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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Degradation of gli1 by the proteasome 0.6050768886663954 2.7381345603350034 0.0061788788675336 0.999825305846351 0.7768193335675377 42 Q9Y297,P28072,P49721,P60900 4
Asymmetric localization of pcp proteins 0.5895913051067921 2.705192171134958 0.0068264885236293 0.9999296799949856 0.7768193335675377 39 P28072,P49721,P60900,Q14997 4
Degradation of dvl 0.5811320339167049 2.641004215996006 0.0082660690726825 0.9999907175938388 0.7768193335675377 39 P28072,P49721,P60900,Q14997 4
Degradation of axin 0.5730873893281624 2.636234672968984 0.0083831732320993 0.999992128323376 0.7768193335675377 37 P28072,P49721,P60900 3
Runx1 regulates transcription of genes involved in differentiation of hscs 0.5734035207276857 2.5259884976103653 0.0115373258614461 0.9999999078398925 0.7768193335675377 41 P28072,P49721,P60900,Q03164 4
Stabilization of p53 0.5637053941168707 2.5075014607673207 0.0121588079013112 0.9999999616967056 0.7768193335675377 39 P28072,P49721,P60900 3
Regulation of ras by gaps 0.5596928622004731 2.504792860674311 0.0122523125052986 0.999999966438131 0.7768193335675377 38 P28072,P49721,P60900 3
Cross presentation of soluble exogenous antigens endosomes 0.5587629419463966 2.4976014797528485 0.0125036671388423 0.9999999764741048 0.7768193335675377 38 P28072,P49721,P60900 3
Dectin 1 mediated noncanonical nf kb signaling 0.569784906567135 2.4704522170413785 0.0134942345334301 0.9999999942046408 0.7768193335675377 42 Q9Y297,P28072,P49721,P60900 4
Tnfr2 non canonical nf kb pathway 0.569784906567135 2.4704522170413785 0.0134942345334301 0.9999999942046408 0.7768193335675377 42 Q9Y297,P28072,P49721,P60900 4
Regulation of runx3 expression and activity 0.544856641539819 2.446549904631057 0.0144230828713058 0.9999999984441392 0.7768193335675377 36 P49721,P60900 2
Downstream signaling events of b cell receptor bcr 0.5623071441083325 2.357752803620294 0.0183859316348149 0.9999999999943854 0.7768193335675377 44 Q9Y297,P49721,P60900,Q14997,P28072 5
Cellular response to hypoxia 0.5472194641278703 2.3515187297427107 0.0186969483073438 0.9999999999963926 0.7768193335675377 40 P28072,P49721,P60900 3
Cdt1 association with the cdc6 orc origin complex 0.5515214670590651 2.329277931222638 0.0198443467166713 0.9999999999992956 0.7768193335675377 42 P28072,P49721,P60900,Q14997 4
G1 s dna damage checkpoints 0.546308792683542 2.3164542461930133 0.0205334798408927 0.999999999999736 0.7768193335675377 41 P28072,P49721,P60900 3
Pcp ce pathway 0.5609368325410261 2.212106557030677 0.0269593031733461 1.0 0.7768193335675377 49 P49721,P60900,Q14997,P28072,O14641 5
Regulation of plk1 activity at g2 m transition 0.5293491455208423 2.211245238923258 0.0270188592020128 1.0 0.7768193335675377 40 Q9Y297,Q13561,O43805,Q9BV73,Q66GS9,O95067 6
Negative regulation of notch4 signaling 0.5241451418101387 2.1700805476827414 0.0300007445331778 1.0 0.7768193335675377 40 P49721,P60900 2
Metabolism of polyamines 0.5181410861303261 2.150497773700673 0.0315158619044249 1.0 0.7768193335675377 39 P28072,P49721,P60900 3
Transcriptional regulation by runx3 0.5219935298050035 2.125100452552239 0.0335782318325597 1.0 0.7768193335675377 41 P49721,P60900 2
Beta catenin independent wnt signaling 0.5625711445413664 2.093481872471041 0.0363061606073116 1.0 0.7768193335675377 54 P49721,P60900,Q14997,P61586,Q9UBI6,P28072,O14641,Q08209 8
G alpha z signalling events 0.8629684663099992 2.087660588796347 0.0368284623386485 1.0 0.7768193335675377 5 Q9UBI6 1
Hedgehog ligand biogenesis 0.5240980234138679 2.0864456412282335 0.0369382743265269 1.0 0.7768193335675377 43 P28072,P49721,P60900 3
Regulation of pten stability and activity 0.5230161121343143 2.0778802497236524 0.0377203900371152 1.0 0.7768193335675377 43 P28072,P49721,P60900,Q14997 4
Regulation of runx2 expression and activity 0.522623559186849 2.0747710821906606 0.0380077558865115 1.0 0.7768193335675377 43 P28072,P49721,P60900 3
Rac2 gtpase cycle 0.497509331120715 2.070350581075755 0.038419526105641 1.0 0.7768193335675377 36 Q9H0H5,P50402,Q16512,P60953,P46940,Q13505,Q68EM7,Q7L576,Q86Y07,O96013,Q9Y512,P43121,Q9H2K8,Q9NSV4,Q14739 15
Defective cftr causes cystic fibrosis 0.5215339670204243 2.038737229422969 0.04147626000672 1.0 0.7768193335675377 44 P28072,P49721,P60900 3
Degradation of beta catenin by the destruction complex 0.5394747524793678 2.018796506020464 0.0435083743732898 1.0 0.7768193335675377 50 Q9Y297,P28072,P49721,P60900 4
Fceri mediated nf kb activation 0.5222833418683681 2.0174406904691344 0.0436495445344606 1.0 0.7768193335675377 45 Q9Y297,P28072,P49721,P60900 4
G protein beta gamma signalling 0.7834898552422044 2.01719902100387 0.0436747482115766 1.0 0.7768193335675377 7 P31751,P60953,P61586,Q9UBI6 4
Signaling by notch4 0.5151389790562064 2.015353686363912 0.0438676034469698 1.0 0.7768193335675377 43 P49721,P60900 2
Auf1 hnrnp d0 binds and destabilizes mrna 0.5093213867846047 1.996508070301237 0.0458786482010307 1.0 0.7768193335675377 42 P28072,P49721,P60900 3
Hedgehog on state 0.5121320055708136 1.991410681363699 0.0464357559060366 1.0 0.7768193335675377 43 P28072,P49721,P60900 3
Cholesterol biosynthesis 0.7067045217164005 1.9867850683884916 0.0469462199905301 1.0 0.7768193335675377 17 Q15392,Q14739,P48449,Q16850 4
Ca2 pathway 0.8369728351549033 1.984166394511597 0.0472372935051037 1.0 0.7768193335675377 5 Q08209,Q9UBI6 2
Interleukin 1 family signaling 0.5344954986633985 1.9798281797678683 0.0477228387683881 1.0 0.7768193335675377 50 Q9Y297,P49721,P60900,Q14997,P28072,Q9H3S7 6
Signaling by the b cell receptor bcr 0.5261529673541705 1.967298156567968 0.0491488474587211 1.0 0.7768193335675377 48 Q9Y297,P49721,P60900,Q14997,P28072 5
Anchoring of the basal body to the plasma membrane 0.495947338950877 1.9604914392001875 0.0499383776118553 1.0 0.7768193335675377 34 Q13561,Q66GS9,O43805,Q9BV73 4
G beta gamma signalling through pi3kgamma 0.8308983735745328 1.9598323909784 0.0500153839735706 1.0 0.7768193335675377 5 P31751,P61586,Q9UBI6 3
Clec7a dectin 1 signaling 0.5251975293484353 1.9597664223621112 0.050023097541977 1.0 0.7768193335675377 48 Q9Y297,P49721,P60900,Q14997,P28072 5
Rhob gtpase cycle 0.6374513335172126 1.9370192748149329 0.0527429872733256 1.0 0.7768193335675377 23 Q9H0H5,Q16513,Q13464,Q92974,Q92888,Q16512,O75116,Q9H2G2,P41440,P63167,Q9NQW6,P27105,P43121,Q9NSV4 14
Potential therapeutics for sars 0.4771917534260713 1.9339051276630692 0.0531247935676062 1.0 0.7768193335675377 35 Q99720,O75116 2
Scf skp2 mediated degradation of p27 p21 0.5009717421760795 1.9296625383180557 0.0536486645115741 1.0 0.7768193335675377 42 P49721,P60900 2
G alpha 12 13 signalling events 0.7510522501898969 1.9222828835004664 0.0545701725474452 1.0 0.7768193335675377 9 Q13464,Q92974,P63218,O75116,P61586,Q9UBI6 6
Signaling by pdgfr in disease 0.8211783957616567 1.9207792217333397 0.0547595470781709 1.0 0.7768193335675377 5 Q13439 1
Thrombin signalling through proteinase activated receptors pars 0.819944291741834 1.915810771319811 0.0553891862041462 1.0 0.7768193335675377 5 Q9UBI6,P28482,P63218 3
The role of gtse1 in g2 m progression after g2 checkpoint 0.5226582839892303 1.8867992550619503 0.0591873313701518 1.0 0.7768193335675377 50 O95067,P28072,P49721,P60900 4
Abc transporter disorders 0.5051320801752355 1.8810869470200644 0.0599600923121965 1.0 0.7768193335675377 45 P28072,P49721,P60900 3
Recruitment of mitotic centrosome proteins and complexes 0.4741809658400251 1.880657739609446 0.0600184918839978 1.0 0.7768193335675377 36 Q13561,Q66GS9,O43805,Q9BV73 4
Rhoc gtpase cycle 0.49956706242578 1.8728023674019705 0.0610956809596636 1.0 0.7768193335675377 33 Q9H0H5,Q16513,Q13464,Q92888,Q16512,P46940,O75116,P61586,Q9H2G2,P41440,P63167,Q9NQW6,P27105,P42167,P43121,Q9NSV4,Q14739 17
Adp signalling through p2y purinoceptor 12 0.8644130361826066 1.8673111858524487 0.0618581442325383 1.0 0.7768193335675377 4 Q9UBI6 1
Gaba b receptor activation 0.8644130361826066 1.8673111858524487 0.0618581442325383 1.0 0.7768193335675377 4 Q9UBI6 1
Gaba receptor activation 0.8644130361826066 1.8673111858524487 0.0618581442325383 1.0 0.7768193335675377 4 Q9UBI6 1
Cyclin a cdk2 associated events at s phase entry 0.4960945669892645 1.8358213944191697 0.0663840762092795 1.0 0.7940610569346371 44 P28072,P49721,P60900 3
O linked glycosylation 0.7455383763381552 1.834694534894268 0.0665509625081322 1.0 0.7940610569346371 6 Q9Y2G5,Q10471,Q8NAT1 3
Adora2b mediated anti inflammatory cytokines production 0.7302992511562898 1.8297273322036791 0.0672907217168821 1.0 0.7960834535319273 9 Q9UBI6,P16220,P63218 3
Ngf stimulated transcription 0.8357248506721606 1.757070061448671 0.0789058679927006 1.0 0.8271133515643041 4 P16220 1
Tcr signaling 0.5061360093256126 1.756122685181989 0.0790674624190619 1.0 0.8271133515643041 50 Q9Y297,P28072,P49721,P60900 4
