenomatous polyposis coli protein [IPR026831]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha-macroglobulin, receptor-binding domain superfamily [IPR036595]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Calycin [IPR012674]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DIX domain superfamily [IPR038207]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IA, central region, subdomain 1 [IPR013824]", "DNA topoisomerase, type IA, central region, subdomain 2 [IPR013825]", "DNA topoisomerase, type IA, central region, subdomain 3 [IPR013826]", "DNA topoisomerase, type IA, core domain [IPR023405]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Disintegrin domain superfamily [IPR036436]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "EYA domain superfamily [IPR038102]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GBBH-like, N-terminal domain superfamily [IPR038492]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrase-like, N-terminal [IPR017856]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kazal domain superfamily [IPR036058]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "Mitochondrial ribosomal protein L55 superfamily [IPR044884]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NFRKB winged helix-like domain superfamily [IPR038106]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Putative deacetylase LmbE-like domain superfamily [IPR024078]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Receptor L-domain superfamily [IPR036941]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease P/MRP subunit Rpp29 superfamily [IPR036980]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rof/RNase P-like [IPR023534]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily [IPR023397]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAS-6, N-terminal domain superfamily [IPR038558]", "SATB, CUTL domain superfamily [IPR038216]", "SATB, ULD domain superfamily [IPR038224]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Seven-hairpin glycosidases [IPR036026]", "Sialidase superfamily [IPR036278]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/glucose symporter superfamily [IPR038377]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Sodium:neurotransmitter symporter superfamily [IPR037272]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Somatomedin B-like domain superfamily [IPR036024]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfatase-modifying factor enzyme superfamily [IPR042095]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAFH/NHR1 domain superfamily [IPR037249]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "TTC5, OB fold domain superfamily [IPR038645]", "Talin, central domain superfamily [IPR036476]", "Taurine dioxygenase TauD-like superfamily [IPR042098]", "Tautomerase/MIF superfamily [IPR014347]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transcriptional regulator TACO1-like, domain 3 [IPR026564]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps53, C-terminal domain superfamily [IPR038260]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WIBG, N-terminal domain superfamily [IPR036348]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YebC-like [IPR029072]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "mRNA decapping protein 2, Box A domain superfamily [IPR036189]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "tRNAHis guanylyltransferase Thg1 superfamily [IPR038469]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATPAF2", "ATRX", "ATXN10", "AURKB", "BABAM1", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAS3", "BCAT2", "BCL2L13", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BROX", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C19orf47", "C1QBP", "C2CD2L", "C2CD5", "CAB39", "CACYBP", "CAD", "CADM1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC6", "CDC73", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP170", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHP1", "CHRAC1", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT2", "CNOT7", "CNOT9", "CNP", "COA7", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "COQ8B", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM120A", "FAM120B", "FAM129B", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNBP4", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLPH3", "GOLPH3L", "GOPC", "GORASP2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPRASP2", "GPS1", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH2", "INF2", "INTS1", "INTS11", "INTS12", "INTS14", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LACTB", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYN", "LYPLA1", "LZIC", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MED21", "MED25", "MEPCE", "METAP1", "METTL13", "METTL15", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDZ", "MPG", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL55", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCBP3", "NCDN", "NCK1", "NCK2", "NCKIPSD", "NCL", "NCOA5", "NDRG3", "NDUFA10", "NDUFA9", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEK9", "NELFE", "NENF", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PICALM", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA1", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REL", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RINT1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP25L", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPTOR", "RREB1", "RRM1", "RRM2", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SAAL1", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SATB2", "SBDS", "SBNO1", "SCAF11", "SCAF4", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERAC1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG9", "SMU1", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPOUT1", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX10", "STX12", "STX3", "STX5", "STX6", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF4", "TAGLN2", "TALDO1", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFRC", "THADA", "THG1L", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMA16", "TMED1", "TMED2", "TMED5", "TMEM14C", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC5", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WNK1", "WNK3", "WRAP53", "WRAP73", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZFR", "ZFYVE16", "ZMYND8", "ZNF280C", "ZNF281", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZZEF1"], "leading_proteins": ["ABHD10", "ABHD12", "ACBD5", "ACOT13", "ACOT8", "ACOT9", "ACOX3", "ACP2", "ACP6", "ADD1", "ADD3", "AFG3L2", "AGK", "AHCYL1", "AHSA1", "AIFM1", "AK4", "ALYREF", "ANAPC7", "ANKLE2", "ANXA7", "AP1M1", "AP3M1", "AP3S1", "APEH", "APMAP", "ARCN1", "ARFIP2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2C1", "BAG5", "BAIAP2", "BCL2L13", "BSG", "CALM3", "CALU", "CAMK2G", "CANX", "CD109", "CD47", "CDC27", "CETN2", "CIRBP", "CISD1", "CLCN3", "CLGN", "CLSTN3", "CLUH", "COA7", "COX7A2", "CPD", "CPT1A", "CRTAP", "CTSA", "CYB5B", "CYP51A1", "DENND4C", "DERL1", "DHCR24", "DNAJA2", "DNAJC1", "DSC3", "ECE1", "EDF1", "EGFR", "EHD4", "EIF3L", "EMD", "ENDOD1", "ENPP1", "EPHA7", "EPHX1", "ERAP2", "ERLIN1", "EWSR1", "FKBP14", "FKBP7", "FKBP9", "FLAD1", "FLOT1", "FLOT2", "FOXRED1", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "G3BP2", "GAA", "GALNT1", "GALNT2", "GAPVD1", "GBA", "GGA2", "GLA", "GLB1", "GLB1L2", "GLT8D1", "GNG5", "GNS", "GOLPH3L", "GUSB", "HDHD3", "HEXA", "HLA-B", "HLA-C", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPUL1", "HNRNPUL2", "HSD17B4", "HSP90AA1", "HSP90B1", "HTRA2", "IGF2BP2", "ILVBL", "KHDRBS3", "KHSRP", "KIAA0319L", "KIFBP", "KLC2", "L2HGDH", "LDAH", "LEMD3", "LETM1", "LMAN1", "LMAN2", "LMNB2", "LNPEP", "LRP1", "LRP2", "MAN1A1", "MAN1A2", "MCL1", "MGEA5", "MICU1", "MICU2", "MOSPD2", "MPP5", "MPP6", "MRC2", "MRPL23", "MRPL45", "MRPL48", "MTCH1", "MTCH2", "MTR", "MYH10", "MYH14", "MYO6", "NAGLU", "NAP1L1", "NAP1L4", "NCBP3", "NENF", "NHLRC2", "NIP7", "NISCH", "NNT", "NONO", "NOVA2", "NPEPPS", "NT5C3A", "NT5C3B", "NUCB2", "OCLN", "P3H1", "P3H4", "P4HA1", "P4HA2", "PABPC1", "PABPN1", "PANK4", "PCYOX1", "PDCD6IP", "PFDN6", "PGRMC1", "PGRMC2", "PHB", "PHB2", "PLXNB2", "PON2", "PPT1", "PPT2", "PRCP", "PRKCSH", "PRMT9", "PSMD11", "PSMD3", "PSME2", "PSPC1", "PTPN23", "PTPRF", "PUF60", "RACGAP1", "RALY", "RBFOX2", "RBM10", "RBM14", "RBM3", "RBM4", "RBM5", "RBMX", "RBMXL1", "RCN2", "REPS1", "RMDN1", "RMDN3", "RNPS1", "RPL37A", "SCP2", "SCPEP1", "SEL1L", "SERAC1", "SET", "SFPQ", "SLC16A1", "SLC25A10", "SLC25A11", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A6", "SNRPA", "SNX2", "SNX27", "SNX5", "SNX6", "SPNS1", "SRP9", "SRSF1", "SRSF3", "SRSF7", "STARD3", "STOM", "STOML2", "STX10", "STX5", "STX6", "STX7", "SV2A", "SYNCRIP", "SYNJ2BP", "TAF15", "TARBP1", "TDRKH", "TENM3", "TEX264", "TIA1", "TIAL1", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TMED1", "TMED2", "TMED5", "TOM1", "TP53", "TRA2A", "TRA2B", "TRAP1", "TSNAX", "TSPAN3", "TTC19", "TTC38", "TUBGCP2", "U2AF2", "UGCG", "UNC119B", "UQCRC2", "VAMP7", "VAPA", "VDAC1", "VDAC2", "VPS37B", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H7B"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..43f698bc28777e5ad981263151a781915563360d --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5cd3170de2da9ed905485ea5c6080a421760c70b527de59c7363fdc3a82530a8 +size 76064 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8f1efabccc776d80462400162c60e315879fa0e9 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +P-type ATPase, phosphorylation site [IPR018303] 3 6 2.006584755689639 0.0447938958400222 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.4978685671145173 1.0 1.0 0.4160065505344545 0.2906426697670494 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a1aee5b12c93618504e061b9a624c5b6bb786677 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 5, + "title": "Average number of proteins per term", + "value": 2.6 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4690951792e85b3c2f21253e78959a2d350ab24f --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..af97aa89f590f60ce1fb474872b14d616d7094ac --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.7748375973755848 2.006584755689639 0.0447938958400222 0.2047833848541077 0.0578807340806658 6 Q9HD20,P98194,P05023 3 +EGF-type aspartate/asparagine hydroxylation site [IPR000152] 0.4412200177672381 0.7283939102174816 0.4663724900379082 0.9567295857655164 0.4663724900379082 4 O94813,Q07954,P98164 3 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..021ba682f097a38cdd276bfdc9afe21205c16388 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Rapamycin-insensitive companion of mTOR, phosphorylation-site [IPR029259]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "EIF5A", "FASN", "LDLR", "LRP1", "LRP2", "RICTOR", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP1A1", "ATP2C1", "LRP1", "LRP2", "SLIT2"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a4e4af78a628e633664ac81cab25f5b4e6af2599 --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c70166e6759725c86d079d07ca87eeb6314034b9f9675c8e3c29b3233ba173b8 +size 184054 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..89347332fd727e794f5dc31a862dff01327a7f4e --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]", "1": "Tetratricopeptide repeat [IPR019734]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b86bc75cfa0e4977c501b1232bbe5fa458d15e34 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d54acd3b68aa03873c2b49b3903ec16f0f1898927a2182baae4520e71acf6cf1 +size 146156 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..65ce484ba7e8da4d41b6f70d161459cb239b4072 --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:af6489890b60296550c16966b5e0c7aa7e1ce7bbac776916e246481857f46f12 +size 150859 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..1407056ce50086e20680fac966ac96498692b935 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7bc619fc0ded6d1517e45b831e24a871bca6a2a31627e5046ba680e9a371975a +size 99967 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2e79a8ec6ebc006a5c589ad8f74b84feecfc4d0d --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 14 21 3.2536089466079976 0.001139490218085 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0001363014485767 0.0007818203448131 0.0058560324261939 0.002055769463525 6.527780116797021e-05 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..701141a41ab5d587e4e2fca988149306b9a62af9 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 82, + "title": "Average number of proteins per term", + "value": 5.548780487804878 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2d72996ab1bb091c49c88ebcde08b4fc19c52b1f --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2005e29d5acae684e4258e05257dc13fd629fdde --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Sel1-like repeat [IPR006597] 0.8893163657886954 3.669641765483611 0.000242890609212 0.0197223677032452 0.001106501664188 2 Q9UBV2 1 +Mitochondrial substrate/solute carrier [IPR018108] 0.7184800626575154 3.2536089466079976 0.001139490218085 0.0892542178752839 0.003114606596099 21 Q70HW3,Q9H2D1,P12236,Q02978,Q9Y6C9,Q9Y619,Q9BQT8,Q9NZJ7,Q6NUK1,Q9BSK2,Q9UBX3,Q9H936,O43808,O43772 14 +LDLR class B repeat [IPR000033] 0.4410894020130244 0.933657963969784 0.3504803551514592 0.9999999999999996 0.3991581822558286 3 Q07954,P98164 2 +Low-density lipoprotein (LDL) receptor class A repeat [IPR002172] 0.4412200177672409 0.7283939102174976 0.4663724900378985 1.0 0.5031913708303641 4 Q07954,P98164,P14314 3 +Annexin repeat [IPR018502] 0.4697631358326972 0.7161584847481479 0.4738934943566915 1.0 0.5046657991850481 5 P20073 1 +Tetratricopeptide repeat [IPR019734] 0.2537508187942043 0.0216483190563977 0.982728489516188 1.0 0.982728489516188 51 P13674,Q9UGR2,O15460,Q9H0B6,Q6P2P2,Q6DKK2,Q9UJX3 7 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9fc2736ea56911dc5a700c0df6114f6b6334804e --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Adenomatous polyposis coli (APC) repeat [IPR041257]", "Adenomatous polyposis coli protein repeat [IPR009223]", "Adenomatous polyposis coli protein, 15 residue repeat [IPR009240]", "Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Furin-like repeat [IPR006212]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "MORN motif [IPR003409]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome 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4.8945646029346714e-08 1.220543312426503e-06 5.244288534198133e-06 3.885892616591766e-09 4.0239026049171793e-08 +Protein targeting 49 120 4.611535027774581 3.9970628569196975e-06 30.48543689320388 111.54126213592232 1.595466660966077 0.3336055854889273 10.683999539888966 11.70327920021055 1.673091584234216 0.3988264387816677 2.140844309242146e-07 0.0012073658800308 0.0001555388564876 1.6103330413369685e-07 4.323719381879347e-09 +Establishment of protein localization 176 566 4.422173567719447 9.77129101387142e-06 118.26941747572816 516.7257281553398 0.6520395559374618 0.679532677582667 31.472560658738065 53.21298128179791 1.2523101724416292 0.4083128036600569 5.562977431501037e-06 0.01315167772046 0.0036450030953464 2.2606359978823463e-05 6.579214183815677e-11 +Mitochondrial transmembrane transport 34 53 4.30787325907759 1.6483178468584825e-05 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 5.145205919524012e-09 2.947739650573756e-06 1.5443406323716429e-06 1.0800871238854392e-07 2.7694389412322284e-09 +Endomembrane system organization 70 182 4.294739065974168 1.7489892261357554e-05 47.08980582524272 169.73058252427185 0.8987911429216844 0.5600148744834964 15.914797198368843 20.49740065572335 1.4161383035869868 0.4170367608227654 0.0041414100485099 0.1143079274466006 0.0042492830987498 0.0026050320333905 1.094997650151705e-07 +Membrane lipid metabolic process 20 42 4.282638799175776 1.8468985064856724e-05 15.813106796116504 37.71116504854369 1.423850539998867 0.1808469841706369 6.252884620395072 4.742042041181393 2.289538519382486 0.2724480316274368 1.4050529879928866e-07 0.0197758267942588 0.0010779549165811 1.076979596109781e-06 2.750566378038634e-07 +Sphingolipid metabolic process 16 33 4.126743957549516 3.679356560715164e-05 12.631067961165048 29.174757281553397 1.3566630100256978 0.1614907042591146 4.986857078326301 3.461093559903884 2.232073980338918 0.2503191978902473 9.759149580747997e-07 0.0102936075696032 0.0002941410216948 1.5216723372235428e-05 2.358117139783515e-06 +Protein localization to mitochondrion 30 61 4.108404934279019 3.98401132730708e-05 18.37621359223301 58.6747572815534 1.743973973786015 0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 1.752345584551342e-07 0.001748605497394 0.0039499040991049 2.908238193584641e-07 8.026079062941503e-09 +Establishment of protein localization to membrane 35 102 4.078775325230461 4.527356348416056e-05 23.133495145631063 87.3616504854369 1.231448880072231 0.4195243824117992 8.397245527204214 9.510228790351464 1.3947369206386535 0.4065372973031916 5.742158287172492e-05 0.07440901727418 0.0482692425760873 0.0004188057435368 1.7486441465496464e-07 +Cation transport 63 165 4.077909772799655 4.544239366999214e-05 40.9247572815534 152.4733009708738 1.0106305648473772 0.4693050539746304 15.98502541638414 15.374508146736815 1.5607432077940149 0.4143686874753333 0.0333148040433015 0.0091015487948617 0.1094648642009153 0.0171907708692124 0.0273884399993831 +Organic anion transport 28 49 3.951860637815288 7.754589848718574e-05 18.575242718446603 46.57281553398058 1.6158560948583975 0.2692356013040078 9.46386426798458 5.9518324529926545 1.7470285445738305 0.3371920110610632 0.0048786514783826 0.1520007577137938 0.0513626688490587 0.0025274832620095 0.0006111029710075 +Ion homeostasis 45 108 3.929463374978959 8.513564206924507e-05 28.021844660194176 105.69174757281552 0.8349951537384392 0.4299135801564597 10.40966729997928 11.411952082971936 1.4722934854811005 0.3963893325418664 0.0511347394786801 0.2134389652995229 0.0424184398029792 0.0303325381614789 0.0031752105289278 +Cation transmembrane transport 51 126 3.87847920067863 0.0001051115116057 33.43446601941748 118.4004854368932 1.1701058025505957 0.4085228823574113 14.425169362008605 12.553856783980793 1.6663185381795875 0.4066910074955585 0.0223193981400648 0.0086344442231225 0.1556688137304971 0.019017595089749 0.0257896067093858 +Cellular ion homeostasis 40 90 3.857778470109688 0.0001144222821842 24.48543689320388 87.34708737864078 0.921352068115914 0.4223079442129951 9.212290310790763 8.933596252465952 1.5207794649628892 0.4002972861975121 0.0429050176256222 0.379151373575087 0.04953941476756 0.0329420708219812 0.0017341543529716 +Anion transmembrane transport 26 44 3.8576397087049448 0.0001144872414358 18.02912621359223 42.29854368932039 1.9137296804814252 0.1915609440243116 8.771596162415214 5.032004157423188 1.8922368499585025 0.2935375719655638 0.0001652708094328 0.0019982551464922 0.0046116462239443 7.895712998334185e-05 2.6715701254780905e-05 +Intracellular protein transport 102 342 3.808593491348185 0.0001397595037542 72.23543689320388 320.84466019417476 0.4871189760263694 0.7214714639205947 20.45645165050656 29.914524602040487 1.0524664106682724 0.3751399671828122 1.537423300098709e-07 0.0156037217314595 0.0008741590567729 1.1047847577071548e-06 6.514157294493488e-10 +Intracellular transport 180 588 3.774741612576056 0.0001601735990195 120.90291262135922 544.3956310679612 0.5500812282996078 0.6924011803517542 31.43517433849213 53.582766758854405 1.193070641867047 0.396756529943003 1.7238037771498312e-06 0.0017998172207072 4.954003575480548e-06 6.258017231931237e-06 4.338946008842075e-09 +Protein targeting to mitochondrion 24 46 3.72900994135255 0.0001922335689479 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 4.254802011075416e-07 0.0008162643340865 0.0016161749700128 1.6459994208198165e-07 1.7391498666161893e-07 +Localization within membrane 60 209 3.712283972967752 0.0002053973505782 43.83252427184466 179.48543689320388 0.7329824809593914 0.5973922945503244 12.803162929787796 21.32668417309247 1.133148805830878 0.4087008058998355 0.0009137266317401 0.2001597763973769 0.0183284857370795 0.0005990596188359 6.407170513399914e-07 +Inorganic ion transmembrane transport 47 120 3.688688148122596 0.0002254133037309 32.300970873786405 111.99514563106796 0.9881513097876132 0.4268253140664947 13.185263141323642 11.586314982845243 1.7161030277526947 0.4113555760685328 0.0633591967073869 0.0056467720928151 0.0484266661807041 0.0375572726735054 0.0451658335361028 +Endoplasmic reticulum organization 23 46 3.65122382149875 0.0002609936595645 14.91747572815534 43.67718446601942 1.1418424810127707 0.3725584991544436 6.208589840117394 4.768440325801463 1.6823827875834556 0.3705219831566139 0.0001046400495416 0.3075216202298709 0.0062902743773976 0.0004690883853953 1.4718503239280654e-05 +Ceramide metabolic process 11 23 3.646450041429236 0.0002658881423138 8.191747572815533 19.060679611650485 1.0632949889077032 0.1865092544415649 3.2982239784478966 2.5917545738626013 1.8901201919357584 0.2494992632187684 1.0328781957842463e-06 0.0305319028295214 0.0022276957658844 7.83778432534745e-06 1.4660781943737655e-05 +Lytic vacuole organization 10 23 3.6266346955701296 0.0002871390666392 8.677184466019417 23.79368932038835 1.067589638534915 0.1668002350701783 2.8744208086829883 3.077266940940983 2.0111064761459874 0.2496786569477077 1.2777482294469352e-05 0.0335548880884004 1.6656079796260948e-06 1.2092573128436562e-05 0.0001266725713312 +Chemical homeostasis 62 188 3.6163100156099968 0.0002988324582968 43.762135922330096 177.7597087378641 0.7082111793088889 0.511106347874914 13.668464281922288 17.87763227716401 1.3204137511810292 0.4179418895476048 0.0002301617531556 0.1283171756643038 0.0027915131548814 0.0020533031835853 3.745186565245648e-05 +Membrane lipid biosynthetic process 10 26 3.531417420306977 0.0004133389026468 8.866504854368932 23.050970873786408 1.3229385051208649 0.2431293012321725 4.229937732502716 3.4850337476777224 1.635527795490498 0.2996124846932806 0.0001992505254972 0.0589240460435226 0.0082058667706489 0.0007832918499315 0.0019737688005078 +Carboxylic acid transport 20 38 3.462094264190057 0.0005359893923091 12.351941747572816 33.69417475728155 1.517249458545343 0.2522623764771551 6.23371050940395 4.11174791553619 1.419876490432768 0.3135855212793009 0.0050083794869595 0.0904452781629929 0.0189557671296911 0.0038170983466483 0.0016885745861375 +Protein transmembrane transport 14 28 3.449621810652556 0.0005613724000212 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 2.9836859497131724e-05 0.0020640692536444 1.1421997294757266e-05 3.5525803469399624e-05 1.8497204421901472e-08 +Oxidative phosphorylation 31 65 3.446898512124944 0.0005670615568984 18.140776699029125 60.61893203883495 0.8137621380364766 0.3661293054253088 7.750013302753429 5.582386553809936 1.7413544544034578 0.3762713520958283 7.260100110651884e-05 0.0002518558292813 0.0010320425846939 2.872931465890857e-05 1.6335433939661455e-05 +Golgi vesicle transport 37 142 3.423295197633876 0.0006186685171418 32.30825242718446 130.0995145631068 0.5186556770214802 0.6391424830765352 11.558195085956042 14.851278907933963 1.0581936514451007 0.3745819971007444 0.0631026818636529 0.037035881913773 0.0139415974534106 0.0256837879501232 1.1498838774692085e-05 +Endoplasmic reticulum to golgi vesicle mediated transport 20 67 3.4002894987265235 0.0006731454306121 17.32766990291262 65.39077669902913 0.808881464821498 0.4942452999677598 7.539018980743236 6.620812461410292 1.284359804176963 0.3933269611423161 0.0643953868715604 0.0176779282664691 0.0051572349075885 0.0595274334568858 1.006307438411793e-05 +Lipid localization 25 87 3.397198751560751 0.0006807950062561 20.1504854368932 74.27912621359224 1.3966421040883936 0.3001252105784707 7.306180038477171 9.39465098860316 1.572418240819249 0.3627304234720817 0.0013226138672853 0.0212658195237354 9.145266356827453e-06 0.0009263382354536 2.5785354424225223e-05 +Sphingolipid biosynthetic process 8 19 3.3851623456531588 0.0007113616834368 6.543689320388349 16.33252427184466 1.3108583596388097 0.2293036031089034 3.2058099533310203 2.4273143169149307 1.5209865792019848 0.2861850290041513 0.0004177740672846 0.0325345581006573 0.0025290933815156 0.0028705350867404 0.0020304614421714 +Vesicle mediated transport 87 390 3.380113038799956 0.0007245602353214 80.64805825242719 354.7718446601942 0.3002670711784583 0.7468304035232791 23.646053491950397 43.46537941024834 1.061791523718338 0.3560152131667141 0.1117981210872605 0.1068761998369296 0.0168063488536953 0.1347782994796449 0.0005223622536397 +Organic acid transmembrane transport 22 36 3.379000090841408 0.0007274998411197 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 0.01143955037029 0.0564048148733258 0.1821593613874541 0.0126135475433129 0.000451259348622 +Liposaccharide metabolic process 14 21 3.37880945916952 0.0007280044624715 7.393203883495145 16.839805825242717 0.7162233803449398 0.1804705798886219 2.8837934205508033 2.921890590438037 1.8930166841377585 0.2403675114219934 0.0003708806936625 0.2443632781182481 0.1088269092294783 0.0004601600061541 0.0004297622117065 +Glycoprotein metabolic process 32 70 3.3780345690505693 0.0007300590240728 18.59223300970874 59.577669902912625 0.8707431654759812 0.409720724299967 7.543964208858723 9.989377193127202 1.488085349392555 0.3835029669336279 0.0900133835561178 1.0 0.6487438131622403 0.180231405183943 0.0141684349736485 +Mitochondrial membrane organization 26 48 3.3723568834722712 0.0007452780822549 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 3.627538360745964e-05 0.0775893010402436 0.0664874170634557 0.0004992077555357 1.3742757644399154e-07 +Mitochondrial respiratory chain complex assembly 25 44 3.3470504782178745 0.0008167633612321 14.427184466019416 38.300970873786405 1.6683402305651691 0.229838901803248 5.648441561419256 5.588363345618 1.6629328950455762 0.3088219725228932 0.0001043062772589 0.0094231818265578 0.0117389654214918 6.439621012544542e-05 2.9365621493531424e-05 +Glycoprotein biosynthetic process 26 61 3.3328485916123216 0.0008596170889234 16.72087378640777 51.87378640776699 1.042113998842759 0.381483262234126 6.756316800759528 8.908847583990125 1.5232206853916193 0.3819786061588057 0.0329947574883968 1.0 0.5538761389611022 0.0891710179820889 0.0051580809413311 +Monovalent inorganic cation homeostasis 16 29 3.316700388102197 0.0009108724010511 9.014563106796116 27.87378640776699 1.1567920478867002 0.2845186374336156 4.051822262152646 3.607380814764068 1.4117439861533438 0.3149022278800241 0.0070347645687546 0.297366720714231 0.0006947605035307 0.0018365459096632 0.0007433462591317 +Metal ion homeostasis 33 81 3.3158086293115496 0.0009137837970105 22.37864077669903 79.5 0.7762327689006491 0.4501210966631583 8.485414676383348 8.298876985671072 1.3957415688189287 0.3857448193070677 0.1884643101272404 0.3617750709606537 0.2521638838884718 0.1855351247373664 0.0548790014851445 +Cellular monovalent inorganic cation homeostasis 15 27 3.2962256931371683 0.0009799325760015 8.191747572815533 25.12378640776699 1.1978511848260835 0.2636491484517694 3.558748260132903 2.9783551257949803 1.4212259473978417 0.3021468238591936 0.0025749109983972 0.2552681350600493 0.0003016125361838 0.0006279861154086 0.0006517545393382 +Organic acid transport 26 52 3.295630304222277 0.0009820115051679 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.025600450838487 0.1403881914917208 0.044160808858811 0.0178098913666631 0.0009851538934748 +Intracellular protein transmembrane transport 11 24 3.2753696753042725 0.0010552378962973 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 5.902665819989003e-05 0.0196403757049561 7.001976104570308e-05 9.063996119237736e-05 1.016607930036332e-06 +Regulation of ph 12 22 3.2696594137592574 0.0010767704566156 6.890776699029126 20.859223300970875 1.2151699598837196 0.2373503364294603 2.930458126920059 2.7746402510870145 1.4154672965603718 0.2873526492076106 0.0009994719800065 0.2220822570468345 0.0001411644236219 0.0002314913891327 0.0001692953162957 +Regulation of cellular ph 12 22 3.2696594137592574 0.0010767704566156 6.885922330097087 20.844660194174757 1.215766922704761 0.2375185297794358 2.9319293283093293 2.765976649626597 1.4143296516981956 0.2875299337708636 0.0006943470784876 0.2107016729382093 0.0001059830796752 0.0001580597168237 0.0001002672586078 +Vacuole organization 21 52 3.202559767113099 0.0013621203205791 14.220873786407768 51.74514563106796 0.8524122478550634 0.3147425083910056 5.370022076358251 7.439112114793103 1.7567175511320523 0.3563110134355993 0.0083840239420472 0.1706177828799348 0.0007575328824125 0.0127416531618932 0.0388401839530869 +Protein insertion into membrane 15 31 3.175834903027968 0.0014940595418269 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 2.162207829666599e-05 0.0248381956323572 0.0132042256106822 2.660702259682677e-05 4.296304877024734e-06 +Lipoprotein metabolic process 6 18 3.149991888815011 0.00163274995573 5.504854368932039 19.114077669902912 1.0723975558987071 0.2794846862458811 2.648039342123219 3.7213756556771336 1.2556798055308762 0.2951644225033464 0.0156202968480086 0.0627750690965546 0.0092927708056161 0.0043610876134259 0.1191020144375228 +Inner mitochondrial membrane organization 13 22 3.1184488046099195 0.0018180572397306 9.985436893203884 20.800970873786408 1.138268089020681 0.2873707765098114 4.6289277788641146 2.4012939531921327 1.609232985153232 0.3229583948801056 1.3101360370528447e-05 1.0 0.3034780999558708 0.001820540651884 9.354980213840477e-08 +Cellular macromolecule localization 169 597 3.103350151310174 0.0019134310604078 116.74029126213593 544.3228155339806 0.3819130491508938 0.7577794226812853 28.882302639166586 53.383983306101904 0.8794377571334007 0.3523979567946485 8.348019616481864e-06 0.0193598289295067 0.0068217955520587 4.748095855063809e-05 5.0120077578006644e-08 +Secondary alcohol metabolic process 16 43 3.08949519822335 0.002004969474914 12.097087378640778 42.24514563106796 1.5200936296432006 0.2566232504859334 4.463475425703621 3.883072640851752 1.3223501002339118 0.3210874999447533 1.3194864913017618e-05 0.343540942585206 0.0015360029240361 0.0002383090606227 7.601481383823173e-07 +Regulation of lysosomal lumen ph 3 5 3.070762205770527 0.002135131221397 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 0.0009203602780865 0.0697581245313758 0.0003712110430798 0.000366006536683 0.0049176108076387 +Membrane lipid catabolic process 8 13 3.0398191729337785 0.0023672022926843 5.854368932038835 11.361650485436892 0.500872843713425 0.1363587272813367 1.9603237645724247 0.9867004907377388 2.113024793917032 0.2289617793743788 6.754533897202459e-08 0.0040679264544396 3.5959740301631905e-05 2.591400071592553e-07 1.4750631476459234e-07 +Macroautophagy 39 107 3.012765561335489 0.0025887882245545 25.570388349514563 102.68203883495146 0.4734815024857951 0.6429834425349866 8.949285204664525 14.162660044372751 0.8554944786686205 0.3590213706304501 0.1948526414498231 0.3652641381602879 0.11517267631025 0.4582075020987074 0.0188897906876298 +Steroid metabolic process 23 70 3.011001267586586 0.0026038776559331 17.82766990291262 66.9247572815534 0.9974586731388552 0.3270410156332073 6.090491666967852 5.93996409793671 1.7133199907504504 0.3720334828404655 0.00031994102035 0.1723298875515411 0.0007869081300806 0.0003875037004476 6.601519206221846e-05 +Inorganic anion transport 17 27 2.967960251415298 0.0029978309491802 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 0.0012074013384908 0.0003235415753736 0.0005359635089116 0.0002404412649958 4.530035964786033e-06 +Regulation of mitochondrion organization 22 48 2.9488726530507785 0.0031893536754972 12.08980582524272 45.08252427184466 0.8217268052205459 0.4563186211764868 4.409741308614158 5.146210353910189 1.120993905462196 0.3778427085178187 0.0021910685592402 0.4158765777114258 0.2930966068708724 0.0517677960003906 2.3705212738622743e-05 +Golgi organization 23 59 2.947853164780572 0.0031998901515164 16.643203883495147 56.43689320388349 0.631232933893225 0.5683910993217528 6.594450257690171 8.413373430660274 1.0599635722797485 0.3790700076783576 0.1833333624460683 0.4517357114503159 0.0324050574998744 0.0793927108250854 0.0027525230314119 +Protein exit from endoplasmic reticulum 12 24 2.9205551752583743 0.0034940831990457 7.002427184466019 21.233009708737864 0.6943602976218084 0.4745028866201709 3.210645812910548 2.182026685495945 1.0430444956616387 0.3507892727806736 0.0099021023973698 0.187449079081247 0.0651781855152293 0.0846608217542885 0.0001817739981452 +Regulation of autophagy 28 99 2.9057081139514325 0.0036642308592649 20.118932038834952 94.3495145631068 0.711099590941891 0.531831837860264 6.9602150135047 11.998348379757145 0.9791686068293384 0.3767967479294735 0.0418190530557766 0.3774217541644473 0.0164950478197308 0.0653267372514331 0.0133035661496812 +Process utilizing autophagic mechanism 58 168 2.900097145543228 0.0037304702396727 37.22330097087379 158.8252427184466 0.4533218180510577 0.6759877406594806 11.85403297791327 20.589929287102564 0.8897283418769861 0.36588075882003 0.1989155806681013 0.6310562795845085 0.1353697247026293 0.4960951191430938 0.0049680311723839 +Ceramide biosynthetic process 5 13 2.8751455866444005 0.0040384124079932 4.033980582524272 10.24757281553398 1.048715387316577 0.2344614502118888 2.237979905601341 2.0281678881596505 1.4071730245015133 0.2685344998940062 0.000620667938722 0.0121686135974036 0.0046396659223567 0.0014099836558107 0.0062617463102783 +Sterol metabolic process 14 38 2.869338394445866 0.0041133146835055 11.932038834951456 38.44660194174757 1.1656335789111734 0.2523239777622673 4.346099994655023 4.0619669904912925 1.6676089351046874 0.3062687621764124 0.000268662984322 0.3371313972628795 0.0013844952123512 0.0009941384248502 1.2606619012664512e-05 +Amino acid transport 15 21 2.8428995322687296 0.0044705160187463 7.771844660194175 19.75 0.8410032854505353 0.3449280742441291 4.117377746800764 3.003739578643708 1.287399790463736 0.3206698223659758 0.0610073025771906 1.0 0.4911024875738272 0.0252514374511772 0.0496567653265115 +Porphyrin containing compound metabolic process 4 18 2.840592094172408 0.0045029868998733 4.91747572815534 16.531553398058254 1.0269348271542438 0.279733852070357 2.276512713100022 2.089380108414912 1.2578863722796805 0.2914421038569487 0.0040775097697983 2.2092196106924005e-05 0.0003475618019176 0.0014099836558107 0.0062617463102783 +Protein transmembrane import into intracellular organelle 7 15 2.8373231458617045 0.0045493542338044 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.000258438940371 0.0090330503435184 0.0001888015632795 0.0006827439557333 6.711779371444596e-05 +Divalent inorganic cation homeostasis 23 56 2.8081306768982217 0.0049830002077886 15.361650485436892 54.019417475728154 0.5485088157809707 0.5170537035394376 6.04857242197355 6.215359275440269 1.1779017300469032 0.3778837346959196 0.3339015767261843 1.0 1.0 0.4533933095675377 0.1097939825183114 +Protein localization to endoplasmic reticulum 13 38 2.8041669834388685 0.0050446770838401 9.50242718446602 34.50485436893204 0.9935384348474128 0.428255638055916 4.399083524593319 2.6617527855555916 1.1934894982037212 0.3717243536861919 0.0003283635502972 0.0305319028295214 0.0022276957658844 0.0004129808075874 2.4967989534272657e-06 +Proton transmembrane transport 19 43 2.802822108554775 0.0050657602433501 14.28640776699029 43.01699029126213 0.7821394801431882 0.3918912894345224 6.076814900000799 3.1076483585332 1.5710697941383835 0.3739424994204808 0.0256965218853548 0.0010451763347091 0.0131034302652722 0.0075397092471439 0.0388539220133518 +Response to oxygen levels 20 66 2.7994526361151952 0.0051189325687472 12.5 62.737864077669904 0.8042614609462893 0.4659445696529398 5.042296826006319 7.106965221607376 0.959407798819026 0.3671515409983293 0.1417002249657338 0.0135804389838838 0.0005607350640202 0.0442169217875986 0.0877904059359194 +Regulation of blood pressure 9 18 2.7920476378729195 0.0052375644537958 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.0019194312531417 0.0315268496209905 0.1088269092294783 0.0127222619547071 0.0017963005545976 +Carbohydrate derivative transport 12 16 2.765652300927353 0.0056809070548835 7.924757281553398 17.024271844660195 1.3665639952580566 0.1869571280171947 4.210097511648942 2.624454303682939 1.5541767319140831 0.2467993156006303 0.0130879818364426 1.0 0.0733374275738533 0.0244406528674846 0.0015084049643282 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 9 30 2.7368367952660826 0.0062033059895052 7.771844660194175 26.825242718446603 1.1714448828781496 0.3436005361805324 3.811248488859092 3.450558374586287 1.1733172803389544 0.345676809182098 0.0558973394214976 0.0014578554854327 0.0010831329822185 0.0262238710799836 0.0003693854345286 +Sphingoid metabolic process 2 5 2.7214117134188545 0.0065003746014249 2.337378640776699 5.174757281553398 0.8258730035764346 0.2192038420096116 1.196784089801513 0.5941001920342514 1.4738240163378542 0.2563928956394505 0.0029552410756802 0.0470522829573702 0.0039921150854813 0.0229613270793894 0.0106255777102749 +Metal ion transport 42 109 2.718500250126431 0.0065578606174783 24.868932038834952 99.21116504854368 0.6600358663497399 0.5322554902435589 9.162889792248723 11.473971032908404 1.1670714049066973 0.3920241658733104 0.3857925807907909 0.5023005139274972 0.6621409761645409 0.4641514487312835 0.2506564946032383 +Macromolecule depalmitoylation 3 5 2.7114987002437374 0.0066979803656612 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0003591188143491 0.0561990347849709 0.0057815105752346 0.0001405335592956 0.0020033682110678 +Tetrapyrrole metabolic process 4 21 2.70887025305328 0.0067512735822234 5.652912621359223 19.283980582524272 1.0342508202848784 0.290677507336007 2.6828141040028877 2.549402305664568 1.2308389507353266 0.2976223887279709 0.0108972369658975 5.54862191388683e-05 0.0008428863370275 0.0039562767661884 0.018870184963526 +Organelle fusion 21 48 2.684281622551144 0.0072685850646976 14.74514563106796 45.383495145631066 0.6448767361523368 0.5292766623385164 6.293825046556003 6.576179389035289 1.1045479661060835 0.3741954647136961 0.0668182318570721 1.0 0.6796339643303746 0.3069279042634235 0.001459560308497 +Cytochrome complex assembly 6 14 2.67589152569237 0.0074530763269984 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 0.0035836752225035 0.0115082778780227 0.0428134756181982 0.0012324742743759 0.0010565154778331 +Cellular homeostasis 56 150 2.6677332231725277 0.0076364867500839 35.03155339805825 140.69660194174756 0.4666088113804902 0.5685618966047314 11.62423291193178 14.777892439656425 1.1736922314243927 0.3887657095146841 0.2321620655746276 0.6092881231437158 0.2280094036947441 0.2222979326087123 0.02415991177029 +Signal peptide processing 2 5 2.655973908026416 0.0079079732709332 2.0898058252427183 5.155339805825243 0.788498872885968 0.2357910477072221 1.2938213743418876 0.7208043181852656 1.3841109341751536 0.2490116896927748 0.0039714533726283 1.0 0.0001384716540127 0.001983278822638 0.0140894483762481 +Vacuolar acidification 4 8 2.652716467967675 0.0079846910928029 3.4757281553398056 8.922330097087379 1.27407749822917 0.1611429668415415 1.4148632661931722 1.303016071016461 1.4195929612668792 0.2212670077717619 0.0001651994968582 0.083126337411673 6.043050183903694e-07 5.200397996359343e-05 0.0013491401517078 +Endocytosis 28 131 2.65150896370154 0.0080132985951635 25.6626213592233 116.14077669902912 0.4088637809343856 0.6347066552957155 9.675324480764845 15.608206311139906 1.1645342915127963 0.3689266363473043 0.0407549747306873 0.2337436819955417 0.2492815819080167 0.1362001381441055 0.0193910669844568 +Organophosphate ester transport 8 30 2.6355837284679 0.0083992700962849 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 0.0346017309347893 0.0551599902794207 0.0413282647695778 0.0418340682466743 0.014156638351275 +Respiratory electron transport chain 28 54 2.6329905581550355 0.0084636700168716 15.4126213592233 50.33495145631068 0.497076868891423 0.4388579749555677 7.129498131980449 4.223655269147207 1.4894225458303931 0.3736358875877055 0.0093865734043821 0.0108990791164893 0.0023726768380501 0.0084325378638661 0.0023152575232889 +Glycosylation 19 50 2.630850174978872 0.008517157492015 13.33495145631068 45.42718446601942 0.831363055351092 0.4028474919440285 5.5712021107485015 7.578523489860055 1.3433056638769032 0.3649215649501745 0.0627909456600843 1.0 0.2082314162172194 0.1973207141258839 0.0964139397996599 +Establishment of protein localization to organelle 44 193 2.624053609507456 0.0086890107519395 40.4247572815534 180.123786407767 0.6176411706537287 0.628535284461401 14.116769229706104 14.40373863390995 1.0281809729691214 0.3983757503188239 0.0034041870122034 0.027661626952048 0.0077455897465029 0.0010309564670862 1.037081988056191e-05 +Carbohydrate derivative catabolic process 14 34 2.6228594616059797 0.008719523209864 9.92233009708738 34.20388349514563 -0.0123085756499559 0.2707665028006943 3.843893961107642 3.291233496452993 1.7787241070250257 0.2878972939517332 0.0001956280236887 0.4243503559946278 0.0247838106247756 9.279779242045584e-05 0.0003988797412372 +Aminoglycan catabolic process 4 5 2.6171561134419625 0.0088665779458134 2.6893203883495147 4.728155339805825 0.5164809724591738 0.1764823388548578 1.1619294817897845 0.7656988020633148 1.69808407883546 0.2279588459746903 0.005175564892058 1.0 0.1105474823156849 0.0025975272437437 0.0001590313802548 +Glycosaminoglycan catabolic process 4 5 2.6171561134419625 0.0088665779458134 2.6432038834951457 4.665048543689321 0.5167433573606753 0.1777854895826483 1.1305026922003756 0.6751064263980151 1.6910244329591049 0.2288538535307848 0.0039714533726283 1.0 0.1018169846714528 0.001983278822638 9.662113775844424e-05 +Aminoglycan metabolic process 9 15 2.611137261364528 0.009024166545331 6.650485436893204 15.218446601941748 0.5538240398360251 0.1973407167351751 2.4739761552565955 2.4752855115427597 1.8355272359461776 0.2521795038965069 0.0028277793470322 1.0 0.1215022402141297 0.0036888619541724 0.0007440053524939 +Regulation of cysteine type endopeptidase activity 19 52 2.607683571121266 0.009115717779178 11.024271844660197 48.30339805825243 0.4412193551169824 0.5489802671194735 4.186129802361243 4.9529522535570285 0.919025397001871 0.3400648922313719 0.0719594577794459 1.0 0.4023614946307436 0.0215982709727899 0.0037693987860826 +Glycolipid biosynthetic process 6 11 2.597090012519605 0.0094017282861822 3.3009708737864076 8.701456310679612 0.8778541677747596 0.2891249509557468 2.0940737065519093 2.1465026455410077 1.206628042966233 0.2848826766737565 0.0981383338461147 0.1594721229818057 0.2966243410810411 0.0552623668853733 0.0957448321565225 +Amino acid transmembrane transport 12 16 2.579917327143893 0.0098823970562447 6.213592233009709 14.228155339805824 0.7890307267204019 0.3318923540291705 3.493823914060917 1.9561661273054285 1.3497309258640615 0.3227865040448734 0.0558973394214976 1.0 1.0 0.0262238710799836 0.0767262889545654 +Ph reduction 8 12 2.5775049509261327 0.0099516455899713 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 0.001471682867815 0.1263420182810564 6.418208082332269e-06 0.0004897389809093 0.0002995500484788 +Anterior posterior axis specification 4 7 2.5656391875429767 0.0102985893277289 2.150485436893204 7.883495145631068 0.2367617882356813 0.4134048913234588 1.4769013604261771 1.846281862553996 1.0893705082441092 0.2769448547029782 0.001471682867815 1.0 0.239336332644921 0.0291459656321865 0.0103633783340074 +Positive regulation of b cell activation 2 12 2.5652109580833176 0.0103113091929307 3.092233009708738 11.186893203883496 0.1859276114166038 0.5045227221699764 1.8118375224733587 1.264344128777142 1.0073127631140006 0.3002532228225043 0.1244418575004597 0.1755724648168266 0.0067632743899401 0.0713646261968556 0.3081896593873433 +Positive regulation of necrotic cell death 1 5 2.5599203943328543 0.0104696142330453 1.577669902912621 5.262135922330097 0.5638344924795549 0.4335998879538771 1.168471912149588 0.9650309623137224 1.027471527178098 0.3152978961085739 0.0361319669005298 0.0470522829573702 0.0930016660897952 0.0229613270793894 0.0820486275159116 +Cellular respiration 42 109 2.546245387311843 0.0108888614074826 27.975728155339805 102.1019417475728 0.3887198796668061 0.4496840882999475 12.70690482749566 7.191843824002275 1.6294784865611704 0.3894421445164553 7.253345056253013e-05 0.002043613805171 0.0023833705705514 5.152363528169574e-05 4.409469146971408e-05 +Negative regulation of blood pressure 2 5 2.545300181733964 0.0109183832898267 1.3883495145631068 4.186893203883495 0.7622294394612346 0.2478679651965233 0.7661910546387906 0.5883356962714492 1.358951451673839 0.2503899088710304 0.0361319669005298 0.0470522829573702 0.0930016660897952 0.0229613270793894 0.0106255777102749 +Glycosphingolipid metabolic process 9 13 2.5450435256093087 0.0109264117755487 4.764563106796117 9.184466019417476 0.4485135251287195 0.1553285492394019 1.7516723087054535 1.7320372023153958 1.93068386398988 0.2217231968869004 0.003134273726162 0.1471951297158956 0.0405463165390607 0.0078094686864188 0.0008750939624126 +Lipid metabolic process 104 297 2.5399152775735514 0.0110879324658099 70.49514563106796 273.7014563106796 0.4234492243219149 0.5257500979287635 24.98470358696109 28.74867152381156 1.6795947056521872 0.4126649977131845 7.98437203276743e-08 0.0783240828040884 5.04786660886654e-05 6.279505651196278e-07 4.778278744296947e-10 +Aerobic respiration 29 92 2.5242196620375275 0.0115955448043876 23.075242718446603 86.43446601941747 0.4685851027775424 0.4381258038241513 10.546552774557412 6.275478278783705 1.570513830163352 0.3792860784147517 3.040165955039593e-05 0.0009492885248983 0.0044497862190796 2.9295115710827377e-05 2.7817272155686708e-05 +Blastoderm segmentation 2 5 2.514924424213285 0.0119057902508623 1.2451456310679612 3.9635922330097086 0.3458052520338603 0.4644407421564997 0.970737247680499 0.963476063526343 1.006276792431962 0.2955521606034098 0.009996551282915 1.0 1.0 0.3069124011154697 0.0336357980244025 +Lipoprotein catabolic process 2 5 2.511081195278729 0.0120362009269816 1.529126213592233 5.211165048543689 0.7074087979902727 0.279320898549559 1.1111204061152251 0.9407555329409328 1.2623530327786678 0.2599848817817885 0.009996551282915 0.0697581245313758 0.1362380906066266 0.0050923434600555 0.0336357980244025 +Transition metal ion transport 5 13 2.5060199320320384 0.0122098736656555 4.70873786407767 14.08980582524272 0.8861898222657586 0.2678437025860737 2.4756329698054333 2.718007722894407 1.3738160036140448 0.271065502827487 0.1078454276129304 0.2480154974279715 0.4386006499544391 0.1700362094205073 0.1582577568656886 +Response to oxidative stress 33 100 2.50544778722436 0.0122296453286621 18.145631067961165 95.9757281553398 0.5057872201816154 0.5358657948719677 6.785060354870026 9.30128883458378 0.9511882590088212 0.3606217523881886 0.119300758182676 0.1659675721465734 0.1557674764743414 0.1711686143031237 0.0086197401734343 +Lysosomal protein catabolic process 2 9 2.4985844930873293 0.0124690414015093 2.6941747572815533 6.587378640776699 0.838918419522322 0.2080383809566978 1.5899151374262637 1.8707342212441815 1.5239608036504366 0.2420459791980847 0.01674854618918 1.0 0.0006517968090871 0.0086586519898169 0.0541965943180989 +Protein catabolic process in the vacuole 2 9 2.4985844930873293 0.0124690414015093 2.70873786407767 6.618932038834951 0.8383076008345888 0.2101105309103242 1.6017652153393662 1.88837291272598 1.5176899437744062 0.242508547144668 0.0223651585611987 1.0 0.0008978593047678 0.0116756742779249 0.0705348016344186 +Neuron apoptotic process 18 51 2.49848694929932 0.0124724734923822 11.191747572815531 49.65533980582524 0.9007291731588002 0.4299023129629146 4.0102574614548505 4.518854312987721 0.9862249081516458 0.3541854094791909 0.0866587403967184 0.1587221484945262 0.014474163498145 0.0670546193669445 0.0281196880783471 +Selective autophagy 14 29 2.497996482547118 0.01248974331045 7.861650485436893 28.031553398058257 0.6116968756419903 0.5194450063363468 3.450451665126401 4.3159755745103565 0.9002253779314615 0.3454803983634653 0.0550370045311565 0.2766173679843171 0.4810063700036922 0.2193268794643932 0.0155196297710904 +Rna stabilization 9 26 2.4971879276798337 0.0125182595552619 9.359223300970871 27.37621359223301 0.4792302048577673 0.5262457931829767 4.411160534464403 1.6856669427134765 1.0994939820726763 0.3614208213771557 0.0169025742456574 1.0 0.3807425591652282 0.0063027604866002 0.0022946198906289 +Maintenance of protein localization in endoplasmic reticulum 3 5 2.4845534159598577 0.0129714046108277 1.203883495145631 3.203883495145631 1.1364527439994954 0.2609157960586762 1.0226486010276945 1.0226486010276945 1.138989616014889 0.2624735143617788 0.0014439053642014 0.0006219606051344 0.0025156479029566 0.0007102815399137 0.0003311660608568 +Protein retention in er lumen 3 5 2.4845534159598577 0.0129714046108277 1.203883495145631 3.203883495145631 1.1364527439994954 0.2609157960586762 1.0226486010276945 1.0226486010276945 1.138989616014889 0.2624735143617788 0.0005399847281173 0.0003352480301583 0.0013648737359616 0.0002629541815867 7.675515939222757e-05 +Atp synthesis coupled electron transport 20 41 2.48271632599702 0.013038487321433 11.567961165048544 37.61407766990291 0.6403585631460136 0.4181082416574377 5.189865284224125 3.9859091462453993 1.417482213086961 0.3703097362636519 0.010019183130841 0.006163378346249 0.006891590705249 0.0112163349420639 0.0013056967129913 +Alcohol metabolic process 24 81 2.472657258970367 0.0134112694304013 19.300970873786408 81.99029126213593 1.0392616248309592 0.3936245775900834 6.9548962308345 7.403089286448431 1.208378917036781 0.3759976884392474 0.0007302735143621 0.2658534516448619 0.0159805457687977 0.0047266194080703 2.7773737403370672e-05 +Endoplasmic reticulum membrane organization 6 8 2.4725636350243803 0.0134147828634003 3.5679611650485437 8.12621359223301 0.656874598832497 0.271683145803182 1.813579499342004 1.2879547393790816 1.532817064292788 0.2945772195616556 0.000506203921404 1.0 0.0067896670197663 0.0001991597833083 0.0002481332774246 +Establishment of protein localization to mitochondrial membrane 9 19 2.4541794253846785 0.0141206505260436 5.572815533980583 16.524271844660195 1.1986544459127668 0.291784793504827 2.8501471321161915 2.5441524813639957 1.2232399066733852 0.3232066755573589 0.0012397233896807 0.1221118561195742 0.2318581098993339 0.0004102788019959 0.000234374088003 +Mitochondrial electron transport ubiquinol to cytochrome c 1 5 2.453591072554257 0.0141437719384436 1.5048543689320388 4.206310679611651 0.8658650693935839 0.2665349265497743 0.9514810775456936 0.7935779738409815 1.3072925004771625 0.2886561243868636 0.0294966217370324 0.0424464003246627 0.0032139762811053 0.0186627473263165 0.0677640175569944 +Positive regulation of t cell mediated cytotoxicity 3 5 2.449542607288319 0.0143037785641753 1.674757281553398 4.135922330097087 0.7411503285093088 0.380666699308082 1.1042915794952284 0.779575982450709 0.9911557427348976 0.2979075232652237 0.3548108655020613 1.0 1.0 1.0 0.0278921605814954 +Regulation of t cell mediated cytotoxicity 3 5 2.449542607288319 0.0143037785641753 1.674757281553398 4.135922330097087 0.7411503285093088 0.380666699308082 1.1042915794952284 0.779575982450709 0.9911557427348976 0.2979075232652237 0.3747076822525905 1.0 1.0 1.0 0.0336357980244025 +Neuron death 28 79 2.445430666736049 0.0144679263399125 14.20388349514563 73.25242718446601 0.8007457732231772 0.4829929240620625 5.370919943079612 7.537889337352574 0.9625497526284538 0.3667297831171348 0.0798141209212823 0.2873388595440179 0.0637353710047468 0.041648628319696 0.0055077405410857 +Membrane fusion 13 47 2.4402198931159056 0.0146783241777361 11.592233009708735 41.140776699029125 0.24764888033976 0.6429045305046197 5.404397514006145 5.499742922380336 0.8586283816511532 0.3399356769366213 0.2627419819199233 1.0 0.2966953076606857 0.1339560302608873 0.0201706348246818 +Respiratory chain complex iii assembly 2 7 2.433984189898695 0.0149336473556036 1.8470873786407769 5.160194174757281 1.360931378136811 0.1995688008303064 1.0650749835200868 1.2360161344522411 1.0120439004969468 0.2366879233397748 0.0014439053642014 0.0378187125466048 0.075113296023457 0.0007102815399137 0.0053334351931861 +L amino acid transport 11 13 2.4258255837274043 0.0152736087247644 5.114077669902913 11.91504854368932 0.7755289387861473 0.3283794523692901 2.998235059113201 1.3256494094845783 1.3058948249973923 0.3189923022900864 0.0197718902859207 1.0 1.0 0.0086864012748381 0.0231294135439989 +Organelle membrane fusion 11 33 2.422674018134313 0.0154067448015708 9.026699029126211 29.49271844660194 0.2503440438263548 0.5991935201964022 4.297974887399588 5.110663265938685 0.9179616425810708 0.3357137012753883 0.2661339780708401 1.0 0.565173788309953 0.1492356701793886 0.0219681008445407 +Pinocytosis 3 8 2.4218932856640096 0.0154398838490541 1.8713592233009708 7.33252427184466 0.5840579949486326 0.3745201042297812 1.4960968950914608 1.2320991783672317 1.0871891924456092 0.2933375341256155 0.1046893250830714 0.083126337411673 0.1611939416425752 0.0688460117016781 0.0541965943180989 +Cellular hormone metabolic process 9 19 2.414561805097152 0.015754149935363 5.441747572815534 17.32766990291262 0.9908884218524354 0.2940959275691314 2.8170777488519256 1.7185203072340225 1.2515909253444888 0.3031653223897966 0.0198174339809626 0.2183067054048652 0.0132042256106822 0.0074685925596388 0.0111707611872444 +Iron ion homeostasis 3 17 2.412213330030067 0.015856000987134 4.468446601941747 17.140776699029125 1.0306963602610326 0.26770320823289 2.1032740346004313 1.762496954108992 1.1437451534606062 0.2692749918411525 0.0713115326198003 0.0248381956323572 0.0014732567036546 0.0341229578056568 0.2352128770122224 +Regulation of protein folding 3 5 2.411162493555892 0.015901761948013 1.4684466019417477 3.9902912621359223 0.8007742626376635 0.414912404617451 0.9636472557717446 0.4350012974217447 0.8403398140210957 0.3064934164835685 0.0179201169927304 1.0 1.0 0.0112385866308786 0.003457584268524 +Embryonic pattern specification 3 8 2.411070396382934 0.0159057780494524 1.7888349514563109 6.800970873786408 0.2174397468660829 0.4216094133238752 1.3059132139133678 1.2825183922018937 1.0534562874337137 0.2678063530105666 0.0286114952840351 1.0 0.3102657432506607 0.2332121755087385 0.1114244714574529 +Positive regulation of peptidase activity 16 45 2.409897450643027 0.0159570050189008 10.402912621359222 41.05582524271845 0.5528457293594794 0.5353148532065843 3.6877903061155113 4.060739093918417 0.9383664509883394 0.3555881721715914 0.0797477089384006 1.0 0.3289373622252651 0.0724012208448934 0.0058713612820935 +Embryonic axis specification 3 6 2.408976023791914 0.0159973488910498 1.7087378640776698 6.189320388349515 0.1774603788996648 0.4011313163108394 1.3007172626301904 1.1117564709725614 1.0979971050109048 0.2636991278685997 0.0049168061240519 1.0 0.2012104780589677 0.1053546389470493 0.0234644839392777 +Protein import into mitochondrial matrix 6 9 2.4061888197648384 0.0161199306065107 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0009203602780865 0.0022827689145391 0.0090253131212995 0.0050923434600555 0.0005338561483377 +Negative regulation of mrna catabolic process 9 24 2.39792392484445 0.016488289277055 9.169902912621358 24.631067961165048 0.5652120707700043 0.4958815262040553 4.097153521759381 1.8459627491120816 1.1372403168685192 0.3560626632344691 0.0024065982626419 1.0 0.3559802976275766 0.0043649502990921 0.0013003096338674 +Positive regulation of mitochondrion organization 11 23 2.3935291324599097 0.0166871560725951 6.235436893203883 22.393203883495147 0.6669540243221574 0.4355223453199826 2.7589935116766484 2.962672702300372 1.01251720769805 0.3295170825531805 0.0055250040933259 0.225839943305071 0.0935352604171004 0.0087768454005906 0.0136894768366188 +Glycoside catabolic process 5 6 2.391105708801779 0.0167977157051748 2.995145631067961 5.604368932038835 0.914408298188202 0.1915126053981477 1.4021397407455505 0.554137429771367 1.5051386650706404 0.245673751384095 1.3928177152137746e-06 1.0 0.075113296023457 2.1451255431067108e-05 3.3142199777759745e-07 +Nadh dehydrogenase complex assembly 16 30 2.3903483652142987 0.0168323982978197 9.266990291262136 26.96359223300971 1.1245271541492263 0.3013677937017552 4.122702675359976 4.029157649894909 1.4460543016521823 0.3224564676521605 0.0304702276607945 0.2406936845278361 0.4274740864709498 0.0483010618227088 0.0059899182032361 +Regulation of response to extracellular stimulus 1 5 2.3884148981148434 0.016921226765876 1.0364077669902914 4.466019417475728 1.2416795343104177 0.2058666180593168 0.8221064046230258 0.7766686887277909 1.0462594039989206 0.2178110962907249 0.0432787476847939 0.0516364610584135 0.1018169846714528 0.0276231155809849 0.0971506673250001 +Retrograde transport endosome to golgi 10 39 2.385597131542097 0.017051418884975 8.844660194174757 34.00485436893204 0.6408100896550543 0.5235396612667444 4.365036019054001 3.8497226893137166 0.9745365654790862 0.3516062635557995 0.0425011473264693 0.3306605597140526 0.0467208448743291 0.0149319876934548 0.0021782131622251 +Protein targeting to membrane 12 39 2.3777452423301253 0.0174188556640961 9.03640776699029 34.86407766990291 0.8678999397376299 0.4369909067843477 3.776027437978551 4.807050937156168 0.9685770296783628 0.3476738150633759 0.021947188213695 0.3561784256622231 0.0584891686146332 0.0687674325027371 0.0014562736104889 +Regulation of macroautophagy 18 57 2.3668273227944514 0.0179413014612521 12.53883495145631 54.54368932038835 0.6601926076755246 0.5184966676512008 5.17189441564166 7.149617002477752 0.982640144191414 0.3711017134042489 0.0548989139117017 0.1354750356227081 0.0097166817293753 0.1053216544744746 0.0299194706135594 +Circulatory system process 26 77 2.3631713034023982 0.0181192920304296 17.152912621359224 72.00970873786407 0.7968086684699157 0.4206667688960129 5.8797345113877215 8.195718922280731 1.282615010632819 0.3676426088525382 0.1277421624597588 0.1100030290437554 0.2085225759419394 0.1314165938502621 0.0480962737006894 +Organic cation transport 4 5 2.3606186972654952 0.0182444787056204 2.191747572815534 5.524271844660194 1.626219676916526 0.1372808582950073 1.481153399412497 1.209546654977186 0.871004228766265 0.1892257790071234 0.1354499342184248 0.0963063052639835 0.1854358412925483 0.0901924811619011 0.0794376465838621 +Release of cytochrome c from mitochondria 8 18 2.360508979004823 0.0182498765174041 4.684466019417476 15.262135922330096 0.4193082596791256 0.5083980701856582 2.17386315704194 1.8032396146210607 0.903472393069956 0.3097282682815904 0.0311335520684521 1.0 0.3169879022746943 0.0671599559498881 8.125377290359248e-05 +Protein import 20 91 2.342699269311628 0.0191448075104041 18.941747572815533 84.88106796116504 0.6008949453203009 0.582747226306641 7.950789473798742 5.928615059974957 0.9194508312715092 0.3730411656244653 0.0963553906704955 0.0529845024550984 0.0288090143646809 0.1364029671177349 0.012414712664461 +Response to increased oxygen levels 2 9 2.3341378508805564 0.019588504898788 1.9563106796116505 8.939320388349515 0.9100937072347148 0.3197058737817761 1.2933864561055997 1.001798152387997 1.0059424935454593 0.2746313949658078 0.0223651585611987 0.0919337377678228 0.0008978593047678 0.0116756742779249 0.0705348016344186 +Ceramide catabolic process 4 8 2.322283627807179 0.0202176685295008 3.8592233009708736 6.531553398058253 0.1286784152295923 0.1423502941444668 1.429436503356119 0.7012295128365029 2.0219843992394857 0.2259194528389771 1.778722199929925e-05 0.0561990347849709 0.0057815105752346 0.0001405335592956 0.0001590313802548 +Positive regulation of cysteine type endopeptidase activity 11 31 2.3164513237871573 0.0205336392373234 7.196601941747573 28.478155339805824 0.6118231968344265 0.4994143481361404 2.711480107898675 3.3256882629722657 0.9483693928307184 0.340405399390541 0.1393566977085462 1.0 0.2139520870514039 0.0637395822669413 0.0286488046408713 +Regulation of nitric oxide metabolic process 6 12 2.310275729595593 0.0208728937299234 2.783980582524272 10.701456310679612 0.1430441353915724 0.5171013303945987 1.722054451404933 1.369110623206423 0.8984736114957514 0.280454644640389 0.2472401890511195 1.0 1.0 0.5315101420828222 0.0159032502878613 +Ceramide transport 2 5 2.310209941055348 0.0208765339470564 1.779126213592233 5.310679611650485 0.994079753441996 0.2057455404068654 1.027416031856974 0.785538294365343 1.3065287972688011 0.2361222749942 0.3342830117953164 1.0 0.1191939669275513 0.2721697661507766 0.0227185425065092 +Pigment metabolic process 5 28 2.306354284959659 0.0210908441767312 6.730582524271845 27.429611650485437 0.7330558837492486 0.3938325994367372 3.1680652652278396 2.973572406869117 1.1788232115476622 0.3357800616079686 0.0066289890252152 6.03917629279808e-06 0.0001846581304315 0.0020006005653745 0.0165908314289981 +Regulation of smooth muscle contraction 0 5 2.2924531131906143 0.0218795101657274 1.1262135922330097 4.169902912621359 0.2781306853839073 0.5171960524441427 1.0854698919901893 0.9705703409287478 0.9780989466031628 0.3196844872181871 0.5133658415211507 0.1049896535105009 0.2012104780589677 0.4301270919610729 0.682815470497098 +Response to nicotine 0 5 2.2841423717583407 0.0223631650799096 0.9684466019417476 5.080097087378641 0.5068538891293205 0.4736423969944768 1.262404284389805 1.3885425726317988 0.8599192085593864 0.2781778596016942 0.5429445681473749 0.1135912525516411 0.2166826538338764 0.4573561220916043 0.712992529293242 +Hormone metabolic process 13 29 2.275781049086183 0.0228591175442456 8.95631067961165 28.65776699029126 1.130508313948193 0.2963365150575847 3.9674689274001818 2.5345884681715156 1.346801337886388 0.3240077568826507 0.0298620734229399 0.3746890061856052 0.0145653075103282 0.008907043045769 0.0192471263691677 +Nucleotide transport 8 12 2.275649021512519 0.0228670247936246 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 0.0445840383189574 0.1178616319260966 0.2243071172363204 0.0239571113561098 0.0075122167669424 +Regulation of amyloid fibril formation 3 7 2.27563827523934 0.0228676685020916 2.2888349514563107 5.662621359223301 0.5261836595996398 0.3490055624244857 1.4817896559260575 1.2503440001723864 1.197683561482515 0.297347360341851 0.0432787476847939 1.0 1.0 0.0276231155809849 0.00138858926748 +Behavior 21 86 2.2694378045490584 0.023241715417916 16.990291262135923 75.04126213592232 0.2909440827671418 0.5405324846032677 5.526186812971979 8.403983472903677 1.109438409605415 0.3578193814797769 0.0742255612270311 0.3739570139316887 0.122004806153777 0.1183179292539205 0.0676218358508843 +Dicarboxylic acid transport 13 18 2.260707720534728 0.0237773620776973 5.718446601941747 16.097087378640776 1.1205667041867788 0.2998586575349944 3.584398436287638 2.226340822602054 1.0973546365412417 0.2986830136605488 0.0394625262322114 0.0172375696548913 0.0625314301217693 0.0801176308941427 0.0516637732040453 +L alpha amino acid transmembrane transport 9 11 2.2593066727974285 0.0238643151294795 4.480582524271845 10.533980582524272 0.7590361902351016 0.3223730555033793 2.606398335255894 1.1951807271273862 1.273814103695318 0.3116596719827348 0.0801033806596056 1.0 1.0 0.0444854600227105 0.0743636419116672 +Regulation of peptidase activity 26 87 2.257859420222573 0.023954425258529 17.567961165048544 78.76456310679612 0.2681055370567821 0.6519293611165848 6.220288033667961 7.048060158198876 0.8199709838080707 0.3419859398793775 0.0858423798533863 1.0 0.6439140052072462 0.0449452301043846 0.0029824486132487 +Embryonic heart tube development 1 6 2.256802918606664 0.0240203922970003 1.3932038834951457 5.800970873786408 0.4671790151602789 0.3328586203421327 1.1599097835626424 1.1943227471644264 1.1899911587922487 0.2586146658185882 0.4890741555492019 1.0 0.4045619729724357 0.3670688568616856 0.7368510761860215 +Endoplasmic reticulum tubular network organization 6 11 2.256798832318471 0.0240206477467859 4.150485436893204 10.555825242718448 0.8961707031484618 0.3171343629503343 2.1669796342432037 1.8339543060404635 1.2935176897309475 0.3199619326088047 0.0142767807743484 1.0 1.0 0.0073447144383531 0.0010145405611514 +Positive regulation of mitochondrial translation 1 6 2.2540855742528008 0.0241907850138998 1.8155339805825244 7.439320388349515 1.1233950947475233 0.2654033071264799 1.4295601388514203 1.5544197944414198 1.0052042080836443 0.2741718924063684 0.0762554308819813 0.0697581245313758 0.1362380906066266 0.0495157384890535 0.16360549489043 +Inflammatory response 10 73 2.251685334298817 0.0243421640981911 13.228155339805824 68.3883495145631 0.4116983048649594 0.5194837377797665 5.6022172704029956 8.769134982645609 1.0984550499812151 0.3566163019943059 0.491882161405143 0.1498123589191256 0.0539949318676087 0.2324059702572937 0.7114476441388089 +Membrane docking 8 31 2.246697472902157 0.0246593678726092 7.973300970873787 28.83252427184466 0.3013065671948621 0.638505559524285 3.967313754164099 3.197937811998676 0.8147042438070861 0.3288047187933706 0.3492272229556524 1.0 0.1411421437582085 0.2256891642594976 0.0464752879206614 +Negative regulation of mrna metabolic process 17 46 2.246517774880313 0.024670862313648 15.78640776699029 45.30339805825243 0.4317654752348391 0.5186468695555119 6.004287279655988 2.910090931551649 1.3207774317424965 0.3775544483756486 0.0231985454414817 1.0 0.5058832188962971 0.0296820907724347 0.0006596002166852 +Antigen processing and presentation 9 27 2.245994487468117 0.0247043610007984 6.201456310679611 22.17718446601942 0.8231471183465873 0.4220086818460768 2.970845032857872 3.056135613532617 0.9682333159777928 0.3245513416930483 0.0304702276607945 1.0 0.4274740864709498 0.0483010618227088 0.0059899182032361 +Negative regulation of rna catabolic process 10 31 2.2456678901913176 0.0247252883660233 11.186893203883496 32.42718446601942 0.419853700893663 0.5432159718224696 4.924332595678975 2.3133296381008863 1.0980554146273172 0.3596399931743501 0.0085731902348167 1.0 0.4330643878145832 0.0127222619547071 0.0017963005545976 +Vitamin transmembrane transport 3 7 2.243034760675241 0.0248945730342908 2.9344660194174756 6.094660194174757 1.6910321805591797 0.1136175735100163 1.344920850275403 0.8913122381585616 1.0580472895861666 0.1862049292817703 0.0009203602780865 0.0697581245313758 0.0003712110430798 0.000366006536683 0.0049176108076387 +Intrinsic apoptotic signaling pathway in response to dna damage 9 26 2.2394569180018467 0.0251262014959494 5.191747572815534 23.4004854368932 0.4729571891933678 0.5742196556826167 2.43550394585209 2.759326595293978 0.7661559213706911 0.3096443051481624 0.0810262579929451 0.3041527321586795 0.1648336472785623 0.0345747530672156 0.0102391615546744 +Autophagy of mitochondrion 14 32 2.2386246782001717 0.0251803471405374 8.643203883495145 32.55582524271845 0.5912176019297528 0.507260115546458 3.9310041488944902 4.499114265424183 1.01585008111736 0.3556742421157408 0.0846656520302021 0.3075216202298709 0.1682749782688163 0.0363101363561639 0.0757419688955735 +Mitochondrial atp synthesis coupled proton transport 6 11 2.231505399827509 0.0256476702342791 3.9927184466019416 10.769417475728156 0.5022502301293951 0.29867761594221 2.4440229028906213 0.8937412640542226 1.3849431163992842 0.2834040324316194 0.01674854618918 0.0032958763634803 0.012905013470629 0.0086586519898169 0.0098193480789534 +Glycolipid catabolic process 4 8 2.223770767630908 0.0261638711284815 3.6310679611650487 6.451456310679611 0.1059933679561382 0.1697430158083476 1.434595381284437 0.7664524352299261 1.9023109688101565 0.2365791262889882 1.778722199929925e-05 1.0 0.1105474823156849 0.0001405335592956 0.0001590313802548 +Regulation of water loss via skin 3 6 2.2157469016571363 0.0267088408123004 1.3980582524271843 4.95873786407767 0.4829857617931532 0.4190090745011622 1.132827083225922 0.8422959602674207 1.0405700816787415 0.2964107522750627 0.0009203602780865 0.0697581245313758 0.0090253131212995 0.0050923434600555 0.0049176108076387 +Negative regulation of nik nf kappab signaling 1 5 2.2059692762345096 0.0273861509837927 0.7451456310679612 3.71116504854369 0.620796615390586 0.3908602148474796 0.9324780265795692 0.9433320421203856 1.0539692719554044 0.2872576560154498 0.412684967450451 0.0786913117950012 0.152955667850895 0.3400030327298383 0.5719289219770226 +Negative regulation of leukocyte migration 2 7 2.205553708175678 0.0274152633545459 1.5655339805825244 6.388349514563107 1.0839414642274992 0.2862432737648586 1.19995002173864 1.2770035444730965 0.9459956297737524 0.2624453160295969 0.0120270758321215 0.0026008925831016 0.000453663444764 0.0061570039439817 0.00630824692371 +Cellular response to reactive nitrogen species 2 7 2.199221697345022 0.0278621622636106 2.1650485436893203 7.007281553398058 0.704490730091036 0.4621610896845695 1.550741052909057 1.0369135438534465 0.8122040116731231 0.3119296534732217 0.3548108655020613 1.0 0.1277572387780678 0.2897526236095206 0.0278921605814954 +Response to nitric oxide 2 7 2.199221697345022 0.0278621622636106 2.1966019417475726 7.133495145631068 0.679168344832026 0.4714973348756168 1.5773543373723289 1.1316902117688077 0.8115312793316939 0.314104254155695 0.3548108655020613 1.0 0.1277572387780678 0.2897526236095206 0.0278921605814954 +Neuronal action potential 0 5 2.1954085588766645 0.0281343037099659 1.2475728155339805 4.521844660194175 0.5642353900817267 0.463764525154269 1.1328582855694418 0.6169203935566157 0.8757196856996938 0.2995166866793592 0.1448120450870512 1.0 0.047623940504538 0.1149745986461117 0.2207303711304172 +Protein import into peroxisome membrane 1 5 2.194093572686932 0.0282286832435545 0.9924433249370276 2.6448362720403025 0.7786051618991183 0.383741398211786 0.8619837263666495 0.9973793297183008 1.144457080844935 0.3054932310074545 0.0130639252547178 1.0 0.0568757538574934 0.1363381791325428 0.0310935661517569 +Endochondral bone morphogenesis 2 5 2.189083908169722 0.0285907419060595 1.6480582524271843 5.594660194174757 0.7038217123315962 0.3729755664973352 1.1864612949328115 1.0785960989759678 0.9833570305213049 0.2787707264141815 0.5968328668571221 1.0 0.2467424796819782 0.5079876539292768 0.1652047572335966 +Regulated exocytosis 13 36 2.187092493984091 0.0287357724831629 9.385922330097088 34.342233009708735 0.5889869251407832 0.528096964379338 3.868480531815476 4.573760415025692 0.9122431884356956 0.3457208176316948 0.7303650693689857 0.4463627535095094 0.6980596213140103 0.7977158209973941 0.2424849321942219 +Transition metal ion homeostasis 5 24 2.185900663899616 0.0288228736706301 6.640776699029126 24.57281553398058 0.9239194315613378 0.3015424973151205 2.934079531592402 2.8081087224394015 1.2471169312381896 0.2974369333820005 0.0364797455744623 0.0564048148733258 0.0075298180020017 0.0437821029600269 0.0936686726213597 +Regulation of protein catabolic process in the vacuole 0 5 2.185623519698266 0.0288431604345897 1.2014563106796117 3.3762135922330097 0.3553822840909967 0.3561494889357127 1.140898051797836 1.3189129213804007 1.3434272672921512 0.3030873575434169 0.2912537743602003 1.0 0.1018169846714528 0.2356930071839008 0.4223814846322101 +Regulation of lysosomal protein catabolic process 0 5 2.185623519698266 0.0288431604345897 1.1820388349514563 3.344660194174758 0.359320837781623 0.3612070071329659 1.1335003430162958 1.3137235419699895 1.333216779855555 0.3035682445298419 0.2454527277981396 1.0 0.0841007109914387 0.1973959389561772 0.36173840478418 +Cellular response to oxygen levels 13 39 2.18477680745888 0.0289052153532998 8.393203883495145 36.271844660194176 0.9126927578207408 0.4163034805851183 3.607671495386698 4.048118764224637 0.9088125816374436 0.3418533733797396 0.1159564424959476 0.4072806445693771 0.0039499040991049 0.0463775215794435 0.0371199717135117 +Vesicle organization 21 104 2.181035798481089 0.0291807687737144 22.83495145631068 92.86893203883496 0.0463488900678319 0.7096208745167389 8.867796091584163 11.766015972671791 0.8083581851270146 0.3222323416126856 0.4655619727168704 0.6911526504753159 0.2065020299591853 0.2270205111875539 0.0069277982947671 +Regulation of b cell apoptotic process 1 6 2.180891919859363 0.0291914115035292 1.2888349514563109 4.143203883495145 0.4712803824401109 0.4838259091452473 1.0979113453615192 1.1000341685710282 1.0371325316664826 0.3279009485506359 0.0589581135287866 0.0607401038440192 0.0067896670197663 0.0379575415698398 0.129364196063302 +Regulation of b cell activation 2 18 2.1803759524463984 0.0292296051858467 4.223300970873787 16.516990291262136 0.0577495350333673 0.5689697369892935 2.5301369502630555 2.1860552471506893 0.9138021371463246 0.3063589445117784 0.3067791184571263 0.2624522374738631 0.0231701844530087 0.1942870876140905 0.5976883225726286 +Collagen fibril organization 2 7 2.178523289612967 0.0293671002625888 2.75 8.449029126213592 0.7618465155681635 0.4237593014631459 1.546409872946248 1.4346015410823785 0.9057772992250752 0.3095171034083678 0.0490509502921506 0.1221118561195742 0.2318581098993339 0.1374615323876937 0.14168603717257 +Chloride transport 7 12 2.178192583610013 0.0293917019931015 4.33252427184466 12.12621359223301 1.0302584084066435 0.2341882174183942 2.3624510960969567 2.26059366569241 1.2797232968088257 0.2563105728143979 0.0801033806596056 0.1471951297158956 0.0405463165390607 0.0444854600227105 0.0046379242911556 +Mating 1 7 2.1778374820410717 0.0294181382856455 1.296116504854369 4.12378640776699 -0.0749270475296282 0.3679325751810022 0.937194981329158 1.089097440971999 1.345984464291908 0.2988095708193542 0.0674209136026369 0.0652597674910206 0.1277572387780678 0.0435926191526008 0.1462762019757018 +Phosphatidylserine metabolic process 2 5 2.1771820944224016 0.0294669837301917 1.6116504854368932 4.798543689320389 0.5449831042779167 0.333458204805222 1.1531553142618924 1.1765086639888198 1.1706570072177929 0.2634993979961211 0.3939928003913119 1.0 1.0 0.3236592382947187 0.1812716861639223 +Regulation of steroid biosynthetic process 3 11 2.169743065111616 0.0300263156613447 3.186893203883495 10.259708737864075 0.6168896095149775 0.3174156062343823 1.783561142158544 1.373475469974866 1.265753415239616 0.2847701277650337 0.3276438993956789 0.1675604235637086 0.3102657432506607 0.2332121755087385 0.2812242430558347 +Protoporphyrinogen ix metabolic process 1 5 2.1640912456711434 0.0304573472521487 1.5218446601941749 4.599514563106796 0.185664118708611 0.5137971335636379 1.215597857281275 0.7121005146689612 0.9347185130238812 0.294055533641897 0.2687105901139324 0.0470522829573702 0.0930016660897952 0.2167775624926856 0.0820486275159116 +Positive regulation of chemokine production 4 8 2.158090455644501 0.0309207996751585 1.703883495145631 7.002427184466019 1.1308330497685224 0.261365768238967 1.2206493839204828 0.948936007151574 0.9251734036107908 0.2478284645013121 0.0324772913294791 0.1049896535105009 0.0206800818926893 0.0172025832638257 0.0986013223955862 +Locomotory behavior 8 31 2.1518071392586315 0.0314125473301607 7.186893203883495 29.01456310679612 0.367578136549174 0.4129867938447028 2.855164467106169 2.964970497634466 1.254834886476281 0.3178953925587394 0.0270379161795498 0.3685774959165274 0.0648492807338132 0.0271532501248917 0.0411573249463058 +Regulation of protein exit from endoplasmic reticulum 7 9 2.1508687668656385 0.0314865593983839 2.487864077669903 6.131067961165049 0.614536574202818 0.458469843561175 1.597129798474628 1.7824129563144424 0.9381550143256092 0.3206976005104832 0.4653827497861043 1.0 1.0 1.0 0.01439805670462 +Negative regulation of glycoprotein metabolic process 3 5 2.1506086140025897 0.0315071048501947 1.1237864077669903 2.9150485436893203 0.4709960836391295 0.3904285331302831 0.8655865248767802 1.0928126832857985 1.3043889305991798 0.3156095962580754 0.0294966217370324 1.0 1.0 0.0186627473263165 0.0677640175569944 +Lipid biosynthetic process 54 155 2.149741495401775 0.0315756682004988 38.012135922330096 141.7257281553398 0.5620793375816577 0.4367444072022249 15.729119254593195 17.314902336322657 1.553306672697969 0.3832082090559359 0.0014397780561473 0.1463513896823768 0.0026870897089852 0.000606787084917 4.366211205661094e-05 +Cellular response to biotic stimulus 15 38 2.1488581584410738 0.0316456454812581 8.070388349514563 35.616504854368934 0.7964477296470692 0.4798420500319036 3.1871094803090645 3.824235365857021 0.8467616012566905 0.3489796792314515 0.0597124418957146 1.0 0.0971065943925469 0.0555655068618841 0.0988928907574591 +Diol metabolic process 4 7 2.148129555777801 0.031703464880143 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0120270758321215 0.0742352733278267 0.0102498345034834 0.0557098434243155 0.000745702459351 +Diol biosynthetic process 4 7 2.148129555777801 0.031703464880143 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0065763731833925 0.0607401038440192 0.0067896670197663 0.0379575415698398 0.0002481332774246 +Secretion 50 166 2.1466303321320392 0.0318227231358145 33.99271844660194 147.42233009708738 0.4048828366720226 0.7039215372882776 10.476160889322964 16.385711464618055 0.7463810424968602 0.3447407367793494 0.5477151873482792 0.1758057884162462 0.4582414195946155 0.670015663516128 0.0238642364887674 +Mitochondrial calcium ion transmembrane transport 6 9 2.140368807488892 0.0323249732867789 3.4684466019417477 9.04126213592233 0.7792467211325117 0.2463779000555085 2.196969341156949 1.2010296388602075 1.3738174116662032 0.263849842646199 0.0120270758321215 0.0742352733278267 0.144637307685789 0.0557098434243155 0.000745702459351 +Positive regulation of macroautophagy 3 20 2.140337655550196 0.0323274889315738 5.058252427184466 20.34223300970874 0.7197293510270528 0.4154159089925248 2.5734840677494253 3.836065802213299 1.0387053871978371 0.3265560923975395 0.112911215803706 0.0335548880884004 0.1151189883762866 0.1760149897618766 0.3339856150584848 +Phosphatidic acid metabolic process 2 5 2.134841931661075 0.0327739238679094 2.2233009708737863 6.235436893203883 0.8816881639607732 0.2856229767394486 1.614148841412113 1.5439850574626743 1.1927985254107716 0.2824496640110863 0.1901881882333377 1.0 0.2243071172363204 0.1292409073430241 0.1303826157459173 +Atp synthesis coupled proton transport 6 12 2.134808669696226 0.0327766418335189 4.067961165048544 11.769417475728156 0.4798560195228825 0.3249136059986872 2.5150503707528173 0.8937412640542226 1.340203957668315 0.2941072770431484 0.0223651585611987 0.0040679264544396 0.0158256043387446 0.0116756742779249 0.01439805670462 +Regulation of phospholipase a2 activity 0 5 2.127923832327949 0.0333433992561236 0.9441747572815534 3.325242718446602 0.6615657912122316 0.3335940096773371 0.936990663475616 0.7247655726250474 1.2538248542138828 0.2855061836907117 0.1448120450870512 0.0238038053541035 0.047623940504538 0.1149745986461117 0.2207303711304172 +Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0 5 2.1273123689070066 0.0333941377284592 1.1650485436893203 4.774271844660194 0.4614524153215229 0.4159478485874965 1.135029937406304 0.939953626145654 0.9993123928873244 0.2814891640395888 0.2454527277981396 0.0424464003246627 0.0841007109914387 0.1973959389561772 0.36173840478418 +Early endosome to golgi transport 5 8 2.126224669365525 0.0334845569512773 2.320388349514563 6.650485436893204 1.001706299736163 0.3202433583076141 1.526233973035193 1.1381191933763375 0.8656979853859356 0.2689019049302471 0.005175564892058 0.0561990347849709 0.1105474823156849 0.0025975272437437 0.0001590313802548 +B cell homeostasis 2 6 2.1207449295204004 0.0339432733247828 1.4757281553398058 4.536407766990291 0.4480782451254183 0.4467870426707374 1.122104993046938 1.5204542974451043 1.0822082623347038 0.3160935496142801 0.0288824454338437 0.0049155620827658 0.0011959433226113 0.0152248647419399 0.0888008652079453 +Deoxyribonucleoside triphosphate catabolic process 1 5 2.1193871753156426 0.0340577597405364 1.3131067961165048 4.985436893203883 0.3582467332448406 0.3438147591003742 1.2253483983473652 0.7035151362894804 1.2506842424472815 0.2759561596807582 0.1967019277312726 0.0331691185540615 0.0660385900079411 0.1571881112173651 0.042147958906207 +Energy derivation by oxidation of organic compounds 49 130 2.1151609604290096 0.0344162310206777 30.652912621359224 122.18932038834951 0.2541815110246533 0.5071130371174295 12.61138398748304 8.311769788309597 1.4201467433346076 0.3884313364311733 0.0013737166227751 0.0059885984942463 0.0093039035177462 0.0008003980868384 5.0100039077165045e-05 +Atp metabolic process 37 114 2.1110290831904184 0.0347698121445332 25.97087378640777 107.69417475728156 0.2650120939459569 0.5409439866831242 10.270805368899644 8.059768543771504 1.2580915670575048 0.3757529915372982 0.0008092866740623 0.0032938072453758 0.0043874518009505 0.0001782525425185 0.0005985043795057 +Sulfur compound transport 2 9 2.107843575772377 0.0350445221902233 3.504854368932039 9.429611650485436 1.339223354728307 0.2167503093092372 2.046184165461596 2.1092484385198076 1.0728301411615704 0.2604171804663498 0.0801033806596056 0.0108643857486399 0.0405463165390607 0.0444854600227105 0.2151867556135544 +Negative regulation of transmembrane transport 9 26 2.1048984271098465 0.035300150651218 4.915048543689321 20.038834951456312 0.539232326403696 0.5077941070021844 2.6236539308948164 2.892649976298608 0.8428552268580063 0.3052620790205636 0.8657787262273546 0.2660187864050092 0.4654893004054254 0.7915335109512663 0.011945414705558 +Amyloid precursor protein metabolic process 8 25 2.100466974424433 0.0356877828334121 5.91747572815534 20.04368932038835 1.2306110398413417 0.2828388345239639 2.574706211328507 3.0661056512526157 1.0127867956133585 0.2841981221806073 0.026591573854945 1.0 1.0 0.0102355224712358 0.0012203555248968 +Membrane protein proteolysis 8 13 2.093169932677635 0.0363339877581572 4.138349514563107 11.781553398058252 1.0093176076341577 0.3069750059979975 2.078037067185485 1.3902746514167437 1.0484204695389652 0.2877212872591311 0.3502876200553227 1.0 0.3236452024265956 0.2511786735203468 0.0432084674189714 +Regulation of long term synaptic potentiation 5 7 2.092707072470632 0.0363753115318901 2.191747572815534 6.026699029126213 0.6105178624452509 0.3860292464291884 1.2788913032023987 1.4948993461258857 1.1199694698848182 0.3107967468650517 0.1678952927885492 1.0 1.0 0.4439075633632242 0.0271057364081029 +Regulation of transport 111 347 2.091366526506418 0.0364952204166766 64.95873786407768 311.3543689320388 0.199755337930638 0.8517569288715414 18.30421847391998 33.62955899493757 0.556704960232788 0.2772693072558876 0.5095269240018802 0.2625959586563441 0.3775961023173378 0.4199880104863329 0.0158289682907748 +Carbohydrate derivative biosynthetic process 51 168 2.0883449965544334 0.0367667252563934 34.89320388349515 157.5752427184466 0.1333925495981435 0.673754283550047 12.337615244823663 15.61138085883912 0.9078866636106409 0.345023479104077 0.0008683712726334 0.0132045488557229 0.0063424321392034 0.0003725192997035 0.0015994998172262 +Regulation of autophagy of mitochondrion 3 15 2.088185035691972 0.0367811466451928 3.83495145631068 15.269417475728156 0.5599037905354275 0.4319133125136808 2.249474965186929 2.2839109385500524 1.0076019915675485 0.3108342800197468 0.0160815615877132 0.1430638950507344 0.2685353106225043 0.0069928111010265 0.0678374957909117 +Outer mitochondrial membrane organization 1 5 2.084831350055478 0.0370846119264789 1.4296116504854368 4.956310679611651 1.1531610290328034 0.2630141305877053 0.9963023114429655 0.2044029443827893 0.89744850896642 0.2676384061848394 0.0088892784124033 0.0238038053541035 0.047623940504538 0.0055254488719224 0.0214122317398669 +Regulation of hormone metabolic process 2 5 2.081986073357168 0.0373437418169948 1.9199029126213591 5.327669902912621 0.9387613573830266 0.3058102715557096 1.1578738425382251 0.5676654694542113 0.9983912186719198 0.2773016546183636 0.4653827497861043 1.0 0.1774332758731671 0.3867116248199588 0.2539261987860491 +Protein insertion into er membrane 6 13 2.081637359802685 0.0373756062194754 4.451456310679611 12.691747572815531 0.9645901040516046 0.3077872373135509 2.16101217194965 1.431147904526304 1.1733171268605926 0.305304417896891 0.00416112186728 0.1006582454154426 0.0190005699483642 0.0152248647419399 0.0004920431328091 +Copi coated vesicle budding 2 5 2.081612795882977 0.0373778516692651 1.7354368932038835 4.359223300970874 0.2179065168211083 0.3721057821405019 0.913972739389764 0.7051043981373246 1.2311252143625453 0.2964555974181374 0.1711616690515185 1.0 0.0568757538574934 0.1363381791325428 0.0020495629143173 +Regulation of hormone levels 23 70 2.075780343012455 0.0379142712013018 15.682038834951456 62.25485436893204 0.7754141622249116 0.4638741971732045 6.630568201753413 6.49574922456989 1.111399769110166 0.3798141702267368 0.3528179889493603 0.6523759430413363 0.1599930923503212 0.2702565003392003 0.258351616433187 +N glycan processing 1 5 2.0749640600847696 0.0379898658027837 1.529126213592233 3.5485436893203883 -0.0117057048468242 0.5582969247245594 1.0688103420050374 1.0168831187592096 0.9334443002763886 0.3098462372201576 0.3131041734647267 1.0 0.1105474823156849 0.2541534411772372 0.1129571724371578 +Response to food 3 6 2.074878140463532 0.0379978301269126 1.720873786407767 5.783980582524272 1.3281223897944048 0.1823213242558801 0.9790282548915298 0.8299231919143666 1.0823564620426191 0.211054619984942 0.0589581135287866 0.0607401038440192 0.1191939669275513 0.0379575415698398 0.0027834726260547 +Regulation of glycoprotein metabolic process 7 15 2.073151883854941 0.0381581467020446 3.592233009708738 10.70631067961165 0.6804974065630551 0.4353046559123504 2.03935499608955 1.985055569049905 0.9883671343018048 0.3255557758909779 0.2128446667457567 1.0 1.0 0.1457934990596532 0.0448872219881859 +Glial cell proliferation 3 8 2.071527260661273 0.0383095496096121 1.6262135922330097 5.412621359223301 1.1035845317400614 0.2421873681292294 1.0594430818589295 1.1842969002295405 1.0977939547178823 0.257309212646388 0.0324772913294791 1.0 0.2012104780589677 0.0172025832638257 0.0234644839392777 +Collagen metabolic process 4 11 2.0679931642502987 0.038640665892428 2.587378640776699 9.830097087378642 0.5446744382123272 0.4689909171837226 1.5071467037844224 1.48463554754042 0.8983431921228839 0.2959543118042154 0.0160815615877132 1.0 1.0 0.0411512789917762 0.0181161163925661 +Sterol transport 6 27 2.0678540881795744 0.0386537457785916 5.516990291262136 23.23058252427185 0.3564989162781894 0.4550431454343515 2.7566693478017315 3.339632072416373 1.1016145306573315 0.3225081354886266 0.0179815096442294 1.0 0.028249351231176 0.0814773755217055 0.0464752879206614 +Regulation of release of cytochrome c from mitochondria 7 14 2.0626434520676504 0.0391465161668871 3.6310679611650487 10.805825242718448 0.7924389389582319 0.4006886058463786 1.815469081442188 1.3603843861930187 0.9712392086725492 0.3199873643457663 0.0689739385274077 1.0 0.2613412907301976 0.1713585638073601 0.0005860509424053 +Negative regulation of amyloid fibril formation 2 6 2.061917883298342 0.0392155546309345 2.1529126213592233 4.890776699029126 0.3569908231055533 0.4009987139403995 1.2573729209219855 1.077218811389963 1.1293664882470678 0.3015190208545801 0.2454527277981396 1.0 1.0 0.1973959389561772 0.00771353919978 +Electron transport chain 31 72 2.0612282672703657 0.0392812679677718 19.550970873786408 67.77184466019418 0.3712062453977176 0.4872800905659868 8.486701420407794 5.37626783377928 1.3790913022045077 0.3735693075609537 0.0510816474967504 0.0253511637379553 0.009139466057967 0.0405739186343233 0.0048671186790536 +Positive regulation of protein exit from endoplasmic reticulum 4 5 2.061026855402556 0.0393004780862811 1.7014563106796117 3.842233009708738 0.6319527754438191 0.4528969328253339 1.0729226103046268 0.876811779781035 1.0096007730201175 0.3294914749708005 1.0 1.0 1.0 1.0 0.0053334351931861 +Amp salvage 0 5 2.060339396290717 0.0393661061623202 1.91747572815534 4.635922330097087 0.265573089223418 0.4091186067198797 1.492045392504656 0.515272454828754 1.1444474328484808 0.294450018392828 0.1448120450870512 0.0238038053541035 0.047623940504538 0.1149745986461117 0.2207303711304172 +Proton transporting two sector atpase complex assembly 3 6 2.059936054703189 0.039404654337406 1.7432098765432098 4.6839506172839505 1.079697689782964 0.2705190312822739 1.1688274457451555 1.1775111637565157 1.0292886485906785 0.2668917829180481 0.3548108655020613 1.0 0.1277572387780678 0.2897526236095206 0.0037486095651754 +Neuron recognition 2 6 2.0548483622884826 0.0398936533324711 1.9368932038834952 6.189320388349515 0.7447638338644241 0.3705616592284931 1.1064234596616862 1.175429078554095 1.011644937344681 0.2892876339238009 0.0537276740302863 1.0 1.0 0.0291459656321865 0.1533018949933901 +Antigen processing and presentation of exogenous peptide antigen 3 5 2.054566552897601 0.0399208890215956 1.6067961165048543 4.686893203883495 0.987028524507588 0.2895214995402835 1.1019631322504793 1.05964046762731 1.0509935492639806 0.2645206747413269 0.4653827497861043 1.0 1.0 0.3867116248199588 0.631511633602643 +Cellular sodium ion homeostasis 4 5 2.053973252604311 0.0399782805638802 1.7645631067961165 4.279126213592233 0.3130666300494188 0.4596282540439977 1.2029117398149052 0.6440551245721169 1.0188577401619887 0.3109798964466274 1.0 1.0 1.0 1.0 1.0 +Chloride transmembrane transport 4 5 2.0539732526042926 0.0399782805638819 1.9271844660194175 5.497572815533981 1.0121969151812915 0.2503571453769561 1.6864793094247907 1.5080669592016671 1.1003731395705292 0.2453144412674818 0.412684967450451 1.0 0.152955667850895 0.3400030327298383 0.1992011927715255 +Protein localization to organelle 93 356 2.053479320357963 0.0400261133451378 67.3495145631068 323.95873786407765 0.2673038377247629 0.817015428896562 19.766210620364816 30.728939371736654 0.7017218037327799 0.31039729979455 0.0105509273351995 0.0223887443305945 0.0245915261697326 0.005637538318811 0.0004451839971052 +Leukocyte homeostasis 6 15 2.053359876472825 0.0400376876704087 3.4029126213592233 12.177184466019416 0.5028432712633871 0.4794963594230453 1.9872875748080177 2.4917658251002113 0.9479568975066928 0.3126900449378977 0.0754715823975887 0.0257535715284909 0.0139156518076104 0.0362911702166911 0.1072426750643267 +T cell differentiation 3 25 2.050012947761375 0.0403631673333499 5.021844660194175 25.37378640776699 0.4350228719786409 0.5180951440553598 2.967789621588004 3.0760730597535333 0.9025381406717272 0.3196787714458526 0.5145724724572249 0.114689393659792 0.1131806930644622 0.3343347396890538 0.7075153312671647 +Inorganic anion transmembrane transport 7 9 2.0469585185371204 0.0406621575974253 3.4101941747572817 8.983009708737864 1.1245392058053427 0.2357455210082705 2.3748669786284156 1.7214248641786654 1.1968417731555627 0.2697184972505711 0.2242694495123563 0.1305522111527444 0.031964215627013 0.154226710893935 0.1652047572335966 +Mitophagy 11 16 2.045220070838296 0.0408331666021986 4.174757281553398 14.737864077669904 0.7026339988268726 0.4220360300693995 2.5842209186951752 2.0501535109396865 0.9566781806577936 0.318538155650451 0.0689739385274077 0.1389130578490434 0.2613412907301976 0.0379489226270714 0.0616223233666864 +Adult behavior 7 22 2.0436334529474443 0.0409897718831477 4.924757281553398 19.364077669902912 0.6031935344655648 0.4116465050786389 2.137657889318908 2.190772988063693 1.071812274679601 0.3090358289458393 0.0146419067967543 0.2695684389372801 0.1312354716944213 0.0200399882581909 0.0130614889048102 +Cdp diacylglycerol metabolic process 2 5 2.040810745095599 0.041269642127705 2.4393203883495147 6.388349514563107 0.0386959777105354 0.4087752339915881 1.6066329515606936 1.579498566792564 1.18423584316981 0.2981361461643844 0.3747076822525905 1.0 1.0 0.3069124011154697 0.0336357980244025 +Regulation of secretion 30 102 2.039812226611569 0.0413690315769468 19.521844660194176 89.43203883495146 0.3107106293169513 0.7189453252223079 6.646190857017904 10.524485676543694 0.6342572440447461 0.3131519415494544 0.6480701568253915 0.3963415280031773 0.5214310964600188 0.6832131032627471 0.0963444391375852 +Cerebellar purkinje cell layer morphogenesis 2 5 2.03977056467908 0.0413731828788666 0.9805825242718448 3.046116504854369 0.5202066442313834 0.3957986053011061 0.967737653251046 1.192740772143476 1.2436080958504707 0.3013799435192484 0.3131041734647267 1.0 0.1105474823156849 0.2541534411772372 0.4505109675601652 +Regulation of leukocyte migration 11 31 2.033427895281444 0.0420093114579875 6.080097087378641 26.6504854368932 0.4712165673240142 0.5560717407414059 2.980664549328318 3.842679935245632 0.8934424673809059 0.3310773445531978 0.1872372451113385 0.0479057539651017 0.0338721796728873 0.0994768290011166 0.143549387276975 +Vitamin transport 3 9 2.0317078004789084 0.0421832457666158 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 0.0057593610144797 0.1093006244161378 0.0015498580582828 0.0024022577840735 0.0271057364081029 +Membrane protein ectodomain proteolysis 5 11 2.0308977535097723 0.0422653677282673 3.2815533980582523 9.42233009708738 0.914660566901433 0.3175120830558543 1.6482852268027584 1.2623319489295757 0.9882621955102872 0.2679281534911034 0.2472401890511195 1.0 0.2613412907301976 0.1713585638073601 0.0159032502878613 +Lymphocyte homeostasis 3 12 2.02525182137301 0.0428415129208721 2.6140776699029127 9.157766990291265 0.5015073935560286 0.4550844260550281 1.7177248086463766 2.3424870328572864 0.9807186663047854 0.3016646201978763 0.0286114952840351 0.0142466262053111 0.0058560324261939 0.0128293519549119 0.0356460972875996 +Calcium import into the mitochondrion 5 6 2.022610679494264 0.0431133022732597 2.4563106796116503 6.04126213592233 0.8091317576129835 0.2214807715451704 1.7082137325011066 1.2010296388602073 1.3762222767333927 0.2421218388926935 0.050899384243609 0.0561990347849709 0.1105474823156849 0.2541534411772372 0.0020033682110678 +Positive regulation of mitochondrial membrane potential 2 5 2.022308438254973 0.0431444974293602 1.364077669902913 3.8592233009708736 0.466365083303736 0.5595064518974401 0.9621329832525916 0.6999218948386602 0.7924469360841313 0.3081726674594855 1.0 1.0 1.0 1.0 0.0053334351931861 +Apoptotic mitochondrial changes 14 32 2.0218356932272568 0.0431933290050425 8.33495145631068 31.9126213592233 0.3104951463965997 0.5709370276570955 3.5539451273925566 2.6332703138780773 0.8593316992754738 0.3196919958634499 0.0774724656304003 0.3007677906227077 0.1614053437321197 0.1032816849165518 0.0029540076202437 +Response to endoplasmic reticulum stress 34 89 2.020964530132804 0.0432834369867749 20.766990291262136 81.87135922330097 0.3895578367391949 0.6272162805638101 7.658618957730667 6.11384352257493 0.925049322897134 0.3624458148773257 0.089930973822187 1.0 0.129783031482388 0.3526982228582132 0.0345995264236448 +Neurotransmitter secretion 9 21 2.019986158065521 0.043384823339827 4.878640776699029 19.800970873786408 0.4739837619437216 0.5379742436571602 2.5178643472114657 2.5013004441236206 0.8040908235944773 0.3018218439933647 0.7238979658338713 0.3274019772455256 0.552149589688304 0.8661154321407631 0.2084680944013595 +Long term synaptic potentiation 7 11 2.0141944844470885 0.0439891185494876 3.012135922330097 9.730582524271844 0.4069972937780292 0.4936148854997918 1.5319726166057843 1.7661148877091215 0.9317897164603502 0.2968501206773379 0.3947303098632202 1.0 1.0 0.6593533907576883 0.1644709145443467 +Regulation of anion transport 5 14 2.0123573522057794 0.0441822807369094 3.657766990291262 11.50242718446602 0.7713855446015195 0.3761489496061844 2.0089273726107977 1.6987985280405251 0.9512307489218268 0.2850669663772418 0.2702860533260499 1.0 0.2756599666896902 0.1887844423268079 0.0205229364106292 +Alcohol biosynthetic process 11 34 2.0108827936413385 0.0443378382014301 9.344660194174756 36.09466019417476 1.0726679306851277 0.3539682718575088 3.792896481514287 3.1078151772256564 1.1587776417647702 0.3419459456532639 0.0538544708293801 0.0667099047189351 0.0539250432324065 0.0613062198602933 0.0010815371106456 +Mitochondrial electron transport cytochrome c to oxygen 5 6 2.0078264700829607 0.044661734964466 2.6189320388349513 6.021844660194175 0.7576771538928655 0.3133819177040797 1.4641113893518565 0.9306060741204804 1.2097595052740109 0.2966582872605096 0.050899384243609 0.0561990347849709 0.1105474823156849 0.032628233248221 0.1129571724371578 +Negative regulation of intrinsic apoptotic signaling pathway 15 34 2.007311394444048 0.0447165166500549 7.072815533980583 32.73543689320388 0.2261673899039709 0.6515378432875337 3.2388027925576277 2.557191753367991 0.7098878685633335 0.2932855271781135 0.074004914255373 0.297366720714231 0.1579906452537346 0.0312610879309806 0.0026677547140881 +Regulation of multicellular organism growth 7 16 2.00699597762894 0.0447500912788692 3.679611650485437 14.067961165048544 0.6235984614772049 0.4457844002979414 1.844506891943582 1.9756386993416857 0.857961107337238 0.2839539709235323 0.0040775097697983 1.0 0.045127039841821 0.0014099836558107 0.0062617463102783 +Positive regulation of leukocyte proliferation 3 18 2.005575827485915 0.0449015230578393 3.861650485436894 14.71359223300971 0.6007881424807215 0.4761380762722816 1.9750347653754128 2.1890082226375087 0.9342511129724644 0.3127219346815347 0.1028855434573013 0.2443632781182481 0.1088269092294783 0.0509365284789281 0.3116472395700642 +Nervous system process 38 114 2.00446294891801 0.045020492024125 23.060679611650485 100.46844660194176 0.466210961761844 0.5050785047376438 7.1617042179301365 12.55034423055404 1.1784062094355452 0.368401069133876 0.4978100218340014 0.3150553002675424 0.2077806888459291 0.6620310610497621 0.4356796360177023 +Lipoprotein localization 3 5 1.996467833373865 0.0458830236614018 1.7451456310679612 4.762135922330097 1.33870340128666 0.2150435313503844 1.1193794779630346 1.3835803073772095 0.999398972942542 0.2555578059866495 0.3131041734647267 0.0561990347849709 0.1105474823156849 0.2541534411772372 0.1129571724371578 +Collagen biosynthetic process 1 5 1.9958396430000784 0.0459513801907465 1.1262135922330097 4.106796116504855 0.6981430842153152 0.4242236639688965 0.8969160934280322 0.7195281808878056 0.9180983542730824 0.3058088763919501 0.0949181274262904 1.0 1.0 0.0621585272883563 0.1992011927715255 +Regulation of necrotic cell death 2 11 1.9948729805207552 0.046056735101573 2.6771844660194173 11.71359223300971 0.2977530378262362 0.4578180986081704 1.5454800476301118 1.252380145124011 1.0198350476395044 0.2956255904252384 0.0490509502921506 0.0073558029266518 0.0279813079733609 0.0264830942684438 0.14168603717257 +Anatomical structure maturation 11 33 1.9948534019533604 0.0460588710366782 6.815533980582524 30.893203883495147 0.3841260505655395 0.5416451005267833 3.09006416754166 4.620895179443306 0.9281404590939007 0.3269797675509184 0.1395589197436265 0.4243503559946278 0.0990612642216925 0.2960293064330963 0.1030303123093005 +Regulation of mitochondrial gene expression 1 11 1.9946017182960725 0.0460863360405114 2.594660194174758 11.4247572815534 0.8803116051858394 0.3443222138925089 2.2226265034531534 1.9350293365530056 0.991093358800792 0.2980671372776958 0.2014791672677182 0.1221118561195742 0.2318581098993339 0.1374615323876937 0.3807987055783595 +Entry into host 5 35 1.9907537404913664 0.0465079673497346 7.968446601941747 31.24514563106796 0.6061616104105989 0.3954837799611526 3.566493820193545 3.4119437173329663 1.31706945612869 0.333413728218646 0.0668842579486905 0.3624074851394556 0.2282562036879738 0.0740089890485984 0.2986773783837245 +Steroid biosynthetic process 16 45 1.9839197333500544 0.047264788687239 11.728155339805824 44.80825242718446 0.9874364787035632 0.3935759881445143 5.016369659264937 4.35272817633461 1.2862817592315925 0.3680333006848349 0.0785207078555767 0.078986772223975 0.0681445056645133 0.0296866330747937 0.0025288077053784 +Lung alveolus development 2 6 1.983016958266133 0.0473655353275495 1.0995145631067962 3.45873786407767 0.5304860100832821 0.4466007586438214 0.9889190712083402 1.3350198570296243 1.0722817760600862 0.3140566665818316 0.5429445681473749 0.1135912525516411 0.2166826538338764 0.4573561220916043 0.345186345277882 +Protein processing 19 46 1.981594602876556 0.0475246317250253 12.08252427184466 45.980582524271846 0.9011703887478908 0.3916089016010577 4.43430858840224 4.931040148104543 1.176660792763282 0.3507158233798557 0.0652232672010046 1.0 0.0461562677274315 0.0511334512109197 0.0381585646670051 +Negative regulation of proteolysis 18 72 1.98089278578819 0.04760329829061 13.856796116504857 64.19174757281553 0.1536213676829086 0.6668102754358496 6.420263538974692 5.397287151567414 0.8488834550270293 0.3356070904310471 0.064756340139556 0.5468605489071586 0.7987579784661187 0.0437541692110766 0.0058023922088888 +O glycan processing 3 5 1.9782400732628025 0.0479016299649206 1.8762135922330097 5.029126213592233 0.779006640385936 0.3319918611732407 1.1540209287066336 1.1758600296433448 1.0243123329907684 0.2736840802111854 0.5283863001864543 1.0 1.0 1.0 0.3271248077551284 +Maternal placenta development 3 7 1.9658413757454412 0.0493169366842143 1.4733009708737863 4.604368932038835 0.272983125836839 0.389685533839971 0.9663090505946808 0.948314979731078 1.207690762449098 0.3027145891958461 0.0255113558567383 1.0 0.1854358412925483 0.0133829456596615 0.0171177319456962 +Cerebellar purkinje cell layer development 2 9 1.9635063594474944 0.0495873662675452 2.191747572815534 6.961165048543689 0.8392766864609098 0.2843914142715297 1.2383946131318218 1.2878998490964535 1.1730456034866912 0.2696789702944095 0.01674854618918 1.0 0.0006517968090871 0.0086586519898169 0.0541965943180989 +Regulation of defense response to virus 1 15 1.962512061854208 0.0497028977116009 3.1650485436893203 15.951456310679612 0.5849887942336425 0.4933015121782819 2.2201508187142793 1.962654437812729 0.8055377877007982 0.3010695800425433 0.4164341288949033 0.1991580424676108 0.0733374275738533 0.3051232152156647 0.6625495873916676 +Cristae formation 6 8 1.962486041772528 0.0497059241182624 4.740291262135922 8.861650485436893 0.8982766043222677 0.3392698633906088 2.216011442046921 0.6593503673812457 1.2485531022675598 0.3418736408093433 0.0081813130820843 1.0 1.0 0.2897526236095206 0.0037486095651754 +Glycosylceramide metabolic process 2 6 1.962236312913384 0.049734978047313 1.6019417475728157 3.6237864077669903 0.6319353949505291 0.2725232617281626 0.981279191145714 1.1370705133968653 1.4246462713481394 0.2720167900467778 0.0039714533726283 0.0516364610584135 0.0048484802924912 0.0276231155809849 0.0140894483762481 +Regulation of organic acid transport 5 12 1.9609297489995536 0.0498872184487571 3.0266990291262137 9.95873786407767 0.5438090247089712 0.4615742763522461 1.7589620109651245 1.3814816722984091 0.8909245759390145 0.2944812864916606 0.1789878690111356 1.0 0.2166826538338764 0.1211421538065826 0.0010313331646429 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1858629868e112180b7caa2335369b6e25c5cc17 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 6609, + "title": "Average number of proteins per term", + "value": 20.393402935391133 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..974b21b194959027fce218b285a3d456435fd7d2 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0990e8db11ba3dca452bfa9292422a3b8916e02b --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,2120 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transmembrane transport 0.559405697131542 5.6318386423345626 1.7829846262115075e-08 0.0001178305124432 0.0001178374539529 232 O60830,Q9NS69,P05023,Q99595,Q96PU5,Q9UDW1,P20674,P21796,P00846,P06576,O75964,Q8NE01,P00403,P16615,Q70HW3,Q9H2D1,P45880,Q9UBX3,Q9C0H2,Q6P4Q7,P51798,O43615,Q9Y5Y5,P50416,Q15629,P04062,Q9UHG3,Q6P4A7,O95831,Q9H0U3,O75844,Q07812,P28288,Q8WTV0,P61421,Q99808,Q9Y619,O95202,Q9HD20,P10606,Q9HC07,Q13423,O60831,P56385,O14925,Q8TB61,P05026,O96008,Q9BSK2,O43772,P52789,P12236,Q9H2V7,Q15041,Q6NUK1,P05067,Q9Y289,Q9Y277,L0R6Q1,P13073,Q02978,Q96NB2,O75298,P38435,P62258,P24539,Q9Y251,Q9H9B4,Q96QD8,Q15758,P12235,Q9Y6M7,Q8NE86,P30825,Q9Y4W6,P23786,Q15388,Q8NEW0,O14548,Q9BPX6,P27105,Q9BQT8,P53985,P31751,Q3ZCQ8,Q7L0J3,P36542,P49755,O43808,P22413,Q8IYU8,P08183,O75381,P51790,Q9UMX0,P46934,P31749,Q99442,P0DP25,Q8IXU6,Q9NWR8,P98194,Q16625,P0CG08,Q07820,Q9H936,O75915,O95747,P56134 109 +Mitochondrion organization 0.550721465611827 5.306545989912899 1.1172198285227958e-07 0.0007380980974126 0.0003691852923386 202 O60830,Q9NS69,Q99595,Q16543,P21796,Q9Y2R0,Q9UDX5,O43676,Q69YU5,Q8N4H5,P45880,P53365,Q04837,O43615,P49257,O95298,Q9Y5L4,Q9Y512,P04062,Q96A26,Q07812,O95831,Q5HYI7,Q9Y3B8,O95202,P03886,Q9NQ88,P30536,Q5T9A4,O75153,O14925,Q9NVT9,O14737,P14406,O96008,Q9BSK2,Q9Y2S7,Q6DKK2,P55786,P52789,Q9H061,Q8N183,P27544,Q9NX14,Q13505,Q9BZL1,Q5JRX3,O95168,Q86Y39,Q9Y5J9,O43464,O60220,Q9UII2,Q9BRT2,P12235,Q8N8Q8,Q8NE86,P49841,Q9Y4W6,Q10713,Q15388,O14548,Q99623,O95429,Q96CU9,Q8N2A8,Q5XKP0,Q9H3K2,Q9NX63,Q9Y6C9,Q9NUQ9,Q9UG56,P10909,Q3ZCQ8,Q8IWA4,Q9NVI7,Q9BWH2,O75438,O75306,P51572,P31749,O75880,Q9GZY8,Q9H4A6,Q9Y5J7,Q6UXV4,P0DP25,O60313,P17152,Q9BUB7,Q8N5M1,O75489,Q13501 93 +Ion transport 0.5253225327401859 5.047067587714239 4.486426738355e-07 0.0029606885879905 0.0005904062754293 219 Q15907,P05023,Q96PU5,O15173,Q9UDW1,P20674,P21796,P00846,P06576,O75964,Q8NE01,P00403,P16615,Q70HW3,Q9H2D1,P45880,Q9UBX3,Q9C0H2,Q6P4Q7,P07602,P51798,P51809,P14174,Q9UHG3,Q6P4A7,Q9H0U3,Q07812,O75844,P28288,P61421,Q99808,Q9Y619,P54105,O95202,Q9HD20,P10606,Q9HC07,P30536,Q13423,O60831,P56385,Q8TB61,P05026,O96008,O43772,P12236,Q15041,Q6NUK1,P05067,Q9Y289,Q9Y277,P13073,Q02978,Q96NB2,P62258,P24539,O76024,Q9H9B4,Q96QD8,Q15758,P12235,Q9Y6M7,Q8NE86,P30825,Q9Y4W6,Q9H0H5,Q8NEW0,O14548,Q9BPX6,P27105,Q9BQT8,P53985,P24941,Q08722,Q7L0J3,P36542,Q9NZJ7,O43808,P22413,Q96S66,Q8IYU8,P08183,P51790,Q9UMX0,P46934,P31749,P0DP25,Q9NWR8,P98194,P0CG08,Q9H936,O43681,O75915,O95747,P56134 95 +Anion transport 0.63783148015616 4.832774563199986 1.3464322769773156e-06 0.0088591017513982 0.0005904062754293 73 Q15907,Q8TB61,P21796,Q9H2D1,P12236,P45880,Q9BQT8,Q15041,Q6NUK1,Q9C0H2,Q9UBX3,Q9Y289,P07602,P51798,Q9Y277,P14174,P53985,Q02978,Q96NB2,Q9UHG3,Q08722,Q7L0J3,P0CG08,Q9H9B4,P28288,Q15758,Q96QD8,P12235,Q99808,Q9Y619,Q9NZJ7,P54105,Q9Y6M7,P30825,Q9H936,O43808,O43681,P22413,P30536,Q96S66,O75915,O60831,P08183,P51790 44 +Ion transmembrane transport 0.5283200225143582 4.825242042452651 1.3983334360206676e-06 0.009199019873552 0.0005904062754293 165 P56385,Q9UMX0,P05023,Q96PU5,Q8TB61,P05026,Q9UDW1,Q9BPX6,P21796,P20674,P46934,P00846,P06576,O43772,P27105,O75964,P00403,P16615,Q70HW3,Q9H2D1,P45880,P12236,Q9BQT8,Q15041,Q9UBX3,Q9C0H2,Q6P4Q7,P05067,Q9Y289,P51798,Q9Y277,P0DP25,P13073,Q02978,Q96NB2,P53985,Q9NWR8,P62258,P24539,P98194,Q9UHG3,Q6P4A7,Q9H0U3,Q07812,O75844,P0CG08,Q9H9B4,Q15758,P61421,P12235,P36542,Q9Y619,O95202,Q9Y6M7,Q8NE86,P30825,Q9HD20,O43808,P10606,Q9H936,Q9HC07,Q9Y4W6,P08183,O75915,Q13423,O95747,O60831,P56134,Q8IYU8,Q8NEW0,O14548,P51790 72 +Nitrogen compound transport 0.4153195957158989 4.768899389805247 1.852351362129611e-06 0.012167570601321 0.0005904062754293 623 O60830,Q15907,Q9NS69,P50897,P24390,Q14108,Q13277,Q99595,Q99584,O15173,Q16543,Q567U6,O43731,O14828,Q13445,Q8N4H5,P43307,Q9H2D1,O15260,P53365,Q9Y282,P07602,O43615,Q2M389,P49257,P51809,Q92945,O43752,Q14168,Q9Y5Y5,Q15629,P50416,Q9Y6M1,Q9Y5L4,Q9Y512,P33908,Q8TCT9,Q15363,Q07812,Q6P4A7,O95831,Q5HYI7,P13473,P51991,Q9P2W9,Q99808,Q9Y619,Q9Y5M8,Q9Y3B8,Q9C0E2,Q9HD20,P57105,P30536,O95249,O60831,O15127,Q07955,P10619,O14925,O60725,O14737,Q8TB61,Q8TD16,P05026,Q9BSK2,O96008,Q96C92,Q16850,Q5VZ89,P40616,P55786,P06493,Q96L92,O15027,O43772,Q16629,Q5T9L3,P12236,Q96KC8,Q8N183,Q9BZL1,Q15041,Q6NUK1,P51151,Q5JRX3,Q9Y289,Q9BUN8,Q9Y277,L0R6Q1,Q86U42,Q13438,P18031,O60749,P41208,Q9Y5J9,P60604,Q9BTX1,O15504,Q96NB2,O75298,P62258,Q9Y251,P61009,Q9H9B4,Q96QD8,O43464,O60220,Q15758,Q9UII2,Q9BZG1,Q9BRT2,P12235,Q12907,P51148,P61020,Q13263,Q8N8Q8,P67809,P30825,Q8NE86,O60499,P49841,Q5JRA6,Q10713,Q9P253,Q9H0U4,O95070,Q15388,O60826,Q9UBV2,Q9GZP9,Q99623,Q96D46,O95429,Q86Y82,O60784,Q9UGP8,Q969Q5,P40855,P27105,Q96ED9,Q86V81,Q07666,P84103,P41214,P20339,Q8N5M9,P50402,P09496,Q14C86,P53985,Q32P28,Q92973,Q9BVK6,P31751,P10909,Q08722,Q3ZCQ8,Q7L0J3,Q9Y5X3,Q9NR31,Q8NFH4,P49755,Q9NZJ7,O43808,Q8N1F7,P08183,O75381,Q92544,Q9BRG1,Q9Y3A6,O15498,Q13190,P46934,A6NIH7,O43768,P51572,P61019,Q9H4A5,P31749,P22626,O95721,O43633,Q9GZY8,Q9H4A6,Q99442,Q4J6C6,Q96PC5,Q9Y5J7,O15126,Q08J23,P98194,Q86YV9,P0CG08,P46379,O15400,Q07820,Q13501,Q9H936,O43681,O75915,Q9Y3E0,Q9UHB9 203 +Membrane organization 0.4860686302048383 4.653085776683129 3.270041360803333e-06 0.0213798783700078 0.0005904062754293 248 Q13277,P50897,Q9NS69,Q00765,P49069,Q16739,Q6NUK4,P16615,P45880,P51809,Q14849,O43752,Q15629,Q9Y5L4,Q9Y512,Q5J8M3,Q14696,Q15363,Q07812,O75844,Q5HYI7,O94901,Q9P2W9,O95202,Q8IXJ6,O95249,P30536,O14737,P57088,P05026,O15027,Q86XL3,P52789,Q13505,Q15041,Q9Y5J9,O43760,Q9NQC3,O60220,Q96A33,Q9BZG1,Q8N8Q8,O60499,Q5XKP0,Q9H3K2,Q9NX63,O15118,Q9NPA0,P61916,P50402,Q9BVK6,Q8N3R9,P31751,P10909,Q3ZCQ8,Q9NR31,Q8IWA4,Q15392,P49755,Q9NZJ7,Q8N1F7,P08183,P51790,O15258,Q9H6H4,O15498,Q13190,Q9H4A5,P31749,O95721,O43633,Q9H4A6,Q8NHH9,Q9Y5J7,Q6UXV4,P0DP25,O60313,P17152,P98194,Q9UQB8,P46379,O15400,O43681,Q12981 84 +Mitochondrial transport 0.6210184168396415 4.615810751408684 3.915636480833484e-06 0.0255465138532344 0.0005904062754293 84 O60830,P56385,Q9NS69,O14925,O14737,Q99595,O96008,P00846,P55786,P06576,O43772,P52789,O75964,P51572,Q8N4H5,P45880,Q9BZL1,Q9UBX3,Q6NUK1,Q9GZY8,Q5JRX3,O43615,P49257,Q14849,Q9Y5J7,Q9Y5J9,P50416,Q9Y5L4,Q9Y512,P24539,Q07812,Q3ZCQ8,O95831,O43464,O60220,Q9UII2,Q96EK5,P12235,P36542,Q8N8Q8,P49841,P30536,Q10713,P56134,P23786,Q15388 46 +Protein targeting 0.5431191253227048 4.611535027774581 3.9970628569196975e-06 0.0260707739920675 0.0005904062754293 120 O60830,Q9UHB9,Q9NS69,O14925,O60725,Q14108,O14737,Q99595,O96008,Q16543,P46934,P55786,P40855,P27105,P51572,Q8N4H5,P43307,Q9BZL1,Q15041,Q9GZY8,Q99442,Q5JRX3,O43615,P49257,Q13438,Q9Y5J7,Q9Y5J9,Q9Y5Y5,Q15629,Q9Y5L4,Q9Y512,P33908,P62258,P31751,P10909,P61009,O95831,Q3ZCQ8,O43464,O60220,P13473,P46379,Q9Y5M8,P57105,O43681,P30536,Q10713,Q15388,O75381 49 +Establishment of protein localization 0.4006036816904997 4.422173567719447 9.77129101387142e-06 0.0625377398803298 0.0006325867472938 566 O60830,Q15907,Q9NS69,P50897,P24390,Q14108,P49069,Q99595,Q13277,Q99584,Q16543,Q567U6,O43731,O14828,Q13445,Q8N4H5,P43307,O15260,P53365,Q9Y282,P11279,O43615,Q2M389,P49257,P51809,O43752,Q14168,Q9Y5Y5,Q15629,P50416,Q9Y5L4,Q9Y512,P33908,Q5J8M3,Q8TCT9,Q15363,Q07812,O95831,Q5HYI7,P13473,Q9P2W9,Q9Y5M8,Q9Y3B8,Q9C0E2,Q9HD20,P57105,P30536,O95249,O60831,O15127,P10619,O14925,O60725,O14737,Q8TD16,Q15058,P05026,O96008,Q96C92,Q16850,Q5VZ89,P40616,P55786,P06493,Q96L92,O15027,P52789,Q5T9L3,Q96KC8,Q8N183,Q9BZL1,Q15041,P51151,Q5JRX3,Q9BUN8,Q13438,P18031,O60749,P41208,Q9Y5J9,P60604,Q9BTX1,O15504,O75298,P62258,Q66GS9,Q9Y251,P61009,O43464,O60220,Q9UII2,Q96A33,Q9BZG1,Q9BRT2,Q12907,P51148,P61020,Q13263,Q8N8Q8,Q8NE86,P49841,O60499,Q5JRA6,Q10713,Q9P253,Q9H0U4,O95070,Q15388,O60826,Q8NBU5,Q9P0I2,Q9NWS0,Q9UBV2,Q9GZP9,Q99623,Q96D46,O95429,Q86Y82,O60784,Q9UGP8,Q969Q5,P40855,P27105,O15118,P20339,Q9NPA0,Q8N5M9,P50402,P09496,Q14C86,P53985,Q32P28,Q92973,Q9BVK6,P31751,P10909,Q3ZCQ8,Q9Y5X3,Q9NR31,Q8NFH4,P49755,Q8N1F7,O75381,Q92544,Q9BRG1,Q9Y3A6,O15498,Q13190,P46934,A6NIH7,O43768,P51572,P61019,Q9H4A5,P31749,O95721,O43633,Q9GZY8,Q9H4A6,Q99442,Q4J6C6,Q96PC5,Q9Y5J7,O15126,P0DP25,P98194,Q86YV9,P0CG08,P46379,O15400,Q07820,Q13501,O43681,O75915,Q9Y3E0,Q9UHB9 176 +Mitochondrial transmembrane transport 0.67566612861352 4.30787325907759 1.6483178468584825e-05 0.1032141846642296 0.0007803154504653 53 P56385,O60830,O14925,Q99595,O96008,Q9BSK2,P21796,Q9BPX6,P00846,P06576,O43772,O75964,Q9H2D1,P12236,Q9BQT8,O43615,P50416,Q96NB2,Q9NWR8,P24539,Q3ZCQ8,Q6P4A7,O95831,Q9H9B4,P12235,P36542,Q9Y619,O95202,Q8NE86,Q9H936,Q9Y4W6,P56134,Q8IYU8,Q15388 34 +Endomembrane system organization 0.4868297505746421 4.294739065974168 1.7489892261357554e-05 0.1091611292744307 0.0007803154504653 182 Q9P0I2,Q9H6H4,Q13277,P51790,Q00765,Q14108,P49069,P57088,Q9BRG1,Q9Y3A6,Q13190,Q16739,P40616,P06493,O15027,Q86XL3,Q96ED9,Q8NCM8,Q13445,Q6NUK4,P61019,Q9H4A5,P16615,Q9UL15,P31749,O95721,O43633,O15260,Q15041,Q9H4A6,O95197,Q8TBA6,Q9NPA0,Q5VU43,Q2M389,P49257,Q8NHH9,Q8N5M9,P50402,O43752,Q15629,O43760,Q9BVK6,Q5J8M3,Q8N3R9,P31751,P10909,Q15363,Q9NQC3,O75844,O94901,Q96A33,Q9UQB8,Q9P2W9,Q12907,P49755,P61020,P46379,Q9BTV4,Q13501,P16220,Q5JRA6,O43681,Q8IXJ6,Q9P253,Q8N1F7,Q12981,P20700,P27361,Q7RTS9 70 +Membrane lipid metabolic process 0.7408876024178578 4.282638799175776 1.8468985064856724e-05 0.1149070838486437 0.0008083544522757 42 P50897,O15269,Q16739,Q13510,P17900,P27544,Q9P035,P07602,P04062,Q99735,Q8NBX0,Q96G23,O43464,O95470,Q9NZJ7,Q99805,P04066,O43292,P06865,P06280 20 +Sphingolipid metabolic process 0.753753926416823 4.1267439575495155 3.6793565607151635e-05 0.2158642700882731 0.0012596544087908 33 O95470,P50897,P27544,P17900,P04062,Q9P035,O43464,Q9NZJ7,Q99805,O15269,P07602,Q96G23,Q16739,P06865,Q13510,P06280 16 +Protein localization to mitochondrion 0.6174728066786881 4.108404934279019 3.98401132730708e-05 0.231495264315018 0.0013033626389457 61 O60830,Q9NS69,O14925,O14737,Q99595,O96008,P55786,P52789,P51572,Q8N4H5,P31749,Q9Y6C9,Q9BZL1,Q9GZY8,O43615,P49257,Q9Y5J7,Q9Y5J9,P0DP25,Q9Y5L4,Q9Y512,Q07812,Q3ZCQ8,O95831,O43464,O60220,Q8N8Q8,Q10713,P30536,Q15388 30 +Establishment of protein localization to membrane 0.5130047398743014 4.078775325230461 4.527356348416056e-05 0.2586035336705745 0.0014301370464999 102 Q15907,Q13277,Q9NS69,O60725,P49069,O14737,P40855,P27105,P43307,Q9H4A5,O15118,Q15041,Q9GZY8,Q9H4A6,Q99442,Q9NPA0,Q4J6C6,Q9Y5J7,Q9Y5J9,P0DP25,Q9Y5Y5,Q15629,Q9Y5L4,Q9Y512,Q5J8M3,P98194,P31751,O60220,Q96A33,Q9BZG1,P46379,Q8N8Q8,Q9HD20,O43681,Q9UHB9 35 +Cation transport 0.475832438509953 4.077909772799655 4.544239366999214e-05 0.2594303590145436 0.0014301370464999 165 P56385,Q15907,Q9UMX0,P05023,Q96PU5,O15173,Q9UDW1,P05026,P20674,P21796,Q9BPX6,P46934,P00846,P06576,O43772,P27105,O75964,P00403,P16615,Q70HW3,P31749,Q6P4Q7,P05067,Q9Y289,P51809,P0DP25,P13073,Q96NB2,Q9NWR8,P62258,P24539,P98194,P24941,Q07812,Q9H0U3,O75844,O76024,Q9H9B4,Q96QD8,Q15758,P61421,P12235,P36542,Q99808,Q9Y619,O95202,Q9Y6M7,Q8NE86,P30825,Q9HD20,O43808,P10606,Q9H936,Q9HC07,P30536,Q9Y4W6,O95747,Q13423,P56134,Q8IYU8,Q8NEW0,O14548,P51790 63 +Regulation of t cell differentiation in thymus 0.9650784255696958 4.027121742733782 5.646380054602496e-05 0.3114585735464426 0.0016084881802098 2 P00813 1 +Nad biosynthesis via nicotinamide riboside salvage pathway 0.9496892571766796 3.9557721415972473 7.628784819946333e-05 0.3960148221765017 0.0018615710124163 2 P43490 1 +Organic anion transport 0.6586029559199464 3.951860637815288 7.754589848718574e-05 0.4010161934056683 0.001877650297946 49 Q8TB61,Q9H2D1,P12236,Q9BQT8,Q15041,Q6NUK1,Q9UBX3,Q9Y289,P07602,P14174,P53985,Q02978,Q96NB2,Q08722,Q7L0J3,Q9H9B4,Q96QD8,P28288,Q15758,Q99808,Q9Y619,Q9NZJ7,Q9Y6M7,P30825,Q9H936,O43808,O75915,O60831 28 +Microglia differentiation 0.9485054749926018 3.950257750756803 7.806707709789862e-05 0.4030759856043486 0.001877650297946 2 P04062 1 +Ion homeostasis 0.4980566129266622 3.9294633749789583 8.513564206924507e-05 0.430322809517617 0.0020204015897567 108 Q92544,P50897,Q05086,P05023,Q96PU5,P05026,Q9BPX6,P30519,P06576,P51572,Q8NE01,P16615,O75880,P09601,Q6P4Q7,P07686,P05067,Q9Y487,P0DP25,Q8N511,Q9NWR8,Q96TC7,P62258,P98194,Q93050,Q07812,Q7L0J3,Q9Y5X3,P0CG08,O75503,O76024,Q96A33,P61421,O95202,Q9Y6M7,Q8NE86,Q9HD20,Q9HC07,P30536,Q9Y4W6,P22413,Q8IYU8,Q8NEW0,P51790,O60826 45 +Keratinization 0.9437703462562892 3.928162738476014 8.559728327006688e-05 0.4320583862497926 0.0020204015897567 2 Q9Y3B8 1 +Regulation of appetite 0.9396271086120164 3.908780223714254 9.276330457641536e-05 0.4583315155736612 0.0020852812243045 2 P80303 1 +Negative regulation of response to food 0.9396271086120164 3.908780223714254 9.276330457641536e-05 0.4583315155736612 0.0020852812243045 2 P80303 1 +Regulation of response to food 0.9396271086120164 3.908780223714254 9.276330457641536e-05 0.4583315155736612 0.0020852812243045 2 P80303 1 +Cation transmembrane transport 0.4815290471437609 3.87847920067863 0.0001051115116057 0.5007850389368045 0.0022519399943505 126 P56385,Q9UMX0,P05023,Q96PU5,P05026,Q9UDW1,Q9BPX6,P21796,P20674,P46934,P00846,P06576,O43772,P27105,O75964,P00403,P16615,Q70HW3,Q6P4Q7,P05067,P0DP25,P13073,Q96NB2,Q9NWR8,P62258,P24539,P98194,Q07812,Q9H0U3,Q9H9B4,Q15758,P61421,P12235,P36542,Q9Y619,O95202,Q9Y6M7,Q8NE86,P30825,Q9HD20,Q9H936,P10606,Q9HC07,Q9Y4W6,O95747,Q13423,P56134,Q8IYU8,Q8NEW0,O14548,P51790 51 +Ornithine transport 0.93074874223143 3.867089802702555 0.0001101418769158 0.5171106570205989 0.0023256474905325 2 Q9Y619 1 +Cellular ion homeostasis 0.5284376734178893 3.857778470109688 0.0001144222821842 0.5305812868649737 0.0024020513607913 90 Q92544,P50897,Q05086,P05023,Q96PU5,P05026,Q9BPX6,P06576,P51572,P16615,O75880,P09601,P07686,P05067,Q9Y487,P0DP25,Q8N511,Q9NWR8,Q96TC7,P62258,P98194,Q93050,Q07812,Q7L0J3,P0CG08,O75503,O76024,Q96A33,P61421,O95202,Q9Y6M7,Q8NE86,Q9HD20,Q9HC07,Q9Y4W6,P22413,Q8IYU8,Q8NEW0,P51790,O60826 40 +Anion transmembrane transport 0.6743262694786711 3.8576397087049448 0.0001144872414358 0.5307827954904095 0.0024020513607913 44 Q8TB61,P21796,Q9H2D1,P12236,P45880,Q9BQT8,Q15041,Q9UBX3,Q9Y289,P51798,Q9Y277,P53985,Q02978,Q96NB2,Q9UHG3,Q9H9B4,Q15758,Q9Y619,Q9Y6M7,P30825,Q9H936,O43808,O75915,O60831,P08183,P51790 26 +Intracellular protein transport 0.4080811986532561 3.808593491348185 0.0001397595037542 0.6029666958217772 0.0027291182103435 342 O60830,Q9NS69,Q13277,Q14108,Q99595,Q16543,Q13445,Q8N4H5,P43307,O15260,P53365,Q9Y282,O43615,P49257,O43752,Q14168,Q9Y5Y5,Q15629,Q9Y5L4,Q9Y512,P33908,Q8TCT9,Q15363,Q07812,O95831,P13473,Q9P2W9,Q9Y5M8,Q9Y3B8,Q9C0E2,P57105,P30536,P10619,O14925,O60725,O14737,P05026,O96008,P40616,P55786,P06493,Q96L92,O15027,Q5T9L3,Q9BZL1,Q15041,Q5JRX3,Q9BUN8,Q13438,P18031,O60749,Q9Y5J9,P60604,O15504,O75298,P62258,P61009,O43464,O60220,Q9UII2,P51148,P61020,Q13263,Q8N8Q8,P49841,O60499,Q10713,Q9P253,Q15388,Q9UBV2,Q9GZP9,Q969Q5,P40855,P27105,P20339,P50402,P09496,Q92973,Q9BVK6,P31751,P10909,Q3ZCQ8,Q9Y5X3,Q9NR31,P49755,Q8N1F7,O75381,Q92544,Q9BRG1,Q9Y3A6,Q13190,P46934,P51572,P31749,Q9GZY8,Q99442,Q9Y5J7,P46379,O15400,Q13501,O43681,Q9UHB9 102 +Pirna metabolic process 0.9168393015685116 3.801340505832232 0.0001439153651294 0.6137247560098232 0.0027291182103435 2 Q8N2A8 1 +Intracellular transport 0.374329790427798 3.774741612576056 0.0001601735990195 0.653083826741841 0.0027795710648271 588 O60830,Q15907,Q9NS69,Q13277,P24390,Q14108,Q00765,Q99595,Q16543,Q567U6,O43731,P00846,P06576,O75964,Q13445,Q8N4H5,P43307,P16615,P45880,O15260,P53365,Q9UBX3,Q9Y282,P07602,P11279,O43615,Q2M389,P49257,P51809,Q14849,O43805,O43752,Q14168,Q9Y5Y5,Q15629,P50416,Q9Y5L4,Q9Y512,P33908,Q8TCT9,Q96JX3,Q15363,Q07812,O95831,O75844,O75503,P28288,P13473,O94901,P61421,Q9P2W9,Q9Y5M8,Q9Y3B8,Q9C0E2,P57105,P30536,O95249,P23246,P10619,P56385,O14925,O60725,Q9BWF3,O14737,Q8TD16,P05026,O96008,Q96C92,P40616,P55786,P06493,Q96L92,O15027,O43772,P52789,Q7Z4L5,Q5T9L3,Q9BZL1,Q15041,Q6NUK1,P51151,P05067,Q5JRX3,Q9BUN8,Q86U42,Q13438,P18031,O60749,Q9Y5J9,P60604,O15504,O75298,P62258,P24539,P61009,Q96D71,O43464,O60220,Q9UII2,P12235,Q12907,P51148,P61020,Q13263,Q8N8Q8,P49841,O60499,Q5JRA6,Q10713,Q9P253,Q9H0U4,P23786,O95070,Q15388,O60826,P27361,P07196,Q9UBV2,Q9GZP9,Q99623,Q96D46,O95429,Q86Y82,O60784,Q9UGP8,Q969Q5,P40855,P27105,Q96ED9,Q8NCM8,Q86V81,Q07666,P84103,P41214,O15118,P20339,P61916,P50402,P09496,Q92973,Q9BVK6,P31751,P10909,Q3ZCQ8,Q9Y5X3,Q9NR31,P36542,P49755,Q9NZJ7,Q8N1F7,O75381,Q92544,Q9BRG1,Q9Y3A6,O15498,Q13190,P46934,P51572,Q86U38,P61019,P31749,P22626,O43633,Q9GZY8,Q969X5,Q99442,Q4J6C6,Q8NHH9,Q96PC5,Q9Y5J7,O60313,Q08J23,Q96EK5,P46379,O15400,Q13501,Q9H223,O43681,P56134,Q9UHB9 180 +Protein targeting to mitochondrion 0.6479889321479619 3.72900994135255 0.0001922335689479 0.7193350827432066 0.0031369670547577 46 O60830,Q9NS69,O14925,O14737,Q99595,O96008,P55786,P51572,Q8N4H5,Q9BZL1,Q9GZY8,O43615,P49257,Q9Y5J7,Q9Y5J9,Q9Y5L4,Q9Y512,Q3ZCQ8,O95831,O43464,O60220,Q10713,P30536,Q15388 24 +Reverse cholesterol transport 0.900858242083458 3.72513248191103 0.0001952126719513 0.724808068811279 0.003154426769991 2 Q8WTV0 1 +Microglial cell proliferation 0.900858242083458 3.72513248191103 0.0001952126719513 0.724808068811279 0.003154426769991 2 P04062 1 +Localization within membrane 0.4418073373215485 3.712283972967752 0.0002053973505782 0.7427252038355217 0.0032631516585853 209 Q92544,Q15907,Q13277,Q9NS69,O60725,P49069,O14737,Q567U6,P40855,P27105,Q96L92,P43307,Q9HD45,Q9H4A5,O15118,P31749,O00264,Q15041,P35613,Q9GZY8,Q9H4A6,Q99442,Q9NPA0,P07602,Q4J6C6,Q9Y5J7,Q9BXS4,O43805,O43752,Q14168,Q9Y5J9,Q9Y5Y5,Q15629,Q9BTX1,P0DP25,Q9Y5L4,Q9Y512,Q5J8M3,P98194,Q14696,Q8N3R9,P31751,Q86YV9,Q15363,O60220,Q96A33,Q9BZG1,P46379,O15400,Q8N8Q8,Q9NZJ7,Q99805,Q13501,Q9HD20,P57105,Q9H223,O43681,O75915,Q9UHB9,O15258 60 +Lysosomal lumen acidification 0.9748371817643586 3.701896460100767 0.0002139939497158 0.7569376683263032 0.0033121452310826 3 P50897,Q8N511 2 +Inorganic ion transmembrane transport 0.4722702963515973 3.688688148122596 0.0002254133037309 0.774610318054618 0.0034172296116917 120 P56385,Q9UMX0,P05023,Q96PU5,P05026,Q9UDW1,Q9BPX6,P21796,P20674,P46934,P00846,P06576,P27105,O75964,P00403,P16615,Q9UBX3,Q6P4Q7,Q9Y289,P51798,P0DP25,P13073,Q02978,Q9NWR8,P62258,P24539,P98194,Q9UHG3,Q07812,Q9H0U3,P61421,P12235,P36542,O95202,Q9Y6M7,Q8NE86,Q9HD20,Q9H936,P10606,Q9HC07,Q9Y4W6,O95747,Q13423,P56134,Q8IYU8,O14548,P51790 47 +Proton transporting v type atpase complex assembly 0.8866528558745208 3.656781680226005 0.0002554017284555 0.8151416851025823 0.0036935449088893 2 Q8N511 1 +Vacuolar proton transporting v type atpase complex assembly 0.8866528558745208 3.656781680226005 0.0002554017284555 0.8151416851025823 0.0036935449088893 2 Q8N511 1 +Endoplasmic reticulum organization 0.6384779213641241 3.65122382149875 0.0002609936595645 0.8218505065176414 0.0037579675295471 46 Q9H6H4,Q00765,P49069,P57088,O15027,Q6NUK4,Q15041,O95197,Q9NPA0,P49257,Q8NHH9,Q8N5M9,Q15629,Q5J8M3,Q15363,Q9NQC3,Q96A33,Q9P2W9,Q12907,P46379,Q5JRA6,O43681,Q12981 23 +Ceramide metabolic process 0.7688443224333781 3.646450041429236 0.0002658881423138 0.827522483574755 0.0038035816721913 23 O95470,P27544,P17900,P04062,O43464,O15269,Q96G23,Q16739,P06865,Q13510,P06280 11 +Lytic vacuole organization 0.7656534293496463 3.6266346955701296 0.0002871390666392 0.8501281368739462 0.0040376640242952 23 Q8N511,P50897,Q14108,P04062,P11117,Q9HC07,O75503,O14773,Q9BZG1,P54802 10 +Chemical homeostasis 0.4409234122727974 3.6163100156099968 0.0002988324582968 0.8612773787715196 0.0041638088102893 188 Q92544,Q15907,P50897,Q05086,P05023,Q96PU5,Q9BPX6,P30519,Q9BWH2,O00571,Q16739,P06576,P51572,Q8NE01,P16615,P62995,P16949,O15118,P31749,Q9Y6C9,O15260,P09601,Q9P035,O75880,Q6P4Q7,P05067,O15254,P61916,Q8N5M9,Q9Y487,P0DP25,Q5BJF2,Q8N511,P53985,Q15067,P04062,Q96TC7,Q9NWR8,P98194,Q9HCL2,Q93050,Q86YV9,Q07812,Q7L0J3,Q9NQC3,Q9Y5X3,O75503,P0CG08,Q8WTV0,Q96A33,P61421,Q9Y3B8,O95202,Q9Y6M7,Q9HD20,Q9HC07,P30536,P22413,P42785,Q8IYU8,Q8NEW0,P51790 62 +Positive regulation of glycogen metabolic process 0.8768866528558753 3.609451137931989 0.00030684556345 0.8684349042397417 0.0041638088102893 2 P31751 1 +Regulation of i kappab phosphorylation 0.8768866528558754 3.609451137931989 0.00030684556345 0.8684349042397417 0.0041638088102893 2 Q96HY6 1 +Negative regulation of fatty acid transport 0.8768866528558753 3.609451137931989 0.00030684556345 0.8684349042397417 0.0041638088102893 2 P31751 1 +Mammary gland epithelial cell differentiation 0.8768866528558753 3.609451137931989 0.00030684556345 0.8684349042397417 0.0041638088102893 2 P31751 1 +Positive regulation of i kappab phosphorylation 0.8768866528558754 3.609451137931989 0.00030684556345 0.8684349042397417 0.0041638088102893 2 Q96HY6 1 +Melanocyte differentiation 0.863273157738977 3.5430058685830192 0.0003955938989463 0.9268320174636332 0.005008582525166 2 P22413 1 +Positive regulation of receptor signaling pathway via stat 0.8626812666469381 3.5401044087037965 0.0003999687636395 0.9289180851946052 0.0050159270567246 2 Q9NX40 1 +Membrane lipid biosynthetic process 0.7298845529842454 3.531417420306977 0.0004133389026468 0.9349319435090108 0.0051060874908278 26 O95470,P27544,P04062,Q9P035,Q8NBX0,O15269,Q96G23,Q16739,O43292,Q13510 10 +Camera type eye photoreceptor cell differentiation 0.8576501923646073 3.5153994547440734 0.0004390929908624 0.9451198125285634 0.005285911797106 2 P54802 1 +Retinal rod cell development 0.8576501923646073 3.5153994547440734 0.0004390929908624 0.9451198125285634 0.005285911797106 2 P54802 1 +Retinal rod cell differentiation 0.8576501923646073 3.5153994547440734 0.0004390929908624 0.9451198125285634 0.005285911797106 2 P54802 1 +Photoreceptor cell maintenance 0.857650192364606 3.515399454743939 0.0004390929908626 0.945119812528644 0.005285911797106 2 P51790 1 +Regulation of steroid hormone biosynthetic process 0.8472920982539227 3.4642948461773257 0.000531623468766 0.9702353480468424 0.0060369407303686 2 P16435 1 +Regulation of hormone biosynthetic process 0.8472920982539227 3.4642948461773257 0.000531623468766 0.9702353480468424 0.0060369407303686 2 P16435 1 +Carboxylic acid transport 0.6463203958653526 3.462094264190057 0.0005359893923091 0.9710823621901316 0.0060656744756355 38 Q9H2D1,Q9BQT8,Q15041,Q9UBX3,Q9Y289,P07602,P14174,P53985,Q02978,Q96NB2,Q7L0J3,Q9H9B4,Q96QD8,P28288,Q9Y619,Q9NZJ7,P30825,Q9H936,O75915,O60831 20 +Nephric duct development 0.8446285883397469 3.45110069244394 0.0005583052316147 0.9750497063563194 0.0062328366144284 2 O95747 1 +Nephric duct morphogenesis 0.8446285883397469 3.45110069244394 0.0005583052316147 0.9750497063563194 0.0062328366144284 2 O95747 1 +Negative regulation of synapse organization 0.844628588339748 3.45110069244394 0.0005583052316147 0.9750497063563194 0.0062328366144284 2 O00264 1 +Branching morphogenesis of a nerve 0.8446285883397471 3.45110069244394 0.0005583052316147 0.9750497063563194 0.0062328366144284 2 Q9NQC3 1 +Protein transmembrane transport 0.7031487743627076 3.4496218106525554 0.0005613724000212 0.9755506575814488 0.0062545639526195 28 O60830,Q9Y5Y5,Q9NS69,O14925,Q15629,P49755,Q99595,O75298,Q99442,P31751,Q3ZCQ8,O95831,Q15388,O75381 14 +Oxidative phosphorylation 0.5334772975856682 3.446898512124944 0.0005670615568984 0.9764533759797616 0.006286338370859 65 P56385,P14406,Q9UDW1,Q9BSK2,P20674,P00846,O75438,P06493,P06576,O43676,O75306,O75964,Q9H3K2,P00403,O95168,O75208,O95298,P13073,P14927,P24539,O14949,Q9BRT2,P36542,P09622,O75489,P03886,P22695,P15954,P10606,P56134,O14548 31 +Hydrogen peroxide biosynthetic process 0.9182466351305504 3.446521426032782 0.000567853534181 0.9765763708228558 0.006286338370859 3 P00403 1 +Golgi vesicle transport 0.434852695781791 3.423295197633876 0.0006186685171418 0.9832615289211648 0.0066730744318327 142 Q9Y3A6,P24390,O15498,Q13190,Q567U6,O43731,O14828,Q13445,P51572,P61019,Q9H4A5,O15260,Q9H4A6,Q969X5,Q9Y282,Q8TBA6,P11279,P49257,Q4J6C6,Q8NHH9,O60749,Q96PC5,O43752,O15126,Q9BVK6,P98194,Q15363,Q9NR31,Q9BZG1,Q9P2W9,P49755,O60499,O95249,Q12981,O95070,O15127,O15258 37 +Calcium ion import into sarcoplasmic reticulum 0.8390056229653766 3.4231746095188456 0.0006189430514016 0.983291890387224 0.0066730744318327 2 O75844 1 +Autophagosome membrane docking 0.839005622965376 3.4231746095188456 0.0006189430514016 0.983291890387224 0.0066730744318327 2 O95721 1 +Negative regulation of receptor binding 0.8390056229653757 3.4231746095188456 0.0006189430514016 0.983291890387224 0.0066730744318327 2 P10586 1 +Regulation of chaperone mediated autophagy 0.9125725324784768 3.420462681379031 0.0006251471222149 0.9839635223298634 0.0067289858806492 3 P10619 1 +Negative regulation of natural killer cell mediated immunity 0.8372299496892588 3.4143355224980856 0.000639377848987 0.9854038819554528 0.0068155616192828 2 P01889 1 +Protection from natural killer cell mediated cytotoxicity 0.8372299496892588 3.4143355224980856 0.000639377848987 0.9854038819554528 0.0068155616192828 2 P01889 1 +Detection of other organism 0.8372299496892588 3.4143355224980856 0.000639377848987 0.9854038819554528 0.0068155616192828 2 P01889 1 +Pyridine nucleotide biosynthetic process 0.9101371040638488 3.4092517636741126 0.0006514133219195 0.9865206107594288 0.0069022340734431 3 P43490 1 +Endoplasmic reticulum to golgi vesicle mediated transport 0.5211323889926046 3.4002894987265235 0.0006731454306121 0.9883251249053636 0.0069066197699512 67 Q9Y3A6,P24390,O15498,Q13190,O43731,P51572,Q13445,P61019,Q969X5,Q9Y282,P49257,Q8NHH9,Q96PC5,Q9BVK6,Q15363,Q9NR31,Q9P2W9,P49755,O95249,O95070 20 +Lipid localization 0.4987280282460567 3.397198751560751 0.0006807950062561 0.988901068844198 0.0069066197699512 87 Q14108,Q16739,P17900,Q99720,Q9H6V9,O15118,P31749,Q9H2V7,O15260,P07602,P61916,Q9BQE5,Q14849,P14174,Q14534,P04062,P31751,Q96JX3,P10909,Q8WTV0,Q9NZJ7,O43808,P30536,P22413,P08183 25 +Sphingolipid biosynthetic process 0.767768017128075 3.3851623456531588 0.0007113616834368 0.99093253324684 0.0071125406442274 19 O95470,P27544,P04062,Q9P035,O15269,Q96G23,Q16739,Q13510 8 +Vesicle mediated transport 0.3652992837156082 3.380113038799956 0.0007245602353214 0.991690486826064 0.0072134655059588 390 Q15907,Q13277,P50897,P24390,Q14108,P49069,Q05086,Q99584,Q96PU5,Q567U6,O43731,O14828,Q13445,P16615,O15260,P09601,Q9Y282,Q8TBA6,P11279,Q2M389,P49257,O95772,Q14849,O43752,Q5VW38,Q15363,O75503,Q8WTV0,Q9P2W9,P57105,O95249,Q9NZQ3,O15127,Q96L92,O95197,P05067,O60749,O43760,Q96D71,Q9BZG1,P61020,O60499,O95070,Q92905,Q9NX40,O15118,P20339,Q9UBG0,Q8N5M9,P09496,Q14C86,Q9BVK6,P31751,P10909,Q08722,Q7L0J3,Q9Y5X3,Q9NR31,P49755,P22413,P51790,O15258,Q92544,Q9BRG1,Q9Y3A6,P61978,O15498,Q13190,P46934,P51572,P61019,Q9H4A5,O95721,O43633,Q9H4A6,Q969X5,Q4J6C6,Q8NHH9,Q96PC5,O15126,P0DP25,P98194,O15400,Q13501,Q9H223,Q12981,Q9Y3E0 87 +Organic acid transmembrane transport 0.6394206496688513 3.379000090841408 0.0007274998411197 0.991850479804392 0.0072134655059588 36 O43772,P31749,Q9H2D1,Q9BQT8,Q15041,Q9UBX3,Q9Y289,P50416,P53985,Q02978,Q96NB2,P31751,Q9H9B4,Q96QD8,P28288,Q15758,Q9Y619,P30825,Q9H936,O75915,O60831,P08183 22 +Liposaccharide metabolic process 0.73841915704094 3.37880945916952 0.0007280044624715 0.9918776332575516 0.0072134655059588 21 O60762,P04062,Q99805,Q16880,Q9Y2B2,P16278,Q8NBX0,P04066,Q07812,O43292,Q16739,P06865,P17900,P06280 14 +Glycoprotein metabolic process 0.5067783114601022 3.3780345690505693 0.0007300590240728 0.9919872575691026 0.0072229941468526 70 O60762,Q8TCJ2,Q9NX62,Q9BS26,P35610,Q9H9S5,Q9BT22,Q9NQX7,Q96AA3,O15118,Q8WVQ1,Q9H4A6,O43505,O60476,Q9BXS4,Q9Y287,Q10472,P33908,Q9Y251,Q8NCH0,O14734,Q7LGA3,Q9Y2G5,Q9H0U3,P46977,Q86YN1,Q92542,Q99805,O60502,Q9HC07,Q9H0U4,P04843 32 +Positive regulation of fatty acid oxidation 0.8295353654927511 3.375919319575325 0.0007356948966523 0.9922804329670024 0.0072354279344874 2 P31751 1 +Positive regulation of fatty acid beta oxidation 0.8295353654927511 3.375919319575325 0.0007356948966523 0.9922804329670024 0.0072354279344874 2 P31751 1 +Mitochondrial membrane organization 0.595458424805768 3.3723568834722712 0.0007452780822549 0.9927545327145536 0.0073187858033035 48 Q9NS69,O14737,P52789,Q5XKP0,Q9H3K2,Q9NX63,P45880,Q13505,Q9Y5J7,Q6UXV4,Q9Y5J9,P0DP25,O60313,Q9Y5L4,Q9Y512,P17152,Q07812,Q3ZCQ8,Q5HYI7,Q8IWA4,O60220,Q9UII2,P12235,Q8N8Q8,O95202,P49841 26 +L methionine salvage from methylthioadenosine 0.8256880733944971 3.356641647889827 0.0007889529629521 0.99457234495478 0.0076342461671311 2 Q9BV57 1 +Amino acid salvage 0.8256880733944971 3.356641647889827 0.0007889529629521 0.99457234495478 0.0076342461671311 2 Q9BV57 1 +Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c 0.8245042912104192 3.350700672962252 0.0008060738146637 0.995153459419997 0.0077658044331094 2 Q9NR28 1 +Magnesium ion transport 0.82391240011838 3.3477285254459384 0.0008147678155301 0.9954242989919768 0.007781503602368 2 Q6P4Q7 1 +Mitochondrial respiratory chain complex assembly 0.6110342338061767 3.3470504782178745 0.0008167633612321 0.995484298328863 0.0077893059947811 44 O43674,Q96CU9,Q9BSK2,Q6DKK2,Q9Y2R0,O75438,O43676,Q69YU5,O75306,Q9H061,O75880,Q8N183,Q9NX14,O95168,Q86Y39,O95298,Q9Y6M9,Q15070,Q9Y512,O95831,Q9BRT2,P56556,O75489,Q8N8Q8,P03886 25 +Glycoprotein biosynthetic process 0.537006434391919 3.3328485916123216 0.0008596170889234 0.9965988870860104 0.0080698996316692 61 O60762,Q8TCJ2,Q9H9S5,Q9BT22,Q9NQX7,O15118,Q8WVQ1,Q9H4A6,O43505,O60476,Q9BXS4,Q9Y287,Q10472,P33908,Q8NCH0,O14734,Q7LGA3,Q9Y2G5,Q9H0U3,P46977,Q86YN1,Q92542,Q99805,O60502,Q9HC07,P04843 26 +Pyrimidine containing compound transmembrane transport 0.8194732169280875 3.3254020462039673 0.0008829111805341 0.9970845685894892 0.008172492986205 2 Q9BSK2 1 +Monovalent inorganic cation homeostasis 0.6753959721123384 3.3167003881021975 0.0009108724010511 0.9975768794120048 0.0083139358935835 29 Q92544,P50897,Q05086,P05023,Q8N511,Q96PU5,Q9Y6M7,P61421,Q93050,Q9HC07,Q9Y5X3,P0CG08,P06576,O75503,P51790,Q9Y487 16 +Metal ion homeostasis 0.4970421193066879 3.3158086293115496 0.0009137837970105 0.9976230997514174 0.0083184533256788 81 P05023,Q96PU5,P05026,Q9BPX6,P30519,P51572,Q8NE01,P16615,O75880,P09601,Q6P4Q7,P07686,P05067,Q9Y487,P0DP25,Q8N511,Q9NWR8,Q96TC7,P62258,P98194,Q07812,Q7L0J3,Q9Y5X3,O76024,Q96A33,P61421,O95202,Q8NE86,Q9HD20,Q9HC07,Q9Y4W6,Q8IYU8,Q8NEW0 33 +Positive regulation of meiotic cell cycle 0.8150340337377942 3.30301288390428 0.000956519929975 0.9982084346319032 0.0086716601059053 2 Q9H6S0 1 +Notch receptor processing 0.8138502515537163 3.2970318074088905 0.0009771243474812 0.9984367243965429 0.0087742049082925 2 Q92542 1 +Cellular monovalent inorganic cation homeostasis 0.6877577720749158 3.2962256931371683 0.0009799325760015 0.9984654984510056 0.0087874822181744 27 Q92544,P50897,Q05086,P05023,Q8N511,Q96PU5,Q9Y6M7,P61421,Q93050,Q9HC07,P0CG08,O75503,P06576,P51790,Q9Y487 15 +Organic acid transport 0.5664128698009515 3.295630304222277 0.0009820115051679 0.998486458195429 0.0087941924629473 52 O43772,P31749,Q9H2D1,Q9BQT8,Q15041,Q9UBX3,Q9Y289,P14174,P50416,P53985,Q02978,Q96NB2,P31751,Q6P4A7,Q7L0J3,Q9H9B4,Q96QD8,P28288,Q15758,Q9Y619,P30825,Q9H936,O43808,O75915,O60831,P08183 26 +Intracellular protein transmembrane transport 0.7041868579214102 3.2753696753042725 0.0010552378962973 0.9990676007892868 0.0092323157245577 24 O60830,Q9Y5Y5,Q15629,O14925,Q99595,O75298,P31751,Q3ZCQ8,O95831,Q15388,O75381 11 +Tetrapyrrole catabolic process 0.9536139768240024 3.2724732811320387 0.0010661094864117 0.99913231006691 0.0092323157245577 4 P30519 1 +Regulation of cell maturation 0.8085232317253647 3.2700612933401416 0.0010752418328356 0.9991831838305364 0.0092323157245577 2 Q8IXJ6 1 +Regulation of ph 0.7153131353611614 3.2696594137592574 0.0010767704566156 0.9991914031141164 0.0092323157245577 22 Q92544,P50897,Q05086,Q8N511,Q9Y6M7,Q93050,Q9HC07,P0CG08,O75503,P06576,P51790,Q9Y487 12 +Regulation of cellular ph 0.7153131353611614 3.2696594137592574 0.0010767704566156 0.9991914031141164 0.0092323157245577 22 Q92544,P50897,Q05086,Q8N511,Q9Y6M7,Q93050,Q9HC07,P0CG08,O75503,P06576,P51790,Q9Y487 12 +Establishment or maintenance of transmembrane electrochemical gradient 0.8079313406333255 3.267058928959882 0.0010867105727778 0.9992428698728282 0.0092791604334482 2 Q07812 1 +Keratan sulfate metabolic process 0.8792184724689169 3.265544141084466 0.0010925397589927 0.999271514281268 0.0093168971189455 3 P15586,O43505 2 +Pyramidal neuron differentiation 0.8758009544334966 3.249500256921974 0.0011560797379399 0.999521546210996 0.0096961053147782 3 P04062 1 +Amino acid betaine transport 0.8037881029890523 3.246010653097827 0.0011703445988673 0.9995646399567352 0.0097629965105601 2 Q96QD8 1 +Quaternary ammonium group transport 0.8037881029890523 3.246010653097827 0.0011703445988673 0.9995646399567352 0.0097629965105601 2 Q96QD8 1 +Phosphatidylinositol acyl chain remodeling 0.802012429712935 3.236972920017741 0.0012080487485275 0.999660766057774 0.0099799927237731 2 Q96N66 1 +Eating behavior 0.8008286475288569 3.230942066118492 0.0012338294533236 0.9997139699135076 0.0100299862939923 2 P50416 1 +Cerebellar purkinje cell layer formation 0.800828647528858 3.230942066118492 0.0012338294533236 0.9997139699135076 0.0100299862939923 2 P04062 1 +Forebrain regionalization 0.8008286475288569 3.230942066118492 0.0012338294533236 0.9997139699135076 0.0100299862939923 2 P62995 1 +Negative regulation of insulin secretion involved in cellular response to glucose stimulus 0.7999408108907986 3.2264159290369285 0.0012535105136863 0.9997488970770606 0.010146996570148 2 Q8N5M9 1 +Decidualization 0.8698643264473378 3.2215534500495933 0.0012749767850446 0.999782148697116 0.0102634854718147 3 P07858 1 +C21 steroid hormone biosynthetic process 0.866165459777845 3.204091469375577 0.0013548942382204 0.9998716266448788 0.0107626154091332 3 Q14849 1 +Vacuole organization 0.5563406738475609 3.202559767113099 0.0013621203205791 0.9998776212541424 0.0108070266491087 52 P50897,Q9UMX0,Q14108,Q86Y82,Q96ED9,P16615,P53365,Q8TBX8,P20339,P11117,P07686,P54802,Q8N511,P04062,O75503,O14773,Q9BZG1,P10253,Q9HC07,Q9P253,Q9H0U4 21 +Actin myosin filament sliding 0.7949097366084663 3.2007191540795987 0.0013708507652179 0.99988449171627 0.0108594750164567 2 P09493 1 +Manganese ion transport 0.8644168146832337 3.1958230050708987 0.0013943261678128 0.9999011129284018 0.0108796949741148 3 Q9HC07,Q9HD20 2 +Manganese ion transmembrane transport 0.8644168146832337 3.1958230050708987 0.0013943261678128 0.9999011129284018 0.0108796949741148 3 Q9HC07,Q9HD20 2 +Negative regulation of b cell apoptotic process 0.9350647648230402 3.1913053740494384 0.0014163149710166 0.999914505675508 0.0110122654628815 4 P00813 1 +Estrogen biosynthetic process 0.7928381177863298 3.1901140009987636 0.0014221668147538 0.999917753552983 0.0110447714203384 2 Q53GQ0 1 +Axon ensheathment in central nervous system 0.8616715551108884 3.18282479048552 0.0014584583973098 0.9999353153992324 0.0112080831951404 3 P10909 1 +Alpha ketoglutarate transport 0.7907664989641932 3.1794947183594116 0.0014753205801347 0.9999421463073176 0.0112982545934075 2 Q9BQT8 1 +Protein insertion into membrane 0.6388631449790142 3.175834903027968 0.0014940595418269 0.999948894744475 0.0113758519722742 31 Q15629,Q9NS69,P46379,Q9Y5L4,Q9Y512,O14737,P49069,Q8N8Q8,Q5J8M3,Q9NPA0,O43681,Q9Y5J7,O60220,Q96A33,Q9Y5J9 15 +Regulation of calcium ion export across plasma membrane 0.7886948801420562 3.168861269061124 0.0015303742398773 0.99995981394629 0.0115856166682123 2 P0DP25 1 +Regulation of heart rate by chemical signal 0.7886948801420564 3.168861269061124 0.0015303742398773 0.99995981394629 0.0115856166682123 2 P09493 1 +Response to light intensity 0.786919206865939 3.159735580350396 0.0015791238066729 0.999970897257097 0.0118865936654912 2 P31751 1 +Lipoprotein metabolic process 0.7495137434722057 3.149991888815011 0.00163274995573 0.9999795936296456 0.0122762735579292 18 Q9NUJ1,P50897,P04062,Q16739,Q9BQE5,Q8N2K0 6 +Glutamine transport 0.7842556969517636 3.146027429945386 0.0016550448283003 0.9999823936842048 0.0122852829112665 2 Q96QD8 1 +Negative regulation of amyloid precursor protein biosynthetic process 0.8537217853251056 3.145064802269966 0.0016605004441738 0.9999830182090028 0.0122852829112665 3 Q9NQX7 1 +Positive regulation of b cell proliferation 0.9207019704603494 3.127888168433524 0.0017606715872573 0.9999912506784048 0.0125797605623608 4 P00813 1 +Negative regulation of glycogen metabolic process 0.7789286771234119 3.1185402188228 0.0018174933487771 0.999993993945306 0.0127939795202781 2 P22413 1 +Positive regulation of protein localization to cilium 0.7789286771234119 3.1185402188228 0.0018174933487771 0.999993993945306 0.0127939795202781 2 Q96C92 1 +Inner mitochondrial membrane organization 0.6918806229522827 3.1184488046099195 0.0018180572397306 0.9999940163273556 0.0127939795202781 22 O60313,Q5HYI7,Q9Y5L4,Q13505,O95202,P17152,Q9Y5J7,Q5XKP0,O60220,Q9H3K2,Q6UXV4,Q9Y5J9,Q9NX63 13 +Prostate gland growth 0.8481349911189939 3.1184215328967437 0.0018182254971379 0.9999940229896864 0.0127939795202781 3 P07602,Q9NZJ7 2 +Cellular response to manganese ion 0.7786327315773927 3.1170103697927662 0.0018269514575162 0.999994358526316 0.0128313732016202 2 P05067 1 +Negative regulation of sodium ion transmembrane transport 0.8469508584961514 3.112763029472213 0.0018534477249632 0.999995266292828 0.0129500730164421 3 O95747,P46934 2 +Negative regulation of lymphocyte migration 0.777744894939334 3.112419061089742 0.0018556088888743 0.9999953335482664 0.0129500730164421 2 P31749 1 +Cellular response to oxidised low density lipoprotein particle stimulus 0.777744894939334 3.112419061089742 0.0018556088888743 0.9999953335482664 0.0129500730164421 2 P31749 1 +Walking behavior 0.9153094462540696 3.1039482798690905 0.0019095670899855 0.9999967354673402 0.0132570231920967 4 O43464,O75844,Q8N2K0 3 +Cellular macromolecule localization 0.3481965804135069 3.103350151310174 0.0019134310604078 0.9999968179338192 0.0132695339750635 597 O60830,Q15907,Q9NS69,Q13277,P24390,Q14108,P49069,Q99595,Q96PU5,Q16543,O43731,O00571,Q13445,Q8N4H5,P43307,O00264,O15260,P53365,Q9Y282,P11279,O43615,P49257,Q9BXS4,O43805,O43752,Q14168,Q9Y5Y5,Q15629,Q9Y5L4,Q9Y512,P33908,Q5J8M3,Q8TCT9,Q16880,Q14696,Q15363,Q07812,O95831,O14773,P13473,O94901,Q9P2W9,Q9Y5M8,Q9Y3B8,Q9C0E2,Q9HD20,P57105,P30536,P10619,O14925,O60725,O14737,Q8TD16,P05026,O96008,Q96C92,Q5VZ89,P40616,P55786,P06493,Q96L92,O15027,P52789,Q9HD45,Q9BV73,Q7Z4L5,Q5T9L3,Q9BZL1,Q15041,P35613,Q5JRX3,Q9BUN8,Q13438,P18031,O60749,Q9UK61,Q9Y5J9,Q8NEY8,P60604,O75116,O15504,O75298,P62258,P61009,Q9NQC3,O43464,O60220,Q9UII2,Q96A33,Q9BZG1,P51148,P61020,Q13263,Q8N8Q8,P67809,P49841,O60499,Q5JRA6,Q10713,O43292,Q9P253,Q9H0U4,Q15388,Q8NBU5,Q9P0I2,Q9NWS0,Q9UBV2,Q9GZP9,Q99623,Q96D46,O95429,Q86Y82,Q96HY6,Q969Q5,Q9UGP8,P40855,P27105,Q8NCM8,Q7Z3C6,P41214,O15118,P33176,Q9Y6C9,P20339,Q9NPA0,Q99729,P50402,P09496,Q92973,Q9BVK6,Q8N3R9,P31751,P10909,Q3ZCQ8,Q9Y5X3,Q9NR31,P49755,Q99805,Q8N1F7,O75381,O15258,Q92544,Q9BRG1,Q9Y3A6,Q13190,P46934,P51572,Q9H4A5,P31749,Q9GZY8,Q9H4A6,Q99442,Q4J6C6,Q9Y5J7,P0DP25,P98194,Q86YV9,Q8WXW3,Q16625,Q15555,P46379,P31483,O15400,Q13501,Q9H223,O43681,O75915,Q9UHB9,Q9P2S5 169 +Mitochondrial respirasome assembly 0.7741935483870999 3.0940273507038145 0.0019745928209919 0.9999978776471312 0.0136364513625246 2 P14406 1 +Secondary alcohol metabolic process 0.5843842126198256 3.08949519822335 0.002004969474914 0.9999982643781786 0.013831777932888 43 O15118,P16435,P04062,Q15125,O75845,P05067,Q16850,P61916,O75874,P48735,Q15800,Q14849,Q9BQE5,Q8WTV0,Q15392,Q14534 16 +Positive regulation of heart rate 0.8392539964475852 3.0758849694625434 0.0020987879783522 0.9999990675647976 0.0142704627046607 3 P09493,P00813 2 +Negative regulation of protein targeting to mitochondrion 0.7703462562888457 3.074055032673328 0.0021117047458996 0.9999991440151764 0.0143141094006672 2 P49257 1 +Regulation of lysosomal lumen ph 0.965525331637407 3.070762205770527 0.002135131221397 0.9999992670352498 0.0143990635124625 5 Q8N511,P50897,O75503 3 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.8374777975133186 3.0673504806201164 0.0021596547415498 0.999999376921274 0.0145220244276507 3 P10321,P01889 2 +Detection of external biotic stimulus 0.8374777975133192 3.0673504806201164 0.0021596547415498 0.999999376921274 0.0145220244276507 3 Q8WTV0,P01889 2 +Negative regulation of amyloid beta clearance 0.7685705830127288 3.064820152316425 0.002178009257447 0.9999994482449382 0.0146136682055507 2 Q16850 1 +Protein localization to perinuclear region of cytoplasm 0.7664989641905917 3.0540326030673084 0.002257875415055 0.999999674912144 0.0149372358539528 2 Q13501 1 +Intraciliary retrograde transport 0.7662030186445723 3.052490333865077 0.0022695104033829 0.999999699025552 0.0149842100459121 2 Q7Z4L5 1 +Sphingosine biosynthetic process 0.902144657206932 3.045202520251278 0.0023252367810462 0.9999997919285188 0.0151485300569264 4 Q13510,P04062 2 +Tripartite regional subdivision 0.9012706531576916 3.0412871867562603 0.0023556902555768 0.9999998299414986 0.015293474360616 4 Q8N2A8,Q9UK61 2 +Glycerol 3 phosphate metabolic process 0.7638354542764161 3.0401414433241363 0.0023646706725657 0.9999998397635532 0.0153367109666211 2 Q9HCL2 1 +Membrane lipid catabolic process 0.825141806416402 3.0398191729337785 0.0023672022926843 0.9999998424284944 0.0153380783846579 13 O95470,P50897,P04062,P17900,P04066,P06865,Q13510,P06280 8 +Semaphorin plexin signaling pathway involved in neuron projection guidance 0.8310584661900374 3.0364301136088754 0.0023939759800004 0.9999998680385525 0.0154058298459815 3 P42892 1 +Regulation of histamine secretion by mast cell 0.7593962710861233 3.0169356805394956 0.0025534398547335 0.9999999541213638 0.0161843727380918 2 P51809 1 +Macroautophagy 0.4295317368075487 3.012765561335489 0.0025887882245545 0.9999999637013705 0.0163882197088898 107 Q99623,Q9BRG1,Q9UMX0,Q5T8D3,Q16543,P21796,Q9Y2S7,Q86Y82,O15269,P46934,Q96HY6,Q7Z3C6,P16615,O15118,P31749,O95721,O43633,P27544,P53365,P09601,Q8TBX8,Q15382,P20339,P51809,Q9Y6I9,Q9Y487,P04062,Q93050,Q9Y5X3,O43464,P13473,P61421,P12235,Q13501,O14681,Q9NQ88,Q9Y263,Q9H0U4,P27361 39 +Neurofilament cytoskeleton organization 0.7585084344480646 3.0122864280002135 0.0025928781682793 0.9999999646718768 0.0163984036499122 2 P07196 1 +Steroid metabolic process 0.4739601564405607 3.011001267586586 0.0026038776559331 0.9999999671551704 0.0164365113926096 70 P05023,Q15125,Q16850,Q13510,O15118,P16435,Q14739,Q99538,P05067,P61916,Q9BQE5,Q15800,Q14849,Q14534,P04062,P38435,O14734,Q8WTV0,Q15392,Q53GQ0,O95470,O75845,P30536 23 +Epithelial cell differentiation involved in prostate gland development 0.8238653900365953 3.001640534724479 0.002685290591722 0.9999999808498694 0.0168698531565505 3 P07602 1 +Lymphocyte anergy 0.7561408700799084 2.999875181416238 0.0027009026245079 0.9999999827320708 0.0169196828866095 2 P01889 1 +Positive regulation of receptor catabolic process 0.7561408700799084 2.999875181416238 0.0027009026245079 0.9999999827320708 0.0169196828866095 2 P18031 1 +T cell tolerance induction 0.7561408700799084 2.999875181416238 0.0027009026245079 0.9999999827320708 0.0169196828866095 2 P01889 1 +Phosphatidylcholine acyl chain remodeling 0.7546611423498109 2.9921083548600893 0.0027705790682743 0.9999999891181516 0.0172906110124885 2 Q96N66 1 +Phosphatidylethanolamine biosynthetic process 0.819419775014784 2.980063480561365 0.0028818865444875 0.9999999947962472 0.0177175703930399 3 Q9HBU6,Q9UG56 2 +Response to interleukin 12 0.7522935779816546 2.9796657187232816 0.0028856309602967 0.9999999949238066 0.0177184974800553 2 Q08722 1 +Inorganic anion transport 0.6406255835232011 2.967960251415298 0.0029978309491802 0.9999999975870644 0.0182269224867823 27 P45880,P54105,Q9Y6M7,Q9UBX3,Q9C0H2,P21796,Q9Y289,P51798,Q9Y277,Q9UHG3,O43681,P0CG08,P22413,P30536,Q96S66,P08183,P51790 17 +Definitive erythrocyte differentiation 0.7499260136134984 2.967203696466468 0.0030052178820707 0.9999999977023728 0.0182382782209418 2 O43251 1 +Negative regulation of cell volume 0.7493341225214594 2.9640851556499395 0.0030358426429115 0.99999999812452 0.0183492604003338 2 P51790 1 +Plasma membrane phospholipid scrambling 0.7493341225214591 2.9640851556499395 0.0030358426429115 0.99999999812452 0.0183492604003338 2 Q7Z3C6 1 +Mitochondrion endoplasmic reticulum membrane tethering 0.748150340337381 2.957844425975539 0.003097984351243 0.999999998757772 0.018664155494408 2 P16615 1 +Regulation of mitochondrion organization 0.5477062119740405 2.9488726530507785 0.0031893536754972 0.9999999993221692 0.0191307755220915 48 O14737,P21796,Q8N2A8,Q9H3K2,P31749,P27544,Q9Y6C9,Q9GZY8,Q9H4A6,Q9NUQ9,O60313,Q9UG56,Q96A26,P10909,Q07812,O43464,Q9UII2,P12235,Q13501,Q8NE86,Q9NQ88,P30536 22 +Golgi organization 0.505475175271876 2.947853164780572 0.0031998901515164 0.9999999993679054 0.019152666672765 59 Q9Y3A6,Q13190,P40616,P06493,O15027,Q13445,P61019,Q9H4A5,Q9UL15,O15260,Q9H4A6,Q8TBA6,Q5VU43,P49257,Q8NHH9,O43752,Q9BVK6,Q15363,Q9P2W9,Q12907,P49755,P27361,Q7RTS9 23 +Bone growth 0.8112748531159937 2.9403805838391026 0.0032780933172105 0.9999999996236518 0.0195179448049047 3 O75844 1 +Growth plate cartilage development 0.8112748531159937 2.9403805838391026 0.0032780933172105 0.9999999996236518 0.0195179448049047 3 O75844 1 +Glucosylceramide metabolic process 0.8776667988819216 2.93482108624854 0.0033374006029933 0.9999999997460208 0.0198531778444493 4 Q16739 1 +Glycosylceramide biosynthetic process 0.8094316457272143 2.9313730354067284 0.0033746727980039 0.9999999998016386 0.0200129305763298 3 Q16739 1 +Hypotonic response 0.8089781504750122 2.929155307448971 0.0033988455162785 0.9999999998310184 0.0200562232295401 3 P30536 1 +Cellular hypotonic response 0.8089781504750122 2.929155307448971 0.0033988455162785 0.9999999998310184 0.0200562232295401 3 P30536 1 +Mitochondrial protein catabolic process 0.7416395383249514 2.923433195990935 0.0034619450319559 0.9999999998888 0.0202836832590398 2 Q9UG56 1 +Protein exit from endoplasmic reticulum 0.6512482972548609 2.9205551752583743 0.0034940831990457 0.999999999910146 0.0203778768113008 24 Q92544,Q9UBV2,Q9GZP9,O15260,Q9BVK6,Q8TCT9,Q9BUN8,Q13438,P49257,O15027,Q9NR31,P51572 12 +Regulation of l glutamate import across plasma membrane 0.8052266663452201 2.9107859392463524 0.0036052091911185 0.9999999999570026 0.0207731713549278 3 Q15041 1 +Regulation of amino acid transmembrane transport 0.8052266663452201 2.9107859392463524 0.0036052091911185 0.9999999999570026 0.0207731713549278 3 Q15041 1 +L glutamate import across plasma membrane 0.8052266663452201 2.9107859392463524 0.0036052091911185 0.9999999999570026 0.0207731713549278 3 Q15041 1 +Magnesium ion homeostasis 0.804362416279972 2.9065481377840436 0.0036544066586914 0.9999999999689744 0.0209470716455261 3 Q8NE01 1 +Transepithelial chloride transport 0.7383841373187366 2.906172005667676 0.0036588026133093 0.999999999969866 0.0209540957290825 2 P51798 1 +Regulation of autophagy 0.4236132496672732 2.9057081139514325 0.0036642308592649 0.999999999970932 0.0209670145011964 99 P10619,Q9UMX0,P21796,Q9Y2S7,O15269,P46934,O15118,P31749,P27544,P09601,Q8TBX8,P07602,Q9BXS4,Q86UE4,Q9Y487,P04062,Q93050,Q9Y5X3,O75844,O43464,P61421,Q9NZ45,Q9NZJ7,Q07820,Q9NQ88,Q8IXJ6,P30536,Q05639 28 +Process utilizing autophagic mechanism 0.3994056315566824 2.900097145543228 0.0037304702396727 0.999999999981268 0.0212907407720184 168 P10619,Q99623,Q9BRG1,Q9UMX0,Q5T8D3,Q16543,P21796,Q9Y2S7,Q86Y82,O15269,P46934,Q9BWH2,Q96HY6,Q969Q5,O15027,P52789,P16615,O15118,P31749,O95721,O43633,P27544,P53365,P09601,Q8TBX8,Q15382,P20339,P07602,P51809,Q9BXS4,Q9Y6I9,Q86UE4,Q9Y487,P04062,Q93050,P10909,Q9Y5X3,O75844,O43464,P13473,Q9UII2,P61421,Q9NZ45,P12235,Q9NZJ7,Q07820,Q13501,P49841,O14681,Q9NQ88,Q8IXJ6,P30536,Q9P253,Q9H0U4,Q9Y263,Q05639,P20073,P27361 58 +Protein o linked glycosylation via threonine 0.7369044095886391 2.898313711294898 0.0037517511343809 0.999999999983734 0.0213752786613136 2 Q10472 1 +Positive regulation of nitric oxide synthase activity 0.868522357121702 2.893194077379234 0.0038134558045337 0.9999999999891982 0.0216894401137379 4 P31749,Q8WTV0,P00374 3 +Regulation of glucocorticoid metabolic process 0.735720627404561 2.892021529437053 0.0038277171605898 0.9999999999901732 0.021751833804246 2 P05023 1 +Regulation of cardiac muscle cell action potential involved in regulation of contraction 0.7342408996744634 2.884149358802852 0.0039247255972927 0.9999999999948372 0.0221696679252202 2 P16615 1 +Dna methylation involved in gamete generation 0.7992856201034054 2.881609228258424 0.00395650075742 0.9999999999958186 0.0223110183496493 3 Q8N2A8 1 +Ceramide biosynthetic process 0.7935411776616212 2.8751455866444005 0.0040384124079932 0.9999999999975718 0.0226954656500235 13 P27544,P04062,Q96G23,Q16739,Q13510 5 +Protein depalmitoylation 0.863762604900286 2.871441769123184 0.0040860405518625 0.99999999999823 0.022904700599881 4 Q9NUJ1,P50897 2 +Peptidyl tyrosine autophosphorylation 0.7315773897602875 2.869959973295245 0.0041052376205006 0.9999999999984416 0.0229539047664033 2 P27361 1 +Positive regulation of phospholipase a2 activity 0.7315773897602875 2.869959973295245 0.0041052376205006 0.9999999999984416 0.0229539047664033 2 Q9Y263 1 +Regulation of protein kinase c activity 0.7315773897602875 2.869959973295245 0.0041052376205006 0.9999999999984416 0.0229539047664033 2 Q8NDZ4 1 +Sterol metabolic process 0.5721251328966378 2.869338394445866 0.0041133146835055 0.999999999998523 0.0229796253113169 38 O15118,P16435,P04062,Q15125,O75845,P05067,Q16850,P61916,Q9BQE5,Q15800,Q14849,Q8WTV0,Q15392,Q14534 14 +Positive regulation of endoplasmic reticulum unfolded protein response 0.7948490230905837 2.85975182457161 0.0042397265456797 0.9999999999993616 0.0234676321108855 3 Q07812,P57088 2 +Positive regulation of ire1 mediated unfolded protein response 0.7948490230905837 2.85975182457161 0.0042397265456797 0.9999999999993616 0.0234676321108855 3 Q07812,P57088 2 +Glycosylceramide catabolic process 0.7926362823436237 2.84882832994413 0.0043880550557249 0.9999999999997616 0.02408692347449 3 P04062 1 +Negative regulation of protein exit from endoplasmic reticulum 0.7924807578448883 2.8480600058709937 0.0043986630017771 0.9999999999997776 0.0241251151690831 3 Q9GZP9,Q13438 2 +Amino acid transport 0.6550976775277323 2.8428995322687296 0.0044705160187463 0.999999999999862 0.0244178846015659 21 Q96NB2,Q9Y619,Q15041,P30825,Q9H936,O75915,O75746,Q7L0J3,Q6P4A7,P55011,O60831,Q9H9B4,Q96QD8,P08195,Q15758 15 +Porphyrin containing compound metabolic process 0.6980862814585418 2.8405920941724077 0.0045029868998733 0.9999999999998888 0.0245344108996399 18 P09601,P22830,O00264,P30519 4 +Protein transmembrane import into intracellular organelle 0.7521792656285118 2.8373231458617045 0.0045493542338044 0.9999999999999184 0.0247122165294346 15 O60830,Q9Y5Y5,O14925,Q99595,Q3ZCQ8,O95831,Q15388 7 +Response to muscle activity 0.8555764889809921 2.83389356053705 0.0045984645622392 0.999999999999941 0.0249108625342942 4 Q9UDX5 1 +Diacylglycerol metabolic process 0.7879383511897677 2.825587249504334 0.004719403319894 0.9999999999999736 0.0253787929545808 3 Q9HCL2 1 +Membrane protein intracellular domain proteolysis 0.8532464312403882 2.82317413599259 0.0047550736872372 0.9999999999999792 0.0255498227633748 4 Q8TCT8,Q8TCT9 2 +Eye photoreceptor cell development 0.7871521610420162 2.821691359991557 0.0047771127677258 0.999999999999982 0.0255643224954657 3 Q15555,P54802 2 +Eye photoreceptor cell differentiation 0.7871521610420162 2.821691359991557 0.0047771127677258 0.999999999999982 0.0255643224954657 3 Q15555,P54802 2 +Olfactory behavior 0.7203314590115456 2.8097716402236617 0.0049576662713843 0.9999999999999946 0.026302440960489 2 O76024 1 +Chemosensory behavior 0.7203314590115456 2.8097716402236617 0.0049576662713843 0.9999999999999946 0.026302440960489 2 O76024 1 +L serine transport 0.7844878626406211 2.8084747114026047 0.00497767916857 0.9999999999999952 0.0263601615585573 3 Q9H9B4,Q96QD8 2 +Divalent inorganic cation homeostasis 0.5001392335536211 2.8081306768982217 0.0049830002077886 0.9999999999999954 0.0263661474387699 56 P05026,Q9BPX6,P51572,Q8NE01,P16615,Q6P4Q7,P07686,P05067,P0DP25,Q9NWR8,Q96TC7,P62258,P98194,Q07812,Q7L0J3,O76024,Q96A33,O95202,Q8NE86,Q9HD20,Q9HC07,Q8IYU8,Q8NEW0 23 +Negative regulation of glial cell proliferation 0.7838954399974418 2.8055329742360393 0.0050233441347653 0.9999999999999964 0.0264536106666647 3 P30536 1 +Protein localization to endoplasmic reticulum 0.5642641173152025 2.8041669834388685 0.0050446770838401 0.999999999999997 0.0264539607244414 38 Q15629,P46379,P24390,Q9Y5M8,P33908,Q99442,O43731,O43681,Q96HY6,O43292,Q9NQC3,P51572,O15258 13 +Proton transmembrane transport 0.5509473976818524 2.802822108554775 0.0050657602433501 0.9999999999999972 0.0264539607244414 43 P56385,P05023,Q9UDW1,P20674,P00846,P06576,O75964,P00403,P13073,P24539,P61421,P12235,P36542,Q9H936,P10606,P56134,Q13423,O14548,P51790 19 +Long chain fatty acid import across plasma membrane 0.7831689114142262 2.801923859602325 0.0050798861288678 0.9999999999999976 0.0264539607244414 3 P31751 1 +Regulation of long chain fatty acid import across plasma membrane 0.7831689114142262 2.801923859602325 0.0050798861288678 0.9999999999999976 0.0264539607244414 3 P31751 1 +Response to oxygen levels 0.4695063564006074 2.7994526361151952 0.0051189325687472 0.999999999999998 0.0265133427483157 66 Q92544,P00813,Q9UMX0,P05026,P30519,P00846,P55786,O75306,P31749,P09601,Q9Y487,Q8N511,Q96A26,Q9Y4P3,O95831,P61421,Q99808,Q9NQ88,Q8IXJ6,P78536 20 +Protein demannosylation 0.7825245673535537 2.7987216592036224 0.0051305342061547 0.9999999999999982 0.0265389608152524 3 P33908 1 +Negative regulation of anion transmembrane transport 0.7182598401894088 2.7986350866269087 0.0051319098081241 0.9999999999999984 0.0265389608152524 2 O75915 1 +Regulation of blood pressure 0.6901870746113522 2.7920476378729195 0.0052375644537958 0.9999999999999992 0.0269377925876551 18 P09601,P09493,Q6P179,P42892,Q9Y5X3,Q9UIQ6,P42785,Q9HB40,Q9NZ08 9 +Regulation of homophilic cell adhesion 0.7167801124593112 2.7906709819251994 0.0052598910449446 0.9999999999999992 0.0270315862488639 2 Q9H3S7 1 +Regulation of type b pancreatic cell development 0.7791592658377773 2.781976496206332 0.0054028952791547 0.9999999999999996 0.0275310215111284 3 P31749,Q15382 2 +Segment specification 0.7150044391831941 2.781103672279676 0.0054174433746156 0.9999999999999998 0.0275838854105047 2 O95747 1 +Embryonic skeletal joint morphogenesis 0.7144125480911551 2.777912048588029 0.0054709424616721 0.9999999999999998 0.027643317071247 2 O95747 1 +Canonical wnt signaling pathway involved in osteoblast differentiation 0.714412548091155 2.777912048588029 0.0054709424616721 0.9999999999999998 0.027643317071247 2 P49841 1 +Neural plate development 0.714412548091155 2.777912048588029 0.0054709424616721 0.9999999999999998 0.027643317071247 2 O14641 1 +Canonical wnt signaling pathway involved in regulation of cell proliferation 0.714412548091155 2.777912048588029 0.0054709424616721 0.9999999999999998 0.027643317071247 2 O14641 1 +Nephron tubule formation 0.7144125480911551 2.777912048588029 0.0054709424616721 0.9999999999999998 0.027643317071247 2 O95747 1 +Limb joint morphogenesis 0.7144125480911551 2.777912048588029 0.0054709424616721 0.9999999999999998 0.027643317071247 2 O95747 1 +Developmental induction 0.714412548091155 2.777912048588029 0.0054709424616721 0.9999999999999998 0.027643317071247 2 Q96C57 1 +Mesenchymal stem cell differentiation 0.714412548091155 2.777912048588029 0.0054709424616721 0.9999999999999998 0.027643317071247 2 P49841 1 +Embryonic skeletal joint development 0.7144125480911551 2.777912048588029 0.0054709424616721 0.9999999999999998 0.027643317071247 2 O95747 1 +Sulfate transport 0.7761989342806174 2.767217740138417 0.0056536980038937 1.0 0.0283364617074396 3 Q9UBX3,Q02978 2 +Carbohydrate derivative transport 0.7220209615899481 2.7656523009273535 0.0056809070548835 1.0 0.0283364617074396 16 Q96AA3,Q99808,P12236,Q8TB61,Q9NZJ7,Q6NUK1,O43808,P07602,P61916,L0R6Q1,Q08722,Q8WTV0 12 +Positive