Uch proteinases 0.499322793967657 1.7545005982040651 0.0793447674937735 1.0 0.8271133515643041 48 P49721,P60900,Q14997,P28072,Q9Y4E8 5
Sema4d induced cell migration and growth cone collapse 0.722339270098079 1.752208938877373 0.0797378871601144 1.0 0.8271133515643041 7 Q13464,P35579,O75116,P61586,Q7Z406 5
G alpha s signalling events 0.7795705745357373 1.75207749769676 0.0797604829855953 1.0 0.8271133515643041 5 Q9UBI6,P63218 2
Rac3 gtpase cycle 0.4541094806293355 1.7438976728741535 0.0811769345043744 1.0 0.8271133515643041 35 Q9H0H5,P50402,Q16512,P60953,Q68EM7,O15498,Q7L576,Q15758,Q86Y07,O96013,Q9UQB8,P43121,Q9H2K8,Q9NSV4,Q14739 15
Vasopressin regulates renal water homeostasis via aquaporins 0.7767565396006064 1.7405834240954456 0.0817566252584387 1.0 0.8271133515643041 5 Q9UBI6 1
Glucagon signaling in metabolic regulation 0.7767565396006064 1.7405834240954456 0.0817566252584387 1.0 0.8271133515643041 5 Q9UBI6 1
Interleukin 1 signaling 0.4973747923596286 1.738956034987752 0.082042496570081 1.0 0.8271133515643041 48 Q9Y297,P49721,P60900,P28070,Q14997,P61088,P28072,P09429,Q13501,P05067,Q99436 11
Apoptotic factor mediated response 0.7160372303562272 1.7072408276915136 0.08777729931401 1.0 0.8271133515643041 6 Q9BZF9,P28482,Q07812 3
Signal amplification 0.71540886861915 1.704511766159289 0.0882855197780991 1.0 0.8271133515643041 6 Q9UBI6 1
Regulation of hmox1 expression and activity 0.4896221441869876 1.703402317156007 0.0884928043769552 1.0 0.8271133515643041 47 P28072,P49721,P60900 3
Aquaporin mediated transport 0.7132163752422727 1.6949850080453923 0.0900782648134574 1.0 0.8271133515643041 6 Q9UBI6 1
Rhoq gtpase cycle 0.6141904654364287 1.6900403786047116 0.0910202299307507 1.0 0.8271133515643041 21 Q16512,P46940,P60953,Q68EM7,Q9Y6M7,P63167,Q9HD26,Q15758,P27105,O96013,Q9NSV4 11
Aurka activation by tpx2 0.4595216413724571 1.6711151201156418 0.0946989413912648 1.0 0.8428298310704361 34 Q13561,Q66GS9,O43805,Q9BV73 4
C type lectin receptors clrs 0.5014330896024255 1.6669467771990336 0.0955249883643332 1.0 0.8428298310704361 52 Q9Y297,P49721,P60900,Q14997,P28072 5
Constitutive signaling by akt1 e17k in cancer 0.693811105022083 1.6652627842919676 0.0958603398758515 1.0 0.8428298310704361 9 P31751,P49815,P16220,Q6R327 4
Phase i functionalization of compounds 0.6634402547785656 1.6560781270443736 0.0977059982315315 1.0 0.8477833593486057 14 P30837,Q16850,P07099 3
Cd28 dependent pi3k akt signaling 0.8095592871033138 1.6557402035286952 0.097774441873299 1.0 0.8477833593486057 4 Q6R327 1
Transport of inorganic cations anions and amino acids oligopeptides 0.6767055059293428 1.6333198653687488 0.1024017408756132 1.0 0.8735126158939218 11 Q70HW3,Q9Y6M7 2
Sema4d in semaphorin signaling 0.6821893032774884 1.6124641766464751 0.1068609692968227 1.0 0.8800451807084173 9 Q13464,P35579,O75116,P61586,Q7Z406 5
Maturation of sars cov 2 nucleoprotein 0.7420120105830299 1.5978881049962963 0.1100678818043241 1.0 0.8800451807084173 5 P78362,P49841 2
Rhobtb1 gtpase cycle 0.6058095259345382 1.5939530043997236 0.1109465612602109 1.0 0.8800451807084173 20 Q13464,Q9BT78,O43396,O75116,Q9UM54,Q8IYB3,Q5VTR2 7
Glucagon like peptide 1 glp1 regulates insulin secretion 0.6868832993047522 1.5800521371547287 0.1140949270583089 1.0 0.8800451807084173 6 Q9UBI6,P63218 2
Orc1 removal from chromatin 0.4935372909174685 1.578791816907872 0.1143838161900543 1.0 0.8800451807084173 53 P28072,P49721,P60900,Q14997 4
G beta gamma signalling through cdc42 0.7867186530234136 1.566761138275973 0.1171705341642912 1.0 0.8800451807084173 4 P60953,Q9UBI6 2
Glutathione synthesis and recycling 0.783970252179874 1.5560256438633997 0.1197019945861952 1.0 0.8800451807084173 4 P48637,Q96KP4 2
Regulation of mecp2 expression and activity 0.6591427603040563 1.550938324921582 0.1209164648620877 1.0 0.8800451807084173 11 Q14739 1
Apoptotic cleavage of cell adhesion proteins 0.6762496221196753 1.533397008299633 0.1251780654289214 1.0 0.8800451807084173 6 Q16625,Q14126,P15924,Q9UDY2 4
Adherens junctions interactions 0.6687718740187263 1.5322620614717577 0.1254577791371312 1.0 0.8800451807084173 8 Q92692,Q9BY67,P19022,P55196 4
Hs gag degradation 0.7663024166880368 1.4868882491354083 0.1370443283257878 1.0 0.9022397223514564 4 Q9Y251 1
Heparan sulfate heparin hs gag metabolism 0.7147812760542123 1.4851876009102571 0.1374941355957011 1.0 0.9022397223514564 5 Q9Y251,P08236 2
Estrogen dependent nuclear events downstream of esr membrane signaling 0.6613254536879991 1.4821719018543922 0.1382945609200712 1.0 0.9022397223514564 7 P31751,P16220,P28482 3
Rhobtb gtpase cycle 0.4972644271462443 1.4811002718292383 0.13857985545825 1.0 0.9022397223514564 29 Q13464,Q9BT78,Q8IYB3,O43396,O75116,Q13618,P12814,Q7Z6E9,Q9UM54,Q16543,Q5VTR2 11
Myogenesis 0.659205730679982 1.458371392882389 0.1447382014017957 1.0 0.9253282127623949 6 P60953 1
Regulation of localization of foxo transcription factors 0.6550317175307612 1.4540757643958593 0.1459253019596009 1.0 0.9253282127623949 7 P31751 1
Cytochrome c mediated apoptotic response 0.7547982993931868 1.4417711074294233 0.1493669561744164 1.0 0.9253282127623949 4 Q9BZF9,P28482 2
Formation of apoptosome 0.7547982993931868 1.4417711074294233 0.1493669561744164 1.0 0.9253282127623949 4 Q9BZF9,P28482 2
Recruitment of numa to mitotic centrosomes 0.4324002191412766 1.425491304665867 0.1540152318507028 1.0 0.9253282127623949 40 Q13561,Q66GS9,O43805,Q9BV73 4
Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.7500514124717919 1.4231363210431769 0.1546966410586903 1.0 0.9253282127623949 4 P61586 1
Rac1 gtpase cycle 0.4417228695233554 1.4217282393076407 0.1551051588727796 1.0 0.9253282127623949 43 Q9H0H5,P50402,P60953,O96013,Q14739,Q96F07,P46940,P63167,Q15758,Q86Y07,Q9UQB8,Q9H2K8,Q16513,O15498,Q7L576,Q9Y2I1,Q16512,Q68EM7,P43121,Q9NSV4 20
Metabolism of steroids 0.4627364841219122 1.4097947412386815 0.1586002998705944 1.0 0.9381610958447026 50 Q15392,Q14739,P48449,Q16850 4
Tcf dependent signaling in response to wnt 0.5041467901575267 1.3923361682408606 0.1638206239808872 1.0 0.952889962822161 64 Q9Y4A5,P31751,P49721,P60900,Q9Y297,Q14997,P28072,O14641 8
Homology directed repair 0.4394408780714403 1.3767573347003463 0.1685872858166859 1.0 0.9613743089047878 44 Q9NRF9,Q9UQ84,Q92547,P61088,Q9NR33,Q9UGN5,Q9NXR7,Q9UNS1,P41440,P24941,Q9NWV8,Q07864,P35244,P18887,Q9NY27,Q13472 16
Mapk6 mapk4 signaling 0.4548590012390583 1.3721345567553151 0.1700215535396223 1.0 0.9613743089047878 49 P28072,P49721,P60900 3
Cdc42 gtpase cycle 0.4701864330400854 1.3712316334397947 0.1703027599759652 1.0 0.9613743089047878 30 Q9H0H5,P14923,Q16512,P60953,P46940,Q68EM7,P63167,O15498,P27105,O96013,P42167,Q9UQB8,Q9NSV4,Q14739 14
Hdr through mmej alt nhej 0.6319514621882764 1.3656151081052357 0.1720598020198087 1.0 0.9613743089047878 8 P18887,P09874,Q9UGN5,P49916 4
Diseases of dna repair 0.6197862113129028 1.3651770684150066 0.172197403948022 1.0 0.9613743089047878 11 Q9UQ84,P78549 2
Hedgehog off state 0.4755143740374088 1.3614159456551762 0.1733822797842403 1.0 0.9613743089047878 56 Q9Y297,P49721,Q8NCM8,P60900,P28070,Q14997,Q13200,P68371,Q9BUF5,P28072,P49841,Q99436 12
Opioid signalling 0.5700192762408833 1.3547188194719164 0.1755071595585773 1.0 0.9613743089047878 19 Q9UBI6,Q08209,P16220,P63218 4
Dna replication initiation 0.6303325816529668 1.3435362795034629 0.1790983867448377 1.0 0.972612917716685 7 Q9NR33,Q9NRF9 2
Ca dependent events 0.6200224471599013 1.3114427043237102 0.189708239142917 1.0 1.0 8 P16220 1
Negative regulation of fgfr1 signaling 0.6222406362571458 1.2949181329198214 0.1953484724959644 1.0 1.0 6 P28482 1
Negative regulation of fgfr4 signaling 0.6222406362571458 1.2949181329198214 0.1953484724959644 1.0 1.0 6 P28482 1
Negative regulation of fgfr3 signaling 0.6222406362571458 1.2949181329198214 0.1953484724959644 1.0 1.0 6 P28482 1
Spry regulation of fgf signaling 0.6222406362571458 1.2949181329198214 0.1953484724959644 1.0 1.0 6 P28482 1
Negative regulation of fgfr2 signaling 0.6222406362571458 1.2949181329198214 0.1953484724959644 1.0 1.0 6 P28482 1
Ncam signaling for neurite out growth 0.6159516865169016 1.2929469132905822 0.1960294203977128 1.0 1.0 8 O15020,P16220,P28482 3
Advanced glycosylation endproduct receptor signaling 0.6095766934977747 1.2794872776755917 0.2007255168915431 1.0 1.0 9 P28482,P09429,P17931,P05067,P27361 5
Activation of the pre replicative complex 0.5148942882730462 1.270465609189745 0.2039188256141324 1.0 1.0 24 Q9NRF9,Q9NR33,O43913,Q07864,P35244 5
Global genome nucleotide excision repair gg ner 0.4158177662532351 1.2624575211281963 0.206784202390817 1.0 1.0 41 Q9BT78,O96019,Q9NRF9,P61088,Q9NR33,Q9UGN5,P41440,Q07864,P35244,P41208,Q92905,P18887 12
Fc epsilon receptor fceri signaling 0.462620915633768 1.260055660127836 0.2076492839826749 1.0 1.0 56 Q9Y297,P49721,P60900,Q14997,P28072 5
Antigen processing cross presentation 0.4497318785607832 1.2559869752271884 0.209120692413592 1.0 1.0 52 P49721,P60900,Q14997,Q9UIQ6,P28072 5
Adrenaline noradrenaline inhibits insulin secretion 0.8967370135096189 1.2398901213600966 0.2150160382316968 1.0 1.0 3 Q9UBI6 1
Transcriptional regulation by runx2 0.4569311229315562 1.2395396766384252 0.2151457046469413 1.0 1.0 55 P31751,P49721,P60900,P28070,Q14997,Q07812,P28482,P28072,Q99436,P49841,P17931,P27361 12
Pkmts methylate histone lysines 0.5889004144343062 1.2394428144018177 0.2151815541283572 1.0 1.0 12 Q8WTS6,Q03164,Q15047 3
Neurotransmitter release cycle 0.6041118019761813 1.225932219339494 0.2202241829541051 1.0 1.0 7 P80404 1
Copi independent golgi to er retrograde traffic 0.4485078551374321 1.2176766927669371 0.2233468574536705 1.0 1.0 30 Q10472,P20340,P52907,Q13561,P68402,Q10471,P63167,P68371,Q9BUF5,Q9H2M9,Q13885 11
Dna replication pre initiation 0.4873935124929134 1.2172586009170347 0.2235058402600362 1.0 1.0 66 P49721,P60900,Q9NRF9,Q14997,Q9NR33,P28072,P35244 7
Raf independent mapk1 3 activation 0.6457298572870402 1.1976419732409624 0.2310564283206435 1.0 1.0 5 P27361,Q02750,P28482 3
Transcriptional regulation by mecp2 0.5654746231236647 1.1975216342201775 0.2311033003211005 1.0 1.0 15 Q14739 1
Biological oxidations 0.4100475845311483 1.1892253588311492 0.2343509981285185 1.0 1.0 42 Q9NZL9,Q9NX62,P07099,P48637,Q96KP4,Q16850,P30837,O00170,Q99735 9
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.4223851022365239 1.1862658216535946 0.23551733959839 1.0 1.0 32 P31689,P52907,Q13561,O60884,P63167,P68371,Q9BUF5,Q13885 8
Thromboxane signalling through tp receptor 0.8795876387265869 1.1796583594474006 0.2381361217123676 1.0 1.0 3 Q9UBI6 1
Deactivation of the beta catenin transactivating complex 0.5757417881984679 1.1762087713768763 0.2395114602655434 1.0 1.0 12 Q9Y297 1
Hdr through homologous recombination hrr 0.4946375465896376 1.1482634161313283 0.2508598367982846 1.0 1.0 24 Q9UQ84,Q9NRF9,Q92547,P41440,Q9NR33,P35244 6
Transcriptional regulation of granulopoiesis 0.5867434324981172 1.148078890533297 0.2509359977088001 1.0 1.0 7 Q03164 1
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.4258251696528664 1.1399367268108875 0.2543126626727021 1.0 1.0 49 P28072,P49721,P60900 3
Transcriptional regulation by e2f6 0.5833317000156253 1.1328048888910929 0.2572961979507293 1.0 1.0 7 P31350 1
Disassembly of the destruction complex and recruitment of axin to the membrane 0.5805698399156914 1.1322681996447426 0.2575216952948338 1.0 1.0 8 O14641,P49841 2
Gap filling dna repair synthesis and ligation in gg ner 0.5289705734435929 1.1321176422833752 0.257584978653145 1.0 1.0 19 P35244,P18887,P41440,Q9NRF9 4
Smad2 smad3 smad4 heterotrimer regulates transcription 0.6299490122563344 1.1319767591443022 0.2576442054424217 1.0 1.0 5 P50750,P28482 2
Pi3k akt signaling in cancer 0.5445932464043476 1.1192189985101826 0.2630467222962773 1.0 1.0 16 P31751,Q6R327,P49841,P49815,P16220 5
Akt phosphorylates targets in the cytosol 0.5820727254668125 1.1170709343025638 0.2639639969672211 1.0 1.0 6 P31751,P49815 2
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.5697382060519904 1.0832251295442918 0.2787085082006659 1.0 1.0 8 Q07812 1
G2 m dna damage checkpoint 0.3743505724583953 1.078348071584339 0.2808784517150509 1.0 1.0 35 Q9UQ84,Q92547,Q9NXR7,Q9Y3B8,P35244 5
Role of abl in robo slit signaling 0.6593206973637566 1.067052234753514 0.2859482492097513 1.0 1.0 4 O94813,O75122 2
Translesion synthesis by polk 0.5597599731370437 1.0648613415895545 0.2869386813117556 1.0 1.0 10 P41440 1
Resolution of abasic sites ap sites 0.4432793188032762 1.0460048471494428 0.2955587944879436 1.0 1.0 28 Q9NRF9,P41440,Q9NR33,P35244,P18887 5
Signaling by tgf beta receptor complex 0.4845807183119205 1.0415692306864432 0.2976114403698811 1.0 1.0 23 P50750,Q9Y624,P61586,P28482,Q9Y4E8,Q9UPN9 6
Carboxyterminal post translational modifications of tubulin 0.564928825004525 1.041474099870257 0.2976555676379373 1.0 1.0 6 P68371,Q9BUF5,Q14166 3
Gap junction degradation 0.6076448639063116 1.0395324430757282 0.2985571776223374 1.0 1.0 5 Q9UM54,Q96CW1 2
Hur elavl1 binds and stabilizes mrna 0.6065062460155408 1.0348294902344637 0.3007485480494041 1.0 1.0 5 O14980,Q01105,P35658 3
Akt phosphorylates targets in the nucleus 0.8345451784075802 1.0228360377205694 0.3063853757726456 1.0 1.0 3 P16220 1
Abc family proteins mediated transport 0.4275786630326934 1.0105692730686933 0.3122226284732634 1.0 1.0 55 Q9NRK6,P28072,P49721,P60900 4
Egr2 and sox10 mediated initiation of schwann cell myelination 0.5553737717556421 1.0081008343811817 0.3134060571307926 1.0 1.0 7 Q16850 1
Synthesis of pe 0.828613646483765 1.0023911060149595 0.3161547359924233 1.0 1.0 3 Q9HBU6 1
Activation of bad and translocation to mitochondria 0.5482154852897497 0.9978942654022906 0.3183306330414188 1.0 1.0 9 P31751 1
Apc c mediated degradation of cell cycle proteins 0.4346592071761077 0.9736931503391796 0.330208919314428 1.0 1.0 59 Q9Y297,P28072,P49721,P60900 4
Signaling by wnt 0.5169313129094084 0.97114130448892 0.3314779177560085 1.0 1.0 88 Q9Y297,Q9Y4A5,P49721,P60900,Q14997,P31751,P61586,Q9UBI6,P28072,P49841,O14641,Q5T9L3,Q08209 13
Class b 2 secretin family receptors 0.8181818181818141 0.966584579716434 0.3337517463313197 1.0 1.0 3 Q9UBI6,P63218 2
Golgi cisternae pericentriolar stack reorganization 0.5316064665863903 0.9655158613596708 0.3342864953655735 1.0 1.0 12 O95067,Q9H8Y8,Q08379,P28482 4
Circadian clock 0.531516352953856 0.965089500443262 0.3344999854146748 1.0 1.0 12 Q9Y297 1
Regulation of insulin secretion 0.5345432085831388 0.9629339316263568 0.3355806800121659 1.0 1.0 11 Q9UBI6,P46940,P29966,P63218 4
Translation of sars cov 1 structural proteins 0.5456209142217374 0.9568481736074026 0.3386438931190905 1.0 1.0 6 P49841 1
Mapk3 erk1 activation 0.6248372371470241 0.9335438141166156 0.3505392595298526 1.0 1.0 4 P27361,Q02750 2
Rhod gtpase cycle 0.4260596031629027 0.9328564578058 0.35089408647891 1.0 1.0 28 Q9H0H5,P50402,Q68EM7,Q9Y6M7,Q02952,Q86Y07,Q9P2R3,P43121,Q9BX68,Q9NSV4,Q14739 11
Scavenging by class f receptors 0.6222317433529891 0.9235480920563232 0.3557216502959843 1.0 1.0 4 P27797,Q9Y4L1 2
Rhoa gtpase cycle 0.3889852724654303 0.9213302740850235 0.3568780198589178 1.0 1.0 46 Q9H0H5,Q13464,Q15904,Q92974,P42167,Q14739,Q96HY6,Q92888,P46940,O75116,P61586,Q9H2G2,P63167,Q9NQW6,Q16513,O15498,P27105,Q16512,P41440,P43121,Q9NSV4 21
Transport of bile salts and organic acids metal ions and amine compounds 0.6188016970732324 0.9104131394782125 0.3626046708611241 1.0 1.0 4 P35613 1
Processing of dna double strand break ends 0.4044511931576068 0.9093554631984724 0.3631625227584871 1.0 1.0 30 Q9UQ84,Q92547,Q9NXR7,P24941,Q9UNS1,Q9NWV8,P35244,Q9NY27,Q13472 9
Base excision repair 0.3944966503417767 0.9060371927791762 0.3649161668200187 1.0 1.0 31 Q9NRF9,P41440,Q9NR33,P35244,P18887 5
G protein mediated events 0.5219568209180685 0.9044835320254696 0.3657390626912171 1.0 1.0 11 P16220 1
Negative feedback regulation of mapk pathway 0.7974533609712741 0.896090119883973 0.3702046334511444 1.0 1.0 3 P27361,P28482 2
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.522173985392907 0.8919160432432254 0.372437934800943 1.0 1.0 10 P50750,P28482,Q9UPN9 3
Vegfr2 mediated vascular permeability 0.5154127371451269 0.8892798044746321 0.3738527224505719 1.0 1.0 12 Q6R327 1
Miro gtpase cycle 0.611950772891349 0.8842654684912982 0.3765529244252972 1.0 1.0 4 Q8IWA4 1
G alpha i signalling events 0.4486579204925998 0.8747898736195208 0.3816882480795867 1.0 1.0 24 P63218,Q08209,Q9UBI6,P05067,P16220 5
Condensation of prometaphase chromosomes 0.5175749514578833 0.8710179535178778 0.3837443503066025 1.0 1.0 10 O95067,P67870,P19784 3
Slc mediated transmembrane transport 0.4550327434565542 0.870770515332999 0.3838794673047032 1.0 1.0 23 P35613,Q9Y6M7,Q99808,Q70HW3,P30825 5
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.5233171353800773 0.8669060485442905 0.3859934891654455 1.0 1.0 7 Q9UQ84 1
Resolution of d loop structures 0.5233171353800773 0.8669060485442905 0.3859934891654455 1.0 1.0 7 Q9UQ84 1
Termination of translesion dna synthesis 0.4842572061438191 0.8642997951709714 0.3874232226723708 1.0 1.0 18 P35244,P41440,Q9NRF9 3
Signaling by hedgehog 0.4340053243512668 0.8600281910894751 0.3897735027346622 1.0 1.0 64 Q9Y297,P28072,P49721,P60900 4
Signaling by tgfb family members 0.4378106371716473 0.8542109130834289 0.392988137557182 1.0 1.0 25 P50750,Q9Y624,P61586,P28482,Q9Y4E8,P27361,Q9UPN9 7
Rhof gtpase cycle 0.4898616288682529 0.8430464096713118 0.3992024885817282 1.0 1.0 16 Q9Y6M7,Q02952,P80723,P42167,P43121,Q9NSV4 6
Rnd3 gtpase cycle 0.4896541264230111 0.8420196562700284 0.3997769510376561 1.0 1.0 16 O75976,Q9Y2I1,O43396,Q9NNW5,P15924 5
Tp53 regulates transcription of cell cycle genes 0.4795321761453883 0.8400259117266986 0.4008938582945949 1.0 1.0 18 Q9NZN8,Q07812 2