regulation of blood circulation 0.8395025170269413 2.759655860716842 0.0057862278698552 1.0 0.0284321040831773 4 P09493,P00813,P05023 3 +Granzyme mediated programmed cell death signaling pathway 0.7090855282628035 2.7491305850080727 0.0059753575449013 1.0 0.0290757607703326 2 P11279 1 +Cytoplasm organization 0.7715413003041046 2.7439426001610747 0.0060706151622578 1.0 0.0294256791688798 3 Q8N2A8 1 +Motor learning 0.7079017460787255 2.7427207763529062 0.006093247383816 1.0 0.0295020307396629 2 Q05086 1 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.588399604230047 2.7368367952660826 0.0062033059895052 1.0 0.0299690418747369 30 Q9H4A5,Q9P2W9,P49755,P24390,Q9H4A6,Q969X5,Q9Y282,O43731,O15258 9 +Regulation of presynaptic cytosolic calcium ion concentration 0.7046463450725107 2.725067608880245 0.0064288321190135 1.0 0.0307879659150041 2 Q00535 1 +Sphingoid metabolic process 0.8845727757261481 2.7214117134188545 0.0065003746014249 1.0 0.0310547738745326 5 Q13510,P04062 2 +Metal ion transport 0.4080693040391125 2.718500250126431 0.0065578606174783 1.0 0.0312029523548698 109 Q15907,Q13642,Q99996,P05023,Q9UMX0,Q96PU5,O15173,P05026,Q9BPX6,P21796,P46934,P27105,P16615,P33176,P31749,Q6P4Q7,Q9Y289,P54709,P0DP25,Q9NWR8,P62258,P98194,P24941,Q4KMQ2,Q07812,Q9H0U3,O43865,O75844,O76024,Q9H9B4,Q96QD8,O95202,Q9Y6M7,Q8NE86,Q9HD20,Q9HC07,P30536,Q9Y4W6,O95747,P55011,Q8IYU8,Q8NEW0 42 +Response to corticosterone 0.7657312912926986 2.714815085217219 0.0066312785612323 1.0 0.0314842816172303 3 P07196 1 +Female genitalia development 0.7025747262503741 2.7138137331769783 0.0066513553420362 1.0 0.031534295161777 2 Q07812 1 +Vagina development 0.7025747262503741 2.7138137331769783 0.0066513553420362 1.0 0.031534295161777 2 Q07812 1 +Macromolecule depalmitoylation 0.8823259908937914 2.7114987002437374 0.0066979803656612 1.0 0.0316871526389802 5 Q9NUJ1,Q9UMR5,P50897 3 +Autophagy of nucleus 0.7019828351583348 2.710595471939814 0.006716251017748 1.0 0.0317281651009986 2 Q7Z3C6 1 +Tetrapyrrole metabolic process 0.6350668471763794 2.70887025305328 0.0067512735822234 1.0 0.0318480850142149 21 O00264,P22830,P09601,P30519 4 +Cell motility involved in cerebral cortex radial glia guided migration 0.7002071618822178 2.7009330297771137 0.0069145259974656 1.0 0.0324330037737761 2 O94901 1 +Negative regulation of amine transport 0.6981355430600812 2.6896456427636335 0.0071527927338999 1.0 0.0333376637364911 2 O75915 1 +Negative regulation of amino acid transport 0.6981355430600812 2.6896456427636335 0.0071527927338999 1.0 0.0333376637364911 2 O75915 1 +Response to granulocyte macrophage colony stimulating factor 0.6978395975140617 2.6880318793358637 0.0071874534396048 1.0 0.0333580616449074 2 P31749 1 +Regulation of macrophage proliferation 0.6978395975140615 2.6880318793358637 0.0071874534396048 1.0 0.0333580616449074 2 P27361 1 +Positive regulation of macrophage chemotaxis 0.6978395975140615 2.6880318793358637 0.0071874534396048 1.0 0.0333580616449074 2 P27361 1 +Positive regulation of macrophage migration 0.6978395975140615 2.6880318793358637 0.0071874534396048 1.0 0.0333580616449074 2 P27361 1 +S adenosylmethionine cycle 0.6975436519680418 2.68641779577407 0.0072222717454841 1.0 0.0334961361164245 2 O43865 1 +Negative regulation of blood circulation 0.7598888540417563 2.685419605976096 0.0072438799419354 1.0 0.0335727928024202 3 P05023 1 +Organelle fusion 0.5189595520841711 2.684281622551144 0.0072685850646976 1.0 0.033618118076774 48 Q13277,Q13190,Q8N2A8,P06493,Q9NX63,O95721,Q9Y6C9,Q9GZY8,P51809,O43752,O60313,P31751,Q07812,Q8IWA4,Q9BZG1,O15400,O60499,Q9Y4W6,Q9P253,O95249,Q12981 21 +Fucose metabolic process 0.8219917990903831 2.678005427740767 0.0074062018159835 1.0 0.0341877459909547 4 Q9BTY2,P04066 2 +Positive regulation of mitophagy 0.8216490851624926 2.676399235459584 0.0074417939536803 1.0 0.0342815565810065 4 P21796 1 +Positive regulation of long term synaptic potentiation 0.8216046148861817 2.6761907942186847 0.007446424099391 1.0 0.0342815565810065 4 Q13501,P05067 2 +Cytochrome complex assembly 0.7400745638166764 2.67589152569237 0.0074530763269984 1.0 0.0342815565810065 14 O75880,Q8N8Q8,Q9BSK2,Q6DKK2,Q9Y2R0,Q69YU5 6 +Sodium ion export across plasma membrane 0.7572528123149757 2.6721219659932376 0.0075373247400838 1.0 0.0345691736344303 3 P05026,P05023 2 +Regulation of mast cell activation involved in immune response 0.7570694262079487 2.6711960605994327 0.0075581486113951 1.0 0.0345926621694671 3 P09601 1 +Cellular homeostasis 0.3864522587006722 2.6677332231725273 0.0076364867500839 1.0 0.0348306010568013 150 Q92544,Q15907,Q9NWS0,P50897,Q05086,P05023,Q96PU5,P05026,Q9BPX6,Q9BWH2,P06576,P52789,P51572,P16615,P62995,Q8N183,O75880,P09601,P07686,P05067,Q8N5M9,Q9Y487,P0DP25,Q8N511,Q9NWR8,Q96TC7,P62258,P98194,Q93050,Q07812,Q7L0J3,Q9NQC3,P0CG08,O75503,O76024,P13473,Q96A33,P61421,Q99808,P09622,P54105,O95202,Q9Y6M7,Q8NE86,Q07820,Q9HD20,P10253,Q9HC07,Q9Y4W6,Q9Y263,P22413,Q8IYU8,Q8NEW0,P27361,P51790,O60826 56 +Phosphatidylglycerol acyl chain remodeling 0.7548845470692486 2.660156668133738 0.0078104311639428 1.0 0.0355014168890189 3 Q92604,Q96JX3 2 +Signal peptide processing 0.869791285825174 2.655973908026416 0.0079079732709332 1.0 0.0357481500325568 5 P67812,Q8TCT9 2 +Vacuolar acidification 0.8686822478708964 2.652716467967675 0.0079846910928029 1.0 0.0359964689170087 8 P50897,Q93050,Q8N511,Q9Y487 4 +Endocytosis 0.3935541635459316 2.65150896370154 0.0080132985951635 1.0 0.0361008114624647 131 P50897,Q05086,Q14108,P61978,P46934,Q9NX40,O15118,O15260,P20339,P05067,Q9UBG0,O60749,P09496,O15126,Q14C86,P0DP25,Q5VW38,P10909,Q96D71,Q9Y5X3,Q8WTV0,Q9BZG1,P61020,P57105,Q9H223,P22413,Q9NZQ3,P51790 28 +Intracellular distribution of mitochondria 0.7504566213059225 2.6377382429336316 0.0083460976735119 1.0 0.0371693797333155 3 O75153 1 +Glycosphingolipid biosynthetic process 0.8132250293985351 2.636819249259517 0.0083687410754311 1.0 0.0372451244225755 4 Q99805,Q16739 2 +Organophosphate ester transport 0.5752328326492292 2.6355837284678993 0.0083992700962849 1.0 0.0373558385372457 30 Q9H2D1,Q14108,Q8TB61,Q9BSK2,O43808,P61916,Q08722,Q8WTV0 8 +Respiratory electron transport chain 0.4877949017049219 2.6329905581550355 0.0084636700168716 1.0 0.0375160262518475 54 O43674,Q9UDW1,P20674,O75438,P06493,O43676,O75306,Q9H3K2,P00403,P43304,P21912,O95168,O75208,O95298,Q9Y6M9,P13073,P04062,P14927,O75746,O14949,P56556,P09622,O75489,P03886,Q9H936,P15954,P10606,O14548 28 +Activation of protein kinase c activity 0.687481503403378 2.631347914933012 0.0085046922344913 1.0 0.037596997309534 2 Q99623 1 +Glycosylation 0.5051680127745986 2.630850174978872 0.008517157492015 1.0 0.0376269344015559 50 O60762,Q8TCJ2,Q9H9S5,Q9BT22,O15118,O43505,O60476,Q9BXS4,Q10472,P04062,P33908,Q9Y2G5,Q9H0U3,O75503,P46977,Q86YN1,O60502,Q9HC07,P04843 19 +Positive regulation of er associated ubiquitin dependent protein catabolic process 0.7486689505196134 2.628669938187061 0.0085719514324253 1.0 0.0377932134869242 3 Q9UMX0 1 +Establishment of protein localization to organelle 0.3798823396568216 2.6240536095074556 0.0086890107519395 1.0 0.0381819628055639 193 O60830,Q9UHB9,Q9NS69,O14925,Q9BRG1,Q14108,O14737,Q99595,P46934,P55786,P40855,P51572,Q8N4H5,P31749,Q9GZY8,Q99442,P11279,O43615,P49257,Q9Y5J7,Q9Y5J9,P0DP25,Q9Y5Y5,Q15629,Q9Y5L4,Q9Y512,Q92973,P33908,P10909,Q07812,Q3ZCQ8,O95831,O43464,O60220,P46379,Q9Y5M8,Q8N8Q8,Q13501,O43681,P30536,Q10713,Q8N1F7,Q15388,O75381 44 +Carbohydrate derivative catabolic process 0.5502222602149128 2.6228594616059793 0.008719523209864 1.0 0.0382651586281482 34 Q9NUJ1,P00813,Q9H773,P04062,P33908,P04066,P16278,P15586,O60502,Q9BTY2,P06865,P17900,P54802,P06280 14 +Aminoglycan catabolic process 0.8610781990521288 2.6171561134419625 0.0088665779458134 1.0 0.0387560936798156 5 P15586,P54802,P16278,P04066 4 +Glycosaminoglycan catabolic process 0.8610781990521288 2.6171561134419625 0.0088665779458134 1.0 0.0387560936798156 5 P15586,P54802,P16278,P04066 4 +Regulation of systemic arterial blood pressure mediated by a chemical signal 0.808031602475399 2.6123230123288192 0.0089929242307504 1.0 0.0391787977857811 4 P42892 1 +Aminoglycan metabolic process 0.7122606645176645 2.6111372613645276 0.009024166545331 1.0 0.0392631446333723 15 Q9NX62,Q8NCH0,P04066,P15586,O43505,Q7LGA3,P06865,P16278,P54802 9 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.7448194197750098 2.6091084012017904 0.0090778480469211 1.0 0.0394092825825204 3 Q9UIQ6,P04439 2 +Regulation of cysteine type endopeptidase activity 0.4942661203526505 2.607683571121266 0.009115717779178 1.0 0.0395054287230084 52 O14737,Q15375,O00571,P51572,P31749,P78318,P16435,Q15041,Q99538,Q96K76,Q9BXK5,Q96A26,O95831,O43464,Q15392,Q9NR28,Q9NZJ7,Q9Y3B8,O75915 19 +Glycolipid biosynthetic process 0.7715859874515509 2.5970900125196055 0.0094017282861822 1.0 0.0404794933181618 11 O60762,Q99805,Q16880,Q8NBX0,O43292,Q16739 6 +Regulation of triglyceride metabolic process 0.8031194687023562 2.58908648602565 0.0096230922243314 1.0 0.0411111936073733 4 Q8WTV0 1 +Glycolipid transport 0.8018951732306717 2.58328485951127 0.0097864482537974 1.0 0.0417550913552921 4 P07602,P61916,Q9NZJ7 3 +Amino acid transmembrane transport 0.6903869346505808 2.579917327143893 0.0098823970562447 1.0 0.0420829652994338 16 Q96NB2,Q9Y619,Q15041,P30825,Q9H936,O75915,O75746,O60831,Q9H9B4,Q96QD8,Q15758,P08195 12 +Ph reduction 0.753108330909254 2.5775049509261327 0.0099516455899713 1.0 0.0423231749763945 12 P50897,Q8N511,Q05086,Q93050,P0CG08,O75503,P51790,Q9Y487 8 +Anterior posterior axis specification 0.8761387736475071 2.5656391875429767 0.0102985893277289 1.0 0.0434354670497516 7 Q15363,Q8N2A8,Q5T9L3,Q9UK61 4 +Positive regulation of b cell activation 0.7507950088269302 2.5652109580833176 0.0103113091929307 1.0 0.0434613791173976 12 P00813,P14174 2 +Positive regulation of necrotic cell death 0.848305257100225 2.5599203943328543 0.0104696142330453 1.0 0.0440163361744255 5 P00403 1 +Vesicle tethering 0.7960699919016206 2.5556250395076967 0.0105997270265698 1.0 0.0444784735991112 4 O95772 1 +Glutamate receptor signaling pathway 0.7949739212807706 2.5504102295808786 0.0107596229776363 1.0 0.0449212560070742 4 P05067 1 +Cellular respiration 0.3961549475100627 2.546245387311843 0.0108888614074826 1.0 0.0450740926311024 109 P56385,P14406,Q9UDW1,Q9BSK2,P20674,O43674,P00846,O75874,O43676,P06576,P06493,O75438,O75306,O75964,Q9H3K2,P00403,P43304,Q8NC60,P21912,P48735,O95168,O75208,O95298,Q9Y6M9,P13073,P04062,P14927,P24539,O14949,Q9BRT2,Q9NZ45,P36542,P09622,O75489,P03886,P22695,Q9H936,P15954,P10606,Q13423,P56134,O14548 42 +Negative regulation of blood pressure 0.8450566222713025 2.545300181733964 0.0109183832898267 1.0 0.0450740926311024 5 P42785,Q9HB40 2 +Glycosphingolipid metabolic process 0.7320384041554022 2.5450435256093087 0.0109264117755487 1.0 0.0450740926311024 13 P04062,P17900,Q99805,Q16880,Q07812,P06865,Q16739,P16278,P06280 9 +Lipid metabolic process 0.3575610395357739 2.5399152775735514 0.0110879324658099 1.0 0.0450740926311024 297 P50897,P05023,Q15125,Q5T8D3,P48651,Q9BT22,Q16739,Q13011,P06576,Q9HB40,Q13510,Q9H6V9,Q99538,Q9HBU6,P07602,O15254,Q9NPH0,O00116,Q9BQE5,Q14849,P83111,P14174,P50416,P04062,Q8NHP8,Q16880,Q96JX3,O14734,Q07812,O75844,O14773,P28288,Q8WTV0,O95470,Q86YN1,P35790,P16220,Q8IXJ6,P30536,P06865,O60762,P51648,Q9Y394,Q9BWD1,Q9Y2B2,Q16850,Q9H3P7,Q8IY17,P17900,Q92604,Q96AA3,O95864,P27544,Q8TBX8,P05067,Q15800,Q9UKU0,Q15067,P38435,Q8NBX0,Q9HCL2,Q96G23,P07099,O43464,Q8N2K0,P04066,Q10713,O43292,Q9H6K4,Q05639,P06280,Q9UBV2,O15269,Q8N2A8,O75874,O15118,Q9P035,P61916,Q14534,Q9UG56,P53985,Q9BVG9,Q99735,P31751,P10909,Q15392,Q9NZJ7,Q99805,Q96N66,O43808,O75845,Q9NX62,P16278,Q86UY6,P31749,P16435,Q14739,Q86UL3,O95674,A1L0T0,Q8WXW3,Q53GQ0,Q6NUM9,O43681 104 +Regulation of retrograde protein transport er to cytosol 0.7927154278945763 2.5396546033568153 0.0110961990906663 1.0 0.0450740926311024 4 Q9GZP9,P51572,Q13438 3 +Negative regulation of nitric oxide metabolic process 0.7924193070772816 2.5382433556078574 0.0111410483762559 1.0 0.0451521671018535 4 P30536,Q92945,P06280 3 +Cop9 signalosome assembly 0.6706126072802652 2.5381863479880984 0.0111428634503136 1.0 0.0451521671018535 2 Q99627 1 +Regulation of long term neuronal synaptic plasticity 0.7899658905477132 2.5265416999734778 0.0115191712443687 1.0 0.0460279339504431 4 P05067 1 +Aerobic respiration 0.4128770571289084 2.5242196620375275 0.0115955448043876 1.0 0.0460789774437885 92 P56385,P14406,Q9UDW1,Q9BSK2,P20674,P00846,O75874,O43676,P06576,O75438,O75306,O75964,Q9H3K2,P00403,P48735,O75208,O95298,P13073,P24539,O14949,P36542,P09622,O75489,P03886,P22695,P15954,P10606,Q13423,P56134 29 +Glycoprotein catabolic process 0.788569736452466 2.519875356656487 0.0117396397175777 1.0 0.0464038749362866 4 O60502,Q8TCJ2,P33908 3 +Blastoderm segmentation 0.8383252314752347 2.5149244242132855 0.0119057902508623 1.0 0.0470044012950712 5 Q8N2A8,Q9UK61 2 +Lipoprotein catabolic process 0.8374752957998461 2.511081195278729 0.0120362009269816 1.0 0.0473777557632053 5 Q9NUJ1,P50897 2 +Transition metal ion transport 0.7249250555244113 2.5060199320320384 0.0122098736656555 1.0 0.0479393392509655 13 O15173,P98194,Q9HD20,Q9HC07,Q8NEW0 5 +Response to oxidative stress 0.394830031727393 2.50544778722436 0.0122296453286621 1.0 0.0479393392509655 100 Q05086,P28074,Q9UMX0,Q8N0U8,P09493,P30519,Q86Y07,O75874,P06493,O75306,Q99720,P16615,Q9UL15,P31749,O43169,P09601,Q6NUK1,P05067,O95168,O75569,P04062,O95831,O43464,Q15392,Q15165,Q9NR28,P48637,Q07820,P00374,Q8IXJ6,O75915,O95747,P23246 33 +Negative regulation of t cell apoptotic process 0.7243536559847541 2.504325591717743 0.0122685075490245 1.0 0.0480631691710154 3 P00813 1 +Positive regulation of hexokinase activity 0.7240047159555113 2.5025275342210236 0.0123310033438364 1.0 0.0482507999404469 3 Q9UNI6 1 +Regulation of hexokinase activity 0.7240047159555113 2.5025275342210236 0.0123310033438364 1.0 0.0482507999404469 3 Q9UNI6 1 +Serine transport 0.7847201658276521 2.5014668589456344 0.0123680017540528 1.0 0.0483097657166283 4 Q9H9B4,Q96QD8,Q96NB2 3 +Vitamin d metabolic process 0.7843224856337169 2.499562856706266 0.0124346637860317 1.0 0.0485414606981003 4 P38435,P04062 2 +Lysosomal protein catabolic process 0.8082761958551401 2.4985844930873293 0.0124690414015093 1.0 0.0486029347353503 9 Q8N511,P04062 2 +Protein catabolic process in the vacuole 0.8082761958551401 2.4985844930873293 0.0124690414015093 1.0 0.0486029347353503 9 Q8N511,P04062 2 +Neuron apoptotic process 0.4874555150528101 2.4984869492993194 0.0124724734923822 1.0 0.0486029347353503 51 P07196,Q9NR28,P50897,Q92542,P04062,Q15058,P09601,Q96A26,Q99538,Q07820,Q01105,Q15375,P05067,P31751,Q07812,O95831,Q15233,Q99720 18 +Selective autophagy 0.5643217038206711 2.497996482547118 0.01248974331045 1.0 0.0486415518790597 29 P12235,Q9UMX0,P27544,P53365,Q13501,Q5T8D3,Q16543,P21796,O15269,Q9NQ88,Q96HY6,Q9Y6I9,O43464,P27361 14 +Rna stabilization 0.5811892783715952 2.4971879276798337 0.0125182595552619 1.0 0.0487238971735726 26 Q14011,Q08J23,Q92804,P67809,Q14103,Q13151,O60506,P35637,P98175 9 +Maintenance of protein localization in endoplasmic reticulum 0.8316192395874882 2.4845534159598577 0.0129714046108277 1.0 0.0500823106678495 5 O43731,O43292,P24390 3 +Protein retention in er lumen 0.8316192395874882 2.4845534159598577 0.0129714046108277 1.0 0.0500823106678495 5 O43731,O43292,P24390 3 +Atp synthesis coupled electron transport 0.5208986898177151 2.48271632599702 0.013038487321433 1.0 0.0502164118341208 41 Q9UDW1,P20674,O75438,P06493,O43676,O75306,Q9H3K2,P00403,O95168,O75208,O95298,P13073,P14927,O14949,P09622,O75489,P03886,P15954,P10606,O14548 20 +Microglial cell activation 0.7806391165853984 2.4819071328133777 0.0130681328322723 1.0 0.0503012754155434 4 P10909,P05067 2 +Alcohol metabolic process 0.4267024033753682 2.472657258970367 0.0134112694304013 1.0 0.0514557747789976 81 P51648,Q9NX62,Q15125,O15269,Q16850,O75874,Q13510,O15118,P16435,Q14739,P05067,P61916,Q9BQE5,P48735,Q14849,Q15800,Q14534,P04062,P61457,Q8WTV0,Q15392,P00374,O75845,Q10713 24 +Endoplasmic reticulum membrane organization 0.8293853371746357 2.4725636350243803 0.0134147828634003 1.0 0.0514557747789976 8 Q9P2W9,Q15041,Q15363,Q9NQC3,Q8NHH9,Q12981 6 +Glyoxylate metabolic process 0.7178609815989291 2.470805859017864 0.01348089823147 1.0 0.0516194996592036 3 P48735 1 +Negative regulation of organic acid transport 0.7757963642827166 2.4586374325178824 0.0139465385304564 1.0 0.0530337590033295 4 P31749,P31751 2 +Establishment of protein localization to mitochondrial membrane 0.619334949398544 2.4541794253846785 0.0141206505260436 1.0 0.0535418125798176 19 Q9NS69,Q9Y5L4,Q9Y512,O14737,Q8N8Q8,Q9Y5J7,O60220,Q9Y5J9,P0DP25 9 +Mitochondrial electron transport ubiquinol to cytochrome c 0.8248075399497503 2.453591072554257 0.0141437719384436 1.0 0.0535987320763612 5 Q9UDW1 1 +Peroxisome fission 0.7745774921727893 2.4527705358386567 0.0141760736241027 1.0 0.0536903556342093 4 Q9GZY8,P40855 2 +Negative regulation of cell killing 0.7140254983052747 2.4509412053679553 0.0142483224486003 1.0 0.0538899797304581 3 P01889 1 +Protein transport within lipid bilayer 0.6549274933412301 2.4506110275458934 0.0142613972686596 1.0 0.0538899797304581 2 P05026 1 +Positive regulation of t cell mediated cytotoxicity 0.823918724328123 2.449542607288319 0.0143037785641753 1.0 0.05398839093697 5 P01889,O15400,Q9NUQ9 3 +Regulation of t cell mediated cytotoxicity 0.823918724328123 2.449542607288319 0.0143037785641753 1.0 0.05398839093697 5 P01889,O15400,Q9NUQ9 3 +Neuron death 0.423439489487705 2.445430666736049 0.0144679263399125 1.0 0.0544834901313288 79 P07196,P50897,Q15058,Q15375,Q01105,Q99720,P31749,Q9UL15,P09601,Q99538,P05067,Q15233,P04062,Q96A26,Q9UMX5,P31751,P10909,Q07812,O95831,O76024,O43464,Q15392,Q9NR28,Q92542,Q07820,P49841,Q9NQ88,O75915 28 +Membrane fusion 0.4967827958716195 2.4402198931159056 0.0146783241777361 1.0 0.0549315087716072 47 Q9P2W9,Q13277,O95721,O15400,O15498,Q13190,O60499,P31751,O95249,Q12981,Q8IWA4,O43752,Q9BZG1 13 +Phosphatidylethanolamine metabolic process 0.7710332736704797 2.4356876476598313 0.0148635130742853 1.0 0.0555616277759908 4 Q9HBU6,Q9UG56 2 +Respiratory chain complex iii assembly 0.8465520998824339 2.433984189898695 0.0149336473556036 1.0 0.0557292351062589 7 Q9BSK2,Q69YU5 2 +Suckling behavior 0.7696816325188327 2.429163725458519 0.0151336964897581 1.0 0.0563485070990488 4 P05067 1 +Fatty acid alpha oxidation 0.7690558101353253 2.4261413851796614 0.0152603238728183 1.0 0.056692231858042 4 O43808 1 +L amino acid transport 0.7104079972895271 2.4258255837274043 0.0152736087247644 1.0 0.0567097078999822 13 Q9Y619,Q15041,P30825,Q9H936,O75915,O75746,O60831,Q9H9B4,Q96QD8,Q15758,P08195 11 +Organelle membrane fusion 0.5282819893553855 2.422674018134313 0.0154067448015708 1.0 0.0570437962989255 33 Q13277,O95721,O15400,Q13190,O60499,P31751,O95249,Q12981,Q8IWA4,O43752,Q9BZG1 11 +Pinocytosis 0.8184825344118335 2.4218932856640096 0.0154398838490541 1.0 0.0571344862029109 8 P50897,Q9Y5X3,Q9BZG1 3 +Regulation of electron transfer activity 0.7081113084665471 2.4202183619149973 0.0155111895645123 1.0 0.0573220939205666 3 Q99623,O00483 2 +Peripheral nervous system myelin maintenance 0.7673812378258472 2.418048917048156 0.0156039789644195 1.0 0.057580511990982 4 Q8N3R9,P31751 2 +Acylglycerol homeostasis 0.7072843239835209 2.4159134446202213 0.015695791949013 1.0 0.057854706631917 3 Q8WTV0 1 +Cellular hormone metabolic process 0.6133697131247292 2.4145618050971516 0.015754149935363 1.0 0.0580051124918186 19 Q53GQ0,O95470,Q9Y394,Q6NUM9,P42892,P30536,Q14849,Q9HB40,Q8NBQ5 9 +Iron ion homeostasis 0.6463692164273793 2.412213330030067 0.015856000987134 1.0 0.0583151421947516 17 P09601,P30519,Q9Y487 3 +Regulation of protein folding 0.8155136551867392 2.4111624935558917 0.015901761948013 1.0 0.0584331779482109 5 Q9UL15,Q9H2J4,O14737 3 +Embryonic pattern specification 0.8161621171676332 2.411070396382934 0.0159057780494524 1.0 0.0584331779482109 8 Q15363,Q8N2A8,Q9UK61 3 +Positive regulation of peptidase activity 0.5004192847796316 2.409897450643027 0.0159570050189008 1.0 0.0585822158014742 45 Q9NR28,Q92542,Q9BXK5,O14737,Q9NZJ7,Q96A26,Q99538,Q9UL46,P05067,O75915,Q96HY6,O00571,O95831,P61289,O43464,P51572 16 +Cell fate determination 0.7060983253886222 2.409735832643808 0.0159640748461877 1.0 0.0585822158014742 3 Q07820 1 +Embryonic axis specification 0.8654456281469685 2.408976023791914 0.0159973488910498 1.0 0.0586717418540225 6 Q15363,Q8N2A8,Q9UK61 3 +Protein import into peroxisome matrix 0.765382708076159 2.4083807910338217 0.0160234582910354 1.0 0.0587179768996052 4 Q9Y5Y5 1 +Protein import into mitochondrial matrix 0.7891448176067647 2.4061888197648384 0.0161199306065107 1.0 0.058990377285952 9 O60830,O14925,Q99595,O43615,Q3ZCQ8,Q15388 6 +Calcium ion export across plasma membrane 0.7048549437536968 2.4032544833980523 0.0162498746403703 1.0 0.0592887072933083 3 P62258,P0DP25 2 +Negative regulation of mrna catabolic process 0.5771403865017132 2.39792392484445 0.016488289277055 1.0 0.0600127471019926 24 Q14011,Q92804,P67809,Q14103,Q13151,Q99729,O60506,P35637,P98175 9 +Mitochondrial adp transmembrane transport 0.7036708111308363 2.397077371617355 0.0165264336095645 1.0 0.0600127471019926 3 P12235,P12236 2 +Nucleobase transport 0.7036708111308264 2.3970773716173057 0.0165264336095667 1.0 0.0600127471019926 3 P12235,Q9Y277 2 +Positive regulation of erad pathway 0.7624561335752428 2.394203265648022 0.0166565150797683 1.0 0.0603855777082772 4 P51572,Q9UMX0 2 +Positive regulation of mitochondrion organization 0.580918161649414 2.3935291324599097 0.0166871560725951 1.0 0.060463494782775 23 P12235,P27544,O14737,Q96A26,Q9GZY8,Q8NE86,P21796,Q8N2A8,Q07812,O43464,Q9UII2 11 +Glycoside catabolic process 0.8613333333333167 2.391105708801779 0.0167977157051748 1.0 0.0607309097896611 6 Q9NUJ1,P04062,P04066,Q9BTY2,P06280 5 +Nadh dehydrogenase complex assembly 0.5439614064289165 2.3903483652142987 0.0168323982978197 1.0 0.0607897925411426 30 O95298,Q9Y6M9,P56556,Q15070,Q8N183,Q9NX14,O75489,O43674,Q96CU9,P03886,O95168,O75438,O43676,O75306,Q86Y39,Q9H061 16 +Regulation of response to extracellular stimulus 0.8105498971690115 2.3884148981148434 0.016921226765876 1.0 0.0609440804881061 5 P80303 1 +Retrograde transport endosome to golgi 0.5153368884772558 2.385597131542097 0.017051418884975 1.0 0.0613127461429816 39 O15260,O15498,Q13190,Q9BVK6,O60499,O95249,Q9Y5X3,O75503,O60749,O43752 10 +Negative regulation of mononuclear cell migration 0.7012742191228603 2.3845616153341997 0.0170994842752392 1.0 0.0613520584012247 3 P31749 1 +Protein targeting to membrane 0.5144399560370483 2.3777452423301253 0.0174188556640961 1.0 0.0622613396884865 39 Q9Y5Y5,Q15629,P46379,O60725,Q15041,Q9GZY8,Q99442,P31751,O43681,P40855,P27105,P43307 12 +Negative regulation of anion transport 0.6983422143280122 2.3692246940272126 0.0178254204083685 1.0 0.0634698587647576 3 Q9HD26,O75915 2 +Regulation of post translational protein modification 0.6983090494582819 2.3690510552054898 0.017833791455009 1.0 0.0634698587647576 3 O75718 1 +Outer ear morphogenesis 0.6980461811722812 2.367674650484379 0.0179002692388177 1.0 0.0636721632935125 3 O75569,P27361 2 +Regulation of macroautophagy 0.4552279907326066 2.3668273227944514 0.0179413014612521 1.0 0.0636728557745335 57 P31749,O15118,P12235,Q9UMX0,P27544,P04062,P09601,Q8TBX8,Q15382,P21796,Q9Y2S7,O15269,P46934,Q93050,P61421,Q9NQ88,Q9Y5X3,Q9Y487 18 +Circulatory system process 0.4156865712639839 2.3631713034023982 0.0181192920304296 1.0 0.064186690672439 77 P00813,P05023,Q96PU5,P09493,P05026,P42892,Q9HB40,P16615,P09601,Q6P179,Q9Y289,Q9NZ08,P0DP25,O75116,P53985,P62258,Q16625,Q9Y5X3,O75844,Q9UIQ6,Q96QD8,Q99808,P30825,P10253,P42785,P08183 26 +Branched chain amino acid transport 0.6392423794021953 2.3621115126730405 0.0181711754044686 1.0 0.064186690672439 2 P08195 1 +Leucine transport 0.6392423794021953 2.3621115126730405 0.0181711754044686 1.0 0.064186690672439 2 P08195 1 +Organic cation transport 0.8045023696682402 2.3606186972654952 0.0182444787056204 1.0 0.0643564466159411 5 Q96QD8,Q70HW3,Q99808,O43808 4 +Release of cytochrome c from mitochondria 0.6219021980635508 2.360508979004823 0.0182498765174041 1.0 0.0643564466159411 18 P31749,O14737,Q9Y3B8,Q96A26,Q9GZY8,P10909,Q3ZCQ8,Q9H3K2 8 +Peripheral nervous system axon regeneration 0.7554856476533675 2.3603401750170314 0.0182581839014812 1.0 0.0643564466159411 4 P30536,Q96G23 2 +Negative regulation of cholesterol metabolic process 0.6383545427641364 2.35707436906902 0.0184195575595826 1.0 0.0647870441252166 2 O75477 1 +Negative regulation of alcohol biosynthetic process 0.6383545427641364 2.35707436906902 0.0184195575595826 1.0 0.0647870441252166 2 O75477 1 +Neuromuscular synaptic transmission 0.6371707605800584 2.350353549008223 0.0187555867223854 1.0 0.0658288224366676 2 Q8IUD2 1 +Protein import 0.4034559712081145 2.342699269311628 0.0191448075104041 1.0 0.067087915857036 91 O60830,Q9NS69,O14925,O14737,Q99595,O96008,P40855,P31749,O43615,Q9Y5Y5,Q9Y512,Q92973,P10909,Q3ZCQ8,O95831,P13473,Q13501,Q8N1F7,Q15388,O75381 20 +Response to increased oxygen levels 0.7743678229904498 2.3341378508805564 0.019588504898788 1.0 0.0682448228129099 9 P00846,Q9Y487 2 +Convergent extension 0.6902784871571402 2.3269020286649944 0.0199704802177169 1.0 0.0691744778610542 3 Q13263 1 +Ceramide catabolic process 0.7972357910393867 2.322283627807179 0.0202176685295008 1.0 0.0698476588141509 8 Q13510,P06865,P17900,P04062 4 +Presynaptic modulation of chemical synaptic transmission 0.6315477952056875 2.3183573941219997 0.0204299055607162 1.0 0.0704703788365206 2 Q00535 1 +Aggrephagy 0.746805375610222 2.317983147194582 0.0204502369870509 1.0 0.0705037121791443 4 Q13501,Q9UMX0 2 +Positive regulation of cysteine type endopeptidase activity 0.528183476259014 2.3164513237871573 0.0205336392373234 1.0 0.0707543387484205 31 Q9NR28,Q9BXK5,O14737,Q9NZJ7,Q96A26,Q99538,O75915,O00571,O95831,O43464,P51572 11 +Regulation of phospholipase c activity 0.6876850207223191 2.313245746223353 0.0207091317192047 1.0 0.0712396968950404 3 Q99623,P00533 2 +Activation of phospholipase c activity 0.6876850207223191 2.313245746223353 0.0207091317192047 1.0 0.0712396968950404 3 Q99623,P00533 2 +Male genitalia development 0.6876557408609448 2.313091445342703 0.0207176119582792 1.0 0.0712396968950404 3 Q15392 1 +Regulation of nitric oxide metabolic process 0.7035637706270508 2.310275729595593 0.0208728937299234 1.0 0.0714886076974591 12 P31749,P10909,Q08722,P30536,Q92945,P06280 6 +Ceramide transport 0.7935847721282195 2.310209941055348 0.0208765339470564 1.0 0.0714886076974591 5 P07602,Q9NZJ7 2 +Regulation of mast cell activation 0.7445004637785121 2.3067008915190064 0.0210715005264794 1.0 0.0717023606810785 4 P09601 1 +Ganglioside metabolic process 0.7444326983140159 2.3063689657127946 0.0210900245497971 1.0 0.0717023606810785 4 P06865 1 +Ganglioside catabolic process 0.7444326983140159 2.3063689657127946 0.0210900245497971 1.0 0.0717023606810785 4 P06865 1 +Pigment metabolic process 0.5459584940418255 2.306354284959659 0.0210908441767312 1.0 0.0717023606810785 28 P00813,O00264,P09601,P22830,P30519 5 +Regulation of tolerance induction 0.6861227000881978 2.3050086797469347 0.0211660873054735 1.0 0.0719211676102183 3 P01889 1 +Glycolytic fermentation 0.6858814638284041 2.30373610381777 0.0212374618505406 1.0 0.0720895661891233 3 Q9NQ88 1 +Fermentation 0.6858814638284041 2.30373610381777 0.0212374618505406 1.0 0.0720895661891233 3 Q9NQ88 1 +Positive regulation of amyloid precursor protein biosynthetic process 0.6852714284008588 2.300517194059178 0.0214189363140189 1.0 0.0725937179996672 3 Q92542 1 +Protein o linked glycosylation via serine 0.6850207223208921 2.2991939728314756 0.0214939271166756 1.0 0.0727490933883084 3 Q10471,Q10472 2 +Cardiac neural crest cell differentiation involved in heart development 0.6850077867034126 2.2991256934429973 0.0214978029032177 1.0 0.0727490933883084 3 P27361 1 +Response to cell cycle checkpoint signaling 0.684600569714186 2.2969759635098073 0.0216201409596801 1.0 0.07301354706312 3 O75844 1 +Intermediate filament bundle assembly 0.7407746689086359 2.2884325226683297 0.0221123454858607 1.0 0.0743717513058796 4 P07196 1 +Positive regulation of histone phosphorylation 0.6814683244523267 2.280422781457432 0.0225826257420984 1.0 0.0754542838875271 3 P27361,P50750 2 +Potassium ion homeostasis 0.7388214391471677 2.2788400827544484 0.0226765732369773 1.0 0.0755528681648877 4 P05026,P05023,P54709 3 +Cellular potassium ion homeostasis 0.7388214391471677 2.2788400827544484 0.0226765732369773 1.0 0.0755528681648877 4 P05026,P05023,P54709 3 +Protein localization to basolateral plasma membrane 0.6244451021012187 2.2777705195741795 0.0227402536435292 1.0 0.0756748924119259 2 P61026 1 +Hormone metabolic process 0.5359176562012563 2.275781049086183 0.0228591175442456 1.0 0.0759841232429983 29 Q53GQ0,O95470,Q9Y394,P05023,P16435,P07858,Q6NUM9,P42892,P30536,O75844,Q14849,Q9HB40,Q8NBQ5 13 +Nucleotide transport 0.6972544596777004 2.275649021512519 0.0228670247936246 1.0 0.0759841232429983 12 Q9H2D1,Q99808,P12236,Q8TB61,Q6NUK1,Q9BSK2,O43808,Q08722 8 +Regulation of amyloid fibril formation 0.8115653311146193 2.27563827523934 0.0228676685020916 1.0 0.0759841232429983 7 P10909,O15212,P05067 3 +Response to l glutamate 0.7378969234738199 2.274296047313082 0.0229481926660024 1.0 0.0761750905723808 4 O95831 1 +Middle ear morphogenesis 0.7376976696130852 2.273316396236145 0.0230071201681598 1.0 0.0763323580277954 4 O95747,P54802 2 +Retina morphogenesis in camera type eye 0.7375603417622529 2.2726411465443133 0.0230478139383931 1.0 0.0763984403587819 4 Q15555,P54802 2 +Mitochondrial proton transporting atp synthase complex assembly 0.737412006112947 2.2719117122402386 0.0230918433546432 1.0 0.0764599161978141 4 Q9BUB7,Q8N5M1 2 +Negative regulation of mitophagy 0.6797607131398884 2.271385175213921 0.0231236710560485 1.0 0.0765269614468826 3 Q9NQ88 1 +Cartilage development involved in endochondral bone morphogenesis 0.7371977520503141 2.270858019532299 0.0231555743083122 1.0 0.0765941894913092 4 O75844 1 +Behavior 0.4098440944624824 2.2694378045490584 0.023241715417916 1.0 0.0768406689329702 86 P50897,Q05086,Q9GZP9,P17900,Q9BPZ3,O15118,P31749,O00264,Q99538,P05067,P54802,P53985,P04062,O75844,O43464,Q8N2K0,Q92542,P10253,P30536,O75915,P51790 21 +Positive regulation by symbiont of entry into host 0.6226694288251017 2.2675940361221563 0.0233539615208768 1.0 0.0771731658457376 2 P07237 1 +Dicarboxylic acid transport 0.6065853610650579 2.260707720534728 0.0237773620776973 1.0 0.0782592559619031 18 Q9H2D1,Q02978,Q9BQT8,Q15041,Q9UBX3,Q9H936,P98164,O75915,O75746,Q9UJS0,P55011,O60831,Q15758 13 +L alpha amino acid transmembrane transport 0.7074589831704869 2.2593066727974285 0.0238643151294795 1.0 0.0784282738392491 11 Q9Y619,Q15041,P30825,Q9H936,O75915,O75746,O60831,Q15758,P08195 9 +Collateral sprouting 0.734676163508966 2.258447415403177 0.023917779451031 1.0 0.0785649127196143 4 P05067 1 +Regulation of peptidase activity 0.406676450568692 2.2578594202225735 0.023954425258529 1.0 0.0786461979799397 87 O14737,P07858,Q15375,Q96HY6,O00571,P61289,P51572,P31749,P78318,P16435,Q15041,Q99538,P05067,Q96K76,Q9BXK5,Q96A26,Q9UL46,O95831,O43464,Q15392,Q9NR28,P49755,Q92542,Q9NZJ7,Q9Y3B8,O75915 26 +Embryonic heart tube development 0.8306984511600533 2.2568029186066636 0.0240203922970003 1.0 0.0787072191167616 6 Q15363 1 +Endoplasmic reticulum tubular network organization 0.7069921062069677 2.256798832318471 0.0240206477467859 1.0 0.0787072191167616 11 Q9H6H4,Q15041,O95197,Q9NQC3,Q8NHH9,Q6NUK4 6 +Positive regulation of mitochondrial translation 0.8300834656554814 2.2540855742528008 0.0241907850138998 1.0 0.0791631751896693 6 Q9Y2R0 1 +Meiotic spindle assembly 0.6203018644569455 2.25400687945281 0.0241957351918795 1.0 0.0791631751896693 2 O95067 1 +Inflammatory response 0.4041676959715687 2.2516853342988172 0.0243421640981911 1.0 0.0795241534972541 73 P00813,P04062,P09601,Q99735,Q8IV08,P05067,Q9BQE5,P42785,P14174,Q8N2K0 10 +Aminophospholipid translocation 0.6197099733649063 2.250606785511459 0.0244104532726479 1.0 0.0797078486555978 2 Q9NV96 1 +Regulation of phospholipid catabolic process 0.732453383394049 2.2474928962175897 0.0246085440692422 1.0 0.0798677569946474 4 Q8WTV0 1 +Membrane docking 0.5196604669645032 2.246697472902157 0.0246593678726092 1.0 0.0798677569946474 31 Q9Y5Y5,Q13277,O95721,O15400,O15498,Q13190,O60499,O43752 8 +Negative regulation of mrna metabolic process 0.4798138732628929 2.246517774880313 0.024670862313648 1.0 0.0798677569946474 46 Q14011,P22626,Q15287,P26368,P61978,Q92804,P67809,O60506,Q14103,Q13151,Q99729,P50750,Q16629,P35637,P38159,P98175,P07910 17 +Antigen processing and presentation 0.543024383436302 2.2459944874681175 0.0247043610007984 1.0 0.0798677569946474 27 P61020,P04062,P04439,Q6P179,P01889,P10321,Q9UIQ6,Q9NZ08,Q9BZG1 9 +Negative regulation of rna catabolic process 0.5195351507515508 2.2456678901913176 0.0247252883660233 1.0 0.0798677569946474 31 Q14011,Q08J23,Q92804,P67809,Q14103,Q13151,Q99729,O60506,P35637,P98175 10 +Macrophage proliferation 0.7319089341429219 2.2448076075759764 0.0247804861857732 1.0 0.0799083618082457 4 P04062 1 +Interleukin 1 mediated signaling pathway 0.6746162815021245 2.2441014270964943 0.0248258761728856 1.0 0.0799083618082457 3 Q86Y07 1 +Vitamin transmembrane transport 0.8044400259170702 2.243034760675241 0.0248945730342908 1.0 0.0800624005759749 7 Q8WTV0,Q9H2D1,P04062 3 +Regulation of dendrite extension 0.6737714624037825 2.239612762865443 0.0251160734181299 1.0 0.0806503475894754 3 Q9Y263,Q96PU5 2 +Intrinsic apoptotic signaling pathway in response to dna damage 0.5468008749101527 2.2394569180018467 0.0251262014959494 1.0 0.0806503475894754 26 P46379,P61978,P09601,Q9Y3B8,Q07820,P10909,Q96K76,O43464,P14174 9 +Locomotory exploration behavior 0.67369920786212 2.2392287561301063 0.025141035703369 1.0 0.0806587888172649 3 Q05086 1 +Autophagy of mitochondrion 0.5125065591445637 2.2386246782001713 0.0251803471405374 1.0 0.0807457128829751 32 P12235,Q99623,P27544,P04062,P53365,Q13501,Q16543,P21796,Q9BWH2,Q9NQ88,P30536,P52789,O43464,Q9UII2 14 +Mitochondrial atp synthesis coupled proton transport 0.7022906271166444 2.231505399827509 0.0256476702342791 1.0 0.0818404509362313 11 P36542,P24539,P00846,P56134,P06576,O75964 6 +Positive regulation of anion transmembrane transport 0.7279207194938702 2.2251122942824724 0.0260737006198998 1.0 0.0829264135692581 4 Q15041 1 +Glycolipid catabolic process 0.7764599234669423 2.223770767630908 0.0261638711284815 1.0 0.0830886014917865 8 P17900,P06865,P04066,P04062 4 +Protein localization to endoplasmic reticulum exit site 0.726573406996992 2.218448832744628 0.0265242446789117 1.0 0.0836748129274119 4 P51572,O15027 2 +Regulation of water loss via skin 0.8214267939571357 2.2157469016571363 0.0267088408123004 1.0 0.0839366281162593 6 Q9Y3B8,Q16739,P04062 3 +Negative regulation of nik nf kappab signaling 0.7712071915865769 2.2059692762345096 0.0273861509837927 1.0 0.0856173471390189 5 O43657 1 +Negative regulation of leukocyte migration 0.7962810258927399 2.205553708175678 0.0274152633545459 1.0 0.0856342252255267 7 P09601,P00813 2 +Response to ether 0.7235780369609826 2.2036165598223714 0.0275513216849865 1.0 0.085971050526948 4 Q9H4A6 1 +Cellular response to reactive nitrogen species 0.7949060276996258 2.199221697345022 0.0278621622636106 1.0 0.0866546025412717 7 O95831,P24941 2 +Response to nitric oxide 0.7949060276996258 2.199221697345022 0.0278621622636106 1.0 0.0866546025412717 7 O95831,P24941 2 +Protein import into peroxisome membrane 0.7686744916895949 2.194093572686932 0.0282286832435545 1.0 0.0875884354726065 5 Q9Y5Y5 1 +Lipid droplet formation 0.721066661675282 2.191161837754815 0.0284400831303406 1.0 0.087914176524051 4 Q14534 1 +Negative regulation of autophagy of mitochondrion 0.7209792630557726 2.1907280868738463 0.0284714753200157 1.0 0.0879700703085478 4 Q9NQ88,P30536 2 +Endochondral bone morphogenesis 0.7676071013935479 2.189083908169722 0.0285907419060595 1.0 0.0882560547674674 5 Q9NX62,O75844 2 +Regulated exocytosis 0.4943960724052645 2.187092493984091 0.0287357724831629 1.0 0.0886623344263417 36 Q15907,Q13277,O95721,P16615,O43760,Q99584,P49755,P09601,P20339,P11279,Q7L0J3,Q4J6C6,P0DP25 13 +L aspartate transmembrane transport 0.7201658276576794 2.1866900768444184 0.0287651565075148 1.0 0.0887115815950377 4 Q15758,O75746,Q9H936 3 +Transition metal ion homeostasis 0.5483080680804321 2.185900663899616 0.0288228736706301 1.0 0.0888277946468797 24 Q8N511,P09601,P30519,P05067,Q9Y487 5 +Cellular response to oxygen levels 0.4926327465036213 2.18477680745888 0.0289052153532998 1.0 0.0889774421378474 39 P31749,Q8N511,Q9UMX0,Q99808,P09601,Q96A26,P61421,Q9NQ88,Q9Y4P3,O95831,P55786,O75306,Q9Y487 13 +Calcium ion export 0.7196117292449402 2.1839384096647536 0.0289667741252093 1.0 0.0891254237399945 4 O95202,P0DP25 2 +Vesicle organization 0.3721703802300871 2.181035798481089 0.0291807687737144 1.0 0.0894833203278407 104 Q9BRG1,Q14108,Q13190,Q9H4A5,O95721,O43633,Q9H4A6,Q2M389,O43752,Q9BVK6,P31751,Q15363,Q9NR31,Q9BZG1,P49755,P61020,O15400,Q13501,O60499,O95249,P51790 21 +Regulation of b cell apoptotic process 0.813588958938265 2.180891919859363 0.0291914115035292 1.0 0.0894833203278407 6 P00813 1 +Regulation of b cell activation 0.594379462912491 2.1803759524463984 0.0292296051858467 1.0 0.0895286937169657 18 P00813,P14174 2 +Collagen fibril organization 0.7904181115536723 2.178523289612967 0.0293671002625888 1.0 0.0898185871976331 7 P13674,Q92791 2 +Chloride transport 0.6796276565722452 2.178192583610013 0.0293917019931015 1.0 0.0898185871976331 12 Q9C0H2,P51798,Q9UHG3,P30536,Q96S66,P08183,P51790 7 +Mating 0.7902695881385756 2.1778374820410713 0.0294181382856455 1.0 0.0898185871976331 7 P00813 1 +Arf protein signal transduction 0.6621765395808172 2.177775768715399 0.0294227347513451 1.0 0.0898185871976331 3 Q15555 1 +Phosphatidylserine metabolic process 0.7650736151216081 2.1771820944224016 0.0294669837301917 1.0 0.0899110320742554 5 Q9BVG9,Q8N2K0 2 +Regulation of steroid biosynthetic process 0.6908657907860886 2.1697430651116156 0.0300263156613447 1.0 0.0913225587693637 11 P30536,Q13510,P16435 3 +Protoporphyrinogen ix metabolic process 0.7622908903001904 2.1640912456711434 0.0304573472521487 1.0 0.0923256466893039 5 P22830 1 +Regulation of skeletal muscle adaptation 0.65956187092955 2.163771998473325 0.0304818521827903 1.0 0.0923256466893039 3 P16615,Q13555 2 +Skeletal muscle adaptation 0.65956187092955 2.163771998473325 0.0304818521827903 1.0 0.0923256466893039 3 P16615,Q13555 2 +Negative regulation of leukocyte mediated immunity 0.7154538997566665 2.163263569917759 0.0305209133493558 1.0 0.0924016107768632 4 P09601,P01889 2 +Positive regulation of chemokine production 0.7627352922543106 2.158090455644501 0.0309207996751585 1.0 0.0933983386897272 8 P09601,O00571,P14174,P05067 4 +Locomotory behavior 0.5081692629723128 2.1518071392586315 0.0314125473301607 1.0 0.0944975439705225 31 O15118,P50897,P05067,P10253,O75844,O43464,P54802,Q8N2K0 8 +Regulation of protein exit from endoplasmic reticulum 0.7373214215703356 2.1508687668656385 0.0314865593983839 1.0 0.0946745546241672 9 Q92544,Q9GZP9,Q9NR31,Q13438,Q9Y6B6,P51572,P60604 7 +Negative regulation of glycoprotein metabolic process 0.7594290949411799 2.1506086140025897 0.0315071048501947 1.0 0.0946932496384432 5 Q9BXS4,Q9NQX7,Q9Y287 3 +Lipid biosynthetic process 0.3554618498308502 2.149741495401775 0.0315756682004988 1.0 0.0948518090650937 155 O60762,P05023,Q9NX62,Q15125,Q9Y2B2,P48651,O15269,Q16850,Q9H3P7,Q16739,O75874,Q13510,Q92604,O95864,P31749,P27544,P16435,Q14739,Q8TBX8,Q9P035,Q86UL3,Q9HBU6,Q9NPH0,O00116,O95674,Q15800,Q14849,Q9UKU0,P14174,Q14534,Q9UG56,P04062,Q9BVG9,Q16880,Q8NBX0,Q96JX3,Q9HCL2,O14734,Q8WXW3,Q96G23,P28288,Q8WTV0,Q15392,Q53GQ0,O95470,Q86YN1,P35790,Q99805,Q96N66,P16220,O75845,P30536,O43292,Q10713 54 +Cellular response to biotic stimulus 0.4882858110834592 2.1488581584410738 0.0316456454812581 1.0 0.0949800504021957 38 P31749,Q8WTV0,O76024,P49841,P08670,Q9NQ88,P30536,Q8IXJ6,Q86U42,Q9Y263,Q9NUQ9,O75844,Q96A33,Q86UE4,P14174 15 +Diol metabolic process 0.7838466044440705 2.1481295557778015 0.031703464880143 1.0 0.095067241103841 7 Q13510,P00374,O15269,P04062 4 +Diol biosynthetic process 0.7838466044440705 2.1481295557778015 0.031703464880143 1.0 0.095067241103841 7 Q13510,P00374,O15269,P04062 4 +Secretion 0.3549382841100628 2.1466303321320392 0.0318227231358145 1.0 0.0953815769635367 166 P00813,Q13277,P50897,Q15907,Q9UBV2,Q99584,O15498,Q92905,Q16850,O43768,P52789,P00403,Q9H4A5,P16615,Q5T9L3,O95721,Q96KC8,Q8N183,O43633,P09601,Q13505,P20339,P51151,Q9H4A6,Q86UL3,P11279,Q4J6C6,P51809,Q8N5M9,Q96PC5,P14174,O15126,P0DP25,P50416,P53985,O43760,Q32P28,P55327,Q86YV9,Q9Y2G5,Q7L0J3,Q9Y5X3,Q15758,Q9BRT2,Q99808,P49755,Q8NE86,P49841,P16220,Q5JRA6 50 +Mitochondrial calcium ion transmembrane transport 0.7352217128545424 2.140368807488892 0.0323249732867789 1.0 0.0963700380463562 9 Q9NWR8,O95202,Q8NE86,Q9BPX6,P21796,Q8IYU8 6 +Positive regulation of macroautophagy 0.5568508708822173 2.140337655550196 0.0323274889315738 1.0 0.0963700380463562 20 P09601,P21796,P27544 3 +Phosphatidic acid metabolic process 0.7560878790086218 2.134841931661075 0.0327739238679094 1.0 0.0973139379504611 5 Q9NPH0,Q9HCL2 2 +Atp synthesis coupled proton transport 0.6718416228546905 2.134808669696226 0.0327766418335189 1.0 0.0973139379504611 12 P36542,P24539,P00846,P56134,P06576,O75964 6 +Regulation of complement activation 0.6535543036798188 2.1315137523142553 0.0330468407053414 1.0 0.0977648031430625 3 Q99623 1 +Regulation of humoral immune response 0.6535543036798188 2.1315137523142553 0.0330468407053414 1.0 0.0977648031430625 3 Q99623 1 +Early endosome to golgi transport 0.7561122849614724 2.126224669365525 0.0334845569512773 1.0 0.0987503065109291 8 O15260,Q9BVK6,Q13190,O60499,O60749 5 +Regulation of membrane tubulation 0.5978100029594613 2.1238766253144212 0.0336804614462695 1.0 0.0991510778166572 2 Q9Y371 1 +B cell homeostasis 0.8001346444573327 2.1207449295204004 0.0339432733247828 1.0 0.0994959700659042 6 P00813,P49069 2 +Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules 0.6515095648515539 2.120508112606393 0.0339632181069269 1.0 0.0994959700659042 3 P98194 1 +Deoxyribonucleoside triphosphate catabolic process 0.7528183651550049 2.1193871753156426 0.0340577597405364 1.0 0.0997225084641292 5 P00813 1 +Establishment of pigment granule localization 0.6512729425695617 2.1192336549414397 0.0340707253914365 1.0 0.0997225084641292 3 Q15907,Q13561 2 +Energy derivation by oxidation of organic compounds 0.3603920357676032 2.1151609604290096 0.0344162310206777 1.0 0.1005645886617746 130 P56385,P14406,Q9UDW1,Q9BSK2,P20674,O43674,P00846,O75874,O43676,P06576,P06493,O75438,O75306,O75964,Q9H3K2,P00403,P43304,P31749,Q8NC60,P21912,P48735,O95168,O75208,O95298,Q9Y6M9,P13073,P04062,P14927,P24539,P31751,O14949,Q9BRT2,P46976,P36542,Q9NZ45,P09622,O75489,P03886,P22695,P49841,Q9H936,P15954,P10606,P10253,Q9NQ88,P22413,Q13423,P56134,O14548 49 +Cellular copper ion homeostasis 0.7054997778020017 2.1135738502786356 0.034551681265396 1.0 0.1005645886617746 4 O75880,P05067 2 +Copper ion homeostasis 0.7054997778020017 2.1135738502786356 0.034551681265396 1.0 0.1005645886617746 4 O75880,P05067 2 +Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.6497525635156199 2.1110405891289963 0.0347688232445604 1.0 0.1009194942745806 3 O43464 1 +Atp metabolic process 0.3659033834705255 2.1110290831904184 0.0347698121445332 1.0 0.1009194942745806 114 P56385,P14406,Q9UDW1,Q9BSK2,P20674,P05026,P00846,O75438,O43676,P06576,P06493,P52789,O75306,O75964,Q9H3K2,P00403,P05067,O95168,O75208,O95298,P13073,Q9BRR6,P14927,P24539,O14949,Q9UII2,P36542,P09622,O75489,P03886,P22695,P15954,P10606,Q9NQ88,P30536,P22413,P56134 37 +Sulfur compound transport 0.7287327484050381 2.107843575772377 0.0350445221902233 1.0 0.1015830031382395 9 Q70HW3,Q9UBX3 2 +Response to glucagon 0.6487700104211789 2.105741876224679 0.035226780158184 1.0 0.1019771309966878 3 P16220 1 +Adp transport 0.7038791827065382 2.105458380563573 0.0352514265256906 1.0 0.1020037994344526 4 P12235,P12236,O43808 3 +Negative regulation of transmembrane transport 0.5292314660115486 2.1048984271098465 0.035300150651218 1.0 0.1021000856253392 26 P31749,Q9UMX0,P21796,P46934,P31751,P22413,O95747,O75915,P0DP25 9 +Amyloid precursor protein metabolic process 0.5328536126450885 2.1004669744244335 0.0356877828334121 1.0 0.1029958763083059 25 P49755,O75298,O95197,P10909,Q9NQX7,Q9NQC3,Q15392,Q9Y287 8 +Membrane protein proteolysis 0.6515814273627654 2.093169932677635 0.0363339877581572 1.0 0.1045732575434997 13 Q8TCT8,Q92542,Q16740,Q8TCT9,Q9Y4W6,P78536,P38159,Q9NZ08 8 +Regulation of long term synaptic potentiation 0.7719196616475552 2.0927070724706316 0.0363753115318901 1.0 0.104614636168086 7 Q9BPZ3,Q92542,Q13501,Q99538,P05067 5 +Regulation of transport 0.324681345967658 2.091366526506418 0.0364952204166766 1.0 0.1048999099242894 347 P00813,Q15907,P50897,Q00765,P05023,Q96PU5,P21796,P16615,O15260,P09601,Q9Y282,P11279,P49257,P51809,P14174,P50416,Q07812,Q9Y2G5,O75844,Q8WTV0,Q9P2W9,Q9Y3B8,Q9C0E2,P16220,P57105,P30536,Q9BWF3,O14737,P05026,Q16850,P55786,P06493,P52789,Q7Z4L5,Q5T9L3,Q96KC8,Q8N183,Q9BZL1,Q15041,P51151,P05067,Q13438,P18031,P60604,O75298,P62258,O76024,O43464,Q9UII2,Q9BRT2,Q12907,P51148,P61020,Q13263,Q8NE86,P49841,Q9Y263,Q9P253,P27361,Q8NBU5,Q99623,Q9GZP9,O95429,P30533,P27105,Q07666,P33176,Q15019,P20339,Q9UNH7,O14980,P54709,Q8N5M9,P50402,Q14C86,P53985,Q32P28,O95563,P31751,Q6IAA8,P10909,Q4KMQ2,Q08722,Q7L0J3,Q9Y5X3,O43865,Q8N6T3,Q9NR31,P49755,P22413,P08183,Q92544,Q9UMX0,P61978,P46934,O43768,P51572,Q9H4A5,P31749,O43633,Q9GZY8,Q9H4A6,Q4J6C6,P0DP25,Q08J23,P98194,Q16625,P0CG08,Q9H223,O75915,O95747 111 +Nonribosomal peptide biosynthetic process 0.7010440097333053 2.0912434302665472 0.03650624796881 1.0 0.1048999099242894 4 Q99735 1 +Carbohydrate derivative biosynthetic process 0.3515167384811821 2.0883449965544334 0.0367667252563934 1.0 0.1055521485792789 168 P56385,P00813,Q8TCJ2,P50897,O60762,Q8TB61,Q13232,Q9H9S5,P00846,Q9BT22,Q16739,Q9NQX7,P06576,O75964,Q8WVC6,P00403,O15118,Q8WVQ1,Q9H4A6,O43505,O60476,Q9BXS4,Q9UMR5,Q9UKU0,Q9Y287,Q10472,P33908,Q16880,P24539,Q13126,Q8NCH0,Q8NBX0,O14734,Q7LGA3,Q9Y2G5,Q9H0U3,Q8NBZ7,P46977,P36542,Q53GQ0,Q86YN1,P09622,Q92542,Q99805,O60502,Q9HC07,O43292,P06865,P56134,P04843,Q06203 51 +Regulation of autophagy of mitochondrion 0.6238724098011525 2.0881850356919713 0.0367811466451928 1.0 0.1055521485792789 15 P30536,P21796,P27544 3 +Outer mitochondrial membrane organization 0.7455278030625899 2.084831350055478 0.0370846119264789 1.0 0.1061924611014295 5 Q9NS69 1 +Oligosaccharide catabolic process 0.6445490188430529 2.082944140780115 0.0372563154894105 1.0 0.1066379337676545 3 P17900 1 +Regulation of hormone metabolic process 0.7449287214327509 2.0819860733571676 0.0373437418169948 1.0 0.1068007875841647 5 O75844,P16435 2 +Protein insertion into er membrane 0.649580417884004 2.081637359802685 0.0373756062194754 1.0 0.1068007875841647 13 Q15629,P46379,P49069,Q9NPA0,O43681,Q96A33 6 +Copi coated vesicle budding 0.7448501403382838 2.081612795882977 0.0373778516692651 1.0 0.1068007875841647 5 Q15363,Q9BVK6 2 +Regulation of hormone levels 0.3956156263492683 2.075780343012455 0.0379142712013018 1.0 0.1081931858244404 70 Q15907,Q9Y394,P05023,P07858,P42892,O43768,Q9HB40,Q8N183,P16435,P51809,Q14849,Q8N5M9,Q8NBQ5,P50416,P53985,Q8NBN7,O75844,Q9BRT2,Q53GQ0,O95470,Q6NUM9,P16220,P30536 23 +N glycan processing 0.743450999259169 2.0749640600847696 0.0379898658027837 1.0 0.1083380756293207 5 P33908 1 +Response to food 0.789933827533671 2.074878140463532 0.0379978301269126 1.0 0.1083380756293207 6 P80303,P53985,Q9UMX5 3 +Regulation of glycoprotein metabolic process 0.621406708414805 2.0731518838549414 0.0381581467020446 1.0 0.108701375669747 15 Q92542,Q99805,O14734,Q9H0U4,Q9NQX7,Q9BXS4,Q9Y287 7 +Glial cell proliferation 0.7447971653959304 2.071527260661273 0.0383095496096121 1.0 0.1090856584963063 8 P30536,Q96G23,P04062 3 +Collagen metabolic process 0.672211331370209 2.0679931642502987 0.038640665892428 1.0 0.1097819535241563 11 P08670,P07858,Q92791,Q9UBG0 4 +Sterol transport 0.5201304003456617 2.0678540881795744 0.0386537457785916 1.0 0.1097819535241563 27 O15118,Q96JX3,P61916,P30536,Q14849,Q8WTV0 6 +C21 steroid hormone metabolic process 0.6958495765423715 2.0651429218868715 0.038909479256677 1.0 0.1100876134979043 4 Q14849 1 +Regulation of release of cytochrome c from mitochondria 0.6331947404585662 2.0626434520676504 0.0391465161668871 1.0 0.1104222472671605 14 O60313,P31749,O14737,Q96A26,Q9GZY8,P10909,Q9H3K2 7 +Negative regulation of amyloid fibril formation 0.7870605609606022 2.061917883298342 0.0392155546309345 1.0 0.1104755330587579 6 P10909,O15212 2 +Regulation of synapse structural plasticity 0.5871559633027584 2.0615757616123087 0.0392481436425371 1.0 0.1105202306491384 2 Q14012 1 +Electron transport chain 0.3884377638307669 2.0612282672703657 0.0392812679677718 1.0 0.1105663969331364 72 O43674,Q9UDW1,P20674,O75438,P06493,O43676,O75306,Q9H3K2,P00403,P43304,P16435,O43175,P21912,O95168,O75208,O95298,Q9Y6M9,P13073,P04062,P14927,O75746,O14949,P56556,P09622,O15460,O75489,P03886,Q9H936,P15954,P10606,O14548 31 +Positive regulation of protein exit from endoplasmic reticulum 0.7405213270142128 2.061026855402556 0.0393004780862811 1.0 0.1105733757651051 5 Q92544,Q9NR31,Q9Y6B6,P51572 4 +Positive regulation of fatty acid metabolic process 0.6948401832563198 2.0600625202028304 0.0393925643253934 1.0 0.1107040298435982 4 P50416,P31751 2 +Proton transporting two sector atpase complex assembly 0.7866215432484559 2.059936054703189 0.039404654337406 1.0 0.1107040298435982 6 Q92544,Q8N511,Q9BUB7 3 +Regulation of b cell differentiation 0.5868600177567389 2.0598391789470596 0.0394139177215897 1.0 0.1107040298435982 2 Q5JVF3 1 +Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.6393912317238872 2.0550104025942293 0.0398779999602265 1.0 0.1117191334213144 3 Q9BRG1 1 +Neuron recognition 0.785494933824979 2.0548483622884826 0.0398936533324711 1.0 0.1117191334213144 6 P35613,P05067 2 +Antigen processing and presentation of exogenous peptide antigen 0.7391648165759674 2.054566552897601 0.0399208890215956 1.0 0.1117480540210612 5 Q99538,Q9UIQ6,P04439 3 +Cellular sodium ion homeostasis 0.7390402843601853 2.053973252604311 0.0399782805638802 1.0 0.1118139891014371 5 P05026,P05023,P54709,Q96PU5 4 +Chloride transmembrane transport 0.7390402843601815 2.0539732526042926 0.0399782805638819 1.0 0.1118139891014371 5 Q4KMQ2,P51798,Q9UHG3,P51790 4 +Protein localization to organelle 0.3203508168725535 2.053479320357963 0.0400261133451378 1.0 0.1118854451643683 356 O60830,Q9NS69,P24390,Q14108,P49069,Q99595,O43731,O00571,Q8N4H5,P11279,O43615,P49257,Q9Y5Y5,Q15629,Q9Y5L4,Q9Y512,P33908,Q5J8M3,Q07812,O95831,O14773,P13473,O94901,Q9Y5M8,P30536,O14925,O14737,Q8TD16,O96008,Q96C92,P40616,P55786,P06493,O15027,P52789,Q9BV73,Q7Z4L5,Q9BZL1,Q5JRX3,Q13438,Q9UK61,Q9Y5J9,Q8NEY8,O75116,P62258,P61009,Q9NQC3,O43464,O60220,Q9UII2,Q96A33,Q13263,Q8N8Q8,P67809,P49841,Q5JRA6,Q10713,O43292,Q15388,Q9P0I2,Q9NWS0,Q99623,Q96D46,O95429,Q96HY6,Q9UGP8,P40855,Q9Y6C9,Q9NPA0,Q92973,P10909,Q3ZCQ8,P49755,Q8N1F7,O75381,O15258,Q9BRG1,P46934,P51572,P31749,Q9GZY8,Q9H4A6,Q99442,Q9Y5J7,P0DP25,Q8WXW3,Q15555,P46379,P31483,Q13501,O43681,Q9UHB9,Q9P2S5 93 +Leukocyte homeostasis 0.6181664609925255 2.053359876472825 0.0400376876704087 1.0 0.1118854451643683 15 P00813,P31749,P49069,Q9HCL2,Q07812,P14174 6 +Negative regulation of steroid metabolic process 0.6385435168738804 2.0504113102861723 0.0403243104111494 1.0 0.1124740152462987 3 P05023,O75477 2 +T cell differentiation 0.5262426541194675 2.050012947761375 0.0403631673333499 1.0 0.1125095625922016 25 P00813,P24390,P04062 3 +Inorganic anion transmembrane transport 0.716646699249756 2.0469585185371204 0.0406621575974253 1.0 0.1130093353916668 9 Q02978,Q9UBX3,Q4KMQ2,P51798,Q9UHG3,Q9Y289,P51790 7 +Mitophagy 0.6029959347951275 2.0452200708382957 0.0408331666021986 1.0 0.1132464952051744 16 P12235,Q99623,Q9Y4P1,P49815,P27544,P53365,Q13501,Q16543,P21796,Q9NQ88,O43464 11 +Adult behavior 0.5366632731205145 2.0436334529474443 0.0409897718831477 1.0 0.1135378886738154 22 O15118,P50897,Q92542,P05067,O75844,O43464,Q8N2K0 7 +Cdp diacylglycerol metabolic process 0.7362795249017059 2.040810745095599 0.041269642127705 1.0 0.1142652135827408 5 Q9HCL2,Q86UL3 2 +Regulation of secretion 0.362819696591859 2.0398122266115695 0.0413690315769468 1.0 0.1143829784816552 102 P00813,Q16850,O43768,Q9H4A5,P16615,Q5T9L3,O43633,Q96KC8,Q8N183,P09601,P20339,P51151,Q9H4A6,P11279,Q4J6C6,P51809,Q8N5M9,P14174,P0DP25,P50416,P53985,Q32P28,Q9Y2G5,Q7L0J3,Q9Y5X3,Q9BRT2,P49755,Q8NE86,P49841,P16220 30 +Cerebellar purkinje cell layer morphogenesis 0.7360615172769895 2.0397705646790794 0.0413731828788666 1.0 0.1143829784816552 5 Q15058,P04062 2 +Regulation of cellular response to osmotic stress 0.6907336631955308 2.0393654867184905 0.0414135642814583 1.0 0.114424016026822 4 O95202 1 +Regulation of leukocyte migration 0.4939956530855915 2.0334278952814437 0.0420093114579875 1.0 0.1157796244478064 31 P00813,P31749,P09601,Q8NE86,Q99538,P05067,Q5JRA6,Q08722,O95747,P78536,P14174 11 +Vitamin transport 0.7136315579345917 2.0317078004789084 0.0421832457666158 1.0 0.1159688316437453 9 Q8WTV0,Q9H2D1,P04062 3 +Membrane protein ectodomain proteolysis 0.6654607466705516 2.0308977535097723 0.0422653677282673 1.0 0.1161462849547273 11 Q8TCT8,Q92542,Q8TCT9,P38159,Q9NZ08 5 +Lymphocyte homeostasis 0.6523408162314148 2.02525182137301 0.0428415129208721 1.0 0.117339228716968 12 P00813,P14174,P49069 3 +Calcium import into the mitochondrion 0.7783703703703452 2.022610679494264 0.0431133022732597 1.0 0.1179370094056181 6 Q9NWR8,Q8NE86,Q9BPX6,P21796,Q8IYU8 5 +Positive regulation of mitochondrial membrane potential 0.7324052643413244 2.022308438254973 0.0431444974293602 1.0 0.117973514071428 5 Q8IWA4,P31751 2 +Apoptotic mitochondrial changes 0.4868786910631469 2.0218356932272568 0.0431933290050425 1.0 0.1180581932979017 32 O60313,P31749,P12235,Q9UII2,P45880,O14737,Q9Y3B8,Q96A26,Q9GZY8,P10909,Q07812,Q3ZCQ8,P52789,Q9H3K2 14 +Positive regulation of dna damage response signal transduction by p53 class mediator 0.6331544031782648 2.0211212151564486 0.0432672187055713 1.0 0.1182067086965271 3 O43324 1 +Response to endoplasmic reticulum stress 0.3843936420609062 2.0209645301328036 0.0432834369867749 1.0 0.1182067086965271 89 Q8TCJ2,Q9UBV2,Q9GZP9,Q9UMX0,P57088,Q9BS26,Q92905,Q96HY6,O00571,O15027,O95881,P51572,P16615,Q5VYK3,Q9BUN8,Q13438,P18031,P60604,O60313,P07237,P33908,Q8TCT9,Q96JB5,P10909,Q15363,Q07812,Q9Y4P3,O95831,O76024,Q96A33,Q9H3N1,P46379,P49841,P05198 34 +Neurotransmitter secretion 0.5368207203174618 2.019986158065521 0.043384823339827 1.0 0.118434654049119 21 P16615,Q13277,P50897,O95721,P20339,P49841,Q7L0J3,Q4J6C6,P0DP25 9 +Long term synaptic potentiation 0.6624296803501937 2.0141944844470885 0.0439891185494876 1.0 0.1195411531634719 11 Q9BPZ3,Q13277,Q92542,Q13501,Q99538,P05067,Q14168 7 +Regulation of anion transport 0.6247489400860425 2.0123573522057794 0.0441822807369094 1.0 0.1200167256022336 14 Q15041,O75915,Q7L0J3,P08183,P14174 5 +Alcohol biosynthetic process 0.4782501303331013 2.0108827936413385 0.0443378382014301 1.0 0.1203403583873723 34 P16435,P04062,Q14739,Q15125,P00374,O75845,O15269,Q16850,Q15800,Q13510,Q15392 11 +Branching involved in mammary gland duct morphogenesis 0.6310435354460188 2.0096238407088647 0.0444710160306667 1.0 0.1206522762506881 3 Q9Y297 1 +Mitochondrial electron transport cytochrome c to oxygen 0.7751111111110836 2.0078264700829607 0.044661734964466 1.0 0.1210087471982961 6 P13073,P20674,P15954,P10606,P00403 5 +Negative regulation of intrinsic apoptotic signaling pathway 0.4778437713529535 2.0073113944440477 0.0447165166500549 1.0 0.1210698314380225 34 O60313,P31749,Q9UL15,Q8N2F6,P45880,O75489,Q07820,O43464,Q96K76,P10909,O00571,P18031,O95881,Q15233,P14174 15 +Regulation of multicellular organism growth 0.5969428056284228 2.00699597762894 0.0447500912788692 1.0 0.1211111192719273 16 O95470,Q99538,Q9HCL2,Q86UL3,P05067,O75844,O43464 7 +Positive regulation of leukocyte proliferation 0.568183489073284 2.005575827485915 0.0449015230578393 1.0 0.1214712099423905 18 P00813,P14174,Q9HCL2 3 +Nervous system process 0.3590166513145503 2.00446294891801 0.045020492024125 1.0 0.1216934281339233 114 P07196,P50897,Q05086,Q14108,P17900,Q9BV73,Q9BPZ3,P31749,O43251,O00264,P53634,Q99538,Q6P4Q7,P07686,P05067,Q9Y5J7,O75569,Q14168,Q9Y5J9,O75116,O43924,O60313,Q9Y5L4,P04062,Q9H0U3,O75844,O76024,O14773,Q9UQB8,Q15555,Q99808,Q92542,P49841,P16220,P10253,O75915,Q9H6K4,P27361 38 +Lipoprotein localization 0.727006977538357 1.996467833373865 0.0458830236614018 1.0 0.1237717972972264 5 Q5JRA6,A6NIH7,O15260 3 +Collagen biosynthetic process 0.7268759249117328 1.9958396430000784 0.0459513801907465 1.0 0.1238856345235825 5 Q92791 1 +Regulation of necrotic cell death 0.658930058891734 1.9948729805207552 0.046056735101573 1.0 0.1238921769155094 11 Q13510,P00403 2 +Anatomical structure maturation 0.4781230577287605 1.9948534019533604 0.0460588710366782 1.0 0.1238921769155094 33 Q08J23,P09622,P04062,Q9NZJ7,Q15125,Q86UL3,P05067,Q8N2A8,Q8IXJ6,O75503,Q9Y2W6 11 +Regulation of mitochondrial gene expression 0.658880976134373 1.9946017182960725 0.0460863360405114 1.0 0.1239156203790644 11 Q9Y2R0 1 +Negative regulation of interferon gamma production 0.5753181414619774 1.9918616397114088 0.046386240871358 1.0 0.1245193606493928 2 P09429 1 +Entry into host 0.4741679952445785 1.9907537404913664 0.0465079673497346 1.0 0.1247434808887911 35 Q14108,P07858,P35613,Q9BTY2,Q8WTV0 5 +Steroid biosynthetic process 0.4555553935810749 1.9839197333500544 0.047264788687239 1.0 0.126260313423099 45 Q53GQ0,P05023,P16435,Q14739,Q15125,O75845,Q16850,Q9H3P7,O14734,P30536,Q15800,Q14849,P28288,Q13510,Q15392,Q14534 16 +Lung alveolus development 0.769652972034656 1.983016958266133 0.0473655353275495 1.0 0.1263782087120608 6 P00813,O60476 2 +Protein processing 0.4524546377427688 1.981594602876556 0.0475246317250253 1.0 0.1267003997864833 46 P42892,Q9H9S5,Q99538,Q5JRX3,Q9BXS4,Q9UG56,P67812,Q8TCT9,Q92896,P61009,O75844,O75503,O43464,Q15392,O75976,Q92542,Q9Y4W6,Q10713,P78536 19 +Negative regulation of proteolysis 0.3821854613678381 1.98089278578819 0.04760329829061 1.0 0.1268589509688072 72 P31749,Q9UL15,P46379,P49755,Q96KC8,P49069,P16435,P78318,P07858,Q15041,Q9Y3B8,P05067,Q96K76,Q92896,Q96HY6,Q9H2J4,O00571,Q15392 18 +O glycan processing 0.7232077750398369 1.9782400732628025 0.0479016299649206 1.0 0.1276025281895044 5 O43505,Q10471,Q10472 3 +Maternal placenta development 0.744882043568872 1.9658413757454416 0.0493169366842143 1.0 0.1309504357356257 7 Q15363,P07858,P35613 3 +Regulation of dna catabolic process 0.6226541324279085 1.963792376025695 0.0495541745951741 1.0 0.1314747249696934 3 O95831 1 +Regulation of apoptotic dna fragmentation 0.6226541324279085 1.963792376025695 0.0495541745951741 1.0 0.1314747249696934 3 O95831 1 +Cerebellar purkinje cell layer development 0.7002062630106376 1.9635063594474944 0.0495873662675452 1.0 0.131509993443903 9 P54802,P04062 2 +Regulation of defense response to virus 0.6033790256464968 1.962512061854208 0.0497028977116009 1.0 0.131690092113258 15 O43657 1 +Cristae formation 0.7224347216736308 1.962486041772528 0.0497059241182624 1.0 0.131690092113258 8 Q9Y512,O95202,Q9Y4W6,Q5XKP0,Q6UXV4,Q9NX63 6 +Glycosylceramide metabolic process 0.7650919212308553 1.962236312913384 0.049734978047313 1.0 0.131690092113258 6 Q16739,P04062 2 +Regulation of organic acid transport 0.6409957904852945 1.960929748999554 0.0498872184487571 1.0 0.1320402990499942 12 P31749,Q15041,P31751,Q7L0J3,P14174 5 +Regulation of proteolysis 0.3439300775353178 1.9591527272107232 0.0500949034019571 1.0 0.1325369161663468 174 Q05086,Q9UMX0,P49069,O14737,P07858,Q15375,Q96HY6,O00571,Q9H2J4,P61289,P51572,Q9BW61,P31749,Q9UL15,P78318,P53634,Q96KC8,P16435,Q15041,Q99538,P05067,Q96K76,Q9Y297,Q9BXK5,P04062,Q96A26,Q9UL46,P24941,P10909,Q92896,O95831,O43464,Q15392,Q9NR28,P49755,Q92542,P46379,Q9NZJ7,Q9Y3B8,O75915,Q9UBS8 41 +Endosomal transport 0.3841386858395439 1.9589785623967468 0.0501152974196659 1.0 0.1325378153847827 87 Q15907,Q9BRG1,O15498,Q13190,Q567U6,Q96L92,O43633,O15260,Q2M389,Q4J6C6,O60749,O43752,Q9BVK6,Q96D71,Q9Y5X3,O75503,Q13501,O60499,Q9H223,O95249 20 +Complement activation 0.6746535980237413 1.95788586104034 0.0502434073392785 1.0 0.1327703634967181 4 P10909,Q99623 2 +Lipoprotein biosynthetic process 0.6400627664076523 1.9556209110257512 0.050509827686501 1.0 0.1332782102793233 12 O60762,O43292,Q16739,P04062 4 +Nucleoside triphosphate catabolic process 0.7633733191268466 1.9543947120546352 0.0506545555895459 1.0 0.1334793623326528 6 P00813,Q9H773 2 +Intraciliary transport involved in cilium assembly 0.6207770255787739 1.9535080448239308 0.0507594249609995 1.0 0.133649677839932 3 Q15154 1 +Regulation of ire1 mediated unfolded protein response 0.7630742553080769 1.9530295110791775 0.0508160984165542 1.0 0.133649677839932 6 Q92905,Q07812,Q96HY6,P57088 4 +Cellular response to zinc ion 0.6206890228090258 1.953025628831523 0.0508165584135047 1.0 0.133649677839932 3 P30536 1 +Positive regulation of protein localization to centrosome 0.6736949303193174 1.9530064667113587 0.0508188289320243 1.0 0.133649677839932 4 P49841,Q9BV73 2 +Maternal process involved in female pregnancy 0.6389185089451266 1.9491062642336576 0.0512827357476839 1.0 0.1347034874018603 12 Q15363,P07858,P35613,Q9BQE5 4 +Plasma membrane to endosome transport 0.6728988667712099 1.9489528493760035 0.0513010558012532 1.0 0.1347034874018603 4 P61020 1 +Organelle disassembly 0.4399450551871913 1.9484187472446872 0.0513648784158402 1.0 0.1347576516122147 49 Q99623,Q13190,Q16543,P21796,Q9BWH2,Q96HY6,P06493,P52789,Q7Z3C6,P41214,P27544,P53365,Q9Y6I9,P04062,O43464,Q9UII2,P12235,Q13501,Q9NQ88,P30536 20 +Tetrahydrobiopterin metabolic process 0.6198146205538102 1.9482310210960485 0.0513873265605329 1.0 0.1347576516122147 3 P00374 1 +Hormone biosynthetic process 0.6969874827134113 1.9470834974654332 0.0515247251255166 1.0 0.1349690480993022 9 Q53GQ0,P05023,P16435,P30536,Q14849 5 +Regulation of membrane depolarization during action potential 0.5673276117194501 1.9445166299111365 0.0518331820030049 1.0 0.1354013833430274 2 Q12955 1 +Regulation of membrane depolarization during cardiac muscle cell action potential 0.5673276117194501 1.9445166299111365 0.0518331820030049 1.0 0.1354013833430274 2 Q12955 1 +Membrane depolarization during cardiac muscle cell action potential 0.5673276117194501 1.9445166299111365 0.0518331820030049 1.0 0.1354013833430274 2 Q12955 1 +Peptidyl proline hydroxylation 0.7184824319026016 1.943086012128669 0.052005766808576 1.0 0.1356913197149147 8 P13674,O75718,Q32P28,O15460,Q8IVL6 5 +Positive regulation of intracellular protein transport 0.4161592796061608 1.940515321343639 0.0523170940011488 1.0 0.1363959267272554 57 Q92544,Q9NR31,Q13263,O14737,Q9BZL1,Q9Y3B8,Q9GZY8,P62258,Q9C0E2,Q9Y282,P31751,P55786,P06493,P50402,O43464,P51572,P27105 17 +Proteolysis 0.2981957011964189 1.9375944497807336 0.0526727201498669 1.0 0.1369449281945202 406 Q05086,P49069,Q96PU5,Q16740,P30260,Q15375,O00571,P61289,Q9HB40,Q9BW61,Q9BWJ5,P78318,P53634,Q99538,Q9BXS4,P83111,P04062,Q99627,Q96A26,P67812,P33908,Q8TCT9,Q9UHG3,Q07812,O95831,Q96FZ2,O75844,O75503,O14773,Q9BT78,O75976,P09622,Q9Y3B8,P22695,O43242,Q8IXJ6,P78536,P42785,P10619,O14737,P07858,P42892,P55786,Q9UL15,Q96KC8,Q15041,P05067,Q96K76,Q9BUN8,Q9UJX3,Q9UIQ6,O43464,P28072,Q96A33,Q8TCT8,Q9NR28,Q10713,O43292,Q9H3G5,Q9UBS8,Q9UBV2,Q9GZP9,P28074,O00231,Q92905,Q9H9S5,Q96HY6,Q6P179,Q9Y297,P38159,Q9UG56,P24941,P10909,Q15392,P49755,Q92542,Q9NZJ7,Q9BRG1,Q9UMX0,P46934,Q9H2J4,P51572,P31749,O43633,P16435,P36551,Q4J6C6,Q9NZ08,Q9BXK5,Q9UL46,Q92896,P46379,Q13501,O75915 94 +Negative regulation of potassium ion transmembrane transport 0.714623309521099 1.936927837318772 0.0527541650882843 1.0 0.1370488510489274 5 O95747 1 +Negative regulation of potassium ion transport 0.714623309521099 1.936927837318772 0.0527541650882843 1.0 0.1370488510489274 5 O95747 1 +Peptidyl proline hydroxylation to 4 hydroxy l proline 0.7144596849423451 1.936138719947546 0.0528507133706237 1.0 0.1372376029372468 5 P13674 1 +Er overload response 0.7144298207142946 1.9359946860353456 0.0528683518048465 1.0 0.1372376029372468 5 Q96A33,O76024 2 +Positive regulation of leukocyte migration 0.5431221619162379 1.9344472202626817 0.0530581654429997 1.0 0.1375131910842918 19 Q8NE86,Q99538,P05067,Q5JRA6,Q08722,O95747,P78536,P27361 8 +Endoplasmic reticulum to cytosol transport 0.6107877659910244 1.9286550082105651 0.053773705195153 1.0 0.1388364639399765 14 Q9UBV2,Q9GZP9,Q8TCT9,Q9BUN8,Q13438,P51572 6 +Antigen processing and presentation of peptide antigen 0.6106654651313309 1.9279186175276743 0.0538652496307621 1.0 0.1390016983460629 14 P04439,Q6P179,P10321,P01889,Q9UIQ6,Q9NZ08 6 +Regulation of notch signaling pathway 0.7569649387616642 1.9250996992502225 0.054216886589872 1.0 0.139695673868407 6 P57105 1 +Mitochondrial cytochrome c oxidase assembly 0.735701252763518 1.9223821865193345 0.0545576853560201 1.0 0.1403205588116354 7 Q9Y2R0,Q8N8Q8 2 +Respiratory chain complex iv assembly 0.735701252763518 1.9223821865193345 0.0545576853560201 1.0 0.1403205588116354 7 Q9Y2R0,Q8N8Q8 2 +Mitochondrial calcium ion homeostasis 0.668770033666201 1.9192780730110548 0.0549491514798383 1.0 0.1410318876739041 10 Q9NWR8,O95202,Q8NE86,Q9BPX6,Q8IYU8,P51572 6 +Proteoglycan metabolic process 0.713507293364619 1.918611208110331 0.0550335560803079 1.0 0.1411041755335729 8 Q99805,Q7LGA3,Q9NX62,Q8NCH0 4 +Regulation of b cell proliferation 0.7348939862414527 1.918551724632266 0.0550410901082691 1.0 0.1411041755335729 7 P00813 1 +Maintenance of protein location in cell 0.5123083819510773 1.9141723358780611 0.0555981392753484 1.0 0.1419814924539326 24 P31749,P24390,Q9H4A6,O43731,P30536,O43292,P52789,O94901,O15258 9 +Vesicle fusion to plasma membrane 0.613510801600092 1.9135965008320448 0.0556717325130142 1.0 0.1421145153258058 3 O95721 1 +Peptidyl glutamic acid modification 0.7097103172304866 1.913206546043104 0.0557216158378799 1.0 0.1421869340048449 5 Q8N0U8 1 +Negative regulation of lymphocyte apoptotic process 0.7542681971111412 1.912746134862373 0.0557805599293621 1.0 0.1422275156532231 6 P00813,P14174 2 +Negative regulation of leukocyte apoptotic process 0.7542681971111412 1.912746134862373 0.0557805599293621 1.0 0.1422275156532231 6 P00813,P14174 2 +Maintenance of location 0.3801581666511955 1.908023581117933 0.0563881685365614 1.0 0.1431142111590379 77 Q9H6V9,P31749,P24390,P04062,P17900,O95202,Q9H4A6,P10253,O43731,P30536,O43292,P22413,O95674,Q8WTV0,Q8NEW0,Q14534,O15258 17 +Proteoglycan biosynthetic process 0.7530521159846961 1.9071703912754845 0.0564985263214883 1.0 0.1432780514264741 6 Q99805,Q7LGA3,Q8NCH0 3 +Amino acid import 0.7110955856400586 1.906725442507274 0.0565561505226293 1.0 0.1433165582323745 8 Q96NB2,Q15041,P30825,O75915,Q9H9B4 5 +Protein trimerization 0.6645949689154814 1.9065697900052403 0.0565763202342661 1.0 0.1433165582323745 4 P14174,Q99720 2 +Positive regulation of lymphocyte chemotaxis 0.6116537940266095 1.9033708027440115 0.0569921780493234 1.0 0.1440387398577356 3 O95747 1 +Regulation of t cell chemotaxis 0.6116537940266095 1.9033708027440115 0.0569921780493234 1.0 0.1440387398577356 3 O95747 1 +Regulation of lymphocyte chemotaxis 0.6116537940266095 1.9033708027440115 0.0569921780493234 1.0 0.1440387398577356 3 O95747 1 +Regulation of monooxygenase activity 0.665710923523307 1.9029459300797789 0.0570476009176199 1.0 0.1441236981898128 10 P31749,P16435,P00374,Q8TCT9,Q8WTV0,P06280 6 +T cell mediated cytotoxicity 0.7101064761501307 1.9018467023661012 0.0571911986752304 1.0 0.1444312694094758 8 O15400,P53634,P04439,P01889,Q9NUQ9 5 +Signal release 0.399594728602714 1.8991847562214004 0.0575401882909916 1.0 0.1451462230592227 63 Q15907,Q13277,P50897,O43768,P16615,O95721,Q5T9L3,Q8N183,P20339,Q4J6C6,P51809,Q8N5M9,P14174,P0DP25,P50416,P53985,Q7L0J3,Q9BRT2,Q8NE86,P49841,P16220 21 +Water homeostasis 0.6634586291714966 1.8909043740646791 0.0586371104487633 1.0 0.14723885370664 10 Q9Y3B8,Q16739,P04062 3 +Macrophage differentiation 0.704902906228238 1.8899407621113404 0.0587658831287802 1.0 0.1473942017450128 5 P04062 1 +Reproductive behavior 0.7044665897496256 1.887826539201406 0.0590492410982916 1.0 0.1477125035649544 5 P05067 1 +Mating behavior 0.7044665897496256 1.887826539201406 0.0590492410982916 1.0 0.1477125035649544 5 P05067 1 +Regulation of potassium ion transmembrane transporter activity 0.6039686634406016 1.8875135344419631 0.0590912876748779 1.0 0.1477617556728218 14 Q96PU5,P05026,P62258,P46934,O95747,P54709,Q13642 7 +Regulation of steroid metabolic process 0.5911965203187284 1.887030008683153 0.0591562895353177 1.0 0.1478124451942966 15 P30536,Q13510,P16435 3 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.7039501421463458 1.885323465749075 0.0593861799052641 1.0 0.1482747499032455 5 Q9P0I2,Q5J8M3,Q9NPA0 3 +Homeostatic process 0.3234336066161272 1.8839973527736351 0.059565333547201 1.0 0.1486658947935996 312 P00813,Q15907,P50897,Q05086,P05023,P49069,Q96PU5,P30519,Q16739,O00571,P06576,Q8NE01,P16615,P62995,O15260,P09601,Q6P4Q7,O15254,P14174,Q9Y487,Q5BJF2,Q8N511,P04062,Q96TC7,Q93050,Q07812,O75503,O14773,Q8WTV0,P13473,P61421,Q99808,P09622,Q9Y3B8,O95202,P54105,Q9HD20,Q9HC07,P30536,P78536,P42785,P05026,P52789,Q9P0S9,Q8N183,Q15382,P07686,P05067,Q15067,P62258,Q9UKM9,Q9HCL2,Q9NQC3,Q9UIQ6,O76024,Q9H9B4,Q9UII2,Q96A33,Q9Y6M7,Q8NE86,Q9Y4W6,Q9Y263,P23786,Q8NEW0,O60826,P27361,Q9NWS0,O00767,Q9BPX6,Q9BS26,Q9NX40,O15118,P16949,O43251,Q9Y6C9,Q9P035,P61916,Q8N5M9,P53985,Q7L0J3,Q9Y5X3,Q92542,P10253,P22413,Q8IYU8,P51790,Q92544,Q9BWH2,P51572,P31749,O75880,P0DP25,Q9NWR8,P98194,Q86YV9,Q16625,P0CG08,Q15555,Q07820,Q13501,Q9UNW9 101 +Positive regulation of reactive oxygen species biosynthetic process 0.6599793479600901 1.882934248087795 0.0597092792135884 1.0 0.1487591127831846 4 P00403 1 +Positive regulation of bone mineralization 0.6598736678459702 1.8823924421181455 0.0597827513318411 1.0 0.1487591127831846 4 Q4KMQ2,O95747 2 +Positive regulation of biomineralization 0.6598736678459702 1.8823924421181455 0.0597827513318411 1.0 0.1487591127831846 4 Q4KMQ2,O95747 2 +Regulation of lymphocyte apoptotic process 0.6385568056881797 1.8816307320070216 0.0598861705651532 1.0 0.1489603693131718 11 P00813,P14174 2 +Associative learning 0.6270566830148934 1.8813211386723416 0.0599282471927493 1.0 0.1490089487196691 12 P50897,O00264 2 +Regulation of response to osmotic stress 0.7029340931541335 1.8803971797253165 0.0600539676426201 1.0 0.1492092752443897 5 O95202,Q9BPX6 2 +Regulation of glial cell proliferation 0.7027743459146486 1.879622434137679 0.0601595535569243 1.0 0.1493159979041903 5 P30536 1 +Negative regulation of inflammatory response 0.5898940191630292 1.8789261641874115 0.060254575723567 1.0 0.1493159979041903 15 P00813 1 +Reactive nitrogen species metabolic process 0.5493675040347887 1.8780288695921237 0.0603772158263238 1.0 0.1494821056554338 18 P31749,P16435,O43169,P10909,Q08722,P30536,P06280 7 +Myeloid leukocyte cytokine production 0.7052332994193715 1.8777757246932691 0.0604118524698402 1.0 0.1494821056554338 8 P09601 1 +Positive regulation of isotype switching to iga isotypes 0.5557857354246873 1.8757276803300849 0.0606926829627827 1.0 0.1500067096862495 2 P43246 1 +Regulation of cardiac muscle adaptation 0.555489789878669 1.8739577136968435 0.0609362536946991 1.0 0.1505524114647725 2 Q08209 1 +Acute inflammatory response 0.7007534659535992 1.8698164841914415 0.0615093064526748 1.0 0.1517979859394055 5 Q9BQE5 1 +Golgi vesicle budding 0.7032920126145358 1.8681709907405677 0.0617382409034992 1.0 0.1521357323382648 8 Q9H4A5,Q9BVK6,P49755,Q15363 4 +Oligosaccharide lipid intermediate biosynthetic process 0.7445262645283115 1.8679931443915787 0.061763026515279 1.0 0.152140082832456 6 Q96AA3,Q2TAA5,Q9BT22,Q86YN1 4 +Heparan sulfate proteoglycan biosynthetic process 0.6568246435465861 1.866748245185062 0.0619367529762913 1.0 0.152511177503841 4 Q7LGA3 1 +Response to uv a 0.6565510066093414 1.8653430846154488 0.0621333296396364 1.0 0.1528176167953014 4 P27544 1 +Negative regulation of ion transmembrane transport 0.5186703632536936 1.8651977378374056 0.0621536925322696 1.0 0.1528176167953014 20 Q9UMX0,P21796,P46934,O75915,O95747,P0DP25 6 +Leukocyte mediated cytotoxicity 0.5876413816080727 1.8648956164528736 0.0621960370082366 1.0 0.1528648600176406 15 O15400,P53634,P04439,P01889,P11279,Q9BY67,P51809,Q9NUQ9 8 +Positive regulation of proteolysis 0.3509283185849615 1.864690737729835 0.0622247658070942 1.0 0.1528786160665746 96 Q9UMX0,O14737,Q96HY6,O00571,P61289,P51572,Q9BW61,P31749,P53634,Q99538,P05067,Q9Y297,Q9BXK5,P04062,Q96A26,Q9UL46,P10909,Q07812,O95831,O43464,Q9NR28,P46379,Q92542,Q9NZJ7,O75915,Q9UBS8 26 +Ire1 mediated unfolded protein response 0.7224244576348465 1.8591995946537383 0.0629988522642075 1.0 0.1544932892816874 7 Q92905,Q07812,Q96HY6,P57088 4 +Calcium mediated signaling 0.5081727473066394 1.856140456601269 0.0634335405170614 1.0 0.1552934528558605 23 P00813,P16615,P05026,Q8NE86,O75844,P51572,P0DP25 7 +Lipid homeostasis 0.4934648382550286 1.8560766942288145 0.0634426271313093 1.0 0.1552934528558605 27 O15118,Q5BJF2,Q15067,Q9Y6C9,O15260,Q9HCL2,Q86YV9,Q9BWH2,P61916,O15254,Q9NQC3,Q8WTV0 12 +Negative regulation of neuron projection development 0.514288979196202 1.854473593524067 0.0636714346115701 1.0 0.1556805443388334 21 Q9UL15,Q9NR77,P08670,Q96G23,Q9NQX7 5 +Cellular response to chemical stress 0.3821433284725294 1.8518439311889243 0.0640482371866371 1.0 0.1563025735906578 84 Q9UMX0,Q8N0U8,P09493,Q9BPX6,Q86Y07,O00571,P06493,Q99720,P16615,Q9UL15,P31749,P09601,Q6NUK1,O75569,P04062,O95831,O43464,Q9NR28,Q07820,O95202,P00374,Q8IXJ6,P30536,O75915,P23246,O95747 26 +Vesicle docking 0.5590636947978673 1.8504391709268364 0.0642502777045681 1.0 0.1563849952052478 17 Q13277,O15400,O15498,Q13190,O60499,Q9P253,O43752 7 +Regulation of skeletal muscle cell differentiation 0.6535386437666496 1.8498616452318273 0.0643334931813632 1.0 0.1563849952052478 4 P17844,Q9BYT8,Q9BRT2 3 +Necrotic cell death 0.5719809665154809 1.847774403406536 0.0646349852819201 1.0 0.1569333643380639 16 Q13510,P00403 2 +Sterol biosynthetic process 0.5070476624701805 1.8475886289667716 0.0646618759255746 1.0 0.156940998160897 23 P16435,Q15125,O75845,Q16850,Q15800,Q15392,Q14534 7 +Neuromuscular process 0.4830095992395673 1.847067874310755 0.0647373037975118 1.0 0.1570663879580601 29 P07196,O43251,P04062,P05067,O75844,O14773,P17900 7 +Positive regulation of adaptive immune response 0.5583288528176763 1.8455684291059344 0.064954894104648 1.0 0.1575335476541542 17 P00813,O15400,P01889,Q96FZ2,Q9NUQ9 5 +Aminoglycan biosynthetic process 0.7192499574365883 1.8440349196257315 0.0651780513010169 1.0 0.1577881835342201 7 Q7LGA3,P06865,Q8NCH0 3 +Mitochondrial fusion 0.5966123300694369 1.8429435864975057 0.0653372475536862 1.0 0.1580151635312284 14 O60313,Q9Y6C9,Q9GZY8,Q8N2A8,Q07812,Q8IWA4,Q9NX63 7 +Ensheathment of neurons 0.4768928079906125 1.84112897842783 0.0656026599759294 1.0 0.1585205354358153 30 P31749,Q92542,Q9NR77,P53634,P35222,Q15058,P49770,O15228,Q16880,Q8N3R9,P07686,P31751,P10909,Q9Y4W6,Q8IXJ6,O75746,Q96P11 17 +Regulation of dna helicase activity 0.6002257977383562 1.8402159364421715 0.0657365412039094 1.0 0.1585637804001616 3 Q04837 1 +Nephron tubule epithelial cell differentiation 0.6001884208311767 1.8400087483821033 0.0657669529469742 1.0 0.1585637804001616 3 O95747 1 +Renal vesicle development 0.6001884208311767 1.8400087483821033 0.0657669529469742 1.0 0.1585637804001616 3 O95747 1 +Regulation of epithelial cell differentiation involved in kidney development 0.6001884208311767 1.8400087483821033 0.0657669529469742 1.0 0.1585637804001616 3 O95747 1 +Prostate gland development 0.7183803083203092 1.8398767464316113 0.0657863346735123 1.0 0.1585637804001616 7 P07602,Q9NZJ7 2 +Myelin maintenance 0.7383763078095604 1.839640735764759 0.0658209996392045 1.0 0.158589495667336 6 P10909,Q8N3R9,P31751 3 +Nucleotide transmembrane transport 0.6758130652963176 1.838373388710217 0.066007403642782 1.0 0.1586914989724068 9 Q9H2D1,P12236,Q8TB61,Q9BSK2,O43808 5 +Vesicle targeting 0.5023744692525478 1.8378376953502824 0.0660863252141352 1.0 0.1588234630328072 24 P49755,Q9BVK6,O15498,Q15363,O95772,Q14849,Q9NR31 7 +Nucleoside triphosphate metabolic process 0.4259623426720469 1.837318254250371 0.066162926640156 1.0 0.1589497572391097 50 O60313,P00813,P36542,Q9H773,P24539,P00846,Q8IWA4,P22413,P56134,O75964,P00403 11 +Cellular lipid metabolic process 0.3315139441335591 1.836150518099383 0.0663353985564767 1.0 0.1593061951525271 226 P50897,Q5T8D3,P48651,Q9BT22,Q16739,Q13011,Q9HB40,Q13510,Q9HBU6,P07602,O15254,Q9NPH0,O00116,P14174,P50416,P04062,Q8NHP8,Q16880,Q96JX3,O14734,Q07812,O75844,P28288,Q8WTV0,O95470,Q86YN1,P35790,Q8IXJ6,P06865,O60762,P51648,Q9Y394,Q9BWD1,Q9Y2B2,Q8IY17,P17900,Q92604,Q96AA3,O95864,P27544,Q8TBX8,Q15800,Q9UKU0,Q15067,Q8NBX0,Q9HCL2,Q96G23,P07099,O43464,Q8N2K0,P04066,Q10713,O43292,P06280,Q9UBV2,O15269,O75874,Q9P035,P61916,Q9UG56,Q9BVG9,Q99735,P31751,Q9NZJ7,Q99805,Q96N66,O43808,Q9NX62,P16278,P31749,P16435,Q86UL3,O95674,A1L0T0,Q8WXW3,Q53GQ0,Q6NUM9 77 +Response to thyroid hormone 0.7171996353591298 1.8342288023901536 0.0666200376763208 1.0 0.1598735762537416 7 P04062 1 +Regulation of fatty acid transport 0.6929846094217198 1.8320331261494744 0.0669464854297501 1.0 0.1604472199470072 5 P14174,P31751 2 +Positive regulation of programmed necrotic cell death 0.5480911512281808 1.8296103975036049 0.0673082178559369 1.0 0.161173917322423 2 Q9NZI8 1 +Adult locomotory behavior 0.5688719504802826 1.8277667813923597 0.0675845606770886 1.0 0.1616014332542976 16 O15118,P50897,P05067,O75844,O43464,Q8N2K0 6 +C4 dicarboxylate transport 0.6735513670285238 1.8266937301255908 0.0677458314991139 1.0 0.1619284630660557 9 Q02978,Q9UBX3,Q9H936,O75746,Q9UJS0,P55011,Q15758 7 +Histone h3 k4 demethylation trimethyl h3 k4 specific 0.5474992601361417 1.826054527487926 0.0678420487802264 1.0 0.1619913715146275 2 Q9H6W3 1 +Regulation of rna splicing 0.3588035936793152 1.8244215858754245 0.0680883610849611 1.0 0.162512090433553 93 Q9BWF3,P98179,Q15287,P26368,P61978,Q07955,P55795,Q16629,P35637,Q07666,P62995,P22626,O43251,P31943,P38159,Q96QD8,Q5BKZ1,P49736,Q13595,P98175,Q14011,P52597,P31483,Q96E39,P31942,Q9UHX1,Q9UNW9,P52756,O75525 29 +Negative regulation of secretion 0.5405120460539397 1.8174376154272127 0.0691501324746244 1.0 0.1645535618496776 18 P09601,P00813,Q16850 3 +Atrial septum morphogenesis 0.5460195324060438 1.8171596663432623 0.0691926688425259 1.0 0.1645535618496776 2 O96028 1 +Cardiac atrium development 0.5460195324060438 1.8171596663432623 0.0691926688425259 1.0 0.1645535618496776 2 O96028 1 +Cardiac atrium morphogenesis 0.5460195324060438 1.8171596663432623 0.0691926688425259 1.0 0.1645535618496776 2 O96028 1 +Atrial septum development 0.5460195324060438 1.8171596663432623 0.0691926688425259 1.0 0.1645535618496776 2 O96028 1 +Maintenance of protein location in mitochondrion 0.6471354173056698 1.8168775879297632 0.0692358591196629 1.0 0.1645970478136158 4 P31749,P30536 2 +Response to manganese ion 0.7329112953726555 1.814381784655277 0.0696189681313881 1.0 0.1653294144377808 6 P30536 1 +Lipopolysaccharide mediated signaling pathway 0.6709758881883798 1.813377984413848 0.0697735427492849 1.0 0.1655180703625355 9 P31749,Q8WTV0,P14174 3 +Protein targeting to peroxisome 0.6919586586540125 1.811920737272758 0.0699984446728676 1.0 0.1657318869565661 8 Q9Y5Y5,P40855 2 +Epidermis morphogenesis 0.5451316957679856 1.8118192056593785 0.0700141365384676 1.0 0.1657318869565661 2 P35222 1 +Positive regulation of endocytic recycling 0.5448357502219658 1.8100384632904123 0.0702898226507868 1.0 0.1661464370168277 2 Q9H4M9 1 +Chaperone mediated autophagy 0.6910073556294362 1.807185566250316 0.07073335066671 1.0 0.1670764597935543 8 P10619,P10909,Q05639 3 +Intermembrane lipid transfer 0.6906541311275662 1.8054268375262208 0.0710079146715729 1.0 0.1676639185653539 8 P30536,Q14849 2 +Amyloid fibril formation 0.6694017872278946 1.8052313821531965 0.0710384820732341 1.0 0.1676761885792873 9 P10909,O15212,P05067 3 +Positive regulation of amyloid beta formation 0.5935081257383723 1.8029135186532343 0.0714017975664464 1.0 0.1684735737653141 3 P10909 1 +Negative regulation of peptidyl threonine phosphorylation 0.5930962698134314 1.8006223143537778 0.07176242961394 1.0 0.1692640604277409 3 P0DP25 1 +Alpha linolenic acid metabolic process 0.6436301745707521 1.7987782707196018 0.072053761890533 1.0 0.1697089495133759 4 O14734,O95864 2 +Cellular iron ion homeostasis 0.600874170971994 1.7966218613518097 0.0723956713979308 1.0 0.1700899368179611 13 P09601,Q9Y487 2 +Positive regulation of monocyte chemotaxis 0.6431744151613784 1.7964227322516406 0.0724273111981448 1.0 0.1701038023129137 4 Q4KMQ2,Q99538,Q8NHP6 3 +Maintenance of protein localization in organelle 0.5372946919705971 1.7953362328077298 0.0726001455248919 1.0 0.1703281369449807 18 P31749,P24390,O43731,P30536,O43292,P52789,O94901,O15258 8 +Phospholipid transport 0.5371055964468505 1.7940358193995076 0.0728074518098 1.0 0.1706327833372229 18 Q8WTV0,P61916,Q14108 3 +Cellular transition metal ion homeostasis 0.5087674778989837 1.7925725384538775 0.0730413007430514 1.0 0.1711201547716509 20 Q8N511,P09601,P05067,Q8NEW0,Q9Y487 5 +Peptide catabolic process 0.6224282996132577 1.7910819892158352 0.0732801389411927 1.0 0.1716188654366914 11 Q6P179,P42892,Q9UIQ6,P55786,O14773 5 +Atp biosynthetic process 0.5078480272153678 1.785803930658277 0.0741310100856238 1.0 0.1733045085447074 20 P36542,P24539,P00846,P56134,O75964,P00403 6 +Regulation of defense response 0.3491062816066024 1.7843703748514987 0.0743635016583705 1.0 0.1736739056941237 95 P00813,Q16543,P01889,O43657,Q7Z739,P53634,P04439,Q9H1D9,Q8WXF1,Q9UNH7,P05067,P11279,P51809,P18031,Q8IZ81,Q15233,Q9NZ08,P04062,Q99735,Q08722,O75844,Q8N2K0,Q9NUD5,Q8IXJ6,P23246,Q9BY67,Q96PK6,P27361 28 +Regulation of oxidoreductase activity 0.5353945789928605 1.7822619105818112 0.0747065309857133 1.0 0.1742185826692235 18 P31749,P06280,P16435,P00374,Q8TCT9,Q8WTV0,P0DP25 7 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.5981823450451828 1.7806356502651342 0.0749719918382902 1.0 0.1746527649133805 13 Q9NR28,Q9BXK5,Q9NZJ7,Q96A26,O95831 5 +Negative regulation of establishment of protein localization to mitochondrion 0.5894649253196319 1.780399864176048 0.075010543989529 1.0 0.1746810025464401 3 P49257 1 +Regulation of morphogenesis of a branching structure 0.6817824336548726 1.7773146692582045 0.0755164814343678 1.0 0.1756735043293689 5 Q99623,Q9NQC3 2 +Protein maturation 0.3772992445125195 1.7770586764198752 0.0755585862402019 1.0 0.1757096046662543 68 P42892,Q9H9S5,Q8NCM8,Q86UY6,Q99538,Q5JRX3,Q9BXS4,Q9BU89,Q9UG56,P67812,Q8TCT9,Q9BU23,Q92896,P61009,O75844,O76024,O75503,O00170,O43464,Q15392,O75976,Q92542,Q96TA2,Q9Y4W6,Q10713,P78536,Q10471,Q9UNE7 28 +Endosome organization 0.4638264294581885 1.7765676656517244 0.0756393995926751 1.0 0.1758356637031271 31 Q9BRG1,O43633,Q14108,P61020,Q2M389,O43752,P51790 7 +Connective tissue development 0.4869753705164164 1.7733144826942715 0.0761766105463754 1.0 0.1768356933969074 26 Q9NX62,P16435,O15173,Q92896,Q96HY6,O75844,P43490 7 +Amyloid precursor protein biosynthetic process 0.7238441332103576 1.772342714707616 0.076337684756397 1.0 0.1771473871330856 6 Q9NQX7,Q9Y287 2 +Negative regulation of transcription by competitive promoter binding 0.5877331037746178 1.7707424973759898 0.0766035320352549 1.0 0.1776070458019312 3 P16220 1 +Purine nucleotide transport 0.641111079530416 1.7706652470176356 0.0766163848662893 1.0 0.1776070458019312 10 Q99808,P12236,Q8TB61,Q6NUK1,O43808,Q08722 6 +T cell differentiation in thymus 0.6187079633997166 1.770085632326894 0.0767128766281135 1.0 0.1777683736448816 11 P00813,P04062 2 +Positive regulation of membrane potential 0.7215225581123004 1.7615530073713157 0.0781448495856453 1.0 0.1803279716869868 6 Q8IWA4,P31751 2 +Endothelial cell proliferation 0.501697966216471 1.7607945224871588 0.0782731872832804 1.0 0.1804503209955275 21 P09601,Q8WTV0,Q9H2J4,P57105 4 +Vesicle cargo loading 0.5946812557660516 1.759808151546785 0.0784403404946212 1.0 0.1806314321703664 13 Q9NR31,Q15363,P49755 3 +Endoplasmic reticulum calcium ion homeostasis 0.6604935419437407 1.7590120400594065 0.0785754635650075 1.0 0.1808795676423319 9 P16615,P05067,Q07812,P51572,Q96A33 5 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.585440835392466 1.7579469610249558 0.0787565343361218 1.0 0.1811701828845907 3 O75844 1 +Negative regulation of g protein coupled receptor signaling pathway 0.7205748196493488 1.7571453129252237 0.0788930438382249 1.0 0.1814210600998011 6 P00813 1 +Atp transport 0.7197674669023509 1.7533891494209275 0.0795352322360138 1.0 0.182770636247502 6 Q6NUK1,Q08722,P12236,O43808 4 +Tetrapyrrole biosynthetic process 0.5930102850354664 1.749853844887019 0.080143536695626 1.0 0.1836576400906353 13 P22830,O00264 2 +Phospholipid biosynthetic process 0.3952032343064209 1.7475914572036102 0.0805347956635387 1.0 0.1842348440776487 59 O60762,Q9NX62,Q9Y2B2,O15269,P48651,O75874,Q92604,Q8TBX8,Q86UL3,Q9HBU6,O95674,Q9NPH0,Q9UG56,Q9BVG9,Q9HCL2,Q96JX3,Q86YN1,P35790,Q96N66,Q10713,O43292 21 +Positive regulation of monooxygenase activity 0.718422398634899 1.747128508681772 0.0806150492197081 1.0 0.1843546229387721 6 P31749,Q8WTV0,P00374,P16435 4 +Positive regulation of organic acid transport 0.699011567313387 1.7468468628339753 0.0806639051656701 1.0 0.1843990255173311 7 P14174 1 +Negative regulation of mrna splicing via spliceosome 0.5562874237194522 1.746393244060548 0.0807426430958631 1.0 0.1844549354374556 16 P22626,Q15287,P61978,Q16629,P38159,P98175 6 +Late endosome to golgi transport 0.5831853167554861 1.745342355546499 0.0809252932950137 1.0 0.1848083149228562 3 Q9UMY4,O60493 2 +Pigment granule localization 0.632860303010701 1.7429806240911914 0.0813369994040345 1.0 0.1856843623700393 4 Q15907,Q13561 2 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.6137542704954639 1.7420663094261035 0.0814968419889903 1.0 0.185920824544438 11 Q96K76,P10909,P14174 3 +Response to progesterone 0.6740940636010548 1.7396016131593242 0.0819289958054314 1.0 0.1867777624277669 5 P30536 1 +Bone morphogenesis 0.677072985819458 1.7375901365182156 0.0822830590517176 1.0 0.1874556143649781 8 O75844,Q9NX62,P16435 3 +Calcium ion import 0.5909054403940345 1.7373021545167129 0.0823338514693097 1.0 0.1874624856962866 13 P16615,Q9NWR8,Q8NE86,Q9BPX6,P21796,O75844,Q8IYU8 7 +Negative regulation of platelet derived growth factor receptor signaling pathway 0.5327019828351653 1.7367788519166791 0.0824262132900091 1.0 0.1874624856962866 2 O14964 1 +Organic hydroxy compound metabolic process 0.3421418443906723 1.736702903257077 0.0824396250480823 1.0 0.1874624856962866 113 P51648,Q9NX62,Q15125,P07858,O15269,Q16850,O75874,Q13510,O15118,P16435,P05067,P61916,Q9BQE5,P48735,Q14849,Q15800,Q14534,P04062,P38435,Q8WTV0,Q15392,P00374,O75845,Q10713 24 +Leukocyte migration 0.4066372670387106 1.7366086958789355 0.0824562635677266 1.0 0.1874624856962866 53 P00813,P31749,P04062,P09601,P35613,Q9H4A6,P05067,Q08722,O95747,Q8N5M9,P14174 11 +Intestinal absorption 0.6347569495964417 1.7362312606459305 0.0825229519310399 1.0 0.1875495836699598 10 Q16739 1 +Positive regulation of potassium ion transmembrane transporter activity 0.6733410100816304 1.7359009465195718 0.0825813504189914 1.0 0.1876091649638971 5 P05026,P54709 2 +Bone remodeling 0.6966938224292738 1.7356618318783348 0.0826236460266998 1.0 0.1876091649638971 7 O14773 1 +Trna transport 0.6732800764693321 1.735601453272048 0.0826343288258291 1.0 0.1876091649638971 5 P67809 1 +Regulation of mitophagy 0.696581382936776 1.735118938483215 0.0827197404950073 1.0 0.1877385868583459 7 P12235,P21796,P27544,Q9NQ88 4 +Cytosolic calcium ion transport 0.4855599437629421 1.7336823286424023 0.0829744636734803 1.0 0.1882520530099662 25 P16615,Q9NWR8,O95202,Q8NE86,P62258,Q9BPX6,P21796,Q07812,Q8IYU8,P0DP25 10 +Positive regulation of intracellular transport 0.3654731651793717 1.7332670830595245 0.083048208548019 1.0 0.188290089294634 75 Q92544,Q9P2W9,Q9NR31,O14737,Q9Y3B8,P46934,Q9Y282,P31751,P55786,P27105,P50402,O43464,P51572 13 +Cotranslational protein targeting to membrane 0.5785968215161043 1.7329918848508843 0.0830971111862381 1.0 0.1883363538511139 14 Q15629,Q15041,Q99442,P43307 4 +Metal ion export 0.6549545314123868 1.7301760455702218 0.0835988267912624 1.0 0.1893436073555357 9 P05023,O95202,P05026,P62258,P54709,P0DP25 6 +Synaptic vesicle priming 0.6303310434715483 1.7298365548531374 0.0836594813235558 1.0 0.1894160712803632 4 Q7L0J3 1 +Axis specification 0.6542636472439007 1.7265741543734532 0.0842441709780867 1.0 0.1904788662313293 9 Q15363,Q8N2A8,Q5T9L3,Q9UK61 4 +Glycoside metabolic process 0.6537526622645083 1.723909428399357 0.0847241949864534 1.0 0.1914332323642635 9 Q9NUJ1,P04062,P04066,Q9BTY2,P06280 5 +Regulation of systemic arterial blood pressure 0.6941102233764964 1.7231808912904332 0.0848558181864436 1.0 0.1916216501867602 7 P42785,P42892 2 +L glutamate transmembrane transport 0.6940364554696746 1.7228243314756315 0.0849202973204446 1.0 0.1916216501867602 7 Q15041,Q9H936,O75915,O75746,O60831 5 +Regulation of intrinsic apoptotic signaling pathway 0.4017196401562782 1.7203515548061012 0.0853685573919131 1.0 0.1924943008540273 54 Q9UMX0,P61978,O00571,O95881,P51572,P31749,Q9UL15,P45880,Q96K76,P18031,O75569,Q15233,P14174,O60313,Q8N2F6,P10909,Q07812,O43464,O75489,Q07820,P23246 21 +Gpi anchor metabolic process 0.7114317777915975 1.7145350416151246 0.0864305071665105 1.0 0.1944245139086005 6 O60762,O43292 2 +Negative regulation of vascular associated smooth muscle cell proliferation 0.7112869974434572 1.713859034750431 0.0865546181473719 1.0 0.1946374519686905 6 P09601 1 +Cellular response to increased oxygen levels 0.7109022065944453 1.7120621828363125 0.0868852096096204 1.0 0.1952479939850328 6 Q9Y487 1 +Photoreceptor cell differentiation 0.6266832150176711 1.7108531301136918 0.0871082287430735 1.0 0.1955496887781838 4 Q15555,P54802 2 +Photoreceptor cell development 0.6266832150176711 1.7108531301136918 0.0871082287430735 1.0 0.1955496887781838 4 Q15555,P54802 2 +Negative regulation of cell aging 0.6679861985964479 1.709551927772384 0.0873487615356896 1.0 0.1958900458056914 5 P14174 1 +Learning 0.4947316593683861 1.70860971401533 0.0875232680826592 1.0 0.1962148164037634 21 P50897,O00264 2 +Protein o linked mannosylation 0.6676756218330167 1.7080218644090797 0.0876322855805704 1.0 0.1962972138629379 5 Q9H9S5,O43505 2 +Protein mannosylation 0.6676756218330167 1.7080218644090797 0.0876322855805704 1.0 0.1962972138629379 5 Q9H9S5,O43505 2 +Vacuolar localization 0.5377022704797264 1.707931105701781 0.0876491266620562 1.0 0.1962972138629379 17 P33176,Q99584,P09601,Q9H0B6,Q9UNH7,Q86YV9,P51809,Q9BZG1 8 +Response to mitochondrial depolarisation 0.6905457298849493 1.7059392310829118 0.0880193944973692 1.0 0.1969262620965178 7 P04062,Q13501,Q16543,P52789,O43464 5 +Ubiquitin dependent erad pathway 0.4391055194670764 1.7047516928558866 0.0882407444430375 1.0 0.1972879161109726 37 Q9UBV2,Q9GZP9,Q9UMX0,Q8TCJ2,P27824,P46379,P33908,O43765,Q5VYK3,Q9BUN8,Q13438,Q9UBU6,O76024,P51572,Q96A33,Q9UNE7,P60604 17 +Mucopolysaccharide metabolic process 0.6495777555610206 1.702114668861506 0.0887338746166199 1.0 0.1981223572098788 9 P15586,O43505,Q9NX62,Q8NCH0 4 +Embryonic digit morphogenesis 0.6495029387404061 1.7017237202982067 0.0888071716537302 1.0 0.198180640265273 9 O95747,Q9NX62,P42892 3 +Aspartate transmembrane transport 0.6242845753962838 1.6983537557320096 0.0894410145938231 1.0 0.1993644740136853 4 O75746,Q9H936 2 +Regulation of nitric oxide synthase activity 0.6888803486428967 1.697874954778963 0.0895313651748404 1.0 0.1994313422448669 7 P31749,Q8WTV0,P00374,P06280 4 +Relaxation of cardiac muscle 0.5746589124010542 1.697568906726783 0.0895891554724703 1.0 0.19948937440068 3 P05023 1 +Neutrophil differentiation 0.6236838550806867 1.6952213229573398 0.0900334433746812 1.0 0.1997739221588318 4 Q8N5M9 1 +Positive regulation of protein localization to cell surface 0.6650507749228571 1.6950825648432015 0.090059759209006 1.0 0.1997739221588318 5 Q92544,P31749 2 +Positive regulation of protein export from nucleus 0.6269996142395442 1.6940507903780602 0.0902556321127412 1.0 0.200033357690512 10 Q9Y3B8,Q9C0E2,P50402,P62258 4 +Transepithelial transport 0.6642764436944959 1.691262768696 0.090786627488967 1.0 0.2010079802594918 5 P51798,P08183,O43865 3 +Mannosylation 0.6472911374387755 1.6901602610343422 0.0909972986806761 1.0 0.2013395202479374 9 O60762,Q9H9S5,O43505,Q9BT22,Q2TAA5 5 +Endoplasmic reticulum unfolded protein response 0.4799531499205272 1.689320391242854 0.0911580477199669 1.0 0.2016276898866336 25 Q9GZP9,P57088,O76024,Q92905,Q9BUN8,Q9Y4P3,Q96HY6,Q15363,Q13438,Q07812,P18031 11 +Detection of biotic stimulus 0.6637531218658264 1.688680516759676 0.0912806713136322 1.0 0.2017638651210019 5 P30536,P01889,Q8WTV0 3 +Antigen processing and presentation of peptide antigen via mhc class i 0.5936007670299847 1.687741328888649 0.0914608945330046 1.0 0.2020946345598889 12 Q6P179,P10321,P01889,Q9UIQ6,Q9NZ08 5 +Negative regulation of neuron apoptotic process 0.4688090060564892 1.6872294023112493 0.0915592498346431 1.0 0.2022443456407608 28 P07196,P50897,P04062,P09601,Q15058,Q99538,Q01105,Q07812,Q15233 9 +Negative regulation of smooth muscle cell proliferation 0.6865454511774232 1.6865594068049636 0.0916881029765648 1.0 0.2024613005586759 7 P09601 1 +Mitochondrial fission 0.5822990360581235 1.685834846721745 0.091827613913819 1.0 0.2027016367255944 13 Q9UDX5,Q9GZY8,Q9NUQ9 3 +Cell maturation 0.4793677515249419 1.6846783473283755 0.0920506462593406 1.0 0.2029228556130695 25 P09622,P04062,Q9NZJ7,Q86UL3,P05067,Q8N2A8,Q8IXJ6,O75503,Q9Y2W6 9 +Regulation of leukocyte degranulation 0.6627567012388129 1.6837622934737453 0.0922276170729219 1.0 0.2032451888079163 5 P09601,P11279 2 +Positive regulation of receptor mediated endocytosis 0.6249847525940498 1.6830699037840762 0.0923615598585574 1.0 0.2034457368622622 10 P10909,P50897 2 +Regulation of morphogenesis of an epithelium 0.6213365780455953 1.6829736781450404 0.092380187066674 1.0 0.2034457368622622 4 Q99623 1 +Phagosome maturation 0.6212669276773054 1.68261006547659 0.092450601877279 1.0 0.2034652107249208 4 Q9BZG1,P51149 2 +Phagolysosome assembly 0.6212669276773054 1.68261006547659 0.092450601877279 1.0 0.2034652107249208 4 Q9BZG1,P51149 2 +Organic hydroxy compound transport 0.4365682683812253 1.6811278025306635 0.0927380931418571 1.0 0.2040299792192189 37 O15118,P53985,Q96JX3,P61916,P30536,Q14849,Q8WTV0 7 +Sterol homeostasis 0.5910738378199433 1.6729830207296783 0.0943306386470843 1.0 0.2067765143676883 12 O15118,Q5BJF2,Q8WTV0 3 +Negative regulation of lymphocyte mediated immunity 0.5702176859501367 1.6726082368821726 0.0944044443130407 1.0 0.2068011178206451 3 P01889 1 +Positive regulation of mononuclear cell migration 0.5800127701454539 1.6721241218710534 0.0944998489183248 1.0 0.2069415180587173 13 Q08722,Q99538,O95747,P05067 4 +Amino acid import across plasma membrane 0.7023307121376242 1.671965037713242 0.0945312165168941 1.0 0.2069416396025681 6 Q15041,O75915,P30825,Q15758 4 +Neutral amino acid transport 0.7015641818333647 1.6683727041269545 0.0952417633600442 1.0 0.2080537776485523 6 Q9H9B4,Q96QD8,Q15758,Q96NB2 4 +Regulation of leukocyte mediated cytotoxicity 0.6632494058741406 1.6681241418334658 0.0952910856320423 1.0 0.2080537776485523 8 O15400,P04439,P01889,P11279,Q9NUQ9 5 +Positive regulation of cell killing 0.6632494058741406 1.6681241418334658 0.0952910856320423 1.0 0.2080537776485523 8 O15400,P04439,P01889,P11279,Q9NUQ9 5 +Regulation of regulated secretory pathway 0.5187031061693319 1.6667361642908118 0.0955668784967815 1.0 0.2084493399291186 18 P16615,P09601,P20339,P49841,P11279,Q4J6C6,P51809,P0DP25 8 +Negative regulation of response to external stimulus 0.4000064361881938 1.66400447597692 0.0961115349169732 1.0 0.2091541436504037 53 P00813,P04062,Q9UMX5,P80303,O43657,P14174 6 +Response to acidic ph 0.6176432993288059 1.663677780343588 0.0961768389605781 1.0 0.2092273629659187 4 Q15907 1 +Smad protein signal transduction 0.6620873651340967 1.662266111092834 0.0964594295293885 1.0 0.2097040689999109 8 P08670,Q8N1F7,Q9UIQ6 3 +Regulation of alternative mrna splicing via spliceosome 0.4377532076196863 1.6620110122070306 0.0965105664938421 1.0 0.2097462459578437 35 P62995,O43251,P31483,Q9UHX1,Q9UNW9,P52756,P38159,O75525,P98175 9 +Neurotransmitter transport 0.4556475319521541 1.6605775391552555 0.0967983230838165 1.0 0.2102482359515218 30 P16615,Q13277,P50897,O95721,Q99808,P20339,P49841,Q7L0J3,Q4J6C6,Q96QD8,P0DP25 11 +Amyloid precursor protein catabolic process 0.5044006542077027 1.6593147031604614 0.0970523940091556 1.0 0.2106412531200863 19 P49755,O75298,O95197,P10909,Q9NQC3,Q15392 6 +Golgi ribbon formation 0.6809026983810659 1.659168983948426 0.0970817456504438 1.0 0.2106412531200863 7 Q9Y3A6,O43752 2 +Homophilic cell adhesion via plasma membrane adhesion molecules 0.5663867658110189 1.6578490781339654 0.0973479324541199 1.0 0.2110802118075062 14 Q9BQT9,P35613,Q14574,Q9BY67,O15031,Q9H3S7,Q8TAB3 7 +Positive regulation of oxidoreductase activity 0.6199236948766045 1.6554427149597144 0.0978347274519111 1.0 0.2118577043675231 10 P31749,P16435,P00374,Q8WTV0,P0DP25 5 +Sodium ion transport 0.4498116203141038 1.6550454244998312 0.0979152840358654 1.0 0.2119626964274598 31 P31749,P05023,Q96PU5,Q9Y6M7,P05026,Q6P4Q7,P46934,Q9Y289,Q4KMQ2,O95747,O43865,P55011,P54709,P27105,Q96QD8 15 +Positive regulation of mitochondrial calcium ion concentration 0.6564624128958123 1.6526483323086976 0.0984024554344309 1.0 0.2128778487614252 5 Q8IYU8,P51572,Q9BPX6 3 +Neuromuscular process controlling balance 0.576440493125206 1.6506694313583137 0.0988060929725389 1.0 0.2135413565910758 13 P07196,O43251,P05067,O14773,P17900 5 +Positive regulation of autophagy 0.4541393422008858 1.6476458121707271 0.0994253736897738 1.0 0.2147393119985998 30 P12235,P27544,P09601,Q8TBX8,P49841,P21796,O15269,Q9BXS4,Q86UE4 9 +Regulation of natural killer cell activation 0.5653557056381832 1.6452246104091648 0.099923500111805 1.0 0.2155334243599607 3 Q8WXW3 1 +Cartilage development 0.5522432529025805 1.641973787641515 0.1005954364730954 1.0 0.2167130303861211 15 Q9NX62,P16435,Q92896,Q96HY6,O75844 5 +Camera type eye morphogenesis 0.677360674927588 1.6419443387235235 0.1006015399038613 1.0 0.2167130303861211 7 Q15555,Q8NBN7,Q07812,Q9P273,P54802 5 +Tail anchored membrane protein insertion into er membrane 0.6171464374217908 1.6402555157271967 0.100952050688889 1.0 0.2173264179162435 10 Q9P0I2,P46379,P49069,Q15006,Q5J8M3,Q9NPA0,O43681 7 +Glycosyl compound catabolic process 0.5958214127555786 1.6400570127980785 0.1009933132765155 1.0 0.2173444504866463 11 Q9NUJ1,P00813,P04062,P04066,Q9BTY2 5 +Sensory perception of light stimulus 0.513953809041906 1.6336500549589423 0.1023323511297391 1.0 0.219440139070878 18 O60313,O43924,Q15555,P50897,Q6P4Q7,Q9H6K4,O75569,Q9BV73 8 +Fat soluble vitamin metabolic process 0.6559879895248102 1.631472399510613 0.1027906790865085 1.0 0.2202086217448086 8 Q8N0U8,P04062 2 +Regulation of endocytic recycling 0.6113542327453412 1.6307508488973317 0.1029429024051025 1.0 0.2204331816726423 4 Q15907,Q9H4M9 2 +Positive regulation of anion transport 0.6557959138510003 1.6305014388296408 0.1029955613565016 1.0 0.2204331816726423 8 Q15041,P14174 2 +Programmed cell death 0.2797415535499583 1.6269529120175534 0.1037470989423285 1.0 0.2215394432665104 438 P00813,Q9NS69,P50897,P24390,P21796,Q15375,Q9UDX5,O00571,P61289,O95881,Q13510,P45880,P78318,P53634,P09601,Q99538,P11279,P14174,Q8N2F6,P04062,Q96TC7,Q96A26,Q6NUQ4,Q5J8M3,Q07812,O95831,O75844,Q01085,P98175,O95470,O43324,Q9Y3B8,Q9UHX1,Q9NQ88,P30536,Q8IXJ6,P23246,P78536,P52756,O14737,Q15058,P07858,Q13232,Q9NQX7,P06493,Q86XL3,P52789,Q9UL15,P12236,Q9Y2C4,Q15041,O95197,P05067,Q96K76,P18031,O75569,Q15233,Q9Y2I1,Q9HCL2,Q9NQC3,O76024,O43464,Q9UII2,P49736,P12235,Q9NR28,Q9NXR7,P49841,P05198,Q9BY67,Q05639,P27361,P07196,Q9NWS0,Q99623,Q96KA5,Q15287,O15269,Q92905,Q96HY6,Q9H3K2,Q9Y6C9,Q9UEE9,P31751,P10909,Q3ZCQ8,Q15392,Q92542,Q9NZJ7,O14681,Q9NVI7,Q9UMX0,P61978,Q01105,Q9H2J4,P51572,Q99720,P31749,P16435,Q9GZY8,Q9H4A6,Q86UE4,O60313,Q9BXK5,P46379,P31483,O75489,Q07820,Q13501,O75915,O95747,Q12981,Q8NDZ4 113 +Protein localization to golgi apparatus 0.6146419123503662 1.6265437346433385 0.1038340375616775 1.0 0.2216310005905396 10 P49755,Q9H4A6,P40616,Q8TD16 4 +Protein hydroxylation 0.5495870461536753 1.6250689102642797 0.1041478764920986 1.0 0.2221798953312718 15 P13674,O75718,Q92791,Q32P28 4 +Regulation of tumor necrosis factor mediated signaling pathway 0.6503721805869402 1.622469001180998 0.104702965265456 1.0 0.2229957326070508 5 Q8TCT8,P78536 2 +Intracellular sterol transport 0.6136723581047487 1.6212315867335323 0.1049679809263788 1.0 0.223100753072761 10 O15118,Q96JX3 2 +Cellular response to ethanol 0.5131695767978766 1.617876642605882 0.1056891849274674 1.0 0.2244536706894706 2 Q13131 1 +Vasodilation 0.5131695767978766 1.617876642605882 0.1056891849274674 1.0 0.2244536706894706 2 O60568 1 +Regulation of phospholipase activity 0.5919067203295167 1.617672973933023 0.1057330933213247 1.0 0.2244747875877402 11 Q99623,P50897,P18085,P00533,Q9Y263,P40616 6 +Regulation of osteoclast differentiation 0.6081539695886414 1.6139629926798194 0.1065354536512419 1.0 0.2259604663610584 4 P16220,P35222 2 +Steroid hormone biosynthetic process 0.6715199825611282 1.6134898318780198 0.1066381305844119 1.0 0.2261056801515491 7 Q53GQ0,P30536,Q14849 3 +Regulation of mitochondrial atp synthesis coupled electron transport 0.5596809250784531 1.6131884039758229 0.1067035819892172 1.0 0.226146796022981 3 Q9H3K2 1 +Retrograde transport vesicle recycling within golgi 0.5596348348087254 1.612927885472079 0.1067601760616887 1.0 0.226146796022981 3 Q8TBA6 1 +Intrinsic apoptotic signaling pathway 0.3609790889865454 1.6098852898327014 0.107422900931692 1.0 0.2274777161991518 82 Q9UMX0,P61978,O00571,O95881,P51572,P31749,Q9UL15,P45880,P09601,Q96K76,P18031,O75569,Q15233,P14174,O60313,Q8N2F6,P10909,Q07812,O95831,O43464,Q9NR28,P46379,O75489,Q9Y3B8,Q07820,O75915,P23246 27 +Collagen catabolic process 0.6063267822905869 1.6043683381544709 0.1086328857735567 1.0 0.2296720224176061 4 P07858 1 +Maintenance of location in cell 0.4066700062750096 1.6040115093955172 0.1087115156708531 1.0 0.2297647608150522 49 P31749,P24390,O95202,Q9H4A6,P10253,O43731,P30536,O43292,Q8NEW0,O15258 10 +Reactive oxygen species biosynthetic process 0.5890790482160747 1.6014797151165745 0.1092707093285267 1.0 0.2307990150055076 11 Q9BSK2,Q15067,P00403 3 +Amyloid beta formation 0.578267591115334 1.597911585894478 0.1100626552410901 1.0 0.2321749404686769 12 P49755,O75298,O95197,P10909,Q9NQC3 5 +Body fluid secretion 0.5332931821352812 1.5961697306492513 0.1104509036905518 1.0 0.2326968512881279 16 P00813,Q99808,Q13505,P16220,Q86UL3,P00403 6 +Receptor mediated endocytosis 0.3873100399039975 1.5952080283459866 0.1106657240526105 1.0 0.2330751339272476 56 P50897,Q14108,P61978,P20339,Q5VW38,P05067,P10909,Q96D71,P09496 9 +Deoxyribonucleoside triphosphate metabolic process 0.6487572031647365 1.594869266047171 0.1107414736545699 1.0 0.2330861144532016 8 P00813 1 +Peroxisome organization 0.5444975716772181 1.5926131427772838 0.1112470033152599 1.0 0.2337778839143252 15 Q9Y5Y5,Q9GZY8,O14734,P40855,O75381 5 +Caveolin mediated endocytosis 0.6039999111581054 1.5921398299349876 0.111353289338713 1.0 0.2339268560837744 4 P27361,Q96PU5 2 +Cellular response to lipoprotein particle stimulus 0.6851536480766687 1.5912174250211113 0.1115606526893007 1.0 0.2342135812019022 6 P31749,P78536,O15118 3 +Regulation of cardiocyte differentiation 0.5087303936075838 1.590697596545463 0.1116776480950205 1.0 0.234384749526831 2 P00533 1 +Segmentation 0.5438113547198082 1.588230693155572 0.112234182980091 1.0 0.23540327366405 15 Q15363,Q8N2A8,Q9Y2W6,Q9UK61 4 +Gland development 0.3560125204792194 1.5878258168809003 0.1123257318854393 1.0 0.2355205463295903 77 P00813,Q99623,Q05086,P35610,P52789,P00403,P31749,Q5T9L3,P09601,Q13505,Q86UL3,Q9Y297,P07602,P50416,P31751,Q07812,Q9NQC3,O75844,Q99808,Q9NZJ7,Q14103,P16220,P30536,Q9BY67,P27361 25 +Export across plasma membrane 0.6074414135021264 1.587039768404204 0.1125036379558377 1.0 0.2358187577704191 10 P05023,P05026,P62258,Q4KMQ2,P54709,P08183,P0DP25 7 +Negative regulation of membrane potential 0.5542175045754396 1.5822719963777478 0.1135874907133143 1.0 0.2375632044697133 3 O75915 1 +Regulation of protein monoubiquitination 0.507250665877486 1.5816258698830814 0.1137350046646696 1.0 0.2377212668655287 2 O75340 1 +Positive regulation of protein monoubiquitination 0.507250665877486 1.5816258698830814 0.1137350046646696 1.0 0.2377212668655287 2 O75340 1 +Skin development 0.4212766135883404 1.5795444952747364 0.1142112189736774 1.0 0.2385657225654343 42 P16949,P04062,Q9Y3B8,Q16739,O75844,Q13510,Q8NEY8 7 +Regulation of cell killing 0.6261655917531839 1.5791598177387784 0.1142994040242344 1.0 0.2386744901093729 9 O15400,P04439,P01889,P11279,Q9NUQ9 5 +Regulation of tube size 0.605767200157028 1.57783736640969 0.1146029770562782 1.0 0.239157270402571 10 Q9HB40 1 +Export from cell 0.3229697144101407 1.576781678057989 0.1148457688721167 1.0 0.2395126811220636 154 Q15907,Q13277,P50897,Q9UBV2,P05023,Q99584,O15498,P05026,Q92905,Q16850,O43768,Q9H4A5,P16615,Q5T9L3,O95721,Q96KC8,Q8N183,O43633,P09601,P20339,P51151,Q9H4A6,P11279,Q4J6C6,P51809,Q8N5M9,Q96PC5,P14174,O15126,P0DP25,P50416,P53985,O43760,Q32P28,P62258,Q86YV9,Q7L0J3,Q15758,Q9BRT2,P49755,Q8NE86,P49841,P16220,Q5JRA6,P08183 45 +Neuron development 0.3206362490802968 1.5744113826610004 0.1153923739960296 1.0 0.2405767191608075 206 P07196,Q13277,P50897,Q05086,Q14108,Q96PU5,P42892,P46934,Q16739,Q9NQX7,O15031,P31749,Q9UL15,P16949,O43251,Q9NR77,O00264,P35613,P05067,P54802,Q32P28,P04062,Q8N3R9,P08670,Q96G23,Q9NQC3,O75503,O43464,P10586,O14949,Q9UQB8,Q15555,Q9NZJ7,Q9Y6M7,P00374,P30536,Q9NZQ3,Q9UNW9 38 +Positive regulation of lymphocyte migration 0.6401732097859518 1.571772763893188 0.1160032601441471 1.0 0.2413776565658067 5 O95747,P05067 2 +Positive regulation of t cell migration 0.6401732097859518 1.571772763893188 0.1160032601441471 1.0 0.2413776565658067 5 O95747,P05067 2 +Mitochondrial acetyl coa biosynthetic process from pyruvate 0.5999669066083193 1.5709189891588855 0.1162014671843505 1.0 0.241501728497287 4 P09622 1 +Positive regulation of release of cytochrome c from mitochondria 0.6620544394243969 1.5672439941957623 0.1170576707407331 1.0 0.2429755483434376 7 Q96A26,Q9GZY8,O14737 3 +Detection of visible light 0.5507940309074593 1.5628638412037077 0.1180846241631066 1.0 0.2445779512119653 3 Q15555 1 +Cell recognition 0.4608419947799287 1.562846501189288 0.1180887036340416 1.0 0.2445779512119653 26 P35613,P45880,Q8WTV0,P05067 4 +External encapsulating structure organization 0.4536716341862403 1.5612493712540878 0.1184649241423796 1.0 0.2449733052744014 28 P13674,Q92791,Q96JX3,P05067 4 +Monocarboxylic acid transport 0.642053447804364 1.5608431368660962 0.1185607666459982 1.0 0.2450948097477017 8 Q9Y289,P28288,P53985,P14174 4 +Lymphocyte apoptotic process 0.4906423938587996 1.5599061288147746 0.1187820659445315 1.0 0.2454755077634174 19 P00813,P24390,P14174 3 +Glycerolipid biosynthetic process 0.4077812298776858 1.5596752795470918 0.1188366368081412 1.0 0.2455115138058786 47 O60762,Q9UG56,P35790,Q9NX62,Q9BVG9,Q96N66,Q9Y2B2,P48651,Q86UL3,Q9HBU6,Q9HCL2,O95674,Q9NPH0,Q10713,O43292,Q8WTV0,Q92604 17 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.6782065080505034 1.5584183009371335 0.1191341211187548 1.0 0.2458955048325581 6 P52789,O43464,Q16543,P04062 4 +Regulation of synaptic vesicle exocytosis 0.5813289906853174 1.5569939279545528 0.1194719270565609 1.0 0.2465157558279148 11 P16615,P20339,P49841,Q4J6C6,P0DP25 5 +Positive regulation of t cell mediated immunity 0.6774247812623854 1.5547227281557288 0.1200121192018079 1.0 0.2474758489250386 6 P01889,O15400,Q9NUQ9 3 +Regulation of intracellular protein transport 0.3525806455049606 1.551417323330651 0.1208017063970268 1.0 0.2487935424050951 76 Q92544,Q9GZP9,O14737,P06493,P55786,P27105,P51572,Q9BZL1,Q9GZY8,Q9Y282,Q13438,P49257,P18031,P50402,P60604,P62258,P31751,Q9NR31,O43464,Q9UII2,Q13263,Q9Y3B8,Q9C0E2,P49841 24 +Mitochondrial fragmentation involved in apoptotic process 0.6359859923659386 1.5509048472310565 0.120924488637228 1.0 0.2488912941150545 5 Q9GZY8 1 +Regulation of guanyl nucleotide exchange factor activity 0.5958827806491761 1.5493963789768297 0.1212864637037711 1.0 0.2495586048001941 4 P16949,Q9Y2S7 2 +Regulation of t cell mediated immunity 0.6582390731229079 1.548558824770894 0.121487810518543 1.0 0.2498950948387958 7 P01889,O15400,Q9NUQ9 3 +Negative regulation of immune effector process 0.6393963912513468 1.5473333776642952 0.1217828771528806 1.0 0.2502683566863768 8 P09601,Q08722,P01889 3 +Positive regulation of dna ligation 0.5016277005031128 1.5471002207703095 0.1218390807258207 1.0 0.2503060256502795 2 P09429 1 +B cell proliferation 0.5791408599097698 1.544407231765934 0.1224897092043586 1.0 0.2512521688800764 11 P00813 1 +Negative regulation of viral entry into host cell 0.5470692717584429 1.5417177334523149 0.1231422007000317 1.0 0.2517644591898554 3 O60493,Q12899 2 +Negative regulation of viral life cycle 0.5470692717584429 1.5417177334523149 0.1231422007000317 1.0 0.2517644591898554 3 O60493,Q12899 2 +Antigen processing and presentation of endogenous peptide antigen 0.638248719568575 1.5414940511425073 0.1231965896535016 1.0 0.2517644591898554 8 Q6P179,Q9NZ08,P10321,P01889 4 +Antigen processing and presentation of endogenous antigen 0.638248719568575 1.5414940511425073 0.1231965896535016 1.0 0.2517644591898554 8 Q6P179,Q9NZ08,P10321,P01889 4 +Negative regulation of guanyl nucleotide exchange factor activity 0.5467210884219604 1.5397394773099051 0.1236238698912333 1.0 0.2525034001025441 3 P16949 1 +Regulation of vascular endothelial growth factor receptor signaling pathway 0.6337079399950707 1.5395388721133707 0.1236727956017453 1.0 0.2525034001025441 5 O75340,P46934,P18031 3 +Negative regulation of vascular endothelial growth factor receptor signaling pathway 0.6337079399950707 1.5395388721133707 0.1236727956017453 1.0 0.2525034001025441 5 O75340,P46934,P18031 3 +Regulation of lipase activity 0.5468641203018917 1.5367284160027366 0.1243598294835428 1.0 0.2533020680397964 14 Q99623,P50897,P16435,P18085,P00533,Q9Y263,P40616 7 +I kappab kinase nf kappab signaling 0.3837194871854728 1.5363234331400737 0.1244590750700378 1.0 0.2534041981324338 55 P31749,Q5T9L3,Q8TB61,P09601,Q9P035,Q13501,Q8WVQ1,P98194,Q9Y297,Q96HY6,O43657,Q86UE4,Q9Y3E0 13 +Positive regulation of establishment of protein localization to mitochondrion 0.5773942272925368 1.5343519390655451 0.1249430944318823 1.0 0.2542302692612749 11 P55786,O14737 2 +Negative regulation of lipoprotein particle clearance 0.5929434744018327 1.533886934689133 0.1250574707734899 1.0 0.2543091767206138 4 Q92945,P30533 2 +Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.6366546131021195 1.533379313604322 0.1251824226475126 1.0 0.2544849680951742 8 Q96K76,P14174 2 +Negative regulation of low density lipoprotein particle clearance 0.5454720822052959 1.53264090394896 0.1253643572763576 1.0 0.2547764567156973 3 Q92945 1 +Negative regulation of cellular catabolic process 0.3355315691054574 1.5315944820887155 0.1256225350176827 1.0 0.2550658475981152 94 P10619,P49069,Q96HY6,Q9H2J4,P35637,O15118,Q9UL15,P31749,P09601,Q13151,Q99729,O60506,P07910,Q08J23,Q92804,P98175,Q14011,P46379,Q07820,P67809,Q14103,Q9NQ88,Q8IXJ6,P30536 24 +Vocalization behavior 0.4989641905889392 1.5307175384953318 0.1258392172686377 1.0 0.2551331453612485 2 Q7Z406 1 +Positive regulation of neuron projection arborization 0.4989641905889392 1.5307175384953318 0.1258392172686377 1.0 0.2551331453612485 2 O14641 1 +Receptor diffusion trapping 0.4989641905889386 1.5307175384953282 0.1258392172686386 1.0 0.2551331453612485 2 Q9NQX3 1 +Neurotransmitter gated ion channel clustering 0.4989641905889386 1.5307175384953282 0.1258392172686386 1.0 0.2551331453612485 2 Q9NQX3 1 +Regulation of atp metabolic process 0.4568891567883505 1.5306791901292804 0.1258486993308625 1.0 0.2551331453612485 26 P14406,Q9BSK2,P30536,P00403 4 +Fibroblast proliferation 0.4991687479135089 1.5300741750958289 0.1259983697362208 1.0 0.2553582415169222 18 P50402,P14174,O75844 3 +Natural killer cell degranulation 0.5444813176495267 1.5270076369873236 0.1267591123446947 1.0 0.2565852905010987 3 P11279 1 +Natural killer cell activation involved in immune response 0.5444813176495267 1.5270076369873236 0.1267591123446947 1.0 0.2565852905010987 3 P11279 1 +Positive regulation of leukocyte degranulation 0.5444813176495267 1.5270076369873236 0.1267591123446947 1.0 0.2565852905010987 3 P11279 1 +Excretion 0.6306864234945667 1.5244499193581065 0.1273963581404453 1.0 0.2574808963150469 5 P09601,Q9Y5X3 2 +Regulation of mitochondrial fusion 0.6298427034471772 1.5202338005338676 0.1284522251599649 1.0 0.2588766859651754 5 Q8N2A8 1 +Positive regulation of nitric oxide metabolic process 0.6701167599918507 1.5201285516945957 0.1284786699902822 1.0 0.2588766859651754 6 P10909 1 +Synaptic vesicle exocytosis 0.4976799524766069 1.5195982861647708 0.1286119689119129 1.0 0.2589873560447387 18 P16615,Q13277,O95721,P20339,P49841,Q7L0J3,Q4J6C6,P0DP25 8 +T cell apoptotic process 0.5536560423987067 1.512961811890111 0.1302893593540874 1.0 0.2619660407578838 13 P00813,P24390,Q9HCL2 3 +Regulation of anion transmembrane transport 0.6680536792427255 1.510347856574966 0.1309546863506105 1.0 0.2632236989328422 6 Q15041,P08183 2 +Acidic amino acid transport 0.5722842980808166 1.5048934011449708 0.1323514851265963 1.0 0.2653856083742946 11 Q15041,Q9H936,O75915,O75746,Q9UJS0,P55011,O60831 7 +Regulation of endocytosis 0.3855903962392965 1.5046540006007982 0.1324130551285802 1.0 0.2654035036730168 53 P50897,P61020,P51148,Q96PU5,P61978,P20339,Q8N6T3,P30533,P05067,Q4KMQ2,P10909,P57105,Q9H223,P18031,Q8NBU5,P0DP25 16 +Regulation of er to golgi vesicle mediated transport 0.6667748232175237 1.5042818840313672 0.1325088016142106 1.0 0.2654594331216484 6 Q9P2W9 1 +Positive regulation of protein localization to membrane 0.4176923533425365 1.5038487920067192 0.1326203047395193 1.0 0.2655218400555842 37 P31749,Q13277,O00264,O14737,Q13501,Q9GZY8,P98194,P31751,P27105,O15258 10 +Immune effector process 0.3481422188834403 1.5017016479054477 0.1331741781287543 1.0 0.2663886632121481 75 P00813,O15400,Q99584,P04439,P09601,P53634,P01889,P05067,P10909,P11279,Q08722,Q96FZ2,Q9NUQ9,Q8N5M9,P14174 15 +Negative regulation of muscle tissue development 0.5397815328234186 1.5002577097936618 0.1335476595338212 1.0 0.2668127212391246 3 Q8IXJ6 1 +Negative regulation of muscle organ development 0.5397815328234186 1.5002577097936618 0.1335476595338212 1.0 0.2668127212391246 3 Q8IXJ6 1 +Regulation of endoplasmic reticulum tubular network organization 0.5865363042310594 1.500023746379504 0.1336082514993077 1.0 0.2668531079356074 4 Q15041 1 +Cerebellar cortex development 0.5186493116139035 1.4995402748441364 0.1337335285964436 1.0 0.2670226255268567 16 P54802,P04062 2 +Positive regulation of nucleotide metabolic process 0.6653245301109976 1.4973998624736464 0.1342892440547967 1.0 0.2678894095859195 6 P00403 1 +Positive regulation of atp metabolic process 0.6653245301109976 1.4973998624736464 0.1342892440547967 1.0 0.2678894095859195 6 P00403 1 +Retina homeostasis 0.5391669482077563 1.4967563146712222 0.1344566771058986 1.0 0.2680112125260128 3 P51790 1 +Metanephric renal vesicle morphogenesis 0.4933412252145682 1.4960747792083806 0.1346341694032928 1.0 0.2680112125260128 2 P35222 1 +Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 0.4933412252145682 1.4960747792083806 0.1346341694032928 1.0 0.2680112125260128 2 P35222 1 +Positive regulation of mesenchymal cell proliferation 0.4933412252145682 1.4960747792083806 0.1346341694032928 1.0 0.2680112125260128 2 P35222 1 +Mesenchymal to epithelial transition involved in metanephros morphogenesis 0.4933412252145682 1.4960747792083806 0.1346341694032928 1.0 0.2680112125260128 2 P35222 1 +Metanephric nephron morphogenesis 0.4933412252145682 1.4960747792083806 0.1346341694032928 1.0 0.2680112125260128 2 P35222 1 +Cell death in response to oxidative stress 0.4556480933773892 1.495025242140422 0.1349078545223896 1.0 0.2684659802951779 25 P31749,Q9UL15,Q9NR28,Q9UMX0,P04062,Q07820,O75915,P23246,O43464,Q99720 10 +Deoxyribose phosphate catabolic process 0.6647951962898673 1.4948872804633948 0.1349438623907672 1.0 0.2684659802951779 6 P00813 1 +Regulation of gtp binding 0.6646857678382492 1.494367807851941 0.1350795108935281 1.0 0.2684850397186389 6 P16949,Q9Y2S7,O75503 3 +Definitive hemopoiesis 0.5386990649105204 1.494090195175962 0.1351520463420263 1.0 0.2684850397186389 3 O43251 1 +Cytokine production involved in immune response 0.5898357636018221 1.4899620797170507 0.1362342068552497 1.0 0.2700575504218194 10 P09601 1 +Regulation of t cell differentiation 0.559437098738347 1.4867359315839144 0.1370845687089903 1.0 0.2714989255611978 12 P00813 1 +Hormone catabolic process 0.5372808846007257 1.486006385953586 0.1372774318801033 1.0 0.2717219328328238 3 P42892 1 +Post translational protein modification 0.6085705075310888 1.485998957139917 0.1372793968420032 1.0 0.2717219328328238 9 Q92905,O75718,O60725,Q32P28 4 +Response to arsenic containing substance 0.5487317457874201 1.483015577065082 0.1380702721925912 1.0 0.2728787167825465 13 P07196,P36551,P09601,O00571,Q96QD8 5 +Digestive system process 0.548472690552624 1.4814384950460364 0.1384897631094408 1.0 0.2732991473246624 13 Q16739 1 +Interleukin 10 production 0.5826187674567804 1.4792829528318452 0.1390647070376787 1.0 0.2743518354662742 4 Q08722 1 +Positive regulation of cell activation 0.4013777788016002 1.4685844692630246 0.1419455298600129 1.0 0.278704101855266 46 P00813,P31749,P53634,P04439,P30825,Q9HCL2,P11279,Q08722,Q96FZ2,Q9NUQ9,P14174 11 +Regulation of t cell apoptotic process 0.6585915442174255 1.4654111562899474 0.1428087754800484 1.0 0.2802164516267761 6 P00813 1 +Regulation of protein localization to cilium 0.6185428050619074 1.4636580881328467 0.1432873924960565 1.0 0.2809281295298876 5 Q10713,Q96C92 2 +Negative regulation of double strand break repair via nonhomologous end joining 0.4880142053862153 1.4631877080440658 0.1434160233154169 1.0 0.2809281295298876 2 Q9UBB9 1 +Cellular response to molecule of bacterial origin 0.4327612357351262 1.4628074846769112 0.1435200644721916 1.0 0.2810169761591096 30 P31749,Q8WTV0,P08670,P30536,Q8IXJ6,Q86U42,Q9Y263,Q9NUQ9,Q86UE4,P14174 10 +Epidermis development 0.3786971229607898 1.4627028977403185 0.1435486929207374 1.0 0.2810169761591096 54 P51648,Q9Y3B8,Q9Y6M7,Q16739,O75844,Q13510,Q8NEY8 7 +Cell cell adhesion via plasma membrane adhesion molecules 0.4622030258734659 1.461822324817738 0.1437899047376858 1.0 0.2812501765382621 21 O00192,Q9BQT9,P35613,P98194,Q14574,O15031,P10586,Q8TAB3 8 +Iron ion transport 0.6225701685299535 1.461491545085088 0.1438805941709584 1.0 0.2812501765382621 8 Q15907,O15173 2 +Positive regulation of synaptic transmission 0.4643389426247858 1.4608582658286342 0.1440543418458519 1.0 0.2814233358732591 20 Q9BPZ3,Q13277,Q92542,Q9BQT9,Q13501,Q99538,P49841,P05067,Q14168 9 +Erad pathway 0.408894751821965 1.4581597520972631 0.144796514680777 1.0 0.2826437301203938 42 Q9UBV2,Q9GZP9,Q9UMX0,Q8TCJ2,P27824,P46379,P33908,O43765,Q8TCT9,Q5VYK3,Q9BUN8,Q13438,Q9UBU6,O76024,P51572,Q96A33,Q9UNE7,P60604 18 +Positive regulation of autophagy of mitochondrion 0.6570301546483791 1.4579840542029392 0.1448449383061443 1.0 0.2826437301203938 6 P21796 1 +Chemokine production 0.5840040906349535 1.4576647392161657 0.1449329756160895 1.0 0.282721970438824 10 P09601,P14174 2 +Hyperosmotic salinity response 0.6168892506980582 1.455362831890499 0.1455688404538335 1.0 0.2834603613905085 5 O95202 1 +Cellular response to salt stress 0.6168892506980582 1.455362831890499 0.1455688404538335 1.0 0.2834603613905085 5 O95202 1 +Cellular hyperosmotic salinity response 0.6168892506980582 1.455362831890499 0.1455688404538335 1.0 0.2834603613905085 5 O95202 1 +Midbrain development 0.4612166511604969 1.454264975021739 0.145872857026063 1.0 0.2839686928086157 21 Q5T9L3,O75489,P62258,P24539,Q8IXJ6,O15027,O14949,P0DP25 8 +Positive regulation of coagulation 0.5313548752485198 1.4521855800311965 0.1464500110987026 1.0 0.2849243813221447 3 Q9Y251 1 +Response to steroid hormone 0.3459422038668762 1.4518387700087052 0.1465464409793793 1.0 0.2850280837059205 77 P07196,O15118,Q05086,O43251,P16435,P04062,O15173,P46934,P30536,Q96HY6,O95831,O75874,P16278,Q9UBS8,P0DP25 15 +Mammary gland development 0.452700228481923 1.4479374914938752 0.1476345331649158 1.0 0.2863858613698058 24 P31749,Q99808,Q13505,P16220,P31751,Q86UL3,Q9Y297,Q07812,Q9NQC3,P00403 10 +Regulation of establishment of protein localization to mitochondrion 0.5105508946111277 1.4458121660527046 0.1482298928207399 1.0 0.2872877893408417 16 O14737,Q9BZL1,P49257,P55786,O43464,Q9UII2 6 +Protein localization to lysosome 0.5091870798172025 1.4367451923959926 0.1507904087297422 1.0 0.2913106726965409 16 Q14108,P46934,P10909,Q9NQC3,P13473 5 +Epithelial cell proliferation 0.379377537182531 1.4353789317718837 0.1511791462739931 1.0 0.2916354284077116 53 P31749,P07942,Q92542,P09601,Q9Y3B8,P57105,Q9Y297,Q07812,Q9H2J4,O95747,Q9NQC3,P78536,Q8WTV0,Q9UII2 14 +Protein insertion into mitochondrial inner membrane 0.6350329288779645 1.434407114790455 0.1514561184880563 1.0 0.2919992669450303 7 Q9Y5J7,O60220,Q9Y5J9 3 +Developmental maturation 0.4002133548157723 1.4333600843474752 0.1517549592592932 1.0 0.2924900920806851 45 P07196,P04062,Q9NZJ7,Q15125,P05067,Q86UL3,Q8N2A8,O75503,Q9Y2W6,P51790 10 +Carbohydrate derivative metabolic process 0.3068568057377321 1.4316258341478905 0.1522509321043696 1.0 0.2930187566330167 269 P00813,P50897,P00846,Q9BT22,Q16739,P06576,O75964,Q8WVC6,P00403,Q9NPH0,Q9BXS4,Q9UMR5,Q14168,P54802,Q9BRR6,P04062,P33908,Q16880,Q13126,Q8NCH0,O14734,Q07812,Q9Y2G5,Q9H0U3,Q8NBZ7,Q86YN1,P09622,Q9HC07,Q9NQ88,P06865,Q9HCC0,Q06203,P56385,O60762,Q8TCJ2,O60725,Q8TB61,Q13232,Q9Y2B2,P15586,Q9BTY2,Q9NQX7,P52789,P17900,Q9NUJ1,P05067,Q9UKU0,Q9Y287,P24539,Q8NBX0,Q9HCL2,Q7LGA3,P04066,O60502,O43292,P06280,Q9H9S5,O15118,O43505,Q10472,Q9H773,Q8IWA4,P46977,P36542,Q92542,Q99805,P22413,Q9H0P0,Q9NX62,P16278,Q8WVQ1,Q9H4A6,Q86UL3,O60476,O60313,P08236,Q53GQ0,P04843,P56134 79 +Negative regulation of mrna processing 0.4532773330276476 1.4310265185327764 0.1524226150976952 1.0 0.2932637738517228 23 P22626,Q15287,P61978,P50750,Q16629,P38159,P98175 7 +Negative regulation of rna splicing 0.4726640352629031 1.4288499686388567 0.1530473600236694 1.0 0.2942961416460337 19 P22626,Q15287,P61978,Q16629,P38159,P98175 6 +Activation of phospholipase d activity 0.5268257370294317 1.4262938631429354 0.1537835352950836 1.0 0.2954521467340719 3 P40616 1 +Negative regulation of cysteine type endopeptidase activity 0.4574279983220917 1.4252007759954497 0.1540991721017262 1.0 0.2957804191184903 21 P31749,P16435,Q9Y3B8,Q15041,Q96K76,O00571,Q15392 7 +Response to ph 0.6329967811736424 1.4243534404180678 0.154344184933945 1.0 0.2958851182933746 7 Q15907,Q99538,P04062 3 +B cell activation involved in immune response 0.5073125595170074 1.4242743891379903 0.1543670582350667 1.0 0.2958851182933746 16 P00813 1 +Negative regulation of amyloid precursor protein catabolic process 0.5582211109014633 1.4235238102932202 0.1545843647895863 1.0 0.2959615507793289 11 P10909,Q9NQC3,O95197,O75298 4 +Cognition 0.408927960373712 1.4232938592768147 0.154650986373527 1.0 0.2959615507793289 40 Q9BPZ3,P50897,Q05086,Q92542,O00264,Q99538,P05067,O75915,Q9H0U3,P17900 10 +Response to corticosteroid 0.4436882463495115 1.4226713764664538 0.1548314420003183 1.0 0.2959615507793289 26 P07196,P16435,P04062,O95831,P16278 5 +Vesicle targeting rough er to cis golgi 0.5579397563643241 1.4218917473606958 0.1550576793241478 1.0 0.2961757024145636 11 P49755,O75340,Q15363,O15027,Q9NR31 5 +Response to activity 0.5386860457026874 1.421741727838701 0.1551012416487827 1.0 0.2961757024145636 13 Q9UDX5 1 +Response to pain 0.5710290680852468 1.4177763215739378 0.1562560793103 1.0 0.2979504986040892 4 P30536 1 +Behavioral response to pain 0.5710290680852468 1.4177763215739378 0.1562560793103 1.0 0.2979504986040892 4 P30536 1 +Negative regulation of defense response 0.4111509849555506 1.4156062743521798 0.1568908132608326 1.0 0.298902099982947 35 O43657,P00813 2 +Regulation of protein localization to centrosome 0.6089040790915798 1.4152499790486244 0.1569952153987222 1.0 0.2989286599164952 5 P49841,Q9BV73 2 +Cell activation involved in immune response 0.409499783625136 1.4125722664340168 0.1577815283117651 1.0 0.3000800347086204 36 P09601,P00813,Q96FZ2 3 +Protein localization to vacuole 0.4508277307167614 1.4117165691607994 0.1580334326512278 1.0 0.3002544901914771 23 O75116,Q9BRG1,Q14108,P46934,O14964,P10909,Q9NQC3,P51149,P13473,Q9H9H4 10 +Digestion 0.5268856869960239 1.4116664620519117 0.1580481928615986 1.0 0.3002544901914771 14 Q16739 1 +Anterior posterior pattern specification 0.4702795848249419 1.4113785805596342 0.1581330152605935 1.0 0.3003164074302478 19 Q15363,Q8N2A8,Q5T9L3,Q9UK61 4 +2 oxoglutarate metabolic process 0.5940319403237996 1.4085951144374602 0.1589549243136352 1.0 0.3014000627675005 9 Q9H9P8,P48735 2 +Regulation of cell activation 0.3388670800278159 1.4085196722252356 0.1589772459990175 1.0 0.3014000627675005 72 P00813,P31749,P53634,P04439,P09601,P30825,Q9HCL2,Q9BWH2,P11279,Q8WXW3,Q08722,Q96FZ2,Q9NUQ9,O96005,P14174 15 +Inflammasome complex assembly 0.5687729251849498 1.405779341200947 0.1597896583971914 1.0 0.3026798086405955 4 O00571 1 +Detection of stimulus 0.5041235591726803 1.4030364738498562 0.1606059627750617 1.0 0.3038777005383291 16 Q15555,P04439,P01889,Q9BV73,P30536,Q8WTV0,P0DP25 7 +Regulation of protein targeting 0.4412800495560107 1.4028763452843462 0.1606537157960563 1.0 0.3038810554367878 26 O14737,Q9BZL1,Q9GZY8,P31751,P49257,P55786,P27105,O43464,Q9UII2 9 +Amyloid beta metabolic process 0.525153507342113 1.4007763275765062 0.1612809696578443 1.0 0.3048058131165836 14 P49755,O75298,O95197,P10909,Q9NQC3 5 +Response to iron ion 0.644285140115394 1.3972435576028932 0.1623403424142182 1.0 0.3060738968913821 6 P09601 1 +Negative regulation of neuron death 0.3966453081230682 1.3969988792979622 0.1624139081305764 1.0 0.3060738968913821 45 P07196,P31749,P50897,P04062,Q15058,P09601,O43464,Q99538,Q9UMX5,Q01105,Q9NQ88,Q07812,O76024,Q15233 14 +Purine ribonucleoside metabolic process 0.6099822603507457 1.3969756348878215 0.1624208981730195 1.0 0.3060738968913821 8 P00813 1 +Pigment biosynthetic process 0.4488038654223554 1.395743906798922 0.1627916273501477 1.0 0.3065213291045944 23 P00813,O00264,P22830 3 +Regulation of lymphocyte differentiation 0.5022207494255757 1.3903513457801149 0.1644222131834307 1.0 0.3088875517138413 16 P00813 1 +Negative regulation of calcium ion transport 0.5715346823298785 1.388395626218267 0.1650166074935342 1.0 0.3096058221725649 10 Q9UMX0,P21796 2 +Negative regulation of calcium ion transmembrane transport 0.5715346823298785 1.388395626218267 0.1650166074935342 1.0 0.3096058221725649 10 Q9UMX0,P21796 2 +Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator 0.4752885469073771 1.3843872656780412 0.1662399060668746 1.0 0.3116821387789998 2 P61254 1 +Triglyceride biosynthetic process 0.6243290968189223 1.3814958429468038 0.1671265551203635 1.0 0.3128680040223567 7 Q9HCL2,Q8WTV0,Q86UL3 3 +Mesenchymal cell proliferation 0.5637682788654925 1.379142327291614 0.1678508756251588 1.0 0.3137235398774533 4 O95747 1 +Determination of adult lifespan 0.623726172029943 1.3785112281071914 0.1680455036276589 1.0 0.3139985110192812 7 P04062 1 +Neuron maturation 0.6398555698624843 1.3760882216522017 0.1687943216442975 1.0 0.3150414209960921 6 O75503,P05067 2 +Antiviral innate immune response 0.6006529935914818 1.3737140679396116 0.1695304677402076 1.0 0.3160583529746212 5 P35232,Q99623,Q9NVI7 3 +Primary mirna processing 0.5626715650713037 1.3733007432429545 0.1696588716488056 1.0 0.316103750744339 4 P22626 1 +Multicellular organism growth 0.4224211385932219 1.3724467814754004 0.1699243952990019 1.0 0.3163465714172123 30 O95470,Q9HCL2,P05067,Q15363,O75844 5 +Establishment of protein localization to endoplasmic reticulum 0.4430634739123713 1.370883946195334 0.1704111365840501 1.0 0.3168956673280775 24 Q15629,P46379,Q9Y5M8,P33908,Q99442,O43681 6 +Cell communication by electrical coupling involved in cardiac conduction 0.6382956171922871 1.3686329594343658 0.1711140359149792 1.0 0.3180238085945156 6 P05023,P0DP25 2 +Pulmonary artery morphogenesis 0.4726250369932013 1.36785697398972 0.1713568498105031 1.0 0.3182960709380593 2 P98164 1 +Regulation of mrna splicing via spliceosome 0.3406416924260029 1.3672867637981816 0.1715354388505765 1.0 0.3185080182265405 70 P98179,Q9BWF3,Q15287,P61978,P26368,Q16629,Q07666,P22626,P62995,O43251,P38159,Q13595,P98175,Q14011,P31483,Q96E39,Q9UHX1,Q9UNW9,P52756,O75525 20 +Calcium ion transport 0.3608800172997854 1.3654489660272162 0.1721119827404449 1.0 0.319429400149284 60 P16615,Q9UMX0,Q9NWR8,O95202,P05026,P62258,Q9BPX6,P21796,P98194,Q8NE86,Q9HC07,Q07812,P30536,O75844,O76024,Q8IYU8,P0DP25 17 +Modification of synaptic structure 0.585323768084905 1.3620728099334856 0.1731749082145666 1.0 0.3209514773948599 9 O00264 1 +Positive regulation of lipid catabolic process 0.5604716059574524 1.3615782918632149 0.1733310099482081 1.0 0.3210607188194248 4 P31751 1 +Multi multicellular organism process 0.4210784568592342 1.3606715657206612 0.1736175042387198 1.0 0.3213203970325347 30 P07858,P35613,Q15363,Q9BQE5,Q9UIQ6 5 +Glycerophospholipid biosynthetic process 0.4006531210012031 1.3591789067357416 0.1740899036151395 1.0 0.3218744569499508 41 O60762,Q9UG56,P35790,Q9NX62,Q8TBX8,Q9BVG9,Q96N66,Q9Y2B2,P48651,Q86UL3,Q9HBU6,Q9HCL2,O95674,Q9NPH0,Q10713,O43292 16 +Oligosaccharide metabolic process 0.6362885637613594 1.3590372396552195 0.1741347884988482 1.0 0.3218744569499508 6 P10253,P17900,P06280 3 +Regulation of leukocyte mediated immunity 0.4252034435648713 1.3576332765244743 0.1745800784760758 1.0 0.322470580952595 29 O15400,P04439,P09601,P01889,P11279,Q96FZ2,Q9NUQ9 7 +Response to l phenylalanine derivative 0.4708493637170842 1.3568305139793375 0.1748350695197689 1.0 0.3228513479899839 2 Q96SB3 1 +Regulation of dna damage response signal transduction by p53 class mediator 0.5658112237209311 1.3565143347497273 0.1749355775726493 1.0 0.3229467128987819 10 P14174 1 +Receptor recycling 0.5840084638284005 1.3550366927364792 0.175405866838052 1.0 0.323634107742235 9 P49069 1 +Triglyceride metabolic process 0.5272106812125781 1.3514758575734638 0.1765430484455024 1.0 0.3254436682078575 13 P50416,Q9UBV2,Q96N66,Q86UL3,Q9HCL2,Q8WTV0 6 +Homologous chromosome pairing at meiosis 0.5830606568056331 1.3499650539796637 0.1770271926572602 1.0 0.3256967157638722 9 Q9BTX1,P46379,Q92791 3 +Positive regulation of extrinsic apoptotic signaling pathway 0.5643128932494021 1.348160044022228 0.1776069126787631 1.0 0.326419378724679 10 Q9NQX7 1 +Peripheral nervous system development 0.5063296552846348 1.3467761030793752 0.1780523533531783 1.0 0.3267951005357213 15 P51648,P31749,Q9NR77,Q16880,Q8N3R9,P31751,Q8IXJ6 7 +Hindlimb morphogenesis 0.5129215393860166 1.3466033109293942 0.1781080272552078 1.0 0.3267951005357213 3 O95747 1 +Embryonic hindlimb morphogenesis 0.5129215393860166 1.3466033109293942 0.1781080272552078 1.0 0.3267951005357213 3 O95747 1 +Ubiquinone metabolic process 0.6332735817088717 1.3446150995041093 0.1787495646317216 1.0 0.3278811747574378 6 Q8NI60 1 +Negative regulation of ion transmembrane transporter activity 0.4950923091966914 1.3427483208512867 0.1793534824184723 1.0 0.3286241101479578 16 Q9UMX0,P62942,Q96PU5,P62258,P46934,O95747,P0DP25 7 +Keratinocyte differentiation 0.4395304825923961 1.342538494168269 0.179421457749473 1.0 0.328657542756726 24 Q9Y3B8,Q13510,Q16739 3 +Regulation of calcium mediated signaling 0.5816418602948618 1.3423710156339277 0.1794757277421794 1.0 0.3286658588661856 9 P00813 1 +Glycerophospholipid catabolic process 0.6163360914956059 1.3418953315444648 0.1796299356716955 1.0 0.3288571315385694 7 Q8WTV0 1 +Purine containing compound transmembrane transport 0.5986678847753266 1.338802439330986 0.1806349964765794 1.0 0.3303311266501697 8 Q99808,P12236,O43808,Q8TB61 4 +Skeletal muscle cell differentiation 0.5985908868057865 1.3384060237347972 0.1807641163409949 1.0 0.3304758077171883 8 P17844,Q9Y5Q8,Q9BYT8,Q92841,P50402,Q9BRT2 6 +Regulation of ion transport 0.3257140553981535 1.337551390172988 0.1810427193761681 1.0 0.3308057833926622 93 Q15907,Q99623,Q99996,Q9UMX0,P05023,Q96PU5,P62942,P05026,P21796,P46934,P27105,O00483,P33176,P31749,Q9BVC6,Q15041,Q9UNH7,P05067,P54652,P51809,P54709,Q9HD26,P14174,P0DP25,P35222,P62258,Q4KMQ2,Q07812,Q7L0J3,O43865,O75844,O76024,P0CG08,Q9BSH4,Q00535,P30536,P08183,O75915,P55011,O95747,Q13642 41 +Sodium ion homeostasis 0.6154589155526503 1.3375452733329167 0.1810447145606384 1.0 0.3308057833926622 7 P05023,Q96PU5,P05026,Q9Y5X3,P54709 5 +Fatty acid beta oxidation using acyl coa oxidase 0.631760124108887 1.337372221653255 0.1811011671395239 1.0 0.3308174719804073 6 O15254 1 +Nerve development 0.5982153324806585 1.3364724283138052 0.181394906585588 1.0 0.3312624862183341 8 P42892 1 +Response to mineralocorticoid 0.6139269343399453 1.3299460731069943 0.1835360397397556 1.0 0.3342092814871979 7 P07196,O95831 2 +Positive regulation of protein tyrosine kinase activity 0.5919377066710916 1.329757105048402 0.1835983131182281 1.0 0.3342092814871979 5 P78536,P18031 2 +Vascular transport 0.503412974277021 1.3278380335059108 0.1842316193294857 1.0 0.3351463727356375 15 P53985,Q99808,P30825,Q9Y289,Q96QD8,P08183 6 +Positive regulation of cell death 0.3151219365268948 1.327369662387258 0.1843864301155315 1.0 0.3352878536833434 124 Q9NS69,O14737,Q15375,O00571,Q9NQX7,P51572,P00403,P53634,Q9Y6C9,P09601,Q96A26,P10909,Q07812,O95831,O43464,P98175,Q9NR28,O43324,Q9NZJ7,Q07820,Q13501,Q9NQ88,Q8IXJ6,P30536,O75915,Q05639,P52756 27 +Natural killer cell mediated immunity 0.541673989035524 1.3272957894896742 0.1844108561263358 1.0 0.3352878536833434 11 P04439,P01889,P11279,Q9BY67,P51809 5 +Natural killer cell activation 0.5957779951812106 1.3239196811479454 0.1855297210842179 1.0 0.3372293527628153 8 Q96L92,Q8WXW3,P11279,P46379 4 +Peptidyl proline modification 0.4012737774481962 1.322940827025351 0.1858550567553334 1.0 0.3376349835338094 35 P13674,Q9NWM8,O75718,Q9BV86,O95302,Q9Y680 6 +Neutral lipid biosynthetic process 0.5955276654818312 1.322630074191204 0.1859584278967838 1.0 0.3377131171556988 8 Q86UL3,Q8WTV0,Q9HCL2 3 +Regulation of inflammatory response 0.3992083214934312 1.3207060338459748 0.1865994014135059 1.0 0.3385219445352349 38 P00813,P04062,Q99735,P05067,Q8N2K0 5 +Protein lipid complex subunit organization 0.5900527902287209 1.3202401730511102 0.1867548431399219 1.0 0.3387109655081625 5 Q8WTV0,P35610 2 +Protein targeting to lysosome 0.5220822435217549 1.3199908449321716 0.1868380746452933 1.0 0.3387689534515071 13 P10909,Q14108,P46934 3 +Regulation of mammary gland epithelial cell proliferation 0.5523749898711254 1.318388017982487 0.1873737897728302 1.0 0.3395864736409395 4 Q07812,Q9NQC3 2 +Calcium ion transmembrane transport 0.3907749712376129 1.3160914842251188 0.1881433388514279 1.0 0.3407097714773157 44 P16615,Q9UMX0,Q9NWR8,O95202,P05026,P62258,Q9BPX6,P21796,P98194,Q8NE86,Q9HC07,Q07812,Q8IYU8,P0DP25 14 +Vesicle targeting to from or within golgi 0.5113429391531922 1.3137194110429995 0.1889406462207317 1.0 0.3419246251020854 14 Q15363,Q9BVK6,Q9NR31 3 +Polyol biosynthetic process 0.5385532715030885 1.3090978075691788 0.1905012218320183 1.0 0.3445495726792349 11 Q13510,P00374,O15269,P04062 4 +Cellular response to estradiol stimulus 0.6096384368814047 1.308661546609449 0.1906490227536634 1.0 0.3446387831999348 7 O95831 1 +3 phosphoadenosine 5 phosphosulfate metabolic process 0.5501633881622803 1.3065788090554025 0.1913557974574484 1.0 0.345632813718578 4 Q8TB61 1 +Carbohydrate transport 0.4394093923706273 1.302975182921916 0.1925832342918501 1.0 0.3472803807462039 22 P31749,O75298,P31751,P22413,L0R6Q1,Q16625,P52789 7 +Positive regulation of phospholipase activity 0.5906840868452969 1.297665184865591 0.1944024120865521 1.0 0.3496381132681914 8 Q99623,P18085,P00533,Q9Y263,P40616 5 +Labyrinthine layer blood vessel development 0.6230889106509163 1.295836406462379 0.195031852324359 1.0 0.3503071878262588 6 Q15363 1 +Regulation of amino acid transport 0.607051421968733 1.2958137614029066 0.1950396557984171 1.0 0.3503071878262588 7 Q15041,Q7L0J3 2 +Reticulophagy 0.5480350079679852 1.295209764442636 0.1952478773071726 1.0 0.3504598645092623 4 Q96HY6 1 +Regulation of golgi organization 0.5900762225134165 1.2945305060789594 0.195482239063339 1.0 0.3507852614633743 8 Q9P2W9,Q99996,Q13190,Q5VU43,P27361 5 +Regulation of bone remodeling 0.4604912696064006 1.292423072595862 0.1962106707123978 1.0 0.3517495616541828 2 P41240 1 +Regulation of bone resorption 0.4604912696064006 1.292423072595862 0.1962106707123978 1.0 0.3517495616541828 2 P41240 1 +Vascular process in circulatory system 0.4000990902657898 1.2917043209089334 0.196459560530928 1.0 0.3520610725457981 33 O75116,P53985,Q96QD8,Q99808,P30825,P42892,Q9Y289,Q16625,Q9HB40,P08183 10 +Suppression of viral release by host 0.5472312703582953 1.2909154713088606 0.1967329900045462 1.0 0.3524554976796005 4 Q13263,Q12899,P19474 3 +Regulation of membrane potential 0.3454883282810193 1.290105918897024 0.1970138850948188 1.0 0.352547720583427 65 P05023,Q96PU5,P05026,Q9BSK2,P46934,P31749,P16615,P05067,Q14168,P0DP25,P04062,P62258,P31751,Q07812,O75844,Q8IWA4,Q9UII2,Q9UQB8,Q99808,P09622,P30536,O75915 22 +Positive regulation of carbohydrate metabolic process 0.5892119023875625 1.2900727319286225 0.1970254064316678 1.0 0.352547720583427 8 P31751,P05067 2 +Regulation of adaptive immune response 0.4376819930088761 1.2894353116368622 0.1972467918544285 1.0 0.352802177906879 22 P00813,O15400,P01889,Q96FZ2,Q9NUQ9 5 +Regulation of long chain fatty acid import into cell 0.5466632948531208 1.2878805107073448 0.1977875606944148 1.0 0.3533868582398993 4 P31751 1 +Ketone biosynthetic process 0.58862572948924 1.2870491319552173 0.1980771637764853 1.0 0.3536631848306923 8 Q8NI60,Q14849 2 +Sarcoplasmic reticulum calcium ion transport 0.5886114957483852 1.2869757075943005 0.1981027553704377 1.0 0.3536631848306923 8 O75844,P0DP25 2 +Modified amino acid transport 0.5882068718387158 1.284888391481385 0.1988312880703209 1.0 0.354867940279976 8 O43772,Q96QD8,Q9H2D1 3 +Regulation of dna ligation 0.5017761989342856 1.2825455206163772 0.1996513472480976 1.0 0.356139204848226 3 P09429,Q9UBB9 2 +Heparan sulfate proteoglycan metabolic process 0.5824991070456027 1.2820707837503666 0.1998178167696747 1.0 0.3562438497520313 5 Q99805,Q7LGA3 2 +Intrinsic apoptotic signaling pathway in response to oxidative stress 0.4641022958374684 1.28139340042996 0.2000555210541257 1.0 0.3564753137359711 18 P31749,Q9UL15,Q9NR28,Q9UMX0,Q07820,O75915,P23246,O43464 8 +Peptidyl arginine methylation to asymmetrical dimethyl arginine 0.5014801657785829 1.280842395210849 0.20024902954705 1.0 0.3567239450879929 3 Q86X55,Q99873 2 +Positive regulation of tumor necrosis factor mediated signaling pathway 0.5442691692080646 1.2750847765115767 0.2022792370936241 1.0 0.3597587400300759 4 P78536 1 +3 utr mediated mrna stabilization 0.6026247770673241 1.273817233248273 0.2027281962307134 1.0 0.3602663750709291 7 P98175,Q13151 2 +Lipid storage 0.4512590607025433 1.2713704843145677 0.2035968778600032 1.0 0.3612683969159336 19 Q9H6V9,Q8WTV0,P04062,P22413,P17900,Q14534 6 +Regulation of response to endoplasmic reticulum stress 0.4280932287066465 1.2713053774352243 0.2036200300365944 1.0 0.3612683969159336 25 O60313,P46379,Q9UMX0,P57088,Q92905,P10909,Q07812,Q96HY6,P18031,O95881,P51572 11 +Oocyte construction 0.4994656172071898 1.2692504759139804 0.2043517434708559 1.0 0.3622993455275483 3 Q8N2A8 1 +Negative regulation of lipid transport 0.4994588857231246 1.2692117369091789 0.2043655560790891 1.0 0.3622993455275483 3 P31751 1 +Regulation of cell death 0.2865670252049558 1.2683327756536285 0.2046791371627416 1.0 0.362757955888592 359 P07196,P00813,Q9NS69,P50897,Q9UMX0,O14737,P61978,P07858,P21796,Q01105,O15269,Q92905,Q15375,Q96HY6,O00571,Q9NQX7,P61289,Q86XL3,O95881,Q13510,P51572,Q9H3K2,Q99720,P00403,O15118,Q9UL15,P31749,P45880,O43633,Q9Y6C9,P16435,P09601,Q15041,P78318,P53634,Q9H4A6,Q96K76,Q86UE4,P14174,O60313,Q9BXK5,P04062,Q96A26,Q9UEE9,Q9UMX5,P31751,Q9HCL2,P10909,O95831,Q9NQC3,O43464,Q15392,P98175,Q9NR28,P46379,Q9NZJ7,Q9Y3B8,O75489,Q07820,Q13501,Q8NDZ4,P30536,O75915,O95747,Q9NVI7,Q05639,Q12981,P52756 68 +Regulation of amyloid beta clearance 0.6164653239966398 1.26407048484683 0.2062047292423021 1.0 0.3648747136713186 6 Q16850 1 +Positive regulation of chromatin organization 0.5480836047271134 1.257483327568126 0.20857867250426 1.0 0.368483412611776 10 Q9UK61,Q8NEY8 2 +Regulation of leukocyte chemotaxis 0.4493268836292086 1.2570920931759215 0.2087202899398903 1.0 0.3686350604523611 19 P27361,Q8NE86,Q99538,Q4KMQ2,O95747,P78536,P14174 7 +Regulation of leukocyte apoptotic process 0.4822211800764304 1.2565091090161649 0.2089314454329187 1.0 0.368825873087115 16 P00813,P14174 2 +Multicellular organism aging 0.5475367779727327 1.25442295714237 0.2096883125588591 1.0 0.3698505625037362 10 P04062 1 +Negative regulation of cell projection organization 0.4044736217869916 1.2534206132611914 0.2100526735707943 1.0 0.3703943755681377 31 Q9UL15,Q9NR77,P08670,Q96G23,Q9NQX7 5 +Response to metal ion 0.338051368691393 1.2467691899997897 0.2124821406132235 1.0 0.3740795064765036 67 Q96PU5,P46940,P46934,Q86YQ8,P06493,P31749,O15118,O75131,P36551,P09601,Q6NUK1,Q99538,P35613,P05067,O60888,Q14168,P0DP25,O75340,P50995,O75746,O43865,P48637,Q92542,Q14103,P16220,P05198,Q9NQ88,P30536,P55011,P27361 30 +Positive regulation of transport 0.3044903179432419 1.2453130354206725 0.2130167058949086 1.0 0.3749207481383358 194 Q92544,P50897,Q13642,Q99996,O14737,Q96PU5,P61978,P05026,P22307,P46934,P06493,P55786,P27105,P51572,Q07666,Q9H4A5,P33176,P31749,Q5T9L3,O43633,Q9BZL1,Q15041,Q9GZY8,P20339,P51151,Q9Y282,Q9H4A6,P11279,P51809,P54709,P50402,P14174,P0DP25,O95563,P62258,P98194,P31751,Q4KMQ2,P10909,Q07812,Q08722,O43865,Q9Y5X3,Q16625,O76024,Q9Y6B6,Q9NR31,O43464,Q9UII2,Q9P2W9,Q12907,P49755,Q13263,Q9Y3B8,Q9C0E2,Q8NE86,P49841,P16220,Q9NV96,P30536,Q9Y263,P55011,P51149,P08183,Q8NBU5 65 +Plasma membrane organization 0.399095351697173 1.2433884985917776 0.2137247064839831 1.0 0.3758665740161374 32 P31749,O43633,Q8N3R9,P31751,P10909,Q16739,Q9UQB8 7 +Positive regulation of homotypic cell cell adhesion 0.4525007398638734 1.2426598043303754 0.2139932219163129 1.0 0.3759386506233266 2 Q12955 1 +Positive regulation of endothelial cell development 0.4525007398638707 1.242659804330358 0.2139932219163194 1.0 0.3759386506233266 2 P35611 1 +Positive regulation of immune effector process 0.3900181405799416 1.239558333468901 0.2151388001004681 1.0 0.3772492252226039 37 O15400,P04439,P09601,P01889,P11279,Q96FZ2,Q9NUQ9,P14174 8 +Placenta development 0.4156527506893792 1.2393517991639529 0.2152152435114873 1.0 0.3772831682672201 28 Q15363,P00813,P07858 3 +Negative regulation of mhc class ii biosynthetic process 0.4519088487718346 1.2389717697285485 0.2153559528590267 1.0 0.3774297248595353 2 Q15545 1 +Protein k29 linked ubiquitination 0.4940793368857364 1.2382430489096712 0.2156259537330509 1.0 0.3777026048825162 3 Q96J02,Q15386 2 +Positive regulation of small molecule metabolic process 0.479449546404169 1.2378974536261578 0.2157540866406795 1.0 0.3777882746110698 16 P50416,P31749,P16435,P31751,P05067,P00403 6 +Negative regulation of autophagy 0.4152990966923907 1.2363266133751496 0.2163371824766908 1.0 0.3785471111963066 28 P10619,P31749,O15118,P09601,Q07820,Q9NQ88,P30536,Q8IXJ6 8 +Response to ischemia 0.5441035765994235 1.2352025250948222 0.2167551397491927 1.0 0.3789167606916712 10 Q13501,P52789,O95831,Q9NQ88 4 +Membrane biogenesis 0.4151494175147738 1.235046105582328 0.2168133455017615 1.0 0.3789167606916712 28 Q9Y5Y5,Q9H6H4,O43633,Q16739,Q86XL3,Q6NUK4 6 +Regulation of mesenchymal cell proliferation 0.4934872705743088 1.2348336113171765 0.2168924354208761 1.0 0.3789167606916712 3 P35222,P02545 2 +Mesenchymal to epithelial transition 0.4934872705743073 1.2348336113171672 0.2168924354208794 1.0 0.3789167606916712 3 P80723,P35222 2 +Metanephros morphogenesis 0.4934872705743073 1.2348336113171672 0.2168924354208794 1.0 0.3789167606916712 3 P80723,P35222 2 +Positive regulation of toll like receptor signaling pathway 0.5726063959449232 1.2320212755522597 0.2179411367415327 1.0 0.3802462969178431 5 Q9NQC3 1 +Positive regulation of sequestering of triglyceride 0.450429121041737 1.229750839621149 0.2187904224445334 1.0 0.3814259831010079 2 Q9BXB4 1 +B cell apoptotic process 0.5774403268665802 1.2293002423567376 0.2189592564609137 1.0 0.3815365512546876 8 P00813 1 +Organonitrogen compound catabolic process 0.2771433320843449 1.2288656953100514 0.2191221652382395 1.0 0.3817022641169018 387 P10619,P00813,Q9UBV2,P50897,Q9GZP9,P28074,P49069,Q9BRG1,Q9UMX0,P07858,O00231,Q13190,P42892,P30519,P46934,P15586,Q16850,Q96HY6,Q9H2J4,P55786,Q13510,P17900,P16278,P51572,Q9NUJ1,P31749,Q9UL15,P09601,Q9BQT8,Q9BQG2,Q6P179,Q96K76,Q9BUN8,Q9Y297,P54802,Q9UG56,Q8N511,P04062,Q9H773,P33908,Q8TCT9,P24941,P10909,Q9UJX3,Q9UHG3,Q9Y5X3,O75844,O75503,O14773,Q9UIQ6,Q8WTV0,O43464,P28072,Q96A33,Q8N2K0,O95470,P04066,O60502,P06865,Q05639,Q9UBS8,P06280 62 +Tolerance induction 0.5351498077051032 1.2263104644913332 0.2200818648939577 1.0 0.38307112064371 4 P01889 1 +Skeletal system morphogenesis 0.4313718858023901 1.2239384812066187 0.2209754356229809 1.0 0.3839186787676869 21 O95470,Q9NX62,P16435,Q92896,O75844 5 +Negative regulation of muscle cell apoptotic process 0.5344471733164987 1.2225506595216982 0.2214994586937098 1.0 0.3847279691213477 4 P09601 1 +Regulation of cardiac conduction 0.4910838599112374 1.2209917464962077 0.2220891447809871 1.0 0.3855495555181361 3 P16615 1 +Protein n linked glycosylation 0.4327215391708559 1.2199352961199708 0.2224894042193193 1.0 0.3858390114105172 20 Q96AA3,P46977,Q8TCJ2,Q86YN1,Q9HC07,Q9BT22,Q9H0U3,P04843,Q2TAA5 9 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.5409064029288629 1.217294750786139 0.2234920907839264 1.0 0.3870700282995203 10 O43657 1 +Response to testosterone 0.5141672692707475 1.2164265258984035 0.2238224843354372 1.0 0.3874391825492155 12 P04062 1 +Very long chain fatty acid metabolic process 0.5139933160745271 1.2153820367851524 0.2242204159693432 1.0 0.3879247982045523 12 Q9P035,Q9UKU0,Q15067 3 +Negative regulation of interferon beta production 0.4477656111275611 1.2131506299075865 0.2250722357112953 1.0 0.3889912149100289 2 Q86UT6 1 +Sodium ion transmembrane transport 0.4234303685517332 1.212799503973172 0.2252064851214692 1.0 0.3891214797824288 24 P05023,Q96PU5,Q9Y6M7,P05026,Q6P4Q7,P46934,Q4KMQ2,O95747,P55011,P54709,P27105 11 +Regulation of production of molecular mediator of immune response 0.4208472029543867 1.2119871782746048 0.2255172887271836 1.0 0.3894548631298555 25 P09601,P14174 2 +Response to estrogen 0.5129326729562954 1.209012894360145 0.2266578916005501 1.0 0.3911700807036826 12 P09601 1 +Copii coated vesicle budding 0.42911916722774 1.2064446699464015 0.2276460810376188 1.0 0.3923488758853509 21 P49755,O75340,Q5JRA6,Q15363,O15027,Q9NR31 6 +Negative regulation of cell population proliferation 0.3093364110284358 1.205271626760429 0.2280984591676995 1.0 0.392732459116915 109 Q9NR77,O14737,Q32P28,P09601,Q9Y3B8,P09493,Q9NPI1,P57105,P05067,P30536,Q96G23,Q71SY5,P50402,P52756,P98175 15 +Protein deglycosylation 0.5880234358730095 1.2011720881598769 0.2296844541709668 1.0 0.3947944233071312 7 O60502,P33908 2 +Positive regulation of rna splicing 0.4240703693578014 1.1993467403986704 0.2303931477033125 1.0 0.3957038235891872 23 Q14011,P62995,P98179,Q96E39,Q96QD8,P38159,Q13595 7 +Positive regulation of dna methylation dependent heterochromatin assembly 0.5872311773661142 1.1972275233482446 0.2312178848185277 1.0 0.3969140261728962 7 Q9UK61 1 +Paranodal junction assembly 0.4868208804301029 1.1964348791091362 0.2315268969977044 1.0 0.3971803951937747 3 Q16880 1 +I kappab phosphorylation 0.5654155044832472 1.1956113106291777 0.2318482755571356 1.0 0.3975830963043874 5 Q96HY6 1 +T cell mediated immunity 0.5191100089967375 1.195453315053291 0.2319099658705814 1.0 0.3975857235897983 11 O15400,P53634,P04439,P01889,Q9NUQ9 5 +Ribonucleoside triphosphate biosynthetic process 0.402229649025795 1.1944828293121357 0.2322891534547284 1.0 0.3979261314624935 30 P56385,P36542,P24539,P00846,P56134,P06576,O75964,P00403 8 +Ribonucleoside metabolic process 0.5536866079946519 1.1923195326591802 0.2331359784922808 1.0 0.3991698657656695 9 P00813 1 +Angiogenesis involved in wound healing 0.528408086284754 1.1902285243246815 0.2339565848302398 1.0 0.4002638025221473 4 P42785,Q9Y251 2 +Modulation of excitatory postsynaptic potential 0.5643084744423926 1.1900046386809435 0.2340445688594632 1.0 0.4003107027930104 5 P05067 1 +Positive regulation of i kappab kinase nf kappab signaling 0.3846950434715198 1.1882274269655244 0.2347438208614913 1.0 0.4012989943284005 37 Q5T9L3,Q8TB61,P09601,Q8WVQ1,P98194,O43657,Q86UE4,Q9Y3E0 8 +Peroxisomal transport 0.535612575757598 1.1876280415579346 0.234979985058267 1.0 0.4015439652290668 10 Q9Y5Y5,O75381,P40855 3 +Lymphocyte activation 0.3079749888009561 1.1875553612422547 0.235008633303984 1.0 0.4015439652290668 104 P00813,P24390,Q96L92,P31749,P78318,P04439,P11279,P51809,Q9NUQ9,P14174,P04062,P55327,Q9HCL2,Q8WXW3,Q08722,Q96FZ2,P0CG08,P46379,Q92542,P30825,O96005 21 +Negative regulation of gliogenesis 0.6004082876500363 1.186966620072536 0.2352407873099293 1.0 0.4017329104215305 6 P30536 1 +Regulation of blood circulation 0.4092081869592439 1.184154916860434 0.2363517445677532 1.0 0.4033175006063209 28 P00813,P16615,P05023,P09493,P05026,P42892,P10253,O75844,P0DP25 9 +Negative regulation of catabolic process 0.307768535107832 1.1817664876599283 0.2372983685206691 1.0 0.4047238496911231 106 P10619,P49069,Q16850,Q96HY6,Q9H2J4,P35637,O15118,Q9UL15,P31749,P09601,Q99729,O60506,Q08J23,Q92804,P98175,Q14011,P46379,Q07820,P67809,P30536 20 +Adipose tissue development 0.5159806711016972 1.1771312519732369 0.2391431230575231 1.0 0.4067716642670028 11 O15173 1 +Positive regulation of lymphocyte mediated immunity 0.4495313989959651 1.17711978872644 0.2391476977633146 1.0 0.4067716642670028 18 O15400,P04439,P01889,Q96FZ2,Q9NUQ9 5 +Regulation of natural killer cell mediated immunity 0.5983334650103385 1.1769973824883069 0.2391965509946561 1.0 0.4067716642670028 6 P11279,P01889,P04439 3 +Interleukin 12 production 0.5825611778419435 1.1739724242348724 0.2404060711374684 1.0 0.4080293528965176 7 Q08722,P01889 2 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.3863795580760537 1.1726682368214922 0.2409288736716757 1.0 0.4084912586188057 34 P00813,O15400,P53634,P04439,P01889,P10909,Q96FZ2,Q9NUQ9 8 +Golgi to plasma membrane protein transport 0.4264005213677673 1.171437673935486 0.2414228964274332 1.0 0.4089330071946421 20 Q9H4A5,Q13439,Q9H4A6,P41240,P98194,Q4J6C6,O15027,Q9HD26,Q9BZG1 9 +Cellular response to inorganic substance 0.3746889007398299 1.1714071835346065 0.2414351461746684 1.0 0.4089330071946421 45 P46940,Q86YQ8,P31749,O75131,P09601,Q6NUK1,Q99538,P05067,Q14168,P24941,O95831,Q92542,Q14103,P16220,P05198,Q9NQ88,P30536,P55011,P27361 19 +Ribonucleoside triphosphate metabolic process 0.3831103018550987 1.171248778498982 0.2414987936269765 1.0 0.4089330071946421 40 P56385,O60313,P36542,P24539,P00846,Q8IWA4,P56134,P06576,O75964,P00403 10 +Intracellular lipid transport 0.4793122804848908 1.1707836911203358 0.2416857348848728 1.0 0.4090029452354174 15 P50416,O15118,Q96JX3,P61916,O43772,P28288 6 +Negative regulation of glial cell differentiation 0.4409588635691109 1.170720122112472 0.2417112942729309 1.0 0.4090029452354174 2 P35222 1 +Regulation of heart rate 0.4977774395913761 1.17025641065821 0.2418977977257654 1.0 0.4091892872202672 13 P09493,P00813,P0DP25,P16615 4 +Positive regulation of endocytosis 0.4222937696147649 1.1684464165588275 0.242626741205296 1.0 0.4099662890169921 22 P61978,P10909,P50897 3 +Homeostasis of number of cells 0.3357801883888734 1.1670896500841277 0.2431741671222653 1.0 0.4105078085596556 65 P00813,O43251,Q92542,P49069,P04062,P09601,Q9HCL2,P14174,Q9NX40 9 +Alternative mrna splicing via spliceosome 0.3741168149017071 1.1654927494622784 0.2438195934182923 1.0 0.4112822084996155 45 P62995,O43251,P31483,Q07955,Q9UHX1,P23246,Q9UNW9,P52756,P38159,O75525,P98175 11 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.4878092057482658 1.164640507115226 0.2441645399640777 1.0 0.4117589805109951 14 O43657 1 +Protein o linked glycosylation 0.4582675787892115 1.163981199795992 0.244431630727792 1.0 0.4119510508885408 17 Q10472,O60502,Q9H9S5,O43505,Q9Y2G5 5 +Positive regulation of neuron apoptotic process 0.5054238632450848 1.1638978051137745 0.2444654292003112 1.0 0.4119510508885408 12 Q07820,O95831,Q15375 3 +Nuclear pore organization 0.4962376847861033 1.1607500844873295 0.2457435474721965 1.0 0.4137883070684705 13 Q9BTX1,Q9NQC3 2 +Relaxation of muscle 0.5228679716929878 1.1605709973646714 0.2458164056373717 1.0 0.4138055590569001 4 P05023 1 +Regulation of establishment of protein localization 0.2999653587163614 1.157837622562323 0.246930306867628 1.0 0.4153846647428785 151 Q92544,Q9GZP9,O14737,Q16850,P06493,P55786,P27105,O43768,P51572,Q9H4A5,Q5T9L3,Q96KC8,Q8N183,Q9BZL1,Q9GZY8,Q9H4A6,Q9Y282,P49257,Q13438,P18031,Q8N5M9,P50402,P60604,Q14C86,P50416,P53985,Q32P28,P62258,Q66GS9,P98194,P31751,Q9NR31,O43464,Q9UII2,Q9BRT2,P49755,Q13263,Q9Y3B8,Q9C0E2,Q8NE86 40 +Positive regulation of isotype switching to igg isotypes 0.4388872447469752 1.1578065025028337 0.2469430091957587 1.0 0.4153846647428785 2 P43246 1 +Blastocyst formation 0.4955802063319128 1.1566904216193987 0.2473988644252864 1.0 0.4159381548945504 13 P00813 1 +Leukocyte apoptotic process 0.4164592321357575 1.1563848018844696 0.2475237953094669 1.0 0.4159381548945504 24 P00813,P24390,P14174 3 +Regulation of leukocyte proliferation 0.4059101160399893 1.1558547666935093 0.2477405671936956 1.0 0.4161965959794445 28 P00813,P14174,Q9HCL2 3 +Protein catabolic process 0.2926895754589409 1.155042908146233 0.248072855761235 1.0 0.4165430649710372 293 P10619,Q9UBV2,P50897,Q05086,P28074,P49069,Q96PU5,Q16740,P07858,Q9GZP9,P30260,O00231,Q9UMX0,Q13190,P46934,Q16850,Q96HY6,Q9H2J4,P61289,Q9BRG1,P51572,Q9BW61,Q9NUJ1,P31749,Q9UL15,O43633,P53634,Q96K76,Q9BUN8,Q9Y297,Q9UG56,Q8N511,P04062,P33908,Q8TCT9,Q9UL46,P24941,P10909,Q9UJX3,Q9UHG3,Q9Y5X3,O75844,O75503,O14773,Q9UIQ6,O43464,P28072,Q96A33,Q8N2K0,P46379,Q13501,O60502,Q05639,Q9UBS8 54 +Negative regulation of epithelial cell proliferation 0.4464156945014861 1.1547770945652502 0.2481817193187763 1.0 0.4165708312170049 18 Q9Y3B8 1 +Maintenance of protein location 0.3844155920614208 1.1541918881945752 0.2484215075075984 1.0 0.4166294847852734 34 P31749,P24390,O43731,P30536,O43292,O15258 6 +Cytokine production 0.3052325668473932 1.154147940041557 0.2484395217943353 1.0 0.4166294847852734 99 Q99584,P01889,O00571,P04439,P09601,Q9H1D9,Q8IV08,P05067,Q9NUQ9,P14174,P04062,Q9HCL2,P10909,Q8WXW3,Q08722,P49755,P31483,Q9NUD5,P30536 19 +Regulation of receptor binding 0.5211577875243585 1.1514159010498677 0.2495611752376052 1.0 0.4179801842740327 4 P10586 1 +Regulation of atpase coupled calcium transmembrane transporter activity 0.4377034625628959 1.1504277189757204 0.2499677488986382 1.0 0.4183999068267355 2 P54652 1 +Protein localization to phagophore assembly site 0.5927551017116013 1.150191498207505 0.2500650071063104 1.0 0.4183999068267355 6 P53365,Q5MNZ6,Q7Z3C6,Q9Y4P1 4 +Negative regulation of growth 0.3926766118031202 1.1471998938132446 0.251299015460765 1.0 0.4200392496662105 31 P50897,O75489,Q15375,O14681,P22413,O00571,Q9NQC3 7 +Regulation of amyloid precursor protein catabolic process 0.4657507027302872 1.1457509611824923 0.251898211109002 1.0 0.420934330523235 16 P10909,Q9NQC3,O95197,O75298 4 +Er nucleus signaling pathway 0.4656868144942938 1.145320733115177 0.2520763205001248 1.0 0.421125480835522 16 P16615,P57088,O76024,P49841,Q15363,P18031,Q96A33 7 +Extracellular exosome assembly 0.5199881551672969 1.1451547012466154 0.2521450792282134 1.0 0.421133896542649 4 O00560,Q8WUM4,Q99816 3 +Response to salt 0.5552248001222373 1.143993820202337 0.2526261998744101 1.0 0.4218062542415591 5 P07196,Q14103,P09651 3 +Establishment of protein localization to vacuole 0.4226722645163085 1.142798746238881 0.2531221594844113 1.0 0.4221257512067813 20 P10909,Q9BRG1,Q14108 3 +Regulation of reactive oxygen species biosynthetic process 0.5442293453629714 1.141443498727097 0.2536854118186853 1.0 0.4227450546418788 9 Q9BSK2,P00403 2 +Regulation of nik nf kappab signaling 0.4333356651615387 1.138630301494348 0.2548573844293651 1.0 0.4243770354481416 19 O43657 1 +Fatty acid transmembrane transport 0.5597820697608387 1.1380014991804583 0.255119856329371 1.0 0.4244932352670728 8 P50416,P31749,P31751,O43772,P28288 5 +Negative regulation of toll like receptor signaling pathway 0.5177129612673763 1.1329759624557914 0.2572243478541778 1.0 0.4272419489741798 4 Q9NPR9 1 +Long chain fatty acyl coa biosynthetic process 0.574272169122642 1.1326875475293905 0.2573454888250213 1.0 0.4273357627247652 7 Q9UKU0 1 +Centriole centriole cohesion 0.5528351472493864 1.1318899752762177 0.2576806937849349 1.0 0.427486035721783 5 Q66GS9,Q9BV73 2 +Apoptotic signaling pathway 0.298177115594904 1.1287664487725722 0.2589963696243491 1.0 0.4287304687592217 147 Q9UMX0,O14737,P61978,O00571,Q9NQX7,P61289,O95881,P51572,Q9H3K2,P31749,Q9UL15,P45880,P53634,P09601,Q9GZY8,Q96K76,P14174,O60313,Q8N2F6,Q96A26,P10909,Q07812,Q3ZCQ8,O95831,O43464,O95470,Q9NR28,P46379,O43324,Q9Y3B8,O75489,Q07820,O75915 33 +Regulation of endothelial cell migration 0.3946484387930565 1.1272476991163856 0.2596377683977058 1.0 0.4292011033868028 30 P31749,P09601,Q99538,P57105,P78536,P06576,P42785,Q8WTV0 8 +Negative regulation of cell growth 0.4024874079678814 1.1264521398047205 0.259974187828681 1.0 0.4294349930916652 28 P50897,O75489,Q15375,O14681,P22413,Q9NQC3 6 +Cytosolic transport 0.3180729615900887 1.1252002552897942 0.2605041849940712 1.0 0.4302029381873605 72 O15260,O15498,Q13190,Q9BVK6,P20339,O60499,O95249,Q9Y5X3,O75503,O60749,O43752 11 +Negative regulation of fibroblast proliferation 0.5725352448432404 1.124036472555458 0.2609975535075137 1.0 0.4308024053774122 7 P50402,Q71SY5 2 +Nuclear pore complex assembly 0.5409207529158078 1.1236408761323975 0.2611654078381948 1.0 0.4309718303127665 9 Q9BTX1,Q9NQC3 2 +Negative regulation of ion transport 0.4140476245889208 1.1192716042428763 0.263024286028978 1.0 0.4332820304998793 23 Q9UMX0,P21796,P46934,O75915,O95747,P0DP25 6 +Glial cell development 0.406624223912858 1.1154842396539113 0.2646429684594085 1.0 0.4352053219082668 26 Q92542,Q8N3R9,P31751,P05067,P10909,P08670 6 +Establishment of planar polarity involved in neural tube closure 0.4727649496743675 1.1154613436639158 0.2646527748145444 1.0 0.4352053219082668 3 