Recognition of dna damage by pcna containing replication complex 0.473171334988431 0.8346963910702855 0.4038886741502738 1.0 1.0 19 P35244,P41440,Q9NRF9 3
Formation of senescence associated heterochromatin foci sahf 0.5114852187227209 0.832482090805642 0.4051368828954114 1.0 1.0 9 P54198,P16403 2
Formation of incision complex in gg ner 0.4939191982874499 0.822020508288967 0.4110652249688038 1.0 1.0 14 P61956,P61088,Q9UGN5,P18074,P35244,P41208,P19447 7
Integrin cell surface interactions 0.5953836971012325 0.8215770737668798 0.411317641890109 1.0 1.0 4 P35613 1
Adp signalling through p2y purinoceptor 1 0.7745955571105769 0.8195754046804384 0.4124581995137686 1.0 1.0 3 Q9UBI6 1
Pcna dependent long patch base excision repair 0.4702285622281491 0.8193691264768314 0.4125758439720195 1.0 1.0 19 P35244,P41440,Q9NRF9 3
O linked glycosylation of mucins 0.594616940991141 0.8186963478021404 0.4129596808788964 1.0 1.0 4 Q10471 1
Wnt mediated activation of dvl 0.7734675747704998 0.8158378707289953 0.4145928702320882 1.0 1.0 3 O14641,P67870 2
Cd28 dependent vav1 pathway 0.5521964397930692 0.8136646562632617 0.415837086916313 1.0 1.0 5 P60953 1
Activation of gene expression by srebf srebp 0.4725927961608986 0.8045938398728762 0.4210540980780002 1.0 1.0 18 P48449,Q16850 2
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.4550162465129478 0.7992484989428145 0.4241463350518741 1.0 1.0 21 P35244,P41440,Q9NRF9 3
Carnitine metabolism 0.54709767104175 0.7933403478032143 0.4275795552614108 1.0 1.0 5 P23786,O43772 2
Sumoylation of transcription factors 0.5860630372062594 0.7866964669298676 0.4314595728070185 1.0 1.0 4 P61956,Q13330 2
Dual incision in tc ner 0.337509779925954 0.7789129575261066 0.4360309905170996 1.0 1.0 35 P23193,Q9NRF9,P41440,Q9NR33,P35244 5
Miscellaneous transport and binding events 0.5036128566005027 0.7760363764988951 0.4377275078595302 1.0 1.0 6 P35612 1
Dual incision in gg ner 0.4374319966693555 0.7713446618584883 0.4405026664078035 1.0 1.0 23 P35244,P41440,Q9NRF9 3
Response of eif2ak4 gcn2 to amino acid deficiency 0.4577095569413735 0.7680655748709007 0.4424482276782204 1.0 1.0 77 P62899,P08243,P18621,P62750,P18124,P61513,P62241,P46779,P46776,P40429,Q9Y3U8,P83731,P27635,P61313,P61254,P62847,P08865,P39023,P46781,P62424,P46778,P36578,P42766,Q07020,P18077,Q02878,P60866,P62906,Q02543,P84098,P62917,P08708,P62910 33
Switching of origins to a post replicative state 0.4117221715331224 0.7605151029918102 0.4469467450082853 1.0 1.0 61 P28072,P49721,P60900,Q14997 4
Dna damage bypass 0.4288529245017573 0.7604380685125364 0.4469927752879226 1.0 1.0 24 P35244,P41440,Q9NRF9 3
Suppression of apoptosis 0.753627480011841 0.7507712639905224 0.452790326206911 1.0 1.0 3 P27361,P28482 2
Translesion synthesis by polh 0.4807571773791564 0.7437032875510141 0.4570560001089827 1.0 1.0 13 P41440 1
Hdr through single strand annealing ssa 0.4707626959737685 0.7302178622341945 0.4652570258511144 1.0 1.0 15 P35244,Q9UQ84 2
Homologous dna pairing and strand exchange 0.4707626959737685 0.7302178622341945 0.4652570258511144 1.0 1.0 15 P35244,Q9UQ84 2
Oncogene induced senescence 0.49202916141869 0.7273621161252435 0.4670041554410722 1.0 1.0 6 P28482 1
Prevention of phagosomal lysosomal fusion 0.7461249566899917 0.7265268126501081 0.46751587646868 1.0 1.0 3 P20339 1
Regulation of cholesterol biosynthesis by srebp srebf 0.4153477570512827 0.722347474803676 0.4700808714908757 1.0 1.0 25 P48449,Q16850 2
Lysosome vesicle biogenesis 0.4760523428149306 0.7221117706005955 0.4702257620183596 1.0 1.0 13 O43633,P51809,O14964,Q00610,P05067,O43747,Q10567 7
Response to elevated platelet cytosolic ca2 0.3401525424337332 0.721879342088222 0.4703686630863606 1.0 1.0 34 Q9Y6I9,O43852,P10909,Q8NBF2,P05067,Q6YHK3 6
Eukaryotic translation elongation 0.4535871028121181 0.7209051132135245 0.4709678966925095 1.0 1.0 78 P62899,P18621,P62750,P18124,P61513,P62241,P46779,P46776,P40429,Q9Y3U8,P83731,P27635,P61313,P61254,P62847,P08865,P39023,P46781,P62424,P46778,P36578,P42766,Q07020,P18077,Q02878,P60866,P62906,Q02543,P84098,P62917,P08708,P62910 32
Translocation of slc2a4 glut4 to the plasma membrane 0.3387625341644613 0.7182067963574464 0.4726297880188417 1.0 1.0 38 P31751,P35579,Q96A65,Q9UIQ6,Q8TAG9,Q9Y3B8,Q9BZE9,P68371,Q9BUF5,O60343 10
Deadenylation of mrna 0.4552159433917355 0.7171986545458434 0.4732515293566355 1.0 1.0 18 Q9NZN8,Q9H074 2
Prostacyclin signalling through prostacyclin receptor 0.9129662522202496 0.713905877323659 0.4752853828240202 1.0 1.0 2 Q9UBI6 1
Glucagon type ligand receptors 0.9129662522202496 0.713905877323659 0.4752853828240202 1.0 1.0 2 Q9UBI6 1
Inwardly rectifying k channels 0.9129662522202496 0.713905877323659 0.4752853828240202 1.0 1.0 2 Q9UBI6 1
Presynaptic function of kainate receptors 0.9129662522202496 0.713905877323659 0.4752853828240202 1.0 1.0 2 Q9UBI6 1
G protein activation 0.9129662522202496 0.713905877323659 0.4752853828240202 1.0 1.0 2 Q9UBI6 1
Potassium channels 0.9129662522202496 0.713905877323659 0.4752853828240202 1.0 1.0 2 Q9UBI6 1
Amino acid transport across the plasma membrane 0.5200257925585563 0.6872804235695779 0.4919060327295352 1.0 1.0 5 P30825 1
Gpcr ligand binding 0.4760697706354995 0.6865854107934692 0.4923440246433772 1.0 1.0 10 P05067,Q9UBI6,P42892,P63218 4
N glycan trimming and elongation in the cis golgi 0.9020130254588428 0.6823076993475169 0.4950444055954288 1.0 1.0 2 P33908 1
Intrinsic pathway for apoptosis 0.4359633317857888 0.6702502409775469 0.5026982813781733 1.0 1.0 20 P31751,Q07812,Q9Y3B8,P28482,P63167,Q9BZF9 6
Tp53 regulates transcription of dna repair genes 0.3602400386394937 0.6695329566481251 0.5031555648900943 1.0 1.0 31 P50750,Q9NYV4,P23193,P35269,P13984,P19387,P18074,Q9Y5B9,Q08945,Q9H3P2 10
Fgfr2 alternative splicing 0.4453355687910317 0.6685119690815157 0.503806844290017 1.0 1.0 18 P35269,P13984,O43251,P19387,P09651,P52597,P31483 7
Initiation of nuclear envelope ne reformation 0.4398057422733268 0.6643993136514227 0.5064347720314766 1.0 1.0 19 Q8IXJ6,Q8NC56,Q86Y07,O95067,Q14739 5
Extra nuclear estrogen signaling 0.4523111876668461 0.661418897470508 0.5083437101862496 1.0 1.0 16 P31751,P63218,P28482,Q9UBI6,O43815,P16220 6
Gap junction assembly 0.5107777502936559 0.6518910485771042 0.5144714599197446 1.0 1.0 5 P68371,Q9BUF5 2
Transport of connexons to the plasma membrane 0.5107777502936559 0.6518910485771042 0.5144714599197446 1.0 1.0 5 P68371,Q9BUF5 2
Mitotic g1 phase and g1 s transition 0.4510031020022788 0.6491931728600624 0.5162135239689789 1.0 1.0 81 P31751,P49721,P60900,Q9NRF9,Q9NR33,P28072,P35244,P31350 8
Foxo mediated transcription 0.4611851929983203 0.642507292714601 0.5205438557452249 1.0 1.0 12 P31751 1
Ovarian tumor domain proteases 0.4643435209300099 0.6285746546877268 0.5296275576533167 1.0 1.0 9 P25054,P61586,Q96FW1 3
Transcriptional regulation by runx1 0.4178149857496537 0.6274297078098958 0.530377599322917 1.0 1.0 70 P49721,P60900,Q14997,Q16625,P28072,Q03164 6
Synthesis of very long chain fatty acyl coas 0.4649267838758395 0.6247532500069816 0.5321330180174619 1.0 1.0 8 Q9P035,Q9NZ01 2
Cell cell junction organization 0.4593153554138442 0.6238551429912954 0.532722721591822 1.0 1.0 11 P19022,P55196,Q8N3R9,Q92692,Q9Y624,Q9BY67 6
Signaling by fgfr 0.391217723937062 0.6233629542310563 0.5330460365078176 1.0 1.0 26 P35269,P13984,O43251,P28482,P19387,P09651,P52597,P27361,P31483 9
Signaling by fgfr2 0.391217723937062 0.6233629542310563 0.5330460365078176 1.0 1.0 26 P35269,P13984,O43251,P28482,P19387,P09651,P52597,P27361,P31483 9
Rab geranylgeranylation 0.4008006208529964 0.6046898769235247 0.5453850756151228 1.0 1.0 24 Q9ULC3,Q9BZG1,P20339 3
Dna double strand break repair 0.3807944204775411 0.602621402368911 0.5467605791535952 1.0 1.0 58 Q9UQ84,Q9NRF9,Q92547,Q9NXR7,Q9NR33,P41440,Q9UNS1,P35244,P18887,Q9NY27 10
Leishmania infection 0.3343279392167551 0.5973117802179891 0.5502992408892284 1.0 1.0 42 Q9NZQ3,Q92747,Q96F07,P63218,P35579,P60953,P28482,Q9UBI6,Q7L576,P05067,P16220,O14641,Q9UQB8,P27361 14
Transcription coupled nucleotide excision repair tc ner 0.3446556387696075 0.5885332929564538 0.5561743938595691 1.0 1.0 46 Q9BT78,P23193,Q9NRF9,Q9NR33,P41440,P35244,P18887 7
Rnd2 gtpase cycle 0.4396059722089536 0.5864753580965602 0.557556116278157 1.0 1.0 15 O43396 1
Retrograde transport at the trans golgi network 0.4230692955655141 0.582609332423241 0.560156321523031 1.0 1.0 19 P20340,Q13439,P40616,P53365,O43752 5
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.4016020411103843 0.5776035809256304 0.5635317887588125 1.0 1.0 23 P35244,P41440,Q9NRF9 3
Nr1h2 and nr1h3 mediated signaling 0.454693132522363 0.5757166502155138 0.5648067192367328 1.0 1.0 6 P28702,Q8NB78,O00767 3
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.4454986109881036 0.5747863764826282 0.565435781569946 1.0 1.0 12 Q9UBI6,P67870,P63218 3
Erbb2 regulates cell motility 0.6914421083802099 0.5572880894788756 0.5773306120601898 1.0 1.0 3 P00533,P61586 2