O14641,Q13308 2 +Glycosyl compound metabolic process 0.4007356662606501 1.1113921525845345 0.2663995886773818 1.0 0.4374248152966003 28 Q9NUJ1,P00813,O60725,P04062,P04066,Q9BTY2,P06280 7 +Detection of muscle stretch 0.4311926605504659 1.1098556506358788 0.2670612339661216 1.0 0.4378440071485259 2 P35222 1 +Synaptic vesicle clustering 0.4311926605504659 1.1098556506358788 0.2670612339661216 1.0 0.4378440071485259 2 P35222 1 +Regulation of presynapse organization 0.5477893908082356 1.1063367025610775 0.26858081141066 1.0 0.4393689560923396 5 P05067 1 +Regulation of vesicle mediated transport 0.3012743939162435 1.1052095914832725 0.2690687817395738 1.0 0.4397318443414548 128 Q15907,P50897,Q96PU5,P61978,P30533,P16615,O43633,Q15019,P09601,P20339,P51151,P05067,P11279,Q4J6C6,P51809,P18031,P0DP25,P98194,P31751,Q4KMQ2,P10909,Q08722,Q8N6T3,Q9Y6B6,Q9NR31,Q8WTV0,Q9P2W9,Q12907,P51148,P61020,P49841,P57105,Q9H223,Q9P253,P27361,Q8NBU5 36 +Negative regulation of apoptotic signaling pathway 0.3250073807485557 1.1033199486334715 0.2698882465530117 1.0 0.4406352325762979 68 O00571,P61289,O95881,Q9H3K2,P31749,Q9UL15,P45880,P09601,Q96K76,P18031,Q15233,P14174,O60313,Q8N2F6,P10909,Q07812,O76024,O43464,O75489,Q07820,P49841 21 +Organic hydroxy compound biosynthetic process 0.3550649834136771 1.102947575239132 0.2700499321514775 1.0 0.4407903189896555 51 P16435,P04062,Q14739,Q15125,P00374,O75845,O15269,Q16850,Q15800,Q13510,Q15392,Q14534 12 +Response to hepatocyte growth factor 0.5827890256239446 1.1023047708329796 0.2703291959643208 1.0 0.441137199043999 6 Q99538,P16220 2 +Response to dexamethasone 0.5680518923374083 1.1017084853725 0.2705884267836849 1.0 0.4412333857916046 7 P04062 1 +Hydrogen peroxide metabolic process 0.5366818875909009 1.100833356392309 0.2709691912993726 1.0 0.4416363465591993 9 P00403 1 +Cellular defense response 0.4698046181172298 1.098415960298701 0.2720228962418036 1.0 0.4426986755139326 3 Q9ULC3,P05556 2 +Regulation of glucose import 0.4944543993305947 1.097943029538755 0.2722293669473608 1.0 0.442709268473748 12 P31749,O75298,P31751,P22413,Q16625 5 +Regulation of cell aging 0.4857699833181645 1.0960957101749846 0.2730368917759271 1.0 0.4437841678113077 13 P14174,O75844 2 +Inner ear receptor cell development 0.5668478864943959 1.0957131234191602 0.2732043377645639 1.0 0.4437841678113077 7 P54802 1 +B cell differentiation 0.4760826524502198 1.0901655885397148 0.2756402086410623 1.0 0.4467155808996519 14 P00813,Q07812,P55327 3 +Ubiquitin dependent endocytosis 0.4276413139982305 1.087738337114412 0.2767106381956234 1.0 0.448120707629227 2 Q99816 1 +Lactation 0.4843233265825181 1.0871586904909314 0.2769666836955626 1.0 0.4484254807800033 13 Q99808,Q13505,P16220,Q86UL3,P00403 5 +Regulation of pattern recognition receptor signaling pathway 0.4100138916374873 1.0869944262482092 0.2770392729784983 1.0 0.4484331508975986 23 Q9UMX0,Q9NUD5,Q9NPR9,Q9NQC3,O43657 5 +Paraxial mesoderm development 0.4270494229061919 1.0840533348225194 0.2783411517235932 1.0 0.4500995037291967 2 Q96A65 1 +Columnar cuboidal epithelial cell development 0.5334189518926818 1.0832792129261557 0.2786845090610979 1.0 0.4505445010726017 9 P31749,Q15382,Q9NQ88,Q86UL3 4 +Activation induced cell death of t cells 0.5429095579778844 1.0816326280452628 0.2794158003860192 1.0 0.4516162936539987 5 Q9HCL2 1 +Leukocyte proliferation 0.3677027721595017 1.080452535097709 0.2799407123752757 1.0 0.4523540753271876 44 P00813,P04062,P30825,Q9HCL2,P10909,P14174 6 +Second messenger mediated signaling 0.3969940734325812 1.079201758923592 0.2804977957429286 1.0 0.4528835468664011 28 P00813,P16615,P05026,Q8NE86,O75844,P51572,P0DP25 7 +Negative regulation of endoplasmic reticulum calcium ion concentration 0.5074567063431703 1.078100034760489 0.2809891161276279 1.0 0.4532724111514505 4 P51572 1 +Negative regulation of developmental growth 0.5155101087001631 1.0748955337009258 0.2824215018310043 1.0 0.4550902732231093 10 Q9NQC3,Q15375 2 +Mammary gland epithelium development 0.5154946457596259 1.0748088286454482 0.2824603269422294 1.0 0.4550902732231093 10 P31749,P31751,Q9Y297,Q07812,Q9NQC3 5 +Plasma lipoprotein particle clearance 0.4903657942252692 1.0733575003662728 0.2831107453170474 1.0 0.4560270328540985 12 P09601,P61978,P35610,Q8WTV0,Q92945 5 +Mast cell activation 0.5468141169839039 1.0709400372429687 0.2841963920609103 1.0 0.4571040306683273 8 P09601,Q99584 2 +Response to abiotic stimulus 0.2931037598488117 1.0706370041985342 0.2843326781778625 1.0 0.4571040306683273 225 Q92544,P00813,Q15907,Q9UMX0,Q9BWF3,P05026,Q9BPX6,P46934,P30519,P00846,O00571,P55786,O75306,P52789,P00403,Q9BV73,P31749,P27544,P09601,P22830,Q99538,P05067,Q96K76,P51798,Q9Y487,O75116,Q70UQ0,Q8N511,P04062,Q96A26,P62258,P31751,Q8NBN7,Q07812,Q9Y4P3,O95831,O75844,Q96QD8,O43464,P61421,Q8N2K0,Q14011,Q15555,Q99808,O60884,Q9NXR7,O95202,P49841,P05198,Q14103,Q9NQ88,Q8IXJ6,P30536,O95747,P78536,P08183,P27361 57 +Positive regulation of mrna splicing via spliceosome 0.4446752712272187 1.069524430140589 0.2848334266207462 1.0 0.4577350811881407 17 Q14011,P62995,P98179,P38159,Q13595 5 +Mitochondrial electron transport nadh to ubiquinone 0.4005151762261777 1.0644679365055505 0.2871167720312448 1.0 0.460683356726025 26 O95298,Q9Y6M9,P56556,P09622,O75489,O43674,P03886,O95168,P51970,O75438,O43676,O75306,O75208 13 +Epidermal cell differentiation 0.3717857879613476 1.0632581701384156 0.2876648890994344 1.0 0.4613388138942398 37 Q9Y3B8,Q13510,Q16739,Q8NEY8 4 +Import across plasma membrane 0.4105488079606586 1.061886475833839 0.2882872254232085 1.0 0.4622247144158139 21 P31749,P05023,Q15041,P05026,P30825,P31751,Q9Y289,O75915,P55011,P54709,Q15758 11 +Low density lipoprotein particle clearance 0.4962417144633597 1.0614988499979314 0.2884632552633299 1.0 0.4623947742021216 11 P09601,Q8WTV0,P61978 3 +Nucleoside triphosphate biosynthetic process 0.3721201592056404 1.056034154221804 0.2909526111508436 1.0 0.4655175778550156 36 P56385,P36542,P24539,P00846,P56134,P06576,O75964,P00403 8 +Dopaminergic neuron differentiation 0.4622749180355097 1.055092457658134 0.2913830411937015 1.0 0.4659950172050078 3 P49841 1 +Neuron projection regeneration 0.4951361871071332 1.055024007558809 0.2914143450004989 1.0 0.4659950172050078 11 P07196,P30536,Q96G23,P00374 4 +Amyloid beta clearance by transcytosis 0.572656293924981 1.05364893235157 0.2920436774571415 1.0 0.4668884045269106 6 Q15907,P20339 2 +Gliogenesis 0.3300640952673986 1.050219879636756 0.2936170316183581 1.0 0.4689499666422738 63 P31749,Q7Z4L5,Q92542,P04062,Q96N66,Q15382,Q8N3R9,P31751,P05067,P10909,P08670,P30536,Q96G23,Q8IXJ6,Q9NQC3,P06493,O75306,O94901 18 +T cell activation 0.331434876704747 1.046902525916935 0.2951445367747132 1.0 0.4707551557692757 62 P00813,P31749,P24390,Q92542,P04439,P04062,P30825,Q9HCL2,Q08722,Q07812,P0CG08,Q9NUQ9,O96005 13 +Regulation of hydrolase activity 0.2946239200801076 1.0466138783824952 0.2952776984003233 1.0 0.4707989156243638 181 P50897,Q14108,O14737,P07858,Q15375,Q96HY6,O00571,P61289,O15031,P51572,P31749,P16949,P78318,P16435,Q15041,P05067,Q96K76,P07602,Q14C86,P0DP25,Q9BXK5,Q96A26,P31751,Q9UL46,Q15363,O95831,O43464,Q15392,Q9NR28,P49755,Q92542,Q15555,Q9NZJ7,Q9Y3B8,O75915 35 +3 utr mediated mrna destabilization 0.57116004164376 1.0464689437183918 0.2953445762110172 1.0 0.4707989156243638 6 Q14103 1 +Nadp metabolic process 0.4509042725006724 1.0457217978442284 0.2956894958064788 1.0 0.4712203383883713 16 Q13423,Q9BQG2,P48735 3 +Angiotensin activated signaling pathway 0.5008845079797063 1.0429728493258668 0.2969608676272823 1.0 0.4722363749154737 4 O75116 1 +Mononuclear cell differentiation 0.3584076364148709 1.042186682623002 0.2973251361245164 1.0 0.4725882214158078 47 P00813,P24390,P04062 3 +Cellular response to unfolded protein 0.3724045108595807 1.0409197661633491 0.2979127871842977 1.0 0.4732946179088999 34 Q9GZP9,P57088,O76024,P05198,Q96JB5,Q92905,Q9BUN8,Q9Y4P3,Q96HY6,Q15363,Q13438,Q07812,P18031,P0DMV9,P48723 15 +Cerebral cortex radially oriented cell migration 0.5404848208151996 1.038233087109537 0.2991615520765824 1.0 0.4750501436026269 8 Q00535,P35222,Q96N66,Q9NQC3,P07942,O94901 6 +Telencephalon glial cell migration 0.5404848208151996 1.038233087109537 0.2991615520765824 1.0 0.4750501436026269 8 Q00535,P35222,Q96N66,Q9NQC3,P07942,O94901 6 +Positive regulation of establishment of protein localization 0.2979755176131757 1.0359340983385843 0.300232888471412 1.0 0.476319964566013 100 Q92544,Q9H4A5,Q5T9L3,Q9NR31,P49755,O14737,Q9Y3B8,Q9GZY8,Q9H4A6,Q9Y282,P31751,P55786,P27105,P50402,O43464,P51572 16 +B cell receptor signaling pathway 0.4587467124779565 1.034813820078294 0.3007558675254049 1.0 0.4770087661328057 3 Q07812 1 +Regulation of core promoter binding 0.4190588931636649 1.0343510579816615 0.3009720756164231 1.0 0.4771641609150874 2 P35222 1 +Regulation of neuron projection arborization 0.4992596979567537 1.0342950658800127 0.3009982428287183 1.0 0.4771641609150874 4 Q9UPN3,Q9HCE1,O14641 3 +Cerebral cortex cell migration 0.4831675018159153 1.0300866164473967 0.3029693472456627 1.0 0.4793690246460581 12 Q00535,P35222,Q96N66,P00533,Q9NQC3,P07942,O94901 7 +Amyloid beta clearance 0.4748499721309879 1.0286470942039754 0.3036455393090986 1.0 0.4802089900200605 13 P10909,Q16850,P20339 3 +Mast cell activation involved in immune response 0.5531246990778543 1.027427121769929 0.3042193858703035 1.0 0.4807713824047909 7 P09601,Q99584 2 +Regulation of apoptotic signaling pathway 0.2973979761247258 1.0267051666188054 0.3045593157076869 1.0 0.4809571956817266 100 Q9UMX0,P61978,O00571,Q9NQX7,P61289,O95881,P51572,Q9H3K2,P31749,Q9UL15,P45880,P53634,P09601,Q96K76,P18031,O75569,Q15233,P14174,O60313,Q8N2F6,P10909,Q07812,O76024,O43464,O43324,O75489,Q07820,P49841,P23246 29 +Nucleoside phosphate catabolic process 0.4182435165556504 1.026547521998838 0.3046335756061156 1.0 0.4809571956817266 19 P00813,Q9BQG2,Q9H773 3 +Negative regulation of transport 0.3201707410751316 1.0264898488870615 0.3046607460403674 1.0 0.4809571956817266 83 P00813,P31749,Q9GZP9,Q9UMX0,P09601,P21796,P31751,P05067,P46934,Q16850,Q08722,P22413,O75915,O95747,Q8N5M9,P0DP25 16 +Cellular lipid catabolic process 0.3117100046594346 1.0259734575516617 0.3049040953318815 1.0 0.4810963218937045 73 O95470,P50897,P06280,Q15067,Q8WTV0,P17900,Q9BWD1,P04062,Q8NHP8,Q99735,P31751,P04066,O15254,P06865,O75874,Q13510,Q8N2K0 17 +Regulation of er associated ubiquitin dependent protein catabolic process 0.4972419101805033 1.0235227293187437 0.3060607588124227 1.0 0.4825275655990699 4 Q9UMX0 1 +Mononuclear cell migration 0.3903322609194328 1.0218248638017158 0.3068637991680076 1.0 0.4833324234273982 28 P31749,P04062,Q99538,P05067,Q4KMQ2,Q5JRA6,Q08722,O95747,P78536,P27361 10 +Regulation of neuronal synaptic plasticity 0.5366001014053199 1.018172742929237 0.3085958704240037 1.0 0.4852510367909209 8 P05067 1 +Positive regulation of leukocyte cell cell adhesion 0.3919902627961026 1.0136776234633234 0.3107366047871993 1.0 0.4882687163667618 27 P00813,P30825,Q9HCL2,Q08722,Q9NUQ9 5 +Neural retina development 0.5642056942761698 1.013120164876695 0.3110027676013618 1.0 0.4884546794385457 6 Q15555,P54802 2 +Plus end directed organelle transport along microtubule 0.4155075466114322 1.012295284106134 0.3113968890219156 1.0 0.488841339559582 2 P33176 1 +Lipid catabolic process 0.3176495420865816 1.0111702707065593 0.3119349421290638 1.0 0.4894534740102048 86 P50897,Q9BWD1,Q8N2A8,O75874,P17900,Q13510,Q9H6V9,O15254,Q15067,P04062,Q8NHP8,Q99735,P31751,Q8WTV0,Q8N2K0,O95470,P04066,P06865,P06280 19 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.5628391492222298 1.0065721455640142 0.3141404256052866 1.0 0.4921348944317575 6 P14174 1 +Negative regulation by host of viral process 0.4538188277087048 1.0065208315403684 0.3141650960217257 1.0 0.4921348944317575 3 Q9H1E3,P17980 2 +Leukocyte differentiation 0.3212794882412786 1.0049274134184023 0.3149318031541859 1.0 0.4931021765093614 66 P00813,P24390,P04062,Q14739,P55327,P01889,P16220,P05067,Q07812,O96005,P0CG08,Q8N5M9 12 +Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 0.4533882086362643 1.0040503966292862 0.3153543227403377 1.0 0.4936467832759099 3 Q9UII2 1 +Negative regulation of macroautophagy 0.4624777244233203 1.0037615129073014 0.315493579486696 1.0 0.4937478254386866 14 P09601,P31749,Q9NQ88,O15118 4 +Rna capping 0.4140278188813342 1.0031130203819782 0.3158063331776906 1.0 0.4941202784023099 2 Q53F19 1 +Myelin assembly 0.531315365165616 0.990905735370756 0.3217316115350188 1.0 0.5006649919083918 8 Q8N3R9,Q9NR77 2 +Neuron projection guidance 0.3892816836910564 0.9906852752122812 0.3218392833415437 1.0 0.5007146477411165 27 O00264,P35613,P42892,P05067,O15031,Q9UNW9 6 +Mitotic nuclear membrane organization 0.5455952077795825 0.9900221885068105 0.3221632738268483 1.0 0.5010129764706187 7 Q9H6H4,Q6NUK4,Q86XL3 3 +Regulation of aspartic type peptidase activity 0.490915543023197 0.9897837030710582 0.3222798521056838 1.0 0.5010129764706187 4 P49755 1 +Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process 0.490915543023197 0.9897837030710582 0.3222798521056838 1.0 0.5010129764706187 4 P49755 1 +Cell communication by electrical coupling 0.5310761879282266 0.9896724035507976 0.3223342678095129 1.0 0.5010129764706187 8 P05023,P0DP25 2 +Regulation of toll like receptor signaling pathway 0.4838748282066388 0.9891189283630863 0.3226049576535048 1.0 0.5011979701767779 11 Q9UMX0,Q9NQC3,Q9NPR9 3 +Lymphocyte activation involved in immune response 0.3936690786744746 0.988421299180371 0.3229463605118332 1.0 0.5014925978906734 25 P00813 1 +Regulation of sequestering of triglyceride 0.450562462995861 0.9878478553305984 0.3232271664163586 1.0 0.5018107453243397 3 Q9BXB4,Q9BZF1 2 +Type b pancreatic cell development 0.5240399594070738 0.9862759323850028 0.3239977267903162 1.0 0.5024725055915178 5 P31749,Q15382 2 +Crd mediated mrna stabilization 0.5153123253674184 0.9859791545907394 0.3241433421427238 1.0 0.5024725055915178 9 P67809,P11940,Q14103,O60506 4 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.5153123253674184 0.9859791545907394 0.3241433421427238 1.0 0.5024725055915178 9 P67809,P11940,Q14103,O60506 4 +Endoplasmic reticulum plasma membrane tethering 0.4499703966844497 0.984454991840541 0.3248918508418343 1.0 0.5032130869964104 3 A0FGR8,Q9BSJ8 2 +Endoplasmic reticulum localization 0.4499703966844497 0.984454991840541 0.3248918508418343 1.0 0.5032130869964104 3 A0FGR8,Q9BSJ8 2 +Regulation of neuron projection development 0.3139375017214242 0.980292458515992 0.326941776268681 1.0 0.5057954586516182 80 P07196,P31749,Q9UL15,Q05086,Q9NR77,Q14108,Q96PU5,Q32P28,P46934,P08670,Q96G23,Q9NQX7,Q9NZQ3,Q9NQC3,O15031,P10586,Q9UQB8 17 +Regulation of endoplasmic reticulum unfolded protein response 0.4984124897289098 0.97912264887356 0.3275193820030539 1.0 0.5064519409588638 10 P57088,Q92905,Q07812,Q96HY6,P18031 5 +Astrocyte development 0.5432979585568034 0.9786223095270816 0.32776663189731 1.0 0.5065972100583073 7 P05067 1 +Negative regulation of release of cytochrome c from mitochondria 0.5287671221985537 0.9777691544143068 0.3281885100673638 1.0 0.5070414534727332 8 P10909,P31749,Q9H3K2 3 +Microtubule anchoring at microtubule organizing center 0.5562485213537236 0.975020704670708 0.3295499897722393 1.0 0.5085542975306032 6 P49841,Q8TD16 2 +Negative regulation of lipid localization 0.4881002252498491 0.9747894252641476 0.3296647236380625 1.0 0.5085542975306032 4 P31751 1 +Regulation of response to biotic stimulus 0.3132920475709299 0.974508339665392 0.3298042003530947 1.0 0.5085542975306032 69 P01889,Q16543,O43657,Q7Z739,P04439,Q9H1D9,Q8WXF1,P11279,P18031,Q8IZ81,Q15233,Q9NZ08,P14174,O75844,Q9NUD5,Q9NQ88,Q8IXJ6,P23246,Q9BY67,Q96PK6,P27361 21 +Regulation of response to external stimulus 0.2897206055143854 0.9743570303683052 0.3298792969456341 1.0 0.5085542975306032 145 P00813,Q13277,Q16543,P01889,P80303,O43657,Q7Z739,P53634,P04439,Q99538,Q9H1D9,Q8WXF1,Q9UNH7,P05067,P11279,P51809,P18031,Q9NUQ9,Q8IZ81,Q15233,Q9NZ08,P14174,P04062,Q99735,Q9UMX5,Q9Y251,Q08722,Q96G23,O75844,P10586,Q8N2K0,Q8NE86,Q9NUD5,Q8IXJ6,O95747,P23246,P78536,Q9BY67,Q9UNW9,Q96PK6,P27361 41 +Glucose import 0.4575318216250638 0.9723821802951093 0.3308604536700632 1.0 0.5098290366764859 14 P31749,O75298,P31751,P22413,Q16625 5 +Positive regulation of immune system process 0.2947301620752682 0.971285413000328 0.3314061706499285 1.0 0.5104319230541546 121 P00813,Q99623,P01889,Q07666,P31749,P53634,P04439,P09601,Q99538,Q9H1D9,Q8WXF1,P05067,P11279,P51809,Q9NUQ9,Q15233,P14174,Q9HCL2,P10909,Q07812,Q08722,Q96FZ2,P46379,O15400,Q8NE86,P30825,Q9NUD5,P16220,Q5JRA6,O95747,P23246,P78536,Q9BY67,Q96PK6,P27361 35 +Neuron differentiation 0.286372783952898 0.9704637125198868 0.3318154041455405 1.0 0.5109431514440536 240 P07196,Q13277,P50897,Q05086,Q14108,Q96PU5,P42892,P46934,Q16739,Q9NQX7,O15031,P31749,Q9UL15,P16949,O43251,Q9NR77,O00264,P35613,P05067,P54802,Q32P28,P04062,Q8N3R9,P08670,Q96G23,Q9NQC3,O75503,Q8WUJ1,O43464,P10586,O14949,Q9UQB8,Q15555,Q9NZJ7,Q9Y6M7,P00374,P30536,Q9NZQ3,Q9UNW9 39 +Aging 0.3128062381750308 0.9680276725209424 0.3330305496128256 1.0 0.5119095117454937 69 P04062,P05067,P00846,P30536,O75844,O43464,P14174 7 +Positive regulation of cellular amide metabolic process 0.3184184244332846 0.96796344421107 0.3330626267976431 1.0 0.5119095117454937 66 Q14011,P98179,P67809,Q9Y2R0,P08670,O15031,Q567V2,O60506 8 +Regulation of immune effector process 0.3566012090232422 0.966321844000607 0.3338831588516973 1.0 0.5130513361662096 44 O15400,P04439,P09601,P01889,P11279,Q08722,Q96FZ2,Q9NUQ9,P14174 9 +Pyridine containing compound biosynthetic process 0.5538950643275689 0.963766922544629 0.3351627937220651 1.0 0.5144196246421571 6 P43490 1 +Positive regulation of mitotic cell cycle spindle assembly checkpoint 0.4859342611785529 0.963263193617098 0.3354154591752352 1.0 0.5146878963754654 4 Q5JVF3,P12270,Q13257 3 +Vascular associated smooth muscle cell proliferation 0.4954055158354468 0.9623106045569552 0.3358936036532864 1.0 0.515233175569612 10 P09601 1 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.4713621006628137 0.9592137123715168 0.3374510939503521 1.0 0.5173004240125283 12 P61978,P14174 2 +Intraciliary transport 0.5101551454893214 0.9583265028079876 0.3378981436621617 1.0 0.5176842796058871 9 Q7Z4L5,O43805,Q8NCM8 3 +Regulation of lipid transport 0.3971658780228737 0.9575562457278582 0.3382865713949345 1.0 0.5181311588294606 21 P30536,P14174,P31751,O15260 4 +Cellular hyperosmotic response 0.5522071899733461 0.955700543987866 0.3392235476048193 1.0 0.5187247631004746 6 O95202 1 +Regulation of plasma lipoprotein particle levels 0.4544871890555981 0.9530806277827936 0.3405492206129015 1.0 0.5203907049781887 14 P09601,P61978,P35610,Q8WTV0,Q92945 5 +Apoptotic dna fragmentation 0.5166437627830274 0.949018937066897 0.3426109807568736 1.0 0.5225919093834382 5 Q07812,O95831 2 +Positive regulation of translation 0.3250323232479408 0.9487923020907196 0.3427262578111338 1.0 0.5225919093834382 61 Q14011,P98179,P67809,Q9Y2R0,P08670,O15031,Q567V2 7 +Positive regulation of leukocyte chemotaxis 0.4537374955478667 0.948330034393964 0.3429614654409043 1.0 0.5226413634388025 14 Q8NE86,Q99538,O95747,P78536,P27361 5 +Regulation of mononuclear cell migration 0.3958684536710127 0.9474467114273076 0.3434111981177032 1.0 0.523114167069305 21 P31749,Q99538,P05067,Q5JRA6,Q08722,O95747,P78536,P27361 8 +Regulation of oxidative phosphorylation 0.4927349766047781 0.9473909357232884 0.3434396082484059 1.0 0.523114167069305 10 P14406 1 +Positive regulation of membrane protein ectodomain proteolysis 0.44345766725874 0.9471847912280764 0.3435446238425719 1.0 0.523153552759345 3 O43847,Q9Y5X1 2 +Notch signaling pathway 0.4172019777979004 0.9450556722202118 0.3446304543772729 1.0 0.5242942391963471 18 Q9UBV2,Q92542,P57105,P05067 4 +Regulation of bone mineralization 0.5204429447074288 0.934920065659934 0.349829495339935 1.0 0.5299159144399794 8 P22413,O75844 2 +Positive regulation of protein catabolic process in the vacuole 0.4410894020130244 0.933657963969784 0.3504803551514592 1.0 0.5303583073900761 3 Q07954,P98164 2 +Very low density lipoprotein particle assembly 0.4027818881325921 0.9335123084471356 0.350555518403655 1.0 0.5303583073900761 2 P35610 1 +Regulation of viral entry into host cell 0.5475555555555581 0.93349256857631 0.350565705641408 1.0 0.5303583073900761 6 P07237,Q92692,O60493,P19474,Q12899 5 +Positive regulation of smooth muscle cell proliferation 0.5201555147050494 0.9334424786738388 0.3505915565895479 1.0 0.5303583073900761 8 P09601 1 +Cell proliferation in forebrain 0.5135408699889487 0.9334165828386384 0.3506049216711551 1.0 0.5303583073900761 5 Q15058,Q15154 2 +Cell migration involved in sprouting angiogenesis 0.5052982183637649 0.932320681065721 0.3511708228905092 1.0 0.5307312985326723 9 P09601 1 +Cellular response to arsenic containing substance 0.5047056667156644 0.929150718388503 0.3528109831135844 1.0 0.5322386219381987 9 P09601,Q96QD8 2 +Polyol metabolic process 0.3919613659209064 0.9289294458712104 0.3529256516829369 1.0 0.5322386219381987 22 Q9NX62,P04062,P00374,O15269,Q10713,Q13510 6 +Regulation of heart contraction 0.384294288763127 0.9288371224615738 0.3529735027924232 1.0 0.5322386219381987 26 P00813,P16615,P05023,P09493,P05026,P10253,O75844,P0DP25 8 +Blood vessel endothelial cell migration 0.388201374097668 0.9269879802286128 0.3539327750469425 1.0 0.5335398984363247 24 P09601,Q8WTV0 2 +Positive regulation of protein targeting to membrane 0.4732126525975084 0.9268624597457517 0.353997950468041 1.0 0.5335398984363247 11 P31751,P27105 2 +Response to salt stress 0.518655943019803 0.9257360329506066 0.3545831771521515 1.0 0.5339348867164659 8 O95202,Q9BPX6 2 +Proximal distal pattern formation 0.439643673721144 0.9254079867583132 0.3547537259231328 1.0 0.5340700169990853 3 O95747 1 +Regionalization 0.3789382400560461 0.92360028825471 0.3556944637105421 1.0 0.5350593337553963 28 Q5T9L3,Q15363,Q8N2A8,O95747,Q9Y2W6,Q9UK61 6 +Positive regulation of type i interferon mediated signaling pathway 0.4393132030787474 0.9235230151969882 0.3557347121381768 1.0 0.5350593337553963 3 Q9NZI8,Q7Z434 2 +Regulation of sodium ion transport 0.3927153701704793 0.9228868551667012 0.3560661714691702 1.0 0.5354360244003972 21 P31749,P05023,Q96PU5,P05026,P46934,O95747,P54709,P27105 8 +Negative regulation of translational elongation 0.401006214856476 0.9225582664824244 0.3562374527210816 1.0 0.5355167605652126 2 P49458 1 +Cytoplasmic pattern recognition receptor signaling pathway 0.4234676017625038 0.9221877541016558 0.3564306495526708 1.0 0.5355284586011827 17 O43657 1 +Myeloid leukocyte activation 0.3874481793209624 0.9208727650139008 0.3571168592574731 1.0 0.5363668844441508 24 P53634,Q99584,P09601,P05067,P10909,P14174 6 +Terpenoid metabolic process 0.3909273522933034 0.9207669036892374 0.3571721377574077 1.0 0.5363668844441508 22 P51648,Q9HB40 2 +Odontogenesis of dentin containing tooth 0.5174619672064122 0.9196030188663143 0.3577802485750645 1.0 0.5367922049563226 8 P35613,Q6P4Q7 2 +Regulation of synapse structure or activity 0.358560199779894 0.9175815286197492 0.3588379919246833 1.0 0.5378578622675362 39 P50897,Q05086,O00264,Q9BQT9,P46934,P05067,Q9UQB8 7 +Response to acid chemical 0.3904643047299275 0.9171121132728968 0.3590838941572751 1.0 0.5378578622675362 22 Q9UQB8,Q9P2J5,Q14103,Q6IAA8,Q99729,O95831,Q15388,Q9UHA4 8 +Regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.4482918181235628 0.913851917340412 0.3607946618468536 1.0 0.5399664674243332 14 P31749,Q9UL15,Q9UMX0,Q07820,P23246,O43464 6 +Purine nucleoside diphosphate biosynthetic process 0.4758661533905768 0.9098147906392302 0.36292019300204 1.0 0.5419203695324181 4 P54819,P00568,P27144 3 +Adp biosynthetic process 0.4758661533905768 0.9098147906392302 0.36292019300204 1.0 0.5419203695324181 4 P54819,P00568,P27144 3 +Regulation of catabolic process 0.2786642880602722 0.9086850847447376 0.3635163794921645 1.0 0.542687994593114 323 P10619,Q05086,Q9UMX0,Q14108,P49069,Q96PU5,Q13190,P21796,P46934,O15269,Q15024,Q16850,Q96HY6,Q9H2J4,O75874,P61289,P35637,P51572,Q9BW61,O15118,Q9UL15,P31749,Q969T7,P27544,P53634,P09601,P05067,Q9Y297,P07602,Q13151,Q99729,Q9BXS4,O60506,Q86UE4,Q92945,Q9Y487,P07910,P50416,Q08J23,Q92804,P04062,P31751,P24941,Q93050,P08670,P10909,Q9UL46,O95831,Q9Y5X3,O75844,Q07812,Q8WTV0,O43464,P98175,Q9NZ45,Q14011,P61421,P46379,Q9NZJ7,Q07820,P67809,Q14103,O43242,Q9NQ88,P30536,Q05639,Q9UBS8 67 +Phosphatidylinositol 3 kinase signaling 0.4214310672048719 0.9080686221617102 0.3638419672448534 1.0 0.5427034965433915 17 P31749,Q05086,P46934,Q10713,Q8NDZ4 5 +Amine transport 0.5007088450935527 0.9077865606865744 0.3639910001967636 1.0 0.5427034965433915 9 Q15041,Q7L0J3 2 +Negative regulation of cytokine production 0.3699381061851721 0.907266452496196 0.3642659100709275 1.0 0.5428260202161804 30 P09601,P04062 2 +Regulation of body fluid levels 0.3280290257012634 0.9062420574215148 0.364807746706947 1.0 0.5433709260346303 56 P00813,P16949,Q99808,P04062,Q13505,P38435,Q9Y3B8,Q9Y251,P16220,Q86UL3,Q86YV9,Q9BWH2,Q16739,P49257,P52789,P00403 16 +Homologous chromosome segregation 0.4695609171913381 0.90558723708793 0.3651543666338839 1.0 0.5436596551212748 11 Q9BTX1,P46379,Q92791 3 +Positive regulation of lipase activity 0.4996026229173949 0.9018792278590976 0.3671210268872218 1.0 0.5454817595992916 9 Q99623,P18085,P00533,Q9Y263,P40616 5 +Positive regulation of phosphoprotein phosphatase activity 0.5070644581653709 0.900913748328812 0.3676341807492531 1.0 0.5458760504542381 5 P0DP25 1 +Regulation of receptor mediated endocytosis 0.3845995799844796 0.8977518890885572 0.3693178391242797 1.0 0.5476377829868443 24 P10909,P50897,P05067 3 +Negative regulation of dephosphorylation 0.4287292163007044 0.8965146248653777 0.3699779729258248 1.0 0.5483186034865998 16 O75116,P62942,P46940,O95429,P62258,P49841,O43768 7 +Eye morphogenesis 0.4985416767718635 0.8962161629787146 0.3701373248998427 1.0 0.5483608115362163 9 Q15555,Q8NBN7,Q07812,Q9P273,P54802 5 +Protein localization to cytoplasmic stress granule 0.526602279050728 0.8960104443089704 0.3702471851027713 1.0 0.5483903144716106 7 P67809,P31483 2 +Mammary gland epithelial cell proliferation 0.5255858481621759 0.89099759519178 0.3729304603595409 1.0 0.5516416518493885 7 Q9Y297,Q07812,Q9NQC3 3 +Lipid translocation 0.5118520215971856 0.8908247520028794 0.3730231940691466 1.0 0.5516416518493885 8 Q96AA3,P08183,Q7Z3C6,Q4KMQ2 4 +Regulation of nervous system process 0.4445489483855019 0.8901900718554072 0.3733638347111201 1.0 0.5516416518493885 14 O75116,P53634,P04062,P05067,O75746,Q9UQB8 6 +Positive regulation of tissue remodeling 0.433392539964497 0.8898094554284489 0.3735682085726375 1.0 0.5516416518493885 3 Q08209,O75116 2 +Regulation of connective tissue replacement 0.433392539964497 0.8898094554284489 0.3735682085726375 1.0 0.5516416518493885 3 Q08209,O75116 2 +Positive regulation of connective tissue replacement 0.433392539964497 0.8898094554284489 0.3735682085726375 1.0 0.5516416518493885 3 Q08209,O75116 2 +Connective tissue replacement 0.433392539964497 0.8898094554284489 0.3735682085726375 1.0 0.5516416518493885 3 Q08209,O75116 2 +Aortic valve morphogenesis 0.4333925399644964 0.8898094554284464 0.3735682085726388 1.0 0.5516416518493885 3 O75116,O94813 2 +Positive regulation of amyloid beta clearance 0.4333925399644789 0.8898094554283463 0.3735682085726926 1.0 0.5516416518493885 3 Q07954,P30533 2 +Leukocyte mediated immunity 0.3379582621551349 0.888280341155661 0.3743899716705181 1.0 0.5525554539460595 50 O15400,P53634,Q99584,P09601,P04439,P01889,P10909,P11279,Q96FZ2,Q9NUQ9,P51809,Q8N5M9 12 +Feeding behavior 0.5107198458516898 0.8850250234467062 0.3761431352940794 1.0 0.554430987362396 8 P50416,Q9GZP9,P05067 3 +Regulation of lymphocyte mediated immunity 0.387834121182149 0.8848997893718323 0.3762106816422625 1.0 0.554430987362396 21 O15400,P04439,P01889,Q96FZ2,Q9NUQ9 5 +Substantia nigra development 0.4180749018878776 0.8848203558040575 0.3762535288731743 1.0 0.554430987362396 17 O75489,P62258,P24539,Q8IXJ6,O15027,P0DP25 6 +Roundabout signaling pathway 0.3947913583900658 0.8843129192912381 0.3765273160785893 1.0 0.554430987362396 2 O94813 1 +Regulation of vascular associated smooth muscle contraction 0.3947913583900629 0.88431291929122 0.3765273160785991 1.0 0.554430987362396 2 P20020 1 +Methionine biosynthetic process 0.4708647328319398 0.88335740889714 0.3770431949446284 1.0 0.554736971368889 4 Q9BV57 1 +Methionine metabolic process 0.4708647328319398 0.88335740889714 0.3770431949446284 1.0 0.554736971368889 4 Q9BV57 1 +Chondrocyte differentiation involved in endochondral bone morphogenesis 0.3944954128440434 0.8824956619237676 0.3775088246526508 1.0 0.5552984246893766 2 P08133 1 +Pyridine nucleotide metabolic process 0.5033068212394535 0.882099232944624 0.3777231469959075 1.0 0.5554373231138104 5 P43490 1 +Trophoblast cell migration 0.4319123741859164 0.881399300696696 0.3781017360397429 1.0 0.5557994602950759 3 Q7Z739,Q07021 2 +Sensory perception 0.353839110330968 0.8798716203905544 0.3789288603036991 1.0 0.5567116519396031 38 Q9Y6M9,O43924,O60313,P50897,Q9Y5L4,Q14108,Q15555,O95677,Q6P4Q7,P07686,Q9H6K4,O76024,Q9Y5J7,O75569,P27361,Q9Y5J9,Q9BV73 17 +Receptor localization to synapse 0.450542983080007 0.8789474676445765 0.3794297597794331 1.0 0.5571320334108584 13 Q13277,O15400,P57105 3 +Estrogen metabolic process 0.5025261901719473 0.8781950235246555 0.3798378921909622 1.0 0.5575475020786906 5 Q53GQ0,O95470 2 +Progesterone receptor signaling pathway 0.5023564445700599 0.8773462751281031 0.380298584682442 1.0 0.5579119525341308 5 P46934 1 +Regulation of dna methylation dependent heterochromatin assembly 0.508967309689828 0.8760532590393205 0.3810010810371138 1.0 0.5586945073384258 8 Q9UK61 1 +Negative regulation of peptidase activity 0.3519501518264727 0.8753703808827455 0.381372410421108 1.0 0.558867020060555 41 P31749,P49755,P16435,Q9Y3B8,Q15041,P07858,P05067,Q96K76,O00571,Q15392 10 +Fatty acid transport 0.4073118031631166 0.8742182741686669 0.3819993960044865 1.0 0.5593106745417729 18 P50416,P31749,O43808,P31751,O43772,P28288,P14174 7 +Regulation of cd4 positive alpha beta t cell differentiation 0.3930156851139486 0.8734151812762811 0.3824368192244236 1.0 0.5593106745417729 2 P09429 1 +Negative regulation of cd4 positive alpha beta t cell differentiation 0.3930156851139486 0.8734151812762811 0.3824368192244236 1.0 0.5593106745417729 2 P09429 1 +Neutrophil homeostasis 0.3930156851139486 0.8734151812762811 0.3824368192244236 1.0 0.5593106745417729 2 P09429 1 +Negative regulation of alpha beta t cell differentiation 0.3930156851139486 0.8734151812762811 0.3824368192244236 1.0 0.5593106745417729 2 P09429 1 +Neutrophil clearance 0.3930156851139486 0.8734151812762811 0.3824368192244236 1.0 0.5593106745417729 2 P09429 1 +Negative regulation of interleukin 8 production 0.3930156851139459 0.8734151812762656 0.382436819224432 1.0 0.5593106745417729 2 Q6GQQ9 1 +Regulation of lipid metabolic process 0.318867554041111 0.872887838173061 0.3827242158555244 1.0 0.5595596062360605 61 P05023,O75874,Q13510,Q92604,P31749,P16435,P07602,P61916,P83111,P50416,P31751,Q8WXW3,Q96G23,O75844,Q8WTV0,Q9NZJ7,Q96N66,P16220,P30536,Q9H6K4,Q05639 21 +Mechanoreceptor differentiation 0.4940919184376531 0.8724927968261053 0.3829395960657431 1.0 0.5596744339669386 9 P54802 1 +Regulation of mitochondrial membrane permeability involved in apoptotic process 0.4790773278124539 0.8713037241859097 0.3835883375663671 1.0 0.5604986343082291 10 Q07812,Q9UII2,P45880 3 +Regulation of retinal ganglion cell axon guidance 0.3924237940219096 0.8697857582346382 0.3844174958570243 1.0 0.5607121641549514 2 O94813 1 +Autonomic nervous system development 0.3924237940219068 0.8697857582346211 0.3844174958570336 1.0 0.5607121641549514 2 P35222 1 +Cranial ganglion development 0.3924237940219068 0.8697857582346211 0.3844174958570336 1.0 0.5607121641549514 2 P35222 1 +Sympathetic ganglion development 0.3924237940219068 0.8697857582346211 0.3844174958570336 1.0 0.5607121641549514 2 P35222 1 +Sympathetic nervous system development 0.3924237940219068 0.8697857582346211 0.3844174958570336 1.0 0.5607121641549514 2 P35222 1 +Outflow tract septum morphogenesis 0.3924237940219067 0.8697857582346203 0.3844174958570341 1.0 0.5607121641549514 2 P98164 1 +Regulation of stress granule assembly 0.4298401420959118 0.8696384154531517 0.3844980372144408 1.0 0.5607121641549514 3 Q13131,Q9UN86 2 +Embryonic appendage morphogenesis 0.4485955328845183 0.8670045120944637 0.3859395374575123 1.0 0.5624419852385224 13 Q07812,O95747,Q9NX62,P42892 4 +Viral protein processing 0.5069353744786524 0.8656604479547813 0.3866763959643973 1.0 0.5632674236122331 8 P61009,Q10472,P49841 3 +Response to calcium ion 0.3763795763774784 0.8626984685547436 0.388303274626613 1.0 0.5651390314924655 26 O75131,O75340,Q92542,P46940,Q6NUK1,Q99538,Q14103,P46934,P50995,Q86YQ8,O75746,O43865,P0DP25 13 +Interleukin 6 production 0.447736794572953 0.8617415623502083 0.3888297488314978 1.0 0.5657806715163736 13 P05067,Q08722,P04062 3 +Constitutive secretory pathway 0.4282026706736576 0.860356503632168 0.389592554817801 1.0 0.5665826233756927 3 Q15907 1 +Positive regulation of response to endoplasmic reticulum stress 0.4770628733849906 0.8601183594695657 0.3897238017651534 1.0 0.5665826233756927 10 P46379,Q9UMX0,P57088,Q07812,P51572 5 +Positive regulation of endothelial cell proliferation 0.447346840568772 0.8593523548028409 0.3901461475867394 1.0 0.5668225740604002 13 P09601,P31749,Q9H2J4 3 +Positive regulation of leukocyte mediated immunity 0.3809419053883707 0.8542686181695869 0.3929561709709608 1.0 0.5702782902826262 23 O15400,P04439,P01889,Q96FZ2,Q9NUQ9 5 +Detection of light stimulus 0.4650287943509557 0.852579656268256 0.3938924481795816 1.0 0.5712607395257526 4 Q15555 1 +Regulation of mitotic recombination 0.4265837773830838 0.8511903405811677 0.3946636277046329 1.0 0.5718772013812583 3 P18074,P49959 2 +Long chain fatty acyl coa metabolic process 0.490009977577426 0.8507744107876852 0.3948946789723013 1.0 0.5719611951189875 9 Q9UKU0 1 +Positive regulation of regulated secretory pathway 0.4643942062340375 0.8492396533182928 0.3957479526095366 1.0 0.5730652485856962 4 P11279 1 +Leukocyte degranulation 0.4748561089857166 0.8478782449454165 0.3965057814013806 1.0 0.573791703368015 10 P09601,P11279,Q99584 3 +Membrane raft organization 0.4747402458389528 0.8472359871080438 0.3968635984967164 1.0 0.5741837833767073 10 P50897 1 +Negative regulation of protein dephosphorylation 0.4524514110091111 0.8461903304401311 0.3974465753047842 1.0 0.5746498394638633 12 O75116,P62942,P62258,P49841,Q15257,O43768 6 +Regulation of biomineralization 0.4744612312792592 0.8456895055350916 0.3977259790974408 1.0 0.5748051641423111 10 O75116,P22413,O95747,O75844 4 +Cellular response to cadmium ion 0.516085156621406 0.8442581334066708 0.398525175749896 1.0 0.5755797391894805 7 P09601 1 +Long chain fatty acid transport 0.4292539799694929 0.8440680209610886 0.3986313964188128 1.0 0.5756073626681089 15 P50416,P31749,P31751,O43772,P28288,P14174 6 +Cellular metabolic compound salvage 0.4585838395062558 0.8418320389952171 0.3998819754893183 1.0 0.5770349292595863 11 Q9BV57,P00813 2 +Regulation of glucose transmembrane transport 0.4202498894746704 0.8397055756849411 0.401073487002678 1.0 0.5782492747820024 16 P31749,O75298,P31751,P22413,Q16625 5 +T cell homeostasis 0.5145685818375725 0.8368185754469367 0.4026945544876155 1.0 0.5798986273411082 7 P31749,Q9HCL2 2 +Regulation of neurotransmitter levels 0.3513160798402429 0.8358370707429298 0.4032465684432069 1.0 0.5802431027304931 33 P16615,Q13277,P50897,O95721,Q99808,P20339,P49841,Q9P253,Q7L0J3,Q4J6C6,P0DP25 11 +Mitochondrial outer membrane permeabilization 0.4863856006822457 0.8315298023403791 0.4056743995188132 1.0 0.5828023575585566 9 Q07812,Q9UII2,P45880 3 +Cellular response to osmotic stress 0.4427122238418417 0.8309924476110758 0.4059778958636628 1.0 0.5830308374104624 13 O95202,P30536,O95747,Q9BPX6 4 +Regulation of cyclic nucleotide phosphodiesterase activity 0.4220152462764902 0.8253830223386593 0.4091541705908965 1.0 0.5864133335512678 3 P0DP25 1 +Negative regulation of mitochondrion organization 0.4093987638973555 0.8248640240505002 0.4094487930727675 1.0 0.586453195608392 17 O60313,P31749,P10909,P30536,Q9H3K2 5 +Response to lead ion 0.4597008527494109 0.8245818116965474 0.4096090509926169 1.0 0.586453195608392 4 P05067 1 +Exocytosis 0.2996636111765994 0.8245560766501842 0.4096236668258652 1.0 0.586453195608392 76 Q15907,Q13277,P16615,O95721,O43633,Q99584,O43760,P09601,O15498,P49755,P20339,Q92905,P11279,Q7L0J3,Q4J6C6,Q8N5M9,O15126,P0DP25 18 +Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest 0.4218472468916611 0.8244357715992395 0.4096919963873424 1.0 0.586453195608392 3 P61254,P04637 2 +Positive regulation of cell cell adhesion 0.349150716882633 0.8210492583658119 0.411618210963347 1.0 0.5882279832338421 34 P00813,P30825,Q9HCL2,Q08722,Q9NUQ9 5 +Cellular response to amyloid beta 0.4980875930874702 0.8205355088736929 0.4119108952044517 1.0 0.5882279832338421 8 Q99538,P49841,Q9UNH7,P05067 4 +Response to amyloid beta 0.4980875930874702 0.8205355088736929 0.4119108952044517 1.0 0.5882279832338421 8 Q99538,P49841,Q9UNH7,P05067 4 +Macromolecule deacylation 0.3476149823754434 0.8191328825279919 0.4127106029042571 1.0 0.5887373731658968 38 Q9NUJ1,Q9UMR5,P50897 3 +Negative regulation of receptor signaling pathway via jak stat 0.4586266055007557 0.8189495169372584 0.4128152167934829 1.0 0.5887373731658968 4 Q8WXW3 1 +Negative regulation of receptor signaling pathway via stat 0.4586266055007557 0.8189495169372584 0.4128152167934829 1.0 0.5887373731658968 4 Q8WXW3 1 +Negative regulation of transporter activity 0.4083142111622234 0.8173867466536551 0.4137074472119841 1.0 0.5895236120408867 17 Q9UMX0,P62942,Q96PU5,P62258,P46934,O95747,P0DP25 7 +Regulation of proteasomal protein catabolic process 0.2974196521930161 0.8165668499636907 0.4141760059357431 1.0 0.5900601903921807 74 P31749,Q9UL15,P46379,Q9UMX0,P49069,P04062,Q9UL46,P24941,Q9Y297,P10909,Q96HY6,P61289,P51572,Q9UBS8 14 +Regulation of erad pathway 0.5102784804473828 0.8158091423237099 0.4146093035526457 1.0 0.5904229448781374 7 P51572,Q9UMX0 2 +Regulation of the force of heart contraction 0.4578235925785815 0.8147422575031127 0.4152198593567182 1.0 0.590970464253765 4 P10253,P05023 2 +Lysosomal transport 0.3366957789060778 0.8114266135497897 0.4171207208513603 1.0 0.592977165865055 47 O15118,O43633,Q14108,Q9NZJ7,P46934,P10909,P07602,P11279,P51809,Q96L92 10 +Regulation of lipoprotein particle clearance 0.5085802967400581 0.8075081695083364 0.4193737697040736 1.0 0.5954116528408642 7 P61978,Q92945,P41240,P30533 4 +Cellular modified amino acid catabolic process 0.5084853723315951 0.8070444329197063 0.4196408843161721 1.0 0.5956629305080716 7 Q9UHG3 1 +Cd40 signaling pathway 0.4563221794492012 0.806882774528995 0.419734023868173 1.0 0.5956672028655262 4 P35232,Q99623,P05556 3 +Regulation of leukocyte differentiation 0.3696097002448467 0.80622946408205 0.420110552724187 1.0 0.5960735601017931 26 P00813 1 +Transcytosis 0.4812740984934929 0.8044586746791301 0.4211321266514214 1.0 0.5970103442812622 9 Q15907,P20339,P30533 3 +Positive regulation of cell cycle checkpoint 0.4860781990521203 0.7963491604627735 0.4258291191690091 1.0 0.6026348283914307 5 Q5JVF3,P12270,Q8N163,Q13257 4 +Positive regulation of interleukin 1 production 0.5058622525798773 0.7942412048577805 0.4270550248910587 1.0 0.6038525159403096 7 P49755,P05067 2 +Positive regulation of production of molecular mediator of immune response 0.3759645211772555 0.7928008236552543 0.4278938765608802 1.0 0.6046505516764715 21 P14174 1 +Response to misfolded protein 0.4648011986016115 0.7923039395172664 0.4281834751767106 1.0 0.6048011514090362 10 P10909,Q9BUN8 2 +Production of molecular mediator of immune response 0.3466026977912706 0.7917192940178558 0.4285243697025795 1.0 0.6049296756403281 33 P09601,P14174 2 +Positive regulation of reactive oxygen species metabolic process 0.4288970710123442 0.7916769588555841 0.4285490605761863 1.0 0.6049296756403281 14 P30536,P00403 2 +Protein localization to plasma membrane 0.2947604915155785 0.7888382204111337 0.4302065676918398 1.0 0.606492151423927 91 Q13277,P05026,Q5VZ89,Q9H4A5,P31749,O00264,P35613,Q9H4A6,Q4J6C6,Q9BXS4,P98194,Q8N3R9,P31751,Q15363,Q9BZG1,O15400,Q13501,Q9H223,O75915,O15258 20 +Chemical synaptic transmission postsynaptic 0.427981361514823 0.785940743639307 0.431902203359666 1.0 0.6080532071505019 14 P31749,Q99808,P05067,Q9UQB8,Q14168 5 +Regulation of postsynaptic membrane potential 0.427981361514823 0.785940743639307 0.431902203359666 1.0 0.6080532071505019 14 P31749,Q99808,P05067,Q9UQB8,Q14168 5 +Exploration behavior 0.4839540163358243 0.7858456700242761 0.431957907031564 1.0 0.6080532071505019 5 Q05086,Q9HB07 2 +Cellular response to topologically incorrect protein 0.3439225719646901 0.784120724083355 0.4329692761759163 1.0 0.6090876854505387 40 Q9GZP9,P46379,P57088,O76024,Q92905,Q9BUN8,Q9Y4P3,Q96HY6,Q15363,Q13438,Q07812,P18031,P48723 13 +Regulation of mitochondrial fission 0.4770026045376098 0.7819056314155902 0.4342700352394306 1.0 0.6103989206411231 9 Q9GZY8,Q9NUQ9 2 +Regulation of inclusion body assembly 0.490284186860619 0.7809385200418838 0.4348386550646013 1.0 0.6109372175429315 8 Q9UL15 1 +Intestinal hexose absorption 0.3773305711749138 0.7778582082496893 0.4366526080074231 1.0 0.6132250502169697 2 P15311 1 +Regulation of protein secretion 0.3316545416336623 0.7767372777359006 0.4373137887041634 1.0 0.6140231207872989 48 Q9H4A5,Q5T9L3,P53985,Q96KC8,Q32P28,P49755,Q16850,O43768,Q8N5M9 9 +Presynapse organization 0.5142462928260423 0.7758291486837926 0.4378498708017702 1.0 0.6146452413187976 6 P05067 1 +Carbohydrate transmembrane transport 0.3932402086239729 0.7739250137375685 0.4389751364623027 1.0 0.6154405339158588 18 P31749,P22413,P31751,O75298 4 +Positive regulation of glycoprotein metabolic process 0.4753000563914155 0.772935440094586 0.4395605893177978 1.0 0.6157388585844269 9 Q92542,P35222,P35610,Q9H0U4,P62820 5 +Erythrocyte maturation 0.4123741859088307 0.7712485684052764 0.4405596111066863 1.0 0.6167461278974984 3 P18074,Q96KR6 2 +Organophosphate catabolic process 0.3421850606743644 0.7679035554549917 0.4425444849652868 1.0 0.619000317700652 36 P00813,Q9H773,Q8NHP8,Q9BQG2,P22413,Q10713,O75874,Q8WTV0,Q8N2K0 9 +Pyroptosis 0.3749630068067558 0.7635640858488743 0.4451270582804267 1.0 0.6219498403535456 2 Q9NZI8 1 +Regulation of intracellular transport 0.282503455633937 0.7626580545157556 0.4456673521907199 1.0 0.6221832553080837 122 Q92544,Q15907,Q9GZP9,Q00765,Q9BWF3,O14737,O95429,P46934,P06493,P55786,P27105,P51572,Q7Z4L5,Q9BZL1,Q9GZY8,Q9Y282,P11279,P49257,Q13438,P18031,P50402,P60604,Q08J23,P62258,P31751,Q9NR31,O43464,Q9UII2,Q9P2W9,Q13263,Q9Y3B8,Q9C0E2,P49841,P27361 34 +Glandular epithelial cell development 0.4991529667767619 0.7616018639000696 0.4462976620545178 1.0 0.6229316258750387 7 P31749,Q15382,Q86UL3 3 +Autophagosome organization 0.360056988367821 0.7611315144296409 0.4465785188734492 1.0 0.6230604668006389 28 P16615,Q9Y4P1,Q9UMX0,P04062,P53365,Q8TBX8,P20339,Q86Y82,Q5MNZ6,Q9H0U4,P51149,Q7Z3C6 12 +Protein targeting to vacuole 0.3996107328160886 0.7575590030483376 0.4487150309484251 1.0 0.6252493441994817 17 P10909,Q14108,P46934 3 +Cellular protein catabolic process 0.2751883415276158 0.7562368626861812 0.449507195046372 1.0 0.6260891574418278 253 Q9UBV2,P50897,Q05086,P28074,P49069,Q96PU5,Q16740,P07858,Q9GZP9,P30260,O00231,Q9UMX0,P46934,Q96HY6,Q9H2J4,P61289,Q9BRG1,P51572,Q9BW61,P31749,Q9UL15,O43633,P53634,Q96K76,Q9BUN8,Q9Y297,Q9UG56,Q8N511,P04062,P33908,Q8TCT9,Q9UL46,P24941,P10909,Q9UJX3,Q9UHG3,Q9Y5X3,O75844,O14773,O43464,P28072,Q96A33,P46379,Q13501,Q9UBS8 45 +Lymphocyte mediated immunity 0.3414846996759994 0.7544775355308244 0.4505625295489324 1.0 0.6271971491178584 35 O15400,P53634,P04439,P01889,P10909,P11279,Q96FZ2,Q9NUQ9 8 +Positive regulation of endothelial cell migration 0.3682917881932933 0.7535134431904499 0.451141436124906 1.0 0.6276993288605675 23 P31749,P09601,Q99538,P78536,P06576,Q8WTV0 6 +Developmental pigmentation 0.4843955878650612 0.7512045501490865 0.4525295622522969 1.0 0.6292379290817232 8 P22413,Q86YV9 2 +Positive regulation of gene expression 0.277335245795637 0.7506618208345078 0.4528562056383436 1.0 0.6295596682927668 227 P98179,Q99584,O14737,Q9Y2R0,Q96HY6,O00571,Q9H2J4,O15031,P35637,P31749,P62995,P04439,P09601,Q9H1D9,Q13151,P05067,Q99729,Q9NUQ9,O60506,P38159,P14174,Q92804,P08670,Q15363,P10909,Q16625,Q8WXW3,Q96FZ2,O75844,Q96QD8,P98175,Q14011,P49755,P67809,Q96I24,Q9NUD5,Q14103,O95747,Q96AE4,Q567V2 40 +Regulation of muscle contraction 0.3662286102633422 0.749148525294087 0.4537676902851195 1.0 0.6305255103470006 24 P00813,P16615,P05023,P09493,P0DP25 5 +Response to cold 0.4291917506201615 0.7487166973047364 0.4540279775671623 1.0 0.6305255103470006 13 P00403 1 +Regulation of neurotransmitter transport 0.4059607910233954 0.7445567766351597 0.4565397059729676 1.0 0.6332153025761476 16 P16615,P20339,P49841,Q4J6C6,P0DP25 5 +Regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.4558106856152972 0.7429379928832146 0.4575192222826276 1.0 0.6344407343822673 10 P61978,P14174 2 +Regulation of proteasomal ubiquitin dependent protein catabolic process 0.315878713124919 0.7406719438876814 0.4588923745611577 1.0 0.635811258590082 54 P31749,Q9UL15,P46379,Q9UMX0,P49069,P04062,P24941,P10909,Q96HY6,P51572,Q9UBS8 11 +Heart process 0.3443907192611896 0.7403284021865788 0.4591007511356062 1.0 0.6359269511999058 32 P00813,P05023,Q96PU5,P09493,P10253,O75844,P0DP25 7 +Cholesterol efflux 0.4690708936461255 0.7402170269276315 0.4591683176162733 1.0 0.6359269511999058 9 O15118,Q8WTV0 2 +Development of primary female sexual characteristics 0.4342404361150948 0.7384140754615084 0.460262863839409 1.0 0.6373092954357122 12 O95470,Q05086,O75874 3 +Lymphocyte migration 0.427297357872306 0.7372541759826204 0.4609677932334428 1.0 0.6381516852701767 13 P31749,P04062,P05067,O95747,P78536 5 +Double strand break repair via break induced replication 0.4815095595286149 0.7366831870701742 0.4613150335218379 1.0 0.6382808846951814 8 Q14566,P33991,Q9BRT9 3 +Interferon gamma production 0.4939179190566656 0.7362528515221465 0.4615768336441648 1.0 0.6382808846951814 7 Q08722,Q9NUQ9 2 +Regulation of membrane permeability 0.387886760292339 0.7359950287677618 0.4617337231493243 1.0 0.6382808846951814 18 P12235,P45880,Q07812,P52789,Q9UII2 5 +Cellular response to lipid 0.2810877824236936 0.7354778114950729 0.4620485483748253 1.0 0.6382808846951814 114 Q05086,P05023,O15173,P46934,Q96HY6,O15118,P31749,O43251,Q86U42,Q86UE4,P14174,O75116,P50416,P08670,P10909,O95831,O43464,Q8WTV0,P49841,P16220,Q14103,P30536,Q9P253,Q9Y263,O95747,Q9UBS8,P27361 27 +Negative regulation of p38mapk cascade 0.370227878070445 0.7350965685348451 0.4622806840207341 1.0 0.6382808846951814 2 P15311 1 +Potassium ion export across plasma membrane 0.3702278780704423 0.7350965685348283 0.4622806840207443 1.0 0.6382808846951814 2 Q4KMQ2 1 +Regulation of potassium ion export across plasma membrane 0.3702278780704423 0.7350965685348283 0.4622806840207443 1.0 0.6382808846951814 2 Q4KMQ2 1 +Macrophage activation 0.4679385637432887 0.734287652131147 0.462773441914218 1.0 0.6384168689801185 9 P10909,P14174,P05067 3 +Receptor metabolic process 0.3386774797907683 0.7342415798834383 0.4628015160060141 1.0 0.6384168689801185 36 Q15907,P49069,Q99538,P20339,P42892,P46934,P30533,P18031,Q96J02,Q8NBU5 10 +Regulation of ubiquitin dependent protein catabolic process 0.3061099639192484 0.7323237056836033 0.4639710135938371 1.0 0.6398965836480945 62 P31749,Q9UL15,Q05086,Q9UMX0,P46379,P49069,P04062,P24941,P10909,Q96HY6,Q9H2J4,P51572,Q9UBS8 13 +Regulation of granulocyte chemotaxis 0.4672487099111715 0.7306781601345698 0.4649757585732321 1.0 0.6411485058231777 9 Q8NHP6,Q8NE86,Q00013,P27361,P28482 5 +Cellular anion homeostasis 0.4048625439849485 0.7294308181796988 0.4657381720040083 1.0 0.6419207637513249 3 P22413 1 +Regulation of protein localization to cell surface 0.4186380533789841 0.7276330725857642 0.466838229688157 1.0 0.6428186635464874 14 Q92544,Q15907,Q13277,P31749 4 +Forebrain cell migration 0.4256969191262897 0.7275847075558791 0.4668678446093417 1.0 0.6428186635464874 13 Q00535,P35222,Q96N66,P00533,Q9NQC3,P07942,O94901 7 +Response to growth hormone 0.440974368782439 0.727126723160312 0.467148329704715 1.0 0.6430708833614791 4 P31749 1 +Biomineralization 0.3948502915451689 0.724992072443931 0.4684568938547619 1.0 0.6447379449158938 17 O75116,Q9Y4P1,Q6P4Q7,Q4KMQ2,P22413,O95747,O75844 7 +Regulation of reactive oxygen species metabolic process 0.3426699588441222 0.7245526896416226 0.4687264919089278 1.0 0.6449746793724972 32 Q9BSK2,P00374,P30536,P42785,P00403 5 +Amide transport 0.3316023072707067 0.7239474532735625 0.4690979955368943 1.0 0.645351509680128 45 Q15907,P50416,Q9H2D1,P53985,Q8N183,Q9NZJ7,Q9BRT2,Q9Y289,P07602,O43768,P08183,Q8N5M9 12 +Ribose phosphate biosynthetic process 0.2955066449543637 0.7224749328118513 0.4700025316234419 1.0 0.6463268271950329 80 P00813,P50897,Q8TB61,P00846,Q9UMR5,O75964,Q9UKU0,P00403 8 +Execution phase of apoptosis 0.4025226106425554 0.7218075252448815 0.4704128221726722 1.0 0.6466971256484019 16 P31749,Q07812,Q8IXJ6,O95831,Q12981,O43464 6 +Isocitrate metabolic process 0.5026456091160418 0.7217185888439885 0.4704675109876708 1.0 0.6466971256484019 6 P48735 1 +Tumor necrosis factor superfamily cytokine production 0.3855264213689594 0.7193219822608813 0.4719425546699329 1.0 0.6484549571338019 18 P10909,P30536,P14174,P05067 4 +Hepaticobiliary system development 0.3376434627753599 0.717985734253582 0.4727660829566917 1.0 0.6491816003035062 35 P09601,P00813 2 +Regulation of lymphocyte activation 0.3074625520619463 0.7170378169350419 0.4733507627507867 1.0 0.6498494372704505 60 P00813,P31749,P04439,P30825,Q9HCL2,Q8WXW3,Q08722,Q96FZ2,Q9NUQ9,O96005,P14174 11 +Synaptic vesicle membrane organization 0.501599974902185 0.7168678639335906 0.4734556325838335 1.0 0.6498584165621092 6 O95721,O43760 2 +Vacuolar transport 0.3116332187841653 0.7134539698330153 0.4755648868281918 1.0 0.6522117321119568 56 O15118,Q9BRG1,O43633,Q14108,Q9NZJ7,P46934,P10909,P07602,P11279,P51809,Q96L92,P13473 12 +Torc2 signaling 0.4382588095943037 0.713141035282364 0.4757584891266742 1.0 0.652341878555641 4 Q9Y4R8,Q96A49,Q9NWS0 3 +Glial cell migration 0.4232485571779597 0.712819057577741 0.4759577312279837 1.0 0.652344389399781 13 Q96N66,P07686,P30536,Q96G23,Q9NQC3,O94901 6 +Positive regulation of protein localization 0.275771600854387 0.7118098938282418 0.4765825052167665 1.0 0.6527337296408461 146 Q92544,Q13277,Q96D46,O14737,Q9BQT9,Q96C92,Q96HY6,P06493,P55786,P27105,P51572,Q9BV73,Q9H4A5,P33176,P31749,Q5T9L3,O00264,Q9BZL1,Q9GZY8,Q9H4A6,Q9Y282,P50402,O75116,P62258,Q66GS9,Q14696,P31751,P98194,Q9NQC3,Q9NR31,O43464,P49755,Q13263,Q9Y3B8,Q9C0E2,Q8NE86,Q13501,P49841,O15258 39 +Membrane repolarization 0.4636186698570791 0.7117221387194222 0.4766368556887159 1.0 0.6527337296408461 9 P05023,Q96PU5,P05026,P62258,P54709,O75844 6 +Negative regulation of immune system process 0.319847830509306 0.7110784748070528 0.4770356078823159 1.0 0.6530091823724578 51 P00813,P31749,P09601,P01889,Q9HCL2,Q08722,P14174 7 +Negative regulation of small gtpase mediated signal transduction 0.4499202037915229 0.7107943224513988 0.4772116994132767 1.0 0.653114955771867 10 P16949 1 +Negative regulation of cell death 0.2751693571952832 0.7076356705541612 0.4791715354340722 1.0 0.6551993745956232 228 P07196,P00813,P50897,P61978,P21796,Q01105,Q92905,Q96HY6,O00571,P61289,Q86XL3,O95881,Q9H3K2,O15118,Q9UL15,P31749,P45880,P78318,O43633,P16435,P09601,Q15041,Q9H4A6,Q96K76,Q86UE4,P14174,O60313,P04062,Q9UEE9,Q9UMX5,P31751,Q9HCL2,P10909,O43464,Q15392,P46379,O75489,Q9Y3B8,Q07820,O95747,Q9NVI7,Q12981,Q8NDZ4 43 +Bone development 0.3506796608072136 0.7073909161655362 0.4793235804034514 1.0 0.6551993745956232 29 Q32P28,Q9NX62,P16435,Q15125,O75844,Q7RTS9 6 +Multicellular organism reproduction 0.2790720763475356 0.7062092110381655 0.4800580430589569 1.0 0.6560594719968251 124 P00813,P07858,Q8N2A8,O00571,Q9Y2W6,P51572,Q9BPZ3,P31749,O75718,Q9H2V7,P35613,P05067,Q9BQE5,P41208,Q9BTX1,Q08J23,Q15067,Q15363,Q07812,Q01085,O94901,O95470,P46379,P09622,Q9H6S0 25 +Response to ketone 0.3349059530643175 0.7054251972114147 0.4805456678932684 1.0 0.656454385925302 41 P07196,P31749,Q05086,P16435,P04062,Q9H4A6,Q14103,P30536,O95831,P16278,P0DP25 11 +Regulation of phosphatidylinositol 3 kinase signaling 0.4219272813698013 0.7048646919114553 0.4808944448559835 1.0 0.6565237318845683 13 Q8NDZ4,Q10713,P46934 3 +Cerebral cortex development 0.3436162344193328 0.7033590999326254 0.4818319884527691 1.0 0.6572606009668424 31 P07196,P62995,Q00535,P35222,Q15058,Q96N66,P62258,P00533,Q8N3R9,P49841,Q96P11,Q07812,Q9NQC3,Q96QD8,P07942,O94901 16 +Purine containing compound biosynthetic process 0.2899518847798878 0.7013232336328711 0.4831013174738561 1.0 0.6584484650824325 75 P00813,P50897,Q8TB61,P00846,Q9UMR5,O75964,Q9UKU0,P00403 8 +Positive regulation of glucose import 0.4977383515363145 0.6989953510826173 0.4845549361592605 1.0 0.6601574052930432 6 P31749,P31751 2 +Regulation of genetic imprinting 0.3640130216040323 0.6980012927858137 0.4851763855812123 1.0 0.6608678343582507 2 Q13263 1 +Positive regulation of receptor internalization 0.399052693901723 0.6973389887797401 0.4855906736290052 1.0 0.6612958504047177 3 Q06787,Q8NBU5 2 +Response to interleukin 1 0.4202924565351526 0.6950368681310444 0.4870321969799187 1.0 0.6624399649805068 13 P05067,Q86Y07,Q08722,P38159,Q9H6S0 5 +Quinone metabolic process 0.4265394268480895 0.6933049255477193 0.4881182126218653 1.0 0.6636439554038074 12 Q8N0U8,Q8NI60 2 +Negative regulation of intracellular signal transduction 0.2775878990932241 0.6900265161535885 0.4901775124649428 1.0 0.6659276160619462 106 O00571,O43657,O95881,P31749,Q9UL15,P16949,P45880,P78318,Q96K76,Q9NUQ9,P14174,O60313,P04062,P10909,O43464,O75489,Q07820,P57105,Q10713 19 +Neutrophil mediated immunity 0.4642388917258943 0.6892892824893979 0.4906412410875802 1.0 0.6662518928185366 5 P51809,Q8N5M9 2 +Regulation of membrane protein ectodomain proteolysis 0.4335208765176125 0.6888435709469168 0.4909217132142411 1.0 0.6664789906310712 4 O43847,Q9Y5X1,Q13443 3 +Regeneration 0.3386375714922398 0.6876486023506256 0.49167409392708 1.0 0.6669692296313777 32 P07196,P50416,P09601,P00374,P30536,Q96G23,P10586 7 +Regulation of mitochondrial membrane permeability 0.4121118966714581 0.6871823854527398 0.4919678029572285 1.0 0.6672307017739223 14 P12235,P45880,Q07812,P52789,Q9UII2 5 +Dna damage response signal transduction by p53 class mediator 0.4047110062112331 0.6861465655447057 0.4926206893563827 1.0 0.66784207917053 15 P14174 1 +Regulation of cell population proliferation 0.2718888990500229 0.6850820319847901 0.4932921578861511 1.0 0.6684781364505993 253 P00813,Q9GZP9,O14737,P09493,Q9BSK2,Q96HY6,Q9H2J4,P43490,P43307,P31749,O43251,Q9NR77,P09601,P05067,P50402,P14174,Q14534,Q32P28,Q9UEE9,P31751,Q9HCL2,P24941,P10909,Q08722,Q96G23,Q9NQC3,O75844,Q71SY5,Q15392,P98175,Q9Y3B8,P30825,Q9NPI1,P57105,P30536,P52756,O95684 37 +Smoothened signaling pathway 0.3595379230934719 0.6842504251456981 0.4938170456674018 1.0 0.6690522457597087 23 Q9Y297,P22413,O43805,Q9BZG1 4 +Response to leucine 0.3963883955002969 0.682703445269863 0.4947942522501714 1.0 0.6696800554535784 3 Q9P2J5,P42345 2 +Cellular response to leucine 0.3963883955002969 0.682703445269863 0.4947942522501714 1.0 0.6696800554535784 3 Q9P2J5,P42345 2 +Phospholipid metabolic process 0.2918709972822714 0.6825545004472199 0.4948883932267025 1.0 0.6696800554535784 79 Q9UG56,Q86YN1,Q9NX62,Q8NHP8,Q9BVG9,Q96N66,Q96JX3,Q9HBU6,Q9HCL2,Q10713,Q9NPH0,O43292,O15269,O75874,Q86UL3,Q8WTV0,Q8N2K0 17 +Dendritic cell chemotaxis 0.4320402724311376 0.6812791203874224 0.4956948923755677 1.0 0.670359636527548 4 Q4KMQ2,Q07021,P09429 3 +Myeloid leukocyte mediated immunity 0.396227695610578 0.6803385222155285 0.4962901381151323 1.0 0.6706906266608406 16 P09601,P51809,Q99584,Q8N5M9 4 +Reactive oxygen species metabolic process 0.3287692163733414 0.6802509643386915 0.4963455674078032 1.0 0.6706906266608406 44 Q15067,Q9BSK2,P00374,P30536,Q13423,P42785,P00403 7 +Anterograde neuronal dense core vesicle transport 0.3604616750517979 0.676954722619715 0.4984346822169208 1.0 0.6727765326584955 2 P33176 1 +Dense core granule transport 0.3604616750517979 0.676954722619715 0.4984346822169208 1.0 0.6727765326584955 2 P33176 1 +Generation of precursor metabolites and energy 0.2755704402835697 0.6763383179045963 0.4988258697757002 1.0 0.6730788430681099 190 P56385,Q99623,P14406,Q9UDW1,Q9BSK2,P20674,O43674,P35610,P00846,O75874,O43676,P06576,P06493,P52789,O75438,O75964,Q9H3K2,O75306,P09669,P00403,P43304,P31749,Q8NC60,P16435,P22830,P05067,O43175,P21912,P48735,P54619,O95168,O75208,O95298,Q9Y6M9,P13073,Q15067,Q9BRR6,P04062,P14927,P24539,P31751,O14949,Q9UII2,Q9BRT2,P46976,P12235,P36542,Q9NZ45,P09622,O15460,O75489,P03886,P22695,P49841,Q9H936,P15954,P10606,P10253,Q9NQ88,P22413,Q13423,P56134,O14548 63 +Cleavage furrow formation 0.3949082297217247 0.6745960207415095 0.4999324618412628 1.0 0.6738840791982268 3 Q9Y5X1,Q96GD4 2 +Nucleoside phosphate biosynthetic process 0.2795266426655481 0.6742031571759249 0.5001821626987346 1.0 0.6739457519420871 94 P00813,P50897,Q8TB61,Q9BQG2,P00846,P43490,Q9UMR5,O75964,Q9UKU0,P00403 10 +Negative regulation of smoothened signaling pathway 0.4922228598192464 0.6735885347677062 0.5005729443401084 1.0 0.6743348122999951 6 Q9Y297 1 +Placenta blood vessel development 0.468687992719986 0.6726378429455643 0.5011777201926089 1.0 0.6748743995014165 8 Q15363 1 +Negative regulation of nervous system development 0.3606348034788581 0.6678964835753075 0.5041996721858752 1.0 0.6778388188520035 20 P30536,Q96G23 2 +Positive regulation of natural killer cell mediated cytotoxicity 0.4292228220795799 0.6669241248812878 0.5048206001848734 1.0 0.6782596760768099 4 P11279 1 +Positive regulation of natural killer cell mediated immunity 0.4292228220795799 0.6669241248812878 0.5048206001848734 1.0 0.6782596760768099 4 P11279 1 +Cd4 positive alpha beta t cell differentiation 0.3931320307874549 0.6648899918391139 0.5061208574626033 1.0 0.6791045944256499 3 P09429,P42345 2 +T helper 1 cell differentiation 0.3931320307874549 0.6648899918391139 0.5061208574626033 1.0 0.6791045944256499 3 P09429,P42345 2 +T cell differentiation involved in immune response 0.3931320307874549 0.6648899918391139 0.5061208574626033 1.0 0.6791045944256499 3 P09429,P42345 2 +T helper 1 type immune response 0.3931320307874549 0.6648899918391139 0.5061208574626033 1.0 0.6791045944256499 3 P09429,P42345 2 +Prolactin secretion 0.3931320307874474 0.6648899918390723 0.5061208574626299 1.0 0.6791045944256499 3 Q7Z7E8,P80404 2 +Female sex differentiation 0.4149207563897153 0.6628620890424051 0.5074188839273674 1.0 0.6803385242463383 13 O95470,Q05086,O75874 3 +Cdc42 protein signal transduction 0.3925399644760212 0.6616603215159934 0.5081889392441963 1.0 0.680518346565145 3 A0MZ66,P60953 2 +Dendrite arborization 0.392539964476021 0.661660321515992 0.5081889392441972 1.0 0.680518346565145 3 Q9NZI8,Q13641 2 +Salivary gland development 0.3925399644760177 0.661660321515974 0.5081889392442087 1.0 0.680518346565145 3 P00533,P60953 2 +Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.3924556481678385 0.6612006173894116 0.5084836653849965 1.0 0.680518346565145 3 Q07820 1 +Regulation of protein localization to membrane 0.3111547767811652 0.6607351271629676 0.5087821924142073 1.0 0.680518346565145 53 P31749,Q13277,O15400,O00264,O14737,Q13501,Q9GZY8,P98194,P31751,P27105,Q9BXS4,O15258 12 +Microtubule anchoring at centrosome 0.4581137047424642 0.6596927617729624 0.5094510125834126 1.0 0.6810197698551324 5 P49841 1 +Chondrocyte differentiation 0.4533358017747978 0.6583980896997088 0.5102823625855333 1.0 0.6819931515324145 9 Q92896,Q9NX62,P16435 3 +Ventricular cardiac muscle tissue development 0.4532931233477326 0.6581780203529554 0.5104237466110995 1.0 0.6820441854736669 9 O75844 1 +Hindbrain development 0.330902815663213 0.6558982145163257 0.5118896171058411 1.0 0.6831741679023634 40 Q5T9L3,O43251,O95456,P04062,O14949,P54802 6 +Bone mineralization 0.4200617989873132 0.6556353844509331 0.5120587527941549 1.0 0.6832619215054654 12 P22413,O75844 2 +Defense response 0.2732117630660271 0.6549445964447571 0.5125034257734924 1.0 0.6833369805269243 221 P00813,P49069,Q16543,Q9BPX6,P01889,O00571,O43657,P31749,P53634,P04439,P09601,Q9H1D9,Q13151,Q8IV08,P05067,P11279,Q9BQE5,P51809,Q8N5M9,O60506,Q9NZ08,P14174,P04062,Q99735,P10321,Q9HCL2,P08670,P10909,Q08722,O75844,Q01085,Q8N2K0,O00584,Q9NUD5,Q8IXJ6,P23246,P78536,Q9H0P0,P42785,Q9NVI7 40 +Centriole assembly 0.4526520507809499 0.6548736823597266 0.5125490858689228 1.0 0.6833369805269243 9 P41208,Q96PK6,O43633,P24941 4 +Schwann cell differentiation 0.4257208501512677 0.6537940344530624 0.513244510386027 1.0 0.6835768672736301 11 P31749,Q8IXJ6,Q8N3R9,P31751 4 +Roof of mouth development 0.4648235228437944 0.6535022695961803 0.5134325267281434 1.0 0.6835768672736301 8 O95470 1 +Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.390305719130568 0.649498941313264 0.5160159305221761 1.0 0.6867396868346882 3 Q99729 1 +Fluid transport 0.3554306007694658 0.6473450714532687 0.5174086372575 1.0 0.6876093566721425 2 O43865 1 +Mitochondrial genome maintenance 0.4511616346155673 0.6472012058675187 0.5175017309861154 1.0 0.6876093566721425 9 O60313,Q9BSK2 2 +Golgi disassembly 0.4549615337255882 0.6445483441186113 0.5192199191225071 1.0 0.6891995271099918 5 Q13190 1 +Regulation of response to oxidative stress 0.3564011851164931 0.6425257986929855 0.5205318439545048 1.0 0.6902477842486602 21 P31749,Q9UL15,Q9UMX0,Q07820,P00374,P23246,O43464 7 +Regulation of neuron projection regeneration 0.4243694349290465 0.6423234896721931 0.5206631656848328 1.0 0.6902834226702227 4 Q96G23 1 +Memory 0.4236372330601206 0.6420742262302396 0.5208249896801966 1.0 0.6903111481545446 11 Q9BPZ3,Q99538,P16220,O00264 4 +Mitotic dna replication 0.4236185921435612 0.6419695122366975 0.5208929786422627 1.0 0.6903111481545446 11 O75844 1 +Cellular carbohydrate metabolic process 0.2999258409662997 0.6401638545774643 0.5220660790916634 1.0 0.6914498430294195 61 Q9NUJ1,P31749,Q9UNI6,Q14108,Q9NX62,Q92520,P31751,P10253,O43505,Q7LGA3,P22413,Q10713,O75874,P48735,O75844,P16278 16 +Regulation of transmembrane transport 0.2927908251252399 0.6390502923350997 0.5227902152188586 1.0 0.6922701928233693 85 P31749,Q9UMX0,O75298,Q15041,P21796,P31751,P05067,P46934,P22413,Q16625,O75915,P0CG08,O75844,P27105,O95747,P08183,P0DP25 17 +Positive regulation of glucose transmembrane transport 0.4734347515369778 0.6382805716199162 0.52329105668053 1.0 0.6926128202312939 7 P31749,P31751 2 +Synaptic transmission glutamatergic 0.4727435482369174 0.6350133180445029 0.5254197290048901 1.0 0.6944997977986637 7 P51790,Q8NBU5,Q9BQT9 3 +Inclusion body assembly 0.4486566761090433 0.6343373934298271 0.5258606579699319 1.0 0.6949436289788602 9 Q9UL15 1 +Positive regulation of peptidyl tyrosine phosphorylation 0.3560916501442026 0.6337736483414291 0.5262285529863724 1.0 0.6952380395228052 20 Q8WXW3,P14174,P78536,Q9H223 4 +Muscle cell apoptotic process 0.415751738561403 0.6307281615276367 0.5282182822350427 1.0 0.6971170607599307 12 P09601 1 +Dna damage response signal transduction resulting in transcription 0.4219721646431612 0.6302351440791073 0.5285407488624467 1.0 0.6971170607599307 4 P61254,P04637,Q9UNS2 3 +Chaperone mediated protein complex assembly 0.4092693929788488 0.6292250265945771 0.5292017466917576 1.0 0.6972676124174294 13 O95456,O15212 2 +Regulation of cardiac muscle contraction by calcium ion signaling 0.4708108773465341 0.6258928767176855 0.5313852070799943 1.0 0.6991687902830345 7 P16615,P0DP25 2 +Positive regulation by host of viral genome replication 0.4812601994551704 0.6235556564893139 0.532919440093286 1.0 0.7006295165260646 6 P27105 1 +Negative regulation of proteasomal ubiquitin dependent protein catabolic process 0.3537292029924009 0.6222194091029251 0.5337976052389628 1.0 0.7014845535669944 21 Q9UL15,P49069 2 +Positive regulation of hydrolase activity 0.2723805024101229 0.6213301300136785 0.5343824332568667 1.0 0.7014845535669944 101 O14737,Q96HY6,O00571,P61289,P51572,P31749,P05067,P07602,P0DP25,Q9BXK5,Q96A26,P31751,Q9UL46,O95831,O43464,Q9NR28,Q15555,Q92542,Q9NZJ7,O75915 20 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.4807672204913497 0.6213215577366162 0.5343880723267866 1.0 0.7014845535669944 6 O60313,O95881,P18031 3 +Fatty acyl coa metabolic process 0.3938398097780244 0.6173284150911197 0.5370181281453192 1.0 0.7040417707156187 15 Q9UMR5,P50897 2 +Receptor clustering 0.4001921914973317 0.6140316017920493 0.5391944446364705 1.0 0.7064901040052406 14 Q14168,O43805,P57105,O15258 4 +Defense response to symbiont 0.2989514463594146 0.6138043688838772 0.5393446099110895 1.0 0.7065467843215838 60 Q9NUD5,Q9H1D9,Q9HCL2,Q9H0P0,O75844,O43657 6 +Regulation of tor signaling 0.3533355312674384 0.6131626593033134 0.5397687922724186 1.0 0.7066119400073083 20 Q9NWS0,O75340,Q9P2J5,P04062,Q15382,Q9H4A6,Q6IAA8,O75844,Q9UHA4 9 +Adaptive immune response 0.31794694981264 0.613082163730265 0.5398220131785292 1.0 0.7066119400073083 47 P00813,O15400,P53634,Q6P179,P01889,P10321,P10909,Q96FZ2,Q9NUQ9,Q9NZ08 10 +Regulation of low density lipoprotein particle clearance 0.4785088290557242 0.6111054745909087 0.5411297557424368 1.0 0.7072307593265423 6 P61978,Q92945,P41240 3 +Fatty acyl coa biosynthetic process 0.4123054992590932 0.6109119735964222 0.5412578575690197 1.0 0.7072307593265423 12 Q9UMR5,P50897 2 +Kidney morphogenesis 0.4437297954452368 0.6091569133286192 0.5424204364986438 1.0 0.7083297104958579 9 O75844 1 +Reproductive system development 0.2805815884001038 0.608431145257701 0.5429015600259839 1.0 0.708817939591412 72 P00813,P31749,O95470,Q9NZJ7,P07858,P35613,P07602,Q15363,O95747,O75874,Q15392 11 +Positive regulation of cyclase activity 0.3483279076649974 0.6059967432578651 0.5445169158316427 1.0 0.7105058828689688 2 P27361 1 +Macromolecule catabolic process 0.2451504946191578 0.6051024985872765 0.5451108941829166 1.0 0.7108598854883378 445 P50897,Q05086,P49069,Q96PU5,Q16740,P30260,P61289,Q9BW61,Q969T7,P53634,Q99538,Q13151,Q92945,P54802,Q8N511,P04062,P33908,Q8TCT9,Q9UHG3,O95831,O75844,O75503,O14773,P98175,P10619,P07858,P15586,Q16850,P35637,Q9NUJ1,Q9UL15,Q9BQG2,Q96K76,Q9BUN8,Q92804,P08670,Q9UJX3,Q9UIQ6,O43464,P28072,Q96A33,Q8N2K0,Q14011,O00584,P67809,P04066,O60502,Q05639,Q9UBS8,Q9UBV2,Q9GZP9,P28074,O00231,Q96HY6,Q9Y297,Q99729,O60506,Q9UG56,P24941,P10909,Q9Y5X3,P10253,Q9BRG1,Q9UMX0,Q13190,P46934,Q15024,Q9H2J4,P16278,P51572,P31749,O43633,Q08J23,Q9UL46,P08236,P46379,Q13501,Q14103 78 +B cell activation 0.3265167747983021 0.6046907921248866 0.5453844674006594 1.0 0.7109360838364809 39 P00813,P14174 2 +Positive regulation of cytoplasmic translation 0.4168205155317589 0.603952207424832 0.5458754173482152 1.0 0.7114357391548717 11 P67809,P11940,Q14103,O60506 4 +Regulation of monocyte chemotaxis 0.4768379584780796 0.6035671358931035 0.5461314678983871 1.0 0.7116291150119164 6 Q4KMQ2,Q99538,O94813,Q8NHP6 4 +Regulation of membrane depolarization 0.465973768089581 0.6031674069126515 0.5463973277721514 1.0 0.7118351940165877 7 P30536 1 +Er associated misfolded protein catabolic process 0.4658953846546795 0.6028003814546326 0.5466414929779209 1.0 0.7118726358800155 7 Q9BUN8 1 +Anoikis 0.4543644713942001 0.602165289991027 0.5470641178163285 1.0 0.712142358607074 8 Q07820,P31749 2 +Positive regulation of defense response 0.322225348112198 0.6011444070447944 0.5477438082885777 1.0 0.7125589795045276 43 P53634,Q99735,Q9H1D9,Q9NUD5,P05067,P11279,Q08722,P23246,P51809,Q9BY67,Q15233,Q96PK6,P27361 13 +Regulation of translation in response to endoplasmic reticulum stress 0.4762762600586375 0.6010368694667443 0.5478154296962483 1.0 0.7125589795045276 6 Q15363 1 +Mitochondrial protein processing 0.4760618237808228 0.6000714287434894 0.5484586328908847 1.0 0.7128491782666707 6 Q9Y4W6,Q10713 2 +Mesoderm development 0.3978840969062423 0.5999934680161485 0.5485105887441277 1.0 0.7128491782666707 14 Q5T9L3,Q14696,O95747 3 +Negative regulation of biomineralization 0.4159220238472581 0.5999250213626973 0.5485562060773908 1.0 0.7128491782666707 4 P22413 1 +Regulation of system process 0.2941123607283528 0.5998925670912735 0.5485778363843679 1.0 0.7128491782666707 63 P00813,P16615,P05023,P04062,P09493,P42892,P05067,P10253,Q9Y5X3,O75844,Q9UQB8,P0DP25 12 +Digestive system development 0.404219937073545 0.5993764049965142 0.548921907626482 1.0 0.7131560620215096 13 P00813 1 +Purine nucleoside metabolic process 0.4415008137063809 0.5978203646538067 0.5499598008605191 1.0 0.7139431003510451 9 P00813 1 +Response to topologically incorrect protein 0.2974329800017739 0.5954592364024358 0.5515365394808713 1.0 0.7154278683864728 60 Q15629,Q8TCJ2,Q9GZP9,P46379,P57088,O76024,P05198,Q92905,Q9BUN8,P10909,Q96HY6,Q9Y4P3,Q13438,Q15363,P18031,Q07812,P48723 17 +Snrna transport 0.4142730233935299 0.5917155817647403 0.5540410606674837 1.0 0.7176905860351626 4 P62826,Q9H814,Q53F19 3 +Positive regulation of protein glycosylation 0.3792184724689223 0.5898131297762451 0.5553159391440674 1.0 0.7184623162595718 3 Q99653,Q08379 2 +Regulation of sodium proton antiporter activity 0.3792184724689205 0.5898131297762362 0.5553159391440734 1.0 0.7184623162595718 3 Q99653,O43707 2 +Negative regulation of protein import into nucleus 0.3792184724689165 0.5898131297762144 0.555315939144088 1.0 0.7184623162595718 3 Q9ULC3,Q99653 2 +Positive regulation of granulocyte chemotaxis 0.4428317535544887 0.5868840844679025 0.5572815595200775 1.0 0.7203351900778784 5 Q07021,Q8NE86,O00429,Q8NHP6 4 +Positive regulation of neutrophil migration 0.4428317535544887 0.5868840844679025 0.5572815595200775 1.0 0.7203351900778784 5 Q07021,Q8NE86,O00429,Q8NHP6 4 +Nucleobase containing compound transport 0.2717751275866975 0.5853394248335958 0.5583195106184942 1.0 0.7213946521363886 110 Q8TD16,Q8TB61,Q9BSK2,Q86V81,Q16629,Q07666,P84103,P22626,Q9H2D1,P12236,Q6NUK1,Q53F19,L0R6Q1,Q86U42,O14980,P41208,Q92945,Q9BTX1,O15504,Q9Y6M1,Q08J23,Q08722,Q8NFH4,P51991,P12235,Q99808,P67809,O43808,Q8N1F7,Q15388,Q07955 31 +Positive regulation of exosomal secretion 0.4508442169473642 0.585049704264017 0.5585142961687557 1.0 0.7214950227030026 8 Q99816,O43633,P51149,O14964 4 +Positive regulation of protein dephosphorylation 0.3949291151601258 0.5820881208473249 0.5605073262446547 1.0 0.7235142420216646 14 Q86XL3,P04062 2 +Development of secondary sexual characteristics 0.4120677272595878 0.580773044830908 0.561393424275189 1.0 0.7238071792872449 4 Q07812 1 +Female meiosis i 0.3438887244747057 0.5804511615255458 0.5616104123747854 1.0 0.7238071792872449 2 O95067 1 +Male meiosis i 0.3438887244747043 0.5804511615255379 0.5616104123747907 1.0 0.7238071792872449 2 P54652 1 +Glandular epithelial cell differentiation 0.4492276560866154 0.5772196797298533 0.5637910644044555 1.0 0.7259098275178348 8 P31749,Q15382,Q86UL3 3 +Pattern recognition receptor signaling pathway 0.3262285177951656 0.574840978333426 0.5653988498409865 1.0 0.7269885211282257 32 O43657,Q9NUD5,Q9NPR9,Q9NQC3 4 +Positive regulation of inflammatory response 0.3935785190968284 0.5739305951929233 0.5660147683428542 1.0 0.727468330159282 14 Q08722,Q99735,P53634,P05067 4 +Pyridine containing compound catabolic process 0.4106252603236742 0.5736387264011356 0.56621229994543 1.0 0.727468330159282 4 Q9BQG2 1 +Phosphatidylglycerol biosynthetic process 0.4105300811013431 0.5731686324900297 0.5665305206676319 1.0 0.7277357067234945 4 Q9HCL2 1 +Positive regulation of ubiquitin dependent protein catabolic process 0.3286447074458325 0.5695449966365602 0.5689863435104239 1.0 0.7303225372422589 31 P31749,Q9UMX0,P04062,O43765,P49841,Q96JB5,P10909,Q8IXJ6,Q96HY6,P0DMV9,P51572,O60826,Q9UBS8,Q9UNE7,Q9BW61 15 +T cell chemotaxis 0.4388735222642619 0.5682978067587834 0.5698327680254978 1.0 0.73112049293568 5 O95747,P78536 2 +Lymphocyte chemotaxis 0.4388735222642619 0.5682978067587834 0.5698327680254978 1.0 0.73112049293568 5 O95747,P78536 2 +Positive regulation of nucleobase containing compound transport 0.3750740082889224 0.5678141847882148 0.5701611470102126 1.0 0.73112049293568 3 Q16630,Q07666 2 +Positive regulation of rna export from nucleus 0.3750740082889224 0.5678141847882148 0.5701611470102126 1.0 0.73112049293568 3 Q16630,Q07666 2 +Protein k11 linked ubiquitination 0.4459940202874491 0.5616156464756727 0.5743779177063653 1.0 0.7358138511574661 8 Q9UJX3 1 +Negative regulation of protein containing complex assembly 0.3209194106164285 0.5583935133661624 0.5765757012717838 1.0 0.7378902647533956 40 P16949,P45880,P04062,P10909,Q8IXJ6,O00571,Q9NUQ9 7 +Positive regulation of cellular carbohydrate metabolic process 0.4667088832287235 0.5582573464539615 0.5766686665836418 1.0 0.7378902647533956 6 P31751 1 +Positive regulation of glucose metabolic process 0.4667088832287235 0.5582573464539615 0.5766686665836418 1.0 0.7378902647533956 6 P31751 1 +Regulation of chromatin assembly 0.390521843573174 0.5555321602475717 0.5785307189629436 1.0 0.7398431736892597 14 Q9UK61,Q8NEY8 2 +Regulation of lipid localization 0.3375689340779407 0.5551896555313249 0.578764943731249 1.0 0.7398505284010808 27 Q8WTV0,P14174,O15260 3 +Positive regulation of ion transport 0.3122959731167092 0.5538520948791791 0.5796800724396975 1.0 0.7401672331441193 47 Q99996,P05026,O00483,P31749,P33176,Q15041,P54652,P54709,P51809,P14174,P0DP25,Q4KMQ2,Q07812,O43865,O76024,Q00535,P20020,P30536,P08183,P55011,Q13642 21 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.3692536285369215 0.5526408649230362 0.5805093537099286 1.0 0.7409122232383861 17 O60313,P46379,Q07812,O95831,P18031,O95881 6 +Signal transduction in absence of ligand 0.3900024073034757 0.5524146817409111 0.5806642739473304 1.0 0.7409122232383861 14 P31749,O95677,Q07820,P49841,Q07812,O43464 6 +Antigen processing and presentation of exogenous antigen 0.4440649199547277 0.5523450719272296 0.5807119558745408 1.0 0.7409122232383861 8 Q9UIQ6,P04439 2 +Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.4323838342824322 0.5518430657793931 0.5810558786271978 1.0 0.7410736361850322 9 O43464,Q9UL15 2 +Positive regulation of interferon gamma production 0.4055532046151929 0.5487040673688528 0.5832085544425343 1.0 0.7428762127416714 4 Q9NUQ9 1 +Intermediate filament organization 0.4432599628954151 0.5484854530884177 0.5833586150768038 1.0 0.7428762127416714 8 P07196,P08670 2 +Ossification 0.2795725300914038 0.547292219896206 0.5841779880552511 1.0 0.7433254376313351 70 P31749,Q9NX62,Q15125,O60506,P22413,O95747,Q9UBG0,O75844,P06576,P67936,P38159,Q96A33,P07910 13 +Positive regulation of dephosphorylation 0.382522574825423 0.5467379657943299 0.5845587670466399 1.0 0.7434553526242186 15 Q86XL3,P04062 2 +Regulation of vacuole organization 0.3890166935704171 0.5465062081612264 0.5847180214482197 1.0 0.7434553526242186 14 Q14108 1 +Inositol phosphate catabolic process 0.4339664941739213 0.5454300845290316 0.5854577539516561 1.0 0.743951220124302 5 Q10713 1 +Heart valve morphogenesis 0.4336492890995118 0.5439587404693244 0.5864698656025924 1.0 0.744854303675273 5 O75116,P20248,O94813,P42345 4 +Protein autoprocessing 0.433542525068557 0.5434637122143531 0.5868105690805987 1.0 0.744854303675273 5 O43464 1 +Regulation of p38mapk cascade 0.3703374777975242 0.5429027762377587 0.5871967443742467 1.0 0.7450588758768854 3 P15311,Q99873 2 +Negative regulation of translational initiation 0.4420832170752267 0.5428525860579662 0.5872313034411705 1.0 0.7450588758768854 8 Q9BPZ3,P60228,Q9BWF3 3 +Endothelial cell migration 0.3199688662987921 0.5415635486776916 0.58811920848644 1.0 0.7457567138491731 39 P09601,Q8WTV0,P57105 3 +Negative regulation of protein polymerization 0.3374353056667782 0.5412268963047897 0.5883512010028025 1.0 0.7459069801318859 26 P16949,P45880 2 +Very long chain fatty acid catabolic process 0.4329379603775385 0.5406623924569782 0.5887403044672532 1.0 0.7460900225023808 5 Q15067 1 +Embryonic organ morphogenesis 0.3408979350700529 0.5388074073364163 0.5900197519612513 1.0 0.7473055846515734 23 P54802 1 +Dendritic cell migration 0.4321682464454837 0.5371003892887257 0.5911982719203075 1.0 0.7483680097914791 5 Q4KMQ2,Q07021,P60953,P09429 4 +Regulation of carbohydrate catabolic process 0.3933147829185626 0.5356749765330112 0.5921832007828147 1.0 0.7491234567803554 13 Q14108 1 +Protein localization to microtubule organizing center 0.3871586278670146 0.5353958191044931 0.5923761805685872 1.0 0.7491416336352456 14 P25054,P49841,Q15154,Q8WXW3,Q15691,P37198,Q9P2S5,Q9BV73 8 +Regulation of oxidative stress induced cell death 0.3510761039488513 0.5349562494352824 0.5926801107995319 1.0 0.7493826003968063 19 P31749,Q9UL15,Q9UMX0,Q07820,P23246,O43464 6 +Positive regulation of mrna processing 0.342012254402333 0.5340313841918568 0.5933198207337989 1.0 0.7500479524157759 21 Q14011,P62995,P98179,P38159,Q13595 5 +Protein lipid complex assembly 0.4024281907017962 0.5334639342853543 0.5937124704200905 1.0 0.7504007873410553 4 Q9Y5X1,O95573,P35610 3 +Neuromuscular junction development 0.4038692469315741 0.5325828670262129 0.5943223646926588 1.0 0.7509460574970496 11 O15258,Q14696,P46934,P05067 4 +Regulation of chondrocyte differentiation 0.4020762491999768 0.5317536733938447 0.5948966123684594 1.0 0.7511791576505823 4 P16435 1 +Regulation of cellular protein catabolic process 0.2677955226835821 0.5308612622865523 0.595514923462904 1.0 0.7516726755474279 95 P31749,Q9UL15,Q05086,Q9UMX0,P46379,P49069,P04062,Q9UL46,P24941,Q9Y297,P10909,Q96HY6,Q9H2J4,P61289,P51572,Q9UBS8,Q9BW61 17 +Cellular response to retinoic acid 0.3923958235579712 0.5303596285500909 0.5958626113364418 1.0 0.7517420989991893 13 O43464,O95747,P49841,P16220 4 +Smooth muscle cell proliferation 0.3503054373583674 0.5295073708364573 0.5964535326281766 1.0 0.751885512675883 19 P09493,P09601 2 +Tor signaling 0.3372209784476771 0.5283126687031497 0.597282340088217 1.0 0.7527534297564886 25 Q9NWS0,P31749,O75340,Q9P2J5,P04062,Q15382,Q9H4A6,Q6IAA8,O75844,Q9UHA4 10 +Postsynaptic modulation of chemical synaptic transmission 0.4012437074326176 0.5277129417973895 0.5976985893508444 1.0 0.7528473369582123 4 Q08209,P06730,Q7L576 3 +Regulation of translation at synapse modulating synaptic transmission 0.4012437074326173 0.5277129417973876 0.5976985893508457 1.0 0.7528473369582123 4 Q7L576,P06730,P35268 3 +Positive regulation of proteasomal ubiquitin dependent protein catabolic process 0.3297593892252144 0.52731090148576 0.5979777051063424 1.0 0.7530553835838066 29 P31749,Q9UMX0,P04062,P10909,Q96HY6,P51572,Q9UBS8,Q9BW61 8 +Vesicle mediated transport to the plasma membrane 0.293735090784207 0.5262079472388025 0.5987437328615233 1.0 0.7537328248536777 58 Q9H4A5,Q15907,Q13277,Q96C92,Q9H4A6,P98194,Q9H223,Q567U6,Q4J6C6,Q96L92,O43752,Q9BZG1 12 +Myeloid cell activation involved in immune response 0.4272012747899378 0.5260120408164932 0.5988798410252716 1.0 0.7537605921416911 9 P09601,Q99584 2 +Nuclear envelope organization 0.3170406431994814 0.5241194138394898 0.6001954864061503 1.0 0.7549851483932712 35 Q9H6H4,O43633,Q9BTV4,Q8IXJ6,Q8N1F7,O75844,Q86XL3,P50402,Q6NUK4,O94901 10 +Lipid droplet organization 0.4266347623063671 0.5232028108108795 0.6008331256136601 1.0 0.7556434114520798 9 Q14534 1 +Adiponectin activated signaling pathway 0.3661930136175255 0.5213201625144992 0.6021437576136508 1.0 0.7570862405474407 3 Q06481,P33121 2 +Neural nucleus development 0.3491087858535495 0.5210613694845694 0.6023240206988112 1.0 0.7570862405474407 19 O75489,P62258,P24539,Q8IXJ6,O15027,P0DP25 6 +Protein localization to extracellular region 0.2753327086122175 0.5130453603906864 0.6079195910358974 1.0 0.7620903977913972 71 Q9H4A5,Q96PC5,Q9UBV2,Q5T9L3,P53985,Q96KC8,Q32P28,P49755,Q9H4A6,Q86YV9,Q16850,O43768,Q8N5M9 13 +Genomic imprinting 0.3643292529698576 0.5116833134133905 0.6088726663805315 1.0 0.7629957247077992 3 Q13263 1 +Negative regulation of proteasomal protein catabolic process 0.336244512756106 0.5110877234182135 0.6092896319140695 1.0 0.7633734933308218 24 Q9UL15,P49069 2 +Pigment cell differentiation 0.4558430867796767 0.5104716913355564 0.6097210422640802 1.0 0.7637692131014605 6 P22413 1 +Regulation of mitochondrial membrane potential 0.3388054635844988 0.510178668483666 0.6099262952608604 1.0 0.7638815397724136 21 P31749,Q9BSK2,P31751,P30536,O75915,Q8IWA4 6 +Pore complex assembly 0.3822784646216349 0.5063910463454223 0.6125821588583586 1.0 0.7656914410948724 14 Q9BTX1,Q9NQC3 2 +Positive regulation of nucleocytoplasmic transport 0.3297002663030581 0.5039531123544675 0.6142943261733147 1.0 0.7671714288887825 28 Q13263,Q9Y3B8,Q9C0E2,P62258,P49841,P46934,P06493,P50402 8 +Neuron cellular homeostasis 0.4440138605339463 0.5020849648858338 0.6156077557891209 1.0 0.7682926953193778 7 Q00535,P51790 2 +Oligodendrocyte progenitor proliferation 0.3959135327213371 0.502014741426794 0.6156571515223823 1.0 0.7682926953193778 4 Q8IXJ6,P19022,P98164 3 +Response to osmotic stress 0.3372983540338443 0.4990164337976369 0.6177678067754808 1.0 0.7699090015046488 21 O95202,Q9BPX6,P30536,O95747,O00571,P08183 6 +Regulation of neutrophil chemotaxis 0.4430942501481939 0.4979364060332752 0.6185288660672184 1.0 0.7707090998082127 7 O94813,Q8NHP6,Q8NE86,O00429,Q07021,Q00013 6 +Regulation of protein localization to plasma membrane 0.3141985856616924 0.4945138036145389 0.6209433602208689 1.0 0.7728464534274432 34 P31749,Q13277,O15400,O00264,Q13501,P98194,O15258 7 +Response to molecule of bacterial origin 0.3134460073605365 0.4940963188086659 0.6212381575338655 1.0 0.7729222483323261 41 P31749,Q8WTV0,Q13151,P08670,P30536,Q8IXJ6,Q86U42,Q9Y263,Q9NUQ9,P78536,Q86UE4,P14174 12 +Secretory granule localization 0.3605683836589644 0.4923732887592866 0.6224554786834522 1.0 0.7739294770036365 3 P33176,O60763 2 +Osteoblast proliferation 0.3938406870002905 0.4921041748133171 0.6226457011076991 1.0 0.7739294770036365 4 Q9Y251,P61586,P20248 3 +Regulation of osteoblast proliferation 0.3938406870002905 0.4921041748133171 0.6226457011076991 1.0 0.7739294770036365 4 Q9Y251,P61586,P20248 3 +Regulation of cholesterol metabolic process 0.4416123295791363 0.4912669561264552 0.6232376478026715 1.0 0.7740984052486104 7 P16435,O75477,O94905,Q13131,Q9UBM7,P49748 6 +Regulation of extrinsic apoptotic signaling pathway 0.31403894566156 0.4906754679599615 0.6236560001225597 1.0 0.7744724736583987 33 P31749,P09601,Q07820,O00571,Q9NQX7,O43464 6 +Semaphorin plexin signaling pathway 0.4198877872125427 0.4899771051310632 0.6241500999013567 1.0 0.7745039448456753 9 P42892 1 +Regulation of receptor signaling pathway via stat 0.4193169851962702 0.4871864726020358 0.6261261908030997 1.0 0.7763729821796784 9 Q9NX40 1 +Positive regulation of cytokine production 0.2883413293569732 0.4862828194928609 0.6267666586189011 1.0 0.7767012223995415 60 P49755,Q99584,P09601,Q9H1D9,Q9NUD5,P05067,P10909,Q8WXW3,O00571,Q9NUQ9,P14174 11 +Medium chain fatty acyl coa metabolic process 0.3270198283515914 0.4858182423497382 0.6270960391472165 1.0 0.7767012223995415 2 P51659 1 +Regulation of protein localization 0.2627670904128388 0.4829318651810789 0.6291441153731845 1.0 0.7785084176186812 245 Q92544,Q15907,Q13277,Q9GZP9,O14737,Q96PU5,Q9BQT9,Q96C92,Q16850,Q96HY6,P06493,P55786,P27105,O43768,P51572,Q9BV73,Q9H4A5,P31749,Q5T9L3,Q96KC8,O00264,Q8N183,Q9BZL1,Q9GZY8,Q9H4A6,P51151,Q9Y282,P49257,Q13438,P18031,Q8N5M9,Q9BXS4,P50402,O43752,P60604,O75116,P50416,Q14C86,P53985,Q32P28,P62258,Q66GS9,Q14696,P31751,P98194,Q9NQC3,Q9NR31,O43464,Q9UII2,Q9BRT2,P49755,Q13263,O15400,Q9Y3B8,Q9C0E2,Q8NE86,Q13501,O60499,Q10713,O15258 60 +Enteroendocrine cell differentiation 0.4483825179050854 0.4782141684103099 0.6324977792076694 1.0 0.7820648368650962 6 P31749,Q15382 2 +Synaptonemal complex organization 0.4385630059027934 0.4776061045303444 0.6329305851807163 1.0 0.7822689930061835 7 Q92791 1 +Protein maturation by protein folding 0.4482142286403317 0.4774921102216782 0.6330117377208457 1.0 0.7822689930061835 6 O00170,O76024 2 +Positive regulation of smoothened signaling pathway 0.4477729905661111 0.4756001495500197 0.6343592688283604 1.0 0.7834072173878259 6 Q9BZG1 1 +Membrane invagination 0.3707980401513885 0.4750249083045235 0.6347692196260235 1.0 0.7834154570510532 15 O43633,Q4KMQ2,P51809,Q9Y5X1,P51790 5 +Positive regulation of membrane permeability 0.393161712930809 0.4748200465095032 0.6349152432690854 1.0 0.7834250934015278 11 Q07812,Q9UII2,P45880 3 +Regulation of adherens junction organization 0.356719952634692 0.472810449846553 0.6363484180484937 1.0 0.784631846060167 3 Q9H3S7,P35611 2 +Membrane repolarization during cardiac muscle cell action potential 0.3891870446916967 0.4700331113013648 0.6383313613583916 1.0 0.7863433303294707 4 P05026,P05023 2 +Membrane repolarization during action potential 0.3891870446916967 0.4700331113013648 0.6383313613583916 1.0 0.7863433303294707 4 P05026,P05023 2 +Negative regulation of cation channel activity 0.4259380965489108 0.4667948741378817 0.6406466435297844 1.0 0.788021452020095 8 Q9UMX0 1 +Hypothalamus development 0.4447699254621146 0.4627704793141346 0.643528893403265 1.0 0.7908297613429116 6 Q07812,O14949 2 +Regulation of myelination 0.3803913756548613 0.4617866311314232 0.6442343388789187 1.0 0.7915494972394077 13 P31749,P53634,Q15058,Q8IXJ6,O75746,Q96P11 6 +Posttranslational protein targeting to membrane translocation 0.3871541195780267 0.4604719277889162 0.6451775166756386 1.0 0.7922664822945551 4 Q99442 1 +Regulation of t cell activation 0.3098291452967519 0.459023270777278 0.646217455178195 1.0 0.7929541703068493 41 P00813,P30825,Q9HCL2,Q08722,Q9NUQ9,O96005 6 +Cellular response to heat 0.3283377226924339 0.4582893456175734 0.6467445776344025 1.0 0.7934536687554792 25 O75340,P09601,P62258,P49841,P05198,P0DMV9,O43464 7 +Schwann cell development 0.4014939492219948 0.4556523935704833 0.6486399606797562 1.0 0.7951885550236522 10 P31749,Q8N3R9,P31751 3 +Autophagosome maturation 0.3540850675347634 0.4536515608828605 0.650079636182038 1.0 0.795920028811984 17 P16615,O95721,O43633,Q9UMX0,P51809 5 +Positive regulation of protein localization to cell periphery 0.3287230977713726 0.4529379652724449 0.6505934119850059 1.0 0.79625404811276 24 P31749,O00264,Q13501,P98194,O15258 5 +Protein folding in endoplasmic reticulum 0.4122182680901541 0.4527633441731505 0.6507191612882697 1.0 0.7962604956404692 9 P27797,P27824,P07237,Q13217,P14625,Q8IXB1,Q9P0L0,Q96HE7 8 +Response to camp 0.4007746837084704 0.4520272215677691 0.6512493720396764 1.0 0.7965405622836986 10 P35613 1 +Epithelial cell differentiation 0.2644719536574544 0.4517116445554621 0.6514767283418532 1.0 0.7965975388735075 119 P31749,Q9NZJ7,Q9Y3B8,P07858,Q9Y6M7,P21796,P31751,P31942,P08670,P07602,P20073,Q16739,O14773,Q13510,Q8NEY8 15 +Development of secondary female sexual characteristics 0.3522794552989873 0.4504988946484162 0.6523507510235271 1.0 0.79717769078123 3 Q99623,Q15648 2 +Positive regulation of tyrosine phosphorylation of stat protein 0.3849570624814837 0.4501958571440252 0.6525692232375562 1.0 0.7971959327868778 4 Q8WXW3,P07948,Q92769 3 +Cell activation 0.2621868949899589 0.4489519830214563 0.653466295412706 1.0 0.797641312507568 139 P00813,P24390,Q99584,Q9BWH2,Q96L92,P31749,P78318,P53634,P04439,P09601,P05067,P11279,Q9NUQ9,P14174,P04062,P55327,Q9HCL2,P10909,Q8WXW3,Q08722,Q96FZ2,P0CG08,P46379,Q92542,P30825,O96005 26 +Phosphatidylglycerol metabolic process 0.3833797416476105 0.4489392088193246 0.6534755106676045 1.0 0.797641312507568 12 Q99623,Q9HCL2,Q96JX3,O95674,Q92604 5 +Regulation of toll like receptor 3 signaling pathway 0.3844854116105524 0.4479977274859552 0.6541548366850283 1.0 0.7980914192374482 4 Q9UMX0 1 +Positive regulation of tumor necrosis factor superfamily cytokine production 0.3830922274220997 0.4473759303532625 0.65460365168336 1.0 0.7983531156994512 12 P14174,P05067 2 +Multi organism reproductive process 0.2623705790407065 0.4459532662020543 0.6556310043066826 1.0 0.7990162838766117 154 Q9BPZ3,P00813,O95470,Q9BTX1,P45880,Q9H2V7,Q15067,Q96QD8,P07858,P35613,P05067,Q15363,Q8N2A8,Q9BQE5,Q9UIQ6,P41208,Q9Y2W6 17 +Ether biosynthetic process 0.4117025315100237 0.4444461845820388 0.6567200287098691 1.0 0.7999009712022714 5 O15228,O00116 2 +Regulation of ion transmembrane transport 0.2747926671208299 0.4433537636026667 0.6575098736186498 1.0 0.8007154513996051 68 Q99623,Q99996,Q9UMX0,Q13642,P62942,Q96PU5,P05026,P21796,P46934,P27105,O00483,Q9BVC6,Q15041,P05067,P54652,P54709,P0DP25,P62258,Q4KMQ2,Q07812,O43865,P0CG08,O75844,O75915,O95747,P08183 26 +Exocytic process 0.345291712192336 0.4426016820446289 0.6580538679191936 1.0 0.800997853098517 18 Q13277,O95721,O15498,Q9P253,Q7L0J3,P51809 6 +Mitochondrial outer membrane permeabilization involved in programmed cell death 0.398795539032482 0.4420835610290351 0.6584287396726729 1.0 0.800997853098517 10 Q07812,Q9UII2,P45880 3 +Cellular response to virus 0.3262233770726463 0.4417960232270924 0.6586368165452794 1.0 0.800997853098517 25 O43657 1 +Positive regulation of epithelial cell proliferation 0.3243623318082119 0.4365363508100657 0.6624476312279877 1.0 0.8039141378600386 26 P31749,P09601,Q9H2J4,O95747,Q9NQC3 5 +Positive regulation of response to external stimulus 0.274132568439817 0.4348443911745873 0.6636753808349749 1.0 0.8048129526492384 68 Q13277,P53634,Q8NE86,Q99538,Q9H1D9,Q99735,Q9NUD5,P05067,P11279,Q08722,O95747,P23246,P51809,P78536,Q9BY67,Q15233,Q96PK6,P14174 18 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.3806826006843588 0.4343165368875462 0.6640585968439066 1.0 0.8048603581593025 12 P67809,O60506 2 +Regulation of membrane lipid distribution 0.4083597983105999 0.4342833223552766 0.664082713143221 1.0 0.8048603581593025 9 Q96AA3,P08183,Q7Z3C6,Q4KMQ2 4 +Interferon gamma mediated signaling pathway 0.4093601895734522 0.4341195867040168 0.664201602874982 1.0 0.8048603581593025 5 P04637,P42224,P08238,Q16543 4 +Cellular response to vitamin d 0.4093601895734483 0.4341195867040003 0.664201602874994 1.0 0.8048603581593025 5 Q8TB36,Q13573,O15164,P20020 4 +Mammary gland duct morphogenesis 0.3810279853028792 0.4319714714913722 0.6657621478268609 1.0 0.8063078678738729 4 Q9Y297 1 +Icosanoid biosynthetic process 0.379716066890237 0.4290998472780915 0.6678505634180012 1.0 0.8082447122559183 12 Q99735,P14174 2 +Positive regulation of blood vessel endothelial cell migration 0.3743626745541552 0.428018218574475 0.668637856378046 1.0 0.8086808118078445 13 P09601,P31749,P06576 3 +Labyrinthine layer development 0.407001933892636 0.4278205477312701 0.6687817759169916 1.0 0.8086808118078445 9 Q15363 1 +Stem cell proliferation 0.379468248940762 0.4277643229730673 0.6688227140780265 1.0 0.8086808118078445 12 P04062 1 +Heart morphogenesis 0.3070153807854207 0.4273420814614009 0.6691301864462527 1.0 0.808904591590138 33 P09493,Q15363,Q9NQC3,O75844 4 +Negative regulation of calcineurin mediated signaling 0.3793307669529037 0.4241616667578773 0.6714479148538115 1.0 0.8106684817809353 4 Q99653,P49841,P42345 3 +Negative regulation of calcium mediated signaling 0.3793307669529037 0.4241616667578773 0.6714479148538115 1.0 0.8106684817809353 4 Q99653,P49841,P42345 3 +Lipid import into cell 0.426312405157981 0.4236345606558326 0.6718323463819742 1.0 0.8109687309779717 7 P31751 1 +Anaphase promoting complex dependent catabolic process 0.3950612502992983 0.4234508847050922 0.6719663259746564 1.0 0.8109687309779717 10 Q9UJX3,P24941 2 +Regulation of smoothened signaling pathway 0.3677776920759 0.421912763064404 0.6730886937763738 1.0 0.8117064814873166 14 Q9Y297,P22413,Q9BZG1 3 +Stress granule disassembly 0.3463587921847206 0.4212125337709045 0.6735998927732834 1.0 0.8119317328722652 3 P33176,Q07866 2 +Negative regulation of ubiquitin dependent protein catabolic process 0.3222668013602334 0.419998834873608 0.674486304851067 1.0 0.8128519308462258 26 Q96HY6,Q9UL15,Q9H2J4,P49069 4 +Glycerolipid metabolic process 0.2742752201680667 0.4184327639849127 0.675630735752109 1.0 0.814082685977336 67 O60762,Q9UBV2,Q9NX62,Q9Y2B2,P48651,Q8IY17,Q92604,Q86UL3,Q9HBU6,O95674,Q9NPH0,P50416,Q9UG56,Q9BVG9,Q9HCL2,Q96JX3,Q8WTV0,Q8N2K0,P35790,Q96N66,Q10713,O43292 22 +Vesicle localization 0.2793420899315125 0.4179082359664974 0.6760142106640754 1.0 0.8143962665473704 63 O95721,P49755,O15498,Q9BVK6,Q92905,Q15363,O95772,Q14849,Q9NR31 9 +Regulation of tissue remodeling 0.4337777777777809 0.4165478904450155 0.6770091312906446 1.0 0.815297621847644 6 Q08209,P02786,O75116,P41240,P04637 5 +Phosphatidylcholine metabolic process 0.3667657234191853 0.4161236833670069 0.6773195005118686 1.0 0.8153742402336867 14 Q96N66,P35790,Q8WTV0,Q86UL3 4 +Isoprenoid metabolic process 0.3201365726948803 0.4133379904691778 0.6793589995025093 1.0 0.8167095499385926 27 O60762,P51648,Q9Y394,Q6NUM9,P61916,Q9HB40,O43464 7 +Glycerophospholipid metabolic process 0.2831419499216633 0.4131105426603869 0.6795256255889068 1.0 0.8167095499385926 59 O60762,Q9NX62,Q9Y2B2,P48651,Q8IY17,Q92604,Q86UL3,Q9HBU6,O95674,Q9NPH0,Q9UG56,Q9BVG9,Q9HCL2,Q96JX3,Q8WTV0,Q8N2K0,P35790,Q96N66,Q10713,O43292 20 +Modulation by host of viral genome replication 0.4141916985236215 0.4130877586857487 0.679542317773397 1.0 0.8167095499385926 8 P35232,Q9H6S0,P11142,P27105 4 +Regulation of chromatin assembly or disassembly 0.3604189492842297 0.4130136832573064 0.6795965886139039 1.0 0.8167095499385926 15 Q9UK61,Q8NEY8 2 +Axonal transport of mitochondrion 0.4044641855239817 0.4127395015582953 0.6797974803479119 1.0 0.8167095499385926 5 P07196 1 +Organophosphate biosynthetic process 0.2612653425945225 0.41239741535468 0.6800481572931822 1.0 0.8167095499385926 163 P56385,P00813,O60762,P50897,Q9NX62,Q8TB61,Q13232,Q9Y2B2,P48651,O15269,P00846,O75874,P06576,P43490,O75964,Q8WVC6,P00403,Q92604,Q8TBX8,Q9BQG2,Q86UL3,Q9HBU6,Q9NPH0,O95674,Q9UMR5,Q9UKU0,Q9UG56,Q9BVG9,P24539,Q96JX3,Q9HCL2,P36542,Q53GQ0,Q86YN1,P09622,P35790,Q96N66,Q10713,O43292,P56134,Q06203 41 +Multicellular organismal signaling 0.3231769038926203 0.4106326378539541 0.6813419278296826 1.0 0.8179816168985237 24 P16615,P05023,P04062,P05026,O75844,P0DP25 6 +Phenol containing compound catabolic process 0.3125184965966346 0.408171461032419 0.683147798852517 1.0 0.8190546166222665 2 P21964 1 +Neuronal stem cell population maintenance 0.4317037037037057 0.4079640561709582 0.6833000637474078 1.0 0.8190546166222665 6 Q9UIS9,Q15154,Q9BXW9,Q9BXP5,Q9NZI8 5 +Rna secondary structure unwinding 0.3751850755108 0.4052496703573729 0.6852939976614989 1.0 0.8207879721900773 4 O00571,Q9H2U1,Q13838 3 +Response to catecholamine 0.364539941745473 0.4034443655073101 0.6866213546625344 1.0 0.8215923335549291 14 Q8IXJ6,Q92542,P49841,P05067 4 +Skeletal muscle contraction 0.374598659702902 0.4025938452888456 0.6872470381339149 1.0 0.8215923335549291 4 P10253 1 +Fungiform papilla morphogenesis 0.3425103611604475 0.4024769718914415 0.6873330325654665 1.0 0.8215923335549291 3 Q92769,P35222 2 +Tongue development 0.3425103611604475 0.4024769718914415 0.6873330325654665 1.0 0.8215923335549291 3 Q92769,P35222 2 +Fungiform papilla development 0.3425103611604475 0.4024769718914415 0.6873330325654665 1.0 0.8215923335549291 3 Q92769,P35222 2 +Tongue morphogenesis 0.3425103611604475 0.4024769718914415 0.6873330325654665 1.0 0.8215923335549291 3 Q92769,P35222 2 +Hair follicle placode formation 0.3425103611604475 0.4024769718914415 0.6873330325654665 1.0 0.8215923335549291 3 Q92769,P35222 2 +Eyelid development in camera type eye 0.3425103611604461 0.4024769718914343 0.6873330325654718 1.0 0.8215923335549291 3 P00533,Q92769 2 +Defense response to gram positive bacterium 0.4014645215665825 0.3997825012431545 0.6893167203422013 1.0 0.8232482449204914 5 P04439 1 +Fatty acid derivative biosynthetic process 0.3520706730400031 0.3997493101303865 0.6893411692222726 1.0 0.8232482449204914 16 Q9UMR5,P50897 2 +Extracellular vesicle biogenesis 0.3899902394606179 0.398431913395455 0.6903118375444097 1.0 0.8238539485233263 10 O43633,O14964,Q92905,Q99816,P51149 5 +Inositol phosphate metabolic process 0.4292392784359305 0.3978247145328911 0.6907593981276392 1.0 0.8240485310876475 6 Q10713 1 +Negative regulation of protein secretion 0.4003225426485328 0.3963536673291294 0.6918441412325678 1.0 0.8248958920090277 9 Q16850 1 +Hindbrain morphogenesis 0.377773059566318 0.3942058220243201 0.6934290876531399 1.0 0.8260405263697913 11 Q7Z4L5,Q00535,P04062,Q15058,O15228 5 +Cardiac muscle cell membrane repolarization 0.4193438791904953 0.3936424886168078 0.6938450073341145 1.0 0.8263870343253131 7 P05026,P05023,O75844 3 +Positive regulation of pattern recognition receptor signaling pathway 0.3889059700172965 0.393126604713177 0.6942259750683171 1.0 0.8266917962570284 10 Q9NUD5,Q9NQC3 2 +Gdp metabolic process 0.3997814069385207 0.3925612366226536 0.6946435744140191 1.0 0.8269009598502572 5 Q14168 1 +Regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.3771678728901461 0.3911010543244996 0.6957225413456289 1.0 0.8272814457994353 11 P31749,O43464 2 +Dna methylation dependent heterochromatin assembly 0.3724883472269151 0.3905021121379464 0.6961652937790568 1.0 0.8276590082003572 12 Q9UK61 1 +Peptidyl asparagine modification 0.3989345677666343 0.3898849986057189 0.6966215872332397 1.0 0.8279036270498977 9 P46977,P04843,Q9H0U3 3 +Protein localization to cell periphery 0.2581295899803009 0.3889623702485952 0.6973039829510845 1.0 0.8285656280697082 102 Q13277,P05026,Q5VZ89,Q9H4A5,P31749,O00264,P35613,Q9H4A6,Q4J6C6,Q9BXS4,P98194,Q8N3R9,P31751,Q15363,Q9BZG1,O15400,Q13501,Q9H223,O75915,O15258 20 +Skeletal system development 0.2848704483925803 0.38801017468969 0.6980085040333548 1.0 0.8289556519598278 54 O95470,Q32P28,Q9NX62,P16435,Q15125,Q92896,Q96HY6,O75844,Q7RTS9 9 +Protein destabilization 0.3761981728044779 0.3861373776892919 0.6993949290513222 1.0 0.8299416256229268 11 Q9BUN8 1 +Regulation of glucan biosynthetic process 0.4259577273636549 0.3844273875391214 0.7006617048064081 1.0 0.8307630439658326 6 P22413,P31751 2 +Regulation of glycogen metabolic process 0.4259577273636549 0.3844273875391214 0.7006617048064081 1.0 0.8307630439658326 6 P22413,P31751 2 +Response to axon injury 0.336382024324464 0.3841399240678469 0.7008747421507926 1.0 0.8308665777353522 18 P07196,P00374,Q07812,Q96G23,P30536,P10586 6 +Regulation of protein autophosphorylation 0.3756288198350008 0.3832294401742244 0.7015496511458641 1.0 0.8313256683414945 11 P22413,Q15375,P0DP25 3 +Hyperosmotic response 0.4074136452010595 0.3828138933571303 0.7018577593788606 1.0 0.8313256683414945 8 O95202 1 +Appendage morphogenesis 0.3551922184362552 0.3823945208689575 0.7021687538609998 1.0 0.8313256683414945 15 O95747,Q9NX62,P42892 3 +Positive regulation of exocytosis 0.3491108850094133 0.3818534844891566 0.7025700444325724 1.0 0.8314910010523184 16 O43633,Q00535,P20339,P51151,O14964,P11279,Q99816,P51809,P51149 9 +Cerebellar cortex morphogenesis 0.407166552636637 0.3817209017473091 0.7026683946576744 1.0 0.8314910010523184 8 Q15058,P04062 2 +Regulation of protein targeting to membrane 0.3704847030824633 0.3799372601628913 0.7039919879746828 1.0 0.8321736806518831 12 P31751,P27105 2 +Regulation of nucleotide metabolic process 0.3546434092491047 0.3792052125104994 0.7045354811106981 1.0 0.832518325524871 15 P00403 1 +Positive regulation of actin cytoskeleton reorganization 0.4242183751696859 0.3773756145375894 0.7058944863156396 1.0 0.8338260339696267 6 Q9UQB8 1 +Protein deneddylation 0.3958462918493501 0.3755825138849176 0.7072272924819303 1.0 0.8340587394741393 9 Q92905,Q99627 2 +Regulation of lymphocyte migration 0.3956522777986975 0.3746882343213207 0.7078923435165623 1.0 0.8345452191047021 9 P31749,O95747,P78536,P05067 4 +Positive regulation of wnt signaling pathway 0.3194944848204973 0.3729660348647204 0.7091737232389457 1.0 0.8354597391953996 22 Q5T9L3,Q9H2V7 2 +Stress granule assembly 0.3474754352945778 0.3720291386169303 0.709871154485662 1.0 0.8356669447900279 16 Q14011,P31483,Q14157,P05198,O00571,Q7Z739 6 +Glial cell differentiation 0.2958840778018897 0.3719126213912131 0.7099579076245561 1.0 0.8356669447900279 46 P31749,Q7Z4L5,Q92542,P04062,Q8N3R9,P31751,P05067,P10909,P08670,Q8IXJ6,P06493 11 +Centromeric sister chromatid cohesion 0.4228148148148172 0.3717106821090807 0.7101082708338322 1.0 0.8356669447900279 6 P35222,P49711,P41227,Q9GZZ1,P30153 5 +Positive regulation of catabolic process 0.2586309026265335 0.3703759773031015 0.7111023704651576 1.0 0.8365389046643337 157 Q9UMX0,Q96PU5,Q13190,P21796,P46934,O15269,Q15024,Q96HY6,Q7Z739,P51572,Q9BW61,P31749,P25054,Q969T7,Q13868,P11940,P53634,P27544,P09601,Q8TBX8,P05067,P18031,Q9BXS4,Q96J02,Q92945,O60506,Q86UE4,Q8NF37,O75116,P50416,P04062,Q96JB5,P31751,P10909,Q07812,Q9Y5X1,Q9UII2,P0DMV9,P12235,P46379,P49815,P67809,P49841,Q14103,Q8IXJ6,P51149,Q9UBS8,O60826,P27361,Q9UNE7 50 +Positive regulation of immune response 0.2683531049426551 0.3697390449786867 0.7115769364929916 1.0 0.8369482066706142 78 P00813,Q99623,P01889,Q07666,P04439,Q9H1D9,P11279,P51809,Q9NUQ9,Q15233,P10909,Q07812,Q08722,Q96FZ2,P46379,O15400,Q9NUD5,P23246,Q9BY67,Q96PK6 20 +Negative regulation of neural precursor cell proliferation 0.3942535545023603 0.3691008532390197 0.7120525529914004 1.0 0.8372096286639681 5 P04637,Q13418,Q8IXJ6,Q06481 4 +Intrinsic apoptotic signaling pathway by p53 class mediator 0.3195122984969568 0.3681382208971601 0.712770172852287 1.0 0.837405797835534 20 P61978,Q8N2F6,P46379,P14174 4 +Positive regulation of phosphatase activity 0.4219259259259292 0.3681349375008032 0.712772620982949 1.0 0.837405797835534 6 P42345,Q15257,O14974,Q13464,P0DP25 5 +Morphogenesis of a branching structure 0.318777877493135 0.3677955840935005 0.7130256619726931 1.0 0.83744675747895 22 Q15363,Q9NQC3 2 +Activin receptor signaling pathway 0.3663014509919997 0.3655547379791889 0.7146973545851705 1.0 0.8386780568986846 4 O00255,Q9Y2U8,P62942 3 +Regulation of activin receptor signaling pathway 0.3663014509919997 0.3655547379791889 0.7146973545851705 1.0 0.8386780568986846 4 O00255,Q9Y2U8,P62942 3 +Toll like receptor signaling pathway 0.3521420709863105 0.3647336647138356 0.715310226412806 1.0 0.8390992698548516 15 Q9UMX0,Q9NQC3,Q9NPR9 3 +Positive regulation of mitochondrial fission 0.4124277559286032 0.3644344411124603 0.715533620853847 1.0 0.8391034680758852 7 Q9GZY8 1 +Microtubule anchoring 0.3674071924552363 0.3638307994319084 0.7159843619594228 1.0 0.8392344739195603 12 O95684,P49841,O75381,Q8TD16 4 +Neuron projection arborization 0.3932384341636973 0.3636048233533402 0.7161531244708801 1.0 0.8392344739195603 9 O14641,Q9UPN3,Q9HCE1,P98164,Q13641,Q9NZI8,Q13464,Q15334 8 +Establishment of protein localization to plasma membrane 0.3101530710730417 0.3635089757919451 0.7162247091351386 1.0 0.8392344739195603 29 Q9H4A5,Q13439,Q9H4A6,P41240,P98194,P61026,P51149,Q4J6C6,O15027,Q9HD26,Q9BZG1 11 +Negative regulation of sodium ion transport 0.392647080340707 0.3623589026124124 0.717083846593966 1.0 0.8392344739195603 5 O95747,P46934 2 +Negative regulation of cell development 0.3167295344006244 0.3621620108727015 0.7172309662672811 1.0 0.8392344739195603 24 P30536,Q96G23 2 +Negative regulation of hydrolase activity 0.2684565080585539 0.3621313381313605 0.7172538862215447 1.0 0.8392344739195603 68 P31749,P49755,P16435,Q9Y3B8,Q15041,P07858,P05067,Q96K76,Q15363,O00571,Q15392 11 +Sensory organ morphogenesis 0.3174203233796246 0.3620291624000675 0.7173302380347399 1.0 0.8392344739195603 23 Q15555,O14641,P35222,Q8NBN7,Q07812,O95747,P54802,O75569,P27361,Q9P273 10 +Potassium ion transport 0.3136203556379128 0.3615982290416797 0.7176522882632894 1.0 0.8393423345948755 27 P33176,P05023,Q96PU5,P05026,P62258,P46934,P24941,Q4KMQ2,O95747,P55011,P54709,Q13642 12 +Protein localization to cilium 0.3393337133810131 0.3606097161511949 0.7183912249591702 1.0 0.8397325089768581 17 Q7Z4L5,Q96A65,P18085,Q96C92,P49841,Q10713,A0AVF1,Q9H4M9,Q8NCM8 9 +Positive regulation of apoptotic signaling pathway 0.3019915522965898 0.3600935943328168 0.7187771429159713 1.0 0.839886516536714 32 P53634,O43324,Q07820,Q07812,Q9NQX7,P23246,O43464,P51572 8 +Regulation of cartilage development 0.3915069667072016 0.3575954847193327 0.7206460578444043 1.0 0.8416936037424022 5 P16435 1 +Perk mediated unfolded protein response 0.410727924223335 0.3573456279191521 0.7208330756819483 1.0 0.8416936037424022 7 Q15363,P18031,P57088 3 +Integrated stress response signaling 0.410727924223335 0.3573456279191521 0.7208330756819483 1.0 0.8416936037424022 7 Q15363,P18031,P57088 3 +Positive regulation of t cell proliferation 0.3660465085152734 0.3567574714909665 0.7212733767229469 1.0 0.8420174083465394 12 P30825,Q9HCL2 2 +Action potential 0.3166610252859906 0.356476930039292 0.7214834260139846 1.0 0.8420174083465394 23 P16615,P05023,Q96PU5,P04062,P05026,P0DP25 6 +Regulation of histone h2b ubiquitination 0.364228605270936 0.356464679927143 0.7214925984969667 1.0 0.8420174083465394 4 Q5VTR2,O75150,P50750 3 +Xenobiotic transport 0.3640619549033378 0.3557368065396713 0.7220376781155717 1.0 0.8425047695384558 4 P08183 1 +Positive regulation of nf kappab transcription factor activity 0.3155054713777659 0.353054149950192 0.7240478452617807 1.0 0.8444670330117879 24 P10909,Q96HY6,P05067 3 +Nuclear membrane reassembly 0.3500573673264181 0.3527555281843393 0.7242717264512177 1.0 0.8444670330117879 15 Q9H6H4,O43633,Q6NUK4,Q86XL3 4 +Regulation of phagocytosis 0.3554480020157502 0.3524641668307082 0.7244901871333465 1.0 0.8444670330117879 14 Q8WTV0 1 +Regulation of map kinase activity 0.314967349801302 0.349060254113394 0.7270440746867513 1.0 0.8465822110425972 24 P14174 1 +Positive regulation of oxidative stress induced cell death 0.362136684935045 0.3473600364763063 0.7283208526057585 1.0 0.8474423441675103 4 Q07820 1 +Regulation of synapse assembly 0.3786408287344348 0.3437245864715448 0.7310534192191784 1.0 0.8497242433379442 10 P05067,Q9BQT9 2 +Clathrin dependent endocytosis 0.3483863503914099 0.3432104680895028 0.731440130055466 1.0 0.8500129937717813 15 Q5VW38 1 +Inositol lipid mediated signaling 0.315538184412733 0.3420263296830388 0.7323310776578795 1.0 0.8506109125203736 21 P31749,Q05086,P46934,Q10713,Q8NDZ4 5 +Positive regulation of cellular response to transforming growth factor beta stimulus 0.3874407582938318 0.3407543102721561 0.733288549120366 1.0 0.8514237563486471 5 O00560,Q13573,P08238,P78536 4 +Sprouting angiogenesis 0.341447353311717 0.3362341895562003 0.7366942726777699 1.0 0.8537282917985939 16 P09601 1 +Negative regulation of proteolysis involved in cellular protein catabolic process 0.306482257993436 0.3336324220001484 0.7386569495264375 1.0 0.8551031317954502 29 Q96HY6,Q9UL15,Q9H2J4,P49069 4 +Odontogenesis 0.3567532032615945 0.3324503885321401 0.739549195472694 1.0 0.8555274380136838 13 P35613,O95747,Q6P4Q7,Q07812 4 +Endocytic recycling 0.3063346560550374 0.3324373638384673 0.7395590289857452 1.0 0.8555274380136838 29 Q15907,Q15904,Q96C92,P61106,Q9H223,Q567U6,P51149,Q96L92,Q9H3S7,O43752,O60826 11 +Cellular response to sodium arsenite 0.2974252737496386 0.3318379554060068 0.7400116223829567 1.0 0.8556222554809239 2 P09651 1 +Cellular response to salt 0.2974252737496386 0.3318379554060068 0.7400116223829567 1.0 0.8556222554809239 2 P09651 1 +Regulation of dna duplex unwinding 0.3576687603569487 0.3281534965231673 0.742795607023488 1.0 0.8579274162981912 4 Q04837 1 +Myeloid leukocyte migration 0.3080739209455754 0.327825231590694 0.7430438085778253 1.0 0.8579274162981912 28 P35613,P14174,Q8N5M9 3 +Multicellular organismal response to stress 0.394353870990776 0.3261466907199297 0.7443133725592803 1.0 0.8590930980168151 8 P30536 1 +Protein folding 0.255368345233727 0.3253914554268932 0.7448848215526067 1.0 0.8593126770629731 107 Q9UL15,O75718,O95433,Q96KC8,O14737,Q32P28,Q16543,Q14696,O95302,P10909,Q9H2J4,P49257,P40855,O15212,Q9UHV9,Q6ZRP7,Q96A33,P48723 18 +Regulation of gliogenesis 0.3334904137804308 0.3248326247089378 0.7453077513973325 1.0 0.859572761751453 17 P30536 1 +Nik nf kappab signaling 0.3109008353509762 0.3247198739670009 0.7453930918344269 1.0 0.859572761751453 25 O43657,P31749,O00571,P05067 4 +Apical protein localization 0.3568255848386055 0.3245663264763441 0.7455093161384974 1.0 0.859572761751453 4 Q9HD26,P18085,P54920 3 +Production of sirna involved in rna interference 0.3566492733821155 0.3238177640476152 0.7460760064636947 1.0 0.860076107922302 4 O75569,Q99598 2 +Cellular response to abiotic stimulus 0.2625423137064214 0.3230593795601885 0.746650272557766 1.0 0.8605880103477983 70 Q15907,Q15555,P27544,O95202,Q9BPX6,P46934,P31751,Q96K76,P30536,O95747,O75844,Q96QD8 12 +Protein quality control for misfolded or incompletely synthesized proteins 0.3548384683630853 0.3223690858586819 0.7471731010883707 1.0 0.8610404577320038 13 Q9BUN8,P46379 2 +Layer formation in cerebral cortex 0.3561701589518802 0.3217862813023386 0.7476146079271744 1.0 0.8613990487780152 4 Q96N66,P35222 2 +Attachment of mitotic spindle microtubules to kinetochore 0.4017197215388997 0.3204064223304518 0.7486602576560057 1.0 0.8618525767024111 7 Q96DB5 1 +Response to vitamin d 0.4094814814814844 0.3190912682607303 0.7496573047670585 1.0 0.8620993783200795 6 Q8TB36,O15164,P20020,Q13573,Q14258 5 +Cellular response to vitamin 0.4094814814814841 0.3190912682607289 0.7496573047670596 1.0 0.8620993783200795 6 Q8TB36,O15164,P20020,Q13573,Q96C86 5 +Regulation of binding 0.2536976526763329 0.3187245016948081 0.7499354332312311 1.0 0.8622691854949907 102 Q96D46,Q9Y2S7,Q96HY6,P40855,P16615,P16949,P31749,P09601,P05067,Q9BUN8,P0DP25,P60228,Q07812,P50750,O75844,O75503,Q71SY5,P10586,Q13263,P49841,P05198,P35269,Q8IXJ6,O75381,P27361 25 +Response to nerve growth factor 0.3580228603539966 0.3156782975524996 0.7522467010370852 1.0 0.8644754733357845 12 P31749,P05067 2 +Nuclear ncrna surveillance 0.38088768491696 0.3141167211289014 0.7534323901958273 1.0 0.8652469000895899 5 Q15024 1 +Positive regulation of aspartic type peptidase activity 0.3235642391947839 0.3141045198015445 0.7534416568339521 1.0 0.8652469000895899 3 O75116,P07948 2 +Pancreas development 0.3531921086072774 0.3137541073375627 0.7537078024971582 1.0 0.8654021658623555 13 P31749,Q5T9L3,Q15382,O76024 4 +Regulation of phospholipid metabolic process 0.3567776962829517 0.3094043722312382 0.7570139448994471 1.0 0.8684945902710433 12 Q8WTV0 1 +Regulation of epithelial cell migration 0.2894640572413902 0.3081275293513724 0.7579852942517693 1.0 0.8692564306281352 46 P31749,Q15555,P09601,P57105,Q9NQC3,P06576,P42785,Q8WTV0 8 +Regulation of metal ion transport 0.2700029075597208 0.3053907720709721 0.7600685491418451 1.0 0.8704598182864296 63 Q99996,Q9UMX0,P05023,P62942,Q96PU5,P05026,P21796,P46934,P27105,P31749,P33176,P54652,P54709,P0DP25,P35222,P62258,Q4KMQ2,Q07812,O43865,O76024,Q00535,P30536,O95747,Q13642 24 +Regulation of immune response 0.2556026682180753 0.3003429286167975 0.7639155914900875 1.0 0.8734806477781987 127 P00813,Q9UMX0,Q16543,P01889,O00571,O43657,P04439,P09601,Q9H1D9,P11279,Q9NPR9,P51809,Q9NUQ9,Q9NZ08,P10909,Q08722,Q07812,Q96FZ2,Q9NQC3,Q8TCT8,P46379,O15400,Q9NUD5,P23246 24 +Response to virus 0.2673561024418955 0.2998212701848965 0.7643134900238695 1.0 0.8734822506601684 86 P16949,Q9H1D9,Q9NUD5,Q9HCL2,P10909,P35269,P61916,Q9H0P0,O75844,O43657 10 +Columnar cuboidal epithelial cell differentiation 0.3501180478568732 0.2978039691186012 0.7658527850160741 1.0 0.8747876004443889 13 P31749,Q15382,Q9NQ88,Q86UL3 4 +Negative regulation of cellular response to insulin stimulus 0.3681551801765564 0.2949401290186077 0.7680396162184295 1.0 0.8766794168545079 10 Q8TBX8,P22413,P49815,P18031 4 +Regulation of peptidyl tyrosine phosphorylation 0.2921849151522653 0.2918443668360463 0.7704056213044757 1.0 0.8783503648335997 38 Q9BRG1,Q15375,P05067,Q9H223,Q8WXW3,Q9H2J4,P78536,O95684,P14174 9 +Ribosomal small subunit export from nucleus 0.3945506072059215 0.291807497794897 0.7704338122167314 1.0 0.8783503648335997 7 Q86U38 1 +Cardiac muscle contraction 0.3079101364299723 0.2907690731980893 0.7712279398587139 1.0 0.8784980100872526 22 P16615,P05023,Q96PU5,P09493,P10253,P0DP25 6 +Regulation of generation of precursor metabolites and energy 0.2919679029119693 0.2895621134245175 0.7721512548533644 1.0 0.8790952012619958 41 Q9NZ45,P31749,Q99623,O14548,Q8NC60,P14406,Q9BSK2,P49841,P31751,P05067,Q9NQ88,P22413,P54619,P06493,Q9H3K2,Q9BRT2 16 +Response to cadmium ion 0.338052405289411 0.285368373662504 0.7753619347562459 1.0 0.8820636013354556 15 P09601,O15118,P48637 3 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.2896211525668472 0.2814656225153439 0.7783532919431386 1.0 0.8844802108755507 43 P31749,P46379,Q9UMX0,P53634,P04062,P49841,O60826,Q96JB5,P10909,Q8IXJ6,Q96HY6,P0DMV9,P51572,Q9UII2,Q9UBS8,Q9BW61 16 +Negative regulation of axonogenesis 0.3990821879238813 0.2796719087914966 0.779729232150207 1.0 0.8855869557107265 6 Q9NQC3 1 +Response to amine 0.3909912624677322 0.2778878058381357 0.7810984849129572 1.0 0.8862648706663088 7 P0DP25 1 +Negative regulation of binding 0.2900382561944347 0.2724996171390592 0.7852378856170386 1.0 0.8884843667253908 38 P31749,P16615,P09601,P27361,P49841,P35269,Q07812,P40855,P10586,O75381 10 +Endocrine pancreas development 0.3894508337367862 0.2719230893580125 0.78568115720688 1.0 0.8888337500822099 7 P31749,Q15382 2 +Regulation of sodium ion transmembrane transport 0.3244178596895458 0.2706993957340021 0.7866222415989448 1.0 0.8895938389335089 17 O95747,P27105,P46934,Q96PU5 4 +Phosphatidylinositol biosynthetic process 0.3049043752407137 0.2699677622214446 0.7871850550512418 1.0 0.8900780203308225 22 O60762,Q9NX62,Q8TBX8,Q96N66,Q9Y2B2,Q10713,O43292 7 +Pigmentation 0.3398807353162835 0.2686190323092757 0.788222864771337 1.0 0.8909010211447194 14 Q15907,P22413,Q86YV9 3 +Retinol metabolic process 0.3804038984290375 0.268334408746057 0.7884419227080175 1.0 0.8909010211447194 8 Q6NUM9,Q9Y394 2 +Sulfur amino acid biosynthetic process 0.3690210031568253 0.2675736257992747 0.7890275344674329 1.0 0.8913283702651349 5 Q9BV57 1 +Response to purine containing compound 0.3236595016970298 0.266258689720378 0.790039985866628 1.0 0.8917622013390558 17 P35613 1 +Ectodermal placode development 0.3426117856085154 0.2659983215261914 0.7902405017003302 1.0 0.8917622013390558 4 Q92769,P35222,O14786 3 +Negative regulation by host of viral transcription 0.3426117856085137 0.2659983215261848 0.7902405017003353 1.0 0.8917622013390558 4 Q9H1E3,P17980,Q13148 3 +Negative regulation of cellular response to growth factor stimulus 0.3478715810151185 0.2653803901515147 0.7907164411419951 1.0 0.8919346235718459 12 O94813,O75340,Q9Y2U8,Q8N0X7,P46934,P98164,O14964,P18031 8 +Positive regulation of viral life cycle 0.3794314778797893 0.2644187728690104 0.7914572474909221 1.0 0.8926179093289256 8 P07237,Q99816,Q06787,O60684,P52292,Q9H9H4 6 +Cellular carbohydrate catabolic process 0.323255706492266 0.2638997508160576 0.7918571676610888 1.0 0.8927642478799276 17 Q9NUJ1,P10253,Q14108 3 +Positive regulation of cilium assembly 0.3705505786279889 0.263684414214027 0.7920231062724474 1.0 0.8927990293969991 9 Q96C92,Q15555,Q66GS9,Q9P2S5 4 +Trachea development 0.3417223185620238 0.2624584796454321 0.7929679920418233 1.0 0.893102498194344 4 P27361,P35222 2 +Trachea morphogenesis 0.3417223185620238 0.2624584796454321 0.7929679920418233 1.0 0.893102498194344 4 P27361,P35222 2 +Trachea formation 0.3417223185620238 0.2624584796454321 0.7929679920418233 1.0 0.893102498194344 4 P27361,P35222 2 +Smooth muscle cell apoptotic process 0.3867133183994514 0.2614137977623441 0.79377341780389 1.0 0.8937050286654019 7 P98175 1 +Protein refolding 0.3470026067383151 0.2611682952101166 0.793962726592258 1.0 0.8937659104153011 12 Q9UL15,O60884,P62942,P0DMV9,P48723 5 +Positive regulation of stress activated protein kinase signaling cascade 0.3503882866910794 0.2596823273115354 0.795108825857826 1.0 0.8949036495392324 11 P05067 1 +Phagocytosis 0.2879412059929436 0.2585585289799301 0.7959758843974061 1.0 0.8955023886914567 42 Q92544,P51790,P20339,Q14696,Q08722,P51809,Q8WTV0,Q9BZG1 8 +Sensory perception of mechanical stimulus 0.3220464674166645 0.256858832677364 0.7972877513042773 1.0 0.8961032002811667 17 Q9Y6M9,Q9Y5L4,Q14108,O95677,P07686,O76024,Q9Y5J7,Q9Y5J9 8 +Toll like receptor 3 signaling pathway 0.365752720972343 0.2551626371189738 0.7985974873479351 1.0 0.8968446548653362 5 Q9UMX0 1 +Positive regulation of cell division 0.3322881951236622 0.2540662792791124 0.7994443540026432 1.0 0.8974906974016426 15 Q15058,P67809,Q9Y2S7,Q8IXJ6 4 +Insulin secretion involved in cellular response to glucose stimulus 0.368009805124323 0.2530202510077847 0.8002525642108385 1.0 0.8976737585005139 9 Q15907,Q8N183,Q8N5M9 3 +Response to inorganic substance 0.2517333780991446 0.2511337919801538 0.8017106706545447 1.0 0.8989660370471473 112 P07196,Q05086,Q96PU5,P46934,Q86YQ8,P06493,Q99720,O15118,P31749,P36551,P09601,P35613,Q99538,P05067,O60888,Q14168,P0DP25,P50995,P24941,O95831,Q96QD8,P48637,Q92542,P00374,P16220,Q14103,Q9NQ88,P30536 28 +Positive regulation of peptidyl serine phosphorylation 0.3021705937325505 0.2505396321930878 0.8021700596751233 1.0 0.8991760387369218 21 P14174,P05067 2 +Neurogenesis 0.2527418506651364 0.2502450371230196 0.8023978583543177 1.0 0.8992291334300082 297 P07196,Q13277,P50897,Q05086,Q14108,Q96PU5,P42892,P46934,Q16739,Q9NQX7,O15031,O75306,P31749,Q9UL15,P16949,O43251,Q9NR77,O00264,P35613,P05067,P54802,Q32P28,P04062,Q8N3R9,P31751,P08670,P10909,Q96G23,Q9NQC3,O75503,Q8WUJ1,O43464,P10586,O14949,Q9UQB8,Q15555,Q92542,Q9NZJ7,Q9Y6M7,Q96N66,P00374,P30536,Q9NZQ3,Q9UNW9 44 +Regulation of potassium ion transport 0.3082999754498331 0.2475695314891029 0.804467487291876 1.0 0.9006819623093357 19 P33176,Q96PU5,P05026,P62258,P46934,Q4KMQ2,O95747,P54709,Q13642 9 +Oocyte differentiation 0.3571813331368583 0.2459232962330718 0.8057416097364534 1.0 0.9019556739072188 10 Q8N2A8,Q9Y2W6,Q9H6S0 3 +Negative regulation of phosphoprotein phosphatase activity 0.373211406141787 0.2397475700005303 0.8105259546541781 1.0 0.9066683630072078 8 O75116,P49841,P62942 3 +Phosphatidylinositol metabolic process 0.2998393027402317 0.239603671693159 0.8106375180828553 1.0 0.9066683630072078 24 O60762,Q9NX62,Q8TBX8,Q96N66,Q9Y2B2,Q10713,O43292,Q92604 8 +Positive regulation of phosphatidylinositol 3 kinase signaling 0.3879299317058488 0.2391393184870647 0.810997554348843 1.0 0.9067641408715114 6 P46934 1 +Threonine metabolic process 0.3058022498519804 0.2379827747433354 0.8118944542056812 1.0 0.9073613933826716 3 O43175,P52758 2 +Deoxyribose phosphate metabolic process 0.3421468961050665 0.2379194054513519 0.8119436042465003 1.0 0.9073613933826716 12 P00813 1 +Response to temperature stimulus 0.2798181690909466 0.2361230651985873 0.8133371764620088 1.0 0.9081768520497472 48 P09601,O43464,P00403 3 +Histamine secretion 0.334922804668214 0.2359160668051553 0.8134978005953251 1.0 0.9081768520497472 4 P51809 1 +Histamine transport 0.334922804668214 0.2359160668051553 0.8134978005953251 1.0 0.9081768520497472 4 P51809 1 +Histamine production involved in inflammatory response 0.334922804668214 0.2359160668051553 0.8134978005953251 1.0 0.9081768520497472 4 P51809 1 +Protein stabilization 0.2563564540870918 0.2331330702205736 0.8156580759899388 1.0 0.910281024015114 76 Q9UBV2,Q99623,P49069,O95429,P05026,Q16543,Q9H2J4,P40855,O15027,Q9UL15,O75718,P11279,O75569,Q32P28,P10909,Q9NQC3,O76024,P13473,P46379,P16220 20 +Positive regulation of protein localization to early endosome 0.3340242819070138 0.2324786808586128 0.816166243873087 1.0 0.9104020259614324 4 O75116,P15311,P35241 3 +Regulation of protein localization to endosome 0.3340242819070138 0.2324786808586128 0.816166243873087 1.0 0.9104020259614324 4 O75116,P15311,P35241 3 +Extrinsic apoptotic signaling pathway via death domain receptors 0.3231969713180912 0.232405383573671 0.8162231679027445 1.0 0.9104020259614324 16 P09601,Q9NR28,O00571 3 +Xenobiotic metabolic process 0.3442856065833896 0.2315919997534429 0.8168549218703245 1.0 0.9104020259614324 11 P07099,O43169 2 +Response to toxic substance 0.2793560889734611 0.2315745005999881 0.8168685147452404 1.0 0.9104020259614324 48 P07196,P27544,Q99735,P00374,O95831,P07099,O43464,P08183,Q15165 9 +Dorsal ventral pattern formation 0.3856254209488554 0.2310024884610597 0.8173128687992741 1.0 0.910604532924318 6 Q7Z4L5,Q8NCM8 2 +Positive regulation of type i interferon production 0.2989814978801598 0.2301495175500398 0.817975588029727 1.0 0.9110213450098528 20 Q9NUD5 1 +Response to nutrient 0.2952021461629214 0.2277888386980571 0.8198104040441918 1.0 0.9123149266347774 28 P09601,P30536,P53985,O43768 4 +Negative regulation of cellular protein catabolic process 0.2856030912859289 0.221879873067917 0.8244073989933454 1.0 0.915408014104002 32 Q96HY6,Q9UL15,Q9H2J4,P49069 4 +Cellular response to acid chemical 0.3303738087596761 0.2198920699309271 0.8259552124505394 1.0 0.9165107453132328 14 Q9UQB8,Q9P2J5,Q14103,Q6IAA8,Q99729,Q9UHA4 6 +Folic acid metabolic process 0.3751212926191836 0.2182545626011648 0.8272307748088983 1.0 0.9170525350334534 7 Q9H2D1 1 +Positive regulation of multicellular organism growth 0.3751052764060906 0.2181964901605991 0.8272760196503932 1.0 0.9170525350334534 7 Q9HCL2 1 +Regulation of dna templated transcription in response to stress 0.3340815617679795 0.2177111098115554 0.8276542069282402 1.0 0.9173179026645548 13 P09601,P46934 2 +Spinal cord development 0.3377062160176264 0.2171004689493706 0.8281300485128273 1.0 0.917691396817786 12 P07196,O43175,Q8NCM8 3 +Positive regulation of reproductive process 0.3814128265104831 0.2163491777503778 0.8287155783403102 1.0 0.9180323931027672 6 Q8IXJ6,Q9H6S0 2 +Regulation of membrane repolarization 0.380640368977465 0.2136936894019494 0.8307859328054832 1.0 0.91893962006886 6 P62258,O75844,Q96PU5 3 +Cardiac conduction 0.3142325134288294 0.2122422908848512 0.8319180148643368 1.0 0.9200378447520752 17 P16615,P05023,P05026,O75844,P0DP25 5 +Golgi to plasma membrane transport 0.2884739828174072 0.2084557028163444 0.8348731668826654 1.0 0.922445999893234 30 Q9H4A5,Q13439,Q9H4A6,P41240,P98194,Q567U6,Q4J6C6,O15027,Q9HD26,O60826,Q9BZG1 11 +Anterograde dendritic transport 0.2980831843166016 0.2072224307762746 0.8358361502687153 1.0 0.9231352134234524 3 P33176 1 +Granulocyte differentiation 0.3716393362536097 0.2057344762273462 0.8369983264593956 1.0 0.9239555603090271 7 Q8N5M9 1 +Diencephalon development 0.3476700363645281 0.2053081720698533 0.8373313596674821 1.0 0.9241688303344002 10 Q07812,O14949,P16220 3 +Negative regulation of signal transduction in absence of ligand 0.3712232193808722 0.204252481524659 0.8381562013671564 1.0 0.924770339705432 7 Q07820,P31749,O95677 3 +Alcohol catabolic process 0.3347866131252342 0.2036528782106086 0.8386247681223031 1.0 0.9250000401802198 12 Q10713,Q8WTV0 2 +Positive regulation of phagocytosis 0.3629534370071036 0.2005475867845076 0.841052344970471 1.0 0.926728067340754 8 Q12907,Q08722 2 +Immune response regulating signaling pathway 0.2627372325347852 0.1987317696785354 0.8424725710607173 1.0 0.92798353702338 61 P00813,P46379,Q9UMX0,P04439,Q9NUD5,Q08722,O00571,Q9NPR9,Q9NQC3,O43657 10 +Regulation of immune system process 0.2514743788162414 0.1980126520024696 0.8430351648576404 1.0 0.9284484926752452 201 P00813,Q9UMX0,Q16543,P01889,O00571,O43657,P31749,O43251,P53634,P04439,P09601,Q99538,Q9H1D9,P05067,P11279,Q9NPR9,P51809,Q9NUQ9,Q9NZ08,P14174,Q9HCL2,P10909,Q8WXW3,Q07812,Q08722,Q96FZ2,Q9NQC3,Q8TCT8,P46379,O15400,P30825,Q9NUD5,P16220,O95747,P23246,P78536,O96005,Q9GZS3 38 +Negative regulation of response to endoplasmic reticulum stress 0.3214955138232245 0.1975315024810473 0.8434116316407843 1.0 0.9287083428047224 15 O60313,P10909,Q96HY6,P18031,O95881 5 +Ether metabolic process 0.3691549626711556 0.1969321411506202 0.8438806411652178 1.0 0.9290699912478634 7 P07099,O15228,O00116 3 +Regulation of t cell migration 0.3750002655164354 0.1946072257609583 0.8457004458751978 1.0 0.9307634049607296 6 O95747,P05067 2 +Regulation of aerobic respiration 0.3205747242025507 0.1928421837507867 0.847082565642236 1.0 0.9318190206939976 15 P14406 1 +Negative regulation of phosphatase activity 0.3351354386920548 0.190966641429864 0.8485517284350135 1.0 0.9329473829241072 11 O75116,O95429,P49841,P62942 4 +Copii coated vesicle cargo loading 0.3525744311950479 0.190811892357481 0.8486729711211578 1.0 0.9329473829241072 9 Q9NR31 1 +Pallium development 0.2794291318310351 0.1868447421998376 0.8517823653975105 1.0 0.9352737910901164 43 P07196,P62995,Q15058,Q96N66,P62258,P49841,Q8N3R9,Q07812,Q9NQC3,Q96QD8,O14949,O94901 12 +Ribonucleoprotein complex disassembly 0.346563981042646 0.1861771605028914 0.8523058340967313 1.0 0.9353851307780302 5 P33176,Q07866,Q14562,Q9UBB9 4 +Dna catabolic process endonucleolytic 0.3658802697631621 0.1854995001077887 0.8528372723181601 1.0 0.935476404630712 7 Q07812,O95831 2 +Positive regulation of secretion 0.2661257460575818 0.1853847725209427 0.8529272511789046 1.0 0.935476404630712 54 Q9H4A5,Q5T9L3,O43633,Q9H4A6,P20339,P51151,O14964,P11279,P51809,Q9H3S7,P14174,O95563,Q9Y5X3,P00367,P49755,Q00535,Q8NE86,P16220,Q99816,P55011,P51149 21 +Regulation of cation channel activity 0.2922480496789024 0.1851617122077073 0.8531021989985517 1.0 0.935476404630712 22 P05067,Q9UMX0,P27105 3 +Tissue remodeling 0.3138048002216038 0.1820677117851086 0.8555295874532607 1.0 0.93761304230315 16 O14773 1 +Negative regulation of mrna 3 end processing 0.3645524599881465 0.1809197392712436 0.8564305748253018 1.0 0.9381981881353256 7 P18615,O75150,Q6PJT7,O00267,P50750,Q5VTR2 6 +Cell cell signaling by wnt 0.2494249848465356 0.1794635971508706 0.8575736985201097 1.0 0.9386330122993772 73 Q5T9L3,Q9H2V7,P20339,Q9NPI1,P05067,Q96K76,Q9Y297,Q9GZS3 8 +Negative regulation of oxidative stress induced cell death 0.325954433435604 0.1793289599359727 0.8576794086789483 1.0 0.9386330122993772 13 O43464,Q9UL15 2 +Regulation of platelet derived growth factor receptor signaling pathway 0.2907045589105944 0.1792482652148803 0.8577427672125266 1.0 0.9386330122993772 3 Q07954,O14964 2 +Embryonic organ development 0.2632321469804674 0.1787672780939637 0.8581204396456841 1.0 0.9388045001851226 58 Q15363,P00813,P54802 3 +Regulation of translation in response to stress 0.3252595189761028 0.1761220571472614 0.8601980526808615 1.0 0.9402991945365224 13 Q15363,O00571,Q9BWF3 3 +Ear development 0.2895281517207616 0.1743176429182402 0.8616158344704044 1.0 0.9415375413384428 26 P42892,P54802 2 +Spinal cord motor neuron differentiation 0.2892243931320241 0.1738111800470095 0.8620138577295899 1.0 0.9416610885512166 3 Q9ULW3,Q8NCM8 2 +Cell differentiation in spinal cord 0.2892243931320241 0.1738111800470095 0.8620138577295899 1.0 0.9416610885512166 3 Q9ULW3,Q8NCM8 2 +Muscle cell proliferation 0.2885337588646604 0.1718871070873776 0.8635262827808765 1.0 0.942770088612451 27 P31749,P09493,P09601,Q9Y2S7,Q8NDZ4 5 +Retinal metabolic process 0.3162570328693996 0.1680801381083329 0.8665202345417078 1.0 0.945177790078585 4 Q8NBN7,Q9BTZ2,Q8TC12 3 +Response to reactive oxygen species 0.2769142938240617 0.1675592173658286 0.866930057320219 1.0 0.9453127782262544 36 P31749,P09493,P09601,P00374,O95831,Q99720 6 +Unsaturated fatty acid biosynthetic process 0.329557284941351 0.167136960046394 0.8672622851070735 1.0 0.9454169270577256 11 O95864,O00767,Q8WXW3,P14174 4 +Muscle contraction 0.2710997545930541 0.1627830035092607 0.8706892909972981 1.0 0.9480042049754768 49 P00813,P16615,P05023,Q96PU5,P09493,P05026,P10253,Q86U42,P60660,P50402,P67936,P0DP25 12 +Synaptic transmission gabaergic 0.3651119881433103 0.1624737528036924 0.8709327958671225 1.0 0.9481131358731366 6 P33176,P51790,Q9BQT9 3 +Vesicle mediated transport in synapse 0.2771367929325805 0.1593017007885188 0.8734311808355988 1.0 0.9500504730320068 38 P16615,Q13277,O95721,P20339,P49841,Q9Y263,Q7L0J3,Q4J6C6,P51790,P0DP25 10 +Import into cell 0.2776539575222972 0.157791761850759 0.8746208904230488 1.0 0.950875055898327 32 P31749,Q99808,P05023,Q15041,P05026,P30825,P31751,P98164,Q9Y289,O75915,P55011,P54709,Q15758,P08195 14 +Cardiac ventricle development 0.3041156714587452 0.15693665561852 0.8752947707778338 1.0 0.9509179166005602 17 O75844 1 +Metencephalon development 0.2754472137116531 0.1568156272445305 0.8753901564708451 1.0 0.9509179166005602 33 P54802,P04062 2 +Interleukin 1 production 0.3433196133468727 0.1557976341519293 0.876192535527681 1.0 0.95101929172318 9 P49755,P05067 2 +Prostanoid biosynthetic process 0.3427788108489661 0.1538079427645142 0.8777611709437914 1.0 0.952347032321718 9 P14174 1 +Positive regulation of amyloid precursor protein catabolic process 0.3618124022799382 0.1521418753247146 0.8790750368910154 1.0 0.9530523160782022 6 P10909 1 +Neutrophil migration 0.3123347139826069 0.151886544099071 0.8792764214101574 1.0 0.953114297047684 15 P35613 1 +Striated muscle adaptation 0.3349928302577971 0.1480389808917521 0.8823120048526383 1.0 0.9558481353462006 5 P16615,Q13555 2 +Regulation of mrna processing 0.2446098164325499 0.1457530404106154 0.8841163482270957 1.0 0.9572616227773388 94 P09012,Q9BWF3,P98179,Q15287,P26368,P61978,Q16629,Q07666,P62995,P22626,O43251,P38159,P50750,Q13595,P98175,Q14011,P31483,Q96E39,Q9UHX1,Q9UNW9,P52756,O75525 22 +Regulation of exocytosis 0.2756490420256695 0.1425076134357178 0.8866790660959896 1.0 0.9594076535409946 41 P16615,O43633,Q00535,Q15019,P09601,P20339,P51151,P61026,O14964,P49841,P11279,Q9P253,Q4J6C6,P51809,P51149,P0DP25 16 +Regulation of microtubule based movement 0.3328544172147085 0.1412947592455854 0.8876370895976571 1.0 0.960129873183456 5 P11279,P78318 2 +Central nervous system neuron development 0.3174761749793881 0.1410532257571809 0.8878278945527402 1.0 0.9601791122727966 13 O14949,Q8N3R9 2 +Polysaccharide biosynthetic process 0.3052335169006357 0.1382490052044479 0.8900436263503737 1.0 0.962260482013679 16 O43505,Q7LGA3,P31751,P22413 4 +Regulation of epidermal growth factor activated receptor activity 0.3368214816746893 0.1323165088271911 0.8947339500268467 1.0 0.9670149919423436 9 Q9BRG1,P78536,P05067 3 +Regulation of mrna catabolic process 0.251957020259151 0.130245190794439 0.8963724419772428 1.0 0.9678486730512476 80 Q14011,P31749,Q969T7,Q92804,P67809,P35637,Q14103,Q13151,P08670,Q15024,Q99729,O60506,Q92945,P98175 14 +Mesoderm morphogenesis 0.3362313038731657 0.1302306061137653 0.8963839805941423 1.0 0.9678486730512476 9 Q5T9L3 1 +Negative regulation of peptidyl tyrosine phosphorylation 0.3203798753626391 0.1295814063624393 0.8968976147728327 1.0 0.9681194903666662 11 Q9BRG1,O95684 2 +Positive regulation of innate immune response 0.2780915819249037 0.1290912096831188 0.8972854774662951 1.0 0.968220385144207 30 Q9NUD5,Q9H1D9,P11279,P23246,Q9BY67,Q15233,Q96PK6 7 +Regulation of protein export from nucleus 0.3074347563749462 0.1284340412481537 0.8978054932051978 1.0 0.9685923122091336 15 Q9Y3B8,Q9C0E2,P62258,P49841,P50402 5 +Cellular component disassembly involved in execution phase of apoptosis 0.3422444553778175 0.1275961775328636 0.8984685562930599 1.0 0.9691494513694848 8 Q07812,O95831,Q9Y2C4 3 +Regulation of action potential 0.3168157358543892 0.1254205072538421 0.9001906538613396 1.0 0.9701595268364894 12 P0DP25,P04062 2 +Extrinsic apoptotic signaling pathway 0.2733834820955138 0.122872991150616 0.9022076734702144 1.0 0.9714967981548628 41 P31749,Q9NR28,P09601,Q07820,O00571,Q9NQX7,P61289,O43464 8 +Protein peptidyl prolyl isomerization 0.28184857854775 0.1212355703081081 0.9035044508659544 1.0 0.9725180644581584 26 Q9NWM8,O95302 2 +Chaperone mediated protein folding 0.2726191874112024 0.1205863356532943 0.9040186924257692 1.0 0.9727239796363352 42 O75718,Q32P28,O14737,P10909,P40855,P48723 6 +Positive regulation of vasculature development 0.2867647803354668 0.1197176302077224 0.9047068339198268 1.0 0.973118641316021 19 P09601,Q86UE4,Q9H2J4 3 +Tricarboxylic acid metabolic process 0.3257045163972165 0.1190103236090439 0.9052671768550946 1.0 0.973464167236466 10 P48735 1 +Negative regulation of protein catabolic process 0.2693744544949045 0.1171017090797294 0.9067794554062016 1.0 0.9747785622706368 46 P10619,Q9UL15,P49069,Q16850,Q9H2J4,Q96HY6 6 +Ear morphogenesis 0.3086807107709237 0.1170953736089052 0.9067844758420148 1.0 0.9747785622706368 14 O75569,O95747,P54802 3 +Positive regulation of protein catabolic process 0.243357202709034 0.1150285961696418 0.9084224560153924 1.0 0.9762230518154328 72 Q9UMX0,Q96PU5,Q13190,P46934,Q96HY6,P51572,Q9BW61,P31749,P25054,P53634,Q96J02,Q8NF37,P04062,Q96JB5,P10909,Q9Y5X1,Q9UII2,P46379,P49841,Q8IXJ6,P51149,P0DMV9,O60826,Q9UBS8 24 +Protein localization to membrane raft 0.2998265619503977 0.1150271154144716 0.9084236296966124 1.0 0.9762230518154328 4 P05026 1 +Cell cycle dna replication 0.2857064057590668 0.1138264509385588 0.9093753700467826 1.0 0.9768531958316626 19 O75844 1 +Positive regulation of response to biotic stimulus 0.2700836081176634 0.1113646978080343 0.9113271529558208 1.0 0.9785477098107264 35 Q9NUD5,P14174 2 +Plasma membrane tubulation 0.3228672985781948 0.1111012767100446 0.9115360363430784 1.0 0.9786130058790456 5 Q9UNF0,Q9Y5X1,Q9Y371,P50570 4 +Cell aging 0.2734880566588107 0.1099290287667993 0.912465660428062 1.0 0.9793560356487496 31 P67809,P14174,O75844,P24941 4 +Leukocyte cell cell adhesion 0.2676585067661416 0.1098548287029021 0.9125245071152972 1.0 0.9793560356487496 47 P00813,P31749,P30825,Q9HCL2,Q08722,Q9NUQ9 6 +Negative regulation of response to biotic stimulus 0.2803893464292443 0.1091036295228892 0.9131202961344264 1.0 0.9798363430999228 23 P04439,P01889,Q8IXJ6,Q86UT6,Q96J02,O43657,Q7Z739 7 +Positive regulation of neuron death 0.2795744971606863 0.1078039020222066 0.9141512475659253 1.0 0.980783375838182 21 Q07820,P49841,Q15375,P10909,Q07812,O95831 6 +Regulation of polysaccharide metabolic process 0.335774267161859 0.1066396619224745 0.915074852310517 1.0 0.9814556473418056 8 P22413,P31751 2 +Cellular response to calcium ion 0.3114875664118859 0.1038407573269004 0.9172957216164104 1.0 0.983521638108461 12 Q92542,O75131,Q6NUK1,Q99538,Q86YQ8 5 +Protein localization to synapse 0.305630961449757 0.1036879787618283 0.9174169667883908 1.0 0.983521638108461 14 Q13277,Q9UQB8,Q9BQT9 3 +Response to light stimulus 0.255530962134693 0.1031876332119579 0.9178140547836467 1.0 0.983702762266766 59 P31749,Q14011,Q15555,Q9BWF3,P27544,P22830,P46934,P31751,P05067,Q96K76,Q8NBN7,Q07812,Q9BV73 13 +Regulation of lipid kinase activity 0.3451334257287293 0.1030614530814633 0.917914198047987 1.0 0.983702762266766 6 Q05639 1 +Regulation of hemopoiesis 0.2668349743300924 0.1023082799727772 0.918511983328302 1.0 0.9841838031479812 47 P00813,O43251,Q9GZS3,O96005 4 +Response to lipid 0.2445438418837743 0.1016427828867476 0.9190402194499304 1.0 0.9842710760564884 159 P07196,Q05086,P05023,O15173,P46934,Q96HY6,O75874,P16278,O15118,P31749,O43251,P16435,Q13151,Q86UE4,P14174,P0DP25,P50416,P04062,Q13126,P08670,P10909,O95831,O43464,Q8WTV0,Q14103,P16220,P30536,O95747,Q9UBS8 29 +Negative regulation of protein tyrosine kinase activity 0.3394872177373336 0.1008820458107763 0.91964409575577 1.0 0.9847582353936948 7 O95684 1 +Actin mediated cell contraction 0.2883726961347954 0.1002599679038005 0.9201379382876284 1.0 0.9851274314179388 18 Q9UM22,P16615,P05023,Q96PU5,P09493 5 +Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.3437936193786255 0.0993539208017161 0.9208572675474014 1.0 0.985737881636018 6 O43464,Q07812 2 +Regulation of protein catabolic process 0.2432608231005045 0.0941409151033012 0.9249972191314976 1.0 0.9898488700194412 135 P10619,Q05086,Q9UMX0,P49069,Q96PU5,Q13190,P46934,Q16850,Q96HY6,Q9H2J4,P61289,P51572,Q9BW61,P31749,Q9UL15,Q9Y297,P04062,Q9UL46,P24941,P10909,P46379,Q05639,Q9UBS8 23 +Regulation of dephosphorylation 0.2679609963525742 0.0937842187385339 0.9252805680486827 1.0 0.9899917879607812 36 O43768,O75116,P78318,P62942,P04062,O95429,P62258,P49841,Q96JB5,Q86XL3,P0DP25 11 +Dsrna processing 0.281984548009855 0.0934329405125933 0.9255596222227171 1.0 0.99013006527516 19 P22626,Q9UGR2,O00571,O75844,O75569 5 +Positive regulation of epithelial cell migration 0.2675076212276496 0.0920834041725239 0.9266317739770544 1.0 0.990956212656044 34 P31749,Q15555,P09601,Q99538,Q9NQC3,P78536,P06576,Q8WTV0 8 +Positive regulation of neuron projection development 0.2690189981301177 0.0908964492732027 0.9275748715840536 1.0 0.9918042915869616 32 O15031,Q14108,Q9NZQ3 3 +Protein containing complex localization 0.2644862085406688 0.0898190991399222 0.9284309706156524 1.0 0.9925590884501532 48 P33176,Q13277,Q7Z4L5,Q96D46,Q9BTX1,O15400,P57105,P23246,Q8NCM8,O43805,Q86U38,Q14168 12 +Dendritic transport 0.340028494129874 0.0891272958565924 0.9289807447579936 1.0 0.9928256374685608 6 P33176,P23246 2 +Oogenesis 0.3021351651927948 0.088662345550541 0.92935025853492 1.0 0.9930599609793512 14 Q8N2A8,Q9Y2W6,Q8IXJ6,Q9H6S0 4 +Response to bacterium 0.2511461238257916 0.0884359411339289 0.9295301962968396 1.0 0.9930916694674772 63 Q9UQB8,P31749,Q8WTV0,P04439,P01889,Q13151,P08670,P30536,Q9BTY2,Q8IXJ6,Q9NUQ9,Q86UE4,Q9NZ08,P14174 14 +Cell killing 0.2750918636478188 0.0854006987135819 0.9319428377005584 1.0 0.9955083585522856 20 O15400,P53634,P04439,P01889,P11279,Q9NUQ9 6 +Regulation of transcription regulatory region dna binding 0.3086445607493542 0.0847492766302856 0.9324607197676285 1.0 0.9957110733904772 11 O75844 1 +Ventral spinal cord development 0.2893100384956979 0.0845896507223634 0.9325876271045288 1.0 0.9957110733904772 4 Q14203,Q9ULW3,Q8NCM8 3 +Positive regulation of chemotaxis 0.2760799405576356 0.0845363189549604 0.9326300278253664 1.0 0.9957110733904772 22 Q13277,Q8NE86,Q99538,Q4KMQ2,Q13641,O95747,P78536,P27361 8 +Regulation of chromatin organization 0.2803059810167444 0.0844039734556008 0.9327352482010054 1.0 0.9957110733904772 19 Q9UK61,Q8NEY8 2 +Regulation of innate immune response 0.262801958374516 0.0840601965189877 0.9330085711685796 1.0 0.9958419972308048 49 P04439,P01889,Q9H1D9,Q16543,Q9NUD5,P11279,P23246,Q9BY67,P18031,Q7Z739,Q15233,Q96PK6,Q9NZ08 13 +Thyroid gland development 0.2616250586740118 0.0838251445036975 0.9331954559510448 1.0 0.9958806343259254 3 P27361 1 +Organic hydroxy compound catabolic process 0.2997903978391512 0.0787937350531613 0.9371966872590424 1.0 0.9999891679197628 14 Q10713,Q8WTV0 2 +Regulation of protein dephosphorylation 0.2726981980186098 0.0766922465869533 0.9388683727027878 1.0 1.0 29 O75116,P04062,P62258,O43768,Q86XL3,P0DP25 6 +Embryo implantation 0.313505359297329 0.0761011342976968 0.9393386377207648 1.0 1.0 10 P35613,Q13263 2 +Negative regulation of signaling receptor activity 0.3349553965588003 0.0758013291504272 0.939577158660323 1.0 1.0 6 Q9BRG1,Q9UNH7,P30533 3 +Appendage development 0.2834716346980187 0.0751849216643433 0.9400675811649126 1.0 1.0 18 Q9NX62,P42892,Q07812,O95747,O75569 5 +Organelle inheritance 0.3194230406030167 0.0742394389391927 0.9408198646838112 1.0 1.0 9 Q13190,P06493 2 +Response to retinoic acid 0.2875853764178956 0.0733866662752011 0.941498427755391 1.0 1.0 17 O43464,O95747,P49841,P16220 4 +Meiotic chromosome segregation 0.2741645828411778 0.0732744264319379 0.941587741733166 1.0 1.0 22 Q9BTX1,P46379,Q92791,Q9BZD4 4 +Head development 0.2435646444488038 0.0678421495614959 0.9459112905358292 1.0 1.0 169 P07196,P50897,Q05086,O95456,Q15058,Q15375,P35610,O15027,Q8NCM8,O15031,P62995,Q7Z4L5,Q5T9L3,O43251,P05067,Q16352,O75569,Q8TAB3,P54802,P0DP25,P04062,P62258,P24539,Q8N3R9,Q07812,Q9NQC3,O75503,Q96QD8,O43464,O14949,O94901,Q9UQB8,P61421,O95470,P46379,Q92542,O75489,Q96N66,P49841,P16220,Q14103,Q8IXJ6,Q9BY67,P07942,P27361 45 +Regulation of perk mediated unfolded protein response 0.2828179369324841 0.0672216999319762 0.9464052101477614 1.0 1.0 4 P57088 1 +Renal water homeostasis 0.2554766133806917 0.0668565852287698 0.9466958756351492 1.0 1.0 3 P17612,O76024 2 +Regulation of calcium ion transmembrane transport 0.2733789466873095 0.0650227365020997 0.9481558974482708 1.0 1.0 24 Q9UMX0,P05026,P21796,Q07812,P0DP25 5 +Chromosome organization involved in meiotic cell cycle 0.281417161175546 0.0649358764422999 0.9482250555911188 1.0 1.0 18 Q9BTX1,P46379,Q92791 3 +Bergmann glial cell differentiation 0.330581245949765 0.0647341796694479 0.9483856484443872 1.0 1.0 6 P08670,Q7Z4L5 2 +Negative regulation of endoplasmic reticulum unfolded protein response 0.3260862843266047 0.0634201816632451 0.9494319169559132 1.0 1.0 7 Q96HY6,P18031 2 +Inositol phosphate mediated signaling 0.3260225251926515 0.0632512638613941 0.9495664238098398 1.0 1.0 7 Q08209,Q8IWX8,Q99653,P49841,P42345,Q9UHD1 6 +Calcineurin mediated signaling 0.3260225251926515 0.0632512638613941 0.9495664238098398 1.0 1.0 7 Q08209,Q8IWX8,Q99653,P49841,P42345,Q9UHD1 6 +Negative regulation of ryanodine sensitive calcium release channel activity 0.3050947867298462 0.0628874288608505 0.94985614534564 1.0 1.0 5 P0DP25,P78417,P30626,P62942 4 +Positive regulation of sequestering of calcium ion 0.3050947867298462 0.0628874288608505 0.94985614534564 1.0 1.0 5 P0DP25,P78417,P30626,P62942 4 +Negative regulation of calcium ion transport into cytosol 0.3050947867298462 0.0628874288608505 0.94985614534564 1.0 1.0 5 P0DP25,P78417,P30626,P62942 4 +Astrocyte differentiation 0.2983487114263015 0.0620264753077339 0.9505417483427956 1.0 1.0 13 P05067 1 +Positive regulation of cell population proliferation 0.2407233426571488 0.0599182063051928 0.9522207794120175 1.0 1.0 140 P00813,Q13277,Q9GZP9,Q99584,Q15058,Q9BSK2,Q96HY6,Q9H2J4,P43490,P43307,P31749,P04439,P09601,Q99538,P14174,P31751,Q9HCL2,P24941,Q08722,Q9NQC3,Q01085,P55209,P30825,P30536,O95747,P78536,O95684 27 +Axon development 0.249954465681869 0.056123987581035 0.9552430347265236 1.0 1.0 85 P07196,P16949,O00264,P35613,P00374,P42892,P05067,P30536,Q96G23,Q9NQC3,O15031,Q9UNW9,P10586,Q9UQB8 14 +Cellular response to potassium ion 0.2777454208623373 0.054417979927326 0.9566021541686722 1.0 1.0 4 Q14168 1 +Response to potassium ion 0.2777454208623372 0.0544179799273255 0.9566021541686728 1.0 1.0 4 Q14168 1 +Dendrite extension 0.3015006318686655 0.0540213048942538 0.95691819017305 1.0 1.0 5 Q96PU5 1 +Regulation of calcineurin mediated signaling 0.3259259259259287 0.0533903454581066 0.9574208974510596 1.0 1.0 6 Q8IWX8,Q99653,P49841,P42345,Q9UHD1 5 +Regulation of dna binding transcription factor activity 0.2429798366763478 0.0513097209540366 0.9590787221082028 1.0 1.0 68 P31749,P09601,P05067,Q92905,Q9Y297,P10909,Q96HY6,P22413,O75381 9 +Nucleoside metabolic process 0.2738556091385861 0.0507223663491075 0.9595467538177578 1.0 1.0 19 P00813 1 +Mammary gland morphogenesis 0.3246258868390737 0.0503030589618071 0.9598808861588036 1.0 1.0 6 Q9Y297,Q07812 2 +Negative regulation of erbb signaling pathway 0.2987340713993173 0.0498606088217732 0.9602334678432684 1.0 1.0 11 Q9BRG1,Q99538,P00533,Q9UNH7,Q9Y5X3,P51149 6 +Cellular response to light stimulus 0.268365752723413 0.0467872511530633 0.9626827900126288 1.0 1.0 29 Q15555,P27544,P46934,P31751,Q96K76 5 +Regulation of synaptic transmission glutamatergic 0.2742078768137339 0.0458889434794365 0.9633987667199512 1.0 1.0 4 P19022,Q00535,Q8NBU5 3 +Negative regulation of rig i signaling pathway 0.2739117559964381 0.0451899355414207 0.9639559163308852 1.0 1.0 4 Q92890,Q07021,Q86UT6 3 +Animal organ morphogenesis 0.2374036342828313 0.0434927629420317 0.9653087334046336 1.0 1.0 107 O95470,Q15555,Q9NX62,P16435,P04062,P09493,P35613,Q9Y297,Q15363,P10253,Q92896,P53701,Q9NQC3,O75844,P54802 15 +Endocrine system development 0.288066427487813 0.0429901490385263 0.9657093865236084 1.0 1.0 15 P31749,Q15382,P49841,P16220,P30536 5 +Regulation of jnk cascade 0.2908535563274861 0.0427767896246748 0.9658794662459598 1.0 1.0 14 P05067 1 +Sulfur compound catabolic process 0.3080271559397544 0.0402013824111591 0.9679325755179148 1.0 1.0 9 P15586 1 +Regulation of cytoplasmic translation 0.2837684417364619 0.0386472609381803 0.9691716216374362 1.0 1.0 16 P67809,O60506 2 +Membrane depolarization 0.3017649426888511 0.0384902678430008 0.9692967908717522 1.0 1.0 10 P30536,Q9UII2,Q96PU5 3 +Positive regulation of insulin secretion involved in cellular response to glucose stimulus 0.2706544270062115 0.0376532238574155 0.9699641714797628 1.0 1.0 4 O95563,P22059,P30626 3 +Cellular response to steroid hormone stimulus 0.2496600273109927 0.0362350626028334 0.9710949284235084 1.0 1.0 58 O15118,Q05086,O43251,O15173,P46934,Q96HY6,O95831,Q9UBS8 8 +Cell differentiation involved in metanephros development 0.2695351628255756 0.0351279705523421 0.971977697895944 1.0 1.0 4 O95747 1 +Metanephric nephron development 0.2695351628255756 0.0351279705523421 0.971977697895944 1.0 1.0 4 O95747 1 +Hepatocyte growth factor receptor signaling pathway 0.3135421285615629 0.0319228549044769 0.9745335723481512 1.0 1.0 7 P16949,Q8IXJ6 2 +Negative regulation of protein binding 0.2675681430083505 0.0286839908789664 0.977116624542704 1.0 1.0 26 P31749,P16615,P49841,P35269,Q07812,O75381,P10586,P27361 8 +Positive regulation of cellular protein catabolic process 0.2528864068138173 0.0249950932905064 0.9800588773742708 1.0 1.0 52 P31749,P46379,Q9UMX0,P53634,P04062,P49841,P10909,Q8IXJ6,Q96HY6,P51572,Q9UII2,Q9UBS8,Q9BW61 13 +Proteasome mediated ubiquitin dependent protein catabolic process 0.2390228031753966 0.0249911868743757 0.9800619932700544 1.0 1.0 138 Q9UBV2,Q9GZP9,Q9UMX0,P49069,Q96PU5,P30260,P46934,Q96HY6,P51572,P31749,Q9UL15,Q9Y297,Q9BUN8,P04062,P33908,P24941,P10909,Q9UJX3,Q96A33,P46379,Q9UBS8 21 +Activation of immune response 0.2552111102874167 0.0245630807424871 0.9804034677077134 1.0 1.0 50 P00813,Q99623,P46379,P04439,Q9NUD5,P10909,Q08722,Q07812,P23246,Q15233,Q96PK6,Q07666 12 +Positive regulation of non motile cilium assembly 0.3127972475229778 0.023841067139537 0.9809793825087116 1.0 1.0 6 Q15555,Q9P2S5 2 +Response to hydrogen peroxide 0.2666367952546012 0.022956610193199 0.9816848838684722 1.0 1.0 26 P09601 1 +Skin epidermis development 0.2850301375092107 0.0207157990650396 0.983472365893178 1.0 1.0 14 Q08J23,P35222,P00533,Q9Y251,O75844 5 +Regulation of exit from mitosis 0.3085358624777736 0.0203358969497301 0.9837754200771078 1.0 1.0 7 Q96SB3,Q99623,Q96FF9,Q8IXJ6,Q9NQW6,O43264 6 +Negative regulation of protein metabolic process 0.2425997010203281 0.0187808130544447 0.9850159600888212 1.0 1.0 301 P10619,Q9BRG1,P49069,P07858,Q01105,Q15024,Q16850,Q96HY6,O00571,Q9NQX7,Q9H2J4,O43768,Q9BPZ3,P31749,Q9UL15,Q969T7,O75718,P78318,Q96KC8,P16435,Q15041,O95197,P05067,Q96K76,O15212,Q9BXS4,O60506,Q92945,Q9UHV9,P14174,Q9Y287,P0DP25,Q9Y6M1,Q32P28,P04062,O75298,P10909,Q15363,O14734,Q92896,Q8WXW3,Q9NQC3,Q16625,Q15392,Q14011,P49755,P46379,P31483,Q9Y3B8,Q13501,P67809,P00374,Q14103,P30536,Q10713,P22413,O95684 57 +Actomyosin contractile ring organization 0.2855450236966717 0.0183159600777428 0.985386795301586 1.0 1.0 5 Q8WUM4,Q15149,Q9NQW6,Q9H0H5 4 +Regulation of erbb signaling pathway 0.2786720358739505 0.0173434578496246 0.9861626164581798 1.0 1.0 16 Q9BRG1,Q99538,Q9UNH7,Q9Y5X3,P78536,P51149,Q9NQC3 7 +Regulation of protein tyrosine kinase activity 0.2781931871710509 0.0153909518967637 0.9877202819135624 1.0 1.0 16 Q9BRG1,P05067,P78536,P18031,O95684 5 +Histone h4 deacetylation 0.2596979567663552 0.014346917980234 0.9885532083397384 1.0 1.0 4 Q8IXJ6,Q92769,Q13547 3 +Regulation of dna binding 0.2650249252567254 0.0131400252239636 0.9895160784388828 1.0 1.0 26 P09601,O75844 2 +Positive regulation of oligodendrocyte differentiation 0.2828791469194267 0.0129323602437184 0.989681757041641 1.0 1.0 5 Q92769,Q15382,P42345,Q13547 4 +Regulation of signal transduction by p53 class mediator 0.2577092156420372 0.0127794231781144 0.9898037730814888 1.0 1.0 37 P31749,Q8N2F6,P61978,O75844,P14174 5 +Posttranslational protein targeting to endoplasmic reticulum membrane 0.2971229471150547 0.0107342025787981 0.9914355099613515 1.0 1.0 9 P46379,Q99442 2 +Negative regulation of epithelial cell differentiation 0.2815169810156985 0.0102455855803961 0.9918253484675535 1.0 1.0 5 O95747 1 +Protein localization to chromatin 0.2697096897648075 0.0096500852845965 0.9923004654432716 1.0 1.0 18 Q9UK61 1 +Regulation of muscle system process 0.25707934599515 0.0090695195046767 0.9927636696189412 1.0 1.0 36 O75116,P00813,P16615,P05023,P09493,P05026,P0DP25 7 +Regulation of ryanodine sensitive calcium release channel activity 0.3051851851851882 0.0083692064342813 0.9933224173536788 1.0 1.0 6 P17612,P62942,P78417,P30626,P0DP25 5 +Release of sequestered calcium ion into cytosol by endoplasmic reticulum 0.305185185185188 0.0083692064342807 0.9933224173536792 1.0 1.0 6 P17612,P78417,P30626,Q9NVV0,P0DP25 5 +Positive regulation of metaphase anaphase transition of cell cycle 0.3027040592475434 0.0075505541338153 0.9939755866740154 1.0 1.0 7 Q9UJX3 1 +Telencephalon development 0.2575770150656505 0.0073846910607998 0.9941079225690974 1.0 1.0 45 P07196,P62995,Q15058,Q96N66,P62258,P49841,Q8N3R9,Q07812,Q9NQC3,Q96QD8,O14949,O94901 12 +Regulation of hormone secretion 0.2591582486380727 0.0068678759556339 0.9945202708872458 1.0 1.0 31 O43768,P50416,P53985,Q8N183,Q8NE86,P16220,Q9UNH7,P51809,Q8N5M9,Q9BRT2 10 +Dna catabolic process 0.2991771077305798 0.0061977115828094 0.9950549732735428 1.0 1.0 8 Q07812,O95831 2 +Negative regulation of epidermal growth factor activated receptor activity 0.2783655093611908 0.0041949938629633 0.9966528889811436 1.0 1.0 5 Q9BRG1,Q9UNH7 2 +Regulation of protein stability 0.2362999525706464 0.0030608608170524 0.9975577902247652 1.0 1.0 113 P10619,Q9UBV2,Q99623,P49069,Q96PU5,O95429,P05026,Q16543,Q86Y82,Q96HY6,Q9H2J4,P40855,O15027,Q9UL15,O75718,Q96K76,Q9BUN8,P11279,Q9Y297,O75569,Q32P28,P10909,Q9NQC3,O76024,P13473,P46379,P16220 27 +Regulation of coagulation 0.2774833816563395 0.0025426314400906 0.9979712758160816 1.0 1.0 5 Q4KMQ2,Q9Y251 2 +Regulation of circadian rhythm 0.261708570550505 0.002532585374027 0.9979792913912826 1.0 1.0 29 O75116,Q05086,Q9BWF3,P49841,Q14103,Q9Y297,P23246,P06493,Q15233 9 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.3016296296296324 0.0015595707419787 0.9987556430879287 1.0 1.0 6 P25054,O94992,O00410,O95373,O00255 5 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..55be1547639cd456a875c6b18f510f9499960987 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of janus kinase activity", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in coronary vascular morphogenesis", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular valve development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Bile acid signaling pathway", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in prostate gland morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine secretion", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system myelin maintenance", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondroblast differentiation", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Convergent extension involved in gastrulation", "Convergent extension involved in organogenesis", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Corticotropin secretion", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial nerve morphogenesis", "Cranial nerve structural organization", "Cranial skeletal system development", "Craniofacial suture morphogenesis", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide biosynthetic process", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna cytosine deamination", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine secretion", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal cell differentiation", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eyelid development in camera type eye", "Face development", "Facial nerve morphogenesis", "Facial nerve structural organization", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated inhibitory signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain dorsal ventral pattern formation", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain neuron fate commitment", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactolipid biosynthetic process", "Galactolipid metabolic process", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Hard palate development", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Heat generation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindgut development", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus cell migration", "Hypothalamus development", "Hypothalamus gonadotrophin releasing hormone neuron differentiation", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immune complex clearance", "Immune effector process", "Immune response", "Immune response inhibiting cell surface receptor signaling pathway", "Immune response inhibiting signal transduction", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Induction of positive chemotaxis", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Inhibitory postsynaptic potential", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 mediated signaling pathway", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Iodide transport", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung growth", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage fusion", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of animal organ identity", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Mast cell proliferation", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane fusion involved in viral entry into host cell", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte activation", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Motor neuron migration", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multinuclear osteoclast differentiation", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myoblast proliferation", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immune response to tumor cell", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of atpase coupled calcium transmembrane transporter activity", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axon extension involved in axon guidance", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of behavior", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cardiocyte differentiation", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of catecholamine secretion", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of ceramide biosynthetic process", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of dopamine secretion", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of feeding behavior", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell activation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of pathway restricted smad protein phosphorylation", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of smad protein signal transduction", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sphingolipid biosynthetic process", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor 2 signaling pathway", "Negative regulation of toll like receptor 4 signaling pathway", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest cell migration involved in autonomic nervous system development", "Neural crest formation", "Neural fold formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal signal transduction", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast development", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Osteoclast fusion", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parasympathetic nervous system development", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Peristalsis", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phasic smooth muscle contraction", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyamine transport", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axon extension involved in axon guidance", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion mediated by integrin", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermal growth factor activated receptor activity", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of granulocyte differentiation", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of heat generation", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of inhibitory postsynaptic potential", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myoblast proliferation", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immune response to tumor cell", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide mediated signal transduction", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of osteoclast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of peroxisome proliferator activated receptor signaling pathway", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phospholipid translocation", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein localization to synapse", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of skeletal muscle tissue growth", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of uterine smooth muscle contraction", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Proline transport", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prostate gland morphogenesis", "Prostate glandular acinus development", "Prostate glandular acinus morphogenesis", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to non motile cilium", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine biosynthetic process", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside catabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Receptor transactivation", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of bile acid secretion", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching involved in prostate gland morphogenesis", "Regulation of branching involved in ureteric bud morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardiac muscle tissue development", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cdc42 protein signal transduction", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of corticotropin secretion", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of eating behavior", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endosome to plasma membrane protein transport", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of heat generation", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage fusion", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myoblast proliferation", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immune response to tumor cell", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of positive chemotaxis", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rab protein signal transduction", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sensory perception", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle cell proliferation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of skeletal muscle tissue growth", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snare complex assembly", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle cycle", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type b pancreatic cell proliferation", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of voltage gated sodium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cycloheximide", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoprotein", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 18", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to luteinizing hormone", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cell programmed cell death", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal complex assembly", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue growth", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Tolerance induction to self antigen", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Trigeminal ganglion development", "Trigeminal nerve development", "Trigeminal nerve morphogenesis", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent glycoprotein erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urea cycle", "Urea metabolic process", "Ureter development", "Ureter morphogenesis", "Ureteric bud elongation", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Vestibulocochlear nerve development", "Vestibulocochlear nerve morphogenesis", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APOBEC3C", "APOL2", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRIX1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C19orf70", "C1D", "C1QBP", "C2CD2L", "C2CD5", "C3orf58", "C5orf51", "C8orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCDC8", "CCDC93", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP135", "CEP250", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM129B", "FAM162A", "FAM208A", "FAM210B", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN3", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1468", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRRFIP2", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYN", "LYPLA1", "LZTFL1", "LZTS2", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METAP1", "METTL13", "METTL15", "MFAP1", "MFF", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MMS22L", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL47", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCK1", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RILPL1", "RINT1", "RIOX1", "RIOX2", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SATB2", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STAT1", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC4", "TTC5", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA5", "UBA6", "UBAC1", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBLCP1", "UBN2", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "UROD", "USE1", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS52", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WNK1", "WNK3", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["ABAT", "ABCB1", "ABCD3", "ABHD10", "ABHD12", "ABT1", "ACADVL", "ACAT2", "ACBD3", "ACBD5", "ACOT8", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL6", "ACTN4", "ADA", "ADAM17", "ADAM9", "ADD1", "ADI1", "ADPGK", "AFG3L2", "AGPS", "AHCYL1", "AHSA1", "AIFM1", "AIP", "AK1", "AK2", "AK4", "AKAP9", "AKT1", "AKT2", "ALDH3A2", "ALG1", "ALG11", "ALYREF", "ANAPC7", "ANK3", "ANKLE2", "ANLN", "ANO6", "ANXA11", "ANXA6", "ANXA7", "APC", "APLP2", "APOL2", "APOOL", "APP", "ARF4", "ARFGAP1", "ARFIP2", "ARL1", "ARL6IP1", "ARL6IP5", "ARMC1", "ARMC10", "ARVCF", "ASAH1", "ASNA1", "ATAD1", "ATAD3A", "ATAD3B", "ATG4B", "ATG9A", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATPAF2", "ATPIF1", "AURKB", "B4GAT1", "BABAM2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BASP1", "BAX", "BCAP31", "BCL2L13", "BICD2", "BNIP1", "BRD7", "BSG", "BTRC", "C12orf43", "C12orf73", "C19orf70", "C1QBP", "C3orf58", "CADM1", "CALM3", "CALR", "CAMK1", "CAMK2G", "CAMLG", "CANT1", "CANX", "CARM1", "CCAR2", "CCDC22", "CCDC47", "CCDC93", "CCNA2", "CCNB2", "CD47", "CDC27", "CDC37", "CDC42", "CDCA5", "CDH2", "CDK1", "CDK2", "CDK5", "CDK5RAP3", "CDK9", "CDS2", "CEP135", "CEP250", "CERS1", "CERS2", "CETN2", "CFDP1", "CHCHD3", "CHERP", "CHKA", "CHMP2A", "CHORDC1", "CHP1", "CHST14", "CIRBP", "CISD1", "CLCC1", "CLCN3", "CLCN7", "CLN5", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLSTN3", "CLTA", "CLU", "CLUH", "CNNM3", "CNNM4", "COA3", "COMT", "COPS3", "COPS4", "COPS5", "COPS8", "COQ8A", "COQ9", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE3", "CPNE8", "CPOX", "CPSF6", "CPT1A", "CPT2", "CPVL", "CREB1", "CRTAP", "CSK", "CTCF", "CTNNB1", "CTSA", "CTSB", "CTSC", "CUTA", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTPP1", "DDA1", "DDRGK1", "DDX17", "DDX39B", "DDX3X", "DDX5", "DENND4C", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHX36", "DHX8", "DIABLO", "DLD", "DNAJA2", "DNAJC1", "DNAJC10", "DNAJC3", "DNM1L", "DNM2", "DOHH", "DOLPP1", "DPM1", "DSC3", "DUSP12", "DVL2", "DYM", "DYNC2H1", "EBP", "ECE1", "ECH1", "EEF1A2", "EEF1E1", "EGFR", "EHD1", "EHD4", "EI24", "EIF2B2", "EIF2D", "EIF2S1", "EIF3E", "EIF4E", "ELMOD2", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "ENPP1", "ENSA", "EPDR1", "EPHA7", "EPHX1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERGIC1", "ERGIC3", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESYT1", "ESYT2", "ETNK1", "EXOC4", "EXOG", "EXOSC2", "EXOSC7", "EYA4", "EZR", "FADS2", "FAM162A", "FAM208A", "FAM210B", "FAM3C", "FAM49B", "FAM8A1", "FANCD2", "FECH", "FGFR1OP", "FHL1", "FKBP14", "FKBP1A", "FKBP7", "FKBP9", "FKRP", "FMR1", "FOXRED1", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "G3BP2", "GAA", "GALNT1", "GALNT2", "GAPVD1", "GBA", "GDAP1", "GGCX", "GHITM", "GINS4", "GLA", "GLB1", "GLG1", "GLUD1", "GM2A", "GNPAT", "GNS", "GOLGA2", "GOLGA4", "GOLGA5", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GOSR1", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPHN", "GPR107", "GPR108", "GPR89B", "GSK3B", "GSS", "GSTO1", "GTF2F1", "GTF3C5", "GUSB", "GYG1", "HACD3", "HCCS", "HDAC1", "HDAC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMCES", "HMGB1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HOOK2", "HPS6", "HPSE", "HS2ST1", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA1B", "HSPA2", "HSPA8", "HTRA2", "ICMT", "IDH1", "IDH2", "IGBP1", "IGF2BP1", "IGF2BP2", "IKBIP", "ILK", "ILVBL", "IMPAD1", "INA", "IPO5", "IPO7", "IQGAP1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "JAGN1", "KDELR1", "KDELR3", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF14", "KIF5B", "KIFBP", "KLC1", "KLC2", "KPNA2", "KPNA6", "L2HGDH", "LACTB", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR3", "LARS", "LBR", "LDAH", "LEMD3", "LETM1", "LGMN", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRPAP1", "LYN", "MACF1", "MAD2L1", "MAGT1", "MAN1A1", "MAN1A2", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MAVS", "MBD1", "MBOAT7", "MCCC2", "MCL1", "MCM2", "MCM4", "MCM6", "MCU", "MCUB", "MED1", "MED25", "MEN1", "MESD", "MFF", "MFN1", "MGEA5", "MGST2", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MOSPD2", "MOV10", "MPC2", "MPP1", "MPP2", "MPP5", "MPV17L2", "MRC2", "MRE11", "MSH2", "MSMO1", "MTAP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTOR", "MTX1", "MTX3", "MYG1", "MYH14", "MYL6", "NAA10", "NAA40", "NAA50", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NCBP3", "NCKIPSD", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFA4", "NDUFA6", "NDUFA8", "NDUFAF2", "NDUFB1", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS2", "NDUFS3", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NELFE", "NENF", "NISCH", "NLN", "NLRX1", "NMD3", "NME3", "NNT", "NOA1", "NONO", "NOP9", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NRDC", "NRP1", "NSD2", "NSUN2", "NSUN5", "NT5C3A", "NT5C3B", "NTMT1", "NUCB2", "NUCKS1", "NUDT12", "NUF2", "NUP37", "NUP62", "NUP93", "NUPL2", "OCIAD1", "OCLN", "OPA1", "OPA3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PACSIN2", "PAIP2", "PCBD1", "PCDH19", "PCID2", "PCM1", "PCYOX1", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE4DIP", "PDE6D", "PEX14", "PEX16", "PEX19", "PFDN2", "PFDN6", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHGDH", "PIBF1", "PIGL", "PIH1D1", "PIP4K2C", "PISD", "PITRM1", "PLAA", "PLBD2", "PLD3", "PLD6", "PLEC", "PLOD3", "PLXNB2", "PMPCA", "PNPLA6", "POFUT2", "POLDIP2", "POLR3F", "PON2", "POR", "PPAT", "PPHLN1", "PPP1R12A", "PPP1R9B", "PPP2R1A", "PPP3CA", "PPT1", "PPT2", "PRAF2", "PRCP", "PREPL", "PRKAA1", "PRKACA", "PRKAG1", "PRKRA", "PRMT1", "PSAP", "PSMB5", "PSMB6", "PSMC3", "PSMD11", "PSMD3", "PSME2", "PSME3", "PSMG1", "PSPC1", "PTDSS1", "PTDSS2", "PTK7", "PTPA", "PTPN1", "PTPN23", "PTPRF", "PUF60", "PXMP2", "QSOX2", "RAB10", "RAB11B", "RAB14", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RACGAP1", "RALY", "RAN", "RBFOX2", "RBM10", "RBM14", "RBM3", "RBM4", "RBM5", "RBMX", "RBMXL1", "RDH11", "RDH13", "RDX", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "RFT1", "RHEB", "RHOA", "RIDA", "RIOX1", "RMDN1", "RMDN3", "RNASET2", "RNF14", "RNF20", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RPL22", "RPL26", "RPN1", "RTN2", "RTN3", "RTN4", "S100A13", "SAMM50", "SAR1A", "SAR1B", "SC5D", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCO1", "SCP2", "SCPEP1", "SDCBP", "SDCCAG3", "SDHB", "SEC11A", "SEC16A", "SEC62", "SEC63", "SEL1L", "SEPT2", "SERAC1", "SET", "SF3B5", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GLB1", "SHTN1", "SIGMAR1", "SIRT2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A6", "SLC29A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLIT2", "SNAP29", "SNRPA", "SNW1", "SNX12", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", 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0.0005428611587646 0.0001128728628543 1.8595792007616816e-05 1.6664565360993773e-13 +Coated vesicle 28 94 3.8787361261151343 0.0001050005758591 21.15776699029126 89.28398058252426 0.7996411773181966 0.4463095457932411 7.252509633536616 8.542551157088123 1.3406722753228342 0.3892656029628454 0.0092811128664131 0.015556573880322 0.0007326498275811 0.0238298072319958 0.0001149034626724 +Mitochondrial protein containing complex 69 164 3.838640192221175 0.000123717569515 45.62621359223301 153.59708737864077 0.8032126729603613 0.4024101172023991 21.080430630469312 12.423857071229754 2.191669513941161 0.4117346592056412 4.799987847751493e-11 2.795486742861714e-07 1.006732554957401e-06 2.231638907907269e-09 5.023352194971536e-13 +Intrinsic component of mitochondrial inner membrane 16 34 3.8378716073996832 0.0001241053389866 13.946601941747574 31.446601941747577 1.7062420859184484 0.2149692261988765 6.992163651608136 3.3601842163433866 1.8185871159494191 0.3070405082296492 2.5077861448413723e-08 9.216009865795702e-05 8.093823153610318e-06 2.5288361102868394e-06 8.084672558338859e-11 +Azurophil granule 31 75 3.781197905560321 0.000156075535538 20.46359223300971 67.00485436893204 0.4795255752980384 0.3097891700346699 6.177875864944045 5.290582926033595 2.1760997104513735 0.3628132485163926 4.243006412370456e-07 0.1054077938723316 0.1010318943027543 3.7577030372156096e-06 9.91092451007827e-10 +Vacuolar membrane 47 138 3.7624876567967886 0.0001682316136355 31.91504854368932 121.20631067961163 0.8693310080509177 0.3422944242486927 10.598363436017626 13.850227259030053 1.9844114292962869 0.3837860427998523 5.0722291341044285e-06 0.2197409699613102 9.746636894093462e-05 2.116619821521985e-05 3.776194238590656e-07 +Endoplasmic reticulum golgi intermediate compartment 21 53 3.753665519877465 0.0001742673676257 14.888349514563108 49.49271844660194 1.4759277407874345 0.3201471070907981 6.47003250199477 5.053350843348441 1.420924643396655 0.3585240832471577 0.0105701462748901 0.0012207780133923 4.4183006803413126e-05 0.0094008643755842 1.936121689685458e-07 +Endoplasmic reticulum golgi intermediate compartment membrane 17 27 3.713128839739844 0.0002047126039901 10.49271844660194 25.839805825242717 1.5441023898993702 0.2324243418613106 5.505729177420246 3.7718384126099376 1.49831312620529 0.2965572765953523 0.0066289890252152 0.0022960708364777 0.0001846581304315 0.0102355224712358 3.217786276624955e-08 +Intrinsic component of plasma membrane 46 89 3.711012396833968 0.0002064319929619 29.711165048543688 79.49271844660194 0.9914207279546418 0.2992612012372248 13.467745416506318 12.62980929789956 2.1277799030157807 0.3627370007757806 0.3662792180696197 0.3907756265990433 0.6707182257211562 0.337825155329684 0.0479997303551703 +Golgi apparatus subcompartment 30 96 3.662858630590687 0.0002494162025963 23.898058252427184 88.56796116504854 0.6438651907142603 0.5157075238910589 9.044082768463602 13.85685287398648 1.2182273227220288 0.3801323692583779 0.0217287085038183 1.0 0.1261943205571607 0.015072680493098 0.0017341543529716 +Golgi cisterna 15 27 3.588927977085724 0.0003320405497644 8.524271844660195 22.490291262135923 0.9086972174309816 0.318868202549777 4.2525712614684625 5.269200019661922 1.391079392561209 0.3149122340418913 0.0246460482062915 1.0 0.0338721796728873 0.0082077294132096 4.309476059245743e-05 +Endoplasmic reticulum lumen 28 69 3.560702163810791 0.0003698644215215 18.07766990291262 59.737864077669904 0.9896277047863468 0.3946249358858228 7.513340007333169 6.273245958458151 1.4320597420402308 0.3846324865730224 0.0153629021225293 0.559981185156499 0.8103851885086304 0.0521259527005788 0.0081546278577462 +Copii coated er to golgi transport vesicle 20 32 3.5285822443355697 0.0004177921000827 10.810679611650484 32.4247572815534 0.9209697551014924 0.3949407296339237 5.01338814607213 3.9617918728777735 1.2509556054930144 0.3456813773327062 0.1511289419871595 0.2766173679843171 0.1378217675082697 0.2193268794643932 7.978277875658614e-05 +Secretory granule membrane 30 80 3.485242944345749 0.0004916903981153 19.699029126213592 69.8495145631068 0.9295860214656708 0.3887665887416008 7.284889203542463 7.49087955205396 1.5950364553562375 0.3903287060113383 0.0014018942523687 0.0559390979061329 0.0082676305628072 0.0044088473407 7.022548533200245e-06 +Vesicle membrane 75 282 3.4743352398904856 0.000512120763727 59.03398058252427 252.66747572815535 0.5350285241159404 0.6113983912197217 17.512237349079548 29.567983380691818 1.3292572988488431 0.402876017449685 0.0007077078018966 0.0729794618679658 0.001079783381517 0.0004052868274878 4.649110888460954e-05 +Golgi stack 15 36 3.437603025629693 0.0005868874093748 9.67233009708738 31.25242718446602 0.7055900861920908 0.4265468940333196 4.557817503574521 5.847941213698429 1.2226912303929196 0.3463938041520717 0.0815973148153236 1.0 0.0698203966159025 0.031009617990344 0.0008853393332325 +Golgi cisterna membrane 10 20 3.3690892675257524 0.0007541699948014 6.233009708737864 17.101941747572816 0.7930989258143627 0.3092897028410761 3.2184356191878685 3.952300069740005 1.3504727992091758 0.2953094162507478 0.0754715823975887 1.0 0.0139156518076104 0.0362911702166911 3.176403402652151e-05 +Secretory vesicle 81 281 3.307001940643097 0.0009430023872281 56.25485436893204 257.47087378640776 0.1341228551105892 0.6386901443364594 16.601865631745117 19.12774191814033 1.3029114519128766 0.3900514633935764 1.35107297106892e-07 0.0191206051527279 0.0036130145664356 2.056662717413882e-05 1.1990254178660947e-11 +Endoplasmic reticulum protein containing complex 24 64 3.29889303331784 0.0009706689109405 20.067961165048544 61.213592233009706 0.544324442160867 0.4875881372361492 7.672624563199495 5.300944201362535 1.5348103009085623 0.3893079894443684 0.0001164516625398 0.0948632313276182 0.0207919883966976 0.0045318552746038 6.208591786146344e-05 +Endocytic vesicle 26 92 3.237717073909218 0.0012049023596465 19.521844660194176 83.27669902912622 0.428513908443532 0.5353120905813061 7.647069906220736 7.607555057832984 1.324058617895936 0.3761698531660883 0.0104329890563126 0.6294205244747506 0.01433463197651 0.0260669626113182 0.0049549100492084 +Azurophil granule membrane 20 26 3.2245655773283066 0.0012616395769908 7.856796116504855 21.259708737864077 1.0757479237162697 0.2373572682944545 3.393508570011604 2.63895903142419 1.639408148995933 0.2881313440808664 0.0026973635349428 0.1991580424676108 0.0733374275738533 0.0048028453089964 5.671648619941003e-05 +Exocytic vesicle 21 46 3.2145623938309287 0.0013064351911962 12.106796116504857 38.40533980582524 0.7408080162244459 0.4227017753873355 4.952517495270036 4.6543925000719675 1.3317240485888555 0.365166844745196 0.0245559733091491 0.4829170776296618 0.3817170987693297 0.1109800534398506 0.0003117084370037 +Respirasome 26 46 3.1874079635795467 0.0014355413665338 15.08495145631068 43.37378640776699 1.2524823540042158 0.2922262294299136 6.290312072426717 4.489587979561489 1.7783434517583476 0.3462844006183536 1.0341965509067246e-05 0.0078165677457274 0.0092927708056161 5.692764928188808e-06 2.701437551586633e-06 +Transport vesicle membrane 25 46 3.127335923600362 0.0017639824926682 12.62135922330097 42.37378640776699 0.5402420874587609 0.5343084089707166 5.404271063272784 4.511161156897919 1.052801184280702 0.3556606283757049 0.1032416233881617 1.0 0.3572711778500047 0.2010360447279547 0.0014672663901976 +Proton transporting two sector atpase complex 12 23 3.112902747289251 0.0018525705342462 7.116504854368932 22.25728155339806 1.0735578367707936 0.2848832687688338 3.2910616544032156 1.9833825153714253 1.32099194967518 0.2987458873835026 6.457966082269803e-05 0.0115082778780227 1.7352415807134444e-05 1.3471769237547282e-05 0.0001753252601336 +Pigment granule 28 62 3.0680353296466496 0.0021547114206792 17.058252427184467 60.37135922330097 0.3452760243889364 0.5728855837677844 7.454164461546019 2.3255555964379067 1.200064167427868 0.3798846852248331 0.0064245976418751 1.0 0.2175203628221676 0.0662267021572276 0.0041393793420635 +Snare complex 10 18 3.0351940100403967 0.0024038100330241 6.20873786407767 15.79368932038835 0.8138466711937282 0.3737991711938105 3.1112263618988054 3.010283181947674 1.1802712183474584 0.3261149602927671 0.0424943645739179 1.0 0.0651781855152293 0.0195417527514502 0.0009526402681126 +Endosome 62 231 3.014586219813474 0.0025733005875561 49.68446601941748 210.85679611650485 0.3589512364806963 0.6263779709054735 15.417095902733692 27.960293924368397 1.2603534839168704 0.3964197633252465 0.0069731336772823 0.649629396846267 0.0150386652660725 0.0080172563921348 0.0008571484436589 +Cis golgi network 8 17 3.0022638782266085 0.0026797977376562 5.446601941747573 14.91747572815534 1.304763677188147 0.2415633778835601 2.9087352716231463 3.2280604409731746 1.23405443481851 0.2890539664507128 0.0065434984200872 0.01497108596825 0.006299868694297 0.0140312853386763 0.000479523089417 +Synaptic vesicle membrane 9 18 2.896887305400732 0.0037688511285089 5.099514563106796 14.07766990291262 0.7734258277348643 0.4227625879426745 2.579286376297321 2.2325453295101236 1.0485572818049853 0.3297289695807819 0.010895757472073 1.0 0.4495131201040838 0.0593060830293246 0.0025715943576382 +Mitochondrion 195 660 2.8718764999960285 0.0040804239728138 150.5606796116505 610.75 0.3893280889581553 0.5444893646695418 55.48150839960472 53.47985851692477 2.1394883185001157 0.4272675793576402 3.6268745365434335e-14 1.259520697117891e-09 1.616470285022662e-07 4.200996879456617e-13 2.8132931557315647e-19 +Outer mitochondrial membrane protein complex 10 16 2.8403408238225567 0.004506535713167 7.157766990291262 15.730582524271844 1.3245491566248977 0.2112996285983387 3.5767402396348245 0.8689557679680192 1.477430451036954 0.2853006280851536 1.3490756268970628e-06 0.0040679264544396 0.0008978593047678 0.0011814468070448 1.4750631476459234e-07 +Golgi associated vesicle 9 32 2.839810517247045 0.0045140338090545 6.745145631067961 30.33009708737864 0.696501539533066 0.3869218626415568 3.3093865809086713 3.3403631844705557 1.2881306559419168 0.3350067162782171 0.0010961358165503 0.0421554091664212 0.0042348756279302 0.0012097891796545 0.0015503267588381 +Intrinsic component of golgi membrane 8 10 2.7913066713716868 0.0052495707782849 4.655339805825243 10.08495145631068 1.3178763872097854 0.2129685736028588 2.6046347098798024 1.9780511021437377 1.2704958978874823 0.2699640456705705 0.0016743512850917 0.1835089509173778 0.3367676981326228 0.0801176308941427 0.0001500964424578 +Cytochrome complex 11 17 2.7714960775596413 0.0055799344581317 6.021844660194175 16.08495145631068 1.0267019648816196 0.2321293206617183 2.9315837025395948 1.6175814223208935 1.624269406530766 0.2919563386676546 0.000212184877001 0.0084566179175882 0.0027014769688677 5.5308739194744206e-05 0.000378511976274 +Secretory granule 67 249 2.7236703688000907 0.0064560907491892 49.29854368932039 231.6504854368932 0.0742534337219474 0.6450440279734955 14.609170474630965 16.529443419678444 1.2643241567239918 0.3828342632667716 1.718057137383052e-06 0.0265490092744148 0.0067002842234809 3.523886220416438e-05 6.671080269821417e-10 +Presynapse 26 97 2.6755203373512058 0.0074613346138134 22.813106796116504 90.997572815534 0.4365135448276876 0.6534842370695999 7.919284748658944 8.50627945845188 0.826940228235506 0.3445781590237917 0.3739452240163189 0.7490691544617561 0.7656936867488215 0.6832131032627471 0.0598591840891809 +Organelle envelope lumen 15 43 2.667802309552631 0.0076349167528961 11.436893203883496 36.55339805825243 0.6276066761486734 0.4428242266058088 4.702137301503097 3.7796803567009714 1.1382138566471218 0.3469405856623805 0.0001455715047674 1.0 0.538739338785351 0.0001130369697303 9.705083787751065e-07 +Side of membrane 18 81 2.6556697367192386 0.0079151089323556 17.526699029126213 71.19660194174757 0.4235531336200628 0.5236659753791312 6.9409272887607125 8.635706418493163 1.198097658489356 0.36822581052137 0.083604883657158 0.7031108627898817 0.700644396796877 0.0793833993190269 0.0346543616361005 +Organelle membrane contact site 13 19 2.613242865994905 0.0089687543778664 6.817961165048544 16.400485436893202 0.815819301321945 0.3904411977369264 3.451940177462974 2.047328298639296 1.2919706717077657 0.3464717655445403 0.0040775097697983 1.0 0.0046396659223567 0.051542815486873 0.000217728528826 +Endocytic vesicle membrane 14 47 2.6021814528880256 0.0092632826202472 11.41019417475728 40.75728155339806 0.6528171904926832 0.3529092384633215 4.825015011915381 4.780047567333447 1.5638167276319088 0.3380752375601685 0.0597124418957146 0.4215392305763319 0.0240886081379492 0.0555655068618841 0.0988928907574591 +Early endosome 37 109 2.5591988896372677 0.0104913699130615 24.66504854368932 96.93203883495146 0.530758374709677 0.5743319290889299 8.086272783051246 14.025470683081796 1.1449007118883376 0.3721207721610414 0.0535884899689951 0.3946315037249025 0.2931782137767423 0.040639841516262 0.0104987284650824 +Er to golgi transport vesicle membrane 10 21 2.554033860467377 0.0106482900801005 6.495145631067961 21.890776699029125 0.3958870084748403 0.5141628679854253 3.1618901389258056 2.1225127942575894 0.9657155478739712 0.3164691847513972 0.7482456782386024 1.0 0.3496381161424667 0.6593533907576883 0.018870184963526 +Zymogen granule 3 5 2.5404489196803217 0.0110710264154523 1.5218446601941749 3.888349514563106 0.1571223115185814 0.3969732660735861 0.9174725175882594 0.8714234500493322 1.2261793354789892 0.3097871532699415 0.2214576049043232 1.0 0.075113296023457 0.1775366954381628 0.0053334351931861 +Golgi associated vesicle membrane 6 21 2.532203037541842 0.0113348336131215 4.201456310679611 19.589805825242717 0.79417597045559 0.3511132904952779 2.457541951272857 2.384047500904294 1.2111660039755976 0.3110721945776767 0.0001910003220597 0.0157111699130222 0.0005845317815958 0.0003579470321216 0.0028457755604085 +Phagocytic vesicle membrane 12 27 2.5272127656215733 0.0114971827036336 7.512135922330097 23.83009708737864 0.5348434256443761 0.4468744105904624 3.681144332021715 3.0024693704800938 1.1652764437248655 0.3385441964418395 0.1180805377402906 1.0 0.1182995834221419 0.1820516573570916 0.0750518175373725 +Endosome membrane 38 139 2.5047345027109893 0.0122543340944729 28.436893203883496 125.75485436893204 0.1968108610887141 0.5657595498250074 10.058247741499075 16.477863960688197 1.2734596099850304 0.3756178998455078 0.0270343127233131 0.552983765901358 0.0777434038380522 0.0226736049548766 0.0064614058956907 +Proton transporting atp synthase complex 8 12 2.464508336440077 0.0137201371889703 4.157766990291262 11.08495145631068 0.5328143574617974 0.3012358599713604 2.3610641964760792 1.138499586439592 1.3748267965121657 0.2836171984539964 0.0015284527669486 0.0029386578360865 0.0115435449528709 0.0006143549700213 0.0010145405611514 +Phagocytic vesicle 15 46 2.4595378425463506 0.0139116030459718 11.54126213592233 41.59708737864078 0.3919256884663005 0.5681630099638236 4.854259100699266 4.0100348958770144 0.9938295058309184 0.3509625084864278 0.0879497861389108 1.0 0.0732279741082547 0.0940079969551786 0.0540545271546236 +Respiratory chain complex iv 7 11 2.437952553395042 0.0147707125749352 3.754854368932039 9.74271844660194 0.8119042784517004 0.2590637228606872 2.032646352020888 1.0643473720992946 1.3870085883810457 0.2875864020654643 0.0019179537012613 0.083126337411673 0.1611939416425752 0.0007750266814789 0.0013491401517078 +Intrinsic component of peroxisomal membrane 1 5 2.4358735390459048 0.0148558771983202 1.9320388349514563 4.434466019417476 0.5069121698582412 0.444591863161664 1.4960279832433574 1.753796563107492 1.0627811042818465 0.325067944975853 0.3747076822525905 1.0 0.1362380906066266 0.3069124011154697 0.16360549489043 +Coated vesicle membrane 15 58 2.428878669415114 0.0151455998707843 12.470873786407768 56.310679611650485 0.4487003631021872 0.5093312281655428 5.273732877175169 4.573093801439982 1.1487677393522833 0.3682374685669872 0.071826970048759 0.0189208145590584 0.0057471397407531 0.1563659949679706 0.0121060150206101 +Intrinsic component of mitochondrial outer membrane 6 12 2.424826117993495 0.0153157204823497 5.004854368932039 12.186893203883496 0.537559322132711 0.4142348023165385 2.5976045215999015 2.144426747635188 1.2224430201503769 0.3320793466689031 0.1569285299286972 1.0 1.0 0.4301270919610729 0.0043329575683166 +Microbody membrane 10 31 2.396715573137356 0.016542759295558 9.83980582524272 26.8373786407767 1.0322166739723002 0.3740701224912098 5.101262737371427 4.075770333088885 1.3138416014090577 0.3534887732287703 0.0078848703403328 0.2406936845278361 0.1057169178564165 0.0118522943314895 0.0059899182032361 +Lumenal side of membrane 6 10 2.389129690942769 0.0168883395186754 3.686893203883495 9.509708737864075 0.6270696996832885 0.3351332813726532 1.8490414883089543 0.9791034697552432 1.2332692274886168 0.3003490996154719 0.0288824454338437 1.0 0.1933613304033528 0.0152248647419399 0.0004920431328091 +Copi coated vesicle membrane 3 13 2.3662247586804046 0.0179705310070257 2.9611650485436893 12.451456310679612 0.9351146201256926 0.2894293018559171 1.7580457491925867 1.2208038158644114 1.2401568068418547 0.2855671555488221 0.001197611569951 0.0026008925831016 1.391730242568295e-05 0.0004788146962384 0.00630824692371 +Proton transporting two sector atpase complex proton transporting domain 7 10 2.318554528823489 0.0204192030657277 4.053398058252427 10.283980582524272 1.020958321179617 0.2307004649223604 1.8491832641634656 1.1862626633334956 1.3576055733210162 0.273185751006507 6.248506710619771e-05 0.0022827689145391 1.0516191954151127e-05 1.934192081629664e-05 0.0005338561483377 +Respiratory chain complex iii 2 8 2.31402051954739 0.0206665965977899 2.5145631067961167 7.186893203883495 0.8648567981956616 0.2640480169416735 1.5224155414895728 0.9433070612984726 1.3007640218760226 0.2795290338624424 0.0065763731833925 0.0607401038440192 0.0067896670197663 0.0033170374819039 0.0227185425065092 +Intrinsic component of synaptic vesicle membrane 5 12 2.3019395803055684 0.021338579719607 3.648058252427184 9.116504854368932 0.724313202500786 0.4129003553732678 2.1933086936710184 1.7154408466980504 1.018214829869002 0.3297596143558817 0.0088487425283697 1.0 0.2318581098993339 0.0264830942684438 0.0015869747860804 +Tim23 mitochondrial import inner membrane translocase complex 3 6 2.2971290362964507 0.0216114098096364 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 0.0039714533726283 0.0012105019492812 0.0048484802924912 0.001983278822638 0.00138858926748 +Early endosome membrane 14 52 2.2818614289768977 0.0224975226741184 12.29611650485437 44.95873786407767 0.5277524243262064 0.5849546522697281 4.982462882428341 7.094079738701261 0.90392558948614 0.3412735259006035 0.0881560227515605 0.4517357114503159 0.703965257139979 0.0793927108250854 0.0071973864359223 +Proton transporting v type atpase complex 2 11 2.267569275039768 0.0233554721384063 3.1723300970873787 11.17233009708738 1.083137374920517 0.3054753623634815 1.8106779848505148 1.1913569842207026 0.9186852151104662 0.2868810804648729 0.0142767807743484 1.0 0.0005470061355849 0.0073447144383531 0.0468003866103798 +Transporter complex 38 66 2.2417061501819844 0.0249803701377857 16.033980582524272 55.199029126213595 0.256193630237002 0.358562058071074 7.704418772430675 7.665912382074106 1.666161547187811 0.3440522205931707 0.0020388653000683 0.0339714602069511 0.0557509171156544 0.0030848714002588 9.126665418877596e-06 +Cell surface 22 88 2.222250559735717 0.0262663773197255 21.233009708737864 77.5995145631068 0.4772545566224628 0.498248600191797 7.455308766626032 8.832436895439663 1.3320096182828691 0.3812427248674431 0.3783244284667288 0.7859178232186557 0.366102239218816 0.3501792188017755 0.1344915184098951 +Rough endoplasmic reticulum 11 37 2.186105089967896 0.0288079176976459 8.516990291262136 34.51699029126213 0.6279779058801568 0.506302031213321 4.715930723848554 2.6644372563657086 1.002611026388539 0.3540125587222381 0.0002552108024082 1.0 0.0995728547031488 0.0003302169514715 5.512316207184221e-05 +Copi coated vesicle 3 14 2.1825532588850547 0.0290687250982157 3.366504854368932 13.565533980582524 0.927757948703832 0.3021632050419245 1.9356503178232003 1.3008870969982682 1.2180478421179144 0.2957691490409697 0.0028928603294508 0.0040679264544396 3.5959740301631905e-05 0.0011814468070448 0.002252196025852 +Golgi lumen 2 5 2.176370445392827 0.0295275718785612 1.745679012345679 4.548148148148148 1.1368717941323 0.2457507117503182 1.2159484823715767 1.4039724163790972 1.161880305109492 0.2643265801751675 0.2587598307380946 1.0 0.2685353106225043 0.1800390494619342 0.2023846543655014 +Mitochondria associated endoplasmic reticulum membrane 8 10 2.1721461646009663 0.0298446398363727 4.191747572815534 9.240291262135925 0.7019541594808174 0.4009163152547425 2.0831338076447135 1.0418560326821893 1.1194321867771957 0.3336055532093068 0.1046893250830714 1.0 0.1611939416425752 0.3559534457378639 0.0013491401517078 +Lumenal side of endoplasmic reticulum membrane 5 8 2.170624152492501 0.0299595948362725 3.0776699029126213 7.361650485436893 0.5475818769285827 0.3637002691484017 1.5990854205757892 0.8689828861838115 1.1522443815379428 0.2937666584254462 0.1046893250830714 1.0 0.1611939416425752 0.0688460117016781 0.0013491401517078 +Trans golgi network membrane 12 28 2.1207494398239333 0.0339428935630379 7.097087378640777 25.808252427184467 0.4300178223009387 0.4839581535123586 3.4857952056404495 4.861642003007495 1.0577526504941306 0.3235584371830635 0.0204773698476098 1.0 0.4960773916621825 0.0266777247012389 0.0065607705696853 +Anchored component of synaptic vesicle membrane 1 5 2.1034461721500075 0.0354267859367347 2.237864077669903 4.206310679611651 0.1314197356628333 0.5926814944822772 1.2928944351183786 0.7874371484134337 0.8244891142435123 0.294827647016494 0.0361319669005298 1.0 1.0 0.2167775624926856 0.0820486275159116 +Mib complex 5 10 2.045681830340152 0.0407876845369996 4.669902912621359 10.016990291262136 0.8674199579421746 0.3102009046029466 2.3929035436504367 0.6011337749949848 1.2568635951567688 0.31203902687269 0.000506203921404 1.0 0.1191939669275513 0.0379575415698398 0.0002481332774246 +Microbody 18 60 2.034545796514568 0.0418965960787567 14.5873786407767 55.157766990291265 0.5308798958236631 0.4622505798174944 6.656600193656261 6.967459933597681 1.141402376279513 0.3502304815174672 0.0007573872922586 0.4243503559946278 0.0990612642216925 0.001715784629106 0.0012316476116813 +Specific granule membrane 5 20 1.995882059346404 0.0459467619576123 4.703883495145631 15.434466019417476 0.8701513897757543 0.3699585460258285 2.477017558764293 2.6655071934549124 0.9998631482292508 0.308737972868479 0.0633567005786475 0.0230489069918226 0.0818055658939264 0.1140816659952819 0.0305407497227627 +Trans golgi network 17 68 1.974304124577146 0.0483471721969472 15.419902912621358 63.34466019417476 0.3899535194812628 0.596168565313415 5.947659406670704 9.796108085479462 0.9254595120691144 0.3511819564605877 0.1544998051844969 1.0 0.5736393148922796 0.1988152983910212 0.0569840849594662 +Protein lipid complex 1 5 1.960747405589064 0.0499084960826317 0.9733009708737864 4.152912621359223 0.8806614337674874 0.2932450111231078 0.8822773800999041 1.1227636940840768 1.0732388951245535 0.2459144485958364 0.3939928003913119 1.0 0.144637307685789 0.3236592382947187 0.1812716861639223 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ccf6c0139f3a7e4be957da708a4d11b596e11611 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 911, + "title": "Average number of proteins per term", + "value": 30.6827661909989 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0b0fa693099bfbde383a73a4a39a1d73e4a03806 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..640f2ed788e3c9c1d8d63789c34f7b209a6eedc2 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,312 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Endoplasmic reticulum 0.5690364544432216 7.927439064022439 2.237112259415903e-15 2.0389202683258114e-12 2.0389202683278874e-12 521 P24390,Q14108,P49069,Q00765,Q8N0U8,Q15125,O15173,P05023,P30519,P48651,O43731,Q9BT22,P80303,O95881,Q13510,Q13445,Q6NUK4,P43307,P13674,Q9H6V9,P16615,O00264,O15260,P09601,P53634,P04439,Q9Y282,Q8IV08,Q9BQE5,O95772,Q14849,P49257,P51809,Q8IY95,Q9Y5Y5,Q15629,Q5BJF2,Q8N511,O95433,Q8N2F6,Q9BRR6,P04062,P67812,P33908,Q6NUQ4,Q8TCT9,Q5J8M3,Q96JX3,Q16880,Q15363,Q14696,Q07812,Q9Y2G5,Q9H0U3,O75844,O75503,Q9P2W9,O95470,Q14257,Q86YN1,Q9H3N1,Q9Y5M8,Q9HD20,P30536,P78536,Q96AG4,P10619,P51648,O60762,Q8TCJ2,O60725,Q9Y394,Q8TB61,P57088,Q92791,Q9Y2B2,Q16850,Q9BTY2,Q8IY17,P06493,Q86XL3,O15027,P52789,Q92604,Q96AA3,Q9NWM8,O95864,Q5T9L3,Q96KC8,P27544,Q15041,P35613,Q8TBX8,Q15382,O95197,O95302,P05067,Q15293,Q9BUN8,P51151,Q9Y680,Q13438,Q15800,P18031,Q9UKU0,Q8NBQ5,Q70UQ0,O75298,P38435,Q9UMX5,Q96G23,Q9NQC3,P07099,O43464,Q96A33,Q8N2K0,Q8TCT8,O00584,Q07065,O43292,O95070,Q9UBV2,Q9GZP9,O95456,O43852,O15269,Q9H9S5,Q96HY6,P27105,P48723,O15118,O75718,Q96JJ7,Q9P035,Q6P179,Q9NPA0,P61916,Q8N5M9,P50402,O60506,Q14534,Q10472,Q32P28,Q9BVK6,Q9BVG9,Q99735,P10909,P84157,Q7L0J3,Q9NR31,Q15392,P46977,P49755,Q92542,Q96N66,O75845,O14681,P20073,Q96S66,Q9H0P0,O15258,Q9H6H4,Q9Y3A6,Q9UMX0,Q9BQT9,O15498,Q13190,P01889,Q01105,Q86Y07,Q9H2J4,P51572,Q99720,P61019,P16435,Q14739,Q8WVQ1,Q969X5,Q99442,Q86UL3,O43390,O60476,O95674,Q8NHH9,Q96PC5,Q9Y6I9,Q86UE4,Q9NZ08,A1L0T0,P51571,P55327,P10321,P98194,Q9BU23,Q86YV9,Q9Y4P3,Q9UQB8,Q53GQ0,O15460,Q13501,Q6NUM9,Q9H223,O43681,O75915,P04843,Q12981,Q9Y3E0,Q9UHB9,Q9H6S0 209 +Organelle subcompartment 0.5850106885654379 7.7199978774376 1.1633164284792658e-14 1.0598723663390008e-11 5.2993618317230554e-12 399 P24390,Q14108,P49069,Q00765,Q8N0U8,Q15125,P30519,P48651,O43731,Q9BT22,O14828,Q13445,Q6NUK4,P43307,P16615,O00264,O15260,P09601,P04439,P53365,Q9Y282,Q8IV08,Q8TBA6,Q9BQE5,O95772,Q14849,P49257,P51809,Q9BXS4,O43752,Q9Y5Y5,Q15629,Q5BJF2,Q8N511,Q8N2F6,Q9BRR6,P04062,P67812,Q6NUQ4,Q5J8M3,Q8TCT9,Q15363,Q07812,Q9Y2G5,Q9H0U3,O75844,O00461,Q8NBZ7,Q9P2W9,O95470,Q9H3N1,Q86YN1,Q9Y5M8,Q9HD20,Q9HC07,O95249,O15127,Q96AG4,P51648,O60762,Q8TCJ2,O60725,Q9Y394,Q8TB61,P57088,Q9Y2B2,Q16850,Q8IY17,P40616,P06493,Q86XL3,O15027,Q92604,Q96AA3,O95864,Q5T9L3,Q96KC8,P27544,Q15041,P35613,Q15382,O95197,P51151,P05067,Q9BUN8,Q13438,Q15800,Q9UKU0,Q70UQ0,O75298,P38435,Q96G23,Q9NQC3,P07099,O43464,Q96A33,Q9BZG1,Q8N2K0,Q8TCT8,Q07065,O60499,Q10713,O43292,O95070,Q9UBV2,Q9GZP9,O43852,O15269,Q96HY6,Q96JJ7,Q9P035,Q6P179,Q9NPA0,Q9NPR9,Q8N5M9,P50402,P09496,Q14534,Q10472,Q9BVK6,Q9BVG9,Q99735,Q15392,P46977,P49755,Q96N66,O75845,O14681,P20073,Q96S66,Q9H6H4,Q9Y3A6,Q9NX62,Q9BQT9,Q13190,P01889,Q86Y07,P51572,Q99720,P61019,Q9H4A5,P16435,Q14739,Q8WVQ1,Q9H4A6,Q969X5,Q99442,Q86UL3,O95674,Q4J6C6,Q8NHH9,Q96PC5,Q9Y6I9,Q86UE4,Q9NZ08,O15126,A1L0T0,P51571,P10321,P98194,Q9BU23,Q9Y4P3,P0CG08,Q53GQ0,Q6NUM9,O75915,P04843,Q12981 168 +Intrinsic component of organelle membrane 0.7106785517621718 6.950076224274474 3.650888957498217e-12 3.325960745755939e-09 9.088491711344904e-10 140 O60830,O14925,Q9GZP9,P49069,Q99595,Q8TB61,Q15125,Q9BPX6,P42892,P01889,Q9Y2R0,Q9BWH2,Q9H9P8,Q86XL3,Q5XKP0,Q6ZRP7,Q9H3K2,P51572,Q9NX63,O15118,Q5T9L3,O75880,Q13505,Q15041,Q9P035,Q14739,P20339,Q9GZY8,Q9Y282,Q9NPA0,Q969X5,Q9BUN8,O43505,L0R6Q1,Q99442,O43752,Q9Y287,Q6UXV4,O15126,Q9Y5Y5,Q15629,Q9UG56,O75298,Q9NWR8,P17152,P10321,P98194,Q8TCT9,Q9Y4P3,Q6P4A7,Q7L0J3,Q9NQC3,O75844,Q5HYI7,Q8IWA4,Q96A33,Q8TCT8,O95470,Q86YN1,P61020,Q8N8Q8,O60499,P57105,O43808,O43292,O95070,Q15388,O15258 68 +Nuclear outer membrane endoplasmic reticulum membrane network 0.5958641463892145 6.9375155122527055 3.9905551850032514e-12 3.6353966779371615e-09 9.088491711344904e-10 331 P24390,Q14108,P49069,Q8N0U8,Q15125,P30519,P48651,O43731,Q9BT22,Q13445,Q6NUK4,P43307,P16615,O00264,O15260,P09601,P04439,Q9Y282,Q8IV08,Q9BQE5,O95772,Q14849,P49257,P51809,Q9Y5Y5,Q15629,Q5BJF2,Q8N511,Q8N2F6,Q9BRR6,P67812,Q6NUQ4,Q5J8M3,Q8TCT9,Q15363,Q07812,Q9Y2G5,Q9H0U3,O75844,Q9P2W9,O95470,Q9H3N1,Q86YN1,Q9Y5M8,Q9HD20,Q96AG4,P51648,O60762,Q8TCJ2,O60725,Q9Y394,Q8TD16,Q8TB61,P57088,Q9Y2B2,Q16850,Q8IY17,P06493,Q86XL3,O15027,Q92604,Q96AA3,O95864,Q5T9L3,Q96KC8,P27544,Q15041,P35613,Q15382,O95197,P51151,Q9BUN8,Q13438,Q15800,Q9UKU0,Q70UQ0,O75298,P38435,Q96G23,Q9NQC3,P07099,O43464,Q96A33,Q8N2K0,Q8TCT8,Q07065,O43292,O95070,Q9UBV2,Q9GZP9,O43852,O15269,Q96HY6,Q96JJ7,Q9P035,Q6P179,Q9NPA0,Q8N5M9,P50402,Q14534,Q10472,Q9BVK6,Q9BVG9,Q99735,Q15392,P46977,P49755,Q96N66,O75845,O14681,P20073,Q96S66,Q9H6H4,Q9Y3A6,Q9BQT9,Q13190,P01889,Q86Y07,P51572,Q99720,P61019,P16435,Q14739,Q8WVQ1,Q969X5,Q99442,Q86UL3,O95674,Q8NHH9,Q96PC5,Q9Y6I9,Q86UE4,Q9NZ08,A1L0T0,P51571,P10321,Q9BU23,Q9Y4P3,Q53GQ0,Q6NUM9,O75915,P04843,Q12981 143 +Organelle inner membrane 0.5728513740716745 6.011869118562634 1.8339636563779663e-09 1.6707394977165771e-06 3.3414817837426544e-07 258 O60830,Q99595,Q9UDW1,P20674,Q9Y2R0,Q9UDX5,P00846,Q9H9P8,O43676,Q69YU5,P06576,O75964,P00403,Q70HW3,P62995,Q9H2D1,P22830,Q16540,Q9UBX3,O43615,Q7Z7F7,O95298,Q9Y5L4,Q9Y512,Q9NPL8,Q6P4A7,O95831,O75844,Q5HYI7,O14949,O94901,Q9Y619,O95202,P03886,P22695,P15954,P10606,Q13423,Q5T9A4,Q567V2,P56385,O14925,P14406,O96008,Q9BSK2,Q6DKK2,P56378,Q9H1E5,O43772,Q9H061,P12236,Q9H2V7,Q9Y2C4,Q9NX14,Q13505,Q8N183,Q6NUK1,P18031,O95168,Q86Y39,Q9BRJ2,Q9Y5J9,P13073,Q02978,Q96NB2,P14927,Q8NI60,P24539,Q9P015,Q8NBN7,Q9H9B4,O60220,Q9BRT2,P12235,Q8N8Q8,Q9BTV4,Q8NE86,Q03252,Q9Y4W6,Q10713,P23786,P20700,O14548,Q96CU9,Q9BPX6,P82933,Q5XKP0,Q9H3K2,Q9NX63,Q9Y6C9,Q9BQT8,P50402,O75208,Q9UG56,P10909,Q3ZCQ8,P36542,Q9NQ50,Q9NVI7,Q8IYU8,O75438,O75306,P09669,Q99720,O75880,P36551,Q14739,O95674,Q9Y5J7,Q6UXV4,O60313,Q9NWR8,P17152,Q9BUB7,O75489,Q9H936,P53701,P56134,Q96IX5 119 +Mitochondrial envelope 0.527921518533491 5.929421395040353 3.0400399732905235e-09 2.7694725857920443e-06 4.615794027631112e-07 338 O60830,Q9NS69,Q99595,Q9UDW1,P21796,P20674,Q9Y2R0,Q9UDX5,P00846,Q9H9P8,O43676,Q69YU5,P06576,O75964,Q8N4H5,P00403,Q70HW3,Q9H2D1,P45880,O00264,P09601,P22830,Q9UBX3,Q16540,Q8WY22,O43615,Q7Z7F7,O95298,P50416,Q9Y5L4,Q9Y512,Q9NPL8,Q96TC7,Q96A26,Q8WWV3,Q07812,Q6P4A7,O95831,Q5HYI7,O14949,Q9Y619,Q9Y3B8,O95202,P03886,P22695,P57105,P15954,P10606,Q9NQ88,P30536,Q13423,Q567V2,Q5T9A4,P56385,O14925,Q9NVT9,P14406,Q9BSK2,O96008,Q6DKK2,P56378,O43772,P52789,Q9P0S9,Q9H061,Q9H2V7,P12236,Q8N183,O43169,Q13505,Q9Y2C4,Q9NX14,Q6NUK1,Q9Y277,P18031,O95168,Q86Y39,Q9UKU0,Q9BRJ2,Q9Y5J9,P13073,Q02978,Q96NB2,P14927,Q8NI60,P24539,Q9HCL2,Q9P015,Q8NBN7,Q9H9B4,O43464,O60220,Q9BRT2,P12235,Q9NR28,O00584,Q8N8Q8,Q8NE86,Q9Y4W6,Q10713,P23786,Q15388,O14548,Q8NBU5,Q96CU9,Q9BPX6,P82933,Q8N2A8,Q5XKP0,Q9H3K2,Q9NX63,Q9Y6C9,Q9BQT8,O75208,Q9UG56,P10909,Q3ZCQ8,Q8IWA4,P36542,Q9NZJ7,Q9NQ50,Q9NVI7,Q96BR5,Q8IYU8,Q9BWH2,Q86Y07,O75438,O75306,P09669,O75880,P36551,Q9GZY8,Q9H4A6,O95674,Q9Y5J7,Q6UXV4,P0DP25,O60313,Q9BXK5,Q9NWR8,P17152,Q9BUB7,Q9NQZ5,Q9NZ45,O75489,Q07820,Q9H936,P53701,P56134,Q12981,Q96IX5 151 +Envelope 0.4552120059093364 5.672622313190552 1.4062804516460354e-08 1.2811132942222677e-05 1.830173559343769e-06 519 O60830,Q9NS69,Q99595,Q15125,O15173,Q9UDW1,P21796,P20674,Q9Y2R0,Q9UDX5,P00846,Q9H9P8,P80303,O43676,Q69YU5,P06576,O75964,Q8N4H5,P00403,Q70HW3,Q9H2D1,P45880,P62995,O00264,P09601,P22830,Q9UBX3,Q16540,Q8WY22,O43615,Q7Z7F7,O95298,P50416,Q5BJF2,Q9Y5L4,Q9Y512,Q9NPL8,Q96TC7,Q96A26,Q8WWV3,P50995,P42167,Q07812,Q6P4A7,O95831,O75844,Q5HYI7,O14949,O94901,Q9Y619,Q9Y3B8,O95202,P03886,P22695,Q9C0E2,P57105,P15954,P10606,Q9NQ88,P30536,Q8N201,Q13423,Q567V2,Q5T9A4,Q96AG4,P56385,O14925,Q9NVT9,Q8TD16,P57088,P14406,Q9BSK2,O96008,Q6DKK2,P56378,Q9H1E5,O43772,P52789,Q9P0S9,Q9H061,Q9H2V7,Q96KC8,P12236,O43169,Q13505,Q8N183,Q9Y2C4,Q9NX14,Q6NUK1,P05067,Q9Y277,P18031,O95168,P41208,Q86Y39,Q9UKU0,Q9BRJ2,Q9Y5J9,Q9BTX1,O15504,P13073,Q02978,Q96NB2,P14927,Q8NI60,P24539,Q9HCL2,Q9P015,Q8NBN7,Q9NQC3,Q9H9B4,O43464,O60220,Q9BRT2,P12235,Q9NR28,O00584,Q8N8Q8,Q9BTV4,P67809,Q8NE86,Q03252,Q9Y4W6,Q10713,P23786,P20700,Q15388,O14548,P27361,Q8NBU5,Q96CU9,Q9BPX6,P82933,Q8N2A8,Q5XKP0,Q6ZRP7,Q9H3K2,Q9NX63,O15118,Q9Y6C9,Q9BQT8,Q9P035,P50402,O75208,Q9UG56,Q99735,P10909,Q3ZCQ8,Q8NFH4,Q8IWA4,P36542,Q9NZJ7,Q9NQ50,O14681,Q8N1F7,Q96S66,Q9NVI7,Q96BR5,Q8IYU8,Q9BWH2,Q86Y07,O75438,O75306,P09669,Q99720,O43633,O75880,P36551,Q14739,Q9GZY8,Q9H4A6,O95674,Q9Y5J7,Q86UE4,Q6UXV4,P0DP25,O60313,Q9BXK5,Q9NWR8,P17152,Q9BUB7,Q9NQZ5,Q9NZ45,O75489,Q07820,Q6NUM9,Q9H936,P53701,P56134,Q12981,Q96IX5 191 +Golgi membrane 0.5874770316299485 5.5339385759418604 3.1311866647232645e-08 2.852470412601781e-05 3.565638814567492e-06 143 P24390,Q14108,Q8TB61,Q9BQT9,O15498,Q13190,P01889,O43731,Q9H9S5,Q16739,Q6ZRP7,P51572,P61019,Q9H4A5,Q5T9L3,O95721,P04439,O15260,P35613,Q9H4A6,O95197,Q9Y282,Q8IV08,Q8TBA6,O43505,Q969X5,L0R6Q1,O60476,P49257,Q8IZA0,O43752,Q9Y287,Q10472,Q9BVK6,P33908,P10321,P98194,Q8NCH0,Q92896,Q15363,Q7LGA3,P0CG08,Q15392,O00461,Q9P2W9,P49755,O60499,Q9HC07,Q10713,O95249,Q96S66,Q8NDZ4,O95070,Q9Y3E0,P51790,O15258 56 +Golgi apparatus 0.481972822831796 5.115504779663095 3.1290302325932825e-07 0.0002850140745568 3.167273935446211e-05 335 P50897,P24390,Q14108,P05023,Q96PU5,O43731,Q16739,P80303,O14828,Q13445,P53634,O15260,P04439,P53365,Q9Y282,Q8IV08,Q8TBA6,P49257,P51809,Q8IY95,Q8IZA0,O43752,P04062,P33908,Q5VW38,Q8NCH0,Q93050,Q15363,O75503,O14773,O00461,Q8NBZ7,Q9P2W9,Q9HC07,O95249,O15127,Q7RTS9,Q8TB61,Q68CQ7,Q9NQX7,Q5T9L3,P35613,O95197,P05067,L0R6Q1,Q9Y287,Q8NEY8,Q7LGA3,Q9BZG1,O60499,Q10713,O95070,Q8NEW0,P06280,O95456,O43852,Q9H9S5,Q8N2A8,Q6ZRP7,Q9NX40,O15118,O43505,Q9NPR9,P09496,Q10472,Q9BVK6,Q8N3R9,P10909,Q9NR31,Q15392,P49755,Q92542,Q99805,O14681,Q96S66,P51790,O15258,Q92544,Q9Y3A6,Q9NX62,Q9BQT9,O15498,Q13190,P01889,P46934,P16278,P51572,P61019,Q9H4A5,O95721,Q92520,Q8WVQ1,Q9H4A6,Q969X5,O60476,Q4J6C6,O15126,P10321,P98194,Q92896,P0CG08,Q9UQB8,Q8NDZ4,Q9Y3E0 104 +Inner mitochondrial membrane protein complex 0.6373718292674955 4.814743916386025 1.4738877589515198e-06 0.001341811702484 0.000123919722491 81 O60830,P56385,Q99623,O14925,Q99595,P14406,Q9UDW1,Q96CU9,P20674,Q9BPX6,P56378,P00846,O75438,O43676,P06576,O75306,Q5XKP0,P09669,O75964,P00403,Q9NX63,P12236,Q9NX14,Q13505,O95168,Q9Y5J7,Q86Y39,Q6UXV4,O95298,P13073,Q9Y512,Q9NWR8,P14927,P24539,Q3ZCQ8,Q5HYI7,O14949,P36542,O75489,P03886,P22695,Q8NE86,Q96IX5,P15954,P10606,Q9Y4W6,P56134,Q8IYU8,O14548 49 +Membrane protein complex 0.4775068822236645 4.811731019685204 1.4962864406159625e-06 0.0013621893439024 0.000123919722491 307 O60830,Q9NS69,Q13277,P05023,Q99595,Q9UDW1,P21796,P20674,P00846,O43676,P06576,O75964,Q8N4H5,P00403,P45880,P04439,Q9C0H2,P51798,P51809,O43752,Q9Y487,O95298,Q8N511,Q9Y512,P67812,Q5J8M3,Q8TCT9,Q93050,Q07812,Q9H0U3,Q5HYI7,O14949,O94901,P61421,Q9P2W9,Q9Y5M8,P03886,P22695,P15954,P10606,O95249,P56385,Q8TCJ2,O14925,P14406,P05026,O96008,P56378,Q5VZ89,P12236,Q9NX14,Q13505,Q15041,Q9BUN8,Q9Y277,Q13438,O60749,O95168,Q86Y39,P13073,P14927,P63218,P24539,P61009,O43464,Q8N2K0,P12235,Q9NR28,Q8NE86,O60499,Q9Y4W6,O43292,Q9P253,Q15388,O14548,Q9P0I2,Q9UBV2,Q9GZP9,Q99623,O43674,Q96CU9,Q9BPX6,Q86Y82,O15269,Q9UGP8,Q5XKP0,Q07666,Q9NX63,P25054,Q9UNH7,Q9NPA0,P21912,P54709,P09496,Q9UHA4,Q9Y6M9,O75340,Q6IAA8,Q4KMQ2,Q3ZCQ8,Q9Y5X3,Q9NR31,Q9Y6B6,Q8IWA4,P46977,P36542,Q03518,P49755,Q92542,P56556,Q53H12,Q9NVH1,Q96S66,P51970,Q8IYU8,Q14254,Q9H9H4,Q9BRG1,Q99996,P62942,O15498,Q13190,P01889,P00533,Q92572,O75438,O75306,P09669,P08195,O75947,O95721,O43633,Q9Y5J7,Q6UXV4,P0DP25,P51571,Q9NWR8,P10321,Q53GQ0,O15400,O75489,P04843,P56134,Q12981,Q8NDZ4,Q96IX5 146 +Intrinsic component of endoplasmic reticulum membrane 0.713423723910759 4.754767367554291 1.986750539195725e-06 0.0018082946007928 0.000150827478434 56 Q9GZP9,P49069,Q8TB61,Q15125,P01889,Q86XL3,P51572,P04439,Q15041,Q9P035,Q969X5,Q9Y282,Q99442,Q9NPA0,Q9BUN8,Q15629,O75298,P10321,Q8TCT9,Q9Y4P3,Q9NQC3,O75844,Q96A33,Q8TCT8,O95470,Q86YN1,O43292,Q12981 28 +Vacuole 0.4962007605915217 4.7235921783467 2.3171485887818477e-06 0.0021086983751562 0.0001623786434139 236 P00813,Q13277,P50897,Q14108,Q13510,P53634,O15260,Q99538,O75629,Q8IV08,P07602,P51798,P11279,O95772,Q14849,P51809,Q8IY95,Q9UMR5,Q9BXS4,P54802,Q9Y487,O95298,Q5BJF2,Q8N511,P04062,Q8NHP8,P50995,Q93050,Q9UHG3,Q9H0U3,O75503,O14773,Q8WTV0,Q01085,P13473,P61421,Q9HC07,P06865,P42785,P10619,P07858,P42892,P15586,Q9BTY2,Q9NQX7,P17900,Q9H2V7,O60749,P38435,Q9UIQ6,Q8TCT8,O00584,Q07065,Q9H0B6,P04066,Q05639,P06280,Q969Q5,P27105,Q9NX40,O15118,P11117,P61916,P09496,Q9UM22,Q15165,Q92542,Q9NZJ7,P10253,P22413,Q8IW92,P51790,Q9UMX0,P16278,P61019,O95721,O43633,Q9Y6I9,Q86YV9,Q16625,P08236,O15400,Q13501,O43681 84 +Vacuolar lumen 0.6088940476855397 4.4403843976456345 8.979833292732664e-06 0.0081472942813031 0.0004812134193929 70 P10619,P50897,Q14108,P07858,P15586,Q9BTY2,Q13510,P17900,P11117,O75629,Q8IV08,P07602,P61916,Q9UMR5,P54802,Q9UM22,P04062,P38435,Q8NHP8,O14773,O00584,Q9NZJ7,P04066,P10253,P06865,P06280 26 +Transport vesicle 0.5320115617589498 4.3047082396834995 1.672059490198663e-05 0.0151171602542382 0.0006066979769823 101 Q15907,Q13277,P50897,P24390,O15498,Q13190,P01889,Q92905,O43731,P04439,O15260,Q9GZY8,P20339,Q8TBA6,P05067,P11279,P49257,P51809,P09496,O43752,O15126,P0DP25,O43760,Q9BVK6,P10321,Q15363,Q7L0J3,Q9BT78,Q9NR31,O00461,P49755,P61020,Q92542,O15400,O60499,O95249,P51790 37 +Lysosomal lumen 0.7549448521267832 4.271068046919766 1.945390329027852e-05 0.0175665552892419 0.0006066979769823 39 P10619,P50897,Q14108,P07858,P15586,Q13510,P16278,P17900,P11117,Q8IV08,P07602,P61916,Q9UMR5,P54802,Q9UM22,P04062,P38435,Q8NHP8,O14773,P08236,O00584,Q9NZJ7,P04066,P10253,P06865,P06280 26 +Outer membrane 0.5367840175141316 4.26297540674757 2.0172272731988627e-05 0.0182092960855782 0.0006066979769823 95 Q9NS69,Q9NVT9,O96008,P21796,Q9BWH2,Q8N2A8,Q5XKP0,Q8N4H5,Q99720,Q9NX63,P45880,O00264,O43169,P09601,Q13505,Q9Y6C9,Q9GZY8,Q8WY22,Q9Y277,P50402,Q9UKU0,Q6UXV4,O60313,P50416,Q9Y512,Q96TC7,Q8WWV3,Q9HCL2,Q07812,Q5HYI7,Q8IWA4,Q9NQZ5,Q9NZ45,Q9NZJ7,Q07820,Q6NUM9,P57105,Q9NQ88,P30536,Q15388 40 +Intrinsic component of mitochondrial membrane 0.6889180015095573 4.250284824842672 2.134988508983859e-05 0.0192620229917867 0.0006066979769823 50 O60830,O14925,Q99595,O96008,Q9BPX6,Q9Y2R0,Q9BWH2,Q9H9P8,Q5XKP0,Q9H3K2,Q9NX63,O75880,Q13505,Q9GZY8,Q6UXV4,P50416,Q9UG56,Q96NB2,Q9Y512,Q9NWR8,P17152,Q6P4A7,Q9H9B4,Q5HYI7,Q9BUB7,Q8IWA4,P12235,Q8N8Q8,Q8NE86,P57105,Q15388 31 +Integral component of cytoplasmic side of endoplasmic reticulum membrane 0.9340041432376452 3.8824011745223057 0.0001034300557987 0.0899262638392571 0.0018395293193787 2 Q8TCT9 1 +Coated vesicle 0.5102056932122268 3.8787361261151343 0.0001050005758591 0.091227550660124 0.0018395293193787 94 Q9Y3A6,P24390,Q14108,Q13190,P01889,P42892,O43731,Q13445,P51572,P53634,P04439,P20339,Q969X5,Q9Y282,P05067,P49257,P09496,O43752,O15126,Q8N511,Q9BVK6,P10321,Q5VW38,Q15363,Q9NR31,P49755,Q8NDZ4,O95070 28 +Mitochondrial protein containing complex 0.4598880217683991 3.838640192221175 0.000123717569515 0.1065935748576192 0.0020937030336452 164 O60830,P56385,Q9NS69,O14925,Q99623,Q99595,P14406,Q9UDW1,O96008,P20674,P21796,P56378,Q9BPX6,Q96CU9,P00846,P82933,O75438,O43676,P06576,O75306,Q5XKP0,P09669,O75964,Q8N4H5,P00403,Q9NX63,P12236,Q9NX14,Q13505,Q16540,Q7Z7F7,O95168,Q86Y39,Q9Y5J7,Q9BRJ2,Q6UXV4,Q9Y5J9,O95298,P13073,Q9Y5L4,Q9Y512,Q9NWR8,P14927,P24539,Q9P015,Q07812,Q3ZCQ8,Q5HYI7,O60220,O14949,Q8IWA4,P12235,P36542,P09622,O75489,Q9NQ50,Q8IYU8,P03886,P22695,Q8NE86,Q15388,P15954,P10606,Q96IX5,Q9Y4W6,P56134,Q567V2,Q9HCC0,O14548 69 +Intrinsic component of mitochondrial inner membrane 0.7086130067424384 3.8378716073996832 0.0001241053389866 0.1069091611742109 0.0020937030336452 34 O60830,Q5HYI7,Q9UG56,O14925,O75880,Q99595,Q13505,Q9NWR8,Q8N8Q8,Q9Y2R0,Q9H9P8,Q6P4A7,Q5XKP0,Q9H3K2,Q6UXV4,Q9NX63 16 +Azurophil granule 0.5362618864782353 3.781197905560321 0.000156075535538 0.1325487023853153 0.0024099120826305 75 P10619,Q13277,P15586,Q9BTY2,Q9NQX7,P27105,P16278,P17900,O95721,P53634,O15260,O75629,P07602,P11279,P61916,P51809,O95298,P50995,Q9H0U3,P08236,O00584,Q92542,O15400,Q07065,Q9NZJ7,P04066,P10253,O43681,P06865,P42785,P06280 31 +Vacuolar membrane 0.4618682117960315 3.7624876567967886 0.0001682316136355 0.1421035659133313 0.0025124426233112 138 P10619,Q14108,P42892,Q9NQX7,P27105,P61019,O15118,O95721,Q9H2V7,O43633,O15260,P11117,Q8IV08,P07602,P51798,P11279,O95772,Q14849,P51809,Q8IY95,Q9BXS4,P09496,Q9Y6I9,Q9Y487,O95298,Q8N511,P04062,Q86YV9,Q93050,Q16625,Q9H0U3,Q9UIQ6,O75503,Q8WTV0,P13473,Q8TCT8,Q92542,Q07065,O15400,Q9NZJ7,Q9H0B6,P10253,Q9HC07,P22413,Q05639,P42785,P51790 47 +Histone pre mrna 3 end processing complex 0.9073690440958866 3.7562671240357046 0.0001724666057856 0.1454075823032196 0.0025199614588416 2 P67809 1 +Endoplasmic reticulum golgi intermediate compartment 0.6114069047300584 3.753665519877465 0.0001742673676257 0.1468086294442516 0.0025199614588416 53 Q9Y3A6,P24390,O15498,Q13190,P80303,P51572,Q13445,P61019,P53634,O15260,Q969X5,Q9Y282,Q8N511,Q10472,Q9BVK6,P33908,Q8N3R9,Q15363,P49755,O95070,O15258 21 +Endoplasmic reticulum golgi intermediate compartment membrane 0.7502524374950748 3.713128839739843 0.0002047126039901 0.1701516233324111 0.0028493870543694 27 Q9Y3A6,P24390,Q8N511,P53634,O15260,Q10472,O15498,Q13190,Q9BVK6,P49755,Q969X5,Q9Y282,Q15363,Q13445,O95070,P51572,P61019 17 +Intrinsic component of plasma membrane 0.5192035044585323 3.711012396833968 0.0002064319929619 0.1714507167842515 0.0028493870543694 89 P05023,Q9BQT9,O15498,P05026,O60637,P01889,Q15375,P27105,O43657,O15031,P51572,P16615,O95864,O15118,O00264,P04439,P36551,P35613,P05067,Q9Y289,P11279,Q8TAB3,P0DP25,P53985,Q02978,P17152,P10321,Q08722,Q9H0U3,Q9UIQ6,Q96QD8,Q8WTV0,O43464,Q15758,P10586,Q8N2K0,P12235,Q9NR28,Q99808,Q92542,Q99805,P30825,P22413,P78536,O96005,P51790 46 +Gamma secretase complex 0.8949393311630665 3.696723493273363 0.000218399993987 0.1804370957003422 0.0029695879779439 2 P49755 1 +Golgi apparatus subcompartment 0.4818711700670753 3.662858630590687 0.0002494162025963 0.2032756354478505 0.0033414435377243 96 Q9NX62,O14828,P51572,Q9H4A5,Q5T9L3,P04439,P53365,Q8WVQ1,Q9H4A6,Q8TBA6,P05067,Q9NPR9,Q4J6C6,P51809,P09496,O43752,O15126,Q10472,P04062,P98194,Q15363,P0CG08,O00461,Q9BZG1,Q8NBZ7,O60499,Q9HC07,Q10713,O95249,O15127 30 +Golgi cisterna 0.7313200622902628 3.588927977085724 0.0003320405497644 0.2610604574948851 0.0042012352893805 27 Q9H4A5,Q10472,P04439,Q8WVQ1,Q9H4A6,P98194,Q8TBA6,Q15363,Q9BZG1,Q10713,O95249,P0CG08,P51572,O00461,Q8NBZ7 15 +Endoplasmic reticulum tubular network membrane 0.8706717963894652 3.5791857307449377 0.0003446664556474 0.269514037771883 0.0042431235283085 2 Q9NQC3 1 +Endoplasmic reticulum lumen 0.5279226989769608 3.560702163810791 0.0003698644215215 0.2860974536286133 0.0044335064211331 69 Q02818,O43852,Q9BS26,Q9BTY2,O95881,P13674,Q9NWM8,O75718,P53634,Q6P179,Q15293,P05067,Q9Y680,Q13438,Q9NZ08,Q32P28,P10909,O76024,O00584,Q14257,Q07065,O15460,Q9BTV4,Q5JRA6,O43681,P78536,P07942,P27361 28 +Cis golgi network membrane 0.8641609943770356 3.547356088453348 0.0003891182724984 0.2985149792067778 0.0045447018749496 2 Q9NPR9 1 +Copii coated er to golgi transport vesicle 0.6785130498159417 3.5285822443355697 0.0004177921000827 0.3166090164879703 0.0046988716441405 32 Q9Y3A6,Q13190,P01889,O15027,Q13445,P53634,P04439,Q969X5,Q9Y282,P05067,Q5VYK3,P49257,O75340,Q9BVK6,P10321,Q15363,Q9NR31,Q12907,P49755,O95070 20 +Secretory granule membrane 0.5115347378756422 3.485242944345749 0.0004916903981153 0.3611209420627917 0.0053324994367035 80 Q13277,P01889,P30519,Q969Q5,Q9NQX7,P27105,O95721,O00264,O15260,Q96JJ7,P35613,P07602,P11279,P51809,O15126,O95298,P10321,Q93050,Q15363,Q08722,Q9H0U3,P13473,P49755,P61020,Q07065,Q92542,Q9NZJ7,P10253,P20073,P42785 30 +Vesicle membrane 0.409327540112704 3.4743352398904856 0.000512120763727 0.3729076869766013 0.0053810565524369 282 Q15907,Q13277,Q9BRG1,P24390,Q14108,O15498,Q13190,P01889,P42892,P30519,O43731,Q969Q5,Q9NQX7,P27105,O14828,Q96L92,O15118,Q5T9L3,O95721,O43633,O00264,P04439,O15260,Q96JJ7,P35613,P20339,Q8IV08,P07602,P11279,P49257,O95772,P51809,Q14849,Q9BXS4,O60749,P09496,O43752,Q9Y287,O15126,Q9Y487,O95298,P0DP25,Q8N511,O43760,P10321,Q86YV9,Q93050,Q15363,Q08722,Q9H0U3,Q7L0J3,Q9UIQ6,Q9Y5X3,Q9NR31,Q8WTV0,P13473,O00461,Q9BZG1,Q8TCT8,P49755,P61020,Q07065,Q92542,Q9NZJ7,O15400,Q99805,Q8NDZ4,O60499,Q9H223,P10253,Q9HC07,P20073,P42785,O15127,P51790 75 +Golgi stack 0.6470639166861099 3.437603025629693 0.0005868874093748 0.4142202318590351 0.0059406047771165 36 Q9H4A5,Q10472,P04439,Q8WVQ1,Q9H4A6,P98194,Q8TBA6,Q15363,Q9BZG1,Q10713,O95249,P0CG08,P51572,O00461,Q8NBZ7 15 +Endolysosome lumen 0.8360461675051811 3.4084373572705053 0.0006533608439889 0.448661465122161 0.0062147476784024 2 P07858 1 +Golgi cisterna membrane 0.7425748337560051 3.3690892675257524 0.0007541699948014 0.4970719050142129 0.0067357731888642 20 Q9H4A5,Q10472,Q8WVQ1,Q9H4A6,P98194,Q15363,Q10713,P51572,O00461,Q8NBZ7 10 +Bcl 2 family protein complex 0.8245042912104191 3.350700672962252 0.0008060738146637 0.5203167878757673 0.0071294489821235 2 Q07820 1 +Intrinsic component of vacuolar membrane 0.8215448357502237 3.335828848130437 0.0008504550412573 0.5393396063620721 0.0073787099293852 2 O15118 1 +Secretory vesicle 0.4004166986888606 3.307001940643097 0.0009430023872281 0.5766180213322689 0.0081044827808 281 Q15907,Q13277,P50897,P30519,O00571,Q13510,P45880,P53634,O00264,O15260,O75629,P07602,P11279,P51809,O43752,P14174,Q9Y487,O95298,P50995,Q93050,Q15363,Q9H0U3,Q9BT78,P13473,P61421,P09622,O43242,P06865,P42785,P10619,P07858,P42892,P15586,Q9BTY2,Q9NQX7,P17900,P35613,P05067,O43760,Q8NBX0,O00584,P61020,Q07065,O60499,P04066,P06280,O00231,Q92905,Q969Q5,O75874,P27105,Q96JJ7,P20339,P61916,Q9NUQ9,P09496,Q9BVK6,P10909,Q08722,Q7L0J3,P49755,Q92542,Q9NZJ7,P10253,P20073,P51790,P01889,P16278,O95721,Q92520,Q9GZY8,Q8WVQ1,Q9Y6I9,Q6UXV4,O15126,P0DP25,P10321,P08236,Q9UQB8,O15400,O43681 81 +Schmidt lanterman incisure 0.8150340337377944 3.30301288390428 0.000956519929975 0.5818046758473735 0.0081438285626846 2 Q8N3R9 1 +Endoplasmic reticulum protein containing complex 0.5229570049355011 3.29889303331784 0.0009706689109405 0.5871656380171633 0.0081877720172856 64 Q9P0I2,Q9UBV2,Q9GZP9,Q8TCJ2,P49069,O15269,P13674,P04439,Q15041,Q9NPA0,Q9BUN8,Q13438,P51571,P67812,Q5J8M3,Q8TCT9,P61009,Q9H0U3,P46977,Q53GQ0,Q9Y5M8,O43681,O43292,P04843 24 +Endocytic vesicle 0.4680825160592886 3.237717073909218 0.0012049023596465 0.6665718474666887 0.009628649558228 92 Q15907,Q14108,P01889,Q969Q5,Q5T9L3,P04439,P20339,P11279,P51809,P09496,O43752,Q9Y487,Q14C86,P10321,P50995,Q93050,P08670,Q16625,Q8WTV0,P13473,O00461,Q9BZG1,P61020,O15400,Q9H223,P51790 26 +Azurophil granule membrane 0.6838922162880312 3.2245655773283066 0.0012616395769908 0.683388338942591 0.0099943796055538 26 O60784,Q9NQX7,P27105,O95721,O75131,O15260,P07602,P11279,P51809,Q8NF37,O95298,Q6IAA8,Q9H0U3,P13473,P51148,Q92542,Q07065,Q9NZJ7,P10253,P42785 20 +Exocytic vesicle 0.5865461959765285 3.2145623938309287 0.0013064351911962 0.6960647434146106 0.0102600211998254 46 Q15907,Q13277,P50897,Q92905,Q9GZY8,P20339,P05067,P11279,P09496,O43752,O15126,P0DP25,O43760,Q9BVK6,Q7L0J3,Q9BT78,P61020,O15400,Q92542,O60499,P51790 21 +Respirasome 0.5833973239348027 3.1874079635795467 0.0014355413665338 0.7298337500907115 0.0110828659738337 46 O43674,Q96CU9,Q9UDW1,P20674,Q6DKK2,P14406,O75438,O43676,O75306,P09669,P00403,Q9NX14,P21912,O95168,Q86Y39,O95298,P13073,P14927,O14949,O75489,P03886,P22695,P15954,P10606,Q13423,O14548 26 +Vacuolar proton transporting v type atpase v0 domain 0.8520060445089999 3.1368919124386103 0.0017074906239618 0.7892016929412071 0.0120570342450706 3 Q9Y487 1 +Proton transporting v type atpase v0 domain 0.8520060445089999 3.1368919124386103 0.0017074906239618 0.7892016929412071 0.0120570342450706 3 Q9Y487 1 +Transport vesicle membrane 0.5764642456454625 3.127335923600362 0.0017639824926682 0.7997937250547213 0.0122670843574108 46 Q15907,Q13190,P01889,Q86Y82,O15027,P04439,P20339,P49257,P51809,P09496,O43752,O15126,P0DP25,O43760,O75340,P10321,Q15363,Q7L0J3,O76024,Q9NR31,Q9Y6B6,P49755,P61020,O60499,Q9NV96 25 +Astrocyte projection 0.7786327315773927 3.1170103697927662 0.0018269514575162 0.8109748072698459 0.01242054311789 2 P05067 1 +Proton transporting two sector atpase complex 0.685447073486809 3.112902747289251 0.0018525705342462 0.8153433222779577 0.0125014204199877 23 P36542,Q8N511,P24539,P61421,P56378,Q93050,P00846,P56134,P06576,Q96IX5,O75964,Q9Y487 12 +Pigment granule 0.5077124737550801 3.0680353296466496 0.0021547114206792 0.8598525132183519 0.0138552497855771 62 Q13277,P05023,P57088,O43852,P07858,P27105,P50991,P61019,P35613,P20339,P51151,P11279,Q92820,P54709,P07237,P62258,P50995,Q93050,O14773,Q15758,P55209,P49755,P27824,P61020,Q92542,P51148,P04843,P51149 28 +Mhc class i protein complex 0.8374777975133186 3.0673504806201164 0.0021596547415498 0.8604835878439302 0.0138552497855771 3 P10321,P01889 2 +Mhc protein complex 0.8374777975133186 3.0673504806201164 0.0021596547415498 0.8604835878439302 0.0138552497855771 3 P10321,P01889 2 +Chromaffin granule 0.8338318942989296 3.0498036849886767 0.0022899099369253 0.876127207240234 0.0145881675002726 3 P10909 1 +Ciliary rootlet 0.7632435631843772 3.037051234344821 0.0023890484526831 0.8868484353256699 0.014897081225068 2 P05067 1 +Snare complex 0.7302117032900262 3.0351940100403967 0.0024038100330241 0.8883634956360089 0.014897081225068 18 Q9P2W9,Q13277,O95721,O15400,O15498,Q13190,O60499,O95249,Q12981,O43752 10 +Hrd1p ubiquitin ligase erad l complex 0.8957887078181543 3.016685816134924 0.0025555453558772 0.9028094390662008 0.0156248444241888 4 Q9BUN8,Q9UBV2 2 +Endosome 0.3942581714471026 3.014586219813474 0.0025733005875561 0.9043728290409224 0.0156285122350908 231 Q92544,Q15907,Q9BRG1,Q9GZP9,Q14108,Q96PU5,P07858,O15498,P01889,P42892,Q567U6,Q969Q5,O14828,Q96L92,Q13510,Q9NX40,O15118,Q5T9L3,O43633,P04439,P35613,Q99538,P20339,Q9H4A6,Q8IV08,P05067,P07602,P11279,Q9BUN8,Q2M389,O95772,Q14849,Q8IY95,P51809,O60749,P09496,O43752,Q9Y287,O15126,Q9Y487,Q14C86,P10321,Q5VW38,P31751,P24941,Q93050,Q86YV9,Q9Y5X3,Q9UIQ6,O14773,O00461,Q8TCT8,P61020,Q92542,O15400,Q9NZJ7,Q99805,Q13501,Q9H223,Q9HC07,O15127,P51790 62 +Cis golgi network 0.7442571616523384 3.0022638782266085 0.0026797977376562 0.913236797720963 0.0160611561776634 17 P49755,Q9Y3A6,P24390,P98194,O43731,O95249,Q9NPR9,O00461 8 +Secondary lysosome 0.8217880402605064 2.991565214437171 0.0027755124907649 0.920500720141703 0.0161098362299908 3 Q13501,P11279 2 +Autolysosome 0.8217880402605064 2.991565214437171 0.0027755124907649 0.920500720141703 0.0161098362299908 3 Q13501,P11279 2 +Compact myelin 0.8152753108347951 2.959895718249126 0.0030774319207513 0.9396662242269102 0.0176323300616635 3 Q8N3R9,Q9NR77 2 +Tim22 mitochondrial import inner membrane insertion complex 0.7422314294169905 2.926567604912662 0.0034272500882246 0.9561766022550152 0.0191547535605684 2 Q9Y5J7 1 +Synaptic vesicle membrane 0.7073036272758965 2.8968873054007314 0.0037688511285089 0.967932419463862 0.0206832733618777 18 O43760,P61020,P20339,O60499,Q7L0J3,P09496,O43752,O15126,P0DP25 9 +Mitochondrion 0.3401289428249739 2.8718764999960285 0.0040804239728138 0.9758837874409634 0.0219529820618118 660 O60830,Q9NS69,Q99595,Q16740,Q9UDW1,P21796,P20674,Q9Y2R0,Q9UDX5,Q9P0J1,P00846,Q9H9P8,Q13011,O43676,Q69YU5,P06576,O75964,Q8N4H5,P00403,P13674,Q70HW3,Q9H2D1,P45880,Q9NR77,O00264,P09601,P22830,Q9UBX3,Q16540,Q8WY22,Q04837,Q9NPH0,O00116,O43615,Q14849,Q7Z7F7,Q96EY8,P83111,O95298,P50416,Q8N2F6,Q9Y5L4,Q9Y512,Q9NPL8,Q96TC7,Q96A26,Q8WWV3,Q96JX3,Q07812,Q6P4A7,O95831,Q5HYI7,P28288,O14949,Q9NVH6,P09622,Q9Y619,Q9Y3B8,O95202,P03886,P22695,P57105,Q3SXM5,P10606,Q9NQ88,P30536,Q8IXJ6,P15954,Q13423,Q9H3H1,Q567V2,Q5T9A4,Q9HCC0,Q96AG4,P56385,O14925,Q9NVT9,Q9BWD1,P14406,Q9BSK2,O96008,Q9Y2S7,Q6DKK2,P56378,Q9H3P7,P06493,O43772,P52789,Q9P0S9,Q9H061,Q9NUJ1,Q9UL15,Q9H2V7,Q8N183,Q9Y2C4,O43169,Q13505,P12236,P35613,Q6NUK1,Q9NX14,Q5JRX3,Q9Y277,P48735,P18031,O95168,Q86Y39,Q9UKU0,Q9BRJ2,Q9Y5J9,P13073,Q02978,Q96NB2,Q8TAE8,Q8NI60,P24539,Q9UMX5,Q8NBX0,Q9HCL2,O43464,O60220,Q9NR28,O00584,Q8N8Q8,Q9H0B6,Q10713,O43292,Q9H6K4,Q15388,Q96CU9,Q9BPX6,P82933,Q8N2A8,O75874,P27105,Q5XKP0,Q9Y2W6,Q9H3K2,P48723,Q9NX63,Q9Y6C9,Q9BQT8,Q9NUQ9,O75208,Q9UG56,Q9H773,P10909,Q3ZCQ8,Q8IWA4,Q15165,P36542,Q92542,Q9NZJ7,Q9NQ50,P00374,Q9NVI7,Q96BR5,Q8IYU8,O15498,Q9BWH2,Q86Y07,O75438,O75306,P09669,P51572,P31749,O75880,P16435,P36551,Q9GZY8,Q9H4A6,O95674,Q9Y5J7,Q9UHV9,Q6UXV4,P0DP25,O60313,Q08J23,Q9BXK5,Q9NWR8,P17152,Q9BUB7,Q8N5M1,Q9NQZ5,Q96EK5,Q9NZ45,O75489,Q07820,Q13501,Q9H936,Q9BW92,P53701,P56134,Q12981,Q96IX5 195 +Derlin 1 retrotranslocation complex 0.8600010839804815 2.8542099733657817 0.0043144005298623 0.980530809739556 0.0228512725738637 4 Q9BUN8,Q8TCT9 2 +Outer mitochondrial membrane protein complex 0.7349386404469471 2.8403408238225567 0.004506535713167 0.9836696935965727 0.0236338206899351 16 Q9NS69,Q9Y512,Q5XKP0,Q13505,Q5HYI7,Q15388,Q8IWA4,Q6UXV4,Q8N4H5,Q9NX63 10 +Golgi associated vesicle 0.5868550576533696 2.839810517247045 0.0045140338090545 0.9837813639196636 0.0236338206899351 32 Q8TCT8,Q8N511,P24390,Q9BVK6,P05067,O43731,Q15363,P09496,Q9Y287 9 +Voltage gated calcium channel complex 0.7209233501035848 2.812950689476744 0.0049089178307986 0.9887009496617256 0.0246127660071515 2 P62942 1 +Zymogen granule membrane 0.84868226236304 2.802135571291532 0.0050765535421668 0.9903086256202588 0.0251344580267065 4 Q15363,P49755,O15126 3 +Intrinsic component of golgi membrane 0.8403323738948743 2.7913066713716868 0.0052495707782849 0.9917286351676612 0.0258505890757706 10 Q8TB61,Q969X5,Q9Y282,O43505,L0R6Q1,O95070,Q6ZRP7,O15258 8 +Intrinsic component of postsynaptic density membrane 0.7794320158529244 2.78333494294157 0.0053803230588851 0.9926621364755862 0.0263520124013137 3 Q9BQT9 1 +Cytochrome complex 0.705162295139826 2.7714960775596413 0.0055799344581317 0.9938883321205456 0.0270389377199895 17 P13073,P14927,P14406,P22695,Q9UDW1,P20674,P15954,P10606,P09669,O14949,P00403 11 +Cell body membrane 0.7046463450725107 2.725067608880245 0.0064288321190135 0.997192814497234 0.0305823210745618 2 P55011 1 +Secretory granule 0.3730187332850694 2.7236703688000907 0.0064560907491892 0.99726210672106 0.0305823210745618 249 P10619,Q13277,P07858,O00231,P01889,P42892,P30519,P15586,Q9BTY2,O00571,Q9NQX7,Q969Q5,O75874,P27105,Q13510,P17900,P16278,O95721,P45880,P53634,O00264,O15260,Q96JJ7,P35613,Q92520,Q8WVQ1,O75629,P05067,P07602,P11279,P61916,P51809,Q9NUQ9,Q9Y6I9,P14174,Q6UXV4,Q9Y487,O95298,O15126,P10321,Q8NBX0,P50995,Q93050,Q15363,Q08722,P10909,Q9H0U3,P08236,P13473,Q9UQB8,O00584,P61020,P09622,Q07065,P49755,Q92542,Q9NZJ7,O15400,P04066,O43242,P10253,P20073,O43681,P06865,P42785,P51790,P06280 67 +Micos complex 0.8315121995589085 2.722499108724532 0.0064790208204066 0.9973190707450856 0.0305823210745618 4 Q5XKP0,Q9NX63 2 +Mitochondrial intermembrane space protein transporter complex 0.8291382884216717 2.711427233937351 0.0066994243685443 0.9978096879370978 0.0314596680399168 4 Q9Y5J7,O60220,Q9Y5J9 3 +Escrt i complex 0.7010949985202762 2.705765687437289 0.0068147110701954 0.9980294684161256 0.0316744989027963 2 Q9H9H4 1 +Prefoldin complex 0.8259491564363725 2.6965295523715587 0.007006618014308 0.998347549166406 0.0324011624925614 4 O15212 1 +Paranodal junction 0.6966558153299833 2.6815736234843977 0.0073276788353549 0.9987692032762032 0.0332115194975538 2 Q8IXJ6 1 +Presynapse 0.4071522398254502 2.6755203373512058 0.0074613346138134 0.998911289223075 0.0336498803622974 97 P07196,Q15907,Q13277,P50897,Q92905,O95721,Q9GZY8,P20339,P05067,P11279,P09496,O43752,O15126,P0DP25,O43760,Q9BVK6,Q7L0J3,Q9BT78,Q9UQB8,P61421,Q99808,P61020,Q92542,O15400,O60499,P51790 26 +Sodium potassium exchanging atpase complex 0.7572528123149757 2.6721219659932376 0.0075373247400838 0.9989846390766354 0.0336593276383155 3 P05026,P05023 2 +Cation transporting atpase complex 0.7572528123149757 2.6721219659932376 0.0075373247400838 0.9989846390766354 0.0336593276383155 3 P05026,P05023 2 +Organelle envelope lumen 0.5355595631403995 2.667802309552631 0.0076349167528961 0.99907164566693 0.0339288251799435 43 Q9NR28,O14925,O00584,P36551,Q9Y3B8,Q9H4A6,Q9BPX6,P05067,O95831,Q96BR5,Q9Y5J7,Q8IYU8,O43464,O60220,Q9Y5J9 15 +Side of membrane 0.4414784630329132 2.6556697367192386 0.0079151089323556 0.9992822234963344 0.0348315664686122 81 P10619,P00813,Q8TCT8,Q9NR28,P31749,P07858,O43464,P20339,Q8TCT9,P42892,P01889,P08183,P51572,Q9Y5X3,O96005,P17900,Q05639,P51790 18 +Platelet dense tubular network 0.6916247410476515 2.6540687744849993 0.0079527616086403 0.99930661712679 0.0348315664686122 2 P16615 1 +Platelet dense tubular network membrane 0.6916247410476515 2.6540687744849993 0.0079527616086403 0.99930661712679 0.0348315664686122 2 P16615 1 +Cd40 receptor complex 0.7532092070416898 2.651681693962869 0.0080092007512708 0.9993416395206174 0.0349109181072141 3 O43464 1 +Organelle membrane contact site 0.6435604986117267 2.613242865994905 0.0089687543778664 0.9997273701543924 0.0381975622464049 19 Q96TC7,Q96N66,O96008,Q9Y320,Q96JX3,O43865,Q96S66,O95772,Q14849,Q5XKP0,Q15388,P51572,Q9NTJ5 13 +Endocytic vesicle membrane 0.5140330867377131 2.6021814528880256 0.0092632826202472 0.9997920430060944 0.0392504672885824 47 Q15907,Q5T9L3,Q14108,P04439,P10321,P01889,P20339,Q93050,P11279,P51809,Q8WTV0,P13473,Q9BZG1,Q9Y487 14 +Early endosome 0.3970442534909139 2.5591988896372673 0.0104913699130615 0.99993281951788 0.0437302620411641 109 Q92544,Q9GZP9,Q96C92,Q86Y82,P01889,Q567U6,O60784,Q96L92,Q13510,Q5T9L3,P04439,P20339,Q9UNH7,Q8IV08,P05067,Q9BUN8,Q5VYK3,P18031,O60749,Q9Y2I1,O43752,P10321,Q5VW38,P31751,Q86YV9,Q9Y5X3,Q9UIQ6,P61421,P51148,P61020,Q92542,O15400,Q9H223,Q9HC07,Q9P253,P27361,P51790 37 +Neurofibrillary tangle 0.734902054713813 2.558497957009526 0.0105125437837705 0.9999341164599922 0.0437302620411641 3 P10909 1 +Er to golgi transport vesicle membrane 0.6123122312445659 2.554033860467377 0.0106482900801005 0.9999418572412448 0.0438940826378807 21 P49755,O75340,P04439,Q13190,P10321,P01889,Q15363,P49257,O15027,Q9NR31 10 +Zymogen granule 0.843979921155829 2.5404489196803217 0.0110710264154523 0.999960608091486 0.0453864107527756 5 Q15363,P49755,O15126 3 +Golgi associated vesicle membrane 0.6091366325775965 2.532203037541842 0.0113348336131215 0.9999691076313864 0.0460983634890793 21 Q8TCT8,Q8N511,P24390,Q15363,O43731,Q9Y287 6 +Phagocytic vesicle membrane 0.5800915649145834 2.5272127656215733 0.0114971827036336 0.9999734002654708 0.0463448382434082 27 Q15907,P04439,P10321,P01889,P20339,P61421,Q93050,P11279,P51809,P13473,Q9BZG1,Q9Y487 12 +Platelet dense granule 0.727098629582369 2.5184566908920867 0.0117870378332598 0.9999796367296232 0.0473039271634349 3 Q92520 1 +Endosome membrane 0.3789321250336134 2.5047345027109893 0.0122543340944729 0.9999867652446068 0.0487689612922951 139 Q15907,Q9BRG1,Q14108,P01889,P42892,Q96L92,O14828,O15118,Q5T9L3,O43633,P04439,P20339,Q8IV08,P11279,O95772,Q14849,P51809,Q9BXS4,O60749,P09496,Q9Y287,O15126,Q9Y487,P10321,Q86YV9,Q93050,Q9Y5X3,P13473,O00461,Q8TCT8,P61020,Q92542,O15400,Q99805,Q9H223,Q9HC07,O15127,P51790 38 +Uniplex complex 0.7799822327509573 2.478754542188054 0.0131842001170032 0.9999943884614064 0.0504655727167646 4 Q8IYU8,Q9BPX6,Q9NWR8 3 +Filtration diaphragm 0.6593666765315229 2.475490005391212 0.0133053485739882 0.999994982271708 0.0507162031418547 2 P46940 1 +Proton transporting atp synthase complex 0.7319711604794042 2.464508336440077 0.0137201371889703 0.9999965790139422 0.0518632571749045 12 P36542,P24539,P56378,P00846,P56134,P06576,Q96IX5,O75964 8 +Golgi medial cisterna 0.7766025352772982 2.462515598000958 0.0137966171647112 0.9999968123511452 0.0519368522192229 4 O95249,P04439 2 +Phagocytic vesicle 0.502359805866423 2.4595378425463506 0.0139116030459718 0.9999971335915494 0.0521541990735816 46 Q15907,P51790,P04439,P10321,P01889,P20339,P13473,P50995,Q93050,P08670,P11279,P51809,O43752,Q9BZG1,Q9Y487 15 +Wnt signalosome 0.7146240378922406 2.454044244229475 0.0141259599957941 0.9999976486158524 0.0527407768695428 3 P25054,P49841 2 +Respiratory chain complex iv 0.7410615322338159 2.437952553395042 0.0147707125749352 0.9999987043356102 0.0539249238543748 11 P13073,P14406,P22695,P20674,P15954,P09669,P00403 7 +Intrinsic component of peroxisomal membrane 0.8209209022683268 2.4358735390459048 0.0148558771983202 0.9999988024568728 0.0539249238543748 5 Q9Y5Y5 1 +Coated vesicle membrane 0.4586459612078058 2.428878669415114 0.0151455998707843 0.9999990839504702 0.0545361323410456 58 Q8N511,P24390,Q14108,P49755,P04439,Q8NDZ4,Q13190,P10321,P01889,P20339,O43731,Q15363,P49257,Q9NR31,P09496 15 +Intrinsic component of mitochondrial outer membrane 0.7246140273386076 2.424826117993495 0.0153157204823497 0.9999992173437332 0.0549315801551993 12 P50416,Q9GZY8,P57105,Q9BWH2,Q15388,Q8IWA4 6 +Microbody membrane 0.5380719461449119 2.3967155731373557 0.016542759295558 0.9999997486700424 0.0586398977363944 31 Q9Y5Y5,P51648,Q9NR77,Q15067,Q5T8D3,O43808,O00116,P40855,Q9UKU0,O75381 10 +Lumenal side of membrane 0.7590820495951695 2.389129690942769 0.0168883395186754 0.999999817529019 0.0591741434673588 10 P10619,Q8TCT8,P10321,P01889,Q8TCT9,P51572 6 +Microtubule organizing center attachment site 0.7004144464180057 2.3800671200728885 0.0173094848695969 0.9999998764984904 0.0601867966267282 3 Q9UH99,O94901 2 +Copi coated vesicle membrane 0.6997055731205328 2.3662247586804046 0.0179705310070257 0.9999999330981562 0.0615456907797008 13 O43731,Q8N511,P24390 3 +Proton transporting two sector atpase complex proton transporting domain 0.7452147964757927 2.318554528823489 0.0204192030657277 0.9999999931185573 0.0683893161502867 10 P24539,Q93050,P00846,P56134,O75964,Q9Y487,P61421 7 +Respiratory chain complex iii 0.7954841956314134 2.31402051954739 0.0206665965977899 0.9999999945330228 0.0689643571450058 8 Q9UDW1,O14949 2 +Hulc complex 0.6300680674755897 2.309917507110105 0.0208927216240131 0.9999999955701996 0.0692118887253671 2 Q5VTR2 1 +Intrinsic component of synaptic vesicle membrane 0.7020425904271128 2.3019395803055684 0.021338579719607 0.9999999970746444 0.0699260651962663 12 P61020,P20339,O60499,Q7L0J3,O43752 5 +Dendrite membrane 0.6847261951602364 2.2976392067962528 0.0215823322486685 0.9999999976685566 0.0700640367849781 3 Q14168 1 +Tim23 mitochondrial import inner membrane translocase complex 0.8398473658101049 2.2971290362964507 0.0216114098096364 0.999999997730832 0.0700640367849781 6 O60830,O14925,Q99595 3 +Early endosome membrane 0.4618785447775301 2.2818614289768977 0.0224975226741184 0.9999999990060224 0.0721663491412742 52 P51790,Q5T9L3,P61020,O15400,P10321,P01889,P20339,Q8IV08,Q86YV9,Q9H223,Q9HC07,Q9Y5X3,Q96L92,O60749 14 +Proton transporting v type atpase complex 0.7089981368898333 2.2675692750397674 0.0233554721384063 0.9999999995533464 0.0741353140003073 11 Q8N511,Q9Y487 2 +Phospholipid translocating atpase complex 0.6197099733649063 2.250606785511459 0.0244104532726479 0.999999999833136 0.0764189791456434 2 Q9NV96 1 +Transporter complex 0.4208613346906808 2.2417061501819844 0.0249803701377857 0.9999999999020126 0.0766232902206155 66 Q99996,P05023,O43674,Q9UDW1,P05026,Q96CU9,Q9BPX6,O75438,O43676,O75306,Q9NX14,Q9C0H2,P51798,P54709,Q9Y5J7,O95168,Q86Y39,Q9Y5J9,P0DP25,O95298,Q9Y6M9,Q9Y5L4,Q9NWR8,P14927,Q4KMQ2,O60220,O14949,Q8N2K0,P56556,O75489,P03886,Q8NE86,P22695,Q9NV96,Q96S66,P51970,Q8IYU8,O75381 38 +Cell surface 0.4016659749934153 2.222250559735717 0.0262663773197255 0.9999999999705564 0.0797622324609 88 P00813,Q9BQT9,P07858,P01889,P42892,P06576,O15031,P04439,Q96JJ7,P05067,P14174,O75298,P10321,Q8TCT9,P10909,Q08722,Q8WTV0,P22413,O96005,P08183,P51790,O15258 22 +Rough endoplasmic reticulum 0.492082288543319 2.186105089967896 0.0288079176976459 0.9999999999972774 0.0849320809791437 37 Q5BJF2,P51571,Q07065,Q9Y5M8,Q15041,Q8TCT9,Q99442,P05067,Q9H9S5,Q96A33,Q9UQB8 11 +Copi coated vesicle 0.6535178132102217 2.1825532588850547 0.0290687250982157 0.9999999999978684 0.0854245437563696 14 O43731,Q8N511,P24390 3 +Golgi lumen 0.7649009651349707 2.176370445392827 0.0295275718785612 0.9999999999986142 0.0864939484931488 5 O00461,P05067 2 +Mitochondria associated endoplasmic reticulum membrane 0.7167981988571143 2.1721461646009663 0.0298446398363727 0.999999999998971 0.0869209901141537 10 Q96N66,Q9Y320,O96008,Q96JX3,Q96S66,O43865,Q15388,P51572 8 +Lumenal side of endoplasmic reticulum membrane 0.7653466504005217 2.170624152492501 0.0299595948362725 0.9999999999990764 0.0869209901141537 8 Q8TCT8,P10321,P01889,Q8TCT9,P51572 5 +Sperm connecting piece 0.6052086416099494 2.1668922585042196 0.0302430703859541 0.9999999999992922 0.0871880921569755 2 P47756 1 +Ragulator complex 0.6565680089746124 2.147710527046478 0.0317367585708372 0.9999999999998264 0.0897894008013438 3 Q9UHA4 1 +Trans golgi network membrane 0.5223057000055885 2.1207494398239333 0.0339428935630379 0.9999999999999782 0.0954381976417516 28 Q9H4A5,Q9NX62,P53365,O60499,P05067,Q9HC07,P40616,O14828,P09496,O43752,O15127,O15126 12 +Postsynaptic recycling endosome 0.6497927767910081 2.111257386100806 0.03475019470235 0.99999999999999 0.0974074688425874 3 Q4V328,Q86Y82 2 +Anchored component of synaptic vesicle membrane 0.7494517511564855 2.1034461721500075 0.0354267859367347 0.9999999999999948 0.0989993926023477 5 P61020 1 +Phagophore assembly site membrane 0.7023985786200719 2.098037681492804 0.0359018168238471 0.9999999999999966 0.1000200462584856 4 Q7Z3C6,Q9H0U4,P51149 3 +Tubular endosome 0.6976136258884662 2.0740149706499813 0.0380779205221233 0.9999999999999996 0.1057591024257754 4 Q9Y5X3 1 +Mib complex 0.6926184467220928 2.045681830340152 0.0407876845369996 1.0 0.111920423533755 10 Q5XKP0,Q13505,Q5HYI7,Q6UXV4,Q9NX63 5 +Microbody 0.4181805781620172 2.0345457965145677 0.0418965960787567 1.0 0.1142748473884652 60 Q9Y5Y5,P51648,Q9NR77,Q15067,Q5T8D3,Q9GZY8,Q9BQG2,O43808,P08670,O14734,O15254,O00116,Q13011,O75874,P40855,P48735,Q9UKU0,O75381 18 +Mitochondrial crista 0.6837008761427796 2.003814469140254 0.0450899383064731 1.0 0.1208145111682265 4 O60313,Q9BUB7 2 +Specific granule membrane 0.5366697542180763 1.995882059346404 0.0459467619576123 1.0 0.1227492672826536 20 Q07065,O00264,P30519,Q08722,P27105 5 +Intrinsic component of postsynaptic specialization membrane 0.6799312908368311 1.984704563700296 0.0471773507763682 1.0 0.1249376934804401 4 Q9BQT9 1 +Trans golgi network 0.3931332633676214 1.974304124577146 0.0483471721969472 1.0 0.1265640053776407 68 Q9H4A5,Q5T9L3,Q9NX62,P04062,P53365,Q9H4A6,P98194,O60499,P05067,Q9HC07,Q9NPR9,Q4J6C6,O14828,P09496,O43752,O15127,O15126 17 +Protein lipid complex 0.7195684804565445 1.960747405589064 0.0499084960826317 1.0 0.1288006796920042 5 Q9UHG3 1 +Neurofilament 0.6692127391219038 1.93016110338608 0.0535868793664162 1.0 0.1352289393429507 4 P07196 1 +Platelet alpha granule 0.5558858585669108 1.9224003917285628 0.0545553963394325 1.0 0.1365549262085735 18 Q96JJ7,Q8NBX0,P05067,P10909,Q9NUQ9,Q9Y6I9,Q6UXV4 7 +Integral component of synaptic vesicle membrane 0.7341274021622473 1.914912946377243 0.0555036064822807 1.0 0.1381524194135456 7 O60499,Q7L0J3,O76024,O43752,O15126 5 +Membrane microdomain 0.3916413766035507 1.891448555114752 0.0585644921838397 1.0 0.1445860498088834 66 O15118,P50897,P09601,P35613,P21796,P05067,P27105,O14773,Q8WTV0 9 +Emc complex 0.7039501421463458 1.885323465749075 0.0593861799052641 1.0 0.1454322846604722 5 Q9P0I2,Q5J8M3,Q9NPA0 3 +Er ubiquitin ligase complex 0.7426416354938628 1.8593128608560312 0.0629828050926166 1.0 0.151791892696756 6 Q9BUN8,Q9UBV2 2 +Rna polymerase ii transcription repressor complex 0.549866824504298 1.8402708642328496 0.0657284806668476 1.0 0.1571618002296541 2 P35222 1 +Postsynaptic endosome 0.6499851939591262 1.8315699327866852 0.0670155198237276 1.0 0.1594024505467778 4 Q4V328,P20339,Q86Y82 3 +Pore complex 0.6501963203933951 1.819712509317674 0.0688027973104168 1.0 0.1623817314761392 10 P45880,P21796 2 +Lipid droplet 0.4684222446249555 1.8161193922025003 0.0693520595895198 1.0 0.1625742657600281 31 Q9H6V9,O43760,Q07065,Q8NBX0,Q01105,P51572 6 +Postsynaptic density intracellular component 0.6464759052373941 1.81347451912507 0.0697586651912052 1.0 0.1629490871517639 4 Q9UQB8,P35222 2 +Endoplasmic reticulum tubular network 0.6148855883444533 1.811298773911992 0.0700946153900692 1.0 0.1633150757553786 12 Q9H6H4,Q00765,Q9NQC3,Q8NHH9,P50402 5 +Endosome lumen 0.7291834589543013 1.797117674838437 0.0723169403167856 1.0 0.1670620036149726 6 P07858,Q99538,Q9UIQ6,P05067 4 +Proton transporting atp synthase complex coupling factor f o 0.7093007785939816 1.7963660202494487 0.0724363242896972 1.0 0.1670620036149726 7 P00846,O75964,P24539,P56134 4 +Platelet alpha granule lumen 0.5995722734938729 1.788893109913007 0.0736320316524317 1.0 0.1689969563481428 13 Q8NBX0,P05067,P10909,Q9NUQ9,Q9Y6I9 5 +Collagen trimer 0.5398046759396321 1.7797211439575025 0.0751216083639876 1.0 0.171949209094454 2 Q5KU26 1 +Calcium channel complex 0.6642470386142744 1.7785104011757442 0.0753200652014525 1.0 0.1719713769386547 9 Q9NWR8,P62942,Q8NE86,Q9BPX6,P54652,Q8IYU8,P0DP25 7 +Late endosome 0.3696285562260878 1.7460531037002691 0.0808017246833547 1.0 0.181754002929719 70 Q9GZP9,Q14108,Q96PU5,O15118,O43633,Q99538,Q8IV08,P07602,P11279,Q9BUN8,P51809,Q14849,Q8IY95,O95772,Q9BXS4,Q8TCT8,O15400,Q9NZJ7,Q13501,Q9HC07,P51790 21 +Hippocampal mossy fiber to ca3 synapse 0.6328101865561071 1.7427203252402028 0.0813824795174396 1.0 0.1826094552718903 4 O60716,P47756,Q15375 3 +Glial cell projection 0.6738429610159714 1.7383677743979806 0.0821460311949664 1.0 0.183869863436399 5 Q8IXJ6,P05067 2 +Mitochondrial proton transporting atp synthase complex coupling factor f o 0.6726564694630683 1.732535928162469 0.0831781858990807 1.0 0.1857238415540749 5 O75964 1 +Ubiquitin conjugating enzyme complex 0.6304412200177592 1.7304094344150054 0.0835571494297022 1.0 0.1861138462847402 4 Q5VTR2,P61088,Q9UNE7 3 +Nuclear inner membrane 0.4970433717909717 1.7259543115429647 0.0843556326213097 1.0 0.1873672742891179 21 P62995,Q9BTV4,Q14739,Q03252,Q9H1E5,O75844,P50402,O94901,Q99720 9 +Growth cone membrane 0.5303344184670092 1.722428746770447 0.0849918799542703 1.0 0.1874631484827799 2 Q96A65 1 +Clathrin coated vesicle 0.411649668672738 1.719953227020524 0.0854409440342676 1.0 0.1875583132896814 51 P49755,Q14108,Q9BVK6,P20339,P42892,Q5VW38,P09496,P51572,O43752 9 +Sec61 translocon complex 0.6223907977271725 1.6884759395632694 0.0913199038270551 1.0 0.1968850569328055 4 Q15041 1 +Translocon complex 0.6223907977271725 1.6884759395632694 0.0913199038270551 1.0 0.1968850569328055 4 Q15041 1 +Recycling endosome 0.4345412265821637 1.6879142529921047 0.0914276902088317 1.0 0.1968850569328055 41 Q15907,P51790,O15400,P04439,O14773,P10321,Q96C92,Q86Y82,P01889,P05067,Q9H223,O14828,Q9Y2I1,O15127,O15126 15 +Azurophil granule lumen 0.4277910280004668 1.6868366942058608 0.0916347575625791 1.0 0.1968850569328055 44 P10619,O00584,O75629,P04066,P16278,P15586,O43681,P61916,Q9BTY2,P08236,P17900,P06280 12 +External side of plasma membrane 0.4785731905199742 1.6783746235470782 0.093273988369344 1.0 0.1994662051748179 25 P00813,P07858,P42892,O96005,P08183 5 +Endoplasmic reticulum exit site 0.5053790350192366 1.6663525684570808 0.0956432120868089 1.0 0.2040537850376649 19 Q9Y3A6,O75340,P04439,O15027,Q5JRA6,Q96PC5,Q9NR31 7 +Equatorial microtubule organizing center 0.5193844332642867 1.6558332801269482 0.0977555861484735 1.0 0.2073811468146345 2 Q9BSJ2 1 +Manchette 0.5184965966262279 1.650417782257757 0.0988575165725849 1.0 0.2089540547508697 2 P62826 1 +Smooth endoplasmic reticulum 0.5951167567908384 1.6360307904119724 0.1018331434648061 1.0 0.213755745844328 11 O00264 1 +Nucleotide activated protein kinase complex 0.6085816594500012 1.61620780762581 0.1060493912916586 1.0 0.2190725520786872 4 P54619 1 +Nadh dehydrogenase complex 0.4637049781397179 1.5860923373078906 0.1127183648576983 1.0 0.22972355790909 26 O95298,Q9Y6M9,P56556,Q9NX14,O75489,O43674,Q96CU9,P03886,O95168,P51970,O75438,O43676,O75306,Q86Y39 14 +Neuromuscular junction 0.4932885867586417 1.5790882897953846 0.1143158072900341 1.0 0.2324591527705827 19 P07196,O43760,Q15375,P05067,P57105,Q7L0J3 6 +Insulin responsive compartment 0.5986962307996379 1.5642262432202994 0.1177644462502105 1.0 0.2368287208254786 4 Q5VZ89,P61026 2 +Cytolytic granule 0.5947587049485373 1.5434670507712254 0.1227174960159185 1.0 0.2440952813766414 4 P11279 1 +Phagophore assembly site 0.6374708767340612 1.5375350449090943 0.1241623399822335 1.0 0.2464311366531913 8 Q13501,Q86Y82,Q9H0U4,P51149,Q7Z3C6 5 +Anchored component of synaptic membrane 0.4989641905889386 1.5307175384953282 0.1258392172686386 1.0 0.2481375041812334 2 Q9NQX3 1 +Rough endoplasmic reticulum membrane 0.5112975932887894 1.529292310370157 0.1261919950676502 1.0 0.2482390798544614 17 Q15041,Q5BJF2,Q96A33,Q9Y5M8 4 +Haus complex 0.5918872063923624 1.5283095038902117 0.126435711363853 1.0 0.2482390798544614 4 O94927 1 +Intrinsic component of presynaptic membrane 0.5860479048130424 1.497439439750344 0.1342789524244783 1.0 0.2591697577514825 4 P27824,Q92542 2 +Proteasome core complex beta subunit complex 0.6434962453815168 1.476133390356379 0.1399080867124535 1.0 0.2667227294162858 7 P20618,P28072,P28074,P49721 4 +Cytoplasmic side of endoplasmic reticulum membrane 0.6066850682662972 1.4759812775526289 0.1399489183984463 1.0 0.2667227294162858 9 Q8TCT9 1 +Postsynaptic density membrane 0.6064138853417116 1.474539910202861 0.1403362802719403 1.0 0.2669026123752351 9 Q99720,Q15375,P57105,Q9BQT9 4 +Intraciliary transport particle b 0.5331557134399153 1.462470253500032 0.1436123900391896 1.0 0.2719976867478208 3 A0AVF1,Q9Y366 2 +External encapsulating structure 0.4089143298046915 1.4583525812554892 0.1447433838311596 1.0 0.2735710013904281 42 Q53GQ0,Q32P28,P53634,Q9NZJ7,P07858,Q96JX3,Q92896,P07602,P10909,P84157,P20073,P49257 12 +Blood microparticle 0.4762831662738552 1.455329953788243 0.1455779379473432 1.0 0.2745786779917798 19 P38435,P04062,P27105 3 +Plasma membrane raft 0.4630883541584932 1.45139452177566 0.1466700343246574 1.0 0.2760669447722374 20 P09601 1 +Cytoplasmic side of membrane 0.391502975852167 1.443657551401703 0.1488353274659732 1.0 0.2789896776162585 49 Q8TCT8,Q9NR28,P17900,P20339,Q8TCT9,Q9Y5X3,Q05639,O43464 8 +Mcrd mediated mrna stability complex 0.6133651028772525 1.4376704155939386 0.1505275910515635 1.0 0.2810054005081442 5 O60506,P11940,Q14103 3 +Photoreceptor inner segment 0.6116637159624059 1.4291226683094596 0.1529689792406054 1.0 0.2849790185852588 5 P35613,Q15555,P05023 3 +Juxtaparanode region of axon 0.5724375225806027 1.4252620282448347 0.1540814720609002 1.0 0.2858980400333387 4 Q14168 1 +Striated muscle thin filament 0.6088760538807637 1.4151090447111534 0.1570365267046167 1.0 0.2883058226739298 5 P09493,P67936 2 +Myofilament 0.6088760538807637 1.4151090447111534 0.1570365267046167 1.0 0.2883058226739298 5 P09493,P67936 2 +Postsynaptic specialization membrane 0.5372602235731383 1.4130261540662885 0.1576480341809343 1.0 0.2883882713631148 13 P57105,Q15375,Q99720,Q9BQT9 4 +Presynaptic active zone membrane 0.5640810657264345 1.3808080890922372 0.1673379756735817 1.0 0.3000883776351043 4 Q13277,P27824 2 +Caveola 0.5174424561758615 1.3522166590990456 0.1763060159470779 1.0 0.311268954511217 14 P09601 1 +Pinosome 0.4637466706126155 1.3126797580735174 0.1892908812211011 1.0 0.3312555663919837 2 Q06481 1 +Intraciliary transport particle 0.5488575438515715 1.2996039276570983 0.193736752841277 1.0 0.3343966750404235 4 Q7Z4L5 1 +Anchored component of membrane 0.535053515193402 1.2886734343783708 0.197511641831042 1.0 0.3375855641802613 11 P61020,P20339 2 +Golgi transport complex 0.5005920663114293 1.2757325809900069 0.2020500671295626 1.0 0.3424494510765449 3 Q96JB2,P60953 2 +Pole plasm 0.5788056412990688 1.2633916365131157 0.206448468319512 1.0 0.3476424300167753 5 Q9Y2W6 1 +Sperm midpiece 0.5781037063904693 1.2598406936864353 0.2077268365406306 1.0 0.3483678491540194 5 Q15388 1 +Retromer complex 0.5482417223300345 1.2583681955291892 0.2082586285021579 1.0 0.3483678491540194 10 O60749,Q5VZ89,Q9Y5X3 3 +Sarcoplasmic reticulum membrane 0.5471298360356538 1.252145283994274 0.2105169294205406 1.0 0.3507146511200223 10 P16615,P62942,Q9BVC6,O75298,Q8WXH0 5 +Recycling endosome membrane 0.4228906096765696 1.2508966649489337 0.2109721808075215 1.0 0.3507220013059345 26 Q15907,P10321,P01889,Q9H223,O14828,O15127,O15126 7 +Messenger ribonucleoprotein complex 0.6121108790601194 1.2431722952597577 0.2138043495432824 1.0 0.3535209608899557 6 P67809,Q99729 2 +Apical part of cell 0.3356958928583424 1.2163089738620625 0.223867244318014 1.0 0.3633002567279589 67 Q13277,P05023,P07858,P05026,Q15154,Q8NCM8,P08195,P36551,Q99538,P05067,Q9Y289,P54709,P41208,Q86UE4,Q13895,O14641,P53985,P35222,Q16625,O43865,P61421,Q99808,P20020,Q9Y6M7,P30825,P98164,Q9NV96,P55011,P78536,P08183,Q14254,P51790 32 +Ciliary transition zone 0.5722075272033158 1.2022564652953385 0.229264178397162 1.0 0.3690100115191072 8 P41208,Q15555,A6NIH7,Q15019 4 +Cytoplasmic ubiquitin ligase complex 0.5714546609352142 1.198364487740618 0.2307751512288656 1.0 0.3707868831913519 8 Q9BUN8,Q9UBV2 2 +Specific granule 0.3842416323317869 1.1972077196574442 0.231225601712556 1.0 0.3708565548593988 41 Q13277,P51790,Q07065,O00264,Q8WVQ1,Q9BS26,Q9Y251,P30519,P50995,Q4KMQ2,O60784,Q6IAA8,Q92820,Q08722,P27105,Q9UHA4,O15126 17 +N terminal protein acetyltransferase complex 0.4840142095914779 1.180264861186107 0.2378948891282024 1.0 0.3782339647376296 3 Q9BXJ9,Q9GZZ1 2 +Nata complex 0.4840142095914779 1.180264861186107 0.2378948891282024 1.0 0.3782339647376296 3 Q9BXJ9,Q9GZZ1 2 +Mitotic cohesin complex 0.4412548091151314 1.1725649747822993 0.2409703019468452 1.0 0.3820621483560057 2 Q9UQE7 1 +Crd mediated mrna stability complex 0.5963843391960879 1.16763148914436 0.2429554427588505 1.0 0.3829280421337591 6 P67809 1 +Photoreceptor connecting cilium 0.5543686461756104 1.1396572213467409 0.2544291359560702 1.0 0.3948636164497103 5 P41208,Q15555 2 +Proton transporting atp synthase complex catalytic core f 1 0.5186473290501525 1.1379773483055462 0.2551299410280294 1.0 0.3952778508104334 4 P36542 1 +Intrinsic component of nuclear inner membrane 0.569916042984438 1.1109918234502891 0.2665718688179619 1.0 0.4079869507981066 7 Q14739,Q9UH99,O94901,Q9BTV4 4 +Chloride channel complex 0.5836289300425694 1.1063397480503143 0.2685794937234713 1.0 0.4091570548195358 6 Q9C0H2,Q96S66 2 +Late endosome membrane 0.3762861202084884 1.0911611654079278 0.2752019725918047 1.0 0.4185459048933791 39 Q8TCT8,O15118,O43633,Q14108,Q8IV08,Q9HC07,P11279,P51809,Q14849,O95772,Q9BXS4,P51790 12 +Oxidoreductase complex 0.3370712993763636 1.060036931621135 0.2891277980121187 1.0 0.4339298583015488 59 P13674,O43169,P03886,Q9UDW1,P22695,O43676,Q86Y39,O14949 8 +Aryl hydrocarbon receptor complex 0.4214264575318222 1.0490677194377034 0.2941469518523383 1.0 0.4392915953073446 2 O00170 1 +Sarcolemma 0.3956734127453549 1.0449329174422806 0.2960539747329858 1.0 0.4402932105457979 27 Q92542,P05023,O75298,P35613,Q9H9S5,P11279,Q96QD8 7 +Dendrite cytoplasm 0.4873656426250279 1.0095360290674726 0.3127176316186801 1.0 0.457280517503399 11 P33176,P27824,P23246,Q9UQB8,Q8N2K0 5 +Clathrin coated endocytic vesicle 0.4021889315749051 0.996709517624032 0.318905528550643 1.0 0.4640941477789709 21 P20339,Q14108 2 +Apical plasma membrane 0.3473543320961231 0.9916914853634254 0.3213480458646121 1.0 0.4661593467876777 50 Q13277,P05023,P07858,P05026,P36551,Q9Y289,P54709,Q86UE4,P53985,Q16625,O43865,P61421,Q99808,Q9Y6M7,P30825,Q9NV96,P55011,P78536,P08183,Q14254,P51790 21 +Paraspeckles 0.5584582900372492 0.9855939159164104 0.3243324247842356 1.0 0.4697406025094414 6 Q15233,P23246,Q8WXF1 3 +Vesicle lumen 0.293351308221262 0.9703852701449128 0.3318544880635825 1.0 0.4775978493300531 129 P10619,P00813,O00231,P15586,Q9BTY2,O00571,O75874,P16278,P17900,Q92520,Q8WVQ1,O75629,P05067,P61916,Q9NUQ9,Q9Y6I9,P14174,Q6UXV4,Q8NBX0,P10909,P08236,O00584,P04066,O43681,P06280 25 +Sperm annulus 0.4444511020667514 0.9528633698729936 0.3406593015628898 1.0 0.488725391691012 3 Q15019 1 +Mcm complex 0.5511173795097929 0.950494527332202 0.3418610333485175 1.0 0.4889095783053366 6 Q14566,P33991 2 +Microbody lumen 0.3918769933371871 0.9417334612860616 0.3463291190364246 1.0 0.4937493387201609 23 Q15067,Q9BQG2,O14734,O15254,O00116,Q13011,O75874 7 +Brisc complex 0.4809002072845589 0.9365104162699032 0.3490104520754271 1.0 0.4967945653761157 4 P34897,Q9NWV8,Q9NXR7 3 +Cul4a ring e3 ubiquitin ligase complex 0.3998224326723963 0.91526185238312 0.3600541805327035 1.0 0.5084383518823714 2 Q16531 1 +Presynaptic membrane 0.4313839164374805 0.9143382065336004 0.3605391606103314 1.0 0.5084383518823714 16 Q96CX2,Q13277,Q92542,P27824,P35222,P20020,Q06787,P09496,Q9BTU6 9 +Ribbon synapse 0.4314500853504271 0.8787742248974564 0.3795237042836303 1.0 0.5292205234378908 3 P16615 1 +Integral component of presynaptic active zone membrane 0.4313203078744935 0.8780374320031263 0.3799234054098579 1.0 0.5292205234378908 3 P27824,P20020 2 +Intrinsic component of presynaptic active zone membrane 0.4313203078744935 0.8780374320031263 0.3799234054098579 1.0 0.5292205234378908 3 P27824,P20020 2 +Collagen containing extracellular matrix 0.3536683685145079 0.8705706069183997 0.3839886512868169 1.0 0.5327443771346525 35 Q32P28,P53634,Q9NZJ7,P07858,P10909,P07602,P84157,P20073,P49257 9 +Acrosomal vesicle 0.415521203934213 0.8671496466484111 0.3858600214314731 1.0 0.5342226132584682 17 P45880,Q9Y487 2 +Dendritic shaft 0.5210307451120522 0.8076987784689714 0.4192640069819762 1.0 0.5666378375258595 6 Q9UQB8,P05067 2 +Annulate lamellae 0.4789266504377941 0.7610574817203294 0.4466227347199534 1.0 0.5974644806606131 5 O14980,Q8TD16 2 +Clathrin coated endocytic vesicle membrane 0.4126886706298233 0.7371506438367724 0.461030744262209 1.0 0.6078133256481512 15 Q14108 1 +Apical dendrite 0.4425513902571975 0.735267582577279 0.4621765469543604 1.0 0.6084434021321131 4 P10909 1 +Presynaptic active zone 0.4097574987922092 0.7183672041950945 0.4725309027678652 1.0 0.6192865011669045 15 Q13277,Q99623,P27824,P35222,P05067,Q7L0J3 6 +Photoreceptor ribbon synapse 0.367268422610247 0.7173921405864341 0.4731321677411257 1.0 0.6192865011669045 2 P11142 1 +Camp dependent protein kinase complex 0.402309058614561 0.7152973149658131 0.4744253473357427 1.0 0.6196836266882374 3 P13861,P10644 2 +T tubule 0.4891108696863558 0.7130774517195365 0.4757978314646633 1.0 0.620102753167823 7 P05023,O75298 2 +Potassium channel complex 0.4016120533158491 0.7114471317301196 0.4768072012031423 1.0 0.6205305147086609 3 P0DP25 1 +Postsynaptic specialization intracellular component 0.4659626183541683 0.697656063091767 0.4853923116744667 1.0 0.6275555762143324 5 Q9UQB8,P35222 2 +Sarcoplasm 0.3645247880664304 0.697244993738607 0.4856494854348017 1.0 0.6275555762143324 20 P16615,P62942,Q9BVC6,O43852,O75298,Q8WXH0,P52789 7 +Sorting endosome 0.3925399644760217 0.6616603215159944 0.5081889392441956 1.0 0.6529761969696223 3 P01130,P18031 2 +Mitotic spindle microtubule 0.4815521156831572 0.6248792474658619 0.5320503136250068 1.0 0.6766698258123106 6 O94927 1 +Transcription preinitiation complex 0.4193070772875244 0.6168476766595179 0.5373352014950137 1.0 0.6792893933790071 4 P13984,P19447,P29083 3 +Neuron projection terminus 0.3936958032413833 0.6164229269020528 0.5376154254953502 1.0 0.6792893933790071 15 P51790,P20339,Q13641,Q14141,Q9UQB8,P11142,P61421 7 +Autophagosome 0.3368576732242844 0.6142157725859945 0.5390727520295291 1.0 0.680045930404658 30 O95721,O43633,Q9UMX0,Q8TBX8,Q13501,P11279,Q9P253,Q969Q5,Q9Y6I9,P13473 10 +Photoreceptor outer segment 0.4723666639427494 0.5834814051791316 0.5595692712081339 1.0 0.6983117891378219 6 P35613,Q15555 2 +Nuclear envelope 0.2689622545265406 0.5455576209929549 0.5853700620818527 1.0 0.7200942400714012 189 Q8TD16,Q15125,O15173,Q86Y07,Q9H1E5,P80303,Q6ZRP7,Q99720,O15118,P62995,Q9H2V7,Q96KC8,O43633,Q14739,Q9P035,P05067,P50402,P41208,Q86UE4,Q9BTX1,Q5BJF2,Q99735,P50995,P42167,Q07812,Q9NQC3,O75844,Q8NFH4,O94901,Q9C0E2,P67809,Q6NUM9,O14681,Q8N1F7,Q8N201,Q96S66,P56134,Q12981,Q96AG4 39 +Ciliary basal body 0.3349032613349283 0.5207661896433113 0.6025296588062381 1.0 0.7328498253304178 26 P31749,Q96C92,P41208,O43805,Q9P2S5 5 +9plus0 non motile cilium 0.396656618689939 0.4935365492800207 0.6216335213700632 1.0 0.7490848385821793 11 P35613,P41208,Q15555,Q9BV73 4 +Ciliary membrane 0.4203347616684163 0.4830183719048804 0.6290826915163625 1.0 0.753326117692735 5 O95721,Q15019 2 +Mhc class i peptide loading complex 0.4192895051932305 0.4783062298662877 0.6324322629322252 1.0 0.756096839279865 5 P04439 1 +Myelin sheath 0.381121392358455 0.4659078413939895 0.6412814681195913 1.0 0.763327524012751 13 Q8N3R9,Q9NR77,P0DP25 3 +Rna cap binding complex 0.4143957345971515 0.4563951011699708 0.6481058878436108 1.0 0.7671913214053186 5 Q7L576,Q53F19,P06730,Q06787 4 +Perinuclear region of cytoplasm 0.2643620725939149 0.4550160910730182 0.6490976625679645 1.0 0.7671913214053186 198 Q9UMX0,Q99584,P07858,P42892,P46934,Q01105,Q92905,Q9H2J4,Q9NQX7,P27105,P16278,P51572,O15118,Q9UL15,P09601,Q99538,P05067,P11279,Q8IY95,Q86UE4,O43752,Q9Y487,Q10472,P55327,Q93050,P10909,O95831,Q9Y5X3,Q9UIQ6,O75503,Q9BZG1,Q07065,O15400,O60499,Q9H223,Q8NEW0,O95684,Q9H6S0 38 +Basolateral plasma membrane 0.3040900185899833 0.454827601165839 0.6492332716250284 1.0 0.7671913214053186 46 P53985,Q99808,P05023,Q9Y6M7,P35613,P05026,P00533,Q6P4Q7,P30825,P57105,Q9Y289,P22413,Q9BY67,P54709,P55011,Q14254,Q14168 17 +Beta catenin destruction complex 0.4428817707736638 0.4547467443196331 0.6492914476437988 1.0 0.7671913214053186 6 P25054,P49841,P35222 3 +Myosin ii complex 0.3843005355511621 0.4471368803623948 0.6547762319075714 1.0 0.7719589745323038 4 P60660 1 +Dna replication preinitiation complex 0.3997349638813963 0.4467976453269367 0.6550211715844905 1.0 0.7719589745323038 10 Q14566,P33991,Q9BRT9 3 +Cortical granule 0.3478389579632887 0.42848271508643 0.6682997152125043 1.0 0.7825463246254464 3 P27797,P07686 2 +Myosin filament 0.347838957963287 0.4284827150864212 0.6682997152125107 1.0 0.7825463246254464 3 Q7Z406,P35580 2 +Trans golgi network transport vesicle 0.3737185516595369 0.4244394200331117 0.671245377083415 1.0 0.7839801775935784 13 Q9BVK6,P09496 2 +Oligosaccharyltransferase complex 0.4146852183757586 0.4153134230949507 0.6779124760733948 1.0 0.7882236885324758 8 P46977,P04843,Q9H0U3 3 +Cuticular plate 0.3442865600947247 0.4110937675891252 0.6810037797926731 1.0 0.7895816766585328 3 Q9Y5X1,Q01082 2 +Cop9 signalosome 0.3870240769546055 0.3839567414577615 0.7010105098878272 1.0 0.8063391092270336 10 Q92905,Q99627 2 +Presynaptic cytosol 0.3674859342611654 0.3707790859835375 0.7108020797691672 1.0 0.8124726407399139 4 P42858,Q9UQB8,P11142 3 +Microvillus membrane 0.3339253996447574 0.361600156438879 0.7176508477461834 1.0 0.8151869355321361 3 P15311,P35222 2 +Ficolin 1 rich granule membrane 0.33249106213614 0.3590522228071325 0.7195560222752464 1.0 0.8161116304678907 18 Q93050,P10253,P11279,P42785,P13473 5 +Nuclear outer membrane 0.3701370229277381 0.3554330020234236 0.722265228751203 1.0 0.8168821632525267 11 P50402,Q99720 2 +Autophagosome membrane 0.343973061251263 0.35115007280185 0.7254757640927418 1.0 0.8168821632525267 16 O95721,O43633,P11279,Q9Y6I9,Q7Z3C6,P13473 6 +Mmxd complex 0.3306690349319109 0.3464470056629797 0.7290068043076885 1.0 0.8168821632525267 3 P18074,P05141 2 +Rpap3 r2tp prefoldin like complex 0.4001553706614994 0.31410355884838 0.7534423866581244 1.0 0.8351543858502545 7 Q9UHV9,P19388,O15212 3 +Endolysosome 0.3608526984880504 0.3095506291619293 0.7569027054189594 1.0 0.8378351939692249 11 P07858,P09496 2 +Scf ubiquitin ligase complex 0.3879562251639559 0.2992623828979153 0.7647398541776085 1.0 0.844558571853461 8 Q96K76 1 +Schaffer collateral ca1 synapse 0.3348609211948315 0.2979283799035498 0.7657578269494607 1.0 0.844558571853461 16 P07196,Q13277,P47756,Q00535,P35222,Q15375,Q16352,O60716,Q9UQB8 9 +9plus2 motile cilium 0.3029448195148565 0.2565352435808453 0.7975375702526244 1.0 0.8680486577062614 22 P05023,Q15019,Q13501,P05026,P41208,Q15388 6 +Copii vesicle coat 0.3572772518101397 0.2463420297238436 0.8054174771485723 1.0 0.8734944305742254 10 Q9NR31,O75340 2 +Meiotic spindle 0.3057860231108525 0.2379165648042471 0.8119458075064161 1.0 0.878482934249816 3 Q8IXJ6 1 +Ciliary tip 0.3456925245354728 0.1970970618223623 0.8437515826573843 1.0 0.9081558015390296 10 Q7Z4L5,Q15555,Q2M1P5,Q8NCM8 4 +Ap 3 adaptor complex 0.2952535055180753 0.1963252318490788 0.8443556135055523 1.0 0.9081558015390296 3 Q9P253 1 +Clathrin coated vesicle membrane 0.2912903255147301 0.1830494791499013 0.8547591956899081 1.0 0.916100737968831 25 P20339,Q14108 2 +Protein phosphatase type 2a complex 0.343601895734591 0.1761548893553545 0.86017225960047 1.0 0.9197381789859485 5 P30154,P63151,P30153,Q15257 4 +Extrinsic component of cytoplasmic side of plasma membrane 0.295631800018492 0.1705927686727348 0.8645439843380656 1.0 0.921169087405822 19 P31749,P46940,P63218,Q9Y5X3,Q9H0H5,Q9Y5X1 6 +Tertiary granule 0.274014654051899 0.1443724012356785 0.8852064090933691 1.0 0.938792827338835 44 O15400,Q8WVQ1,Q93050,P10253,P11279,Q08722,O75874,P27105,P42785,Q13510,P13473 11 +Intermediate filament cytoskeleton 0.27359661082245 0.1405851339487581 0.8881976929800834 1.0 0.9408698817498324 34 P07196,O75298,Q3SXM5,P08670,Q9NZQ3 5 +Cilium 0.2480800929494326 0.1374487411199676 0.8906761067580129 1.0 0.9423994579054004 92 P05023,P05026,Q96C92,A6NIH7,Q9BV73,P31749,Q7Z4L5,O95721,P35613,P05067,Q9NUQ9,P41208,O43805,Q92973,Q9BZG1,Q15555,P09622,Q13501,Q10713,Q15388,Q9P2S5 21 +Main axon 0.3210718441735674 0.1323388983621041 0.894716241487095 1.0 0.9444802966335384 11 Q14168,P05067 2 +Clathrin coated pit 0.2819582265974902 0.1253470267172046 0.9002488237978294 1.0 0.9481233277223382 27 Q96D71,P05067 2 +Endoplasmic reticulum plasma membrane contact site 0.2705743043220785 0.1105650449884605 0.9119612675446844 1.0 0.9571390722732804 3 Q9NTJ5,A0FGR8 2 +Non motile cilium 0.2983624112374005 0.1047156077785058 0.916601476837674 1.0 0.960902123589322 16 Q15555,Q15019,P35613,P41208,Q9BV73 5 +U2af complex 0.2634695085849551 0.0891393184193804 0.9289711901706352 1.0 0.972750292236148 3 Q15637,P26368 2 +Cul3 ring ubiquitin ligase complex 0.3235555555555595 0.0477877753744671 0.9618853792641102 1.0 1.0 6 Q9UBV8,O75340,Q92990,Q14145,Q9NXV2 5 +Cell pole 0.2691738229197436 0.0343197618290509 0.9726221664904932 1.0 1.0 4 P08195,Q9BTU6,P35241 3 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5e25df6af7179450c66ba3ee8a30f5cabcd68c6d --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc complex", "Blood microparticle", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine head", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Deuterosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle a", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of external side of plasma membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Procentriole replication complex", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spherical high density lipoprotein particle", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC8", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG9A", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD8", "BRI3BP", "BRIX1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf43", "C12orf73", "C14orf2", "C19orf70", "C1D", "C1QBP", "C1orf35", "C2CD2L", "C2CD5", "C3orf58", "C8orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARS2", "CASK", "CAST", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC58", "CCDC8", "CCDC86", "CCDC93", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP135", "CEP170", "CEP250", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGN", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLU", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREB1", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM162A", "FAM208A", "FAM210B", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1L", "FNBP4", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GGA1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNG12", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN3", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK2", "HOXD13", "HP1BP3", "HPS3", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGF2BP1", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ISCU", "ISOC1", "IST1", "ISY1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPRIP", "IVD", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8C", "LRWD1", "LSG1", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LZTS2", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METTL13", "METTL15", "MFAP1", "MFF", "MFN1", "MFSD10", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MMS22L", "MOB4", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPHOSPH8", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCK1", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C3A", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PAOX", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PAWR", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PDZD11", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF5A", "PHF6", "PHF8", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN23", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RICTOR", "RIDA", "RIF1", "RILPL1", "RINT1", "RIOX1", "RIOX2", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SASS6", "SATB2", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC38A2", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLK", "SLMAP", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS2", "TBC1D10A", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM177", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT112", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC5", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGCG", "UGGT1", "UGT8", "UHRF1", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "USE1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS52", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS2", "WASF2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR61", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WNK3", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC11", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF207", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCD3", "ABHD10", "ABHD12", "ACAT2", "ACBD3", "ACBD5", "ACOT8", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL6", "ADA", "ADAM17", "ADPGK", "AFG3L2", "AGK", "AGPS", "AHCYL1", "AHSA1", "AIFM1", "AIP", "AKAP9", "AKT1", "AKT2", "ALDH3A2", "ALG1", "ANKLE2", "ANO6", "ANXA11", "ANXA7", "AP3S1", "APC", "APLP2", "APOL2", "APOOL", "APP", "ARFIP2", "ARL1", "ARL6IP1", "ARL6IP5", "ARMC1", "ARMC10", "ASAH1", "ASNA1", "ATAD1", "ATAD3A", "ATAD3B", "ATG9A", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATPAF2", "B4GAT1", "BABAM1", "BABAM2", "BAG5", "BAIAP2", "BAX", "BCAP31", "BCL2L13", "BICD2", "BNIP1", "BRI3BP", "BSG", "BYSL", "C12orf73", "C14orf2", "C19orf70", "C3orf58", "CADM1", "CALM3", "CALR", "CALU", "CAMLG", "CANT1", "CANX", "CAPZB", "CCDC47", "CCDC93", "CCT4", "CD47", "CDC42", "CDK1", "CDK2", "CDK5", "CDS2", "CEP250", "CERS1", "CERS2", "CETN2", "CHCHD3", "CHMP2A", "CHST14", "CISD1", "CKAP4", "CLCC1", "CLCN3", "CLCN7", "CLN5", "CLPP", "CLPTM1", "CLSTN3", "CLTA", "CLU", "CNNM4", "COA3", "COA7", "COG3", "COLEC12", "COPS4", "COPS5", "COPS8", "COQ8A", "COQ9", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE3", "CPOX", "CPT1A", "CPT2", "CREG1", "CRTAP", "CTNNB1", "CTNND1", "CTSA", "CTSB", "CTSC", "CYB5B", "CYFIP1", "CYP51A1", "DCTPP1", "DDB1", "DDRGK1", "DDX3X", "DENND4C", "DERL1", "DERL2", "DHCR24", "DHFR", "DHRS7", "DIABLO", "DLD", "DNAJC1", "DNAJC11", "DOLPP1", "DPM1", "DVL2", "DYM", "DYNC2H1", "EBP", "ECE1", "ECH1", "EEF1A2", "EGFR", "EHD4", "EI24", "EIF4E", "EMC3", "EMC4", "EMC7", "EMD", "ENPP1", "EPDR1", "EPHA7", "EPHX1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERGIC1", "ERGIC3", "ERP44", "ESYT2", "EXOC4", "EXOG", "EZR", "FADS2", "FAM162A", "FAM3C", "FAM49B", "FECH", "FGFR1OP", "FKBP14", "FKBP1A", "FKBP7", "FKBP9", "FKRP", "FLOT2", "FMR1", "FOXRED1", "FUCA1", "FUCA2", "FUNDC2", "GAA", "GADD45GIP1", "GALNT1", "GAPVD1", "GBA", "GGCX", "GGH", "GHITM", "GINS4", "GLA", "GLB1", "GLB1L2", "GLG1", "GLMN", "GLT8D1", "GM2A", "GNG5", "GNS", "GOLGA5", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOSR1", "GPAA1", "GPAM", "GPAT4", "GPHN", "GPR107", "GPR108", "GPR89B", "GRIPAP1", "GSK3B", "GTF2E1", "GTF2F2", "GUSB", "HACD3", "HAUS5", "HCCS", "HEXA", "HEXB", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMOX1", "HMOX2", "HNRNPAB", "HNRNPD", "HNRNPR", "HPS6", "HPSE", "HS2ST1", "HSD17B11", "HSD17B12", "HSDL1", "HSPA13", "HSPA2", "HSPA8", "HTRA2", "HTT", "ICMT", "IDH1", "IDH2", "IFT52", "IKBIP", "ILVBL", "IMPAD1", "INA", "INTS1", "IQGAP1", "ITM2B", "ITM2C", "JAGN1", "KCTD12", "KCTD5", "KDELR1", "KDELR3", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIF5B", "KIF7", "KIFBP", "KLC2", "L2HGDH", "LACTB", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR3", "LBR", "LDAH", "LDLR", "LETM1", "LGMN", "LMAN1", "LMAN2", "LMF2", "LMNB1", "LMNB2", "LNPEP", "LPCAT1", "LPGAT1", "LRP2", "LRRC59", "MAGT1", "MAN1A1", "MAN1A2", "MAPK3", "MAPRE2", "MBOAT7", "MCCC2", "MCL1", "MCM4", "MCM6", "MCU", "MCUB", "MESD", "MFF", "MFN1", "MGST2", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MMAB", "MPP2", "MPP5", "MPV17L2", "MRPL15", "MRPL23", "MRPL40", "MRPL45", "MRPL55", "MRPS9", "MSMO1", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTX1", "MTX3", "MXRA7", "MYH10", "MYH14", "MYL6", "NAA15", "NAA50", "NAGLU", "NAP1L1", "NCBP3", "NCKIPSD", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFA6", "NDUFA8", "NDUFAF2", "NDUFB1", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS2", "NDUFS3", "NEDD4", "NEDD4L", "NEFL", "NENF", "NISCH", "NNT", "NONO", "NPC1", "NPC2", "NSUN2", "NT5C3A", "NUCB1", "NUCB2", "NUDT12", "NUP37", "NUP93", "NUPL2", "OCIAD1", "OCLN", "OPA1", "OPA3", "OS9", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PCDH19", "PCM1", "PCYOX1", "PDCD6", "PDCL3", "PDP1", "PEF1", "PEX14", "PEX16", "PEX19", "PFDN2", "PFDN6", "PGRMC1", "PGRMC2", "PHB2", "PI4K2A", "PIGL", "PIP4K2C", "PISD", "PITRM1", "PLBD2", "PLD3", "PLD6", "PLXNB2", "PMPCA", "PNPLA6", "POFUT2", "POLDIP2", "POLR2E", "PON2", "POR", "PPHLN1", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPT1", "PPT2", "PRCP", "PREPL", "PRKAG1", "PRKAR1A", "PRKAR2A", "PSAP", "PSMB1", "PSMB2", "PSMB5", "PSMB6", "PSMD11", "PSMD3", "PSMG1", "PSPC1", "PTDSS1", "PTDSS2", "PTPA", "PTPN1", "PTPRF", "PXMP2", "QSOX2", "RAB10", "RAB11B", "RAB1B", "RAB24", "RAB2A", "RAB34", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RACGAP1", "RAN", "RCN1", "RCN2", "RDH13", "RDX", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "RFT1", "RHEB", "RMDN3", "RNASET2", "RNF20", "RPN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "S100A13", "SACM1L", "SAMM50", "SAR1A", "SAR1B", "SC5D", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCO1", "SDCCAG3", "SDHB", "SEC11A", "SEC16A", "SEC62", "SEC63", "SEL1L", "SEPT2", "SEPT6", "SERAC1", "SET", "SF1", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SHMT2", "SIGMAR1", "SIRT2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A10", "SLC25A11", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC29A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC38A2", "SLC3A2", "SLC4A7", "SLC5A6", "SLC7A1", "SMC3", "SNAP29", "SNX2", "SNX27", "SNX5", 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1.0306256348057904e-05 0.0002142043583912 +Lipid binding 38 155 3.513915603627477 0.000441553078583 30.883495145631063 138.65533980582524 0.9844637598707308 0.4289871747751645 8.92748670410201 14.760635317682617 1.446857667744565 0.4068298387995807 0.0211648739998195 0.019847779732521 0.0001032702299204 0.0060508412169139 0.0038312964905451 +Peptide binding 23 77 3.500021753931068 0.000465220190958 17.133495145631066 70.30339805825243 1.21997288878307 0.3503559587509399 5.621054768990946 6.443005397350486 1.219878183292811 0.3773673755377006 4.573166976431905e-05 0.0333931709842731 0.014090869270841 0.000849080574553 1.5150672302140797e-07 +Sterol binding 7 18 3.404192181758956 0.0006636004679658 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 1.0548054151524908e-05 0.0006661905409434 2.315121590530167e-05 0.0001968893298034 0.0002681869997004 +Organic anion transmembrane transporter activity 19 30 3.392748966874204 0.0006919501929933 12.951456310679612 30.182038834951456 1.56101282472555 0.2452312368187786 6.880574373146614 3.5222410835885483 1.575669523214114 0.314839840161206 0.0045503184686084 0.0627750690965546 0.1997425917545389 0.0043610876134259 0.0080072027585734 +Active ion transmembrane transporter activity 22 42 3.231727458421484 0.0012304435184176 16.271844660194176 41.71116504854369 1.2957221273899948 0.3267733012969381 7.788084220174416 5.097264791179653 1.6571109350293016 0.3632481416270505 0.071826970048759 0.1100218853789511 0.3182249609881349 0.0239861063430982 0.1205470075659955 +Alcohol binding 7 17 3.2157516238489725 0.0013010338179026 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 0.0001286107099808 0.0017444833819259 0.0001168596637319 0.001212131153867 0.0026180560643756 +Passive transmembrane transporter activity 17 36 3.2130872019713053 0.0013131641331107 10.728155339805824 34.00242718446602 0.8598494327527568 0.3171523987434088 5.464704354730218 4.259483301090722 1.5882390061019254 0.3339692919660049 0.0620268204556762 0.0002061120351411 0.0049705397344002 0.0202782391208114 0.009325311019984 +Cholesterol binding 7 15 3.1513945929228933 0.0016249280158644 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 2.3972009836983418e-06 0.0003865639533612 9.164358234292652e-06 6.775190892351933e-05 6.711779371444596e-05 +Molecular transducer activity 14 35 3.1465961916396816 0.0016518291725802 10.91747572815534 33.40533980582524 1.343848990749489 0.2329582295822712 4.7124072380860955 5.830391636254363 1.6098335072319665 0.2956883791113679 0.3995465719080269 0.3530243184113045 0.2415839094743012 0.5944333056930783 0.3757175797359404 +Hydrolase activity hydrolyzing o glycosyl compounds 14 26 3.1246451518572225 0.0017801966731452 8.830097087378642 20.84223300970874 0.5983257656540719 0.2104301479001341 3.2223833352824554 2.4557961681485057 1.9540573665272416 0.2728112677124137 1.5382913426521858e-06 1.0 0.0111977735740575 1.7655246071967724e-06 4.054361134438966e-09 +Tetrapyrrole binding 9 16 2.976338349077311 0.0029171282529596 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 0.0012554527627416 0.0001247827123008 0.0018235094886023 0.0002941476334404 0.0010655904765625 +Organic acid transmembrane transporter activity 17 24 2.942959421237813 0.0032509102698035 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.0179815096442294 0.0421554091664212 0.1411421437582085 0.0238750792658836 0.0168669379700177 +Phospholipid binding 19 95 2.910647124128402 0.0036068111324893 18.890776699029125 88.4635922330097 0.777309720287493 0.452120200534915 6.970479526806733 10.51702894240924 1.1988133109990275 0.3785217149858343 0.4532663067956414 0.0564535296707662 0.0273932643594073 0.1944983364276845 0.0994901520048429 +Hydrolase activity acting on glycosyl bonds 15 34 2.906178410222425 0.0036587277213768 10.133495145631068 28.40776699029126 0.6089784953463463 0.2409908190925149 3.36301188653944 3.2424277527979313 1.935823411407979 0.3010513017078077 1.2838410065323028e-05 1.0 0.0054554424478239 9.1039452255183e-06 3.110051619014076e-07 +Snap receptor activity 10 16 2.899460041977272 0.0037380598712715 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 0.0197718902859207 1.0 0.0428134756181982 0.0086864012748381 0.0001753252601336 +Protein transporter activity 7 15 2.8540395685397137 0.0043167154414318 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 7.324796794058032e-06 0.0002227197090729 0.0017488676437986 2.2359581100408143e-05 1.4416472873703857e-06 +Secondary active transmembrane transporter activity 13 22 2.8314442463313028 0.0046338311382345 9.080097087378642 21.490291262135923 1.2627683473613005 0.2947710034053126 5.466215032972134 3.0675886156990426 1.4241587428281404 0.3340388164945335 0.2867902029257726 0.3467229085425889 0.5778229381468787 0.1629443488297355 0.2565571949899699 +Amyloid beta binding 6 14 2.8096478845877577 0.0049595727981137 3.5898058252427183 10.560679611650484 1.053866189591651 0.2544642672774957 2.009490338022764 1.9342863324228672 1.0942484681219342 0.2534200432416059 0.005207787405201 0.1635258499471353 0.0498890213657128 0.001820540651884 0.0017822844690718 +Ceramide binding 4 5 2.7665857654249573 0.0056646682365923 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 0.0065763731833925 0.0017062060788896 0.0002366501305723 0.0033170374819039 0.0002481332774246 +Calcium ion binding 28 95 2.75009093295915 0.0059578728677796 21.00485436893204 81.67961165048544 0.6464856503310022 0.4940276647939897 7.408010340962093 8.52860815905726 1.2261945166831902 0.3858741960292539 0.1476416465194207 0.7414992917830734 0.7551722514244638 0.1333136257671366 0.0085626528130174 +Palmitoyl protein hydrolase activity 3 5 2.7114987002437374 0.0066979803656612 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0003591188143491 0.0561990347849709 0.0057815105752346 0.0001405335592956 0.0020033682110678 +Serine hydrolase activity 11 18 2.703576800874813 0.0068597593551349 6.934466019417476 18.83009708737864 1.2767207242593377 0.1489147276149277 2.386872767465543 1.965791668457755 1.709796217367629 0.2208345231085202 0.0006110060951695 0.2068720246529641 0.0111977735740575 0.0001382861626823 0.002003382390012 +Glycolipid binding 5 10 2.69949451353603 0.0069444900812332 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 0.0015284527669486 0.0786913117950012 0.0005470061355849 0.0006143549700213 0.0001004910149917 +Endopeptidase activity 24 68 2.6365949710740155 0.0083742754781381 19.08495145631068 62.800970873786405 1.5604938505680932 0.2935756148549138 5.629332570724372 6.156865220927466 1.27979578418692 0.359984229645684 5.158606763752966e-05 1.0 0.0779089110374132 0.0001865238893652 0.000442217922264 +Primary active transmembrane transporter activity 21 57 2.6361982920690745 0.0083840721477141 17.696601941747574 52.529126213592235 1.0080198242353189 0.3544097082146772 7.649017203625277 6.455721193615876 1.66885648871365 0.3767837436492733 0.077053160418382 0.0197758267942588 0.1111181143510491 0.0701527069806367 0.0137155839156238 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 14 35 2.6355541863649545 0.0084000012827623 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.0668842579486905 0.0099984448704361 0.0616304522136525 0.0247674911995091 0.0005335000665693 +Hexosaminidase activity 3 5 2.6136383142742994 0.0089583815173226 2.5194174757281553 4.973300970873787 0.3568105957806153 0.2227497456156347 1.091499214132507 0.3065083294438748 1.6445593916296413 0.2548912926080147 9.838042555940574e-05 1.0 0.0841007109914387 3.788095303003865e-05 0.0005732271800539 +Macromolecule transmembrane transporter activity 8 12 2.5961466569894087 0.0094275815978588 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 0.0002841526274441 0.0001122733832082 0.0008978593047678 0.0011814468070448 2.7537597807274675e-05 +Serine type carboxypeptidase activity 3 5 2.579015819886138 0.0099082248975441 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 4.307219092179311e-06 0.0238038053541035 0.047623940504538 1.6228361660218084e-06 2.661109756617399e-05 +Metal ion transmembrane transporter activity 12 24 2.5783908496390104 0.0099261653367623 9.563106796116504 24.67233009708738 0.8657396859235934 0.3700615753207195 4.93288923178502 4.839352380624028 1.4450904591933955 0.3424002804304004 0.3227538341798355 1.0 1.0 0.172108822769145 0.5484863305876572 +Protein transmembrane transporter activity 6 11 2.577918623467859 0.0099397402818948 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 0.0001223776796777 6.765318543664244e-05 0.0005470061355849 0.0006143549700213 7.850220860580527e-06 +Inorganic anion transmembrane transporter activity 10 19 2.572922643255412 0.0100843744674754 7.427184466019417 19.274271844660195 1.0921593405593897 0.2441056926448881 3.717191605498929 3.7816647851785734 1.4014196343960104 0.2816216967014333 0.0050265218632011 0.0001075756277076 0.0015842643936449 0.0014919193154812 0.0001692953162957 +Cargo receptor activity 3 11 2.534011250401363 0.0112765111250074 3.7063106796116503 7.95873786407767 0.9623237890522576 0.1578680760704802 1.9530058934839476 1.7914972745396005 1.6202205206532496 0.203966946010782 0.0537276740302863 0.0078974776787256 0.0024390672757694 0.0291459656321865 0.0448872219881859 +Monooxygenase activity 7 9 2.522527619694639 0.0116514799881253 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 0.0012397233896807 0.0073558029266518 0.0279813079733609 0.0004102788019959 2.8968816708506228e-05 +Phosphatidylcholine binding 2 7 2.509383683469673 0.0120942039221558 2.2524271844660193 7.929611650485437 1.2697801287388335 0.1567893034984199 1.081337239384838 1.04388968498945 1.4953842980517238 0.2256102823610289 0.0120270758321215 5.590323461425328e-05 0.000453663444764 0.0061570039439817 0.00630824692371 +Anion channel activity 7 12 2.460012695700751 0.0138932101019293 4.20873786407767 11.21116504854369 1.03959259790327 0.2192420598609839 2.3076742714116403 2.0905640066649145 1.3937691950814175 0.2662450395835827 0.0100782524716357 0.0003140311505353 0.0024390672757694 0.0042924995678 0.0002995500484788 +Chemoattractant activity 0 5 2.452421816338128 0.0141898212005049 1.366504854368932 3.686893203883495 0.5714079756163727 0.4338826918091285 1.053954374150973 0.5841956201266594 1.068730194478316 0.3170892913465473 0.2214576049043232 1.0 0.075113296023457 0.1775366954381628 0.3290745839784397 +Fad binding 5 9 2.425322984888382 0.0152947725995697 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 0.0445840383189574 1.0 0.0260710687649276 0.0239571113561098 0.0075122167669424 +Protein lipid complex binding 1 5 2.3805433418130724 0.0172871272813637 1.3810679611650485 4.075242718446602 0.904959910455646 0.2381476109936121 0.9668941495076666 1.0318560378441015 1.279214127988033 0.237092245379572 0.050899384243609 1.0 0.0057815105752346 0.032628233248221 0.1129571724371578 +Nucleobase containing compound transmembrane transporter activity 9 12 2.379470678247674 0.0173375223000591 6.529126213592233 14.04126213592233 1.4296604886183193 0.212054291115069 3.2696940585469636 1.915888183904924 1.3255809572534116 0.2748813593420038 0.0160815615877132 0.1430638950507344 0.2685353106225043 0.0069928111010265 0.0181161163925661 +Sphingolipid binding 4 7 2.369938408646308 0.0177910487077153 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 0.01674854618918 0.0032958763634803 0.0006517968090871 0.0086586519898169 0.0013491401517078 +Scavenger receptor activity 2 6 2.3184590860644647 0.0204243840674838 2.128640776699029 4.245145631067961 0.8895147156183107 0.1752904943890176 1.2029313295363038 0.9324780265795692 1.5451274177295422 0.2106852326062687 0.050899384243609 0.0561990347849709 0.0057815105752346 0.032628233248221 0.0181181417645757 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 2 5 2.3136853718224737 0.0206849868792788 1.5048543689320388 4.490291262135922 0.278788560706552 0.5101874933406457 1.0180295683783271 0.9176811810851436 0.921984521977564 0.2894246869117938 0.0179201169927304 1.0 0.0660385900079411 0.0112385866308786 0.003457584268524 +Gated channel activity 6 13 2.303844368080524 0.0212313815201226 4.317961165048544 13.019417475728156 0.8697524591818097 0.2583579989367679 2.2914716766946497 2.0107989163575497 1.3733766112751231 0.2762671399351702 0.112911215803706 0.0029449884503582 0.0203848430395501 0.0564393829037643 0.0704094801772502 +Serine type exopeptidase activity 4 7 2.289961613439369 0.0220235419894945 3.783980582524272 6.997572815533981 1.020609253431403 0.1137432544246352 1.3363606860118669 0.0492066381861973 1.87035730934538 0.1990592265121372 3.0548129410123283e-06 0.0424464003246627 0.0032139762811053 9.14133433735114e-07 2.858966188275996e-05 +Hexosyltransferase activity 18 36 2.2871348455160248 0.022187953553411 9.633495145631068 33.87864077669903 0.7349501031127185 0.3949358882560483 4.261380470236419 4.330948695045228 1.2646745007039175 0.3422146027467064 0.4680024333685998 0.4243503559946278 0.3038848977676358 0.5218778121271003 0.4817045887202535 +Amino acid transmembrane transporter activity 9 11 2.275870382984098 0.0228537686047527 4.325242718446602 10.521844660194176 0.9562493229862624 0.2921494362491497 2.574340086864074 1.34633933573134 1.106576767449958 0.2884960270895668 0.1244418575004597 1.0 1.0 0.0713646261968556 0.3081896593873433 +Signaling receptor regulator activity 5 19 2.273322022936746 0.0230067813386556 4.072815533980583 17.339805825242717 0.7311308082630681 0.4520633016494398 2.421493327854957 2.496807274147909 0.9157780911218903 0.317372323464707 0.1872372451113385 1.0 0.5107150602013826 0.0994768290011166 0.2817090990841858 +Quaternary ammonium group binding 4 12 2.268541940363499 0.0232961957680302 2.8567961165048543 12.12864077669903 0.9707568143407772 0.2573327609820879 1.4849985868988949 1.260087490061347 1.304146106648176 0.2795917987269193 0.0288824454338437 0.0001506452861526 0.0011959433226113 0.0152248647419399 0.0035298468720628 +Oligosaccharyl transferase activity 2 5 2.260260605564594 0.0238050814109558 2.0800970873786406 4.449029126213592 0.3253650630697351 0.4526354423109099 1.2831590228622023 0.6896066341264963 1.063820674508784 0.3223663395492768 1.0 1.0 1.0 1.0 0.2586577321272367 +Voltage gated anion channel activity 5 7 2.231350776401122 0.0256579027007106 2.854368932038835 6.25 1.127126362633441 0.1649553590552043 1.5417035527207152 0.9966570336472054 1.4583344406160936 0.2334940994157564 0.0029552410756802 0.0009934566258862 0.0039921150854813 0.0014684283121974 5.489393781591606e-05 +Quinone binding 1 5 2.227190154694913 0.0259345678415312 2.0825242718446604 5.371359223300971 0.6144040024425256 0.3400691378536611 1.308295206174148 0.7946759106689059 1.1785397932704846 0.300626350021166 0.3342830117953164 0.0607401038440192 0.1191939669275513 0.2721697661507766 0.129364196063302 +Sterol transporter activity 3 9 2.2010363837507456 0.0277334482197761 2.621359223300971 8.364077669902912 0.5454888897585024 0.2973249899153176 1.425267849835305 1.6080715320593837 1.318674977748992 0.2709274408896192 0.0049168061240519 1.0 0.2012104780589677 0.1053546389470493 0.0234644839392777 +Sulfur compound transmembrane transporter activity 2 6 2.1934409103733006 0.0282756275169029 2.9635922330097086 6.752427184466019 1.4746434057995097 0.1672652154050841 1.7026919602194592 1.5538455059459366 1.0954441166028872 0.2266277553273111 0.0586100994566341 0.0084566179175882 0.031964215627013 0.0319451393300601 0.1652047572335966 +Protein carrier chaperone 8 11 2.171237870972773 0.0299131960037115 3.3980582524271843 10.118932038834952 0.8288787693114796 0.3398938251553178 1.8569721980092944 2.0920401213092656 1.1849901066971258 0.3127406939001886 0.01674854618918 1.0 1.0 0.3559534457378639 0.0013491401517078 +Glucosyltransferase activity 1 10 2.15670744223264 0.0310284667532072 2.342233009708738 9.048543689320388 0.4761205412145978 0.5159240070556952 1.9500716601415085 1.525693480881991 0.8525181118658677 0.3136461905246437 0.1046893250830714 0.083126337411673 0.012905013470629 0.0688460117016781 0.2173267675800807 +Proton channel activity 6 11 2.130323803129245 0.0331448897021495 3.655339805825242 10.75485436893204 0.46898650441807 0.3141755537304957 2.268964442606705 0.8649601417133376 1.3429609354721883 0.2856466957651606 0.0142767807743484 0.0029386578360865 0.0115435449528709 0.0073447144383531 0.0079370796506279 +Proton transporting atp synthase activity rotational mechanism 6 11 2.130323803129245 0.0331448897021495 3.655339805825242 10.75485436893204 0.46898650441807 0.3141755537304957 2.268964442606705 0.8649601417133376 1.3429609354721883 0.2856466957651606 0.0120270758321215 0.0026008925831016 0.0102498345034834 0.0061570039439817 0.00630824692371 +Oxidoreduction driven active transmembrane transporter activity 17 32 2.1277574801797177 0.033357196414256 9.733009708737864 29.83252427184466 0.7626445826297276 0.3795490924215395 4.629116134249794 3.4519743101246267 1.4198222355288384 0.35536187545778 0.0416596233750574 0.0032330061916283 0.0222198796395938 0.0166327696461577 0.0099258782765325 +Peptidyl proline dioxygenase activity 4 5 2.120067078689861 0.0340003888030522 1.8786407766990292 4.366504854368932 0.8778603077568147 0.3426860899699969 0.9827789493022476 0.8268224457358132 0.991058988324824 0.287268871727031 0.2454527277981396 0.0424464003246627 0.0841007109914387 0.1973959389561772 0.00771353919978 +Procollagen proline dioxygenase activity 4 5 2.120067078689861 0.0340003888030522 1.7766990291262137 3.951456310679612 0.957382133221728 0.3172306101859959 0.9288476923748724 0.5000706896961519 1.010775728794482 0.283372586770602 0.1967019277312726 0.0331691185540615 0.0660385900079411 0.1571881112173651 0.003457584268524 +Iron ion binding 11 27 2.116922199147603 0.0342664512872608 6.524271844660194 22.196601941747577 0.9076096695164306 0.382669917893863 2.4429198675966717 3.289094676807881 0.9378690899634522 0.3126784916965753 0.0392483782405235 0.0345877004093447 0.1182995834221419 0.0155889061230085 0.0006517545393382 +Phosphatidylserine binding 1 10 2.1128214699539924 0.0346160513178337 2.029126213592233 10.060679611650484 0.6615116985008255 0.3340719518205703 1.5854698894895154 0.9597266622759548 1.1646704221215245 0.2873190862432436 0.2128446667457567 0.1263420182810564 0.0299460957191466 0.1457934990596532 0.3982984602367481 +Organophosphate ester transmembrane transporter activity 7 10 2.0910479900398893 0.0365237622750933 5.665048543689321 12.143203883495143 1.4298365636921646 0.2056324024803549 3.029697948284232 1.927415248708952 1.2819429632405106 0.2680490563295835 0.0288824454338437 0.1006582454154426 0.1933613304033528 0.0152248647419399 0.0201372619620155 +Nucleotide transmembrane transporter activity 7 10 2.0910479900398893 0.0365237622750933 5.606796116504855 12.029126213592232 1.4217258291760082 0.2036087501116975 3.0234925518113496 1.8899648667798992 1.291115513359647 0.2666064512499804 0.0255113558567383 0.0963063052639835 0.1854358412925483 0.0133829456596615 0.0171177319456962 +Phosphotransferase activity for other substituted phosphate groups 2 5 2.087335907699329 0.0368577811007115 1.9053398058252424 5.174757281553398 0.0857884151299792 0.4696075786898813 1.1939453367119757 1.5543686288302525 1.070932812476897 0.3031413201326607 0.4818793905666583 1.0 1.0 1.0 0.2722934148112151 +L amino acid transmembrane transporter activity 8 9 2.0701126742133256 0.0384417942782517 3.628640776699029 8.201456310679612 0.919975936290114 0.2876791162304417 2.2759730869054327 1.0290432051153906 1.15482978403653 0.2925518180165951 0.0586100994566341 1.0 1.0 0.0319451393300601 0.1652047572335966 +Palmitoyltransferase activity 3 5 2.0634222413426224 0.0390725286070672 1.8786407766990292 5.084951456310679 0.875863834441912 0.3421870647647222 1.2306088543936362 0.6827036113457149 1.018188317250868 0.2997914787323893 0.4483625919687176 1.0 1.0 1.0 0.2355870590704462 +Voltage gated channel activity 5 11 2.059823924827103 0.0394153765085831 3.2257281553398056 10.116504854368932 0.8578192560085278 0.2690365421745596 1.8168622808181427 1.411127559025233 1.234834479111217 0.2694186191218866 0.0859419119875361 0.0115082778780227 0.0428134756181982 0.0479498850625808 0.0231294135439989 +Clathrin heavy chain binding 1 5 2.0460136751497493 0.0407550252398554 0.9563106796116504 4.172330097087379 0.3682910274765735 0.3434838107739949 1.107360186700709 1.195424695125345 1.3132806864166615 0.2873136636013117 0.0234121875355895 1.0 0.075113296023457 0.1775366954381628 0.0544194668097373 +Sodium ion transmembrane transporter activity 7 9 2.035827556318049 0.0417676743176063 3.033980582524272 6.733009708737864 0.6330876716410718 0.3951789521880264 1.773267150762252 1.4834287460359985 1.0827590126064015 0.3202441368223486 0.3502876200553227 1.0 1.0 0.2511786735203468 0.5862027736389052 +Tap binding 3 5 2.0220780358405097 0.0431682907124664 1.8592233009708736 3.895631067961165 0.8127354819395453 0.3477955376218754 1.070154411615344 1.0456940556701602 1.051123567423606 0.2887299843781864 1.0 1.0 1.0 1.0 0.042147958906207 +Exogenous protein binding 6 17 2.0150401106169245 0.0439004465029904 4.509708737864078 15.157766990291265 0.7214109752050332 0.2527966464979699 2.499010078306418 1.9009100692398744 1.5211756979359785 0.2791170769282048 0.0489414442151608 0.1952735388158895 0.0705821305211966 0.0940672040532474 0.1740747384317906 +P type transmembrane transporter activity 3 5 2.012073840064091 0.0442121538188384 2.842233009708738 5.473300970873787 0.6050493013674468 0.3730987003611934 1.6045635356324264 1.3712604140019378 1.17652933932801 0.3174788438558891 1.0 1.0 1.0 1.0 0.4505109675601652 +Oxidoreductase activity acting on a heme group of donors 5 6 2.007826470082956 0.0446617349644664 3.111650485436894 6.483009708737864 0.8850005512180296 0.2757097651603665 1.538237610319269 1.0226572421183926 1.2777814224392188 0.2966482201944345 0.0762554308819813 0.0697581245313758 0.1362380906066266 0.0495157384890535 0.0336357980244025 +Neutral amino acid transmembrane transporter activity 4 5 2.0016124653769163 0.0453264272995665 2.2014563106796117 4.604368932038835 0.4961979429298074 0.422433136266165 1.3637817977156623 0.906438855008838 1.0374761107148884 0.3077443591708454 0.5133658415211507 1.0 1.0 0.4301270919610729 0.682815470497098 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6d2d94f3c9fee1872a1cfe2d4caff4ce532a2f07 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 1388, + "title": "Average number of proteins per term", + "value": 17.544668587896254 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..74f1543f609b8642ab29b64702326c49ae121b0c --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a1c889091535b94c6c64f47fc1f7a0f549793c95 --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,388 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter activity 0.612121372921582 6.021144216694722 1.7318835771068207e-09 2.4038515192381717e-06 2.403854406412267e-06 183 O60830,Q9NS69,P05023,Q99595,O15173,Q9UDW1,P20674,P21796,P00846,O43676,P06576,O75964,Q8NE01,P00403,P16615,Q70HW3,Q9H2D1,P45880,Q9UBX3,Q9C0H2,Q6P4Q7,P51798,Q14849,Q9Y487,O95298,P04062,Q93050,Q07812,Q6P4A7,Q9H0U3,P28288,Q8WTV0,P61421,P51991,Q99808,Q9Y619,O95202,P03886,Q9HD20,P10606,Q9HC07,P30536,Q13423,P56385,O14925,Q8TB61,P05026,O96008,Q9BSK2,O43772,P17900,Q96AA3,P12236,Q9H2V7,Q6NUK1,Q9Y289,Q9Y277,L0R6Q1,O95168,Q9Y5J9,P13073,Q02978,Q96NB2,P38435,P24539,Q9H9B4,Q96QD8,Q15758,P12235,Q9Y6M7,P30825,Q15388,Q8NEW0,O15118,Q9BQT8,P61916,P53985,Q7L0J3,P36542,P49755,O43808,Q96S66,P08183,P51790,O75438,O75306,Q8IXU6,Q9NWR8,P98194,P0CG08,O75489,Q07820,Q9H936,O43681,P56134 95 +Ion transmembrane transporter activity 0.642934715183949 5.576561209059465 2.4531962106905873e-08 3.404978411637597e-05 1.7025181702886675e-05 102 P56385,P05023,Q8TB61,P05026,Q9UDW1,P21796,P20674,P00846,P06576,O43772,O75964,P00403,P16615,Q70HW3,Q9H2D1,P45880,P12236,Q9BQT8,Q9UBX3,Q9C0H2,Q6P4Q7,Q6NUK1,Q9Y289,P51798,Q9Y277,Q9Y487,P13073,Q02978,Q96NB2,P53985,Q9NWR8,P24539,P98194,Q93050,Q6P4A7,Q9H0U3,P0CG08,Q9H9B4,Q96QD8,Q15758,P61421,P12235,P36542,Q99808,Q9Y619,O95202,Q9Y6M7,P30825,Q9HD20,O43808,P10606,Q9H936,Q9HC07,O43681,Q96S66,Q13423,P56134,Q8NEW0,P51790 59 +Cation transmembrane transporter activity 0.6550022925655002 4.885957843947356 1.029272213539932e-06 0.0014276105607659 0.0004762099441316 70 P56385,P05023,P05026,Q9UDW1,P20674,P00846,P06576,O43772,O75964,P00403,P16615,Q70HW3,Q6P4Q7,Q9Y289,Q9Y487,P13073,Q96NB2,P24539,P98194,Q93050,Q9H0U3,Q9H9B4,Q96QD8,Q15758,P61421,P12235,P36542,Q99808,Q9Y619,O95202,Q8NE86,P30825,Q9Y6M7,O43808,Q9HD20,P10606,Q9H936,Q9HC07,P56134,Q13423,Q8NEW0,P51790 42 +Inorganic molecular entity transmembrane transporter activity 0.6205029872878867 4.652024969271731 3.2869126742607335e-06 0.0045518510707958 0.0005160182431385 77 P56385,P05023,P05026,Q9UDW1,P21796,P20674,P00846,P06576,O75964,P00403,P16615,P45880,Q9UBX3,Q9C0H2,Q6P4Q7,Q9Y289,P51798,Q9Y277,Q9Y487,P13073,Q02978,Q9NWR8,P24539,P98194,Q93050,Q9H0U3,P0CG08,Q96QD8,P61421,P12235,P36542,O95202,Q9Y6M7,Q8NE86,Q9HD20,Q9H936,P10606,Q9HC07,O43681,Q96S66,Q13423,P56134,P51790 43 +Er retention sequence binding 0.9952648712636876 4.165294637411708 3.109507189025251e-05 0.0422424676758104 0.0008143388638428 2 P24390 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.9884581237052384 4.134340525064857 3.559753356729978e-05 0.0482094282396124 0.000856869116149 2 P30519 1 +Phospholipase d activity 0.9863865048831016 4.124896528462986 3.709014653785481e-05 0.0501793276366115 0.0008580187232423 2 P09601 1 +Lysophosphatidic acid binding 0.9742527374963011 4.069362377521793 4.714197603106207e-05 0.063339702438076 0.0009943523082055 2 P50897 1 +Vitamin d binding 0.9411068363421136 3.915707858989192 9.013934533497192e-05 0.1176081528454881 0.001343015313457 2 P04062 1 +Sulfotransferase activity 0.9381473808819184 3.901846674795281 9.54616200947722e-05 0.1241032440193478 0.0013738393175995 2 Q8NCH0 1 +Sphingosine n acyltransferase activity 0.9378514353358982 3.900459254313245 9.601038458728615e-05 0.1247702113521809 0.0013738393175995 2 P27544 1 +Steroid binding 0.8096649009159145 3.896020119667645 9.778626927037236e-05 0.1269251415563496 0.0013849728749722 23 O15118,P45880,Q14108,O00264,P04062,P38435,O15173,P21796,P30536,O95772,Q14849 11 +L ornithine transmembrane transporter activity 0.93074874223143 3.867089802702555 0.0001101418769158 0.1417718835587187 0.0014842419918365 2 Q9Y619 1 +Solute proton antiporter activity 0.8872447469665594 3.6596412553302713 0.0002525685884968 0.2957412721352999 0.0026161582151765 2 O95202 1 +Active transmembrane transporter activity 0.5235991100353224 3.628751945967435 0.0002847947239785 0.3265566345344735 0.002874810994182 78 P05023,P05026,Q9UDW1,P20674,O75438,O43676,P06576,O75306,P00403,P16615,P12236,Q9UBX3,Q9Y289,P51798,O95168,O95298,P13073,Q02978,P53985,P98194,P28288,Q96QD8,Q15758,P61421,P12235,O75489,O95202,P03886,Q9Y6M7,Q8NE86,Q9HD20,Q9H936,P10606,Q15388,P08183,O14548,P51790 37 +Beta galactosidase activity 0.878958271678012 3.6195142888690848 0.000295156513306 0.3361756594181498 0.002874810994182 2 Q8IW92 1 +Galactoside binding 0.8789582716780121 3.6195142888690848 0.000295156513306 0.3361756594181498 0.002874810994182 2 P06280 1 +Mannosyl oligosaccharide 1 2 alpha mannosidase activity 0.8718555785735445 3.5849593825121535 0.0003371306689843 0.3737566618360015 0.0031541561059983 2 P33908 1 +Anion transmembrane transporter activity 0.6347256635903251 3.5800268694334236 0.0003435588784561 0.3793212593538966 0.0031580114125639 45 Q8TB61,P21796,Q9H2D1,P12236,P45880,Q9BQT8,Q6NUK1,Q9C0H2,Q9UBX3,Q9Y289,P51798,Q9Y277,P53985,Q02978,Q96NB2,P0CG08,Q9H9B4,Q96QD8,Q15758,Q99808,Q9Y619,Q9Y6M7,P30825,Q9H936,O43808,O43681,Q96S66,P51790 28 +Proton transmembrane transporter activity 0.661758244399058 3.5491972370542744 0.0003864075328188 0.4151718899705888 0.0034826860750164 36 P36542,P13073,O95202,Q9UDW1,P24539,P20674,P61421,Q9H936,Q93050,P10606,P00846,P56134,Q13423,P06576,O75964,Q9Y487,P51790,P00403 18 +Lipid binding 0.439645473051901 3.513915603627477 0.000441553078583 0.458282711460135 0.003854563981593 155 Q13277,P50897,Q14108,Q99584,P05023,O15173,P21796,Q9BWH2,A6NIH7,Q96L92,Q9H4A5,O15118,P31749,P45880,O43633,O00264,Q9H4A6,P07602,O15254,P61916,Q9BQE5,O95772,Q14849,O60749,O75208,O60313,Q9UM22,Q15067,P04062,P38435,Q9Y5X3,O14773,Q8WTV0,Q9NQZ5,Q9NZJ7,P20073,P30536,O43292 38 +Sulfatide binding 0.9317282728246882 3.508099531799389 0.0004513201621381 0.4655802971733733 0.0038980309474162 3 P50897 1 +Peptide binding 0.511630584253538 3.500021753931068 0.000465220190958 0.4757967949565938 0.0039134886366654 77 P24390,P01889,P42892,O43731,Q9NQX7,P55786,P40855,O00264,Q6P179,O15212,P09496,Q9UHV9,Q9NZ08,Q9Y287,Q92973,Q99735,P10909,Q9UIQ6,O14773,Q8WTV0,Q15392,P48637,Q15388 23 +Sulfuric ester hydrolase activity 0.8532110091743137 3.493537452470074 0.0004766661173727 0.4840628406836047 0.0039617519216368 2 P15586 1 +Sodium channel inhibitor activity 0.8467002071618837 3.4613646938811375 0.0005374442078853 0.5258222804097901 0.0043119801187566 2 P46934 1 +Sterol binding 0.7932033360496614 3.404192181758956 0.0006636004679658 0.6020318088084351 0.0050059109039244 18 O15118,P45880,Q14108,P21796,P30536,O95772,Q14849 7 +Acyl coa oxidase activity 0.906943132302812 3.394525264850388 0.0006874769650555 0.6150131801208194 0.0051176783969077 3 O15254 1 +Organic anion transmembrane transporter activity 0.6774974592506514 3.392748966874204 0.0006919501929933 0.6173977361641321 0.0051176783969077 30 Q8TB61,Q9H2D1,P12236,Q9BQT8,Q6NUK1,Q9UBX3,Q9Y289,P53985,Q02978,Q96NB2,Q9H9B4,Q96QD8,Q15758,Q99808,Q9Y619,Q9Y6M7,P30825,Q9H936,O43808 19 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.9064535227945496 3.3922654201913303 0.0006931725782555 0.6180467849709755 0.0051176783969077 3 Q16850,Q15800 2 +Magnesium ion transmembrane transporter activity 0.82391240011838 3.3477285254459384 0.0008147678155301 0.6774053469219888 0.0057698863671215 2 Q6P4Q7 1 +Aspartic endopeptidase activity intramembrane cleaving 0.8952042628774418 3.3401669080064247 0.0008372805276357 0.6873378814433775 0.0058399264942635 3 Q8TCT8,Q8TCT9 2 +Ganglioside binding 0.8943161634103016 3.3360393975977556 0.0008498111973391 0.692733373568448 0.0058976897095339 3 Q9UM22,P07602 2 +Interleukin 6 receptor binding 0.8138502515537158 3.2970318074088905 0.0009771243474812 0.7425453363869239 0.0064770513020568 2 Q9NZ08 1 +P type potassium transmembrane transporter activity 0.8079313406333256 3.267058928959882 0.0010867105727778 0.7789075726357347 0.0067943886261967 2 P05023 1 +Galactosidase activity 0.879218472468918 3.265544141084466 0.0010925397589927 0.7806911300373731 0.0068002026254792 3 Q8IW92,P06280 2 +Active ion transmembrane transporter activity 0.6053914312760037 3.2317274584214837 0.0012304435184176 0.8189364448966631 0.0074905947524721 42 P05023,P05026,Q9UDW1,P20674,P06576,P00403,P16615,P12236,Q9Y289,P51798,P13073,Q02978,P98194,Q96QD8,P61421,P12235,O95202,Q9Y6M7,Q9HD20,Q9H936,P10606,P51790 22 +Alcohol binding 0.7813928464522039 3.2157516238489725 0.0013010338179026 0.8358559175464797 0.0077784106521642 17 O15118,P45880,Q14108,P21796,P30536,O95772,Q14849 7 +Passive transmembrane transporter activity 0.6180527818574255 3.2130872019713053 0.0013131641331107 0.838600012257404 0.0077784106521642 36 P56385,P36542,P45880,Q9NWR8,Q9C0H2,P24539,P21796,P51798,P00846,Q9Y277,Q07812,P0CG08,Q96S66,P06576,P56134,O75964,P51790 17 +Manganese ion transmembrane transporter activity 0.8644168146832337 3.1958230050708987 0.0013943261678128 0.8558174701042078 0.0079642992630628 3 Q9HC07,Q9HD20 2 +Transition metal ion transmembrane transporter activity 0.8644168146832337 3.1958230050708987 0.0013943261678128 0.8558174701042078 0.0079642992630628 3 Q9HC07,Q9HD20 2 +17 beta hydroxysteroid dehydrogenase nadpplus activity 0.7928381177863298 3.1901140009987636 0.0014221668147538 0.8612903704214596 0.0080900308970422 2 Q53GQ0 1 +Cholesterol binding 0.8094228878645859 3.1513945929228933 0.0016249280158644 0.895360535086612 0.0089500003413486 15 O15118,P45880,Q14108,P21796,P30536,O95772,Q14849 7 +Molecular transducer activity 0.6127758917835783 3.1465961916396816 0.0016518291725802 0.8992017803695856 0.0090086361634545 35 O15118,Q15629,Q14108,O15173,Q99442,Q9BUN8,Q08722,P30536,Q9UBG0,O15031,Q9Y6I9,Q8WTV0,P10586,Q99720 14 +L glutamine transmembrane transporter activity 0.7842556969517636 3.146027429945386 0.0016550448283003 0.8996514153620238 0.0090086361634545 2 Q96QD8 1 +High density lipoprotein particle binding 0.8512925138600116 3.1334905680309793 0.0017274047014597 0.9092558216993344 0.0092931694791708 3 Q9BQE5 1 +Hydrolase activity hydrolyzing o glycosyl compounds 0.6692656090659084 3.1246451518572225 0.0017801966731452 0.9156782088009036 0.0095035114704829 26 Q9NUJ1,P04062,P33908,P04066,P16278,O60502,P10253,O60476,Q9BTY2,P06865,Q8IW92,P17900,P54802,P06280 14 +Volume sensitive anion channel activity 0.8483449644668557 3.119424495498168 0.0018120469563231 0.9193311431452758 0.009636479599144 3 Q9C0H2 1 +Carnitine o acyltransferase activity 0.7753773305711777 3.100162633875612 0.0019341441033688 0.9319281532586152 0.0100924511860001 2 P50416 1 +O palmitoyltransferase activity 0.7753773305711777 3.100162633875612 0.0019341441033688 0.9319281532586152 0.0100924511860001 2 P50416 1 +Tetrapyrrole binding 0.7587565443560756 2.976338349077311 0.0029171282529596 0.9826626338501973 0.0134071987255231 16 O00264,Q6UW02,P09601,O43169,O15173,P30519,P53701,Q16850,Q8WUJ1 9 +Amino acid cation symporter activity 0.8167497199722975 2.9670762822048165 0.0030064635756608 0.9846901212296568 0.0136371615784876 3 Q96QD8 1 +Phospholipid scramblase activity 0.7493341225214591 2.9640851556499395 0.0030358426429115 0.9853036880343912 0.0137255686917304 2 Q7Z3C6 1 +Oxidoreductase activity acting on single donors with incorporation of molecular oxygen 0.7478543947913614 2.9562834829520828 0.003113707612711 0.9868135912187174 0.0139670196035405 2 Q9BV57 1 +Mannosyl oligosaccharide mannosidase activity 0.8142140163175491 2.954723100909329 0.003129497908286 0.987100338110282 0.0139670196035405 3 P33908 1 +Organic acid transmembrane transporter activity 0.6545265332641447 2.942959421237813 0.0032509102698035 0.9891067709515018 0.0144623828669463 24 Q9H2D1,P53985,Q96NB2,Q02978,Q9Y619,Q9BQT8,O95563,Q9UBX3,P30825,Q9H936,Q9Y289,O75746,Q9H9B4,Q96QD8,P08195,P08183,Q15758 17 +Wide pore channel activity 0.8762709104185928 2.928480630424927 0.0034062305504045 0.991225613317106 0.0149615443163339 4 P45880,P21796 2 +Porin activity 0.8762709104185928 2.928480630424927 0.0034062305504045 0.991225613317106 0.0149615443163339 4 P45880,P21796 2 +Phospholipid binding 0.4289212242227267 2.910647124128402 0.0036068111324893 0.9933643850037692 0.0157429366411801 95 P50897,Q14108,P21796,Q9BWH2,Q96L92,Q9H4A5,P31749,P45880,O43633,Q9H4A6,P07602,O60749,Q9UM22,Q9Y5X3,O14773,Q8WTV0,Q9NZJ7,P20073,O43292 19 +Hydrolase activity acting on glycosyl bonds 0.5852324156982456 2.9061784102224255 0.0036587277213768 0.9938273490623862 0.0159194798660536 34 Q9NUJ1,P04062,P33908,P04066,P16278,O60502,P10253,O60476,Q9BTY2,P06865,Q8IW92,O75503,P17900,P54802,P06280 15 +Snap receptor activity 0.7452451005967232 2.899460041977272 0.0037380598712715 0.9944732130885012 0.0160136638929779 16 Q9P2W9,Q13277,O95721,O15400,O15498,Q13190,O60499,O95249,Q12981,O43752 10 +Calcium channel inhibitor activity 0.7330571174903853 2.877846059982222 0.0040040047521281 0.9961846185434606 0.0169955920365561 2 Q9NWR8 1 +Aspartic type peptidase activity 0.8634292226646355 2.869916001713899 0.0041058085327092 0.9966892932214252 0.0173745800103672 4 Q8TCT8,Q8TCT9 2 +Nadh pyrophosphatase activity 0.7951690647211427 2.8613305302192034 0.0042186697770327 0.9971711916598772 0.017743980759156 3 Q9BQG2 1 +Solute cation antiporter activity 0.7948935006262275 2.859971242438237 0.0042367942587375 0.9972417623216256 0.0177663759248572 3 O95202 1 +Protein transporter activity 0.7551722114277315 2.8540395685397137 0.0043167154414318 0.9975325508329376 0.0180469910623717 15 O60830,Q9NS69,O14925,Q99595,Q9HD20,Q15388,Q9Y5J9 7 +Sterol transfer activity 0.8594921965954041 2.851875905663554 0.0043462064067367 0.9976319345445932 0.0181157191968487 4 P30536,Q14849 2 +Secondary active transmembrane transporter activity 0.6485329722433046 2.8314442463313028 0.0046338311382345 0.998414262459889 0.0189123528565968 22 P12235,P53985,P12236,Q02978,O95202,Q9UBX3,Q9Y6M7,Q9H936,Q9Y289,P51798,Q96QD8,Q15758,P51790 13 +O acetyltransferase activity 0.7224030778336823 2.8208928306150542 0.0047890198818296 0.9987228538822804 0.0194361391695309 2 Q8NF37 1 +Amyloid beta binding 0.7644139073007044 2.8096478845877577 0.0049595727981137 0.9989932362150984 0.019838291192455 14 O00264,P10909,Q9NQX7,O15212,Q8WTV0,Q9Y287 6 +L serine transmembrane transporter activity 0.7844878626406211 2.8084747114026047 0.00497767916857 0.99901834575208 0.0198535019711932 3 Q9H9B4,Q96QD8 2 +Ceramide binding 0.8948459715639775 2.7665857654249573 0.0056646682365923 0.9996236207826464 0.0220239762251827 5 Q9UM22,P45880,P21796,P07602 4 +Glycosphingolipid binding 0.8388554315860977 2.7566530612402245 0.0058396274778946 0.9997051847728148 0.0223289337171289 4 Q9UM22,P07602 2 +Calcium ion binding 0.4170205888495651 2.75009093295915 0.0059578728677796 0.9997500526400328 0.0226047788461857 95 Q99584,O43852,Q9BQT9,Q9BPX6,P80303,P67936,P16615,Q9NWM8,Q8WVQ1,O95302,O60476,Q9Y680,Q14574,P41208,Q8TAB3,P0DP25,Q9UM22,P55327,P33908,Q96D71,Q96A33,Q14257,O95202,Q9H223,P20073,P22413,O43681,Q8IYU8 28 +Floppase activity 0.772633323593114 2.7494056503929367 0.00597034481875 0.9997543677734992 0.0226047788461857 3 P08183 1 +Arylesterase activity 0.7084936371707645 2.7459263149317987 0.0060340314308899 0.999775268893342 0.0227587924621611 2 Q15165 1 +Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.7699822380106605 2.736136731772132 0.0062165189725864 0.9998258266882528 0.0231949686396505 3 O95864,O75845 2 +Acid phosphatase activity 0.833780231122931 2.7330631669226917 0.0062748297018253 0.9998394497651484 0.0233497684346745 4 Q9NPH0 1 +Nucleobase transmembrane transporter activity 0.7034625628884326 2.718638734047343 0.0065551159694738 0.9998914666212098 0.0240065988539043 2 P12235 1 +Oxidative phosphorylation uncoupler activity 0.7034625628884326 2.718638734047343 0.0065551159694738 0.9998914666212098 0.0240065988539043 2 P12235 1 +Procollagen proline 4 dioxygenase activity 0.7657491693883676 2.714904874129991 0.0066294809875582 0.9999021775446454 0.0241514950412882 3 P13674 1 +Peptidyl proline 4 dioxygenase activity 0.7657491693883676 2.714904874129991 0.0066294809875582 0.9999021775446454 0.0241514950412882 3 P13674 1 +Beta n acetylhexosaminidase activity 0.8294366064606332 2.71281940747607 0.0066713453055629 0.9999077356842732 0.0242403855605269 4 P17900,P06865 2 +Palmitoyl protein hydrolase activity 0.8823259908937914 2.7114987002437374 0.0066979803656612 0.9999111064843528 0.0242736207507515 5 Q9NUJ1,Q9UMR5,P50897 3 +Serine hydrolase activity 0.6759067023566168 2.703576800874813 0.0068597593551349 0.9999290938350218 0.0246029612013625 18 P10619,P53634,Q16740,P67812,Q4J6C6,Q9H3G5,P42785,Q9HB40,O43464,O14773,O75976 11 +Glycolipid binding 0.8214400159816571 2.69949451353603 0.0069444900812332 0.9999370126595856 0.0247152621352607 10 Q9UM22,P50897,P07602,O43292,O14773 5 +Phosphatidyl phospholipase b activity 0.6957679786919249 2.6767265671161544 0.0074345280833338 0.9999682518175078 0.0262573154698917 2 Q8IY17 1 +Long chain fatty acid binding 0.6939923054158075 2.667023793615662 0.0076526253825237 0.9999765981404972 0.0269589950023933 2 Q13277 1 +2 acylglycerol 3 phosphate o acyltransferase activity 0.7548845470692735 2.660156668133862 0.0078104311639399 0.999981233480696 0.0273505843416824 3 Q96N66,Q92604 2 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.8177617759093865 2.658158601589232 0.0078568908633755 0.9999824144211829 0.0274004133627269 4 Q9UHG3 1 +Endopeptidase activity 0.4485086179802526 2.6365949710740155 0.0083742754781381 0.9999914743983828 0.0286466874213122 68 P28074,Q16740,P07858,P42892,Q92905,P53634,Q99538,Q6P179,Q96K76,Q4J6C6,Q9BXS4,Q9NZ08,P67812,Q8TCT9,O75844,O14773,O43464,P28072,Q8TCT8,Q92542,P22695,Q10713,O43292,P78536 24 +Primary active transmembrane transporter activity 0.4807880710242664 2.6361982920690745 0.0083840721477141 0.9999915905092996 0.0286466874213122 57 P05023,Q9UDW1,P20674,O75438,O43676,P06576,O75306,P00403,P16615,P51798,O95298,P13073,P98194,P28288,P61421,O75489,P03886,Q9HD20,P10606,Q15388,P08183 21 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.5492944749911421 2.6355541863649545 0.0084000012827623 0.9999917759387308 0.0286466874213122 35 P13674,Q9BU89,Q6PK18,Q32P28,P16435,Q6UW02,P09601,O15460,P30519,O75845,Q16850,P61457,Q15800,Q14534 14 +Voltage gated chloride channel activity 0.7495559502664245 2.633170667575931 0.0084591828726952 0.9999924297826092 0.0286611187347894 3 P51798,P51790 2 +Syndecan binding 0.6877774489493974 2.632972929371894 0.0084641093247421 0.9999924818092654 0.0286611187347894 2 Q9Y251 1 +Thiol oxidase activity 0.7490939430597902 2.630826702586944 0.0085177457310574 0.9999930256394712 0.0286611187347894 3 Q6ZRP7 1 +Structural constituent of eye lens 0.7471282661680412 2.6208464778772136 0.0087711750842052 0.9999951089186748 0.0292704824445699 3 P08670 1 +Hexosaminidase activity 0.860290609479312 2.6136383142742994 0.0089583815173226 0.9999962368859086 0.0296759750502239 5 P17900,P06865,P54802 3 +Macromolecule transmembrane transporter activity 0.7566224838832435 2.5961466569894087 0.0094275815978588 0.99999804975573 0.0310082541654693 12 P51991,O60830,Q9NS69,P49755,O14925,Q99595,Q07820,Q15388 8 +Organic cation transmembrane transporter activity 0.8042641397690193 2.594507116457649 0.0094726652537306 0.9999981691478332 0.0310338030869678 4 Q70HW3,Q99808,O43808 3 +Peroxisome targeting sequence binding 0.7391205384872268 2.5800637173320315 0.0098782086986146 0.999998962942106 0.031862262150739 3 P40855 1 +Serine type carboxypeptidase activity 0.8525568865835298 2.579015819886138 0.0099082248975441 0.9999990056748594 0.031862262150739 5 P10619,Q9HB40,P42785 3 +Metal ion transmembrane transporter activity 0.6022281824396367 2.5783908496390104 0.0099261653367623 0.9999990303710216 0.031862262150739 24 P16615,P05023,O95202,P05026,Q9Y6M7,Q6P4Q7,P98194,Q9HD20,Q9Y289,Q9HC07,Q9H0U3,Q96QD8 12 +Protein transmembrane transporter activity 0.7678783507413445 2.577918623467859 0.0099397402818948 0.9999990486496052 0.031862262150739 11 O60830,Q9NS69,P49755,O14925,Q99595,Q15388 6 +Inorganic anion transmembrane transporter activity 0.6373774777185114 2.572922643255412 0.0100843744674754 0.999999223264467 0.0321772684157607 19 P45880,Q9Y6M7,Q9UBX3,Q9C0H2,P21796,O43681,Q9Y277,Q96S66,P0CG08,P51790 10 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.7918232796142244 2.5354020924403837 0.0112318320730397 0.9999998447136452 0.0350332200390544 4 P46977,P04843 2 +Cargo receptor activity 0.7594184652394789 2.534011250401363 0.0112765111250074 0.9999998541541162 0.0350937162365704 11 Q8WTV0,Q14108,O15260 3 +Monooxygenase activity 0.8132677577898588 2.522527619694639 0.0116514799881253 0.9999999138527554 0.0359383427189287 9 Q9BU89,Q6UW02,P09601,P30519,Q16850,Q15800,Q14534 7 +Polypeptide n acetylgalactosaminyltransferase activity 0.7261693309650715 2.5136753532074296 0.0119480363654349 0.9999999432007736 0.0366089944265424 3 Q10471,Q10472 2 +Acetylgalactosaminyltransferase activity 0.7261693309650715 2.5136753532074296 0.0119480363654349 0.9999999432007736 0.0366089944265424 3 Q10471,Q10472 2 +Phosphatidylcholine binding 0.8634400967410485 2.5093836834696734 0.0120942039221558 0.9999999537448128 0.036813059306913 7 P21796,Q14108 2 +Serine transmembrane transporter activity 0.7847201658276521 2.5014668589456344 0.0123680017540528 0.9999999685173544 0.037548630502664 4 Q9H9B4,Q96QD8,Q96NB2 3 +Mhc class ib protein binding 0.7203730430266244 2.483790818992904 0.0129992142554171 0.9999999870375292 0.0391386320748785 3 Q9NUQ9 1 +Anion channel activity 0.7311359610522197 2.460012695700751 0.0138932101019293 0.9999999963149664 0.0411167923698889 12 P45880,Q9C0H2,P21796,Q9Y277,Q96S66,P0CG08,P51790 7 +Fad binding 0.7930898007391047 2.425322984888382 0.0152947725995697 0.9999999994882406 0.0445055437488529 9 Q15067,O15254,O95831,Q15392,Q14534 5 +Glycolipid mannosyltransferase activity 0.7079988721759288 2.419633196767299 0.0155361697377325 0.999999999635856 0.0450192141878345 3 Q2TAA5 1 +Flippase activity 0.7062971432129842 2.4107717465204916 0.0159188074751848 0.999999999787708 0.046031884949076 3 P08183 1 +P type calcium transporter activity 0.7048549437536874 2.403254483398002 0.0162498746403725 0.9999999998669228 0.0466008801670187 3 P16615,P98194 2 +Protein lipid complex binding 0.8088353180018353 2.3805433418130724 0.0172871272813637 0.999999999969226 0.0487915833220401 5 Q9BQE5 1 +Cytoskeleton nuclear membrane anchor activity 0.7004144464180057 2.3800671200728885 0.0173094848695969 0.9999999999701826 0.0487915833220401 3 Q9UH99,O94901 2 +Nucleobase containing compound transmembrane transporter activity 0.7162462746455855 2.379470678247674 0.0173375223000591 0.9999999999713404 0.0487915833220401 12 P51991,Q9H2D1,Q99808,P12236,Q8TB61,Q6NUK1,Q9BSK2,O43808,L0R6Q1 9 +Neurexin family protein binding 0.6422018348623904 2.378880507152821 0.0173653041506396 0.9999999999724432 0.0487915833220401 2 O00560 1 +Ubiquinone binding 0.6410180526783125 2.3721768750624133 0.0176836230860586 0.999999999982424 0.04958559362313 2 P21912 1 +Sphingolipid binding 0.8323238992686864 2.369938408646308 0.0177910487077153 0.9999999999848992 0.0497862411417517 7 Q9UM22,P45880,P21796,P07602 4 +Lysophospholipid acyltransferase activity 0.7551080840983075 2.3585021145696796 0.0183488552496877 0.9999999999931364 0.0512438854860495 4 Q96N66,Q92604,Q86UL3 3 +Mannosidase activity 0.7485052673506131 2.3262944924200495 0.0200028456457839 0.9999999999993392 0.055196719197511 4 P33908 1 +Scavenger receptor activity 0.8447036549863768 2.3184590860644647 0.0204243840674838 0.9999999999996364 0.0556955699129028 6 Q8WTV0,Q14108 2 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 0.7943354470799551 2.3136853718224737 0.0206849868792788 0.9999999999997486 0.0560757066180451 5 O15254,Q15067 2 +Camp dependent protein kinase regulator activity 0.6869095830200092 2.3091583652076997 0.02093479498277 0.9999999999998236 0.0565320922881028 3 P54619 1 +Gated channel activity 0.688581774555657 2.3038443680805236 0.0212313815201226 0.9999999999998842 0.0572216651454954 13 P45880,Q9C0H2,P21796,Q9Y277,P0CG08,P51790 6 +Serine type exopeptidase activity 0.8147039513160207 2.2899616134393694 0.0220235419894945 0.9999999999999624 0.0591270334263411 7 P10619,Q9HB40,O14773,P42785 4 +Hexosyltransferase activity 0.5058463208183797 2.2871348455160248 0.022187953553411 0.99999999999997 0.0593388815648065 36 P46976,O60762,Q8TCJ2,P46977,Q10472,O75340,P04062,Q16880,P07686,Q13126,O43505,Q9BT22,Q16739,Q9Y2G5,P06865,P04843,Q10471,Q2TAA5 18 +Amino acid transmembrane transporter activity 0.7105459040885608 2.275870382984098 0.0228537686047527 0.9999999999999885 0.0607682582823693 11 Q96NB2,Q9Y619,P30825,Q9H936,O75746,Q9H9B4,Q96QD8,Q15758,P08195 9 +Signaling receptor regulator activity 0.5923196559809423 2.273322022936746 0.0230067813386556 0.9999999999999908 0.0609416269046832 19 Q92520,Q9UMX5,P05067,P43490,P14174 5 +Quaternary ammonium group binding 0.6959625245461668 2.268541940363499 0.0232961957680302 0.9999999999999938 0.0615907042400494 12 P21796,O43633,Q14108,P45880 4 +Oligosaccharyl transferase activity 0.782828951747842 2.260260605564594 0.0238050814109558 0.999999999999997 0.0626851200046065 5 P46977,P04843 2 +Aminophospholipid flippase activity 0.6197099733649063 2.250606785511459 0.0244104532726479 0.9999999999999988 0.0636874232000663 2 Q9NV96 1 +Voltage gated anion channel activity 0.8018929356818746 2.231350776401122 0.0256579027007106 0.9999999999999998 0.0663981968725226 7 P45880,P21796,Q9Y277,P0CG08,P51790 5 +Quinone binding 0.7757413207097204 2.227190154694913 0.0259345678415312 1.0 0.0669092568104932 5 Q8N0U8 1 +Sterol transporter activity 0.747387089150046 2.2010363837507456 0.0277334482197761 1.0 0.0701825687315804 9 O15118,P30536,Q14849 3 +Sulfur compound transmembrane transporter activity 0.8164073393598277 2.1934409103733006 0.0282756275169029 1.0 0.0712278965398571 6 Q70HW3,Q9UBX3 2 +Acidic amino acid transmembrane transporter activity 0.7201658276576794 2.1866900768444184 0.0287651565075148 1.0 0.071907535785582 4 Q15758,O75746,Q9H936 3 +L aspartate transmembrane transporter activity 0.7201658276576794 2.1866900768444184 0.0287651565075148 1.0 0.071907535785582 4 Q15758,O75746,Q9H936 3 +Protein carrier chaperone 0.6911413826057426 2.171237870972773 0.0299131960037115 1.0 0.0738781424433303 11 Q9P0I2,Q15070,Q8N8Q8,Q5J8M3,Q9NPA0,P10909,P40855,Q9Y5J7 8 +Atpase coupled intramembrane lipid transporter activity 0.7161227281936624 2.166592532705278 0.0302659372850351 1.0 0.0744842570064339 4 Q96AA3,P08183 2 +Glucosyltransferase activity 0.7138285556796808 2.1567074422326393 0.0310284667532072 1.0 0.0759568110290152 10 Q16739 1 +Proton channel activity 0.6836144340405352 2.1303238031292455 0.0331448897021495 1.0 0.0800088815766671 11 P36542,P24539,P00846,P56134,P06576,O75964 6 +Proton transporting atp synthase activity rotational mechanism 0.6836144340405352 2.1303238031292455 0.0331448897021495 1.0 0.0800088815766671 11 P36542,P24539,P00846,P56134,P06576,O75964 6 +Oxidoreduction driven active transmembrane transporter activity 0.4993267001862438 2.1277574801797177 0.033357196414256 1.0 0.0803815774704642 32 O95298,Q9Y6M9,P56556,P13073,O75489,O43674,Q9UDW1,P03886,P20674,O95168,P10606,P51970,O75438,O43676,O75306,O14548,P00403 17 +Peptidyl proline dioxygenase activity 0.7529620853080489 2.120067078689861 0.0340003888030522 1.0 0.0810868379014372 5 P13674,Q8IVL6,Q32P28,O15460 4 +Procollagen proline dioxygenase activity 0.7529620853080489 2.120067078689861 0.0340003888030522 1.0 0.0810868379014372 5 P13674,Q8IVL6,Q32P28,O15460 4 +Iron ion binding 0.5263928283567505 2.116922199147603 0.0342664512872608 1.0 0.0815811910578353 27 P13674,Q9BU89,Q6PK18,Q32P28,Q6UW02,O15460,Q9BV57,P22830,O75845,Q16850,Q15800 11 +Phosphatidylserine binding 0.7054143505507722 2.1128214699539924 0.0346160513178337 1.0 0.0822723959403308 10 Q14108 1 +Potassium ion transmembrane transporter activity 0.7041136627525558 2.106633032112496 0.0351494011651878 1.0 0.083113064424669 4 P05026,P05023 2 +Adp transmembrane transporter activity 0.7038791827065382 2.105458380563573 0.0352514265256906 1.0 0.0832125510504399 4 P12235,P12236,O43808 3 +Organophosphate ester transmembrane transporter activity 0.7012545555684809 2.0910479900398893 0.0365237622750933 1.0 0.0856334156044418 10 Q9H2D1,Q99808,P12236,Q8TB61,Q6NUK1,Q9BSK2,O43808 7 +Nucleotide transmembrane transporter activity 0.7012545555684809 2.0910479900398893 0.0365237622750933 1.0 0.0856334156044418 10 Q9H2D1,Q99808,P12236,Q8TB61,Q6NUK1,Q9BSK2,O43808 7 +Phosphotransferase activity for other substituted phosphate groups 0.7460552971775795 2.087335907699329 0.0368577811007115 1.0 0.0862708265898611 5 Q9H9S5,Q9BVG9 2 +L amino acid transmembrane transporter activity 0.7212336892052389 2.0701126742133256 0.0384417942782517 1.0 0.0893755619065552 9 Q9Y619,P30825,Q9H936,O75746,Q9H9B4,Q96QD8,Q15758,P08195 8 +Palmitoyltransferase activity 0.7410245388346117 2.0634222413426224 0.0390725286070672 1.0 0.0906900831214202 5 P50416,O15498,O15269 3 +Voltage gated channel activity 0.670722429433629 2.059823924827103 0.0394153765085831 1.0 0.0911809043231891 11 P45880,P21796,Q9Y277,P0CG08,P51790 5 +Clathrin heavy chain binding 0.7373703485318139 2.0460136751497493 0.0407550252398554 1.0 0.0933464934536622 5 Q5VW38 1 +Sodium ion transmembrane transporter activity 0.7144455768303838 2.0358275563180492 0.0417676743176063 1.0 0.0951946337485017 9 P05023,Q9Y6M7,P05026,Q6P4Q7,Q9Y289,P55011,Q96QD8 7 +Tap binding 0.7323570671489316 2.0220780358405097 0.0431682907124664 1.0 0.0979045547531101 5 P10321,P01889,P04439 3 +Dipeptidyl peptidase activity 0.6321641066079473 2.0157290416060425 0.0438283170604347 1.0 0.0990776939411782 3 P42785 1 +Exogenous protein binding 0.5841068785569089 2.0150401106169245 0.0439004465029904 1.0 0.099079381701058 17 O15118,Q14108,P35613,P11279,P06493,Q8WTV0 6 +P type transmembrane transporter activity 0.7302654414750982 2.012073840064091 0.0442121538188384 1.0 0.0996208920463438 5 P16615,P98194,P05023 3 +Oxidoreductase activity acting on a heme group of donors 0.7751111111110827 2.007826470082956 0.0446617349644664 1.0 0.1000158006216873 6 P13073,P16435,P20674,P10606,P00403 5 +Neutral amino acid transmembrane transporter activity 0.7280805687203719 2.0016124653769163 0.0453264272995665 1.0 0.1011464326234701 5 Q9H9B4,Q96QD8,Q15758,Q96NB2 4 +Solute sodium symporter activity 0.7156882233689366 1.9420620977007348 0.0521295832335291 1.0 0.1141259645554233 5 Q9Y289,Q9Y6M7,Q96QD8 3 +Membrane insertase activity 0.714380541416954 1.9229114258318192 0.0544911745770508 1.0 0.1183626765460823 8 Q9P0I2,Q15070,Q8N8Q8,Q5J8M3,Q9NPA0,Q9Y5J7 6 +Calcium channel regulator activity 0.6623214552633422 1.894934511003621 0.0581010783624607 1.0 0.1246434262242588 4 P62258,Q9NWR8 2 +Sodium channel regulator activity 0.6620244317145869 1.8934134322702625 0.0583029105171362 1.0 0.1248833947496683 4 P46934 1 +Udp glycosyltransferase activity 0.5645587886079483 1.8867892423848256 0.0591886786186748 1.0 0.1264258753257793 17 Q10472,Q16880,P07686,O43505,P06865,Q16739 6 +Atp transmembrane transporter activity 0.7040876777251124 1.8859901211489023 0.0592962859056789 1.0 0.1264258753257793 5 P12235,Q6NUK1,P12236,O43808 4 +Peptide antigen binding 0.7429891583857297 1.8609140390880583 0.0627563168761817 1.0 0.1319784360971822 6 P10321,P01889,Q15392 3 +Cation channel activity 0.517795507350031 1.8588022522514576 0.0630551731156705 1.0 0.1324063241823762 20 P36542,P24539,P00846,P56134,P06576,O75964 6 +Peptidase activity 0.348875986724319 1.855493136054313 0.0635258385017456 1.0 0.1330811033627547 117 P10619,P28074,Q16740,P07858,P42892,Q92905,P55786,Q9HB40,P53634,P36551,Q99538,Q6P179,Q96K76,Q4J6C6,Q9BXS4,Q9NZ08,P83111,P67812,Q8TCT9,Q9BT78,Q96FZ2,O75844,O14773,Q9UIQ6,O43464,P28072,O75976,Q8TCT8,Q92542,P22695,Q10713,O43292,Q9H3G5,P78536,P42785 35 +Chaperone binding 0.4449808701118801 1.855195744211839 0.0635682791999325 1.0 0.1330811033627547 44 Q9UL15,O95433,P05023,Q14108,Q96KC8,P53634,P01889,Q16543,O43808,P10909,O43615,O15212,Q9Y5J7 13 +Acylglycerol o acyltransferase activity 0.6963862559241644 1.848593621495402 0.0645165144272532 1.0 0.1340360416294427 5 Q8NF37,Q96N66,Q92604,Q86UL3 4 +Antiporter activity 0.6550870502406491 1.84602253250558 0.0648889338001432 1.0 0.1344266270367147 10 P12236,Q02978,O95202,Q9UBX3,P51798,P51790 6 +Growth factor receptor binding 0.5572778592681097 1.8385981649173408 0.0659743113983144 1.0 0.1360658903727495 17 Q92542,P05067,Q8WXW3,Q3ZCQ8,Q9H2J4,O60749,Q9NZ08 7 +Cytokine activity 0.7172829650931674 1.8346275231145557 0.0665608977331293 1.0 0.1368689274867904 7 P43490,P14174 2 +Histone h3 tri di monomethyl lysine 4 demethylase activity 0.5474992601361417 1.826054527487926 0.0678420487802264 1.0 0.1390912314726061 2 Q9H6W3 1 +Ubiquitin ligase substrate adaptor activity 0.6465610191616692 1.8139137658735336 0.0696910030527293 1.0 0.1424611373154467 4 Q9Y297,O75340 2 +Amide binding 0.3470242026934118 1.8093213095965188 0.0704011002780238 1.0 0.1437010693910251 111 P24390,P01889,P21796,P42892,O43731,Q9NQX7,P55786,P40855,P45880,O00264,Q6P179,P07602,Q9Y680,O15212,P09496,Q9UHV9,Q9NZ08,Q9Y287,Q9UM22,Q92973,Q99735,P10909,Q9UIQ6,O14773,Q8WTV0,Q15392,P48637,Q9NZJ7,P00374,Q15388 30 +Lipid transfer activity 0.6906541311275662 1.8054268375262208 0.0710079146715729 1.0 0.1445146415896529 8 P30536,Q14849 2 +Carbohydrate derivative transmembrane transporter activity 0.668305039981487 1.799551623544129 0.0719314655855616 1.0 0.1459661903987712 9 Q99808,P12236,Q8TB61,Q6NUK1,O43808,L0R6Q1 6 +Collagen binding 0.6225921423792035 1.7920057328074237 0.0731320477030434 1.0 0.1479697991426011 11 O75718,Q32P28,P07858,Q92791,Q9UBG0 5 +Symporter activity 0.6444411840875902 1.7886688328109244 0.0736681652213575 1.0 0.1488375739843439 10 P53985,Q9Y6M7,Q9H936,Q9Y289,Q96QD8,Q15758 6 +Intramembrane lipid transporter activity 0.7233518649900703 1.7700557338530514 0.0767178566833015 1.0 0.1538791691855817 6 Q96AA3,P08183,Q7Z3C6,Q4KMQ2 4 +O acyltransferase activity 0.616491347099301 1.7575566393959852 0.0788229766462293 1.0 0.1571555454991051 11 P50416,Q96N66,O15228,Q92604,P35610,Q9HCL2,Q86UL3,P23786,Q8NF37 9 +C4 dicarboxylate transmembrane transporter activity 0.7205925925925707 1.7572279864062728 0.078878956800374 1.0 0.1571555454991051 6 Q02978,Q9UBX3,Q9H936,O75746,Q15758 5 +Glycosyltransferase activity 0.4182821034015361 1.7570021301480865 0.0789174461187869 1.0 0.1571555454991051 50 P46977,O60762,Q8TCJ2,Q10472,P04062,Q16880,Q13126,O43505,Q68CQ7,Q9BT22,Q16739,Q9Y2G5,Q8IXJ6,P06865,P04843,P43490,Q06203 17 +Atpase coupled transmembrane transporter activity 0.4883879200551131 1.7559894969627514 0.079090201963655 1.0 0.1572001769962057 25 P16615,P05023,P98194,Q9HD20,P51798,P06576,P28288,Q15388,P08183,P61421 10 +Mannose binding 0.7129472325938853 1.721608628314087 0.0851404391214554 1.0 0.1669137422324578 6 O60762,P35613,P49257,O75503 4 +Metalloendopeptidase activity 0.5521851156708708 1.7197352677206084 0.085480573973798 1.0 0.1672862623930821 16 Q10713,P22695,P42892,O75844 4 +Mhc protein binding 0.6295769765741692 1.7080822979379555 0.0876210730522137 1.0 0.1708118671298774 10 Q9BUN8,P51572,Q9NUQ9 3 +Atpase coupled cation transmembrane transporter activity 0.574271913562694 1.7064316784468163 0.0879277367188013 1.0 0.1711692827008363 14 P16615,P05023,P98194,Q9HD20,P06576,P61421 6 +Vitamin transmembrane transporter activity 0.6819651507259392 1.664330943560508 0.0960463119128087 1.0 0.1841329847168212 7 Q9H2D1,P04062 2 +Thiolester hydrolase activity 0.5525273775455111 1.6437806457351123 0.1002215205902503 1.0 0.1895199784128852 15 Q9NUJ1,Q9UMR5,P50897 3 +Peptidase activator activity involved in apoptotic process 0.5643584354522883 1.6396004150081591 0.1010882767616152 1.0 0.1907676577019111 3 Q9BXK5 1 +Phosphatase activator activity 0.6497079453676271 1.6191731654281103 0.1054100100082111 1.0 0.1974481698939232 5 P35269 1 +Galactosyltransferase activity 0.6083818520849156 1.6151591268263 0.1062762393529452 1.0 0.1982680379326452 4 O43505 1 +Inositol tetrakisphosphate phosphatase activity 0.5105060668837008 1.6015757781357916 0.1092494506011183 1.0 0.2021843165791363 2 Q9UNW1 1 +Modified amino acid binding 0.4766192774867256 1.5918521610660146 0.1114179267319463 1.0 0.2053759393146634 22 Q8WTV0,Q99735,Q14108,P48637 4 +Rna strand annealing activity 0.6429994404064067 1.5858402866138268 0.1127755442931821 1.0 0.2070591044220586 5 P23588,O00571,Q06787 3 +Carboxypeptidase activity 0.5863491202855188 1.5858268636914092 0.1127785900166256 1.0 0.2070591044220586 11 P10619,Q9HB40,P42785,Q9H3G5 4 +Phosphoric diester hydrolase activity 0.5847469936895165 1.5766318740111376 0.1148802542224451 1.0 0.2106390922863328 11 P09601,Q8N2A8,Q8IV08 3 +Ubiquitin conjugating enzyme binding 0.6405350753679412 1.5531245938263434 0.120393371596684 1.0 0.2198763154949967 8 Q92564 1 +Chemokine binding 0.5022195915951518 1.5507383771285437 0.1209643935938136 1.0 0.2206288808255102 2 P09429 1 +Purine nucleotide transmembrane transporter activity 0.6367395565434583 1.5338118303472374 0.125075951715796 1.0 0.2245865730679493 8 Q99808,P12236,Q8TB61,Q6NUK1,O43808 5 +Immunoglobulin binding 0.4989641905889393 1.5307175384953318 0.1258392172686377 1.0 0.2253739787985409 2 P17931 1 +Glucosidase activity 0.6313082865281454 1.5275566503176683 0.1266226517330937 1.0 0.2264848461411521 5 P04062 1 +Lipid transporter activity 0.4581577745947996 1.515230375016681 0.1297140733241013 1.0 0.2312025695043534 25 O15118,P61916,P30536,Q14849,P17900 5 +Proteoglycan binding 0.6688700496231059 1.5142188753175625 0.1299703359283714 1.0 0.231280546498179 6 P07858,P10586 2 +Dicarboxylic acid transmembrane transporter activity 0.6319659543991741 1.50948567426957 0.1311747135356822 1.0 0.2326361165651118 8 Q02978,Q9BQT8,Q9UBX3,Q9H936,O75746,Q15758 6 +Nucleotide diphosphatase activity 0.5882805770341522 1.5092499200020355 0.1312349274283015 1.0 0.2326361165651118 4 Q9BQG2 1 +G protein beta subunit binding 0.5411014034713428 1.507774661128951 0.1316122094055705 1.0 0.2329251193049695 3 P63218 1 +Ccr5 chemokine receptor binding 0.4933412252145682 1.4960747792083806 0.1346341694032928 1.0 0.2371474963601148 2 P48681 1 +Nadplus kinase activity 0.4930452796685489 1.4942494012462662 0.1351104448364459 1.0 0.2376847876210228 2 Q53H12 1 +Protein kinase a catalytic subunit binding 0.6228364203580622 1.4851785300621867 0.1374965378078485 1.0 0.2409661546430477 5 P13861,P49841,P41240 3 +Protein homodimerization activity 0.3176582470021319 1.4817312690259965 0.1384118134924346 1.0 0.2419591903369007 177 P51648,Q9BRG1,Q14108,Q99584,P09493,P42892,Q8N2A8,O75874,P27105,P67936,P16278,P31749,O00264,P36551,P09601,P22830,Q9GZY8,Q8WVQ1,Q8TBA6,Q04837,P07602,O95772,Q14849,O60749,Q8IY95,Q9Y5J7,Q9UKU0,O75208,Q15067,P55327,Q8TCT9,Q07812,Q8NBZ7,Q8TCT8,P48637,Q9NZJ7,Q07820,Q9BW92,P22413,O95684,P06280 41 +Bh3 domain binding 0.5337974724473495 1.4661339232842987 0.1426118055658571 1.0 0.2459932283705402 3 Q07820 1 +Death domain binding 0.5337974724473495 1.4661339232842987 0.1426118055658571 1.0 0.2459932283705402 3 Q07820 1 +Bh domain binding 0.5337974724473495 1.4661339232842987 0.1426118055658571 1.0 0.2459932283705402 3 Q07820 1 +Signal sequence binding 0.4410727716091036 1.4553846653231204 0.14556279930212 1.0 0.250050947316018 28 O43731,Q15388,P24390,P40855 4 +Isocitrate dehydrogenase activity 0.6165657392515493 1.4537394324587989 0.1460185612404818 1.0 0.2505238108798378 5 P48735 1 +Acetylglucosaminyltransferase activity 0.6163265094095707 1.4525388660290923 0.1463518305064499 1.0 0.250785605855497 5 O43505,P06865 2 +Nedd8 specific protease activity 0.5308592356890285 1.4493539225063488 0.14723876952575 1.0 0.2519943429121344 3 Q92905 1 +Mitochondrial ribosome binding 0.6135074216045808 1.4383852425045471 0.1503247775020151 1.0 0.2550743168371601 5 Q92552,Q15070,Q9BSH4 3 +Solute cation symporter activity 0.6147538512719601 1.4214584585026513 0.1551835220878357 1.0 0.2601385611810579 8 Q9Y289,Q9Y6M7,Q96QD8,Q9H936 4 +Nadh dehydrogenase activity 0.4448365160353985 1.385090339457814 0.1660248454931334 1.0 0.2756489061536713 24 O95298,Q9Y6M9,P56556,O75489,O43674,P03886,O95168,O95831,O75438,O43676,P51970,O75306 12 +Signal recognition particle binding 0.637389033449821 1.3642990910950878 0.1724734518541728 1.0 0.2843149063819381 6 Q9BUN8,Q9GZP9 2 +Carbohydrate binding 0.3805051702221392 1.32621621860576 0.1847680886328675 1.0 0.3010408774373916 49 P13674,O60762,Q6PK18,Q10472,Q32P28,O15460,P35613,P08236,Q9NPA0,P10253,P22413,Q13438,P49257,Q9UBG0,O75503,P52789 16 +G quadruplex rna binding 0.5088809946714143 1.32339582070688 0.1857037809071644 1.0 0.3021768439614821 3 Q8IZH2,Q06787 2 +Protease binding 0.4268466679665531 1.308254456259609 0.1907870170884575 1.0 0.3082983121745017 27 Q9GZP9,Q9NZJ7,Q9BUN8,P07602,P14174 5 +Exopeptidase activity 0.4150394941730689 1.3075997283051497 0.1910091091157528 1.0 0.3082983121745017 30 P10619,P36551,Q6P179,Q9H3G5,P55786,Q9UIQ6,O75844,Q9HB40,O14773,P42785 10 +Mhc class i protein binding 0.5751450919439577 1.3075659625016711 0.1910205680620111 1.0 0.3082983121745017 9 Q9BUN8,P51572 2 +Monocarboxylic acid transmembrane transporter activity 0.5869890494774173 1.304764523169737 0.1919730428798156 1.0 0.3094757067563114 5 Q9Y289,P53985 2 +Nitric oxide synthase regulator activity 0.5852061873348386 1.2957552140521782 0.1950598322420904 1.0 0.313012950721888 5 P31749 1 +Calmodulin dependent protein phosphatase activity 0.4590115418763005 1.2832118007341256 0.1994178827531552 1.0 0.318804443563162 2 Q08209 1 +Syntaxin binding 0.4388697651598832 1.2820715747251883 0.1998175393250036 1.0 0.318804443563162 21 P49755,O95721,Q9BVK6,O60499,O43752 5 +L ascorbic acid binding 0.5703868050190881 1.282044624217817 0.1998269927233076 1.0 0.318804443563162 9 P13674,Q32P28,O15460 3 +Protein arginine omega n asymmetric methyltransferase activity 0.5014801657785829 1.280842395210849 0.20024902954705 1.0 0.318928921787647 3 Q86X55,Q99873 2 +Protein disulfide isomerase activity 0.533240714260556 1.2780877950645158 0.2012184718468845 1.0 0.3199212358802701 11 Q6ZRP7,Q9BS26,P07237,Q96JJ7 4 +Frizzled binding 0.4991119005328752 1.2672148261594611 0.2050784858552772 1.0 0.3235463533010794 3 O00560,O14641 2 +Atpase binding 0.4093755727702569 1.257669276896375 0.2085113877431978 1.0 0.327391183470089 30 Q9NWS0,Q92542,Q16740,P05026,O76024,P00533,Q93050,Q9BUN8,P40855,P54709,Q9UII2,Q9Y487 12 +Lysophospholipase activity 0.5397410999717238 1.2508727678250822 0.2109809007310767 1.0 0.3308943392256888 4 Q8N2K0 1 +Structural constituent of muscle 0.6117608936190267 1.2414921781504007 0.2144239859071022 1.0 0.3342629142832646 6 P09493,P67936 2 +N6 methyladenosine containing rna binding 0.6116764586781822 1.241086836201568 0.2145736719210293 1.0 0.3342629142832646 6 P22626,Q9H6S0,P07910 3 +Tumor necrosis factor receptor binding 0.4934872705743253 1.23483361131727 0.2168924354208412 1.0 0.3367412755750869 3 Q9NXR7,Q12931 2 +Tumor necrosis factor receptor superfamily binding 0.4934872705743253 1.23483361131727 0.2168924354208412 1.0 0.3367412755750869 3 Q9NXR7,Q12931 2 +Mannosyltransferase activity 0.6084294058363799 1.2254963645922747 0.2203882589857251 1.0 0.3417207767618296 6 Q2TAA5,O60762,Q9BT22 3 +Lys63 specific deubiquitinase activity 0.4495412844036784 1.2242177624008803 0.2208700902557938 1.0 0.3417207767618296 2 O00487 1 +Intramolecular oxidoreductase activity transposing c c bonds 0.5764548406047054 1.2242082202008453 0.2208736889965483 1.0 0.3417207767618296 8 Q15125 1 +Electron transfer activity 0.3576226345391013 1.2226505601266249 0.2214617078334813 1.0 0.3417207767618296 54 O43674,Q9UDW1,P14406,P20674,O75438,O43676,O75306,P00403,P16435,O43175,P21912,O95168,O95298,Q9Y6M9,P13073,P56556,O15460,O75489,P03886,P10606,O14548 21 +Calcium ion transmembrane transporter activity 0.5057553221889074 1.2194816509673396 0.2226614360568517 1.0 0.3422461533434818 13 P16615,Q00535,P20020,O95202,Q8NE86,P98194,Q9HC07,P08195 8 +Transferase activity transferring sulphur containing groups 0.5752176367475412 1.2178148081846758 0.2232943557307094 1.0 0.3424669234853312 8 Q8NCH0 1 +Gtp dependent protein binding 0.5581605474969457 1.2163752653174995 0.2238420019063318 1.0 0.3429279234503185 9 P61020,Q9BZG1,Q86YV9 3 +Misfolded protein binding 0.4944945637085118 1.207059594843669 0.227409193988364 1.0 0.3468614958855486 14 P10909,Q9BUN8,Q9GZP9,P48723 4 +Dynein heavy chain binding 0.4857904085257676 1.1904981674977162 0.2338506498295953 1.0 0.3545020565311854 3 O43237,Q13409 2 +Molecular carrier activity 0.3858335835708605 1.1675333742660547 0.2429950385686627 1.0 0.3658103183658394 34 Q9P0I2,O15504,O75880,Q92973,Q8N8Q8,Q9C0E2,Q5J8M3,Q9NPA0,P10909,O14980,P40855,Q9Y5J7 12 +Oxidoreductase activity acting on nad p h 0.3904004978788944 1.163789924020178 0.2445091564736965 1.0 0.3676909091933811 32 P16435,O75489,P03886,O95831,O75438,O43676,Q13423,O75306 8 +Exodeoxyribonuclease activity 0.5287893724750967 1.1493704852718891 0.2504032449600115 1.0 0.3749295620328975 10 Q8IV08 1 +Fibroblast growth factor binding 0.5536671624994343 1.1361041279607649 0.2559129876275645 1.0 0.3815330041106977 5 Q92896 1 +Copper ion binding 0.5404499069029258 1.1211073743167534 0.2622421600950282 1.0 0.3888804681751059 9 O60888,O75880,P00403 3 +Protein phosphatase 2a binding 0.5397110810363238 1.117131963813963 0.263937905499223 1.0 0.3905605680521551 9 O43768,O43815,P78318,P18031,Q86XL3 5 +Antigen binding 0.5546063678576783 1.1112321435388446 0.2664684387755904 1.0 0.3938486075728992 8 P10321,P01889,Q15392 3 +Structural constituent of postsynapse 0.5430863899861704 1.082527631903045 0.2790181441204173 1.0 0.408520236328206 5 P07196 1 +Lipase binding 0.4261615862681357 1.078526570220476 0.2807988308581006 1.0 0.4106941804331335 2 P30533 1 +Snare binding 0.3807781395000957 1.0753894650493778 0.2822003964359036 1.0 0.4110996540698916 32 Q13277,O95721,P49755,O15400,Q9BVK6,Q13190,O60499,O43752 8 +Dioxygenase activity 0.4061198269159859 1.0558164159737318 0.2910520967785119 1.0 0.4208128232589319 23 P13674,Q9NVH6,Q6PK18,Q32P28,P16435,P07237,Q9BV57,Q8IVL6,O15460 9 +Phosphatidylinositol 4 phosphate binding 0.5256588979545397 1.0415487997649444 0.2976209170643358 1.0 0.4285247229100603 9 Q9H4A5,Q9H4A6,Q9Y5X3 3 +Calcium dependent protein serine threonine phosphatase activity 0.4591474245115523 1.037116105906718 0.2996817499879145 1.0 0.4298871041864275 3 Q08209,Q13555 2 +Protein dimerization activity 0.289204139393675 1.0050529216862625 0.3148713675947137 1.0 0.4500941897234424 231 P51648,Q9BRG1,P05023,Q14108,Q99584,P09493,Q9BPX6,P42892,Q8N2A8,O75874,P27105,P67936,P16278,P31749,O00264,P36551,P09601,P22830,Q9GZY8,Q8WVQ1,Q8TBA6,Q04837,P07602,Q9Y297,O95772,Q14849,O60749,Q9Y5J7,Q9UKU0,O75208,Q15067,P55327,Q8TCT9,O95831,Q8NBZ7,Q8TCT8,P48637,Q9NZJ7,Q07820,Q9BW92,P22413,P06865,O95684,Q8IYU8,Q9NRG0,P06280 46 +Oxidoreductase activity 0.2879300976664423 0.9972662025069936 0.3186353141850018 1.0 0.4540716797626103 238 P51648,Q8N0U8,P14406,Q9UDW1,Q96CU9,P30519,Q16850,Q9H9P8,O75874,O43676,O75438,O75306,Q6ZRP7,P00403,P13674,P16435,O43169,P09601,Q96JJ7,Q14739,P36551,O15254,P48735,Q15800,Q14534,Q9BU89,P13073,Q15067,Q32P28,Q9BV57,Q99735,Q8NBX0,Q9UHG3,O95831,P61457,Q15392,Q53GQ0,Q6UW02,O15460,O75489,P03886,P00374,O75845,Q3SXM5,Q13423 45 +Peptide transmembrane transporter activity 0.4511545293072857 0.9912414262659788 0.3215677066962792 1.0 0.4575690692919245 3 Q03519,Q03518 2 +Histone acetyltransferase binding 0.5456301455790823 0.9901956131371418 0.3220785163531774 1.0 0.4575690692919245 7 O95905,Q8IXJ6 2 +Heparin binding 0.4512634896259936 0.9874268691978496 0.3234334175995337 1.0 0.458087330232809 15 P10586,O14737,P05067 3 +Threonine type endopeptidase activity 0.5300299926105169 0.984278440277717 0.3249786270691954 1.0 0.458871143816931 8 P20618,P28072,P28074,P49721 4 +Threonine type peptidase activity 0.5300299926105169 0.984278440277717 0.3249786270691954 1.0 0.458871143816931 8 P20618,P28072,P28074,P49721 4 +Phospholipase binding 0.486968695937524 0.9687668738577332 0.3326615179913836 1.0 0.4678157922715709 4 P07196,P20700 2 +Peptidase activator activity 0.4713272695856962 0.9590048656739708 0.337556294004111 1.0 0.4727555233491196 12 P61289,Q9BXK5,Q9UL46,P05067 4 +Glycosaminoglycan binding 0.3972700659757813 0.958368156900084 0.3378771463705523 1.0 0.4727555233491196 21 P15586,P10586,O14737,P05067 4 +Pdz domain binding 0.4373399065033433 0.9543763333534304 0.3398931815713983 1.0 0.475097417946728 16 Q15067,Q15058,P63218,P78536,Q9UQB8,P51790 6 +Low density lipoprotein particle receptor activity 0.4410894020130244 0.933657963969784 0.3504803551514592 1.0 0.4850116978566555 3 Q07954,P98164 2 +Lipase activity 0.419706227548529 0.8961173243097114 0.370190105312312 1.0 0.5082332998748655 17 Q9H6V9,P09601,Q8NHP8,Q8IV08,Q8N2K0 5 +Fatty acid transmembrane transporter activity 0.3959751405741439 0.891585714165517 0.3726150301343414 1.0 0.5101763273665039 2 O14975 1 +Ubiquitin like protein conjugating enzyme binding 0.4584869018454786 0.8821693748369398 0.3776852205592624 1.0 0.5145149113952865 12 Q92564 1 +Complement binding 0.4319123741859095 0.8813993006966574 0.3781017360397638 1.0 0.5145149113952865 3 P35232,Q07021 2 +Opsonin binding 0.4319123741859095 0.8813993006966574 0.3781017360397638 1.0 0.5145149113952865 3 P35232,Q07021 2 +Protein phosphatase activator activity 0.4696547309752509 0.8769672958840017 0.3805044018156089 1.0 0.5152586436293319 4 P0DP25 1 +Phosphatidylinositol 3 kinase binding 0.4682224050984125 0.86940884831416 0.3846235450893598 1.0 0.5193166153541161 4 P0DP25 1 +Mhc protein complex binding 0.4909968105096773 0.7845458219633826 0.4327199059230775 1.0 0.5671531911437503 8 P05026,Q9NUQ9,P50995 3 +Coa hydrolase activity 0.4884878082520392 0.7718536100978132 0.4402011355525341 1.0 0.5731699588620238 8 O14734,P50897 2 +C3hc4 type ring finger domain binding 0.4111900532859742 0.7646339181991056 0.4444895659678762 1.0 0.5782113566667406 3 P0DMV9,P11142 2 +Mrna 3 utr au rich region binding 0.4350408196304766 0.7431205350706191 0.4574087081164615 1.0 0.5905891040610685 12 Q92945,P31483,Q14103,Q13151 4 +Monosaccharide binding 0.3543684529899566 0.7394834844176515 0.4596134648045655 1.0 0.5923337875104336 29 P13674,O60762,Q6PK18,Q32P28,O15460,P35613,P49257,O75503,P52789 9 +Atpase activator activity 0.4264405597701242 0.7320759290676367 0.4641222248577983 1.0 0.5964830075024297 13 O95433 1 +G protein activity 0.4030990430591706 0.7256169682535868 0.4680736159801437 1.0 0.6002824659195616 16 Q15907,P51148,P61020,P20339,Q9H0U4,P51149 6 +Ccr chemokine receptor binding 0.4040852575488465 0.725123911583363 0.4683760162758539 1.0 0.6002824659195616 3 P48681,P42224 2 +Phosphatase regulator activity 0.3632940901003214 0.7139125397610867 0.4752812627922849 1.0 0.6080095785766741 23 Q01105,P35269,O43768,Q86XL3,P0DP25 5 +Ubiquitin specific protease binding 0.4874951167104149 0.7053109651732634 0.4806167381119774 1.0 0.6137038017474008 7 Q9BUN8,Q9GZP9 2 +Flavin adenine dinucleotide binding 0.3546928756922764 0.697910900220193 0.4852329171553391 1.0 0.6190287582827304 27 A1L0T0,Q15067,P16435,O15254,O00116,O95831,Q15392,Q14534 8 +Pre mrna intronic binding 0.4632986561122403 0.6847322936915016 0.4935128668383359 1.0 0.6278605491948765 5 P22626 1 +Myosin v binding 0.4933280733017001 0.6786678188022425 0.4973483610753648 1.0 0.6310050504319986 6 Q15907,P20340,P61026 3 +Aryl hydrocarbon receptor binding 0.3595738384137392 0.6717114226188972 0.5017674280795523 1.0 0.6348707294206186 2 O00170 1 +Single stranded dna endodeoxyribonuclease activity 0.4267100977198604 0.6541670084374189 0.5130042142523608 1.0 0.6473180448929788 4 Q9Y2C4,P49959,P18887 3 +Hormone binding 0.4240406440509791 0.6443409567836746 0.5193543624052701 1.0 0.652053807205295 11 P30536 1 +Translation activator activity 0.4242973964005463 0.6419596107775362 0.5208994077228146 1.0 0.6525346371112515 4 P11940 1 +Calcium dependent phospholipid binding 0.4228657769813315 0.6377426847710175 0.5236411947081465 1.0 0.6533845709607279 11 P20073,Q86YQ8,P50995 3 +Atp dependent protein binding 0.3875074008288907 0.6343276270792486 0.5258670302837694 1.0 0.6549336881842879 3 P08238,Q9UBE0 2 +Nadph binding 0.4527465243431856 0.6339438300550192 0.5261174800615858 1.0 0.6549336881842879 5 P00374 1 +Solute anion antiporter activity 0.4493078745186749 0.617544907152176 0.5368753704851992 1.0 0.6617966378627499 5 P12235,Q02978,P12236 3 +Laminin binding 0.4437203791469086 0.5910731667467624 0.5544713980551472 1.0 0.6780672251106118 5 P08865,P17931,P05556,O94813 4 +Cytokine receptor binding 0.346019307415187 0.5877708498113361 0.5566861126025042 1.0 0.6789809528051634 24 Q9NXR7,P62942,Q9UNH7,Q8WXW3,Q9H2J4,Q3ZCQ8,P78536,Q96J02,Q9NZ08,P14174 10 +Lamin binding 0.4504111911351549 0.5829504155921406 0.5599266801606435 1.0 0.6823338297304418 8 Q14739,P42167 2 +N acyltransferase activity 0.3573662840502035 0.5796914188998353 0.562122731133061 1.0 0.6838092469874572 19 Q96QD8,Q96G23,P27544 3 +Mirna binding 0.3869119657475049 0.5739729461645281 0.5659861087076803 1.0 0.6873042159984779 15 P67809,Q9UGR2,P98175 3 +Poly a binding 0.4014286606489103 0.5490181661918908 0.5829929830718528 1.0 0.7028603557962798 12 O14979,Q07666,P31483,O00571 4 +Intramolecular oxidoreductase activity 0.3387403801291291 0.540395496711586 0.5889243127903376 1.0 0.7071167354264608 25 Q15125,Q6ZRP7,P14174 3 +Class i dna apurinic or apyrimidinic site endonuclease activity 0.3344184670020794 0.5268127820096132 0.5983236057260657 1.0 0.7159251420239475 2 P78549 1 +Rna polymerase ii general transcription initiation factor activity 0.4575200624594571 0.5177867102993993 0.6046070916670041 1.0 0.7215775092294082 6 P13984,P35269,Q15545 3 +Metallocarboxypeptidase activity 0.3973697362089377 0.509005378419855 0.6107484541659103 1.0 0.7268359761071056 4 P36551 1 +Very long chain fatty acid coa ligase activity 0.3962096535386288 0.5034344222331909 0.6146588753906812 1.0 0.7302239731766744 4 Q4G176,O60488,O14975 3 +Dynactin binding 0.4540724328050575 0.5027730541395697 0.6151238405640349 1.0 0.7302239731766744 6 P49841,Q9Y5X3,Q8TD16 3 +Sh3 domain binding 0.3354582622956988 0.4970835322067409 0.6191301469347923 1.0 0.7315131847500883 23 Q96D71,Q9NZQ3,O75525 3 +Metallopeptidase activity 0.3115826624668766 0.4947599493032798 0.6207695786072189 1.0 0.7326770196486564 43 P36551,Q6P179,P22695,P42892,Q92905,Q10713,P55786,O75844,Q9UIQ6 9 +Map kinase activity 0.3594334313163412 0.486582801285782 0.6265540140699368 1.0 0.738248702486479 3 P27361 1 +Long chain fatty acyl coa binding 0.3270198283515914 0.4858182423497382 0.6270960391472165 1.0 0.7382606465957052 2 P22307 1 +Endopeptidase activator activity 0.4159276163723294 0.4632267265130294 0.6432018609037482 1.0 0.7540238031540561 5 Q9UL46 1 +Protein phosphatase regulator activity 0.3327803192148595 0.4621840869778083 0.6439493137762766 1.0 0.7542629936890058 20 Q86XL3,P0DP25,Q01105,O43768 4 +Extracellular matrix binding 0.443851851851855 0.4588649245860622 0.6463311681547346 1.0 0.7564145542991328 6 P08865,P17931,O94813,P05556,P20248 5 +Transcription coactivator binding 0.44066495283885 0.445369675907147 0.6560526227530032 1.0 0.7664991922400408 6 Q71SY5 1 +Long chain acyl coa dehydrogenase activity 0.3802191294047866 0.4282447075918129 0.6684729699658436 1.0 0.777085831082572 4 Q709F0,Q9NZ01,P49748 3 +Steroid dehydrogenase activity 0.4236284953982214 0.4120189383937132 0.6803255421879695 1.0 0.7888614982965679 7 Q53GQ0,Q3SXM5 2 +Sequence specific mrna binding 0.4031420696743786 0.4095695416491408 0.6821217438602678 1.0 0.7894516882300872 9 P00374 1 +Deoxyribonuclease activity 0.3389083598584516 0.4005785886345986 0.6887304122775904 1.0 0.7953149439378948 18 Q8IV08 1 +Protein self association 0.3787079206068546 0.3990122956141206 0.6898841444533323 1.0 0.7953149439378948 11 P53634,Q9BTV4,O43765,Q9Y282,P28288 5 +Translation repressor activity 0.3889477893691685 0.3933309299725321 0.6940750765801607 1.0 0.7988684434819867 10 Q9BPZ3,Q14011 2 +Guanylate kinase activity 0.3997814069385207 0.3925612366226536 0.6946435744140191 1.0 0.7988684434819867 5 Q14168 1 +Abc type transporter activity 0.3863566091556074 0.3807162041173527 0.703413843662867 1.0 0.8039955170093593 10 P08183,Q9HD20 2 +Nadp binding 0.3357762169402529 0.3802151675662995 0.7037857011285098 1.0 0.8039955170093593 18 Q13423,P00374,O75874,P16435 4 +Proline rich region binding 0.4234160782246026 0.3741346441697672 0.7083041449550582 1.0 0.805181124649976 6 P46934 1 +Molecular function activator activity 0.3520736500526465 0.364339324495698 0.7156046381482484 1.0 0.8121498264511601 15 P31749,O95433,Q96KC8,O60884,P05026 5 +Oligopeptide binding 0.3915056105199398 0.3575898291869296 0.7206502908261352 1.0 0.8165409009523883 5 Q99735 1 +Carbon sulfur lyase activity 0.4098362256156268 0.3536416163672953 0.7236074818360707 1.0 0.8185551628267858 7 Q99735 1 +Mrna 3 utr binding 0.2868055905952538 0.3510469308339343 0.7255531403466493 1.0 0.820087751466734 51 Q14011,P22626,Q9Y6M1,P31483,Q92804,P35637,Q14103,Q13151,Q01085,Q92945,P07910 11 +Beta tubulin binding 0.3343191059020187 0.329865175312795 0.7415018381007863 1.0 0.8328603329317235 17 P50402,O14737 2 +Oxidoreductase activity acting on the ch nh2 group of donors 0.3259325044404977 0.3247727472458181 0.745353071941685 1.0 0.8349879450000475 3 Q9NVS9,P00367 2 +2 oxoglutarate dependent dioxygenase activity 0.3200214739329117 0.3226547698535838 0.7469567098713157 1.0 0.8361096075011178 19 P13674,Q9NVH6,Q32P28,O15460,Q8IVL6 5 +Notch binding 0.3232682060390755 0.3127791072596567 0.7544484895304968 1.0 0.8430260910869606 3 Q13573,P78536 2 +Nucleotidase activity 0.3990292344614449 0.3095875530472042 0.7568746228018903 1.0 0.8444871193320127 7 Q9H0P0,Q969T7,Q9NX62 3 +Channel inhibitor activity 0.3879109246826703 0.2990742079415339 0.7648834252169876 1.0 0.8520531253621018 8 O43768,P46934,Q9NWR8 3 +Regulatory rna binding 0.319567418495266 0.2779604313628129 0.7810427334205889 1.0 0.8666887285645422 18 P67809,Q9UGR2,P98175 3 +Carboxy lyase activity 0.3461897113706869 0.2776877071354976 0.7812520979025792 1.0 0.8666887285645422 13 P38435,Q8NBZ7 2 +Cxcr chemokine receptor binding 0.2838117786327402 0.2676331826813646 0.7889816863236363 1.0 0.8725948849539499 2 Q96J02 1 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.2969678926316922 0.2412462081449218 0.8093642993499595 1.0 0.8893525418249179 28 O95298,Q9Y6M9,P56556,O75489,O43674,P03886,O95168,P51970,O75438,O43676,O75306 11 +Atp dependent peptidase activity 0.3879880049174826 0.2393454507017637 0.8108377247935132 1.0 0.8893525418249179 6 Q16740,Q9Y4W6 2 +Insulin like growth factor binding 0.3055062166962692 0.2367758769035421 0.8128306669070009 1.0 0.8904569579060121 3 P98164,P20248 2 +Channel regulator activity 0.2997436204274331 0.2350744497896138 0.814150949196979 1.0 0.8911999349253996 20 P31749,O15400,Q9NWR8,P46934,O43768 5 +Carbon carbon lyase activity 0.306013472551715 0.2333332566105902 0.8155026361657283 1.0 0.891273747242544 19 P38435,O95470,Q8NBZ7 3 +Transmembrane transporter binding 0.2840055831622879 0.2271634759536072 0.8202966272566341 1.0 0.8951035523838115 35 P0DP25,P30536,P21796,Q96PU5 4 +Mhc class ii protein complex binding 0.3771557463836523 0.2256670058191149 0.8214604216775567 1.0 0.8952625589383517 7 P05026,P50995 2 +Signaling receptor binding 0.2524877894374487 0.2197912492768922 0.8260337350681008 1.0 0.8985382635380281 191 Q99584,O15258,Q96D09,P01889,P46934,Q15375,Q9H2J4,P06576,O43768,P43490,Q13445,P51572,Q92520,P05067,Q9BUN8,Q9BQE5,Q9NUQ9,O60749,Q9NZ08,P14174,P0DP25,P04062,Q9UMX5,P10909,Q92896,Q8WXW3,Q3ZCQ8,Q9Y5X3,P08236,P46379,Q92542,Q13501,P20073,P22413,O75381,P06280 36 +Cytidylyltransferase activity 0.3550421025844159 0.2158112458011246 0.8291348819951581 1.0 0.9000495608356345 5 O95674 1 +Scaffold protein binding 0.3031175488234425 0.2155116431892417 0.8293684353809629 1.0 0.9000495608356345 19 P08670,P07602,Q9UQB8,Q9NZJ7 4 +Phospholipid transporter activity 0.3573333498752545 0.2095018232582238 0.834056512212439 1.0 0.9021669414296528 9 Q4KMQ2,Q7Z3C6,P08183 3 +Phosphatidylinositol phosphate binding 0.281369360151629 0.2046892156142089 0.8378149467095941 1.0 0.9044402496974452 35 Q9H4A5,P31749,Q9H4A6,Q9BWH2,Q9Y5X3,Q96L92 6 +Poly purine tract binding 0.3225721717584751 0.2030423146810619 0.8391019586592294 1.0 0.9044402496974452 15 P11940,P31483,Q96EP5,Q13310,O00571,O14979,Q07666 7 +C acyltransferase activity 0.3353584610063275 0.1919345194557496 0.8477934974866932 1.0 0.9115124837694136 11 Q9BWD1 1 +Glutamate receptor binding 0.365256691529737 0.1833446600713547 0.8545275945836899 1.0 0.9180219050171528 7 P0DP25 1 +Pre mrna 3 splice site binding 0.2633915359573929 0.1810298739653607 0.8563441273666257 1.0 0.9192619093463856 2 P26368 1 +Retromer complex binding 0.3055966834468401 0.1329108783138828 0.8942638635860032 1.0 0.9533319836078128 4 Q99523,O60493,P51149 3 +Phosphatidylinositol binding 0.2546139649752009 0.1173896668461138 0.9065512721199318 1.0 0.9632431154575052 62 Q9H4A5,P31749,Q9BWH2,O43292,Q9Y5X3,Q96L92,Q8WTV0,O60749 8 +Calcium dependent protein binding 0.27744947201838 0.092679758602109 0.9261579780832369 1.0 0.9798073731551316 22 O75131,O75340,Q99584,O76024,P50995,P20073,Q99816,Q9H9H4,P60903,P0DP25 10 +Poly pyrimidine tract binding 0.3024098165158433 0.0779058855609349 0.9379029176423416 1.0 0.9878697125435169 13 P11940,Q96EP5,P26368,Q13310,P31943,Q07666,P07910 7 +Nadp retinol dehydrogenase activity 0.3353800272744361 0.07689662938677 0.9387057789691372 1.0 0.9878697125435169 6 Q9Y394 1 +Phosphatase inhibitor activity 0.3260269217898321 0.0768273214495769 0.9387609155943072 1.0 0.9878697125435169 8 Q01105 1 +Mdm2 mdm4 family protein binding 0.3339259259259296 0.0731612300864934 0.9416778175840356 1.0 0.9901884930353344 6 P61927,Q96JB5,P61289,P04637,P62841 5 +Kinesin binding 0.2958495653152656 0.0625956070780887 0.9500885276032132 1.0 0.9967671022775962 14 Q9H0B6 1 +Gdp binding 0.2702830439332198 0.0492903187041092 0.9606879346962548 1.0 1.0 28 Q15907,P61020,Q15382,P20339,P51151,P61019 6 +Gamma catenin binding 0.3213656239790225 0.0427161502720871 0.9659278052649836 1.0 1.0 6 Q14574 1 +Hsp70 protein binding 0.2794529939582488 0.0205460829240417 0.9836077509662088 1.0 1.0 16 P46379,O60884,O75937,Q07812,Q96EY1,Q99543,P06493,P37198,Q9UNE7 9 +Phosphatase binding 0.2575909707476688 0.0200038868274835 0.9840402719468628 1.0 1.0 47 O43815,P78318,P53634,P35222,P49815,P46940,P18031,P30260,P00533,P41240,P62258,Q9UJX3,P35269,O43768,Q86XL3,P27361,Q9NX63 17 +Chemokine receptor binding 0.284063981042651 0.015304565306818 0.9877892003224482 1.0 1.0 5 P48681,P42224,O43776,Q96J02 4 +Nuclear export signal receptor activity 0.3011888533104488 0.0108900879497747 0.9913111387005876 1.0 1.0 8 Q9C0E2,O15504 2 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..236445bb723fd6abb8f72b48512d80299abbca91 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "3 phosphoadenosine 5 phosphosulfate binding", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Camp response element binding", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel activator activity", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromatin insulator sequence binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidine deaminase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Demethylase activity", "Deoxycytidine deaminase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Fatz binding", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Icosanoid binding", "Identical protein binding", "Ige binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreductase activity acting on the ch nh2 group of donors oxygen as acceptor", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidic acid transfer activity", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphatidylserine flippase activity", "Phosphatidylserine floppase activity", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphorylation dependent protein binding", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Platelet derived growth factor receptor binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoic acid responsive element binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Superoxide generating nadph oxidase activator activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane receptor protein tyrosine kinase adaptor activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor activated receptor activity", "Vascular endothelial growth factor binding", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Wnt protein binding", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding"], "available_proteins": ["AACS", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL8B", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRIX1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1D", "C1QBP", "C1orf123", "C1orf35", "C2CD2L", "C2CD5", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA5", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDR2L", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP135", "CEP250", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAHD2A", "FAM120A", "FAM129B", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNBP1L", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCN1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GIGYF2", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLPH3", "GOLPH3L", "GOPC", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR89B", "GPRASP2", "GPS1", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN3", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNOP1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRRFIP2", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LZIC", "LZTFL1", "MACF1", "MAD2L1", "MAGED1", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METAP1", "METTL13", "METTL15", "MFAP1", "MFF", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCK1", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NKRF", "NKTR", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDSS2", "PDXK", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGK", "PIGL", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REL", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RILPL1", "RIOX1", "RIOX2", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIKE1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNE2", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", 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remyelination 3 5 2.889179112907827 0.0038624899746066 1.6601941747572817 4.737864077669903 1.1231406516527276 0.2457358043386077 1.1021021225411718 1.375663406058269 1.1869683790120098 0.2709829643602553 0.0003591188143491 0.0014481500629001 0.0057815105752346 0.0025975272437437 0.0020033682110678 +Weakness due to upper motor neuron dysfunction 34 140 2.874570497401346 0.0040457743930166 28.555825242718445 137.6601941747573 0.2819022815105153 0.6881655137318178 9.386485329623984 15.002137969356786 0.8452864981616559 0.3517395097735512 0.0008319206349433 0.0294452257065595 0.008595429078692 0.0012540735775596 8.13285973397768e-05 +Abnormal tissue metabolite concentration 9 16 2.8703586811053388 0.0041000642197555 5.895631067961165 14.650485436893204 0.4799987914691458 0.2340469593783387 2.3926019349714145 2.328417679576543 1.7567023743300048 0.2768423789344761 0.0004460099789783 1.0 0.0405463165390607 0.0078094686864188 1.919664749495764e-05 +Horizontal nystagmus 7 24 2.856683802432234 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0.0203848430395501 0.0005673930602398 0.0001266725713312 +Abnormal visual electrophysiology 15 48 2.738245451094479 0.0061767956533849 11.310679611650484 49.08009708737864 0.5738496712827478 0.4298926605512212 5.601714588788375 4.822166856762376 1.2686017151039417 0.3684491475281102 0.1561494015269899 0.1520007577137938 0.0129822264373555 0.0596487583268479 0.0230654966497714 +Abnormal delivery 7 24 2.7253706232608272 0.0064229343194754 5.699029126213592 21.5873786407767 0.8953606264352741 0.420193574632847 2.851791981194637 2.0047603353673553 0.8292150006712276 0.3226752218541708 0.0198174339809626 1.0 0.0132042256106822 0.0341229578056568 0.0029760556157756 +Bilateral sensorineural hearing impairment 8 25 2.7215188552302942 0.0064982677906961 6.381067961165049 24.424757281553397 0.7447297270654177 0.4543730451773109 2.694462286764978 2.8252792093863337 0.8997615483176746 0.3241521581359238 0.0247767934162638 0.2295798469686227 0.0965403494275516 0.0094868932073139 0.0010655904765625 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20.660194174757283 86.74029126213593 0.5649049994066069 0.3835571498509289 6.419862077062851 7.868335701486235 1.546158503499524 0.3590721878602594 0.0052049803899395 0.0990971562045587 0.0017909221198074 0.010203975961045 5.5375062590002846e-05 +Bulbar signs 7 12 2.671151397611674 0.0075591543973159 4.888349514563107 12.016990291262136 1.527818207801298 0.1656113111527082 2.218011046873564 1.4803576942139227 1.2783367300196684 0.2344360472575242 0.0027269610371842 0.1430638950507344 0.0035907130786718 0.0009276346440678 0.0001106790733064 +Central scotoma 8 11 2.6657965646716466 0.0076806154978781 3.657766990291262 9.152912621359222 1.2790732929494344 0.2261272578521709 2.0233738200365714 2.077016218281829 1.2675536526802949 0.279373459017325 0.0001392709260391 0.1221118561195742 0.2318581098993339 0.0004102788019959 2.8968816708506228e-05 +Abnormal chorioretinal morphology 12 30 2.664735316483468 0.0077048939374759 8.45631067961165 26.4004854368932 0.7945769566543296 0.4616483000942599 3.6317817687878136 4.493501214243663 0.9878512993647718 0.3399479614013815 0.0574521303340664 1.0 0.6667362314719443 0.5099520664807343 0.0458044806843984 +Barrel shaped chest 3 5 2.664432542011269 0.0077118331834882 1.674757281553398 4.473300970873787 1.1869997902874323 0.2609030887925388 1.0385967424919742 0.917344085691108 0.8975397916941404 0.2534223349008651 0.0674209136026369 1.0 1.0 0.0435926191526008 0.0037486095651754 +High frequency sensorineural hearing impairment 2 5 2.659399453442233 0.0078280091257558 1.6650485436893203 4.043689320388349 0.9386965591020852 0.2149168047575724 0.8809977505524413 0.5895810431067134 1.3383980938857114 0.231944191038228 0.0002762961331744 0.0238038053541035 0.0009157120850054 0.0001338651392195 0.0010631590368518 +Loss of speech 7 20 2.6470227407806504 0.0081203892077823 5.453883495145631 19.1626213592233 0.4726173662677797 0.3013153148889984 2.223071754411353 1.8941045281154043 1.521023928928509 0.3006842241053739 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2.429189656910488 0.0151326140521497 5.912621359223301 18.439320388349515 1.0629964764413025 0.2985925736346436 2.390745896997379 2.2281751696560335 1.2165016471530676 0.297036724651636 0.0040775097697983 1.0 0.0046396659223567 0.0096252938706505 0.000217728528826 +Corneal opacity 19 59 2.42843841399668 0.0151640002741375 15.480582524271844 53.95631067961165 0.9517965339960472 0.3644495779961974 5.277458167452316 6.791845051563607 1.5225460520633525 0.3686110256368129 0.01395511898958 0.6010849010057636 0.1116667861353323 0.0871297850488539 0.0008695992488445 +Arthritis 12 43 2.4278698477676777 0.0151877925331418 10.45631067961165 41.12864077669903 0.9299077951686036 0.3844403642845474 3.7326340917241647 4.351147052994631 1.200139433310656 0.3557501916131977 0.0489480835065662 0.0948632313276182 0.0039499040991049 0.1198850598560501 0.0021820294106423 +Abnormality of fontanelles 15 54 2.4221704994341904 0.0154281100297821 12.533980582524272 46.23543689320388 0.679338498231045 0.5021510160434427 4.713779704909753 4.753170281164529 0.9735403185104452 0.3677424081230729 0.0123123303140188 0.4436569660453457 0.001125421248196 0.0270561912398673 0.0058713612820935 +Cherry red spot of the macula 6 10 2.4088441356846646 0.0160031308275168 4.87621359223301 9.031553398058252 0.4125318500531191 0.1346012745180574 1.6566187440434876 0.4477283705000042 2.101542046986786 0.2228325403979826 1.778722199929925e-05 0.0561990347849709 0.0057815105752346 5.41373461507268e-06 3.957975029002194e-07 +Abnormal social behavior 24 76 2.408201300954093 0.0160313388253892 16.796116504854368 65.80339805825243 0.6678301735588785 0.4940185804874849 5.994105880514205 6.839540104535511 1.1033956384068455 0.3774724921329495 0.0124966582822351 0.1861284851480595 0.2132739791887914 0.0178380374686823 0.0025804138601819 +Neurofibrillary tangles 3 5 2.402087223822244 0.0163018208805172 1.9878345498783456 4.347931873479319 0.5966090900062281 0.2642083372508564 1.0995898071170882 1.1496807364853057 1.4348037417662018 0.2714513638042118 0.0006915935551566 1.0 1.0 0.0435926191526008 0.0037486095651754 +Corpus callosum atrophy 4 16 2.3996422252380274 0.0164111031260603 3.8907766990291264 14.728155339805824 0.1983845931768132 0.4648037373286657 2.580775148596329 1.1570314775092398 1.0666401582531118 0.3051438618178521 0.0223651585611987 0.0919337377678228 0.0008978593047678 0.0116756742779249 0.002252196025852 +Motor neuron atrophy 9 24 2.385843056975203 0.0170400212389205 5.410194174757281 22.424757281553397 0.8356342611289532 0.3959768073616548 2.754377444710008 1.6813276911909307 0.954775311801755 0.3176984078794489 0.0672727797859516 0.2145132052152406 0.3867843928732056 0.03203241935523 0.0005965799784821 +Joint swelling 1 6 2.3774356729072914 0.0174334834497529 1.6650485436893203 6.740291262135922 0.3109744271340265 0.4064008040369078 1.2500259211187394 1.1979059044612257 1.115547263835383 0.290400539923086 0.1249795934205531 0.0919337377678228 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0.0187213719816943 6.070388349514563 21.26456310679612 0.7442674094202993 0.3924071478475022 2.7239314899251803 2.029014432281319 1.0984628042075235 0.3129154853478004 0.044158568500743 0.2624522374738631 0.460215575147234 0.1942870876140905 0.0032211385990827 +Abnormality of the spleen 28 120 2.35043016248106 0.0187517261685357 25.813106796116504 118.70145631067962 0.3588217969137363 0.458825127767632 7.787937091054707 11.816587724549532 1.4144879662363967 0.3705037351683085 0.0416877274863009 0.2350253809266401 0.0199961820074726 0.0433014656111718 0.0033500787281882 +Difficulty walking 22 80 2.348238024827776 0.0188624630172731 15.580097087378642 75.13106796116504 0.4697839455005359 0.5877808014506588 5.810176207602449 9.191717769736409 0.8615188656802858 0.3499503569147802 0.0023213565475571 0.0814002886995259 0.0552350502434807 0.0052893376956772 0.000638281439709 +Peripheral demyelination 6 16 2.3474370776934417 0.0189030656589215 4.524271844660194 16.973300970873787 0.9472740181618832 0.3208012027704231 2.3341893675900383 2.269845761985369 1.1784704386991718 0.3026863353342601 0.0058488315814163 0.0142466262053111 0.0058560324261939 0.0128293519549119 0.0020949039384023 +Osteoarthritis 6 12 2.346735890125581 0.0189386738850194 3.783980582524272 10.466019417475728 1.011181157871384 0.2141266987491498 1.7388858389175554 1.4384831140913243 1.3548711699904423 0.2434324139099127 0.0100782524716357 0.1263420182810564 0.0024390672757694 0.0291459656321865 0.0019380906235741 +Visual field defect 17 49 2.346359447262276 0.0189578148723903 10.441747572815531 43.536407766990294 0.5300405726422278 0.5592030820157294 4.192457959491754 4.4874295525463 0.9433269391526378 0.3481975369092003 0.0266760684403374 0.1420347049671142 0.1503379894830936 0.0495284562350144 0.0010656958740985 +Mucosal telangiectasiae 4 10 2.344363966238455 0.019059561842013 3.2354368932038833 9.689320388349516 0.8501086222195428 0.291727970426265 1.410916714116348 1.5996305775803197 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2.317049983898417 0.0205010091128055 39.97330097087379 184.7135922330097 0.2254846155090266 0.7235761385556879 12.871537267469767 19.604722774296683 0.8047704019364031 0.3342405671672314 0.001595876511909 0.0770489496829474 0.0413149518349569 0.0393904089917717 0.0001231547614104 +Respiratory failure 20 72 2.3137644173340663 0.0206806481956651 15.308252427184469 64.92233009708738 0.6334303745407566 0.5052857133990365 5.520010364276267 5.289556151454055 0.9962199001839442 0.3695677120431103 0.0035058465086002 0.1757629685498992 0.0675797720929864 0.0143012913315375 7.912405289028931e-05 +Abnormal larynx physiology 6 16 2.3062976079508952 0.0210940087164028 3.7694174757281553 14.78640776699029 0.7777362681295714 0.3936810823701626 2.010346212391085 1.51625807571557 0.9784109402665334 0.3028779878197117 0.0239443294188339 0.1594721229818057 0.2966243410810411 0.0106277501006418 0.0072126726017668 +Premature rupture of membranes 1 6 2.298140186126173 0.0215538116950726 1.5631067961165048 5.800970873786408 0.9509293139272904 0.2937126614282376 1.1899245542912666 0.3992700002908385 1.068670600999266 0.275907562675117 0.0294966217370324 1.0 0.0032139762811053 0.0186627473263165 0.0677640175569944 +Abnormal pulmonary interstitial morphology 5 28 2.2960226036879336 0.021674588992981 6.371359223300971 30.5995145631068 0.4103689768813533 0.4555813960836699 3.330566746297264 2.186076806332745 1.1224431747517174 0.329794447909787 0.0384219696521857 0.0068431745235502 0.0001297463919402 0.0133560961650828 0.0984900841438662 +Undetectable electroretinogram 2 5 2.295112265048272 0.0217266913680107 1.7427184466019416 4.415048543689321 1.0664751707047182 0.1916317897201908 0.9612998826677368 0.7632752290710167 1.383034454070232 0.2429274936147374 0.0589581135287866 0.0607401038440192 0.0067896670197663 0.0379575415698398 0.0227185425065092 +Abnormal exteroceptive sensation 14 52 2.293210685835904 0.0218358782400109 10.759708737864075 52.02427184466019 0.4941713240335635 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54.21116504854369 0.2005252410651455 0.6758492800321638 4.7575261230971835 6.937765763435153 0.737701572424903 0.3115763272161692 0.0778654602194462 0.6574721749282701 0.6340998392238457 0.1628263896511071 0.1845951183594405 +Hypocholesterolemia 3 8 2.252934465890653 0.0242632813277858 3.2645631067961167 8.048543689320388 1.205673434171466 0.2055905154190861 1.747510449264718 1.0646904903887575 1.232151298114248 0.2464368010987078 0.0589581135287866 1.0 0.1191939669275513 0.0379575415698398 0.0027834726260547 +Ankylosis 3 6 2.2524272722364587 0.0242952838920775 1.7160194174757282 5.099514563106796 0.776290643053947 0.3289690792318075 1.1013829257517682 0.4264322039260138 1.078831323421012 0.282224813150681 0.3548108655020613 1.0 0.1277572387780678 0.2897526236095206 0.0278921605814954 +Arthralgia 9 35 2.2481460218926164 0.0245668802908427 8.067961165048544 33.66019417475728 0.4973169065736986 0.5336317295986659 3.339269543758109 3.852381429809718 0.8994568503620952 0.3283969638661596 0.189610057612467 0.3807425591661329 0.2498296739424394 0.4290147172235293 0.0218930489067315 +3 methylglutaconic aciduria 7 13 2.244367288294641 0.0248087794107938 4.072815533980583 10.594660194174756 0.3579974396117663 0.4371570089867337 2.2174372584356252 1.5620718849823747 1.1566220028171512 0.333066618505644 0.0019179537012613 1.0 0.1611939416425752 0.0688460117016781 8.4232111792365e-07 +Abnormality of the 5th toe 6 11 2.239284940664186 0.0251373820976212 2.9223300970873787 8.259708737864077 1.1073405288994291 0.2882520454965396 1.560677724258624 2.165041741031587 0.9522253135241228 0.2721172964763348 0.8378841415268777 1.0 1.0 0.7584198129875613 0.5410497954439945 +Postaxial foot polydactyly 6 11 2.239284940664186 0.0251373820976212 2.9101941747572817 8.179611650485437 1.1164564935210708 0.2854713626620553 1.5514456024758956 2.174827712105029 0.9565986562813577 0.2724819159224514 0.7708929437280028 1.0 1.0 0.6835238209809511 0.4023686447738411 +Abnormal bone structure 46 184 2.237130025871837 0.0252778430479183 37.41747572815534 174.03398058252426 0.5052466892255619 0.6451089511590872 11.181012226303604 17.857684720378465 0.8786021869184294 0.373142151762858 0.0243250874437418 0.4442196805921763 0.025332220693489 0.0383193781882679 0.0009306673029678 +Muscle abnormality related to mitochondrial dysfunction 10 38 2.2366000115944487 0.025312494169114 11.12378640776699 35.58252427184466 0.9791864828781052 0.3365990386989574 4.6259837298613 4.333263242301439 1.4740065920951253 0.3430734831138388 0.0008981750032669 1.4912245191089107e-05 0.0004360874746147 0.0010122977413289 0.0003049753977574 +Thickened skin 24 106 2.236384005355894 0.0253266279493369 22.009708737864077 100.32766990291262 0.4385550996860712 0.6098739890089617 6.832596267878453 10.09935648280444 0.8592900670649001 0.3543867989618216 0.0204899737956151 0.3756902934555408 0.0481067760820328 0.120399639263492 0.0015661852336767 +Thoracic kyphosis 4 17 2.231952061701768 0.0256181314538297 3.849514563106796 15.725728155339803 0.7266071624304212 0.4267138621860136 1.957478752201897 1.77496566461622 0.8648337345468261 0.3040731381323691 0.0046181094332973 1.0 0.0474859144951228 0.0016056440309417 0.0072126726017668 +Tissue ischemia 7 21 2.229580623529752 0.025775297397804 4.669902912621359 20.01941747572815 0.4670703905456849 0.5376214087969519 2.554791232762714 1.8952192409705757 0.8387891641382008 0.309595447618788 0.3913987265429908 1.0 0.5107150602013826 0.5291696351238756 0.0248860158637803 +Pericarditis 3 5 2.228797654728895 0.0258273710700198 1.5412621359223302 4.808252427184466 1.0465356013883245 0.3273693330411259 1.0523881114446327 0.8152847226576512 0.8192491618381674 0.278983410545408 0.3548108655020613 1.0 0.1277572387780678 0.2897526236095206 0.0037486095651754 +Abnormal morphology of the conjunctival vasculature 2 6 2.2257658096523523 0.0260298720764182 2.6359223300970873 7.330097087378641 0.3791669082255805 0.3264494094231241 1.4642904354684148 1.4524057679745994 1.3542312898692437 0.2989163062985944 0.0194443138265815 1.0 1.0 0.0757571260003459 0.0621142898948071 +Muscle weakness 68 301 2.224660210369957 0.026104057314493 62.08495145631068 284.65776699029124 0.4543336947629458 0.7075817001495509 18.861530859314332 26.81339440066312 0.9176952901579704 0.374241019778978 0.0002459681459639 0.1200699867731065 0.1455404598381822 0.0112848735674878 3.217347351349706e-07 +Functional abnormality of the inner ear 53 259 2.2209046140556605 0.0263574226584268 50.34708737864078 242.22087378640776 0.1935297291549575 0.7944300178060495 15.81548387978023 20.65122416300477 0.6774851275041758 0.3153094731961924 0.0008694912003467 0.0901161496803885 0.0100194856400934 0.0040335590830115 7.069420594024036e-05 +Widely patent fontanelles and sutures 1 5 2.219876519244978 0.0264271508255997 1.1820388349514563 4.492718446601942 0.9268776256964488 0.3164973394666702 1.0535965765247446 0.6700567925136669 0.9657871794386532 0.2673092477645348 0.0361319669005298 1.0 0.0039921150854813 0.0229613270793894 0.0820486275159116 +Abnormality of glycolipid metabolism 5 7 2.216860516038083 0.0266326246161514 3.83495145631068 7.228155339805825 0.3163887308740252 0.1681411938672545 1.311614193945771 0.5964160722258837 1.870431483654663 0.2292796295173983 0.0001599969352142 1.0 0.0930016660897952 0.0014684283121974 2.285385949037992e-06 +Areflexia of lower limbs 6 21 2.2162183076947097 0.0266765546402192 6.601941747572815 21.186893203883496 0.8014885285213843 0.4297204254543569 3.042066893889402 3.372723692373783 0.977277602505203 0.3249512351298445 0.0130879818364426 0.1991580424676108 0.3622612502953293 0.0989248704147511 0.0063580922287898 +Supranuclear gaze palsy 7 20 2.209181208589098 0.0271620393928806 5.186893203883495 19.1626213592233 0.8242716574954257 0.3183493558985887 2.2612229396433574 2.139608194404574 1.2188387108542005 0.2935859783151378 0.0065434984200872 1.0 0.0548237001435711 0.0671599559498881 0.000479523089417 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2.189963221243606 0.0285269042616465 6.691747572815534 26.449029126213592 0.5692557086068671 0.4287880468715059 3.1782986616871702 3.4415823902191023 1.075640445131052 0.3251004953320756 0.1843136125706765 0.080392228927645 0.0150746255639145 0.2115848051300181 0.1994436791371063 +Abnormality of the wrist 11 35 2.186915109478917 0.0287487217032316 6.95873786407767 30.155339805825243 0.4893391061224179 0.4739542714047036 3.2628753712893035 4.83666675230799 1.0000289125440789 0.3174741185520122 0.0755108954178026 0.0775893010402436 0.0140670545597734 0.0822680536417182 0.0023152575232889 +Abnormal sensory nerve conduction velocity 1 5 2.1840881317350584 0.0289557726169447 1.7985436893203883 5.902912621359223 0.8037131919369849 0.3936255661985234 1.335002205566696 1.3883325411414074 0.8826639189987078 0.3019282509850424 0.0949181274262904 0.0786913117950012 0.152955667850895 0.3400030327298383 0.1992011927715255 +Anterior rib cupping 1 5 2.183506509929512 0.0289985300797674 1.0995145631067962 4.240291262135922 0.7580083586017852 0.4401791439408411 1.122280859436629 0.8606995983858212 0.9577037409012152 0.3293084857529619 0.0234121875355895 0.0378187125466048 0.0025156479029566 0.0147480216610697 0.0544194668097373 +Endocarditis 2 5 2.1834846803327914 0.0290001359227431 1.6699029126213591 5.055825242718447 1.0315066990472646 0.3137673633075574 1.128951309195931 0.7031759081548564 0.9300019606367588 0.2935479974969262 0.3131041734647267 1.0 0.1105474823156849 0.2541534411772372 0.0181181417645757 +Severe muscular hypotonia 9 33 2.179503579881902 0.0292942790172923 7.621359223300971 29.08252427184466 0.4891205928109223 0.6102633656375805 3.107668263506767 4.151030453059386 0.6943996582599059 0.3174497499656805 0.0231518438894677 1.0 0.2246728541934789 0.3835116962454471 0.013664886761375 +Underdeveloped supraorbital ridges 5 14 2.17724318915434 0.029462427448619 4.665048543689321 12.08980582524272 0.8524762858030893 0.4193185978455835 2.3718498265247017 1.7978393075824093 0.8920190977636392 0.3291411492922084 0.1679315882748155 1.0 0.0733374275738533 0.3051232152156647 0.0230912453221162 +Abnormality of the achilles tendon 10 14 2.176379370890841 0.0295269050238606 4.514563106796117 12.898058252427184 0.5609866518495084 0.4955323823848279 2.2986449265697204 1.5070372517492898 0.9168070129914432 0.3209091792598189 0.0197718902859207 1.0 1.0 0.1975866021584996 0.0054053690368969 +Coxa vara 6 16 2.174981279216809 0.0296315192982539 4.310679611650485 13.54126213592233 0.853738655548226 0.4218003203060939 1.9720332330132235 1.9928869528934432 0.8140335419312188 0.3116542205645756 0.0081025339600962 1.0 0.0599227725053796 0.0756846958642696 0.0032909138457879 +Deformed sella turcica 1 5 2.1749248780300823 0.0296357462808332 1.449029126213592 4.361650485436893 0.6519584745232953 0.4108786670869809 1.0702617541763486 1.191712968868623 0.98030484078304 0.3007326817007539 0.3131041734647267 1.0 1.0 0.2541534411772372 0.1129571724371578 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1.9466019417475728 5.980582524271845 0.6333430474464145 0.2773316461993735 1.2136213588737947 1.4646685732948297 1.3006352977804805 0.2635985168358294 0.1461066830947072 0.1006582454154426 0.0190005699483642 0.097689242801984 0.0888008652079453 +Congenital ichthyosiform erythroderma 1 6 2.1614786664481347 0.0306583831584865 1.483009708737864 5.451456310679611 0.3763011420656366 0.4420094691835529 1.3209303392195928 0.7727600360616235 1.004780932779387 0.2961698816845319 0.050899384243609 0.0561990347849709 0.0057815105752346 0.032628233248221 0.1129571724371578 +Frequent falls 7 41 2.154563294027584 0.0311960240010513 8.643203883495145 38.75485436893204 0.6268988624161936 0.4831027569691007 4.0086529499315136 3.828305504664436 1.0909180744790496 0.3651237988976172 0.0165713984509496 0.0080720369936571 0.0014587990578306 0.0175312180624397 0.0235212982094472 +Progressive visual loss 7 25 2.154534440636035 0.0311982840710387 5.325242718446602 22.429611650485437 0.7316954387450431 0.34231947196034 2.467466703195611 2.985791083259841 1.255625436621734 0.3056268024259221 0.0774724656304003 0.0490886173861251 0.0057249284475035 0.0328918504861857 0.0267628454277298 +Deep plantar creases 1 5 2.152328809522228 0.031371466314255 1.8349514563106797 5.186893203883495 0.878985239421048 0.4043272377350911 1.2929764516183682 0.5365505235508999 0.7767472061372565 0.306948917766608 0.3939928003913119 1.0 0.144637307685789 0.3236592382947187 0.1812716861639223 +Cerebral white matter atrophy 10 22 2.149959929841763 0.0315583844715634 5.131067961165049 20.973300970873787 0.1808693579834183 0.5584858449574669 3.2196764333061645 2.226662306215603 0.8925813851884131 0.3132328134404136 0.0919555001437701 0.1553991536419083 0.0046396659223567 0.051542815486873 0.0259406914165302 +Neuronal loss in central nervous system 4 11 2.142532145210725 0.0321506848124477 4.087378640776699 12.526699029126211 0.982175765643533 0.2959736314179056 1.731247914675439 1.993135251988059 1.1236470294677874 0.2967990988512021 0.0128570302175003 1.0 0.03403446937649 0.0348798008289802 0.0138780941766985 +Pathologic fracture 5 15 2.13993285629069 0.0323601933602963 4.257281553398058 15.072815533980584 0.983166532607372 0.3143076297274698 2.133145812327421 2.2800397788540345 1.0713003315034937 0.2893419439464214 0.1176423974690522 0.1715759324473242 0.0548237001435711 0.2421879711614701 0.0393164024746651 +Morphological abnormality of the corticospinal tract 4 15 2.137706914039166 0.0325405380068977 3.686893203883495 15.03883495145631 0.5616218245613079 0.5231151147988415 1.9487419537195845 1.7976377708768945 0.8440336488225383 0.3280840546625515 0.1755702870596285 0.2030241760545403 0.3684815592825167 0.1038817567329197 0.0767262889545654 +Lower limb pain 0 5 2.135583565408528 0.0327133721702053 1.5825242718446602 4.990291262135922 0.5428874178676697 0.3877045147354496 1.3258027196203157 1.119076818129616 1.1147585770582464 0.3126977330206063 0.4308023581825691 0.083126337411673 0.1611939416425752 0.3559534457378639 0.5927878722461318 +Abnormal speech prosody 2 8 2.1339824103556806 0.0328442206983479 1.7184466019417477 7.531553398058253 0.8238611105871386 0.3292070194756458 1.3593793253030109 1.1305443806694235 1.0768574157850217 0.2870822069632543 0.0142767807743484 0.0786913117950012 0.0115435449528709 0.0073447144383531 0.0468003866103798 +Lower limb spasticity 18 80 2.1337011742902963 0.0328672498912732 17.24271844660194 80.34466019417475 0.5234592060757025 0.5553383930423336 6.384471482056576 8.884788223572686 0.9712236167697867 0.3629508150226985 0.0016390356360378 0.5911762082883738 0.0332641738139971 0.0049863628675692 0.0015511797327419 +Abnormal neuron morphology 10 29 2.130447135556707 0.0331347158501675 6.186893203883495 28.24514563106796 0.6484714329574719 0.4735595458743487 3.2896606279139218 2.2567268866496706 0.9337112301481814 0.3347227917865519 0.1569508810587452 0.2801168002074996 0.4860789703868964 0.0814773755217055 0.0054148182776431 +Constriction of peripheral visual field 7 22 2.130110666354848 0.0331624779336459 5.286407766990291 20.194174757281555 0.2138296180164327 0.5608156359645686 2.8702541595688347 2.312096734409207 0.9154059705709106 0.3137235798233571 0.0230436364337774 0.225839943305071 0.0935352604171004 0.0385372375494843 0.0038055285280442 +Very long chain fatty acid accumulation 3 7 2.1288203950502784 0.0332691228693053 2.1820388349514563 5.470873786407767 0.5842375287416242 0.4040997577361238 1.517972497559233 1.851692013853064 1.0678239713607651 0.3118623380771133 0.0949181274262904 1.0 0.152955667850895 0.3400030327298383 0.0468003866103798 +Abnormal femoral neck morphology 11 38 2.126354788701366 0.0334737292623659 9.25242718446602 36.74029126213592 0.6712343390867015 0.4697291762664369 3.621586968033212 4.796644044529848 0.9043918120717824 0.3346762025558714 0.0050083794869595 1.0 0.0820650305700749 0.013435076878633 0.0048786043923336 +Abnormal circulating non proteinogenic amino acid concentration 3 8 2.125561943916826 0.0335397511767079 2.162621359223301 6.968446601941747 0.7521093084296674 0.2992197670299059 1.410866607722538 1.225329167014724 1.1887948503174883 0.2730524920497975 0.0009203602780865 0.0697581245313758 0.1362380906066266 0.000366006536683 0.0049176108076387 +Urinary glycosaminoglycan excretion 4 7 2.123672950898547 0.0336975007335862 2.9490291262135924 6.563106796116505 0.4749855796693131 0.2196485727407601 1.2846457065606351 0.9261036754709504 1.6390629541794843 0.2603486997442626 0.009996551282915 1.0 0.1362380906066266 0.0050923434600555 0.0005338561483377 +Fasciculations 10 39 2.1209168448226765 0.0339288008471341 9.201456310679612 36.5 0.4731561459207285 0.4826265043963199 3.4648999783170837 3.557775567723639 1.0532476984865673 0.3454376907067654 0.0055954786793863 0.2870659866655126 0.0304335118961749 0.0884683246757208 0.000515507866575 +Abnormality of the biliary system 26 117 2.1203756001558296 0.0339743827110119 24.728155339805824 113.4878640776699 0.4226772043353868 0.5416117734931738 8.513489210598458 10.938368752781027 1.0946055307638114 0.3805906621326833 0.0066130126839941 0.0357341306751934 0.0037185713088727 0.0237553797940069 0.0001587859857691 +Progressive neurologic deterioration 9 21 2.114823234278047 0.0344450158428628 6.75 20.466019417475728 0.5813429756502071 0.2930928839947513 2.6727908035631316 1.300228015706032 1.5791549964390388 0.3142214461904322 0.0018964045160623 1.0 0.0082729445560879 0.0035757213036434 0.0001817739981452 +Abnormal full field electroretinogram 2 7 2.1129811683396884 0.0346023797326384 1.7985436893203883 7.135922330097087 0.8897551200199579 0.2742817695009352 1.2050451450005106 0.7670210145007976 1.1859557261264115 0.267107203595487 0.0362941385189957 0.0058373227860703 0.0224191931510111 0.0193169154759243 0.0271057364081029 +Abnormal light and dark adapted electroretinogram 2 7 2.1129811683396884 0.0346023797326384 1.7985436893203883 7.135922330097087 0.8897551200199579 0.2742817695009352 1.2050451450005106 0.7670210145007976 1.1859557261264115 0.267107203595487 0.0223651585611987 0.0040679264544396 0.0158256043387446 0.0116756742779249 0.01439805670462 +Tetraparesis 10 36 2.1119561378115512 0.0346902116157843 7.587378640776699 35.63592233009709 0.2185556182972484 0.6062059087017716 4.06496228410477 3.1735360318458175 0.8238612160205229 0.3182737840492536 0.0165713984509496 0.0080720369936571 0.009674915769008 0.004652372899716 0.002896721501077 +Spastic tetraparesis 6 25 2.10538774526917 0.0352575696622465 5.230582524271845 24.473300970873787 0.2090726806611247 0.5676748710859181 3.263171465029081 2.380496353704214 0.915257703448056 0.3194790998285025 0.0230436364337774 0.0266825716175236 0.0146485330026984 0.0087768454005906 0.0136894768366188 +Nasogastric tube feeding in infancy 3 10 2.104842923457146 0.0353049834086467 3.0097087378640777 8.495145631067961 1.0003947416243104 0.2675726652756056 1.510449978803449 1.1668877069106371 1.1016283190777107 0.2724768109071007 0.2242694495123563 1.0 0.2467424796819782 0.154226710893935 0.0501437556032915 +Abnormal lower motor neuron morphology 3 9 2.0977509451188907 0.0359271519449744 2.1771844660194173 8.701456310679612 0.8468629004048428 0.2893246976958152 1.3759952567341256 1.207057649999096 1.1584035743641086 0.2695692447215745 0.1789878690111356 0.1135912525516411 0.2166826538338764 0.1211421538065826 0.031065887399213 +Poor wound healing 1 5 2.0959842018270822 0.0360835924004605 1.779126213592233 5.665048543689321 0.5228882363471196 0.4337271195964888 1.28178092640413 0.7564876346199129 0.966090262178579 0.3006630201307761 0.0589581135287866 1.0 0.1191939669275513 0.2721697661507766 0.129364196063302 +Retinal degeneration 12 60 2.092867117122477 0.0363610183506208 11.890776699029129 56.16747572815534 0.249024006789609 0.518990175786131 4.729602333356375 6.268553853518324 1.1275766261124216 0.3578686327011649 0.0690709082595767 0.2319080516082868 0.0374080587742306 0.0891710179820889 0.0795792405064971 +Abnormal thoracic spine morphology 5 30 2.090069154020836 0.0366115880780195 6.558252427184466 27.104368932038835 0.8238927765093872 0.4398474942511601 2.7009535990178555 2.5649391710658156 0.8855000478727516 0.3360788168488923 0.0117601836994874 1.0 0.0222198796395938 0.0036888619541724 0.0099258782765325 +Sensory axonal neuropathy 4 13 2.086846192891629 0.0369020400392241 3.9975728155339807 14.679611650485436 0.7278248103953019 0.4694895664907109 2.2409459540492587 2.061969989484369 0.8093416738396336 0.3127535543746148 0.0114133203420679 0.1305522111527444 0.031964215627013 0.0048864602536943 0.012033886898071 +Depression 22 108 2.086788416884108 0.0369072646432504 21.866504854368937 102.23058252427184 0.3844987984674038 0.6518312597777748 6.663852964137664 9.29780935941184 0.7952008671962957 0.3502437860603438 0.1040370943569234 0.3547775780934344 0.1072278650542487 0.0492865033304916 0.0038393191644127 +Xerostomia 6 16 2.081922823362031 0.0373495196952771 4.225728155339806 15.218446601941748 0.9400183964262208 0.3676147626670514 2.1144482637513415 1.4041718405623504 0.8665256443899695 0.3037909474394171 0.1044844728227304 1.0 1.0 0.0591065206713347 0.0082637154660588 +Dysostosis multiplex 5 10 2.0811442977383696 0.0374207002486659 3.983009708737864 7.990291262135922 0.4150973501220912 0.1595724105588133 1.65382835361071 1.246316090990369 1.8479195153421644 0.2123242141003258 0.003487974789979 1.0 0.1854358412925483 0.0014320459890063 0.0003730251283681 +Reduced visual acuity 40 127 2.081128794221943 0.0374221189059509 25.553398058252423 114.88106796116504 0.4786956822479749 0.5063280215354549 8.433035081523723 11.838637206126975 1.2158495541746812 0.3830713742278179 0.0646823625822969 0.2273563825849989 0.4279332102467005 0.1264391800925789 0.0013097598655908 +Atrophy degeneration involving the corticospinal tracts 4 13 2.0737825744466214 0.0380995082345476 3.046116504854369 12.830097087378642 0.5862844965366169 0.5076242219583529 1.6751494545754666 1.7194679099903734 0.8501612708621024 0.329209288406221 0.1044844728227304 0.1635258499471353 0.3034780999558708 0.0591065206713347 0.0321953433845534 +Erythroderma 1 9 2.071860733144015 0.0382784308448547 2.150485436893204 8.606796116504855 0.2398808158041126 0.437655956978666 1.6359655434930938 1.569042880348803 1.033421625926718 0.2823506274587667 0.1569285299286972 0.0053672672920639 0.0206800818926893 0.1053546389470493 0.3089323218960526 +Capillary hemangioma 3 8 2.071765564812248 0.038287309508217 2.533980582524272 7.133495145631068 1.1471796350867234 0.2683759543048971 1.4112277515033682 1.3471092449900268 0.9767941621718578 0.2786452679412407 0.2702860533260499 1.0 1.0 0.1887844423268079 0.0743636419116672 +Aplasia hypoplasia involving the vertebral column 6 14 2.06828242294181 0.0386134736125176 4.679611650485437 14.847087378640778 0.8883735186508074 0.3527358077962234 2.3127489306396716 2.051146083169333 0.9597872998017484 0.2871451112966173 0.0424943645739179 1.0 0.3432341150980792 0.0846608217542885 0.0043384264527958 +Psoriasiform dermatitis 3 5 2.067509901309775 0.0386861321916198 1.2766990291262137 3.1893203883495147 0.8942506955350448 0.3273575056985228 0.8596345897316691 0.9644569498069456 1.1033447304379942 0.2695864994971718 0.3939928003913119 1.0 1.0 0.3236592382947187 0.039942155971048 +Frontotemporal dementia 5 11 2.066492716682378 0.0387819794152706 3.4344660194174756 10.344660194174756 0.5931524822816645 0.4529040772840182 1.8896952177098856 1.3751065734754873 0.9402199282689112 0.308701646569884 0.1901881882333377 1.0 1.0 0.1292409073430241 0.0075122167669424 +Abnormality of the lymphatic system 33 146 2.063724724804161 0.039043823716734 29.699029126213592 145.21601941747574 0.1994066708674118 0.5892027724934705 8.709814742221091 14.879269336886908 1.105110161252099 0.3641956683310547 0.0536718112907537 0.3563220663563233 0.0644363380194152 0.0677808228611229 0.005143601682426 +Microcornea 7 33 2.062542969456087 0.0391560710081584 6.223300970873787 27.9004854368932 0.466347775811294 0.5952452592567805 3.105529171282791 3.8348554430650177 0.7011549915883155 0.306673764898096 0.1949605982179135 0.3837477700868037 0.2534337902702077 0.435424260519051 0.1132746653755905 +Peripheral neuropathy 34 161 2.060244983644721 0.0393751264995525 35.351941747572816 163.45388349514562 0.1946932918129254 0.7636805448429885 12.089268333980163 16.292839259381946 0.6495087855673025 0.3069195916326133 0.004828379464777 0.0309865229610318 0.0093565189084703 0.0078332857853569 0.0002333250235093 +Dilatation of the cerebral artery 2 9 2.059450259281428 0.0394511253308551 2.6966019417475726 10.432038834951456 0.2566150509415247 0.5672366245101242 2.0103344905462186 1.297025244137037 0.8079922324978768 0.2931077113272053 0.6443853960611703 1.0 1.0 0.5539124029112868 0.2151867556135544 +Abnormality of temperature regulation 21 104 2.058560597827406 0.0395363506087214 19.25485436893204 102.82038834951456 0.3970293406250321 0.5993116835261848 7.1176384711487035 9.956544993053525 0.8850362554833304 0.3476784016267602 0.2782509537164095 0.0121701622195073 0.0221968515193832 0.263713305232474 0.0137886172364963 +Thickened nuchal skin fold 6 15 2.057397824195902 0.0396479742765567 3.3470873786407767 12.199029126213592 0.2980345506064389 0.5598774001369132 1.8884976980318957 2.7780692864499823 0.7856135549850971 0.277101568485148 0.1990322211305738 0.2145132052152406 0.0846927074465841 0.3407321567572847 0.0100459976774882 +Vitiligo 1 7 2.055041394494371 0.0398750066831177 1.75 6.893203883495145 0.5228034908965178 0.4514214081097454 1.549545815072826 0.7902638291080828 0.9503325655279016 0.3007892778972581 0.1461066830947072 0.1006582454154426 0.1933613304033528 0.097689242801984 0.2906426697670494 +Left ventricular hypertrophy 14 28 2.0526593555983097 0.0401056265611867 7.567961165048544 23.54126213592233 0.6997255266541987 0.4097452846499351 3.537969183053948 3.034709621147107 1.2051726960058406 0.3398649994618895 0.1453921098990882 0.2731012734555347 0.475884211749649 0.4755559518983523 0.0405116355371222 +Abnormality of the tarsal bones 8 30 2.051322172938623 0.0402355825733302 7.135922330097087 26.50242718446602 0.598228998535255 0.5095033527659901 3.3211547403728976 3.593750499473341 0.86584218888204 0.3274398125512684 0.1041194110416074 0.3241278561278478 0.0439828576930944 0.0457838139336303 0.0164862192765472 +Abnormality of the larynx 17 51 2.049127253606399 0.0404496731491734 10.682038834951456 46.699029126213595 0.7426785971038559 0.4816723930500222 4.067795342682343 4.403407664230521 0.9382180075001202 0.3633154044529258 0.172043932464479 0.5123592328378659 0.422683272943231 0.1480406608198908 0.0567909348296337 +Spastic paraparesis 5 20 2.0482259560866907 0.0405378642670504 5.478155339805825 20.550970873786408 0.6522343609765672 0.5124278683317688 2.4725696108954978 1.913118744158018 0.8986801667257259 0.3474119612866397 0.002140052762423 1.0 0.0678620701894922 0.0211003003498726 0.018870184963526 +Increased circulating antibody level 2 15 2.0469736566334618 0.0406606711513766 3.2402912621359223 15.145631067961164 0.5908116743587006 0.4340890712285613 1.9578142936372311 2.533878285328643 0.9673694377645128 0.2975830104493745 0.2313661588599403 0.0276250495673642 0.0154029461510805 0.1411134338084059 0.4925971625249474 +Chronic diarrhea 5 17 2.04611086486985 0.0407454642794022 4.514563106796117 18.550970873786408 0.2309588263877121 0.4319883908654413 2.0282666456418785 2.0703229027090826 1.177819281609388 0.3206617066576645 0.1755702870596285 0.0213158974187442 0.0761270368947914 0.1038817567329197 0.193832289989472 +Cerebral inclusion bodies 6 14 2.0460978524102376 0.0407467442594042 3.844660194174758 13.655339805825244 0.5051551663301821 0.4226246963159299 1.8115448621120656 1.6612796655742368 1.090041660052819 0.3107400387490911 0.003134273726162 1.0 0.2756599666896902 0.0444854600227105 0.0008750939624126 +Skeletal dysplasia 13 48 2.044483764184158 0.0409057797292267 9.847087378640778 42.45631067961165 0.4246740768550524 0.5844005076424144 4.1773099838416154 5.798018910120849 0.8069396415917074 0.3278424633591593 0.0456852218795341 1.0 0.3572711778500047 0.0918582333412919 0.0039580527577536 +Vertebral segmentation defect 8 31 2.0439807966461103 0.0409554442844479 7.145631067961165 29.46359223300971 0.2855096581136558 0.647918071850007 3.2348459755061563 2.7352667480961785 0.6895741990154806 0.2948781739840204 0.2058169936744196 0.389715394886943 0.6321995046854245 0.2320879157008667 0.0598757179226396 +Nephropathy 9 19 2.039717801823967 0.0413784408115454 4.953883495145631 20.679611650485437 0.6460031144846833 0.4125859609731191 2.359716427347698 2.5216098734814283 1.0719980152629416 0.3150102108345451 0.0494208680910316 0.0388410242837302 0.1312354716944213 0.0715305134437747 0.0953101243725822 +Abnormal visual fixation 1 8 2.0372781929206663 0.0416221718722373 2.1237864077669903 6.516990291262136 0.3282606812074232 0.2644845064785266 1.2333226229346623 1.2136771814929264 1.4687997702265556 0.2650474123539905 0.1046893250830714 0.083126337411673 0.012905013470629 0.0688460117016781 0.2173267675800807 +Abnormality of the tongue 23 98 2.0362593734136487 0.0417243170523209 22.424757281553397 89.52912621359224 0.5421010507218363 0.5607339999720974 6.938472222740965 9.436122816051313 0.9593463898963266 0.3606735981467843 0.0759121753753933 0.7337058657898887 0.1233938668694852 0.2084272349212674 0.0127879151493013 +Psychotic mentation 2 5 2.03598134436173 0.0417522286198892 1.3810679611650485 5.213592233009709 0.5390214400079423 0.4488271579257555 1.1095047549274055 1.177462183235361 0.9736664818107128 0.3100249330671143 0.0762554308819813 0.0697581245313758 0.1362380906066266 0.0495157384890535 0.0336357980244025 +Myoclonic seizure 18 55 2.0320678102277605 0.042146791600498 11.686893203883496 52.98543689320388 0.3944988422537482 0.4078474078990697 4.250245345088794 5.776566450302065 1.383306240067707 0.3629970156021384 0.0153837230416424 0.1570363283812061 0.014090869270841 0.0259252536664186 0.0122430856112643 +Flat face 8 27 2.028139524228413 0.0425460100189141 6.66747572815534 24.08495145631068 0.4902055675682596 0.5473999825637093 3.284800305273881 3.633055728953568 0.8018127166907104 0.315636792407103 0.2192171731714846 0.314211533829163 0.0400324838097305 0.2908433959862969 0.0130876591736213 +Increased serum lactate 27 109 2.0213631815541744 0.0432421831382459 28.99514563106796 103.9126213592233 0.2156320103365802 0.4835633979758786 13.01418105275692 9.239117761559864 1.4606133548257267 0.3784654233889921 2.3449960022392832e-05 0.0093664892176293 0.0002692057281971 1.824781631619224e-05 9.139722832590314e-07 +Hypoplasia of the musculature 1 5 2.0202586801124265 0.0433565623930309 1.412621359223301 5.393203883495145 0.6491558839366509 0.4339241341629252 1.0724420559765822 0.8594152602202743 0.8694942858597294 0.2925094147190523 0.0762554308819813 0.0697581245313758 0.0090253131212995 0.0495157384890535 0.16360549489043 +Blurred vision 3 5 2.017359057555033 0.0436580566462196 1.4684466019417477 4.449029126213592 0.7772225957067546 0.3401357669580369 0.986055451759567 0.9450042528934012 1.0938682095756602 0.2939628040587096 0.1147181499347949 0.0875404472016038 0.1693528922958147 0.0757571260003459 0.0621142898948071 +Parkinsonism 12 30 2.0103846717567286 0.0443904915306996 7.453883495145631 30.097087378640776 0.7249761134976155 0.4663275088289313 3.116711838694066 3.708464636913605 0.8967824567735009 0.3291722600978801 0.1255789576248624 1.0 0.203284502277127 0.0566012047710065 0.0235212982094472 +Posterior embryotoxon 10 22 2.008688980957918 0.0445701280318142 5.400485436893204 18.211165048543688 0.5603270949007155 0.5260153972846668 2.4736082204804974 3.2255911781388433 0.9025074564453092 0.3301763927361542 0.0754715823975887 1.0 0.3986935444378103 0.3583320648627024 0.012384049701444 +Hepatomegaly 58 175 2.007753972724356 0.0446694421107678 39.728155339805824 169.55582524271844 0.4089837357771489 0.5280564448988146 14.21621812446184 16.25283515367601 1.2317505616434137 0.3902252758923212 5.779969903027157e-05 0.0100052333541818 0.00034436275741 0.000159820251737 1.0156657614966937e-07 +Recurrent aspiration pneumonia 3 6 2.0028697336624863 0.045191272504149 2.0606796116504853 6.25 0.3948833569251968 0.2988616259147967 1.2222482563963537 0.6632700690261994 1.354266830500057 0.2888538147928982 0.0854309101739854 0.0742352733278267 0.0102498345034834 0.0557098434243155 0.1812716861639223 +Wide anterior fontanel 9 29 1.9985505174674796 0.045657008856569 6.883495145631068 22.87135922330097 0.5984883047357004 0.51093763506043 3.004207311482479 3.16541613655465 0.8343647618961921 0.3244934138131808 0.036924392931165 0.2516504230112798 0.0203848430395501 0.1760149897618766 0.0022883393024557 +Progressive psychomotor deterioration 6 8 1.993358192570369 0.0462222384103263 3.349514563106796 8.320388349514563 0.5379615244672443 0.2176134167318772 1.5053866894387542 0.6226094824456632 1.5848775742530583 0.2457660654605461 0.050899384243609 1.0 0.1105474823156849 0.032628233248221 0.0001590313802548 +Distal peripheral sensory neuropathy 1 5 1.9928819521174228 0.0462743750388274 1.4344660194174756 4.679611650485437 0.5764101798236201 0.4022081089263229 1.2299169031488042 0.9421478480744178 1.0445462753474666 0.3013565434873159 0.050899384243609 0.0561990347849709 0.1105474823156849 0.032628233248221 0.1129571724371578 +Achilles tendon contracture 6 12 1.9921752028532604 0.0463518379765113 4.004854368932039 11.279126213592232 0.5734466657319717 0.5136155316960331 2.137273403229174 1.1955626751800683 0.8553039294976645 0.3252433518045028 0.0636937738164182 1.0 1.0 0.5198923492291299 0.0138780941766985 +Duplication involving bones of the feet 12 27 1.9904344887741412 0.0465430938580875 5.509708737864078 20.026699029126213 0.8286726631699953 0.4291828835649511 2.4019415513574103 3.6259268352065384 0.9263895151182656 0.3280751122544665 0.619336326031036 0.3926779415133941 0.6358068208259667 0.4544885019007071 0.3858723616319152 +Abnormality of chorioretinal pigmentation 1 5 1.986440644034484 0.0469844174048763 1.3106796116504855 4.313106796116505 0.4406186553708134 0.5018582173303782 1.0523125362981924 0.6872790435770761 0.901171785399864 0.3030431868661924 0.0234121875355895 1.0 1.0 0.1775366954381628 0.0544194668097373 +Abnormal pupillary function 2 6 1.9856235421480035 0.04707514039388 1.7985436893203883 6.25 0.9459174425459445 0.2892194993230557 1.1928988171245156 1.7202745886032773 1.109204161812943 0.2732247962160634 0.2472401890511195 0.1389130578490434 0.0361556764775263 0.1713585638073601 0.1897708582520546 +Abnormal circulating long chain fatty acid concentration 2 6 1.9847604319274408 0.0471711316904654 2.0728155339805827 4.861650485436893 1.0288291622755297 0.284696092465088 1.384567800831184 1.563474222630441 1.0358408470651057 0.2764983518284591 0.0949181274262904 1.0 0.152955667850895 0.3400030327298383 0.0468003866103798 +Atrophy degeneration involving the caudate nucleus 1 6 1.983911851690636 0.0472656674732818 1.2888349514563109 4.283980582524272 0.3751529128205025 0.4147621281846377 1.0481475114547032 1.0836094304135666 1.1513114797047737 0.3142236199023666 0.050899384243609 0.0561990347849709 0.1105474823156849 0.032628233248221 0.1129571724371578 +Emg neuropathic changes 8 24 1.9789770486163556 0.0478185903946317 6.915048543689321 24.58252427184466 0.5887299592537784 0.4208819793990807 3.046574831105746 2.544837804909062 1.1306803597402475 0.3318248802653038 0.0489414442151608 0.0196403757049561 0.0009182879541791 0.0227330174276438 0.0002619380543045 +Dysesthesia 1 6 1.974639143758324 0.0483091135872761 1.3762135922330097 5.62621359223301 0.7008159231697947 0.4002775950461114 1.0271637039764925 1.2192199611233647 0.9765666303617 0.3018854922290938 0.0432787476847939 0.0516364610584135 0.0048484802924912 0.0276231155809849 0.0971506673250001 +Personality changes 5 18 1.9681653424105203 0.0490490165418677 4.235436893203883 16.20873786407767 0.716641708966708 0.4361664780008399 2.2513009299259603 2.2727002372019856 0.9467269936740988 0.3182188186141179 0.0286114952840351 0.1675604235637086 0.0523352985295366 0.0128293519549119 0.0094203676276074 +Abnormality of the peripheral nervous system 25 111 1.967153018955307 0.0491655724274868 21.851941747572816 100.3252427184466 0.4924736649059071 0.6070149484118681 7.60428603700104 12.016414489110195 0.8367540963076672 0.3602458415795309 0.0393483193812018 0.4166947181988512 0.1588739960757451 0.0538661903889369 0.0024231154685836 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1d27d2de669f87d129ceceb658eeff59dd52c8ad --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 4658, + "title": "Average number of proteins per term", + "value": 24.77114641477029 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b854274425a59b57ea28dc8cf15d776b992dc8ef --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..706e480e06f16394ebc4d5727da149b7c4c22d7a --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1722 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mental deterioration 0.5615368565047328 4.635138328786991 3.5669886895295377e-06 0.0164777940853854 0.0007618502754284 98 P50897,Q14108,P00846,O75306,Q5XKP0,P17900,Q13510,P35637,P16278,P00403,O15118,P22626,P27544,P05067,P07602,P61916,Q9BQE5,Q9Y287,P54802,Q9Y487,O60313,P04062,O75503,O43464,O60220,Q9NQZ5,O95470,P31483,Q9NZJ7,Q13501,P03886,Q10713,P06865,Q05639 34 +Dementia 0.6355637409922646 4.196289769994869 2.7132307339750028e-05 0.1187236302132764 0.0014042476398728 59 Q14108,P00846,P17900,Q13510,P35637,P00403,O15118,P22626,P27544,P05067,P07602,P61916,Q9Y287,Q9Y487,O60313,P04062,O43464,O60220,Q9NQZ5,P31483,Q9NZJ7,Q13501,P03886,P06865 24 +Cognitive impairment 0.4781180416593104 4.135087963548578 3.548187003810099e-05 0.1523415392187477 0.0017131764111382 173 P07196,P50897,Q14108,P01889,Q6DKK2,Q9Y2R0,Q9H9S5,P00846,P40855,O75306,Q5XKP0,Q13510,P17900,P35637,P16278,Q99720,P00403,O15118,P31749,P22626,P27544,P05067,P07602,P61916,Q9BQE5,Q9NZ08,Q9Y287,P54802,Q9Y487,Q9Y5Y5,O60313,P04062,O95831,O75503,O43464,O60220,Q9NQZ5,O95470,P31483,Q9Y619,Q9NZJ7,Q13501,P03886,Q10713,P06865,Q9H6K4,Q05639,O75381,P06280 49 +Intracellular accumulation of autofluorescent lipopigment storage material 0.9742527374963006 4.069362377521793 4.714197603106207e-05 0.1971541093122679 0.0018432020612914 2 O75503 1 +Low plasma citrulline 0.9689257176679492 4.044862123941568 5.235392630065227e-05 0.2164112678157494 0.0018932286868581 2 P00846 1 +Multiple glomerular cysts 0.9689257176679492 4.044862123941568 5.235392630065227e-05 0.2164112678157494 0.0018932286868581 2 P00846 1 +Leber optic atrophy 0.9689257176679492 4.044862123941568 5.235392630065227e-05 0.2164112678157494 0.0018932286868581 2 P00846 1 +Retinal arterial tortuosity 0.9689257176679492 4.044862123941568 5.235392630065227e-05 0.2164112678157494 0.0018932286868581 2 P00846 1 +Abnormality of the glenoid fossa 0.9630068067475586 4.01755325341744 5.880554862813803e-05 0.2396103652119337 0.0018932286868581 2 Q9Y619 1 +Asymmetric septal hypertrophy 0.9576797869192072 3.992896949376924 6.527093941266493e-05 0.2621700923939544 0.0018932286868581 2 P54802 1 +Atlantoaxial instability 0.952648712636875 3.969541801322466 7.201097346776208e-05 0.2849760155812891 0.0018932286868581 2 Q7RTS9 1 +Cerebral amyloid angiopathy 0.9443622373483278 3.9309278997994506 8.461864745479275e-05 0.3257608015318038 0.0019748758045424 2 P05067 1 +Hyporeflexia of upper limbs 0.9419946729801724 3.9198616066090968 8.859983161046969e-05 0.3381499764292155 0.0020131610519101 2 Q9NR77 1 +Ketotic hypoglycemia 0.9047055341817114 3.743544752471296 0.000181442268087 0.5705434761562607 0.0032257942166007 2 Q13423 1 +Alveolar ridge overgrowth 0.8973068955312234 3.708099117580661 0.000208820923564 0.6219729159073386 0.0036043085538481 2 P98175 1 +Abnormal calcification of the carpal bones 0.8907960935187945 3.676777379824307 0.0002361989992532 0.6672437016857158 0.0039862860091355 2 Q15125 1 +Enlargement of the wrists 0.8907960935187941 3.676777379824307 0.0002361989992532 0.6672437016857158 0.0039862860091355 2 O95831 1 +Mitral stenosis 0.9635381668446804 3.6515504124336218 0.0002606619172633 0.7030885940585045 0.0042012567841273 3 P04062 1 +Aortic valve calcification 0.9635381668446804 3.6515504124336218 0.0002606619172633 0.7030885940585045 0.0042012567841273 3 P04062 1 +Abnormal sacroiliac joint morphology 0.8831015093222854 3.639602828291815 0.0002730588820814 0.7197524494440658 0.0043409838659903 2 P22413 1 +Enthesitis 0.8831015093222854 3.639602828291815 0.0002730588820814 0.7197524494440658 0.0043409838659903 2 P22413 1 +Episodic respiratory distress 0.9598942834006592 3.635246829609673 0.0002777146078285 0.7257662136651342 0.004355537519412 3 P00846 1 +Flaring of rib cage 0.8789582716780127 3.6195142888690848 0.000295156513306 0.7471710169805375 0.0045675715580713 2 Q7RTS9 1 +Thin bony cortex 0.8768866528558754 3.609451137931989 0.00030684556345 0.7605728214561266 0.0047016007715473 2 Q9NSD9 1 +Hemihypertrophy 0.8768866528558753 3.609451137931989 0.00030684556345 0.7605728214561266 0.0047016007715473 2 P31751 1 +Abnormal pelvis bone morphology 0.8754069251257783 3.602255439258639 0.0003154681429984 0.7700014883742982 0.0047958944591302 2 Q7RTS9 1 +Abnormality of the radioulnar joints 0.8739271973956799 3.595053281020921 0.0003243251942091 0.7793001814195366 0.0047958944591302 2 P16435 1 +Abnormal tarsal ossification 0.8739271973956815 3.595053281020921 0.0003243251942091 0.7793001814195366 0.0047958944591302 2 Q15125 1 +Radioulnar dislocation 0.8739271973956799 3.595053281020921 0.0003243251942091 0.7793001814195366 0.0047958944591302 2 P16435 1 +Vascular tortuosity 0.9487862640615748 3.58534250097569 0.0003366361158445 0.7916039697846713 0.004962186796215 3 P00846,P03886 2 +Recurrent pharyngitis 0.8564664101805279 3.5095754259113936 0.0004488227408612 0.8764470692215437 0.0062406457520345 2 P01889 1 +Gastrointestinal infarctions 0.8564664101805279 3.5095754259113936 0.0004488227408612 0.8764470692215437 0.0062406457520345 2 P01889 1 +Glossitis 0.8564664101805279 3.5095754259113936 0.0004488227408612 0.8764470692215437 0.0062406457520345 2 P01889 1 +Facial hyperostosis 0.8443326427937274 3.449633329741995 0.0005613484491584 0.9268684384590308 0.0072431573458146 2 P31749 1 +Humeroradial synostosis 0.8443326427937274 3.449633329741995 0.0005613484491584 0.9268684384590308 0.0072431573458146 2 P16435 1 +Elbow ankylosis 0.8443326427937274 3.449633329741995 0.0005613484491584 0.9268684384590308 0.0072431573458146 2 P16435 1 +Chondrosarcoma 0.918590882178802 3.448099685640308 0.0005645456368257 0.9279500849475932 0.0072642363987134 3 P48735,Q92804 2 +Widened cerebral subarachnoid space 0.9168079988801864 3.439922388831216 0.0005818810221593 0.9335423697141648 0.0074257583595026 3 P00403 1 +Hypergranulosis 0.839005622965376 3.4231746095188456 0.0006189430514016 0.9440853758050776 0.0076239879910165 2 P22413 1 +Retinal thinning 0.8372299496892593 3.4143355224980856 0.000639377848987 0.9491652209260106 0.0076956641358699 2 P51648 1 +Choroidal neovascularization 0.8372299496892587 3.4143355224980856 0.000639377848987 0.9491652209260106 0.0076956641358699 2 P22413 1 +Abnormal optical coherence tomography 0.8372299496892587 3.4143355224980856 0.000639377848987 0.9491652209260106 0.0076956641358699 2 Q96S66 1 +Photoreceptor layer loss on macular oct 0.8372299496892587 3.4143355224980856 0.000639377848987 0.9491652209260106 0.0076956641358699 2 Q96S66 1 +Abnormal morphology of the choroidal vasculature 0.8372299496892587 3.4143355224980856 0.000639377848987 0.9491652209260106 0.0076956641358699 2 P22413 1 +Sclerotic vertebral endplates 0.8342704942290635 3.3995819313572606 0.0006748895683159 0.9569200199669978 0.0078787859880094 2 P22413 1 +Hip osteoarthritis 0.8342704942290633 3.3995819313572606 0.0006748895683159 0.9569200199669978 0.0078787859880094 2 P01889 1 +Joint hemorrhage 0.8330867120449854 3.3936728519628576 0.0006896202202151 0.959778721676566 0.0080306274644051 2 P38435 1 +Asymmetry of the thorax 0.8259840189405169 3.358126200565207 0.0007847277698667 0.9741823495646772 0.008829135149853 2 P31749 1 +Abnormal vertebral morphology 0.4506182490919466 3.350479595799404 0.0008067175248585 0.9766977823243018 0.0090546752549178 115 P10619,P00813,Q14108,P61978,Q15125,P15586,Q9H9S5,Q96HY6,O75874,P16278,P31749,O75718,P16435,Q14739,Q8WVQ1,P48735,P54802,Q32P28,P04062,Q8NCH0,Q8WXW3,Q9Y4P3,O95831,Q9Y619,O95202,P04066,O75845,Q9UHX1,Q10713,P22413,Q7RTS9 31 +Decreased light and dark adapted electroretinogram amplitude 0.8922265148944044 3.3263191944300763 0.0008800109110196 0.983442158863744 0.0096222789284729 3 P50897 1 +Ragged red muscle fibers 0.7349149680895695 3.3217617717301513 0.0008945103117976 0.984524446454196 0.0097351145615735 20 Q70HW3,Q9H2D1,P00846,O95831,P00403 5 +Abnormality of cartilage of external ear 0.8817220151976498 3.2772768961192664 0.0010481352645985 0.99243917117692 0.0108493645833336 3 Q7LGA3 1 +Vaginal atresia 0.8085232317253646 3.2700612933401416 0.0010752418328356 0.9933369040879744 0.0110318864699309 2 P16435 1 +Finger agnosia 0.8076353950873063 3.265557322584708 0.0010924889096353 0.993851794961143 0.0110631526030196 2 P05067 1 +Angiokeratoma 0.8792184724689116 3.265544141084466 0.0010925397589927 0.993853252622162 0.0110631526030196 3 P04066,P06280 2 +Sea blue histiocytosis 0.8792184724689129 3.265544141084466 0.0010925397589927 0.993853252622162 0.0110631526030196 3 O15118,P61916 2 +Prominent sternum 0.8792184724689086 3.2655441410844084 0.0010925397589929 0.9938532526221684 0.0110631526030196 3 O95831,Q7RTS9 2 +Biliary tract abnormality 0.6957041509034337 3.2608262377381823 0.0011108809348483 0.9943571140005044 0.0112057354822992 25 Q14108,P04062,Q14739,P09601,Q9NZJ7,O95202,P07602,Q10713,Q9NSD9,Q5XKP0,P14174 11 +Angioid streaks of the fundus 0.877146240378925 3.255819677480072 0.0011306553477836 0.9948541885539428 0.0112550608059619 3 P38435,P22413 2 +Visceral angiomatosis 0.8771462403789202 3.255819677480016 0.0011306553477838 0.9948541885539482 0.0112550608059619 3 O75874,P48735 2 +Hemangiomatosis 0.8771462403789202 3.255819677480016 0.0011306553477838 0.9948541885539482 0.0112550608059619 3 O75874,P48735 2 +Lymphangioma 0.8771462403789202 3.255819677480016 0.0011306553477838 0.9948541885539482 0.0112550608059619 3 O75874,P48735 2 +Abnormality of extrapyramidal motor function 0.4889200638890247 3.2538526424581766 0.0011385132022687 0.9950393359589164 0.0112960438131938 75 Q9BPX6,Q6DKK2,Q9H9P8,P16278,P17900,P35637,Q99720,P05067,P07602,P04062,Q96JX3,Q9Y4P3,P61457,O43464,O14949,P98175,Q9NZJ7,Q9H0B6,Q13501,P06865,Q9H6K4 21 +Central heterochromia 0.8052678307191499 3.253534276803188 0.0011397897364107 0.9950687784623412 0.0112960438131938 2 P31749 1 +Impaired proprioception 0.6172427304860691 3.2361146074336933 0.0012116872412955 0.9964735421006684 0.0118580915001758 39 Q9NR77,Q9Y619,O75298,Q9H0B6,Q8IV08,P00846,Q9H6K4,O14773,P54802 9 +Ovotestis 0.7993489197987592 3.2233970757087245 0.0012667981444922 0.9972728180165216 0.0121414521749896 2 P53701 1 +Absent nipple 0.7984610831607006 3.2188666506360395 0.0012869831994002 0.997517846226034 0.0122949535360097 2 P10586 1 +Clumsiness 0.7073570963033151 3.2186194622922377 0.0012880930282466 0.99753066127247 0.0122949535360097 22 P31483,Q15067,Q9NR77,Q9NZJ7,Q13501,P07602,O43681,O75503,O14773,Q13510 10 +Proximal symphalangism 0.7937259544243883 3.1946607945902845 0.0013999527535881 0.9985344852348172 0.0131471369480115 2 P48651 1 +Sensorimotor neuropathy 0.6238858066573141 3.185725496576956 0.0014439152890415 0.998806204805433 0.0134842273945634 33 P07196,O60313,Q8N2K0,Q9NR77,Q9NZJ7,P03886,Q9Y2R0,P07602,P00846,O95831,P00403 11 +Agenesis of cerebellar vermis 0.7916543356022516 3.1840475720210653 0.0014523114244291 0.9988520571021652 0.0135297332299819 2 Q10713 1 +Abnormal biliary tract morphology 0.700510072257494 3.17444780398295 0.001501218882524 0.9990862299307646 0.0137651132968448 22 Q14108,P04062,Q14739,P09601,Q9NZJ7,P07602,Q10713,Q9NSD9,Q5XKP0,P14174 10 +Concentric hypertrophic cardiomyopathy 0.8563081321024997 3.1573690517211888 0.0015919972151108 0.9994017082497118 0.0143433714274395 3 P00403 1 +Polyneuropathy 0.768815742361397 3.1440542359458705 0.0016662455475806 0.9995768759366772 0.0148796502841218 17 O95721,Q9NZJ7,Q15041,P03886,P04066,P07602,P00846,O95831,Q8N2K0 9 +Vegetative state 0.8534635879218371 3.1438354185061783 0.0016674919382377 0.9995793294234876 0.0148796502841218 3 P07602,Q9NZJ7 2 +Progressive peripheral neuropathy 0.8534635879218371 3.1438354185061783 0.0016674919382377 0.9995793294234876 0.0148796502841218 3 P07602,Q9NZJ7 2 +Mitral valve calcification 0.9223226358101746 3.135069129709212 0.0017181361800959 0.999667862461176 0.0149740654876917 4 P04062 1 +Cardiac valve calcification 0.9223226358101746 3.135069129709212 0.0017181361800959 0.999667862461176 0.0149740654876917 4 P04062 1 +Myoclonus 0.4401179453436311 3.134953159945742 0.0017188155365708 0.9996689136336548 0.0149740654876917 101 P50897,Q14108,Q96CU9,Q01105,P00846,Q13510,P00403,P31749,P27544,Q9UBX3,P05067,P07602,P13073,P04062,Q8NI60,O75503,O14773,Q9NQZ5,Q9NZJ7,P03886,P00374,Q9H936,O75845,Q10713,Q05639 25 +Metaphyseal cupping 0.8512176194303838 3.133133468354078 0.0017295077785268 0.9996850264129838 0.0149740654876917 3 O95831 1 +Posterior fossa cyst 0.8503227857764708 3.1288656325124875 0.0017548253425498 0.99972012200937 0.0151369934177729 3 Q9UHX1 1 +Recurrent pancreatitis 0.8486991730136989 3.1211161299220427 0.0018016696977929 0.9997750756671776 0.015455207094511 3 P00403 1 +Palmoplantar hyperhidrosis 0.7771530038472951 3.109356719539181 0.001874951982167 0.9998402218156924 0.0159954694742381 2 P07858 1 +Palmar hyperhidrosis 0.7771530038472951 3.109356719539181 0.001874951982167 0.9998402218156924 0.0159954694742381 2 P07858 1 +Abnormal form of the vertebral bodies 0.4713925199023298 3.10676535136094 0.0018914646963339 0.9998520720752624 0.0160481649463087 88 P00813,Q15125,P15586,Q96HY6,O75874,P16278,P31749,P16435,Q14739,Q8WVQ1,P48735,P54802,Q32P28,Q8WXW3,Q9Y4P3,O95831,Q9Y619,O95202,P04066,O75845,Q9UHX1,Q10713,P22413,Q7RTS9 24 +Diaphyseal thickening 0.8445825932504412 3.1014340113679584 0.0019258579128182 0.9998740084049752 0.0163030375432957 3 Q14739,P08236 2 +Extra axial cerebrospinal fluid accumulation 0.7750813850251581 3.098629255411311 0.0019441814279852 0.9998843349182206 0.0163295266388594 2 Q03252 1 +Abnormal circulating cholesterol concentration 0.618372177080617 3.0828083542982414 0.002050571650128 0.9999296036565952 0.0170563620469576 32 Q8N511,Q9NZJ7,Q15125,O75845,P07602,P61916,Q15800,Q9NVI7,P50402,Q15392 10 +Abnormal enchondral ossification 0.6086428295644193 3.0684086102818204 0.0021520214072723 0.9999561579550408 0.0176480910476664 33 Q9Y5Y5,Q9UG56,Q9Y619,Q14739,Q15125,P38435,Q8WVQ1,O95202,P22413,Q96HY6,P40855,O75381,Q7RTS9 13 +Hyperesthesia 0.8367029842238151 3.06362471710221 0.0021867303556986 0.9999627158795455 0.0178698070120072 3 P07602 1 +Abnormal epiphyseal ossification 0.6935569116705956 3.061552938072722 0.0022019205169812 0.9999652681846058 0.0178997308343777 20 Q9Y5Y5,Q9UG56,Q14739,Q15125,P38435,Q96HY6,P40855,P08236,O75381,Q7RTS9 10 +Childhood onset sensorineural hearing impairment 0.7670908552826309 3.0571162478894474 0.0022347758918781 0.9999702069379528 0.0180721980978618 2 O60220 1 +Prelingual sensorineural hearing impairment 0.7670908552826309 3.0571162478894474 0.0022347758918781 0.9999702069379528 0.0180721980978618 2 O60220 1 +Osteopetrosis 0.8345174659561897 3.053106099677997 0.002264858450901 0.9999741105636194 0.0182579956113262 3 Q15392,P48651 2 +Abnormal pelvis bone ossification 0.7662030186445723 3.052490333865077 0.0022695104033829 0.999974666769553 0.0182579956113262 2 Q14739 1 +Lethal skeletal dysplasia 0.7662030186445723 3.052490333865077 0.0022695104033829 0.999974666769553 0.0182579956113262 2 Q14739 1 +Abnormal muscle fiber morphology 0.4677195149336383 3.0219929423869756 0.0025111640296209 0.9999918027614996 0.0195602040969469 73 P07196,P61978,Q9BPX6,Q9H9S5,P00846,O43676,P35637,Q99720,P00403,Q70HW3,P22626,Q9H2D1,P05067,P50402,O60313,Q8NI60,O95831,P31483,P03886,O14979 20 +Morphological abnormality of the pyramidal tract 0.6794480733165716 3.003044584885634 0.002672932695936 0.9999961490470088 0.0205454133624919 21 Q9Y619,O75298,Q9Y4P3,P00846,Q9H9P8,O95831,P35637 7 +Abnormal circulating lipid concentration 0.4677165275215337 2.989538236522491 0.0027939947524937 0.9999978122624158 0.0212307137962739 78 Q15125,P40855,O75880,Q14739,P22830,P07602,P61916,Q15800,P50402,Q9Y5Y5,Q8N511,P31751,O75844,Q15392,O95470,Q9NZJ7,O75845,Q9NVI7,O75381,P06280 20 +Retinal pigment epithelial mottling 0.8193512454715626 2.9797304140577845 0.00288502163472 0.9999985700244638 0.0218202419043215 3 P00846 1 +Crumpled long bones 0.7522935779816546 2.9796657187232816 0.0028856309602967 0.9999985740890324 0.0218202419043215 2 O75718 1 +Posterior polar cataract 0.8187861872933789 2.9769835980048285 0.0029109958315327 0.999998733423128 0.0219763672338405 3 Q9Y287 1 +Variable expressivity 0.4674408623921642 2.9748612113832755 0.0029312113296109 0.9999988475636956 0.022057483640271 80 P07196,Q70HW3,O95470,Q9NR77,P17900,Q9NZJ7,Q15125,P03886,Q8NI60,Q96JX3,P07602,Q9H9S5,Q6P4A7,Q13510,Q9H061,P00403 16 +Dysphagia 0.4081802512556737 2.9705488017849757 0.0029726817035078 0.9999990505407697 0.0221903066906082 139 Q05086,Q14108,P01889,Q01105,P15586,P00846,O75874,O75306,Q13510,P35637,Q99720,O15118,Q9NR77,Q14739,Q9GZY8,P05067,P07602,P61916,P48735,Q8IZA0,Q9Y5Y5,O60313,Q15067,P04062,Q96D71,O60220,Q9NZJ7,O75489,Q13501,P03886,Q9H936,Q9UHX1,Q05639 33 +Optic disc pallor 0.5266901322265584 2.9699751942345145 0.0029782379680562 0.9999990748699952 0.0221962119283299 53 Q13277,Q96CU9,P00846,O43676,O75306,Q9H061,P04439,Q9GZY8,Q6P4Q7,P51798,Q86Y39,Q9Y287,O95298,O60313,Q9UG56,Q9NPL8,O95831,O75489,Q9H0B6,P03886,Q10713,Q96S66,Q9H6K4 23 +Macrodactyly 0.7475584492453422 2.9547222354825604 0.0031295066861964 0.999999543692829 0.0231018100543633 2 P31749 1 +Phenotypic variability 0.4257417061745264 2.9522379710384365 0.0031547969671406 0.9999995945519484 0.0232162898009569 105 P07196,Q15125,Q9H9S5,P00846,P17900,Q13510,Q9H061,P00403,Q70HW3,Q9NR77,P36551,Q8WVQ1,P07602,Q8NI60,Q96JX3,Q6P4A7,O95470,Q9NZJ7,P03886,P00374,O14979 21 +Amelogenesis imperfecta 0.8114543690077216 2.941257318936287 0.0032688286704667 0.9999997620354772 0.0239029889278399 3 Q9HC07 1 +Cervical spinal canal stenosis 0.7443030482391273 2.937528390777074 0.0033083987794955 0.999999802211974 0.0241401098313314 2 Q9NSE4 1 +Bile duct proliferation 0.8103822052815222 2.936019573656835 0.0033245334421567 0.9999998165778102 0.0241963699586972 3 Q5XKP0 1 +Abnormality of the subungual region 0.7431192660550492 2.9312669207741315 0.0033758258475287 0.9999998556750428 0.0244931414295774 2 P16615 1 +Shagreen patch 0.7431192660550492 2.9312669207741315 0.0033758258475287 0.9999998556750428 0.0244931414295774 2 Q6NUK1 1 +Saccadic oscillation 0.80605409395307 2.9148410944037773 0.0035586968948877 0.9999999386073374 0.0253074963914307 3 P04062 1 +Opsoclonus 0.80605409395307 2.9148410944037773 0.0035586968948877 0.9999999386073374 0.0253074963914307 3 P04062 1 +Anomalous trichromacy 0.8046465954086169 2.9079418403046544 0.0036381599279073 0.9999999576565056 0.0257155522673636 3 Q9H6K4 1 +Tritanomaly 0.8046465954086169 2.9079418403046544 0.0036381599279073 0.9999999576565056 0.0257155522673636 3 Q9H6K4 1 +Action tremor 0.5120027364623359 2.900719111338061 0.0037230744549188 0.99999997153083 0.0260391603768946 55 Q14108,Q5T8D3,P00846,Q8IY17,O75306,P35637,Q99720,P31749,Q9NR77,Q5JRX3,P07602,O75569,Q15233,Q8TAB3,Q9Y287,Q9BUB7,O14773,Q8N2K0,P48637,Q9NZJ7,P03886,O43681,Q9Y4W6,Q9H6K4 24 +Hypotriglyceridemia 0.736904409588639 2.898313711294898 0.0037517511343809 0.9999999751030658 0.0260918126112593 2 Q9Y6B6 1 +Hypolipidemia 0.736904409588639 2.898313711294898 0.0037517511343809 0.9999999751030658 0.0260918126112593 2 Q9Y6B6 1 +Abnormal vascular physiology 0.5117316502646004 2.8980257048716047 0.0037551981114238 0.9999999755011014 0.0260918126112593 55 P31749,Q9NWM8,P06280,Q14108,O15460,P04062,Q14739,P03886,P01889,P20674,P05067,Q9Y4P3,P22413,Q71SY5,O75844,Q8IZA0,Q9NZ08,P00403 18 +Atlantoaxial abnormality 0.8693142128228568 2.89680722851256 0.0037698132003816 0.9999999771192952 0.0260918126112593 4 Q8NCH0,Q7RTS9 2 +Abnormal motor evoked potentials 0.7357206274045611 2.892021529437053 0.0038277171605898 0.9999999825463496 0.0263121966713874 2 P07196 1 +Centrocecal scotoma 0.8682262363044079 2.8918424954873387 0.0038298989573208 0.9999999827235042 0.0263121966713874 4 O75306,P00846,P03886 3 +Segmental peripheral demyelination remyelination 0.9230136994607528 2.889179112907827 0.0038624899746066 0.9999999851655548 0.0264970225356671 5 P03886,P00846,Q9NR77 3 +Abnormal cardiac exercise stress test 0.7342408996744633 2.884149358802852 0.0039247255972927 0.9999999889113156 0.0268448925582812 2 P0DP25 1 +Vitritis 0.7995855535819957 2.8830847487612807 0.0039380147642564 0.9999999895794488 0.0268962943869599 3 P53701,P04439 2 +Weakness due to upper motor neuron dysfunction 0.4012303032867038 2.874570497401346 0.0040457743930166 0.9999999937045708 0.0275514870214498 140 Q96CU9,P01889,Q6DKK2,Q9H9S5,P00846,Q9H9P8,O75306,Q5XKP0,P17900,Q13510,P35637,P51572,P00403,P31749,Q15041,Q9UBX3,P07602,Q9NZ08,Q9Y5Y5,O60313,P04062,O75298,O95831,P48637,Q9Y619,Q9NZJ7,Q9H0B6,O75489,P03886,Q13501,P22413,Q13423,Q9H6K4,Q7RTS9 34 +Anterior uveitis 0.7974517681369366 2.872581728377948 0.0040713275571599 0.999999994413728 0.0276850273886879 3 P14174 1 +Abnormal tissue metabolite concentration 0.7401627020054814 2.8703586811053388 0.0041000642197555 0.999999995116278 0.0278343476510799 16 Q9Y5Y5,Q9NZJ7,P07602,O43681,P06865,P40855,P17900,O75381,P06280 9 +Anal fissure 0.7315773897602875 2.869959973295245 0.0041052376205006 0.9999999952330312 0.0278343476510799 2 P78536 1 +Abnormal brain choline level by mrs 0.7955187126506568 2.863054925187486 0.0041957782359314 0.9999999968788088 0.0282426806690297 3 P07602 1 +Reduced brain n acetyl aspartate level by mrs 0.7955187126506568 2.863054925187486 0.0041957782359314 0.9999999968788088 0.0282426806690297 3 P07602 1 +Abnormal brain n acetyl aspartate level by mrs 0.7955187126506568 2.863054925187486 0.0041957782359314 0.9999999968788088 0.0282426806690297 3 P07602 1 +Mixed demyelinating and axonal polyneuropathy 0.8615748497096645 2.861423968790102 0.0042174264722365 0.9999999971793953 0.0283065886277779 4 P03886,P00403 2 +Retrocollis 0.7942569567791565 2.8568304574167356 0.0042789433000547 0.999999997884728 0.0286451963635011 3 P35637,Q99720 2 +Horizontal nystagmus 0.6419493683533646 2.856683802432234 0.0042809206564289 0.9999999979042042 0.0286451963635011 24 P04062,Q9NZJ7,P07602,P00846,O95831,O14773,Q9H061 7 +Malrotation of small bowel 0.8604532439167636 2.856283290309291 0.0042863250032976 0.9999999979565256 0.0286451963635011 4 Q8NCH0 1 +Oromandibular dystonia 0.860090612533253 2.854620536318256 0.0043088277458778 0.9999999981607068 0.0287543261322333 4 P35637,O60220 2 +Abnormality of femur morphology 0.4631776441275761 2.8453979104458043 0.0044355975252778 0.9999999989835718 0.0291259650563481 69 Q96HY6,P16278,O75718,P16435,Q14739,P07602,Q9Y487,Q32P28,P04062,Q7LGA3,O95831,O75844,Q96A33,Q9Y619,Q9NZJ7,P04066,Q9UHX1,P22413,Q7RTS9,P06280 20 +Peripheral hypermyelination 0.7910182527001337 2.8408313411855546 0.0044996102512746 0.999999999246642 0.0293135448257865 3 Q9NR77 1 +Heparan sulfate excretion in urine 0.8567014284124017 2.8390637744795297 0.0045246112966466 0.9999999993298124 0.0293941972381867 4 P15586,P54802 2 +Abnormal retinal artery morphology 0.6281941108004832 2.8377033829900244 0.0045439387457475 0.9999999993877624 0.0294786443978998 26 P10619,P17900,Q9NZJ7,P03886,P16278,P07602,P00846,P22413,P06865,Q13510 10 +Impaired vibratory sensation 0.601455113356693 2.8360913749166445 0.0045669377741683 0.9999999994502295 0.0295455502112171 30 Q9NR77,Q9Y619,O75298,Q9H0B6,P00846,O14773 6 +Incoordination 0.4523670019120823 2.8338845227215086 0.0045985946120943 0.9999999995259256 0.0295846306092417 74 P31483,Q9NR77,Q15067,P04062,Q9Y619,Q13501,Q9NZJ7,Q01105,Q6DKK2,Q9H9S5,P00846,P07602,O43681,Q10713,O75503,O14773,Q13510,Q7RTS9 18 +Inability to walk 0.4489977237857462 2.8308343258429085 0.0046426762284685 0.9999999996142926 0.029705475099185 88 P07196,P61978,Q96CU9,O15269,Q9H9S5,P00846,Q13510,P35637,Q99720,Q9NR77,Q15041,Q96JX3,Q96D71,Q71SY5,O75503,O60220,O14949,Q96N66,O43292,Q9NVI7,Q7RTS9 21 +Abnormal sternal ossification 0.854027565196301 2.8267693192921626 0.0047020186383934 0.9999999997078216 0.0300027435858038 4 Q9Y619 1 +Decerebrate rigidity 0.8537163162570284 2.8253369812811973 0.0047230914656186 0.9999999997352615 0.0300959781762677 4 P07602,P16278,Q9NZJ7 3 +Mitochondrial inheritance 0.9064116703957956 2.8171462461959793 0.004845245754218 0.9999999998505424 0.0307402126309438 5 P00846,P00403 2 +Abnormality of dental color 0.7852524184452757 2.8122696139572465 0.0049193249909271 0.9999999998943366 0.0310912019100933 3 P16278 1 +Abnormal choroid morphology 0.5903285928102185 2.809283922384128 0.0049651836882698 0.99999999991475 0.0311303572091403 31 Q9Y5Y5,P31749,Q9Y619,P04439,P53701,Q9H9S5,O43505,Q8IY17,P22413,Q10713,P40855,Q5XKP0,O75381 13 +Postural tremor 0.7111682009585419 2.8073605567409374 0.0049949299859888 0.9999999999258318 0.0311303572091403 17 Q14108,Q9NR77,P03886,P00846,O14773,P35637 6 +Abnormal circulating arginine concentration 0.7197395679195064 2.80659133682941 0.0050068715935251 0.9999999999298642 0.031137527213138 2 Q9NVS9 1 +Central diabetes insipidus 0.714412548091155 2.777912048588029 0.0054709424616721 0.9999999999920164 0.0335311184032483 2 O76024 1 +Retinal perforation 0.714412548091155 2.777912048588029 0.0054709424616721 0.9999999999920164 0.0335311184032483 2 P04439 1 +Dysgerminoma 0.7144125480911552 2.777912048588029 0.0054709424616721 0.9999999999920164 0.0335311184032483 2 P31749 1 +Ovarian papillary adenocarcinoma 0.7144125480911552 2.777912048588029 0.0054709424616721 0.9999999999920164 0.0335311184032483 2 P31749 1 +Severely reduced visual acuity 0.7144125480911548 2.777912048588029 0.0054709424616721 0.9999999999920164 0.0335311184032483 2 Q13277 1 +Peripheral axonal degeneration 0.4603519049402595 2.772769710241213 0.0055581438908209 0.9999999999946934 0.0339316307253527 68 P07196,P22626,Q15067,Q9NZJ7,Q9BQT8,Q9H0B6,P03886,Q9BPX6,Q6DKK2,O15269,Q8IV08,P07602,P00846,O95831,Q9NVI7,Q96BR5,P00403 17 +Functional motor deficit 0.3925031180481474 2.767065976237219 0.0056563306715595 0.9999999999966498 0.0343509625399276 151 P07196,Q15907,P61978,Q9BPX6,Q9Y2R0,Q9H9S5,P00846,Q13510,P35637,Q99720,P00403,Q9NWM8,P31749,Q9H2D1,Q9NR77,Q15041,Q9GZY8,P07602,Q15067,P04062,O75298,Q8NI60,Q71SY5,Q9NSD9,O14773,P31483,Q9NZJ7,Q9H0B6,Q13501,P03886,P53701,O43681,O43292,Q05639,Q7RTS9 35 +Increased cerebral lipofuscin 0.8948459715639775 2.7665857654249573 0.0056646682365923 0.999999999996778 0.0343568029245408 5 O14773,P07602,P50897,O75503 4 +Bilateral tonic clonic seizure with focal onset 0.7757557655392177 2.7650060062747865 0.0056921747705669 0.9999999999971676 0.0344511016294831 3 P07602 1 +Amyloidosis 0.7730622352593965 2.751550356772744 0.0059313899713033 0.9999999999990764 0.0353756907635482 3 P05067 1 +Abnormality of head blood vessel 0.596422741422244 2.7426123670064984 0.0060952591499212 0.9999999999995716 0.0358481276771884 29 P10619,P17900,Q9NZJ7,P03886,P16278,P07602,P00846,Q9Y4P3,P22413,P06865,Q13510 11 +Abnormal visual electrophysiology 0.5247563194216408 2.738245451094479 0.0061767956533849 0.9999999999997076 0.0362361639212429 48 O60313,Q15555,P50897,Q15067,Q9NZJ7,Q9GZY8,Q9H936,Q04837,P07602,P00846,O43681,Q96S66,O75503,O14773,O60220 15 +Erlenmeyer flask deformity of the femurs 0.8347645839502463 2.7376438445486273 0.0061881051406151 0.9999999999997228 0.0362568474779692 4 P07602,Q9NZJ7,P04062 3 +Synostosis of metacarpals metatarsals 0.7687118200185423 2.729770494695387 0.0063378430988692 0.9999999999998626 0.0369482767891523 3 P16435 1 +Abnormal delivery 0.623047366510384 2.7253706232608272 0.0064229343194754 0.9999999999999076 0.0373508465169998 24 O75718,Q9Y619,Q969X5,P22413,O75844,P33991,Q9Y487 7 +Thickened ribs 0.8315388361010999 2.7226232559769445 0.0064765868901601 0.9999999999999284 0.0376158874493342 4 P15586,P54802 2 +Bilateral sensorineural hearing impairment 0.6173144225531987 2.7215188552302942 0.0064982677906961 0.9999999999999352 0.037694808678783 25 Q15067,Q9NZJ7,Q13501,P03886,P07602,P35637,P38159,P00403 8 +Sensory ataxia 0.8839367013680954 2.718606512729257 0.0065557544797236 0.9999999999999504 0.0378867299833162 5 Q9NR77 1 +Abnormality of visual evoked potentials 0.6360868843880342 2.7157464248321004 0.0066126544306286 0.999999999999962 0.0381682085971105 21 O60313,Q15067,Q9NZJ7,Q9GZY8,Q9H936,P07602,O43681,O75503,O60220 9 +Symphalangism affecting the phalanges of the hand 0.7655547004092715 2.7139281420984456 0.0066490587185874 0.999999999999968 0.038283455514438 3 P48651 1 +Peripheral axonal neuropathy 0.5045980127143176 2.709336165283622 0.0067417992537475 0.9999999999999792 0.0387695073135258 52 P07196,P22626,Q15067,Q9NZJ7,Q9H0B6,P03886,Q9BPX6,O15269,Q8IV08,P07602,P00846,O95831,Q9NVI7,Q96BR5,P00403 15 +Metatarsus valgus 0.8263032837898443 2.6981851586986254 0.0069718650944261 0.999999999999993 0.0397551259989169 4 O43505,Q9H9S5 2 +Ambiguous genitalia male 0.761798499877451 2.695039402947189 0.007038030766491 0.9999999999999948 0.0397551259989169 3 Q15392 1 +Central y shaped metacarpal 0.6990233796981395 2.6944850130470455 0.0070497496940973 0.9999999999999952 0.0397551259989169 2 O43924 1 +Partial duplication of the distal phalanges of the hand 0.6990233796981398 2.6944850130470455 0.0070497496940973 0.9999999999999952 0.0397551259989169 2 Q8WVQ1 1 +Hypoplasia of olfactory tract 0.6990233796981395 2.6944850130470455 0.0070497496940973 0.9999999999999952 0.0397551259989169 2 O43924 1 +Hypothalamic hamartoma 0.6990233796981395 2.6944850130470455 0.0070497496940973 0.9999999999999952 0.0397551259989169 2 O43924 1 +Lobulated tongue 0.6990233796981395 2.6944850130470455 0.0070497496940973 0.9999999999999952 0.0397551259989169 2 O43924 1 +Duplication of the distal phalanx of the thumb 0.6990233796981398 2.6944850130470455 0.0070497496940973 0.9999999999999952 0.0397551259989169 2 Q8WVQ1 1 +Neoplasm of the gallbladder 0.823764361861006 2.6863078531185143 0.0072246488780449 0.999999999999998 0.0403022927831538 4 P07602,Q9NZJ7 2 +Biliary tract neoplasm 0.823764361861006 2.6863078531185143 0.0072246488780449 0.999999999999998 0.0403022927831538 4 P07602,Q9NZJ7 2 +Abnormal response to endocrine stimulation test 0.7588192517055841 2.680026553665833 0.0073616320211691 0.9999999999999988 0.0410173229122079 3 Q13423 1 +Splenomegaly 0.4283782401052217 2.672355657340725 0.0075320770932978 0.9999999999999994 0.0416679514258685 91 P00813,Q14108,P01889,P15586,Q96HY6,Q13510,P16278,O15118,P31749,P36551,Q14739,P07602,P61916,Q9NZ08,P14174,P54802,P04062,Q16625,P33991,Q15392,Q96A33,Q9NZJ7,P04066,P10253,Q10713 25 +Bulbar signs 0.7708402147011694 2.671151397611674 0.0075591543973159 0.9999999999999996 0.0417681390067586 12 Q9NZJ7,P04062,P03886,P07602,P00846,P35637,Q99720 7 +Central scotoma 0.7849428867702688 2.6657965646716466 0.0076806154978781 0.9999999999999998 0.0422388512268197 11 O60313,P03886,P00846,Q9H6K4,O75306,O60220,Q9Y287,Q9H061 8 +Abnormal chorioretinal morphology 0.5790081009560485 2.664735316483468 0.0077048939374759 0.9999999999999998 0.0423106230491026 30 Q9Y5Y5,P31749,Q9Y619,P04439,P53701,Q9H9S5,O43505,Q8IY17,Q10713,P40855,Q5XKP0,O75381 12 +Barrel shaped chest 0.8716953639595997 2.664432542011269 0.0077118331834882 0.9999999999999998 0.0423106230491026 5 Q7RTS9,Q32P28,P04066 3 +High frequency sensorineural hearing impairment 0.8705621567359004 2.659399453442233 0.0078280091257558 1.0 0.0426965649973897 5 Q13510,O75844 2 +Cloverleaf skull 0.6919206865936709 2.6556892772828204 0.0079146503501386 1.0 0.0429678803390974 2 P16435 1 +Abnormality of the proximal phalanx of the thumb 0.6919206865936709 2.6556892772828204 0.0079146503501386 1.0 0.0429678803390974 2 Q15233 1 +Loss of speech 0.6302369603127952 2.6470227407806504 0.0081203892077823 1.0 0.0440212990823483 20 O15118,P50897,Q9NZJ7,Q13501,P07602,P61916,P17900 7 +Abnormal pericardium morphology 0.7501945782120343 2.643844763890601 0.0081970240151449 1.0 0.0443458047184034 13 Q14108,P04062,P01889,P22413,Q9NZ08,P14174 6 +Elevated serum acid phosphatase 0.8104348493948311 2.623667640405365 0.0086988624488364 1.0 0.046254910144612 4 P07602,Q9NZJ7 2 +Scotoma 0.7298416068070871 2.619017324167642 0.0088183468988531 1.0 0.0468367843270902 14 O60313,P04439,P03886,P00846,Q9H6K4,O75306,O60220,Q9Y287,Q9H061 9 +Punctate cataract 0.8091957668154744 2.617820447163725 0.0088493355551977 1.0 0.0469478417039989 4 P08670,Q9H6K4 2 +Abnormal circulating citrulline concentration 0.8609501420541609 2.616584243673055 0.0088814445185185 1.0 0.0470111006446131 5 P00846,Q9Y619 2 +Status epilepticus with prominent motor symptoms 0.8088456093650546 2.6161673133159 0.0088922972498202 1.0 0.0470151198520573 4 Q13510 1 +Focal segmental glomerulosclerosis 0.6066171946444894 2.609584187606127 0.0090652337142227 1.0 0.0476589826646157 24 O95470,Q14108,P03886,Q8NFH4,P00403,Q14C86 6 +Somatic sensory dysfunction 0.3999867990842762 2.5983513541297816 0.009367259165947 1.0 0.0489155753306966 108 P07196,P61978,O15269,P00846,Q9NR77,Q8IV08,P05067,P07602,P54802,O75298,Q8NCH0,O95831,Q71SY5,O14773,Q8N2K0,Q9Y619,Q9NZJ7,Q9H0B6,Q9H6K4,Q96BR5,P06280 21 +Abnormal mitochondrial number 0.6803788102989092 2.592250560520604 0.0095350298639422 1.0 0.0495693851632177 2 P46976 1 +Brushfield spots 0.854078574091715 2.585839564920264 0.0097142134863397 1.0 0.0503036630569897 5 Q9Y5Y5,P40855 2 +Hashimoto thyroiditis 0.6783071914767728 2.5808120006788697 0.0098568243192458 1.0 0.0503036630569897 2 Q96J02 1 +Stuttering 0.8012329364943676 2.580144992445005 0.0098758840258934 1.0 0.0503036630569897 4 P00403 1 +Gait ataxia 0.4369082793085104 2.579517888219466 0.0098938334201015 1.0 0.0503036630569897 70 P07196,Q15907,Q05086,Q14108,Q9P0J1,P00846,O15118,Q9NR77,Q8IV08,P07602,O14773,Q9NZJ7,Q13501,P03886,O43681,Q10713,O43292,Q9NVI7,Q96BR5 19 +Ascites 0.5816225874196093 2.5791866970735953 0.0099033247167561 1.0 0.0503036630569897 28 O15118,Q14108,P04062,Q14739,P61916,P22413,Q01844,Q9NSD9,Q13510 9 +Insidious onset 0.8010041685094522 2.57906005679321 0.009906956125236 1.0 0.0503036630569897 4 Q9NR77,P04062 2 +Saccadic smooth pursuit 0.8004045428779176 2.5762156488244847 0.0099888326510368 1.0 0.0503036630569897 4 O14773 1 +Aplasia hypoplasia of the sternum 0.8003732766095617 2.576067306130672 0.0099931191970881 1.0 0.0503036630569897 4 P98175 1 +Abnormal pyramidal sign 0.3935041619677173 2.5753527880689697 0.0100137890430145 1.0 0.0503036630569897 122 P07196,P51648,P01889,Q6DKK2,Q9H9S5,P00846,Q9H9P8,O75306,P17900,P35637,P51572,Q99720,Q9NR77,P07602,Q9NZ08,O60313,Q15067,O75298,Q8NI60,O95831,O14773,O60220,Q8N2K0,Q9Y619,Q9NZJ7,Q13501,P04066,Q9H6K4 28 +Vascular skin abnormality 0.3895474632577104 2.570464265803836 0.0101562304079327 1.0 0.0504884965209721 129 P10619,O60762,P51648,Q14108,Q15125,P07858,P01889,Q9Y2B2,P48651,P00846,O75306,P16278,P00403,Q9NWM8,P31749,Q9NX14,Q14739,P22830,P51798,P49257,Q8IZA0,Q9Y487,Q08J23,P04062,P38435,P98194,Q13126,Q8NCH0,Q86YV9,Q16625,O75844,P03886,P04066,P53701,P22413,P78536,P06280 37 +Cardiorespiratory arrest 0.7353463587921756 2.5607719822100856 0.0104439877781832 1.0 0.0518041451959137 3 O43772,P13473 2 +Abnormality of pulmonary circulation 0.5449381033966262 2.560430737438883 0.0104542499965991 1.0 0.0518041451959137 33 P31749,Q14108,P04062,P03886,P01889,P20674,P22413,Q71SY5,O75844,Q8IZA0,Q9NZ08,P00403 12 +Generalized osteosclerosis 0.7348744192074397 2.558356493066994 0.0105168217536959 1.0 0.0519484154069095 3 Q15392 1 +Abnormality of the vasculature of the eye 0.4285584121804534 2.5543252237411447 0.0106393828532553 1.0 0.0524981412398978 73 P10619,P01889,P00846,O75306,Q13510,P16278,P17900,Q14739,Q96DF8,P07602,Q9NZ08,P38435,Q9Y4P3,Q9NZJ7,P03886,P04066,P22413,P06865,Q96S66,P06280 20 +Ectopic calcification 0.4624112578414957 2.553717052296846 0.0106579827042327 1.0 0.0525342681865781 61 Q15125,P40855,P00403,P53634,Q14739,P05067,Q9Y5Y5,O60313,P04062,P38435,Q16625,O75844,Q9NSD9,P08236,O00584,P03886,O75845,P22413,O75381 19 +Elevated circulating long chain fatty acid concentration 0.7334931540481422 2.551282827141589 0.0107327189962738 1.0 0.0527006928286398 3 P40855 1 +Slow pupillary light response 0.7951280578976965 2.551143767940952 0.010737002467664 1.0 0.0527006928286398 4 P07602,Q9NR77 2 +Abnormal pupillary light reflex 0.7951280578976965 2.551143767940952 0.010737002467664 1.0 0.0527006928286398 4 P07602,Q9NR77 2 +Macular degeneration 0.7327886477279021 2.5491489704427397 0.0107986161601936 1.0 0.0528360862123759 13 Q13510,P50897,P04062 3 +Gastric ulcer 0.7312018946121706 2.5395356156972424 0.0110999743035611 1.0 0.0540785047964111 3 P04062,O76024 2 +Limb ataxia 0.5963210573590062 2.5362311649320533 0.0112052740095347 1.0 0.054312347904696 24 Q9NR77,Q14108,O75298,P04062,Q8IV08,Q10713,O14773 7 +Subcutaneous nodule 0.608949205318433 2.530912844019946 0.0113766113556288 1.0 0.0549242626324948 21 P31749,P01889,P22413,O75874,P48735,Q13510,P35637,P06280 8 +Global brain atrophy 0.5953278637849075 2.529122641781834 0.0114348062923779 1.0 0.0550240988738598 24 Q9NZJ7,Q13501,O60220,Q9UHX1,P07602,Q9H9P8,O75306,P35637 8 +Polar cataract 0.8408191117035839 2.526191057035324 0.0115306754603032 1.0 0.0553710167980337 5 P08670,Q9Y287 2 +Cerebellar cortical atrophy 0.7268020459631523 2.516931035721628 0.0118381998393088 1.0 0.0567307971723259 3 O75845 1 +Abnormal retinal morphology 0.3680989807993897 2.515036045873164 0.0119020214345568 1.0 0.0569780224482692 224 P10619,P51648,P50897,Q96CU9,P01889,Q9H9S5,P00846,P40855,O75306,Q5XKP0,P17900,Q13510,P16278,P00403,P31749,Q96DF8,P07602,O43505,Q9NZ08,Q9Y287,Q9Y487,Q9Y5Y5,O60313,Q9UG56,Q15067,P04062,P38435,Q8N3R9,Q8NCH0,Q86YV9,Q7LGA3,Q9Y4P3,O75503,O14773,Q8N2K0,P48637,Q15555,Q9Y619,Q9NZJ7,O75489,O95202,P03886,Q9UHX1,Q10713,P22413,P06865,Q96S66,Q05639,O75381 49 +Amyotrophic lateral sclerosis 0.6623455462365503 2.511338082245709 0.0120274447629948 1.0 0.0574128108125816 17 P22626,P31483,Q92804,Q13501,Q68CQ7,P35637,Q15165,Q99720 8 +Ventricular septal hypertrophy 0.725701712697779 2.5112683702382688 0.0120298203849462 1.0 0.0574128108125816 3 P06280 1 +Abnormal nervous system electrophysiology 0.3719794602944994 2.507312096412219 0.0121653244001422 1.0 0.0579431867854243 201 P07196,P50897,Q14108,Q15125,O15269,Q9H9S5,P40855,Q99720,P00403,O95721,Q9NR77,Q9UBX3,Q9GZY8,P07602,Q2M389,Q9BQE5,Q9Y5Y5,O60313,P13073,Q08J23,Q15067,Q3ZCQ8,O95831,Q71SY5,O75503,O14773,O60220,Q96A33,Q9NQZ5,Q8N2K0,Q9Y619,Q9NZJ7,O95202,P03886,Q96N66,Q13501,Q9H936,O43681,O43292,Q05639,O75381 41 +Epiphyseal stippling 0.6942873258231996 2.5072974044902145 0.0121658301151019 1.0 0.0579431867854243 15 Q9Y5Y5,Q14739,Q15125,P38435,P40855,P08236,O75381 7 +Angina pectoris 0.8362339290061241 2.5054648311332817 0.012229055930967 1.0 0.0581848238268073 5 O75844,P06280 2 +Fever 0.4313762278688792 2.5048278968543296 0.012251098952356 1.0 0.0582302233878313 83 P00813,P61978,P01889,P00846,Q13510,P51572,P00403,Q9NR77,Q14739,P07602,P14174,Q14C86,Q8NFH4,Q9NZJ7,P03886,P10253,Q9HC07,P22413,Q8N1F7,P06280 20 +Pain 0.374243102068734 2.502487897833227 0.0123323841724911 1.0 0.0583782982474226 182 Q14108,P01889,P42892,O15269,Q9H9S5,P00846,Q68CQ7,Q96HY6,O75874,Q13510,P35637,P31749,Q70HW3,P22626,Q9NR77,P36551,Q14739,P07602,P48735,Q15800,P50402,Q9NZ08,P14174,Q14C86,O60313,Q92804,P04062,Q9Y4P3,O75844,Q8NFH4,Q15165,O15460,Q9NZJ7,P22413,Q8N1F7,Q01844,Q13423,Q9H6K4,P06280 39 +Upper motor neuron dysfunction 0.3278149556483662 2.4986798530717405 0.0124656869565462 1.0 0.0585334373423311 388 P50897,P00846,Q9H9P8,Q13510,P00403,Q9NR77,Q9UBX3,P07602,Q2M389,Q9Y487,Q9Y5Y5,P04062,Q96JX3,O95831,O75503,O14773,Q9Y619,P03886,Q13423,Q7RTS9,P51648,Q6DKK2,Q68CQ7,Q86XL3,P17900,P35637,Q15041,Q9Y287,Q15067,Q92804,O75298,Q8NI60,Q96D71,O43464,O60220,Q8N2K0,O00584,Q9H0B6,P04066,Q10713,O43292,Q9H6K4,Q05639,P07196,Q96CU9,Q9H9S5,P40855,Q5XKP0,O15118,P11117,O43505,P61916,Q3ZCQ8,Q71SY5,Q15392,Q15165,P48637,Q9NZJ7,Q96N66,P22413,Q9NVI7,O75381,P01889,Q01105,O75306,P16278,P51572,Q99720,P31749,P22626,Q9GZY8,Q9NZ08,O60313,Q08J23,Q9Y4P3,Q16625,O75489,Q13501,Q9H936,O43681,Q9UNW9 81 +Elevated pulmonary artery pressure 0.5707190321423077 2.4966597891367095 0.0125369171441165 1.0 0.0586904121178842 28 Q14108,P04062,P03886,P01889,P20674,P22413,Q71SY5,O75844,Q8IZA0,P00403 10 +Sensory neuropathy 0.5317957596320715 2.489366136633596 0.0127971100025101 1.0 0.0594306464523353 35 P22626,Q15067,Q9H0B6,Q15041,P03886,O15269,Q8IV08,P00846,O95831,O60220,P00403 11 +Increased bone mineral density 0.5796454872203539 2.4857761662859965 0.0129269243765737 1.0 0.059740567143088 26 Q14108,P04062,Q14739,Q15125,Q13501,P48651,P51798,Q9Y4P3,P22413,Q15392,P54802 11 +Scanning speech 0.7207091279685192 2.4855265307113084 0.0129359944422104 1.0 0.059740567143088 3 O14773 1 +Abnormal circulating porphyrin concentration 0.779780034975909 2.4777838936693715 0.0132201190348062 1.0 0.0606692753341157 4 P22830 1 +Abnormality of corneal stroma 0.7045682169710729 2.476900398751672 0.013252888013588 1.0 0.0607597956370995 14 P10619,Q13510,P04062,O75845,O43505,P16278 6 +Abnormal nephron morphology 0.4401757072670202 2.4669004975360096 0.0136288223610523 1.0 0.0621773306148695 66 P00813,O95470,P06280,Q14108,Q14C86,P03886,P01889,P00846,Q8N1F7,O75306,Q8NFH4,Q9NZ08,P00403 13 +Abnormality of the optic nerve 0.357916799067239 2.4619484573371464 0.0138184523526352 1.0 0.0626780002124485 266 P07196,Q15907,Q13277,P50897,Q96PU5,P61978,Q15125,Q96CU9,Q9BPX6,P01889,Q9H9S5,P00846,Q9H9P8,O43676,P40855,O75306,Q5XKP0,P16278,P51572,Q9H061,P00403,P31749,O95721,P78318,P04439,Q9GZY8,Q6P4Q7,Q04837,P07602,P51798,O43505,Q86Y39,Q9NZ08,Q9Y287,O95298,Q9Y5Y5,Q9UG56,O60313,Q15067,Q9NPL8,P04062,P38435,Q8N3R9,Q96JX3,Q7LGA3,Q3ZCQ8,O95831,O60220,P98175,Q8N2K0,Q15555,O15460,Q9NZJ7,Q9H0B6,O95202,P03886,O75489,Q9UHX1,O43681,Q10713,O43292,Q96S66,Q9H6K4,Q05639,Q9NVI7,O75381,P06280 67 +Paresthesia 0.5904878038713531 2.461926418766877 0.0138193014637579 1.0 0.0626780002124485 23 P07196,Q9NR77,P01889,P05067,Q9H6K4,Q9NZ08,P54802,P06280 8 +Prominent ear helix 0.7763764082626189 2.461427971768917 0.0138385181437905 1.0 0.0627041026398603 4 O75844 1 +Fibrosarcoma 0.7146240378922424 2.454044244229487 0.0141259599957936 1.0 0.0634901894963917 3 P25054,Q13126 2 +Abnormal peripheral nervous system physiology 0.463152376192303 2.4511375012257273 0.0142405542779491 1.0 0.063628596854302 57 P07196,O60313,O95721,Q9NR77,Q9NQZ5,Q9Y619,Q9NZJ7,Q15125,Q9GZY8,O15269,P07602,O95831,Q71SY5,O60220,Q99720,Q8N2K0 16 +Paraparesis 0.5699119504532565 2.4508618258956063 0.0142514648564249 1.0 0.063628596854302 27 Q9Y5Y5,Q9Y619,P04062,Q6DKK2,Q9H6K4,Q13510,P35637 7 +Short nail 0.7737032980044529 2.4485601905581222 0.0143428463430761 1.0 0.0637365126464711 4 Q9Y487 1 +Impaired vibration sensation in the lower limbs 0.7144605034180296 2.448287316462288 0.0143537144195251 1.0 0.0637365126464711 13 P00846,Q9NR77,O75298 3 +Broad femoral neck 0.7716594684357979 2.43870837679888 0.0147398578840738 1.0 0.0647683614475731 4 Q7RTS9 1 +Platyspondyly 0.5300275429537923 2.437210299802418 0.0148010686938526 1.0 0.0649184350056174 33 P00813,Q32P28,Q14739,Q8WVQ1,P04066,Q96HY6,O95831,O75874,P48735,P16278,Q7RTS9 11 +Abnormality of lysosomal metabolism 0.8203224713876718 2.4331422527902693 0.0149684188920873 1.0 0.0654675072294298 5 P07602,Q13510,Q9NZJ7 3 +Pancreatic islet cell hyperplasia 0.7100567191282393 2.430336675525402 0.0150848030520593 1.0 0.065791210315068 3 P53985 1 +Delusions 0.594258643294413 2.429189656910488 0.0151326140521497 1.0 0.0659379946257375 21 P04062,P36551,Q9NZJ7,Q96DF8,P07602,Q9BQE5,O60220 7 +Corneal opacity 0.4561278920786557 2.42843841399668 0.0151640002741375 1.0 0.0660130030625539 59 P10619,P51648,Q9H9S5,P40855,P16278,Q13510,O43505,Q9Y5Y5,P04062,Q9Y4P3,Q16625,O75844,P08236,O95202,P04066,O75845,Q9NVI7,O75381,P06280 19 +Arthritis 0.5087661191374101 2.4278698477676777 0.0151877925331418 1.0 0.0660548437155692 43 Q14108,P04062,Q14739,Q8WVQ1,P01889,P10321,Q96HY6,O75844,Q13510,Q9NZ08,P14174,P06280 12 +Abnormality of fontanelles 0.467209614792286 2.4221704994341904 0.0154281100297821 1.0 0.067005998088642 54 Q9Y5Y5,O75718,Q08J23,Q32P28,P16435,Q9Y619,Q15125,P20674,Q8NCH0,P48651,P40855,O75844,O75381,P98175,Q9Y487 15 +Tongue nodules 0.7072778392868335 2.415879679484109 0.0156972474633618 1.0 0.0678259258046676 3 P98175 1 +Vitreous hemorrhage 0.64871263687482 2.4156560323659857 0.0157068912220179 1.0 0.0678259258046676 2 P35222 1 +Cherry red spot of the macula 0.7629758896488428 2.4088441356846646 0.0160031308275168 1.0 0.0686867697463878 10 P10619,Q9NZJ7,P17900,P07602,P06865,Q13510 6 +Abnormal social behavior 0.4186669380307011 2.408201300954093 0.0160313388253892 1.0 0.0686867697463878 76 Q15907,Q15125,Q96CU9,O96008,O43676,O75306,Q5XKP0,Q8N183,Q9NX14,Q9GZY8,P05067,P07602,Q86Y39,Q8TAB3,O95298,Q15067,Q9NPL8,Q9Y4P3,O43464,O75489,Q9NZJ7,P03886,Q9UHX1,O43681 24 +Neurofibrillary tangles 0.813531752066689 2.402087223822244 0.0163018208805172 1.0 0.0694729017945556 5 O15118,Q9Y287,P05067 3 +Corpus callosum atrophy 0.660331522421401 2.3996422252380274 0.0164111031260603 1.0 0.0697471882857563 16 Q9Y5Y5,Q9H9P8,P51572,O75503 4 +Shallow acetabular fossae 0.6457531814146247 2.3989596919004317 0.0164417244787813 1.0 0.0698136304668764 2 Q9ULC3 1 +Abnormal intraocular pressure 0.7628164992058809 2.3959502998286606 0.0165773379313305 1.0 0.0700600313202217 4 Q8NCH0 1 +Motor neuron atrophy 0.5754792009968824 2.385843056975203 0.0170400212389205 1.0 0.0715711622460703 24 P22626,P31483,Q92804,Q13501,Q68CQ7,Q13510,P35637,Q15165,Q99720 9 +Joint swelling 0.8581933847126193 2.3774356729072914 0.0174334834497529 1.0 0.0730919585139056 6 Q13510 1 +Abnormal peripheral myelination 0.5353497801049677 2.374690848970162 0.0175636538037713 1.0 0.0735714922823443 31 P07196,Q9NR77,Q9H0B6,P03886,O15269,P07602,P00846 7 +Tetraplegia tetraparesis 0.4861283308213197 2.372658404367487 0.0176605885869147 1.0 0.0737123849801514 48 P48637,O75489,Q9NZJ7,Q13501,Q9UBX3,P07602,P00846,Q9H9P8,P51572,O95831,Q13423,P17900,P35637,Q7RTS9 14 +Abnormal csf protein level 0.7138832294116799 2.366619418961136 0.0179513818772505 1.0 0.0748493734347197 12 Q9NR77,Q9NZJ7,P03886,P07602,Q16625,P00403 6 +Abnormal retinal vascular morphology 0.4657019470712724 2.362667344614956 0.0181439477603289 1.0 0.0754593827389393 53 P10619,P17900,P38435,Q9NZJ7,Q96DF8,P03886,P16278,P07602,P00846,Q9Y4P3,P22413,P06865,Q96S66,O75306,Q13510 15 +Arteriosclerosis 0.6377574746659446 2.358311966883445 0.0183582576765759 1.0 0.0762145848997244 17 O15118,P38435,O75845,P61916,P22413,O75844,Q13510 7 +Abnormality of epiphysis morphology 0.4332597690584865 2.353133599141145 0.0186159442444548 1.0 0.0772155550228592 65 Q15125,Q96HY6,P40855,P16278,P16435,Q14739,Q8WVQ1,P51798,Q9Y5Y5,Q9UG56,P38435,Q7LGA3,O95831,P08236,Q9Y619,O95202,Q9HC07,O75381,Q7RTS9 19 +Skin nodule 0.566224189608867 2.351033028668819 0.0187213719816943 1.0 0.0775186539067171 25 P31749,P01889,P22413,O75874,P48735,Q13510,P35637,Q9NZ08,P06280 9 +Abnormality of the spleen 0.3796162640996133 2.35043016248106 0.0187517261685357 1.0 0.0775186539067171 120 P10619,P00813,Q14108,P01889,P15586,Q96HY6,Q13510,P16278,O15118,P31749,P36551,Q14739,P07602,P61916,Q9NZ08,P14174,P54802,P04062,Q16625,P33991,Q15392,Q96A33,Q9NZJ7,O95202,P04066,O75845,P10253,Q10713 28 +Episodic hypertension 0.6371707605800586 2.3503535490082275 0.0187555867223851 1.0 0.0775186539067171 2 P21912 1 +Difficulty walking 0.416257808940665 2.348238024827776 0.0188624630172731 1.0 0.0778912701546615 80 Q9BPX6,Q9H9S5,P00846,Q13510,P35637,Q99720,P31749,Q9NR77,Q15041,P07602,Q15067,O75298,Q71SY5,O14773,P31483,Q9NZJ7,Q9H0B6,Q13501,O43681,O43292,Q05639,Q7RTS9 22 +Nemaline bodies 0.7529310711752439 2.34789626433856 0.0188797786406507 1.0 0.0778937191391948 4 O43676 1 +Peripheral demyelination 0.651743462045551 2.3474370776934417 0.0189030656589215 1.0 0.077920778618811 16 P07196,Q9NR77,Q9NZJ7,P03886,P07602,P00846 6 +Osteoarthritis 0.7102339548759843 2.346735890125581 0.0189386738850194 1.0 0.0779395425203832 12 Q14108,P04062,Q8WVQ1,P01889,Q96HY6,O75844 6 +Visual field defect 0.479777940291247 2.346359447262276 0.0189578148723903 1.0 0.0779395425203832 49 Q9Y5Y5,P31749,O60313,Q15555,O15460,P04439,P03886,P01889,P00846,O75381,P40855,Q9H6K4,O75306,O60220,Q9Y287,Q9H061,P00403 17 +Absent brainstem auditory responses 0.7522798206886667 2.3447209932486417 0.0190413225095003 1.0 0.0780705435572367 4 P07196,O60220 2 +Mucosal telangiectasiae 0.7502730649890855 2.344363966238455 0.019059561842013 1.0 0.0780705435572367 10 P10619,P31749,P06280,Q8IZA0 4 +Sinus bradycardia 0.6934864417425186 2.3437640808548985 0.0190902424026819 1.0 0.0780705435572367 3 P0DP25 1 +Extramedullary hematopoiesis 0.7517654709688137 2.342212374154957 0.0191698033118639 1.0 0.0782668426848112 4 P98175 1 +Abnormality of the distal phalanges of the toes 0.8261080182669922 2.341808504912756 0.0191905584408471 1.0 0.078274624533683 7 O75844,Q7LGA3,Q71SY5 3 +Decreased calvarial ossification 0.7514312124041328 2.3405817150254045 0.0192537245459731 1.0 0.0784524336568706 4 O75844 1 +Mild short stature 0.7513751343188191 2.340308111401263 0.0192678368620566 1.0 0.0784524336568706 4 Q14739 1 +Duplication of phalanx of hallux 0.6921255180580267 2.3366146628051276 0.0194592293513169 1.0 0.0790934470492446 3 Q2M1P5,Q8WVQ1 2 +Episodic vomiting 0.6934981822855486 2.331469266144654 0.0197286288355367 1.0 0.0800714110051629 13 Q9Y619,P61978,P03886,P22695,P00846,P00403 6 +Head banging 0.6336194140278241 2.3301593427804685 0.0197977309421804 1.0 0.0802592086411456 2 P28482 1 +Retinal telangiectasia 0.7975598287291557 2.328597614262 0.0198803925748523 1.0 0.0803147169242515 5 P03886,P00846 2 +Abnormal renal cortex morphology 0.4511097349305842 2.322725889800971 0.0201938825345877 1.0 0.0811178659504952 57 P00813,O95470,P06280,Q14108,Q14C86,P03886,P01889,P00846,Q8N1F7,Q8NFH4,P00403 11 +Upper limb asymmetry 0.7476405704190696 2.322067695368929 0.0202292908139349 1.0 0.0811178659504952 4 P31749 1 +Delayed ossification of carpal bones 0.6321396862977267 2.3217310333730508 0.0202474228402866 1.0 0.0811178659504952 2 Q9NUQ7 1 +Erythema 0.5620698531920694 2.320213479065505 0.0203293317908228 1.0 0.0812492491876904 25 P51648,P07858,Q15125,P22830,P01889,P98194,Q9Y2B2,P03886,P53701,P78536,P00403 11 +Irregular capital femoral epiphysis 0.631843740751707 2.320044379142701 0.0203384767180865 1.0 0.0812492491876904 2 Q9NUQ7 1 +Abnormal arterial physiology 0.5476163592075016 2.31922329608186 0.0203829319418382 1.0 0.0812874118022967 28 Q9NWM8,Q14739,P01889,P05067,Q9Y4P3,P22413,O75844,Q9NZ08,P06280 9 +Optic atrophy 0.3621018259063464 2.317049983898417 0.0205010091128055 1.0 0.0816883665076544 195 Q15907,P50897,Q96PU5,Q15125,Q96CU9,Q9BPX6,P01889,Q9H9S5,P00846,Q9H9P8,P40855,O75306,Q5XKP0,P16278,P51572,Q9H061,P00403,O95721,Q9GZY8,Q6P4Q7,Q04837,P07602,O43505,Q86Y39,Q9Y5Y5,O60313,Q15067,Q96JX3,Q3ZCQ8,O60220,P98175,Q8N2K0,Q15555,O15460,Q9NZJ7,Q9H0B6,O95202,P03886,O75489,O43681,O43292,Q9H6K4,Q05639,Q9NVI7,O75381,P06280 46 +Respiratory failure 0.408402074139442 2.3137644173340663 0.0206806481956651 1.0 0.0823337258935114 72 Q9H9S5,Q68CQ7,O75306,Q5XKP0,Q13510,P35637,Q70HW3,P07602,P61916,Q92804,Q9NSD9,Q9BUB7,O43464,P33991,Q15165,Q9Y619,Q9NZJ7,Q13501,P53701,P10253 20 +Nocturnal hypoventilation 0.6865775539089374 2.3074076278196234 0.021032106402345 1.0 0.0835900611110268 3 Q9H9S5 1 +Abnormal larynx physiology 0.6450114689823915 2.3062976079508952 0.0210940087164028 1.0 0.0836603168464202 16 Q92804,Q13501,Q68CQ7,Q13510,P35637,Q15165 6 +Duplication of the distal phalanx of hand 0.6859088217880427 2.303880432658101 0.0212293564004006 1.0 0.0836603168464202 3 Q2M1P5,Q8WVQ1 2 +Connective tissue nevi 0.6859088217880366 2.3038804326580693 0.0212293564004024 1.0 0.0836603168464202 3 Q6NUK1,P49815 2 +Premature rupture of membranes 0.8400773099449333 2.298140186126173 0.0215538116950726 1.0 0.0844915175454855 6 Q9Y487 1 +Corneal dystrophy 0.7426710097719806 2.2977354842991993 0.0215768486599772 1.0 0.0844915175454855 4 P12235,Q13868,P06280 3 +Abnormal pulmonary interstitial morphology 0.5446292088572046 2.2960226036879336 0.021674588992981 1.0 0.0847692993529014 28 Q14108,P09601,Q8IZA0,Q13510,P14174 5 +Undetectable electroretinogram 0.7903272318094131 2.2951122650482714 0.0217266913680107 1.0 0.0849017855639212 5 O14773,P50897 2 +Abnormal exteroceptive sensation 0.4629885284295196 2.2932106858359034 0.0218358782400109 1.0 0.0851142433824026 52 P07196,Q9NR77,Q9NZJ7,P61978,P01889,Q8NCH0,O15269,P05067,P07602,O95831,Q9H6K4,Q9NZ08,P54802,P06280 14 +Toe walking 0.5669155146288571 2.292489585549023 0.0218774078260144 1.0 0.0851843340044317 23 Q9NZJ7,Q9H9S5,P07602,O95831,P50402,P35637,Q99720 7 +Young adult onset 0.739473292291114 2.2891667215400404 0.0220696673468665 1.0 0.08565509489259 10 O15118,P31483,Q9NZJ7,P38435,P36551,P07602,Q9H0U3 7 +Developmental regression 0.3695099214485279 2.2889034043008816 0.0220849654285102 1.0 0.08565509489259 133 P55795,P01889,P00846,Q9H9P8,P40855,O75306,P17900,Q13510,P16278,Q9GZY8,P07602,Q9NZ08,Q9Y5Y5,P13073,Q15067,Q8NI60,Q96JX3,Q9Y4P3,O95831,O75503,O14773,O95470,Q9NZJ7,P03886,Q9H936,O43681,Q05639,O75381,P06280 29 +Abnormal auditory evoked potentials 0.7392615164306031 2.2880808742359453 0.0221328118182797 1.0 0.0857692491260791 10 P07196,Q9NZJ7,Q15125,P07602,O60220 5 +Abnormality of coordination 0.3388690354449494 2.2863801818265883 0.0222320267138391 1.0 0.0860821117481819 327 P07196,Q15907,P50897,Q05086,Q14108,Q5T8D3,Q96CU9,Q9BPX6,P55795,Q6DKK2,P01889,Q01105,Q9H9S5,P00846,O43676,P40855,O75306,Q5XKP0,Q13510,P35637,P16278,Q99720,P00403,O15118,P31749,O95721,Q9NR77,Q8IV08,P05067,P07602,P61916,Q86Y39,Q9NZ08,Q9Y287,Q9Y487,Q9Y5Y5,O60313,Q15067,P04062,O75298,Q8NI60,Q8WXW3,Q9Y4P3,Q6P4A7,O95831,Q96D71,O75503,O14773,Q9BUB7,Q8N5M1,O14949,Q9NQZ5,Q8N2K0,Q96BR5,O95470,O00584,P48637,P31483,Q9Y619,Q9NZJ7,O15460,O95202,P03886,O75489,P00374,Q13501,Q9H936,O43681,Q10713,O43292,Q9H6K4,Q05639,Q9NVI7,Q96IX5,O75381,Q7RTS9 76 +Disproportionate short stature 0.5529140547354966 2.2858170852961783 0.0222649617260437 1.0 0.0861380329899599 26 O75718,Q32P28,Q14739,Q15125,Q8WVQ1,Q9UHX1,Q7LGA3,Q96HY6,O00116,P16278,Q15392,Q7RTS9 12 +Fluctuations in consciousness 0.7883481416498477 2.280275612306916 0.0225913472751428 1.0 0.0871113374235228 8 P03886,P00403,P04062 3 +Corneal erosion 0.7380944571686232 2.275267132679316 0.0228899098353216 1.0 0.0878265482359631 4 P51648,P01889 2 +Progressive gait ataxia 0.6969877577980589 2.274182329201572 0.0229550262507358 1.0 0.0880037138073478 12 Q05086,Q9NZJ7,P07602,P00846,O43681,O14773 6 +Paraplegia paraparesis 0.4072950487599018 2.27377268172956 0.0229796575705003 1.0 0.0880256948712094 75 Q9Y5Y5,O60313,Q9Y619,O75298,P04062,Q15041,O75489,Q96CU9,Q9H0B6,Q6DKK2,P00846,O95831,Q9H6K4,O75306,Q5XKP0,Q13510,P35637 17 +Bone cyst 0.6785079928952049 2.2647491413952263 0.0235280780095161 1.0 0.0891731386235364 3 P31749,P21912 2 +Conjunctival hamartoma 0.6785079928952049 2.2647491413952263 0.0235280780095161 1.0 0.0891731386235364 3 P31749,P21912 2 +Postaxial polydactyly 0.5625950959071576 2.2610835616803544 0.0237540831004168 1.0 0.0897376472682413 23 O43924,Q7Z4L5,P61978,Q15125,Q14739,O75845,Q10713,Q9Y263,Q9BRT2,P98175 10 +Tremor 0.3609020775602593 2.2587524455026338 0.0238987881259766 1.0 0.0902111467510529 174 P07196,Q05086,Q14108,Q9BPX6,Q6DKK2,P00846,O75306,Q13510,P35637,Q99720,P31749,Q9NR77,P07602,Q9Y287,O60313,P04062,Q8NI60,Q8WXW3,Q9Y4P3,Q6P4A7,O95831,P61457,O75503,O14773,Q9BUB7,O43464,O60220,Q9NQZ5,Q8N2K0,Q96BR5,P48637,Q9NZJ7,Q13501,P03886,Q9H936,O43681,Q10713,O43292,Q9H6K4,Q05639 40 +Undetectable light and dark adapted electroretinogram 0.7344551380578588 2.257358747779617 0.0239856671972773 1.0 0.0904657795991238 4 P00846 1 +Visual loss 0.4512830592016794 2.255872015323328 0.0240786475809451 1.0 0.0906696365659195 54 O60313,P31749,P50897,O15460,P04439,Q9NZJ7,P03886,P01889,O60220,P53701,P07602,P00846,Q10713,O75503,O75306,O14773,P00403 17 +Retinal dystrophy 0.4423967869930333 2.2532521330865145 0.0242432559924783 1.0 0.090826239107765 58 Q9Y5Y5,Q15555,Q13868,Q15067,P38435,Q5T8D3,P03886,Q6P4Q7,P53701,Q9H9S5,P00846,Q8IY17,O43505,Q10713,P40855,O75381,Q9Y287,Q8N2K0 18 +Hypocholesterolemia 0.7825863050280163 2.252934465890653 0.0242632813277858 1.0 0.090826239107765 8 P07602,Q15800,Q9NZJ7 3 +Ankylosis 0.8297082540999425 2.2524272722364587 0.0242952838920775 1.0 0.090826239107765 6 O75844,P22413,P16435 3 +Arthralgia 0.5035315938744931 2.2481460218926164 0.0245668802908427 1.0 0.090826239107765 35 P01889,Q9Y4P3,Q96HY6,P22413,Q15800,Q13510,Q9NZ08,P14174,P06280 9 +Microglossia 0.7325498416234197 2.2479685543146792 0.024578195138329 1.0 0.090826239107765 4 P48651 1 +Aplasia hypoplasia of the tongue 0.7325498416234197 2.2479685543146792 0.024578195138329 1.0 0.090826239107765 4 P48651 1 +Neuroinflammation 0.6753409134223717 2.2479496913486576 0.0245793980548816 1.0 0.090826239107765 3 P01889 1 +Pleuritis 0.6753409134223717 2.2479496913486576 0.0245793980548816 1.0 0.090826239107765 3 P01889 1 +Orchitis 0.6753409134223717 2.2479496913486576 0.0245793980548816 1.0 0.090826239107765 3 P01889 1 +3 methylglutaconic aciduria 0.6780484228771246 2.244367288294641 0.0248087794107938 1.0 0.0909573636249608 13 Q96JX3,Q3ZCQ8,Q9NVI7,Q9H6K4,Q9BUB7,Q5XKP0,O43464 7 +Pulmonary embolism 0.7314634986896117 2.2426100577677675 0.024921971099038 1.0 0.0911913129452625 4 P31749,P01889 2 +Abnormality of the 5th toe 0.7037352531001135 2.239284940664186 0.0251373820976212 1.0 0.0918352359299764 11 O43924,Q7Z4L5,Q14739,O75845,Q9Y263,Q10713 6 +Postaxial foot polydactyly 0.7037352531001135 2.239284940664186 0.0251373820976212 1.0 0.0918352359299764 11 O43924,Q7Z4L5,Q14739,O75845,Q9Y263,Q10713 6 +Buphthalmos 0.7306717094405117 2.2387024232404538 0.0251752847634143 1.0 0.0919016272946583 4 Q9H9S5 1 +Abnormal bone structure 0.3588298076477239 2.237130025871837 0.0252778430479183 1.0 0.0920932341826787 184 Q13277,Q14108,P61978,Q15125,P48651,Q96HY6,O75874,P40855,Q86XL3,Q13510,P16278,Q9NWM8,P31749,O75718,P22626,P53634,Q14739,Q8WVQ1,P07602,P51798,O00116,P48735,P54802,Q9Y487,Q9Y5Y5,Q9UG56,Q32P28,P04062,P38435,Q9Y4P3,O95831,O75844,Q9NSD9,P08236,Q15392,Q9Y619,Q9NZJ7,O95202,Q13501,O75845,Q9HC07,P22413,O43292,O75381,Q7RTS9,P06280 46 +Muscle abnormality related to mitochondrial dysfunction 0.498148545993729 2.2366000115944487 0.025312494169114 1.0 0.0920932341826787 38 O60313,Q9UBX3,Q96CU9,P03886,Q9Y2R0,P00846,O43676,O75306,Q86Y39,P00403 10 +Thickened skin 0.375670134756062 2.236384005355894 0.0253266279493369 1.0 0.0920932341826787 106 P00813,P51648,P09493,Q15125,O15269,P40855,P16278,Q9NWM8,P31749,O95721,Q14739,Q14574,Q15800,P50402,Q9Y5Y5,P04062,P98194,P31751,O75844,O95470,P04066,P22413,O75381,P06280 24 +Thoracic kyphosis 0.61777314052446 2.231952061701768 0.0256181314538297 1.0 0.0930805431450381 17 Q9UHX1,O95831,Q7RTS9,P04062 4 +Tissue ischemia 0.5659181705276062 2.2295806235297517 0.025775297397804 1.0 0.09343294574239 21 P01889,P05067,Q9Y4P3,P22413,O75844,Q9NZ08,P06280 7 +Pericarditis 0.7760852262738767 2.228797654728895 0.0258273710700198 1.0 0.093548907032778 5 Q9NZ08,P01889,P14174 3 +Abnormal morphology of the conjunctival vasculature 0.8236854049609312 2.2257658096523523 0.0260298720764182 1.0 0.0941359814689101 6 P10619,P04066 2 +Muscle weakness 0.3414205612612297 2.2246602103699575 0.026104057314493 1.0 0.094184894632772 301 P07196,P05023,P61978,Q5T8D3,Q96CU9,Q9BPX6,P01889,Q6DKK2,O15269,Q9H9S5,P00846,Q68CQ7,O43676,P40855,O75306,Q5XKP0,Q13510,P17900,P35637,Q99720,P00403,Q9NWM8,Q70HW3,P31749,P22626,Q9NR77,O95721,P36551,Q9BQT8,Q14739,Q9GZY8,Q969X5,P07602,O43505,Q4J6C6,P50402,Q86Y39,Q9Y5Y5,O60313,P13073,Q15067,Q92804,O75298,Q8NI60,Q8NCH0,Q3ZCQ8,O95831,Q71SY5,Q15165,Q96BR5,P31483,O15460,Q9NZJ7,O75489,Q13501,P03886,P00374,Q9H936,Q9UHX1,Q9HC07,Q10713,P10253,P06865,O43681,Q05639,O14979,O75381,Q7RTS9 68 +Ulnar claw 0.7272277396616493 2.2216856196819172 0.0263045590535806 1.0 0.0945421574626378 4 Q9NR77 1 +Abnormal subcutaneous fat tissue distribution 0.727086988219306 2.220989464353809 0.0263516749900174 1.0 0.0945861900947245 4 Q9Y487 1 +Functional abnormality of the inner ear 0.3460886143029669 2.2209046140556605 0.0263574226584268 1.0 0.0945861900947245 259 P07196,P09493,Q15125,P61978,Q96CU9,P01889,P42892,O15269,P00846,O43676,P40855,O75306,Q5XKP0,Q13510,P35637,P51572,Q9H061,P00403,Q9NWM8,O95721,Q9NR77,Q9Y297,P07602,Q86Y39,P38159,Q9NZ08,P0DP25,Q9Y5Y5,O60313,Q9UG56,Q15067,P04062,Q96JX3,Q7LGA3,Q9Y4P3,O95831,O75844,O43464,O60220,Q8N2K0,O95470,O00584,Q9NR28,Q15555,O15460,Q9NZJ7,O75489,O95202,P03886,Q13501,P22413,O75381,P06280 53 +Widely patent fontanelles and sutures 0.7741774412516891 2.219876519244978 0.0264271508255997 1.0 0.0947634091960305 5 O75844 1 +Abnormality of glycolipid metabolism 0.7987387210105781 2.216860516038083 0.0266326246161514 1.0 0.095115808020378 7 Q9NZJ7,P07602,P06865,P17900,P06280 5 +Areflexia of lower limbs 0.5640433696402875 2.2162183076947097 0.0266765546402192 1.0 0.095115808020378 21 P07196,O60313,Q9NR77,Q15067,Q15041,Q9H6K4 6 +Duodenal adenocarcinoma 0.6685077599727922 2.211594254394755 0.0269947127785754 1.0 0.0959103426075406 3 P25054 1 +Adenocarcinoma of the small intestine 0.6685077599727922 2.211594254394755 0.0269947127785754 1.0 0.0959103426075406 3 P25054 1 +Supranuclear gaze palsy 0.5665790736305328 2.209181208589098 0.0271620393928806 1.0 0.0962906696298576 20 O15118,P04062,Q9NZJ7,P07602,P61916,P35637,Q99720 7 +Onion bulb formation 0.7958575163018224 2.203603878381211 0.027552214299245 1.0 0.0973734553914138 7 Q9NR77 1 +Abnormality of central nervous system electrophysiology 0.3577885540311947 2.196224142167732 0.0280759041951135 1.0 0.098774593459848 166 P07196,P50897,Q14108,Q15125,Q9H9S5,P40855,P00403,Q9UBX3,Q9GZY8,P07602,Q2M389,Q9BQE5,Q9Y5Y5,O60313,P13073,Q08J23,Q15067,Q3ZCQ8,Q71SY5,O75503,O60220,Q96A33,Q9NQZ5,Q9NZJ7,O95202,P03886,Q96N66,Q13501,Q9H936,O43292,Q05639,O75381 32 +Spasticity 0.3360518282625359 2.195333401961881 0.0281396905551392 1.0 0.0989242857402554 321 P07196,P51648,P50897,Q96CU9,Q6DKK2,Q01105,P00846,Q9H9P8,Q68CQ7,P40855,Q86XL3,O75306,Q5XKP0,Q13510,P17900,P35637,P16278,Q99720,O15118,Q15041,Q9UBX3,Q9GZY8,P11117,P07602,O43505,P61916,Q2M389,Q9Y287,Q9Y487,Q9Y5Y5,O60313,Q08J23,Q92804,P04062,O75298,Q96JX3,Q9Y4P3,Q3ZCQ8,O95831,Q96D71,Q71SY5,O75503,Q16625,O43464,O60220,Q15392,Q15165,Q8N2K0,P48637,O00584,Q9Y619,Q9NZJ7,Q9H0B6,O75489,P03886,Q96N66,Q13501,Q9H936,P04066,O43681,Q10713,O43292,Q9H6K4,Q05639,Q9NVI7,Q9UNW9,O75381,Q7RTS9 68 +Nephrotic syndrome 0.5190352111717952 2.189963221243606 0.0285269042616465 1.0 0.0997584985365986 30 P00813,O95470,O95721,Q14108,Q8NCH0,Q9BT22,Q8N1F7,P06280 8 +Concave nasal ridge 0.6639542338951172 2.187284352686331 0.0287217722885724 1.0 0.1003457984040482 3 Q15125 1 +Abnormality of the wrist 0.496473919110432 2.1869151094789174 0.0287487217032316 1.0 0.1003457984040482 35 P31749,P16435,Q15125,Q8WVQ1,P16278,P22413,O95831,O75844,Q9H6K4,Q13510,Q7RTS9 11 +Abnormal heart rate variability 0.7201814890548672 2.1867678394687062 0.0287594763566776 1.0 0.1003457984040482 4 P07602 1 +Abnormal sensory nerve conduction velocity 0.7665432638273988 2.1840881317350584 0.0289557726169447 1.0 0.1006876388831033 5 Q9NR77 1 +Anterior rib cupping 0.7664194474516218 2.183506509929512 0.0289985300797674 1.0 0.1006876388831033 5 P00813 1 +Endocarditis 0.7664148004959364 2.1834846803327914 0.0290001359227431 1.0 0.1006876388831033 5 P01889,P04062 2 +Premature loss of primary teeth 0.6625391255442075 2.179715999611659 0.0292785198316396 1.0 0.1013012261785802 3 P53634 1 +Severe muscular hypotonia 0.499490336655598 2.179503579881902 0.0292942790172923 1.0 0.1013012261785802 33 Q9Y5Y5,Q9NWM8,Q01105,Q9H9S5,O43505,O95831,P40855,Q05639,O75381 9 +Underdeveloped supraorbital ridges 0.6526122276540679 2.1772431891543396 0.029462427448619 1.0 0.1018071120591005 14 Q9Y5Y5,P16435,P40855,O75381,P98175 5 +Abnormality of the achilles tendon 0.652464960883079 2.176379370890841 0.0295269050238606 1.0 0.1018787582230689 14 O60313,Q08J23,Q8TD16,Q9BTV4,Q15041,Q9H9S5,Q92734,P50402,Q13642,Q8N2K0 10 +Coxa vara 0.6237289209344252 2.174981279216809 0.0296315192982539 1.0 0.1021030371125155 16 O75718,P22413,Q96HY6,O95831,Q7RTS9,Q9Y487 6 +Deformed sella turcica 0.7645935097074851 2.1749248780300823 0.0296357462808332 1.0 0.1021030371125155 5 Q7RTS9 1 +Microretrognathia 0.5776597211928195 2.1736278742785267 0.0297330932994039 1.0 0.102293276659462 19 Q15125,Q8WVQ1,Q8NCH0,Q9UHX1,Q16625 5 +Caesarian section 0.717440394902931 2.1731473637455605 0.02976922790323 1.0 0.1023358402754578 4 P33991 1 +Cns demyelination 0.6650431896222502 2.1703850561372797 0.0299776879275517 1.0 0.1028006955723716 13 P51648,Q15067,P07602,Q9H9P8,P40855 5 +Ventricular preexcitation 0.76525537426789 2.170186347405805 0.0299927319198911 1.0 0.1028006955723716 8 P03886,P10253,P00846,O75306,P00403 5 +Pericardial effusion 0.7648805107846863 2.168388096755053 0.0301291705928554 1.0 0.1031165882597507 8 Q14108,P04062 2 +Flattened epiphysis 0.7151293184509755 2.1616475869402376 0.0306453504892973 1.0 0.1044672631691517 4 O95831 1 +Congenital ichthyosiform erythroderma 0.809236654825926 2.1614786664481347 0.0306583831584865 1.0 0.1044672631691517 6 Q15125 1 +Abnormality of circulating leptin level 0.7142144884421526 2.157091393626064 0.0309985440623177 1.0 0.1054996332022899 4 O75844 1 +Frequent falls 0.484392324410512 2.1545632940275836 0.0311960240010513 1.0 0.1058423941754541 41 Q9NR77,P04062,Q9H9S5,P00846,P07602,Q13510,Q7RTS9 7 +Progressive visual loss 0.5399775627040759 2.154534440636035 0.0311982840710387 1.0 0.1058423941754541 25 P31749,P50897,P03886,P00846,O75503,O75306,O14773 7 +Deep plantar creases 0.7597939830988694 2.1523288095222277 0.031371466314255 1.0 0.1062625834286713 5 Q9Y487 1 +Cerebral white matter atrophy 0.5511942137331698 2.149959929841763 0.0315583844715634 1.0 0.1064438485652009 22 Q9Y5Y5,O60313,O43175,Q9H9P8,P51572,Q9Y263,O75503,P51970,P20700,Q2TAA5 10 +Neuronal loss in central nervous system 0.6858568859189278 2.142532145210725 0.0321506848124477 1.0 0.1082848082837177 11 O15118,P35637,P07602,P04062 4 +Pathologic fracture 0.6323903633546377 2.13993285629069 0.0323601933602963 1.0 0.1088330546370112 15 P22626,Q14108,P04062,O75845,O15269 5 +Morphological abnormality of the corticospinal tract 0.6320229837144226 2.137706914039166 0.0325405380068977 1.0 0.1092030446946178 15 Q9Y4P3,P00846,P35637,O75298 4 +Abnormal speech prosody 0.7577225375259229 2.1339824103556806 0.0328442206983479 1.0 0.1099825071792748 8 P00846,P04062 2 +Lower limb spasticity 0.3994349278854811 2.1337011742902963 0.0328672498912732 1.0 0.1099825071792748 80 Q9Y5Y5,O60313,Q9Y619,P04062,O75298,Q15041,Q9H0B6,Q96CU9,Q9NZJ7,Q6DKK2,P07602,P00846,O95831,Q9H6K4,O75306,Q5XKP0,P35637,Q99720 18 +Abnormal neuron morphology 0.5177130652988811 2.130447135556707 0.0331347158501675 1.0 0.1106390727097351 29 P22626,P31483,Q92804,Q13501,P50995,Q68CQ7,Q13510,P35637,Q15165,Q99720 10 +Constriction of peripheral visual field 0.5484690032073307 2.130110666354848 0.0331624779336459 1.0 0.1106524514433543 22 Q9Y5Y5,O60313,P00846,P40855,O60220,O75381,Q9H061 7 +Very long chain fatty acid accumulation 0.779683099350976 2.1288203950502784 0.0332691228693053 1.0 0.1109288291519144 7 Q9Y5Y5,O75381,P40855 3 +Abnormal femoral neck morphology 0.4857709207161842 2.126354788701366 0.0334737292623659 1.0 0.1114323544801038 38 O75718,Q9Y619,P04066,P22413,Q96HY6,O95831,O75844,P16278,Q96A33,Q7RTS9,Q9Y487 11 +Y shaped metacarpals 0.6524511531694247 2.125577785387411 0.0335384309331348 1.0 0.1114323544801038 3 O43924 1 +Abnormal circulating non proteinogenic amino acid concentration 0.7559747879117078 2.125561943916826 0.0335397511767079 1.0 0.1114323544801038 8 P03886,P00846,Q9Y619 3 +Urinary glycosaminoglycan excretion 0.7785746712596503 2.123672950898547 0.0336975007335862 1.0 0.1118766631625407 7 P15586,P54802,P16278,P04066 4 +Fasciculations 0.4855135704042586 2.1209168448226765 0.0339288008471341 1.0 0.1124842379686482 39 P07196,P22626,Q9NZJ7,Q9BQT8,Q969X5,P07602,O95831,Q13510,P35637,P06280 10 +Abnormality of the biliary system 0.3657280075029531 2.1203756001558296 0.0339743827110119 1.0 0.1125552451407493 117 Q14108,P40855,Q5XKP0,Q13510,O15118,P36551,P09601,P22830,Q14739,P07602,P61916,P14174,Q9Y5Y5,P04062,Q9Y4P3,Q16625,Q71SY5,Q9NSD9,Q96A33,Q9NZJ7,O95202,P00374,P04066,O75845,Q10713,O75381 26 +Progressive neurologic deterioration 0.549905727941925 2.114823234278047 0.0344450158428628 1.0 0.1136141702790303 21 P04062,Q9NZJ7,P07602,O43681,Q10713,Q5XKP0,P16278,Q9Y287,P54802 9 +Scaphocephaly 0.7057326796885485 2.114739565949462 0.0344521501773849 1.0 0.1136141702790303 4 P40855 1 +Restless legs 0.650318792454624 2.11409275839636 0.034507345579771 1.0 0.1136141702790303 3 O43464 1 +Reduced forced vital capacity 0.7055889659449377 2.1140202704200237 0.0345135360551369 1.0 0.1136141702790303 4 Q9H9S5 1 +Abnormal full field electroretinogram 0.7762743314329442 2.1129811683396884 0.0346023797326384 1.0 0.1137458608289555 7 P00846,P50897 2 +Abnormal light and dark adapted electroretinogram 0.7762743314329442 2.1129811683396884 0.0346023797326384 1.0 0.1137458608289555 7 P00846,P50897 2 +Tetraparesis 0.4858760693622296 2.1119561378115512 0.0346902116157843 1.0 0.1139541648140504 36 P48637,O75489,Q9NZJ7,Q9UBX3,P07602,P00846,Q9H9P8,P17900,P35637,Q7RTS9 10 +Joint contracture of the 5th finger 0.6495447118905182 2.10991994202307 0.0348652522384609 1.0 0.1144484460371747 3 Q9Y2B2 1 +Spastic tetraparesis 0.5335002727041117 2.10538774526917 0.0352575696622465 1.0 0.1150809046308443 25 P48637,P07602,P00846,Q9H9P8,P17900,Q7RTS9 6 +Nasogastric tube feeding in infancy 0.7038889280770069 2.104842923457146 0.0353049834086467 1.0 0.1150809046308443 10 Q9UHX1,P07602,Q9NZJ7 3 +Abnormal lower motor neuron morphology 0.7267238503093434 2.0977509451188907 0.0359271519449744 1.0 0.1169452646818245 9 Q13510,P35637,Q99720 3 +Poor wound healing 0.747877842304933 2.0959842018270822 0.0360835924004605 1.0 0.117357539878356 5 P04062 1 +Retinal degeneration 0.4233367405018579 2.092867117122477 0.0363610183506208 1.0 0.1181099187428117 60 P51648,Q9UG56,P50897,P04062,Q8N3R9,Q9H9S5,Q7LGA3,Q10713,O75503,O14773,Q13510,Q05639 12 +Abnormal cochlea morphology 0.6460272603353254 2.0909345904380467 0.0365339278219276 1.0 0.1185888751181456 3 Q9Y619 1 +Abnormal thoracic spine morphology 0.5068101813586069 2.0900691540208354 0.0366115880780195 1.0 0.1186755582932603 30 P04062,Q9UHX1,O95831,O75844,Q7RTS9 5 +Sensory axonal neuropathy 0.6504838941801412 2.086846192891629 0.0369020400392241 1.0 0.1192191669266717 13 Q9H0B6,O95831,Q15067,Q8IV08 4 +Depression 0.3654318190870023 2.086788416884108 0.0369072646432504 1.0 0.1192191669266717 108 P50897,P01889,Q6DKK2,Q68CQ7,P35637,P00403,P36551,P07602,Q2M389,Q08J23,Q92804,P04062,Q9Y4P3,Q71SY5,O43464,Q15165,O15460,Q9NZJ7,Q13501,P03886,Q96N66,P06280 22 +Xerostomia 0.6088310701668165 2.081922823362031 0.0373495196952771 1.0 0.120298295282208 16 Q92804,Q14739,Q13501,Q68CQ7,P35637,Q15165 6 +Dysostosis multiplex 0.6993656820730376 2.0811442977383696 0.0374207002486659 1.0 0.120298295282208 10 P10619,P04066,P15586,P16278,P54802 5 +Reduced visual acuity 0.3596670579748005 2.081128794221943 0.0374221189059509 1.0 0.120298295282208 127 Q13277,P50897,Q15058,Q96CU9,P01889,Q9H9S5,P00846,O43676,O75306,P17900,P16278,Q9H061,Q9BV73,Q96AA3,P31749,Q8N183,Q9NX14,P07602,P51798,O43505,Q86Y39,Q9NZ08,O60313,Q9NPL8,Q8WWV3,Q86YV9,Q71SY5,O60220,Q15555,P09622,Q9NZJ7,O75489,P03886,Q9UHX1,P53701,Q10713,O43681,P06865,Q96S66,Q9H6K4 40 +Atrophy degeneration involving the corticospinal tracts 0.6482189466793375 2.0737825744466214 0.0380995082345476 1.0 0.122307036083062 13 Q9Y4P3,P00846,P35637,O75298 4 +Erythroderma 0.7215804493850304 2.071860733144015 0.0382784308448547 1.0 0.1226272687278222 9 P00813 1 +Capillary hemangioma 0.7448463187791401 2.0717655648122477 0.038287309508217 1.0 0.1226272687278222 8 Q9UHX1,P31749,Q7LGA3 3 +Aplasia hypoplasia involving the vertebral column 0.6341446243797675 2.06828242294181 0.0386134736125176 1.0 0.1234465065800324 14 Q14739,P04066,Q96HY6,O95831,P16278,Q7RTS9 6 +Psoriasiform dermatitis 0.7418835533055695 2.067509901309775 0.0386861321916198 1.0 0.1235939669057375 5 P10321,P01889,Q15800 3 +Frontotemporal dementia 0.6719377673871761 2.066492716682378 0.0387819794152706 1.0 0.1237304521344729 11 P22626,P31483,Q13501,P05067,P35637 5 +Abnormality of the lymphatic system 0.3504970585593989 2.0637247248041612 0.039043823716734 1.0 0.1244039053804052 146 P10619,P00813,Q14108,P01889,P15586,Q96HY6,O75874,Q13510,P16278,O15118,P31749,P36551,Q14739,P07602,P61916,P48735,Q9NZ08,P14174,P54802,P04062,P31751,Q16625,P08236,P33991,Q15392,Q96A33,Q9NZJ7,O95202,P04066,O75845,P10253,Q10713,Q01844 33 +Hydranencephaly 0.6409117821195972 2.0632541617524174 0.0390884866666187 1.0 0.1244039053804052 3 O43175,Q92917 2 +Microcornea 0.4859080668482665 2.062542969456087 0.0391560710081584 1.0 0.1244975964204791 33 Q9NWM8,Q15125,Q8NCH0,O75845,Q9H9S5,O43505,Q71SY5 7 +Peripheral neuropathy 0.3501682845110443 2.060244983644721 0.0393751264995525 1.0 0.1251086897918934 161 P07196,Q96CU9,Q9BPX6,P01889,Q9Y2R0,O15269,P00846,O75306,P00403,P22626,O95721,Q9NR77,P36551,Q15041,Q9GZY8,Q8IV08,P07602,P54802,O60313,Q15067,O95831,O60220,Q8N2K0,O95470,O15460,Q9NZJ7,Q9H0B6,O75489,P03886,P04066,O43681,Q10713,Q9NVI7,Q96BR5 34 +Dilatation of the cerebral artery 0.7191199955917544 2.059450259281428 0.0394511253308551 1.0 0.1252403863874568 9 P38435,Q9NSD9 2 +Abnormality of temperature regulation 0.3639694239497937 2.058560597827406 0.0395363506087214 1.0 0.1253644119369804 104 P00813,P61978,P01889,P00846,Q5XKP0,Q13510,P51572,P00403,Q9NR77,Q14739,P07602,P14174,Q14C86,Q8NFH4,Q9NZJ7,P03886,P10253,Q9HC07,P22413,Q8N1F7,P06280 21 +Thickened nuchal skin fold 0.6188269830209537 2.057397824195902 0.0396479742765567 1.0 0.1256328327756471 15 Q9Y5Y5,P61978,Q15125,P22413,P40855,O75381 6 +Vitiligo 0.763854589687865 2.055041394494371 0.0398750066831177 1.0 0.126266336594128 7 P00403 1 +Left ventricular hypertrophy 0.5137463588602315 2.0526593555983097 0.0401056265611867 1.0 0.1267381333256499 28 P12235,P06280,O75880,Q6NUK1,P03886,P00533,P10253,Q9H9S5,P21912,O00170,P78536,Q15233,O75208,P00403 14 +Abnormality of the tarsal bones 0.5021031001535997 2.051322172938623 0.0402355825733302 1.0 0.1268905508643008 30 P16435,Q14739,Q15125,Q8WVQ1,Q9UHX1,O75844,Q7RTS9,P98175 8 +Abnormality of the larynx 0.4429986562814493 2.049127253606399 0.0404496731491734 1.0 0.1274794164606563 51 O00192,P16435,Q92804,Q14739,Q9NZJ7,Q13501,P50995,P21964,P07602,Q68CQ7,Q96HY6,P54198,Q9UHX1,Q8NCM8,Q13510,P35637,Q15165 17 +Spastic paraparesis 0.5439469250489796 2.0482259560866907 0.0405378642670504 1.0 0.1276338824628924 20 Q9Y5Y5,Q9Y619,P04062,Q6DKK2,Q9H6K4 5 +Increased circulating antibody level 0.6171223855079342 2.0469736566334618 0.0406606711513766 1.0 0.1277985197186992 15 P00813,Q14108 2 +Chronic diarrhea 0.5888815717160945 2.04611086486985 0.0407454642794022 1.0 0.1278964519948147 17 P00813,Q13277,Q08J23,Q13510,Q96A33 5 +Cerebral inclusion bodies 0.630410901283029 2.0460978524102376 0.0407467442594042 1.0 0.1278964519948147 14 O15118,P22626,P04062,P05067,P61916,Q9Y287 6 +Skeletal dysplasia 0.4526841128131055 2.044483764184158 0.0409057797292267 1.0 0.1283091730496552 48 P10619,P51648,P31749,Q9Y5Y5,Q14739,Q9HC07,P22413,Q96HY6,O95831,P40855,P16278,O75381,Q7RTS9 13 +Vertebral segmentation defect 0.49525201169001 2.0439807966461103 0.0409554442844479 1.0 0.1283440807811522 31 Q9Y619,P16435,P61978,Q15125,O95202,Q9UHX1,Q9H9S5,P22413 8 +Nephropathy 0.5582162703082774 2.039717801823967 0.0413784408115454 1.0 0.1291828266086987 19 Q7Z4L5,P06280,Q14108,P36551,P03886,P62258,Q10713,O76024,P00403 9 +Abnormal visual fixation 0.7377457664910595 2.0372781929206663 0.0416221718722373 1.0 0.1298567157273152 8 Q13510 1 +Abnormality of the tongue 0.3625865711610598 2.0362593734136487 0.0417243170523209 1.0 0.1300882146564843 98 