Transcription of the hiv genome 0.3575587930000729 0.5516760343851806 0.581170332413683 1.0 1.0 29 P50750,P23193,Q15545,P35269,P13984,P29083,P19387,P18074,Q9Y5B9,Q08945,Q9H3P2,P19447 12
Mitotic g2 g2 m phases 0.4735820472868995 0.5435017360606339 0.586784395895734 1.0 1.0 96 Q9Y297,P49721,P60900,Q14997,Q13561,O43805,P28072,Q9BV73,Q66GS9,O95067 10
Signaling by notch3 0.4460273594513929 0.5419483748497249 0.5878540704419224 1.0 1.0 6 P67809 1
Regulation of tp53 expression and degradation 0.435010802335578 0.540815158446855 0.5886349935904118 1.0 1.0 13 P31751,Q6R327 2
Phospholipid metabolism 0.3376782349612249 0.539762270792745 0.5893609895737839 1.0 1.0 46 P35790,Q8IY17,P20339,Q8NCC3,Q9HBU6,O95674,Q96N66 7
G2 m checkpoints 0.4514272226439089 0.5344638250471223 0.5930206710818238 1.0 1.0 88 P49721,P60900,Q14997,Q9UQ84,Q92547,Q9NXR7,Q9Y3B8,P28072,O43913,P35244,O95067 11
Gap junction trafficking and regulation 0.4371731720354318 0.531070020346433 0.5953702582258722 1.0 1.0 11 Q07157,P68371,Q96CW1,Q9BUF5,Q9UM54,Q13885 6
Rhou gtpase cycle 0.4134578816806266 0.5179286666491353 0.6045080401619318 1.0 1.0 18 Q16512,O43396,P46940,P60953,Q9NNW5,Q9UM54,O96013 7
Rho gtpases activate rocks 0.4334893210860938 0.5160838725245582 0.6057958313426042 1.0 1.0 11 Q13464,Q16512,P35579,O75116,P61586,Q7Z406 6
Signaling by activin 0.8401420959147423 0.5133587137290319 0.6077004201099312 1.0 1.0 2 P28482 1
Signaling by nodal 0.8401420959147423 0.5133587137290319 0.6077004201099312 1.0 1.0 2 P28482 1
Cd28 co stimulation 0.4321515843252499 0.5106767677487474 0.6095774111534371 1.0 1.0 11 P31751,Q6R327 2
Hiv transcription elongation 0.3817535094693955 0.5047242406909981 0.6137525328031361 1.0 1.0 24 P50750,P23193,P35269,P13984,P19387,P18074,Q9Y5B9,Q08945,Q9H3P2 9
Signaling by ctnnb1 phospho site mutants 0.4354047099962664 0.5034607562907429 0.6146403648196652 1.0 1.0 7 P49841 1
Beta catenin phosphorylation cascade 0.4354047099962664 0.5034607562907429 0.6146403648196652 1.0 1.0 7 P49841 1
Rho gtpases activate iqgaps 0.4279043761946367 0.5015733491987817 0.6159676701510892 1.0 1.0 12 P68371,Q9BUF5,P60953,Q13885 4
Signaling by notch 0.371058962433505 0.5010179477481724 0.61635849173974 1.0 1.0 60 P28072,P49721,P60900 3
Epha mediated growth cone collapse 0.4310336818356611 0.4994109082077513 0.6174899361111037 1.0 1.0 10 Q13464,P35579,O75116,P61586,Q7Z406 5
Esr mediated signaling 0.3373428636411104 0.4990229024699095 0.6177632497540855 1.0 1.0 48 P50750,P31751,P63218,O14646,P35269,P28482,Q9UBI6,P19387,O43815,P16220 10
Intra golgi traffic 0.4157540694444991 0.4960270369739539 0.619875335550486 1.0 1.0 16 O00461,O43752,P33908 3
Rab gefs exchange gtp for gdp on rabs 0.3478787083269049 0.4949101399837376 0.620663552699595 1.0 1.0 29 P31751,P20340,P20339,Q5VZ89,Q15286,Q9H2M9,Q9Y296,P61106,Q9Y2L5 9
Piwi interacting rna pirna biogenesis 0.4294577194258272 0.4931992438307885 0.6218718121281039 1.0 1.0 10 Q9Y2W6 1
Activation of kainate receptors upon glutamate binding 0.501790001877139 0.4906697703427968 0.6236600305679314 1.0 1.0 4 Q9UBI6 1
Pten regulation 0.3926642737353066 0.4828117942578998 0.6292293756484277 1.0 1.0 69 P31751,P49721,P60900,P28070,Q14997,P67870,Q14839,Q13200,Q12873,P28482,P28072,Q15910,Q99436,P27361 14
Apoptosis induced dna fragmentation 0.4275324055068508 0.4804583871737863 0.630901485797319 1.0 1.0 9 P09429,P26583,P16403 3
Glycerophospholipid biosynthesis 0.3452400121079727 0.4797871313796528 0.6313787642021549 1.0 1.0 29 O95674,Q9HBU6,P35790,Q8NCC3 4
Gpvi mediated activation cascade 0.429232038346486 0.4784032800701285 0.6323631994978363 1.0 1.0 6 P61586 1
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.4285847069118775 0.476008657703409 0.634068209943504 1.0 1.0 6 P31751 1
Insulin receptor signalling cascade 0.4274236012344769 0.4733501225431917 0.635963408167914 1.0 1.0 7 P31751,P28482 2
Hdms demethylate histones 0.4238468181375917 0.466357535702129 0.640959601628452 1.0 1.0 9 P29375,Q9UPP1 2
Negative regulation of the pi3k akt network 0.4116798285941702 0.4657349598278711 0.6414052252016904 1.0 1.0 15 P31751,Q8TBX8,P28482,O43815 4
Complex i biogenesis 0.319410306116982 0.4592772207041648 0.6460351036531515 1.0 1.0 32 O75306 1
Nucleotide excision repair 0.3531506594112819 0.4570934053936812 0.6476039100749282 1.0 1.0 56 Q9BT78,O96019,P23193,Q9NRF9,P61088,Q9NR33,Q9UGN5,P41440,P19387,Q07864,P35244,P41208,Q92905,P18887 14
Srp dependent cotranslational protein targeting to membrane 0.4482017536740847 0.454551956151566 0.6494316053527014 1.0 1.0 92 P62899,P18621,Q15629,P62750,P18124,P61513,P62241,P46779,P46776,P40429,Q9Y3U8,P83731,P27635,P61313,P61254,P62847,P61009,P09132,P04844,O76094,P08865,P39023,P46781,P62424,P46778,P37108,P36578,P42766,Q07020,P18077,Q02878,P60866,P62906,Q02543,P84098,P62753,P62917,P08708,P62910 39
Signaling by vegf 0.3251957521753948 0.4479210469610601 0.6542101781587477 1.0 1.0 31 P31751,Q96F07,P60953,O75116,P61586,Q7L576,Q6R327,Q9UQB8 8
Hiv elongation arrest and recovery 0.3826824341492145 0.4358151152864826 0.6629708761942217 1.0 1.0 21 P50750,P23193,P35269,P13984,P19387,Q9Y5B9,Q9H3P2 7
Metabolism of folate and pterines 0.4127810198167341 0.4249549546834444 0.6708695123579556 1.0 1.0 9 P41440 1
Mrna splicing minor pathway 0.297564939042056 0.4232129127771523 0.6721399264280705 1.0 1.0 34 P62316,O75643,Q8TBF4,P62314,Q13247,P35269,P13984,Q96DI7,P19387,Q13435,Q9BUQ8,Q9BWJ5,P67809,O75533,Q16629 15
Amyloid fiber formation 0.4121328204740653 0.419529860058257 0.6748289367378555 1.0 1.0 8 Q9Y287 1
Dna damage recognition in gg ner 0.3940055837528818 0.4178764671466147 0.676037439093635 1.0 1.0 17 P41208,O96019,Q9BT78,Q9UGN5 4
Inactivation of cdc42 and rac1 0.640313195176292 0.414582685890714 0.67844742516065 1.0 1.0 3 P60953 1
Regulation of mrna stability by proteins that bind au rich elements 0.3728266135012101 0.4117373199768715 0.6805319677495534 1.0 1.0 66 P28072,P49721,P60900 3
Rhov gtpase cycle 0.3922330098761656 0.4105805445282286 0.6813801320732034 1.0 1.0 17 O43396,P60953 2
Activation of the ap 1 family of transcription factors 0.6386603288090567 0.4102787443580344 0.6816014825931034 1.0 1.0 3 P28482 1
Nonsense mediated decay nmd 0.4296439178069881 0.3936962835425575 0.6938052855402748 1.0 1.0 89 P62899,P18621,P62750,P18124,P61513,P62241,P46779,P46776,P40429,Q9Y3U8,P83731,P27635,P61313,Q9BZI7,P61254,P62847,P08865,P39023,P46781,P62424,P46778,P36578,P42766,Q15287,Q07020,P18077,Q02878,P60866,P62906,Q02543,P84098,P62917,P08708,P62910 34
Rho gtpases activate wasps and waves 0.3830944582387801 0.3867310723361353 0.6989553102220438 1.0 1.0 18 Q9NZQ3,Q92747,P60953,P28482,Q7L576,Q9UQB8,P27361 7
Formation of rna pol ii elongation complex 0.3205443106602828 0.3811461469932818 0.7030948067808525 1.0 1.0 30 P50750,P23193,P35269,P13984,P19387,P18074,Q9Y5B9,Q08945,Q9H3P2 9
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.6268877702102391 0.3802488044807546 0.7037607343876355 1.0 1.0 3 P28702,O00767 2
Erks are inactivated 0.3992478415524987 0.3723637363903959 0.7096220499367463 1.0 1.0 6 P28482 1
Signal transduction by l1 0.3958060556481345 0.3718872853781445 0.7099767721025934 1.0 1.0 11 Q16512,P67870,P28482,Q02750,P27361,P19784 6
Nrage signals death through jnk 0.3983828016314663 0.3697943229020956 0.7115357455434559 1.0 1.0 7 Q92974 1
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.6225748380070586 0.3695290379821177 0.7117334331784562 1.0 1.0 3 P18887 1
Endosomal sorting complex required for transport escrt 0.3918199247610275 0.3692549006908886 0.7119377378719145 1.0 1.0 13 Q9BRG1,Q99816 2
Stimuli sensing channels 0.3941950003877483 0.3619691707524539 0.7173750686953977 1.0 1.0 10 P27105,Q9C0H2,Q9BYP7,Q4KMQ2 4
P75ntr regulates axonogenesis 0.6183530616581466 0.35918661541326 0.7194554888078732 1.0 1.0 3 P61586 1
Notch3 activation and transmission of signal to the nucleus 0.6160334821079804 0.3535686159932656 0.7236621977677671 1.0 1.0 3 P67809 1
Hdacs deacetylate histones 0.389009264799549 0.3528498220629338 0.7242010303761104 1.0 1.0 12 Q12873,Q14839,O00422,Q13330 4
Sars cov infections 0.3490876301294433 0.3520846487640068 0.724774780738326 1.0 1.0 61 Q8TBF4,Q99720,O75116,Q12873,P49841 5
Synthesis of dna 0.4137973506675556 0.349863063085158 0.7264414686220826 1.0 1.0 86 P49721,P60900,Q14997,Q9NRF9,P41440,Q9NR33,P28072,O43913,P35244 9
Cell death signalling via nrage nrif and nade 0.3890089594403187 0.3440761948655056 0.7307889848886764 1.0 1.0 10 Q13501,Q92974 2
Binding and uptake of ligands by scavenger receptors 0.3873395466198728 0.3340075519023963 0.7383738600207137 1.0 1.0 8 Q8WTV0 1
Metalloprotease dubs 0.3854492550264768 0.3271404479981565 0.7435616603202599 1.0 1.0 7 Q9NXR7 1
Transmission across chemical synapses 0.3007440529007473 0.3227671549989448 0.7468715892577114 1.0 1.0 45 P35609,P63218,Q14168,P28482,P68371,P80404,Q9BUF5,Q9UBI6,P16220,O75915,P27361,Q13885 12