P07196,Q05086,P61978,P01889,Q9H9S5,P40855,Q13510,P16278,P31749,Q9BQT8,Q9Y5Y5,Q7LGA3,Q9Y4P3,O95831,O75844,Q71SY5,Q96A33,P98175,O15460,P04066,P10253,Q10713,O75381 23 +Psychotic mentation 0.7352675511154508 2.03598134436173 0.0417522286198892 1.0 0.1300882146564843 5 P03886,P00403 2 +Myoclonic seizure 0.4283803087230179 2.0320678102277605 0.042146791600498 1.0 0.1311421210922645 55 Q9Y619,P04062,Q9NZJ7,Q8WWV3,Q96N66,P03886,Q9H936,Q01105,P16278,P07602,P00846,O43292,Q9H3H1,O75503,Q5XKP0,Q13510,Q05639,Q8TAB3 18 +Flat face 0.5150854368950193 2.0281395242284135 0.0425460100189141 1.0 0.1321195431120679 27 Q9Y5Y5,Q9NX62,Q15125,P40855,Q9BUB7,P08236,O75381,Q9Y487 8 +Hypoplastic hippocampus 0.6338069863824808 2.0246728659374043 0.0429009666263666 1.0 0.1331330463328554 3 Q9UID3,Q9HA77 2 +Increased serum lactate 0.360995425534164 2.0213631815541744 0.0432421831382459 1.0 0.1340133659733529 109 Q9BWD1,Q96CU9,P20674,P00846,O75306,Q5XKP0,P00403,Q70HW3,O75880,Q9UBX3,Q86Y39,O75208,P13073,Q8NI60,Q96JX3,Q6P4A7,O95831,Q3ZCQ8,Q9BUB7,O43464,Q8N5M1,O14949,O75489,P03886,P22695,Q9BW92,Q9NVI7 27 +Hypoplasia of the musculature 0.7319765224940441 2.0202586801124265 0.0433565623930309 1.0 0.1342785024113951 5 Q9NR77 1 +Blurred vision 0.731370174404833 2.0173590575550335 0.0436580566462196 1.0 0.1350216223977743 5 O75306,P03886,P00846 3 +Contractures of the large joints 0.6320307874481946 2.015002884381212 0.043904346854203 1.0 0.1355244848554526 3 Q9Y263,O75431 2 +Alkalosis 0.6851438499141147 2.011119578339182 0.0443128276685893 1.0 0.1364392421156666 4 Q9Y619 1 +Parkinsonism 0.4971505914269712 2.0103846717567286 0.0443904915306996 1.0 0.1365725954755607 30 P04062,Q9NZJ7,Q13501,O96008,P05067,P07602,P61457,O75569,O43464,P35637,Q8TAB3,Q99720 12 +Posterior embryotoxon 0.5319231566259232 2.008688980957918 0.0445701280318142 1.0 0.137034756681314 22 Q9Y5Y5,O00192,Q9NX14,Q96DF8,P53701,Q7LGA3,Q9Y4P3,P54198,P40855,O75381 10 +Hepatomegaly 0.3465971871364667 2.007753972724356 0.0446694421107678 1.0 0.1372495127651428 175 P00813,O60762,Q14108,Q96CU9,P20674,P15586,P00846,Q9BT22,Q96HY6,O43676,P40855,O43772,O75306,Q13510,P16278,Q96AA3,O15118,Q8N183,O75880,Q9NX14,P09601,P36551,Q14739,P07602,P51798,P61916,Q96EY8,Q86Y39,P14174,P54802,Q9Y5Y5,P50416,Q15067,Q9NPL8,P04062,P31751,Q16625,Q9H0U3,Q9BUB7,P28288,P08236,P33991,Q8N5M1,Q96A33,P09622,Q9Y619,Q9NZJ7,O75489,P03886,P00374,P04066,O75845,P10253,Q9HC07,Q10713,Q01844,Q9NVI7,O75381 58 +Recurrent aspiration pneumonia 0.7740194966620676 2.0028697336624863 0.045191272504149 1.0 0.1385786354998854 6 Q13510,P78318,P04062 3 +Wide anterior fontanel 0.50143456430392 1.9985505174674791 0.045657008856569 1.0 0.1397308457647167 29 Q9Y5Y5,O75718,Q08J23,Q32P28,P16435,Q15125,P40855,O75381,Q9Y487 9 +Progressive psychomotor deterioration 0.728740336388612 1.993358192570369 0.0462222384103263 1.0 0.1406419322223614 8 Q9NZJ7,P07686,P07602,Q10713,O43681,P16278 6 +Axial dystonia 0.6279744186150946 1.9928824279225696 0.0462743229251545 1.0 0.1406419322223614 3 P35637 1 +Distal peripheral sensory neuropathy 0.7262590082591551 1.9928819521174228 0.0462743750388274 1.0 0.1406419322223614 5 P00403 1 +Achilles tendon contracture 0.6464974151094467 1.9921752028532604 0.0463518379765113 1.0 0.1406419322223614 12 O60313,Q08J23,Q8TD16,Q9H9S5,P50402,Q8N2K0 6 +Recurrent bacterial skin infections 0.681375082585157 1.9920283395338152 0.0463679485576737 1.0 0.1406419322223614 4 P78536,P53634 2 +Abnormal foot bone ossification 0.6813038165565383 1.9916669658346544 0.0464076105250685 1.0 0.1406419322223614 4 Q14739,Q15125 2 +Duplication involving bones of the feet 0.5103150556817853 1.9904344887741416 0.0465430938580875 1.0 0.140960813518187 27 O43924,Q7Z4L5,O00192,Q14739,Q15125,O95202,O75845,P21964,Q8WXW3,Q10713,Q9Y263,P54198 12 +Abnormality of chorioretinal pigmentation 0.7249161304935585 1.986440644034484 0.0469844174048763 1.0 0.141928285520048 5 Q9Y619 1 +Abnormal pupillary function 0.7702257669617282 1.9856235421480033 0.04707514039388 1.0 0.1420181372763557 6 P07602,Q9NR77 2 +Hamartoma of tongue 0.6800346887845207 1.98522924441529 0.0471189720358318 1.0 0.1420583635876405 4 O43924,Q8NCM8 2 +Abnormal circulating long chain fatty acid concentration 0.7700360820686234 1.9847604319274408 0.0471711316904654 1.0 0.1421236296340157 6 Q9Y5Y5,P40855 2 +Atrophy degeneration involving the caudate nucleus 0.7698496068712641 1.9839118516906356 0.0472656674732818 1.0 0.1423164053591124 6 P00846 1 +Emg neuropathic changes 0.5208016422629059 1.9789770486163551 0.0478185903946317 1.0 0.1434249800761073 24 O60313,P22626,Q9NR77,Q9NZJ7,Q969X5,P07602,O14773,Q13510 8 +Dysesthesia 0.767812993684719 1.9746391437583235 0.0483091135872761 1.0 0.1440613643338876 6 Q9NR77 1 +Personality changes 0.5626393654204029 1.9681653424105203 0.0490490165418677 1.0 0.1457081116403189 18 P31483,P04062,P03886,O60220,P00403 5 +Abnormality of the peripheral nervous system 0.3571693482802456 1.967153018955307 0.0491655724274868 1.0 0.1459612723819208 111 P07196,Q15125,P42892,O15269,Q99720,O95721,Q9NR77,Q9GZY8,P07602,P0DP25,O60313,Q15067,P04062,Q8WXW3,O95831,Q71SY5,O43464,O60220,Q9NQZ5,Q8N2K0,Q96EK5,Q9Y619,Q9NZJ7,Q10713,P06280 25 +Torsade de pointes 0.6230091169560958 1.9657360583468388 0.0493291073016874 1.0 0.1463534915995288 3 P0DP25 1 +Severe photosensitivity 0.5693992305415867 1.9568133221716 0.050369420198943 1.0 0.1486823569624061 2 P06132 1 +Involuntary movements 0.3190048340069298 1.9560104366874855 0.0504639246652625 1.0 0.148866979791509 346 P07196,Q15907,P50897,Q05086,Q14108,Q9BWD1,Q96CU9,Q9BPX6,P55795,Q6DKK2,Q01105,Q9H9S5,P00846,O75306,Q5XKP0,Q13510,P17900,P35637,Q99720,P00403,P31749,P22626,Q9NR77,P27544,Q9BQT8,Q9UBX3,Q969X5,P05067,P07602,P61916,Q2M389,Q9Y287,O60313,P13073,Q08J23,P04062,O75298,Q8NI60,Q8WXW3,Q9Y4P3,Q6P4A7,O95831,Q3ZCQ8,Q71SY5,O75503,O14773,P61457,O43464,O60220,O14949,Q9BUB7,Q9NQZ5,Q8N2K0,Q96BR5,P48637,O00584,Q9Y619,Q9NZJ7,O95202,P03886,Q96N66,P00374,Q13501,O75845,Q9H936,Q9UHX1,O43681,Q10713,O43292,Q9H6K4,Q05639,Q96IX5,Q9UNW9,P06280 74 +Progressive sensorineural hearing impairment 0.6514761577913355 1.9535912735426149 0.0507495734683918 1.0 0.1496148817821323 11 O60313,P03886,Q9NSE4,O76024,O60220,P49736,P00403 7 +Hypertonia 0.3059850806605311 1.9529725763047687 0.0508228448123992 1.0 0.1497361234257785 386 P50897,Q15125,P00846,Q9H9P8,Q13510,Q9UBX3,P07602,Q2M389,Q9Y487,Q9Y5Y5,P04062,Q96JX3,O95831,O75503,Q9Y619,P03886,P06865,Q7RTS9,P51648,Q6DKK2,Q68CQ7,Q86XL3,P17900,P35637,Q15041,P05067,Q9Y287,Q15067,Q92804,O75298,Q7LGA3,Q96D71,O43464,O60220,Q8N2K0,O00584,Q9H0B6,P04066,Q10713,O43292,Q9H6K4,Q05639,P07196,Q96CU9,Q9BPX6,Q9H9S5,P40855,Q5XKP0,O15118,P11117,O43505,P61916,O75208,Q3ZCQ8,Q71SY5,Q15392,Q15165,P48637,Q9NZJ7,Q96N66,Q9NVI7,O75381,P55795,Q01105,O75306,P16278,Q99720,Q14739,Q9GZY8,O60313,Q08J23,Q9Y4P3,Q16625,P61457,O75489,Q13501,Q9H936,Q9BW92,O43681,Q9UNW9 80 +Fatigable weakness of swallowing muscles 0.6146697708212345 1.9520007907731591 0.050938110727801 1.0 0.1499808595259781 14 Q92804,Q13501,Q68CQ7,P35637,Q15165 5 +Mild postnatal growth retardation 0.568215448357508 1.949788523004968 0.0512013300597118 1.0 0.1505655274104405 2 P10644 1 +Delayed epiphyseal ossification 0.6729386953602643 1.9491556992804908 0.0512768336225495 1.0 0.1505974092142722 4 Q96HY6 1 +Abnormal cellular phenotype 0.3415663537087764 1.9458744249222375 0.0516698257546142 1.0 0.1514591238336379 195 P00813,Q14108,Q96CU9,Q9Y2R0,P15586,P00846,O43676,O75306,Q13510,P35637,P00403,P31749,Q70HW3,O75880,P09601,Q14739,Q9UBX3,Q96DF8,Q9GZY8,P07602,Q4J6C6,Q86Y39,P14174,P13073,P04062,Q3ZCQ8,O75844,O75503,O14773,Q9BUB7,P33991,O60220,Q9NZJ7,O75489,P03886 35 +Abnormal metatarsal morphology 0.4780060148030173 1.945620837893577 0.0517003020385324 1.0 0.1514591238336379 32 P31749,Q08J23,P16435,O95202,Q8WVQ1,Q9H9S5,O43505,Q15392,Q7RTS9 9 +Mitochondrial myopathy 0.4887903450480977 1.940884016596642 0.0522723471314838 1.0 0.152750685657749 30 Q9Y6M9,O60313,P12235,P56556,Q8N183,Q9NPL8,Q9NX14,O75489,P03886,Q96CU9,P00846,O43676,O75306,Q86Y39,P00403 15 +Slow saccadic eye movements 0.6486090667409746 1.9376662551003012 0.0526639534405233 1.0 0.1535880187202808 11 Q8IV08 1 +Muscle stiffness 0.5721940612564044 1.937080957825584 0.0527354479260495 1.0 0.1535880187202808 17 P07602,P00846,P53985,Q15392 4 +Abnormal sternum morphology 0.3546709203792295 1.936702483476796 0.0527817220161268 1.0 0.1535880187202808 114 P61978,P55795,Q13510,P16278,P31749,O75718,Q14739,P50402,Q9Y487,Q08J23,P04062,Q8NCH0,Q7LGA3,Q9Y4P3,O95831,Q71SY5,Q9NSD9,P08236,Q96A33,P98175,Q9Y619,O95202,Q9UHX1,Q9NVI7,Q7RTS9 25 +Ichthyosis 0.4661801399009617 1.9359879553214696 0.0528691761702984 1.0 0.1535880187202808 36 Q9Y5Y5,P51648,O95470,P04062,Q15125,Q15800,P40855,P50402,O75381 9 +Bone pain 0.5111618405274536 1.933914410151625 0.053123652077152 1.0 0.1540784379672319 25 Q14108,P04062,Q9NZJ7,Q13501,P07602,P22413,O75874,P48735 8 +Limb pain 0.6937584554476599 1.9305809147341504 0.0535348999402223 1.0 0.1551745886257346 9 P00846,O15269,P36551 3 +Ankle clonus 0.6229710573791747 1.9269384024690948 0.0539873069080578 1.0 0.1560005431623657 13 P07602,O60220,O75298 3 +Abnormal mitochondria in muscle tissue 0.5174664193691119 1.9265074243501787 0.0540410457146813 1.0 0.1560590148412807 23 Q9Y6M9,Q8N183,Q9NPL8,Q9NX14,O75489,P03886,Q96CU9,Q9Y4W6,O43676,O75306,Q86Y39,P00403 12 +Mesoaxial hand polydactyly 0.5640722107132354 1.925162291296988 0.0542090580016121 1.0 0.1563503357099135 2 Q9NQ48 1 +Abnormality of the middle phalanges of the toes 0.5640722107132352 1.9251622912969863 0.0542090580016123 1.0 0.1563503357099135 2 Q9ULC3 1 +Generalized hyperkeratosis 0.75551865765047 1.918476289250892 0.0550506458009059 1.0 0.1584832559583558 6 O75844,P04066 2 +Abnormality of the upper respiratory tract 0.3547025554005014 1.9177519249568085 0.0551424742613733 1.0 0.1584979767844407 102 P00813,P01889,P15586,Q68CQ7,Q96HY6,P16278,Q13510,P35637,P16435,Q14739,P07602,P54802,Q92804,Q86YV9,P08236,Q15165,O15460,Q9NZJ7,Q13501,P04066,Q9UHX1,Q7RTS9 22 +Psychomotor deterioration 0.691237163232709 1.9176763316297436 0.0551520646644794 1.0 0.1584979767844407 9 P07602,P50897,P06865,Q9Y487 4 +Abnormal femoral neck head morphology 0.4430296292760687 1.917362716190523 0.0551918673989615 1.0 0.1584979767844407 47 O75718,Q9Y619,Q14739,P04066,Q7LGA3,Q96HY6,O95831,P22413,O75844,P16278,Q96A33,Q7RTS9,Q9Y487 13 +Cerebellar atrophy 0.343666942094721 1.9160176113700849 0.055362854048292 1.0 0.1587932106877734 139 Q14108,Q96CU9,Q6DKK2,Q9H9S5,Q9H9P8,Q5XKP0,P51572,Q9GZY8,Q8IV08,O75208,Q9Y5Y5,O60313,P13073,Q8NI60,Q96JX3,Q96D71,O75503,O14773,Q8N2K0,P46977,Q96BR5,Q13501,O75845,Q10713,O43292,Q9H6K4,Q9NVI7 27 +Abnormal lower limb bone morphology 0.3404565535108204 1.9136313859104357 0.0556672717997861 1.0 0.1592500668503461 188 P00813,Q9NX62,Q15125,Q9H9S5,Q96HY6,Q13510,P16278,P31749,O75718,P16435,Q14739,Q8WVQ1,Q969X5,P07602,O43505,Q9Y487,P13073,Q08J23,Q32P28,P04062,Q8N3R9,Q8WXW3,Q7LGA3,O95831,O75844,Q71SY5,P08236,Q15392,Q96A33,P98175,Q9Y619,Q9NZJ7,O95202,P04066,O75845,Q9UHX1,Q10713,P22413,Q7RTS9,P06280 40 +Abnormal electroretinogram 0.4742679209967511 1.9133337820458969 0.0557053356167969 1.0 0.1592500668503461 32 O43924,Q15555,P50897,Q15067,Q04837,P00846,Q8IY17,Q96S66,O14773,O60220 10 +Abnormality of hepatobiliary system physiology 0.385236759679493 1.9131358631827189 0.0557306616304025 1.0 0.1592500668503461 83 Q8TCJ2,P01889,P00846,Q9BT22,P40855,O75306,Q5XKP0,Q13510,O15118,P22830,Q9Y5Y5,P50416,Q8N511,P04062,Q16625,Q9NSD9,P28288,Q96A33,P09622,Q9Y619,O15460,P03886,P22695,O75845,Q10713,O75381 26 +Exaggerated startle response 0.667573913717596 1.9128953159372415 0.0557614553527081 1.0 0.1592500668503461 10 P17900,Q9H0B6,P07686,P06865,P16278 5 +Hand polydactyly 0.4620473213693293 1.9114750185342504 0.0559435641655408 1.0 0.1596722560558143 38 O43924,Q7Z4L5,O00192,Q15067,Q14739,Q15125,O95202,O75845,P21964,Q8WXW3,Q9UHX1,Q8IY17,P54198,Q10713,Q9Y263,O60826,P98175 17 +Abnormal urine protein level 0.4071305577728247 1.9084712273065831 0.0563303385318012 1.0 0.1605704259387952 60 O95470,O95721,P06280,Q14108,P04062,P09601,P03886,Q8N1F7,Q8NFH4,P00403,Q14C86 11 +Dysmetria 0.4167596889543034 1.9051703719579776 0.0567579281815922 1.0 0.1616005070109147 55 Q9Y5Y5,O60313,Q13501,Q6DKK2,Q8IV08,Q9Y4P3,Q6P4A7,Q96D71,Q10713,O43292,O75503,O14773,Q96BR5,Q8N2K0 14 +Shuffling gait 0.6425406603849266 1.9038756519302336 0.0569263808204592 1.0 0.161938092050866 11 O75844,P04062 2 +Aortic valve stenosis 0.6869113937269088 1.895497353778726 0.0580265419851084 1.0 0.1646197110113175 9 Q15125,P04062 2 +Hemivertebrae 0.628273690865377 1.8882968005307976 0.0589861166090373 1.0 0.1667216815320969 12 Q15125,Q9Y619 2 +Abnormal peripheral nervous system morphology 0.3402714947615892 1.8867375696775064 0.0591956318070245 1.0 0.1671908460532779 163 P07196,Q9BPX6,Q6DKK2,O15269,Q9H9S5,P00846,P40855,Q13510,P35637,Q99720,P00403,P31749,P22626,O95721,Q9NR77,Q9BQT8,Q9GZY8,Q8IV08,P07602,Q9Y5Y5,Q15067,O95831,Q71SY5,Q8N2K0,Q9Y619,Q9NZJ7,Q9H0B6,P03886,Q9UHX1,Q9NVI7,Q96BR5,O75381 32 +Decreased number of peripheral myelinated nerve fibers 0.577719988924391 1.8846056127996944 0.0594831039654502 1.0 0.1677193088807911 16 P07196,Q9H0B6,Q9NR77 3 +Emg chronic denervation signs 0.6274108618946135 1.883351717713602 0.0596527189485296 1.0 0.1680958045143684 12 O60313,P22626,Q9NZJ7,Q969X5,P07602,Q13510 6 +Vacuolated lymphocytes 0.6592830392855962 1.8793638514593851 0.0601948286416278 1.0 0.1686034346438379 4 P04066 1 +Mitochondrial respiratory chain defects 0.7465785668267579 1.877437418192466 0.0604581670923662 1.0 0.1690360998296771 6 O75306,P03886,P00846 3 +Red green dyschromatopsia 0.6065528439317018 1.875229061052552 0.0607612177834919 1.0 0.1690803722414808 3 Q9H6K4 1 +Rigidity 0.4157786808810771 1.8749980777662092 0.0607929879776067 1.0 0.1690803722414808 54 P04062,Q9NZJ7,Q96CU9,Q9BPX6,P07602,P00846,Q9H6K4,Q05639,O43464,Q15392,Q9Y287 11 +Increased csf lactate 0.4295231572925708 1.8743574062041377 0.0608811800709319 1.0 0.1691262631989993 50 P13073,O43464,Q8NI60,P03886,P00846,O95831,O43676,Q86Y39,P00403 9 +Abnormal brainstem mri signal intensity 0.5097369452162391 1.8680181273147056 0.0617595442652805 1.0 0.1712697146175193 23 Q8N183,Q9NPL8,O75489,P03886,Q96CU9,O95831,O43676,O75306,Q86Y39 9 +Increased susceptibility to fractures 0.4151318698211501 1.8679300881192435 0.0617718163498137 1.0 0.1712697146175193 54 P22626,O75718,Q14108,P16435,Q32P28,Q14739,P04062,Q13501,Q14696,O75845,O15269,P51798,O75874,P48735,O60220 15 +Generalized onset seizure 0.3511587790331097 1.865158287639913 0.0621592204057068 1.0 0.1721389112067673 105 Q05086,Q14108,P61978,Q01105,P00846,Q13510,P16278,P07602,Q2M389,Q08J23,P04062,Q71SY5,O75503,Q9Y619,Q9NZJ7,P03886,Q96N66,P00374,Q9H936,O43292,Q9NVI7,Q05639 22 +Abnormal cerebral artery morphology 0.6001664256770878 1.864500940520935 0.0622513896192726 1.0 0.1722917248048557 14 P38435,Q9NSD9,P05067 3 +Delayed cranial suture closure 0.4683348193087648 1.8618732674488592 0.0626209559489361 1.0 0.1732116465618435 32 O75718,Q08J23,Q32P28,P16435,Q8NCH0,P40855,O75844,O75381,Q9Y487 9 +Abnormality of the cerebrospinal fluid 0.3388156020004372 1.861569714800538 0.062663765458655 1.0 0.1732271925854096 145 Q15125,Q96CU9,Q9H9S5,P00846,O43676,P40855,O75306,P00403,P31749,Q9NR77,P16435,P07602,O43505,Q86Y39,P13073,Q08J23,P04062,Q8NI60,Q8WXW3,Q16625,O95831,P08236,O43464,Q15392,Q9NZJ7,O75489,O95202,P03886,P53701,Q10713 30 +Hyperconvex nail 0.7014013263049959 1.8588080160139553 0.0630543558402616 1.0 0.1742035524934393 8 O95202,Q9Y619 2 +Disproportionate short limb short stature 0.5116487757606272 1.8577985470789729 0.0631976275467771 1.0 0.1744956534433192 22 O75718,Q32P28,Q14739,Q15125,Q8WVQ1,Q7LGA3,O00116,Q15392,Q7RTS9 9 +Muscle spasm 0.4045226663116216 1.854595942688699 0.0636539479567555 1.0 0.1755477143768899 59 P07196,P53985,Q9NR77,Q92804,O75298,P04062,Q9H9S5,Q68CQ7,P00846,Q9H6K4,O43464,P35637,P06280 13 +Ascending tubular aorta aneurysm 0.6975328939076667 1.854170005098318 0.0637148418803486 1.0 0.1755893402208205 5 O75844 1 +Follicular thyroid carcinoma 0.6543362720172066 1.8539631359935915 0.0637444341591686 1.0 0.1755893402208205 4 P31749,P21912 2 +Gait disturbance 0.3176911854813828 1.8520342443546844 0.0640209056721081 1.0 0.1761425744953809 333 P07196,Q15907,Q05086,Q14108,P05023,P61978,Q5T8D3,Q96CU9,Q9BPX6,P55795,P01889,O15269,Q9H9S5,P00846,Q9P0J1,Q5XKP0,Q13510,P35637,P16278,Q99720,P00403,O15118,P31749,P22626,Q9NR77,Q9BQT8,Q15041,Q9GZY8,Q8WVQ1,Q8IV08,P05067,P07602,Q4J6C6,P50402,Q9NZ08,O60313,Q15067,P04062,O75298,Q8N3R9,Q96JX3,Q8WXW3,Q7LGA3,Q9Y4P3,O95831,Q96D71,O75844,O75503,O14773,Q71SY5,O43464,O60220,O14949,P98175,Q96BR5,P31483,Q9Y619,Q9NZJ7,Q9H0B6,Q13501,P03886,Q96N66,O43681,Q10713,O43292,Q9H6K4,Q05639,Q9NVI7,Q7RTS9 69 +Ventricular arrhythmia 0.4445995938853225 1.8514896544922632 0.0640991417178271 1.0 0.1762537202607077 44 Q99996,P09493,P42892,P00846,O43772,O75306,P00403,P36551,Q9NX14,P21912,P50402,P0DP25,P13473,P46976,P12235,P49815,Q9BTV4,P03886,P10253,P23786,Q13642 21 +Mediastinal lymphadenopathy 0.6968125823666227 1.8506672996138875 0.0642174312142054 1.0 0.1763707515305241 5 P01889,Q01844,O15460 3 +Glomerular sclerosis 0.4582726330563745 1.8485317261761909 0.0645254591276858 1.0 0.177112309143642 35 O95470,Q14108,P03886,Q8NFH4,P00403,Q14C86 6 +Pili torti 0.5510506066883759 1.8473718660857392 0.0646932637814183 1.0 0.177468329030534 2 P02545 1 +Glomerulopathy 0.6548374572637962 1.8446814224029795 0.0650838948612562 1.0 0.1782250336647451 10 P01889,Q14108,P06280 3 +Epidermoid cyst 0.6517142899377147 1.84047458192542 0.0656985926403972 1.0 0.1794862431196306 4 P25054,P49815 2 +Cutaneous cyst 0.6517142899377147 1.84047458192542 0.0656985926403972 1.0 0.1794862431196306 4 P25054,P49815 2 +Hypopigmentation of the fundus 0.6942692820435514 1.838290455070816 0.0660196168421614 1.0 0.1802575470403211 5 Q9Y619 1 +Hypoglycemic seizures 0.7179127760043063 1.8376405902289352 0.0661153834883685 1.0 0.1803216797687597 7 P53985,Q13423 2 +Abnormality of the nasal bone 0.6508759065908567 1.836157939269967 0.0663343012985464 1.0 0.1807758466891067 4 Q6NUK1 1 +Transient ischemic attack 0.69640191232554 1.8340095363517923 0.0666525785798446 1.0 0.1813479620472642 8 O75844,P06280 2 +Pharyngitis 0.5988939935382729 1.8328309569181005 0.0668277139127799 1.0 0.1815064089829324 3 P01889 1 +Hepatic failure 0.4222193377418576 1.8320558793534891 0.0669430957986729 1.0 0.1817138346329945 51 Q9Y5Y5,O15118,Q9Y619,P04062,P22830,P03886,O75845,P00846,Q10713,P40855,Q13510,O75381 12 +Demyelinating peripheral neuropathy 0.5822593927491282 1.831296479861455 0.0670563027837356 1.0 0.1819151184430056 15 P03886,P00846,Q9NR77 3 +Increased urinary cortisol level 0.5480911512281809 1.8296103975036049 0.0673082178559369 1.0 0.182386084219287 2 P10644 1 +Abnormal urine hormone level 0.5480911512281809 1.8296103975036049 0.0673082178559369 1.0 0.182386084219287 2 P10644 1 +Unusual infection by anatomical site 0.6166356994141828 1.821396295044325 0.0685466379631474 1.0 0.1853509571824257 12 Q14739,P01889,Q9H9P8,Q9BUB7,Q9NZ08 5 +Abnormal cardiac ventricular function 0.503476797164238 1.820399153876957 0.0686982412014629 1.0 0.1856127653807508 23 P12235,P09622,P03886,P10253,Q9H9S5,P22413,P21912,O75844,Q15233,P00403 10 +Lacticaciduria 0.7139379599883986 1.8186103644005815 0.0689708954683749 1.0 0.1862414093285163 7 Q9BQT8,P03886,P00846 3 +Aortic dissection 0.6893955324867655 1.8145320405518253 0.0695958545236601 1.0 0.1871694517154785 5 P22413,P01889 2 +Abnormality of the musculature of the lower limbs 0.4879951587574693 1.812074527959133 0.0699746815852138 1.0 0.1880796692578914 27 P07196,Q9NR77,Q9H9S5,P00846,O14979 5 +Periventricular white matter hyperintensities 0.6903743306174662 1.804033487848319 0.0712260573457044 1.0 0.190672974204765 8 P07602,P17900,O75503,Q9NZJ7 4 +Fetal ultrasound soft marker 0.5039415982508835 1.7998416377771145 0.0718856472351432 1.0 0.1920957639238622 22 Q9Y5Y5,P16435,P61978,Q15125,P22413,P40855,O75381 7 +Abnormality of krebs cycle metabolism 0.686339646104051 1.799608350778768 0.0719225015635929 1.0 0.1920957639238622 5 P00846 1 +Respiratory distress 0.403288922754029 1.7962098741922985 0.0724611449228185 1.0 0.1934235031807958 57 P51571,Q9Y619,P04062,Q9NZJ7,P03886,Q969X5,Q9UHX1,P07602,P00846,P22413,O95831,P10253,O75306,Q13510 14 +Degeneration of the lateral corticospinal tracts 0.7287472281076981 1.7950956289441993 0.07263846508198 1.0 0.1937857791247783 6 P35637,O75298 2 +Cardiovascular calcification 0.6451913382588516 1.7927202996060028 0.0730176589700291 1.0 0.1946858932354868 10 O75844,P04062 2 +Abnormality of retinal pigmentation 0.3704856431480373 1.790007825740536 0.0734526533385087 1.0 0.1957336723402594 76 P51648,Q96CU9,Q9H9S5,P00846,Q8IY17,P40855,O75306,P00403,P31749,Q7Z4L5,Q8N183,Q6P4Q7,Q9Y5Y5,Q9UG56,Q15067,Q15555,P48637,O75489,P03886,P53701,Q96S66,O75381 22 +Pulmonary fibrosis 0.5224239716546984 1.7882632273662364 0.0737335496520954 1.0 0.196145559268681 19 P09601,Q8IZA0,P14174 3 +Dyspnea 0.3459096527590516 1.7844969139123978 0.0743429558288866 1.0 0.1972845602727247 105 P01889,P00846,Q68CQ7,O75306,Q13510,P35637,Q969X5,P07602,P51571,Q92804,P04062,O95831,O75844,Q15165,Q9Y619,Q9NZJ7,Q13501,P03886,Q9UHX1,P10253,P22413,P06280 22 +Diffuse mesangial sclerosis 0.5047845549861361 1.783836283586202 0.0744502718424953 1.0 0.1972845602727247 21 P00813,Q8NFH4,O95470,Q14C86 4 +Abnormal size of the clitoris 0.5073748933024573 1.782319240702084 0.0746971867939876 1.0 0.197468499481495 20 Q9Y5Y5,Q9Y619,P16435,P53701,P51809,P40855,O75381 7 +Corneal ulceration 0.6827492448202346 1.7820480574160809 0.0747413951711162 1.0 0.1974732947856264 5 O75844 1 +Rod cone dystrophy 0.4461040033270231 1.7782010605784513 0.0753708388265963 1.0 0.1986855502287978 40 Q9Y5Y5,Q15555,Q15067,P38435,P03886,P00846,P40855,O75381,Q8N2K0 9 +Generalized myoclonic seizure 0.4458143547915997 1.775477843439517 0.0758190207938418 1.0 0.1997539586299294 40 Q9Y619,P04062,Q9NZJ7,Q96N66,P03886,Q9H936,Q01105,P16278,P07602,P00846,Q9H3H1,Q05639,Q13510,Q8TAB3 14 +Hip pain 0.6807634734633954 1.7723237686983573 0.0763408278872928 1.0 0.2009014555361637 5 O75844 1 +Hyperreflexia 0.3258954937247822 1.7688540359578813 0.0769182364158462 1.0 0.2023066884387419 238 Q05086,Q96CU9,P01889,Q6DKK2,Q9H9S5,P00846,P40855,Q86XL3,O75306,Q5XKP0,P17900,P35637,Q99720,Q9NR77,Q9BQT8,Q15041,Q14739,Q9GZY8,P07602,Q9NZ08,O75208,Q9Y5Y5,O60313,P13073,Q08J23,Q15067,P04062,O75298,Q8NI60,Q9Y4P3,Q3ZCQ8,O95831,Q16625,O75503,O14773,O43464,O60220,O14949,Q8N2K0,Q15555,Q9Y619,Q9NZJ7,Q9H0B6,Q13501,P03886,Q96N66,O75489,Q9H936,O43681,Q10713,O43292,Q9H6K4,Q96IX5,O75381,Q7RTS9 55 +Abnormal csf metabolite level 0.4026064140304211 1.768029937664538 0.0770558989090373 1.0 0.2023143636128094 56 P13073,O43464,Q8NI60,P03886,P00846,O95831,O43676,Q86Y39,P00403 9 +Basal ganglia calcification 0.7033595929010711 1.7677997436806363 0.077094387796867 1.0 0.2023143636128094 7 P03886,P00403 2 +Ventricular hypertrophy 0.4407286985578818 1.767796743561332 0.0770948895261349 1.0 0.2023143636128094 42 P00533,Q9H9S5,O43772,P00403,O75880,Q6NUK1,P21912,Q15233,O75208,O00170,O75844,P46976,P12235,P03886,P10253,P22413,P78536,P23786,Q13642,P06280 20 +Dry hair 0.5374371115714777 1.7654252460808646 0.0774923235027529 1.0 0.2030141973429826 2 Q9Y276 1 +Fatigable weakness of respiratory muscles 0.5709912331952771 1.7606024007733383 0.0783057220157974 1.0 0.204799580656701 15 Q92804,Q13501,Q68CQ7,P35637,Q15165 5 +Atrophy degeneration affecting the central nervous system 0.3179216962431606 1.76023125289592 0.0783686049953611 1.0 0.2048490247297374 311 P07196,P50897,Q6DKK2,Q01105,Q9H9S5,P00846,Q9H9P8,Q68CQ7,P40855,O75306,P17900,Q13510,P35637,P16278,P51572,P00403,Q99720,O15118,P22626,O75880,Q9Y4P3,P05067,P07602,Q2M389,Q86Y39,O75208,Q9Y5Y5,O60313,P13073,Q08J23,Q92804,P04062,O75298,Q8N3R9,Q96JX3,Q7LGA3,Q3ZCQ8,O95831,Q96D71,Q71SY5,O75503,O14773,Q9NSD9,O43464,O60220,Q16625,Q96A33,Q15165,Q9BUB7,P08236,P31483,Q9Y619,Q9NZJ7,Q13501,P03886,Q96N66,P00374,Q9H936,P04066,O75845,Q9UHX1,Q10713,Q05639,Q9UNW9 64 +Ventricular escape rhythm 0.6777476325717974 1.757538936854423 0.0788259911334932 1.0 0.2054680843311759 5 P50402,Q13642,Q9BTV4 3 +Postural instability 0.5037657184981118 1.7556998865238425 0.0791396662078809 1.0 0.206055095134885 20 Q9NR77,P04062,O75503,O43464,O60220 5 +Infectious encephalitis 0.6592829763215557 1.752716173567726 0.0796507381023139 1.0 0.2072699095422225 9 Q14739,Q9NZ08,Q9H9P8,P01889 4 +Positional foot deformity 0.3435713964775615 1.748390526249382 0.080396427247998 1.0 0.2088603224323339 105 P07196,P61978,Q15125,Q9NWM8,Q9NR77,P16435,Q96DF8,Q8WVQ1,Q9Y487,Q8NI60,Q8NCH0,Q15392,Q96A33,P98175,Q9Y619,O95202,O75845,Q9UHX1,Q9NVI7,Q7RTS9 20 +Progressive external ophthalmoplegia 0.63672413320466 1.74690307101468 0.0806541530438584 1.0 0.209296403831918 10 P03886,P00403 2 +Abnormality of corneal size 0.4284163441722481 1.74304487869588 0.0813257758421137 1.0 0.2107090946741577 46 Q9NWM8,Q15125,O95202,Q8NCH0,O75845,Q9H9S5,O43505,Q9Y4P3,Q71SY5,Q96EK5 10 +Unexplained fevers 0.717535031411645 1.742996344368018 0.0813342533757268 1.0 0.2107090946741577 6 P07602,Q9HC07 2 +Weakness of muscles of respiration 0.4494690718117099 1.7416765627019652 0.0815650558451159 1.0 0.2109972905016207 33 P22626,Q15067,P36551,P10253,O95831,P50402,Q13510,Q7RTS9 8 +Dysarthria 0.3321804529810312 1.7415832682827377 0.0815813911965261 1.0 0.2109972905016207 157 P07196,P51648,Q14108,Q96CU9,Q6DKK2,P15586,P00846,O75306,Q5XKP0,P35637,O15118,Q8IV08,P07602,P61916,Q9Y5Y5,Q08J23,P04062,Q9Y4P3,Q96D71,O75503,O14773,O60220,Q8N2K0,P48637,Q9NZJ7,Q9H0B6,O75489,Q13501,Q10713,O43292,Q9H6K4,Q96BR5 32 +Sunken cheeks 0.5327019828351656 1.7367788519166805 0.0824262132900088 1.0 0.2123569145491489 2 P17980 1 +Hyperkeratotic papule 0.5327019828351656 1.7367788519166805 0.0824262132900088 1.0 0.2123569145491489 2 Q9H488 1 +Increased connective tissue 0.6768426374960711 1.736435997714862 0.0824867718767579 1.0 0.2123954579336309 8 P07196,O95831 2 +Neck flexor weakness 0.6314621331933734 1.7357164705937835 0.0826139797525202 1.0 0.2126054793852151 4 P35637,Q99720 2 +Leukoencephalopathy 0.3423695015215205 1.734477247983919 0.082833439263422 1.0 0.213052545604097 97 Q96CU9,Q01105,Q9H9S5,Q9H9P8,O43676,O75306,P17900,P07602,Q86Y39,O60313,P51571,O95831,O75503,Q9BUB7,Q96BR5,O00584,Q9NZJ7,O75489,O95202,P03886,Q9UHX1,Q05639 22 +Arthropathy 0.672459906761341 1.7315694961014574 0.0833502412837259 1.0 0.2140272458101407 5 O15269 1 +Arm dystonia 0.5805072389978514 1.7303582259177517 0.0835662925345621 1.0 0.214463796488149 3 P35637 1 +Blindness 0.3728201038953766 1.7277793877819676 0.084027784189268 1.0 0.2154107973327521 84 P50897,Q15058,Q96CU9,P01889,Q9H9S5,P00846,O43676,O75306,P17900,P16278,P31749,Q8N183,Q9NX14,P07602,P51798,O43505,Q86Y39,Q9NZ08,Q9NPL8,Q15555,Q9NZJ7,O75489,P03886,P53701,P06865,Q9H6K4 26 +Chorea 0.3707968746612859 1.725636446517643 0.0844128381560298 1.0 0.216159978081796 85 Q9BWD1,Q9BPX6,Q01105,P00846,O75306,Q5XKP0,P17900,P35637,Q99720,P07602,Q2M389,Q08J23,Q71SY5,Q9NZJ7,P03886,Q96N66,Q9H936,O43681,Q9H6K4,Q05639 20 +Hallucinations 0.423849442694426 1.724129842132685 0.0846844058792601 1.0 0.2164983329229385 47 O60313,P50897,P36551,P04062,Q9NZJ7,Q13501,Q6DKK2,P05067,P07602,Q9BQE5,O75503,O43464,P35637 13 +Infantile spasms 0.4442161021551727 1.7211062609582377 0.08523154338269 1.0 0.2177775804040428 35 P00846,Q13510,Q9UBX3 3 +Enlarged ovaries 0.6697986208847443 1.718476879741282 0.0857096680493239 1.0 0.2187592513828771 5 P31749,P16435 2 +Nocturnal seizures 0.5294465818289504 1.7170428920415828 0.0859713353220361 1.0 0.2193069441018863 2 Q01082 1 +Abnormal placenta morphology 0.6723108606180598 1.7137062311943292 0.0865826919357219 1.0 0.2204335013987991 8 O75844 1 +Abnormality of skull ossification 0.6086434886326552 1.713085000502235 0.0866969030834263 1.0 0.2204335013987991 11 P54802,O75718,Q32P28,O75844 4 +Upper airway obstruction 0.6683928625480369 1.7115550651556934 0.0869786952058846 1.0 0.2209269183688327 5 Q96HY6,O75844 2 +Optic neuropathy 0.4825778520697521 1.7101097543084245 0.087245579376034 1.0 0.2214658903180199 25 Q8N183,Q9NPL8,O75489,P03886,Q96CU9,P00846,O43676,O75306,Q86Y39 9 +Abnormal glomerular mesangium morphology 0.4919436984271687 1.7089836031589094 0.0874539867850312 1.0 0.2217298646010366 22 P00813,Q8NFH4,O95470,Q14C86 4 +Spondyloepimetaphyseal dysplasia 0.7099140221900822 1.7074464068586477 0.0877391110311067 1.0 0.2222342464289806 6 O95831,Q7RTS9 2 +Pace of progression 0.32998075471901 1.702526075863485 0.0886567945789225 1.0 0.2240712692070651 163 P07196,O60762,P05023,Q14108,P15586,Q8IY17,Q5XKP0,Q13510,Q99720,P31749,Q9NR77,Q8N183,P27544,Q9GZY8,Q8IV08,Q86U42,P50402,O75569,P54802,Q9Y5Y5,O60313,P04062,O75298,Q13126,O95831,Q96D71,O14773,P28288,P49736,Q8N2K0,P46976,P12235,O95470,O00584,Q9NR28,Q9NQZ5,P31483,Q9BTV4,Q9H0B6,Q13501,Q03252,Q9Y4W6,Q10713,Q8N1F7,Q96BR5,O14979,P20700,P07942 48 +Meningitis 0.6664967703008831 1.702212414736224 0.0887155563400303 1.0 0.224098189496671 5 Q9NZ08,P01889 2 +Abnormal sella turcica morphology 0.6696376895508108 1.700277583536507 0.089078724884249 1.0 0.2245285175924416 8 P16278,Q7RTS9 2 +Talipes calcaneovalgus 0.6659316343695802 1.6994263777703555 0.0892388754196291 1.0 0.2248105363464752 5 Q9NR77 1 +Hepatic cysts 0.6238149394299555 1.6959049274040163 0.0899038863687993 1.0 0.2263634068680363 4 Q7Z4L5,Q9UGP8 2 +Intellectual disability progressive 0.5839154487238012 1.6955187840877557 0.0899770499590557 1.0 0.2264252289083099 13 O95721,Q15067,P53701,Q9H9P8,O95831 5 +Arterial thrombosis 0.6874384314101961 1.6908883048955283 0.0908581373645336 1.0 0.228004455496809 7 P31749,Q9NZ08,P01889 3 +Abnormality of hand joint mobility 0.5733922310145676 1.690455131575973 0.0909409152677565 1.0 0.228004455496809 3 P48651 1 +Hyperextensibility of the finger joints 0.5733922310145676 1.690455131575973 0.0909409152677565 1.0 0.228004455496809 3 P48651 1 +Reduced tendon reflexes 0.3289737445734977 1.6887728038450205 0.0912629775189941 1.0 0.2285499727330509 174 P07196,P05023,P61978,O15269,Q9H9S5,P00846,P40855,Q13510,P35637,Q99720,O95721,Q9NR77,Q9BQT8,Q15041,Q969X5,P07602,O43505,P50402,P54802,Q9Y5Y5,O60313,Q15067,P04062,O95831,Q71SY5,Q8N2K0,Q96BR5,Q9NZJ7,Q9H0B6,Q13501,P03886,P10253,O43681,Q10713,Q9H6K4,Q05639,O14979,O75381 38 +Type 1 muscle fiber atrophy 0.6867232714519149 1.687421551085618 0.0915223227620549 1.0 0.2289889863283409 7 Q9BTV4,P61978,P06753,P50402,Q13642 5 +Desquamation of skin soon after birth 0.6221745027736523 1.6873472416885436 0.0915366020917498 1.0 0.2289889863283409 4 P00813 1 +Poor head control 0.3646847628990433 1.6856222659744915 0.091868577772044 1.0 0.2294497776204724 79 Q9NWM8,P13073,O95721,Q9NZJ7,Q86Y39,O75489,P03886,Q96CU9,P00374,P07602,Q10713,P06865,O43676,Q05639,O75306,Q5XKP0,P17900 17 +Focal t2 hyperintense brainstem lesion 0.4937204941100459 1.6812694731571136 0.092710584531757 1.0 0.231304714916403 20 Q8N183,Q9NPL8,O75489,P03886,Q96CU9,O43676,O75306,Q86Y39 8 +St segment elevation 0.6208760700994798 1.6805693745365495 0.0928465886058078 1.0 0.2313961528763258 4 P46976 1 +Abnormal st segment 0.6208760700994798 1.6805693745365495 0.0928465886058078 1.0 0.2313961528763258 4 P46976 1 +Proximal muscle weakness 0.3743733916092069 1.6791037522391592 0.0931318250822719 1.0 0.2317350647613368 66 P07196,Q8TD16,Q5T8D3,Q9BPX6,Q9H9S5,P00846,Q13510,P35637,Q99720,P22626,P36551,Q9BQT8,Q86U42,P21912,P50402,O60313,O75340,Q8NI60,Q13126,P06753,P13473,P12235,Q7Z406,P09651,Q9BTV4,Q13501,P10253 27 +Apneic episodes precipitated by illness fatigue stress 0.5229357798165208 1.677471831861827 0.0934502531614329 1.0 0.2322667514180317 2 P53007 1 +Hypertrophic cardiomyopathy 0.3386500775953075 1.677455704742367 0.0934534043149881 1.0 0.2322667514180317 111 P09493,Q96CU9,P01889,P15586,P00846,O43676,O75306,Q5XKP0,P16278,Q9H061,P00403,P50402,Q86Y39,P54802,O60313,P50416,Q9NPL8,Q9Y4P3,Q9BUB7,Q8N5M1,P13473,O75489,P03886,P10253,P53701,Q13423,Q9NVI7,Q96IX5,P06280 29 +Abnormality of the alveolar ridges 0.6650592817344282 1.677242372255391 0.0934950963737246 1.0 0.2322667514180317 8 Q15392,P53634,P98175 3 +Abnormality of peripheral nerves 0.4136132043824407 1.676741730229264 0.0935929965963267 1.0 0.2323276324347881 49 P07196,O95721,Q9NR77,Q9Y619,Q9NZJ7,Q9GZY8,O15269,P07602,O95831,Q71SY5,Q99720,Q8N2K0 12 +Wide cranial sutures 0.6648825226442596 1.676352156447888 0.0936692343736651 1.0 0.2323276324347881 8 O75844,P98175 2 +Glomerular deposits 0.5223438887244818 1.6738680324304367 0.0941565380849236 1.0 0.2325456810178018 2 P57740 1 +Type i diabetes mellitus 0.6016765561657336 1.673460524849954 0.0942366714360423 1.0 0.2326202520132936 11 P00403 1 +Abnormality of endocrine pancreas physiology 0.619327017076672 1.6724783046928366 0.0944300424825699 1.0 0.232799042416426 4 P53985 1 +Proximal tubulopathy 0.4743738599798713 1.6723168307756324 0.094461862496582 1.0 0.232799042416426 26 Q8N183,Q9NPL8,O75489,P03886,Q96CU9,O43676,O75306,Q86Y39,P00403 9 +Hyporeflexia 0.3362899033085857 1.672295234425592 0.094466118920002 1.0 0.232799042416426 122 P07196,O15269,Q9H9S5,P00846,P35637,Q9NR77,P07602,O43505,P54802,Q15067,P04062,O95831,Q71SY5,Q8N2K0,Q96BR5,Q9NZJ7,Q9H0B6,P03886,Q10713,Q05639,O14979 21 +Nyctalopia 0.4568037126214651 1.670480975655202 0.0948242403313728 1.0 0.2333114611110223 30 Q9Y5Y5,Q15555,P38435,Q10713,O75381,Q96S66,P40855,Q9Y287 8 +Macrodontia of permanent maxillary central incisor 0.521751997632443 1.6702631774531704 0.0948673051404624 1.0 0.2333114611110223 2 P49711 1 +Anterior open bite malocclusion 0.5217519976324428 1.6702631774531682 0.0948673051404629 1.0 0.2333114611110223 2 P08754 1 +Abnormal caudate nucleus morphology 0.6004962870240931 1.6667345350933849 0.0955672025954756 1.0 0.234811799372119 11 P00846,O60220 2 +Motor seizure 0.3382536379340695 1.6666793459805127 0.0955781819685568 1.0 0.234811799372119 107 Q01105,P00846,Q5XKP0,P16278,Q13510,Q9UBX3,Q9GZY8,P07602,Q2M389,P13073,Q08J23,P04062,Q71SY5,O75503,Q9Y619,Q9NZJ7,P03886,Q96N66,Q9H936,O43292,Q05639 21 +Severe global developmental delay 0.3585776425961081 1.6618550803240453 0.096541835181058 1.0 0.2368045646515895 73 Q9Y5Y5,O00584,Q15067,P03886,Q8N3R9,P00846,Q7LGA3,P22413,P40855,Q71SY5,Q96A33,Q7RTS9 12 +Microcytic anemia 0.6616015067710144 1.6598159872948022 0.0969514765271644 1.0 0.2374002534162456 8 P22830,Q9UBX3 2 +Osteopenia 0.35841019200734 1.659631767533098 0.0969885535103296 1.0 0.2374002534162456 73 Q9NWM8,O75718,Q14108,Q32P28,P04062,Q9NZJ7,P07602,O43292,O75844,Q9NSD9,Q9Y487 11 +Sepsis 0.4875790602849039 1.654774409266454 0.0979702668280662 1.0 0.239174791868518 21 P00813,P01889,P42892,Q96JX3 4 +Hypersplenism 0.6402331669303614 1.6531854569213702 0.0982931253439645 1.0 0.2394609716800139 9 P07602,Q14108 2 +Abnormality of bone mineral density 0.3289831355222259 1.6529052547003011 0.0983501475481696 1.0 0.2394746405015024 138 Q13277,Q14108,P61978,Q15125,P48651,Q96HY6,Q13510,P16278,Q9NWM8,O75718,Q14739,Q8WVQ1,P07602,P51798,P54802,Q9Y487,Q32P28,P04062,Q9Y4P3,O95831,O75844,Q9NSD9,Q15392,Q9NZJ7,O95202,Q13501,O75845,Q9HC07,P22413,O43292,P06280 31 +Abnormality of the mitochondrion 0.3371464295446675 1.6500389907922044 0.0989349615429737 1.0 0.2406974788830256 101 Q96CU9,P20674,Q9Y2R0,Q9P0J1,P00846,O43676,O43772,O75306,P35637,P00403,Q70HW3,Q8N183,O75880,Q9NX14,Q9UBX3,Q9GZY8,Q4J6C6,Q86Y39,O95298,P13073,Q9NPL8,Q3ZCQ8,Q9BUB7,P46976,P12235,P09622,O75489,Q13501,P03886,O75648,Q9Y4W6 31 +Foam cells 0.6789521343783219 1.649686466416984 0.0990070796329543 1.0 0.2406974788830256 7 O15118,P61916,Q13510,O75845 4 +Progressive spastic quadriplegia 0.6589897136021743 1.646636652603387 0.0996327520085709 1.0 0.2418391656362289 8 P07602,P17900,Q9NZJ7 3 +Generalized joint laxity 0.5644982399560347 1.646183620577159 0.0997259604521667 1.0 0.2419033328307354 14 Q8NCH0,Q9Y487 2 +Abnormality of humoral immunity 0.3981244378021071 1.643316548815857 0.1003174560887423 1.0 0.2428391183282812 53 P09601,P00813,P14174,Q14108 4 +Abnormal corpus striatum morphology 0.5275810508273658 1.6397668524020006 0.1010536527760705 1.0 0.2441431092484112 17 P00846,O60220,O95831 3 +Paranoia 0.6768018388929613 1.6392245774825018 0.101166497039995 1.0 0.2441624576229517 7 Q96DF8,O60220 2 +Abnormality of metacarpal epiphyses 0.6533770571754781 1.6373682241692464 0.1015535535095897 1.0 0.2449696800868301 5 O95202 1 +Left ventricular systolic dysfunction 0.6761939455862666 1.6362653945359396 0.1017840553042888 1.0 0.2453986178092014 7 P12235,P22413,O75844 3 +Proximal amyotrophy 0.5509050355441468 1.6334599161238956 0.1023723044676354 1.0 0.2466891847957816 15 P07196,O14979,P35637,Q9H9S5 4 +Oligosacchariduria 0.693995462366938 1.632845815760111 0.1025014284318075 1.0 0.2468726233895344 6 P10253,P04066 2 +Wormian bones 0.5001578937864144 1.6287460159004554 0.1033667970694369 1.0 0.2484430034826818 19 O75718,O95831,O75844,Q9Y487 4 +Abducens palsy 0.6513865002584517 1.6275002842511868 0.1036308882870087 1.0 0.2488209678561271 5 P07602 1 +Hypoplasia of the odontoid process 0.6922203980387793 1.6244992824778968 0.1042692933984894 1.0 0.2500959673790751 6 P16278,O95831,Q7RTS9 3 +Abnormality of alkaline phosphatase level 0.4716512923546185 1.6233107838163665 0.1045229854474976 1.0 0.250446536118541 25 P22626,Q8N511,Q14739,Q13501,O75845,P51798,P22413,Q96A33 8 +Stroke like episode 0.6915085899761534 1.6211507620161267 0.1049853095739874 1.0 0.2512391921886185 6 P00403 1 +Heterochromia iridis 0.5608204528663052 1.6196277844380422 0.1053122574431459 1.0 0.2515612795744482 3 P31749 1 +Nasal regurgitation 0.5603907637655549 1.617200015111306 0.1058351130877031 1.0 0.2525512073578488 3 P53007,Q13472 2 +Abnormality of the anterior fontanelle 0.4306877924553308 1.6150003562220994 0.1063106177296611 1.0 0.2533044071255945 39 Q9Y5Y5,O75718,Q08J23,Q32P28,P16435,Q9Y619,Q15125,P40855,O75381,Q9Y487 10 +Prominent nasolabial fold 0.6900804016473127 1.6144295946190206 0.1064342767643564 1.0 0.2533320700911458 6 Q9Y487 1 +Abnormality of the nasolabial region 0.6900804016473127 1.6144295946190206 0.1064342767643564 1.0 0.2533320700911458 6 Q9Y487 1 +Broad ribs 0.6475054899632369 1.608238950492786 0.1077828555250279 1.0 0.2560056142064487 5 P16278,Q7RTS9 2 +Cupped ribs 0.6875120175901017 1.602333857644672 0.1090818024677582 1.0 0.2585766085978716 6 P00813 1 +Finger swelling 0.510506066883701 1.6015757781357935 0.1092494506011179 1.0 0.2587106969496742 2 P28070 1 +Hyperaldosteronism 0.5105060668837008 1.6015757781357916 0.1092494506011183 1.0 0.2587106969496742 2 P04637 1 +Impaired temperature sensation 0.6460550084602414 1.601032992416573 0.1093696119504663 1.0 0.2588636445453619 5 Q9NR77 1 +Babinski sign 0.3632446041678085 1.5990321919470074 0.1098134498363214 1.0 0.2596502788515661 84 P07196,O60313,Q9NR77,Q15067,O75298,Q9NZJ7,Q13501,Q6DKK2,O60220,P07602,P00846,O95831,Q9H6K4,O14773,P35637,Q99720,Q8N2K0 17 +Tracheal stenosis 0.6864716864498396 1.5974312862577142 0.1101696031417169 1.0 0.2603021687052133 6 Q15125 1 +Exercise intolerance 0.4321212424220121 1.5972907213250764 0.1102009181379735 1.0 0.2603021687052133 34 Q9H2D1,Q8NI60,P03886,Q9Y2R0,P00403 5 +Osteolysis 0.4426512404198619 1.5924434590346055 0.1112850978879114 1.0 0.2625967507405731 31 P22626,Q14108,P04062,Q13501,O75874,P48735,O75844 7 +Genu varum 0.5551860781106973 1.5884994345474452 0.1121734488137069 1.0 0.2644250630436472 14 Q7RTS9,P22413,Q96HY6,Q9Y619 4 +Aplasia hypoplasia involving the skeletal musculature 0.6062867027250348 1.580693522242686 0.1139481302211984 1.0 0.267660307902341 10 Q9H9S5,Q9NR77,Q9Y487 3 +Abnormality of carpal bone ossification 0.6819881794879322 1.5762821916050636 0.1149607838852095 1.0 0.2688538838659257 6 Q15125,P22413 2 +Positive romberg sign 0.6450437732145098 1.57603164644691 0.1150185101641585 1.0 0.2688538838659257 8 Q9H6K4,Q8IV08 2 +Abnormal gastrointestinal motility 0.4624431070523961 1.575852138447653 0.1150598833090488 1.0 0.2688538838659257 26 P06280,P61978,P03886,Q01844,P35637,P00403 6 +Abnormal involuntary eye movements 0.3111143501068375 1.5738816392446648 0.1155148154286824 1.0 0.2693373953090295 299 P07196,Q15907,Q13277,Q05086,Q15125,Q5T8D3,Q96CU9,P01889,Q6DKK2,Q9P0J1,P00846,Q9BT22,Q9H9P8,O43676,P40855,O75306,Q5XKP0,Q13510,P17900,P35637,Q9H061,Q99720,P78318,Q9NR77,Q6P4Q7,Q8IV08,P07602,Q86Y39,Q9Y5Y5,O60313,Q08J23,Q15067,P04062,Q8N3R9,Q86YV9,Q8WXW3,Q7LGA3,Q9Y4P3,O95831,Q96D71,Q16625,O75503,O14773,Q15392,Q8N2K0,Q15555,O00584,O15460,Q9NZJ7,Q9H0B6,O95202,P03886,Q13501,O75489,Q10713,O43292,Q9H6K4,Q05639,Q9NVI7,O75381 60 +Orthostatic hypotension due to autonomic dysfunction 0.6249863212682548 1.572935171892015 0.1157338299805341 1.0 0.2696789294894087 9 P07602,Q9NZJ7,P04062 3 +Retinal coloboma 0.6248187290657804 1.572050322302575 0.1159388811695927 1.0 0.269846192075676 9 Q9UHX1,Q10713,Q8N201 3 +Mesoaxial polydactyly 0.5995977050915192 1.568974704556044 0.1166538332365276 1.0 0.2710092544716937 4 O43924 1 +Sick sinus syndrome 0.551805802249866 1.5686024954454858 0.116740590629913 1.0 0.271075608750815 3 Q99996,Q14BN4 2 +Shoulder girdle muscle weakness 0.5627487757411715 1.5680912805571343 0.1168598311594406 1.0 0.2712172862683978 13 P46976,P12235,Q8TD16,Q9NZJ7,Q9H9S5,P07602,O14979 7 +Serositis 0.4730682833594329 1.5645448383791227 0.1176896716098001 1.0 0.2730072163139687 22 P01889,Q8N1F7,Q8NFH4,Q9NZ08,P14174,Q14C86 6 +Kinetic tremor 0.4278233072405944 1.557948600253221 0.1192454330528069 1.0 0.2762034943610019 34 P31749,P48637,Q14108,Q9NZJ7,P07602,O43681,Q8IY17,Q9Y4W6,Q9BUB7,Q15233,Q9Y287,Q8N2K0 12 +Agitation 0.4276030917819327 1.5559293393443292 0.1197248958229399 1.0 0.2768881588657132 34 Q92804,P04062,P42892,P05067,Q68CQ7,O43464,P35637 7 +Abnormal conjunctiva morphology 0.4599814204154202 1.5558504426760011 0.1197436600261783 1.0 0.2768881588657132 26 P10619,P31749,Q14739,P01889,P04066,Q13510,P06280 7 +Noncompaction cardiomyopathy 0.5494474590058234 1.555222666469212 0.1198930477991857 1.0 0.2768881588657132 3 Q15233 1 +Fatigable weakness of bulbar muscles 0.5270672893096092 1.5551734289164527 0.1199047707058647 1.0 0.2768881588657132 16 Q92804,Q13501,Q68CQ7,P35637,Q15165 5 +Progressive hearing impairment 0.549790032769219 1.5549535661511442 0.1199571285081599 1.0 0.2768881588657132 14 O60313,P03886,Q9NSE4,O76024,O60220,P49736,P00403 7 +Rhizomelia 0.560396648279463 1.553851605174858 0.1202198177115501 1.0 0.2772197578714853 13 O75718,Q14739,Q15125,Q15392,Q7RTS9 5 +Retinal vascular tortuosity 0.514721816130022 1.5526030916719396 0.1205179866001171 1.0 0.2776324340174805 17 O00192,Q96DF8,P03886,Q9Y4P3,P00846,P54198,O75306 7 +Distal amyotrophy 0.370639888784321 1.551885102371819 0.1206897181456705 1.0 0.2778906115286867 63 P07196,P31483,Q9NR77,Q9BQT8,Q9H0B6,O15269,Q71SY5,Q9NVI7,Q13510,P35637,Q96BR5,Q99720,Q8N2K0 13 +Bruising susceptibility 0.4379544470808763 1.5511981269101176 0.1208542109057535 1.0 0.2781318747030632 31 Q9NWM8,Q14108,P04062,P38435,Q8NCH0,Q86YV9,P51798,P22413,P49257 9 +Abnormal activity of mitochondrial respiratory chain 0.3799205872320064 1.5492201892830235 0.1213287977564419 1.0 0.2790861925676575 58 O95298,Q70HW3,P13073,O75489,Q9UBX3,Q96CU9,P03886,P20674,Q9Y2R0,Q3ZCQ8,O43676,O75306,Q86Y39 13 +Lung adenocarcinoma 0.5482534043812971 1.5484435829908816 0.1215155349219605 1.0 0.2792399416213577 3 P30154,P00533 2 +Retinopathy 0.4586352538838402 1.5448987933991936 0.1223707453708664 1.0 0.2809280098262671 26 P51648,O95202,P01889,P00846,P22413,O75306,Q9NZ08 7 +Abnormal autonomic nervous system physiology 0.4259700087720039 1.5409443920640784 0.1233303204166873 1.0 0.282852108567666 34 P06280,Q15067,P04062,Q9NZJ7,P42892,P07602,O43464,P0DP25 8 +Pulmonary infiltrates 0.6376978175401653 1.5386902243056158 0.1238799400071228 1.0 0.2838331335726406 8 Q13510,P01889,P04062 3 +Parkinsonism with favorable response to dopaminergic medication 0.5982784647238361 1.5365984249335916 0.1243916785211014 1.0 0.2844459688518854 10 P07602,O43464,P04062 3 +Schizophrenia 0.4692806627900128 1.5353521149286826 0.1246973592503799 1.0 0.2848652767966012 22 P16615,O00192,P04062,Q9NZJ7,P07602,O43681,P54198,Q9BQE5,O76024 9 +Coxa valga 0.4738547813939206 1.5326599965205618 0.1253596505186598 1.0 0.2857458570336822 20 Q9Y619,P04066,P22413,O75844,P16278,Q96A33 6 +Delayed eruption of primary teeth 0.4992601361349583 1.5325387143967442 0.125389551691033 1.0 0.2857458570336822 2 Q8NC56 1 +Corticospinal tract hypoplasia 0.4992601361349563 1.5325387143967315 0.1253895516910361 1.0 0.2857458570336822 2 P11177 1 +Bilateral tonic clonic seizure with generalized onset 0.6170911679513871 1.5311887782426792 0.125722743410348 1.0 0.2860852656596977 9 Q13510,Q05086,P04062 3 +Central apnea 0.6545790848889093 1.530611492660772 0.1258654396453835 1.0 0.2862701259122053 7 P07602,Q10713 2 +Eyelid myoclonus 0.5967200878172005 1.5280013880899963 0.1265121933169766 1.0 0.2871802127049108 10 Q13510,P00374,Q05639 3 +Kyphosis 0.3203066285732088 1.5272180502679802 0.1267067993172335 1.0 0.2874818661566846 159 P51648,Q14108,Q15125,P01889,P48651,Q9H9S5,P16278,Q9NWM8,P31749,Q9NR77,Q14739,Q8WVQ1,P50402,Q9Y487,Q32P28,P04062,Q8N3R9,Q8NCH0,Q7LGA3,Q9Y4P3,O95831,O75844,Q71SY5,P08236,O75489,Q9H0B6,O95202,P04066,Q9UHX1,Q9HC07,Q7RTS9 31 +Psychosis 0.4255228515107986 1.5254250817800163 0.1271531067217626 1.0 0.2880735268044602 33 O15118,P48637,P36551,Q13501,P03886,Q6DKK2,P61916,Q9Y287,P00403 9 +Atrophy degeneration affecting the cerebrum 0.3115411648735463 1.5233588986203437 0.1276689390219032 1.0 0.2891015643967065 250 P50897,Q6DKK2,Q01105,Q9H9S5,P00846,Q9H9P8,P40855,P17900,P16278,P51572,P00403,Q9Y4P3,P05067,P07602,Q2M389,O75208,Q9Y5Y5,O60313,P13073,Q08J23,P04062,Q8N3R9,Q7LGA3,Q3ZCQ8,O95831,Q96D71,Q71SY5,O75503,O14773,Q9NSD9,O43464,O60220,Q16625,Q96A33,Q9BUB7,Q9Y619,Q9NZJ7,Q13501,P03886,Q96N66,P00374,Q9H936,P04066,O75845,Q9UHX1,Q10713,Q05639,Q9UNW9 48 +Abnormal waist to hip ratio 0.6522803160723012 1.5193278203432203 0.1286800003826915 1.0 0.2906845013494555 7 Q9Y6M1,O76024,P31751,P22413,P18031 5 +Submucous cleft of soft and hard palate 0.4519261951883085 1.5173583810775344 0.1291762257122792 1.0 0.2913618645206511 27 Q08J23,Q9Y619,Q96DF8,Q9H9S5,Q7LGA3,O43505,O75844,Q15392 8 +Disproportionate short trunk short stature 0.6292073142007569 1.5170579488086129 0.1292520539443704 1.0 0.2913618645206511 5 Q9UHX1,Q7RTS9 2 +Abnormal nerve conduction velocity 0.4083398307334523 1.5158196118505372 0.1295649715886939 1.0 0.2918344476112846 45 P07196,Q9NR77,Q9Y619,Q9NZJ7,Q9GZY8,O15269,P07602,O95831,Q71SY5,Q99720,Q8N2K0 11 +Ecchymosis 0.5630861894454949 1.5083490949042724 0.1314652041750432 1.0 0.2954634127036676 12 Q8NCH0,P04062 2 +Pedal edema 0.6316730026924071 1.5079915019125274 0.1315567020067425 1.0 0.2954634127036676 8 Q14108 1 +Headache 0.3487728464368607 1.507418044751217 0.1317035363536958 1.0 0.2955829123215435 71 O60313,P31749,Q14C86,P04062,P03886,P01889,P05067,P00846,Q8N1F7,Q9NSD9,Q8NFH4,Q9NZ08,Q9NQZ5,P00403 14 +Centrally nucleated skeletal muscle fibers 0.6668702175880492 1.5047344486250904 0.1323923627053067 1.0 0.2966951605307937 6 Q9BPX6 1 +Intrinsic hand muscle atrophy 0.6266333347120877 1.504185760005149 0.1325335432689423 1.0 0.2967986752628525 5 P31483,Q9NR77 2 +Cogwheel rigidity 0.6663359465231717 1.502199619734039 0.1330455630171552 1.0 0.2975161942073495 6 P00846,Q8TAB3 2 +Impaired visuospatial constructive cognition 0.6482889098361058 1.4997155418621593 0.1336881029272723 1.0 0.2986662750288893 7 P03886,P00403 2 +Coarse hair 0.4946766328122899 1.4984409070029163 0.134018734936385 1.0 0.2989747448916099 18 P15586,P54802,Q9Y487 3 +Neoplasm of the adrenal cortex 0.6476134682305408 1.4963941896134672 0.1345509628052004 1.0 0.2996257109639697 7 P48735 1 +Congenital hepatic fibrosis 0.5855426313718106 1.4947654074692105 0.1349756773062456 1.0 0.3003902077842771 4 Q10713,Q8IY17 2 +Slow decrease in visual acuity 0.6101496139072867 1.4943840799567594 0.1350752602040605 1.0 0.3004539153710837 9 O75306,P03886,P00846 3 +Abnormal abdomen morphology 0.3143234974178801 1.49413337328645 0.1351407626635301 1.0 0.3004539153710837 224 P10619,P00813,Q14108,Q96CU9,P01889,P15586,P00846,Q96HY6,O43676,P40855,O75306,Q13510,P16278,O15118,P31749,O75880,P36551,P09601,Q14739,P07602,P61916,Q86Y39,Q9NZ08,P14174,P54802,Q9Y5Y5,Q15067,P04062,P31751,Q16625,Q9NSD9,Q9BUB7,P08236,Q8N5M1,P33991,Q15392,Q96A33,Q9Y619,Q9NZJ7,P03886,P00374,P04066,O75845,P10253,Q9HC07,Q10713,P22413,Q01844,Q9NVI7,O75381 50 +Paralysis 0.3962367389231572 1.493915098296647 0.1351978116397147 1.0 0.3004539153710837 49 Q02978,Q9NR77,Q92804,P36551,P04062,Q9BTV4,Q13501,P50995,P10253,P51798,Q68CQ7,P50402,Q15233,P17900,P35637,Q15165 16 +Cachexia 0.493933230399494 1.4931988883063565 0.1353851330352005 1.0 0.3007267285064205 18 Q9NZJ7,P04062,P07602,Q01844,P35637,Q99720 6 +Resting tremor 0.4936893735667272 1.4914789321009652 0.135835798452043 1.0 0.3013389313743333 18 P07602,Q9BPX6,Q9H6K4,P04062 4 +Abnormal astrocyte morphology 0.4811197454555064 1.4906429293814678 0.1360552670585311 1.0 0.3014913416376525 19 P00846,O95831,P48735 3 +Hyperorality 0.6238800709011931 1.4904052625812796 0.1361177096315979 1.0 0.3014913416376525 5 Q13501 1 +Abnormality of the ribs 0.3522642426775403 1.4887103312480403 0.1365636633096245 1.0 0.3022993361273663 69 P00813,O75718,Q7RTS9,Q32P28,P16435,Q9Y619,O95202,P15586,Q9UHX1,Q96HY6,O95831,O75844,P16278,P54802 14 +Abnormal pupil morphology 0.5597390803705531 1.4885257293244458 0.1366123019639558 1.0 0.3022993361273663 12 Q9NR77 1 +Abnormal saccadic eye movements 0.4546397199832224 1.4868982006440206 0.1370416995793966 1.0 0.3027131118674442 25 O14773,Q10713,P04062,Q8IV08 4 +Bell shaped thorax 0.5374256573997819 1.4868317910005042 0.1370592427927093 1.0 0.3027131118674442 3 Q96HY6 1 +Abnormal renal tubule morphology 0.4545959165450438 1.486545051745648 0.1371350096307095 1.0 0.3027369075165143 25 O75306,P00846,P03886,P06280 4 +Pigmentary retinopathy 0.4006655005255358 1.4861413476978649 0.1372417375362051 1.0 0.3028289973679032 47 Q9UG56,Q15555,P48637,Q15067,O75489,P03886,Q96CU9,Q9H9S5,P00846,Q96S66,O75306,P00403 12 +Distal upper limb amyotrophy 0.5382804609457362 1.4831237869112168 0.1380415251996394 1.0 0.3043054540368766 14 P07196,Q9BQT8,P31483,Q9NR77 4 +Neurodegeneration 0.4435991739335987 1.4766831928752202 0.1397605794963179 1.0 0.3073807142568046 28 Q92804,Q13501,Q6DKK2,Q68CQ7,P08236,P17900,P35637,Q15165 8 +Abnormality of the lymph nodes 0.417694173814309 1.476661120192863 0.1397664990974478 1.0 0.3073807142568046 35 P00813,O15460,P01889,P51798,Q01844,Q13510,P33991,Q9NZ08,P14174 9 +Diarrhea 0.3452898507644572 1.473606481923552 0.1405875751157852 1.0 0.3088947758911923 74 P00813,Q13277,P01889,P42892,P15586,Q9BT22,Q13510,P00403,P36551,P54802,P50416,Q08J23,Q14566,O43464,Q96A33,P03886,Q13423,P78536,P06280 19 +Abnormal larynx morphology 0.4290380547815487 1.4725163874395095 0.1408814850470565 1.0 0.3092920684463476 31 P16435,Q9NZJ7,Q9UHX1,P07602,Q96HY6,Q13510 6 +Death in infancy 0.369839812805812 1.472443344643802 0.1409011956297015 1.0 0.3092920684463476 60 Q9Y5Y5,Q13277,O75718,Q15067,P04062,Q9NZJ7,O43464,P20674,P07602,P40855,Q9BUB7,P16278,O75381 13 +Abnormal palmar dermatoglyphics 0.3638790146894232 1.4693768832944354 0.1417305938005257 1.0 0.3106734616107525 63 Q9Y5Y5,O95202,Q8NCH0,Q9UHX1,Q71SY5,P40855,O75381,P98175,Q9Y487 9 +Profound global developmental delay 0.5251230513745968 1.4683242942778885 0.1420161548423477 1.0 0.3110066992269186 15 Q9Y5Y5,Q9GZY8,O75381,P40855 4 +Urinary urgency 0.6412191809900436 1.4649170430827347 0.1429435523229083 1.0 0.3124500547724576 7 P04062 1 +Abnormal liver morphology 0.3106643880377158 1.46431737696397 0.143107251410413 1.0 0.3125145696529319 238 P10619,P00813,O60762,Q14108,Q96CU9,P20674,P15586,P00846,Q9BT22,Q8IY17,Q96HY6,O43676,P40855,O43772,Q5XKP0,Q13510,O75306,P16278,Q96AA3,O15118,Q7Z4L5,P22626,Q8N183,P53634,Q9NX14,P09601,P22830,O75880,Q14739,P36551,P07602,P51798,P61916,Q96EY8,Q86Y39,P14174,P54802,Q9Y5Y5,P50416,Q8N511,Q15067,Q9NPL8,P04062,P31751,Q16625,Q9H0U3,Q9NSD9,Q9BUB7,P28288,Q8N5M1,P33991,P08236,Q96A33,P09622,Q9Y619,Q9NZJ7,O75489,P03886,P00374,P04066,O75845,P10253,Q9HC07,Q10713,P22413,Q01844,Q9BW92,Q9NVI7,O75381 69 +Clonic seizure 0.6228956021339725 1.463156287718469 0.1434246187181569 1.0 0.3130608594138589 8 P07602,Q9H936,Q9NZJ7 3 +Photophobia 0.4127508911712437 1.4602643971649785 0.144217422869098 1.0 0.3146439136881773 40 P51648,Q15555,P04439,Q9NZJ7,Q8WWV3,P01889,Q6P4Q7,Q86YV9,P07602,Q8IY17,Q96S66,O60220,Q9NZ08,Q9Y287 14 +Prominent superficial blood vessels 0.554826235982832 1.459382002706457 0.1444599966667819 1.0 0.3150255919821488 12 Q9Y487 1 +Abnormal endocardium morphology 0.5010005383155761 1.4589554816805532 0.1445773610652141 1.0 0.3151339952464985 17 P04062,P01889,P22413,Q9NZ08,P06280 5 +Epiretinal membrane 0.5786510568877166 1.4582501860965422 0.1447715952443917 1.0 0.3154097711171079 4 P25054,P04439 2 +Lambdoidal craniosynostosis 0.5782655233529371 1.456205111342616 0.1453359269760801 1.0 0.3162447392908198 4 P61978 1 +Tongue fasciculations 0.5542762716522054 1.4561161332964871 0.1453605183673993 1.0 0.3162447392908198 12 Q13510,O95831 2 +Juvenile onset 0.4122459303687905 1.4553868363996163 0.1455621985915667 1.0 0.3162447392908198 40 P07196,O15118,Q9NR77,Q14566,P16278,P51798,Q9H0U3,P50402,Q13510,O14773,P54802,P06280 12 +Progressive 0.3247676428955103 1.4537941798936909 0.1460033775751552 1.0 0.3169076107852158 107 O60762,P15586,Q8IY17,Q5XKP0,Q13510,Q99720,P31749,Q8N183,P27544,Q9GZY8,Q86U42,O75569,P54802,Q9Y5Y5,O60313,P04062,O75298,Q13126,O95831,Q96D71,P28288,P12235,O95470,Q9NR28,Q9H0B6,Q13501,Q03252,Q9Y4W6,Q8N1F7,P20700,P07942 31 +Metaphyseal dysplasia 0.5534544561495744 1.45123467406973 0.1467145247115733 1.0 0.3183028673062452 12 Q9HC07,O95831 2 +Abnormal tongue morphology 0.3451046958320803 1.45048001545511 0.1469247081439748 1.0 0.3186104704537406 76 P07196,Q05086,P61978,P01889,P48651,Q9H9S5,P16278,P31749,Q6NUK1,P07686,Q9Y5Y5,O43924,Q7LGA3,Q9Y4P3,Q71SY5,O75844,Q96A33,P98175,O15460,Q03252,P04066,O75648,P10253,Q10713,P20700,O60826 26 +Respiratory arrest 0.6379110117161352 1.4486082360592232 0.1474470198396678 1.0 0.3194955385623414 7 O43772,P23786,P13473 3 +Breech presentation 0.6015236857878569 1.4485258862035817 0.1474700317537642 1.0 0.3194955385623414 9 O75718,Q969X5,Q9Y619 3 +Abdominal pain 0.3485150583733361 1.4454654271345169 0.1483271972964595 1.0 0.3207768050894127 86 Q70HW3,Q14108,Q14C86,P04062,P36551,P01889,P42892,Q9Y4P3,Q8N1F7,Q01844,Q13423,Q8NFH4,P35637,Q9NZ08,P14174,P06280 16 +Generalized onset motor seizure 0.3832680268035981 1.4452897002639091 0.1483765297137271 1.0 0.3207768050894127 52 Q05086,Q9Y619,P04062,Q9NZJ7,Q96N66,P03886,Q9H936,Q01105,P16278,P07602,P00846,Q9H3H1,Q05639,Q13510,Q8TAB3 15 +Rimmed vacuoles 0.5104566254268417 1.4451856117464756 0.1484057567556214 1.0 0.3207768050894127 16 P22626,P50402,P31483,P09651,Q9BTV4,P43243,Q13501,Q86U42,O14979,Q13642 10 +Abnormality of the supraorbital ridges 0.4491427438109124 1.442508931251014 0.1491588538660073 1.0 0.3222254315903262 25 Q9Y5Y5,P16435,P40855,P38159,O75381,P98175 6 +Abnormal metabolic brain imaging by mrs 0.509950576672584 1.4418217566399338 0.149352663547341 1.0 0.3222254315903262 16 P07602,P03886,P00403,Q9NZJ7 4 +Decreased activity of mitochondrial complex iv 0.4983336441577459 1.4406829215795245 0.1496742819298309 1.0 0.3227698172357187 17 Q70HW3,Q9Y2R0 2 +Hyperactive deep tendon reflexes 0.5999262459664463 1.4400192557141238 0.1498619513188823 1.0 0.323024974198683 9 Q9NR77 1 +Abnormal macrophage morphology 0.6531566912862914 1.43954521036754 0.1499961102570925 1.0 0.3230703734610461 6 O15118,P61916,Q13510 3 +Gingival bleeding 0.5609688837355394 1.4394547212013349 0.1500217298832638 1.0 0.3230703734610461 11 Q14108 1 +Short columella 0.4838709677419435 1.4375664851475098 0.1505570959746727 1.0 0.3235700057162549 2 P49711 1 +Muscle hypertrophy of the lower extremities 0.5990146934221104 1.4351631872128476 0.1512406010929128 1.0 0.3246445713782432 9 Q9NR77 1 +Abnormal macular morphology 0.4340991651969202 1.434222606192988 0.1515087479012933 1.0 0.325026432331462 29 Q13510,P50897,P04062 3 +Stroke 0.4199956118790994 1.4332514919711048 0.1517859791027918 1.0 0.3250662485796801 32 O95721,P06280,P03886,P05067,P22413,O75844,P00403 7 +Constitutional symptom 0.3083571577681256 1.431540447306156 0.1522753834564485 1.0 0.3259644927114601 242 P07196,Q14108,P01889,P42892,O15269,Q9H9S5,P00846,Q68CQ7,Q96HY6,O75874,Q13510,P35637,Q99720,P31749,Q70HW3,P22626,Q9NR77,P36551,Q14739,P07602,P48735,Q15800,Q4J6C6,P50402,Q9NZ08,P14174,Q14C86,O60313,P0DP25,Q92804,P04062,O75298,Q9Y4P3,Q3ZCQ8,O75844,Q8NFH4,Q15165,O15460,Q9NZJ7,Q13501,P22413,Q8N1F7,Q01844,Q13423,Q9H6K4,P06280 46 +Avascular necrosis 0.4557271644603006 1.430361592762605 0.1526132654886287 1.0 0.3263877826657634 22 Q14108,O75844,P04062 3 +Thin ribs 0.518913644792032 1.4282625215831348 0.1532163109529771 1.0 0.3273768699169576 15 O75844,O95831,Q9Y619 3 +Chorioretinal dysplasia 0.6335620924035238 1.4271452786550929 0.1535380235998671 1.0 0.327763571919423 7 P53701,Q9H9S5,O43505 3 +Hyperintensity of cerebral white matter on mri 0.4574713596899894 1.425533739927873 0.1540029742606716 1.0 0.3284550614039417 21 Q96AA3,Q9NZJ7,P10253,Q9P0J1,P07602,O43681,P21912,O75503,P20700,P17900 10 +Abnormal ossification involving the femoral head and neck 0.5720366551947442 1.423131778707247 0.1546979575825022 1.0 0.3287331598628173 4 Q7RTS9 1 +Hyperlipidemia 0.4278797223611607 1.4202211265326998 0.1555433149768885 1.0 0.330337877163067 30 O95470,P22830,O75844,P50402,P06280 5 +Abnormal liver physiology 0.6490342989875711 1.4199004717973935 0.155636658573147 1.0 0.330337877163067 6 Q13510 1 +Abnormality of the parathyroid gland 0.4515498486622432 1.417411556996078 0.1563626357204748 1.0 0.330911929661959 23 Q96DF8,P03886,P48735,O75874,P00403 5 +Equinovarus deformity 0.6482001591941087 1.415922950387917 0.1567980646044668 1.0 0.3315244346448333 6 Q9NR77 1 +Abnormal pharynx morphology 0.4091112361781832 1.415692428346585 0.1568655762037811 1.0 0.3315244346448333 38 P00813,Q7RTS9,O15460,P01889,P16278,P15586,Q86YV9,P08236,Q13510,P54802 10 +Steppage gait 0.4509903298688716 1.4129990971959212 0.1576559895516955 1.0 0.3330438092207701 23 P07196,P31483,Q9NR77,Q13501,O15269,Q96BR5 6 +Urinary bladder sphincter dysfunction 0.6130453949269439 1.4126961284375157 0.1577450904267321 1.0 0.3330809751621569 8 Q9NR77,O75298 2 +Dilated cardiomyopathy 0.4001323325320464 1.4107781725764617 0.1583100324717339 1.0 0.3337918553018111 44 P12235,Q9NX14,P09493,O95677,Q9BTV4,P03886,P42167,Q9H9S5,P00846,P06753,P53701,P23786,O75306,P16278,P13473,P00403 16 +Extrapyramidal muscular rigidity 0.6076676117550419 1.4090310114505002 0.1588259984499795 1.0 0.3343025308540465 5 Q9H6K4 1 +Spastic paraplegia 0.3904961364497893 1.4058265226515598 0.1597756442332876 1.0 0.3358148449934398 48 O60313,Q9Y619,O75298,P04062,Q15041,Q9H0B6,Q96CU9,P00846,O95831,O75306 10 +Calcinosis 0.6458289183509388 1.4046113831264877 0.1601368698496432 1.0 0.3361892314152294 6 O75844 1 +Joint stiffness 0.3623585922916159 1.4045490677878785 0.1601554110155418 1.0 0.3361892314152294 61 P51648,P31749,P16435,P01889,P15586,Q9Y4P3,O75874,P48735,O75844,P50402,P08236,P16278,P54802 13 +Generalized clonic seizure 0.6286675359166223 1.4029591936441357 0.1606290076877812 1.0 0.337031494508867 7 P07602,Q9H936,Q9NZJ7 3 +Acute coronary syndrome 0.456495344573113 1.4014029382948978 0.1610936141230465 1.0 0.3378541443427064 20 P01889,P22413,O75844,Q9NZ08,P06280 5 +Multifocal cerebral white matter abnormalities 0.6060072600268951 1.4006769862737696 0.1613106876449086 1.0 0.3381571480873017 5 Q9Y619 1 +Basal ganglia gliosis 0.5924802607334585 1.4003136177201032 0.1614194247104929 1.0 0.338232874629544 9 P00846 1 +Lumbar scoliosis 0.5219064535228011 1.398132688365822 0.1620732253650314 1.0 0.3391451409480308 3 P36776,P27635 2 +Recurrent respiratory infections 0.3194739435746628 1.3970301357339243 0.1624045090752592 1.0 0.339685767073443 123 P00813,Q13277,P01889,P15586,Q13510,P16278,P78318,P53634,P09601,P07602,P51798,Q8N5M9,P14174,P54802,Q9Y487,O95298,Q9NPL8,P04062,Q86YV9,Q9Y4P3,Q71SY5,P08236,P33991,O15460,Q9NZJ7,O95202,Q9H936,P04066,P10253,Q7RTS9 30 +Autophagic vacuoles 0.4770642201834942 1.395400861286834 0.1628949917532827 1.0 0.340198749319404 2 P35609 1 +Broad palm 0.6096602760502954 1.395322410312529 0.162918637080123 1.0 0.340198749319404 8 O95831,Q7RTS9 2 +Memory impairment 0.4042853241426143 1.3948075341176107 0.163073886346132 1.0 0.340198749319404 41 P31749,P31483,Q9NZJ7,Q13501,P03886,P01889,P05067,P07602,Q9NZ08,P00403 10 +Abnormal urinary color 0.6437628322174237 1.3947501794150383 0.1630911872622662 1.0 0.340198749319404 6 P23786,P36551 2 +Aplasia hypoplasia of toe 0.4068981840437648 1.394518739684635 0.1631610145941495 1.0 0.340198749319404 38 P00813,P13073,O95202,Q8N3R9,Q9UHX1,Q7LGA3,Q13510 7 +Paroxysmal involuntary eye movements 0.4530909709715702 1.3918609737314382 0.1639645016839215 1.0 0.3412630245056776 21 Q8N183,Q9NPL8,O75489,P03886,Q96CU9,O43676,O75306,Q86Y39 8 +Slowly progressive 0.3684856708296843 1.379273754853648 0.167810365292113 1.0 0.3479490538866703 56 P07196,O14979,O00584,P31483,Q9NR77,Q8IV08,O95831,Q96BR5,P50402,O14773,Q99720,Q8N2K0 12 +Epistaxis 0.521716477040336 1.3791477975309023 0.1678491893695466 1.0 0.3479490538866703 14 O15460,P04062,P38435,P01889,Q86YV9 5 +Macrovesicular hepatic steatosis 0.640334201456918 1.3783751637244988 0.1680874874348861 1.0 0.3482880411350976 6 Q5XKP0,O75648 2 +Abnormal left ventricle morphology 0.4138592903812825 1.3777508980259467 0.1682802108117207 1.0 0.3485323352427724 32 P12235,P06280,O75880,Q6NUK1,P03886,P00533,P10253,Q9H9S5,P21912,O00170,P78536,Q15233,O75208,P00403 14 +Abnormal esophagus physiology 0.3069046712753198 1.3751560432185792 0.1690830726667487 1.0 0.349728664512307 234 Q05086,Q14108,Q96PU5,P55795,P01889,Q01105,O15269,P15586,P00846,O75874,O75306,Q13510,P35637,Q99720,O15118,Q9NR77,P16435,Q14739,Q9GZY8,P05067,P07602,P61916,P48735,Q8IZA0,Q9Y5Y5,O60313,P51571,Q15067,P04062,Q9Y4P3,Q96D71,Q9NSD9,O60220,Q96A33,Q9Y619,Q9NZJ7,O75489,O95202,P03886,Q13501,Q9H936,Q9UHX1,Q05639,P06280 44 +Dyskinesia 0.3458019371769233 1.3748753260677506 0.1691700999931134 1.0 0.3497533625245992 68 Q08J23,P04062,Q9UBX3,Q96N66,Q9BPX6,P03886,Q01105,Q9H936,P00846,Q2M389,Q71SY5,Q05639,O75306,O43464 14 +Exostoses 0.6007468276823031 1.3741868874784129 0.1693836704746543 1.0 0.3498843179915475 5 O75874,P48735 2 +Progressive visual field defects 0.4732169280852405 1.3715313668237354 0.1702093723921769 1.0 0.350860773973726 2 P35222 1 +Abnormality of the gallbladder 0.3961734060423018 1.3707901301247107 0.1704403885775449 1.0 0.3509775994669338 44 P04062,Q9NZJ7,P22830,O95202,P04066,O75845,P07602,Q9Y4P3,P40855,Q71SY5,Q96A33 11 +Cardiac conduction abnormality 0.4061960202278438 1.3691922933218446 0.1709391743928601 1.0 0.3516937607429074 35 P50402,P06280,P03886,P00846,O75306,P00403 6 +Waddling gait 0.4264498390273157 1.3683884265434985 0.1711905249742058 1.0 0.3520553930816118 29 P07196,P22626,O75340,Q8TD16,P09651,Q9BTV4,Q5T8D3,Q8WVQ1,Q9H9S5,P06753,Q4J6C6,P50402,Q13510,Q7RTS9 14 +Abnormal basal ganglia mri signal intensity 0.4218164363276808 1.3671447284068523 0.1715799458052229 1.0 0.3527005240779914 30 Q9GZY8,Q96CU9,Q9BPX6,Q8NI60,P03886,P00846,O75306,P16278 8 +Abnormality of amino acid metabolism 0.4717372003551429 1.362344351107153 0.173089237048075 1.0 0.3550196680624982 2 P18074 1 +Flat nasal alae 0.4717372003551429 1.362344351107153 0.173089237048075 1.0 0.3550196680624982 2 P18074 1 +Inverted nipples 0.5664413589311645 1.360026817541229 0.1738214376492481 1.0 0.356207767958732 10 Q96AA3,O60762,P61978,Q15067 4 +Fractures of the long bones 0.5600351511106142 1.3592519533984455 0.1740667633586272 1.0 0.3565474294875868 4 P51798,Q13501 2 +Abnormality of salivation 0.394840303980751 1.3573006171973232 0.1746857113173734 1.0 0.3571931709026889 44 Q05086,Q9NR77,Q92804,Q14739,Q13501,P55795,P01889,P15586,Q68CQ7,P35637,Q8TAB3,Q15165 12 +Orthostatic hypotension 0.517983987488758 1.3556310192800276 0.1752165972039243 1.0 0.3576507054232601 14 Q9NZJ7,P04062,P07686,P07602,O43681 5 +External ophthalmoplegia 0.4738431066563868 1.3508406560840809 0.1767464814223256 1.0 0.3602971433864676 18 O60313,P12235,Q8N183,P03886,Q9GZY8,P21912,P00403 7 +Papule 0.4737758624782848 1.3503620924126432 0.1768998640886327 1.0 0.3602971433864676 18 P31749,P38435,P01889,O75844,Q9NZ08 5 +Calvarial hyperostosis 0.5955625907998517 1.3480494528984306 0.1776424774391998 1.0 0.3614935167810366 5 P31749 1 +Perseveration 0.5822589670473247 1.3456743657989765 0.1784075569212333 1.0 0.3628918777900021 9 Q13501,P61916,P35637 3 +Primary adrenal insufficiency 0.4844491322434944 1.3452160065922198 0.1785554885872244 1.0 0.3630342496024843 17 Q9Y5Y5,P31749,Q13423,P40855,O75381 5 +Abnormal tongue physiology 0.4727798316626274 1.3432720716455808 0.1791838919620441 1.0 0.3640122573109616 18 Q9BQT8,Q13510,O95831 3 +Polydactyly 0.3681707306217501 1.343244522615232 0.1791928093632535 1.0 0.3640122573109616 54 P61978,Q15125,P21964,Q8IY17,Q7Z4L5,Q14739,O43924,O00192,Q15067,Q8WXW3,P54198,Q9BRT2,P98175,O95202,O75845,Q9UHX1,Q10713,Q9Y263,O60826 19 +Thyroiditis 0.5816597886459455 1.3424669922664356 0.1794446258391788 1.0 0.3643648941407563 9 P00813 1 +Vertical nystagmus 0.4684817993489281 1.3421212394334625 0.1795566882626935 1.0 0.3644335746961336 2 P50542 1 +Abnormality of fundus pigmentation 0.6318485261849829 1.3377953413493702 0.1809631609445132 1.0 0.3660327610284763 6 Q9Y619 1 +Multiple prenatal fractures 0.6300429905648437 1.3291520848241185 0.1837977994626756 1.0 0.3711528821136817 6 Q14739,O75718,Q32P28 3 +Astrocytosis 0.5967472948801883 1.328912529267882 0.1838768297031578 1.0 0.3711528821136817 8 P00846 1 +Brittle hair 0.513677940607544 1.3284652255158418 0.1840244641826651 1.0 0.3711528821136817 14 O75844,Q9Y487 2 +Impaired tactile sensation 0.612994452266026 1.3253194836114697 0.1850652094530551 1.0 0.3722080076132689 7 Q9NR77 1 +Increased serum pyruvate 0.4025882300895646 1.3245023645829506 0.1853362582762285 1.0 0.3725733665637469 34 Q70HW3,Q9BWD1,P03886,P22695,O95831,O43676,Q86Y39 7 +External ear malformation 0.470114981344902 1.3242897280938069 0.1854068406386357 1.0 0.3725733665637469 18 Q9Y5Y5,O75381,Q8NCH0,P40855 4 +Biliary cirrhosis 0.6289269572062818 1.3238080881797656 0.1855667892632673 1.0 0.3727339820561876 6 P09601,P14174 2 +Prominent antitragus 0.4652263983427109 1.3218833011799191 0.186207013822313 1.0 0.3735367228184041 2 Q92643 1 +Mania 0.512147842972008 1.3188036119912825 0.1872347764141193 1.0 0.3751138015212765 14 P12235,P16615,O00192,P03886,P54198,P00403 6 +Decreased absent ankle reflexes 0.511945596514928 1.317526226900094 0.1876622958237175 1.0 0.3754605149023993 14 P07196,Q15041,Q9H6K4,O60313 4 +Abnormality of tibia morphology 0.5017947605927607 1.317323362324671 0.1877302574511996 1.0 0.3754605149023993 15 Q32P28,P16435,P22413,O95831,Q7RTS9 5 +First degree atrioventricular block 0.5519692034349908 1.3162216029235394 0.1880996749492811 1.0 0.37587657053357 4 P02545,Q99996,Q14BN4 3 +Abnormal pleura morphology 0.4386321920330263 1.315225689092527 0.1884340639740593 1.0 0.3762219759927855 23 Q14739,P01889,Q8NCH0,P08236,Q9NZ08,P14174 6 +Abnormal glial cell morphology 0.3581499601830825 1.3127990936576108 0.189250655532706 1.0 0.3776904684967201 59 P04062,P00846,Q9H9P8,O95831,P48735,Q10713,P35637 7 +Ulnar deviation of the wrist 0.5067558652373807 1.311182332489869 0.1897961698538377 1.0 0.3784548626623186 3 P16278 1 +Decreased number of large peripheral myelinated nerve fibers 0.5877811357089832 1.3087663129013534 0.1906135212642563 1.0 0.3793126416888916 5 P07196 1 +Abnormal gallbladder morphology 0.3981659807938604 1.3052069427323962 0.1918223907444072 1.0 0.3803783295391438 36 P04062,Q9NZJ7,P22830,O75845,P07602,Q9Y4P3,P40855,Q71SY5,Q96A33 9 +Abdominal distention 0.434527012440849 1.3023137870255657 0.1928091405054293 1.0 0.3818473539431504 24 Q9NZJ7,P04062,P07602,O43681,Q96HY6,Q01844,Q7RTS9 7 +Abnormal systemic blood pressure 0.3140413261603531 1.301005623631622 0.1932565298112212 1.0 0.3825707249726597 96 P01889,P42892,P35610,P21964,O43772,P00403,P16435,P36551,P07686,P07602,P21912,O00192,Q02978,P04062,Q9Y4P3,P54198,O75844,Q9NSD9,Q9BUB7,P28288,Q13263,Q9NZJ7,P03886,O43681,Q10713,P22413,Q13423,P20700,P06280 29 +Deep palmar crease 0.5281388271131467 1.3002084067483446 0.1935295501048404 1.0 0.3826831703419814 12 P98175,Q9Y487 2 +Decreased activity of mitochondrial complex i 0.3977549547141157 1.2999741716953164 0.1936098216402548 1.0 0.3826831703419814 39 O95298,Q70HW3,Q8N183,Q9NPL8,O75489,Q9UBX3,Q96CU9,P03886,O43676,O75306,Q86Y39 11 +Abnormal endocrine physiology 0.5860224654914539 1.2998804216292508 0.1936419563108737 1.0 0.3826831703419814 5 Q13423 1 +Vertebral compression fracture 0.4886179440307757 1.2994109679933892 0.1938029296457331 1.0 0.3828388661110368 16 Q96HY6,O75718,Q14108,P04062 4 +Abnormal echocardiogram 0.5486458874678841 1.2984732695782188 0.1941247558742411 1.0 0.3829873413224122 4 P12235 1 +Recurrent fever 0.5273863512205228 1.2957024679996545 0.1950780107673857 1.0 0.3842797090759025 12 P61978,Q13510,Q9NR77 3 +Occipital encephalocele 0.6068237464024913 1.2946827940738328 0.195429677827329 1.0 0.3845522683414115 7 Q9H9S5,Q10713 2 +Clonus 0.4085740295881421 1.2902061019043825 0.1969791081045446 1.0 0.3871429052957675 31 Q9Y619,O75298,Q9BQT8,Q9NZJ7,O60220,Q9H9S5,P07602,Q3ZCQ8,P35637 9 +Vertebral fusion 0.5351455455601807 1.2892107247499804 0.1973248375411491 1.0 0.3874954018830829 11 Q9UHX1,O95202,Q9H9S5 3 +Severe short stature 0.4297697763058611 1.2850052347459535 0.1987904547709698 1.0 0.389388535880226 25 P10619,Q9Y619,Q8WVQ1,P48651,P53701,Q96HY6,Q8IY17,P16278,Q15392,Q7RTS9 10 +Cutaneous syndactyly 0.5161259193260783 1.28336738740586 0.1993633939350778 1.0 0.3901826424157952 13 P98175 1 +Fatigue 0.3356609688476278 1.2819789561225785 0.1998500284127267 1.0 0.3909707821698786 80 O60313,Q70HW3,Q92804,P04062,Q9NZJ7,Q14739,O15460,P01889,P07602,Q68CQ7,Q13423,Q4J6C6,P35637,Q9NZ08,Q15165,P06280 16 +Bilateral talipes equinovarus 0.6033147598197747 1.2772468295488204 0.2015151187166566 1.0 0.3937321405126621 7 Q15125 1 +Abnormality of the palm 0.3122991448421339 1.2759120327001672 0.2019866170456643 1.0 0.3941000659967671 123 Q15907,O60762,P09493,P07858,P61978,Q9Y2B2,P48651,Q8IY17,P40855,P16615,P31749,O95721,P53634,P16435,Q14739,Q9Y487,Q9Y5Y5,Q8NCH0,P42167,O95831,Q71SY5,P98175,Q15555,Q9Y619,O95202,Q9UHX1,P22413,O75381,Q7RTS9 29 +Microdontia 0.4114253791909577 1.2757558063180228 0.2020418543581537 1.0 0.3941000659967671 30 Q15555,Q9Y619,Q9Y2B2,Q9Y4P3,Q7LGA3,Q96A33,Q9Y487 7 +Multicystic kidney dysplasia 0.4397030954537442 1.2733963512717463 0.202877431488917 1.0 0.3953987765168935 20 Q9Y5Y5,Q10713,P40855 3 +Paraplegia 0.3727413295852744 1.2696883730512292 0.2041956560284079 1.0 0.3976351863630118 50 O60313,Q9Y619,O75298,P04062,Q15041,Q9H0B6,Q96CU9,P00846,O95831,O75306 10 +Onychogryposis 0.5431627893448129 1.2691701329312113 0.2043803909658381 1.0 0.3976624315450602 4 P78536,P53634 2 +Hypointensity of cerebral white matter on mri 0.6172071175699154 1.2676294697913808 0.2049303027607758 1.0 0.3982333543010821 6 P07602 1 +Late onset 0.5498182286880613 1.2671894090796876 0.2050875718067277 1.0 0.3983727729256621 10 Q9Y6M1,P31483,O76024,P31751,P22413,P18031 6 +Ovoid vertebral bodies 0.6011487845047074 1.2664795799761506 0.205341435652647 1.0 0.3986996278741267 7 P15586,P54802 2 +Aplasia of the phalanges of the hand 0.456052086416108 1.264783192009303 0.205949058189204 1.0 0.3995463194691022 2 P02545 1 +Aplasia hypoplasia of the proximal phalanges of the hand 0.4560520864161079 1.2647831920093016 0.2059490581892045 1.0 0.3995463194691022 2 P42345 1 +Ectrodactyly 0.4503130598041308 1.2643808476617633 0.2060933637666582 1.0 0.3996598203268501 19 P07196,O95202,Q9Y297,Q9NR77 4 +Talipes equinovarus 0.3385663167353861 1.2615089032626925 0.2071255542882482 1.0 0.4008271009034733 84 Q9NWM8,Q9NR77,Q9Y619,P16435,P61978,Q15125,O95202,Q8NI60,Q8WVQ1,Q969X5,Q8NCH0,O75845,Q96A33,P08236,Q15392,Q9Y487,Q7RTS9,P98175 18 +Generalized muscle weakness 0.3942334651504346 1.2565555874682433 0.2089146053710058 1.0 0.4028750705258335 35 Q92804,Q13501,P10253,Q9H9S5,Q68CQ7,O95831,P35637,Q15165 8 +Skin ulcer 0.4091818654387507 1.255959164971102 0.2091307757010643 1.0 0.4028750705258335 30 P04062,Q14739,P01889,O15269,P48735,O75874,Q8IZA0 7 +Hemiparesis 0.471445037035008 1.2553606521303928 0.2093478665083101 1.0 0.4031179670093876 17 P31749,P03886,P01889,Q9NZ08,P00403 5 +Abnormal skin morphology of the palm 0.3117043264547567 1.2541647695276676 0.209782122291541 1.0 0.4036204566848402 100 Q15907,P09493,P07858,P61978,Q9Y2B2,Q8IY17,P40855,P16615,P31749,O95721,P53634,Q14739,Q9Y487,Q9Y5Y5,Q8NCH0,P42167,Q71SY5,P98175,O95202,Q9UHX1,P22413,O75381 22 +Abnormality of exocrine pancreas physiology 0.4913176039724019 1.2491279760501544 0.2116182697239963 1.0 0.4056452264915123 15 P09601,P14174 2 +Venous thrombosis 0.5010585912566883 1.2486620793500074 0.2117886960662875 1.0 0.4058049141409986 14 P31749,O75874,P01889,P48735 4 +Abnormal rib cage morphology 0.3360090292061987 1.2479981784402716 0.2120317242717022 1.0 0.4058309911444411 85 P00813,P31749,O75718,Q32P28,Q9Y619,P16435,Q14739,O95202,P04066,P16278,Q9UHX1,P15586,Q96HY6,O95831,O75844,Q7RTS9,P54802 17 +Limb girdle muscular dystrophy 0.5809810140701029 1.2475901458546734 0.2121811890178873 1.0 0.4058309911444411 8 P50402,P09651,Q9BTV4,O14979,Q13642 5 +Limitation of movement at ankles 0.5391060569336785 1.2474761032056625 0.2122229771213062 1.0 0.4058309911444411 4 O75844 1 +4 5 toe syndactyly 0.4530926309559125 1.2463476285404058 0.2126367992423758 1.0 0.4064268407349146 2 P35453 1 +Abnormal cranial nerve physiology 0.3308461204378778 1.2455976419753838 0.2129121484256213 1.0 0.4067521108719884 77 Q9Y5Y5,P07196,P31749,Q9NR77,Q9NZJ7,Q13501,P01889,P48651,Q9UHX1,P07602,Q9H9S5,P48735,O75874,P40855,Q13510,Q9NZ08,O75381 17 +Cerebral dysmyelination 0.5964893979883001 1.2433066868519609 0.2137548410468559 1.0 0.4078943259304609 7 P07602 1 +Pustule 0.5744858109996837 1.2415339440305928 0.2144085667446678 1.0 0.4086897713158812 5 P07858,P53634 2 +Beaking of vertebral bodies 0.5625779086125635 1.2401150277543966 0.214932851343107 1.0 0.409223197442713 9 P16278,Q7RTS9,P04066 3 +Abnormality of the brainstem white matter 0.4941991673544121 1.2389330750323186 0.215370283638534 1.0 0.4096344553647577 3 Q10713 1 +Mutism 0.4795314364245976 1.238447530708546 0.2155501658755638 1.0 0.4096735546090262 16 Q13501,P22626,Q13510,P35637 4 +Hypothermia 0.526416374595446 1.2382038253741554 0.2156404934931077 1.0 0.4096735546090262 11 P03886,P00846 2 +Cranial asymmetry 0.6108307046095599 1.237026481782017 0.2160772513902649 1.0 0.4103089429171846 6 O95202 1 +Recurrent paroxysmal headache 0.5440795395516191 1.2350679204019754 0.2168052272464022 1.0 0.4115235324016877 10 P00403 1 +Chronic fatigue 0.5947547946618659 1.2346765146422485 0.2169509198175321 1.0 0.4116323358493134 7 P07602,Q13423 2 +Aplasia hypoplasia of the cerebral white matter 0.5614478534722172 1.2340431578210502 0.2171868227731286 1.0 0.411678911797255 9 P00403 1 +Hyperextensible skin 0.4986208625602009 1.233218153570964 0.2174943842225378 1.0 0.4119922089095491 14 Q9UHX1,Q9NWM8,Q8NCH0,P04062 4 +Cystic liver disease 0.5721358151826048 1.2296391680947718 0.2188322558631426 1.0 0.4141896171517749 5 Q7Z4L5,Q9UGP8 2 +Metaphyseal striations 0.5925896321886686 1.2239019518754786 0.2209892172155494 1.0 0.4174240769627044 7 P00813,Q9UG56 2 +Abnormality of the basal ganglia 0.3326050086903135 1.2228612689614502 0.2213820994119206 1.0 0.4176380698524967 86 O60313,Q08J23,P04062,P03886,Q8NI60,Q96CU9,Q9BPX6,Q96N66,Q9GZY8,P00846,Q2M389,O95831,Q71SY5,O75306,P16278,O60220,P00403 17 +Secondary microcephaly 0.3299246269892956 1.2226585756550203 0.2214586790917565 1.0 0.4176380698524967 78 P50897,Q05086,O95721,O43464,Q5T8D3,Q96CU9,P00374,P55795,Q9GZY8,Q9H936,Q9UHX1,Q9HC07,Q05639,Q5XKP0,Q86Y39,O75208,Q9Y487 17 +Mortality aging 0.3102313290450873 1.2206935715711715 0.2222020626307606 1.0 0.4186197657021481 107 Q13277,P20674,Q9H9S5,P40855,P16278,O75718,O95721,P16435,Q14739,P05067,P07602,Q9Y5Y5,Q15067,P04062,Q9Y4P3,O75844,Q9BUB7,O43464,Q9NZJ7,Q9H936,Q9NVI7,Q96IX5,O75381 23 +Decreased muscle mass 0.4664069756902478 1.2204561516285968 0.2222920021678884 1.0 0.4186197657021481 17 O95202,Q9Y487,P04066,Q8NCH0 4 +Lymphoproliferative disorder 0.5703053370180917 1.2203722721309425 0.222323783670459 1.0 0.4186197657021481 5 P33991 1 +Diffuse white matter abnormalities 0.5410824826481362 1.2182811944020957 0.2231171338929276 1.0 0.4186207418582538 10 O75306,Q9H9S5,P16278,Q3ZCQ8 4 +Furrowed tongue 0.590567935399575 1.2138393067978137 0.2248090931761948 1.0 0.4202089711134492 7 P61978,Q71SY5 2 +Abnormal talus morphology 0.4298186761383062 1.211878068574301 0.2255590584652091 1.0 0.4211038454232242 21 Q9UHX1,O75844,P16435,P98175 4 +Postaxial hand polydactyly 0.494881469147888 1.209513204673792 0.226465741157277 1.0 0.4224579184263501 14 O43924,Q7Z4L5,Q14739,O75845,Q9Y263,Q10713 6 +Vocal cord paresis 0.4890467732386099 1.2092578063665504 0.226563815551346 1.0 0.4224716784780504 3 P36776,P43243 2 +Esophageal varix 0.5318046264822682 1.2084086777463117 0.2268901035519035 1.0 0.4227416409379066 4 P04062 1 +Retinal dysplasia 0.5392097511903764 1.2077885792397425 0.2271285955726112 1.0 0.4230167925538676 10 Q9NX14,P53701,Q9H9S5,Q10713,O43505 5 +Overlapping toe 0.4249610755124353 1.2064521186876256 0.2276432105129107 1.0 0.4238057851994956 23 Q15907,P61978,Q15125,Q9UHX1,Q71SY5,Q96A33 6 +Obsessive compulsive trait 0.6041846212002497 1.2051088900243845 0.2281612683103953 1.0 0.4241843903987812 6 O75503 1 +Confetti like hypopigmented macules 0.4878812490654313 1.2025436084513943 0.2291529810397183 1.0 0.4255796153339826 3 Q15233 1 +Impaired social interactions 0.3544734961582825 1.2010351070331229 0.2297375833812791 1.0 0.4261719089565903 55 O95298,Q15907,Q8N183,Q15067,Q9NPL8,O75489,O43464,Q9GZY8,Q96CU9,P03886,Q9UHX1,O43676,O75306,Q5XKP0,Q86Y39 15 +Bulbar palsy 0.5196638362128245 1.198695288729244 0.2306464506445684 1.0 0.427687566521656 11 P31483,Q13501,O43681,Q9Y263,P06753,P35637 6 +Cerebral visual impairment 0.3320074921677568 1.1951601663835032 0.2320244583836075 1.0 0.4295587945750572 68 Q96N66,Q96CU9,P03886,Q01105,Q2M389,Q71SY5,Q05639,O60220,Q96A33,P00403 10 +Absent epiphyses 0.5698936434900338 1.1902940167155485 0.2339308516384668 1.0 0.4318148720180878 8 Q7LGA3,Q7RTS9 2 +Polymicrogyria 0.3318009886383464 1.1892030793854866 0.2343597630534359 1.0 0.4323357529912494 85 Q9Y5Y5,O95721,Q08J23,Q96N66,Q01105,Q9H9S5,Q10713,O43505,Q2M389,Q8WXW3,P40855,Q05639,Q71SY5,Q16625,Q15392,O75381,Q9Y487 17 +Axonal degeneration 0.5689730193628105 1.185533967940917 0.235806392587349 1.0 0.434451213177719 8 Q6DKK2 1 +Severe expressive language delay 0.4430304823912486 1.183634184938824 0.2365579021547055 1.0 0.4352421385182738 2 Q8NB90 1 +Motor axonal neuropathy 0.4711331800311883 1.1819834298510508 0.2372122757574724 1.0 0.4360095150635661 16 Q9H0B6,P22626,O95831,O15269 4 +Abnormality of long bone morphology 0.3012604034144812 1.1817944421075 0.2372872736552469 1.0 0.4360095150635661 193 P00813,Q9NX62,Q15125,Q96HY6,O75874,P40855,P16278,P22626,O75718,Q9NR77,P16435,Q14739,Q8WVQ1,P48735,Q9Y487,Q9Y5Y5,Q9UG56,Q08J23,Q32P28,P38435,Q8N3R9,Q7LGA3,Q9Y4P3,O95831,O75844,Q71SY5,P08236,P98175,Q9Y619,O95202,Q13501,Q9UHX1,Q9HC07,P22413,O75381,Q7RTS9 36 +Adult onset 0.3288508025173606 1.1813845208555545 0.2374500043852403 1.0 0.4360619762439842 69 Q9UGP8,P43304,P31749,O15118,P36551,Q8IV08,P07602,Q86U42,P21912,P18031,Q9Y6M1,P04062,P38435,P31751,Q9H0U3,Q71SY5,O76024,Q14566,Q969G3,Q9NQZ5,P12235,P31483,P49815,Q9NZJ7,Q9BTV4,P22413,O14979,P20700,Q13642 29 +Abnormality of the musculature of the upper arm 0.5838851052826605 1.180565712842753 0.2377752911625075 1.0 0.436217922896794 7 O14979,P50402,Q13642,Q9BTV4 4 +Proximal upper limb amyotrophy 0.5838851052826605 1.180565712842753 0.2377752911625075 1.0 0.436217922896794 7 O14979,P50402,Q13642,Q9BTV4 4 +Abnormality of the parathyroid morphology 0.5982114069976396 1.176410887375554 0.2394307231795023 1.0 0.438680374917594 6 P48735 1 +Parathyroid adenoma 0.5982114069976396 1.176410887375554 0.2394307231795023 1.0 0.438680374917594 6 P48735 1 +Neoplasm of the parathyroid gland 0.5982114069976396 1.176410887375554 0.2394307231795023 1.0 0.438680374917594 6 P48735 1 +Limb muscle weakness 0.3308242146792626 1.1755298007778308 0.2397828218501219 1.0 0.4390363145353254 85 P07196,P31749,Q99720,P31483,Q15067,Q9NR77,O75298,Q9BQT8,Q14739,P36551,Q13501,Q969X5,O15269,P00846,Q96BR5,P50402,Q13510,Q7RTS9 18 +Malabsorption 0.3509145024928891 1.1749570365454307 0.2400119048256035 1.0 0.4392830855314975 56 Q9Y5Y5,Q08J23,Q14739,P09601,P01889,P22413,O75381,P40855,Q96A33,Q9NZ08,P14174,P06280 12 +Aplasia hypoplasia of the eyebrow 0.3769020094673325 1.174720481348393 0.2401065625198071 1.0 0.4392837267153422 44 P00813,Q08J23,P61978,Q15125,Q14574,O75844,Q71SY5,Q9NVI7 8 +Myoclonic spasms 0.5967299378917671 1.1692921857633396 0.2422859304166924 1.0 0.4418923921247125 6 Q10713,P00846 2 +Abnormal glycosylation 0.4243109315450824 1.1690685988546954 0.2423759941389338 1.0 0.4418923921247125 21 Q96AA3,O60762,Q8TCJ2,P51571,Q8N511,O75340,P46977,Q9BT22,Q9H0U3,Q2TAA5,Q9Y487 11 +Abnormality of the musculature of the thigh 0.5657537122156472 1.1688866528086446 0.2424493017542448 1.0 0.4418923921247125 8 P07196,O14979 2 +Hypersomnia 0.4406629180230924 1.168875278459412 0.2424538850944939 1.0 0.4418923921247125 2 O00170 1 +Aplasia hypoplasia of the scapulae 0.5244065887407217 1.1688077481692822 0.2424810979542218 1.0 0.4418923921247125 4 Q7RTS9 1 +Abnormal leukocyte physiology 0.3411587585749106 1.1672170455857651 0.2431227288952411 1.0 0.4427152741180739 62 P09601,P00813,P14174,Q14108 4 +Abnormality of the pubic bone 0.5488717353015214 1.1664207002176508 0.2434443932055288 1.0 0.4429301180491888 9 O95202,Q8IZA0 2 +Deposits immunoreactive to beta amyloid protein 0.481576279016243 1.1662188238098283 0.2435259837535364 1.0 0.4429301180491888 3 P05067 1 +Abnormal brain lactate level by mrs 0.5316991252976322 1.1656875022536322 0.2437408149673054 1.0 0.4429755375909986 10 P03886,P00403 2 +Hypopigmented skin patches 0.403042769157081 1.165274111853405 0.2439080547019092 1.0 0.4430429973813911 29 P31749,O00192,P53634,Q9NX14,Q9NZJ7,Q15125,P21964,P07602,P53701,P54198,Q8IZA0 11 +Goiter 0.5138326551962631 1.164551642921268 0.2442005276179721 1.0 0.4430429973813911 11 P12235,P31749,O75874,P48735 4 +Skeletal muscle hypertrophy 0.3698480533556745 1.1633723648053431 0.2446784568439806 1.0 0.4434329958070674 47 P31749,Q9NR77,P61978,P04066,P10253,Q9H9S5,Q7LGA3,Q9Y4P3,Q10713,P16278,Q96A33 11 +Increased serum iron 0.4810538780343529 1.1632090540384037 0.2447446939580762 1.0 0.4434329958070674 3 Q6PGP7,Q9Y276 2 +Emg abnormality 0.3248641324381724 1.163185000491903 0.2447544508844934 1.0 0.4434329958070674 77 P07196,O60313,P50402,P22626,P31483,Q9NR77,Q9NZJ7,P09493,Q13501,Q8NI60,Q969X5,O15269,P07602,Q9H9S5,O14773,Q13510 16 +Calcification of the aorta 0.5952879292366422 1.1623628637420742 0.2450881013025092 1.0 0.4436923341885301 6 P04062 1 +Heterogeneous 0.3674308328860947 1.160864931678768 0.2456968320622914 1.0 0.4446215399169205 48 P07196,P31749,Q15555,Q9NR77,P53634,Q9Y619,P03886,P01889,P05067,P00846,P61916,Q9BQE5,O75844 13 +Hypoplastic vertebral bodies 0.5581815656773312 1.1589708620450516 0.2464680623174127 1.0 0.4453251490591576 5 P16278 1 +Abnormal uvea morphology 0.3064552201567637 1.158349027022812 0.2467216315872094 1.0 0.4456104536383177 109 Q05086,P01889,Q9H9S5,P40855,Q5XKP0,P31749,Q9NR77,P78318,Q9Y297,O43505,P14174,Q9Y5Y5,Q86YV9,Q8WXW3,Q7LGA3,Q9Y4P3,Q96EK5,Q9Y619,O95202,Q9UHX1,P53701,Q10713,P22413,O75381 24 +Absent septum pellucidum 0.3829681159014415 1.1563735894351703 0.2475283795613712 1.0 0.4468942604639019 39 P51571,Q08J23,O95202,Q96N66,P53701,Q9H9S5,O43505,Q2M389,Q71SY5,Q15392 10 +Abnormal hypothalamus morphology 0.5220226424099075 1.156045685461668 0.247662470616867 1.0 0.4469631104739895 4 O43924,P35222 2 +Gliosis 0.3827671397287728 1.1544147110962035 0.2483301867710594 1.0 0.4478211420749496 39 P00846,Q9H9P8,P35637,P04062 4 +Aplasia hypoplasia of the capital femoral epiphysis 0.5785372513051547 1.153931107181326 0.2485284146578958 1.0 0.4478318589850982 7 Q7LGA3,Q7RTS9 2 +Aplasia hypoplasia involving the femoral head and neck 0.5463507693037303 1.1528577889376073 0.2489687601278962 1.0 0.448395130937261 9 Q96HY6,O95831 2 +Entropion 0.5463214453959888 1.1527000169149626 0.2490335345072336 1.0 0.448395130937261 9 O75844 1 +Lower limb amyotrophy 0.4460823314980703 1.1523858244371172 0.2491625634628844 1.0 0.448440820893196 18 P07196,Q9H0B6,Q9NR77,O75298 4 +Flared iliac wing 0.5559257986735089 1.147544578121909 0.2511566202913498 1.0 0.451404118949444 5 O95831 1 +Confusion 0.4453637720234321 1.147231033832851 0.2512861486551971 1.0 0.451404118949444 18 P05067,P01889,Q9Y619,P36551 4 +Abnormality of pain sensation 0.4068939265927969 1.140020197634704 0.2542778865731725 1.0 0.4558993054880052 27 P07196,Q9NR77,Q8NCH0,O15269,O95831 5 +Vascular calcification 0.5756424469947308 1.1395126254442074 0.2544894053686857 1.0 0.4561029819958976 7 P04062 1 +Limited knee extension 0.5186929316970276 1.1382214504657204 0.2550280238652664 1.0 0.4567360065951895 4 Q7RTS9 1 +Abnormal iliac wing morphology 0.5092117518617678 1.1374835598544373 0.2553361934042304 1.0 0.4570930011056515 11 O95831,Q7RTS9 2 +Abnormality of the metacarpal bones 0.3749839914247959 1.1371357607467665 0.2554815364895724 1.0 0.4571774863497611 43 P31749,Q9NX62,P16435,Q32P28,Q14739,O95202,Q6NUK1,Q8WVQ1,P48651,P51798,Q15233,P08236,P16278,Q7RTS9 14 +Abnormal acetabulum morphology 0.4200935378709198 1.1362495695634929 0.2558521301691749 1.0 0.4576648319232015 21 O75718,Q8WVQ1,Q969X5,P16278,Q7RTS9 5 +Abnormality of upper limb joint 0.3024851920800033 1.135256088751161 0.2562680348758015 1.0 0.4578812836407685 130 P07196,Q15125,P42892,P16278,Q13510,P31749,Q9NR77,P16435,Q8WVQ1,Q969X5,P50402,Q8IZA0,Q7LGA3,Q9Y4P3,O95831,O75844,Q71SY5,Q15392,Q9Y619,O95202,P22413,Q9H6K4,Q7RTS9 23 +Pneumothorax 0.5890965795318344 1.1326108142920297 0.2573777252337874 1.0 0.4595114772475974 6 Q9H078,Q6NUK1,P49815,Q8NCH0 4 +Symptomatic seizures 0.5586623428161426 1.132210007068457 0.2575461539401522 1.0 0.4596360095989383 8 P53985,Q13423 2 +Abnormality of the carpal bones 0.4430166046967588 1.1303890733494912 0.2583123162515677 1.0 0.4608267978168526 18 Q15125,P22413,Q7RTS9,P16435 4 +Alternating esotropia 0.4748430608907923 1.1274298917444088 0.2595607667522646 1.0 0.4625530770891589 3 P20700 1 +Airway obstruction 0.442201373674959 1.124538162926222 0.2607847900965341 1.0 0.4643484527024678 18 O00192,P16435,P09601,P21964,Q96HY6,P54198,O75844,P06280 8 +Flat occiput 0.4312078033978886 1.1228373541281704 0.2615065775935792 1.0 0.4652064197562159 19 Q9Y5Y5,Q05086,P40855,Q9BUB7,O75381 5 +Intestinal pseudo obstruction 0.5404497037376225 1.1211062811381929 0.2622426253628638 1.0 0.4658757242334933 9 P03886,P00403 2 +Stillbirth 0.505877577430478 1.117949569672528 0.2635885324163434 1.0 0.4668423513290218 11 O75844,P16435,P04062 3 +Sound sensitivity 0.5395934037585729 1.1164987794863903 0.2642086923386149 1.0 0.467732709307765 9 Q9GZY8,P17900 2 +Cataplexy 0.5144780714222958 1.1156625352658802 0.2645666129972261 1.0 0.4678630536602428 4 O15118 1 +Raynaud phenomenon 0.5852895974589788 1.114318307402756 0.2651426557569429 1.0 0.4685259827450077 6 O75844 1 +Impaired collagen induced platelet aggregation 0.4317845516425055 1.113542936116512 0.2654753187457852 1.0 0.4688933654341033 2 Q8N5K1 1 +Poor gross motor coordination 0.5140486589221555 1.113364561308757 0.2655518887967292 1.0 0.4688933654341033 4 O75503 1 +Macrogyria 0.5700302835315023 1.111560759796122 0.266327052131984 1.0 0.4697279094399022 7 Q9H9S5,O43505 2 +Infantile axial hypotonia 0.5043556302129424 1.109032575523628 0.2674161293301331 1.0 0.4709663995368779 11 P07602,P17900,Q9NZJ7 3 +Abnormality of the clitoris 0.4103740169303078 1.1070522292083438 0.2682713475950438 1.0 0.4720846003391439 24 Q9Y5Y5,Q9Y619,P16435,P53701,P51809,P40855,O75381 7 +Abnormal cervical spine morphology 0.547766301290901 1.1062197880046736 0.2686314000104519 1.0 0.4722022394328192 5 Q8NCH0 1 +Abnormality of lipoprotein cholesterol concentration 0.4786058939637874 1.106194549026752 0.268642321703944 1.0 0.4722022394328192 14 P50402,Q8N511,Q9BTV4,Q9UJS0,Q15800,Q8WXH0,Q9Y6B6,Q10471,Q13642 9 +Asymmetric growth 0.4693019267391817 1.1053547701877 0.269005894094303 1.0 0.4726532853731593 15 P31749,P22413,Q15125,P31751 4 +Abnormalities of placenta or umbilical cord 0.4596860845995722 1.1048990322973335 0.2692033417979802 1.0 0.4726532853731593 16 P16435,Q9Y2B2,O75844,P16278,O60826 5 +Abnormal ilium morphology 0.4287112748046847 1.1043023024187766 0.2694620244114762 1.0 0.4727510771030721 19 P22413,P01889,Q7RTS9,O95831 4 +Visual impairment 0.2892449214237011 1.1027818518347303 0.2701219110873951 1.0 0.4737303696705898 305 Q15907,Q13277,P50897,O60762,Q15058,Q96CU9,P01889,Q01105,Q9H9S5,P00846,Q8IY17,O00571,O43676,P40855,O75306,Q5XKP0,P17900,P16278,Q9H061,P00403,Q9BV73,Q96AA3,P31749,P78318,Q8N183,P04439,Q9NX14,Q9GZY8,Q6P4Q7,P07602,P51798,O43505,Q2M389,Q86Y39,Q9NZ08,Q9Y287,Q9Y5Y5,O60313,Q08J23,Q9NPL8,Q8WWV3,Q8N3R9,Q86YV9,Q7LGA3,Q6P4A7,O95831,Q9Y4P3,Q71SY5,O75503,O14773,O60220,P13473,Q96A33,Q15555,P09622,O15460,Q9NZJ7,O75489,P03886,Q96N66,Q9UHX1,O43681,Q10713,O43292,P06865,P22413,Q9H6K4,Q05639,Q96S66,P53701,O75381 71 +Contractures of the joints of the upper limbs 0.3240280825805836 1.1014243358474314 0.2707120186783724 1.0 0.474408044771956 82 P07196,Q9NR77,Q9Y619,P16435,Q8WVQ1,P42892,Q969X5,Q7LGA3,O75844,Q71SY5,P50402,Q8IZA0,P35637,Q15392,Q99720 15 +Poor eye contact 0.3676790232072723 1.098836008672081 0.2718396026853273 1.0 0.4757380895591201 45 O95298,Q15907,Q8N183,Q9NPL8,O75489,P03886,Q96CU9,Q9UHX1,O43676,O75306,Q5XKP0,Q86Y39 12 +Macroglossia 0.3753067710814907 1.0974012601150749 0.2724660228206381 1.0 0.4757380895591201 37 P31749,P61978,P04066,P10253,Q9H9S5,Q7LGA3,Q9Y4P3,Q10713,P16278,Q96A33 10 +Abnormal ldl cholesterol concentration 0.4857215554130878 1.095796536539814 0.2731678245242666 1.0 0.4758473173650088 13 Q8N511,Q15800 2 +Stenosis of the external auditory canal 0.5507585195886877 1.0913332901814807 0.2751262544312773 1.0 0.4783643498099627 8 O95202 1 +Respiratory tract infection 0.2967367804676331 1.0902117379337957 0.2756198839426276 1.0 0.4785081697371448 161 P00813,Q13277,P01889,P15586,Q13510,P16278,O95721,P78318,P53634,P09601,P07602,P51798,Q8N5M9,P14174,P54802,Q9Y487,O95298,Q14C86,Q9NPL8,P04062,Q86YV9,Q9Y4P3,Q71SY5,P08236,Q8NFH4,O60220,P33991,O15460,Q9NZJ7,O95202,Q9H936,P04066,P10253,Q8N1F7,Q7RTS9 35 +Abnormality of the odontoid process 0.5650431417683057 1.0867272683377946 0.2771573592303744 1.0 0.4804611013379546 7 P16278,O95831,Q7RTS9 3 +Abnormality of pelvic girdle bone morphology 0.2961435962333554 1.0809803338638757 0.2797058617371102 1.0 0.4834396675218773 158 P00813,P61978,Q15125,P01889,Q9H9S5,Q96HY6,P16278,P31749,O75718,P16435,Q14739,Q8WVQ1,Q969X5,Q8IZA0,Q9Y487,Q8N3R9,Q7LGA3,Q9Y4P3,O95831,O75844,Q96A33,Q9Y619,O95202,Q9UHX1,P22413,Q9NVI7,Q7RTS9 27 +Abnormal erythrocyte sedimentation rate 0.5633280551581831 1.0781889870996972 0.2809494256394709 1.0 0.4838371182830373 7 P01889,P14174 2 +Brain imaging abnormality 0.3732055217917716 1.07367557695529 0.2829681113085431 1.0 0.4860123386707943 40 P31749,Q05086,Q9NZJ7,Q13501,P03886,Q969X5,Q9P0J1,P07602,O75306,P00403 10 +Enlarged thorax 0.4134214339167067 1.0716612922243909 0.2838721926416898 1.0 0.4870279380678286 20 Q32P28,Q14739,P04066,O75844,Q7RTS9 5 +Distal lower limb amyotrophy 0.4814294788817342 1.0692819456870637 0.2849426433945412 1.0 0.4875633351692515 13 Q9H0B6,Q9NR77 2 +Granulocytopenia 0.5057743559372148 1.0691046121820724 0.2850225336337209 1.0 0.4875633351692515 4 P54819,O75533,P62857 3 +Laryngomalacia 0.4343382850650545 1.0680810772995606 0.285483940767024 1.0 0.4879942004010266 18 O00192,P16435,Q9NZJ7,P21964,P07602,P54198 6 +Abnormal myocardium morphology 0.2957138387971359 1.067598479478879 0.2857016698148691 1.0 0.4880082060864174 181 Q14108,P09493,Q96CU9,P01889,P15586,Q9H9S5,P00846,Q9BT22,O43676,P40855,O75306,Q5XKP0,P16278,Q9H061,P00403,P22626,P48735,P50402,Q86Y39,Q9NZ08,P54802,Q9Y5Y5,P50416,O60313,Q9NPL8,P04062,P42167,Q9Y4P3,Q9BUB7,P08236,Q8N5M1,P13473,O75489,P03886,P10253,P53701,P22413,Q13423,Q9NVI7,Q96IX5,O75381,P06280 42 +Abnormal greater sciatic notch morphology 0.5753417718595529 1.0665391715216614 0.2861799811350811 1.0 0.4885964812612897 6 Q96HY6,Q7RTS9 2 +Abnormal aldolase level 0.5048603033176429 1.0642181802837072 0.287229872994986 1.0 0.489589198581336 4 Q9H9S5 1 +Dystonia 0.2955007530296793 1.064156308417993 0.2872578960332312 1.0 0.489589198581336 167 Q96CU9,Q9BPX6,Q6DKK2,Q01105,P00846,O75306,P17900,P35637,P16278,P51572,Q99720,O15118,P07602,P61916,Q2M389,O75208,Q08J23,Q15067,P04062,Q8NI60,Q96JX3,P61457,Q71SY5,O43464,O60220,O14949,Q9NQZ5,O00584,Q9NZJ7,O75489,Q13501,P03886,Q96N66,Q9H936,O43681,Q05639 36 +Abnormality of the calf 0.321920451465976 1.0627107854255766 0.2879131282301479 1.0 0.49022025571765 68 O75718,Q9NR77,Q9NX62,P16435,Q32P28,Q9Y619,Q8WVQ1,P51798,Q7LGA3,Q96HY6,Q9Y4P3,O95831,P22413,P08236,P16278,Q8TAB3,Q7RTS9 17 +Polycystic liver disease 0.4635879218472537 1.062642985188622 0.2879438857113547 1.0 0.49022025571765 3 Q9UGP8,P14314 2 +Abnormal renal pelvis morphology 0.3356814997032307 1.060957566403698 0.2887091858527313 1.0 0.4911641299130834 60 Q9Y5Y5,O75718,P16435,P61978,Q15125,Q8NCH0,O43505,P40855,Q71SY5,O75381,P98175 11 +Acne 0.4524985250131873 1.0564649401173614 0.2907558504448668 1.0 0.4933846088787577 16 O00192,Q92542,P01889,P21964,P22413,P54198,Q9NZ08 7 +Thoracic scoliosis 0.4788348950823879 1.053255594373228 0.2922238647904931 1.0 0.4947941701905187 13 O75844 1 +Congestive heart failure 0.3266191220233139 1.050371306929851 0.2935474323658813 1.0 0.496493805359577 65 Q70HW3,P22626,O95721,O75880,P06280,Q9BUB7,P09493,P03886,P10253,Q9Y4P3,P22413,O75306,P16278,P00403 14 +Sparse eyebrow 0.3723585388373451 1.048893025124211 0.2942273560515038 1.0 0.4972380702955187 35 Q08J23,P61978,Q15125,Q14574,O75844,Q71SY5,Q9NVI7 7 +Migraine 0.4068929455267341 1.046891018076209 0.2951498449111867 1.0 0.4981188324624302 22 O60313,P03886,P01889,P05067,Q9NZ08,P00403 6 +Long penis 0.4593305426672167 1.0381682839525823 0.299191715578154 1.0 0.5030445034364014 3 P31749 1 +Low back pain 0.4196507842557059 1.0380293272661327 0.2992564016793118 1.0 0.5030445034364014 2 Q8WVX9 1 +Genetic anticipation 0.4196507842557034 1.038029327266117 0.2992564016793191 1.0 0.5030445034364014 2 Q9UBB4 1 +Diminished motivation 0.3972692571731575 1.0373390584298603 0.2995778688888375 1.0 0.5033438619009417 26 P17900,P35637,P06865,P04062 4 +Diaphragmatic weakness 0.5340275402833141 1.0367052652331348 0.299873237433234 1.0 0.5033438619009417 5 Q9NR77 1 +Abnormal joint morphology 0.2876445450764095 1.0364752824054615 0.2999804650241509 1.0 0.5033438619009417 289 P07196,Q05086,Q14108,Q9NX62,Q96PU5,Q15125,P01889,P42892,O15269,Q9H9S5,Q96HY6,Q86XL3,Q13510,P16278,P31749,O75718,Q9NR77,P16435,Q14739,Q15041,Q8WVQ1,Q969X5,P07602,P50402,Q8IZA0,Q9NZ08,P14174,Q9Y487,P51571,P04062,P38435,O75298,P10321,Q8NCH0,Q7LGA3,Q9Y4P3,O95831,O75844,Q71SY5,Q9BUB7,P08236,O60220,Q15392,Q96A33,Q9Y619,Q9NZJ7,O15460,O95202,Q9UHX1,P22413,Q9H6K4,Q7RTS9,P06280 53 +Inappropriate behavior 0.4195503228652547 1.0362557421914005 0.3000828476811754 1.0 0.5033438619009417 19 Q9NZJ7,Q13501,P07602,Q9UNW9,P17900 5 +Abnormal cartilage morphology 0.475921100168719 1.035260864952526 0.300547101009835 1.0 0.503941107452776 13 Q9UHX1,Q7LGA3,O75874,P48735 4 +Hemianopia 0.5082827523204991 1.0343826587858365 0.3009573080426277 1.0 0.5040661535104338 10 P03886,P00403 2 +Abnormality of the umbilical cord 0.5242805838501055 1.0341405745457994 0.3010704502914962 1.0 0.5040661535104338 9 O75844,Q9Y2B2,P16435,O60826 4 +Abnormal systemic arterial morphology 0.2933971089661719 1.0337125006690415 0.3012705873441701 1.0 0.5040661535104338 153 P10619,P61978,P01889,P00846,P17900,Q13510,Q9NWM8,O15118,Q96DF8,P05067,P07602,P61916,P04062,P38435,Q8N3R9,Q7LGA3,O75844,Q9NSD9,Q9NZJ7,P03886,O75845,Q9UHX1,P10253,P22413,P06865 25 +Aplastic clavicle 0.5334352642483456 1.033711685548226 0.3012709685214787 1.0 0.5040661535104338 5 Q9Y619,P48651 2 +Pes cavus 0.298092924826167 1.0326715492304888 0.3017576321822748 1.0 0.5045179650771845 102 P07196,Q15907,O15269,Q99720,Q9NR77,Q14739,O60313,Q08J23,O75298,P04062,Q8NI60,Q8N3R9,Q7LGA3,O95831,Q96D71,Q71SY5,Q8N2K0,Q9H0B6,Q10713,Q9H6K4,Q96BR5 21 +Decreased circulating antibody level 0.3700333965404081 1.030004470977798 0.3030079067814655 1.0 0.5057058475905613 39 P09601,P00813,P14174 3 +Abnormal upper motor neuron morphology 0.5074589108147265 1.0297667333963134 0.3031195204965322 1.0 0.5057058475905613 10 Q13501,P35637,Q99720 3 +Abnormal hand bone ossification 0.5533851244642076 1.0287218249793488 0.3036104110895845 1.0 0.5058763147054819 7 Q15125,P22413 2 +Glossoptosis 0.5532198537043299 1.0279001757757014 0.3039967868763162 1.0 0.5059866915079633 7 Q9Y5Y5 1 +Pruritus 0.4006133978213748 1.0278100799467411 0.3040391737798469 1.0 0.5059866915079633 24 P00813,Q13277,Q14739,P22830,P22413,Q96A33 6 +Abnormal dermatoglyphics 0.3150678135564759 1.0275599372052953 0.3041568776776078 1.0 0.5059866915079633 77 Q9Y5Y5,P61978,O95202,Q969X5,Q8NCH0,Q9UHX1,O75381,Q9Y4P3,P40855,Q71SY5,Q9Y487,P98175 12 +Respiratory insufficiency 0.2934393535629664 1.026852769404347 0.3044897969989328 1.0 0.5063596838347123 189 Q96CU9,Q9H9S5,Q68CQ7,O43676,P40855,O75306,Q5XKP0,Q13510,P35637,Q70HW3,Q9NR77,P36551,Q14739,Q8WVQ1,Q969X5,P07602,P61916,P50402,Q86Y39,O75208,Q9Y5Y5,Q08J23,Q15067,Q92804,O95831,Q9NSD9,Q9BUB7,O43464,P33991,Q15165,Q9Y619,Q9NZJ7,O75489,Q13501,P03886,P10253,O75381,Q7RTS9,P06280 39 +Weakness of long finger extensor muscles 0.457012528327828 1.0248527846173754 0.3054326558107179 1.0 0.507591731292858 3 P31483 1 +Telangiectasia 0.3678965561413816 1.021243207765359 0.3071392260039438 1.0 0.5096738563328715 40 P10619,P31749,P03886,P00846,P22413,O75306,Q8IZA0,P06280 8 +Aplasia involving bones of the extremities 0.4561870929544203 1.0201131519130482 0.3076747999742397 1.0 0.5101489209702312 3 P02545,Q8NCM8 2 +Muscle fibrillation 0.4468540099107361 1.0184320472870918 0.3084726787753196 1.0 0.5109764358945372 16 Q13510,O95831 2 +Distal muscle weakness 0.3124188090945306 1.017846208846914 0.3087510481890743 1.0 0.5112557349679019 71 P07196,P22626,P31483,Q9NR77,P36551,Q9BQT8,O15269,P00846,O95831,Q71SY5,Q96BR5,P35637,Q99720 13 +Epispadias 0.5651200680472268 1.0175025476882045 0.3089144209138781 1.0 0.5113444820955381 6 P53701,Q9Y619,P48651 3 +Slurred speech 0.5207687160123656 1.015271732712306 0.3099763150385597 1.0 0.5126683164964019 9 Q9Y487 1 +Dyschromatopsia 0.5503339815303551 1.0135568496359493 0.3107942564043482 1.0 0.5137259213383443 7 Q9H061,Q9H6K4 2 +Duplication of hand bones 0.3233496869946712 1.0086035209137778 0.3131648180759534 1.0 0.5164110084454766 65 O43924,Q7Z4L5,O00192,Q15067,Q14739,Q15125,O95202,Q8WVQ1,O75845,P21964,Q8WXW3,Q9UHX1,Q8IY17,P54198,Q10713,Q9Y263,O60826,P98175 18 +Thoracic hypoplasia 0.3692543488311444 1.0039915373738555 0.3153826926393501 1.0 0.519283344755777 33 O75718,P16435,P04062,Q14739,Q8WVQ1,Q9UHX1,P51798,Q96HY6,Q96A33 9 +Neoplasm of the male external genitalia 0.4860155102690128 1.001637780624789 0.3165185669780712 1.0 0.5203810715365251 11 P31749,Q01844,Q13423 3 +Functional abnormality of the gastrointestinal tract 0.2858198022455647 1.0000665901464811 0.3172782832038925 1.0 0.5203810715365251 292 Q05086,Q14108,Q96PU5,P61978,P55795,P01889,P42892,Q01105,O15269,P15586,P00846,O75874,O75306,Q13510,P35637,Q99720,P00403,O15118,Q9NR77,P16435,P36551,Q14739,Q9GZY8,P05067,P07602,P61916,P48735,Q8IZA0,Q9NZ08,Q9Y5Y5,O60313,P51571,Q15067,P04062,Q9Y4P3,Q96D71,Q9NSD9,O60220,Q96A33,Q9Y619,Q9NZJ7,O15460,O95202,P03886,O75489,Q13501,Q9H936,Q9UHX1,P22413,Q01844,Q05639,P08183,P06280 53 +Hypokinesia 0.4618283861028159 0.999640316314227 0.317484605011324 1.0 0.520536180972456 14 P04062 1 +Aspiration 0.5014595564295092 0.9961710114828942 0.3191670616753872 1.0 0.5229265470573174 10 P06865 1 +Anteriorly placed anus 0.4695487247014886 0.9959271533599592 0.3192855409861765 1.0 0.5229367264112554 13 P16435,Q9NX14,Q9Y2B2,P48651,P53701 5 +Heinz bodies 0.4122521456052179 0.9921008529571472 0.3211483305038607 1.0 0.5252489197636879 2 O14936 1 +Epiphyseal dysplasia 0.5592798082584818 0.989526198888468 0.3224057581752537 1.0 0.5271204006950972 6 Q9HC07,Q7RTS9 2 +Hypertriglyceridemia 0.3995318845464054 0.9887268067804394 0.3227968234938765 1.0 0.5275745978366585 22 P50402,P22830,O95470 3 +Aphasia 0.356753599637312 0.985382556336874 0.3244361946862104 1.0 0.5295107900660014 45 P22626,O00192,P31483,Q9NX14,Q13501,P03886,O96008,Q8N3R9,P05067,O75648,P53701,Q7LGA3,Q9H9P8,P54198,P00403 15 +Patchy changes of bone mineral density 0.4900376828191147 0.9851068076736854 0.3245716097916387 1.0 0.5295462551346596 4 Q14739,Q13501 2 +Difficulty standing 0.5582066374370322 0.984389515145146 0.3249240312988912 1.0 0.5297924075947072 6 Q7RTS9 1 +Abnormal aortic valve physiology 0.3643350210658874 0.9823355230691772 0.3259345795163988 1.0 0.5309307456698229 38 P04062,Q15125,P01889,Q9UHX1,Q9Y4P3,O75844,P16278,Q9NZ08 8 +Hyperkeratosis 0.3227751182900298 0.9794821327329868 0.3273418126347904 1.0 0.532387626834097 64 P51648,P31749,Q9NWM8,O95721,P16615,P53634,P04062,P09493,P98194,P04066,O15269,P22413,Q14574,O75844,P06280 15 +Impaired pain sensation 0.4219349675348642 0.9790140228997316 0.3275730508012122 1.0 0.5325777558925119 18 P07196,O95831,Q9NR77,O15269 4 +Abnormality of the vertebral endplates 0.5432892518225634 0.978579115658767 0.3277879824476848 1.0 0.5327412499097404 7 P51798,P22413,Q7RTS9 3 +Bladder neoplasm 0.5138779015678597 0.9782842007776724 0.3279337817695364 1.0 0.5327923109461112 9 P31749,P25054,Q07812,P35222 4 +Color vision defect 0.4407666619897686 0.9774367873631356 0.3283529581308457 1.0 0.5332354579821248 16 O60313,Q6P4Q7,Q9H6K4,O43464,O60220,Q9H061 6 +Aplasia hypoplasia of the phalanges of the toes 0.5222156398104152 0.9770783145940743 0.3285303826343044 1.0 0.5332354579821248 5 P35453,Q9ULC3,Q9Y2B2,P02545 4 +Abnormality of somatosensory evoked potentials 0.5220860659576858 0.976425231991034 0.3288537827329807 1.0 0.5332354579821248 5 O60220,Q9NQZ5 2 +Loss of ability to walk 0.4579045686642085 0.974746095410738 0.3296862217347851 1.0 0.5339690226143041 14 P00846,Q96D71 2 +Aspiration pneumonia 0.3874033920728911 0.9747389611292868 0.3296897614939327 1.0 0.5339690226143041 27 O95721,P78318,P04062,Q6NUK1,P16278,P06753,P20700,Q13510,O60220 9 +Progressive cerebellar ataxia 0.3641254223219509 0.9703741674230252 0.3318600202357831 1.0 0.5365945426931158 35 Q9Y619,O75489,O14773,Q8NI60,Q96CU9,O75306,P35637,Q9Y487 8 +Aplasia hypoplasia of the femur 0.4571426712517142 0.9699144294685712 0.3320891469825715 1.0 0.5367353388774525 14 Q9UHX1,Q96HY6,Q8WVQ1,O95831 4 +Generalized abnormality of skin 0.287225057095526 0.9691848830261288 0.3324529521272135 1.0 0.5368310138351203 233 P10619,P00813,P51648,Q14108,Q15125,P07858,P01889,O15269,P00846,P40855,O75306,P16278,P00403,Q9NWM8,O15118,P31749,P36551,Q14739,P22830,P61916,Q8IZA0,Q9Y487,Q9Y5Y5,Q08J23,P04062,P38435,P98194,Q8NCH0,Q86YV9,Q9Y4P3,O75844,P98175,P03886,P00374,P04066,P22413,O75381,P06280 38 +Upper limb amyotrophy 0.4301467280634696 0.9685440349988772 0.3327727380620082 1.0 0.5368310138351203 17 P07196,Q9BQT8,P31483,Q9NR77 4 +Hypoparathyroidism 0.4483313460809865 0.9682776716836106 0.3329057129210331 1.0 0.5368310138351203 15 Q08J23,O00192,Q96DF8,P03886,P54198,P00403 6 +Metaphyseal widening 0.3999443232950794 0.967962463762515 0.3330631164730238 1.0 0.5368310138351203 20 Q14739,Q8WVQ1,Q96HY6,O95831,P16278,Q7RTS9 6 +Abnormally lax or hyperextensible skin 0.3583228571974787 0.9677400835566112 0.3331741940844972 1.0 0.5368310138351203 43 Q9NWM8,Q15555,P04062,P38435,Q8NCH0,Q9UHX1,Q9Y4P3,P22413,Q9Y487 9 +Cerebral calcification 0.3653685192478078 0.967567258423952 0.3332605357364633 1.0 0.5368310138351203 33 O60313,O00584,P03886,O75845,P05067,P22413,Q16625,Q9NSD9,P00403 9 +Epileptic spasm 0.3107058932127567 0.9665574573305338 0.3337653105902731 1.0 0.5370220437752996 70 P13073,Q08J23,Q9GZY8,Q9UBX3,Q96N66,P03886,Q01105,P00846,Q2M389,Q71SY5,Q05639,Q13510 12 +Abnormal diaphysis morphology 0.3088774227291501 0.9638248047569156 0.3351337684315423 1.0 0.538489086612365 75 Q9NX62,P48651,Q96HY6,P16278,O75718,Q9NR77,P16435,Q14739,Q8WVQ1,P51798,Q9Y487,Q32P28,Q7LGA3,Q9Y4P3,P08236,Q9Y619,Q9HC07,P22413,Q7RTS9 19 +Progressive spasticity 0.4474020482518941 0.9622108614371928 0.3359436942783835 1.0 0.5392311221221922 15 O60313,P07602,P17900,Q9NZJ7 4 +Abnormal protein glycosylation 0.4284517031054456 0.956773511747176 0.3386815846167277 1.0 0.5421394653553591 17 Q96AA3,O60762,P51571,Q8N511,O75340,Q9BT22,Q9H0U3,Q2TAA5,Q9Y487 9 +Abnormal circulating carbohydrate concentration 0.3612238827396043 0.955257124594383 0.339447684001344 1.0 0.5427900144449916 40 Q70HW3,Q9BWD1,P03886,P22695,O95831,O43676,Q86Y39 7 +Ophthalmoparesis 0.3097518969885086 0.953703706400771 0.3402336435094251 1.0 0.543487075262998 77 O60313,P31749,Q15555,O15460,P04062,O75489,P03886,Q96CU9,Q9BPX6,P01889,Q9GZY8,P00846,Q10713,O75306,P00403 15 +Oral pharyngeal dysphagia 0.4622797266833365 0.95111240793621 0.3415473166733527 1.0 0.5448381510494784 13 Q13510,Q05639 2 +Generalized hyperpigmentation 0.4698218441401312 0.9499801862357145 0.3421223204442354 1.0 0.54556856166698 12 P51648,Q13423 2 +Abnormal 2nd finger morphology 0.5231507518575922 0.9488469161092434 0.3426984763225298 1.0 0.5459266425137975 8 Q71SY5,Q9H6K4 2 +Abnormal circulating proline concentration 0.5164174798000087 0.9478805112660188 0.3431902873811319 1.0 0.5463364178473384 5 Q9P0J1,P20674 2 +Abnormal mitral valve physiology 0.3607311127685631 0.947159449063079 0.3435575352438875 1.0 0.5467341985534773 38 P04062,P09493,P01889,Q9Y4P3,O75844,O75306,Q9NZ08,P06280 8 +Abnormality of subcutaneous fat tissue 0.4266716859845512 0.9444170174890564 0.3449565886729284 1.0 0.54802448500631 17 Q9Y487 1 +Insulin resistant diabetes mellitus 0.549603042083965 0.9432635460165336 0.3455461169865101 1.0 0.5480750335270167 6 O75844 1 +Abnormality of the fontanelles or cranial sutures 0.2932696102878278 0.9432036974904258 0.3455767225137072 1.0 0.5480750335270167 119 Q9NX62,P61978,Q15125,P20674,P48651,Q9BT22,P40855,P31749,O75718,P16435,P51798,Q9Y487,Q9Y5Y5,Q08J23,Q32P28,Q8NCH0,O95831,O75844,P98175,Q9Y619,O75845,P22413,O75381 23 +Coarse facial features 0.3088350585401181 0.9413171758461653 0.3465423433788701 1.0 0.5490940580289957 70 P10619,Q7RTS9,P61978,P04066,P15586,Q7LGA3,Q9Y4P3,O95831,P16278,P38159,Q96A33,P54802,P06280 13 +Abnormal thorax morphology 0.2841334130562719 0.9383686477122576 0.3480549922962603 1.0 0.5506929871317869 245 P07196,P00813,P51648,P61978,Q15125,P55795,P15586,Q96HY6,Q13510,P16278,P31749,O75718,P16435,Q14739,Q8WVQ1,P50402,P54802,Q9Y487,O60313,Q08J23,Q32P28,P04062,Q8N3R9,Q8NCH0,Q7LGA3,Q9Y4P3,O95831,O75844,Q71SY5,Q9NSD9,P08236,Q96A33,P98175,Q15555,Q9Y619,O95202,P04066,O75845,Q9UHX1,P22413,Q9NVI7,Q7RTS9 42 +Titubation 0.4893630539204049 0.9285700524486504 0.3531119479558078 1.0 0.5566143666931143 10 Q5T8D3,P35637,Q99720,Q5JRX3 4 +Limb joint contracture 0.2924254982336958 0.9273490473321132 0.3537453363685301 1.0 0.5572356363897915 110 P07196,P42892,Q9H9S5,Q86XL3,P35637,Q99720,Q9NR77,P16435,Q8WVQ1,Q969X5,P50402,Q8IZA0,O60313,Q08J23,Q7LGA3,O75844,Q71SY5,Q15392,Q8N2K0,Q9Y619 20 +Retinal atrophy 0.3720069063799261 0.9257004133556864 0.354601693008012 1.0 0.5582070584762825 30 P51648,P04062,Q9H9S5,Q7LGA3,Q10713 5 +Central nervous system cyst 0.3258791741248603 0.924910532403335 0.3550124475338894 1.0 0.5586648583151543 59 Q15125,O95202,Q9UHX1,Q9H9S5,P00846,Q9Y487 6 +Abnormal posterior segment imaging 0.4786229381017914 0.924426451096414 0.3552643282478733 1.0 0.558797946152854 4 Q96S66 1 +Chordee 0.532290697173819 0.9241033384471282 0.3554325153176838 1.0 0.558797946152854 7 P53701,P16435,P48651 3 +Abnormality of cranial sutures 0.2928791437037821 0.923595713647121 0.3556968463596419 1.0 0.558797946152854 95 P31749,O75718,Q32P28,Q9Y619,Q9NX62,P61978,P16435,Q8NCH0,O75845,P22413,O75381,O95831,O75844,P40855,Q9Y487,P98175 16 +Abnormal oral physiology 0.3282705958375018 0.92303000436368 0.3559915692736328 1.0 0.559072397058861 57 Q05086,Q9NR77,Q92804,O15460,Q14739,Q13501,P55795,P01889,P15586,Q68CQ7,P35637,Q8TAB3,Q15165 13 +Micromelia 0.3831607316334751 0.919359683167783 0.3579074698172095 1.0 0.5613242405416035 26 O75718,Q9UHX1,Q96HY6,O75874,P48735,Q15392 6 +Decreased specific antibody response to vaccination 0.4004143237644365 0.918909415810743 0.3581429545350865 1.0 0.5615045042828788 2 P50851 1 +Adducted thumb 0.3804369160978029 0.9155974714783176 0.3598780580310081 1.0 0.5636933416408251 27 Q71SY5,P42892,Q8NCH0,Q86XL3 4 +Bifid tongue 0.4769489554862404 0.9155516443721684 0.3599021034864349 1.0 0.5636933416408251 4 P61978 1 +Adrenal insufficiency 0.3592684984266382 0.9103704109151696 0.3626271968493626 1.0 0.5670082185043072 33 Q9Y5Y5,P31749,O95470,Q13423,P40855,P33991,O75381 7 +Blue sclerae 0.3894475062790064 0.9090878505030688 0.3633037552495182 1.0 0.5674945982401931 22 O75718,Q8WVQ1,Q8NCH0,P22413,Q96EK5 5 +Emg myopathic abnormalities 0.3700912641137375 0.9086310724043188 0.3635448990885135 1.0 0.5676809051137433 30 P07196,P46976,P22626,P12235,Q7Z406,P31483,P09651,Q9BTV4,Q13501,Q9H9S5,P06753,Q9Y6B6,P50402,P13473 14 +Upper limb muscle weakness 0.3793920147546603 0.9067292809404504 0.3645499752155294 1.0 0.5684141162848433 27 P07196,P31749,P36551,P00846,P50402 5 +Spastic gait 0.3873493255093148 0.9054926436650704 0.365204455327351 1.0 0.5689372417775255 23 Q15041,Q9Y619,O75298 3 +Hemolytic anemia 0.362133796607138 0.9035934221034662 0.3662110305182922 1.0 0.5703146038629907 32 P00813,P48637,P09601,P22830,Q9H0P0 5 +Metatarsus adductus 0.4296709377803183 0.9028355334144134 0.36661318929323 1.0 0.5707500787860513 16 O95202,Q08J23,Q15392 3 +Contractures involving the joints of the feet 0.3886214112647924 0.9025698934493076 0.3667542110849591 1.0 0.5707788557413095 22 O60313,Q9H9S5,P50402,Q8IZA0,Q8N2K0 5 +Infantile muscular hypotonia 0.3038762176944599 0.8944711355970182 0.3710698667434919 1.0 0.5753386464961132 75 P17900,Q9NZJ7,Q9GZY8,P03886,Q9H936,P16278,P10253,Q9H9S5,P00846,P07602,O75306,Q13510,Q9Y487 13 +Ectopic anus 0.4282259645781806 0.8931376050529982 0.37178348684838 1.0 0.5759120325040753 16 P16435,Q9NX14,Q6NUK1,Q9Y2B2,P48651,P53701,O60826 7 +Recurrent viral infections 0.444945605639487 0.8926961330670992 0.3720199217574467 1.0 0.5760867006470035 14 P00813 1 +Abnormal circulating pyruvate family amino acid concentration 0.3871435931492112 0.8909130531870013 0.3729758169940376 1.0 0.5771831746040622 22 O75880,P03886,P22695,P20674,Q9P0J1,P00846,Q9BUB7,Q5XKP0,O75208 9 +Bone marrow foam cells 0.4717531797608032 0.8880521290549632 0.3745127112019086 1.0 0.5786302077536839 4 O15118 1 +Joint contracture of the hand 0.3228269636334416 0.8880162610737091 0.3745320043747009 1.0 0.5786302077536839 59 P07196,Q9NR77,P16435,Q9Y619,Q8WVQ1,P42892,Q71SY5,O75844,Q8IZA0,Q15392 10 +Macular purpura 0.4272769277277241 0.8867708519518501 0.375202283572289 1.0 0.579473553342083 16 P38435,Q16625,Q8NCH0,P04062 4 +Increased megakaryocyte count 0.4319123741859126 0.8813993006966746 0.3781017360397545 1.0 0.5831781081037009 3 P04637,O75533 2 +Hyperconvex fingernails 0.5364627482010783 0.880688230134219 0.3784865889666311 1.0 0.5835784612401747 6 O95202 1 +Happy demeanor 0.5027573999741952 0.8793512208286048 0.3792108716835061 1.0 0.5839597684047629 5 Q15907 1 +Follicular hyperkeratosis 0.5094285104510976 0.8784135821529017 0.3797193162363133 1.0 0.5845117564536508 8 Q9NWM8 1 +Reduced forced expiratory volume in one second 0.392719739567927 0.8716002687377745 0.3834264840312942 1.0 0.5888561037315425 2 Q96J02 1 +Decreased cervical spine flexion due to contractures of posterior cervical muscles 0.5342368968003799 0.8701233233384053 0.3842330129920419 1.0 0.5895116516854187 6 P50402,Q13642,Q9BTV4 3 +Abnormal cornea morphology 0.2852748235533791 0.8694643093684942 0.3845932213853953 1.0 0.5898700115947222 167 P10619,P51648,Q15125,P01889,Q9H9S5,P40855,Q13510,P16278,Q9NWM8,P31749,Q14739,Q96DF8,O43505,Q9NZ08,Q9Y5Y5,P04062,Q8N3R9,Q8NCH0,Q7LGA3,Q9Y4P3,Q16625,O75844,Q71SY5,P08236,Q96EK5,Q15555,O95202,P04066,O75845,Q9NVI7,O75381,P06280 32 +Increased blood pressure 0.3043889409568248 0.868114535947799 0.3853316342601875 1.0 0.59041932644209 78 P06280,P16435,P04062,P36551,P03886,P01889,P42892,Q10713,P22413,Q9Y4P3,O75844,Q9NSD9,P00403 13 +Hemoptysis 0.5002740413864473 0.8669402270654728 0.3859747610069144 1.0 0.5908739789520975 5 P01889 1 +Preaxial hand polydactyly 0.4628763147152237 0.8667234099195346 0.3860935756073851 1.0 0.5908739789520975 11 O95202 1 +Abnormality of the autonomic nervous system 0.3179517897692317 0.8616108688309613 0.3889016879893081 1.0 0.594520532541581 61 P42892,Q9Y2B2,O15269,P07686,P07602,P0DP25,O00192,Q15067,P04062,Q8WXW3,P54198,O76024,O43464,Q96EK5,Q9NZJ7,O43681,Q10713,P20700,P06280 19 +Cyanosis 0.3959437738778832 0.8611421475763603 0.3891597583213118 1.0 0.5945248128109775 19 P04066,P22413,O75844,Q8TAB3,P98175 5 +Tinnitus 0.4398078390496206 0.8602676935965146 0.3896414970100426 1.0 0.5946756530382629 14 Q9NR28,O95831,Q9NR77 3 +Limb tremor 0.5311297074525126 0.8553946375893643 0.3923327112681822 1.0 0.5978036536104655 6 Q05086,Q9NR77 2 +Focal cortical dysplasia 0.4271758436944933 0.8545413854862177 0.3928050888094709 1.0 0.5983276990433342 3 P49815,P42345 2 +Disproportionate tall stature 0.3565913726991826 0.8525151267968336 0.3939282469003708 1.0 0.5998423583072662 32 P31749,Q9NWM8,O95202,Q8N3R9,Q8NCH0,Q7LGA3 6 +Deviation of the 2nd finger 0.53036357920395 0.8517666836171444 0.3943436011910641 1.0 0.6002785929241754 6 Q71SY5,Q9H6K4 2 +Abnormal lumbar spine morphology 0.4754465101446237 0.8511516006758287 0.3946851444793688 1.0 0.600602222471382 10 O75845,P04062 2 +Pleural effusion 0.452752103735381 0.8479802950660985 0.3964489447893773 1.0 0.6024885251502862 12 Q14739,P01889,P14174 3 +Abnormality of bladder morphology 0.4748397454717223 0.8477875355507068 0.396556305947207 1.0 0.6024885251502862 10 Q9NWM8,P16435 2 +Diplopia 0.3816672129252725 0.8477603464431422 0.3965714508610514 1.0 0.6024885251502862 22 O14773,O43464,P01889,P04062 4 +Eeg with spike wave complexes 0.4296025090730933 0.8463289715529344 0.3973692501267782 1.0 0.6033070296905259 15 Q14108,Q9NQZ5,O75503 3 +Abnormal corneal epithelium morphology 0.4201499867844533 0.8390375395159156 0.4014482443164988 1.0 0.6075049418611577 16 P51648,Q14739,P01889,O75844,Q9NZ08 5 +Adrenocortical adenoma 0.3870967741935562 0.8371970674104623 0.4024818056211932 1.0 0.6075049418611577 2 P25054 1 +Parathyroid hyperplasia 0.3870967741935553 0.8371970674104575 0.4024818056211958 1.0 0.6075049418611577 2 P49815 1 +Pancreatic endocrine tumor 0.3870967741935553 0.8371970674104575 0.4024818056211958 1.0 0.6075049418611577 2 P49815 1 +Galactorrhea 0.3870967741935553 0.8371970674104567 0.4024818056211963 1.0 0.6075049418611577 2 O00170 1 +Premature pubarche 0.3870967741935553 0.8371970674104567 0.4024818056211963 1.0 0.6075049418611577 2 O00170 1 +Decreased libido 0.3870967741935553 0.8371970674104567 0.4024818056211963 1.0 0.6075049418611577 2 O00170 1 +Proportionate tall stature 0.3870967741935553 0.8371970674104567 0.4024818056211963 1.0 0.6075049418611577 2 O00170 1 +Reactive hypoglycemia 0.3870967741935552 0.8371970674104567 0.4024818056211963 1.0 0.6075049418611577 2 P00367 1 +Abnormal sharpey fiber morphology 0.5271067722640619 0.8363612054968509 0.4029517302893599 1.0 0.6078203237331083 6 P22413 1 +Lewy bodies 0.5264657720787735 0.8333324575397674 0.4046572557206795 1.0 0.6096033302545038 6 P04062 1 +Hyperactive patellar reflex 0.5004636138277211 0.8326314977169706 0.4050525892255623 1.0 0.6100016038191624 8 Q15041 1 +Areflexia 0.289678009211695 0.8313056165787068 0.4058010024856631 1.0 0.6107337866165489 94 P07196,P05023,P61978,O15269,Q9H9S5,Q13510,O95721,Q9NR77,Q9BQT8,Q15041,Q969X5,O43505,O60313,Q15067,O95831,Q71SY5,Q13501,P10253,Q9H6K4 19 +Abnormal sclera morphology 0.3644657165182614 0.8276326733324466 0.4078785585958311 1.0 0.6130120832524364 29 P31749,O75718,Q8WVQ1,Q8NCH0,P22413,Q96EK5 6 +Abnormal epidermal morphology 0.3774677176628117 0.8265384393080597 0.4084987221555338 1.0 0.6133717844037718 23 P31749,P16615,P98194,P01889,P22413,Q14574,O75844 7 +Foot dorsiflexor weakness 0.3482638741680143 0.8263470225089689 0.4086072664244105 1.0 0.6133717844037718 36 P07196,P31483,Q9NR77,Q14739,Q9BQT8,Q13501,O15269,Q96BR5,Q99720 9 +Abnormality of the phalanges of the toes 0.378537190293626 0.8231351980596908 0.4104311146897774 1.0 0.6156207229378755 22 Q8WVQ1,Q9H936,Q7LGA3,O75844,Q71SY5 5 +Venous insufficiency 0.511440445504968 0.821494125869631 0.4113648686624815 1.0 0.6163195748568153 7 O00192,P54198,P04062 3 +Varicose veins 0.511440445504968 0.821494125869631 0.4113648686624815 1.0 0.6163195748568153 7 O00192,P54198,P04062 3 +Abnormal iris pigmentation 0.375137749220093 0.821074695038483 0.4116037228404787 1.0 0.6164791450131673 24 Q9Y5Y5,P31749,Q86YV9,Q9Y4P3,P40855,O75381 6 +Progressive leukoencephalopathy 0.4206631142688073 0.8177628562045131 0.4134926112376149 1.0 0.6180088973509724 3 Q9Y263,Q5JTZ9 2 +Subarachnoid hemorrhage 0.3838413731873406 0.8173547731443062 0.4137257137140615 1.0 0.6180088973509724 2 Q6YHK3 1 +Abnormality of muscle size 0.2824198841237505 0.8171866445016813 0.413821773652705 1.0 0.6180088973509724 200 P07196,P61978,Q6DKK2,O15269,Q9H9S5,Q68CQ7,Q13510,P35637,P16278,Q99720,Q9NWM8,P31749,P22626,Q9NR77,Q9BQT8,Q969X5,O43505,P50402,Q9Y487,O60313,Q92804,O75298,Q7LGA3,Q6P4A7,O95831,Q9Y4P3,Q71SY5,Q96A33,Q15165,Q8N2K0,P31483,Q9H0B6,P04066,P10253,Q10713,Q9NVI7,Q96BR5,O14979 38 +Abnormality of the tonsils 0.4835936040790567 0.8167324119123799 0.4140813644636489 1.0 0.6180088973509724 9 P00813,O00192,P54198,P31751 4 +Motor polyneuropathy 0.4542189702898175 0.8165812890628876 0.4141677514911743 1.0 0.6180088973509724 11 P07196,Q15041 2 +Ectropion 0.4542039951033804 0.8164947712269831 0.4142172128659802 1.0 0.6180088973509724 11 P04062 1 +Joint subluxation 0.4896993263727163 0.8142928036341206 0.4154772313445827 1.0 0.6192937419529811 5 Q9UHX1 1 +Abnormality of the dorsal column of the spinal cord 0.4197750148016621 0.8127625178315683 0.4163542294069349 1.0 0.620288389848778 3 Q6PI48,Q8WVX9 2 +Distal sensory impairment 0.3413111861400001 0.8089375116254859 0.4185510906965501 1.0 0.6226799682096873 44 P07196,Q9NR77,O15269,O95831,Q71SY5,P54802,Q8N2K0 7 +Hypoplasia of the iris 0.5085028667986581 0.8071298969192681 0.4195916491055356 1.0 0.6238295249069853 7 O95202 1 +Cortical dysplasia 0.3466638443057132 0.8037774935502914 0.4215254900801208 1.0 0.6257060971297651 35 O95721,Q08J23,Q96PU5,Q96N66,O43505,Q2M389,Q71SY5 7 +Sclerosis of skull base 0.4179139475637548 0.8022964501661097 0.4223814953508307 1.0 0.62617855039598 3 Q14739 1 +Tetraplegia 0.4372696764591168 0.7977830425314154 0.4249964035339781 1.0 0.6288542718110769 13 P51572,O95831,Q13423 3 +Atrophy degeneration involving the spinal cord 0.4935550171022834 0.7975104643169005 0.4251546279014917 1.0 0.6288886175818191 8 P07196,Q8IY17 2 +Hypoketotic hypoglycemia 0.4934137760546826 0.7967940751752947 0.4255706366466949 1.0 0.6291044193907663 8 O43772,P50416,P31751 3 +Chorioretinal coloboma 0.5062956440821162 0.7963549895233761 0.4258257320619254 1.0 0.6292818083580104 7 P31749,Q10713 2 +Cardiac arrest 0.3450483786400821 0.7952426726381469 0.4264723535787589 1.0 0.6298377371496064 40 Q9H0U9,P31749,P50402,P50416,O15460,Q9NX14,O95677,P04062,Q9BTV4,P01889,Q9Y4P3,P22413,O43772,Q13642,P0DP25 15 +Fetal distress 0.3639717229186885 0.7947390899503595 0.4267652887475075 1.0 0.6300705911207258 28 Q8N183,Q9NPL8,O75489,P03886,Q96CU9,P22413,O43676,Q9NVI7,O75306,Q86Y39 10 +Retinal hemorrhage 0.5059011019374384 0.7944306595339878 0.4269447613111581 1.0 0.6301358359275584 7 Q9Y487 1 +Status epilepticus 0.3225388806014071 0.7903069968349314 0.4293485015973179 1.0 0.6326714219114216 53 P05023,Q9NZJ7,P42892,Q01105,P53701,P07602,Q3ZCQ8,O43292,Q05639,Q13510,Q15392,Q9Y487 12 +Unusual infection 0.2808432834069513 0.7900857685073965 0.4294776805676072 1.0 0.6326714219114216 205 P00813,Q13277,P01889,P15586,Q9H9P8,Q9BT22,Q13510,P16278,P31749,P78318,P53634,P09601,Q14739,Q96DF8,P07602,P51798,Q8N5M9,Q9NZ08,P14174,P54802,Q9Y487,O95298,Q08J23,Q9NPL8,P04062,Q96JX3,Q86YV9,Q9Y4P3,Q71SY5,Q9NSD9,Q9BUB7,P08236,P33991,Q96A33,O15460,Q9NZJ7,O95202,Q9H936,P04066,P10253,Q13423,Q7RTS9 42 +Lumbar hyperlordosis 0.3752218975076972 0.7870560971721698 0.4312490281237666 1.0 0.6346786644551359 21 Q9H9S5,Q7RTS9,P04066 3 +Abnormality of the adrenal glands 0.3089636543246742 0.7855366012654337 0.4321390193057239 1.0 0.6352426070031835 63 Q9Y5Y5,P31749,O95470,P22413,O75874,P40855,P48735,O75844,Q13423,P33991,O75381 11 +Abnormality of urine homeostasis 0.2807851829979229 0.784581128206913 0.4326991983694559 1.0 0.6354047940775358 200 Q14108,P01889,P15586,Q9H9S5,P00846,Q9H9P8,Q5XKP0,P16278,P00403,O95721,O75880,P36551,P09601,Q9BQT8,P48735,Q4J6C6,P54802,Q14C86,P53985,P04062,Q96JX3,Q9Y4P3,Q3ZCQ8,P61457,Q9BUB7,P08236,O43464,Q8NFH4,Q8N5M1,O95470,P48637,Q9Y619,P03886,P04066,P10253,P22413,Q8N1F7,Q13423,Q9H6K4,Q9H0P0,Q9NVI7,P06280 42 +Gait imbalance 0.3747257211432448 0.7832192058132822 0.4334983984970733 1.0 0.635979697700588 21 O43464,Q9Y4P3,Q9NR77,O15269 4 +X linked recessive inheritance 0.3218302941869704 0.7822229042144883 0.4340835861254843 1.0 0.6364775019797237 53 P51571,P06280,P78318,Q15125,Q96D09,O60220,O00571,O95831,Q9H0U3,P50402,P51572,P38159,P98175 13 +Weak cry 0.4481928863134794 0.7818348174207459 0.434311656236277 1.0 0.6364775019797237 11 Q13510,O75208 2 +Macular atrophy 0.5025084131420124 0.7779052518747346 0.4366248719294956 1.0 0.6391573392355722 7 P04062 1 +Proportionate short stature 0.3430929674071776 0.7766248944116328 0.4373801097618055 1.0 0.6394590556404552 36 P10619,Q9Y619,Q14739,Q8WVQ1,P48651,P53701,Q96HY6,Q8IY17,P16278,Q15392,Q7RTS9 11 +Shallow orbits 0.4759249775365524 0.7762266404403414 0.4376151789947817 1.0 0.6396019779597406 9 O75844 1 +Autoimmunity 0.3436519814708623 0.7750959155022128 0.4382829849607521 1.0 0.6401762759320111 35 P00813,Q8IZA0 2 +Abnormality of the pulmonary veins 0.513927145203446 0.7743337682486758 0.4387334393727506 1.0 0.6404325793162873 6 O75718 1 +Abnormal bronchoalveolar lavage fluid morphology 0.3764427345368527 0.7724934058425376 0.4398222509598917 1.0 0.6418208160937267 2 P56192 1 +Abnormality of the metaphysis 0.3154115274686099 0.7703990816294238 0.4410631980245312 1.0 0.6426250786356792 57 P00813,Q9UG56,Q14739,Q8WVQ1,P48651,P51798,Q9HC07,Q96HY6,O95831,O75874,P48735,P16278,Q7RTS9 13 +Capillary malformation 0.4247632909990334 0.7658109797202329 0.4437887801512632 1.0 0.6453849946751745 14 Q9UHX1,Q71SY5 2 +Tibial bowing 0.5117078783151087 0.763945283879503 0.4448998500206058 1.0 0.6461937952591151 6 Q32P28,Q7RTS9 2 +Upper limb spasticity 0.4990996593317218 0.7613431947431935 0.4464521070934983 1.0 0.6478423410721232 7 P35637 1 +Sparse eyelashes 0.372817758412522 0.7601537633700064 0.4471626789891059 1.0 0.6484694142998927 20 Q15125 1 +Lipodystrophy 0.3426137309456286 0.7593651354814441 0.4476341633870979 1.0 0.6487492013245495 34 P09493,P04066,O75844,P50402,Q9Y487 5 +Hallux valgus 0.3997704751976173 0.7586539157499881 0.4480596112189441 1.0 0.6489619617717169 17 P31749,P04062,Q9Y4P3,Q96J02,Q15233 5 +Distal arthrogryposis 0.4782098403544321 0.7575316499025696 0.4487314116306544 1.0 0.6493216613628808 5 Q8NCH0 1 +Subcutaneous hemorrhage 0.3376383535624279 0.7570869666265355 0.4489977618985485 1.0 0.6493216613628808 43 Q9NWM8,Q14108,P04062,P38435,Q8NCH0,Q86YV9,P51798,P22413,Q16625,P49257 10 +Synostosis involving digits 0.4467274661601226 0.7568888592497486 0.4491164504072329 1.0 0.6493216613628808 4 P48651 1 +Distal joint laxity 0.4097098875073994 0.7563770718537534 0.4494231507586792 1.0 0.6493216613628808 3 O75340,Q9H553 2 +Abnormal muscle fiber protein expression 0.498018009568708 0.756096958123267 0.4495910656304862 1.0 0.6493628476610247 7 P50402,Q9H9S5,Q13642,Q9BTV4 4 +Low frustration tolerance 0.4581021983980033 0.7554873881316583 0.4499565967847838 1.0 0.6496893452645763 10 P04062 1 +Focal white matter lesions 0.4842900481380279 0.7506728971245834 0.45284953800684 1.0 0.6521344806067996 8 P12235,O00584,Q9P0J1 3 +Abnormality of the knee 0.2803741971695345 0.7501073335474377 0.4531900630580099 1.0 0.6521344806067996 101 Q9NX62,Q96PU5,Q15125,P48651,Q96HY6,Q86XL3,P16278,Q13510,Q9NR77,Q15041,Q8WVQ1,Q969X5,P51798,Q7LGA3,Q9Y4P3,O95831,P08236,Q9Y619,P22413,Q7RTS9 20 +Bowing of the legs 0.3110632207583521 0.7459091106381349 0.4557223213056809 1.0 0.6547454299284329 59 O75718,Q9NR77,Q9NX62,P16435,Q32P28,Q9Y619,Q8WVQ1,Q7LGA3,Q96HY6,Q9Y4P3,P22413,P16278,Q7RTS9 13 +Redundant skin 0.3603703555402264 0.7457012880869898 0.4558478809055191 1.0 0.6547454299284329 27 Q9NX14,P38435,Q8NCH0,P48651,Q9Y4P3,Q9Y487 6 +Episodic tachypnea 0.4696842419248651 0.7434312048958472 0.4572206577508546 1.0 0.6553027150164557 9 Q8WXW3,Q10713,P22695 3 +Abnormal visual field test 0.5070257369408917 0.7420877888949473 0.4580341477899177 1.0 0.6556616657668828 6 P00846 1 +Broad phalanx of the toes 0.4688638461943223 0.7391324008988021 0.4598266038330323 1.0 0.6574111000974148 9 Q7LGA3,Q71SY5 2 +Aplasia hypoplasia involving the pelvis 0.4046561814323874 0.7359169556318603 0.4617812378458228 1.0 0.658273831557392 16 O95202,Q96HY6,O95831 3 +Retinal arteriolar tortuosity 0.4270747520450196 0.7359084412948114 0.4617864197694903 1.0 0.658273831557392 13 P00846,Q9Y4P3,O00192,P54198 4 +Protuberant abdomen 0.4937331662469816 0.7353602876392704 0.4621201007283537 1.0 0.658273831557392 7 P04062 1 +Abnormal respiratory system morphology 0.2716529272447437 0.7335929446995612 0.4631968621929161 1.0 0.6594053428397659 320 P00813,Q14108,Q15125,P01889,P15586,Q68CQ7,Q96HY6,Q13510,P35637,P16278,P31749,O75718,O95721,P16435,P09601,Q14739,Q96DF8,P07602,Q8N5M9,Q8IZA0,Q9NZ08,P14174,P54802,Q9Y487,Q14C86,Q92804,P04062,Q8N3R9,Q8NCH0,Q86YV9,Q7LGA3,Q9Y4P3,O75844,Q71SY5,Q9NSD9,P08236,Q8NFH4,P33991,O60220,Q15392,Q15165,P98175,O15460,Q9NZJ7,O95202,Q13501,P04066,Q9UHX1,P10253,Q8N1F7,Q01844,Q7RTS9,P06280 53 +Apraxia 0.2985690569033825 0.7322842557662427 0.4639950869587679 1.0 0.6603388680274797 67 Q9Y619,P04062,Q6DKK2,P05067,O60220,Q7LGA3,Q10713,O14773,P35637 9 +Abnormal renal vascular morphology 0.441220017767238 0.7283939102174816 0.4663724900379082 1.0 0.6617005965874434 4 P42224,O60333,P21912 3 +Femoral bowing 0.438250477963774 0.7248505967086042 0.4685436916652787 1.0 0.6635579917230596 11 P22413,Q32P28,Q7RTS9 3 +Single transverse palmar crease 0.3285146376580751 0.7246304264575919 0.4686787876274938 1.0 0.6635579917230596 47 Q9Y5Y5,O95202,Q9UHX1,Q71SY5,P40855,P98175 6 +Progressive muscle weakness 0.4174612193743645 0.7203204955688514 0.4713276883980495 1.0 0.6660935596353502 14 Q9Y5Y5,P40855 2 +Cerebral palsy 0.4310369663042316 0.7196099340836151 0.4717651938484235 1.0 0.6665096369262835 12 O75874,P48735,P98175 3 +Aplasia hypoplasia involving bones of the lower limbs 0.2776957355463554 0.7184312409390782 0.4724914297648945 1.0 0.6673332564720675 98 P00813,P13073,Q9NX62,Q9Y619,O95202,Q8WVQ1,Q8N3R9,Q9UHX1,Q7LGA3,Q96HY6,O95831,Q13510,Q96A33,Q7RTS9 14 +Retinal detachment 0.3933632805922897 0.7148455040363423 0.4747045139751948 1.0 0.6692414122567971 17 P31749,O43505,Q8NCH0,Q9H9S5 4 +Abnormal femoral head morphology 0.3656630016699529 0.7133629224399928 0.475621210393542 1.0 0.670330891985815 21 Q7LGA3,P16278,O95831,Q7RTS9 4 +Posteriorly rotated ears 0.2794101725414671 0.7105284755966956 0.4773764790823598 1.0 0.6723978347643278 123 P42892,Q9H9S5,P40855,P16435,Q8WVQ1,O43505,Q4J6C6,Q9Y5Y5,Q08J23,P04062,Q8NCH0,Q7LGA3,Q9Y4P3,Q15392,P98175,Q9Y619,O95202,Q9UHX1,Q9HC07,Q10713,O75381 21 +Abnormal elasticity of skin 0.3055557626816582 0.7091441398739414 0.4782350338705885 1.0 0.6731370349586718 61 Q9NWM8,P04062,Q8NCH0,Q9UHX1,O75844,Q9Y487 6 +Abnormality of adrenal physiology 0.3371304301825067 0.7078199247280521 0.4790570914463508 1.0 0.6733036830834372 39 Q9Y5Y5,P31749,O95470,Q13423,P40855,P33991,O75381 7 +Small earlobe 0.4628693066468285 0.7078170310795503 0.4790588886345137 1.0 0.6733036830834372 9 O00192,P54198,P10586,P98175 4 +Low set posteriorly rotated ears 0.2936524124427599 0.7073958315388273 0.47932052664334 1.0 0.6733036830834372 79 Q9Y5Y5,Q08J23,P16435,P04062,O95202,Q8WVQ1,Q8NCH0,Q10713,Q9Y4P3,Q4J6C6,P40855,Q15392,O75381,P98175 14 +Abnormality of lower limb joint 0.2771251222296357 0.70652954468012 0.4798588861741555 1.0 0.6734506453146177 186 Q05086,Q9NX62,Q96PU5,Q15125,Q9H9S5,Q96HY6,Q86XL3,Q13510,P16278,P31749,O75718,Q9NR77,P16435,Q15041,Q8WVQ1,Q969X5,P07602,Q9Y487,O75298,Q7LGA3,Q9Y4P3,O95831,O75844,P08236,O60220,Q96A33,Q9Y619,Q9NZJ7,O95202,Q9UHX1,P22413,Q7RTS9 32 +Cough 0.3605573912644274 0.703566371302267 0.4817028600040571 1.0 0.6754280318780548 24 Q9NR77,P04062,P01889,O15269,Q9NSD9 5 +Abnormal reflex 0.2633225889259327 0.6963246783283602 0.4862255216451154 1.0 0.6791916948766249 361 P07196,Q05086,P05023,P61978,Q96CU9,P01889,P20674,Q6DKK2,O15269,Q9H9S5,P00846,P40855,Q86XL3,O75306,Q5XKP0,P17900,Q13510,P35637,Q99720,O95721,Q9NR77,Q9BQT8,Q15041,Q14739,Q9GZY8,Q969X5,P07602,O43505,P50402,Q9NZ08,O75208,P54802,Q9Y5Y5,O60313,P13073,Q08J23,Q15067,P04062,O75298,Q8NI60,Q9Y4P3,Q3ZCQ8,O95831,Q16625,Q71SY5,O75503,O14773,O43464,O60220,O14949,Q8N2K0,Q96BR5,Q15555,Q9Y619,Q9NZJ7,Q9H0B6,O75489,P03886,Q96N66,Q13501,Q9H936,P10253,O43681,Q10713,O43292,Q9H6K4,Q05639,O14979,Q96IX5,O75381,Q7RTS9 71 +Specific learning disability 0.2867447004680338 0.6931890005466351 0.4881909500739185 1.0 0.6797728158896891 72 P22626,Q9Y619,Q13501,Q96DF8,Q96EK5,Q9BPX6,P03886,O75845,P53701,Q9H9S5,O43505,Q10713,Q9H6K4,Q9NSD9,P35637,P00403 16 +Neck muscle weakness 0.3900079063033577 0.6920005840988278 0.4889369621794666 1.0 0.6797728158896891 17 P46976,Q9NZJ7,P07602,Q86U42,P35637,Q99720 6 +Abnormality of the shoulder girdle musculature 0.3342507921572625 0.6918466416580116 0.4890336423457166 1.0 0.6797728158896891 36 P07196,O60313,P46976,P12235,O14979,Q8TD16,Q9NZJ7,Q13501,Q9H9S5,P07602,P50402,Q9Y487 12 +Supraventricular tachycardia 0.4845880260818036 0.6913684320957488 0.4893340370230223 1.0 0.6799874535958348 7 P35609,Q99996,Q8NFF5,Q99959,Q14BN4,P02545 6 +Abnormal aortic valve morphology 0.3331941309158404 0.6884221342719637 0.4911869891548162 1.0 0.6813418413024303 41 P04062,P61978,P01889,Q9UHX1,Q9Y4P3,O75844,P06280 7 +Hemorrhage of the eye 0.4457753854047793 0.68828478306572 0.4912734623600334 1.0 0.6813418413024303 10 Q9Y487 1 +Progressive spastic paraplegia 0.3542663262237678 0.6789316742388027 0.4971811552631275 1.0 0.687405705317794 26 O75298,O75489,Q9H0B6,Q96CU9,P00846,Q8IY17,O75306 7 +Abnormal lymphocyte morphology 0.3374783054050967 0.6770578396009563 0.4983692572476483 1.0 0.6886395729040481 32 P00813,O95470,P33991 3 +Sudden loss of visual acuity 0.3952215494293867 0.676310762049253 0.4988433612967804 1.0 0.6890902659906296 3 O00170 1 +Abnormal heart valve morphology 0.2950844497117819 0.674704235335474 0.4998636931559286 1.0 0.6900904216716999 83 Q96PU5,P61978,P55795,P01889,Q9Y2B2,O00571,P16278,Q9NX14,Q6NUK1,P51798,Q15233,O00192,P04062,Q8NCH0,Q9Y4P3,P54198,O75844,Q9BUB7,P08236,O95202,Q9UHX1,P53701,P22413,O60826,P06280 25 +Convex nasal ridge 0.3611667974343091 0.6719033777403458 0.5016452099179927 1.0 0.6912895706581794 20 O75844 1 +Chronic pulmonary obstruction 0.4559263824169486 0.6717765098278934 0.5017259851737297 1.0 0.6912895706581794 9 P09601,O00192,P54198,P06280 4 +Abnormal circulating metabolite concentration 0.2631566884127608 0.6708198911444445 0.5023352742638965 1.0 0.6918621252280395 357 P05023,Q15125,P20674,Q9P0J1,P00846,Q9H9P8,Q9BT22,O43676,Q70HW3,P22830,P07602,P51798,P49257,Q96EY8,P14174,Q9Y487,Q9Y5Y5,O95298,P50416,Q8N511,Q9NPL8,Q96JX3,P42167,O95831,O75844,P28288,O95470,Q9Y619,P03886,P22695,Q9HC07,Q13423,Q9BWD1,Q9NWM8,P05067,P48735,Q15800,Q86Y39,O14979,P06280,P07196,P09493,Q96CU9,Q9BPX6,Q9H9S5,P40855,Q5XKP0,Q96DF8,O43505,P61916,P50402,O75208,Q14C86,P53985,P31751,Q9NSD9,Q8NFH4,Q15392,Q9NZJ7,O75845,P10253,P22413,Q8N1F7,Q9NVI7,Q96BR5,O75381,O75306,P22626,O75880,P36551,Q14739,Q969X5,Q4J6C6,P0DP25,Q08J23,Q9Y4P3,P61457,Q9BUB7,Q8N5M1,P31483,O75489,Q13501 82 +Hammertoe 0.3598926672513679 0.6691527504007452 0.5033980432764542 1.0 0.6924036234545768 21 P07196,Q9NR77,Q96BR5 3 +Limb undergrowth 0.3087260394640764 0.6684096274754394 0.5038721516685634 1.0 0.6927498472468029 55 O75718,Q15125,Q9UHX1,Q96HY6,O75874,P48735,Q15392,Q7RTS9,P98175 9 +Abnormal venous morphology 0.3460915815493904 0.667586404076914 0.5043976387282016 1.0 0.6927769947023728 29 P31749,O00192,P04062,Q6NUK1,P48651,P54198,Q71SY5,P98175,Q9Y487 9 +Hyperacusis 0.4676138412757842 0.667310572369524 0.5045737746231151 1.0 0.6927769947023728 8 P17900 1 +Inappropriate crying 0.479546738252506 0.6672899778004673 0.5045869268517447 1.0 0.6927769947023728 7 P07602 1 +Hyperventilation 0.4795307574639715 0.6672138595685715 0.5046355395073316 1.0 0.6927769947023728 7 P00846 1 +Abnormality of the pharynx 0.3174140590260118 0.662675415227427 0.5075384585012537 1.0 0.6953568031530948 50 P00813,Q7RTS9,O15460,P01889,P16278,P15586,Q86YV9,P08236,Q13510,P54802 10 +Myopathy 0.2744147824569504 0.6618517177998754 0.508066257421667 1.0 0.6956168066778331 99 P07196,P09493,Q9H9S5,P00846,O43676,O75306,P00403,Q9NWM8,P31749,P22626,Q969X5,Q86U42,P21912,P50402,Q86Y39,O60313,O75340,Q13126,Q8NCH0,P42167,P06753,Q9Y4P3,O76024,Q9Y6B6,P13473,P46976,P12235,O14979,Q7Z406,P31483,P09651,Q9BTV4,Q13501,P03886,Q03252,O75648,P23786 37 +Myotonia 0.4783611831624527 0.661646773235893 0.5081976240544197 1.0 0.6956168066778331 7 P50402,Q13642,Q9BTV4 3 +Kyphoscoliosis 0.3040363517624876 0.6612998489467601 0.5084200383286697 1.0 0.6956168066778331 59 Q9NWM8,Q9NR77,Q8NCH0,Q9HC07,O75844,Q9Y487 6 +Bilateral tonic clonic seizure 0.292887855552357 0.658351312807465 0.5103124127865146 1.0 0.6970777767623417 86 P27544,P04062,Q9NZJ7,Q14739,P03886,Q13501,Q9H936,Q01105,P07602,P00846,O43292,Q05639,Q13510,Q9NQZ5,P00403 15 +Irritability 0.2913900676339345 0.6542703817815824 0.5129376242313242 1.0 0.6990238307985688 81 P50897,Q15067,Q9NZJ7,P01889,Q8NFH4,P07602,P00846,P22413,O95831,Q8N1F7,P61457,Q13510,Q9NZ08,Q14C86 14 +Cutaneous photosensitivity 0.3541161733321565 0.6520486525476401 0.5143697869305708 1.0 0.7003608499042966 24 Q14108 1 +Abnormality of the calf musculature 0.3917923768976206 0.6512798379706916 0.5148658610287407 1.0 0.7005296843980509 16 Q9NR77 1 +Prominent nasal bridge 0.3071606678694016 0.6502653128765348 0.5155208589386304 1.0 0.7005296843980509 55 O43924,O95721,P13073,P78318,Q08J23,O00192,Q15125,P42892,Q9Y2B2,Q5JRA6,Q8WXW3,Q8N5M1,Q10713,P54198,P20700,Q15233,Q96EK5 17 +Broad foot 0.4386783634540101 0.6499744749648476 0.5157087095101724 1.0 0.7005296843980509 10 O95831 1 +Middle age onset 0.4385564692941864 0.6493192241481047 0.5161320624528973 1.0 0.7005296843980509 10 P07602,Q9NZJ7 2 +Female sexual dysfunction 0.4635828470217867 0.6473770633391905 0.5173879368626029 1.0 0.7012235938846657 8 O43464,O75298 2 +Bradykinesia 0.3531913875750635 0.644677831268052 0.5191359854163671 1.0 0.7019596957167678 24 P04062,Q96IX5,Q6DKK2,O75569,O43464,Q8TAB3 6 +Hypotension 0.3483114765002137 0.6444371529884831 0.5192919989203868 1.0 0.7019596957167678 27 Q9NZJ7,P04062,P07686,P07602,O43681,Q13423,O43772,P20700 8 +Cerebral cortical atrophy 0.2749554436960456 0.6444070239346333 0.5193115310090128 1.0 0.7019596957167678 107 Q05086,Q8TD16,O96008,Q9Y2B2,Q9H9S5,P00846,P51572,P00403,Q96AA3,P05067,O43924,P04062,P62258,Q8N3R9,Q7LGA3,Q9Y4P3,Q16625,O76024,O75503,Q9BUB7,Q9Y619,Q13501,P03886,O75648,Q9UNW9 25 +Progressive inability to walk 0.3571386247574867 0.6416215411663992 0.5211189429915546 1.0 0.703790094651975 20 P00846,Q96D71 2 +Restlessness 0.3280508537518429 0.6374532292521574 0.5238296658129455 1.0 0.7064269204854372 41 Q92804,P04062,P42892,P05067,Q68CQ7,P35637 6 +Failure to thrive 0.268496617053152 0.6370478130704347 0.524093700023081 1.0 0.7064544256509832 311 P00813,Q15125,Q96CU9,P55795,P42892,P00846,O43676,P40855,O75306,Q5XKP0,Q13510,P51572,P00403,P31749,O95721,O75880,Q9BQT8,Q14739,P07602,Q4J6C6,Q15800,Q8N5M9,Q86Y39,Q9Y487,Q9Y5Y5,P51571,P13073,Q15067,P04062,Q96JX3,Q9Y4P3,Q3ZCQ8,Q16625,O75844,Q9NSD9,Q9BUB7,Q8N5M1,P33991,Q15392,P98175,P46977,Q9Y619,Q9NZJ7,O75489,O95202,P03886,Q9H936,P04066,O75845,P10253,Q9HC07,P22413,Q13423,Q05639,O75381,Q7RTS9 56 +Hypoplastic heart 0.3536549274933489 0.6369561740497856 0.5241533909510085 1.0 0.7064544256509832 2 O60826 1 +Insulin resistance 0.3893868497411569 0.6355810878895028 0.5250494993487218 1.0 0.7071912130921106 16 Q9Y6M1,O76024,Q03252,P31751,P22413,O75844,P18031 7 +Neoplasm of the small intestine 0.4838891080608731 0.6354933531591512 0.5251067004242955 1.0 0.7071912130921106 6 P25054,P21912 2 +Gastroparesis 0.4610947605344968 0.6351211832957132 0.5253493822809274 1.0 0.707247810018659 8 P61978,O43464,Q9BUB7 3 +Abnormality of the curvature of the vertebral column 0.2660544506364761 0.6329843089432253 0.5267438897296151 1.0 0.7079194355709184 331 P07196,P51648,Q05086,Q14108,Q96PU5,P61978,Q15125,Q96CU9,P55795,P01889,Q01105,P48651,Q9H9S5,Q96HY6,Q9BT22,O75874,Q13510,P35637,P16278,Q99720,Q9NWM8,P31749,O75718,P22626,Q9NR77,P16435,Q9BQT8,Q14739,Q8WVQ1,Q969X5,P48735,P50402,Q9Y487,Q9UG56,P51571,Q08J23,Q32P28,P04062,Q8N3R9,Q8NCH0,Q8WXW3,Q7LGA3,Q9Y4P3,O95831,O75844,Q71SY5,Q9NSD9,P08236,Q96A33,P98175,O75489,Q9H0B6,O95202,P04066,Q9UHX1,Q9HC07,Q10713,P22413,Q9NVI7,Q05639,Q7RTS9 61 +Elevated circulating growth hormone concentration 0.3872113676731754 0.6327267073857746 0.5269121260464464 1.0 0.7079194355709184 3 O00170,P10644 2 +Pituitary prolactin cell adenoma 0.3872113676731754 0.6327267073857746 0.5269121260464464 1.0 0.7079194355709184 3 O00170,P10644 2 +Adrenocorticotropic hormone deficiency 0.3872113676731739 0.6327267073857658 0.5269121260464522 1.0 0.7079194355709184 3 P04637,O00170 2 +Tube feeding 0.2839549192309223 0.6303428570485712 0.5284702887665449 1.0 0.7092078317361689 74 Q9NZJ7,P61978,Q9GZY8,Q96N66,Q01105,Q9UHX1,P07602,Q2M389,Q71SY5,Q05639,P35637,Q99720 12 +Head titubation 0.4716892402102791 0.6300351630931303 0.5286715784715075 1.0 0.7092078317361689 7 P35637,Q99720 2 +Cerebellar vermis atrophy 0.4093768429645841 0.6298623795426105 0.5287846285143225 1.0 0.7092078317361689 13 Q9Y5Y5 1 +Abnormal periventricular white matter morphology 0.326971623182828 0.6267840089157106 0.5308008270592603 1.0 0.7105569166192764 41 O60313,P51571,Q9NZJ7,O95202,Q9UHX1,Q9H9S5,P07602,O75503,P17900 9 +Lymphopenia 0.3509315341831825 0.6266963097686142 0.530858323279322 1.0 0.7105569166192764 24 P00813 1 +Bilateral single transverse palmar creases 0.3952024725635457 0.6259050773987417 0.5313772040064808 1.0 0.7110471175702924 15 Q9Y5Y5,P40855 2 +Abnormal urine cytology 0.3286700958302507 0.6255436513795104 0.5316143084004832 1.0 0.7111206163036431 39 Q02978,Q14108,Q13263,P04062,P09601,O15460,P01889,Q8N1F7,P49257,P06280 10 +Abnormal atrioventricular conduction 0.3801517709118269 0.625355953732496 0.5317374638440509 1.0 0.7111206163036431 17 P50402,P06280,Q9BTV4,P21912,O43772,Q13642,P0DP25 7 +Subcapsular cataract 0.4706118129609417 0.6249547572152511 0.5320007523493435 1.0 0.7112685144785426 7 Q8N2K0 1 +Hyperlipoproteinemia 0.4461279218868519 0.6213927968472229 0.5343412102734706 1.0 0.7124228435681172 9 Q8N511 1 +Increased ldl cholesterol concentration 0.4461279218868519 0.6213927968472229 0.5343412102734706 1.0 0.7124228435681172 9 Q8N511 1 +Sclerocornea 0.4331674054052576 0.6204497652480622 0.5349617172184988 1.0 0.7124228435681172 10 P53701,O95202,Q6NUK1,Q9NX14 4 +Pelvic kidney 0.4458513645407461 0.6199797089171678 0.5352711460200268 1.0 0.7124228435681172 9 Q9UHX1 1 +Abnormality of the abdominal organs 0.2605496592068109 0.6199187476894339 0.535311282200174 1.0 0.7124228435681172 360 P10619,P00813,Q14108,Q96CU9,P01889,P15586,P00846,Q96HY6,O43676,P40855,O75306,Q5XKP0,Q13510,P16278,P00403,O15118,P31749,P22626,O75880,P36551,P09601,P22830,Q14739,P07602,P61916,Q9BW92,Q86Y39,Q9NZ08,P14174,P54802,Q14C86,Q9Y5Y5,Q8N511,P53985,Q15067,P04062,Q8NCH0,P31751,Q9Y4P3,Q16625,Q71SY5,Q9NSD9,Q9BUB7,P08236,Q8NFH4,P33991,Q15392,Q96A33,Q8N5M1,Q9Y619,Q9NZJ7,O75489,O95202,P03886,P00374,P04066,O75845,Q9UHX1,Q9HC07,Q10713,P10253,Q01844,P22413,Q8N1F7,Q9NVI7,O75381 66 +Abnormal sacrum morphology 0.3262952637101194 0.6159862961398824 0.5379035643450325 1.0 0.7154818630601323 36 Q08J23,P61978,Q15125,Q14739,O95202,P01889,P04066,Q9Y4P3,P22413 9 +Recurrent hand flapping 0.4489758900431934 0.6159659072879601 0.5379170211328002 1.0 0.7154818630601323 5 Q9UNW9,P55795 2 +Abnormal duodenum morphology 0.3934665532293677 0.6149818000409668 0.5385667398146008 1.0 0.7161415569672882 15 Q8NCH0 1 +Dolichocephaly 0.3253280077085791 0.6129022260645507 0.539940991275885 1.0 0.7173545742621427 37 Q9Y5Y5,P31749,O95721,P61978,O95202,Q969X5,P40855,O75381,Q7RTS9 9 +Abnormal enzyme coenzyme activity 0.272303400753964 0.6124566340581482 0.540235681391793 1.0 0.7175414325414805 194 P10619,P00813,P01889,Q9H9S5,P00846,P40855,Q5XKP0,Q13510,P16278,O15118,P22626,O75880,P07602,O43505,P61916,Q9Y5Y5,Q8N511,Q15067,P04062,Q9NSD9,Q96A33,P48637,Q9Y619,Q9NZJ7,P03886,P22695,O75845,P10253,Q9HC07,Q10713,P22413 31 +Optic nerve hypoplasia 0.352176037956158 0.6104461243077813 0.5415663219438949 1.0 0.7188278366368482 21 P07196,Q9H9S5,Q9UHX1,Q9NVI7 4 +Cardiomegaly 0.3270957822804565 0.6102938409060631 0.541667176169029 1.0 0.7188278366368482 39 O95298,P50416,P04062,Q14739,P20674,P07686,P04066,P10253,Q9Y4P3,P22413,P13473,P54802 12 +Multifocal epileptiform discharges 0.3299933876268877 0.6089224389720064 0.5425758501391451 1.0 0.7196421699304322 32 Q08J23,Q9UBX3,Q96N66,Q9H936,Q2M389,Q71SY5,O75503 7 +Genu valgum 0.3259311209419948 0.6086683366039229 0.5427442986186364 1.0 0.7196421699304322 38 Q9NR77,Q9NX62,Q9Y619,Q7LGA3,Q9Y4P3,P22413,P16278,Q7RTS9 8 +Abnormal platelet morphology 0.4670373932520185 0.6081517180983184 0.5430868535271229 1.0 0.7197706695003199 7 O75845 1 +Abnormal renal physiology 0.2715395460867892 0.6074466467070284 0.5435545398276533 1.0 0.720101549066328 165 P00813,Q13277,P05023,Q14108,Q96CU9,P01889,Q9BT22,Q8IY17,O43676,P40855,O43772,O75306,P00403,Q7Z4L5,O95721,Q8N183,Q9NX14,P09601,P36551,P49257,P51809,Q86Y39,Q9NZ08,Q14C86,P50416,Q02978,Q9NPL8,P04062,P62258,Q8NCH0,Q9Y4P3,Q16625,O76024,Q8NFH4,Q9BRT2,O95470,Q13263,O15460,O75489,P03886,Q03252,Q10713,P22413,Q8N1F7,P06280 45 +Limb girdle muscle atrophy 0.4048960609521232 0.6033611232429492 0.5462684789708985 1.0 0.7218914721528857 13 P50402,P09651,Q9BTV4,Q9H9S5,P06753,O14979 6 +Polygenic inheritance 0.4766023332146718 0.6025054803163213 0.5468377163263582 1.0 0.7222276408098349 6 P22413 1 +Gangrene 0.4158331837328078 0.5984603198369013 0.549532827830634 1.0 0.7253397313786039 11 P22413,Q9NZ08,P01889 3 +Flat acetabular roof 0.4756066554030021 0.5980231226953623 0.5498245046136989 1.0 0.725519133850031 6 Q8WVQ1,Q7RTS9 2 +Abnormality of skeletal muscle fiber size 0.3598687723159463 0.5976091716864801 0.5501007429970239 1.0 0.7256780687850857 19 O60313,P22626,Q7Z406,P09651,Q13501,Q9BPX6,P06753,O95831,Q13642 9 +Limb girdle muscle weakness 0.3440557745715411 0.5950728329740854 0.5517947873333129 1.0 0.7272948838139704 26 O60313,P46976,P12235,O75340,Q8TD16,Q9NZJ7,Q13126,Q9H9S5,P07602,O14979 10 +Abnormal metacarpal morphology 0.3282923952783914 0.5935065263650571 0.5528422165942044 1.0 0.7278516237693058 32 Q9NX62,P16435,Q32P28,Q14739,Q8WVQ1,P16278,Q7RTS9 7 +Abdominal aortic aneurysm 0.4145243714635546 0.5929654157719296 0.5532042975647102 1.0 0.7280353819879217 4 P01889 1 +Cirrhosis 0.3232337472617886 0.5928308096899991 0.5532943864828774 1.0 0.7280353819879217 37 Q14108,P04062,P22830,Q10713,Q9NSD9 5 +Hamartomatous polyposis 0.4144403292807205 0.5925474542029612 0.5534840536319559 1.0 0.7280792775536997 4 P31749,P21912 2 +Focal t2 hyperintense basal ganglia lesion 0.3496017153963036 0.5909846362195441 0.5545307152067602 1.0 0.7290995287205023 21 O75306,P00846,Q96CU9,P03886 4 +Renal dysplasia 0.3895879198852929 0.5906682666914241 0.5547427142199584 1.0 0.7291172581367286 15 Q9H936,Q9H9S5,O43505,Q8N201,O75306 5 +Oculomotor apraxia 0.3412098901307274 0.5853125319494032 0.5583375899091454 1.0 0.73213986690439 27 O43924,P04062,Q13501,O96008,Q9Y2B2,P05067,Q8WXW3,Q10713,O43292,O14773 10 +Arthrogryposis multiplex congenita 0.3235479370413716 0.5849134517754534 0.5586059131483818 1.0 0.73213986690439 35 Q8TD16,P04062,Q15058,Q969X5,Q8NCH0,O75844,Q15392 7 +Urinary incontinence 0.3226400300160468 0.5840682317578734 0.5591744071858784 1.0 0.7324618640809397 41 P07196,P31749,O75298,Q9NZJ7,Q13501,P07602,Q3ZCQ8,P35637,Q99720 9 +Dermal atrophy 0.336304568939058 0.5832127526297372 0.5597500873356636 1.0 0.7328037961803038 29 Q9NWM8,Q8NCH0,P53701,P22413,O75844,Q15392 6 +Erythrocyte inclusion bodies 0.4124962984897686 0.5828962735008884 0.5599631294056333 1.0 0.7328767228916662 4 P08865,Q9Y606,O14936 3 +Hydrocele testis 0.4500756388882049 0.5813246119773451 0.5610216959227563 1.0 0.7334634119871878 8 Q9UBX3,Q9NVI7 2 +Heat intolerance 0.4406860130918947 0.5767934794273246 0.5640789749353801 1.0 0.7359887577728292 5 P61978 1 +Hand muscle weakness 0.4060078533676865 0.5749484407923875 0.5653261675146386 1.0 0.7372030482315751 12 P07196,Q13501,P31483,Q9NR77 4 +Anophthalmia 0.4057397105009849 0.5734247482043161 0.5663571375932679 1.0 0.7381341765275439 12 P53701,Q9H9S5,O43505,Q9NX14 4 +Abnormality of hair texture 0.2983952865721022 0.5696472619021883 0.568916966270919 1.0 0.7406414837590668 57 Q15125,P55795,P15586,O75844,Q9NVI7,Q96A33,P54802,Q9Y487 8 +Proximal muscle weakness in upper limbs 0.3986500527378785 0.5667017134375909 0.5709168565407077 1.0 0.7424150524194909 13 P07196,P50402 2 +Abnormal macroscopic urine appearance 0.3452420876413603 0.5646000942584481 0.5723458011481184 1.0 0.7434233191999426 22 Q8NFH4,Q8N1F7,Q14C86 3 +Elevated hepatic transaminase 0.2685406043137568 0.5636760690228799 0.5729746067299364 1.0 0.7436377035798395 100 O60762,P01889,P20674,P40855,O43772,Q5XKP0,Q13510,Q2TAA5,P56192,O75880,Q14739,Q9Y5Y5,P50416,Q8N511,Q15067,Q16625,Q9NSD9,P28288,P12235,P09622,Q9Y619,P22695,O75845,O75648,P10253,Q9HC07,Q10713,P23786 28 +Scarring 0.3279189496998413 0.5631108111684413 0.5733594301426037 1.0 0.7437443510275852 31 Q9NWM8,Q15555,Q92542,P53634,P36551,Q15125,Q8NCH0 7 +Bladder diverticulum 0.4462507976560186 0.5628518208302418 0.5735357898005766 1.0 0.7437443510275852 8 Q9NWM8 1 +Diminished movement 0.344818860165494 0.5613741791864801 0.5745424825029017 1.0 0.7445582720955112 22 P04062 1 +Prolonged partial thromboplastin time 0.4669690996905166 0.5594125674903 0.5758801863540501 1.0 0.7457464298129457 6 P38435,P28288,P49257 3 +Distal lower limb muscle weakness 0.3538069331458086 0.5543219565540624 0.579358526389917 1.0 0.7490013921521603 19 P00846,Q9NR77 2 +Generalized hypotonia 0.2564178970381136 0.5514231138982573 0.5813436594749974 1.0 0.7503183058560648 367 Q15907,P50897,Q05086,Q9BWD1,Q15125,P61978,Q96CU9,Q01105,P48651,Q9H9S5,Q9P0J1,Q9BT22,O43676,P40855,Q5XKP0,P17900,O15118,Q70HW3,Q9NR77,O75880,Q9UBX3,Q8WVQ1,P11117,P07602,P61916,Q2M389,Q4J6C6,Q86Y39,O75208,Q9Y487,Q9Y5Y5,P51571,Q8N511,P13073,Q08J23,Q8NI60,Q8NCH0,Q96JX3,Q6P4A7,O95831,Q96D71,Q3ZCQ8,Q71SY5,Q9NSD9,P61457,O43464,Q9BUB7,O14949,Q96A33,Q8N5M1,P98175,P46977,Q96EK5,O95470,Q15555,Q9Y619,Q9NZJ7,O75489,O95202,Q96N66,P00374,O75845,Q9BW92,Q9UHX1,Q9HC07,Q10713,O43292,P06865,P10253,Q9NVI7,Q05639,O43681,Q9UNW9,O75381 74 +Short palpebral fissure 0.3321845514078814 0.547967161668945 0.5837144511895489 1.0 0.7523358919869725 29 Q9Y619,O75844,P98175 3 +Dry skin 0.3358547249907261 0.5410581334860379 0.588467514060085 1.0 0.7578329224472977 27 P00813,P51648 2 +Ependymoma 0.4522545084721007 0.5395811829341643 0.5894858964138554 1.0 0.7581877888417148 7 P25054,O75874 2 +Dysuria 0.4407582385088758 0.5365237365868489 0.5915966355474329 1.0 0.759343380650301 8 P01889,O00170,O76024 3 +Occipital meningocele 0.4512900163439453 0.5351637814426125 0.5925366087071744 1.0 0.7603403645614375 7 Q10713,O00192,P54198 3 +Congenital malformation of the right heart 0.4400180820688022 0.5329946854855987 0.5940372591827607 1.0 0.7617293557049633 8 P01889,P40855 2 +Prolonged qtc interval 0.3683211805871075 0.5323768781627948 0.5944649960448611 1.0 0.7617655987832086 3 P0DP25 1 +Encephalopathy 0.268020132041963 0.5307935763034292 0.5955618319625047 1.0 0.7625417848491882 107 O60762,Q96CU9,O43676,O43772,O75306,P00403,Q8N183,P07602,Q86Y39,O75208,P50416,Q15067,Q9NPL8,P04062,Q96JX3,Q3ZCQ8,Q9BUB7,P09622,Q9Y619,Q9NZJ7,O75489,P03886,Q9H936,Q9H3H1,Q9NVI7,Q05639 26 +Toxemia of pregnancy 0.46014960282037 0.5293021189679125 0.5965958859011891 1.0 0.7631392806768751 6 Q14739 1 +Abnormality of lower limb epiphysis morphology 0.3580556135010973 0.5284629108867538 0.5971780829460909 1.0 0.7633522256758758 18 Q7LGA3,O95831,Q7RTS9 3 +Bone spicule pigmentation of the retina 0.4389589990740693 0.5279530360913913 0.5975319325602828 1.0 0.7635949909096837 8 Q9UG56,Q96S66 2 +Acetabular dysplasia 0.4388594506753974 0.5274796374374006 0.5978605532702161 1.0 0.7635959575356915 8 P16278,Q969X5 2 +Hepatosplenomegaly 0.3168155731944839 0.5263685187312365 0.5986321844954143 1.0 0.7638653147929619 36 P10619,P04062,O75845,P16278,Q96HY6,Q13510 6 +Diabetes insipidus 0.391492495348462 0.5251432786333043 0.5994835921736184 1.0 0.7646206386486074 13 P31749,O15460,P01889,Q8N5K1,O76024,P06280 6 +Fasting hypoglycemia 0.3665802593731911 0.5233279270374 0.6007460698877607 1.0 0.7660211315459046 3 O43772 1 +Pierre robin sequence 0.4377212500068627 0.5220730226034035 0.6016194888982898 1.0 0.7663481157356145 8 P98175 1 +Overlapping fingers 0.4263199649125968 0.5216430508453795 0.6019188828480859 1.0 0.7663481157356145 9 Q15125 1 +Limited wrist movement 0.4583975463894155 0.5216233468160075 0.6019326045848661 1.0 0.7663481157356145 6 O75844 1 +Premature loss of teeth 0.3907903270119198 0.5210945095797366 0.602300935505693 1.0 0.7663481157356145 13 P51798,P53634,O75844 3 +Supraventricular arrhythmia 0.3490763738220225 0.5208328574954375 0.602483211641009 1.0 0.7663481157356145 19 P00846 1 +Congenital nystagmus 0.3408032530249937 0.5204642032390814 0.6027400714452604 1.0 0.7664655344777568 20 Q7LGA3,P00846 2 +Axonal degeneration regeneration 0.4280213270142131 0.5179996125514403 0.604458539657033 1.0 0.7677761567318455 5 Q8TB36,P02545,O60333,P51149 4 +Hyporeflexia of lower limbs 0.4255444121750121 0.5178042134772515 0.6045948782508392 1.0 0.7677761567318455 9 Q9NR77 1 +Optic disc coloboma 0.4278653557015081 0.5172842305985292 0.6049577605415717 1.0 0.7679958959489068 5 Q10713 1 +Lower limb muscle weakness 0.3138280966146459 0.5170837909693183 0.6050976681263391 1.0 0.7679958959489068 43 P07196,P31749,Q9NR77,O75298,P00846,Q13510 6 +Abnormal pulmonary thoracic imaging finding 0.3394341538111332 0.5104536359581232 0.6097336885825277 1.0 0.7721967159916842 20 Q13510,P01889,P04062 3 +Abnormal blood sodium concentration 0.4121122476971799 0.5098368001748378 0.6101658016995128 1.0 0.7725339234347189 10 Q13423 1 +Aplasia hypoplasia involving the metacarpal bones 0.3331319816329045 0.5065014310814329 0.6125046853063172 1.0 0.7742325167318387 26 Q32P28,Q9NX62,P16435,Q14739,Q7RTS9 5 +Increased intracranial pressure 0.3382760161322838 0.5062537820369072 0.6126785038853613 1.0 0.7742421245518212 21 P31749,P01889,Q9NZJ7,P07602 4 +Premature skin wrinkling 0.3388072550223954 0.5058784358110289 0.6129419914196648 1.0 0.7743650111290475 20 Q9Y487 1 +Atypical absence seizure 0.395264660283024 0.4989072525255756 0.6178447245304595 1.0 0.7792907465103927 4 Q05086 1 +Abnormality of mouth shape 0.2773584049514535 0.4965213918580613 0.6195265984865173 1.0 0.7812005673389815 69 P04062,P61978,Q15125,Q96DF8,O95202,O75845,Q10713,Q86XL3,Q05639,Q96A33 10 +Abnormal cortical bone morphology 0.3361459935632416 0.4957542600131986 0.6200677995931798 1.0 0.7812391252876211 22 P31749,Q15058,P48651,P51798,P22413,P40855,Q86XL3,Q9NSD9 8 +Abnormal midbrain morphology 0.4320042022005066 0.495090009905858 0.6205365853397917 1.0 0.7812391252876211 8 Q10713,P04062 2 +Aplasia hypoplasia of the earlobes 0.4091502848798721 0.4946012791850274 0.620881599064681 1.0 0.7812391252876211 10 O00192,P54198,P10586,P98175 4 +Abnormality of limb epiphysis morphology 0.3172590081666009 0.4943019855557572 0.6210929230783331 1.0 0.7812391252876211 32 P16435,O95202,Q7LGA3,O95831,Q7RTS9 5 +Tented upper lip vermilion 0.3350289145506036 0.4938073431852043 0.621442246656831 1.0 0.7812391252876211 23 Q15907,O60762,Q14696,Q9Y2B2,Q9Y263,Q4J6C6,Q02252,Q71SY5,Q10471,Q05639 10 +Onset 0.2467704468058609 0.4937263780150276 0.6214994335570618 1.0 0.7812391252876211 399 Q13277,P50897,Q96PU5,Q15125,P20674,Q9P0J1,Q9H9P8,O00571,Q13510,Q70HW3,Q9NR77,P78318,P22830,Q8IV08,P07602,P51798,Q96EY8,Q8TAB3,P54802,O95298,Q9Y6M1,Q9NPL8,P04062,Q8WWV3,O95831,Q9H0U3,O14773,Q14566,P28288,Q9UHX1,Q9H3H1,P06865,O60762,Q8TCJ2,Q8TD16,Q8IY17,Q96AA3,Q9NX14,Q6NUK1,P07686,Q5JRX3,Q9Y289,Q86U42,P18031,O43924,Q15067,P38435,Q66GS9,P08670,Q7LGA3,O76024,O60220,Q9BRT2,Q8N2K0,P12235,O00584,Q9BTV4,Q03252,O75648,Q5JRA6,Q9Y4W6,Q10713,O43292,Q9Y263,Q05639,O14979,P23786,P20700,P06280,P07196,Q96D09,Q96CU9,Q9H9S5,Q5XKP0,O15118,O43505,P61916,P50402,P31751,Q71SY5,Q9NSD9,Q8NFH4,P46977,Q9NZJ7,Q96N66,P22413,Q9NVI7,P55795,O75306,P16278,P31749,O95721,P36551,Q9GZY8,Q969X5,Q14574,Q4J6C6,P51571,Q9BUB7,Q8N5M1,Q9NQZ5,Q96EK5,P31483,Q9BW92 104 +Open mouth 0.3143192355356896 0.4932193138234621 0.6218576324935512 1.0 0.7812391252876211 33 P04062,P61978,Q96DF8,Q10713,Q86XL3 5 +Sudden death 0.3199218318674611 0.4926352610312826 0.6222703285402351 1.0 0.7814869750176369 31 P31749,P50416,O15460,O95677,Q9BTV4,P01889,Q9Y4P3,P22413,P50402,Q13642,P0DP25 11 +Abnormality of female external genitalia 0.3128010069802128 0.4878268192488694 0.625672513148114 1.0 0.7839989407737216 41 Q9Y5Y5,Q08J23,P16435,Q9NX14,Q9Y619,P53701,P51809,P40855,Q15392,O75381 10 +Poor motor coordination 0.3727989384000147 0.4871473719234604 0.6261538977359129 1.0 0.7841683151116867 15 Q10713,O75503 2 +Joint dislocation 0.2634590504365001 0.4870015672273509 0.6262572203124677 1.0 0.7841683151116867 99 P31749,P51571,Q9NX62,Q9Y619,Q15125,O95202,Q8WVQ1,Q969X5,Q8NCH0,Q9UHX1,Q9H9S5,O75844,Q96A33,Q9Y487 14 +Macroorchidism 0.449923444710508 0.4848373448750726 0.6277917297506073 1.0 0.7845620352000511 6 P38159 1 +Diffuse cerebral atrophy 0.3658181500964399 0.4846463643566361 0.6279272190598344 1.0 0.7845620352000511 16 P07602,P16278,Q10713,Q9NZJ7 4 +Type ii lissencephaly 0.4495057578821141 0.4830399772281705 0.6290673511176308 1.0 0.7853647069166241 6 Q9H9S5 1 +Anhidrosis 0.4493802807077638 0.4825003309259384 0.6294505633841385 1.0 0.7856325627661621 6 P04066 1 +Multifactorial inheritance 0.3778329771000498 0.4802071473412258 0.6310801051200932 1.0 0.7864085418337451 14 P22413,P10321,P01889,P42892 4 +Echolalia 0.406334016538859 0.4801999006479029 0.63108525748702 1.0 0.7864085418337451 10 P53701,Q13501,Q9UHX1 3 +Acidemia 0.3835728859044406 0.4797959167362203 0.6313725166170672 1.0 0.78655607980805 13 Q9H9P8 1 +Thoracolumbar kyphosis 0.4486512132831769 0.4793675514306554 0.6316771733481268 1.0 0.7866223051262162 6 P04062 1 +Abnormal circulating albumin concentration 0.3127405074004578 0.4789066193882794 0.6320050616757524 1.0 0.7867128747422916 33 O95470,Q9NSD9,Q5XKP0,Q8NFH4,Q14C86 5 +Azoospermia 0.388534206169209 0.4771407555172573 0.6332618948962541 1.0 0.7880667663443097 12 P04062 1 +Gonosomal inheritance 0.2742630444679155 0.4766676268555911 0.6335988188336588 1.0 0.7882754535596107 70 P51571,P06280,P78318,Q15125,Q96D09,P55795,O60220,P53701,O00571,O95831,Q9H0U3,P98175,P50402,P51572,P38159,Q8TAB3,P13473 17 +Sleep disturbance 0.2641013570021681 0.474446875498335 0.635181272706935 1.0 0.7894008453225463 157 P07196,P50897,P61978,Q01105,P15586,Q9H9S5,P31749,P36551,Q2M389,P54802,Q08J23,P04062,Q8N3R9,Q7LGA3,Q9Y4P3,O95831,Q71SY5,O75503,O43464,Q96A33,Q96N66,Q9H936,Q9UHX1,Q9NVI7,Q05639 25 +Attenuation of retinal blood vessels 0.437391586308424 0.4723811729640622 0.6366547402105733 1.0 0.7903885340887129 7 P38435,Q96S66 2 +Abnormality of coagulation 0.2856387081738771 0.4667644969372043 0.6406683793012773 1.0 0.7936790720173802 61 Q9Y5Y5,O60762,P51571,P09622,Q9Y619,P38435,Q96JX3,P28288,P48735,O75874,P40855,P49257,Q5XKP0,O75381,Q9Y487 15 +Abnormality of the peritoneum 0.3327682223833653 0.4656626349473426 0.6414570018457773 1.0 0.7944447526183542 21 Q8NFH4,Q01844,Q14C86 3 +Purpura 0.3312217277951019 0.4648739812869786 0.6420217040906495 1.0 0.7947215247553137 23 O00192,P04062,P38435,Q8NCH0,P21964,P51798,Q16625,P54198 8 +Vertebral hypoplasia 0.4143127271612942 0.4628641215534371 0.643461766139521 1.0 0.7955355028031232 9 P16278,Q96HY6 2 +Polyhydramnios 0.2954230959003854 0.4626363233245919 0.6436250679419442 1.0 0.7955355028031232 52 Q15125,Q70HW3,P04062 3 +Aplasia hypoplasia involving bones of the feet 0.2742852028594402 0.4620098526753149 0.6440742549231055 1.0 0.7955859152230221 77 P00813,P13073,Q9NX62,O95202,Q8WVQ1,Q8N3R9,Q9UHX1,Q7LGA3,Q13510,Q96A33,Q7RTS9 11 +Anorexia 0.3245505080892913 0.4612899920786448 0.6445905641601011 1.0 0.7955859152230221 28 Q14108,P04062,P01889,Q13423,Q9NZ08,P06280 6 +Pituitary growth hormone cell adenoma 0.3873260290198358 0.461278501182323 0.6445988072244924 1.0 0.7955859152230221 4 O00170,Q14697,P10644 3 +Muscle fiber atrophy 0.3320539709982786 0.4604323809500383 0.6452058967223557 1.0 0.7959134181495585 21 P61978,P50402,P35637,Q99720 4 +Central hypoventilation 0.4344360194584345 0.4592566772052322 0.6460498543469577 1.0 0.7965502825769402 7 O75306,P06753,Q8N183 3 +Abnormality iris morphology 0.2776173230561387 0.4590014378536651 0.6462331335404996 1.0 0.7965502825769402 87 Q9Y5Y5,P31749,Q05086,Q9NR77,O95202,Q86YV9,Q9UHX1,Q9H9S5,Q7LGA3,Q10713,Q9Y297,O43505,P40855,Q8WXW3,Q9Y4P3,P53701,O75381,Q96EK5 18 +Brisk reflexes 0.3310951350401729 0.4580183244177463 0.6469392763319131 1.0 0.796957511857871 22 Q10713,Q8NI60,P35637,Q99720 4 +Skin dimple 0.3241300553425167 0.4578240502026812 0.6470788556991129 1.0 0.796957511857871 28 Q08J23,P61978,Q15125,O95202,Q969X5,Q9Y4P3 6 +Abnormality of cardiovascular system electrophysiology 0.2642743580776822 0.4551996111493309 0.6489656402297219 1.0 0.7980152988886073 129 P09493,P01889,P42892,P00846,P40855,O75306,P00403,P31749,O75880,P36551,P07602,P50402,O75208,P0DP25,Q9Y5Y5,P04062,Q9Y4P3,Q9BUB7,O43464,O15460,Q9NZJ7,P03886,P10253,P22413,O75381,P06280 26 +Dysdiadochokinesis 0.3672536837969058 0.4536794507243742 0.650059559381009 1.0 0.7991494926357192 15 O75503 1 +Abnormal circulating fatty acid concentration 0.3310636089615766 0.4531937051274784 0.6504092648552711 1.0 0.7993684315820191 21 Q9Y5Y5,P09622,O75880,O75648,P40855,O43772,O75381 7 +Acantholysis 0.4135395439252795 0.4525878289407161 0.6508455644994933 1.0 0.7996936532415299 5 P01889,P98194 2 +Emotional lability 0.288258691671375 0.4517180693037839 0.6514720993321896 1.0 0.8002523836206064 57 P31749,Q92804,O75489,Q9NZJ7,Q13501,Q96CU9,P07602,Q68CQ7,O75306,P35637,Q15165 11 +Premature birth 0.2976703704553335 0.4491462860362878 0.653326132563373 1.0 0.8014730380511434 50 Q9Y5Y5,O43676,P04062 3 +Joint laxity 0.2739347296257803 0.4456987045031191 0.6558149005087359 1.0 0.8035018742886822 78 Q32P28,Q9Y619,P61978,P55795,Q8WVQ1,Q8NCH0,Q9UHX1,Q9HC07,Q96HY6,Q9NSD9,P16278,Q96A33,Q9Y487 13 +Biparietal narrowing 