Ub specific processing proteases 0.3695797592319423 0.3203514518736375 0.7487019235626386 1.0 1.0 71 P49721,P60900,Q14997,P28072,Q9Y4E8 5
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.3804958576517168 0.3188672847813382 0.7498271532991987 1.0 1.0 11 Q03164 1
Signaling by retinoic acid 0.3776020719803298 0.318608575858412 0.7500233495211308 1.0 1.0 13 Q01469 1
Bmal1 clock npas2 activates circadian gene expression 0.6004599143679743 0.3170683457885043 0.7511917430069508 1.0 1.0 3 P43490 1
G0 and early g1 0.3771946265386791 0.301172060082421 0.7632832941160379 1.0 1.0 7 P24941,P11388 2
Synaptic adhesion like molecules 0.3758164998964881 0.2969363583879671 0.7665150973569479 1.0 1.0 7 P41440 1
Rho gtpases activate ktn1 0.375209034575353 0.2964587285703774 0.7668797808790755 1.0 1.0 9 P60953,P61586 2
Costimulation by the cd28 family 0.3640245773863618 0.2927325492524165 0.7697265884644453 1.0 1.0 16 P31751,Q6R327 2
Map2k and mapk activation 0.3696294701270968 0.2870872571516571 0.7740455090059937 1.0 1.0 12 P46940,Q9UHA4,Q02750,P28482,P27361 5
Apoptosis 0.4076861888692316 0.2818817451075732 0.778034187480475 1.0 1.0 89 P60900,P16403,Q99436,P27361,P31751,P49721,P26583,Q07812,P63167,Q16625,P09429,Q9BZF9,P07305,P28070,Q13200,Q9Y3B8,P15924,P28072,P35611,Q14997,P28482,P25054 22
Class a 1 rhodopsin like receptors 0.3705072885175722 0.28089294630024 0.7787925109771445 1.0 1.0 7 P42892 1
Peptide ligand binding receptors 0.3705072885175722 0.28089294630024 0.7787925109771445 1.0 1.0 7 P42892 1
Egfr downregulation 0.3693029581018807 0.2798837955360776 0.7795666598656998 1.0 1.0 10 Q9UBC2 1
Prolonged erk activation events 0.398847997708865 0.2798576867549529 0.779586691575956 1.0 1.0 5 P27361,P28482 2
Copi mediated anterograde transport 0.316964405134283 0.279096532662792 0.7801707439856644 1.0 1.0 54 O15020,P61923,Q9NZ32,P52907,Q13561,Q08379,P63167,P68371,P24390,Q9BUF5,O15498,P18085,O43731,Q9BVK6,Q9UBF2,O95249,Q92538,Q13885 18
Signaling by moderate kinase activity braf mutants 0.3666899566824845 0.2776698517519899 0.7812658056469395 1.0 1.0 12 P46940,P27361,Q02750,P28482 4
Meiotic recombination 0.3651469389052713 0.2770577213384033 0.7817357849472337 1.0 1.0 13 P35244,P24941 2
Toll like receptor tlr1 tlr2 cascade 0.3442613982649548 0.2761440510549228 0.782437427686675 1.0 1.0 21 Q9Y297,P61088,Q02750,P28482,Q9BQ95,P09429,P16220,P05067,P27361 9
Neddylation 0.3658297932382012 0.2752819439828555 0.783099635395796 1.0 1.0 73 Q9Y297,P28072,P49721,P60900 4
Neurotransmitter receptors and postsynaptic signal transmission 0.270057701817764 0.2728136257363805 0.7849964849208835 1.0 1.0 37 P35609,P63218,Q14168,P28482,P68371,Q9BUF5,Q9UBI6,P16220,P27361,Q13885 10
Response of mtb to phagocytosis 0.3661459721355806 0.2726005418279489 0.7851602953916168 1.0 1.0 11 P27361,O14964,P28482,P20339 4
Infection with mycobacterium tuberculosis 0.3661459721355806 0.2726005418279489 0.7851602953916168 1.0 1.0 11 P27361,O14964,P28482,P20339 4
Selenoamino acid metabolism 0.4095217725532193 0.2672852423664875 0.7892495484471376 1.0 1.0 91 P62899,P00390,P18621,P62750,P18124,P61513,P62241,P46779,P46776,P40429,Q9Y3U8,P83731,P27635,P61313,P61254,P62847,O43324,Q9P2J5,P08865,P39023,P46781,P62424,P49591,P46778,P36578,P42766,Q07020,P18077,Q02878,P60866,P62906,Q02543,P84098,P62917,P08708,P62910 36
Fgfr2 mutant receptor activation 0.3636715841252914 0.2627146975186699 0.7927704876272386 1.0 1.0 10 P19387,P35269 2
Signaling by fgfr2 iiia tm 0.3636715841252914 0.2627146975186699 0.7927704876272386 1.0 1.0 10 P19387,P35269 2
Pi metabolism 0.3491765763234936 0.2592681320588659 0.7954283658479617 1.0 1.0 18 Q8TBX8,Q8IY17,P20339 3
Signaling by nuclear receptors 0.3392363234032853 0.258974210008484 0.7956551392637821 1.0 1.0 64 P50750,P31751,P63218,Q01469,O14646,P35269,P28482,Q9UBI6,P19387,O94788,Q8NB78,P08559,O43815,P16220 14
Mrna capping 0.359130155478355 0.2579922429433592 0.7964128938663408 1.0 1.0 13 P19387,P18074,P35269,P13984 4
Striated muscle contraction 0.3620049696487262 0.2561334988147887 0.7978477562046273 1.0 1.0 7 P28289,P35609 2
Regulated necrosis 0.3481871893025391 0.2559048748554329 0.798024290345126 1.0 1.0 18 P41440,Q07812 2
Unwinding of dna 0.3614446320657029 0.2547812801294562 0.7988920345322494 1.0 1.0 9 P33993,Q9BRT9,P33991 3
P75 ntr receptor mediated signalling 0.3524042469051964 0.2536069585762524 0.7997992201929485 1.0 1.0 16 Q13501,Q92974,P61586,Q92888 4
Signaling by fgfr2 in disease 0.3584301956345854 0.252040740588153 0.8010095736021396 1.0 1.0 12 P19387,P35269 2
Mhc class ii antigen presentation 0.3194914427308762 0.2518059479517134 0.8011910596330356 1.0 1.0 57 Q9H0H5,Q9H0B6,O15020,Q9NZ32,P52907,O00139,Q13561,P63167,P68371,Q9BUF5,O95487,P07858,Q9Y6B6,Q13885 14
Anti inflammatory response favouring leishmania parasite infection 0.3513056938588265 0.2500505865135613 0.8025482284976699 1.0 1.0 16 Q9UBI6,P16220,P63218,P35579 4
Factors involved in megakaryocyte development and platelet production 0.292265430378537 0.2478825321958388 0.804225295485979 1.0 1.0 47 Q9H0H5,Q9H0B6,Q8IWA4,O00139,P20339,P60953,P24941,O60333,P68371,Q9BUF5,Q9H4M9,Q9BW19,Q13885 13
Diseases of carbohydrate metabolism 0.3572438775787933 0.2427020108474272 0.8082362495923516 1.0 1.0 9 P46976 1
Platelet homeostasis 0.356254845787251 0.2409470352038312 0.8095961669821252 1.0 1.0 10 Q9UBI6 1
Netrin 1 signaling 0.3554633343349958 0.2376752371787101 0.8121329912372166 1.0 1.0 9 P15311,P60953,Q16512 3
Apoptotic execution phase 0.2952387997631296 0.2294880932441683 0.8184895739319156 1.0 1.0 29 P35611,P07305,P26583,P16403,P15924,Q16625,P09429,P25054 8
Traf6 mediated nf kb activation 0.37910020364187 0.2294328712466376 0.8185324898998958 1.0 1.0 5 P09429 1
Hiv transcription initiation 0.3443958464889114 0.2282642226612392 0.8194408365415593 1.0 1.0 16 Q15545,P29083,P35269,P13984,P19387,P18074,P19447,Q92804 8
Assembly and cell surface presentation of nmda receptors 0.3495731032120451 0.2259690026305198 0.8212255291177495 1.0 1.0 12 P68371,Q9BUF5,P35609,Q14168 4
Rna polymerase iii transcription initiation from type 1 promoter 0.3488930410149194 0.2203200904305506 0.8256218746514219 1.0 1.0 10 Q9H1D9,O14802,Q9UKN8,O15160,P19388,Q9Y5Q8 6
Rna polymerase iii transcription 0.3481282797544242 0.2196503394811746 0.8261434834130659 1.0 1.0 11 Q9H1D9,O14802,Q9UKN8,O15160,P19388,Q9Y5Q8 6
Translation of sars cov 2 structural proteins 0.3392246524241711 0.2189301594182319 0.8267044524930975 1.0 1.0 17 Q10472,P78362,P39656,P49841,Q96SB4,P04844 6
Toll like receptor 9 tlr9 cascade 0.320535536316584 0.2176581126357567 0.8276955024465087 1.0 1.0 23 Q9Y297,P61088,Q02750,P28482,Q9BQ95,P09429,P16220,P05067,P27361 9
Negative regulation of mapk pathway 0.3478849525556022 0.2175731533849003 0.827761703879232 1.0 1.0 10 P27361,Q02750,P28482 3
Signal attenuation 0.4001856871561721 0.2146898913331342 0.8300091043674156 1.0 1.0 4 P28482 1
Synthesis of pips at the plasma membrane 0.3445995997874359 0.2099889613676583 0.8336762885183227 1.0 1.0 11 Q8TBX8,P20339 2
Rhoj gtpase cycle 0.3213717207041352 0.2079375137672249 0.8352777575500405 1.0 1.0 22 Q16512,P60953,Q9Y6M7,Q15758,P27105,O96013,P42167,Q9NSV4 8
Sensory processing of sound by outer hair cells of the cochlea 0.3392187478088417 0.2031915257224373 0.838985336174273 1.0 1.0 14 Q9Y2J2,Q00013,P35579 3
Heme degradation 0.3941139520188129 0.2021840232288139 0.8397728628221615 1.0 1.0 4 P53004 1
Cytoprotection by hmox1 0.334012903362429 0.199796773605325 0.8416395247445532 1.0 1.0 67 P28072,P49721,P60900 3
Intrinsic pathway of fibrin clot formation 0.6870929544108895 0.1966147692569874 0.8441290120169931 1.0 1.0 2 P42785 1
Formation of fibrin clot clotting cascade 0.6870929544108895 0.1966147692569874 0.8441290120169931 1.0 1.0 2 P42785 1
Uptake and function of anthrax toxins 0.5393484545362371 0.1960947916954003 0.8445359727478743 1.0 1.0 3 Q02750 1
Condensation of prophase chromosomes 0.3394392593366586 0.195308750805717 0.8451512468386224 1.0 1.0 10 P42695,Q01105,Q9UPP1 3
Activation of bh3 only proteins 0.3367636192428596 0.1932714951176052 0.8467463490336111 1.0 1.0 13 P31751,Q9Y3B8 2
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.5374509130817894 0.1929399510033069 0.8470059964470154 1.0 1.0 3 P24941 1
Post chaperonin tubulin folding pathway 0.3366614844557526 0.1882823155491666 0.8506553475811409 1.0 1.0 10 P68371,Q9BUF5,O75347,Q13885 4
Neuronal system 0.3002249387627935 0.1868900181728089 0.8517468656553924 1.0 1.0 55 P35609,P63218,P41440,Q9UM54,Q14168,P28482,P68371,P80404,Q9BUF5,Q9UBI6,P16220,P10586,O75915,P27361,Q13885 15
Syndecan interactions 0.3854200887344488 0.1851621545216552 0.8531018520813651 1.0 1.0 4 Q9Y296 1
Dna damage telomere stress induced senescence 0.3248579006663731 0.1771806357058724 0.8593665054843029 1.0 1.0 17 P54198,P24941,P16403 3
Dna replication 0.3903773434366441 0.1767579021792815 0.859698557489506 1.0 1.0 92 P49721,P60900,Q14997,Q9NRF9,P41440,Q9NR33,P28072,O43913,P35244 9
Ptk6 regulates cell cycle 0.6716992303137952 0.1747958806622561 0.8612400252628705 1.0 1.0 2 P24941 1
Integration of energy metabolism 0.3164934464630141 0.1734292808541703 0.8623140110253278 1.0 1.0 20 Q9UBI6,P29966,O00763,P63218 4
Signaling by fgfr4 0.3300141671941775 0.1727803720275798 0.8628240658471913 1.0 1.0 8 P28482 1
Signaling by fgfr1 0.3300141671941775 0.1727803720275798 0.8628240658471913 1.0 1.0 8 P28482 1
Signaling by fgfr3 0.3300141671941775 0.1727803720275798 0.8628240658471913 1.0 1.0 8 P28482 1
Intracellular signaling by second messengers 0.3938989612504675 0.1718466421672374 0.8635580957794164 1.0 1.0 94 P60900,Q99436,P27361,P31751,P49721,Q8TBX8,P28070,P67870,Q14839,Q13200,P28072,Q15910,P49815,P16220,Q14997,Q12873,P28482,Q6R327,P49841,O43815 20
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.5240438057602816 0.1717117111612561 0.8636641783952126 1.0 1.0 3 P06493 1
Activation of atr in response to replication stress 0.3124263610812715 0.1698950407254937 0.8650926813511906 1.0 1.0 21 O43913,P35244 2
Nuclear events stimulated by alk signaling in cancer 0.3276415377944505 0.1669451688236499 0.8674131922478827 1.0 1.0 11 P62753,P27361,P28482 3
Rho gtpases activate pkns 0.3141774211157873 0.1668175403364087 0.8675136168836852 1.0 1.0 20 Q9Y3B8,Q16513,P61586,Q7Z406 4
Rab regulation of trafficking 0.261581687386484 0.1659885466083762 0.8681659636185299 1.0 1.0 42 P31751,P20340,Q9Y3P9,P20339,Q5VZ89,Q15286,Q9H2M9,Q9Y296,P61106,P49815,Q9Y2L5 11
Activation of ampk downstream of nmdars 0.326251119235839 0.165521607958611 0.8685334437098049 1.0 1.0 7 P68371,Q9BUF5 2
Tbc rabgaps 0.3089561904073793 0.1599304750743673 0.8729358418588011 1.0 1.0 21 P49815,Q9Y3P9,P20339 3
S phase 0.4023259416520899 0.1589732939382355 0.8736899145772414 1.0 1.0 99 P31751,P49721,P60900,Q14997,Q9NRF9,P41440,Q9NR33,P28072,O43913,P35244,Q9BRT9 11
Mismatch repair 0.3234012247267756 0.157953581493758 0.8744933760412987 1.0 1.0 12 P35244 1
Flt3 signaling in disease 0.3204862140527729 0.1530641428226647 0.878347692498326 1.0 1.0 7 Q9UBW7,Q01082,Q06124,P22681,Q14789,P62993 6
Signaling by alk in cancer 0.2464523183598221 0.1517737517637802 0.8793653853250734 1.0 1.0 34 P35579,Q9P2E9,P33176,P28482,Q13501,P62753,P06753,O43815,P27361 9
Nef mediated cd4 down regulation 0.3189093064611759 0.1516840459952878 0.8794361410105487 1.0 1.0 6 Q9UI12,P63010,Q96CW1,P53680,O94973 5
Nef mediated cd8 down regulation 0.3189093064611759 0.1516840459952878 0.8794361410105487 1.0 1.0 6 Q9UI12,P63010,Q96CW1,P53680,O94973 5
Trafficking of glur2 containing ampa receptors 0.3189093064611756 0.1516840459952875 0.8794361410105489 1.0 1.0 6 P63010,Q96CW1,P53680,O94973,P46459 5
Vldlr internalisation and degradation 0.3190038541357828 0.1499602930110774 0.8807959425256451 1.0 1.0 7 P09496,P63010,Q96CW1,P53680,O94973,Q00610 6
Wnt5a dependent internalization of fzd2 fzd5 and ror2 0.3190038541357828 0.1499602930110774 0.8807959425256451 1.0 1.0 7 P09496,P63010,Q96CW1,P53680,O94973,Q00610 6
Epigenetic regulation of gene expression 0.2680592054851241 0.1498153490543933 0.880910299239178 1.0 1.0 46 P26358,Q9UIF9,P18074,Q13185,Q9NR30,P19447,O00422,P17480,O75182,Q14839,O15160,P35659,Q15910,Q13330,Q86YP4,Q12873,Q9H0E3,P49841,O75533,Q9NY93 20
Retrograde neurotrophin signalling 0.3190984578884871 0.1487160104639722 0.8817777272060376 1.0 1.0 8 P09496,P63010,P50570,Q96CW1,P53680,O94973,Q00610 7
Rna polymerase i transcription initiation 0.3071304478968277 0.1475698814649789 0.8826822259200875 1.0 1.0 20 Q86YP4,P17480,Q12873,Q14839,O15160,P18074,Q13330 7
Post translational modification synthesis of gpi anchored proteins 0.3170371225364238 0.1444243228063388 0.8851654113294256 1.0 1.0 8 O43292 1
Transport to the golgi and subsequent modification 0.349591365096341 0.1435975311582562 0.8858182903024574 1.0 1.0 79 P52907,Q13561,P68371,P24390,Q9UBF2,Q9Y6B6,O15020,P63167,Q9BUF5,O43731,P33908,Q9NZ32,P04066,O15027,O60476,O15498,P18085,Q9Y296,Q92538,P61923,Q5JRA6,Q08379,Q9BVK6,O95249,O95487,Q13885 26
Signaling by wnt in cancer 0.3165586230809077 0.142426983895458 0.8867427495810869 1.0 1.0 9 P49841 1
Antigen presentation folding assembly and peptide loading of class i mhc 0.308233996874684 0.1349354522814423 0.8926629090048508 1.0 1.0 17 Q6P179 1
Rna polymerase ii transcribes snrna genes 0.2731255855303676 0.1308408259623039 0.8959012261412882 1.0 1.0 28 P50750,Q8N201,P35269,P13984,P19387,Q96HW7,Q96CB8,Q68E01 8
Trans golgi network vesicle budding 0.2359704819170408 0.1253149825931986 0.9002741912906755 1.0 1.0 36 O75976,O00203,Q92572,O43633,P51809,Q99523,Q9H3P7,O14964,Q92538,P11717,P05067,O43747,Q10567 13
Er quality control compartment erqc 0.3487594669436583 0.1249965780210344 0.9005262594368306 1.0 1.0 4 Q13438 1
Positive epigenetic regulation of rrna expression 0.2615331713162811 0.1243206188628512 0.9010614224526016 1.0 1.0 30 O00159,Q86YP4,O94776,Q12873,Q14839,O15160,P35659,O60264,P19388,P49841,Q9BQG0,Q9UIG0,Q13185,O75533,Q9NY93,Q13547,Q9NR30,Q13330 18
Regulation of expression of slits and robos 0.4490198389226227 0.1225958960141165 0.902427104435187 1.0 1.0 124 O43242,P62899,P60900,P18621,P62750,P18124,P61513,P62241,Q99436,P46779,P46776,P49721,P40429,Q9Y3U8,P83731,P27635,P61313,Q9BZI7,P61254,P62847,P25787,P25789,P28070,P08865,P39023,P46781,P62424,Q13200,P46778,P36578,P28072,P42766,Q15287,Q07020,P18077,Q02878,P60866,Q14997,P62906,Q02543,P84098,P62753,P62917,P08708,P62910 45
Cilium assembly 0.3110919063906722 0.1216506909778449 0.903175665987604 1.0 1.0 66 Q13561,Q96A65,O43805,Q9BV73,P41208,Q66GS9,A6NIH7 7
Semaphorin interactions 0.2876382829712906 0.1188034656992719 0.9054310629022906 1.0 1.0 23 O75116,P61586,Q7Z406,P49841 4
Activation of rac1 0.3027289601308927 0.1185687300640528 0.9056170403420178 1.0 1.0 7 O96013,Q16512 2
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.3040911809543633 0.1171652544183177 0.9067291001923709 1.0 1.0 10 Q9UI12,Q96CW1,O94973,O43747,Q10567 5
Antigen processing ubiquitination proteasome degradation 0.3796222583118644 0.1153695587170483 0.9081522064445672 1.0 1.0 95 Q9Y297,P49721,P60900,P19474,Q9UIQ6,P28072,P55786 7
Signaling by flt3 fusion proteins 0.3202962962962997 0.1147498081757508 0.908643433428732 1.0 1.0 5 Q9UBW7,Q14789,P62993,Q01082 4
Formation of the early elongation complex 0.2990349649454851 0.1144105220211437 0.9089123734003082 1.0 1.0 17 P35269,P13984,P19387,P18074,Q9H3P2 5
Abortive elongation of hiv 1 transcript in the absence of tat 0.3011239902003966 0.1139925587928812 0.9092436922163438 1.0 1.0 15 P19387,P35269,Q9H3P2 3
Fceri mediated mapk activation 0.3013317995048704 0.1121044715553759 0.910740571989392 1.0 1.0 10 P27361,P45985,P28482 3
Diseases of mismatch repair mmr 0.4734971868522225 0.1082239714667634 0.9138180301503314 1.0 1.0 3 P20585,P43246 2
Estrogen dependent gene expression 0.2500967758040023 0.1044370047995558 0.9168225576488472 1.0 1.0 31 P50750,O14646,P35269 3
Long term potentiation 0.2916960084717301 0.1022500999739534 0.918558162079602 1.0 1.0 6 Q14168 1
Unblocking of nmda receptors glutamate binding and activation 0.2916960084717301 0.1022500999739534 0.918558162079602 1.0 1.0 6 Q14168 1
Ras activation upon ca2 influx through nmda receptor 0.2916960084717301 0.1022500999739534 0.918558162079602 1.0 1.0 6 Q14168 1
Nef mediated downregulation of mhc class i complex cell surface expression 0.3287839665318656 0.1000075446594957 0.9203383357045882 1.0 1.0 4 Q10567 1
Signaling by fgfr in disease 0.2836952090714695 0.0930662234782204 0.9258509507023897 1.0 1.0 20 P35269,O15164 2
Disorders of transmembrane transporters 0.3283651322157129 0.0913897510873056 0.9271829051178776 1.0 1.0 77 P49721,P60900,Q14997,Q9BVL2,P28072,O15504 6
Aggrephagy 0.2872671524078521 0.0893340603090877 0.9288164260598704 1.0 1.0 16 P68371,Q9BUF5,P61088,P63167 4
Receptor mediated mitophagy 0.4507646987456788 0.0877616225668143 0.9300661407811333 1.0 1.0 3 P67870 1
Apoptotic cleavage of cellular proteins 0.2822207067335875 0.0841277138218209 0.9329548903010418 1.0 1.0 18 Q13464,P35611,Q15149,Q9UDY2,P15924,Q16625,Q13813,P25054,Q14126 9
Kinesins 0.2724365996160031 0.0840047417294973 0.9330526617419708 1.0 1.0 23 Q9H0H5,Q9H0B6,O00139,O60333,P68371,Q9BUF5,Q9BW19 7
Tfap2 ap 2 family regulates transcription of growth factors and their receptors 0.5778567199526463 0.0826157208689062 0.9341571005636522 1.0 1.0 2 P00533 1
Signaling by erbb2 0.2839278235012316 0.0825034593352436 0.9342463675633206 1.0 1.0 15 P31751 1
Pyruvate metabolism 0.2827677885879077 0.0815864021889319 0.93497561472476 1.0 1.0 16 O95563 1
Signaling by braf and raf1 fusions 0.2712541632511142 0.0815842937162988 0.9349772914529316 1.0 1.0 23 O00203,Q99996,P27448,Q96PU8,P46940,Q02750,P28482,Q6WCQ1,P30086,O15164,P27361 11
Signal regulatory protein family interactions 0.4400355344980606 0.0796890856800536 0.9364845402118444 1.0 1.0 3 P62993,Q08722 2