0.3869362578548758 0.441838439908303 0.6586061200304743 1.0 0.8056164146801337 11 Q8WXW3,Q10713,O75845 3 +Mandibular aplasia 0.4375207149146299 0.4321520623977075 0.6656308977813503 1.0 0.8122894215000077 6 P53701,Q9Y619 2 +Minimal change glomerulonephritis 0.3572943439169132 0.4316793158500129 0.6659745026856994 1.0 0.8124958704845436 16 Q8NFH4,Q14C86 2 +Abnormal large intestine physiology 0.3273962224268212 0.4306386647713611 0.6667311228829367 1.0 0.8130953753309281 22 O00192,Q9NZJ7,O75298,P07602,O43681,P54198,P20700,P06280 8 +Hypoplasia of teeth 0.3270994275408926 0.4284517683569824 0.6683222415207184 1.0 0.814506802983649 22 P51648,O75844 2 +Temporal pattern 0.4364281431388592 0.4275823198140063 0.6689552402904824 1.0 0.8150650037334729 6 Q9NR77 1 +High myopia 0.4065059413832319 0.4254652711228375 0.6704975332017069 1.0 0.815877092385985 9 Q9Y487 1 +Choanal stenosis 0.407309962828337 0.4251323085346257 0.6707402266820184 1.0 0.8159592519939518 5 P16435 1 +Vascular neoplasm 0.3074907735329655 0.4228179839538299 0.6724280654739403 1.0 0.816605018749876 39 P10619,P31749,O95202,Q9UHX1,Q7LGA3,O75874,P48735 7 +Reduced vital capacity 0.3463587921847189 0.4212125337708957 0.6735998927732898 1.0 0.8173035427293525 3 P06753,P35609 2 +Delayed puberty 0.2913509761085018 0.418172034670331 0.6758213407011837 1.0 0.8196277501853878 52 Q14108,P04062,O75844,Q9NVI7,Q15800,P06280 6 +Postnatal growth retardation 0.2769165428873227 0.4181090814258599 0.6758673654920726 1.0 0.8196277501853878 65 Q15125,O95202,P33991,Q7RTS9,Q9Y487 5 +Broad based gait 0.321806575762734 0.4163770475102656 0.6771341211709534 1.0 0.8207365954760085 26 O14773,P04062 2 +Ovarian cyst 0.3412792793791898 0.4161077983912681 0.6773311237482735 1.0 0.8207618039592763 18 P31749,P16435,Q03252,P31751,Q9Y4P3 5 +Coloboma 0.2873056635420311 0.4151192512425273 0.6780546071841669 1.0 0.8209977541626851 54 P31749,P78318,Q9NX14,P61978,O95202,Q9Y2B2,Q9UHX1,Q9H9S5,O43505,Q8IY17,Q8WXW3,P53701,Q10713,Q8N201,Q96EK5 15 +Narrow iliac wing 0.3769618004145557 0.4133257786491275 0.679367945367052 1.0 0.8221605324810934 4 Q9NR45,P50542,Q15436 3 +Abnormal circulating protein concentration 0.260471667352424 0.4115355880411951 0.680679851445376 1.0 0.8234844526273329 153 P07196,P09493,Q9BPX6,Q9H9S5,Q5XKP0,Q9NWM8,P22626,P36551,Q969X5,O43505,P50402,P14174,Q14C86,Q9Y487,Q8N511,P53985,Q08J23,Q9Y4P3,O95831,Q9NSD9,Q8NFH4,O95470,P31483,P10253,Q9HC07,Q8N1F7,Q96BR5,O14979 28 +Retrognathia 0.2705231258748827 0.4106198362520207 0.6813513162026774 1.0 0.8236736040171697 90 Q9Y619,P04062,Q15125,Q96DF8,Q8WVQ1,Q8NCH0,Q9UHX1,Q7LGA3,Q16625,Q4J6C6,O75844,Q71SY5,Q9BUB7,Q8N5M1,Q15392 15 +Tall stature 0.2827542598140718 0.4085810724669277 0.6828471232222029 1.0 0.8243737582789635 59 P31749,Q9NWM8,P61978,O95202,Q8N3R9,Q8NCH0,Q7LGA3,Q3ZCQ8,Q13423,Q9NSD9 10 +Abnormality of the gastric mucosa 0.3595320441036573 0.4077875732657992 0.6834296376407307 1.0 0.8245132550527686 15 Q14739,P04062 2 +Delayed closure of the anterior fontanelle 0.3707058111249498 0.4077786769787302 0.6834361695488922 1.0 0.8245132550527686 13 P40855,Q9Y487 2 +Exaggerated cupid s bow 0.4223673491610648 0.4065883523255704 0.6843103534419532 1.0 0.8253541238561932 7 Q71SY5 1 +Abnormality of the septum pellucidum 0.295999482977948 0.3995624480458453 0.689478819612185 1.0 0.8294801249468102 48 P51571,Q08J23,O95202,Q96N66,P53701,Q9H9S5,O43505,Q2M389,Q71SY5,Q15392 10 +Abnormal cry 0.3520053485737188 0.3993527630136211 0.6896332945726134 1.0 0.8294801249468102 16 Q13510,O75208 2 +Narrow mouth 0.2705305064800157 0.3992756483697087 0.6896901081835543 1.0 0.8294801249468102 78 P31749,Q9NX62,Q9Y619,P04062,P16435,Q8WVQ1,Q8N3R9,Q8NCH0,Q7LGA3,O75844,Q9NVI7,Q15392,Q9Y487 13 +Megalocornea 0.3637127787616986 0.3987515145400176 0.6900763060210449 1.0 0.829730364854421 14 O95202,Q9Y4P3,Q9H9S5 3 +Abnormal emotion affect behavior 0.2593310129933246 0.3983957903155533 0.6903384605001706 1.0 0.8298313674863985 240 Q15907,P50897,Q05086,P05023,Q15125,Q96CU9,P55795,P01889,Q6DKK2,Q01105,P00846,Q68CQ7,O75306,P17900,Q13510,P35637,P51572,P31749,Q96DF8,P07602,Q9NZ08,P54802,Q14C86,Q15067,Q92804,P04062,Q3ZCQ8,O95831,P61457,Q71SY5,O75503,O43464,Q8NFH4,Q15165,Q9NZJ7,O75489,Q13501,Q9H936,Q9UHX1,O43681,Q10713,P22413,P06865,Q8N1F7,Q05639 45 +Ventricular tachycardia 0.3452952148384197 0.3977714068385176 0.6907986958939032 1.0 0.8299761108511464 17 P46976,Q9BTV4,P09493,Q9NX14,O43772,P0DP25 6 +Abnormal spermatogenesis 0.3687824172391921 0.3972114453901278 0.6912115428090055 1.0 0.8299761108511464 13 Q13423,P16435,P04062 3 +Zonular cataract 0.3736740229443092 0.3967823457631145 0.6915279704193429 1.0 0.8299761108511464 12 P08670,Q8WWV3,Q9H6K4 3 +Slender long bone 0.3570335012259634 0.3931311373672702 0.6942226274767462 1.0 0.8325666835187137 15 Q9Y619,Q9Y487 2 +Congenital contracture 0.3020567864684604 0.3921748631673085 0.6949290157989898 1.0 0.8329538526342247 42 P04062,Q8NCH0,Q9H9S5,O75844,Q15392,Q96A33 6 +Myositis 0.3985158795064818 0.3879385967546828 0.6980614744425926 1.0 0.8342029732169592 9 P22626,P01889 2 +Hypertensive crisis 0.4179934199957738 0.3878942585305902 0.6980942871618092 1.0 0.8342029732169592 7 P54198,O00192,P01889 3 +Lower limb hyperreflexia 0.3368702159823326 0.3873075945979982 0.6985285037822555 1.0 0.8344977916961759 18 O60762,Q05086,P13073,Q14739,Q15041,Q9Y4W6,Q15233 7 +Limitation of joint mobility 0.2591909541768662 0.3870768567973278 0.6986993103510275 1.0 0.8344977916961759 107 P51648,Q05086,P01889,P48651,P15586,O75874,P16278,P31749,P16435,Q969X5,P48735,P50402,P54802,Q7LGA3,Q9Y4P3,O75844,P08236,O15460,P22413,Q9H6K4,O14979,Q7RTS9 22 +Thickened calvaria 0.3977217561669638 0.3842531688587886 0.7007908143494903 1.0 0.8363524502280107 9 Q15233,P16278,Q7RTS9,P48651 4 +Abnormality of the musculature of the upper limbs 0.2691610131599523 0.3806830566499793 0.7034384427382887 1.0 0.8389128166847893 78 P07196,O60313,P50402,P31483,Q9NR77,Q9NZJ7,Q9BQT8,P36551,P07602,Q9H9S5,O14979,Q9Y487 12 +Large basal ganglia 0.3285840830808467 0.3794818896544635 0.7043300503264467 1.0 0.8390902576805036 19 Q96N66,Q2M389,Q71SY5 3 +Abnormal heart valve physiology 0.2737680668099768 0.3789093267206176 0.7047551980266871 1.0 0.8391630007208699 83 P00813,P04062,P09493,Q15125,P01889,Q9UHX1,P53701,P22413,Q9Y4P3,O75844,O75306,P16278,Q9NZ08,P06280 14 +Abnormal serum insulin like growth factor 1 level 0.3374777975133174 0.3783556700514369 0.7051663949023068 1.0 0.8391630007208699 3 O00255,O00170 2 +Adrenocorticotropin deficient adrenal insufficiency 0.3374777975133174 0.3783556700514369 0.7051663949023068 1.0 0.8391630007208699 3 O00255,O00170 2 +Contractures of the joints of the lower limbs 0.2858303256398563 0.3777772410983281 0.7055960819896052 1.0 0.8391630007208699 53 O60762,Q8TD16,P48651,Q9H9S5,Q86XL3,P35637,Q99720,Q969X5,P21912,P50402,Q8IZA0,O60313,Q08J23,O75340,Q7LGA3,P06753,Q8N2K0,Q8IWS0,Q9BTV4,P23786 20 +Perimembranous ventricular septal defect 0.4062234579480062 0.3775562885650085 0.7057602418070741 1.0 0.8391630007208699 8 Q9UHX1,P0DP25 2 +Hemifacial spasm 0.3962288203533042 0.3774379884947966 0.7058481401512169 1.0 0.8391630007208699 5 Q10713 1 +Spastic diplegia 0.3183523731931386 0.3742850964018057 0.7081922189737377 1.0 0.8410911157520832 24 P51648,P35637,Q9NZJ7,P07602 4 +Vasculitis 0.4050227268627 0.3722703582796914 0.709691565844309 1.0 0.8422505523629534 8 Q9NZ08,P01889 2 +Large for gestational age 0.4048636423642407 0.3715714149418976 0.7102119752050182 1.0 0.8424159359574674 8 P31751 1 +Excessive wrinkled skin 0.3843078746996543 0.3708090370542437 0.7107797698897622 1.0 0.8428747882246722 10 Q9Y487 1 +Sparse or absent eyelashes 0.3146832016487626 0.3699803707886523 0.7113971161114128 1.0 0.8433921524171445 27 Q15125 1 +Skeletal muscle atrophy 0.2589408505361728 0.3619778893533042 0.7173685533840342 1.0 0.8478819390161967 168 P07196,Q6DKK2,O15269,Q9H9S5,Q68CQ7,Q13510,P35637,P16278,Q99720,Q9NWM8,P22626,Q9NR77,Q9BQT8,Q969X5,O43505,P50402,O60313,Q92804,O75298,Q6P4A7,O95831,Q71SY5,Q15165,Q8N2K0,P31483,Q9H0B6,Q9NVI7,Q96BR5,O14979 29 +Muscle fiber inclusion bodies 0.371096756756767 0.3602569206795803 0.7186550117174122 1.0 0.8491232919795296 11 O43676 1 +Mask like facies 0.3666873758837891 0.3600852088697341 0.7187834135412807 1.0 0.8491232919795296 12 Q9H9S5,Q05086,P04062 3 +Abnormal urine metabolite level 0.2584420135578884 0.3596892739860323 0.7190795140612114 1.0 0.8492577019516031 162 Q14108,P15586,Q9H9S5,Q5XKP0,P16278,P00403,O95721,P36551,P09601,Q4J6C6,P54802,Q14C86,P53985,P04062,Q96JX3,Q9Y4P3,Q3ZCQ8,P61457,Q9BUB7,P08236,O43464,Q8NFH4,O95470,P48637,Q9Y619,P03886,P04066,P10253,Q8N1F7,Q9H0P0,Q9H6K4,Q9NVI7,P06280 33 +Abnormal urine carbohydrate level 0.3616532404282762 0.3585424347259092 0.7199374174297959 1.0 0.8500553841287679 13 P10253,P04066 2 +Coronal craniosynostosis 0.4103970120974353 0.3559698739981972 0.7218631264494544 1.0 0.8510347868897895 7 Q6NUK1,Q9NX62,P16435 3 +Abnormality of the ankles 0.2963341039021614 0.354682553504469 0.7228274225719042 1.0 0.8519560056528164 44 O75298,Q9NZJ7,Q969X5,P07602,Q9Y4P3,O75844,O60220,Q7RTS9 8 +Abnormal lung lobation 0.3442998354014578 0.3530886415124839 0.7240219879435408 1.0 0.8527947340645884 16 P31749,O00192,Q14739,Q9UHX1,P54198 5 +Cone shaped epiphysis 0.3653213710621113 0.3530002241625278 0.7240882724829212 1.0 0.8527947340645884 12 O95831 1 +Short femur 0.3903336955981403 0.3527122710740046 0.7243041589077426 1.0 0.8528333600081559 5 Q9UHX1 1 +Turricephaly 0.3601736922791332 0.3506206886806116 0.7258729334003757 1.0 0.8538172029744824 13 O00192,P16435,P07237,Q6NUK1,P21964,P54198 6 +Vocal cord paralysis 0.3310912338621623 0.3500980328487692 0.726265127150681 1.0 0.8540628533874961 18 Q02978,Q9NR77,P43243,Q9BTV4,P21912,P50402,Q13642 7 +Lower limb asymmetry 0.3797232821416622 0.3488606775891973 0.7271939074387332 1.0 0.8544497781395021 10 P31749,P22413 2 +Abnormal atrioventricular valve morphology 0.2974484001369316 0.3474225579434865 0.728273888750764 1.0 0.8549142575103476 36 O00192,P04062,Q9NX14,P55795,P53701,Q9Y4P3,P22413,P54198,O75844,Q15233,O60826 11 +Abnormal circulating dicarboxylic acid concentration 0.2981123937214698 0.3470446819872008 0.7285577509857799 1.0 0.8549850388209088 41 P36551,P22695,O75845,Q9H9P8,P48735,P40855,Q9NSD9 7 +Fatty replacement of skeletal muscle 0.3984471972564838 0.3436588384749584 0.7311028699012441 1.0 0.8567705341021862 8 Q9H9S5,P22626,Q7Z406 3 +Generalized edema 0.3606695273603413 0.3410167273368892 0.7330909891344088 1.0 0.8576103950176527 4 Q9NSD9 1 +Adrenocortical carcinoma 0.3874407582938346 0.3407543102721679 0.7332885491203571 1.0 0.8576103950176527 5 P04637,P25054,O96017,P10644 4 +Patellar dislocation 0.3144936195948275 0.3406960997778679 0.7333323751299508 1.0 0.8576103950176527 23 O00192,Q9NX62,Q96PU5,Q15125,Q8WVQ1,Q9Y4P3,P54198 7 +Abnormality of t cell physiology 0.3359083367355467 0.3395552802655683 0.7341914602511665 1.0 0.8583995536771922 17 P00813,O00192,Q96DF8,P54198,Q9H0U3 5 +Falls 0.3973558318068254 0.3389667332418015 0.7346347911526632 1.0 0.8587023481026612 8 Q9BQT8,Q5T8D3 2 +Abnormality of the synovia 0.2642453708731698 0.338042543071302 0.7353311281839705 1.0 0.8593006510489049 91 P31749,O75718,P16435,O95202,Q8WVQ1,Q969X5,Q9UHX1,Q9H9S5,P22413,O75844,P16278,Q96A33,Q7RTS9,Q9Y487 14 +Recurrent acute respiratory tract infection 0.3283007696861992 0.335554479910351 0.7372068552649818 1.0 0.860413312910119 3 Q03519,Q03518 2 +Fragile skin 0.3961655036257934 0.3338681120034301 0.7384790833551012 1.0 0.8610351865502031 8 Q8NCH0 1 +Abnormal tendon morphology 0.2574443210398004 0.325584799827996 0.7447385140709786 1.0 0.8661652930193804 217 P07196,P50897,P42892,P15586,Q9H9S5,Q86XL3,Q13510,P35637,Q99720,Q9NR77,P16435,Q15041,Q8WVQ1,Q969X5,P50402,Q8IZA0,O60313,Q08J23,P04062,Q8NCH0,Q7LGA3,O95831,O75844,Q71SY5,Q9BUB7,Q15392,Q96A33,Q8N2K0,Q9Y619,Q9H0B6,P04066,Q7RTS9 32 +Abnormal atrioventricular valve physiology 0.2887302817279146 0.3252256678619401 0.7450102835691577 1.0 0.8662650775998842 48 Q9NX14,P09493,P04062,Q6NUK1,P01889,P53701,Q9Y4P3,O75844,O75306,Q9NZ08,P06280 11 +Aplasia hypoplasia of the clavicles 0.3386024175457803 0.3195808306735866 0.7492861077966488 1.0 0.8693760951889271 16 O75844 1 +Molar tooth sign on mri 0.4088515787395531 0.3166614908745113 0.7515004719231912 1.0 0.8709851202334473 6 Q8WXW3,Q10713 2 +Abnormality of the phalanges of the hallux 0.3994942654324603 0.3114502373378454 0.755458367695444 1.0 0.8731758220630453 7 Q2M1P5,Q8WVQ1,P49711 3 +Abnormality of circulating enzyme level 0.2518237990907992 0.3089105110728349 0.7573896009246603 1.0 0.8744961130078018 98 P07196,O60762,P09493,Q9BPX6,Q9H9S5,O43772,Q9NWM8,P22626,Q969X5,Q5JRX3,O43505,Q86U42,P50402,P50416,P53985,Q08J23,P42167,Q9Y4P3,O95831,P13473,P12235,P31483,Q9BTV4,Q13501,O75648,P10253,Q9HC07,Q96BR5,O14979 29 +Abnormality of the bladder 0.2561167616597752 0.3087211340780362 0.7575336659481495 1.0 0.8744961130078018 121 P07196,P61978,P01889,Q86XL3,P35637,Q99720,Q9NWM8,P31749,P22626,Q9NR77,P16435,P07602,P04062,O75298,Q8NCH0,Q9Y4P3,Q3ZCQ8,Q9NZJ7,Q13501,Q9UHX1 20 +Anarthria 0.4065752634919425 0.3079251420908035 0.7581392940862544 1.0 0.874978402342362 6 P35637 1 +Telecanthus 0.2949378502840727 0.3062729363252802 0.7593968434241685 1.0 0.8759942536071973 39 Q15125,O75844,Q8NCH0,Q86XL3 4 +Abnormal circulating tyrosine concentration 0.3216513811554243 0.3055724628126315 0.7599301896713682 1.0 0.8761769365072358 3 Q9NVS9 1 +Temperature instability 0.3891954612808118 0.3044222080466692 0.760806250600645 1.0 0.8768896743010326 8 P07602 1 +Hypoglycemic coma 0.3799889193552966 0.3042664881839073 0.7609248740929098 1.0 0.8768896743010326 9 Q13423 1 +Abnormality of hindbrain morphology 0.2552564722046982 0.302767413192281 0.762067118994884 1.0 0.8774627366954423 284 Q14108,Q15125,Q96CU9,P55795,Q6DKK2,Q9H9S5,P00846,Q9H9P8,Q5XKP0,P35637,P51572,Q99720,P31749,P16435,Q9GZY8,Q8IV08,O43505,O75208,Q9Y487,Q9Y5Y5,O60313,P13073,Q8NI60,Q96JX3,Q8WXW3,Q9Y4P3,Q16625,Q96D71,O75503,O14773,Q8NFH4,Q8N2K0,P98175,P46977,Q96BR5,O95202,Q13501,P00374,Q9H936,O75845,Q10713,O43292,Q9H6K4,Q9NVI7,Q9UNW9 45 +Renal tubular dysfunction 0.2942372171915019 0.2998776142176202 0.7642705102280132 1.0 0.879270656920878 39 P50416,Q8N183,Q9NPL8,O75489,P03886,Q96CU9,O43676,P40855,O75306,Q86Y39,P00403 11 +Mixed hearing impairment 0.3961869389488281 0.2982699461190789 0.7654971404213482 1.0 0.8795798523260722 7 Q9NWM8,P22413 2 +Persistent head lag 0.3961776331990992 0.298233083636465 0.7655252729347137 1.0 0.8795798523260722 7 Q5XKP0,Q9NSD9 2 +Shield chest 0.4038936147521755 0.2977235747111013 0.7659141489109271 1.0 0.8796010822630577 6 Q7RTS9 1 +Fused cervical vertebrae 0.3957430494798966 0.296512991967202 0.7668383466792488 1.0 0.8804370270722063 7 Q9UHX1 1 +Atrophic scars 0.3949836299503281 0.293513829692224 0.7691294301955716 1.0 0.8817634471698185 7 Q8NCH0 1 +Aplasia hypoplasia of the optic nerve 0.3047738121963097 0.2927968311401543 0.7696774505476398 1.0 0.8821745976011088 27 P07196,O95721,P61978,Q9UHX1,Q9H9S5,Q9H3H1,Q9NVI7 7 +Abnormal anatomic location of the heart 0.3568649066376197 0.2903044411132399 0.7715833415635018 1.0 0.8836311534565211 11 Q10713,O75844 2 +Aplasia hypoplasia involving bones of the thorax 0.2923377768926826 0.2873370746361737 0.7738542375183373 1.0 0.8852984651408289 40 Q9Y619,P16435,Q9UHX1,Q96HY6,O75844,Q7RTS9,P98175 7 +Abnormality of the hallux 0.2713769719053202 0.2872466973873399 0.7739234328152544 1.0 0.8852984651408289 60 P31749,P04062,Q15125,O95202,Q8WVQ1,Q8N3R9,Q9UHX1,Q7LGA3 8 +Hemiplegia hemiparesis 0.2921834743381523 0.2859220626223977 0.7749378153113824 1.0 0.8860716604538186 40 P31749,P03886,P01889,Q9H9S5,P22413,Q9NZ08,P00403 7 +Abnormally large globe 0.3755843449515152 0.2851429264599127 0.775534643955182 1.0 0.8864884347345369 9 Q9H9S5 1 +Male reproductive system neoplasm 0.3320567655133473 0.2818943502721913 0.778024521767952 1.0 0.8884427398967417 16 P31749,Q01844,Q13423 3 +Temporal cortical atrophy 0.3464613562333317 0.2814937071940158 0.7783317539729859 1.0 0.8884427398967417 4 O43924,P00387,Q9UQN3 3 +Hereditary nonpolyposis colorectal carcinoma 0.3745617842357561 0.2807489806521603 0.7789029378100412 1.0 0.8885941426204192 9 P31749,P25054,Q07812 3 +Abnormality of the liver 0.2536372839682079 0.2797335739260722 0.779681917947133 1.0 0.889047337526988 306 P10619,P00813,Q14108,Q96CU9,P15586,P00846,Q96HY6,O43676,P40855,O75306,Q5XKP0,Q13510,P16278,O15118,P22626,O75880,P36551,P09601,P22830,Q14739,P07602,P61916,Q86Y39,P14174,P54802,Q9Y5Y5,Q8N511,Q15067,P04062,P31751,Q9Y4P3,Q16625,Q71SY5,Q9NSD9,Q9BUB7,P08236,Q8N5M1,P33991,Q96A33,Q9Y619,Q9NZJ7,O75489,O95202,P03886,P00374,P04066,O75845,P10253,Q9HC07,Q10713,P22413,Q01844,Q9BW92,Q9NVI7,O75381 55 +Abnormal blood gas level 0.3152753108348073 0.2776986561277257 0.7812436922927997 1.0 0.8901744419520207 3 P06753,Q9Y3E5 2 +Multiple joint contractures 0.3061541547033384 0.277145972152281 0.7816680231313662 1.0 0.890200334006734 20 Q9H0B6,O75844 2 +Abnormality of primary teeth 0.3362734441503438 0.275630453396101 0.7828319169575813 1.0 0.891112186996191 15 P61978,O75844,P53634 3 +Skin pit 0.341073513312337 0.2748729426363908 0.7834138553680225 1.0 0.8913884758185661 14 P61978,O95202 2 +Athetosis 0.3308092230481505 0.2748163085113983 0.7834573679693451 1.0 0.8913884758185661 16 O00584,O14949 2 +Rotary nystagmus 0.3704345577036241 0.272997587749187 0.7848550698692334 1.0 0.8921071047952389 5 Q5T8D3 1 +Bilateral ptosis 0.3406207946204391 0.2724957328948517 0.7852408718406401 1.0 0.8923278802229084 14 O60313,Q9UNW9,O75306 3 +Gowers sign 0.3401283573737416 0.2699148739786033 0.7872257439603274 1.0 0.8940042293228146 14 P07196,O75340,Q8TD16,Q5T8D3,Q13510 5 +Incomplete penetrance 0.2937613858908031 0.2698289743882113 0.7872918309751364 1.0 0.8940042293228146 31 O14979,P00846,P03886,P36551 4 +Pectus excavatum 0.2640471080451201 0.2671865048752151 0.7893255661211467 1.0 0.8956585839201708 82 P31749,P50402,O75718,Q08J23,P04062,P61978,Q8NCH0,Q9UHX1,Q7LGA3,Q9Y4P3,Q9NSD9,Q96A33,Q9Y487,P98175 14 +Abnormality of facial musculature 0.2638577888271778 0.2646489942309678 0.7912798734289828 1.0 0.8972204601831065 82 Q9Y5Y5,Q15907,P07196,P31749,O60313,P04062,Q9BQT8,Q13501,P48651,Q9UHX1,Q9H9S5,P10253,P40855,Q13510,O75381 15 +Abnormal middle phalanx morphology of the hand 0.3787851851559978 0.2618249847616538 0.7934563757633681 1.0 0.899250559198484 8 Q9UHX1,Q15233,P48651 3 +Uveitis 0.3700155048281058 0.2614291270304 0.7937615976976189 1.0 0.8993776507116295 9 P14174 1 +Oculogyric crisis 0.3504669149768071 0.2600491914846478 0.7948258291640764 1.0 0.9002487467347329 11 Q01105,Q05639 2 +Eeg with focal epileptiform discharges 0.2887150584155288 0.2595490665049587 0.7952116290753493 1.0 0.9002487467347329 41 Q05086,Q08J23,Q9UBX3,Q96N66,Q9H936,Q2M389,Q71SY5,O75503 8 +Alopecia 0.285503788042911 0.2594300114723677 0.7953034763446598 1.0 0.9002487467347329 45 P00813,Q15125 2 +Abnormality of the periorbital region 0.2554654351047117 0.2576805395191214 0.7966534662494786 1.0 0.9011199236984146 73 Q9Y5Y5,Q08J23,P16435,Q7LGA3,Q8N1F7,P40855,Q8NFH4,P38159,O75381,P98175,Q14C86 11 +Supernumerary nipple 0.3459608727978646 0.2561391215603976 0.7978434146789288 1.0 0.9020278217413716 12 P61978,Q7LGA3,Q8IY17,Q9Y2B2 4 +Peptic ulcer 0.3454250889848361 0.2535612266716632 0.7998345544301619 1.0 0.9029639734696302 12 P04062 1 +Unilateral renal agenesis 0.3019624321610088 0.2498405823059514 0.8027106345694446 1.0 0.9052220391445752 22 Q9UHX1,Q7LGA3,Q86XL3 3 +Multiple enchondromatosis 0.3907793074738139 0.2493154066928702 0.8031168147098084 1.0 0.905352885507814 6 P48735 1 +Abnormality of skin pigmentation 0.2508834369734268 0.2484364253477298 0.8037967534328998 1.0 0.9056810056822564 141 P51648,Q05086,Q15125,O00571,P00403,P16615,P31749,P53634,P36551,Q14739,P07602,Q8IZA0,Q08J23,P04062,Q8N3R9,Q86YV9,Q7LGA3,O75844,P33991,Q15555,Q9NZJ7,P03886,P53701,Q13423 24 +Opisthotonus 0.3003020132580941 0.2468157855111056 0.8050507932988462 1.0 0.9061804831186836 25 P04062,Q9NZJ7,P11117,P07602,P35637,Q99720 6 +Smooth muscle antibody positivity 0.2790766498964278 0.2464585591607555 0.8053272801624964 1.0 0.9061804831186836 2 Q96J02 1 +Abnormality of the urinary system physiology 0.2527491002078038 0.2463551787725179 0.805407299293978 1.0 0.9061804831186836 281 P00813,Q13277,P05023,Q14108,Q96CU9,P01889,P15586,Q9P0J1,P00846,Q9BT22,Q9H9P8,Q9H9S5,O43676,P40855,O75306,Q5XKP0,P16278,P00403,O95721,O75880,P36551,P09601,Q9BQT8,P49257,P51809,P48735,Q4J6C6,Q96EY8,Q86Y39,Q9NZ08,P54802,Q14C86,P50416,P53985,P04062,Q8NCH0,Q96JX3,Q9Y4P3,Q3ZCQ8,P61457,Q16625,Q9NSD9,Q9BUB7,P08236,O43464,Q8NFH4,Q8N5M1,O95470,P48637,Q9Y619,O15460,O75489,P03886,P04066,P10253,Q10713,P22413,Q8N1F7,Q13423,Q9H6K4,Q9H0P0,Q9NVI7,P06280 63 +Increased total bilirubin 0.3374876344215226 0.2458190306964571 0.8058223246381957 1.0 0.9063644984467744 4 P23786 1 +Back pain 0.3009041449785608 0.2443026889261324 0.8069964011002202 1.0 0.9070919971826316 23 P31749,P36551,Q9BTV4,P01889,P51798,Q9UGP8,P50402,Q969G3 8 +Bifid scrotum 0.374196736687125 0.2436117620170734 0.8075315179357863 1.0 0.9074745019408668 8 P16435 1 +Typical absence seizure 0.3298850803391762 0.2412364686443719 0.8093718474795315 1.0 0.9089177751740808 15 P61978,Q13510,Q05639 3 +Abnormality of the antihelix 0.3428430110634587 0.2412218583251091 0.8093831705351868 1.0 0.9089177751740808 12 P16435,P98175 2 +Widened subarachnoid space 0.296961661047567 0.2411985554394919 0.8094012304469915 1.0 0.9089177751740808 28 P03886,O95831,P00403 3 +Irregular menstruation 0.3875555555555589 0.237811736890911 0.812027115070781 1.0 0.911646734634779 6 O75616,O00170,Q06787,P10644,P02545 5 +Urinary retention 0.3352087651761877 0.2370135247410256 0.8126462979411577 1.0 0.9119809561355218 4 P20700,P54886,P08397 3 +Nausea and vomiting 0.2509190070756822 0.236923174740522 0.8127163909228319 1.0 0.9119809561355218 150 P61978,Q96CU9,P01889,P42892,P00846,Q68CQ7,O43676,O75306,P35637,P00403,P31749,P36551,P11117,P07602,Q8IZA0,Q86Y39,Q9NZ08,P51571,Q92804,Q9Y4P3,Q9NSD9,O43464,Q15165,Q9Y619,Q9NZJ7,O75489,P03886,P22695,P22413,Q01844,Q13423,P06280 32 +Short ribs 0.3450919944133017 0.2352595461400713 0.8140072914964285 1.0 0.9132095288512436 11 Q14739,Q7Z4L5,Q96HY6,Q9Y619 4 +Meningocele 0.3413747528354968 0.2342684463161923 0.8147765805654958 1.0 0.91363247767792 12 O00192,O75845,Q9H9S5,Q10713,P54198 5 +Hydrops fetalis 0.2795660589042013 0.233640431954364 0.8152641361616779 1.0 0.9138582320605116 48 P10619,P04062,Q14739,P16278,P22413,P08236,Q13510 7 +Unsteady gait 0.2723853599519331 0.2335037082764411 0.8153702903485371 1.0 0.9138582320605116 53 Q9NR77,Q10713,O95831,Q9H6K4,O75503,Q05639 6 +Sparse lateral eyebrow 0.3790776397998928 0.2327339880277529 0.8159679751701026 1.0 0.9142369415314184 7 P61978,Q08J23 2 +Abnormality of circulating adrenocorticotropin level 0.3439024380142051 0.2298541243871251 0.8182051253081992 1.0 0.9161537196359596 11 P31749,Q13423 2 +Focal onset seizure 0.258782363644543 0.2265417804019621 0.8207800676765857 1.0 0.918154071863001 89 P31749,Q08J23,Q9NZJ7,Q9UBX3,P03886,Q96N66,Q9H936,Q01105,P07602,Q2M389,Q71SY5,O75503,Q05639,P00403 14 +Synostosis of joints 0.2832643848819492 0.2234631662923891 0.8231750473583657 1.0 0.9199811229002438 37 P16435,O95202,Q8WVQ1,Q9UHX1,Q9H9S5,Q9Y4P3,P22413 7 +Abnormality of prenatal development or birth 0.2505899077670079 0.2224357615421343 0.8239746753550863 1.0 0.9199811229002438 254 P10619,P61978,Q15125,Q96CU9,O43676,P40855,O75306,Q13510,P16278,O15118,Q70HW3,O75718,P16435,Q14739,Q969X5,P61916,Q4J6C6,Q86Y39,Q9Y487,Q9Y5Y5,O60313,P0DP25,P04062,Q7LGA3,Q9Y4P3,O75844,Q9NSD9,Q9BUB7,P08236,P33991,Q9Y619,O75489,O95202,P03886,Q9UHX1,P22413,Q9NVI7,Q05639,O75381 39 +Abnormal erythrocyte morphology 0.2526835650242724 0.2223524556744027 0.8240395202421373 1.0 0.9199811229002438 196 P00813,Q14108,Q96CU9,P01889,O75874,O75306,Q13510,P00403,P36551,P09601,P22830,Q9UBX3,Q9BQT8,P07602,P48735,O60313,P04062,Q6P4A7,Q9NSD9,P48637,Q9NZJ7,P03886,P00374,O75845,Q01844,Q9H0P0,P06280 27 +Bowel diverticulosis 0.3604204164908806 0.2218640791617911 0.8244196943199318 1.0 0.9200160364499862 9 P31749 1 +Abnormal motor nerve conduction velocity 0.2976269776084501 0.2205252184321449 0.825462134290216 1.0 0.9207381756522572 21 P07196,Q9NR77,Q71SY5 3 +Dental crowding 0.2959138627936938 0.2199805407779708 0.8258863097244136 1.0 0.9209907662667748 26 Q96A33,O75844 2 +Prenatal maternal abnormality 0.337393607439612 0.215651353104307 0.829259523492442 1.0 0.9240086555796706 12 Q14739,P50416,P16435 3 +Abnormality of earlobe 0.2945131702347076 0.2154890567067296 0.8293860431469735 1.0 0.9240086555796706 27 O00192,P16435,Q9NX14,P53701,Q7LGA3,P54198,P10586,Q15392,P98175 9 +Abnormal urinary electrolyte concentration 0.3021259733868532 0.2094647414185023 0.8340854571227494 1.0 0.9279600233219096 19 Q9Y4P3,Q13423,P22413 3 +Preaxial polydactyly 0.318939101463891 0.2092995576873501 0.8342143970454678 1.0 0.9279600233219096 16 O95202 1 +Hip dysplasia 0.2683881728141365 0.209154919530939 0.8343273030640099 1.0 0.9279600233219096 54 Q15125,O95202,Q8N3R9,Q9UHX1,Q7LGA3,Q9NVI7,Q96A33 7 +Weakness of facial musculature 0.2617854549673799 0.208835648002607 0.8345765417599957 1.0 0.9280156437140272 63 P07196,P31749,Q9Y5Y5,O60313,Q9BQT8,Q13501,P48651,Q9UHX1,Q9H9S5,P40855,Q13510,O75381 12 +Chromosome breakage 0.3356810247531789 0.2077518312709113 0.8354227449944047 1.0 0.9286588270716504 12 P33991,P13073 2 +Vitreous floaters 0.2981761925733461 0.2075841233374082 0.8355537020732688 1.0 0.9286588270716504 3 P04439 1 +Flared metaphysis 0.3645679818361648 0.2065898019317725 0.8363302253378628 1.0 0.9293001406545242 8 Q14739,Q96HY6,P48651 3 +Iris coloboma 0.2823256651194098 0.2041483106466439 0.8382376027576162 1.0 0.930292907255439 38 P78318,O95202,Q9UHX1,Q9H9S5,Q8WXW3,Q8IY17,O43505,P53701,Q10713,Q96EK5 10 +Proximal muscle weakness in lower limbs 0.31270844668599 0.2037262569935725 0.8385674223708066 1.0 0.930292907255439 17 P07196,P12235,P50402,P36551 4 +Tremor by anatomical site 0.2899994187480632 0.2036567934031135 0.8386217083653045 1.0 0.930292907255439 29 P07196,Q05086,Q9NR77,P56192,Q9Y4W6,Q9UNE7,P20700,P35637,Q99720 9 +Abnormal coronary artery morphology 0.3704414004879253 0.2014763545702 0.840326116652697 1.0 0.9310002313352052 7 P22413 1 +Pituitary adenoma 0.3306038970492266 0.201092715841205 0.8406260775756216 1.0 0.9310002313352052 13 P48735 1 +Recurrent fractures 0.287525640949472 0.2010513384147327 0.8406584313001015 1.0 0.9310002313352052 30 O75718,Q32P28,P16435,Q13501,P51798,O75874,P48735 7 +Orofacial dyskinesia 0.3698026973023415 0.1992164955413767 0.842093396460682 1.0 0.931924694871432 7 Q9BPX6 1 +Abnormal sputum 0.3751675525754824 0.1951655725641967 0.8452633298948777 1.0 0.9340827062417648 6 P01889 1 +Abnormal subarachnoid space morphology 0.2821796281194595 0.1940086159885507 0.8461691355005099 1.0 0.9346587225898446 32 P03886,O95831,P00403 3 +Cerebral hamartoma 0.3233443212728591 0.1929319715375141 0.8470122457377243 1.0 0.934924891148417 4 O43924,P49815 2 +Broad toe 0.2796116848032258 0.1907726305234514 0.8487037325226727 1.0 0.936126447096995 33 Q9UHX1,Q15125,Q7LGA3 3 +Periauricular skin pits 0.3317289677114802 0.1897807305545721 0.8494809562642729 1.0 0.936761906789532 12 O95202 1 +Abnormality of the auditory canal 0.2916557333027869 0.1893860100781625 0.8497902884003539 1.0 0.9367918504416712 26 Q9H9S5,Q9Y619,O95202 3 +Multiple lipomas 0.3662295432034497 0.1867095742332997 0.8518883489582636 1.0 0.9383059658187732 7 P22413 1 +Arterial stenosis 0.3190962131177176 0.1853588189787774 0.8529476063583137 1.0 0.9392505792948048 15 P22413,P01889 2 +Sporadic 0.2909547286089862 0.1844047024501998 0.853695981059037 1.0 0.9396304063735808 26 P31749,Q05086,P04062,Q9BWD1,O95202 5 +Aplasia hypoplasia of the hallux 0.2918495765277804 0.1829097134302798 0.8548688612607609 1.0 0.9404768908248996 23 Q9UHX1,O95202,Q7LGA3 3 +Slender build 0.3329365630372748 0.1814856033036819 0.8559864324152429 1.0 0.94103960400996 11 Q15233,Q3ZCQ8,Q9NSD9 3 +Disinhibition 0.2622703675277698 0.1759144736235415 0.8603611343663706 1.0 0.9451797556317344 59 Q08J23,P04062,Q96N66,P05067,Q2M389,Q71SY5,Q05639,O43464,P35637 9 +Abnormality of adrenal morphology 0.2889021938206194 0.1745398405579331 0.8614412230226092 1.0 0.9461431777503688 27 P22413,O75874,O75844,P48735 4 +Intellectual disability moderate 0.256923968075309 0.172762090217746 0.8628384365307231 1.0 0.9472310717322904 82 P31749,Q08J23,P61978,Q15125,Q8NI60,Q96N66,Q01105,Q9UHX1,Q10713,Q2M389,Q4J6C6,Q71SY5,Q05639,P38159 14 +Lower extremity joint dislocation 0.2587397344771889 0.170064780991606 0.8649591906951151 1.0 0.9488012739254008 85 Q9NX62,Q8TD16,Q96PU5,Q15125,Q9Y2B2,P21964,Q9H9S5,Q9NSE4,P31749,Q8WVQ1,Q969X5,Q9Y487,O00192,P62258,Q9Y4P3,P54198,O75844,Q96A33,O95202,Q9UHX1,Q8NBU5 21 +Hydrocephalus 0.2558732468384168 0.1699066967429009 0.8650835144613949 1.0 0.9488012739254008 81 Q15125,P48651,Q9H9S5,P40855,P31749,P16435,Q9NX14,Q6NUK1,P51798,O43505,O00192,Q08J23,P04062,Q8WXW3,P54198,P08236,Q15392,O95202,P53701,Q10713,P23786,P07942,O60826 23 +Telangiectasia of the skin 0.2885664140647592 0.1646319076820153 0.8692337151877001 1.0 0.9524560445411212 20 Q8IZA0,P22413,P06280 3 +Limited elbow extension 0.3258187184692589 0.1636022320928495 0.870044287427961 1.0 0.952805715660756 12 Q7RTS9,Q9H6K4 2 +Aplasia hypoplasia of the lungs 0.2762788228142288 0.1635447045472985 0.8700895777964437 1.0 0.952805715660756 33 O75844,P98175 2 +Angiofibromas 0.3584290356226471 0.1602262369053292 0.8727028623256659 1.0 0.9551339127615016 7 P31749,P21912,P49815 3 +Adenoma sebaceum 0.3584290356226471 0.1602262369053292 0.8727028623256659 1.0 0.9551339127615016 7 P31749,P21912,P49815 3 +Petechiae 0.3248707257506119 0.1594835225557084 0.8732879392592845 1.0 0.9553300920224244 12 Q16625,P04062 2 +Abnormal mitochondrial morphology 0.3245546472840577 0.1581153024598453 0.8743659426735055 1.0 0.9562800096203776 12 P46976,Q13501,Q9GZY8,P35637 4 +Abnormality of upper limb epiphysis morphology 0.3090150730273849 0.1573189501167239 0.8749934861825004 1.0 0.9566570390055648 16 O95202 1 +Abnormal patella morphology 0.2775557493316774 0.157014197633789 0.8752336587973559 1.0 0.9566570390055648 32 Q9NX62,Q9Y619,Q15125,Q8WVQ1,Q9Y4P3 5 +Short long bone 0.2777724217296219 0.1538833667667667 0.8777016992799593 1.0 0.9588026536693364 39 Q9UHX1,Q96HY6,P16278,Q7RTS9,P98175 5 +Congenital onset 0.245418166916924 0.1526667731525433 0.8786610647302191 1.0 0.9591758236497212 111 Q8TCJ2,Q8TD16,Q96PU5,Q15125,Q96D09,P20674,Q9H9S5,Q5XKP0,P78318,Q9NX14,Q6NUK1,Q969X5,P07602,O43505,Q4J6C6,O43924,P51571,Q66GS9,P08670,Q7LGA3,Q71SY5,Q9BUB7,Q8NFH4,Q96EK5,P46977,P12235,Q9NZJ7,Q96N66,Q03252,Q9BW92,Q9UHX1,Q9Y263 32 +Intestinal malrotation 0.2790110044234114 0.1520403451925356 0.879155114671405 1.0 0.9594902821320066 31 O00192,Q14739,O95202,Q8NCH0,P21964,P54198,Q9NSD9,O60826,Q15392 9 +Abnormality of renal excretion 0.3489540361300648 0.1502761323763928 0.8805467627438617 1.0 0.9605589744404937 8 P22413,P05023 2 +Cutis laxa 0.2785033228006454 0.1481196870382962 0.8822483128096938 1.0 0.9615841732482474 31 Q9NX14,P38435,Q8NCH0,P48651,Q9Y4P3,Q9Y487 6 +Increased muscle lipid content 0.3330257769210714 0.1465373519272907 0.8834972055778747 1.0 0.962226050266322 10 Q8NI60,O75648,Q9Y4W6,P06753,P23786 5 +Neoplasm of the adrenal gland 0.315167392578471 0.146507208472558 0.8835209997829667 1.0 0.962226050266322 14 P25054,O75874,Q02978,P48735 4 +Long toe 0.3328469322031098 0.1458496667553895 0.8840400666806438 1.0 0.9625161005191392 10 Q9UHX1,O60762,P23786 3 +Abnormal vascular morphology 0.2475985247020175 0.1452926961511894 0.8844797811634537 1.0 0.9625374923438558 237 P10619,Q96PU5,P61978,P01889,P42892,P00846,P40855,P17900,Q13510,P16278,Q9NWM8,O15118,O75718,P31749,Q96DF8,P05067,P07602,P61916,Q9NZ08,Q9Y487,P0DP25,P51571,P04062,P38435,Q8N3R9,Q7LGA3,Q9Y4P3,O75844,Q71SY5,Q9NSD9,P08236,Q15392,P98175,O15460,Q9NZJ7,P03886,O75845,Q9UHX1,P10253,P22413,P53701,P06865 42 +Leukodystrophy 0.2600809507544371 0.1447879861698279 0.8848782679169058 1.0 0.962578928528012 58 Q9Y5Y5,Q15067,O75489,Q9NZJ7,P03886,Q96CU9,P07602,O43676,O75306,Q86Y39 10 +Abnormal synaptic transmission at the neuromuscular junction 0.279922125482606 0.1427998341919583 0.8864482680351786 1.0 0.9640616466280324 30 Q92804,Q13501,Q9H9S5,Q68CQ7,P35637,Q15165 6 +Lymphedema 0.3060524905108996 0.1423428979183915 0.886809163836491 1.0 0.96422901147301 16 Q14739,P31749,P06280 3 +Difficulty running 0.3139655821373939 0.1409682160220364 0.8878950515026838 1.0 0.9648844707616684 14 P07196,Q9BPX6 2 +Death in childhood 0.2851030899022794 0.140793052142176 0.8880334319783754 1.0 0.9648844707616684 25 Q8TCJ2,O95721,Q9NPL8,P20674,Q9H936,Q9H9S5,Q96IX5 7 +Decreased circulating cortisol level 0.3313577941797735 0.1401529901966766 0.8885391135961154 1.0 0.9652087665883174 10 P31749,Q13423 2 +Dysphasia 0.284834395517919 0.1394795778799689 0.8890711926783319 1.0 0.9655615797378572 21 O00192,Q9NX14,Q13501,P53701,Q9H9P8,P54198 6 +Hypocalcemia 0.3003002996745033 0.1368646578937284 0.8911377748127762 1.0 0.966823711110429 17 O00192,Q96DF8,P51798,P54198,Q4J6C6,Q9NSD9 6 +Abnormal t wave 0.3311211452733767 0.1358996849895535 0.8919005845077037 1.0 0.9672812392635352 5 P46976,P0DP25 2 +Fibroadenoma of the breast 0.3304538995352643 0.1338399416678421 0.8935291424323903 1.0 0.9688218681215256 5 P31749 1 +Puberty and gonadal disorders 0.2463583311366917 0.1322274362709595 0.89480440064311 1.0 0.9699125264864924 161 Q14108,Q16740,P48651,Q9BT22,O75874,P00403,P31749,O95721,P16435,P48735,Q15800,Q4J6C6,O60313,P04062,Q8N3R9,Q7LGA3,Q9Y4P3,O75844,O95470,Q15555,O95202,P03886,Q9H936,Q13423,Q9NVI7,P06280 26 +Abnormal shoulder morphology 0.2725381180379534 0.1320414711609625 0.8949514896605719 1.0 0.9699125264864924 34 Q9Y619,Q8N3R9,Q9Y4P3,Q7LGA3,P22413,Q7RTS9 6 +Abnormality on pulmonary function testing 0.2835345186948657 0.1297449430868565 0.8967682236268488 1.0 0.971429392012526 22 Q9BQT8,Q9H9S5,P16278,P01889 4 +Pectus carinatum 0.2720887217413664 0.1284280343273605 0.89781024666937 1.0 0.9723320458000292 34 Q9Y619,P55795,Q9NVI7,Q71SY5,P16278,Q7RTS9 6 +Hypopigmented macule 0.3284952606634999 0.1278492177920641 0.8982682994607385 1.0 0.972601984864742 5 O00255,Q15233,Q9H488,P49815 4 +Gastrointestinal obstruction 0.3106434893573647 0.1258683010240807 0.8998361751919717 1.0 0.973846864322538 14 P42892 1 +Cholecystitis 0.3411506941613915 0.1239896513755532 0.9013234688399244 1.0 0.9752298996182038 8 P07602,Q9NZJ7 2 +Abnormality of facial soft tissue 0.2452449880078669 0.1223693173028978 0.9026065371062936 1.0 0.976150689235122 126 P07196,Q15907,P48651,Q9H9S5,P40855,Q13510,P31749,P16435,Q9BQT8,Q14C86,Q9Y5Y5,O60313,P04062,Q9Y4P3,O75844,Q8NFH4,Q13501,Q9UHX1,P10253,Q8N1F7,O75381 21 +Nephrolithiasis 0.2814856105781375 0.1221589535429951 0.9027731332543164 1.0 0.976150689235122 20 Q4J6C6,Q8NCH0 2 +Cupped ear 0.306090036921125 0.1221210253020043 0.9028031707223928 1.0 0.976150689235122 15 Q15392,P78318,P42892 3 +Aplasia hypoplasia affecting the fundus 0.2748432890597897 0.1201497506218983 0.9043645225090576 1.0 0.9773163837217612 31 P07196,O95721,P61978,Q86YV9,Q9UHX1,Q9H9S5,Q9H3H1,Q9NVI7 8 +Aplasia hypoplasia of the 5th finger 0.2970183291088079 0.1199651948976986 0.904510719240986 1.0 0.9773163837217612 17 Q9UHX1 1 +Abnormal head movements 0.3169351611352942 0.1160397149450887 0.90762106640802 1.0 0.9800794797108738 11 P35637 1 +Abnormality of the fetal cardiovascular system 0.3445488594416728 0.1160255415404717 0.9076322992763868 1.0 0.9800794797108738 7 Q9Y2B2,P16435 2 +Peritonitis 0.296226711967579 0.1159411275448456 0.9076992004020416 1.0 0.9800794797108738 17 Q8NFH4,Q14C86 2 +Weight loss 0.2433556038665471 0.1150086506205877 0.9084382653413892 1.0 0.9806501598980744 72 P31749,P04062,Q9NZJ7,P01889,P42892,P07602,Q01844,Q13423,O75844,P35637,Q9NZ08,Q99720 12 +Ovarian neoplasm 0.2809227872856419 0.1136634089198008 0.9095046199342977 1.0 0.9815325369548222 22 P31749,Q01844,O75874,P48735 4 +Tonic seizure 0.279535899447636 0.1086059602730478 0.9135150331079962 1.0 0.9854453506755548 27 Q9NZJ7,Q9H936,Q01105,P07602,Q05639,Q8TAB3 6 +Impaired distal vibration sensation 0.3466666666666692 0.1073479998171099 0.9145129061649429 1.0 0.9862933820134994 6 P54886,Q96RR1,Q6UWE0,Q06787,P20700 5 +Early onset of sexual maturation 0.2681678745830111 0.1061475659095126 0.9154652721542916 1.0 0.9870919531700674 46 O95202,Q8N3R9,Q9H936,Q9Y4P3,Q7LGA3,O75874,P48735,Q13423 8 +Restrictive ventilatory defect 0.3112383738831066 0.1028506697210521 0.918081489840511 1.0 0.9896837722002084 12 Q9H9S5,P01889 2 +Pseudobulbar signs 0.3127364941640261 0.0999596360084348 0.9203763706891632 1.0 0.9919280737320968 11 Q15233,P17900 2 +Aplasia hypoplasia involving the nose 0.2775292337621245 0.0987464170663623 0.921339613445734 1.0 0.9925069193871946 28 P61978,Q96DF8,P55795,O75844 4 +Bilateral polymicrogyria 0.326843611277644 0.0981310514606444 0.9218282310125488 1.0 0.9928036763136304 9 Q05639 1 +Abnormal platelet volume 0.332851914378177 0.0974766518702702 0.9223478750284392 1.0 0.9931337036251664 8 O75845 1 +Abnormality of the cerebral subcortex 0.234755623014914 0.0964778896094427 0.9231410335350074 1.0 0.9937580157628992 389 Q05086,Q96PU5,P61978,Q15125,Q96CU9,Q9BPX6,Q01105,P48651,Q9H9S5,P00846,Q9H9P8,Q9P0J1,Q86XL3,O75306,P17900,P16278,P51572,P00403,O95721,Q9UBX3,Q9GZY8,P07602,O43505,Q2M389,Q9Y5Y5,O60313,P51571,Q08J23,Q15067,P04062,Q8NI60,Q8N3R9,Q8WXW3,Q7LGA3,Q3ZCQ8,O95831,Q96D71,Q71SY5,O75503,Q9BUB7,O43464,O60220,Q15392,Q96A33,P98175,Q96EK5,Q15555,O00584,Q9Y619,Q9NZJ7,O75489,O95202,P03886,Q96N66,Q13501,Q9H936,Q9BW92,Q9UHX1,Q9HC07,Q10713,P10253,P53701,O43681,Q9NVI7,Q05639,Q9UNW9 66 +Abnormal upper limb bone morphology 0.2407293847120395 0.0943547159220768 0.924827386717924 1.0 0.995028109414908 107 Q9NX62,P48651,P16278,P31749,P53634,P16435,Q14739,Q8WVQ1,P51798,Q08J23,Q32P28,Q8N3R9,Q7LGA3,Q9Y4P3,O75844,P08236,P98175,O95202,Q9UHX1,Q7RTS9 20 +Abnormal meningeal morphology 0.2770213768844134 0.0883409307948177 0.9296057080343288 1.0 0.9997929780706312 23 Q9UHX1,Q9H9S5,Q10713 3 +Abnormal cns myelination 0.2428122698956893 0.0879951353618785 0.929880542564284 1.0 0.9998577025079488 136 Q9Y5Y5,P51648,O00584,Q15067,Q9NZJ7,P03886,Q96CU9,P10253,P07602,Q7LGA3,Q9H9P8,O95831,P51572,O43676,P40855,O75306,Q86Y39,P35637 18 +Nonprogressive 0.3341215784163892 0.0854184156129526 0.9319287531259112 1.0 1.0 7 Q10713 1 +Talipes valgus 0.3136848341232185 0.0852908923843946 0.9320301319740312 1.0 1.0 5 Q9H2M9,Q15233,Q9HD42,O00754 4 +Pneumonia 0.2561405337950646 0.0833895013459212 0.933541836149088 1.0 1.0 54 P00813,Q13510,P04062,Q71SY5,P16278,O60220 6 +Focal emotional seizure 0.3222947401213802 0.0833266793923152 0.9335917869707016 1.0 1.0 9 Q05639 1 +Central adrenal insufficiency 0.3377777777777813 0.0831505368422401 0.93373184235184 1.0 1.0 6 P35222,Q9NSE4,O00170,Q9NRG9,O00255 5 +Rickets 0.3278978748775204 0.0823823209686167 0.9343426940813452 1.0 1.0 8 Q9NSD9 1 +Excessive salivation 0.275027276159138 0.0814187001352567 0.9351089779240656 1.0 1.0 28 Q05086,Q9NR77,P55795,P01889,P15586,Q15233,Q8TAB3 7 +Soft skin 0.3265847262345427 0.0784750690139379 0.9374501610968968 1.0 1.0 8 Q9NWM8 1 +Abnormal circulating aromatic amino acid concentration 0.3109271590544704 0.0779133259329731 0.937896999074229 1.0 1.0 5 P61457,Q9NVS9 2 +Immunodeficiency 0.2514110583519769 0.0740662886213777 0.9409576393406248 1.0 1.0 61 P09601,P00813,P14174,O95202 4 +Leiomyosarcoma 0.319038201026909 0.0730370336337378 0.9417766476147852 1.0 1.0 9 P31749,P25054,Q07812 3 +Astrocytoma 0.3052888189172306 0.072622720727645 0.9421063459316116 1.0 1.0 11 P48735 1 +Abnormality of the musculature of the limbs 0.2437432027087867 0.072595603735932 0.9421279252016624 1.0 1.0 168 P07196,Q15125,O15269,Q9H9S5,P00846,Q13510,Q99720,P31749,Q9NR77,P36551,Q9BQT8,Q14739,Q969X5,P07602,P50402,Q9Y487,O60313,Q15067,O75298,Q96BR5,P31483,Q9NZJ7,Q13501,Q9BW92,Q05639,O14979,Q7RTS9 27 +Abnormality of the plantar skin of foot 0.264328813889929 0.0717636241632301 0.9427900218626192 1.0 1.0 46 P31749,P16615,O95721,P53634,P61978,P09493,P07858,P42167,P22413,Q9Y487 10 +Increased urine alpha ketoglutarate concentration 0.3073748592972877 0.0686678143256823 0.9452540381560304 1.0 1.0 5 P21912,P09622 2 +Abnormality of circulating glucocorticoid level 0.2972443556366705 0.0682724301181972 0.945568770485978 1.0 1.0 14 P31749,Q13423 2 +Sleep wake cycle disturbance 0.3068720379146874 0.0673827038140476 0.9462770382479746 1.0 1.0 5 Q9UBM7,Q8N3U4,Q05086,Q9Y4R8 4 +Multifocal seizures 0.3068720379146846 0.0673827038140403 0.9462770382479804 1.0 1.0 5 Q9HA77,Q10471,Q96S52,Q9UGM6 4 +Spinal rigidity 0.3019568469962781 0.0672336732570261 0.946395678380624 1.0 1.0 12 Q9BTV4,P06753,Q8WXH0,P50402,Q13642 5 +Easy fatigability 0.2734732900432528 0.0669613745244941 0.94661245281726 1.0 1.0 23 Q9NWM8,P12235,O75340,P61978,Q53H12,P06753,P21912,O00170 8 +Bone fracture 0.3273741557201139 0.0668512676326733 0.9467001089920136 1.0 1.0 7 Q13501,P51798 2 +Fasting hyperinsulinemia 0.3065758293838748 0.0666283983275527 0.9468775373777034 1.0 1.0 5 O00255,P02545,Q16836,P00367 4 +Thick eyebrow 0.2597424371534813 0.0661367967144458 0.947268915427342 1.0 1.0 50 Q08J23,Q96D09,P04066,P15586,Q9UHX1,O95831,P08236,P98175 8 +Horizontal eyebrow 0.3165999813407425 0.0655041159945827 0.947772629286664 1.0 1.0 9 Q8N201,P00533,P78536,Q9NZN8 4 +Gonadal neoplasm 0.2730741240129013 0.0650981217548813 0.94809587588492 1.0 1.0 27 Q13423,Q01844,O75874,P48735 4 +Abnormality of the gingiva 0.2595625425852116 0.0644639156338515 0.9486008384783466 1.0 1.0 50 Q14108,P53634,P04062,Q14739,O75845,Q9Y4P3,P08236,P16278,Q15392 9 +Myopia 0.2402100544607514 0.0638939677773973 0.9490546554825467 1.0 1.0 113 P51648,P61978,Q9H9S5,Q9NWM8,P31749,Q8WVQ1,Q9Y487,Q08J23,Q15067,Q8NCH0,Q9Y4P3,O60220,P98175,Q15555,O15460,Q9UHX1,P22413,O43292,Q9NVI7 19 +Calvarial skull defect 0.3208216298108403 0.0617984106200495 0.950723369211716 1.0 1.0 8 O95202 1 +Craniofacial hyperostosis 0.3288138522886748 0.0603744923482879 0.9518573737460508 1.0 1.0 6 P31749 1 +Abnormality of the upper arm 0.2721782633223499 0.0592883783850202 0.9527224175374892 1.0 1.0 23 O14979,P16435,P48651,P50402,Q7RTS9 5 +Vertical supranuclear gaze palsy 0.2997040240186929 0.0589675446361261 0.9529779587397436 1.0 1.0 12 O15118,P61916 2 +Portal fibrosis 0.2780574474385477 0.0551860778899307 0.9559902202674452 1.0 1.0 4 P28288,P06737,P55263 3 +Exercise induced muscle cramps 0.3263212426309185 0.0543361208509636 0.956667371770758 1.0 1.0 6 P53985,P13473 2 +Abnormal pattern of respiration 0.2439445545594563 0.0526950437612854 0.957974888046609 1.0 1.0 192 P61978,Q96CU9,P01889,Q9H9S5,P00846,Q68CQ7,O75306,Q13510,P35637,O75880,Q969X5,P07602,Q86Y39,O60313,P51571,Q92804,P04062,Q8WXW3,O95831,O75844,Q9NSD9,O43464,Q96A33,Q15165,P98175,Q9Y619,Q9NZJ7,O75489,Q13501,P03886,P22695,Q9UHX1,P10253,Q10713,P22413,P06280 36 +Cystic hygroma 0.3172346405366046 0.0518107830144516 0.9586794634896872 1.0 1.0 8 P61978 1 +Abnormal anterior eye segment morphology 0.2424868221342026 0.0507067482078372 0.9595591992766 1.0 1.0 328 P10619,P51648,Q15125,P01889,Q9H9S5,P40855,Q13510,P16278,P00403,Q9NWM8,P31749,P22626,Q9NR77,Q14739,Q96DF8,Q8WVQ1,Q9Y297,O43505,Q15800,Q9NZ08,Q9Y287,Q9Y5Y5,O60313,Q08J23,P04062,Q8N3R9,Q8NCH0,Q86YV9,P08670,Q8WXW3,Q7LGA3,Q16625,Q9Y4P3,O75844,Q71SY5,Q9BUB7,P08236,O43464,Q8N2K0,Q96EK5,O95202,P03886,P04066,O75845,Q9UHX1,Q10713,Q9H6K4,Q9NVI7,O14979,O75381,P06280 51 +Abnormal platelet aggregation 0.2758892196584869 0.0499016031363223 0.9602007997790112 1.0 1.0 4 Q86YV9 1 +Moderate global developmental delay 0.3053200083919235 0.0494863108855041 0.9605317461651112 1.0 1.0 10 Q9BUB7,O43175,O95831 3 +Abnormality of thalamus morphology 0.2734518798940331 0.0486692569577368 0.96118287622362 1.0 1.0 19 O75306,Q9H9S5,P31749 3 +Abnormal tricuspid valve morphology 0.2946599270455557 0.0480437680157758 0.9616813610278624 1.0 1.0 13 O00192,Q9NX14,P53701,P54198,Q15233,O60826 6 +Prominent metopic ridge 0.2943269387103894 0.0468025046877624 0.9626706327708088 1.0 1.0 13 O75845 1 +Overriding aorta 0.3084700529215849 0.0414629614616989 0.9669268199186588 1.0 1.0 9 P53701,Q9Y4P3 2 +Ambiguous genitalia 0.2685473532961077 0.0411305910948687 0.9671917870646144 1.0 1.0 22 P16435,Q9NX14,O75845,P53701,O43175,P51809,Q8NCM8,Q15392 8 +Bulbous nose 0.2557460541760868 0.0400276583940161 0.9680710757484814 1.0 1.0 51 O00192,P16435,Q96DF8,P42892,Q9Y2B2,Q14696,O75845,O00571,P54198,Q8N201,P23786,P38159,Q96A33,Q96EK5 14 +Optic disc hypoplasia 0.3194523760358918 0.0383676114662233 0.96939458426451 1.0 1.0 6 Q9H3H1,O95721 2 +Skin tags 0.2679270474305848 0.0376642592956056 0.9699553727153414 1.0 1.0 22 O95202 1 +Hypopigmentation of the skin 0.2505639983328862 0.0358284789310311 0.9714191247371876 1.0 1.0 56 P31749,Q05086,P53634,Q9NZJ7,Q15125,Q86YV9,P53701,P07602,Q8IZA0 9 +Abnormal male reproductive system physiology 0.2617670901839985 0.0330335816487401 0.9736478079638466 1.0 1.0 38 P31749,P16435,O75298,P04062,P22307,O76024,P07686,Q9Y4P3,Q13423,P51809,O00170,P20700,O43464,Q969G3 14 +Abnormal labia minora morphology 0.3049599479365671 0.0316024090288038 0.9747891222236772 1.0 1.0 9 Q9Y619 1 +Abnormality of fibula morphology 0.2916629352929918 0.0307114290949507 0.9754996763631822 1.0 1.0 12 Q96HY6,Q9NR45,Q8WVQ1,P16435 4 +Metaphyseal irregularity 0.2914250402027248 0.0299056512492601 0.9761422988215852 1.0 1.0 12 Q7RTS9 1 +Abnormal mitochondrial shape 0.2888581176443097 0.0252384384629625 0.9798647772525756 1.0 1.0 5 Q9GZY8,Q7Z406 2 +Abnormal circulating glutamine family amino acid concentration 0.3015505575109726 0.0223283503979435 0.9821860341692252 1.0 1.0 9 O95298,P20674,Q9NVS9,Q9P0J1,Q9UJS0 5 +Absent toe 0.2663005989646472 0.0214264222632858 0.9829054964833008 1.0 1.0 27 Q9UHX1,O95202,Q7LGA3 3 +Focal non motor seizure 0.2954471201663065 0.0198075927901178 0.9841968609020452 1.0 1.0 10 Q05639 1 +Localized skin lesion 0.241928343604383 0.0194890665190353 0.9844509590419792 1.0 1.0 230 Q96PU5,P61978,Q15125,P01889,P48651,O15269,O75874,Q13510,P35637,P16615,Q9NWM8,P31749,P36551,Q14739,Q969X5,P07602,Q14574,P48735,Q8IZA0,Q9NZ08,Q08J23,P04062,P38435,P98194,Q8N3R9,Q8NCH0,Q7LGA3,Q9Y4P3,O75844,Q71SY5,Q15392,Q15555,Q92542,Q9Y619,Q9NZJ7,O15460,O95202,Q9UHX1,P53701,P22413,P06280 41 +Inflammation of the large intestine 0.2890649162738664 0.0185802577511194 0.9851759521506208 1.0 1.0 11 P08183 1 +Spinal canal stenosis 0.2949051021936666 0.0182564355397102 0.9854342810715352 1.0 1.0 10 P31749,Q8IWS0,P22413,Q9NSE4,O00170 5 +Stereotypy 0.2393354111581568 0.0180528855995319 0.985596663663693 1.0 1.0 76 Q15907,Q08J23,O95202,Q96N66,P55795,Q13501,Q01105,Q9UHX1,P61916,Q2M389,Q71SY5,Q05639,Q9UNW9 13 +Horseshoe kidney 0.2588090613630264 0.0177021309148609 0.9858764806907114 1.0 1.0 45 P16435,Q8NCH0,O75845,Q9UHX1,P98175 5 +Abnormal vitreous humor morphology 0.3023183918106148 0.0135677122308549 0.989174864006855 1.0 1.0 8 P53701,P04439 2 +Radioulnar synostosis 0.2635068699739422 0.0134611689209292 0.9892598655061656 1.0 1.0 22 O95202,Q8WVQ1,P16435 3 +Abnormal scapula morphology 0.24812795316467 0.011967658728615 0.9904514178044086 1.0 1.0 56 P07196,O60313,P16435,Q9Y619,Q14739,P50402,Q7RTS9,Q9Y487 8 +Cranial hyperostosis 0.2859450040769454 0.0118328656509682 0.9905589595047894 1.0 1.0 12 P31749,P22626 2 +Abnormal morphology of myocardial trabeculae 0.2822867298578158 0.0117585446665942 0.9906182549454638 1.0 1.0 5 Q15233,P35609,Q99797,P31040 4 +Recurrent skin infections 0.2843850854044262 0.0113781991607141 0.9909217064448316 1.0 1.0 13 Q8NCH0,P53634 2 +Aortic regurgitation 0.2639061607920008 0.009225569232074 0.992639165160084 1.0 1.0 24 Q9UHX1,Q9NZ08,P01889,O75844 4 +Hepatic fibrosis 0.2611790154087973 0.0091579328288927 0.9926931289222192 1.0 1.0 30 Q13510,P04062 2 +Dysgraphia 0.2765135796812382 0.0086100279523193 0.9931302765072574 1.0 1.0 16 Q13501,Q9Y4P3,P05067 3 +Agenesis of permanent teeth 0.2565303549052433 0.0081919294717811 0.9934638590556018 1.0 1.0 4 Q14696 1 +Abnormality of skin physiology 0.2310553163469396 0.0031906958682874 0.9974541973480844 1.0 1.0 97 P00813,Q13277,P16615,Q92542,Q08J23,Q14739,P22830,Q15125,P07858,P01889,P10321,Q8NCH0,P22413,Q15800,Q96A33,Q9NZ08,P14174 17 +Neoplasm of fatty tissue 0.2835109099223689 0.0018817050779184 0.998498617456364 1.0 1.0 11 P31749,P25054,P22413 3 +Papilloma 0.2885109789870244 0.0005795205154865 0.9995376095539066 1.0 1.0 10 P31749,P16615 2 +Hypoplasia of the frontal lobes 0.2829886454786754 0.0003597541474973 0.9997129577262188 1.0 1.0 11 Q15058,O60762,Q86XL3 3 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7721f336eca5c208c181deb9877426ee0efe479c --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating aldosterone", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal coccyx morphology", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal energy expenditure", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger flexion creases", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal perifollicular morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pulse", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rapid eye movement sleep", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 2nd finger", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the 2nd finger", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal interphalangeal creases", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent phalangeal crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical adenoma", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal fissure", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 2nd finger", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanges of the toes", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the 2nd finger", "Aplasia hypoplasia of the phalanges of the hallux", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonate wasting renal tubular acidosis", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bicoronal synostosis", "Bifid epiglottis", "Bifid nasal tip", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blind vagina", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac rhabdomyoma", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cephalohematoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 2nd finger", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Compensatory head posture", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical incisor", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crossed fused renal ectopia", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dacryocystitis", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased csf homovanillic acid", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Decreased vigilance", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duodenal ulcer", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalomalacia", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged interphalangeal joints", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Facial tics", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal clonic seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal hemiclonic seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked horizontal nystagmus", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glandular hypospadias", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucagonoma", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematochezia", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hypergastrinemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urinary potassium", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Insulinoma", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Intestinal atresia", "Intestinal bleeding", "Intestinal carcinoid", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular iliac crest", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large cafe au lait macules with irregular margins", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limbal dermoid", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited neck range of motion", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low serum calcitriol", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Moderately short stature", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple epiphyseal dysplasia", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thymus", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non convulsive status epilepticus without coma", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncommunicating hydrocephalus", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Oxycephaly", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Palate fistula", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic calcification", "Pancreatic cysts", "Pancreatic endocrine tumor", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell adenoma", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid hyperplasia", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Peg shaped maxillary lateral incisors", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Penoscrotal hypospadias", "Peptic ulcer", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Perineal fistula", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Photosensitive myoclonic seizure", "Photosensitive tonic clonic seizure", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent coccyx", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent spontaneous abortion", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Reflex seizure", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal angiomyolipoma", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal sodium wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal nonattachment", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rhizomelic arm shortening", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Sex reversal", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short middle phalanx of the 2nd finger", "Short middle phalanx of toe", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue neoplasm", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Stapes ankylosis", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Status epilepticus without prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous lipoma", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thrombophlebitis", "Thymus hyperplasia", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth abscess", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Underfolded helix", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral cleft lip", "Unilateral cleft palate", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Wide pubic symphysis", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABAT", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP9", "AKT1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG2", "AMPD2", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANXA11", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APOL2", "APP", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6IP1", "ARVCF", "ASAH1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATP11C", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATPAF2", "ATRX", "ATXN10", "B4GAT1", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCOR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRCA1", "BRD4", "BTRC", "BUB1B", "BUB3", "BUD23", "C19orf70", "C1QBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CAPN1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBX2", "CCDC22", "CCDC47", "CCDC8", "CCT5", "CD109", "CD2AP", "CD3EAP", "CDC40", "CDC42", "CDC45", "CDC6", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CDK6", "CELF2", "CEP135", "CEP250", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHMP4B", "CHORDC1", "CHP1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "CNP", "COA3", "COA7", "COG7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COQ8B", "COQ9", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CREB1", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSB", "CTSC", "CUL3", "CUL4B", "CUL7", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DAXX", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DNAAF5", "DNAJC13", "DNAJC21", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGFR", "EHHADH", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "ENPP1", "EPB41", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC9", "EYA4", "EZH2", "EZR", "FAH", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GDAP1", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNAI2", "GNAI3", "GNE", "GNPAT", "GNS", "GOT2", "GPAA1", "GPD2", "GPHN", "GPI", "GPKOW", "GPRASP2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HAX1", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIRA", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOXD13", "HPRT1", "HPS3", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IGF2R", "IGHMBP2", "IMPAD1", "INF2", "INTS1", "IRF2BPL", "IRS4", "ISCU", "ITCH", "ITM2B", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIAA0319L", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF7", "KIFBP", "KLC2", "KMT2A", "L2HGDH", "LAMB1", "LAMC1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LEMD2", "LEMD3", "LETM1", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRSAM1", "LSS", "LUZP1", "LZTFL1", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAPK1", "MAPRE2", "MARK3", "MARS", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED12", "MED17", "MED23", "MED25", "MEN1", "MESD", "MFF", "MGME1", "MIA3", "MICU1", "MIF", "MINPP1", "MIPEP", "MMAB", "MOGS", "MORC2", "MPDZ", "MPG", "MPI", "MPP5", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTHFS", "MTM1", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MYH14", "MYH9", "MYO1E", "MYO6", "NAA10", "NAA15", "NACC1", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPH", "NCDN", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NELFA", "NEMF", "NEU1", "NF2", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP56", "NOVA2", "NPC1", "NPC2", "NPM1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCDH19", "PCK2", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDP1", "PDSS2", "PDXK", "PEPD", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PISD", "PITRM1", "PKN1", "PKP2", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POMGNT2", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PREPL", "PRKACA", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QRICH1", "QRSL1", "RAB11B", "RAB18", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "RECQL4", "REPS1", "RFC1", "RFC2", "RFT1", "RHOA", "RINT1", "RNASEH2A", "RNASET2", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS29", "RPS6KA3", "RPS7", "RPSA", "RREB1", "RTN2", "RTN4IP1", "SAMHD1", "SAR1B", "SARS", "SARS2", "SASS6", "SATB2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEPT9", "SERAC1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIN3B", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC5A6", "SLMAP", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMG8", "SMG9", "SMN1*", "SMPD4", "SNAP29", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD7", "STAT1", "STK4", "STT3A", "STT3B", "STUB1", "STX3", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL2", "TCF20", "TCOF1", "TDP2", "TECR", "TELO2", "TENM3", "TERF2IP", "TFAM", "TFG", "TFRC", "THG1L", "THOC2", "THOC6", "TIA1", "TIMM50", "TIMM8A", "TIMMDC1", "TJP2", "TKT", "TMCO1", "TMEM126A", "TMEM165", "TMEM199", "TMEM38B", "TMEM43", "TMEM70", "TMLHE", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOP3A", "TOR1A", "TOR1AIP1", "TP53", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMU", "TRRAP", "TSC2", "TSFM", "TSPYL1", "TSR2", "TTC19", "TTC21B", "TTC37", "TTC5", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWNK", "UBA1", "UBA5", "UBE3A", "UBE4A", "UBE4B", "UBTF", "UFD1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC45A", "UPF3B", "UQCC2", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP7", "USP9X", "VAMP7", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VPS13A", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WBP11", "WDR1", "WDR11", "WDR26", "WDR36", "WDR45B", "WDR73", "WFS1", "WNK1", "WRAP53", "XPNPEP3", "XRCC1", "YARS", "YARS2", "YEATS2", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZNF687", "ZPR1"], "leading_proteins": ["AAAS", "AARS2", "ABCB1", "ABCD3", "ABHD12", "ACAT2", "ACBD5", "ACOX1", "ACP2", "ACTN2", "ADA", "ADAM17", "ADK", "AFG3L2", "AGK", "AGPS", "AIFM1", "AIP", "AK2", "AKAP9", "AKT1", "AKT2", "ALDH18A1", "ALDH3A2", "ALDH6A1", "ALG1", "ALG11", "ALG2", "ANKLE2", "ANXA11", "APC", "APOL2", "APP", "ARL6IP1", "ARVCF", "ASAH1", "ASNA1", "ATAD1", "ATAD3A", "ATP1A1", "ATP2A2", "ATP2C1", "ATP6", "ATP6V0A2", "ATPAF2", "ATXN10", "B4GAT1", "BAX", "BCAP31", "BCS1L", "BICD2", "BTRC", "C19orf70", "CALM3", "CANT1", "CARS2", "CASK", "CCDC22", "CCDC47", "CD109", "CEP135", "CEP250", "CERS1", "CHEK2", "CHMP1A", "CHMP2B", 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0.3373638196000335 3.045697762577092 2.514285464673758 1.2272389207362138 0.3056726473181033 0.4989860015810922 0.2295798469686227 0.4103737017227389 0.3757594500595086 0.0150905845261323 +Peroxisome 14 38 2.3950437148277395 0.0166183838188076 8.944174757281553 33.31553398058252 0.1912181674752777 0.455069334940637 4.249990296795741 4.279943228040891 1.217274798105213 0.3271299230574079 0.0001556448139746 0.2695684389372801 0.0251363642152908 0.000923573561466 0.0002655559882184 +Glycosaminoglycan degradation 6 7 2.1732246602875738 0.0297634126220047 3.407766990291262 5.864077669902913 0.1350713234786387 0.1703873780123549 1.3379225542760151 0.7043353086258667 1.932540087143412 0.2532951180616937 0.005175564892058 1.0 0.1105474823156849 0.0025975272437437 0.0001590313802548 +Steroid biosynthesis 5 12 2.1711213074729296 0.0299220037749994 4.451456310679611 10.919902912621358 0.8535439655720318 0.1867209176898754 2.1463612955879627 1.3314318120676296 1.5430058140543457 0.1933818217769055 0.0081813130820843 0.0652597674910206 0.1277572387780678 0.0041470760753771 2.763867591720716e-05 +Other glycan degradation 4 8 2.1072579188714124 0.0350952288746757 3.966019417475728 7.12378640776699 0.0449593300314452 0.158186848086018 1.7909726921672984 0.8075596903062239 1.9584092358200416 0.2320333335657103 0.0006915935551566 1.0 0.1277572387780678 0.0002735626391213 0.0003706302782608 +Antigen processing and presentation 11 20 2.0063226672265664 0.044821833134057 5.337378640776699 16.74757281553398 0.2387870946403815 0.5680791453500826 2.8523982282892524 1.5499354612429144 0.9338462051385796 0.3189030666688743 0.705435493329119 1.0 1.0 0.6149168035506691 0.1196653936274396 +Nicotinate and nicotinamide metabolism 4 7 1.975756598955082 0.0481823511558334 1.577669902912621 5.555825242718447 0.8765246600520394 0.3422223651000359 1.128314495064996 0.9700815942780172 0.9601213388242128 0.2885413402242885 0.009996551282915 1.0 1.0 0.0050923434600555 0.0005338561483377 +Hypertrophic cardiomyopathy hcm 5 9 1.965410071878692 0.0493667947006908 3.429611650485437 9.101941747572816 0.6486134300733651 0.4298239576137608 1.8675556020784376 1.719193792909202 1.0005513529453438 0.3180395638112931 0.3726668046175335 1.0 1.0 1.0 0.612992755958387 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3cf9fec918b8a058cb7238731c428fc2d3516bcf --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 179, + "title": "Average number of proteins per term", + "value": 17.58659217877095 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5f4f25c9f7ef04d253f4be800b305db0e9396e5b --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": 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P14406,Q9UDW1,P20674,P00846,O75438,O43676,P06576,O75306,P09669,O75964,P00403,Q86Y39,Q9Y487,O95298,P13073,P24539,Q93050,O14949,P61421,P36542,O75489,P03886,P22695,P15954,P10606,P56134 26 +Parkinsons disease 0.5682129573096004 3.5365800501146736 0.0004053436395179 0.0700004908297486 0.0080618346081901 58 P14406,Q9UDW1,P21796,P20674,P00846,O75438,O43676,P06576,O75306,P09669,P00403,P12236,P45880,Q9Y277,O95168,P60604,O95298,P13073,P14927,P24539,O43464,O14949,P12235,P36542,O75489,P03886,P22695,P15954,P10606,O14548 30 +Cardiac muscle contraction 0.7107280013122593 3.240282008775303 0.0011941153715855 0.1925501832697534 0.016442050116447 22 P16615,P13073,O14548,P05023,P09493,P14927,P05026,Q9UDW1,P14406,P20674,P22695,P15954,P10606,P54709,P09669,P67936,O14949,P00403 18 +Huntingtons disease 0.4830484838186123 3.153568624109258 0.0016128730259585 0.2509408629861995 0.0180440169779116 81 P14406,Q9UDW1,O43674,P21796,P20674,P00846,O75438,O43676,P06576,O75306,P09669,P00403,P45880,P12236,Q9Y277,P21912,O95168,P09496,Q9UJW0,O95298,P13073,P14927,P24539,Q07812,P19388,O14949,P12235,P36542,O75489,P22695,P16220,P15954,P10606,O14548 34 +Steroid hormone biosynthesis 0.7682746374667088 3.0632799661652585 0.0021892513686827 0.3245023358987351 0.0230515291173066 2 Q53GQ0 1 +Alpha linolenic acid metabolism 0.823040578715599 2.9976416447939584 0.0027207739117187 0.3859520552964792 0.027056585010981 3 O15254 1 +Alzheimers disease 0.4836497592798267 2.955879004400244 0.0031177937465514 0.428194791552633 0.0280770867551577 66 P14406,Q9UDW1,P20674,P00846,O75438,O43676,P06576,O75306,P09669,P00403,P16615,P05067,O95168,P0DP25,O95298,P13073,P14927,P24539,O14949,P36542,Q92542,O75489,P22695,P49841,P15954,P10606,P78536,O14548,P27361 29 +Vibrio cholerae infection 0.6719380038767571 2.95397396850112 0.0031371046653807 0.4301740918883066 0.0280770867551577 21 O43731,P24390,Q9Y487 3 +Snare interactions in vesicular transport 0.7452451005967232 2.899460041977272 0.0037380598712715 0.4884788952553843 0.0303361945545012 16 Q9P2W9,Q13277,O95721,O15400,O15498,Q13190,O60499,O95249,Q12981,O43752 10 +Glycosphingolipid biosynthesis ganglio series 0.7975133214920014 2.8728849009784176 0.0040674227335641 0.5178757307608521 0.0303361945545012 3 P16278,P06865 2 +Glycosphingolipid biosynthesis globo series 0.7975133214919969 2.8728849009784003 0.0040674227335644 0.5178757307608713 0.0303361945545012 3 P06865,P06280 2 +Sphingolipid metabolism 0.7841381459692491 2.8255100518176213 0.0047205406864507 0.5712912329056831 0.0337990713149876 13 O95470,Q13510,P04062,O15269,O43681,Q16739,P16278,P06280 8 +Primary bile acid biosynthesis 0.6936963598697881 2.6654055410937914 0.0076895530528551 0.7488611608385123 0.0529396152485025 2 P22307 1 +Porphyrin and chlorophyll metabolism 0.7277861961151318 2.5217374546160234 0.0116776830011013 0.8778622869574081 0.077418713229524 13 P36551,P09601,P22830,P30519,P53701,P08236 6 +Glycerophospholipid metabolism 0.6613970122557351 2.406097534537702 0.0161239592717836 0.9455084855488848 0.097614511180235 16 Q9UG56,P35790,Q9BVG9,Q96N66,Q9HCL2,Q9HBU6,P48651,Q86UL3,O95674,Q92604,P43304 11 +Peroxisome 0.5161943143770789 2.3950437148277395 0.0166183838188076 0.9501972601494793 0.097614511180235 38 Q9Y5Y5,Q9NR77,Q15067,Q9BQG2,O43808,O14734,O15254,O00116,Q13011,O75874,P40855,P48735,Q9UKU0,O75381 14 +O glycan biosynthesis 0.7263843648208406 2.217513477988969 0.0265880230717407 0.99196276420416 0.1442198827224728 4 O43505,Q10471,Q10472 3 +Glycosaminoglycan degradation 0.7892708950800245 2.1732246602875738 0.0297634126220047 0.995521846825133 0.1487788521034693 7 P07686,P15586,P06865,P08236,P16278,P54802 6 +Steroid biosynthesis 0.6783560674694088 2.1711213074729296 0.0299220037749994 0.995650983713922 0.1487788521034693 12 Q15125,Q16850,Q15800,Q15392,Q14534 5 +Other glycan degradation 0.7521811181338384 2.1072579188714124 0.0350952288746757 0.9983299970496692 0.1532206333796819 8 Q9BTY2,P06865,P04066,P04062 4 +Graft versus host disease 0.6888522238963403 2.0298677562231213 0.0423699833791693 0.9995690793277144 0.1685383783304734 4 P10321,P01889 2 +Allograft rejection 0.6888522238963403 2.0298677562231213 0.0423699833791693 0.9995690793277144 0.1685383783304734 4 P10321,P01889 2 +Autoimmune thyroid disease 0.6888522238963403 2.0298677562231213 0.0423699833791693 0.9995690793277144 0.1685383783304734 4 P10321,P01889 2 +Antigen processing and presentation 0.5381181092484772 2.0063226672265664 0.044821833134057 0.9997276638690944 0.1744153941520916 20 Q03518,P27824,P04439,P07858,Q99538,P01889,P10321,Q9UL46,P16220,P61289,P0DMV9 11 +Nicotinate and nicotinamide metabolism 0.746982323505789 1.975756598955082 0.0481823511558334 0.9998550821617171 0.1767331250284732 7 P43490,P22413,Q9BQG2,Q13423 4 +Hypertrophic cardiomyopathy hcm 0.7005797266422523 1.965410071878692 0.0493667947006908 0.9998840359386004 0.1767331250284732 9 P16615,P09493,P54619,P50402,P67936 5 +N glycan biosynthesis 0.5439200750441175 1.940040572125101 0.0523747593308776 0.999934241034819 0.1838251356907274 19 Q96AA3,O60762,Q8TCJ2,P46977,Q86YN1,P33908,O60476,Q9BT22,P04843,Q2TAA5 10 +Renin angiotensin system 0.6682148034681252 1.9250675440995144 0.0542209087046108 0.9999536171049948 0.1866450511177949 4 P10619 1 +Calcium signaling pathway 0.5624861558309665 1.8730939315356945 0.0610554152083093 0.9999873365185088 0.2023873948571736 17 P16615,P12236,P45880,P21796,Q9Y277,P0DP25 6 +Aldosterone regulated sodium reabsorption 0.6990809368514802 1.8473055450755484 0.0647028697558738 0.9999936907356544 0.2104194512161975 8 P05023,Q96PU5,Q9Y3B8,P05026,O14654,P54709,P27361 7 +Amyotrophic lateral sclerosis als 0.6070603716632821 1.833270148525556 0.0667624063867218 0.9999957478526704 0.2104194512161975 13 P07196,P07197,P20339,Q9BUN8,Q07812 5 +Riboflavin metabolism 0.7166586661528562 1.8316399771491008 0.067005076644264 0.9999959412599476 0.2104194512161975 7 Q9NPH0,P11117 2 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.6847995838815469 1.7920795192159849 0.0731202291001089 0.9999987491959412 0.218142016815325 5 O43292 1 +Dilated cardiomyopathy 0.670084479697793 1.702523103779588 0.0886573512264823 0.9999999393231034 0.251899458246672 8 P09493,P50402,P67936 3 +Cell adhesion molecules cams 0.5705506866938365 1.6152129117725225 0.1062645953727259 0.9999999981532662 0.2882024632078476 13 P04439,P10321,P01889,Q92896,Q16625,P10586 6 +Pantothenate and coa biosynthesis 0.5525412826919512 1.5727726013901584 0.1157714819679656 0.9999999997276994 0.3003347140908093 3 P22413 1 +Folate biosynthesis 0.5197458505365933 1.3857519658207882 0.1658226542961911 0.999999999999992 0.4066062345070988 3 P00374 1 +Biosynthesis of unsaturated fatty acids 0.5350703644058057 1.1845885770249824 0.2361801556454872 1.0 0.5192554199989662 10 Q53GQ0,O15254,O95864,Q15067 4 +Prostate cancer 0.4547411814747425 1.1394882313884027 0.2544995741006897 1.0 0.5415510497638187 17 P31749,P35222,P00533,P49841,P31751,P24941,P16220,P27361 8 +P53 signaling pathway 0.4828460129945578 1.1331265507083874 0.2571611130163385 1.0 0.5415510497638187 14 Q9Y3B8,Q07812,P24941,O14681 4 +Protein export 0.455541411589793 1.0769705739234805 0.2814934120041013 1.0 0.570123944539295 16 Q9Y5M8,P67812,Q99442,Q9UGP8,P61009,Q9UHB9 6 +Type i diabetes mellitus 0.5377660165279371 1.0556081070613708 0.2911472955075753 1.0 0.5790596210650665 5 P10321,P01889 2 +Hedgehog signaling pathway 0.5577128783531295 0.9820266240432844 0.3260867320096547 1.0 0.6060478251856641 6 Q9Y297,P49841,P98164 3 +Vasopressin regulated water reabsorption 0.4211303063213488 0.9732388778489612 0.3304345924892065 1.0 0.6060478251856641 18 Q15907,P51148,P61020,P20339,P16220,Q8NCM8,Q9UJW0 7 +Endometrial cancer 0.4281028574365184 0.7867016184437976 0.4314565564446431 1.0 0.735530700986582 14 P31749,P25054,P35222,P00533,P49841,P31751,P27361 7 +Apoptosis 0.3887363216600491 0.7420040806671695 0.4580848632012793 1.0 0.7592332454910091 18 P31749,P31751,Q07812,O95831,O94919 5 +Melanogenesis 0.4105739168756785 0.6009905103898447 0.5478463068647161 1.0 0.8478095056329897 12 O14641,P35222,P49841,P16220,P27361,P28482,P0DP25 7 +Basal cell carcinoma 0.4591336650174944 0.5248466088007115 0.5996898276581886 1.0 0.8798727799247194 6 P25054,O14641,P49841 3 +Proximal tubule bicarbonate reclamation 0.4360586683316421 0.5141958004405202 0.6071151035938793 1.0 0.8835252320593854 8 P05026,Q9UBX3,P05023 3 +Mtor signaling pathway 0.3620461482658984 0.4610822624907006 0.6447395869877446 1.0 0.8912660567883159 16 P31749,P49815,Q15382,P31751,P27361,P28482 6 +Ecm receptor interaction 0.4442431126821398 0.4605284128914952 0.645136982098109 1.0 0.8912660567883159 6 Q08722 1 +Progesterone mediated oocyte maturation 0.3248800788319514 0.4514877689223651 0.6516380383752316 1.0 0.8912660567883159 27 P31749,P30260,P31751,P24941,Q9UJX3,P06493 6 +Thyroid cancer 0.3888952971469734 0.3930744619346609 0.6942644855451277 1.0 0.92054328083391 10 Q16204,P35222,P06753,Q92734,P27361 5 +Phosphatidylinositol signaling system 0.3675596208065824 0.2922243712605283 0.7701150789101023 1.0 0.9482692913945254 10 Q10713,O95674,P0DP25 3 +Starch and sucrose metabolism 0.3433468892791296 0.2868749083539542 0.7742081035707675 1.0 0.9482692913945254 14 P10253,P22413,Q8NBZ7 3 +Colorectal cancer 0.3321170215637118 0.2822370918710925 0.7777617187120918 1.0 0.9482692913945254 16 P31749,P25054,P35222,P49841,P31751,Q07812,P27361 7 +Jak stat signaling pathway 0.3896314537157359 0.2726205841518371 0.785144887241161 1.0 0.9482692913945254 7 P31751 1 +Ppar signaling pathway 0.304368744880087 0.2652694105414441 0.7908019274725737 1.0 0.9482692913945254 21 O15254,Q9UKU0 2 +Melanoma 0.3589667329039365 0.2537463662601478 0.7996915109566403 1.0 0.9482692913945254 10 P31749,P00533,P27361,P31751 4 +Epithelial cell signaling in helicobacter pylori infection 0.3010104293818031 0.2519305376007891 0.8010947551018446 1.0 0.9482692913945254 25 Q9Y487 1 +Glioma 0.3177595514122506 0.178643152374569 0.8582179087830282 1.0 0.9688821784319492 15 P31749,P00533,P31751,P27361,P28482,P0DP25 6 +Dorso ventral axis formation 0.3411910636356355 0.1681280008905783 0.8664825813632466 1.0 0.9688821784319492 5 P00533,P27361 2 +Viral myocarditis 0.3377187909874503 0.1648483329219676 0.8690633602434681 1.0 0.9688821784319492 10 P10321,P01889 2 +B cell receptor signaling pathway 0.3186133592450745 0.1460774851536502 0.8838602199889418 1.0 0.9688821784319492 13 P31749,P49841,P31751 3 +Small cell lung cancer 0.3216507586058924 0.1456643180611511 0.8841863909205003 1.0 0.9688821784319492 12 P31751,P24941 2 +Acute myeloid leukemia 0.3399458722697835 0.1434897398067673 0.8859034138487603 1.0 0.9688821784319492 9 P31749,P31751 2 +Endocytosis 0.2518436415925954 0.0644539979280662 0.948608735240265 1.0 1.0 59 Q15907,Q9BRG1,O43633,P61020,Q96PU5,P10321,P01889,P46934,P20339,Q9H223,P09496 11 +Bladder cancer 0.3223592575609728 0.0450048373876644 0.9641034531851548 1.0 1.0 6 P00533,P27361 2 +Pancreatic cancer 0.2856198079134933 0.0228978044041773 0.981731791769262 1.0 1.0 14 P31749,P00533,P27361,P31751 4 +Galactose metabolism 0.2838069230596196 0.0050378484853015 0.9959803954767928 1.0 1.0 12 P10253,P06280 2 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3480e1edfb68af08e7478793cb34fe2fc69d9b2e --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM17", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEX1", "APP", "APRT", "AQR", "ARF6", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASNA1", "ASNS", "ATG4B", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCAT2", "BDH2", "BIRC6", "BLM", "BLVRA", "BNIP1", "BPNT1", "BRCA1", "BRD8", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "C1D", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CBL", "CBR1", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDS2", "CETN2", "CFL1", "CFL2", "CGN", "CHD8", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHORDC1", "CHP1", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT10", "CNOT2", "CNOT7", "CNOT9", "COMT", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CREB1", "CRKL", "CRNKL1", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBT", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH3", "DIS3", "DLAT", "DLD", "DLG1", "DLST", "DNM1L", "DNM2", "DNMT1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSC2", "DSG2", "DSP", "DTYMK", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", 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0.4047880585679882 2.6930013625985207 2.1985522104416564 1.0262193137091864 0.3353529084578252 0.002140052762423 0.0188245552589776 0.0088166073526355 0.0039562767661884 0.018870184963526 +Ion channel transport 12 30 2.5089520592998182 0.0121089917177339 9.031553398058252 27.74271844660194 0.8980727715308076 0.3472480807052641 4.2752930421976005 3.4432740668393595 1.4212023690700646 0.3452897078102002 0.1082551558867238 0.3274019772455256 0.0453414776018772 0.1360002203186876 0.1034454751370625 +Transport of inorganic cations anions and amino acids oligopeptides 4 11 2.504528334432788 0.0122614783749623 3.45873786407767 9.99514563106796 1.347451847228265 0.1988162564497566 2.1544143797408783 1.7967002462592632 1.0339867286779445 0.2465647399589519 0.0108972369658975 0.0188245552589776 0.0678620701894922 0.0039562767661884 0.0610180463767549 +Mitophagy 5 11 2.479099275972391 0.0131714639996658 3.662621359223301 11.783980582524272 1.3564301304992197 0.1917930287367771 1.8155907654273165 1.3363606860118669 1.2723890100166135 0.2636913304405313 0.0057593610144797 0.0001966568602221 0.0015498580582828 0.0193169154759243 0.0008169542553505 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 7 12 2.474620248321747 0.0133377912205949 4.016990291262136 10.99757281553398 1.1239772251284714 0.2752182956921286 1.9514004604865949 1.181365809872934 1.0815649178051203 0.2865915409883788 0.0002185846219627 0.0036723611473879 0.0143328298354406 0.000963248429344 1.393273560220496e-06 +Mitochondrial biogenesis 15 34 2.4459140195467297 0.0144485452288587 10.572815533980584 33.521844660194176 0.7125383902440768 0.3998427377933914 4.798567629623383 2.9315837025395943 1.2191838320541302 0.3355715376706868 0.0156202968480086 0.0627750690965546 0.1997425917545389 0.0543296939149059 0.0080072027585734 +Metabolism of lipids 47 198 2.351952536851775 0.0186751577130002 47.21601941747573 182.9902912621359 0.7669400545274999 0.4573741022352977 16.76057659641467 20.451455734561765 1.5920609507025254 0.4091924181498379 1.558633732877601e-05 0.0337835018646982 0.0003717503629102 1.3426177725033917e-05 5.47402049667068e-07 +Pink1 prkn mediated mitophagy 5 8 2.340151444997721 0.0192759216937128 3.2815533980582523 8.473300970873787 1.395617281862234 0.1554977461962819 1.6230588150315317 0.9738153254376878 1.3577427922485954 0.2414588001366878 0.0015284527669486 6.765318543664244e-05 0.0005470061355849 0.0073447144383531 0.0001004910149917 +Keratan sulfate keratin metabolism 4 5 2.3305656612346644 0.0197762739363425 3.1359223300970873 5.439320388349515 0.1148000450757159 0.1857420338858874 1.294488268568909 0.7592200419566036 1.8452752770630356 0.2520366769461069 0.0142767807743484 1.0 1.0 0.0621585272883563 0.0079370796506279 +Heparan sulfate heparin hs gag metabolism 4 5 2.288040412202525 0.0221351678105434 2.4320388349514563 4.83252427184466 0.8003221575390526 0.2230961855611341 1.2648123228701085 1.2708877857521428 1.4628061886044337 0.2633127679646707 0.2587598307380946 1.0 0.2685353106225043 0.1800390494619342 0.0678374957909117 +Rab geranylgeranylation 13 24 2.255402331339139 0.0241080865492886 7.703883495145631 20.33009708737864 0.0425571144344789 0.6104117024455028 4.535157640190479 2.923418498732157 0.9174138709438756 0.3132937075649342 0.0841493844269546 1.0 1.0 0.3757594500595086 0.1208874805839759 +Rhog gtpase cycle 10 37 2.248493508478872 0.0245447385656096 9.8373786407767 35.66504854368932 0.6614029400837433 0.4973720188279035 4.308521802053122 2.993429981792782 0.9950331841901028 0.3588671909523165 0.1748989247311522 0.290515894493261 0.5010041483550427 0.244978619195686 0.0071993249598634 +Vitamin d calciferol metabolism 2 5 2.246019607017347 0.0247027520517255 1.2160194174757282 3.1601941747572817 0.7445815680804749 0.3219454249036758 0.815169098909629 0.9129956885685208 1.3106248902727975 0.2921839998108322 0.0234121875355895 1.0 0.075113296023457 0.0147480216610697 0.0544194668097373 +Selective autophagy 5 31 2.244452344060478 0.0248033118748527 7.315533980582524 31.50728155339806 0.9304065525388932 0.4028226131520862 3.350474746292583 3.101431769008479 1.074438805028982 0.3502038092942861 0.0550370045311565 0.0040269256520789 0.0271898890726632 0.0780890051531907 0.0434273695437325 +Phospholipid metabolism 23 46 2.2037828117290603 0.0275396219446566 12.859223300970871 45.932038834951456 1.017004520648936 0.3949296504793965 6.241466981115118 7.362344677079641 1.3242274243570669 0.3709328103546776 0.2058008323724622 0.1723298875515411 0.1932789242336213 0.324161243023813 0.0405797644707419 +Cargo concentration in the er 8 15 2.191440305211362 0.0284199451084077 4.813106796116505 14.480582524271844 0.5034715777808771 0.4707340910089172 2.4168749497181627 1.7521447745979526 1.0073939692365603 0.3173017432503084 0.5133658415211507 1.0 0.2012104780589677 0.4301270919610729 0.0234644839392777 +Intra golgi and retrograde golgi to er traffic 17 103 2.1860568055731866 0.0288114496193332 23.762135922330096 91.83252427184466 0.7836914286379623 0.5449079285432085 8.961715947260837 10.213669235838784 1.1120768516172963 0.4008074869702365 0.0242334216830302 0.0559390979061329 0.0003654025734086 0.0044088473407 0.0030844872236142 +Heme biosynthesis 1 5 2.1640912456711434 0.0304573472521487 1.616504854368932 5.298543689320389 0.3799926448994593 0.4874403957378427 1.1838391624700522 0.9657723985293564 0.9261555255993276 0.2942490709743225 0.3131041734647267 0.0561990347849709 0.1105474823156849 0.2541534411772372 0.1129571724371578 +Formation of atp by chemiosmotic coupling 6 10 2.162344369382288 0.0305916421306382 3.5898058252427183 9.805825242718448 0.4783111855246443 0.2899716869602585 2.2195497140568734 0.9063771094889388 1.382334358445268 0.2713732710506487 0.0081813130820843 0.001984476440523 0.0078714328443906 0.0041470760753771 0.0037486095651754 +Class a 1 rhodopsin like receptors 3 7 2.1558279873457824 0.0310970992272197 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.0255113558567383 1.0 0.1854358412925483 0.0133829456596615 0.0171177319456962 +Peptide ligand binding receptors 3 7 2.1558279873457824 0.0310970992272197 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.0142767807743484 1.0 0.152955667850895 0.0073447144383531 0.0079370796506279 +Iron uptake and transport 3 18 2.133950865887095 0.0328468030490078 4.089805825242719 17.9126213592233 1.0360420001787272 0.323786301352462 2.0477771422769826 0.9863810102632052 1.0014322629164618 0.2971986354372174 0.0286114952840351 0.0142466262053111 0.0004791823223436 0.0128293519549119 0.1114244714574529 +Tp53 regulates metabolic genes 18 41 2.097357308096804 0.0359619572992422 9.567961165048544 35.47572815533981 0.101655991626129 0.675386172281155 4.509186170565808 3.1224046626849615 0.8223942836099251 0.3288916000544298 0.2593104159570634 0.3339036757647639 0.5608745977717441 0.1447695065926066 0.0511203946882603 +Gpcr ligand binding 3 10 2.084349854499043 0.037128355586685 3.4611650485436893 9.330097087378642 1.051447004644797 0.2131328881138611 1.5951828582954857 1.3192992367203638 1.3003237502897853 0.2397874119507845 0.1679315882748155 1.0 0.3622612502953293 0.0989248704147511 0.1838658218206393 +Cholesterol biosynthesis 7 17 2.0606242402174733 0.0393389023424051 5.878640776699029 16.75 1.3996798653689082 0.2350718901934974 2.503362805703168 1.8986773628384943 1.0886216368414 0.270950573691616 0.0057593610144797 0.1093006244161378 0.208984012191681 0.0024022577840735 1.092250734135325e-05 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 9 21 2.017142895889635 0.0436806032507721 6.014563106796117 17.274271844660195 0.870961683103299 0.329566970411291 2.8591161566949044 2.4465188670593117 1.2657234914365352 0.3108311955329007 0.0932925430126205 1.0 1.0 0.1524764865133537 0.2894589157522063 +Ion transport by p type atpases 7 11 1.979358110022249 0.0477757013233863 3.7305825242718447 10.33980582524272 0.407323607098393 0.3519804201795568 2.374569281431047 1.6883576098110384 1.2891970822622851 0.3108388098264688 0.6213525141686728 1.0 1.0 0.5315101420828222 0.4493239706483273 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a35f45a8d834521034ca5e9b8686309a262a0935 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 1396, + "title": "Average number of proteins per term", + "value": 20.249283667621775 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bd939f6cabcd571b0c3b0438ec5b7150cf170097 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..802df63789477b4bcc3e397033050cf1a981801d --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,382 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein localization 0.6151735324095766 4.591512874393484 4.400444915120261e-06 0.0061242047576296 0.001330703461725 81 O60830,P51648,Q9NS69,O14925,P49069,Q99595,Q5T8D3,Q13190,P21796,Q13011,O75874,P06576,P40855,Q8N4H5,Q9NX63,Q9NR77,P09601,Q13505,P05067,O15254,O43615,O00116,P50402,Q9Y5J7,Q9Y5J9,Q9Y5Y5,Q9Y5L4,Q9Y512,Q15067,O14734,Q3ZCQ8,O60220,P46379,O43808,O43681,Q10713,Q15388,O75381 38 +Transport of small molecules 0.4828398231189626 4.164405044670241 3.1216550856472125e-05 0.0426430659166553 0.0016760886536783 159 Q9UBV2,Q99623,P28074,P05023,Q9GZP9,Q96PU5,Q8TB61,P20618,P05026,O00231,Q9BPX6,P21796,P30519,P61289,P40855,P27105,P16615,Q70HW3,O15118,P45880,P12236,P09601,Q9UBX3,Q9C0H2,P35613,Q9Y289,P51798,Q9BUN8,Q9Y277,P61916,Q13438,P09496,Q9Y487,P53985,Q9NWR8,P63218,P98194,Q9BU23,Q9UL46,Q93050,Q9H0U3,P28288,Q8WTV0,Q96QD8,Q15758,P28072,P61421,P12235,Q99808,O95202,Q9Y6M7,Q8NE86,P30825,Q9HD20,P05198,Q9H936,O43242,Q9Y4W6,Q10713,P08183,P49721,Q8IYU8,Q8NEW0,P51790 64 +Sphingolipid metabolism 0.7620560902403785 3.8420977599689654 0.0001219872272721 0.156592088283762 0.0023651967954441 28 P10619,P51648,O95470,P27544,P17900,P04062,Q9NZJ7,O15269,P07602,Q96G23,Q16739,P06865,Q13510,P06280 14 +Proton coupled monocarboxylate transport 0.9047055341817112 3.743544752471296 0.000181442268087 0.2237777445111714 0.0032473513621729 2 P35613 1 +Noncanonical activation of notch3 0.8949393311630667 3.696723493273363 0.000218399993987 0.2628174248879237 0.0036295999000712 2 P67809 1 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.5385335347444716 3.6272530625074086 0.0002864525124208 0.3296430804534891 0.0042093442877846 68 P56385,Q9UDW1,P20674,P00846,O75438,O43676,P06576,O75306,P09669,O75964,P00403,O75880,Q8N183,Q9NX14,O95168,Q86Y39,O95298,P13073,Q9NPL8,P24539,O14949,P36542,O75489,Q8N8Q8,P03886,P22695,P15954,P10606,P56134 29 +Regulation of gene expression in beta cells 0.8768866528558753 3.609451137931989 0.00030684556345 0.3484636825780024 0.0043709837405744 2 P31751 1 +Runx2 regulates genes involved in cell migration 0.8768866528558753 3.609451137931989 0.00030684556345 0.3484636825780024 0.0043709837405744 2 P31751 1 +Downregulation of erbb2 erbb3 signaling 0.8768866528558753 3.609451137931989 0.00030684556345 0.3484636825780024 0.0043709837405744 2 P31751 1 +N glycan trimming and elongation in the cis golgi 0.8718555785735445 3.5849593825121535 0.0003371306689843 0.3754436769077092 0.0047063441390212 2 P33908 1 +Mitochondrial protein import 0.6644358846654352 3.569382868301763 0.000357823158837 0.3932330634296471 0.0049457537597673 36 O60830,Q9NS69,O14925,Q99595,O96008,P21796,P06576,Q8N4H5,Q9NX63,P12236,Q13505,O43615,Q9Y5J7,Q9Y5J9,Q9Y5L4,Q9Y512,Q3ZCQ8,O60220,Q10713,Q15388 20 +Nrif signals cell death from the nucleus 0.8555785735424694 3.505204620739389 0.0004562564710475 0.4711653042868833 0.0059964045862994 2 Q92542 1 +Organic anion transporters 0.8543947913583925 3.4993731636497896 0.0004663534174906 0.478570511615049 0.0059964045862994 2 Q9UBX3 1 +Release of apoptotic factors from the mitochondria 0.8245042912104192 3.350700672962252 0.0008060738146637 0.6755853567018579 0.0085778085439224 2 Q9NR28 1 +Regulated proteolysis of p75ntr 0.8138502515537163 3.2970318074088905 0.0009771243474812 0.7445509888884698 0.0094806647484626 2 Q92542 1 +Heme degradation 0.9536139768240024 3.2724732811320387 0.0010661094864117 0.774420525825571 0.0101937591988408 4 P30519 1 +Glycosphingolipid metabolism 0.7659899525587808 3.2467593752778763 0.001167270324075 0.8041607583782411 0.010720456397426 18 P10619,Q9NZJ7,P04062,P17900,P16278,P07602,O43681,P06865,Q16739,Q13510,P06280 11 +Slc mediated transmembrane transport 0.7016447787026098 3.219167345861301 0.0012856343247178 0.8340220283441541 0.0112877076560132 23 Q70HW3,P53985,P12236,Q99808,Q8TB61,Q9Y6M7,P35613,Q9UBX3,P30825,Q9H936,Q9Y289,Q96QD8,Q15758,Q8NEW0 14 +Cs ds degradation 0.7972773009766232 3.2128220751674084 0.0013143768681074 0.8405583127791788 0.0113967087445836 2 P06865 1 +The citric acid tca cycle and respiratory electron transport 0.4456902877641336 3.2097023721002897 0.0013287247595652 0.8437242466767199 0.0114499985453894 101 P56385,Q9UDW1,P21796,P20674,Q9P0J1,P00846,Q9H9P8,O75438,O43676,P06576,O75306,P09669,O75964,P00403,Q8N183,O75880,Q9NX14,P35613,P48735,O95168,Q86Y39,O95298,P13073,P53985,Q9NPL8,P24539,O14949,P36542,P09622,Q8N8Q8,O75489,P03886,P22695,P15954,P10606,Q13423,P56134 37 +Diseases associated with glycosaminoglycan metabolism 0.8486671139225235 3.120963036350889 0.0018026065909093 0.9194365015450356 0.0140583173235165 3 Q8NCH0 1 +Chondroitin sulfate dermatan sulfate metabolism 0.8486671139225235 3.120963036350889 0.0018026065909093 0.9194365015450356 0.0140583173235165 3 Q8NCH0 1 +Cristae formation 0.6921649850838374 3.052654782856264 0.0022682671775462 0.958000503749952 0.0172092444557313 20 P36542,Q9Y512,Q13505,P17152,P24539,P00846,P56134,P06576,Q5XKP0,O75964,Q6UXV4,Q9NX63 12 +Downregulation of erbb4 signaling 0.7561408700799084 2.999875181416238 0.0027009026245079 0.9770757751423944 0.0196004717413451 2 P46934 1 +Acyl chain remodelling of pg 0.7546611423498106 2.9921083548600893 0.0027705790682743 0.9792061127968824 0.0198345045092873 2 Q92604 1 +Synthesis of pe 0.819419775014784 2.980063480561365 0.0028818865444875 0.982206496432402 0.0203451556594656 3 Q9HBU6,Q9UG56 2 +Plasma lipoprotein remodeling 0.7522935779816545 2.9796657187232816 0.0028856309602967 0.9822995316353964 0.0203451556594656 2 Q9BU23 1 +Akt phosphorylates targets in the nucleus 0.8167554766133757 2.967104305218992 0.0030061895620914 0.9850487631152888 0.0207754486568298 3 P31749,P31751 2 +Transport of bile salts and organic acids metal ions and amine compounds 0.883747211535067 2.962381792605517 0.0030526899885277 0.9859912493127956 0.0208899765881601 4 P35613,Q8NEW0 2 +Chylomicron assembly 0.746966558153303 2.9515988267976465 0.0031613336368665 0.9879683226384344 0.0214781199459002 2 P07237 1 +Trafficking and processing of endosomal tlr 0.8016811238968224 2.8933863599015455 0.0038111217421192 0.9951583029494364 0.0250958771320684 3 P07858 1 +Intra golgi traffic 0.7413043217361261 2.8769042748588527 0.0040159740173302 0.9963666032914316 0.0261976622812756 16 O95721,O15498,Q13190,P33908,O60476,O95249,O43752,O00461 8 +Mucopolysaccharidoses 0.8608232158720718 2.857979350922432 0.0042634813489681 0.9974317842405088 0.0274277417657121 4 P15586,P16278,P54802 3 +Respiratory electron transport 0.4977038045113209 2.8385681831679386 0.0045316436559692 0.9982366713542652 0.0285749593705583 58 O43674,Q9UDW1,P20674,O96000,O43819,O75438,O43676,O75306,P09669,O00483,P00403,O75880,Q8N183,Q9NX14,Q7L592,P21912,O95168,Q86Y39,O95298,Q9Y6M9,P08574,P13073,Q9NPL8,P14927,O14949,Q9BSH4,P56556,Q8TB37,O75489,Q8N8Q8,P03886,P22695,P15954,P10606,P51970,O14548 36 +Presynaptic function of kainate receptors 0.7244746966558191 2.831998689716729 0.0046258038224202 0.9984548035170214 0.0285749593705583 2 P63218 1 +Inwardly rectifying k channels 0.7244746966558191 2.831998689716729 0.0046258038224202 0.9984548035170214 0.0285749593705583 2 P63218 1 +G protein activation 0.7244746966558191 2.831998689716729 0.0046258038224202 0.9984548035170214 0.0285749593705583 2 P63218 1 +Glucagon type ligand receptors 0.7244746966558191 2.831998689716729 0.0046258038224202 0.9984548035170214 0.0285749593705583 2 P63218 1 +Potassium channels 0.7244746966558191 2.831998689716729 0.0046258038224202 0.9984548035170214 0.0285749593705583 2 P63218 1 +Prostacyclin signalling through prostacyclin receptor 0.7244746966558191 2.831998689716729 0.0046258038224202 0.9984548035170214 0.0285749593705583 2 P63218 1 +Notch3 activation and transmission of signal to the nucleus 0.7813071586162743 2.792668037285643 0.0052275308374039 0.9993356982613072 0.0315914850606746 3 P67809 1 +Abc transporters in lipid homeostasis 0.7781647128862847 2.777021140203997 0.005485961072086 0.9995377874229912 0.032294119226344 3 P40855 1 +Endosomal vacuolar pathway 0.8377257921231825 2.7514083170822294 0.0059339627741625 0.999753583561356 0.0339500493144711 4 P10321,P01889,Q9UIQ6 3 +Mitochondrial calcium ion transport 0.7180265115900963 2.7424224378594424 0.0060987851316363 0.9998045043292716 0.0344692471407461 16 P45880,O95202,Q9BPX6,P21796,Q10713,Q9Y277,Q8IYU8 7 +Ptk6 regulates proteins involved in rna processing 0.7649496743635322 2.710888613721044 0.0067103163927237 0.9999172074754438 0.0370260936136063 3 P23246,O75525 2 +Assembly of the hiv virion 0.7010949985202762 2.705765687437289 0.0068147110701954 0.9999285062123802 0.037406863669197 2 Q9H9H4 1 +Glycosaminoglycan metabolism 0.7278240557114272 2.70004338425705 0.0069330434500085 0.9999394617626234 0.0376336411646742 15 Q8TB61,Q8NCH0,P15586,O43505,Q7LGA3,P06865,P16278,P54802 8 +Signaling by activin 0.6978395975140615 2.6880318793358637 0.0071874534396048 0.999957665874116 0.0384495702767331 2 P27361 1 +Signaling by nodal 0.6978395975140615 2.6880318793358637 0.0071874534396048 0.999957665874116 0.0384495702767331 2 P27361 1 +Sphingolipid de novo biosynthesis 0.8190846765365012 2.687976877890523 0.0071886374227989 0.999957736293642 0.0384495702767331 10 P51648,O95470,Q96G23,P27544 4 +Activated notch1 transmits signal to the nucleus 0.7563647128478386 2.667637029686279 0.0076386732418536 0.999977556831244 0.0397895068866704 3 Q92542,P78536 2 +Linoleic acid la metabolism 0.6889612311334755 2.6394697604517945 0.0083035830825217 0.9999911950528224 0.0413992927971442 2 O95864 1 +Metabolism of porphyrins 0.83326927524658 2.6177942858033747 0.0088500139909262 0.9999959208156944 0.0439666175492277 9 P09601,P30519 2 +Glycogen storage diseases 0.7439831631659581 2.6048527737778477 0.00919137458387 0.9999974780817952 0.0451801370390234 3 P10253 1 +Class i peroxisomal membrane protein import 0.7684667057830534 2.5809637830292904 0.009852491731102 0.999999006749349 0.0482599244091875 11 Q9Y5Y5,P51648,Q9NR77,Q5T8D3,O43808,P40855,O75381 7 +Keratan sulfate degradation 0.7977494817885639 2.563609257429195 0.0103590091689713 0.9999995137776736 0.0496947656353403 4 P15586,P16278,P06865 3 +Integrin cell surface interactions 0.7961633594315232 2.556069105973952 0.0105862092471478 0.9999996471165242 0.050266490166729 4 P35613 1 +Collagen degradation 0.7335679091809133 2.551665814013008 0.0107209296202723 0.9999997082074584 0.0505854393777161 3 P07858 1 +Pregnenolone biosynthesis 0.8440692054851832 2.5408513127607395 0.0110582935484873 0.9999998187462484 0.0516300260658471 5 O95772,Q14849 2 +Glycerophospholipid biosynthesis 0.5680557177163277 2.5268020467680157 0.0115106361377157 0.9999999042997804 0.0528662485346404 29 Q9UG56,O75131,Q9NQZ5,P35790,Q9BVG9,Q96N66,P48651,Q8IV08,Q9HBU6,Q8N2A8,Q86UL3,O95674,Q9NPH0,Q8NF37,Q9HCL2,Q92604,P43304 17 +Ire1alpha activates chaperones 0.5843354422966347 2.520398842869009 0.0117221926096431 0.9999999290186812 0.0528662485346404 26 Q9NWM8,Q9Y5M8,O43731,O14773,P43307 5 +Hs gag degradation 0.788569736452466 2.519875356656487 0.0117396397175777 0.9999999307466544 0.0528662485346404 4 P08236,P16278,P54802 3 +Ion channel transport 0.5589774924701526 2.5089520592998182 0.0121089917177339 0.999999958903067 0.0541799757626813 30 P16615,P05023,Q96PU5,Q9C0H2,P98194,Q9HD20,P61421,Q93050,P51798,P27105,P51790,Q9Y487 12 +Transport of inorganic cations anions and amino acids oligopeptides 0.7537622946975696 2.504528334432788 0.0122614783749623 0.9999999668700988 0.0545238959201713 11 Q9Y6M7,Q70HW3,Q9UBX3,Q96QD8 4 +Nuclear signaling by erbb4 0.784533935389635 2.5005752839132795 0.0123991776496581 0.9999999727294266 0.0545238959201713 4 P16949,Q92542 2 +Prevention of phagosomal lysosomal fusion 0.7214328004736521 2.489262717093094 0.0128008334851197 0.9999999845448614 0.0558436360788348 3 P20339,P51149 2 +Inla mediated entry of listeria monocytogenes into host cells 0.6614382953536597 2.487074893487336 0.0128798281425084 0.9999999861784274 0.0558596659281097 2 P35222 1 +Cytochrome p450 arranged by substrate type 0.7209838134371516 2.4869448772099108 0.012884536123819 0.9999999862701474 0.0558596659281097 3 Q16850 1 +Mitophagy 0.7488995077566165 2.479099275972391 0.0131714639996658 0.9999999908501828 0.0565765038262569 11 Q9NS69,P21796,Q15388,Q8IWA4,Q8N4H5 5 +Clec7a dectin 1 induces nfat activation 0.6593666765315229 2.475490005391212 0.0133053485739882 0.9999999924290124 0.0565943967901233 2 O43865 1 +Calcineurin activates nfat 0.6593666765315229 2.475490005391212 0.0133053485739882 0.9999999924290124 0.0565943967901233 2 P62942 1 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7338513459696951 2.474620248321747 0.0133377912205949 0.999999992768676 0.0565943967901233 12 P51648,P46379,P49069,P09601,Q13190,P05067,P50402 7 +Mitochondrial biogenesis 0.5289153609009605 2.4459140195467297 0.0144485452288587 0.999999998499253 0.0603897279625353 34 P36542,Q9Y512,Q13505,P17152,P24539,P16220,Q04837,P00846,P48735,P56134,P06576,Q5XKP0,O75964,Q6UXV4,Q9NX63 15 +Pre notch processing in golgi 0.7721930860405075 2.441281667188042 0.0146352349454099 0.9999999988480016 0.0609874268172905 4 Q15363,Q9UBV2 2 +Cd28 dependent pi3k akt signaling 0.7650278770310781 2.406663102513958 0.0160990134564402 0.9999999998554064 0.0659498956404961 4 P31751 1 +Inflammasomes 0.760225130708895 2.3833795005087297 0.017154499581812 0.9999999999676844 0.0688151764833609 4 P09601 1 +Purinergic signaling in leishmaniasis infection 0.760225130708895 2.3833795005087297 0.017154499581812 0.9999999999676844 0.0688151764833609 4 P09601 1 +The nlrp3 inflammasome 0.760225130708895 2.3833795005087297 0.017154499581812 0.9999999999676844 0.0688151764833609 4 P09601 1 +Suppression of apoptosis 0.6980461811722845 2.367674650484397 0.0179002692388168 0.9999999999888004 0.0713965024496808 3 P23246,P27361 2 +Metabolism of lipids 0.3636606883779837 2.351952536851775 0.0186751577130002 0.999999999996279 0.0740639777481485 198 P10619,P51648,P50897,Q9BWD1,Q15125,O15269,Q16850,Q8N2A8,Q16739,Q13510,P17900,P16278,P27544,Q14739,Q9P035,P20339,Q8IV08,Q9HBU6,P07602,O15254,Q9NPH0,Q86UL3,O95772,Q14849,Q15800,Q9UMR5,Q9UKU0,Q14534,Q9UG56,Q15067,P04062,P38435,Q9BVG9,Q9HCL2,Q96G23,Q71SY5,Q15392,Q15165,O95470,Q9NZJ7,Q96N66,O43808,O75845,P30536,Q10713,P06865,P06280 47 +Pink1 prkn mediated mitophagy 0.8010290460320648 2.340151444997721 0.0192759216937128 0.9999999999984174 0.0762299906074309 8 Q9NS69,P21796,Q15388,Q8IWA4,Q8N4H5 5 +Keratan sulfate keratin metabolism 0.7979857819905156 2.3305656612346644 0.0197762739363425 0.9999999999992236 0.0779877921331473 5 P15586,O43505,P16278,P06865 4 +Heparan sulfate heparin hs gag metabolism 0.7888033175355386 2.2880404122025255 0.0221351678105434 0.9999999999999732 0.0848920172074689 5 P08236,Q7LGA3,P54802,P16278 4 +Class b 2 secretin family receptors 0.6801568079319222 2.2734823585887463 0.0229971280434011 0.999999999999992 0.0867675425637513 3 P63218 1 +Rab geranylgeranylation 0.5576850002954049 2.255402331339139 0.0241080865492886 0.9999999999999984 0.0907139860453017 24 Q15907,P51148,P61020,P20339,P51151,P61026,P61106,Q969Q5,Q9H0U4,P51149,P20340,Q9BZG1,P61019 13 +Rhog gtpase cycle 0.4991415575873872 2.248493508478872 0.0245447385656096 0.9999999999999992 0.0919601116378903 37 O75489,Q14739,O15498,Q13190,O15173,O95202,Q86Y07,P49257,Q86XL3,P50402 10 +Vitamin d calciferol metabolism 0.7797735786843459 2.246019607017347 0.0247027520517255 0.9999999999999992 0.0919601116378903 5 P38435,P04062 2 +Selective autophagy 0.5193872179593255 2.244452344060478 0.0248033118748527 0.9999999999999994 0.0920888919608894 31 Q9NS69,P21796,P08670,Q15388,Q8N4H5 5 +O linked glycosylation of mucins 0.7263843648208406 2.217513477988969 0.0265880230717407 1.0 0.0965748555312034 4 O43505,Q10471,Q10472 3 +Phospholipid metabolism 0.4753507147625688 2.2037828117290603 0.0275396219446566 1.0 0.0993418920794332 46 P48651,Q8N2A8,Q8IY17,Q92604,P43304,O75131,Q8TBX8,P20339,Q86UL3,Q9HBU6,Q8IV08,O95674,Q9NPH0,Q8NF37,Q9UG56,Q9BVG9,Q9HCL2,Q9NTJ5,Q9BTU6,Q9NQZ5,P35790,Q96N66,Q10713 23 +Cargo concentration in the er 0.6409162801182369 2.191440305211362 0.0284199451084077 1.0 0.1009522732095093 15 Q12907,P49755,P53634,Q13190,Q5JRA6,Q15363,P49257,Q96PC5 8 +Glutamate neurotransmitter release cycle 0.6644934512208426 2.1901665362251506 0.0285121611940759 1.0 0.1010227843323097 3 Q96QD8 1 +Intra golgi and retrograde golgi to er traffic 0.3725929895370922 2.1860568055731866 0.0288114496193332 1.0 0.1018247687812385 103 Q9P2W9,P49755,P24390,Q10472,O95721,O15260,Q9H0B6,Q9BVK6,O15498,P33908,Q13190,O60499,O43731,Q15363,O95249,O43752,O00461 17 +Camk iv mediated phosphorylation of creb 0.6601539372409757 2.1669449286856772 0.0302390535680188 1.0 0.1052711191544994 3 Q13555,P16220 2 +Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.6601539372409757 2.1669449286856772 0.0302390535680188 1.0 0.1052711191544994 3 Q13555,P16220 2 +Heme biosynthesis 0.7622908903001904 2.1640912456711434 0.0304573472521487 1.0 0.1057601680591579 5 P22830 1 +Formation of atp by chemiosmotic coupling 0.7149122376653587 2.162344369382288 0.0305916421306382 1.0 0.1057601680591579 10 P36542,P24539,P00846,P56134,P06576,O75964 6 +Incretin synthesis secretion and inactivation 0.7148356529463932 2.160185274132429 0.030758329679096 1.0 0.1057601680591579 4 P67812,P61009,Q15005 3 +Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.7148356529463932 2.160185274132429 0.030758329679096 1.0 0.1057601680591579 4 P67812,P61009,Q15005 3 +Class a 1 rhodopsin like receptors 0.7855090228012308 2.1558279873457824 0.0310970992272197 1.0 0.1061407103207792 7 P07602,P42892,P05067 3 +Peptide ligand binding receptors 0.7855090228012308 2.1558279873457824 0.0310970992272197 1.0 0.1061407103207792 7 P07602,P42892,P05067 3 +Reduction of cytosolic ca levels 0.6560094730609873 2.144710930376996 0.0319759664278094 1.0 0.1073039642625527 3 P16615,P20020 2 +Platelet calcium homeostasis 0.6560094730609873 2.144710930376996 0.0319759664278094 1.0 0.1073039642625527 3 P16615,P20020 2 +Iron uptake and transport 0.5873742308404957 2.133950865887095 0.0328468030490078 1.0 0.1083939756474787 18 P09601,P30519,Q9Y487 3 +Er quality control compartment erqc 0.7049527184835087 2.1108351376920615 0.0347864847777985 1.0 0.113197978437778 4 Q9UBV2,Q9GZP9 2 +Tp53 regulates metabolic genes 0.478156297465687 2.0973573080968033 0.0359619572992422 1.0 0.1164800287465015 41 P31749,P13073,O75880,Q8N8Q8,Q9Y3B8,Q15382,P62258,P20674,P31751,Q6IAA8,P15954,P10606,Q9NQ88,P54619,P09669,O14548,Q9UHA4,P00403 18 +Gpcr ligand binding 0.6999768401933973 2.084349854499043 0.037128355586685 1.0 0.1194619845643968 10 P07602,P42892,P05067 3 +Cholesterol biosynthesis 0.5911172038788943 2.0606242402174733 0.0393389023424051 1.0 0.1253815243607249 17 Q9BWD1,Q15125,O75845,Q16850,Q15800,Q15392,Q14534 7 +Beta oxidation of pristanoyl coa 0.69410719573585 2.0563715741190496 0.0397467140849163 1.0 0.1263927400057932 4 O14734,O15254,P22307 3 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.5364304362429893 2.017142895889635 0.0436806032507721 1.0 0.1349073498630043 21 Q02818,Q07065,O43852,Q15293,P05067,Q5JRA6,Q9BTY2,O76024,P07942 9 +Nicotinamide salvaging 0.629441775316715 2.000890206637437 0.0454042231969833 1.0 0.1396129858656139 3 P43490 1 +Ion transport by p type atpases 0.6561249686620573 1.979358110022249 0.0477757013233863 1.0 0.1440494147893032 11 P16615,P05023,P20020,P05026,P98194,Q9HD20,P54709 7 +Antigen presentation folding assembly and peptide loading of class i mhc 0.575166942435591 1.956594147115246 0.050395203696431 1.0 0.1495795478403178 17 Q03518,P04439,Q6P179,P10321,P01889,Q9Y6B6,P51572,Q9NZ08 8 +Organelle biogenesis and maintenance 0.35708451906404 1.9536546073911616 0.0507420779351941 1.0 0.1500254165389999 100 P56385,Q99996,Q9H6D7,Q15154,P00846,O94927,P06493,P06576,Q8NCM8,Q5XKP0,A6NIH7,O75964,P50991,Q9BV73,Q9NX63,Q7Z4L5,Q15019,Q13505,Q04837,P48735,P54619,P41208,O43805,Q6UXV4,O43924,Q9Y512,Q92973,Q13409,P62258,Q66GS9,P24539,P17152,P36542,P16220,O75935,Q9NVH1,Q10713,P56134,O95684 39 +Cytoprotection by hmox1 0.3940825699934603 1.9528919987917608 0.0508323939992456 1.0 0.1500254165389999 67 P13073,P28074,O75880,Q8N8Q8,P09601,O00231,P20674,P30519,Q8TCT9,Q9UL46,P15954,P10606,O43242,P61289,P09669,P28072,P00403 17 +Processing of smdt1 0.6505691548560256 1.9485561717821376 0.0513484505027206 1.0 0.1512287698350169 11 Q99623,Q9NWR8,Q8NE86,Q9BPX6,Q9Y4W6,Q10713,Q8IYU8 7 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.7536138250024531 1.9097462157172105 0.056165897318718 1.0 0.1623345603663154 6 P10321,P01889 2 +Regulation of localization of foxo transcription factors 0.7302300781224457 1.8963930157591795 0.0579080947308079 1.0 0.1659952777088457 7 Q9Y3B8,P31751 2 +Amino acid transport across the plasma membrane 0.7042539652086844 1.8867960832588415 0.059187758147069 1.0 0.1675986011628972 5 Q96QD8,Q15758,P30825 3 +Synthesis of pa 0.7253268964256345 1.873045294363149 0.0610621305980316 1.0 0.1715145559654974 7 Q8N2A8,Q9NPH0,Q9HCL2 3 +Wax and plasmalogen biosynthesis 0.6557840984966793 1.861403898288153 0.0626871604958607 1.0 0.1757254539201237 4 O15228,O00116 2 +Interleukin 4 and interleukin 13 signaling 0.6205222176594549 1.8437856708802631 0.0652143817949073 1.0 0.1809896813087219 12 P09601,P31749,P08670 3 +Metabolism of fat soluble vitamins 0.7171447695135674 1.8339662690386456 0.0666590013549979 1.0 0.1817499333819865 7 Q8N0U8 1 +Metabolism of steroid hormones 0.7166986939277984 1.8318315530423104 0.0669765207110264 1.0 0.1822596937867308 7 O95772,Q14849 2 +Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.6482084690553672 1.8224122035064043 0.0683924642879438 1.0 0.1846728822939451 4 O14734,P22307,P51659 3 +Lysosome vesicle biogenesis 0.6047676610867224 1.819702439019323 0.0688043316980042 1.0 0.1854263456571697 13 P15586,P09496,O43633,P05067 4 +Copi dependent golgi to er retrograde traffic 0.4134046706761122 1.810240877892953 0.0702584409822 1.0 0.1886168915599062 53 Q9P2W9,P24390,O15260,Q9H0B6,Q9BVK6,O43731,Q15363 7 +Wnt ligand biogenesis and trafficking 0.7267015878143966 1.7856085324983273 0.0741626644046313 1.0 0.1964536613071449 6 Q5T9L3 1 +Neutrophil degranulation 0.3326073569051642 1.7682196219232496 0.0770241950970482 1.0 0.2028788233122252 187 P10619,P07858,O00231,P01889,P30519,P15586,Q9BTY2,O00571,Q9NQX7,Q969Q5,O75874,P27105,Q13510,P17900,P16278,O95721,P53634,P04439,O00264,O15260,Q8WVQ1,O75629,P07602,P11279,P61916,P14174,O15126,O95298,P10321,Q93050,Q08722,Q9H0U3,P08236,P13473,O00584,P61020,Q07065,Q92542,Q9NZJ7,P04066,O43242,P10253,O43681,P42785,P06280 45 +Response to elevated platelet cytosolic ca2 0.4500812982594099 1.760247648467757 0.0783658262528981 1.0 0.2056366418215146 34 Q96JJ7,O43852,Q92520,Q9NZJ7,Q8NBX0,P05067,P10909,P07602,Q9NUQ9,Q9Y6I9,O94919 11 +Diseases of carbohydrate metabolism 0.660342824786737 1.7582283893774977 0.0787086566088537 1.0 0.2061487516434517 9 P15586,P16278,P10253,P54802 4 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.6988737403675171 1.7461820428908632 0.0807793241165715 1.0 0.2103879411692795 7 P31749,P00533,P16220,P31751,O14980,P27361 6 +Signaling by notch2 0.5810614807603769 1.733460871769691 0.083013786346332 1.0 0.2154038024897389 3 Q92542 1 +Peroxisomal lipid metabolism 0.5777873898330899 1.7280257334952425 0.0839836108726337 1.0 0.216711868351565 14 P51648,Q15067,Q5T8D3,O43808,O15254 5 +Cytochrome c mediated apoptotic response 0.6257929893616511 1.706215683355882 0.0879679297681677 1.0 0.224603022510011 4 Q9NR28,P27361 2 +Formation of apoptosome 0.6257929893616511 1.706215683355882 0.0879679297681677 1.0 0.224603022510011 4 Q9NR28,P27361 2 +Transferrin endocytosis and recycling 0.6047743740587666 1.6910959410418125 0.0908184803151748 1.0 0.2300954601088639 11 Q9Y487 1 +Methionine salvage pathway 0.5718760085560272 1.6819343873429344 0.0925815636657123 1.0 0.2332921712587264 3 Q9BV57 1 +Insulin receptor recycling 0.6204467005450772 1.6583006202195278 0.0972568039046932 1.0 0.2414789658538016 10 Q9Y487 1 +Ros and rns production in phagocytes 0.6410850339994631 1.6576541625977848 0.0973872906702653 1.0 0.2414789658538016 9 Q9Y487 1 +Basigin interactions 0.698581791443553 1.6543857454476778 0.0980491608764793 1.0 0.2426890577722785 6 P35613,P53985,P54709,P05026 4 +Interaction between l1 and ankyrins 0.6117856085282709 1.6330120854158512 0.1024664549163789 1.0 0.2517881000537393 4 Q13813,Q12955,O15020 3 +Ca2 pathway 0.6523441639815134 1.6322487344410703 0.1026270980878063 1.0 0.2517881000537393 5 P63218,Q9UBI6,P35222 3 +Nicotinate metabolism 0.6109230695025594 1.628490329466339 0.1034209581133289 1.0 0.2530645148905043 4 P43490 1 +Regulation of beta cell development 0.6045848983036244 1.5952151832188215 0.1106641246147126 1.0 0.2667960727324923 4 P31751 1 +Synthesis of very long chain fatty acyl coas 0.6486514316282886 1.5943330726328362 0.1108614539068404 1.0 0.2667960727324923 8 Q9P035,Q9UKU0 2 +Alpha oxidation of phytanate 0.6440949350564948 1.591289206038092 0.1115445048678764 1.0 0.2667960727324923 5 P51648 1 +Tysnd1 cleaves peroxisomal proteins 0.6425804951791374 1.5837559027261487 0.1132492778340714 1.0 0.2702495587288269 5 P22307,O00116,Q15067 3 +Synthesis of pg 0.6019001494591784 1.5810953898420856 0.1138562286894744 1.0 0.2712342922363588 4 Q8N2A8,Q8IV08 2 +Asparagine n linked glycosylation 0.3300326069055768 1.5691953046911746 0.1166024379485932 1.0 0.2763616356133042 122 P10619,O60762,Q9UBV2,Q9GZP9,P24390,O15498,Q13190,O43731,Q9BT22,O15027,P16278,Q2TAA5,Q96AA3,P53634,Q9BUN8,O60476,P49257,Q13438,Q96PC5,Q9UJW0,O75340,Q9BVK6,Q13409,P33908,Q15363,Q9H0U3,Q8N6T3,Q9Y6B6,Q9NR45,P46977,Q12907,P49755,Q86YN1,O75935,P04066,Q5JRA6,O95249,Q9H0U4,P04843 39 +Unfolded protein response upr 0.417980726485591 1.567761728372356 0.1169367496740214 1.0 0.2765558690652059 43 Q9NWM8,Q9Y5M8,O43731,O14773,P43307 5 +O linked glycosylation 0.6784124648853903 1.559391790205495 0.1189036782360721 1.0 0.2802349259186185 6 O43505,Q10471,Q9Y2G5,Q10472 4 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.5975506043632064 1.558189429678254 0.1191883499570778 1.0 0.2802349259186185 4 P00374 1 +Elastic fibre formation 0.5022195915951541 1.5507383771285577 0.1209643935938102 1.0 0.2828581129932314 2 P55081 1 +Molecules associated with elastic fibres 0.5022195915951541 1.5507383771285577 0.1209643935938102 1.0 0.2828581129932314 2 P55081 1 +G beta gamma signalling through pi3kgamma 0.6343937652267244 1.5429616219587434 0.1228400878752018 1.0 0.2867638171802371 5 P31749,P63218,P31751 3 +Striated muscle contraction 0.654598974563346 1.5307090848804303 0.1258413074716053 1.0 0.2918180485554171 7 P09493,P08670 2 +Metabolism of cofactors 0.6530011672718529 1.5228670958840511 0.1277919593675007 1.0 0.2943854377508763 7 O75208,P00374,O75874 3 +Thromboxane signalling through tp receptor 0.5411014034713428 1.507774661128951 0.1316122094055705 1.0 0.2997237264766336 3 P63218 1 +Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.6486875452913279 1.5016754198467588 0.1331809549232441 1.0 0.3026558784009616 7 O95864,Q15067,P22307,P51659,O14734 5 +Interleukin 35 signalling 0.4933412252145684 1.4960747792083815 0.1346341694032926 1.0 0.3026558784009616 2 P27824 1 +Interleukin 27 signaling 0.4933412252145684 1.4960747792083815 0.1346341694032926 1.0 0.3026558784009616 2 P27824 1 +Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.4933412252145682 1.4960747792083795 0.1346341694032931 1.0 0.3026558784009616 2 P62993 1 +Cardiac conduction 0.570609847392985 1.4952273107391028 0.134855128211154 1.0 0.3026652073677992 11 P16615,Q99996,P05023,P20020,P05026,O43865,P54709 7 +Copi mediated anterograde transport 0.3808927134917575 1.487496043641326 0.1368838473720841 1.0 0.3063010003034305 54 P49755,P24390,Q9BVK6,O15498,O43731,Q15363,O95249 7 +Cellular response to chemical stress 0.3464658400911554 1.468912373799509 0.1418565579939255 1.0 0.3149393178774909 76 P13073,P28074,O75880,Q8N8Q8,P09601,O00231,P20674,P30519,Q8TCT9,Q9UL46,P15954,O43242,P10606,P61289,P09669,P28072,P00403 17 +Activation of bad and translocation to mitochondria 0.6053230251710586 1.468740551374785 0.1419031740293279 1.0 0.3149393178774909 9 Q9Y3B8,P31749,P31751 3 +Transport to the golgi and subsequent modification 0.3480159446036271 1.460719416861641 0.1440924581988563 1.0 0.3182801766544357 79 P24390,O15498,Q13190,O43731,O15027,P53634,O60476,P49257,Q96PC5,Q9UJW0,Q9BVK6,Q13409,P33908,Q15363,Q8N6T3,Q12907,P49755,O75935,P04066,Q5JRA6,O95249,Q9H0U4 22 +Complex i biogenesis 0.4216369712757579 1.448059557832745 0.1476003947447031 1.0 0.3219533610368836 32 O95298,Q9Y6M9,P56556,Q8TB37,Q8N183,Q9NPL8,Q9NX14,O75489,O43674,P03886,O96000,O95168,Q7L592,P51970,O75438,O43676,O75306,Q86Y39 18 +Transport of vitamins nucleosides and related molecules 0.6010274944498286 1.445884043124218 0.1482097282408077 1.0 0.3227781288988573 9 Q9Y289,Q99808,P12236,Q8TB61 4 +Initiation of nuclear envelope ne reformation 0.4741669240792128 1.4398517787246008 0.1499093382969942 1.0 0.3254641310460404 19 Q14739,P42167,Q86Y07,Q8IXJ6,P06493,Q86XL3,P50402 7 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.6344841105061703 1.4316978231751225 0.1522303196688512 1.0 0.328969666319609 7 Q9NR77 1 +Rac2 gtpase cycle 0.4111106405719713 1.4277680493006282 0.1533586320751456 1.0 0.329428391788809 36 Q9Y512,Q13505,Q14739,O15173,Q86Y07,P49257,Q86XL3,P50402 8 +Tryptophan catabolism 0.4741047647232989 1.3770419009487698 0.1684992935917839 1.0 0.3495171082527941 2 P08195 1 +Autophagy 0.3737793128118482 1.3726698565587836 0.1698550041799889 1.0 0.3498838221727939 53 Q9NS69,O43633,P49815,Q13501,Q13409,O96008,Q15382,P21796,Q9UHA4,Q6IAA8,P08670,Q15388,P54619,Q7Z3C6,Q8IWA4,P13473,Q8N4H5 17 +Metabolism of steroids 0.3809751023046102 1.359059774635992 0.1741276480829201 1.0 0.3564255083926048 50 P04062,Q9BWD1,Q15125,P38435,O75845,Q9HCL2,Q16850,P30536,Q15800,Q14849,O95772,Q15392,Q14534 13 +Apoptotic factor mediated response 0.63476065700556 1.351729614841932 0.1764618276070471 1.0 0.3601472388003475 6 P27361,Q9NR28,Q07812 3 +Regulation of tp53 expression and degradation 0.5249906610283157 1.3378522799345132 0.1809445956192701 1.0 0.3671492085530539 13 P31749,P31751,P24941 3 +Thrombin signalling through proteinase activated receptors pars 0.5910056373845258 1.3250515073632672 0.185154068262682 1.0 0.3738487563026511 5 P63218,Q9UBI6,P27361 3 +Ion homeostasis 0.5600830784524314 1.324558649801343 0.1853175783391365 1.0 0.3738487563026511 10 P16615,P05023,P20020,P05026,O43865,P54709 6 +Runx2 regulates bone development 0.5895108570604773 1.3175033492606152 0.1876699591492374 1.0 0.377503260767054 5 Q96PK6,P27361 2 +Regulation of innate immune responses to cytosolic dna 0.5068087625814125 1.3114864013012897 0.1896934850881046 1.0 0.3799312843371508 3 Q9NZI8,P19474 2 +Signaling by erbb4 0.5558909999113907 1.3011445361011782 0.193208985864115 1.0 0.3858651563180323 10 P16949,Q92542,P46934,P78536,Q96J02 5 +N glycan trimming in the er and calnexin calreticulin cycle 0.4879528661543456 1.2949541032121346 0.1953360628725091 1.0 0.3895559196714611 16 Q9BUN8,Q9UBV2 2 +Collagen biosynthesis and modifying enzymes 0.5243645627311877 1.2775995294113351 0.2013906665910929 1.0 0.4004862828506634 12 P13674,O75718,Q32P28 3 +Cytosolic sulfonation of small molecules 0.5417468013631845 1.2615991026967892 0.2070930792237215 1.0 0.4083360714637222 4 Q8TB61 1 +Runx2 regulates osteoblast differentiation 0.5356825584838502 1.229161079848941 0.2190114180827045 1.0 0.4258792968031638 4 P27361,P28482,Q9UPW6 3 +Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.5773980830090659 1.22908197917003 0.219041070991885 1.0 0.4258792968031638 8 Q9Y3B8,Q07812 2 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.5714194124112959 1.2260125072802812 0.2201939683930487 1.0 0.4269640779046117 5 P12235,Q99808,P12236 3 +G alpha i signalling events 0.4235680039884971 1.2139120733487327 0.2247813020175375 1.0 0.4319317583040752 24 Q9UBI6,Q00535,Q9NZJ7,P63218,P13861,P16220,P05067,P07602,O43865,Q9NRV9,P28482 11 +Stimuli sensing channels 0.5395775637630915 1.209849560552665 0.22633662481338 1.0 0.4328300386842171 10 Q9C0H2,P27105,P51790,Q96PU5 4 +Killing mechanisms 0.4424385912992085 1.1799444415534133 0.2380223126867289 1.0 0.4508536614798852 2 O14641 1 +Activated ntrk2 signals through cdk5 0.442438591299208 1.17994444155341 0.2380223126867302 1.0 0.4508536614798852 2 Q00535 1 +Rhod gtpase cycle 0.4081581127427974 1.175148018822474 0.2399355023529734 1.0 0.4538617361581991 28 Q14739,Q9Y6M7,O15173,P42167,Q86Y07,Q86YQ8,P49257,Q9H0H5,P50402 9 +Cell surface interactions at the vascular wall 0.4683113257241872 1.1629914787902953 0.2448329597206142 1.0 0.4615294371315206 16 P14174,P35613,P53985,Q08722 4 +E3 ubiquitin ligases ubiquitinate target proteins 0.4644476747001758 1.1369756428976985 0.2555484680702644 1.0 0.4794968567554961 16 Q9BUN8,O75381,Q14527,Q9GZS3 4 +Foxo mediated transcription 0.4997196269647931 1.129604332902182 0.2586429844340285 1.0 0.4846518204965153 12 Q9Y3B8,P31751 2 +Plasma lipoprotein assembly 0.4740115729596546 1.1226408224344044 0.2615900704292087 1.0 0.489517075494873 3 P07237 1 +Copii mediated vesicle transport 0.3937210275969364 1.1190107372197424 0.2631355583963246 1.0 0.4905873904170885 30 Q12907,P49755,P53634,O15498,Q13190,Q15363,P49257,O15027 8 +Pre notch expression and processing 0.505423806193792 1.1152909587360902 0.2647257585655256 1.0 0.4907797595716783 11 Q15363,Q9UBV2 2 +Atf6 atf6 alpha activates chaperones 0.4317845516425066 1.113542936116519 0.2654753187457821 1.0 0.4908656224756448 2 P14625 1 +Atf6 atf6 alpha activates chaperone genes 0.4317845516425066 1.113542936116519 0.2654753187457821 1.0 0.4908656224756448 2 P14625 1 +Energy dependent regulation of mtor by lkb1 ampk 0.5194911632815375 1.0972208849520677 0.2725448455795218 1.0 0.4996331458402013 10 Q9UHA4,Q15382,P54619,Q6IAA8 4 +Amyloid fiber formation 0.5501749376110133 1.0883156977399728 0.2764557629157869 1.0 0.5038279961232879 8 Q9Y287,P05067 2 +Hyaluronan uptake and degradation 0.5745170342482558 1.0625799898605233 0.2879724654385498 1.0 0.5207377742904347 6 P08236,P06865 2 +Hyaluronan metabolism 0.5745170342482558 1.0625799898605233 0.2879724654385498 1.0 0.5207377742904347 6 P08236,P06865 2 +Rhoa gtpase cycle 0.359836659706094 1.036659245964258 0.2998946914908822 1.0 0.5346980247446972 46 Q14739,O15498,Q5T8D3,Q13190,O15173,P30519,P42167,Q96HY6,P49257,P27105,P51572 11 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.5231650776356113 1.028145964559889 0.3038811719003926 1.0 0.5410945356797808 9 P09601 1 +Signaling by pdgfr in disease 0.532161974122767 1.0272771686356146 0.3042899699938068 1.0 0.541132226893445 5 O43815,Q13439 2 +Rab gefs exchange gtp for gdp on rabs 0.3864679164092023 1.0203604409434397 0.3075575480400927 1.0 0.5458006070823739 29 P31749,P51148,P61020,P62258,P20339,P51151,P31751,P61026,Q5VZ89,Q9H0U4,P51149,P20340,Q14C86 13 +Signaling by notch3 0.5652978389311656 1.0183546539186952 0.3085094438095381 1.0 0.5465471872564914 6 P67809 1 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.4879174518206089 1.0127646319430894 0.3111725980165492 1.0 0.5495702365039106 11 P07196,P16220,P28482,P27361,Q14168 5 +Activation of smo 0.4155075466114326 1.0122952841061352 0.311396889021915 1.0 0.5495702365039106 2 P48729 1 +Depolymerisation of the nuclear lamina 0.5192929422193577 1.0073459288637865 0.3137685656733469 1.0 0.5522027747144834 9 P42167,P50402,P06493 3 +Trans golgi network vesicle budding 0.3662392341977377 0.9994540224535238 0.3175748011573063 1.0 0.5541680280194995 36 O43633,P55327,P05067,P15586,Q9H3P7,Q9Y5X3,P51809,O60749,P09496,O75976 10 +Creb1 phosphorylation through the activation of adenylate cyclase 0.4921695363010471 0.9964666504424476 0.3190234630592743 1.0 0.5543557540086321 4 P16220 1 +Pka mediated phosphorylation of creb 0.4921695363010471 0.9964666504424476 0.3190234630592743 1.0 0.5543557540086321 4 P16220 1 +Long term potentiation 0.5602819927965133 0.9943243219230816 0.3200649983746113 1.0 0.5543557540086321 6 P07196 1 +Unblocking of nmda receptors glutamate binding and activation 0.5602819927965133 0.9943243219230816 0.3200649983746113 1.0 0.5543557540086321 6 P07196 1 +Ras activation upon ca2 influx through nmda receptor 0.5602819927965133 0.9943243219230816 0.3200649983746113 1.0 0.5543557540086321 6 P07196 1 +Lipophagy 0.4505624629958675 0.987847855330636 0.3232271664163402 1.0 0.5581417471471518 3 P54619,P11142 2 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.4833679980272096 0.986155745787618 0.3240566917474148 1.0 0.5584977057770261 11 Q9BU89,O60725,P38435 3 +Diseases associated with n glycosylation of proteins 0.5562492305385707 0.9750240969626764 0.3295483071051359 1.0 0.563288968371992 6 Q96AA3,Q2TAA5,Q9BT22 3 +E2f enabled inhibition of pre replication complex formation 0.5560316761821199 0.9739834849769208 0.3300647393469123 1.0 0.563288968371992 6 Q9Y619 1 +Fgfr2 alternative splicing 0.4193126683989425 0.9601960820280004 0.3369565383565023 1.0 0.5729492418339552 18 P31483,O43251,P52272,P35269,P19388,Q01085,P31943,P52597 8 +Calnexin calreticulin cycle 0.5096859536097439 0.955812599822554 0.3391669214710502 1.0 0.575549351868558 9 Q9UBV2,Q9GZP9,Q13438 3 +Glucagon like peptide 1 glp1 regulates insulin secretion 0.5517243384677526 0.9533937477088866 0.3403906080770833 1.0 0.5757132216571041 6 P46940,P13861,P63218 3 +Vesicle mediated transport 0.2843488011583563 0.9510348305776628 0.3415866949277868 1.0 0.5766082540739909 276 Q15907,Q9BRG1,P24390,Q14108,Q8TD16,Q9UMX0,O15498,Q13190,P15586,O43731,Q9H3P7,Q92905,Q5VZ89,P40616,P31749,O95721,O43633,P53634,O15260,P53365,P20339,Q8TBA6,P05067,O60476,P49257,P51809,Q96PC5,O60749,P09496,O43752,Q14C86,Q10472,Q99627,Q9BVK6,P55327,P33908,P31751,Q15363,Q96D71,Q9BT78,Q9UIQ6,Q9Y5X3,Q8WTV0,O00461,O75976,Q9P2W9,P49755,P61020,Q9Y3B8,Q9H0B6,O60499,O95249,Q12981 53 +Inactivation of cdc42 and rac1 0.4425695677915966 0.942110474916124 0.3461360821116854 1.0 0.5828781310348768 3 O94813,P60953 2 +Synthesis of pc 0.5149989284926398 0.9407459288530342 0.346835076145358 1.0 0.5833065870005744 5 P35790,Q9NQZ5 2 +Intrinsic pathway for apoptosis 0.3961281764663503 0.9386187287653563 0.3479265334586261 1.0 0.5837805777743293 20 P31749,Q9NR28,Q9Y3B8,P62258,P31751,Q07812 6 +Post translational modification synthesis of gpi anchored proteins 0.519545930026965 0.930309277124918 0.3522109758576328 1.0 0.5878272671711678 8 O60762,O43292 2 +Glucagon signaling in metabolic regulation 0.5128558830516954 0.929974726796823 0.3523841701256089 1.0 0.5878272671711678 5 P63218,P13861 2 +Vasopressin regulates renal water homeostasis via aquaporins 0.5128558830516954 0.929974726796823 0.3523841701256089 1.0 0.5878272671711678 5 P63218,P13861 2 +Robo receptors bind akap5 0.4021899970405513 0.929859735978856 0.3524437124801343 1.0 0.5878272671711678 2 P13861 1 +Golgi to er retrograde transport 0.3083648885712445 0.9235464021828744 0.3557225304948022 1.0 0.5904740220817406 78 Q9P2W9,P24390,Q10472,O15260,Q9H0B6,Q9BVK6,Q15363,O43731 8 +Membrane trafficking 0.2816729235332497 0.8901171241245672 0.3734029989909324 1.0 0.6089609656440907 268 Q15907,Q9BRG1,P24390,Q14108,Q8TD16,Q9UMX0,O15498,Q13190,P15586,O43731,Q9H3P7,Q92905,Q5VZ89,P40616,P31749,O95721,O43633,P53634,O15260,P53365,P20339,Q8TBA6,P05067,O60476,P49257,P51809,Q96PC5,O60749,P09496,O43752,Q14C86,Q10472,Q99627,Q9BVK6,P55327,P33908,P31751,Q15363,Q96D71,Q9BT78,Q9UIQ6,Q9Y5X3,O00461,O75976,Q9P2W9,P49755,P61020,Q9Y3B8,Q9H0B6,O60499,O95249,Q12981 52 +Negative regulation of nmda receptor mediated neuronal transmission 0.5107027890628315 0.8849376699865302 0.3761902495346945 1.0 0.6127906515174253 8 P07196 1 +Scavenging by class a receptors 0.4319123741859144 0.8813993006966845 0.3781017360397491 1.0 0.6151865075891491 3 Q5KU26,P14625 2 +Er to golgi anterograde transport 0.3026772644415513 0.8778352997148514 0.380033104918835 1.0 0.6161744651181111 75 P24390,O15498,Q13190,O43731,O15027,P53634,P49257,Q96PC5,Q9UJW0,Q9BVK6,Q13409,Q15363,Q8N6T3,Q12907,P49755,O75935,Q5JRA6,O95249,Q9H0U4 19 +Plasma lipoprotein clearance 0.4351252817911103 0.8307796875100542 0.406098099594816 1.0 0.6450865759906107 14 O15118,P61916,Q8WTV0 3 +Aryl hydrocarbon receptor signalling 0.4215512137359412 0.8227669298897565 0.4106405460007001 1.0 0.6492120070407444 3 Q15185,O00170 2 +Signaling by ptk6 0.4411872417228608 0.8216763751825273 0.411261108398337 1.0 0.6494575874706772 13 P31749,P24941,P23246,P18031,Q07666,O75525 6 +Signaling by notch 0.3142678533873125 0.7999138540801162 0.42376071037723 1.0 0.6654330165203748 60 P31749,Q9UBV2,P16615,P28074,Q92542,O00231,P67809,P16220,Q9UL46,O43242,Q15363,P61289,P78536,P28072 14 +Adp signalling through p2y purinoceptor 1 0.4165327418235943 0.7945402096851377 0.4268810101409521 1.0 0.6688281595474401 3 P63218 1 +Phase i functionalization of compounds 0.4285661334772439 0.7896034832994667 0.4297593733446427 1.0 0.671829882630595 14 P07099,Q16850,O43169 3 +Growth hormone receptor signaling 0.5140843221141094 0.7750701831774469 0.4382981892831425 1.0 0.6807066160034919 6 P27361,P78536,P18031 3 +Diseases of glycosylation 0.3828980217076992 0.7649719211539707 0.4442882649216348 1.0 0.6868509610527157 19 P10619,O60762,Q96AA3,Q8NCH0,O43505,Q9BT22,P06865,P16278 8 +Vitamin b5 pantothenate metabolism 0.5095359758960417 0.7537959075630191 0.4509717817313103 1.0 0.692039478266146 6 Q9Y289,P22413 2 +Innate immune system 0.2741403257979786 0.7527331422624657 0.4516102899000422 1.0 0.692039478266146 303 P10619,P28074,P07858,O00231,P01889,P30519,P15586,Q9BTY2,O00571,Q9NQX7,P61289,Q969Q5,P27105,O75874,Q13510,P17900,P16278,O95721,P53634,P04439,P09601,O00264,O15260,Q99538,Q9H1D9,O75629,Q8WVQ1,Q8IV08,P05067,P07602,P11279,Q9Y297,P61916,P14174,O15126,Q9Y487,O95298,P10321,Q9UL46,Q93050,P10909,Q08722,Q9H0U3,P08236,P13473,P42785,P28072,P61421,Q9UQB8,O00584,P61020,Q07065,Q92542,Q9NZJ7,Q9BRV8,P16220,P04066,O43242,P10253,O43681,Q9NZQ3,P49721,P06280 63 +Cargo recognition for clathrin mediated endocytosis 0.3399235135474655 0.7442033283555223 0.4567534747562625 1.0 0.6968610390816857 38 Q9UMX0,Q14108,Q99627,Q92905,Q96D71,P51809,P09496 7 +Signaling by hippo 0.4908120924718454 0.7212676427018482 0.4707448610299256 1.0 0.7096758380105574 7 O14641,Q4VCS5,P62258,P31946,Q9UDY2,Q07157 6 +Rap1 signalling 0.4023090586145764 0.7152973149658979 0.4744253473356903 1.0 0.7121511316605891 3 P31946,P63104 2 +Pka activation in glucagon signalling 0.402309058614561 0.7152973149658131 0.4744253473357427 1.0 0.7121511316605891 3 P13861,P10644 2 +Mastl facilitates mitotic progression 0.4688806320048908 0.7118555175274299 0.4765542498603459 1.0 0.7134808722163534 5 O43768 1 +Gastrin creb signalling pathway via pkc and mapk 0.4887587258458707 0.711383764750219 0.4768464568609296 1.0 0.7134808722163534 7 P27361,P00533,P16220 3 +Plasma lipoprotein assembly remodeling and clearance 0.3823272923831553 0.6967787366484023 0.4859412750510543 1.0 0.7189469281236693 18 O15118,P61916,Q8WTV0,P09496 4 +Syndecan interactions 0.435001480604074 0.6964218474368059 0.4861646849203036 1.0 0.7189469281236693 4 P12814,O14936,P05556 3 +Regulation of tp53 activity through association with co factors 0.4324423974011104 0.6833322015123212 0.4943969506800627 1.0 0.728612340556447 4 P31751 1 +Synaptic adhesion like molecules 0.4809869090130249 0.6741552214802186 0.5002126347617637 1.0 0.728612340556447 7 O95197 1 +Extracellular matrix organization 0.3323519712650872 0.67369758798559 0.5005035956567889 1.0 0.728612340556447 36 P13674,O75718,Q32P28,P07858,P35613,P05067,Q08722 7 +Slc transporter disorders 0.3359112492980824 0.6627564045082398 0.5074865787134721 1.0 0.7329880085324904 32 Q9BTX1,P35613,P53985,Q8NFH4 4 +Pyruvate metabolism and citric acid tca cycle 0.3317241546663864 0.6619166926797948 0.5080246131414647 1.0 0.7329880085324904 35 Q13423,P35613,Q9H9P8,P21796 4 +Chl1 interactions 0.3925399644760222 0.6616603215159972 0.5081889392441938 1.0 0.7329880085324904 3 P05556,P11142 2 +Ncam signaling for neurite out growth 0.4658076004982605 0.6583670453114103 0.510302305878719 1.0 0.7344144525842183 8 P27361,O15020,P16220,P28482 4 +Constitutive signaling by akt1 e17k in cancer 0.4529578228684174 0.6564494407660325 0.5115349881899165 1.0 0.735284113665767 9 P31749,P49841,P16220,P31751 4 +Retrograde transport at the trans golgi network 0.3679294760034156 0.6557295539942049 0.5119981497147896 1.0 0.735284113665767 19 P53365,O60499,O43752,P40616 4 +Peroxisomal protein import 0.354119675987204 0.652076582944775 0.5143517696484086 1.0 0.735284113665767 24 Q15067,O15254,O00116,Q13011,O75874,O75381 6 +Peptide hormone metabolism 0.4130910567062458 0.6519465761058411 0.5144356369790613 1.0 0.735284113665767 13 P67812 1 +Mtor signalling 0.3673659228323018 0.6516476659924066 0.5146284906666363 1.0 0.735284113665767 19 P31749,P49815,Q15382,P31751,Q6IAA8,P54619,Q9UHA4 7 +Signaling by insulin receptor 0.3838084966099566 0.6499949642101879 0.51569547445889 1.0 0.7353533016798881 17 Q93050,Q9Y487 2 +Ngf stimulated transcription 0.4247055533061471 0.6440217825310405 0.5195613090544289 1.0 0.7390909900065101 4 P16220 1 +Hemostasis 0.2747430160623321 0.6340901980730467 0.5260219592657402 1.0 0.7462669259501762 126 O43852,P31749,Q96JJ7,Q92520,P35613,P20339,P05067,P07602,Q9NUQ9,Q9Y6I9,P14174,Q6UXV4,P53985,Q8NBX0,P24941,P10909,Q08722,Q8IWA4,Q8N2K0,Q9NZJ7,Q9H0B6,P42785,O94919 23 +Rhobtb1 gtpase cycle 0.3537389848304093 0.6161752836350074 0.5377788392936007 1.0 0.7567936085220429 20 P62995,P08670,Q9BT78,P38159,P07910 5 +Activation of ppargc1a pgc 1alpha by phosphorylation 0.3483279076649972 0.6059967432578638 0.5445169158316436 1.0 0.7601975074289617 2 P54619 1 +Extra nuclear estrogen signaling 0.3846668293584671 0.604914946779526 0.5452355113013985 1.0 0.760388385391361 16 O43815,P31749,Q9UBI6,P63218,P00533,P16220,P31751,O14980,P27361 9 +Fatty acyl coa biosynthesis 0.3843668579281288 0.6029725155010339 0.5465269733622162 1.0 0.7614287972192154 16 Q9UMR5,P50897,Q9UKU0 3 +Rac3 gtpase cycle 0.3253805615842374 0.6021196637197772 0.5470944862754408 1.0 0.7614595242677122 35 Q14739,O15498,O15173,P42167,Q86Y07,P49257,P50402,Q15758,Q9UQB8 9 +Miscellaneous transport and binding events 0.4758518518518547 0.5991263694119096 0.5490886184605916 1.0 0.7627141406676478 6 Q8TDW0,Q9UEY8,Q9H0U3,P35612,P35611 5 +Anchoring of the basal body to the plasma membrane 0.3249490495755566 0.593828365269907 0.552626915120054 1.0 0.765344418162297 34 Q99996,Q15019,Q9H6D7,Q13409,P62258,Q66GS9,O75935,O94927,P06493,P41208,O43805,O95684,Q9BV73 13 +Collagen formation 0.3893599663603306 0.5892434735152904 0.5556979579957244 1.0 0.7657989628450457 15 P13674,P07858,O75718,Q32P28 4 +Sulfur amino acid metabolism 0.4193138818015557 0.5472379849402546 0.5842152430024017 1.0 0.7872244008024641 10 Q9BV57,Q9UBX3 2 +Translation of sars cov 1 structural proteins 0.4628496998758715 0.5411824269501491 0.5883818487051871 1.0 0.7920743112752566 6 Q10472,P49841 2 +Abc family proteins mediated transport 0.2964204121761405 0.5264939135691128 0.5985450797646719 1.0 0.7988230701256998 55 Q9UBV2,Q9GZP9,P28074,O00231,P05198,Q9UL46,O43242,Q9BUN8,Q13438,P40855,P61289,P49721,P28288,P08183,P28072 15 +Wnt mediated activation of dvl 0.3661930136175242 0.5213201625144938 0.6021437576136546 1.0 0.8020922572792574 3 O14641,P19784 2 +Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.4139617724008823 0.5193949106971681 0.6034853796075337 1.0 0.8031130504595968 10 Q9Y3B8,P06493 2 +Phosphorylation of the apc c 0.3978534120701528 0.4999772884790577 0.6170910694208565 1.0 0.8127546356885555 11 Q9UJX3,P30260,P06493 3 +Muscle contraction 0.3307561048147677 0.4992389706406994 0.617611043465363 1.0 0.8127546356885555 27 P16615,Q99996,P05023,P20020,P09493,Q13555,P05026,P08670,P06753,O43865,P60660,P54709,P67936 13 +Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.3950251702694662 0.4977614977445911 0.6186521566004437 1.0 0.8127546356885555 4 Q9Y624,Q9P2M7,P62942 3 +Akt phosphorylates targets in the cytosol 0.4521413069754966 0.4944066199330634 0.6210190397125843 1.0 0.8137470012766566 6 P31749,P49841,P31751 3 +Postmitotic nuclear pore complex npc reformation 0.3344143018966706 0.4891220376369261 0.6247553002990878 1.0 0.8144944529996031 23 Q9BTX1,Q8NFH4,Q92973 3 +Downregulation of erbb2 signaling 0.4306717123002391 0.4888441679785044 0.6249520256418255 1.0 0.8144944529996031 8 P31749,Q9UNE7,Q16543,P31751 4 +Activation of the ap 1 family of transcription factors 0.3594334313163412 0.486582801285782 0.6265540140699368 1.0 0.8144944529996031 3 P27361 1 +Neurotransmitter clearance 0.3264279372595522 0.482576307119498 0.6293966053239792 1.0 0.8165777518887314 2 P21964 1 +Activation of atr in response to replication stress 0.334620679408684 0.4792645678716449 0.6317504253852984 1.0 0.816595920220256 21 P33991,Q9Y619 2 +Activation of bh3 only proteins 0.3824822687395258 0.4736082799571645 0.6357792699060258 1.0 0.8206682937573628 13 Q9Y3B8,P31751 2 +Unwinding of dna 0.4131119126278942 0.457067195580029 0.6476227481737884 1.0 0.8256450743841174 9 Q14566,P33991,Q9BRT9 3 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.4195629253868237 0.4374598067583525 0.6617779190360302 1.0 0.8360560859495911 8 P25054,O14641,P49841 3 +Deactivation of the beta catenin transactivating complex 0.38068506911645 0.4343298758226836 0.6640489118512747 1.0 0.8378513581500656 12 Q9Y297,P31749,P25054,P31751 4 +Cd163 mediating an anti inflammatory response 0.3478389579632885 0.4284827150864288 0.6682997152125052 1.0 0.8393521827796113 3 Q16539,P78536 2 +Rsk activation 0.3769618004145543 0.4133257786491199 0.6793679453670576 1.0 0.8475403500736483 4 Q15418,P27361,P28482 3 +Activation of kainate receptors upon glutamate binding 0.370447142434097 0.3839334585595248 0.7010277669392355 1.0 0.8698975667974869 4 P63218,Q9UBI6,Q15334 3 +Pyruvate metabolism 0.3466473838090301 0.367072833751615 0.7135646905202941 1.0 0.8776531347720975 16 Q9P0J1,P35613,P53985,P21796 4 +Clathrin mediated endocytosis 0.2788057275376336 0.36266702609384 0.7168536344070109 1.0 0.8793740541583367 59 Q9UMX0,Q14108,P61020,Q99627,P20339,Q92905,Q96D71,P51809,P09496,Q14C86 10 +Switching of origins to a post replicative state 0.2766671152301151 0.3598476604883007 0.7189610594056051 1.0 0.8801114843684509 61 P28074,Q9Y619,O00231,P30260,P49721,Q9UL46,P24941,Q96DE5,Q9UJX3,O43242,P61289,Q14566,P33991,P28072,P49736 15 +Nuclear envelope ne reassembly 0.284004154976123 0.3578598847423125 0.7204481725994987 1.0 0.8801114843684509 53 Q9BTX1,O43633,Q92973,Q14739,P42167,Q86Y07,Q8IXJ6,Q8N1F7,Q86XL3,P50402,Q8NFH4 11 +Disorders of transmembrane transporters 0.266601590414069 0.357647616730947 0.7206070391354866 1.0 0.8801114843684509 77 Q9BTX1,Q9UBV2,Q9GZP9,P28074,P53985,P35613,O00231,Q9UL46,O43242,Q9BUN8,Q8N1F7,Q13438,P61289,P49721,Q8NFH4,P28072 16 +Activation of the pre replicative complex 0.3156610579558265 0.3542100585040693 0.7231814660457314 1.0 0.8823774878355081 24 P33991,Q9Y619 2 +Beta oxidation of very long chain fatty acids 0.4180465559666401 0.3526396655492309 0.7243585967474873 1.0 0.8823774878355081 6 Q15067 1 +Response of eif2ak1 hri to heme deficiency 0.3280047365304886 0.3342006487190664 0.7382281545041516 1.0 0.8969247203549136 3 P08243,P05198 2 +Cd28 co stimulation 0.3644623362335829 0.3272159121877884 0.7435045865811363 1.0 0.9017507402799289 11 P31751 1 +Transcriptional regulation by ventx 0.3601578773877177 0.32650055264543 0.7440456712381183 1.0 0.9017507402799289 12 Q9UJX3,P30260 2 +Ub specific processing proteases 0.2611836784846036 0.3249179548172629 0.7452431675697668 1.0 0.9017507402799289 71 P28074,P45880,P21796,Q96K76,Q9Y277,Q15388,P28072 7 +Small interfering rna sirna biogenesis 0.3566492733821155 0.3238177640476152 0.7460760064636947 1.0 0.9017507402799289 4 O75569,Q99598 2 +Adora2b mediated anti inflammatory cytokines production 0.3817216422191301 0.3118751818714161 0.75513538444378 1.0 0.9064221811552168 9 P63218,P13861,P16220 3 +Sialic acid metabolism 0.404709020466345 0.3008150810780626 0.7635555077144751 1.0 0.9133877367347104 6 P10619 1 +Circadian clock 0.3542333991592669 0.296673075977667 0.7667161143373566 1.0 0.9144642709954371 12 Q9Y297,P50416,P43490,P16220 4 +Neurotransmitter release cycle 0.3956644464321576 0.2962021740638489 0.7670756886358574 1.0 0.9144642709954371 7 Q96QD8 1 +Hur elavl1 binds and stabilizes mrna 0.3748149192609925 0.2900155330642632 0.7718043543821949 1.0 0.9193164494176996 5 O14980,Q01105 2 +Adrenaline noradrenaline inhibits insulin secretion 0.3153351080205284 0.2779559185614008 0.7810461976713898 1.0 0.92922878887084 3 P63218 1 +Aurka activation by tpx2 0.2889238114037085 0.2689121707254633 0.7879972709622138 1.0 0.9338235910553908 34 Q99996,Q9H6D7,Q13409,P62258,Q66GS9,O75935,O94927,P06493,P41208,O43805,O95684,Q9BV73 12 +Recruitment of mitotic centrosome proteins and complexes 0.2885046373315258 0.2675197204768765 0.7890690325513261 1.0 0.9343005678046236 36 Q99996,Q9H6D7,Q13409,P62258,Q66GS9,O75935,O94927,P06493,P41208,O43805,O95684,Q9BV73 12 +Defective cftr causes cystic fibrosis 0.2871047942836813 0.2657759785389603 0.7904117443978991 1.0 0.934305499728592 44 Q9UBV2,Q9GZP9,P28074,O00231,Q9UL46,O43242,Q9BUN8,P61289,P49721,P28072 10 +Biological oxidations 0.2879961177034186 0.2590677516207262 0.7955829660410534 1.0 0.9378975663339332 42 Q9NUJ1,P48637,Q9NX62,O43169,Q8TB61,Q99735,Q16850,P07099 8 +Interleukin 12 signaling 0.3002494108648105 0.2583484761231148 0.7961379771530879 1.0 0.9378975663339332 27 P22626,Q9UL46,P51809,O14979,P14174,P52597 6 +Dap12 interactions 0.3927493530980569 0.25642445570674 0.7976231060541064 1.0 0.938854853331815 6 P01889 1 +Epha mediated growth cone collapse 0.3574728039634101 0.2471962623350741 0.804756337789515 1.0 0.9448207866421452 10 O75116,P60660,Q15375 3 +G protein beta gamma signalling 0.3803399582067926 0.2374093870388215 0.8123392080770451 1.0 0.9505662485126194 7 P31749,P63218,P31751 3 +Ldl clearance 0.3409895526943779 0.2324519080164176 0.8161870360459988 1.0 0.9531490338884197 12 O15118,P61916 2 +Interleukin 12 family signaling 0.2934568724640541 0.2302848975920426 0.8178703952552107 1.0 0.9538404943828522 29 P22626,P07237,Q9UL46,Q13126,P51809,O00170,O14979,P20700,P14174,P52597 10 +Flt3 signaling 0.3838035763358107 0.2246299489381085 0.8222671643471982 1.0 0.9567889120837404 6 P31751 1 +Suppression of phagosomal maturation 0.3819745700454734 0.2182864669448293 0.8272059180474984 1.0 0.959119154148096 6 P20339,P51149 2 +Senescence associated secretory phenotype sasp 0.3030457364432503 0.2150727508873318 0.8297105984151698 1.0 0.9604278568719544 19 Q96DE5,Q9UJX3,P30260,P24941 4 +Signaling by ctnnb1 phospho site mutants 0.373332622057155 0.211796575688795 0.8322657401272486 1.0 0.9609950150683532 7 P25054,P49841 2 +Beta catenin phosphorylation cascade 0.373332622057155 0.211796575688795 0.8322657401272486 1.0 0.9609950150683532 7 P25054,P49841 2 +Ctla4 inhibitory signaling 0.3641194817548299 0.2049064580968523 0.8376452094466034 1.0 0.9648124689665496 8 P31751 1 +Eph ephrin mediated repulsion of cells 0.3347099221589875 0.2033022734161077 0.8388987787048403 1.0 0.9654597651046636 12 P09496,Q92542 2 +Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.3540276043129152 0.1964709554876336 0.8442415637868563 1.0 0.9676740579744758 9 Q9UJX3,P30260 2 +Dna damage recognition in gg ner 0.3108121238654012 0.193219080898979 0.8467873959074863 1.0 0.9676740579744758 17 Q92905,P41208,Q99627 3 +Rhobtb3 atpase cycle 0.323363932484443 0.1930023144047662 0.8469571555357911 1.0 0.9676740579744758 4 O60664,P51151,O14964 3 +Activation of nmda receptors and postsynaptic events 0.2920618573005339 0.1922792306590587 0.8475234863806944 1.0 0.9676740579744758 26 P07196,P35609,Q13131,Q13555,P13861,P28482,Q15334,P49593,Q15418,P54619,P10644,O14936,P51812,Q14012,Q13885,Q14168,Q9BVA1,Q9BUF5,P63000,P68371,P17612,P16220,P27361,P52292 24 +Golgi cisternae pericentriolar stack reorganization 0.3322179080890619 0.1919842212777875 0.8477545651166074 1.0 0.9676740579744758 12 Q9H0U4,P06493,P61019 3 +Smad2 smad3 smad4 heterotrimer regulates transcription 0.3444393270804987 0.1789705809607502 0.8579608016985887 1.0 0.9769276339080176 5 P27361,P50750 2 +Piwi interacting rna pirna biogenesis 0.3409078094659648 0.177577511512129 0.8590547870350114 1.0 0.9773761065206812 10 Q8N2A8 1 +Tp53 regulates transcription of cell cycle genes 0.3006045463746871 0.1664509916908625 0.8678020480296018 1.0 0.9857755397391376 18 Q9Y3B8,Q07812,P06493,P24941 4 +Chaperone mediated autophagy 0.360275208029118 0.1663904750277523 0.8678496692975644 1.0 0.9857755397391376 7 P08670 1 +Antigen processing cross presentation 0.2671230082441866 0.1632434955879581 0.8703267209705001 1.0 0.9874014673430884 52 P28074,P04439,O00231,P10321,P01889,Q9UL46,O43242,Q9UBG0,P61289,Q9UIQ6,P28072 11 +Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.2879160856941195 0.1598404415042041 0.8730067659076353 1.0 0.9876154337172276 25 P22626,Q9UL46,O14979,P14174,P52597 5 +Hiv transcription initiation 0.3090418681959663 0.1574555778308294 0.8748858148808696 1.0 0.9889397551204 16 Q92804 1 +Golgi associated vesicle biogenesis 0.2799933161208834 0.1433355531276232 0.8860251783818736 1.0 0.9974928621137866 30 P55327,Q9H3P7,Q9Y5X3,P51809,O60749,P09496,O75976 7 +Aquaporin mediated transport 0.3558518518518552 0.1339902821699039 0.8934102588454753 1.0 1.0 6 Q9UBI6,P17612,P63218,P13861,P10644 5 +Gaba receptor activation 0.30538726147286 0.1322474185136352 0.8947885959126458 1.0 1.0 4 P63218 1 +Adp signalling through p2y purinoceptor 12 0.30538726147286 0.1322474185136352 0.8947885959126458 1.0 1.0 4 P63218 1 +Gaba b receptor activation 0.30538726147286 0.1322474185136352 0.8947885959126458 1.0 1.0 4 P63218 1 +Sema4d induced cell migration and growth cone collapse 0.3482513337285144 0.1274379245342408 0.8985938014856438 1.0 1.0 7 O75116,Q7Z406,P60660,P35580,Q13464,P61586 6 +Apc c cdc20 mediated degradation of cyclin b 0.3183669681331993 0.1216306193049594 0.9031915628210448 1.0 1.0 11 Q9UJX3,P30260,P06493 3 +Assembly and cell surface presentation of nmda receptors 0.3157828088039588 0.1211764595928679 0.9035512692249908 1.0 1.0 12 P07196 1 +Protein ubiquitination 0.2811168103939649 0.1142951362819882 0.909003837919709 1.0 1.0 25 Q9BUN8,O75381,Q14527,Q9GZS3 4 +Post translational protein modification 0.2297073273232657 0.1136800863368733 0.9094913989729968 1.0 1.0 414 Q15907,P24390,P21796,O43731,Q9BT22,P61289,Q92564,Q9BW61,P45880,P53634,P04439,P49257,P07910,Q99627,P33908,Q15363,Q9Y2G5,Q9H0U3,Q9BT78,Q86YN1,O43242,O95249,P49721,Q9GZS3,P10619,O60762,O60725,Q9Y2B2,Q9BTY2,P06493,O15027,Q96AA3,Q15293,P51151,P05067,Q96K76,Q9BUN8,Q9Y277,Q13438,P41208,P60604,Q9BTX1,O15504,P38435,O76024,Q9NR45,P28072,Q9BZG1,Q12907,P51148,P61020,Q07065,Q9NXR7,Q13263,P04066,O75935,Q5JRA6,O43292,Q9H0U4,Q15388,P07942,O60826,Q9UBV2,Q9GZP9,P28074,Q02818,O43852,O00231,Q92905,Q969Q5,P20339,Q9Y297,O43505,Q9BU89,Q10472,Q9BVK6,Q8NFH4,Q14527,P46977,P49755,Q8N1F7,O75381,P61978,O15498,Q13190,P16278,P61019,O60476,Q96PC5,Q9UL46,O43681,P04843 92 +Myogenesis 0.3487407407407442 0.1132204261826085 0.9098558020391878 1.0 1.0 6 P35221,P19022,P35222,O60271,P60953 5 +Fgfr1 mutant receptor activation 0.3271820208574559 0.0992522618700861 0.9209379806963098 1.0 1.0 9 O95684 1 +Orc1 removal from chromatin 0.2586982393935958 0.09386343347568 0.9252176414121402 1.0 1.0 53 P28074,Q9Y619,O00231,Q9UL46,P24941,O43242,P61289,Q14566,P33991,P28072 10 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.325281949961466 0.0929924433003971 0.9259095645819464 1.0 1.0 9 Q9UJX3,P30260 2 +Ra biosynthesis pathway 0.3163507109004693 0.0925880316966286 0.9262308522252798 1.0 1.0 5 Q9BTZ2,Q8NBN7,Q8TC12,Q9HBH5 4 +Mrna decay by 3 to 5 exoribonuclease 0.2991747227901715 0.0905268481415702 0.9278685598079296 1.0 1.0 15 Q969T7,Q13868,Q15024,Q9Y3B2,Q9GZS3 5 +Abc transporter disorders 0.2669567739574616 0.0880303209703024 0.9298525770344463 1.0 1.0 45 Q9UBV2,Q9GZP9,P28074,O00231,Q9UL46,O43242,Q9BUN8,P61289,P49721,P28072 10 +Interferon alpha beta signaling 0.3159680248189871 0.084455826116856 0.9326940229604894 1.0 1.0 10 P10321,P01889,P04439 3 +Negative feedback regulation of mapk pathway 0.2616250586740118 0.0838251445036975 0.9331954559510448 1.0 1.0 3 P27361 1 +P75 ntr receptor mediated signalling 0.2881543913095645 0.0577315246533236 0.9539624825225412 1.0 1.0 16 Q13501,Q92542,Q9NQC3,P78536 4 +Translation of sars cov 2 structural proteins 0.283677622771468 0.0550021851633672 0.9561367229214068 1.0 1.0 17 P46977,Q10472,P49841,P04843,Q9H0U3 5 +Signaling by fgfr 0.270996439878343 0.0501073113997009 0.96003687340459 1.0 1.0 26 O43251,P52272,P31483,P35269,P19388,Q01085,P31943,P27361,P52597 9 +Signaling by fgfr2 0.2709964398783429 0.0501073113997001 0.9600368734045904 1.0 1.0 26 O43251,P52272,P31483,P35269,P19388,Q01085,P31943,P27361,P52597 9 +Hedgehog ligand biogenesis 0.2621009628351926 0.0354711829830967 0.9717040245575546 1.0 1.0 43 Q9UBV2,Q9GZP9,P28074,O00231,Q9UL46,O43242,P61289,P78536,P49721,P28072 10 +G1 s specific transcription 0.2929670447226814 0.0308692815776687 0.9753737879925954 1.0 1.0 11 Q9Y619 1 +G alpha s signalling events 0.2900872269248241 0.0278720489079518 0.977764201519794 1.0 1.0 5 P63218 1 +Maturation of sars cov 1 spike protein 0.2656203731122233 0.0265545083757091 0.978815057508386 1.0 1.0 4 P27824,Q14697,P14314 3 +Ca dependent events 0.3058197818821573 0.0220641203959707 0.9823968072801954 1.0 1.0 8 Q13555,P13861,P16220,P28482 4 +Rhobtb gtpase cycle 0.2644839998919679 0.0207233030117195 0.9834663798950088 1.0 1.0 29 P62995,Q16543,P08670,Q9BT78,P38159,P07910 6 +Cilium assembly 0.2414212497891656 0.0110716885429965 0.9911662511267508 1.0 1.0 66 Q99996,Q9H6D7,Q15154,O94927,P06493,Q8NCM8,A6NIH7,Q9BV73,Q7Z4L5,Q15019,P41208,O43805,O43924,Q92973,Q13409,P62258,Q66GS9,O75935,Q10713,O95684 20 +Tnf signaling 0.3023343142265999 0.0067658011528267 0.9946017129041193 1.0 1.0 7 Q8TCT8,P78536 2 +Regulation of pten stability and activity 0.2585025431612153 0.0058936809789175 0.9952975501642785 1.0 1.0 43 P31749,P28074,O00231,P46934,P31751,Q9UL46,O43242,P61289,P28072 9 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..70111b8a3caaf4864da25763dda6f371b32f728c --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd22 mediated bcr regulation", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen degradation", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Dectin 2 family", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 activates ptk6 signaling", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythropoietin activates phosphoinositide 3 kinase pi3k", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Erythropoietin activates stat5", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 2 signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna editing c to u conversion", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Na cl dependent neurotransmitter transporters", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Ncam1 interactions", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of tcf dependent signaling by dvl interacting proteins", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to gluconeogenesis", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h2 nr1h3 regulate gene expression linked to triglyceride lipolysis in adipose", "Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis", "Nr1h2 nr1h3 regulate gene expression to limit cholesterol uptake", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O glycosylation of tsr domain containing proteins", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase 2 plateau phase", "Phase 3 rapid repolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 promotes hif1a stabilization", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of gene expression in beta cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Release of hh np from the secreting cell", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scavenging of heme from plasma", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by membrane tethered fusions of pdgfra or pdgfrb", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 hd domain mutants in cancer", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch1 t 7 9 notch1 m1580 k2555 translocation mutant", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Terminal pathway of complement", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc transporters"], "available_proteins": ["AAAS", "AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "APLP2", "APOBEC3C", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMC8", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3B", "ATG4B", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAT2", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRD8", "BSG", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1D", "C1QBP", "C1orf35", "C2CD5", "CAB39", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCDC8", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA5", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEP135", "CEP250", "CERS1", "CERS2", "CETN2", "CFL1", "CGN", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLINT1", "CLNS1A", "CLTA", "CLTC", "CLU", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "COG3", "COG7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ9", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREB1", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC22", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFTUD2", "EGFR", "EHD1", "EHHADH", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120B", "FAM3C", "FAM49B", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNBP1L", "FOXK1", "FOXK2", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FYTTD1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GUSB", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILK", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "IVD", "IWS1", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP2", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRPPRC", "LRRC1", "LRRC8C", "LRSAM1", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LYN", "LYPLA1", "LZTFL1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARC1", "MARCKS", "MARK3", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "METAP1", "MFAP1", "MFN1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINPP1", "MIOS", "MIPEP", "MLEC", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO1E", "MYO6", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCK1", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEU1", "NF2", "NFRKB", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "P3H1", "P3H3", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA5", "PDIA6", "PDK3", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PDZD11", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPO", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBFOX2", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "REL", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOX2", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SATB2", "SC5D", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGPL1", "SGTA", "SH3GL1", "SHC1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIKE1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35B2", "SLC38A2", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMG8", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", 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0.0012069994051919 0.5131533710185364 0.0141053263822435 52 O43674,Q9UDW1,P14406,P20674,O75438,O43676,O75306,P09669,P00403,P31749,Q9NX14,P21912,P54619,O95168,Q96J02,Q86Y39,O95298,Q9Y6M9,P13073,P14927,P31751,Q07812,O14949,P56556,O75489,P22695,P49841,P05198,P15954,P10606,O14548 31 +Proteoglycan biosynthesis 0.8744447734675714 2.9201783590374717 0.0034983110560886 0.8761456369331521 0.0285615532798471 4 Q9NX62,Q8NCH0,Q8TB61 3 +Sphingolipid metabolism in senescence 0.8162756632101629 2.9064407987042413 0.0036556606686679 0.8872707011402861 0.0289822010549121 12 P04062,O15269,P24941,Q96G23,Q16739,Q13510 6 +Leptininsulin signaling overlap 0.7380881917727171 2.9046009625273252 0.0036772158391105 0.8887149194441442 0.0289822010549121 2 P31749 1 +Autosomal recessive osteopetrosis pathways 0.7377922462266976 2.903029611619022 0.0036957169130424 0.8899397698930172 0.0289822010549121 2 P51798 1 +Bmp signaling in eyelid development 0.7315773897602875 2.869959973295245 0.0041052376205006 0.9138579495500584 0.0305840202727297 2 P27361 1 +Complement and coagulation cascades 0.7862696437465022 2.8173158932006466 0.0048426869679276 0.9446042642038542 0.0331751888837343 3 P10909 1 +Overview of nanoparticle effects 0.7842287603118944 2.8071882430061197 0.0049976027970024 0.949512980533711 0.0338255934491151 3 P09601 1 +Sphingolipid metabolism overview 0.8530836729080515 2.7111141946021897 0.0067057527409826 0.9818682193589786 0.0434416155828874 9 O95470,P27544,Q96G23,Q16739,Q13510 5 +Sphingolipid metabolism integrated pathway 0.8530836729080515 2.7111141946021897 0.0067057527409826 0.9818682193589786 0.0434416155828874 9 O95470,P27544,Q96G23,Q16739,Q13510 5 +Cellular proteostasis 0.8259491564363725 2.6965295523715587 0.007006618014308 0.9848634458686611 0.0449026272744901 4 O15212 1 +Sphingolipid pathway 0.8162828576588491 2.6742552413687735 0.0074895424548067 0.9886730113463752 0.0469298176565846 10 O95470,P04062,Q96G23,Q16739,Q13510 5 +Vitamin d metabolism 0.8205297165933134 2.671150915266406 0.007559165260121 0.989136826717852 0.0469298176565846 4 P04062 1 +Mitochondrial complex iv assembly 0.7533508653750761 2.660903564798192 0.0077931273769333 0.990560921149549 0.04758195931626 13 P13073,Q8N8Q8,P14406,P20674,P15954,Q9Y2R0,P09669,P00403 8 +Oxidation by cytochrome p450 0.8653604286306336 2.6362567263080954 0.0083826283702603 0.9933763206571112 0.049465807016586 5 Q16850,Q6UW02,O43169 3 +Transcription factors regulate mirnas related to cardiac hypertrophy 0.7409709887507272 2.5895058677091307 0.0096113784810984 0.9968365373345612 0.0555896625145776 3 P31749,P31751 2 +Mitochondrial complex iii assembly 0.7674242718980602 2.5755676902348976 0.0100075682722335 0.9975077177919968 0.0568048637166783 11 Q9UDW1,P22695,O14949 3 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.791516375472979 2.5339387022454383 0.0112788459679329 0.9988412216367772 0.0600195731865002 4 P09601 1 +Triacylglyceride synthesis 0.7226169330964958 2.4953725734456382 0.0125824938798697 0.9994721745871008 0.0646479857965722 3 O00116,Q9HCL2 2 +Serotonin and anxiety 0.6593666765315229 2.475490005391212 0.0133053485739882 0.999658859468706 0.0666385525218234 2 Q06787 1 +Cholesterol biosynthesis with skeletal dysplasias 0.8428028197551916 2.41715382821893 0.0156424049360104 0.999916990777697 0.0751844624343727 7 Q15125,Q16850,Q15392,O75845 4 +Metabolism of spingolipids in er and golgi apparatus 0.8094051631798964 2.383160278694066 0.0171647191572634 0.999966999552926 0.07955928791632 5 O95470,Q10472,Q16739 3 +Inclusion body myositis 0.7007794368232529 2.3819754114315033 0.0172200472167873 0.9999680884267944 0.07955928791632 3 P05067 1 +Tca cycle nutrient use and invasiveness of ovarian cancer 0.6980461811722912 2.367674650484434 0.017900269238815 0.9999788781078104 0.0813221642217458 3 P00533,P27361 2 +Acquired partial lipodystrophy barraquersimons syndrome 0.7567923901873855 2.366698637814891 0.0179475402905167 0.9999794754382328 0.0813221642217458 4 Q03252,O60725 2 +Glycerolipids and glycerophospholipids 0.8165157275879993 2.2982191703090433 0.0215493181526571 0.9999977027494052 0.0958462210371915 7 Q9UG56,Q9BVG9,Q86UL3,Q9HBU6,Q9HCL2 5 +Ferroptosis 0.5605742685234354 2.2463562557849337 0.0246811978944914 0.9999996600840334 0.1061155322498712 23 P48637,P45880,P16435,P09601,Q9Y277,Q96QD8,Q9UKU0 7 +Regulation of apoptosis by parathyroid hormonerelated protein 0.7796208530805664 2.2453071537459732 0.0247484211119666 0.9999996737649612 0.1061155322498712 5 Q07820,P31749,Q07812,Q9BXK5 4 +Kennedy pathway from sphingolipids 0.820148148148127 2.2100699979041636 0.0271003046825799 0.9999999226307902 0.1121651499362337 6 Q9UG56,O95470,Q9BVG9,P48651,Q9HBU6 5 +Oxidative phosphorylation 0.5052290711916322 2.1775704224522765 0.029438033579602 0.9999999815554506 0.1193542041730804 32 P56385,O95298,Q9Y6M9,P56556,O75489,O75964,O43674,P03886,P24539,O95168,P00846,P51970,O75438,P56134,P06576,O75306,Q86Y39,O75947 18 +Glycosaminoglycan degradation 0.7892708950800245 2.1732246602875738 0.0297634126220047 0.9999999848964845 0.1198580670453705 7 P07686,P15586,P06865,P08236,P16278,P54802 6 +Heme biosynthesis 0.7622908903001904 2.1640912456711434 0.0304573472521487 0.9999999901398372 0.121829389008595 5 P22830 1 +Nanomaterial induced apoptosis 0.7533465549873853 2.1218856588077624 0.0338473410366071 0.9999999987774432 0.131849772926914 5 O43464,O95831 2 +Il17 signaling pathway 0.6982528871779629 2.077227964955781 0.0377805239765858 0.9999999998925048 0.1425138752534503 4 P31749,P49841,P27361 3 +Hostpathogen interaction of human coronaviruses apoptosis 0.6956463305462106 2.064120181478589 0.0390063229283179 0.9999999999497152 0.1462123802847642 4 Q07820,P31749 2 +Deregulation of rab and rab effector genes in bladder cancer 0.583012725658485 2.0372342407246276 0.0416265740738872 0.9999999999901208 0.154095889118241 2 Q9BXI6 1 +Spinal cord injury 0.5367273541149089 2.019306051642876 0.0434554192915686 0.9999999999968354 0.1560206620347884 21 O75116,P62942,P27361,P24941,P08670,Q08722,Q9NQC3,P06493,P14174 9 +Reninangiotensinaldosterone system raas 0.6839934613783826 2.005296143186768 0.0449313969036506 0.9999999999987392 0.1603539673926694 4 P16220,P0DP25 2 +Degradation pathway of sphingolipids including diseases 0.7451520067633958 1.9671164097124376 0.0491697918568685 0.999999999999911 0.1734035263117967 7 P17900,O43681,P06865,P16278,P06280 5 +Amyotrophic lateral sclerosis als 0.6504496618824428 1.947892631686058 0.0514278116422608 0.9999999999999784 0.1783773884719227 11 P07196,P07197,P20339,Q9BUN8,Q07812 5 +Mirna regulation of p53 pathway in prostate cancer 0.672311399406473 1.945960350688701 0.0516595025405595 0.9999999999999812 0.1783773884719227 4 O14681 1 +7oxoc and 7betahc pathways 0.6711640948023861 1.9320411068175136 0.0533544323782226 0.9999999999999936 0.1817099525566898 10 O15118,P61916,Q15125 3 +Synaptic signaling pathways associated with autism spectrum disorder 0.615473012390281 1.8829033941667337 0.0597134611769798 1.0 0.1966255406711601 13 P31749,Q05086,Q15382,P49841,P31751,P54619,P27361 7 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.5831355033878516 1.836773339808768 0.0662433632035184 1.0 0.2088944151814655 15 O60725,P49841,P42167,O75844,P50402,P55209 6 +Ccl18 signaling pathway 0.6744849680299394 1.831516514376348 0.0670234850775266 1.0 0.2091413461057899 9 P07196,P00403,P08670 3 +Copper homeostasis 0.673200429348741 1.8248802925385557 0.0680190957841904 1.0 0.2108404341252346 9 P31749,O75880,P49841,P05067,P78536 5 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.4990377801711024 1.8120693139935256 0.0699754871167253 1.0 0.2138737965208629 24 Q9BWD1,Q15125,O75845,Q16850,Q15800,Q15392,Q14534 7 +Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.686435357794445 1.7843991437783933 0.0743588301124917 1.0 0.2238275896315409 8 P51148,P61020,P20339,O14964,P31943,P27361 6 +Omega3 omega6 fatty acid synthesis 0.7069459526906798 1.6935717530165604 0.090346689409809 1.0 0.2606434647858491 6 O15254 1 +Familial partial lipodystrophy fpld 0.6877982592491905 1.6926321963657245 0.0905254986756221 1.0 0.2606434647858491 7 O75844,Q03252,O60725,P31751 4 +Relationship between inflammation cox2 and egfr 0.6986666666666582 1.654784016740365 0.0979683172697285 1.0 0.2767256734253943 6 P31749,P00533,P31751,Q9H7Z7,P27361 5 +Caloric restriction and aging 0.6547359275048712 1.6441002629695454 0.1001554936606323 1.0 0.2802472968156661 5 P43490 1 +S1p receptor signal transduction 0.6541822778867392 1.6223414186033922 0.1047302648951662 1.0 0.2903220366396236 8 P31749,Q13510,P31751,Q9H0H5 4 +Apoptosis modulation and signaling 0.5783452782757335 1.598368357644986 0.1099610223930407 1.0 0.2992546545490971 12 Q9NR28,Q07820,Q07812,O95831,O43464 5 +Statin inhibition of cholesterol production 0.6820287610965461 1.5764737663787518 0.1149166599193294 1.0 0.3056314205154584 6 Q8WTV0 1 +Tgfbeta receptor signaling in skeletal dysplasias 0.599799341679904 1.570036594112885 0.1164065980822299 1.0 0.3056314205154584 4 P27361,P62942 2 +Tgfbeta receptor signaling 0.599799341679904 1.570036594112885 0.1164065980822299 1.0 0.3056314205154584 4 P27361,P62942 2 +Metapathway biotransformation phase i and ii 0.4722871587821444 1.5585298969180206 0.1191076865407694 1.0 0.3099920575471553 22 P48637,Q6UW02,Q99735,Q8NCH0,Q16850,Q7LGA3,P07099 7 +Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition 0.6369357747142357 1.555640989923584 0.1197934859033766 1.0 0.3104213808626631 5 P08670,P31749 2 +Neovascularisation processes 0.5917009731353527 1.5273259185008208 0.1266799875945135 1.0 0.3240397965936911 4 P31749,P27361 2 +Striated muscle contraction pathway 0.6510632037193648 1.5133500725303668 0.1301907599645715 1.0 0.3287868344867993 7 P09493,P08670 2 +Sars coronavirus and innate immunity 0.4933412252145682 1.4960747792083795 0.1346341694032931 1.0 0.3334148191290487 2 Q7Z434 1 +Mitochondrial complex i assembly model oxphos system 0.4309458850219688 1.4893927961385978 0.1363839644451723 1.0 0.3358877802038127 31 O43674,Q96CU9,O96000,O75438,O43676,O75306,Q8N183,Q9NX14,Q7L592,O95168,O95298,Q9Y6M9,Q9NPL8,Q9BUB7,P56556,Q8TB37,O75489,P03886,P51970 19 +Gdnfret signaling axis 0.5331557134399179 1.462470253500047 0.1436123900391857 1.0 0.3507909199317814 3 O94813,P35222 2 +Allograft rejection 0.6024262309277955 1.453330188433943 0.1461320993501365 1.0 0.3540436228157778 9 P08670,P08183,P10321,P01889 4 +Phosphodiesterases in neuronal function 0.5272978689145984 1.428994558517521 0.1530057974312326 1.0 0.3647658210760586 3 P16220 1 +Endothelin pathways 0.6207075358709228 1.3635619749366448 0.1727054665948346 1.0 0.3958940695789287 7 P00403 1 +Sarscov2 b117 variant antagonises innate immune activation 0.4708493637170842 1.3568305139793375 0.1748350695197689 1.0 0.3970042340162801 2 Q7Z434 1 +Adipogenesis 0.5166781194003824 1.347396497866957 0.1778525679234006 1.0 0.3970042340162801 14 P14174,O75844 2 +16p112 distal deletion syndrome 0.6085005489983806 1.3030112101272588 0.1925709344381339 1.0 0.4204112707880139 7 Q9H2V7 1 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.5175403554009508 1.2920693425168046 0.1963331317175634 1.0 0.4255074418315192 13 P13674,O75718,Q32P28 3 +Nocgmppkg mediated neuroprotection 0.5870712990910274 1.279029600332446 0.2008866324756193 1.0 0.4329751981908959 8 P07196,P30536 2 +Glutathione metabolism 0.5817039324347786 1.2780501006130556 0.2012317615752989 1.0 0.4329751981908959 5 O75874 1 +Regulation of wnt bcatenin signaling by small molecule compounds 0.6183836959690718 1.2732737672723493 0.2029209120543025 1.0 0.4350390776415982 6 P25054,O14641,P49841 3 +Vitamin d receptor pathway 0.5214139181032645 1.2599111325510843 0.2077014222877224 1.0 0.4430665664644765 12 P09493,Q96KA5,P24941 3 +Influence of laminopathies on wnt signaling 0.5290907230798396 1.2538397208718304 0.2099002684767934 1.0 0.4436497209019333 11 O60725,O75844 2 +Calcium regulation in cardiac cells 0.4180624244691477 1.1891477548733205 0.2343815291951347 1.0 0.4833612159179942 25 P16615,Q9UBI6,P62942,P20020,Q13555,P05026,P13861,P63218,P62258,Q9Y3B8,P54709,P0DP25 12 +Robo4 and vegf signaling pathways crosstalk 0.4424385912992081 1.179944441553411 0.2380223126867298 1.0 0.4874958706573573 2 O94813 1 +Regucalcin in proximal tubule epithelial kidney cells 0.5981415679703426 1.176075306190164 0.2395647846792772 1.0 0.488974697496059 6 P31749,Q8NE86,Q07812 3 +Nephrotic syndrome 0.4573069136004284 1.157310063428978 0.247145703474195 1.0 0.4993180992224416 17 Q14108 1 +Camkk2 pathway 0.4946626338066643 1.1510243794524109 0.2497222060009809 1.0 0.5028190364073806 13 P09601,Q13501,P16220,O76024 4 +Intracellular trafficking proteins involved in cmt neuropathy 0.5020743479824475 1.1437622384909707 0.252722254106652 1.0 0.5054445082133041 12 P07196,Q9NR77 2 +Riboflavin and coq disorders 0.5870194052944175 1.1226297102766989 0.2615947917730652 1.0 0.5133354299363764 6 Q8NI60 1 +Progeriaassociated lipodystrophy 0.5333059307114647 1.082671231375809 0.2789543777547236 1.0 0.532259998456109 9 O75844 1 +Erk pathway in huntingtons disease 0.5063727493541129 1.0723039328251631 0.2835835408998686 1.0 0.5373413461488943 4 P00533,P16220 2 +Vitamin b12 metabolism 0.530834660819798 1.0693786070996876 0.2848991029916956 1.0 0.5373413461488943 9 Q8WTV0 1 +Mitochondrial complex ii assembly 0.420538620893764 1.0435478683697446 0.2966946229513201 1.0 0.5491614760216981 2 P21912 1 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.5537762977423388 1.0306666471041794 0.3026971705136816 1.0 0.5548964526668279 7 P31749,Q15382,P49841 3 +Endometrial cancer 0.4560367204254142 1.018618182323183 0.3083842688400322 1.0 0.5620704104851963 15 P31749,P25054,P35222,P00533,P49841,P31751,Q07812,P27361 8 +Vitamin a and carotenoid metabolism 0.5635091772741545 1.0097824602652232 0.3125995252568252 1.0 0.5645736880395994 6 Q8WTV0 1 +Vasopressinregulated water reabsorption 0.4211303063213488 0.9732388778489612 0.3304345924892065 1.0 0.5861280271534735 18 Q15907,P51148,P61020,P20339,P16220,Q8NCM8,Q9UJW0 7 +Tyrobp causal network in microglia 0.5150651550719231 0.9410789316025312 0.3466644113634434 1.0 0.6059002615032618 5 P61916 1 +Dopamine metabolism 0.4021899970405529 0.9298597359788676 0.3524437124801283 1.0 0.6106292227853385 2 P21964 1 +Mecp2 and associated rett syndrome 0.3897362711662294 0.9245950397401091 0.3551765941807345 1.0 0.6121319274328486 23 P31749,Q05086,P67809,P31943,P35637,P52597 6 +Cytosine methylation 0.5113201183604359 0.9222613935989624 0.356392246340937 1.0 0.6121319274328486 5 P48735 1 +Aryl hydrocarbon receptor pathway wp2873 0.526139184452895 0.8937262734923771 0.3714683643543162 1.0 0.6289634805544672 7 Q07812,Q16543,O00170 3 +1q211 copy number variation syndrome 0.482203301972597 0.8886818759412789 0.3741740742317079 1.0 0.6317499950201074 10 Q9NPH0 1 +Ebola virus infection in host 0.3496534570246623 0.879399307436302 0.3791848075041857 1.0 0.6366032261197033 43 P31749,O15118,P04439,P09496,P07858,P10321,P01889,P46934,P20339,P51151,P05198,P61916,Q9P253,P78536,O75569 15 +Ciliary landscape 0.2863684277600084 0.8299913093570331 0.4065436972674827 1.0 0.6693371369376235 108 P10619,P07196,O15173,Q15024,Q92905,P27105,P09669,P16278,Q13445,P61019,Q13868,O95721,O43805,Q99627,P08670,Q9BT78,Q14566,O43464,P33991,Q15555,P07197,Q96PK6,P06280 23 +Nad metabolism 0.4602547954081213 0.8274878757922195 0.4079605912291573 1.0 0.6695505394417628 4 P43490 1 +Glycerophospholipid biosynthetic pathway 0.4987325165995441 0.8238170204041447 0.4100435350608111 1.0 0.6695505394417628 8 Q86UL3,O95674,P48651,Q9HCL2 4 +Wntbetacatenin signaling pathway in leukemia 0.5206452476470133 0.8058839581380695 0.4203097617753943 1.0 0.6788743035721817 6 P31749,P25054,P49841 3 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.4162059666491006 0.7927066217177212 0.427948771445314 1.0 0.6871931897009727 3 Q15758 1 +Alzheimers disease and mirna effects 0.2993908198975283 0.7910424177187904 0.4289192392093319 1.0 0.6871931897009727 88 P28074,P20618,P21796,P16615,P33176,P31749,P45880,P12236,O95197,P05067,Q9Y277,P0DP25,P31751,Q9NQC3,P28072,P12235,Q92542,Q9H0B6,Q8NE86,P49841,P05198,O43242,P78536,P49721,Q96IX5,P27361 26 +Aryl hydrocarbon receptor pathway wp2586 0.4954010063977758 0.743422987426455 0.4572256312767564 1.0 0.7133677388506461 7 P00533,Q16543,O00170,P24941 4 +Bile acids synthesis and enterohepatic circulation 0.4412200177672344 0.7283939102174638 0.4663724900379191 1.0 0.7225548943428877 4 P51114,P27361,P28482 3 +Complement system in neuronal development and plasticity 0.4234937504553643 0.7142962736188129 0.4750439959733943 1.0 0.729316889053538 13 O43464,Q9NR28,Q8N3R9 3 +Ketogenesis and ketolysis 0.4679354255125124 0.7072511928968193 0.4794103903254862 1.0 0.7307636640255494 5 O43772,P23786,P53985 3 +Extracellular vesiclemediated signaling in recipient cells 0.4976918171700999 0.69878038949341 0.4846892858288953 1.0 0.7350504182036175 6 P31749,P25054,P00533 3 +Wnt signaling in kidney disease 0.3949082297217375 0.67459602074158 0.499932461841218 1.0 0.7382451041053562 3 O14641,P35222 2 +Development of ureteric collection system 0.429671305892795 0.669205628800288 0.5033643161253865 1.0 0.7382451041053562 4 P05556,O94813,P35222 3 +Type i interferon induction and signaling during sarscov2 infection 0.3937240970988926 0.6681225179658005 0.5040553890691628 1.0 0.7382451041053562 3 P42224,Q7Z434 2 +Alzheimers disease 0.2921649677123759 0.6667356542076465 0.5049410002426833 1.0 0.7382451041053562 87 P28074,P20618,P21796,P16615,P33176,P31749,P45880,P12236,O95197,P05067,Q9Y277,P0DP25,P31751,Q9NQC3,P28072,P12235,Q92542,Q9H0B6,Q8NE86,P49841,P05198,O43242,P78536,P49721,P27361 25 +Endochondral ossification with skeletal dysplasias 0.4540697186498457 0.6621842049707484 0.5078531756429463 1.0 0.7382451041053562 9 Q96QD8,P22413 2 +Endochondral ossification 0.4540697186498457 0.6621842049707484 0.5078531756429463 1.0 0.7382451041053562 9 Q96QD8,P22413 2 +15q112 copy number variation syndrome 0.4275984601717379 0.6586722314639288 0.5101062682714512 1.0 0.7397161457172383 4 Q96CW5,Q9BSJ2,Q06787 3 +Cholesterol biosynthesis pathway 0.4185457469105239 0.646859247622324 0.5177230429321764 1.0 0.7489391591931484 12 Q14534,Q16850,Q15800 3 +Cerebral organic acidurias including diseases 0.4512222091181224 0.6266646074330795 0.5308791083464655 1.0 0.7642607453490179 5 Q9H9P8 1 +G1 to s cell cycle control 0.345406704506475 0.6201989910823027 0.5351267856748416 1.0 0.7683867033208741 27 Q9Y619,P16220,P24941,P06493,Q14566,P33991 6 +Acute viral myocarditis 0.3958737416699812 0.5878035243833458 0.556664178142426 1.0 0.7918182581691787 14 P31749,P49841,P16220,Q07812,Q9NRG0,P27361 6 +Follicle stimulating hormone fsh signaling pathway 0.4239456072366594 0.5715414705418932 0.5676326574024817 1.0 0.7999831769714729 10 P31749,P49815,Q15382,P16220,P27361 5 +Serotonin receptor 467 and nr3c signaling 0.4100215599348026 0.5706584126682762 0.5682312144238761 1.0 0.7999831769714729 4 P27361,P16220 2 +Wnt signaling pathway 0.3875631891462153 0.5378118562204094 0.590706945836112 1.0 0.820655803539214 14 P31749,P25054,O14641,P49815,P35222,P49841,Q9BTU6 7 +Il7 signaling pathway 0.4552467104574064 0.5078758079476818 0.6115404415130559 1.0 0.8417508155699337 6 P31749,P49841,P27361 3 +Apoptosis 0.3979624294269491 0.5005647620266164 0.6166774673596349 1.0 0.843297865720107 11 Q07820,P31749,Q9NR28 3 +Hepatitis b infection 0.3356172142378089 0.4982970934589553 0.6182746561881138 1.0 0.843297865720107 23 P31749,P31751,Q9Y277,Q07812,O00571 5 +Ras and bradykinin pathways in covid19 0.3950251702694609 0.4977614977445662 0.6186521566004612 1.0 0.843297865720107 4 Q99829,Q13464,P28482 3 +Cell migration and invasion through p75ntr 0.4232504132489098 0.4962202356476443 0.6197390355459846 1.0 0.843297865720107 5 P31751 1 +Small cell lung cancer 0.383131613838609 0.4772906077913568 0.6331551980914014 1.0 0.8539762083008903 13 P31749,Q07812,P31751,P24941 4 +P53 transcriptional gene network 0.4205321072340036 0.4418916529030652 0.6585676111484502 1.0 0.8767746342443999 8 Q07812,P04066 2 +Regulatory circuits of the stat3 signaling pathway 0.3859217814109571 0.4365096275482698 0.6624670155947014 1.0 0.8786618062228799 11 P16949,Q13263,P00533,Q8WTS6,P27361 5 +Melanoma 0.357340505086084 0.4319633607316618 0.6657680428134709 1.0 0.8786618062228799 16 P31749,P16220,P31751,Q07812,P27361,P0DP25 6 +Cardiac progenitor differentiation 0.3484310242747124 0.4314005365151037 0.6661771598783377 1.0 0.8786618062228799 3 P13591,P49841 2 +Envelope proteins and their potential roles in edmd physiopathology 0.3501551001647103 0.4285169179841117 0.6682748190675856 1.0 0.8792313292809735 17 P33176,O94901,Q9BTV4,Q14739,P42167,Q8WXH0,P50402,P27361,P28482 9 +Mitochondrial immune response to sarscov2 0.4064651842940406 0.4252718611064531 0.670638503865463 1.0 0.8803976834885814 9 Q9Y6M9,Q99623,Q86UT6,Q9BQ95 4 +Eicosanoid synthesis 0.3148860609647907 0.4205813262642543 0.6740608319898196 1.0 0.8810093330393256 2 Q9H7Z7 1 +Pi3kaktmtor vitd3 signaling 0.4321517697130987 0.4098145674249538 0.6819419792511565 1.0 0.8860443832397051 6 P31749,P49841 2 +Myometrial relaxation and contraction pathways 0.3234246529708379 0.3979213650774229 0.6906881506790792 1.0 0.8884674720928125 21 P16615,Q9Y3B8,P63218,P16220,P0DP25 5 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.3897185704229231 0.3971011481277824 0.6912928733163921 1.0 0.8884674720928125 10 P31749,P35222,P49841,P31751,P27361 5 +Kisspeptinkisspeptin receptor system in the ovary 0.4261273783451875 0.3851170441516477 0.7001507007071828 1.0 0.8911782139811947 6 P31749,P31751 2 +T cell receptor and costimulatory signaling 0.397679523161779 0.3835938477610511 0.7012795005992958 1.0 0.8911782139811947 5 P31749 1 +Nrp1triggered signaling pathways in pancreatic cancer 0.3698264826494583 0.3764799615861497 0.7065601099165209 1.0 0.8919353711749021 12 P31751,P24941 2 +Disruption of postsynaptic signaling by cnv 0.3953060111657663 0.3730934321736083 0.7090789067170842 1.0 0.8919353711749021 9 Q13555,Q06787,P28482,P27361,Q14168 5 +Map3k1 role in promoting and blocking gonadal determination 0.3951421800947747 0.3728451101797101 0.7092637266236719 1.0 0.8919353711749021 5 Q13464,P49841,P35222,P28482 4 +Tnfalpha signaling pathway 0.3194199182556879 0.36937810615105 0.7118459147006038 1.0 0.8919353711749021 21 Q9Y297,P31749,Q9NR28,Q16543 4 +Mfap5mediated ovarian cancer cell motility and invasiveness 0.3653048113561178 0.3611757595843041 0.7179680618676774 1.0 0.8970837838011231 4 P27361,P16220 2 +Preimplantation embryo 0.4071581528523795 0.3425788510821033 0.7319153147069233 1.0 0.9015915682375564 7 Q99729,P05023 2 +Genes related to primary cilium development based on crispr 0.3481215436910961 0.3417025341327935 0.7325747648242005 1.0 0.9015915682375564 15 Q8WXW3,Q7Z4L5,Q10713,O95684 4 +Embryonic stem cell pluripotency pathways 0.3584781100338626 0.3415880249195467 0.7326609504304753 1.0 0.9015915682375564 13 P31749,P25054,O14641,P35222,P00533,P49841,P31751 7 +Circadian rhythm genes 0.2912438664050868 0.3376225363835637 0.7356476568668633 1.0 0.9015915682375564 47 O75116,P00813,P50416,Q05086,Q9BWF3,P49841,Q8WXF1,Q14103,P16220,Q9Y297,P23246,P43490,Q15233,P54802 14 +Proteasome degradation 0.2935392980340402 0.310928673946397 0.7558548454843086 1.0 0.9091415933208296 42 P28074,P04439,O00231,P10321,P01889,P46934,Q9UL46,O43242,P04843,P61289,P28072 11 +Nad biosynthetic pathways 0.3776365754619142 0.3011420072488973 0.7633062097141288 1.0 0.9091415933208296 5 P43490 1 +Cardiac hypertrophic response 0.3471718731698955 0.2826884650561311 0.7774156592944637 1.0 0.9138850748313616 13 P31749,P49841,P50750,P31751 4 +Primary focal segmental glomerulosclerosis fsgs 0.3064862370790444 0.279581629038772 0.7797985031465262 1.0 0.9148817084160032 21 P08670,Q14108 2 +Ppar signaling pathway 0.304368744880087 0.2652694105414441 0.7908019274725737 1.0 0.9169609898320116 21 O15254,Q9UKU0 2 +Liver x receptor pathway 0.279076649896428 0.2464585591607561 0.805327280162496 1.0 0.9241881013961244 2 O00767 1 +Proximal tubule transport 0.3656597408403184 0.2432592916021525 0.8078045378952379 1.0 0.9241881013961244 9 P08183,P05023 2 +Prion disease pathway 0.359134045077094 0.2166903738080902 0.8284496503663721 1.0 0.938699603837182 9 O60216,P30101,P16220,P49711,P14625,Q9UQE7,P27361,P28482 8 +Apoptosisrelated network due to altered notch3 in ovarian cancer 0.3220573274173058 0.2004034077338523 0.8411650945634617 1.0 0.9471134534505152 15 P08670,P31749,P05067 3 +Head and neck squamous cell carcinoma 0.2984684202077787 0.1874125011815195 0.8513372217317317 1.0 0.9548056229304172 19 P31749,P49815,P62942,Q15382,P00533,P31751 6 +4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.3583741424383826 0.1836792782268818 0.8542650658943169 1.0 0.9548056229304172 8 P31749,P27361 2 +Retinoblastoma gene in cancer 0.2694814319923906 0.1266740421298775 0.8991983916827195 1.0 0.9929077317384296 47 P16949,Q16204,Q9Y619,P24941,P33991,Q14527 6 +Notch signaling pathway 0.3125373756743542 0.1196421053312397 0.9047666640332744 1.0 0.9949094681989514 13 P31749,Q92542,P49841,P78536,Q96J02,Q13642 6 +Cannabinoid receptor signaling 0.3487407407407438 0.1132204261826074 0.9098558020391888 1.0 0.9968273125282298 6 P17612,Q8NCG7,P10644,P27361,P28482 5 +Physiological and pathological hypertrophy of the heart 0.3487407407407433 0.1132204261826063 0.9098558020391896 1.0 0.9968273125282298 6 Q08209,Q9P2K5,P28482,P63000,P61586 5 +Resistin as a regulator of inflammation 0.3427882838009345 0.1106977031313458 0.9118560674225672 1.0 0.9971857177685324 7 P31749,P31751 2 +Serotonin receptor 2 and elksrfgata4 signaling 0.2616250586740118 0.0838251445036975 0.9331954559510448 1.0 1.0 3 P27361 1 +Mirnas involved in dna damage response 0.2890139176784061 0.083773628134927 0.933236415995909 1.0 1.0 4 P04637,P16220,P16104 3 +Joubert syndrome 0.2774962003934714 0.0695314154998957 0.9445666272043314 1.0 1.0 19 P41208,Q10713,Q15382,Q8WXW3 4 +Onecarbon metabolism and related pathways 0.2997108503417926 0.0672964501182825 0.9463457028795326 1.0 1.0 13 Q9HBU6 1 +Il9 signaling pathway 0.3288270764558459 0.0604068723856718 0.951831585282755 1.0 1.0 6 P27361,P50750 2 +Hedgehog signaling pathway wp4249 0.3235555555555586 0.0477877753744651 0.9618853792641118 1.0 1.0 6 P17612,P98164,P48729,Q9Y496,Q2M1P5 5 +Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.3206799729939615 0.0411489291390246 0.9671771677989498 1.0 1.0 6 P06753,P18031 2 +Oxidative damage response 0.2917654028435968 0.031525150444532 0.9748507349560702 1.0 1.0 5 O95429,O95551,P60953,P12004 4 +Methionine de novo and salvage pathway 0.3059136847477582 0.0144922561668183 0.9884372572998268 1.0 1.0 7 Q9BV57 1 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a2b66a9a77ced6df17ca0af007822d3bac0cf800 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgf23 signaling in hypophosphatemic rickets and related disorders", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between loxl4 and oxidative stress pathway", "Interactions of natural killer cells in pancreatic cancer", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanomaterialinduced inflammasome activation", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 altering angiogenesis via nrp1", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAR2", "AARS", "AASS", "ABAT", "ABCB1", "ABCC1", "ABCD3", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAM9", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANXA1", "ANXA2", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APBB1", "APC", "APEX1", "APLP2", "APMAP", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL8B", "ARMC8", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG9A", "ATIC", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AURKB", "BAG4", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BLM", "BLVRA", "BPTF", "BRCA1", "BRD4", "BRIX1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "C1QBP", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPZB", "CARM1", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC6", "CDC73", "CDCA5", "CDCA7L", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CEP170", "CEP250", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHKA", "CHMP5", "CHMP6", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIP2A", "CISD1", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLPTM1L", "CLTA", "CLTC", "CLU", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT10", "CNOT9", "CNP", "COA3", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COQ8B", "COQ9", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CREB1", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCP1A", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DECR1", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLG1", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB4", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DPF2", "DPM1", "DPYSL2", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EGFR", "EHD1", "EHHADH", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMD", "EML4", "ENAH", "ENO1", "ENO2", "ENPP1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ESD", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC2", "EXOSC4", "EXOSC7", "EXOSC9", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAPDH", "GART", "GBA", "GCC2", "GCDH", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GIGYF2", "GLA", "GLB1", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNG12", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPS1", "GRB2", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2I", "GTPBP4", "GUSB", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIRA", "HIRIP3", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP3", "ILF2", "ILK", "IMP3", "IMPAD1", "IMPDH2", "INF2", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITCH", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA4", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LAMTOR3", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP2", "LPGAT1", "LRP1", "LRP2", "LRPPRC", "LRRC59", "LRRC8C", "LRRFIP2", "LRSAM1", "LRWD1", "LSM2", "LSM7", "LSS", "LTA4H", "LUC7L", "LUZP1", "LYN", "LZTFL1", "MACF1", "MAD2L1", "MAGED1", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MEPCE", "MFAP1", "MGST1", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPG", "MPI", "MPP1", "MPP2", "MPP5", "MPST", "MRE11", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO1E", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAM1", "NCAPG", "NCBP1", "NCDN", "NCK1", "NCK2", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEU1", "NF2", "NFRKB", "NIPBL", "NKRF", "NLRX1", "NME1", "NME2", "NME3", "NME7", "NONO", "NOP2", "NPC1", "NPC2", "NRP1", "NSD1", "NSDHL", "NSF", "NT5C3A", "NTHL1", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "ORC2", "ORC3", "ORC5", "OTUD7B", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", 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file mode 100644 index 0000000000000000000000000000000000000000..46b6696541a3a5517cb2627aacb233cc743bcaf9 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +er 40 91 4.784984933343095 1.710001596322286e-06 29.17233009708738 87.61893203883496 1.3358083950399515 0.3757472714196316 13.465054065187209 8.223393744963309 2.0429537263872786 0.4010648005920765 3.352239066712456e-07 0.030580517896993 0.0004487218378413 1.5938843806800965e-06 5.802962040612897e-16 +vesicles 52 183 3.64717982360989 0.0002651343772521 42.101941747572816 169.6626213592233 0.6789633151163722 0.6006686966705359 14.133870910307197 18.74575061031192 1.1351302778834993 0.3922666308151308 0.0009893608559754 0.2299069813709643 0.0062404955991049 0.0006849410113414 9.00135109828717e-08 +mitochondria 6 10 2.775483499070809 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--git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c41c5f0bcf3307c7b806bbf1e8db3b931a454caa --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..742418801b6832870dea3c378e685ac3bce7057f --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +er 0.6082973135625624 4.784984933343095 1.710001596322286e-06 2.906962946255351e-05 2.9070027137495855e-05 91 Q9H6H4,Q00765,Q15125,O15173,Q13190,P48651,O15269,Q16850,Q86Y07,Q969Q5,P51572,P61019,O00264,Q14739,Q15041,Q9NPA0,Q86UL3,O95674,Q8NHH9,Q9Y487,Q9BVG9,Q15363,Q9NQC3,Q9NR31,Q15392,Q96A33,P46977,Q9P2W9,O95470,P49755,Q07065,Q9Y5M8,Q96N66,O60499,O75845,O75915,P04843,Q12981,O96005,Q9Y3E0 40 +vesicles 0.4439218558309982 3.64717982360989 0.0002651343772521 0.0044977367869715 0.0022536422066434 183 Q15907,Q13277,Q9H6H4,P05023,Q15125,O15173,O15269,Q567U6,Q96L92,P61019,P31749,Q9H2V7,O43633,O00264,P04439,P20339,Q86UL3,P51798,P11279,O60476,O95674,P49257,Q8IY95,Q8IZA0,O60749,P09496,O43752,O15126,P53985,Q8IXU6,Q5VW38,P31751,Q93050,Q15363,Q9Y5X3,P13473,Q15392,O95470,P49755,P61020,O15400,Q13501,P30825,O60499,O43808,O75845,Q10713,O95249,O96005,Q9Y3E0,O15127,O15258 52 +mitochondria 0.8370615115123418 2.7754834990708095 0.0055119696297922 0.0896832671800415 0.0234258709266171 10 P45880,P21796,Q9Y277,Q969Q5,Q9NR31,Q15388 6 +golgi 0.4407416747477899 2.2873382374861575 0.0221760882535668 0.3169836399327934 0.0753987000621273 60 Q15907,P49755,Q8IXU6,O15258,P61019,Q13190,Q5VW38,O15127,Q9NR31,P09496,Q9Y3E0,Q9Y487,O15126,Q8IZA0 14 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b5d6c8f86466b18da1ddfb1107e83763e4371767 --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AHCY", "AHSA1", "AKAP12", "AKAP13", "AKAP8L", "AKR1A1", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH9A1", "ALG2", "ANAPC16", "ANAPC2", "ANKRD17", "ANXA11", "AP2B1", "AP2S1", "APC", "APLP2", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", 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0.2677048300346334 0.0230436364337774 0.0020640692536444 0.0017009652209114 0.0087768454005906 0.1139666614243892 +SNARE protein 8 12 2.5932894325562548 0.0095062731404742 4.660194174757281 11.12378640776699 0.9288896561072936 0.3201954718639376 2.5506648592929815 2.745113440103806 1.1546709449924732 0.3042666981599379 0.0114133203420679 1.0 0.031964215627013 0.0048864602536943 0.000378511976274 +serine protease 7 17 2.586053839692249 0.0097081764835778 5.662621359223301 17.516990291262136 1.1445634795625386 0.1820139001244477 2.0809494011218104 1.6626107291843584 1.568325484830445 0.2384821649427795 0.000110960195233 0.2107016729382093 0.0118453859760714 1.964483782727492e-05 0.000510790199304 +amino acid transporter 4 5 2.405502048773575 0.0161502614006683 1.9951456310679612 4.257281553398058 0.7191216814048915 0.3104355279029646 1.1762106872211882 0.8905220397339731 1.285467922271347 0.3110567625654792 0.0039714533726283 1.0 1.0 0.001983278822638 0.00138858926748 +transmembrane signal receptor 5 7 2.295987849613367 0.0216765761112158 3.266990291262136 7.169902912621359 1.6693846681257831 0.1085289610325799 1.5770125590990791 1.7927217985188668 1.0928815816574815 0.16461969248918 0.5423907673660513 0.0720814043883259 0.2246728541934789 0.3835116962454471 0.4658609742937001 +secondary carrier transporter 10 14 2.2303542480288683 0.0257239344025383 6.104368932038835 14.6626213592233 1.264699085385324 0.2718921136589474 3.483843477892234 2.781747184831951 1.2916784116683784 0.322278600042778 0.0673307238551385 0.290515894493261 0.5010041483550427 0.092069152986564 0.2628532947407447 +oxidoreductase 8 48 2.1955567340245143 0.0281236859121654 12.558252427184469 43.60436893203884 0.9664652969079414 0.3656199292680728 5.072676172192643 3.8442089013841825 1.3118377214144643 0.3470065139863294 0.0025569078412836 0.0105938135914028 0.000311534568034 0.0004619430126077 0.0062528183336539 +oxygenase 5 7 2.162919334654684 0.0305473843992221 3.138349514563106 6.771844660194175 1.5409868347565758 0.1477866581414416 1.2914149665013366 1.041089559555361 1.2379399582807478 0.2357869798067575 0.0057593610144797 0.0058373227860703 0.0224191931510111 0.0024022577840735 0.0008169542553505 +transfer/carrier protein 7 11 2.133024048108558 0.0329227535165528 4.33252427184466 11.024271844660197 0.5751131114698911 0.3717158985009051 2.2946984989028927 1.3525930522279908 1.248808855129494 0.3186564966906889 0.0362941385189957 1.0 1.0 0.0193169154759243 0.0271057364081029 +mitochondrial carrier protein 3 6 2.10530274516001 0.0352649633149424 3.2936893203883497 7.065533980582524 1.4583792806536486 0.1840967072966826 2.0141872967986307 1.116111686789906 1.1161599809390137 0.2507152229846449 0.0065763731833925 0.0607401038440192 0.1191939669275513 0.0379575415698398 0.0027834726260547 +calmodulin-related 7 15 1.9849932376520156 0.0471452238683574 5.053398058252427 12.385922330097088 1.3935892727836532 0.1814075830019033 2.0222219603900085 1.786979844553702 1.206053991839631 0.2252292235861566 0.0008580969592524 0.1135912525516411 0.2166826538338764 0.0215683584236732 0.0001380877092489 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f06c7ae5b5fbb660a1f5deeadcab10e460a8c764 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 163, + "title": "Average number of proteins per term", + "value": 14.012269938650308 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d0567228d4395df5f1703f61152a288efdc1a50e --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..23b28da900fd061718fdf7aabce19953e8f958be --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,49 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +voltage-gated ion channel 0.9478981645944308 3.581339209087271 0.0003418374907002 0.0542046229565545 0.006964938873018 3 P45880,P21796 2 +primary active transporter 0.7302643125083338 3.4882491414208223 0.0004861948133845 0.0762086331040474 0.0079249754581677 25 P16615,Q9NS69,Q9GZP9,P05023,Q96NB2,P05026,O96008,P98194,Q9H9B4,O60888,Q9BUN8,O75381,Q6P4A7,Q9Y5J7,Q15388,Q8N4H5 16 +aspartic protease 0.893494199184181 3.3322173589533284 0.0008615693638249 0.1310731536439621 0.0110303209797928 3 Q8TCT9 1 +galactosidase 0.879218472468918 3.265544141084466 0.0010925397589927 0.1632093284884386 0.011872265381054 3 Q8IW92,P06280 2 +G-protein coupled receptor 0.8617525162818225 3.183208426564211 0.0014565272665258 0.2114717237876373 0.0127380277516445 3 Q9NPR9,Q5VW38 2 +major histocompatibility complex protein 0.8374777975133186 3.0673504806201164 0.0021596547415498 0.2970042241263109 0.0162281241560415 3 P10321,P01889 2 +extracellular matrix glycoprotein 0.7608759988162207 3.0246784278049264 0.0024889760975523 0.3338289675361788 0.0162281241560415 2 Q32P28 1 +transporter 0.5142010915765355 3.0065109842616957 0.0026426450595216 0.3503498622480615 0.0165673517193085 58 O60830,Q92544,Q99595,Q9HD45,Q9H2D1,Q9H2V7,Q9NR77,O43615,P53985,Q92973,Q8NFH4,Q99808,Q9Y619,Q8N8Q8,P54105,Q99805,O43681,Q8N1F7,Q567V2 19 +protein modifying enzyme 0.6290614638277089 2.984496283123232 0.0028404565236466 0.3710183644300697 0.0171479412353481 29 P13674,P50897,O60725,O75718,Q86YN1,O15460,P33908,Q92791,Q6P2P2,O60476,Q9UMR5 11 +ATP synthase 0.6652989886601133 2.910357657033548 0.0036101536966299 0.4454064758987937 0.0196151684183562 21 P36542,P24539,P61421,Q93050,P00846,P56134,P06576,Q96IX5,O75964,Q9Y487 10 +membrane trafficking regulatory protein 0.6684779171846676 2.8997798784429265 0.0037342479987554 0.4565522681450472 0.0196349168966818 20 O43731,Q8WTV0,P24390,Q14108 4 +decarboxylase 0.8198105961228647 2.667777443954408 0.0076354817935961 0.7133115967006165 0.031912398265543 4 P14174,Q8NBZ7 2 +SNARE protein 0.756083366077149 2.5932894325562548 0.0095062731404742 0.7892187948221391 0.034400712322243 12 Q9P2W9,Q13277,O95721,O15400,Q13190,O60499,O95249,O43752 8 +serine protease 0.6745092794105153 2.586053839692249 0.0097081764835778 0.7961078525657614 0.034400712322243 17 P10619,P67812,P42785,Q9HB40,O43464,O14773,Q8N2K0 7 +amino acid transporter 0.8142772511848291 2.405502048773575 0.0161502614006683 0.9296295618988673 0.0506248578520949 5 Q96QD8,O75915,O14925,P30825 4 +transmembrane signal receptor 0.8160259890796604 2.295987849613367 0.0216765761112158 0.9719043126072492 0.063094319752289 7 O00264,O15173,Q9UMX5,Q8WUJ1,Q99720 5 +secondary carrier transporter 0.6616937199139075 2.2303542480288683 0.0257239344025383 0.985705417175296 0.0710678187731145 14 Q02978,Q8TB61,Q9BQT8,Q9Y6M7,O95202,Q9UBX3,Q9H936,Q9Y289,O75746,P55011 10 +oxidoreductase 0.4679414166376198 2.1955567340245143 0.0281236859121654 0.9904370329041196 0.0727644572013168 48 O43169,Q8N0U8,O15254,O95831,O43676,Q86Y39,O14949,P00403 8 +viral or transposable element protein 0.6638586605887914 2.1867734044472056 0.0287590699012918 0.9914039859261315 0.0732457561548526 3 Q9NUD5 1 +oxygenase 0.7870415913140073 2.1629193346546836 0.0305473843992221 0.9936344837018578 0.0754427826829273 7 Q6UW02,P09601,P30519,Q16850,Q14534 5 +transfer/carrier protein 0.684110164221409 2.133024048108558 0.0329227535165528 0.9957325352775254 0.0777740409159146 11 P12236,Q9Y5M8,Q5T8D3,O14828,P17900,O15127,O15126 7 +mitochondrial carrier protein 0.7966946377063665 2.10530274516001 0.0352649633149424 0.9971258306343576 0.0821169860047945 6 Q70HW3,Q9BSK2,Q9Y6C9 3 +primase 0.5912992009470317 2.085853925635005 0.0369918569238958 0.9978537347440848 0.0837454538693753 2 P49643 1 +calmodulin-related 0.6070253963100952 1.9849932376520152 0.0471452238683574 0.9996186229314324 0.1024622865405634 15 Q14257,O43852,Q8IYU8,Q9BPX6,P80303,P41208,P0DP25 7 +oxidase 0.5753078698101702 1.9575181984428616 0.0502865743130829 0.999777366697168 0.1078514685925331 17 P13073,O75880,P36551,P14406,P20674,O75845,P15954,Q15800,Q6ZRP7 9 +tight junction 0.558745190884884 1.8934105654988864 0.0583032914586545 0.9999440884476168 0.1202966646551986 2 Q07157 1 +phospholipase 0.7441875694121471 1.8664337078085351 0.0619807108005296 0.9999704526607196 0.1247362743956162 6 Q8NHP8,Q8IV08 2 +glycosyltransferase 0.502973228270788 1.816559105924624 0.0692846499238193 0.9999917367498388 0.1360650353925608 23 P46977,O60762,Q8TCJ2,Q10472,Q8NBN7,Q68CQ7,Q9BT22,Q16739,Q9Y2G5,Q9H0U3,P04843 11 +esterase 0.6752161170357188 1.728283137498732 0.083937474731057 0.9999993779946796 0.1606386557307368 8 Q9NUJ1,O14734,Q969T7,Q9H0P0 4 +ion channel 0.6553984947629428 1.5346315331636404 0.1248743624163948 0.9999999996390256 0.2143652633437989 7 Q9C0H2,Q96S66,P51790 3 +glycosidase 0.651037676250988 1.4294499444339666 0.152874952124371 0.9999999999981992 0.2513780690212431 6 Q9BTY2,P06865,P07686,P04066 4 +cadherin 0.5958205583373564 1.3493507345968594 0.1772243368501906 0.9999999999999843 0.2804618146270007 5 Q14574 1 +membrane traffic protein 0.3305332557656211 1.175849984280724 0.2396548283393849 1.0 0.3551248819938158 68 O60313,Q9H6H4,Q9BRG1,Q96PC5,Q00765,O43633,Q9BQT9,Q9H223,Q96D71,P40855,A6NIH7,P51572,Q6NUK4,Q9NX40,P43307 15 +vesicle coat protein 0.3879483992797597 0.979366065509086 0.327399137954393 1.0 0.4522547414115768 27 Q9Y3A6,P49755,Q9BVK6,Q15363,P09496,Q13445 6 +chaperone 0.3055215142683792 0.9405102049396832 0.3469559175920604 1.0 0.4726323954600604 73 O95456,Q16543,Q9Y2R0,P30533,Q9NWM8,Q96KC8,P78318,Q96JJ7,Q8N183,O75937,O15260,Q9Y680,Q9UHV9,O95433,P07237,O00170,Q8N5M1,Q99426,Q9BRT2,P46379,P27824,O60884,Q9NVH1 23 +metalloprotease 0.3786935534198362 0.921490908857432 0.3567941854775791 1.0 0.4767203605605407 28 P22695,P42892,Q10713,O75844,Q9UIQ6,P55786 6 +acyltransferase 0.4385378540827044 0.904412778316197 0.3657765649204587 1.0 0.4781708379804167 15 P50416,Q9BWD1,P35610,Q86UL3,Q9HCL2,P23786,Q92604 7 +translation release factor 0.4058614564831398 0.7349715708556339 0.4623568082252349 1.0 0.5787560960274994 3 Q14197,Q96E11 2 +calcium-binding protein 0.4697631358326972 0.7161584847481479 0.4738934943566915 1.0 0.5851866634859145 5 P20073 1 +Hsp90 family chaperone 0.4216760438258672 0.628744940200858 0.5295160516318691 1.0 0.6300081490218589 4 P07900,Q12931,P14625 3 +lyase 0.3968686163736051 0.5938315877786152 0.5526247595573932 1.0 0.6521717802156172 14 Q9BU89,P22830,Q9UHG3 3 +transferase 0.3228306326120095 0.5442127156939506 0.5862951026101428 1.0 0.6777737711025056 32 Q9BVG9,Q99735,Q8NCH0,O43505,Q7LGA3,O95674,P43490 7 +cytoskeletal protein 0.425842969365955 0.4215972293715678 0.6733190289382343 1.0 0.7569034601167737 7 Q14141,P27105,Q15019 3 +hydrolase 0.3180973134155678 0.3628949924109302 0.7166833276096147 1.0 0.7893201513538325 22 P15586,Q9BQG2,P07099 3 +heterotrimeric G-protein 0.4166319290596557 0.3470348026041513 0.7285651729253559 1.0 0.7899550855304102 6 P63218,Q8NHH9 2 +kinase 0.286014773407453 0.1452490245433713 0.8845142603212666 1.0 0.91250521792637 22 P35790,Q9BRR6,Q13232,Q8TBX8,Q9NVE7,Q9HBU6,P52789,Q9BTU6,Q8WVC6 9 +cysteine protease 0.2677283290195564 0.0296731039838814 0.976327762384777 1.0 1.0 26 P07858,Q13510 2 +nucleotide phosphatase 0.3039078601727597 0.005892360395585 0.995298603819035 1.0 1.0 6 Q8WVQ1 1 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..275e3260b25526d3015cfbbf78ee1e449d86f82f --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "C4 zinc finger nuclear receptor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "Lambda repressor-like transcription factor", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic helix-loop-helix transcription factor", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "cell junction protein", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "hydroxylase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "zinc finger transcription factor"], "available_proteins": ["AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC7", "ANKFY1", "ANKHD1", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOBEC3C", "APOL2", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARHGEF1", "ARIH1", "ARL1", "ARL6IP5", "ARPC1A", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD5", "ATG4B", "ATL2", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BAG6", "BAIAP2", "BAP18", "BAZ2A", "BCAP31", "BCAS2", "BCAT2", "BCLAF1", "BDH2", "BLM", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD7", "BRIX1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "C1D", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX8", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC6", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CENPB", "CEP135", "CEP170", "CEP250", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNP", "COA3", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAKD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DECR1", "DEK", "DENR", "DERL1", "DERL2", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZH2", "EZR", "FAHD1", "FAHD2A", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GLA", "GLB1", "GLB1L2", "GLDC", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLT1B", "GOPC", "GOSR1", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGN1", "HMGN3", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HP1BP3", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INTS11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR3", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRP1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRRFIP2", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTN1", "LYAR", "LYPLA1", "LZTFL1", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "METAP1", "METTL13", "METTL15", "MFAP1", "MFSD3", "MFSD5", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINPP1", "MIPEP", "MKRN2", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCDN", "NCK1", "NCK2", "NCKIPSD", "NCOA5", "ND1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NENF", "NEU1", "NF2", "NFRKB", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NKTR", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NOVA2", "NPEPPS", "NPM1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PARG", "PARN", "PARP1", "PARP2", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDZD11", "PEBP1", "PECR", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBFOX2", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REL", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RNASEH2A", "RNF14", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTN4IP1", "RXRB", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHC1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIN3B", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC38A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNAP29", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STK4", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TALDO1", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TERF2IP", "TES", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM9", "TJP1", "TJP2", "TK1", "TKT", "TM9SF2", "TM9SF3", "TM9SF4", "TMED1", 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0.0113288364707524 4.995145631067961 15.616504854368932 0.6819760311565471 0.3553057475304781 2.5561606009064737 1.187932616128487 1.149561543758102 0.2999604229905949 0.0049168061240519 0.1049896535105009 0.0013656945298514 0.0020400745925255 0.0043329575683166 +Signaling 7 20 2.439222370169196 0.0147189077923945 5.66747572815534 18.009708737864077 1.330299096012152 0.2668377480945127 2.507969905227609 1.6994867622232877 1.0107551340834326 0.2926688105318188 0.5122878947297459 0.0667099047189351 0.2103897150851625 0.3571368988977866 0.2565571949899699 +Oxidase 12 22 2.425427416419342 0.0152903729809135 6.703883495145631 19.237864077669904 1.0247065178117305 0.263154064152295 3.1321515397534676 1.9967748999180144 1.3264616190823058 0.2799417791483025 5.265875387189801e-05 0.1471951297158956 0.0405463165390607 0.0001189444497952 2.279269041182348e-06 +Membrane trafficking regulatory protein 3 21 2.321957234519702 0.0202352384798443 4.560679611650485 20.218446601941743 0.5159227056829229 0.4386866271320015 2.6094874555832708 2.7661001804550924 1.1256129588723178 0.3307884378613797 0.0523560596797809 0.0204708743585679 0.0733374275738533 0.0244406528674846 0.1838658218206393 +Calcium-binding protein 9 22 2.2726737203952885 0.0230458494485461 6.135922330097087 18.021844660194176 1.3650952896045327 0.2072953623045914 2.3371152398743247 2.2037057261181348 1.237653756718734 0.2545563939054063 0.0026973635349428 0.0204708743585679 0.0733374275738533 0.0244406528674846 0.0003118568141161 +Receptor 9 26 2.2051372067071773 0.0274444679001744 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 0.0450151111812413 0.0919108957066336 0.0838856775027136 0.042986650845386 0.0332373480297549 +Mitochondrial nucleotide transporter subfamily 6 8 2.140727928334107 0.0322959849387551 4.216019417475728 9.065533980582524 1.5870110662923598 0.1668197633609344 2.720728714423222 1.1029864386277723 1.1616247375257451 0.2431804664231326 0.009996551282915 0.0022827689145391 0.0090253131212995 0.0050923434600555 0.0049176108076387 +F-type ATPase 5 8 2.139449227696364 0.0323993037068481 3.174757281553398 7.754854368932039 0.3978961134348252 0.300656405601223 2.006916121747128 0.8649601417133376 1.341428125637103 0.2766885427231999 0.0432787476847939 0.0516364610584135 0.1018169846714528 0.0276231155809849 0.0140894483762481 +Extracellular structure 2 10 2.0951716741760573 0.0361557343167919 2.842233009708738 8.092233009708737 0.8560017356043709 0.3472532488838395 1.4285109580808126 1.0866524100509705 0.962827743376652 0.290186194394739 0.1901881882333377 1.0 1.0 0.4704807306772423 0.1303826157459173 +Deaminase 0 5 1.998095063469309 0.0457063548415943 1.2548543689320388 3.6941747572815538 0.1415500912691308 0.5031165428656567 1.2090278242300572 1.13576673069221 1.067894225549992 0.3178586169935747 0.3747076822525905 0.0697581245313758 0.1362380906066266 0.3069124011154697 0.5269580067311792 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f6814967206c06da7d92c16c4162422791a4d7ad --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 2124, + "title": "Average number of proteins per term", + "value": 3.134651600753296 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..01c045521a8512e2e6c16a72b4a48344a64f2057 --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8e1e7a0753f57af4c91e481d76040517684c7575 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,64 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter 0.5487367016368219 5.245286079108937 1.560400155114119e-07 0.0003313741022763 0.0001367411693056 196 Q13277,Q00765,P05023,P24390,O43731,P00846,P06576,Q13445,Q6NUK4,P16615,Q70HW3,Q9H2D1,Q9UBX3,P11279,Q9BQE5,P49257,P51809,O43752,Q9Y487,Q93050,Q15363,Q9H0U3,P28288,P13473,P61421,Q9P2W9,Q99808,Q9Y619,P54105,O95202,Q9C0E2,Q9HC07,O95249,P56385,Q8TB61,P05026,O96008,Q9BSK2,O43772,P17900,Q9HD45,P12236,Q9H2V7,Q6NUK1,Q9Y289,O60749,Q02978,O43760,Q96NB2,P24539,Q9H9B4,Q96QD8,Q15758,P12235,Q9Y6M7,P30825,O60499,Q15388,Q8NEW0,Q9Y6C9,Q9BQT8,P09496,P53985,Q92973,Q9BVK6,Q7L0J3,Q8NFH4,P36542,P49755,Q9NZJ7,Q99805,O43808,Q8N1F7,P08183,Q92544,Q9H6H4,Q9Y3A6,Q13190,P51572,O95721,Q8IXU6,P98194,O15400,Q9H936,P56134 85 +SLC superfamily of solute carriers 0.6645265376999426 3.862735573106411 0.0001121243549362 0.2119277316375712 0.0004141776171905 46 Q8TB61,Q9BSK2,O43772,Q70HW3,Q9H2D1,P12236,Q9H2V7,Q9Y6C9,Q9BQT8,Q6NUK1,Q9UBX3,Q9Y289,P53985,Q02978,Q96NB2,Q8IXU6,Q7L0J3,Q9H0U3,Q9H9B4,Q96QD8,Q15758,Q99808,Q9Y619,Q9NZJ7,O95202,Q9Y6M7,P30825,Q9H936,O43808,Q9HC07,Q8NEW0 31 +Miscellaneous SLC25 mitochondrial transporters 0.8940514945250079 3.6924534863266247 0.0002221009713474 0.3761185159943732 0.0006625596392443 2 Q9Y6C9 1 +Galactosidase 0.878958271678012 3.6195142888690848 0.000295156513306 0.4658106800517349 0.0008151918616644 2 Q8IW92 1 +AKT family 0.8768866528558753 3.609451137931989 0.00030684556345 0.4789138985524534 0.0008372710154644 2 P31751 1 +SLC35 family of nucleotide sugar transporters 0.8659366676531534 3.5560494468448556 0.0003764732513129 0.550572057167671 0.000971615442927 2 Q8TB61 1 +Chloride channel family 0.8342704942290634 3.3995819313572606 0.0006748895683159 0.7616343348742618 0.0015347595750568 2 P51790 1 +SLC25 family of mitochondrial transporters 0.7184800626575154 3.2536089466079976 0.001139490218085 0.911225622540734 0.002342959557805 21 Q70HW3,Q9H2D1,P12236,Q02978,Q9Y6C9,Q9Y619,Q9BQT8,Q9NZJ7,Q6NUK1,Q9BSK2,Q9UBX3,Q9H936,O43808,O43772 14 +CDK1 subfamily 0.8043799940810913 3.2490209548598927 0.001158029471066 0.9146572581546152 0.0023741839734982 2 P24941 1 +SLC56 Sideroflexins 0.7848475880438024 3.1490757232521407 0.0016378774877487 0.9692450359474032 0.0031454356093837 2 Q96NB2 1 +Aspartic protease 0.9091889411742952 3.0766898798873283 0.0020931294281358 0.9883268766920108 0.0038358989692498 4 Q5BJF2,Q8TCT9 2 +ERK subfamily 0.6978395975140615 2.6880318793358637 0.0071874534396048 0.9999997781529788 0.0106980736550249 2 P27361 1 +Na+/K+-ATPases 0.7572528123149757 2.6721219659932376 0.0075373247400838 0.9999998950641056 0.0111154606018345 3 P05026,P05023 2 +SNARE protein 0.756083366077149 2.5932894325562548 0.0095062731404742 0.9999999984544852 0.0135149425370597 12 Q9P2W9,Q13277,O95721,O15400,Q13190,O60499,O95249,O43752 8 +F-type and V-type ATPases 0.6824019682960792 2.532388589598685 0.0113288364707524 0.9999999999690852 0.0156860812671956 16 P36542,P24539,Q93050,P00846,P56134,P06576,Q9Y487,P61421 8 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.787903664237994 2.516693124661478 0.0118461957803528 0.9999999999898296 0.0162961916045786 4 Q9UBX3 1 +Signaling 0.5996293747546061 2.4392223701691957 0.0147189077923945 0.999999999999979 0.0195393500944038 20 O00264,Q99627,Q8WUJ1,Q07820,O15173,Q96PC5,P43490 7 +Oxidase 0.5896346733369555 2.425427416419342 0.0152903729809135 0.999999999999994 0.0201772019897208 22 O75880,Q15067,P36551,O43169,O15260,P14406,P20674,P15954,O75845,O15254,Q15800,Q6ZRP7 12 +Ca2+-ATPases 0.7048549437536874 2.403254483398002 0.0162498746403725 0.9999999999999992 0.0212137269429325 3 P16615,P98194 2 +Membrane trafficking regulatory protein 0.5789551083951556 2.321957234519702 0.0202352384798443 1.0 0.0255527030506476 21 O60749,O43731,P24390 3 +Calcium-binding protein 0.5681735159541602 2.2726737203952885 0.0230458494485461 1.0 0.0285419150021644 22 Q14257,Q9BQT9,O43852,Q8IYU8,Q9BPX6,P80303,P41208,P43307,P0DP25 9 +Receptor 0.5422953557506234 2.2051372067071773 0.0274444679001744 1.0 0.0331959281434911 26 Q9GZP9,Q9NR77,Q14108,P57105,Q9BUN8,A6NIH7,Q567V2,Q8WTV0,O75381 9 +Mitochondrial nucleotide transporter subfamily 0.7591237929390489 2.140727928334107 0.0322959849387551 1.0 0.0380881021709694 8 Q70HW3,Q9H2D1,P12236,Q6NUK1,Q9BSK2,O43808 6 +F-type ATPase 0.7588580874974394 2.139449227696364 0.0323993037068481 1.0 0.0381675657644733 8 P36542,P24539,P00846,P56134,P06576 5 +Extracellular structure 0.702041632851047 2.0951716741760573 0.0361557343167919 1.0 0.0418044527429864 10 O75718,Q92791 2 +Glycosyltransferase 0.5415674554162077 1.8246775863452884 0.0680496975333462 1.0 0.0726684552844783 18 P46977,O60762,Q8TCJ2,Q10472,Q9Y2G5,P04843,Q16739,Q9BT22,Q8N128 9 +Intracellular calcium-sensing protein 0.5530969028374256 1.810823597801335 0.0701681622574132 1.0 0.0748554377874163 17 Q14257,Q99584,O43852,Q8IYU8,Q9BPX6,Q15293,P80303,P60660,P41208,P0DP25 10 +Calmodulin 0.5530969028374256 1.810823597801335 0.0701681622574132 1.0 0.0748554377874163 17 Q14257,Q99584,O43852,Q8IYU8,Q9BPX6,Q15293,P80303,P60660,P41208,P0DP25 10 +Mitochondrial amino acid transporter subfamily 0.720592592592578 1.7572279864063065 0.0788789568003682 1.0 0.0839794006235499 6 Q9Y619,Q9H936,O75746,Q8TBP6,O43772 5 +P-type ATPases 0.6925500724251458 1.7156375005453377 0.0862284103964945 1.0 0.0916203820320932 7 P16615,P05023,P05026,P98194,P54709 5 +V-type ATPase 0.6563121114074149 1.6331106969358673 0.1024457172436454 1.0 0.1086344001125826 8 Q9Y487 1 +mRNA splicing factor 0.379410194143138 1.6328658707204011 0.1024972095249154 1.0 0.1086347669814972 62 P09012,Q9BWF3,Q15287,P98179,Q07955,Q16629,P35637,Q07666,P84103,Q9UK45,P62995,Q15233,P38159,Q92804,P62310,Q13595,Q14011,Q96E39,Q01844,P23246,Q96PK6,O75525 22 +Ion channel 0.6069240137487978 1.584196535305338 0.1131490015012957 1.0 0.1197451316336582 10 Q8NE86,Q9C0H2,P51798,Q96S66,P0CG08,P51790 6 +Protease 0.3272928429236076 1.5049926943421432 0.1323259550068853 1.0 0.1396226172054766 116 P10619,P07858,P42892,Q92905,P55786,Q9HB40,Q13510,Q96K76,Q5BJF2,Q8NHP8,P67812,Q8TCT9,O75844,Q9UIQ6,O14773,Q8N2K0,Q8TCT8,P22695,Q10713,Q9H3G5,P42785 21 +Esterase 0.5572031947060696 1.4734893633275177 0.1406191298606824 1.0 0.1481522975317904 12 P50897,Q969T7,O14734,Q9H0P0,Q9UMR5 5 +Oxidoreductase 0.3174687592544783 1.3534391312163565 0.1759153833553006 1.0 0.1848808878014144 120 Q8N0U8,P14406,Q9UDW1,Q96CU9,Q16850,Q9H9P8,O75438,O75306,Q6ZRP7,P00403,O75880,O15260,O43169,P36551,O15254,Q15800,Q14534,Q15067,O95831,Q15392,P03886,P00374,O75845,Q13423 24 +Oxygenase 0.5933437553037331 1.3368540345201576 0.1812702872770564 1.0 0.1903203609374532 5 Q16850 1 +Serine protease 0.4205883984153726 1.2815215237701745 0.2000105447655844 1.0 0.2094784995473872 28 P10619,Q96AE4,P61978,P67812,Q96I24,Q9H3G5,O14773,Q9HB40,Q9UNW9,Q92945,P42785,Q8N2K0 12 +Glycosidase 0.5421883690215432 1.2639602291889822 0.2062443020840141 1.0 0.215688280466 4 P06865,P07686 2 +Extracellular matrix glycoprotein 0.5692862529953959 1.2152125245434435 0.2242850447643372 1.0 0.2344396826178406 5 Q32P28 1 +Adenylate kinase family 0.4757252812315136 1.132511480897366 0.2574194603581956 1.0 0.2682821068698761 3 P54819,P00568 2 +Chromodomain 0.5405805687203705 1.0698465835835866 0.2846883701573621 1.0 0.296120518224406 5 P45973,Q14781,Q13185,P83916 4 +Vesicle coat protein 0.4063382497174413 1.057565599259732 0.290253532883145 1.0 0.3017613822045032 23 Q9Y3A6,P49755,Q9BVK6,Q15363,P09496 5 +SLC27 family of fatty acid transporters 0.3959751405741439 0.891585714165517 0.3726150301343414 1.0 0.385126191730093 2 O14975 1 +Nucleotide phosphatase 0.5039210003196062 0.850262165639628 0.3951793463150994 1.0 0.4078527364301609 8 O43681,P22413,Q8IWA4 3 +mRNA processing factor 0.2977742471688829 0.7869846037320479 0.4312908790458691 1.0 0.4438284045995281 77 P09012,Q9BWF3,P98179,Q15287,Q07955,Q16629,P35637,Q07666,Q9UK45,P84103,P62995,Q15233,P38159,Q92804,P62310,Q13595,Q14011,Q96E39,Q01844,P23246,Q96PK6,O75525 22 +TK group 0.5039046824819963 0.7275656328464342 0.4668795247401656 1.0 0.479754286670591 6 P00533,Q15375 2 +Hsp90 family chaperone 0.4216760438258672 0.628744940200858 0.5295160516318691 1.0 0.5420202861041398 4 P07900,Q12931,P14625 3 +Phosphatase inhibitor 0.4774715414012936 0.6064235879006624 0.5442335090170101 1.0 0.5568169427515074 6 Q99733,Q01105 2 +Metalloprotease 0.3214835754421825 0.5561249042026023 0.5781254712628436 1.0 0.5900713603855262 39 P22695,P42892,Q92905,Q10713,O75844,Q9UIQ6,P55786 7 +Unclassified protein 0.3499315483321791 0.5268665090957925 0.5982862925722507 1.0 0.6100624509954203 19 Q9HBU6 1 +Lyase 0.3405533876739443 0.5231632894512361 0.6008606257144995 1.0 0.6123934592214957 21 A1L0T0,Q96KA5,P22830,P61457,O96005 5 +MAPK family 0.3594334313163412 0.486582801285782 0.6265540140699368 1.0 0.6373566694849357 3 P27361 1 +Growth factor 0.4150528127769546 0.4593223462087568 0.6460027030155899 1.0 0.6568261087626199 5 Q96PC5 1 +Hydrolase 0.2622109121310048 0.4360695715859055 0.6627862533818925 1.0 0.6735684220971959 107 P00813,P50897,Q9NX62,Q9H857,Q9P0J1,P15586,Q8IY17,Q8N2A8,P16278,Q969T7,P11117,P07686,Q9NPH0,Q9UMR5,O43924,O14734,Q8IWA4,P10586,Q86YN1,P10253,O43681,P22413,P06865,Q9H0P0,Q9NVI7,Q05639,Q5T9A4,Q8IW92 28 +Reductase 0.3569621256390241 0.4296360134732144 0.6674604356068614 1.0 0.6776701554631805 16 Q14739,Q9UDW1,P00374,O95168,O95881,Q15392 6 +Heterotrimeric G-protein 0.4166319290596557 0.3470348026041513 0.7285651729253559 1.0 0.7382979137850458 6 P63218,Q8NHH9 2 +Phosphatase 0.2972262516628071 0.3191753704807182 0.7495935324896235 1.0 0.7581603157180763 32 Q86YN1,Q9NX62,P11117,O43681,P22413,Q9NPH0,P10586,Q8IWA4 8 +Immune response 0.3559395150658161 0.1342523902430721 0.8932029994162494 1.0 0.8999825288235833 6 Q9NX40 1 +ATP-binding cassette transporter family 0.3266531819728298 0.0786777797186047 0.9372889198968428 1.0 0.9426144251235292 8 P28288,P08183 2 +Exoribonuclease 0.320039887549594 0.0478008472021601 0.9618749613601992 1.0 0.966882355858525 7 Q13868,Q15024 2 +Phosphatase modulator 0.3124841791584967 0.0390525016267869 0.9688485302658696 1.0 0.973431541288887 8 Q9H0U9,P55209,Q99733,Q01105 4 +Protease inhibitor 0.2915715424355174 0.0366661053850054 0.9707512344447398 1.0 0.974882090761526 13 P05067 1 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5aadc5e638ac40dbb8014143079198bdb4b448f5 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2,4-dienoyl-CoA reductase, mitochondrial", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L23, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-aminobutyrate aminotransferase, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-1", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-formyltetrahydrofolate cyclo-ligase", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMP deaminase 2", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family B member 8, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family D member 4", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent DNA helicase Q4", "ATP-dependent DNA helicase Q5", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Acetoacetyl-CoA synthetase", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Actin-related protein 6", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amyloid-beta A4 protein", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Apoptosis-stimulating of p53 protein 2", "Arfaptin-1", "Arfaptin-2", "Arginase-2, mitochondrial", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical SLC22B subfamily", "Atypical group", "Aurora kinase b", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "BUB3-interacting and GLEBS motif-containing protein ZNF207", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-adducin", "Beta-galactosidase", "Beta-galactosidase-1-like protein 2", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 3", "Bromodomain-containing protein 4", "Bromodomain-containing protein 7", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 2", "CCR4-NOT transcription complex subunit 7", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-regulated heat-stable protein 1", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calsyntenin-3", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Catechol O-methyltransferase", "Catechol O-methyltransferase domain-containing protein 1", "Catenin alpha-1", "Catenin delta-1", "Cathepsin B", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell division cycle protein 20 homolog", "Cell surface glycoprotein MUC18", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 135 kDa", "Centrosomal protein of 170 kDa", "Centrosome-associated protein CEP250", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 6", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 2", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Clathrin heavy chain 1", "Clathrin light chain A", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Coronin-7", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-A2", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystathionine gamma-lyase", "Cystatin-B", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DDB1- and CUL4-associated factor 13", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA dC->dU-editing enzyme APOBEC-3C", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA topoisomerase 3-alpha", "DNA-3-methyladenine glycosylase", "DNA-binding protein SATB2", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase III subunit RPC6", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmocollin-2", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Diphthine methyl ester synthase", "Disintegrin and metalloproteinase domain-containing protein 9", "Disks large homolog 1", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 4", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase NEDD4", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D1", "EGFR family", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Early endosome antigen 1", "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Epidermal growth factor receptor", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethanolamine kinase 1", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP41", "Exosome complex component RRP42", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Folate transporter 1", "Follistatin-related protein 1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GDP-fucose protein O-fucosyltransferase 2", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Heparanase", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group nucleosome-binding domain-containing protein 3", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histidine triad nucleotide-binding protein 3", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase EZH2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SETD7", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-3", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF14", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIF7", "Kinesin-like protein KIFC1", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lambda repressor-like transcription factor", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Legumain", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat flightless-interacting protein 2", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "M-phase phosphoprotein 8", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 5", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 1", "MAPK family", "MARK subfamily", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MST subfamily", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Map/microtubule affinity-regulating kinase 3", "Mediator of RNA polymerase II transcription subunit 12", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 21", "Mediator of RNA polymerase II transcription subunit 25", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D1", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine aminopeptidase 1", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial cardiolipin hydrolase", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin", "Myotubularin-related protein 2", "Myotubularin-related protein 6", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] 1 subunit C2", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NLR family member X1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral amino acid transporter subfamily", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear factor related to kappa-B-binding protein", "Nuclear migration protein nudC", "Nuclear nucleic acid-binding protein C1D", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 3", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "OCIA domain-containing protein 1", "OTU domain-containing protein 7B", "Obg-like ATPase 1", "Occludin", "Origin recognition complex subunit 2", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PAX3- and PAX7-binding protein 1", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ domain-containing protein 11", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 14", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PITSLRE subfamily", "PKA family", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Paired amphipathic helix protein Sin3b", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal bifunctional enzyme", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phospholipid-transporting ATPase IG", "Phospholipid-transporting ATPases", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Pirin", "Plakophilin-2", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyhomeotic-like protein 2", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable helicase with zinc finger domain", "Probable leucine--tRNA ligase, mitochondrial", "Probable methyltransferase-like protein 15", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl 3-hydroxylase 3", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein HIRA", "Protein Hook homolog 2", "Protein LSM14 homolog B", "Protein NDRG3", "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein S100-A13", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein Wiz", "Protein XRP2", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase c delta type", "Protein methyltransferase", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein strawberry notch homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Proto-oncogene c-Rel", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyridoxine-5'-phosphate oxidase", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RILP-like protein 1", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA binding protein fox-1 homolog 2", "RNA helicase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-1", "RNA-binding protein Nova-2", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-alpha serine/threonine-protein kinase", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-type tyrosine-protein phosphatase F", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoic acid receptor rxr-beta", "Retinoid X receptors", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "S1 RNA-binding domain-containing protein 1", "SAP30-binding protein", "SEC23-interacting protein", "SET domain", "SHC-transforming protein 1", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC4 family of bicarbonate transporters", "SLC5 family of sodium-dependent glucose transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC6 neurotransmitter transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "Sarcolemmal membrane-associated protein", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Segment polarity protein dishevelled homolog DVL-2", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Separin", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-8", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase tao3", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein kinase wnk3", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sialidase-1", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters", "Sodium-coupled neutral amino acid transporter 2", "Sodium-dependent HCO3- transporters", "Sodium-dependent multivitamin transporter", "Sodium-dependent neutral amino acid transporter B(0)AT2", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 25 member 33", "Solute carrier family 25 member 40", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptic vesicle glycoprotein 2A", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Syntaxin-10", "Syntaxin-12", "Syntaxin-18", "Syntaxin-3", "Syntaxin-5", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAO subfamily", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 10A", "TBC1 domain family member 10B", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid adenoma-associated protein", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Tmem38 family", "Torsin-1A", "Torsin-1B", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 7", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor CTCF", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 1", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Trimeric intracellular cation channel type B", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tuberin", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-3 chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase lyn", "Tyrosine-protein kinase yes", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm7", "U6 snRNA-associated Sm-like protein LSm8", "UDP-glucose:glycoprotein glucosyltransferase 1", "UDP-glucuronic acid decarboxylase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 1", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-Ie", "Unconventional myosin-VI", "Upstream-binding protein 1", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 52 homolog", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "WNK family", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7B", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 3", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger ZZ-type and EF-hand domain-containing protein 1", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 7", "Zyxin", "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-decapping enzyme 1A", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA dimethylallyltransferase", "tRNA pseudouridine synthase A"], "available_proteins": ["AACS", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALYREF", "AMPD2", "ANAPC1", "ANO6", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOBEC3C", "APOL2", "APP", "ARCN1", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARIH1", "ARPC1A", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASNA1", "ASNS", "ATAD2", "ATAD3A", "ATAD3B", "ATG4B", "ATIC", "ATL2", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKB", "BAG6", "BAIAP2", "BAX", "BCAP31", "BCAS2", "BCAT2", "BCLAF1", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRIX1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "C1D", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC20", "CDC37", "CDC40", "CDC42", "CDC45", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CEBPZ", "CEP135", "CEP170", "CEP250", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNP", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DECR1", "DENR", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLG1", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENO2", "ENPP1", "EPHA7", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZH2", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FOXRED1", "FSCN1", "FSTL1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GLB1", "GLB1L2", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPR89B", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN3", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HPRT1", "HPSE", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INTS11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRRFIP2", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LTN1", "LYN", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARK3", "MAT2A", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED12", "MED14", "MED21", "MED25", "METAP1", "METTL15", "MFAP1", "MFN1", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MMS19", "MOB4", "MORF4L1", "MORF4L2", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA50", "NADK2", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCL", "NCOA5", "ND1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NEDD4", "NEDD4L", "NEK9", "NEU1", "NFRKB", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NOVA2", "NPEPPS", "NPM1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "PACSIN2", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDZD11", "PEBP1", "PECR", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PINX1", "PIP4K2C", "PIR", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT2", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PPA1", "PPA2", "PPAT", "PPIL1", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA1", "PRKACA", "PRKAG1", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPRF", "PUDP", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RBBP6", "RBFOX2", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REL", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RILPL1", "RNASEH2A", "RNF14", "RNH1", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RTCA", "RXRB", "S100A10", "S100A11", "S100A13", "SAE1", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHC1", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLK", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMN1*", "SNAP23", "SNAP29", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF7", "TAGLN2", "TAOK3", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TJP1", "TJP2", "TK1", "TKT", "TM9SF2", "TM9SF3", "TM9SF4", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM165", "TMEM38B", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOP3A", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRIT1", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UBP1", "UCHL5", "UCK2", "UGCG", "UGGT1", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP5", "USP7", "UTP11", "UTP14A", "UTP3", "UTP6", "UXS1", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS52", "VRK1", "VRK2", "WARS", "WASF2", "WDHD1", "WDR1", "WDR33", "WDR74", "WDR82", "WIZ", "WNK1", "WNK3", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YEATS4", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7B", "ZCCHC11", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF598", "ZNF622", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["ABCB1", "ABCD3", "ABHD12", "ACOT8", "ACOX1", "ACOX3", "ACP2", "ACP6", "ADA", "AIFM1", "AK1", "AK2", "AKT2", "ALG1", "APOL2", "APP", "ASAH1", "ASNA1", "ATAD3A", "ATAD3B", "ATL2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2C1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "BCAP31", "CALM3", "CALU", "CBX1", "CBX2", "CBX3", "CBX5", "CDK2", "CETN2", "CIRBP", "CLCC1", "CLCN3", "CLCN7", "CLNS1A", "CLPTM1", "CLPTM1L", "CLSTN3", "CLTA", "COPS5", "COPS8", "COX2", "COX5A", "COX7A2", "COX7C", "CPOX", "CPVL", "CRTAP", "CTSA", "CTSB", "CYB5B", "CYB5D2", "CYP51A1", "DERL1", "DERL2", "DHCR24", "DHFR", "DOLPP1", "DPM1", "ECE1", "EEF1A2", "EGFR", "ENPP1", "EPHA7", "ETNK1", "EWSR1", "EXOSC2", "EXOSC7", "FAM177A1", "FECH", "FOXRED1", "FUBP1", "FUBP3", "FUS", "GAA", "GALNT1", "GLB1", "GLB1L2", "GM2A", "GNG5", "GNS", "GOSR1", "GPR89B", "HEXA", "HEXB", "HM13", "HNRNPK", "HSP90AA1", "HSP90B1", "ILVBL", "IMPAD1", "KDELR1", "KDELR3", "KHDRBS1", "KHDRBS3", "KHSRP", "L2HGDH", "LAMP1", "LAMP2", "LBR", "LETM1", "LMAN1", "LNPEP", "LSM3", "LSM7", "MAGT1", "MAPK3", "MCL1", "MCU", "MFN1", "MIA2", "MICU1", "MICU2", "MPV17L2", "MSMO1", "MTCH1", "MTCH2", "MYL6", "NAMPT", "NAP1L1", "NAP1L4", "ND1", "NDUFB1", "NDUFB4", "NDUFS2", "NNT", "NONO", "NOVA2", "NPEPPS", "NT5C3A", "NT5C3B", "NT5DC2", "NUCB2", "NUP37", "NUP93", "OCIAD1", "P3H1", "P3H4", "PCBD1", "PDE6D", "PDP1", "PEX14", "PGRMC1", "PGRMC2", "PLBD2", "PLD6", "PMPCA", "PNPLA6", "POFUT2", "PPT1", "PPT2", "PRCP", "PTPRF", "PXMP2", "QSOX2", "RBM14", "RBM3", "RBM4", "RBMX", "RBMXL1", "RCN1", "RCN2", "REEP3", "REEP4", "REEP5", "RNPS1", "RPN1", "S100A13", "SC5D", "SCARB1", "SCARB2", "SCO1", "SCPEP1", "SEC11A", "SET", "SFPQ", "SFXN1", "SFXN2", "SLC16A1", "SLC1A5", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A6", "SLC27A2", "SLC29A1", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC4A7", "SLC5A6", "SLC7A1", "SNAP29", "SNRPA", "SNX2", "SPNS1", "SPPL2A", "SQLE", "SRSF1", "SRSF3", "SRSF7", "SSR1", "STT3A", "STT3B", "STX10", "STX18", "STX3", "STX5", "STX6", "STX7", "SURF4", "SV2A", "SYNGR2", "SYNJ2BP", "TAF15", "TM9SF2", "TM9SF3", "TM9SF4", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM165", "TMEM97", "TNPO1", "TOMM20", "TOMM40", "TPP1", "TRA2A", "TRA2B", "TRAP1", "TSPYL1", "TTYH3", "TXNDC12", "UGCG", "UNC119B", "UQCR10", "UQCRC2", "USP47", "VAMP7", "VKORC1L1", "XPO4", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6e0847ffc649d08286e63465c7dfff7898d31ecd --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..3f78b4b3aded5ac930cb52af8b9f8e9783700025 --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a9c87d75919f9cad5dba305453228dfefe5af950c2d8c4195b4c447878a7f0f2 +size 215592 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..272c50b246caab30b57be31f12c43fc82de33f93 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio", "1": "Tclin", "2": "Tdark"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..dd54a963bb53f587edd5ff6c31b1e8316bb52373 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:34872cf5a9aa23dfec15dbd9685802c2829e6a4e3f77d2542637c95549459420 +size 130502 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..61e1cb6c51a90c3cf10899bf859399cd7c571576 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f8b7eb64732865f325f42cc522b0225f019f50ee6ab8952926cac9bfb8e695d2 +size 132343 diff --git a/pharos_protein_category/basic/plot_2.png b/pharos_protein_category/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..7710441dbf66b392abcee27c650ce3931b9566dd --- /dev/null +++ b/pharos_protein_category/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:202e7cfb23aa89bc9d6b03282ba34b777ea4d59330a139dbfa272d2541af3340 +size 134181 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..cc8e1619c77bc1a1b092e246e4dcf64e3c5a5b77 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3b11eb16f5066ee40c5f3701dd183375ba6c8396e4e7940ac11ff881d7022997 +size 83656 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d21628eeff0b1d4d94b257805a614e46a7997fe1 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tbio 403 2595 4.557598856048548 5.174173914213043e-06 467.6796116504854 2434.25 -0.5416405556668178 0.3215141878443288 119.73666199244032 234.70955636597876 4.704421961664106 0.4116627836259234 0.0208755241759393 0.7431074539397013 0.2854144931569098 0.1356968002978773 0.0027825919166186 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3f3e7f68b03cca4ba01dda513cff3dda1fedd092 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 845.0 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7e15078ec55194d164fbbae46641ededb6a236bd --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..82491ae728cef02b54248f8503b7fe564c87ee35 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tbio 0.2066469417681102 4.557598856048548 5.174173914213043e-06 2.0696535024956094e-05 2.0696695656856172e-05 2595 Q9NS69,P50897,P24390,Q14108,P49069,Q99595,Q8N0U8,O15173,Q9UDW1,O60637,P21796,Q9Y2R0,Q9UDX5,P00846,Q9H9P8,P80303,O43657,Q9HB40,P43307,Q9H6V9,Q70HW3,Q9H2D1,O00264,O15260,P22830,Q9UBX3,Q9C0H2,Q8WY22,O75629,Q9Y282,Q8IV08,Q9HBU6,P07602,O15254,Q9NPH0,Q2M389,Q9BQE5,O95772,Q14849,Q8IZA0,Q9UMR5,O43805,O43752,P54802,Q9Y487,Q9Y5Y5,Q8N511,O95433,Q9BRR6,Q8NHP8,Q96A26,P67812,P33908,Q8TCT9,Q8NCH0,Q96JX3,Q93050,Q15363,Q9UHG3,Q6P4A7,O95831,Q96FZ2,O75844,O75503,O14773,P33991,O14949,O00461,Q8NBZ7,P98175,Q9P2W9,Q14257,Q9Y619,Q9Y3B8,O95202,P22695,P57105,Q9UHX1,Q9HC07,O95249,Q13423,Q9NZQ3,O96005,Q567V2,P52756,O15127,Q7RTS9,Q9GZS3,P51648,O75153,O14925,P98179,O14737,Q8TB61,Q9BWD1,Q9BSK2,Q92791,Q6DKK2,P56378,P15586,Q68CQ7,Q9NQX7,Q86XL3,Q96L92,P17900,P35637,P55010,Q9H061,Q9NUJ1,Q9NWM8,Q9UL15,Q5T9L3,Q9H2V7,Q96KC8,P27544,O43169,Q13505,Q15041,P35613,Q9BQG2,Q9H1D9,O95197,Q9BUN8,Q9Y277,Q9Y680,Q15800,O15212,O60749,P41208,Q9UK61,Q9UKU0,Q9Y287,Q9Y5J9,Q8NEY8,Q9BTX1,P13073,O43760,Q15067,Q92804,O75298,O95905,Q8NI60,P24539,Q9UMX5,Q8NBX0,Q9HCL2,P08670,Q9UJX3,Q7LGA3,Q96G23,Q96D71,Q9NQC3,Q9UNI6,Q96QD8,O43464,O60220,P28072,Q96A33,Q9BZG1,Q8TCT8,Q14011,Q9NR28,O00584,P61020,Q07065,Q8N8Q8,Q9H0B6,Q9Y6M7,P67809,P30825,O60499,P31942,P35269,Q10713,O43292,Q01844,Q9H3G5,Q9H6K4,O14979,Q15388,Q8NEW0,Q9UBS8,O75525,P07196,Q8NBT2,Q9UBV2,Q9GZP9,Q96KA5,O95456,O43852,P09493,Q96D09,O00231,Q96CU9,Q9BPX6,Q9BV86,Q92905,Q9H9S5,Q8N2A8,Q96HY6,Q969Q5,P40855,P27105,O15031,Q5XKP0,Q6ZRP7,Q9H3K2,Q9NX40,P48723,Q9NX63,Q9BPZ3,O15118,P16949,O75718,O43251,Q16204,Q9Y6C9,Q96JJ7,Q9BQT8,Q9P035,Q96DF8,P20339,P11117,Q6P2P2,Q9Y297,O43505,P61916,Q99729,Q9UBG0,Q8N5M9,P50402,P09496,O60506,P31943,P38159,O75208,Q14C86,Q9BU89,Q9UM22,Q9UG56,Q10472,Q32P28,Q92973,Q9BVG9,Q99735,Q9UEE9,Q8N3R9,P10909,Q08722,Q3ZCQ8,Q9Y5X3,Q71SY5,Q9NSD9,Q9NR31,Q8IWA4,Q15392,Q15165,Q14527,P52597,P46977,P36542,P48637,P49755,Q92542,Q9UGR2,Q9BZD4,Q9NZJ7,Q9NQ50,Q96N66,P07197,O43808,O75845,O14681,P20073,Q8N1F7,Q96S66,Q9H0P0,Q9NVI7,Q96BR5,Q96AE4,Q8IYU8,O95684,O75381,O15258,Q92544,Q9H6H4,Q9BRG1,Q9Y3A6,Q9UMX0,Q9BQT9,P61978,O15498,Q13190,P55795,P01889,Q01105,Q15024,Q86Y07,Q9H2J4,O94927,A6NIH7,O43768,P09669,P51572,Q86UY6,P61019,Q9H4A5,P22626,O95721,O43633,O75880,P16435,P36551,Q14739,Q92520,Q9GZY8,Q8WVQ1,Q9H4A6,Q969X5,Q99442,Q86UL3,O60888,O43390,O95674,Q14574,Q8NHH9,Q96PC5,Q9Y5J7,Q86UE4,Q9UHV9,Q6UXV4,O60313,A1L0T0,P51571,Q08J23,Q99733,Q9BXK5,Q9BV57,P55327,P10321,P98194,Q9UL46,Q86YV9,Q92896,Q8WXW3,Q9Y4P3,Q16625,P61457,Q9Y262,Q9BUB7,Q8N5M1,Q5BKZ1,Q9UQB8,Q9NQZ5,Q96EK5,Q53GQ0,Q15555,P46379,P31483,O15400,O15460,Q13501,Q6NUM9,Q96I24,Q14103,Q9H936,Q9BW92,Q9H223,P53701,O43681,O75915,O95747,P04843,P56134,Q12981,Q5M775,Q8NDZ4,Q9UNW9,Q9UHB9,Q9P2S5,Q9H6S0,P09012,Q15907,Q13277,Q05086,Q00765,Q99584,Q96PU5,Q16740,Q9H6D7,Q5T8D3,P30260,Q16543,P20674,P48651,Q9P0J1,Q9NZW5,Q9BT22,Q13011,P61289,P06576,O14828,O95881 403 +Tclin 0.3534021433032656 1.9016030906758756 0.0572230635846751 0.2099841609713166 0.0772424848631011 96 P00813,P06280,P28074,P05023,P62942,P20618,P05026,O43674,P00533,P21964,Q16739,O75438,O43676,O75306,Q99720,Q8N183,Q9NX14,P48735,P54709,O95168,Q86Y39,Q9Y2I1,P0DP25,O95298,O75116,O43924,Q9Y6M9,P38435,Q7L0J3,P56556,Q99808,O75489,P03886,P49841,P00374,P10253,P51970,P55011,P49721,Q06203 40 +Tdark 0.2826369165745726 1.109235341018778 0.2673286703666984 0.7118379470735874 0.2673286703666984 348 O60830,Q567U6,O43731,Q69YU5,O75964,Q92564,Q8N4H5,Q13445,Q8WVC6,Q9BWJ5,Q969T7,Q6PK18,Q9NR77,Q16540,Q5R3I4,O43615,Q7Z7F7,Q15629,Q8N8L6,Q9NPL8,Q6NUQ4,Q5J8M3,Q5VW38,Q9BSJ5,Q9BSH5,Q5HYI7,Q9NRY5,Q86YN1,Q9NX00,Q9Y5M8,Q9BRV8,Q96GQ5,Q9NUD5,Q9HD20,P15954,Q3SXM5,Q8N201,O94919,Q8NC54,P14406,Q96C92,Q9H910,Q9H857,Q86YQ8,Q9H1E5,Q8IYS2,Q8N128,Q9HD45,O95302,L0R6Q1,Q9H4I3,Q70UQ0,Q9NU23,Q6UW02,O95070,Q9NRG0,P82933,Q9Y2W6,Q9NPA0,Q9NPR9,Q9NUQ9,Q96DB5,Q9BVK6,P84157,Q8WUJ1,Q8NFH4,Q99805,Q8IW92,Q9NX62,Q96C01,Q9BVG4,Q9BWH2,Q86U38,O60476,Q9Y6I9,O15126,Q8IXU6,Q9NWR8,P17152,Q9BU23,P0CG08,Q96SK2,Q96IX5,Q6UW68,Q9Y3E0 85 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..698fd5d44ad6b4d98553044abd75011530ab6388 --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C16orf58", "C17orf80", "C19orf25", "C19orf47", "C19orf70", "C1D", "C1QBP", "C1orf123", "C1orf35", "C2CD2L", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC8", "CCDC86", "CCDC93", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDR2L", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP135", "CEP170", "CEP250", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX18", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM210B", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNBP4", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN3", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HPS3", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRRFIP2", "LRSAM1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METAP1", "METTL13", "METTL15", "MFAP1", "MFF", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MMS22L", "MOB4", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCK1", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PAWR", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETREG2", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RILPL1", "RINT1", "RIOX1", "RIOX2", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIKE1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM177", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC5", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBLCP1", "UBN2", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "UROD", "USE1", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS52", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WNK1", "WNK3", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["ABHD10", "ACAT2", "ACBD5", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL6", "ADA", "ADI1", "ADPGK", "AHSA1", "AIFM1", "ALDH3A2", "ALG1", "ANAPC7", "ANKLE2", "ANXA7", "APOL2", "APOOL", "ARL10", "ARL6IP1", "ARL6IP5", "ASNA1", "ATAD3A", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2C1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5J2", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATPAF2", "B4GAT1", "BAG5", "BAG6", "BAIAP2", "BCAP31", "BCL2L13", "BNIP1", "BRI3BP", "BSG", "BTRC", "C12orf73", "C14orf2", "C16orf58", "C17orf80", "C19orf70", "C3orf58", "C5orf15", "CALM3", "CALU", "CAMLG", "CANT1", "CCDC47", "CCDC6", "CCDC93", "CD47", "CDC27", "CDC37", "CDS2", "CERS1", "CERS2", "CETN2", "CFDP1", "CHCHD3", "CHMP2A", "CHRAC1", "CHST14", "CIRBP", "CKAP4", "CLCC1", "CLN5", "CLPP", "CLPTM1", "CLPTM1L", "CLSTN3", "CLTA", "CLU", "CLUH", "COA3", "COA7", "COMT", "COPS5", "COQ8A", "COQ9", "COX18", "COX4I1", "COX5A", "COX6C", "COX7A2", "COX7C", "CPNE8", "CPOX", "CPVL", "CREG1", "CRTAP", "CUTA", "CYB5B", "CYB5D2", "CYP20A1", "DCAKD", "DCUN1D4", "DDRGK1", "DERL1", "DERL2", "DHCR24", "DHFR", "DIABLO", "DNAJC1", "DOHH", "DOLPP1", "DSC3", "DUSP12", "DYM", "ECD", "ECH1", "EGFR", "EHD4", "EI24", "EIF3L", "EIF5", "EMC4", "EMC7", "EMD", "ENDOD1", "ENSA", "EPDR1", "ERGIC1", "ERGIC3", "ESS2", "ETNK1", "EWSR1", "EXOSC7", "FAM114A2", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM3C", "FAM49B", "FARSB", "FECH", "FGFR1OP", "FKBP14", "FKBP1A", "FKBP7", "FKBP9", "FKRP", "FOXRED1", "FUBP1", "FUBP3", "FUNDC2", "FUS", "GAA", "GALNT1", "GAPVD1", "GGCX", "GHITM", "GLA", "GLB1L2", "GLG1", "GLT8D1", "GM2A", "GNS", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOSR1", "GPAA1", "GPAM", "GPAT4", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GSK3B", "GSS", "GTF2F1", "HACD3", "HAUS4", "HAUS5", "HCCS", "HDHD3", "HLA-B", "HLA-C", "HLTF", "HM13", "HMCES", "HNRNPA2B1", "HNRNPAB", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPR", "HPS6", "HS2ST1", "HSD17B12", "HSDL1", "HSPA13", "HTRA2", "IDH2", "IKBIP", "ILVBL", "IMPAD1", "INTS1", "ITM2B", "ITM2C", "JAGN1", "JPT2", "KDELR1", "KDELR3", "KHDRBS3", "KIAA0319L", "KIAA2013", "KIFBP", "KLC2", "L2HGDH", "LBR", "LDAH", "LETM1", "LMF2", "LYRM2", "MAN1A1", "MAN1A2", "MAPRE2", "MBOAT7", "MCM4", "MCUB", "MED25", "MFF", "MFN1", "MGST2", "MIA2", "MICU1", "MICU2", "MPP5", "MPP6", "MPV17L2", "MRC2", "MRPL23", "MRPL40", "MRPL55", "MRPS9", "MSMO1", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTX1", "MTX3", "MXRA7", "NAA40", "NAGLU", "NAP1L4", "NCKIPSD", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFA6", "NDUFA8", "NDUFAF2", "NDUFB1", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS2", "NDUFS3", "NEDD4L", "NEFL", "NEFM", "NENF", "NISCH", "NNT", "NOP9", "NOVA2", "NPC1", "NPC2", "NSUN2", "NT5C3A", "NT5C3B", "NT5DC2", "NTMT1", "NUCB2", "NUDT12", "NUF2", "NUP37", "NUP93", "OCIAD1", "OCLN", "OGFOD3", "OPA1", "OPA3", "OXSR1", "P3H1", "P3H4", "P4HA2", "PAIP2", "PBDC1", "PCBD1", "PCYOX1", "PDCD5", "PDCL3", "PDE6D", "PDP1", "PEX14", "PEX16", "PEX19", "PFDN2", "PFDN6", "PGRMC1", "PGRMC2", "PIBF1", "PISD", "PLBD2", "PLD3", "PLD6", "PLXNB2", "PMPCA", 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a/protein_atlas_biological_process/df_merge.tsv b/protein_atlas_biological_process/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..79bbc903cbe97095ee0c9df41e2f69c8f38294a0 --- /dev/null +++ b/protein_atlas_biological_process/df_merge.tsv @@ -0,0 +1,20 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transport 192 530 5.944165537545234 2.7786869144229713e-09 127.39320388349516 491.7621359223301 1.4832290368286314 0.5289485259644714 40.31460927260851 50.077723312236 2.248556521823017 0.4543981544818752 6.959724292477555e-10 1.0490899292398224e-06 4.130377956740879e-08 8.743876147615663e-10 3.346422286651444e-15 +Ion transport 30 58 4.021384593848078 5.7857052236487405e-05 19.82766990291262 54.68446601941748 1.177785596906995 0.303722365376275 8.99659651977233 7.41832233515522 1.8666057057567336 0.3607289685223158 0.0024395624678084 0.0021892244153217 0.0026038817007042 0.0023741193871749 0.0010586375578151 +Protein transport 83 274 3.495565324329853 0.0004730586425136 60.970873786407765 250.03155339805824 0.5647835050770387 0.6753991045983436 18.49610628700502 28.95320084782557 1.0712917387948182 0.3856428267622117 0.0009074007529182 0.0482776184460361 0.0072159016791179 0.0008591310105846 1.4489080476773444e-06 +ER-Golgi transport 14 54 3.4184751241946305 0.0006297307383555 13.189320388349516 50.09466019417476 1.0113245710455496 0.4417664900586612 5.844513029144237 4.526971021787617 1.2802141654412966 0.393016134031976 0.0008259478615142 0.0005969016459399 0.0001297463919402 0.0007216204137279 6.832058638435191e-06 +Translocation 14 50 3.284097885089435 0.0010230938147317 12.434466019417476 47.86165048543689 1.1297087783550883 0.3515144245437065 6.687771513864753 3.601211391947168 1.550426642680832 0.3811939235350816 0.0004223116704045 0.0053226708337122 0.0057249284475035 6.740249353507396e-05 2.0959915925833104e-06 +Sphingolipid metabolism 6 11 3.035048018091255 0.0024049739375773 5.075242718446602 9.720873786407768 1.0723891387155546 0.1672146303539832 2.245095774833478 1.0461446620678432 1.744521381224598 0.248179764200939 9.00540026123656e-07 0.0036723611473879 8.138357715951531e-07 3.86876847347757e-06 1.8677763344678236e-05 +Hydrogen ion transport 9 20 2.795368191909656 0.0051840636465083 6.152912621359223 19.560679611650485 0.8019462838912398 0.3170771992837126 2.890966221074556 1.405159537040464 1.2709247974732976 0.29451915785821 0.0023593876836306 0.0096266028600564 0.0002151657881401 0.0007982079470274 0.0033472823991884 +Respiratory chain 15 35 2.6525380181329585 0.0079889130572723 10.895631067961164 31.91990291262136 1.1075564231308468 0.3095707256998049 4.44287149555612 3.6670789399383112 1.4970961025113558 0.3356221172021658 9.405834776595191e-05 0.003086924646434 0.0028574061260132 9.996092046331004e-05 3.0236033691112305e-05 +Electron transport 19 48 2.6172587171768096 0.0088639129682019 14.983009708737864 45.592233009708735 1.1180311721330871 0.3315827540150002 5.69510117113123 4.184313965655804 1.5984402393879058 0.3574888993156041 0.0001860865702019 0.0112094197529472 0.0145653075103282 0.0001110444187801 0.0002345207007022 +Apoptosis 41 130 2.541587250377044 0.0110350400310854 26.983009708737864 120.21844660194176 0.6636399997719048 0.5877814963058052 7.904294191754799 11.993762517847651 0.9312427807662368 0.388650277956022 0.0986243065940813 0.2557045766074424 0.1436681850711889 0.0587092576236958 0.0062782654141476 +Phospholipid metabolism 11 16 2.40608901987496 0.0161243350921209 5.706310679611651 15.194174757281552 0.9499140430417652 0.282763149469861 3.1039684871946744 2.8053632837701987 1.3505948321648105 0.2868829019946007 0.0558973394214976 0.2030241760545403 0.0105712178095962 0.0262238710799836 0.0003693854345286 +Phospholipid biosynthesis 10 15 2.1760344433811025 0.0295526851706855 5.393203883495145 14.228155339805824 0.6697741038582752 0.3412824299901092 3.008201157028892 2.7679482245749822 1.3258103202069491 0.2976917551215703 0.1384505857971164 0.1835089509173778 0.0625314301217693 0.0801176308941427 0.0008092232876479 +Sterol metabolism 8 25 2.16989906938978 0.0300144928556742 7.606796116504855 25.203883495145632 1.1785484151208083 0.2872927387372206 3.1377365577760563 3.096691699470945 1.2399567569518877 0.3064799172119154 0.0033569291430655 0.2068720246529641 0.0789500483472863 0.0280832529132891 0.0004353880265266 +Porphyrin biosynthesis 1 5 2.1640912456711434 0.0304573472521487 1.5242718446601942 4.584951456310679 0.1850658064201777 0.5142916794538557 1.219538828913083 0.6932873341844618 0.9351192019360692 0.2942652247871801 0.1967019277312726 0.0331691185540615 0.0660385900079411 0.1571881112173651 0.042147958906207 +Cholesterol metabolism 7 24 2.0100237351585943 0.04442867682626 7.111650485436893 23.79854368932039 1.169709264926864 0.2871268807807383 2.8890755390042298 2.7173834172675666 1.205315163774447 0.3061468445376054 0.0024065982626419 0.1952735388158895 0.0705821305211966 0.0227330174276438 0.0013003096338674 +Amino-acid transport 5 8 1.991772810377696 0.0463959907774111 3.063106796116505 7.016990291262136 0.9299828460487652 0.271909550896337 1.9171930478617292 1.3907470472448622 1.1684874391815692 0.271335812648974 0.0586100994566341 1.0 0.2467424796819782 0.0319451393300601 0.1652047572335966 +ATP synthesis 5 8 1.9857123392861844 0.0470652740980741 2.6092233009708736 7.560679611650485 0.4760838469956283 0.2927439020529209 1.766795238887657 0.7130595396318904 1.333549443047025 0.2645430394314645 0.050899384243609 0.0014481500629001 0.0057815105752346 0.032628233248221 0.0181181417645757 +Calcium transport 5 8 1.9814026260720463 0.0475461395071117 3.7305825242718447 8.240291262135923 0.5020754788348019 0.3462849026834517 2.2148520410126937 1.861210565609195 1.3394131933179945 0.3209721672484884 0.3162409505207246 1.0 1.0 0.5955662992954859 0.1034478004905659 +Sodium transport 6 8 1.9681520619574835 0.0490505441108428 2.6432038834951457 6.033980582524272 0.3870777500167291 0.4312394754850888 1.6104565556558244 1.45275455788244 1.082646403381691 0.3149069735017896 0.2702860533260499 1.0 1.0 0.1887844423268079 0.4819543230991074 diff --git a/protein_atlas_biological_process/metrics.json b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9a42f3ffccdcfe61e1828cf05cd4ebb585d49504 --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 173, + "title": "Average number of proteins per term", + "value": 31.797687861271676 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b7a864f00a815cdb1d8061e36e84cd3bec490f2f --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..70ccbd3ca0794eae1c9695400dec0ca68d77fddc --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,58 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport 0.468334894539518 5.944165537545234 2.7786869144229713e-09 4.80712721493652e-07 4.807128363681742e-07 530 O60830,Q15907,Q9NS69,Q13277,P24390,P05023,P49069,Q99595,Q99584,Q5T8D3,Q9UDW1,P21796,Q567U6,O43731,P00846,O43676,P06576,O14828,O75964,Q13445,Q8N4H5,Q8NE01,P00403,P16615,Q70HW3,Q9H2D1,P45880,Q9UBX3,Q9C0H2,Q6P4Q7,Q9Y282,P51798,O43615,Q2M389,Q9BQE5,P49257,Q14849,P51809,Q92945,O43752,Q9Y487,O95298,Q15629,P50416,Q9Y6M1,Q9Y5L4,Q93050,Q15363,Q6P4A7,Q9H0U3,Q5HYI7,P28288,O14949,O00461,P61421,Q9P2W9,Q9H3N1,Q99808,Q9Y619,O95202,P03886,P22695,Q9C0E2,Q9HD20,O95249,O60831,O15127,Q07955,P56385,O14925,Q8TD16,Q8TB61,P05026,Q9BSK2,O96008,Q96C92,Q6DKK2,Q9H1E5,Q5VZ89,O15027,Q96L92,O43772,Q16629,Q96AA3,O95864,Q9H2V7,P12236,O43169,Q13505,Q9NX14,Q6NUK1,O95197,P51151,Q9Y289,Q9BUN8,Q9Y277,O60749,P41208,Q86Y39,O95168,Q9Y5J9,Q9BTX1,O15504,Q02978,Q96NB2,P14927,P24539,Q9H9B4,Q96QD8,Q15758,O60220,P12235,Q12907,P51148,P61020,Q9Y6M7,Q8NE86,P30825,O60499,Q5JRA6,Q9P253,Q9H0U4,Q9H0H5,P23786,O95070,Q15388,Q8NEW0,O60826,Q96D46,O43674,Q96CU9,Q9BPX6,Q86Y82,O60784,Q9UGP8,Q969Q5,Q96ED9,Q7Z3C6,O15118,Q9Y6C9,Q9BQT8,P20339,P61916,Q8N5M9,P53985,Q92973,Q9BVK6,P31751,Q3ZCQ8,Q7L0J3,Q9Y5X3,Q9NR31,Q8NFH4,P36542,P49755,Q9NZJ7,O43808,Q8N1F7,Q96S66,P08183,O75381,P51790,Q9BRG1,Q9Y3A6,O15498,Q13190,O75438,A6NIH7,O75306,P51572,Q99720,P61019,P31749,P22626,O95721,O43633,Q9H4A6,Q969X5,Q99442,Q9Y5J7,O15126,Q8IXU6,Q9NWR8,P98194,P0CG08,P46379,O75489,Q9H936,O43681,P56134,Q12981,Q9Y3E0 192 +Ion transport 0.6202897493036768 4.021384593848078 5.7857052236487405e-05 0.0099596306874805 0.0005004635018456 58 P56385,P05023,P05026,Q9BPX6,P21796,P00846,P06576,O75964,Q8NE01,P16615,P45880,Q9C0H2,Q6P4Q7,P51798,Q9Y277,Q9Y487,Q9NWR8,P24539,P98194,Q93050,P0CG08,Q96QD8,P61421,P36542,O95202,Q9Y6M7,Q96S66,P56134,Q8NEW0,P51790 30 +Glyoxylate bypass 0.9183190292986094 3.808360560697651 0.0001398911944685 0.0239123288123256 0.0009963454775945 2 P48735 1 +Protein transport 0.4121082608144266 3.4955653243298532 0.0004730586425136 0.0785976800399038 0.0025574732860895 274 O60830,Q15907,Q9NS69,P24390,Q99584,Q99595,Q567U6,O43731,O14828,Q13445,Q8N4H5,O43615,Q2M389,P49257,P51809,O43752,Q15629,Q9Y5L4,Q15363,Q5HYI7,Q9P2W9,Q9C0E2,Q9HD20,O95249,O60831,O15127,O14925,Q8TD16,O96008,Q96C92,Q5VZ89,O15027,Q96L92,Q13505,P51151,Q9BUN8,O60749,P41208,Q9Y5J9,Q9BTX1,O15504,O60220,Q12907,P51148,P61020,O60499,Q5JRA6,Q9P253,Q9H0U4,O95070,Q15388,O60826,Q96D46,Q86Y82,O60784,Q9UGP8,Q969Q5,Q96ED9,P20339,Q8N5M9,Q92973,Q9BVK6,Q3ZCQ8,Q9Y5X3,Q9NR31,Q8NFH4,P49755,Q8N1F7,O75381,Q9BRG1,Q9Y3A6,O15498,A6NIH7,P51572,P61019,O95721,O43633,Q9H4A6,Q99442,Q9Y5J7,O15126,P0CG08,Q9Y3E0 83 +ER-Golgi transport 0.5686346622891879 3.4184751241946305 0.0006297307383555 0.1032496162652754 0.0030262060482088 54 Q9P2W9,P49755,P24390,P49069,O15498,O95197,Q9Y282,O43731,Q15363,O95249,Q9NR31,O95070,P51572,P61019 14 +Translocation 0.5754936780554503 3.284097885089435 0.0010230938147317 0.1622921216382374 0.0043794173845942 50 O60830,Q9BTX1,Q9NS69,O14925,Q15629,Q99595,Q99442,Q3ZCQ8,Q8N1F7,P41208,Q8NFH4,O60220,O75381,Q9Y5J9 14 +Sphingolipid metabolism 0.858642897518045 3.035048018091255 0.0024049739375773 0.3406901033430288 0.0092457886933528 11 O95470,P04062,P17900,P07602,Q16739,Q13510 6 +Neurotransmitter transport 0.802848224473538 2.8991180018349154 0.0037421402849402 0.4772252585279087 0.0129326433593525 3 Q7L0J3 1 +Sugar transport 0.8016577856719884 2.8932717040552403 0.0038125133602715 0.4835750551906158 0.0129326433593525 3 P31749,P31751 2 +Biomineralization 0.7874921585347645 2.823376415194607 0.0047520742761966 0.561356566987702 0.0152242379589261 3 P22413 1 +Hydrogen ion transport 0.6525434301175985 2.795368191909656 0.0051840636465083 0.5930950756407344 0.015734087909578 20 P36542,P24539,P61421,Q93050,P00846,P56134,P06576,O75964,Q9Y487 9 +Neurotransmitter degradation 0.6981355430600811 2.6896456427636335 0.0071527927338999 0.7111592877754291 0.0202857892289292 2 P21964 1 +Sodium/potassium transport 0.7572528123149757 2.6721219659932376 0.0075373247400838 0.729881948558907 0.0206197178621886 3 P05026,P05023 2 +Respiratory chain 0.5513460104712686 2.6525380181329585 0.0079889130572723 0.7503342374079505 0.020940635741032 35 O95298,Q9NX14,O75489,P03886,Q96CU9,Q9UDW1,P22695,Q6DKK2,O95168,O75438,O43676,O75306,Q86Y39,O14949,P00403 15 +Ubiquinone biosynthesis 0.7500048956607674 2.635447723267053 0.0084026367867628 0.7677167774485069 0.0216963606583579 3 Q8NI60 1 +Electron transport 0.511806413367514 2.6172587171768096 0.0088639129682019 0.7856818289545551 0.0222240136738977 48 Q96CU9,Q9UDW1,Q6DKK2,Q9H1E5,O75438,O43676,O75306,P00403,O95864,O43169,Q9NX14,O95168,Q86Y39,O95298,O14949,Q9H3N1,O75489,P03886,P22695 19 +Peroxisome biogenesis 0.8049993766459613 2.5979869841449164 0.0093772048327267 0.8040528772130094 0.0228486821980525 4 Q9Y5Y5,P40855 2 +Apoptosis 0.3871165066924683 2.5415872503770434 0.0110350400310854 0.8533451408789873 0.0261515332243532 130 Q96KA5,O14737,Q13232,P21796,Q15375,Q9UDX5,Q9H2J4,O00571,P61289,P06493,P51572,Q9H3K2,P31749,P09601,Q15041,O95197,P05067,O60313,Q9BXK5,Q96TC7,Q96A26,Q6NUQ4,Q5J8M3,P31751,P10909,Q07812,O95831,Q01085,O43464,O95470,Q9NR28,P46379,P31483,Q9NZJ7,Q07820,Q13501,O14681,Q9UHX1,Q9NQ88,Q12981,P52756 41 +Phospholipid metabolism 0.6613956063388174 2.40608901987496 0.0161243350921209 0.9399299670510328 0.0363655544917023 16 Q9UG56,P35790,Q9BVG9,Q96N66,Q96JX3,Q9HBU6,Q9HCL2,P48651,O95674,Q9NPH0,Q86UL3 11 +Prostaglandin metabolism 0.6647757405650877 2.1916750367826694 0.0284029794916047 0.993159180060644 0.0592013909885255 3 Q9H7Z7 1 +Phospholipid biosynthesis 0.6383611546515296 2.1760344433811025 0.0295526851706855 0.9944262235345016 0.0603902363491351 15 Q9UG56,P35790,Q9BVG9,Q96N66,Q96JX3,Q9HBU6,Q9HCL2,P48651,O95674,Q86UL3 10 +Sterol metabolism 0.5420095779053911 2.16989906938978 0.0300144928556742 0.9948668086743346 0.0603902363491351 25 O15118,P04062,Q15125,O75845,Q16850,P61916,Q15800,Q15392 8 +Porphyrin biosynthesis 0.7622908903001904 2.1640912456711434 0.0304573472521487 0.9952567382566748 0.0605646100531234 5 P22830 1 +Cholesterol metabolism 0.5248905963181866 2.0100237351585943 0.04442867682626 0.9996149495011994 0.0826468934509999 24 O15118,P04062,Q15125,Q16850,P61916,Q15800,Q15392 7 +Amino-acid transport 0.7284160353796043 1.991772810377696 0.0463959907774111 0.999730427357731 0.0853883660052355 8 Q96NB2,P30825,Q6P4A7,Q9H9B4,Q96QD8 5 +ATP synthesis 0.727176812619356 1.9857123392861844 0.0470652740980741 0.999761259811658 0.0856821055701076 8 P36542,P00846,P56134,P06576,O75964 5 +Calcium transport 0.7262960489308593 1.9814026260720463 0.0475461395071117 0.9997812224613504 0.0856821055701076 8 P16615,Q9NWR8,O95202,P98194,Q9BPX6 5 +Sodium transport 0.7235905083622886 1.9681520619574833 0.0490505441108428 0.99983356826921 0.0874818982595444 8 P05023,Q9Y6M7,P05026,Q9Y289,P54709,Q96QD8 6 +Steroid metabolism 0.5085292757493016 1.9438395846832088 0.0519147985906336 0.9999012369206652 0.0916455117977512 26 O15118,P04062,Q15125,O75845,Q16850,P61916,Q15800,Q15392 8 +Symport 0.6948408551945569 1.9361157867812868 0.052853521443525 0.9999167916782216 0.0923601940376751 9 P53985,Q9Y6M7,Q9H936,Q9Y289,Q96QD8,Q15758 6 +GPI-anchor biosynthesis 0.6847995838815469 1.7920795192159849 0.0731202291001089 0.99999802735535 0.1216326887915273 5 O43292 1 +Inflammatory response 0.6294972221863975 1.7076483579215445 0.0877016097526632 0.9999998730346602 0.1404849859926921 10 Q8IV08 1 +Chemotaxis 0.6132662126147383 1.640770254620263 0.1008451150474998 0.999999989687359 0.1600569257175914 4 P09429,O94813,Q8NHP6 3 +Sterol biosynthesis 0.5505164475025865 1.6309865618639772 0.1028931550595786 0.999999993049093 0.1614680323200888 15 Q15125,O75845,Q16850,Q15800,Q15392 5 +Steroid biosynthesis 0.4862737926885409 1.625776682802656 0.1039971703568494 0.9999999943827604 0.1614680323200888 20 Q53GQ0,Q14739,Q15125,O75845,Q16850,Q9H3P7,Q15800,Q15392 8 +Vision 0.6910314474928029 1.618905679547421 0.1054675586830633 0.999999995772102 0.1614680323200888 6 O60313,P50897,Q6P4Q7,Q9H6K4 4 +Sensory transduction 0.6910314474928025 1.618905679547419 0.1054675586830637 0.999999995772102 0.1614680323200888 6 O60313,P50897,Q6P4Q7,Q9H6K4 4 +Lipid transport 0.4614076028879921 1.5674424516521022 0.1170113077739012 0.99999999955307 0.1760257064772601 26 O15118,Q9H2V7,P61916,Q9BQE5,Q14849 5 +Unfolded protein response 0.6189652802934809 1.541109593727838 0.123290115331504 0.9999999998699616 0.1802182459099315 9 Q15629,Q9BUN8 2 +Lipid metabolism 0.3226390362849162 1.5180803320183174 0.1289941486820462 0.9999999999579616 0.18596656434995 135 P51648,Q15125,O15269,Q16850,Q8N2A8,Q16739,P17900,Q13510,Q9H6V9,O15118,P27544,Q14739,Q9P035,Q86UL3,Q9HBU6,P07602,O15254,Q9NPH0,P61916,O95674,Q15800,Q9UKU0,Q9UG56,Q15067,P04062,Q8NHP8,Q9BVG9,Q99735,Q96JX3,Q9HCL2,Q96G23,Q15392,Q8N2K0,O95470,Q96N66,O75845 36 +Autophagy 0.420559830243391 1.4911720463593057 0.1359163307480058 0.999999999989428 0.1943266547058264 34 O95721,Q9UMX0,P53365,Q13501,Q5T8D3,Q9Y6I9,O14681,Q9NQ88,Q8IXJ6,Q9P253,Q969Q5,Q9H0U4,P51149,Q9BXS4,Q7Z3C6,P13473 16 +Antiport 0.6280737305334912 1.4000228567542492 0.1615064740092799 0.9999999999999416 0.223761864620832 7 O95202,P12236,P51790,P51798 4 +Cholesterol biosynthesis 0.5249428474275715 1.399451449019827 0.161677647847422 0.9999999999999436 0.223761864620832 14 Q15125,Q16850,Q15392,Q15800 4 +Glycogen biosynthesis 0.5944751939120704 1.3425634754203477 0.1794133638332113 0.9999999999999986 0.2443977318357919 5 P31749,P31751 2 +Heme biosynthesis 0.5942907724195199 1.2323675877720528 0.21781180279027 1.0 0.287644594524555 7 P22830,P36551 2 +Notch signaling pathway 0.5589336333324186 1.1336131851388829 0.2569568398382049 1.0 0.3367691916061323 8 Q9UBV2,Q92542,P05067 3 +mRNA capping 0.4140278188813342 1.0031130203819782 0.3158063331776906 1.0 0.3961443578684394 2 Q53F19 1 +Spermatogenesis 0.3916103871581295 0.9900208713086204 0.3221639176341813 1.0 0.4009666025231177 26 Q99598,Q08J23,P46379,Q15019,P54652,Q8N2A8,Q9BY67,Q9H0H5,Q14141,Q9Y2W6,O94901,Q9H6S0 12 +Lipid biosynthesis 0.3334608210013744 0.956639926386608 0.3387490291447308 1.0 0.4127012819861861 55 Q15125,P48651,Q16850,Q9H3P7,Q16739,Q92604,O95864,P27544,Q14739,Q9P035,Q86UL3,Q9HBU6,O95674,O00116,Q15800,Q9UG56,Q9BVG9,Q96JX3,Q9HCL2,Q96G23,Q15392,Q53GQ0,P35790,Q96N66,O75845 25 +Nucleotide metabolism 0.4265779655119499 0.7329061123162762 0.4636156948616885 1.0 0.5419291568315683 13 P00813,Q969T7,Q9H0P0 3 +Potassium transport 0.4974037350778146 0.6974498409849446 0.4855213194092878 1.0 0.5562595248861377 6 P05026,P05023,P54709 3 +Stress response 0.3434227638873748 0.6719191936943554 0.5016351405752331 1.0 0.5709399955231271 30 O95433,P98179,O95197 3 +Immunity 0.2856040886102418 0.5423086597122273 0.5876058910145119 1.0 0.6558439944871648 83 O00584,P46379,P04439,Q13501,Q6P179,Q9NUD5,Q9H1D9,P01889,Q8IV08,P10909,P10321,Q8IXJ6,Q8WXW3,O00571,P23246,Q8N5M9,Q9NZ08,P14174 18 +Meiosis 0.3506456379701937 0.4316413421663882 0.6660021060238006 1.0 0.7292301540640349 17 Q8N2A8,Q9H6S0,O94901,P24941 4 +Cell adhesion 0.2901030942587065 0.2669102968604241 0.7895382284248202 1.0 0.8483857982453037 40 P00813,O00192,Q9BQT9,P05026,Q9Y251,P05067,Q08722,Q14574,Q9BY67,P10586,Q8TAB3 11 +Angiogenesis 0.3233447162916703 0.1414826952525624 0.8874886297142588 1.0 0.9419357849114526 11 P35613 1 +Adaptive immunity 0.2875280770413514 0.0731131320080586 0.9417160917959242 1.0 0.9933956334188712 17 Q6P179,Q9NZ08,P10321,P01889 4 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5e4077a565497f31533b19a3852deaa2c9838aba --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Carnitine biosynthesis", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Cysteine biosynthesis", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyridoxine biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sexual differentiation", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AARSD1", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAM17", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEX1", "API5", "APOBEC3C", "APOL2", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARL8B", "ARMC10", "ARMT1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATG4B", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AUP1", "AURKB", "BABAM1", "BABAM2", "BAG6", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRIX1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1D", "C1QBP", "C2CD2L", "C2CD5", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CBL", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC86", "CCDC93", "CCNA2", "CCNB1", "CCNB2", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP250", "CEP55", "CERS1", "CERS2", "CETN2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLSTN3", "CLTA", "CLTC", "CLU", "CMPK1", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "COG3", "COG7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPZ1", "COQ8A", "COQ9", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREB1", "CREG1", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC22", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DECR1", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPYSL2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DUS3L", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHHADH", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC4", "EMG1", "EML4", "ENO1", "ENO2", "ENPP1", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FAM210B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FNBP1L", "FOXK1", "FOXK2", "FOXRED1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCC2", "GCFC2", "GCN1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGPS1", "GHITM", "GINS3", "GINS4", "GM2A", "GMPS", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPHN", "GPI", "GPKOW", "GPR89B", "GRB2", "GRIPAP1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRA", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGXB4", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK2", "HOXD13", "HPRT1", "HPSE", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INTS13", "INTS3", "INTS7", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BP1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD5", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIF11", "KIF18B", "KIF1B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDLR", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRPPRC", "LRRC8C", "LRRFIP2", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LZTS2", "MACF1", "MAD2L1", "MAGED1", "MAGT1", "MANF", "MAP1S", "MAP2K4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MESD", "MFAP1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MIA3", "MICU1", "MIF", "MINDY3", "MKI67", "MKRN2", "MLEC", "MMS19", "MMS22L", "MOB4", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPHOSPH8", "MPP5", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NACC1", "NAE1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCK1", "NCK2", "NCKAP1", "NCOA5", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NEU1", "NFRKB", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME7", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCDH19", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDS5A", "PDS5B", "PDSS2", "PECR", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4KB", "PIBF1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIN1", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLIN3", "PLK1", "PLRG1", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POP1", "POP4", "PPAT", "PPHLN1", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1R8", "PPP1R9B", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PRAF2", "PRC1", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKAA1", "PRKAG1", "PRKCD", "PRKDC", "PRKRA", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTK7", "PTPMT1", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PWP1", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RANBP6", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RECQL5", "REEP3", "REEP4", "REL", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RICTOR", "RIF1", "RILPL1", "RINT1", "RIOX1", "RIOX2", "RMDN3", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP30", "RPP38", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RTCB", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SATB2", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMG9", "SMN1*", "SMNDC1", "SMU1", "SNAP23", "SNAP29", "SND1", 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setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Primary mitochondrial disease 27 99 3.6622050544332967 0.0002500535745899 27.53640776699029 92.44660194174756 0.9978626953080288 0.3665723479658412 11.863754653333944 10.66022291187525 1.7959996823414457 0.3879563837717744 3.679155758032212e-06 0.0001377367296412 3.352097880901199e-05 1.194345839656391e-05 4.639348594393167e-07 +Mucopolysaccharidosis 3 5 2.601482533470647 0.0092821791700878 2.254854368932039 4.752427184466019 0.4843930061917075 0.2034155563537636 0.9831595235232706 0.7286567852681505 1.626107445717624 0.2463507210616131 0.0432787476847939 1.0 0.1018169846714528 0.0276231155809849 0.00138858926748 +Peroxisome biogenesis disorder 2 5 2.585839564920264 0.0097142134863397 1.651851851851852 3.861728395061729 0.6856113691180296 0.377332469305792 1.1308372415785637 1.3826587289706231 1.0890290969778411 0.2972243077369712 0.0762554308819813 1.0 0.1362380906066266 0.3069124011154697 0.0336357980244025 +Zellweger syndrome 2 5 2.585839564920264 0.0097142134863397 1.6098765432098765 3.62716049382716 0.7426807687470057 0.3606424613798319 1.0776752457840464 1.2498901033843046 1.1146363562001904 0.2942639598749884 0.050899384243609 1.0 0.1105474823156849 0.2541534411772372 0.0181181417645757 +Gangliosidosis 3 5 2.3770231146830976 0.0174529944072436 2.8567961165048543 4.902912621359223 0.2158556094961241 0.1574800557957235 1.2213224676890235 0.2960767122713962 1.9039254823866087 0.2239345049259472 0.0002762961331744 1.0 0.047623940504538 0.0001338651392195 2.661109756617399e-05 +Neurodegeneration 23 138 2.307732074345119 0.0210140429608354 27.95631067961165 134.69660194174756 0.269943056894121 0.615157984625689 9.104465669482156 13.994023970959963 0.954862652984542 0.3632698211987682 1.5843011439283152e-05 0.0542489687014012 0.002386214928727 2.981116145948469e-06 0.0001219418125125 +Ichthyosis 3 10 2.0621382289808947 0.0391945776351325 2.424757281553398 8.70873786407767 0.6701903086786922 0.3798909770564678 1.5631275250389387 1.4270688811262522 1.102920967881483 0.3152318826682235 0.0445840383189574 0.1178616319260966 0.0260710687649276 0.0239571113561098 0.0353483729682259 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..23b6c040fe4d9e08ff282f720f8c565b8bb29253 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 114, + "title": "Average number of proteins per term", + "value": 23.37719298245614 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bdf9767fb66f8ebe2606b31962e7c3630e167aa9 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ffc1a0ee2a4c1fd03aa8e740eb1c8dfd91495b81 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,54 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Gaucher disease 0.9792838117786328 4.092434390315921 4.268680435082217e-05 0.0048545778241139 0.0008308581220892 2 P07602 1 +Leber hereditary optic neuropathy 0.9689257176679492 4.044862123941568 5.235392630065227e-05 0.0059507277011448 0.0008308581220892 2 P00846 1 +Niemann-Pick disease 0.9097366084640428 3.7675590807623056 0.0001648515342331 0.0186191064748244 0.0012528716601721 2 O15118 1 +Neuronal ceroid lipofuscinosis 0.9745411486086462 3.700581393476782 0.0002151060689041 0.024226441927069 0.0014424759914751 3 P50897,O75503 2 +Primary mitochondrial disease 0.4809528997246601 3.6622050544332967 0.0002500535745899 0.0281071061684307 0.0015836726390697 99 Q96CU9,Q6DKK2,Q9Y2R0,P00846,O43676,O75306,Q5XKP0,P00403,Q70HW3,O75880,Q9BQT8,Q9UBX3,Q86Y39,O75208,O60313,P13073,Q8NI60,Q6P4A7,O95831,Q9BUB7,Q8N5M1,O14949,O75489,P03886,P22695,Q9BW92,Q96IX5 27 +Hirschsprung disease 0.8585380290026652 3.5197646965429072 0.0004319298058965 0.0480574903588701 0.0024619998936104 2 P42892 1 +Ehlers-Danlos syndrome 0.8886251432518264 3.309539318051167 0.0009344963995627 0.1010990223026686 0.004842390434098 3 Q8NCH0 1 +Meckel syndrome 0.8008286475288571 3.230942066118492 0.0012338294533236 0.1312878072808412 0.0058606899032872 2 Q15058 1 +Long QT syndrome 0.7342408996744633 2.884149358802852 0.0039247255972927 0.3612863326797695 0.0147610828322563 2 P0DP25 1 +Mucopolysaccharidosis 0.8575716611718265 2.601482533470647 0.0092821791700878 0.6546200222296874 0.0307616760400757 5 P15586,P16278,P54802 3 +Peroxisome biogenesis disorder 0.854078574091715 2.585839564920264 0.0097142134863397 0.671373780908471 0.0307616760400757 5 Q9Y5Y5,P40855 2 +Zellweger syndrome 0.854078574091715 2.585839564920264 0.0097142134863397 0.671373780908471 0.0307616760400757 5 Q9Y5Y5,P40855 2 +Gangliosidosis 0.8080690534267007 2.3770231146830976 0.0174529944072436 0.8656367953946837 0.0510164451904046 5 P07602,P17900,P06865 3 +Neurodegeneration 0.3675904930438088 2.307732074345119 0.0210140429608354 0.9111787898742072 0.0590698080472978 138 P07196,P50897,Q14108,Q13510,P35637,P27544,Q15041,Q8IV08,P05067,Q9Y287,P54802,P04062,O75298,Q8NI60,O95831,Q96D71,O75503,O14773,O43464,Q9H0B6,P03886,Q10713,P06865 23 +Cone-rod dystrophy 0.6605681957078626 2.1691643069938857 0.0300702119020264 0.9692111189788514 0.0797210269030467 3 Q6P4Q7 1 +Rhizomelic chondrodysplasia punctata 0.652327693525513 2.1249132179750636 0.0335938548277825 0.9796668882523882 0.087038623871982 3 O00116 1 +Ichthyosis 0.6957463515453339 2.0621382289808947 0.0391945776351325 0.9895180816564756 0.0992929300090025 10 P51648,Q15125,P04062 3 +Premature ovarian failure 0.5791654335602312 2.0145749609571952 0.0439492032298354 0.9940457053006646 0.1022491666979844 2 Q06787 1 +Cataract 0.506262326006654 1.9582860414206835 0.0501964577824503 0.9971799845971164 0.1144479237439866 27 Q15125,P08670,Q9H6K4,Q15800,Q8N2K0 5 +Amyloidosis 0.715785054383548 1.9425288163737089 0.0520731149281439 0.9977492261474912 0.1156948453114393 5 P03886,P05067 2 +Progressive external ophthalmoplegia 0.6705089273604536 1.9367730852141591 0.0527730873350424 0.9979310057775748 0.1156948453114393 4 P12235,Q13472 2 +Deafness 0.4087356638212631 1.83656770402428 0.0662737386899579 0.9995972538532946 0.1373673856482763 56 Q16740,Q96D09,Q9Y2B2,P51572,Q9BV73,Q9NWM8,Q13868,Q9Y287,O60313,Q9UG56,Q15067,Q96JX3,O95831,O76024,O60220,P49736,Q8N2K0,Q9NR28,O75648 19 +Emery-Dreifuss muscular dystrophy 0.6777476325717974 1.757538936854423 0.0788259911334932 0.999913910331552 0.1576519822669864 5 P50402,Q13642,Q9BTV4 3 +Diabetes mellitus 0.600921681626593 1.5511681890528732 0.1208613833597911 0.9999995806866316 0.233528774627393 10 P03886,P49841,Q5VV42,P31751,P22413,O76024 6 +Bardet-Biedl syndrome 0.5331557134399203 1.4624702535000604 0.1436123900391819 0.9999999788931806 0.2683903682699465 3 Q2M1P5,Q9NQ48 2 +Cockayne syndrome 0.4717372003551429 1.362344351107153 0.173089237048075 0.9999999996106992 0.3132090956108023 2 P18074 1 +Xeroderma pigmentosum 0.4717372003551429 1.362344351107153 0.173089237048075 0.9999999996106992 0.3132090956108023 2 P18074 1 +Alzheimer disease 0.5898475313083091 1.3192036235914313 0.1871010472050511 0.999999999944516 0.3332737403339974 5 P03886 1 +Dystroglycanopathy 0.5617602715338629 1.1770980997984115 0.2391563534611662 0.9999999999999708 0.4009385925672493 5 Q9H9S5,O43505 2 +Congenital disorder of glycosylation 0.4451688571171013 1.1458326554171885 0.2518644005670452 0.9999999999999956 0.4161237922412051 18 P46977,O60762,Q8TCJ2,Q8N511,P51571,Q9HC07,Q9BT22,Q9H0U3 8 +FDA approved drug targets 0.3037349054371268 1.1301093990965605 0.2584301297112901 0.9999999999999984 0.4208719255298153 123 P00813,P28074,P05023,P49069,Q8N0U8,P20618,P35610,Q16850,Q16739,O75874,Q99720,P16615,O95864,P12236,P05067,P48735,Q9Y2I1,Q14534,O75116,P50416,P38435,P98194,Q7L0J3,Q96QD8,Q15758,P12235,P48637,P03886,P00374,P23786,P10253,Q13423,P49721,P27361 34 +Retinitis pigmentosa 0.4528765433798976 0.9979653613728962 0.3182961555270502 1.0 0.4816817459421832 15 P00846,Q8IY17,Q96S66,Q8N2K0 4 +Neuropathy 0.3402125431397965 0.992156550564531 0.3211211639614555 1.0 0.4816817459421832 53 P07196,Q15067,Q9H0B6,O15269,P00846,O95831,Q71SY5,Q96BR5,P54802,Q8N2K0 10 +Congenital muscular dystrophy 0.5523057728022736 0.9561715601472308 0.3389855658094274 1.0 0.5018747337957756 6 Q9H9S5,O43505 2 +Spinocerebellar ataxia 0.4852445501738861 0.905611628011611 0.3651414519549791 1.0 0.5205096913522862 10 Q8IV08 1 +Parkinson disease 0.5284986843041679 0.9053689512892168 0.3652699588437096 1.0 0.5205096913522862 7 P04062 1 +Hereditary spastic paraplegia 0.4355111578426004 0.8847142160512114 0.3763107863779118 1.0 0.5231637761839262 15 Q15041,O75298 2 +Parkinsonism 0.4821102232330794 0.8088809489395782 0.4185836281254165 1.0 0.568077781027351 9 P04062 1 +Amyotrophic lateral sclerosis 0.4206889517186851 0.7403948074591244 0.4590604686226354 1.0 0.6156810990938875 14 Q13501,P35637,Q99720 3 +Proto-oncogene 0.3300404439554573 0.7235996438943267 0.4693115600890576 1.0 0.6182643896382153 46 P31749,Q16204,Q92804,Q8WY22,Q01105,P31751,Q01844,Q9NZQ3,P35637 9 +Cushing syndrome 0.4023090586145628 0.7152973149658227 0.4744253473357367 1.0 0.6182643896382153 3 O00170,P10644 2 +Cardiomyopathy 0.354042004033165 0.7096259969886239 0.4779360939309534 1.0 0.6182643896382153 28 O60313,P12235,Q9NX14,P09493,O95677,Q9BTV4,Q53H12,Q9H9S5,P00846,P50402 10 +Joubert syndrome 0.4617019348188327 0.6770048236833901 0.4984028938602733 1.0 0.6313103322230129 5 Q8WXW3,Q7Z4L5 2 +Lissencephaly 0.4201333527353929 0.6224354260401671 0.5336555920750947 1.0 0.6595322551198824 11 Q00535,Q9Y320,Q9H9S5,O43505,P07942 5 +Epilepsy 0.2829323341591613 0.6157803905289124 0.5380394712820094 1.0 0.6595322551198824 71 Q14108,P27544,O43464,P03886,O75503,O14773,Q13510 7 +Osteogenesis imperfecta 0.4373375715997373 0.5767443483940952 0.5641121689087267 1.0 0.6806872766687906 9 O75718,Q14696,Q32P28 3 +Limb-girdle muscular dystrophy 0.3965594061176805 0.378873858844188 0.7047815371819497 1.0 0.7954959924627947 9 O14979 1 +Craniosynostosis 0.3923047226753938 0.3609266521093123 0.7181542791335853 1.0 0.8005806093630587 5 Q9ULC3,P16435,P07237 3 +Hereditary hemolytic anemia 0.3515415809571975 0.3309915008274781 0.7406509054252157 1.0 0.8048197531332174 14 P00813,P48637 2 +Ciliopathy 0.3460390818831537 0.3012241193895698 0.7632435988438 1.0 0.8208468893225773 14 Q9UBB4,O43924,Q7Z4L5,Q15058,Q8WXW3,Q8NCM8 6 +Dystonia 0.3777765907325952 0.2039354392282664 0.8384039504975265 1.0 0.8768628473093396 6 P51572,O60220 2 +Charcot-Marie-Tooth disease 0.2887586617676142 0.1735058620518833 0.8622538205132089 1.0 0.8936085048955074 27 P07196,O95831,P54802 3 +Dwarfism 0.2678344194232441 0.1561169099683787 0.8759408695644586 1.0 0.8996149471202548 51 Q9UG56,O75718,Q32P28,Q14739,Q15125,Q8WVQ1,P48651,Q96HY6,O95831,Q7RTS9 10 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..aef6c9dbecf7e6e471d69436de80e83ff430ce30 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABAT", "ABCB1", "ABCB7", "ABCC1", "ABCD4", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM9", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKAP9", "AKR1B1", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "AMPD2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA7", "AP1B1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APEX1", "APOL2", "APP", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ASAH1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATPAF2", "ATRX", "ATXN10", "AURKB", "B4GAT1", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BMS1", "BPTF", "BRCA1", "BRD3", "BRD4", "BRD7", "BRI3BP", "BUB1B", "BUD23", "C19orf70", "C1QBP", "C3orf58", "CAD", "CADM1", "CALM3", "CALR", "CAMK2G", "CAMLG", "CANT1", "CANX", "CAPN1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBX2", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC6", "CCDC8", "CCNA2", "CCNB1", "CCNB2", "CCT5", "CDC20", "CDC27", "CDC34", "CDC37", "CDC42", "CDC45", "CDC6", "CDC73", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CEP135", "CEP250", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHMP4B", "CHP1", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CLU", "CNNM4", "CNOT1", "CNOT2", "COA3", "COA7", "COG7", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COQ8B", "COQ9", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CREB1", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTH", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBN1", "DBT", "DCPS", "DCTN1", "DCUN1D1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIS3", "DKC1", "DLD", "DLST", "DNAAF5", "DNAJB1", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGFR", "EHHADH", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENO2", "ENPP1", "EPB41", "EPB41L3", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXOSC2", "EXOSC3", "EXOSC9", "EYA4", "EZH2", "EZR", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FAM210B", "FAM3C", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GDAP1", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GGPS1", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI3", "GNE", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOT1", "GOT2", "GPAA1", "GPHN", "GPI", "GPRASP2", "GRB2", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMGXB4", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOXD13", "HPRT1", "HPS3", "HPS6", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT52", "IGBP1", "IGF2R", "IGHMBP2", "ILF3", "ILK", "IMPAD1", "IMPDH2", "INF2", "INTS1", "INTS12", "IPO7", "IRF2BPL", "IRS4", "ITGB1", "ITM2B", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KLC2", "KMT2A", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LGMN", "LIPA", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRP1", "LRP2", "LRPPRC", "LRSAM1", "LSS", "LTA4H", "LYN", "LZTFL1", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MARK3", "MARS", "MATR3", "MBD1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED12", "MED17", "MED23", "MED25", "MEN1", "MESD", "MGME1", "MICU1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MOGS", "MORC2", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTHFS", "MTM1", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MYH10", "MYH14", "MYH9", "MYO1E", "MYO6", "NAA10", "NAA15", "NACC1", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPH", "NCKIPSD", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA6", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NEU1", "NF2", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NME2", "NNT", "NONO", "NOP56", "NPC1", "NPC2", "NPM1", "NRP1", "NSD1", "NSD2", "NSDHL", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B2", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCDH19", "PCM1", "PCNA", "PDAP1", "PDCD4", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDP1", "PDSS2", "PDXK", "PEPD", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIN1", "PINX1", "PISD", "PKM", "PKP2", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POMGNT2", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PRC1", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PTDSS1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "RAB10", "RAB11B", "RAB18", "RAB23", "RAB3GAP2", "RAB7A", "RAB8A", "RABEP1", "RAC1", "RAD21", "RAD23B", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBMX", "RBPJ", "RDH11", "RDX", "RECQL4", "REL", "REPS1", "RFC1", "RFC2", "RFT1", "RHEB", "RHOA", "RINT1", "RNASEH2A", "RNASET2", "ROCK1", "ROCK2", "RP2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS26", "RPS28", "RPS29", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRM1", "RRM2", "RTN2", "RTN4IP1", "RXRB", "SAMHD1", "SAR1B", "SARS", "SART1", "SASS6", "SATB2", "SBDS", "SC5D", "SCARB2", "SCO1", "SCO2", "SCRIB", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC63", "SEPT2", "SEPT9", "SERAC1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SHOC2", "SIGMAR1", "SIN3A", "SIRT2", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC38A2", "SLC3A2", "SLC5A6", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SNAP29", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOAT1", "SOD2", "SON", "SORD", "SPART", "SPATA5", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRP54", "SRP72", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD3", "STAT1", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STX5", "SUCLA2", "SUCLG1", "SUZ12", "SV2A", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBCD", "TBCE", "TBL2", "TCEA1", "TCF20", "TCOF1", "TDP2", "TECR", "TELO2", "TENM3", "TFAM", "TFG", "TFRC", "THG1L", "THOC2", "THOC6", "TIA1", "TIMM17A", "TIMM50", "TIMM8A", "TIMMDC1", "TJP2", "TK1", "TKT", "TMCO1", "TMEM165", "TMEM199", "TMEM38B", "TMEM43", "TMEM70", "TMF1", "TMLHE", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TP53", "TP53BP1", "TP53BP2", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TPX2", "TRAPPC11", "TRIM24", "TRIM25", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMU", "TRRAP", "TSC2", "TSFM", "TSG101", "TSR2", "TTC19", "TTC21B", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWNK", "TXLNA", "TXNRD1", "TYMS", "U2AF1", "UBA1", "UBA5", "UBE2N", "UBE3A", "UBQLN4", "UBR5", "UBTF", "UFSP2", "UGCG", "UGDH", "UGP2", "UMPS", "UPF3B", "UQCC2", "UQCRB", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP9X", "UTP4", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS13A", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WBP2", "WDR1", "WDR11", "WDR26", "WDR36", "WDR45B", "WDR5", "WDR73", "WFS1", "WNK1", "WRAP53", "XPNPEP3", "XPO1", "XRCC1", "XRCC5", "XRCC6", "XRN1", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H14", "ZCCHC8", "ZMPSTE24", "ZMYM2"], "leading_proteins": ["ABHD12", "ACOX1", "ADA", "AGK", "AGPS", "AIFM1", "AIP", "AKT1", "AKT2", "ALDH3A2", "ALG1", "APP", "ARL6IP1", "ASAH1", "ATP1A1", "ATP2A2", "ATP2C1", "ATP6", "ATPAF2", "ATXN10", "B4GAT1", "BCAP31", "BRI3BP", "C19orf70", "CALM3", "CAMLG", "CANT1", "CCDC6", "CDK5", "CDKAL1", "CEP250", "CERS1", "CHST14", "CLCC1", "CLN5", "CLPP", "CNNM4", "COA3", "COA7", "COQ8A", "COQ9", "COX2", "COX4I1", "CPT1A", "CPT2", "CRTAP", "CYP51A1", "DDRGK1", "DHFR", "DIABLO", "DPM1", "DYM", "DYNC2H1", "EBP", "ECE1", "EMD", "ENPP1", "ERCC2", "EWSR1", "EXOSC2", "EYA4", "FADS2", "FHL1", "FKBP14", "FKRP", "FMR1", "FOXRED1", "FUS", "GAA", "GBA", "GGCX", "GLB1", "GM2A", "GNS", "GPRASP2", "GSK3B", "GSS", "HEXA", "HNRNPDL", "HTRA2", "IDH1", "IDH2", "ITM2B", "KIF14", "KIF7", "KLC2", "LAMB1", "LBR", "LZTFL1", "MAGT1", "MAPK3", "MCM2", "MED25", "MESD", "MSMO1", "NAGLU", "NCKIPSD", "ND1", "NDUFA11", "NDUFB11", "NDUFB3", "NDUFS2", "NDUFS3", "NEFL", "NISCH", "NNT", "NPC1", "OPA1", "OPA3", "P3H1", "P4HB", "PDE6D", "PEX16", "PEX19", "PIBF1", "PIGL", "PISD", "PLD3", "PMPCA", "PNPLA6", "POR", "PPT1", "PRKAR1A", "PSAP", "PSMB1", "PSMB2", "PSMB5", "PTDSS1", "RAB23", "REPS1", "ROCK2", "RTN2", "SCARB2", "SCO1", "SERAC1", "SET", "SFXN4", "SIGMAR1", "SLC1A5", "SLC25A10", "SLC25A21", "SLC25A26", "SLC25A4", "SLC25A6", "SLC38A2", "SOAT1", "SPTLC1", "SQLE", "SQSTM1", "SSR4", "STT3A", "STT3B", "SV2A", "TAF15", "TARS2", "TIMM8A", "TMEM165", "TMEM199", "TMEM43", "TMEM70", "TMX2", "TOP3A", "TPM1", "TPP1", "TRMU", "TTC19", "TTC21B", "UGCG", "UQCRC2", "UQCRQ", "USMG5", "VIM", "VKORC1L1", "WFS1"]} \ No newline at end of file diff --git a/protein_atlas_molecular_function/advanced/idx2term.json b/protein_atlas_molecular_function/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..7924ae201680d012c640235dee4dd3d5a1a2a096 --- /dev/null +++ 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sha256:1cd876d5c24252dc5ad2850fd9cf5df6eebcef56ef6cf565ff8a5280028bd196 +size 145937 diff --git a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..821094449f9c69b79b2041df9e4b402fe96bbc30 --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f846c4a4b11def3bed197af3595b157406f029822cc7004dab6eceedd2771f69 +size 91623 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3322aa2c4da0cb105efd026c49ede8b994835869 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Receptor 17 43 3.6967707330604735 0.0002183593751956 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.0455274332626317 0.0011827834234302 0.0107735378474413 0.0810284687722691 0.1594330425111616 +Glycosidase 12 22 3.3427902616230947 0.0008294056253181 7.798543689320389 18.135922330097088 0.5112745472223946 0.1951515073440806 2.9064203812520417 1.9684331341643595 1.9501681029822375 0.2619382904734375 4.18939332358883e-05 1.0 0.0082729445560879 6.706147432458563e-05 6.979772381970834e-08 +Translocase 10 24 2.3034029324246568 0.0212561829173381 8.031553398058252 23.23543689320388 0.8266305625937611 0.3429767730570308 3.903132239147793 3.2553774114037415 1.2917497354360188 0.3272657999875639 0.112911215803706 0.2516504230112798 0.4440833899821513 0.0564393829037643 0.0081716861037673 +Carboxypeptidase 3 6 2.192788024889306 0.0283226551292419 3.1359223300970873 6.150485436893204 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0000000000000000000000000000000000000000..4f3c01213e48eeb3ebe16e74cf7046228215f85e --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 97, + "title": "Average number of proteins per term", + "value": 40.95876288659794 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..fe90c299e2c3b95c25c113bfdb013a07c85e6850 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..755414ec78d3334adde09dafef394a3382e92d40 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,29 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Receptor 0.6587910917976552 3.6967707330604735 0.0002183593751956 0.0209603847453926 0.0023534288215531 43 O15118,Q9NS69,P24390,Q14108,O00264,Q9Y5M8,Q14739,O15173,P35613,P30825,Q15375,O43731,Q9UBG0,O15031,Q8WTV0,P10586,Q99720 17 +Monooxygenase 0.9058614564831252 3.3895318237091168 0.0007001208196986 0.0656792682451578 0.0061737926827968 3 Q16850,Q6UW02 2 +Glycosidase 0.7267960705579891 3.3427902616230947 0.0008294056253181 0.0773319281264122 0.006547287026745 22 P04062,P33908,P04066,Q8IW92,O60502,P10253,O60476,Q9BTY2,P06865,P16278,P54802,P06280 12 +Threonine protease 0.8277934748260662 3.0206575627601797 0.0025222643836846 0.2172709730407417 0.0144581132725138 3 P28072 1 +Porin 0.8762709104185928 2.928480630424927 0.0034062305504045 0.2817721074570545 0.018355797966069 4 P45880,P21796 2 +Cytokine 0.83876285817001 2.756223383887386 0.00584730477423 0.4338257115306178 0.0257812983227414 4 P14174 1 +Calcium channel 0.6463450725066637 2.402301600011877 0.0162922696305993 0.7967595380032617 0.0526783384722713 2 Q8NE86 1 +Translocase 0.5642030485313931 2.3034029324246568 0.0212561829173381 0.8755783201871185 0.0665112820316708 24 P05023,O75489,P03886,P98194,Q9HD20,Q13423,P06576,O75306,P08183,P00403 10 +Carboxypeptidase 0.8162606105951786 2.192788024889306 0.0283226551292419 0.9383913808529596 0.0858530483605145 6 P10619,Q9HB40,P42785 3 +Glycosyltransferase 0.4826635711378883 2.083471325948547 0.0372082827280741 0.9747281223919256 0.1061530419006822 36 P46977,O60762,Q10472,P04062,Q16880,Q13126,O43505,Q68CQ7,Q9BT22,Q16739,Q9Y2G5,P43490,Q06203 13 +Host cell receptor for virus entry 0.5841068785569089 2.0150401106169245 0.0439004465029904 0.987152986175524 0.1203760456569859 17 O15118,Q14108,P35613,P11279,P06493,Q8WTV0 6 +Protease 0.3722212361692186 1.7707894962645288 0.0765957132711976 0.9995604452517052 0.1812142484708822 86 P10619,P28074,P07858,P42892,Q92905,P55786,Q9HB40,Q96K76,P67812,Q8TCT9,Q96FZ2,O75844,Q9UIQ6,O14773,O43464,P28072,Q8TCT8,Q9H3G5,P42785 19 +Chloride channel 0.6053587802667255 1.3974132325544624 0.1622893421974125 0.9999999653165764 0.2994480888695137 5 Q9C0H2 1 +Ion channel 0.52135855014628 1.2086143897542416 0.2268110254690047 0.9999999999854216 0.3728927028897197 11 Q8NE86,Q9C0H2,Q4KMQ2,Q96S66,P0CG08 5 +Serine protease 0.5445434009424284 1.143133308401732 0.2529832467842534 0.9999999999994836 0.4066535685263285 9 O14773,O43464,Q4J6C6 3 +Dioxygenase 0.3824140081720824 0.8427860508543682 0.3993481107684793 1.0 0.5380106492297568 21 P13674,Q6PK18,Q32P28,O15460,Q9BV57 5 +Metalloprotease 0.3620975483629958 0.8069268953951333 0.4197086024064598 1.0 0.5576949922387205 29 Q6P179,P42892,Q5JRX3,Q92905,P55786,Q9UIQ6,O75844,P78536,Q9NZ08,O75976 10 +Oxidoreductase 0.2796000794506554 0.7577990236011948 0.4485713069964945 1.0 0.5770921786898021 172 P51648,Q8N0U8,Q96CU9,P30519,Q16850,Q9H9P8,O75874,O75306,Q6ZRP7,P13674,P16435,P36551,P09601,Q14739,O15254,P48735,Q15800,Q14534,Q9BU89,P13073,Q15067,Q32P28,Q9BV57,Q99735,Q8NBX0,Q9UHG3,O95831,Q15392,Q53GQ0,Q6UW02,O15460,O75489,P00374,O75845 34 +Hydrolase 0.249958105760817 0.6433820857816976 0.5199762045963199 1.0 0.6472925626671013 407 P10619,P00813,P50897,P28074,Q9NX62,P07858,P42892,P15586,Q92905,Q8N2A8,Q9BTY2,P55786,Q9HB40,Q13510,P17900,P16278,Q9NUJ1,Q9H6V9,Q9BQG2,Q6P179,P20339,P11117,Q8IV08,Q96K76,Q8WVQ1,O60476,Q9NPH0,Q4J6C6,Q8NHH9,Q9UMR5,Q9NZ08,P54802,P04062,Q8NHP8,Q9H773,P67812,P33908,Q8TCT9,Q96FZ2,O75844,Q9UIQ6,O14773,Q9UNI6,P07099,P33991,O43464,P28072,Q8IWA4,Q8N2K0,Q8TCT8,Q15165,Q14527,O00584,Q86YN1,P61020,Q9Y3B8,P04066,Q8IW92,O60502,P10253,P22413,P06865,Q9H3G5,Q9H0P0,P42785,O94919,P06280 67 +Decarboxylase 0.4737983341163148 0.5898985924802084 0.555258637819001 1.0 0.6762474653550558 6 Q8NBZ7 1 +Heparin-binding 0.4164006697764136 0.4729804530377918 0.6362271248428817 1.0 0.7276629591308524 9 P10586,P05067 2 +Nuclease 0.3094146462701784 0.4572067614532385 0.6475224388913587 1.0 0.7276629591308524 36 Q9Y3B8,O94919,O00584,Q8IV08 4 +Exonuclease 0.3391946603462137 0.4518392763825293 0.6513847725551971 1.0 0.7276629591308524 19 Q8IV08 1 +Lyase 0.296950457375605 0.3514436372930185 0.7252555497734905 1.0 0.7904470598654897 43 A1L0T0,Q9UG56,O95470,O00584,P38435,Q9P035,P22830,Q99735,P61457,Q8NBZ7 10 +Chaperone 0.2551339875701215 0.3252125634500641 0.745020200801342 1.0 0.8029662164192242 106 O95456,Q16543,Q01105,Q9H2J4,Q9UL15,P78318,Q96KC8,O75880,O15212,Q9Y5J7,Q9UHV9,Q9Y5J9,Q9Y5L4,O95433,Q9NPL8,Q99733,P10909,Q8N5M1,O60220,Q96A33,P46379 21 +Rotamase 0.3002496921848439 0.2397831293781612 0.8104983862912536 1.0 0.8453585319381892 23 Q9NWM8,O95302 2 +Endonuclease 0.2700892782052073 0.0318288397397959 0.9746085474968404 1.0 0.9863936535314418 19 O94919,O00584 2 +Voltage-gated channel 0.290977781460747 0.0298023973682831 0.9762246467940044 1.0 0.9863936535314418 5 Q4KMQ2,P0CG08 2 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7725f42f6659db5d636d620744bd5be86a246ba8 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCC1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "AMPD2", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APBB1", "APEH", "APEX1", "APLP2", "APOBEC3C", "APP", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL8B", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATG4B", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATPAF2", "ATRX", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG4", "BAG5", "BAG6", "BANF1", "BAP18", "BAZ1B", "BAZ2A", "BCAT2", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD8", "BSG", "BTF3", "BTRC", "BUB1B", "BUD23", "BZW1", "BZW2", "C12orf43", "C1D", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CAMK1", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX2", "CBX3", "CBX8", "CCAR1", "CCAR2", "CCDC47", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CDC34", "CDC37", "CDC42", "CDC5L", "CDCA7L", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CEP55", "CERS1", "CERS2", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHKA", "CHMP1A", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLU", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPS5", "COQ8A", "COQ8B", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CUL5", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCP1A", "DCP2", "DCPS", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EGFR", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERMP1", "ERO1A", "ERP44", "ESD", "ESPL1", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "F11R", "FADS2", "FAH", "FAHD1", "FAHD2A", "FAM120A", "FAM120B", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCN1", "GDI1", "GDI2", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN3", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD13", "HP1BP3", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INF2", "INTS11", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "LACTB", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC8C", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYN", "LYPLA1", "MACF1", "MAGED1", "MAGED2", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1S", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPK3", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARK3", "MARS", "MAT2A", "MATR3", "MBD1", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METAP1", "METTL13", "METTL15", "MFN1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCAM1", "NCBP3", "NCL", "NCOA5", "ND1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NEU1", "NFRKB", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD7B", "OXSR1", "P3H1", "P3H3", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDP1", "PDSS2", "PDXK", "PEBP1", "PECR", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHC2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PIGK", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R8", "PPP1R9B", "PPP3CA", "PPP4C", "PPP5C", "PPP6C", "PPT1", "PPT2", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REL", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIOX1", "RIOX2", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPP38", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRP1B", "RRP8", "RRP9", "RSF1", "RTCA", "RTCB", "RTRAF", "RUVBL1", "RUVBL2", "RXRB", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SATB2", "SC5D", "SCAF1", "SCAF4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SEC11A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAMBP", "STAT1", "STAU1", "STAU2", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAMM41", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TK1", "TKT", "TMCO1", "TMEM109", "TMEM38B", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSN", "TSNAX", "TST", "TSTA3", "TTF2", "TTK", 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overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 311 614 9.851407453916105 6.759074305220524e-23 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 9.603677220946056e-37 1.3331661152701865e-13 2.343967764498955e-19 1.411695641843366e-34 2.304912607147344e-48 +Transporters 160 389 6.93074520663367 4.186294547430063e-12 108.9004854368932 367.3009708737864 1.469396346451591 0.4764419032567517 40.40141182476491 35.10022679965902 2.352674986871393 0.4490473364946538 8.350903911653037e-12 8.459788983449556e-05 8.601037106537293e-09 2.50289206780477e-10 5.668085460980331e-17 +Predicted secreted proteins 30 66 4.1141331594806525 3.886370569095021e-05 15.29368932038835 51.737864077669904 1.393291060716792 0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 0.0039850889179451 0.1386157823902389 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P00813,P28074,P05023,P49069,Q8N0U8,P20618,P35610,Q16850,Q16739,O75874,Q99720,P16615,O95864,P12236,P05067,P48735,Q9Y2I1,Q14534,O75116,P50416,P38435,P98194,Q7L0J3,Q96QD8,Q15758,P12235,P48637,P03886,P00374,P23786,P10253,Q13423,P49721,P27361 34 +Candidate cardiovascular disease genes 0.4625116066817505 0.9062152971978656 0.3648219078248398 0.9999274218789967 0.4506623567248021 12 P09493,P07858,P10909,P06865 4 +Metabolic proteins 0.256301849600754 0.721817833815756 0.4704064834482806 0.9999984048708424 0.5487249890139858 925 P00813,P50897,Q05086,P05023,Q96PU5,Q15125,Q9UDW1,P20674,P30519,Q15375,P48651,Q9P0J1,P00846,Q9H9P8,Q16739,Q9BT22,O43676,Q13011,Q13510,O75964,P00403,P13674,Q70HW3,Q9H2D1,P09601,P22830,Q9UBX3,Q8IV08,Q9HBU6,P07602,O15254,Q9NPH0,Q14849,Q9UMR5,P14174,P54802,Q9Y487,Q9BRR6,P04062,P67812,P33908,Q8NCH0,Q93050,Q9UHG3,O75844,O14773,Q8WTV0,O14949,Q8NBZ7,O95470,Q86YN1,Q9Y619,P03886,P22695,P06865,Q13423,P10619,P51648,O60725,Q8TB61,Q9BWD1,P07858,P56378,P15586,Q16850,Q68CQ7,Q9BTY2,P55786,P43490,P17900,Q9NWM8,P27544,Q9BQG2,Q9H1D9,O95302,Q96K76,Q9Y680,P48735,Q15800,Q86Y39,Q9UKU0,Q9BTX1,P13073,Q15067,P24539,Q8NBX0,Q9HCL2,Q7LGA3,Q96G23,Q9UNI6,P07099,Q96QD8,Q8N2K0,Q9Y6M7,P30825,P04066,O60502,P35269,Q10713,O43292,Q05639,Q8NEW0,Q9UBS8,P06280,O15269,Q8N2A8,O75874,O15118,Q96JJ7,Q9BQT8,Q9P035,P11117,Q6P2P2,O43505,Q14534,Q9UG56,P53985,Q10472,Q9H773,Q9BVG9,Q99735,P31751,P24941,Q9NSD9,Q8NFH4,Q15392,Q15165,Q14527,P46977,P36542,P48637,Q96N66,P00374,O43808,O75845,P10253,P22413,Q8N1F7,Q9H0P0,P08183,Q9NX62,O15498,P46934,Q86Y07,O75438,O75306,P09669,P16278,P51572,Q86UY6,P31749,P16435,P36551,Q14739,Q8WVQ1,Q86UL3,O60476,O95674,P0DP25,P51571,Q9BV57,P98194,P61457,P08236,P10586,Q9NQZ5,Q53GQ0,O15460,O75489,Q9H936,P53701,O95747,P04843,P56134,Q96IX5 175 +Disease related genes 0.248033711359055 0.6800615861442139 0.496465466250749 0.9999994471408766 0.5487249890139858 1082 P00813,Q15907,P50897,Q05086,Q14108,P05023,Q96PU5,Q16740,Q15125,Q5T8D3,P20674,Q9Y2R0,P48651,Q9P0J1,P00846,Q9H9P8,Q9BT22,O43676,Q13510,P00403,Q70HW3,Q9H2D1,P09601,P22830,Q8IV08,P07602,Q2M389,P14174,P54802,Q9Y487,Q9Y5Y5,Q8N511,P04062,Q8NCH0,Q96JX3,Q6P4A7,O95831,O75844,O75503,O14773,P33991,O14949,P98175,O95470,Q9Y619,P03886,P22695,Q9UHX1,Q9HC07,P06865,Q13423,Q9NZQ3,Q7RTS9,P10619,P51648,P07858,P42892,Q6DKK2,P15586,Q86XL3,P17900,P35637,Q9H061,Q9NWM8,P27544,Q15041,P05067,P48735,Q15800,Q86Y39,Q9UKU0,Q9Y287,P13073,Q15067,Q92804,O75298,P38435,Q8NI60,P08670,Q96D71,P07099,O43464,O60220,Q96A33,Q8N2K0,Q9NR28,O00584,Q9H0B6,P04066,Q10713,O43292,Q01844,Q9H6K4,Q05639,O14979,P06280,P07196,P09493,Q96D09,Q96CU9,Q9BPX6,O15269,Q9H9S5,Q96HY6,O75874,P40855,Q5XKP0,O15118,O75718,Q16204,Q9BQT8,P11117,O43505,P61916,Q8N5M9,P50402,P38159,O75208,P53985,Q32P28,P31751,Q3ZCQ8,Q71SY5,Q9NSD9,Q8NFH4,Q15392,P46977,P48637,Q92542,Q96N66,P00374,O75845,O14681,P10253,P22413,Q8N1F7,Q96S66,Q9H0P0,Q9NVI7,Q96BR5,P08183,O95684,O75381,Q9NX62,P61978,P55795,P01889,Q01105,O75306,P16278,P51572,Q99720,P31749,P22626,O95721,O75880,P16435,P36551,Q14739,Q9GZY8,Q8WVQ1,Q969X5,Q14574,Q4J6C6,Q96PC5,P0DP25,O60313,P51571,Q08J23,P10321,P98194,Q86YV9,Q8WXW3,Q9Y4P3,Q16625,P61457,Q9BUB7,P08236,Q8N5M1,P10586,Q96EK5,Q15555,P31483,O15460,O75489,Q13501,Q9H936,Q9BW92,P53701,Q5M775,Q8NDZ4,Q96IX5 192 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2779b8dbac92ad047558b1d858b3dbfee0704818 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C16orf58", "C17orf80", "C19orf25", "C19orf47", "C19orf70", "C1D", "C1QBP", "C1orf123", "C1orf35", "C2CD2L", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC8", "CCDC86", "CCDC93", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDR2L", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP135", "CEP170", "CEP250", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM210B", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNBP4", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN3", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HPS3", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRRFIP2", "LRSAM1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METAP1", "METTL13", "METTL15", "MFAP1", "MFF", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MMS22L", "MOB4", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCK1", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PAWR", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETREG2", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RILPL1", "RINT1", "RIOX1", "RIOX2", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIKE1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM177", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC5", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBLCP1", "UBN2", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "UROD", "USE1", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS52", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WNK1", "WNK3", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["ABCB1", "ABCD3", "ABHD12", "ACAT2", "ACBD5", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL6", "ADA", "ADAM17", "ADI1", "ADPGK", "AGPS", "AHSA1", "AIFM1", "AKT1", "AKT2", "ALDH3A2", "ALG1", "ANKLE2", "ANXA11", "APOL2", "APP", "ARL10", "ARL6IP1", "ARL6IP5", "ARMC10", "ASAH1", "ASNA1", "ATAD3A", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2C1", "ATP5C1", "ATP5F1", "ATP5J2", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATPAF2", "B4GAT1", "BAX", "BCAP31", "BCL2L13", "BNIP1", "BRI3BP", "BSG", "C14orf2", "C16orf58", "C17orf80", "C19orf70", "C3orf58", "C5orf15", "CALM3", "CAMLG", "CANT1", "CCDC47", "CCDC6", "CCDC93", "CD47", "CDC37", "CDK1", "CDK2", "CDS2", "CERS1", "CERS2", "CHST14", "CISD1", "CKAP4", "CLCC1", "CLCN3", "CLCN7", "CLN5", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLSTN3", "CLTA", "CLU", "CNNM3", "CNNM4", "COA3", "COA7", "COQ8A", "COQ9", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7C", "CPD", "CPOX", "CPT1A", "CPT2", "CREG1", "CRTAP", "CTSA", "CTSB", "CTSC", "CUTA", "CYB5B", "CYB5D2", "CYP20A1", "CYP51A1", "DCAKD", "DCTPP1", "DDRGK1", "DDX3X", "DENND4C", "DERL1", "DERL2", "DHCR24", "DHFR", "DIABLO", "DNAJC1", "DOLPP1", "DSC3", "DUSP12", "DYM", "EBP", "ECE1", "ECH1", "EEF1A2", "EEF1E1", "EI24", "EIF3L", "EMC4", "EMC7", "EMD", "ENDOD1", "ENPP1", "EPDR1", "EPHA7", "EPHX1", "ERAP1", "ERAP2", "ERGIC1", "ERGIC3", "ETNK1", "EWSR1", "FADS2", "FAM162A", "FAM177A1", "FAM3C", "FARSB", "FECH", "FGFR1OP", "FKBP14", "FKBP7", "FKBP9", "FKRP", "FOXRED1", "FUCA1", "FUCA2", "FUS", "GAA", "GALNT1", "GBA", "GGCX", "GHITM", "GLA", "GLB1", "GLB1L2", "GLG1", "GLT8D1", "GM2A", "GNS", "GOLGA5", "GOLIM4", "GOLT1B", "GOSR1", "GPAA1", "GPAM", "GPAT4", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GSS", "GTF2F1", "GUSB", "HACD3", "HCCS", "HEXA", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMOX1", "HMOX2", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HPS6", "HS2ST1", "HSD17B12", "HSDL1", "HTRA2", "ICMT", "IDH1", "IDH2", "IGBP1", "IGF2BP2", "IKBIP", "ILVBL", "IMPAD1", "INTS1", "ITM2B", "ITM2C", "JAGN1", "KDELR1", "KDELR3", "KIAA0319L", "KIAA2013", "KIFBP", "KLC2", "L2HGDH", "LAMP1", "LAMP2", "LBR", "LDAH", "LETM1", "LMAN1", "LMF2", "LNPEP", "LPGAT1", "LRRC59", "MAGT1", "MAN1A1", "MAN1A2", "MAPK3", "MAPRE2", "MBOAT7", "MCL1", "MCM4", "MCUB", "MED25", "MESD", "MFF", "MFN1", "MGEA5", "MGST2", "MIA2", 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--- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Endoplasmic reticulum 81 205 5.121846688911289 3.025578437113488e-07 55.37621359223301 196.57766990291265 1.2201083743235763 0.4903523338807414 18.868778270733547 13.264167600850914 1.8573715045605257 0.4308007257692164 1.827848451890745e-14 0.0002296910879912 3.0617233593675024e-05 5.157705775838483e-13 1.4698972062000217e-19 +Golgi apparatus 56 191 4.2526779591995805 2.1122923630656487e-05 46.45873786407767 176.03155339805826 1.3643789213018729 0.3972771337532677 14.511319530749702 26.453870355965975 1.6568954592349954 0.4161874156663988 0.0002605150955425 0.0365017544971104 0.0016154131534538 0.0011650815836158 1.2524450580579945e-05 +Mitochondria 141 428 3.26069323738494 0.0011114020852529 110.1747572815534 400.5485436893204 0.4320244196044261 0.5794127039570083 42.49664228528663 36.15232166758906 2.0400795827803786 0.4211568684384254 2.5030795490588223e-08 7.801795978788482e-06 0.0002088193944705 3.2500354468089134e-08 3.9089693510864806e-10 +Vesicles 96 336 2.945780812769093 0.0032214058820063 63.69174757281554 303.19174757281553 0.3021616120018026 0.6308308858815788 16.21576692438533 35.60761931464484 1.2670437076534344 0.3993041904676221 0.0007519422300924 0.3470286541238945 0.0661935680482281 0.0002209588272038 0.0023242684646049 +Peroxisomes 7 16 2.2018442610998417 0.0276763113703959 5.322815533980583 14.701456310679612 0.4359129333192138 0.4564689114892047 2.679509416580786 1.5010345350043446 1.0794334084892987 0.3191667601086948 0.0255113558567383 1.0 0.1854358412925483 0.0901924811619011 0.0028394369313259 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..77d5a252a2e0e272cbc0d9b500ab78fde037809b --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 158.0909090909091 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..58c9c0a8f6e16d0bb63deb0b342f44a8803155a2 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C314/C314_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2d995f4599df6928b01877a186c721c49b86e9aa --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,14 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Endoplasmic reticulum 0.536399366702657 5.121846688911289 3.0255784371134874e-07 9.98436050887926e-06 9.984408842507508e-06 205 Q00765,Q8N0U8,Q15125,P48651,O43731,Q9BT22,P43307,P13674,O00264,O15260,Q8IV08,P49257,Q14849,Q5BJF2,Q6NUQ4,Q8TCT9,Q14696,Q9P2W9,Q9H3N1,Q14257,P35790,O95470,O60831,O96005,Q96AG4,P51648,Q8TCJ2,Q92791,Q16850,Q8IY17,O15027,Q86XL3,Q5T9L3,Q96KC8,P27544,O43169,Q15041,Q15293,O95197,Q9BUN8,Q96CN7,Q9Y680,Q13438,Q15800,Q70UQ0,Q96G23,Q9NQC3,Q96A33,P67809,O43292,Q9H3G5,Q9GZP9,Q96KA5,O43852,O15269,Q96HY6,Q9P035,P50402,Q99735,P84157,Q9NR31,Q8WUJ1,O75845,O14681,Q96S66,Q9H0P0,Q9H6H4,Q86Y07,P51572,Q99442,O95674,Q8NHH9,Q96PC5,Q86UE4,P51571,P0CG08,O15460,O75915,P04843,Q12981,Q6UW68 81 +Golgi apparatus 0.481615148267214 4.2526779591995805 2.1122923630656487e-05 0.0006968209492914 0.0003485282399058 191 P50897,P24390,Q9NX62,O95456,O00231,Q13190,O60637,Q9H9S5,P80303,Q9HB40,P16278,Q6ZRP7,Q9HD45,Q9H4A5,Q9NWM8,Q9H2V7,O15260,P09601,Q92520,Q6P179,Q8WVQ1,Q9H4A6,O95302,P05067,O60476,Q9NPR9,O15212,Q8IZA0,O43752,Q9Y287,Q8NEY8,A1L0T0,Q9UG56,O43760,Q8IXU6,Q9BV57,P55327,P67812,P33908,Q5VW38,P98194,Q8NCH0,Q93050,Q92896,P10586,O00461,P49755,O60499,O14681,Q9HC07,O95070,Q8NEW0,Q8NC54,O15127,Q7RTS9,O15258 56 +Mitochondria 0.3412790751070427 3.26069323738494 0.0011114020852529 0.0360315035799511 0.0073352537626695 428 O60830,Q9NS69,Q99595,Q16740,Q9Y2R0,Q9UDX5,Q9P0J1,Q9H9P8,Q13011,Q69YU5,P06576,O75964,Q8N4H5,P13674,Q70HW3,Q9H2D1,P45880,Q16540,Q9UBX3,Q8WY22,Q04837,O43615,Q96EY8,P83111,Q14168,O95298,P50416,Q8N2F6,Q9Y5L4,Q9Y512,Q9NPL8,Q96TC7,Q96A26,Q16880,O14734,Q6P4A7,O95831,Q5HYI7,O14949,Q9NVH6,P09622,Q9Y3B8,O95202,P22695,P57105,Q3SXM5,P10606,Q9H3H1,Q13423,Q5T9A4,Q9HCC0,Q96CX2,P56385,O14925,Q9Y394,Q9NVT9,O96008,Q9Y2S7,Q6DKK2,P56378,Q68CQ7,O43772,P52789,Q9NUJ1,P12236,Q8N183,Q9Y2C4,Q9NX14,Q13505,Q6NUK1,O95302,Q5JRX3,Q9Y277,P48735,O95168,Q86Y39,Q9H4I3,P13073,Q96NB2,Q8TAE8,Q8NI60,P24539,Q9HCL2,Q9P015,Q8NBN7,Q7LGA3,Q9H9B4,O43464,O60220,Q9UII2,Q9BRT2,P12235,Q9NR28,Q9H0B6,Q8NE86,O75648,Q9Y4W6,Q10713,O43292,P23786,Q15388,O14548,Q8NBU5,Q96CU9,Q9BPX6,P82933,Q5XKP0,Q9H3K2,Q9NX40,Q9NX63,Q9Y6C9,O75208,Q3ZCQ8,Q8IWA4,Q9NQ50,P00374,Q9NVI7,Q96BR5,Q8IYU8,Q96C01,O15498,O75438,O75306,P09669,P36551,Q9GZY8,Q9Y5J7,Q6UXV4,O60313,Q9BXK5,Q9NWR8,P17152,Q9BUB7,Q9NQZ5,Q9NZ45,O75489,Q07820,Q9H936,P53701,P56134,Q96IX5 141 +Vesicles 0.3675033235405114 2.945780812769093 0.0032214058820063 0.1010051658531646 0.017717732351035 336 Q15907,Q13277,P50897,P24390,P49069,P30519,Q567U6,O14828,Q92564,P13674,P53634,Q99538,O75629,P07602,P49257,O95772,Q14849,P51809,Q9UMR5,Q9Y487,Q93050,Q15363,O14734,Q6P4A7,Q9BSJ5,Q9BSH5,Q8WTV0,Q01085,P13473,Q9NRY5,Q86YN1,O43399,Q9BRV8,Q9NUD5,Q9HD20,Q3SXM5,P06865,P42785,O15127,P10619,O75153,Q8TB61,P07858,Q92791,Q96L92,P17900,Q8N128,Q9HD45,Q9UL15,Q9H2V7,P35613,O95302,P05067,Q96K76,Q9Y287,Q8NBX0,Q96D71,Q8TCT8,P61020,P67809,O60499,P04066,P35269,O95070,P27105,Q9BPZ3,O15118,P20339,Q9NPR9,Q8N5M9,P09496,O60506,Q14534,Q32P28,Q9UEE9,P31751,Q08722,Q9Y5X3,P10253,Q8IW92,P51790,Q9BRG1,P16278,P16435,Q9H4A6,Q969X5,O15126,A1L0T0,Q9NWR8,Q96SK2,P08236,Q5BKZ1,O15460,Q13501,Q5M775,Q9Y3E0 96 +Peroxisomes 0.6280575201899556 2.2018442610998417 0.0276763113703959 0.6039421766545989 0.0784621424955461 16 Q15067,Q5T8D3,O43808,O15254,O00116,P40855,O75381 7 +Lysosomes 0.5959300924853957 1.8388003542858056 0.0659445561391893 0.8947316911504544 0.1450780235062166 14 O15400,Q9UNH7,P51149,Q8IY95,P09496,Q8WTV0,O60749 7 +Intermediate filaments 0.4269434172856712 1.4539625176642257 0.1459566983120119 0.994519295366696 0.2408285522148197 31 P07196,O75718,Q86YN1,P07197,Q3SXM5,Q96K76,P08670 7 +Endosomes 0.5490020798891624 1.424762791349479 0.1542257814019625 0.9960244556259196 0.2423547993459411 12 P51148,Q9UNH7,Q8IY95,P09496,O60749 5 +Nuclear membrane 0.3120681641669472 0.8244883692660301 0.4096621216996707 0.9999999720538842 0.5407540006435654 63 Q9BTX1,Q13277,O15260,Q14739,P67812,Q96G23,Q9H1E5,P56134,Q96SK2,P50402,O94919,Q6UW68,O94901 13 +Focal adhesion sites 0.3523443385307514 0.7218646515960421 0.4703776958606587 0.9999999992221662 0.5970178447462207 29 Q9Y3B8,Q9Y6M7,Q969Q5,P08183,Q9Y487 5 +Centriolar satellite 0.2865614132904767 0.1775591632641765 0.8590691978286009 1.0 0.9775615009773736 29 Q03518,Q15907,P33176,O43169,Q15154,O60784,Q8WXW3,P41208,Q86UY6 9 +Midbody ring 0.3355913344996354 0.0774430539183538 0.9382710915279772 1.0 1.0 6 Q06203 1 +Lipid droplets 0.3146629690622556 0.059625124577577 0.952454207445486 1.0 1.0 9 Q8NBQ5,Q01105 2 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..82abf1af50dd1e312ea6b90fc8c292086e7fc7cd --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABAT", "ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG2", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARVCF", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "BABAM1", "BABAM2", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C16orf58", "C17orf80", "C19orf25", "C19orf47", "C19orf70", "C1D", "C1QBP", "C1orf123", "C1orf35", "C2CD2L", "C2CD5", "C5orf15", "C5orf24", "C5orf51", "C8orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC8", "CCDC86", "CCDC93", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKN2AIP", "CDR2L", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP170", "CEP250", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COQ8B", "COQ9", "CORO1B", "COTL1", "COX4I1", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CREG1", "CRKL", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERH", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM210B", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNBP4", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGPS1", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXIM1", "HGH1", "HGS", "HIBCH", "HINT2", "HINT3", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN3", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HPS3", "HPSE", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IFIT5", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRRFIP2", "LRSAM1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METAP1", "METTL13", "METTL15", "MFAP1", "MFF", "MFN1", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINDY3", "MIOS", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MMS22L", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEFL", "NEFM", "NELFA", "NELFCD", "NELFE", "NEMF", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PAWR", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCDH19", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE4DIP", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGL", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB11B", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCL1", "RCN1", "RCN2", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP4", "REEP5", "REPS1", "RER1", "RETREG2", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RHOT2", "RIC8A", "RICTOR", "RIF1", "RILPL1", "RINT1", "RIOX1", "RIOX2", "RMDN1", "RMDN3", "RNASEH2A", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIKE1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLFN11", "SLIRP", "SLK", "SLMAP", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM11", "TMEM126A", "TMEM165", "TMEM167A", "TMEM177", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM70", "TMEM97", "TMF1", "TMLHE", "TMOD3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC27", "TTC37", "TTC38", "TTC4", "TTC5", "TTF2", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC16", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBN2", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "UROD", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR77", "WDR82", "WIZ", "WLS", "WNK1", "WNK3", "WRAP53", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["ABCB1", "ABHD10", "ACBD5", "ACOT8", "ACOX1", "ACOX3", "ADI1", "AFG3L2", "AGPS", "AIFM1", "AKT2", "ALDH3A2", "ALG1", "ANKLE2", "APOOL", "APP", "ARL6IP1", "ARL6IP5", "ARMC1", "ARMC10", "ATAD1", "ATAD3A", "ATAD3B", "ATL2", "ATP13A1", "ATP2C1", "ATP5B", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATPIF1", "BAG5", "BCAP31", "BCL2L13", "BNIP1", "BRI3BP", "BSG", "C12orf73", "C14orf2", "C17orf80", "C19orf70", "C5orf15", "CALU", "CAMLG", "CANT1", "CCDC47", "CCDC93", "CD47", "CDS2", "CERS1", "CERS2", "CETN2", "CFDP1", "CHCHD3", "CHKA", "CHST14", "CISD1", "CLCC1", "CLCN3", "CLPP", "CLPTM1", "CLPTM1L", "CLTA", "CLUH", "COA3", "COA7", "COQ8A", "COQ9", "COX4I1", "COX5B", "COX6C", "COX7A2L", "CPOX", "CPT1A", "CPT2", "CPVL", "CREG1", "CRTAP", "CTSA", "CTSB", "CTSC", "CYB5B", "CYB5D2", "CYP51A1", "DCUN1D4", "DDRGK1", "DERL1", "DERL2", "DHFR", "DHRS7", "DIABLO", "DLD", "DNAJC1", "DOLPP1", "DYM", "EBP", "ECH1", "EI24", "EMD", "ENDOD1", "ERAP2", "ERGIC1", "EXOG", "FAM114A2", "FAM136A", "FAM162A", "FAM177A1", "FAM3C", "FKBP14", "FKBP7", "FKBP9", "FKRP", "FOXRED1", "FUCA1", "GAA", "GADD45GIP1", "GHITM", "GLB1", "GLB1L2", "GLG1", "GLT8D1", "GM2A", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GPAA1", "GPAM", "GPR107", "GPR108", "GPR89B", "GTF2F1", "GUSB", "HACD3", "HCCS", "HDHD3", "HEXA", "HK2", "HM13", "HMOX1", "HMOX2", "HS2ST1", "HSD17B11", "HSDL1", "HTRA2", "IDH2", "IKBIP", "ILVBL", "IMPAD1", "ISOC1", "ITM2B", "JAGN1", "KCTD12", "KDELR1", "KDELR3", "KIAA0319L", "KIF5B", "KLC2", "L2HGDH", "LACTB", "LAMP2", "LBR", "LETM1", "LGMN", "LMAN1", "LRRC59", "MAN1A1", "MAN1A2", "MCCC2", "MCL1", "MCU", "MCUB", "MESD", "MFF", "MFN1", "MGST2", "MIA2", "MICU1", "MICU2", "MMAB", "MPP2", "MRPL15", "MRPL23", "MRPL40", "MRPS9", "MSMO1", "MTCH2", "MTDH", "MTFP1", "MTX1", "MTX3", "MXRA7", "NAA40", "NDC1", "NDUFA11", "NDUFAF2", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFC2", "NDUFS2", "NDUFS3", "NEFL", "NEFM", "NNT", "NPC1", "NT5C3A", "NUCB2", "OCIAD1", "OPA1", "OS9", "P3H1", "P3H4", "P4HA1", "P4HA2", "PAIP2", "PCM1", "PDP1", "PEX14", "PEX19", "PFDN6", "PGRMC1", "PIBF1", "PISD", "PITRM1", "PLD3", "PMPCA", "PNPLA6", "POLDIP2", "POR", "PPAT", "PPHLN1", "PPT1", "PPT2", "PRAF2", "PRCP", "PSAP", "PSMD11", "PSMG1", "PTDSS1", "PTPRF", "QSOX2", "RAB11B", "RAB24", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RCN1", "RCN2", "RDH13", "REEP4", "REEP5", "REPS1", "RER1", "REXO2", "RMDN3", "RPN1", "RTN3", "RTN4", "SAMM50", "SAR1A", "SC5D", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCCPDH", "SCPEP1", "SEC11A", "SEC16A", "SEC62", "SET", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SIKE1", "SLC25A10", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A6", "SLC30A7", "SLC35B2", "SLC35F2", "SLC4A7", "SNX2", "SNX27", "SNX5", "SNX6", "SPECC1", "SPNS1", "SPPL2A", "SPTLC1", "SQLE", "SQSTM1", "SSBP1", "SSR1", "SSR4", "STARD3", "STARD3NL", "STARD7", "STOM", "STT3B", "STX10", "STX18", "STX3", "STX5", "STX6", "STX7", "SUN1", "SURF4", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAP1", "TIAL1", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM9", "TIMMDC1", "TM9SF3", "TMED10", "TMED2", "TMEM11", "TMEM165", "TMEM192", "TMEM205", "TMEM209", "TMEM214", "TMEM70", "TMEM97", "TMLHE", "TMX1", "TMX4", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TPD52", "TPD52L2", "TRABD", "TRIT1", "TRMU", "TSPAN3", "TTC19", "UGT8", "UQCC2", "UQCRC2", "UQCRQ", "USMG5", "USP47", "VAMP7", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VRK2", "WLS", "YBX1", "YIF1A", "YKT6", "ZCCHC3", "ZNF326"]} \ No newline at end of file