Dna strand elongation 0.2535406757885835 0.078076992284675 0.9377668088116862 1.0 1.0 28 P41440,P35244 2
Sema3a pak dependent axon repulsion 0.2757189445597354 0.0772069023693116 0.9384589507427704 1.0 1.0 7 Q16512,Q13177,P07900,P23528,P63000,P08238 6
Protein folding 0.2233341380534401 0.0738720817101836 0.9411121707030624 1.0 1.0 37 P63218,Q86WA8,P67870,Q9UBI6,P68371,Q9BUF5 6
Mitophagy 0.2747477981231274 0.0697686347079309 0.9443778121997268 1.0 1.0 11 Q9NS69,Q13501,P67870,Q8IWA4 4
Gamma carboxylation hypusine formation and arylsulfatase activation 0.2740041130101771 0.0687942833071312 0.9451533685688192 1.0 1.0 11 P38435,O60725 2
Rna polymerase i transcription termination 0.2721401858477595 0.0675813606078021 0.9461188935514576 1.0 1.0 10 P17480,P18074,O15160 3
Eph ephrin signaling 0.2360551124737382 0.0664999329053028 0.9469798111268222 1.0 1.0 31 Q15375,Q13464,Q92747,P35579,Q16512,P60953,O75116,P61586,P35580,Q7Z406 10
Stat3 nuclear events downstream of alk signaling 0.4166419899318799 0.0652793671735871 0.947951569909143 1.0 1.0 3 Q92769,Q13547 2
Collagen biosynthesis and modifying enzymes 0.2687567709608763 0.0612324209834542 0.951174109956524 1.0 1.0 12 P13674,O75718 2
Transcription of e2f targets under negative control by dream complex 0.2781398104265369 0.0586556557796531 0.953226380049947 1.0 1.0 4 Q99741,Q13547,P11388 3
Selective autophagy 0.2320274394255541 0.0571939086769246 0.9543907303911532 1.0 1.0 31 Q9NS69,Q8IWA4,P61088,P67870,P63167,P68371,Q9BUF5,Q13501,Q13885 9
Negative regulation of nmda receptor mediated neuronal transmission 0.2595552384029125 0.0565653175637092 0.9548914628642308 1.0 1.0 8 Q14168 1
Formation of tubulin folding intermediates by cct tric 0.2613602613602631 0.051778025977316 0.958705564789922 1.0 1.0 13 Q99832,P78371,P50990,P50991,Q13509,P68371,Q9BUF5,P17987,P49368,Q9BVA1,P40227,Q13885 12
Nephrin family interactions 0.2580052578478335 0.0516317040432112 0.958822156849538 1.0 1.0 10 P46940,Q13813,P12814,P35609 4
Chrebp activates metabolic gene expression 0.254225173589643 0.0480674654462984 0.9616624750336256 1.0 1.0 4 P49327,O00763 2
Sensory processing of sound 0.2570614888364729 0.0471413920144728 0.9624005379344328 1.0 1.0 19 Q9Y2J2,Q00013,P52907,P35579 4
Rho gtpases activate paks 0.2554765645630469 0.045524861258878 0.963688959019224 1.0 1.0 13 P60953,Q16512,Q7Z406,P35579 4
Met activates pi3k akt signaling 0.4807578448786391 0.0454299067270459 0.9637646434686382 1.0 1.0 2 Q9NWH9 1
Sumo is conjugated to e1 uba2 sae1 0.3547432978647614 0.0438863927769018 0.964994961842008 1.0 1.0 3 Q9UBT2 1
Processing and activation of sumo 0.3547432978647614 0.0438863927769018 0.964994961842008 1.0 1.0 3 Q9UBT2 1
Sumo is transferred from e1 to e2 ube2i ubc9 0.3547432978647614 0.0438863927769018 0.964994961842008 1.0 1.0 3 Q9UBT2 1
Mtor signalling 0.2534500885203551 0.0426523255344696 0.965978683667795 1.0 1.0 19 P49815 1
Hats acetylate histones 0.2462227725989084 0.0422128245939687 0.9663290391262374 1.0 1.0 24 Q9Y4A5,O96019,Q9H0E9,O95251 4
Transport and synthesis of paps 0.4517465956187246 0.0412102975925947 0.9671282443561464 1.0 1.0 2 Q8TB61 1
Activated ntrk2 signals through cdk5 0.449378330373013 0.0409515497231037 0.9673345211515988 1.0 1.0 2 P63000 1
Gp1b ix v activation signalling 0.4478981645944498 0.040795490243201 0.967458934632279 1.0 1.0 2 P21333 1
Rna polymerase i transcription 0.2445183561455418 0.0397843863704068 0.9682650242476348 1.0 1.0 24 Q86YP4,P17480,Q12873,Q14839,O15160,P19447,P18074,P27361,Q13330 9
P75ntr negatively regulates cell cycle via sc1 0.4215512137359477 0.0386496407231866 0.9691697242613088 1.0 1.0 2 Q13547 1
Response of eif2ak1 hri to heme deficiency 0.3132958246964638 0.0383875375087338 0.9693786972866164 1.0 1.0 3 P08243,P20042 2
Rna polymerase iii transcription initiation from type 3 promoter 0.2323651452282179 0.0382538733213301 0.969485267601266 1.0 1.0 6 Q9H1D9,O14802,O15160,P19388,P62875 5
Rna polymerase iii chain elongation 0.2323651452282179 0.0382538733213301 0.969485267601266 1.0 1.0 6 Q9H1D9,O14802,O15160,P19388,P62875 5
Dscam interactions 0.3061889250814225 0.037858852637066 0.9698002203508448 1.0 1.0 3 P63000,Q16512 2
Golgi to er retrograde transport 0.3080857439661075 0.0371025169575947 0.9704032651699162 1.0 1.0 78 Q10472,Q9H0H5,Q9H0B6,P52907,Q13561,Q10471,P68371,P24390,Q9UBF2,P68402,P63167,Q9NZ43,Q9BUF5,O43731,Q9H2M9,Q9BW19,Q9NZ32,P18085,Q92538,P61923,P20340,O00139,O60333,Q9BVK6,Q13885 25
Nonhomologous end joining nhej 0.2489430099436451 0.0370498316755507 0.9704452730601912 1.0 1.0 18 Q9NXR7 1
Glutathione conjugation 0.2473078006601648 0.0368873325464223 0.970574840038023 1.0 1.0 14 P48637,Q96KP4,Q99735 3
Rna polymerase iii transcription termination 0.2324340349836884 0.0362663498712933 0.9710699811921912 1.0 1.0 7 Q9H1D9,O14802,O15160,P19388,P05455,P62875 6
Creatine metabolism 0.3093546477205436 0.0362515423051952 0.9710817881566384 1.0 1.0 2 P12532 1
Er to golgi anterograde transport 0.2977500479070935 0.0309842969252655 0.975282062899014 1.0 1.0 75 P52907,Q13561,P68371,P24390,Q9UBF2,Q9Y6B6,O15020,P63167,Q9BUF5,O43731,Q9NZ32,O15027,O15498,P18085,Q9Y296,Q92538,P61923,Q5JRA6,Q08379,Q9BVK6,O95249,O95487,Q13885 23
The role of nef in hiv 1 replication and disease pathogenesis 0.2313157844152154 0.0271567762080395 0.9783346905684452 1.0 1.0 12 Q9UI12,Q9BXS5,Q96CW1,O94973,O43747,Q10567 6
Host interactions of hiv factors 0.3434464167470682 0.02504663631256 0.9800177648638896 1.0 1.0 96 P50750,Q9Y297,P49721,P60900,Q14997,Q9BVL2,P28072 7
Copi dependent golgi to er retrograde traffic 0.2407535340663503 0.0231073702426276 0.9815646266535688 1.0 1.0 53 Q9H0H5,Q9H0B6,P61923,O00139,O60333,Q9BVK6,P68371,P24390,Q9NZ43,Q9BUF5,P18085,O43731,Q9UBF2,Q92538,Q9BW19,Q13885 16
Deadenylation dependent mrna decay 0.2133608366308938 0.0216365992957996 0.9827378383424924 1.0 1.0 42 Q9NZN8,Q14240,Q9H074 3
B wich complex positively regulates rrna expression 0.2301721208589193 0.0200588470157405 0.9839964288582256 1.0 1.0 19 O00159,O15160,P35659,O60264,P19388,P49841,Q9BQG0,Q9UIG0,O75533,Q9NY93,Q9NR30 11
Signaling by robo receptors 0.4423486330751164 0.0199599693251322 0.9840753060490736 1.0 1.0 142 O43242,P62899,P60900,P60953,P18621,P35080,P62750,P18124,P61513,P62241,O96013,Q99436,P46779,P46776,P49721,P40429,Q9Y3U8,P83731,P27635,P61313,Q9BZI7,P61586,P61254,P62847,P25787,P25789,P28070,P08865,P39023,P46781,P62424,Q13200,P46778,P36578,P28072,P42766,Q15287,Q07020,P18077,Q02878,P60866,Q14997,Q16512,O75122,P62906,Q02543,P84098,P62753,P62917,P08708,P62910 51
Chromatin modifying enzymes 0.276904761439967 0.0195373964987119 0.9844124046381808 1.0 1.0 69 Q9Y4A5,O96019,Q9UBU8,O00422,Q9H0E9,Q8WTS6,Q12873,Q14839,Q9UPP1,Q15910,Q8NB78,P29375,O95251,Q03164,Q15047 15
E3 ubiquitin ligases ubiquitinate target proteins 0.2262187871581454 0.0193351538297312 0.9845737404643228 1.0 1.0 16 P78527,Q6P1J9,P12004,P61088,O75381,Q14527,O75150,Q9GZS3,Q6PD62,P68036,Q9BUN8,P50542,P55072,Q8N7H5,Q5VTR2 15
Cellular response to chemical stress 0.2919800180228669 0.017202532926906 0.9862750415055408 1.0 1.0 76 P28072,P49721,P60900 3
Depolymerisation of the nuclear lamina 0.1927460880535038 0.0160950177840462 0.987158588233747 1.0 1.0 9 Q8NC56,P42167,P50402 3
Eukaryotic translation initiation 0.351405831705655 0.0159289832108691 0.9872910476747528 1.0 1.0 102 P62899,P18621,P62750,P18124,P61513,P55010,P62241,P46779,P46776,P40429,Q9Y3U8,P83731,P27635,P61313,P61254,P62847,Q14240,P08865,P39023,P46781,Q13144,P62424,P46778,P36578,P42766,P06730,Q07020,P18077,Q02878,P60866,P62906,Q13347,Q02543,P84098,P62917,P08708,P62910 37
Programmed cell death 0.3534071956736463 0.0155216553652511 0.9876160080901996 1.0 1.0 103 P60900,P16403,Q99436,P27361,P31751,P49721,P26583,Q07812,P63167,Q16625,P09429,Q9BZF9,P07305,P28070,Q13200,Q9Y3B8,P15924,P28072,P35611,Q14997,P41440,P28482,P25054 23
Cytosolic trna aminoacylation 0.2231158772713874 0.0147990155628343 0.9881925249631198 1.0 1.0 23 P49589,Q15046,P41250,P54136,P49588,P07814,P56192,P47897,O43324,P54577,Q9P2J5,P49591,P23381,Q15181,Q9NSD9,O43776,P41252,Q12904,P14868,P26639,P26640,Q9Y285 22
Cohesin loading onto chromatin 0.192760806112157 0.0144765605393939 0.9884497792850075 1.0 1.0 10 Q6KC79 1
Dna double strand break response 0.2218003998673147 0.0134907635320265 0.9892362545668792 1.0 1.0 22 Q9NXR7 1
Nuclear pore complex npc disassembly 0.2062652168184678 0.012872240107034 0.9897297219779756 1.0 1.0 31 Q9BVL2,O95067 2
Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0.2070979860401457 0.0112791352738084 0.9910007429188123 1.0 1.0 15 O96019,P67870,Q969G3,P19784 4
Phase ii conjugation of compounds 0.2085823851706522 0.0060320475337915 0.9951871515891706 1.0 1.0 27 Q9NZL9,Q9NX62,P48637,Q96KP4,Q99735 5
Deubiquitination 0.3229406500706502 0.0051244003691234 0.9959113379564676 1.0 1.0 93 Q9Y4A5,P49721,P60900,Q14997,Q9NXR7,P61586,P28072,Q9Y4E8 8